ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
FMIBIEHO_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FMIBIEHO_00002 2.62e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
FMIBIEHO_00003 9.71e-317 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00004 1.45e-46 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
FMIBIEHO_00005 6.14e-259 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FMIBIEHO_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FMIBIEHO_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FMIBIEHO_00008 6.02e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
FMIBIEHO_00009 6.56e-165 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
FMIBIEHO_00010 1.33e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FMIBIEHO_00011 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
FMIBIEHO_00012 2.63e-99 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
FMIBIEHO_00013 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
FMIBIEHO_00014 2.18e-268 - - - E - - - Major Facilitator Superfamily
FMIBIEHO_00015 8.32e-66 - - - - - - - -
FMIBIEHO_00018 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
FMIBIEHO_00019 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMIBIEHO_00020 1.09e-307 yycH - - S - - - YycH protein
FMIBIEHO_00021 2.05e-185 yycI - - S - - - YycH protein
FMIBIEHO_00022 5.49e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
FMIBIEHO_00023 9.52e-270 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
FMIBIEHO_00024 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FMIBIEHO_00025 3.03e-94 ywnA - - K - - - Transcriptional regulator
FMIBIEHO_00026 1.09e-223 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
FMIBIEHO_00027 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
FMIBIEHO_00028 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
FMIBIEHO_00029 7.69e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
FMIBIEHO_00030 1.16e-139 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 transmembrane transport
FMIBIEHO_00031 1.79e-245 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FMIBIEHO_00032 2.32e-234 - - - D ko:K06889 - ko00000 Alpha beta
FMIBIEHO_00033 7.18e-234 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMIBIEHO_00034 5.91e-279 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FMIBIEHO_00035 5.71e-48 - - - - - - - -
FMIBIEHO_00036 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
FMIBIEHO_00037 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FMIBIEHO_00038 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
FMIBIEHO_00039 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
FMIBIEHO_00040 1.26e-210 - - - C - - - Aldo keto reductase
FMIBIEHO_00041 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
FMIBIEHO_00042 3.67e-86 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
FMIBIEHO_00043 2.15e-242 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
FMIBIEHO_00044 1.13e-166 ybhF_2 - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
FMIBIEHO_00045 1.58e-122 - - - K - - - transcriptional regulator
FMIBIEHO_00046 2.81e-212 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FMIBIEHO_00047 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FMIBIEHO_00048 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
FMIBIEHO_00049 8.04e-124 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FMIBIEHO_00050 5.85e-169 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
FMIBIEHO_00051 1.03e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FMIBIEHO_00052 1.12e-185 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00053 5.46e-104 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00054 3.97e-62 - - - - - - - -
FMIBIEHO_00055 0.0 tagE6 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
FMIBIEHO_00056 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
FMIBIEHO_00057 2.71e-197 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
FMIBIEHO_00058 2.85e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FMIBIEHO_00059 1.64e-142 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
FMIBIEHO_00060 2.41e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
FMIBIEHO_00061 1.16e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_00062 5.73e-302 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00063 3.1e-309 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FMIBIEHO_00064 2.11e-105 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
FMIBIEHO_00065 4.8e-310 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
FMIBIEHO_00066 3.78e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMIBIEHO_00067 3.58e-303 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
FMIBIEHO_00068 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
FMIBIEHO_00069 1.69e-09 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
FMIBIEHO_00070 1.75e-276 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
FMIBIEHO_00071 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
FMIBIEHO_00072 4.3e-314 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FMIBIEHO_00074 4.91e-240 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
FMIBIEHO_00076 3.98e-288 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
FMIBIEHO_00077 4.66e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_00078 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
FMIBIEHO_00079 4.43e-272 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
FMIBIEHO_00080 3.28e-185 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
FMIBIEHO_00081 6.1e-172 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
FMIBIEHO_00082 5.7e-210 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
FMIBIEHO_00083 1.3e-189 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
FMIBIEHO_00084 1.47e-41 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
FMIBIEHO_00085 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
FMIBIEHO_00086 5.59e-174 - - - S - - - Protein of unknown function (DUF1129)
FMIBIEHO_00087 1.71e-264 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
FMIBIEHO_00088 1.21e-222 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
FMIBIEHO_00089 5.79e-171 epsB - - M - - - biosynthesis protein
FMIBIEHO_00090 1.36e-146 ywqD - - D - - - Capsular exopolysaccharide family
FMIBIEHO_00091 5.63e-178 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
FMIBIEHO_00092 5.79e-167 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
FMIBIEHO_00093 4.41e-123 tuaA - - M - - - Bacterial sugar transferase
FMIBIEHO_00094 4.08e-111 - - - M - - - Glycosyl transferase family 2
FMIBIEHO_00095 1.4e-197 is18 - - L - - - COG2801 Transposase and inactivated derivatives
FMIBIEHO_00096 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
FMIBIEHO_00097 9.8e-48 - - - M - - - Glycosyltransferase, group 1 family protein
FMIBIEHO_00098 5.01e-195 - - - L - - - MULE transposase domain
FMIBIEHO_00103 1.44e-56 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_00104 1.08e-10 - - - E - - - Protein of unknown function (DUF3923)
FMIBIEHO_00105 1.95e-290 - - - L - - - MULE transposase domain
FMIBIEHO_00106 1.95e-290 - - - L - - - MULE transposase domain
FMIBIEHO_00108 2.13e-50 murJ - - S ko:K03980 - ko00000,ko01011,ko02000 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
FMIBIEHO_00110 3.64e-201 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00111 1.11e-85 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_00112 8.72e-85 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
FMIBIEHO_00113 3.52e-25 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_00114 1.81e-84 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_00115 1.65e-122 - - - S ko:K09705 - ko00000 Cupin superfamily (DUF985)
FMIBIEHO_00116 5.24e-159 vanR - - K - - - response regulator
FMIBIEHO_00117 3.09e-267 hpk31 - - T - - - Histidine kinase
FMIBIEHO_00118 2.78e-268 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FMIBIEHO_00119 2.19e-190 - - - E - - - AzlC protein
FMIBIEHO_00120 2.14e-78 - - - S - - - branched-chain amino acid
FMIBIEHO_00121 9e-129 - - - S ko:K07002 - ko00000 Serine hydrolase
FMIBIEHO_00122 7.36e-294 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
FMIBIEHO_00123 9.9e-33 - - - K - - - transcriptional regulator
FMIBIEHO_00124 9.95e-12 - - - K - - - Bacterial regulatory proteins, tetR family
FMIBIEHO_00125 5.73e-223 ydbI - - K - - - AI-2E family transporter
FMIBIEHO_00126 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
FMIBIEHO_00127 8.26e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FMIBIEHO_00128 5.86e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FMIBIEHO_00129 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FMIBIEHO_00130 1.45e-223 hrpQ 4.6.1.1 - T ko:K01768,ko:K03220,ko:K10914 ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111 ko00000,ko00001,ko00002,ko01000,ko02044,ko03000 histone H2A K63-linked ubiquitination
FMIBIEHO_00131 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
FMIBIEHO_00132 1.21e-14 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
FMIBIEHO_00133 5.04e-173 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
FMIBIEHO_00134 1.36e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMIBIEHO_00135 4e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMIBIEHO_00136 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FMIBIEHO_00137 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FMIBIEHO_00138 4.8e-251 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
FMIBIEHO_00139 1.13e-139 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FMIBIEHO_00140 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
FMIBIEHO_00141 2.75e-307 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
FMIBIEHO_00142 1.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FMIBIEHO_00143 6.98e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FMIBIEHO_00144 7.08e-227 - - - - - - - -
FMIBIEHO_00145 2.63e-68 - - - S - - - Cupredoxin-like domain
FMIBIEHO_00146 2.79e-69 - - - S - - - Cupredoxin-like domain
FMIBIEHO_00147 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
FMIBIEHO_00148 1.2e-32 - - - EGP - - - Major Facilitator
FMIBIEHO_00149 6.87e-117 yejD 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 nucleoside 2-deoxyribosyltransferase
FMIBIEHO_00152 4.43e-36 - - - S - - - Domain of unknown function (DUF4767)
FMIBIEHO_00153 3.06e-57 yodA - - S - - - Tautomerase enzyme
FMIBIEHO_00154 2.7e-25 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
FMIBIEHO_00155 3.17e-156 pnb - - C - - - nitroreductase
FMIBIEHO_00156 4.11e-134 - 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha/beta hydrolase family
FMIBIEHO_00157 6.36e-100 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FMIBIEHO_00158 1.88e-46 - - - C - - - Aldo keto reductase
FMIBIEHO_00159 1.43e-31 - - - C - - - Aldo keto reductase
FMIBIEHO_00160 5.11e-06 - - - S - - - CsbD-like
FMIBIEHO_00162 1.26e-06 - - - C - - - Aldo/keto reductase family
FMIBIEHO_00163 2.02e-116 - - - P - - - Cadmium resistance transporter
FMIBIEHO_00164 8.58e-71 - 4.1.1.44 - O ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FMIBIEHO_00165 9.97e-121 - - - - - - - -
FMIBIEHO_00166 0.0 - - - M - - - Iron Transport-associated domain
FMIBIEHO_00167 5.34e-129 - - - M ko:K14193 ko05150,map05150 ko00000,ko00001 Iron Transport-associated domain
FMIBIEHO_00168 7.99e-196 isdE - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
FMIBIEHO_00169 8.57e-199 isdF - - U ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMIBIEHO_00170 4.45e-181 - 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_00171 9.56e-303 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
FMIBIEHO_00172 2.48e-28 - - - - - - - -
FMIBIEHO_00173 1.05e-49 - - - - - - - -
FMIBIEHO_00174 2e-203 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
FMIBIEHO_00175 8.34e-101 - - - - - - - -
FMIBIEHO_00176 6.62e-231 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMIBIEHO_00177 7.88e-192 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class-V
FMIBIEHO_00178 1.04e-53 - - - C - - - Protein of unknown function (DUF1116)
FMIBIEHO_00179 3.63e-07 - - - S - - - Protein of unknown function (DUF2877)
FMIBIEHO_00180 2.05e-155 cpkA 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Amino acid kinase family
FMIBIEHO_00181 7.41e-227 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
FMIBIEHO_00182 3.88e-160 - - - C - - - nitroreductase
FMIBIEHO_00183 8.06e-176 - - - E - - - GDSL-like Lipase/Acylhydrolase family
FMIBIEHO_00184 1.06e-70 - - - S - - - Mazg nucleotide pyrophosphohydrolase
FMIBIEHO_00185 1.92e-106 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_00186 1.61e-295 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00187 5.19e-251 adh1 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
FMIBIEHO_00188 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
FMIBIEHO_00189 2.15e-47 - - - C - - - Aldo keto reductase
FMIBIEHO_00190 2.16e-210 - - - K - - - Transcriptional regulator
FMIBIEHO_00192 3.03e-181 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
FMIBIEHO_00194 1.21e-189 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
FMIBIEHO_00195 6.37e-259 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
FMIBIEHO_00196 0.0 - - - L - - - DNA helicase
FMIBIEHO_00197 7.95e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
FMIBIEHO_00198 5.79e-288 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
FMIBIEHO_00199 9.16e-240 - - - - - - - -
FMIBIEHO_00200 2.31e-165 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
FMIBIEHO_00201 2.38e-272 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
FMIBIEHO_00202 2.01e-208 yunF - - F - - - Protein of unknown function DUF72
FMIBIEHO_00203 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FMIBIEHO_00204 3.29e-189 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
FMIBIEHO_00205 6.51e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
FMIBIEHO_00206 6.18e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
FMIBIEHO_00207 4.04e-205 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FMIBIEHO_00208 1.65e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
FMIBIEHO_00209 1.98e-123 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
FMIBIEHO_00210 2.81e-166 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
FMIBIEHO_00211 2.13e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
FMIBIEHO_00212 9.91e-302 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FMIBIEHO_00213 7.69e-228 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FMIBIEHO_00214 1.89e-78 - - - - - - - -
FMIBIEHO_00215 1.43e-184 yidA - - S - - - hydrolase
FMIBIEHO_00216 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
FMIBIEHO_00217 5.23e-97 ywiB - - S - - - Domain of unknown function (DUF1934)
FMIBIEHO_00218 2.16e-97 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
FMIBIEHO_00219 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
FMIBIEHO_00220 4.36e-302 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FMIBIEHO_00221 3.85e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
FMIBIEHO_00222 6.44e-62 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
FMIBIEHO_00223 8.65e-70 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
FMIBIEHO_00224 3.88e-106 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_00225 1.35e-302 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00226 5.38e-158 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
FMIBIEHO_00227 2.47e-59 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FMIBIEHO_00228 9.6e-119 lemA - - S ko:K03744 - ko00000 LemA family
FMIBIEHO_00229 1.9e-202 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
FMIBIEHO_00230 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
FMIBIEHO_00231 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
FMIBIEHO_00232 1.18e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
FMIBIEHO_00233 6.25e-268 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FMIBIEHO_00234 7.09e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
FMIBIEHO_00235 4.51e-148 - - - S - - - (CBS) domain
FMIBIEHO_00236 5.39e-130 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
FMIBIEHO_00237 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FMIBIEHO_00238 2.47e-53 yabO - - J - - - S4 domain protein
FMIBIEHO_00239 5.88e-74 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
FMIBIEHO_00240 1.65e-113 yabR - - J ko:K07571 - ko00000 RNA binding
FMIBIEHO_00241 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
FMIBIEHO_00242 5.21e-126 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
FMIBIEHO_00243 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FMIBIEHO_00244 3.89e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FMIBIEHO_00245 2.64e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FMIBIEHO_00246 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
FMIBIEHO_00249 8.34e-101 - - - - - - - -
FMIBIEHO_00252 3.22e-77 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00253 4.13e-61 - - - L - - - MULE transposase domain
FMIBIEHO_00254 3.02e-61 - - - L - - - MULE transposase domain
FMIBIEHO_00255 7.9e-289 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FMIBIEHO_00256 2.69e-256 - - - L - - - Integrase core domain
FMIBIEHO_00257 0.0 - 1.7.2.5 - P ko:K04561 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Cytochrome C and Quinol oxidase polypeptide I
FMIBIEHO_00258 3.12e-31 pacL - - P - - - Cation transporter/ATPase, N-terminus
FMIBIEHO_00259 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
FMIBIEHO_00261 1.87e-156 - - - - - - - -
FMIBIEHO_00262 4.78e-135 - - - S - - - Domain of unknown function (DUF4767)
FMIBIEHO_00263 1.58e-70 - - - K - - - Helix-turn-helix domain
FMIBIEHO_00264 5.38e-222 - 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
FMIBIEHO_00265 1.1e-07 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
FMIBIEHO_00266 6.8e-95 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
FMIBIEHO_00267 4.36e-67 ybjQ - - S - - - Belongs to the UPF0145 family
FMIBIEHO_00268 8.37e-129 - 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FMIBIEHO_00269 4.06e-125 - - - K - - - Bacterial regulatory proteins, tetR family
FMIBIEHO_00270 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_00271 1.69e-72 - - - S - - - FMN_bind
FMIBIEHO_00272 5.16e-83 - 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FMIBIEHO_00273 1.24e-165 - - - P - - - nitric oxide dioxygenase activity
FMIBIEHO_00274 8.92e-63 - - - S - - - Aminoacyl-tRNA editing domain
FMIBIEHO_00275 1.1e-209 - - - M ko:K02004 - ko00000,ko00002,ko02000 Membrane
FMIBIEHO_00276 2.83e-30 XK27_06785 - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
FMIBIEHO_00277 6.53e-133 - - - K - - - Transcriptional regulator
FMIBIEHO_00278 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FMIBIEHO_00279 4.13e-304 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
FMIBIEHO_00280 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
FMIBIEHO_00281 1.13e-20 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
FMIBIEHO_00282 4.36e-201 yneP - - L ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
FMIBIEHO_00283 3.35e-14 - - - S - - - NADPH-dependent FMN reductase
FMIBIEHO_00284 6.62e-13 - - - S - - - NADPH-dependent FMN reductase
FMIBIEHO_00285 4.06e-21 - - - S - - - NADPH-dependent FMN reductase
FMIBIEHO_00286 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
FMIBIEHO_00287 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FMIBIEHO_00288 7.29e-290 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00290 9.56e-196 - - - S ko:K07088 - ko00000 Membrane transport protein
FMIBIEHO_00291 5.57e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
FMIBIEHO_00292 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
FMIBIEHO_00293 1.2e-264 - - - EGP - - - Major Facilitator
FMIBIEHO_00294 1.81e-273 ycsG - - P - - - Natural resistance-associated macrophage protein
FMIBIEHO_00295 8.3e-172 - - - S ko:K07160 - ko00000 LamB/YcsF family
FMIBIEHO_00296 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
FMIBIEHO_00297 2.33e-89 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FMIBIEHO_00298 1.42e-244 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
FMIBIEHO_00299 5.16e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
FMIBIEHO_00300 2.31e-95 - - - K - - - helix_turn_helix, mercury resistance
FMIBIEHO_00301 4.35e-108 - - - S - - - Psort location Cytoplasmic, score
FMIBIEHO_00302 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
FMIBIEHO_00303 1.03e-123 - - - K - - - Acetyltransferase (GNAT) family
FMIBIEHO_00304 3.07e-135 - - - NU - - - mannosyl-glycoprotein
FMIBIEHO_00305 5.59e-250 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
FMIBIEHO_00306 1.27e-32 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
FMIBIEHO_00307 2.47e-273 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
FMIBIEHO_00308 1.62e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
FMIBIEHO_00309 8.11e-52 - - - S - - - Cytochrome B5
FMIBIEHO_00313 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
FMIBIEHO_00314 2.79e-125 - - - K - - - transcriptional regulator
FMIBIEHO_00315 1.57e-92 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
FMIBIEHO_00316 0.0 - - - L - - - Helicase C-terminal domain protein
FMIBIEHO_00317 5.37e-72 - - - S - - - MazG-like family
FMIBIEHO_00318 3.77e-139 - - - I - - - PAP2 superfamily
FMIBIEHO_00319 1.43e-251 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
FMIBIEHO_00320 1.28e-126 - - - - - - - -
FMIBIEHO_00321 2.97e-286 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
FMIBIEHO_00322 2.27e-218 - - - V - - - Beta-lactamase enzyme family
FMIBIEHO_00323 0.0 potE - - E - - - Amino Acid
FMIBIEHO_00325 2.74e-144 - - - - - - - -
FMIBIEHO_00326 2.72e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
FMIBIEHO_00327 1.71e-211 - - - K - - - LysR substrate binding domain
FMIBIEHO_00328 2.49e-80 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
FMIBIEHO_00329 5.67e-228 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
FMIBIEHO_00330 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
FMIBIEHO_00331 3.35e-249 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
FMIBIEHO_00332 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMIBIEHO_00333 1.87e-139 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FMIBIEHO_00334 5.36e-51 - - - I - - - alpha/beta hydrolase fold
FMIBIEHO_00335 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
FMIBIEHO_00336 0.0 nagZ 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolase family 3 N terminal domain
FMIBIEHO_00337 1.73e-97 - - - K - - - AraC-like ligand binding domain
FMIBIEHO_00338 7.92e-170 - - - EGP - - - Major Facilitator Superfamily
FMIBIEHO_00339 1.13e-214 - 3.2.1.37, 3.2.1.55 GH43,GH51 G ko:K01198,ko:K01209 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
FMIBIEHO_00340 6.83e-187 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
FMIBIEHO_00341 1.86e-260 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Domain of unknown function (DUF4982)
FMIBIEHO_00342 3.88e-64 nlhH_1 - - I ko:K01066 - ko00000,ko01000 acetylesterase activity
FMIBIEHO_00343 1.57e-197 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00344 1.23e-27 - - - L - - - Helix-turn-helix domain
FMIBIEHO_00345 4.5e-98 mleR - - K - - - LysR family
FMIBIEHO_00346 5.92e-287 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
FMIBIEHO_00347 1.43e-233 XK27_09615 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
FMIBIEHO_00348 1.01e-116 - - - S - - - NADPH-dependent FMN reductase
FMIBIEHO_00349 1.26e-280 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
FMIBIEHO_00350 2.61e-269 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
FMIBIEHO_00351 7.13e-288 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
FMIBIEHO_00352 9.16e-209 mleR2 - - K - - - LysR family transcriptional regulator
FMIBIEHO_00353 0.0 - - - S - - - Putative threonine/serine exporter
FMIBIEHO_00354 2.42e-155 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
FMIBIEHO_00355 1.92e-241 - - - I - - - Alpha beta
FMIBIEHO_00356 7.04e-139 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
FMIBIEHO_00357 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FMIBIEHO_00359 4.08e-215 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
FMIBIEHO_00360 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
FMIBIEHO_00361 3.85e-178 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
FMIBIEHO_00362 1.02e-260 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
FMIBIEHO_00363 1.57e-314 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
FMIBIEHO_00364 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
FMIBIEHO_00365 1.35e-149 - - - S - - - Domain of unknown function (DUF4811)
FMIBIEHO_00366 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
FMIBIEHO_00367 3.27e-95 - - - K - - - MerR HTH family regulatory protein
FMIBIEHO_00368 6.67e-77 - - - - - - - -
FMIBIEHO_00369 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FMIBIEHO_00370 2.66e-283 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
FMIBIEHO_00371 1.18e-28 elaA - - S ko:K02348 - ko00000 acyltransferase COG2153
FMIBIEHO_00372 2.49e-110 - - - T - - - Belongs to the universal stress protein A family
FMIBIEHO_00373 5.74e-143 - - - S - - - VIT family
FMIBIEHO_00374 9.24e-151 - - - S - - - membrane
FMIBIEHO_00375 3.58e-208 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
FMIBIEHO_00376 2.51e-158 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
FMIBIEHO_00377 1.26e-42 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
FMIBIEHO_00378 1.36e-161 - - - S - - - Putative threonine/serine exporter
FMIBIEHO_00379 8.17e-107 - - - S - - - Threonine/Serine exporter, ThrE
FMIBIEHO_00380 3.13e-149 - - - I - - - phosphatase
FMIBIEHO_00381 4.03e-198 - - - I - - - alpha/beta hydrolase fold
FMIBIEHO_00383 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
FMIBIEHO_00384 4.69e-151 dgk2 - - F - - - deoxynucleoside kinase
FMIBIEHO_00390 2.74e-14 fabG1 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMIBIEHO_00391 1.77e-58 - - - IQ - - - reductase
FMIBIEHO_00392 1.44e-190 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
FMIBIEHO_00393 5.67e-56 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
FMIBIEHO_00395 6.07e-154 - - - J - - - 2'-5' RNA ligase superfamily
FMIBIEHO_00396 1.69e-170 XK27_07210 - - S - - - B3 4 domain
FMIBIEHO_00397 1.37e-247 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
FMIBIEHO_00398 6.36e-103 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
FMIBIEHO_00399 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
FMIBIEHO_00400 2e-135 - - - K - - - Bacterial regulatory proteins, tetR family
FMIBIEHO_00401 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMIBIEHO_00402 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMIBIEHO_00403 2.92e-173 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
FMIBIEHO_00404 3.02e-275 - - - - - - - -
FMIBIEHO_00405 1.77e-40 pilD 3.4.23.43 - NOU ko:K02236,ko:K02506,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 aspartic-type endopeptidase activity
FMIBIEHO_00406 3.58e-93 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FMIBIEHO_00407 4.15e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
FMIBIEHO_00408 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FMIBIEHO_00409 3.14e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
FMIBIEHO_00410 5.89e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FMIBIEHO_00411 1.56e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
FMIBIEHO_00412 2.76e-60 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
FMIBIEHO_00413 3.32e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FMIBIEHO_00414 1.51e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FMIBIEHO_00415 2.63e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FMIBIEHO_00416 3.43e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FMIBIEHO_00417 2.78e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FMIBIEHO_00418 1.35e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
FMIBIEHO_00419 4.48e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FMIBIEHO_00420 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FMIBIEHO_00421 1.28e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FMIBIEHO_00422 1.75e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FMIBIEHO_00423 2.46e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FMIBIEHO_00424 7.64e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FMIBIEHO_00425 2.4e-120 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FMIBIEHO_00426 5.55e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FMIBIEHO_00427 3.59e-113 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FMIBIEHO_00428 6.96e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
FMIBIEHO_00429 3.5e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
FMIBIEHO_00430 2.24e-300 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
FMIBIEHO_00431 2.16e-156 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
FMIBIEHO_00432 1.69e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FMIBIEHO_00433 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
FMIBIEHO_00434 1.32e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FMIBIEHO_00435 8.02e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FMIBIEHO_00436 3.48e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FMIBIEHO_00437 1.02e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
FMIBIEHO_00438 6.12e-193 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FMIBIEHO_00439 2.06e-201 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FMIBIEHO_00440 2.37e-178 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
FMIBIEHO_00441 4.68e-187 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
FMIBIEHO_00442 5.57e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FMIBIEHO_00443 2.78e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
FMIBIEHO_00444 1.25e-264 - - - S - - - interspecies interaction between organisms
FMIBIEHO_00445 4.28e-178 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
FMIBIEHO_00446 2.33e-142 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
FMIBIEHO_00447 9.17e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
FMIBIEHO_00448 7.47e-280 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FMIBIEHO_00449 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
FMIBIEHO_00450 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FMIBIEHO_00451 1.94e-233 camS - - S - - - sex pheromone
FMIBIEHO_00452 9.93e-65 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FMIBIEHO_00453 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
FMIBIEHO_00454 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FMIBIEHO_00455 8.8e-238 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
FMIBIEHO_00456 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FMIBIEHO_00457 1.36e-65 - - - K - - - TRANSCRIPTIONal
FMIBIEHO_00458 1.59e-108 - - - K - - - Helix-turn-helix XRE-family like proteins
FMIBIEHO_00459 1.9e-111 - - - K - - - Psort location CytoplasmicMembrane, score
FMIBIEHO_00460 9.09e-149 - - - S ko:K07126 - ko00000 Sel1-like repeats.
FMIBIEHO_00461 1.01e-83 - - - S - - - YjbR
FMIBIEHO_00463 5.92e-157 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FMIBIEHO_00464 1.37e-138 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
FMIBIEHO_00465 9.21e-19 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
FMIBIEHO_00466 1.23e-29 - - - D ko:K19158 - ko00000,ko01000,ko02048 mRNA cleavage
FMIBIEHO_00467 1.06e-234 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
FMIBIEHO_00468 7.77e-127 - - - L - - - Transposase and inactivated derivatives, IS30 family
FMIBIEHO_00469 1.03e-73 - - - L - - - MULE transposase domain
FMIBIEHO_00470 2.18e-28 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00471 1.17e-182 - - - D - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00472 5.86e-109 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00473 1.8e-215 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_00474 1.68e-61 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_00475 2.38e-75 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00476 1.07e-247 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
FMIBIEHO_00478 2.29e-96 - 3.5.3.18 - E ko:K01482 - ko00000,ko01000,ko04147 Amidinotransferase
FMIBIEHO_00479 6.44e-115 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
FMIBIEHO_00480 0.0 sufI - - Q - - - Multicopper oxidase
FMIBIEHO_00481 1.28e-67 - - - K - - - 2 iron, 2 sulfur cluster binding
FMIBIEHO_00482 1.25e-26 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
FMIBIEHO_00483 8.01e-82 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
FMIBIEHO_00484 1.37e-151 - - - Q - - - Methyltransferase domain
FMIBIEHO_00486 9.54e-134 - - - S - - - CAAX protease self-immunity
FMIBIEHO_00487 1.52e-129 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FMIBIEHO_00488 6.79e-59 - - - EGP - - - Major Facilitator Superfamily
FMIBIEHO_00489 5.68e-81 - - - EGP - - - Major Facilitator Superfamily
FMIBIEHO_00490 2.39e-131 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMIBIEHO_00491 5.62e-276 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
FMIBIEHO_00492 2.2e-136 - - - - - - - -
FMIBIEHO_00493 4.16e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
FMIBIEHO_00494 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
FMIBIEHO_00495 2.89e-44 yneR - - S - - - Belongs to the HesB IscA family
FMIBIEHO_00496 4.1e-177 - - - S - - - NADPH-dependent FMN reductase
FMIBIEHO_00497 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
FMIBIEHO_00498 3.71e-205 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
FMIBIEHO_00499 1.8e-134 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
FMIBIEHO_00500 2.11e-82 - - - S - - - Domain of unknown function (DUF4828)
FMIBIEHO_00501 4.94e-244 mocA - - S - - - Oxidoreductase
FMIBIEHO_00502 1.42e-305 yfmL - - L - - - DEAD DEAH box helicase
FMIBIEHO_00504 1.38e-98 gtcA - - S - - - Teichoic acid glycosylation protein
FMIBIEHO_00505 9.59e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
FMIBIEHO_00506 4.08e-215 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
FMIBIEHO_00507 3.4e-171 XK27_08315 - - M - - - Sulfatase
FMIBIEHO_00508 1.97e-116 - - - L - - - MULE transposase domain
FMIBIEHO_00509 3.02e-61 - - - L - - - MULE transposase domain
FMIBIEHO_00510 0.0 XK27_08315 - - M - - - Sulfatase
FMIBIEHO_00511 1.01e-192 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
FMIBIEHO_00512 4.37e-43 - - - S - - - Protein of unknown function (DUF2922)
FMIBIEHO_00514 2.05e-188 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
FMIBIEHO_00515 1.73e-152 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
FMIBIEHO_00516 1.71e-191 cps1D - - M - - - Domain of unknown function (DUF4422)
FMIBIEHO_00517 7.97e-41 - - - M - - - biosynthesis protein
FMIBIEHO_00518 7.17e-84 - - - M - - - Domain of unknown function (DUF4422)
FMIBIEHO_00519 1.29e-83 - - - - - - - -
FMIBIEHO_00520 6.13e-107 - - - M - - - transferase activity, transferring glycosyl groups
FMIBIEHO_00521 1.11e-94 - - - M - - - Core-2/I-Branching enzyme
FMIBIEHO_00522 3.14e-277 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
FMIBIEHO_00523 3.75e-275 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
FMIBIEHO_00524 9.46e-87 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
FMIBIEHO_00525 1.28e-78 - - - S - - - enterobacterial common antigen metabolic process
FMIBIEHO_00526 1.84e-60 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
FMIBIEHO_00527 3.35e-105 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00528 1.31e-193 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00529 2.85e-68 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
FMIBIEHO_00530 4.14e-09 - - - - - - - -
FMIBIEHO_00531 6.59e-204 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
FMIBIEHO_00532 1.4e-217 yueF - - S - - - AI-2E family transporter
FMIBIEHO_00534 1.94e-316 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00535 6.18e-178 - - - L - - - PFAM Integrase catalytic region
FMIBIEHO_00536 4.66e-122 - - - S - - - Psort location CytoplasmicMembrane, score
FMIBIEHO_00537 2.47e-79 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FMIBIEHO_00538 1.5e-210 ykoT - - M - - - Glycosyl transferase family 2
FMIBIEHO_00539 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FMIBIEHO_00540 4.03e-30 - - - M - - - Glycosyltransferase, group 2 family protein
FMIBIEHO_00541 2.08e-82 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00542 3.23e-289 - - - L - - - MULE transposase domain
FMIBIEHO_00543 1.42e-113 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00544 5.64e-101 - - - S - - - Bacterial membrane protein, YfhO
FMIBIEHO_00545 6e-216 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
FMIBIEHO_00546 2.08e-84 - - - K - - - Transcriptional regulator, GntR family
FMIBIEHO_00547 5.71e-202 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_00550 1.38e-314 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
FMIBIEHO_00551 6.31e-208 - - - EG - - - EamA-like transporter family
FMIBIEHO_00552 5.78e-174 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FMIBIEHO_00553 9.48e-182 - - - G - - - MucBP domain
FMIBIEHO_00554 8.07e-126 - - - S - - - Pfam:DUF3816
FMIBIEHO_00555 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FMIBIEHO_00556 4.98e-142 pncA - - Q - - - Isochorismatase family
FMIBIEHO_00557 5.03e-166 - - - F - - - NUDIX domain
FMIBIEHO_00558 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
FMIBIEHO_00559 2.41e-07 - - - - - - - -
FMIBIEHO_00560 2.14e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
FMIBIEHO_00561 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FMIBIEHO_00562 1.88e-292 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
FMIBIEHO_00563 3.81e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
FMIBIEHO_00564 9.75e-232 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FMIBIEHO_00565 2.81e-53 - - - S - - - Protein of unknown function (DUF1797)
FMIBIEHO_00578 8.21e-07 - - - K - - - Transcriptional regulator
FMIBIEHO_00579 9.58e-19 ebrB - - U ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
FMIBIEHO_00580 3.37e-183 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
FMIBIEHO_00581 1.11e-145 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
FMIBIEHO_00582 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
FMIBIEHO_00583 2.99e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FMIBIEHO_00584 1.99e-204 - - - O - - - Uncharacterized protein family (UPF0051)
FMIBIEHO_00585 1.85e-301 - - - F ko:K03458 - ko00000 Permease
FMIBIEHO_00586 1.37e-252 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
FMIBIEHO_00587 4.4e-92 - - - M - - - LysM domain protein
FMIBIEHO_00588 3.6e-112 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
FMIBIEHO_00589 6.84e-103 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
FMIBIEHO_00590 9.96e-116 - - - K - - - Transcriptional regulator, TetR family
FMIBIEHO_00591 4.73e-85 - - - L - - - MULE transposase domain
FMIBIEHO_00592 3.02e-61 - - - L - - - MULE transposase domain
FMIBIEHO_00595 1.16e-303 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00596 3.32e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_00598 3.91e-31 - - - - - - - -
FMIBIEHO_00599 1.37e-315 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
FMIBIEHO_00600 3.59e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
FMIBIEHO_00601 0.0 - - - EGP - - - Major Facilitator
FMIBIEHO_00602 3.16e-125 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
FMIBIEHO_00603 1.14e-64 - - - - - - - -
FMIBIEHO_00604 3.78e-271 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FMIBIEHO_00605 1.87e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FMIBIEHO_00606 2.08e-284 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FMIBIEHO_00607 3.42e-162 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
FMIBIEHO_00608 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
FMIBIEHO_00609 9.88e-57 - - - - - - - -
FMIBIEHO_00610 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
FMIBIEHO_00611 4.71e-81 - - - S - - - Domain of unknown function DUF302
FMIBIEHO_00612 3.79e-195 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FMIBIEHO_00613 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
FMIBIEHO_00614 8.2e-113 - - - T - - - Belongs to the universal stress protein A family
FMIBIEHO_00615 0.0 - - - S - - - Putative peptidoglycan binding domain
FMIBIEHO_00616 2.3e-240 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FMIBIEHO_00617 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
FMIBIEHO_00618 1.21e-143 - - - - - - - -
FMIBIEHO_00619 6.39e-235 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
FMIBIEHO_00620 4.99e-153 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
FMIBIEHO_00621 9.96e-82 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FMIBIEHO_00622 6.44e-122 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
FMIBIEHO_00623 1.13e-133 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
FMIBIEHO_00624 4.09e-309 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
FMIBIEHO_00625 5.55e-137 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
FMIBIEHO_00626 7.33e-258 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
FMIBIEHO_00628 4.86e-53 - - - - - - - -
FMIBIEHO_00630 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
FMIBIEHO_00631 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
FMIBIEHO_00632 3.95e-73 yheA - - S - - - Belongs to the UPF0342 family
FMIBIEHO_00633 2.59e-230 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
FMIBIEHO_00634 6.67e-192 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
FMIBIEHO_00636 4.29e-101 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
FMIBIEHO_00637 3.68e-171 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_00638 1.55e-274 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
FMIBIEHO_00639 9.51e-161 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
FMIBIEHO_00640 6.83e-76 - - - S - - - Small secreted protein
FMIBIEHO_00641 1.53e-72 ytpP - - CO - - - Thioredoxin
FMIBIEHO_00642 1.11e-152 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FMIBIEHO_00643 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
FMIBIEHO_00644 1.24e-146 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
FMIBIEHO_00645 9.4e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
FMIBIEHO_00646 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FMIBIEHO_00647 3.08e-207 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
FMIBIEHO_00648 1.39e-135 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FMIBIEHO_00649 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FMIBIEHO_00650 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
FMIBIEHO_00651 2.66e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
FMIBIEHO_00652 6.95e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FMIBIEHO_00653 5.22e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
FMIBIEHO_00654 4.67e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FMIBIEHO_00655 2.58e-24 - - - S - - - Protein of unknown function (DUF1275)
FMIBIEHO_00656 7.57e-33 - - - S - - - Protein of unknown function (DUF1275)
FMIBIEHO_00657 6.88e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
FMIBIEHO_00658 6.57e-275 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
FMIBIEHO_00659 1.38e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
FMIBIEHO_00660 1.62e-120 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FMIBIEHO_00661 5.53e-145 yqeK - - H - - - Hydrolase, HD family
FMIBIEHO_00662 1.38e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
FMIBIEHO_00663 1.02e-179 yqeM - - Q - - - Methyltransferase
FMIBIEHO_00664 1.18e-273 ylbM - - S - - - Belongs to the UPF0348 family
FMIBIEHO_00665 4.81e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
FMIBIEHO_00666 7.89e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
FMIBIEHO_00667 1.38e-155 csrR - - K - - - response regulator
FMIBIEHO_00668 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
FMIBIEHO_00669 1.88e-298 - - - V - - - MatE
FMIBIEHO_00670 4.54e-91 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
FMIBIEHO_00671 4.58e-196 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FMIBIEHO_00672 8.13e-62 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
FMIBIEHO_00673 1.84e-180 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FMIBIEHO_00674 4.08e-117 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
FMIBIEHO_00675 1.44e-78 yodB - - K - - - Transcriptional regulator, HxlR family
FMIBIEHO_00676 4.45e-253 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FMIBIEHO_00677 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
FMIBIEHO_00678 1.69e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
FMIBIEHO_00679 1.81e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FMIBIEHO_00680 0.0 - - - S - - - membrane
FMIBIEHO_00681 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
FMIBIEHO_00682 7.58e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
FMIBIEHO_00683 3.66e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FMIBIEHO_00684 1.27e-147 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
FMIBIEHO_00685 1.14e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
FMIBIEHO_00686 2.23e-232 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
FMIBIEHO_00687 5.91e-93 yqhL - - P - - - Rhodanese-like protein
FMIBIEHO_00688 3.51e-33 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
FMIBIEHO_00689 6.29e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FMIBIEHO_00690 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
FMIBIEHO_00691 4.76e-19 - - - - - - - -
FMIBIEHO_00692 1.9e-201 - - - - - - - -
FMIBIEHO_00693 2.34e-226 - - - - - - - -
FMIBIEHO_00694 3.15e-120 - - - S - - - Protein conserved in bacteria
FMIBIEHO_00696 3.17e-149 - - - K - - - Transcriptional regulator
FMIBIEHO_00697 1.55e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
FMIBIEHO_00698 1.2e-70 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
FMIBIEHO_00699 8.74e-62 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
FMIBIEHO_00700 3.44e-262 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
FMIBIEHO_00701 2.1e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
FMIBIEHO_00702 9.82e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FMIBIEHO_00703 2e-206 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FMIBIEHO_00704 0.0 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FMIBIEHO_00705 1.64e-25 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
FMIBIEHO_00706 1.39e-200 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
FMIBIEHO_00707 1.14e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
FMIBIEHO_00708 9.93e-99 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
FMIBIEHO_00709 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
FMIBIEHO_00711 1.03e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
FMIBIEHO_00712 1.9e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
FMIBIEHO_00713 1.95e-273 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FMIBIEHO_00714 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FMIBIEHO_00715 3.25e-223 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FMIBIEHO_00716 5.57e-316 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FMIBIEHO_00717 1.68e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
FMIBIEHO_00718 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
FMIBIEHO_00719 9.22e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
FMIBIEHO_00720 1.1e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
FMIBIEHO_00721 3.05e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
FMIBIEHO_00722 5.82e-35 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
FMIBIEHO_00723 7.09e-76 yloU - - S - - - Asp23 family, cell envelope-related function
FMIBIEHO_00724 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
FMIBIEHO_00725 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FMIBIEHO_00726 2.2e-215 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
FMIBIEHO_00727 1.65e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
FMIBIEHO_00728 3.99e-166 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
FMIBIEHO_00729 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
FMIBIEHO_00730 9.65e-295 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FMIBIEHO_00731 1.72e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
FMIBIEHO_00732 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FMIBIEHO_00734 5.3e-48 - - - - - - - -
FMIBIEHO_00735 1.41e-40 - - - - - - - -
FMIBIEHO_00736 1.24e-170 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
FMIBIEHO_00737 1.15e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
FMIBIEHO_00738 1.95e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
FMIBIEHO_00739 8.27e-194 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
FMIBIEHO_00740 1.28e-176 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
FMIBIEHO_00741 2.78e-158 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
FMIBIEHO_00742 4.94e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
FMIBIEHO_00743 9.17e-54 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
FMIBIEHO_00744 1.52e-114 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FMIBIEHO_00745 2.22e-182 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
FMIBIEHO_00746 0.0 - - - E ko:K03294 - ko00000 Amino Acid
FMIBIEHO_00747 6.59e-76 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
FMIBIEHO_00748 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase cas3
FMIBIEHO_00749 6.25e-176 casA - - L ko:K19123 - ko00000,ko02048 the current gene model (or a revised gene model) may contain a frame shift
FMIBIEHO_00750 6.39e-51 - - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
FMIBIEHO_00751 1.56e-163 casC - - L ko:K19124 - ko00000,ko02048 CT1975-like protein
FMIBIEHO_00752 6.61e-81 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
FMIBIEHO_00753 9.63e-90 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
FMIBIEHO_00754 2.53e-159 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FMIBIEHO_00755 2.24e-97 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas2CT1978)
FMIBIEHO_00756 7.57e-195 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FMIBIEHO_00757 1.56e-73 ycsI - - S - - - Protein of unknown function (DUF1445)
FMIBIEHO_00758 1.62e-230 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
FMIBIEHO_00759 1.55e-310 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
FMIBIEHO_00760 1.03e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
FMIBIEHO_00761 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
FMIBIEHO_00762 1.12e-213 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
FMIBIEHO_00763 5.29e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
FMIBIEHO_00764 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
FMIBIEHO_00765 3.32e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_00766 4.24e-190 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00767 3.39e-120 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_00768 5.29e-263 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
FMIBIEHO_00769 1e-271 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
FMIBIEHO_00770 7.43e-231 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
FMIBIEHO_00771 5.33e-215 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
FMIBIEHO_00772 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
FMIBIEHO_00773 6.66e-115 ypmB - - S - - - Protein conserved in bacteria
FMIBIEHO_00774 1.73e-270 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
FMIBIEHO_00775 7.35e-42 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
FMIBIEHO_00776 4.14e-173 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
FMIBIEHO_00777 1.55e-189 ypuA - - S - - - Protein of unknown function (DUF1002)
FMIBIEHO_00778 1.65e-243 tas3 - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
FMIBIEHO_00779 6.64e-205 - - - EG - - - EamA-like transporter family
FMIBIEHO_00780 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
FMIBIEHO_00781 5.72e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
FMIBIEHO_00782 3.1e-144 ypsA - - S - - - Belongs to the UPF0398 family
FMIBIEHO_00783 2.08e-75 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
FMIBIEHO_00784 0.0 fusA1 - - J - - - elongation factor G
FMIBIEHO_00785 2.52e-270 - - - S ko:K06915 - ko00000 AAA-like domain
FMIBIEHO_00786 9.95e-108 - - - F - - - Hydrolase, NUDIX family
FMIBIEHO_00787 4.48e-279 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
FMIBIEHO_00788 1.03e-162 arcD - - S - - - C4-dicarboxylate anaerobic carrier
FMIBIEHO_00789 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
FMIBIEHO_00790 8.09e-05 - - - UW - - - Tetratricopeptide repeat
FMIBIEHO_00791 6.59e-69 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_00792 9.07e-133 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_00793 4.12e-61 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_00794 6.44e-22 - - - M - - - Glycosyltransferase like family 2
FMIBIEHO_00795 1.43e-153 yckA - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
FMIBIEHO_00796 8.4e-200 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
FMIBIEHO_00797 1.36e-139 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
FMIBIEHO_00798 3.77e-93 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
FMIBIEHO_00799 1e-91 esbA - - S - - - Family of unknown function (DUF5322)
FMIBIEHO_00800 1.27e-99 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FMIBIEHO_00801 2.57e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
FMIBIEHO_00802 1.2e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
FMIBIEHO_00803 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
FMIBIEHO_00804 4.36e-155 - 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
FMIBIEHO_00805 3.5e-221 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
FMIBIEHO_00806 7.67e-30 - - - S - - - Enoyl-(Acyl carrier protein) reductase
FMIBIEHO_00807 4.81e-275 - - - L - - - Transposase and inactivated derivatives, IS30 family
FMIBIEHO_00808 3.89e-75 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
FMIBIEHO_00809 2.51e-237 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
FMIBIEHO_00810 2.94e-97 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FMIBIEHO_00811 2.77e-290 - - - L - - - MULE transposase domain
FMIBIEHO_00812 3.18e-138 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_00813 0.0 FbpA - - K - - - Fibronectin-binding protein
FMIBIEHO_00814 6.96e-206 - - - S - - - EDD domain protein, DegV family
FMIBIEHO_00815 1.14e-128 - - - - - - - -
FMIBIEHO_00816 1.5e-173 yaaA - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
FMIBIEHO_00817 7.18e-153 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
FMIBIEHO_00818 1.24e-146 ylbE - - GM - - - NAD(P)H-binding
FMIBIEHO_00819 8.44e-128 - - - K - - - Acetyltransferase (GNAT) domain
FMIBIEHO_00820 4.69e-201 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
FMIBIEHO_00821 4.34e-299 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
FMIBIEHO_00822 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
FMIBIEHO_00823 5.69e-157 azlC - - E - - - azaleucine resistance protein AzlC
FMIBIEHO_00824 7.76e-72 azlD - - E - - - Branched-chain amino acid transport
FMIBIEHO_00825 8.01e-64 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00826 2.46e-73 - - - L - - - Helix-turn-helix domain
FMIBIEHO_00827 4.9e-232 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
FMIBIEHO_00828 7.41e-229 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
FMIBIEHO_00829 4.96e-275 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
FMIBIEHO_00830 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
FMIBIEHO_00831 2.03e-249 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
FMIBIEHO_00832 7.39e-276 - - - E - - - GDSL-like Lipase/Acylhydrolase family
FMIBIEHO_00833 8.37e-43 rlrB - - K - - - LysR substrate binding domain protein
FMIBIEHO_00834 7.1e-59 rlrB - - K - - - LysR substrate binding domain protein
FMIBIEHO_00835 1.04e-270 - - - EGP ko:K08196 - ko00000,ko02000 Major Facilitator
FMIBIEHO_00836 0.0 yhdP - - S - - - Transporter associated domain
FMIBIEHO_00837 1.8e-271 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
FMIBIEHO_00838 5.31e-201 - - - EGP ko:K18934 - ko00000,ko02000 Major Facilitator Superfamily
FMIBIEHO_00839 1.53e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
FMIBIEHO_00840 3.52e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FMIBIEHO_00841 2.02e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
FMIBIEHO_00842 2.25e-210 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
FMIBIEHO_00843 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
FMIBIEHO_00844 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
FMIBIEHO_00845 4.64e-36 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
FMIBIEHO_00846 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FMIBIEHO_00848 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
FMIBIEHO_00849 1.47e-66 - - - - - - - -
FMIBIEHO_00850 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
FMIBIEHO_00852 5.61e-301 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
FMIBIEHO_00853 2.32e-200 - - - S - - - Alpha beta hydrolase
FMIBIEHO_00854 9.35e-198 - - - GM - - - NAD(P)H-binding
FMIBIEHO_00855 2.24e-196 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
FMIBIEHO_00858 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
FMIBIEHO_00860 4.99e-273 - - - G - - - Major Facilitator Superfamily
FMIBIEHO_00861 7.56e-15 aroH 5.4.99.5 - E ko:K04516 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
FMIBIEHO_00862 4.62e-273 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FMIBIEHO_00863 2.7e-132 - - - - - - - -
FMIBIEHO_00864 1.36e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
FMIBIEHO_00865 1.18e-250 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
FMIBIEHO_00866 1.51e-116 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FMIBIEHO_00867 4.3e-277 aspB3 - - E - - - DegT/DnrJ/EryC1/StrS aminotransferase family
FMIBIEHO_00868 1.98e-234 - 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMIBIEHO_00869 2.2e-227 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
FMIBIEHO_00870 1.1e-201 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
FMIBIEHO_00871 3.6e-31 - - - S - - - Virus attachment protein p12 family
FMIBIEHO_00872 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
FMIBIEHO_00873 8.17e-45 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain
FMIBIEHO_00874 2.69e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
FMIBIEHO_00875 7.7e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
FMIBIEHO_00876 7.46e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FMIBIEHO_00877 2.5e-109 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
FMIBIEHO_00878 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
FMIBIEHO_00879 5.04e-237 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
FMIBIEHO_00880 9.64e-183 - - - EG - - - EamA-like transporter family
FMIBIEHO_00881 0.0 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
FMIBIEHO_00882 1.04e-26 - - - S - - - Domain of unknown function (DUF1858)
FMIBIEHO_00883 3.62e-72 yitW - - S - - - Iron-sulfur cluster assembly protein
FMIBIEHO_00884 5.4e-293 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
FMIBIEHO_00885 2.13e-182 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
FMIBIEHO_00886 3.59e-219 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FMIBIEHO_00887 7.91e-95 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
FMIBIEHO_00888 2.34e-47 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
FMIBIEHO_00889 4.09e-250 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FMIBIEHO_00890 2.31e-278 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Major Facilitator Superfamily
FMIBIEHO_00891 2.36e-77 - - - S - - - Iron-sulfur cluster assembly protein
FMIBIEHO_00892 1.65e-210 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
FMIBIEHO_00893 8.72e-173 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
FMIBIEHO_00895 3.49e-217 - - - H - - - geranyltranstransferase activity
FMIBIEHO_00896 2.07e-236 - - - - - - - -
FMIBIEHO_00897 1.99e-53 - - - - - - - -
FMIBIEHO_00898 1.83e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
FMIBIEHO_00899 5.67e-240 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
FMIBIEHO_00900 8.62e-102 nreA - - T ko:K10851 ko02020,map02020 ko00000,ko00001 GAF domain
FMIBIEHO_00901 6.94e-54 - - - - - - - -
FMIBIEHO_00902 7.14e-128 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
FMIBIEHO_00903 5.5e-108 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
FMIBIEHO_00904 3.66e-294 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
FMIBIEHO_00905 2.18e-112 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
FMIBIEHO_00906 1.47e-242 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
FMIBIEHO_00907 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FMIBIEHO_00908 0.0 - 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
FMIBIEHO_00909 8.77e-132 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 Nitrate reductase delta subunit
FMIBIEHO_00910 3.17e-166 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
FMIBIEHO_00911 3.71e-236 - - - - - - - -
FMIBIEHO_00912 1.01e-99 - - - - - - - -
FMIBIEHO_00913 3.79e-83 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
FMIBIEHO_00914 4.51e-61 - - - S ko:K07118 - ko00000 NAD(P)H-binding
FMIBIEHO_00915 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
FMIBIEHO_00916 1.69e-124 - - - V - - - VanZ like family
FMIBIEHO_00917 1.71e-283 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
FMIBIEHO_00918 2.74e-81 - - - - - - - -
FMIBIEHO_00919 1.19e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
FMIBIEHO_00920 2.34e-301 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
FMIBIEHO_00921 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
FMIBIEHO_00922 1.5e-135 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
FMIBIEHO_00923 4.17e-64 - - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Transcriptional activator, Rgg GadR MutR family
FMIBIEHO_00925 1.48e-61 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 ATPase, P-type transporting, HAD superfamily, subfamily IC
FMIBIEHO_00927 2.95e-106 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
FMIBIEHO_00928 3.92e-55 - - - - - - - -
FMIBIEHO_00929 2.46e-217 - - - GK - - - ROK family
FMIBIEHO_00930 1.23e-165 - - - C - - - Oxidoreductase NAD-binding domain
FMIBIEHO_00931 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
FMIBIEHO_00932 6.33e-133 - - - K - - - Acetyltransferase (GNAT) family
FMIBIEHO_00933 9.85e-88 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
FMIBIEHO_00934 1.73e-72 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FMIBIEHO_00935 2.58e-71 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FMIBIEHO_00938 1.55e-66 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00939 3.38e-301 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
FMIBIEHO_00940 4.94e-91 treR - - K ko:K03486 - ko00000,ko03000 UTRA
FMIBIEHO_00941 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
FMIBIEHO_00942 1.39e-93 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
FMIBIEHO_00943 3.8e-31 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
FMIBIEHO_00944 6.26e-215 - - - L - - - PFAM Integrase catalytic region
FMIBIEHO_00945 5.28e-132 - - - K - - - DNA-templated transcription, initiation
FMIBIEHO_00947 0.0 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
FMIBIEHO_00948 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
FMIBIEHO_00949 6.4e-149 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_00950 3.1e-170 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
FMIBIEHO_00951 4.92e-115 rmeB - - K - - - transcriptional regulator, MerR family
FMIBIEHO_00952 7.93e-55 yrfB - - C - - - NADH:flavin oxidoreductase / NADH oxidase family
FMIBIEHO_00953 1.41e-146 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
FMIBIEHO_00954 8.98e-73 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
FMIBIEHO_00956 2.4e-277 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
FMIBIEHO_00957 0.0 guaD 3.5.4.3 - F ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Amidohydrolase family
FMIBIEHO_00958 2.06e-47 tdh 1.1.1.14 - C ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
FMIBIEHO_00959 4.66e-121 - - - E - - - Zinc-binding dehydrogenase
FMIBIEHO_00960 5.61e-41 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
FMIBIEHO_00961 2.42e-43 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
FMIBIEHO_00962 7.2e-161 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
FMIBIEHO_00963 1.72e-13 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
FMIBIEHO_00964 3.62e-271 gadB 4.1.1.15, 4.1.2.27 - E ko:K01580,ko:K01634 ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940 ko00000,ko00001,ko00002,ko01000 Belongs to the group II decarboxylase family
FMIBIEHO_00966 4.72e-141 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_00967 2.91e-26 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_00968 1.48e-49 - - - L - - - Bacterial dnaA protein
FMIBIEHO_00969 0.0 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00970 7.62e-176 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00971 3.9e-230 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00972 7.97e-152 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00973 2.27e-302 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FMIBIEHO_00974 8.8e-82 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
FMIBIEHO_00975 1.22e-163 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_00976 2.73e-284 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
FMIBIEHO_00977 5.47e-197 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
FMIBIEHO_00978 8.93e-185 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
FMIBIEHO_00980 8.99e-278 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
FMIBIEHO_00982 1.59e-80 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
FMIBIEHO_00983 4.72e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_00984 5.5e-91 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_00985 8.73e-129 - - - K - - - Virulence activator alpha C-term
FMIBIEHO_00986 3.37e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
FMIBIEHO_00987 6.12e-33 - - - S - - - SNARE associated Golgi protein
FMIBIEHO_00988 6.02e-17 - - - S - - - SNARE associated Golgi protein
FMIBIEHO_00989 3.88e-304 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
FMIBIEHO_00990 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FMIBIEHO_00992 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
FMIBIEHO_00994 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
FMIBIEHO_00995 3.89e-209 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
FMIBIEHO_00996 7.01e-212 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
FMIBIEHO_00997 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FMIBIEHO_00998 3.06e-206 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
FMIBIEHO_01000 1.95e-291 - - - - - - - -
FMIBIEHO_01001 2.37e-249 flp - - V - - - Beta-lactamase
FMIBIEHO_01002 8.23e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
FMIBIEHO_01003 2.96e-159 - - - S ko:K07090 - ko00000 membrane transporter protein
FMIBIEHO_01004 3.82e-238 XK27_12525 - - S - - - AI-2E family transporter
FMIBIEHO_01005 1.33e-273 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
FMIBIEHO_01006 8.16e-206 rssA - - S - - - Phospholipase, patatin family
FMIBIEHO_01007 6.5e-144 - - - K - - - LysR substrate binding domain
FMIBIEHO_01008 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
FMIBIEHO_01009 7.21e-108 - - - S - - - Domain of unknown function (DUF4352)
FMIBIEHO_01010 7.06e-145 yicL - - EG - - - EamA-like transporter family
FMIBIEHO_01011 3.76e-84 - - - - - - - -
FMIBIEHO_01014 2.97e-41 - - - - - - - -
FMIBIEHO_01015 3.96e-89 - - - S - - - pyridoxamine 5-phosphate
FMIBIEHO_01016 5.37e-230 - - - K - - - WYL domain
FMIBIEHO_01017 3.14e-310 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
FMIBIEHO_01018 1.65e-53 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
FMIBIEHO_01019 2.86e-215 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
FMIBIEHO_01020 2.77e-270 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FMIBIEHO_01021 5.98e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_01022 1.92e-302 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01023 3.7e-219 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
FMIBIEHO_01024 1.27e-25 adh 1.1.1.1 - C ko:K00001,ko:K18369 ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
FMIBIEHO_01025 4.32e-278 - - - G - - - Transporter, major facilitator family protein
FMIBIEHO_01026 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
FMIBIEHO_01027 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FMIBIEHO_01028 2.23e-73 yuxO - - Q - - - Thioesterase superfamily
FMIBIEHO_01029 6.51e-45 - - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
FMIBIEHO_01030 8.12e-77 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FMIBIEHO_01031 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FMIBIEHO_01032 1.33e-205 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
FMIBIEHO_01033 1.2e-09 - - - C - - - Domain of unknown function (DUF4145)
FMIBIEHO_01034 2.37e-291 - - - L - - - MULE transposase domain
FMIBIEHO_01035 1.45e-155 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FMIBIEHO_01036 1.14e-184 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FMIBIEHO_01037 6.46e-120 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
FMIBIEHO_01038 7.73e-13 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
FMIBIEHO_01039 9.68e-67 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
FMIBIEHO_01040 5.38e-138 - - - GK - - - ROK family
FMIBIEHO_01041 3e-232 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
FMIBIEHO_01042 6.08e-17 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
FMIBIEHO_01043 1.91e-21 ISPlu1B - - L ko:K07482 - ko00000 IS30 family
FMIBIEHO_01044 5.38e-272 - - - L - - - Transposase and inactivated derivatives, IS30 family
FMIBIEHO_01045 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
FMIBIEHO_01046 1.72e-36 XK27_02560 - - S - - - Pfam:DUF59
FMIBIEHO_01047 2.84e-167 yocS - - S ko:K03453 - ko00000 Transporter
FMIBIEHO_01048 1.79e-304 - - - EGP ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
FMIBIEHO_01049 1.05e-251 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
FMIBIEHO_01050 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FMIBIEHO_01051 6.27e-142 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FMIBIEHO_01052 2.61e-188 XK27_00020 - - J - - - Telomere recombination
FMIBIEHO_01054 1.46e-78 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
FMIBIEHO_01055 0.000602 - - - G - - - COG2513 PEP phosphonomutase and related enzymes
FMIBIEHO_01056 3.07e-20 - - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
FMIBIEHO_01057 5.89e-106 - - - G ko:K08368,ko:K08369 - ko00000,ko02000 Major Facilitator
FMIBIEHO_01058 9.66e-07 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
FMIBIEHO_01059 1.6e-71 - - - S - - - Enoyl-(Acyl carrier protein) reductase
FMIBIEHO_01060 1.66e-38 - - - IQ - - - oxidoreductase activity
FMIBIEHO_01061 4e-67 - - - C - - - Flavodoxin
FMIBIEHO_01062 1.05e-64 yicL - - EG - - - EamA-like transporter family
FMIBIEHO_01063 4.05e-99 yicL - - EG - - - EamA-like transporter family
FMIBIEHO_01064 3.77e-139 - - - L - - - Integrase
FMIBIEHO_01065 2.63e-58 - - - K - - - transcriptional regulator
FMIBIEHO_01066 2.01e-146 - - - GM - - - NmrA-like family
FMIBIEHO_01067 2.57e-20 - - - C - - - Flavodoxin
FMIBIEHO_01068 2.64e-95 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
FMIBIEHO_01069 5.23e-97 - - - O ko:K07397 - ko00000 OsmC-like protein
FMIBIEHO_01070 7.28e-101 ywnA - - K - - - Transcriptional regulator
FMIBIEHO_01071 1.16e-208 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
FMIBIEHO_01072 6.29e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
FMIBIEHO_01073 1.9e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_01074 4.6e-131 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
FMIBIEHO_01075 1.39e-191 - - - C - - - Zinc-binding dehydrogenase
FMIBIEHO_01076 8.27e-250 bdhA 1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4 - C ko:K00004,ko:K00008,ko:K00098 ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Zinc-binding dehydrogenase
FMIBIEHO_01077 1.72e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
FMIBIEHO_01078 9.77e-230 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
FMIBIEHO_01079 1.77e-260 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
FMIBIEHO_01080 1.08e-78 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
FMIBIEHO_01081 7.47e-229 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
FMIBIEHO_01082 7.88e-46 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate/isopropylmalate dehydrogenase
FMIBIEHO_01083 1.06e-192 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
FMIBIEHO_01084 1.85e-105 - - - S - - - ECF-type riboflavin transporter, S component
FMIBIEHO_01085 8.37e-216 yvgN - - C - - - Aldo keto reductase
FMIBIEHO_01086 1.24e-207 - - - S - - - DUF218 domain
FMIBIEHO_01088 3.31e-125 - 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
FMIBIEHO_01089 1.82e-209 - - - I - - - alpha/beta hydrolase fold
FMIBIEHO_01090 2.19e-79 - - - S - - - Phage minor capsid protein 2
FMIBIEHO_01091 2.64e-45 - - - S - - - Phage minor capsid protein 2
FMIBIEHO_01094 4.61e-70 - - - E - - - Aminotransferase
FMIBIEHO_01095 1.46e-121 - - - E - - - Aminotransferase
FMIBIEHO_01096 5.35e-25 - - - E - - - Aminotransferase
FMIBIEHO_01097 8.48e-231 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
FMIBIEHO_01098 2.72e-316 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
FMIBIEHO_01099 1.32e-125 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Phosphoribosyl transferase domain
FMIBIEHO_01100 5.75e-120 - - - S - - - Fic/DOC family
FMIBIEHO_01101 2.59e-45 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
FMIBIEHO_01102 2.19e-09 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
FMIBIEHO_01103 1.49e-138 lacA 2.3.1.18, 2.3.1.79 - S ko:K00633,ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
FMIBIEHO_01104 5.43e-256 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
FMIBIEHO_01105 0.0 - - - E ko:K03758 - ko00000,ko02000 Amino acid permease
FMIBIEHO_01106 1.38e-151 - - - M - - - racemase activity, acting on amino acids and derivatives
FMIBIEHO_01107 9.08e-197 - - - C - - - NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
FMIBIEHO_01108 1.1e-33 eriC - - P ko:K03281 - ko00000 chloride
FMIBIEHO_01109 1.13e-82 eriC - - P ko:K03281 - ko00000 chloride
FMIBIEHO_01110 2.2e-20 ycnB - - U - - - Belongs to the major facilitator superfamily
FMIBIEHO_01111 6.37e-314 yhjX - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
FMIBIEHO_01112 3.39e-155 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
FMIBIEHO_01113 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
FMIBIEHO_01115 0.0 - - - EP - - - Psort location Cytoplasmic, score
FMIBIEHO_01116 3.75e-307 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
FMIBIEHO_01117 2.4e-312 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
FMIBIEHO_01118 1.64e-105 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
FMIBIEHO_01119 3.6e-122 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
FMIBIEHO_01120 4.65e-100 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
FMIBIEHO_01121 7.86e-92 - - - S - - - Belongs to the HesB IscA family
FMIBIEHO_01122 4.6e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
FMIBIEHO_01123 2.53e-123 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
FMIBIEHO_01124 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FMIBIEHO_01125 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
FMIBIEHO_01126 2.14e-133 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
FMIBIEHO_01127 9.3e-220 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
FMIBIEHO_01128 2.24e-198 - - - D - - - DNA integration
FMIBIEHO_01129 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FMIBIEHO_01130 5.14e-212 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
FMIBIEHO_01131 8.69e-182 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FMIBIEHO_01132 1.03e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FMIBIEHO_01133 1.21e-48 yozE - - S - - - Belongs to the UPF0346 family
FMIBIEHO_01134 1.16e-134 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
FMIBIEHO_01135 2.46e-217 - - - E - - - lipolytic protein G-D-S-L family
FMIBIEHO_01136 9.86e-146 cat 2.3.1.79 - S ko:K00661,ko:K18234 - ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
FMIBIEHO_01137 2.06e-278 - 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
FMIBIEHO_01138 3.85e-197 WQ51_01275 - - S - - - EDD domain protein, DegV family
FMIBIEHO_01139 8.06e-141 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
FMIBIEHO_01140 4.4e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FMIBIEHO_01141 5.32e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FMIBIEHO_01142 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_01143 7.55e-285 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FMIBIEHO_01144 2.02e-211 - - - L - - - Phage integrase, N-terminal SAM-like domain
FMIBIEHO_01145 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01146 2.52e-300 XK27_05225 - - S - - - Tetratricopeptide repeat protein
FMIBIEHO_01147 2.65e-53 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
FMIBIEHO_01148 1.29e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
FMIBIEHO_01149 4.63e-275 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
FMIBIEHO_01150 5.63e-154 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
FMIBIEHO_01151 3.58e-75 - - - M - - - Lysin motif
FMIBIEHO_01152 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
FMIBIEHO_01153 3.83e-254 - - - S - - - Helix-turn-helix domain
FMIBIEHO_01154 2.03e-112 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
FMIBIEHO_01155 1.44e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
FMIBIEHO_01156 3.2e-131 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FMIBIEHO_01157 1.18e-182 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FMIBIEHO_01158 2.23e-89 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
FMIBIEHO_01159 1.84e-185 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
FMIBIEHO_01160 6.26e-215 yitL - - S ko:K00243 - ko00000 S1 domain
FMIBIEHO_01161 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
FMIBIEHO_01162 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
FMIBIEHO_01164 1.07e-302 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
FMIBIEHO_01165 6.96e-201 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FMIBIEHO_01166 1.38e-162 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
FMIBIEHO_01167 5.64e-153 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
FMIBIEHO_01168 3.38e-293 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
FMIBIEHO_01169 5.2e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FMIBIEHO_01170 9.79e-278 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FMIBIEHO_01171 5.43e-182 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
FMIBIEHO_01172 1.09e-223 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FMIBIEHO_01173 4.67e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
FMIBIEHO_01174 1.29e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
FMIBIEHO_01175 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
FMIBIEHO_01176 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
FMIBIEHO_01177 5.25e-234 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FMIBIEHO_01178 4.95e-216 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
FMIBIEHO_01179 0.0 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01180 4.74e-23 - - - - - - - -
FMIBIEHO_01181 1.19e-41 - - - S - - - Transglycosylase associated protein
FMIBIEHO_01182 3.37e-96 asp1 - - S - - - Asp23 family, cell envelope-related function
FMIBIEHO_01183 1.3e-112 - - - - - - - -
FMIBIEHO_01184 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
FMIBIEHO_01185 2.83e-199 is18 - - L - - - COG2801 Transposase and inactivated derivatives
FMIBIEHO_01186 1.21e-264 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
FMIBIEHO_01187 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
FMIBIEHO_01188 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
FMIBIEHO_01189 3.59e-240 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
FMIBIEHO_01190 1.85e-200 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
FMIBIEHO_01191 8.91e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FMIBIEHO_01192 1.54e-87 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
FMIBIEHO_01193 8.34e-104 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FMIBIEHO_01194 3.02e-229 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
FMIBIEHO_01195 1.52e-93 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
FMIBIEHO_01196 3.81e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
FMIBIEHO_01197 1.1e-165 - - - F - - - glutamine amidotransferase
FMIBIEHO_01198 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
FMIBIEHO_01199 1.39e-314 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
FMIBIEHO_01200 4.43e-250 - 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
FMIBIEHO_01201 3.81e-227 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Ami_3
FMIBIEHO_01202 3.92e-217 - - - G - - - Phosphotransferase enzyme family
FMIBIEHO_01203 1.18e-222 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
FMIBIEHO_01204 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
FMIBIEHO_01205 6.72e-204 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
FMIBIEHO_01206 4.08e-271 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Homoserine dehydrogenase
FMIBIEHO_01208 5.44e-176 - - - IQ - - - KR domain
FMIBIEHO_01209 5.25e-197 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
FMIBIEHO_01210 1.19e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_01211 2.78e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
FMIBIEHO_01212 2.79e-146 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
FMIBIEHO_01214 8.63e-108 - - - S - - - MmgE/PrpD family
FMIBIEHO_01215 1.47e-214 - 4.3.2.2, 5.5.1.2 - F ko:K01756,ko:K01857 ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko00002,ko01000 Adenylosuccinate lyase C-terminus
FMIBIEHO_01216 2.43e-184 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 Peptidase dimerisation domain
FMIBIEHO_01217 2.15e-100 yxeO - - E ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
FMIBIEHO_01218 1.47e-99 yxeN - - U ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
FMIBIEHO_01219 1.46e-59 yxeL - - K - - - acetyltransferase
FMIBIEHO_01220 3.6e-77 yxeM - - ET ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
FMIBIEHO_01222 4.6e-271 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Cys/Met metabolism PLP-dependent enzyme
FMIBIEHO_01223 1.98e-279 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
FMIBIEHO_01224 1.23e-109 - - - K - - - Transcriptional regulator
FMIBIEHO_01225 3.12e-100 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
FMIBIEHO_01226 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FMIBIEHO_01227 1.21e-75 - - - - - - - -
FMIBIEHO_01228 1.05e-174 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
FMIBIEHO_01229 9.06e-232 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
FMIBIEHO_01230 4.82e-72 - - - - - - - -
FMIBIEHO_01232 5.81e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
FMIBIEHO_01233 1.34e-51 - - - S - - - integral membrane protein
FMIBIEHO_01234 1.08e-53 - - - S - - - integral membrane protein
FMIBIEHO_01235 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FMIBIEHO_01236 3.4e-178 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FMIBIEHO_01237 9e-184 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
FMIBIEHO_01239 2.14e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
FMIBIEHO_01240 6.81e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
FMIBIEHO_01241 2.09e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
FMIBIEHO_01242 1.66e-51 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
FMIBIEHO_01243 2.49e-270 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
FMIBIEHO_01244 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
FMIBIEHO_01245 8.45e-97 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
FMIBIEHO_01246 6.66e-135 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
FMIBIEHO_01247 3.76e-05 - - - K - - - LysR substrate binding domain
FMIBIEHO_01248 2.62e-126 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FMIBIEHO_01249 1.03e-202 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
FMIBIEHO_01250 5.05e-136 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FMIBIEHO_01251 1.55e-151 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
FMIBIEHO_01252 3.82e-133 cadD - - P - - - Cadmium resistance transporter
FMIBIEHO_01253 4.7e-280 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01254 2.09e-23 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_01255 5.77e-72 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_01257 9.49e-283 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
FMIBIEHO_01258 6.45e-20 - - - S - - - ABC-type transport system involved in multi-copper enzyme maturation permease component
FMIBIEHO_01259 2.06e-66 - - - T - - - Transcriptional regulatory protein, C terminal
FMIBIEHO_01260 4.66e-76 - - - T - - - His Kinase A (phosphoacceptor) domain
FMIBIEHO_01261 1.73e-71 - - - C - - - FMN binding
FMIBIEHO_01262 1.98e-258 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FMIBIEHO_01263 1.84e-138 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
FMIBIEHO_01264 7.59e-288 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
FMIBIEHO_01265 1.14e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
FMIBIEHO_01266 9.59e-104 - - - K - - - 2 iron, 2 sulfur cluster binding
FMIBIEHO_01267 0.0 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
FMIBIEHO_01268 8.79e-284 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMIBIEHO_01269 4.15e-258 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FMIBIEHO_01270 1.48e-105 - - - C - - - aldo keto reductase
FMIBIEHO_01271 1.65e-22 - - - C - - - aldo keto reductase
FMIBIEHO_01272 3.72e-145 pgm1 - - G - - - phosphoglycerate mutase
FMIBIEHO_01274 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
FMIBIEHO_01275 1.56e-255 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FMIBIEHO_01276 1.52e-68 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
FMIBIEHO_01277 4.55e-74 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FMIBIEHO_01278 5.43e-183 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FMIBIEHO_01279 3.25e-165 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FMIBIEHO_01280 1.21e-143 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FMIBIEHO_01281 5.12e-132 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
FMIBIEHO_01282 2.12e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FMIBIEHO_01283 3.18e-140 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
FMIBIEHO_01284 8.68e-277 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FMIBIEHO_01285 2.55e-215 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphate phosphatase, HisJ
FMIBIEHO_01286 3.33e-63 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FMIBIEHO_01287 5.21e-11 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
FMIBIEHO_01288 1.12e-123 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FMIBIEHO_01289 9.95e-267 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
FMIBIEHO_01290 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
FMIBIEHO_01291 6.54e-85 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FMIBIEHO_01292 1.21e-244 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
FMIBIEHO_01293 3.87e-80 - - - - - - - -
FMIBIEHO_01294 4.07e-214 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01295 4.7e-42 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01296 4.79e-291 - - - L - - - MULE transposase domain
FMIBIEHO_01297 1.68e-61 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01299 1.14e-121 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01300 3.68e-176 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
FMIBIEHO_01301 1.95e-290 - - - L - - - MULE transposase domain
FMIBIEHO_01302 1.24e-130 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
FMIBIEHO_01303 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
FMIBIEHO_01304 4.95e-123 ybcH - - D ko:K06889 - ko00000 Alpha beta
FMIBIEHO_01305 1.02e-69 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
FMIBIEHO_01306 7.82e-240 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FMIBIEHO_01307 1e-34 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_01309 2.17e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
FMIBIEHO_01311 1.37e-196 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
FMIBIEHO_01312 8.97e-227 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
FMIBIEHO_01313 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
FMIBIEHO_01314 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
FMIBIEHO_01315 1.7e-151 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01316 2.73e-36 - - - L - - - Helix-turn-helix domain
FMIBIEHO_01317 2.7e-316 - - - U - - - Belongs to the major facilitator superfamily
FMIBIEHO_01318 2.15e-235 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
FMIBIEHO_01319 3.22e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FMIBIEHO_01320 1.49e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FMIBIEHO_01321 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FMIBIEHO_01322 5.5e-67 ylxQ - - J - - - ribosomal protein
FMIBIEHO_01323 3.71e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
FMIBIEHO_01324 6.7e-283 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
FMIBIEHO_01325 8.99e-109 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
FMIBIEHO_01326 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
FMIBIEHO_01327 4.36e-264 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
FMIBIEHO_01328 1.43e-250 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FMIBIEHO_01329 2.87e-263 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FMIBIEHO_01330 1.19e-175 argB 2.7.2.8 - F ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
FMIBIEHO_01331 1.09e-273 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine
FMIBIEHO_01332 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FMIBIEHO_01333 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
FMIBIEHO_01334 8.02e-294 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
FMIBIEHO_01335 1.17e-173 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
FMIBIEHO_01336 7.73e-185 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FMIBIEHO_01337 6.51e-122 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
FMIBIEHO_01338 1.38e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
FMIBIEHO_01339 1.19e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FMIBIEHO_01340 5.21e-180 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
FMIBIEHO_01341 7.65e-62 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
FMIBIEHO_01342 6.86e-176 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
FMIBIEHO_01343 3.06e-150 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
FMIBIEHO_01344 1.05e-36 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
FMIBIEHO_01345 1.97e-49 ynzC - - S - - - UPF0291 protein
FMIBIEHO_01346 4.36e-149 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FMIBIEHO_01347 9.01e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
FMIBIEHO_01348 4.31e-151 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
FMIBIEHO_01349 3.4e-304 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
FMIBIEHO_01350 2.76e-110 lutC - - S ko:K00782 - ko00000 LUD domain
FMIBIEHO_01351 1.79e-37 - - - M - - - LPXTG-motif cell wall anchor domain protein
FMIBIEHO_01352 3.13e-67 - - - M - - - LPXTG-motif cell wall anchor domain protein
FMIBIEHO_01353 1.27e-46 - - - M - - - domain protein
FMIBIEHO_01354 1.99e-11 - - - Q - - - Signal peptide protein, YSIRK family
FMIBIEHO_01355 1.23e-34 yitW - - S - - - DNA methyltransferase
FMIBIEHO_01356 4.39e-141 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
FMIBIEHO_01357 1.41e-83 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
FMIBIEHO_01360 1.98e-162 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01361 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
FMIBIEHO_01362 0.0 - - - G - - - Major Facilitator Superfamily
FMIBIEHO_01363 9.07e-168 tnp1216 - - L ko:K07498 - ko00000 DDE domain
FMIBIEHO_01364 1.64e-299 yagE - - E - - - Amino acid permease
FMIBIEHO_01365 1.98e-279 - - - S - - - Domain of unknown function (DUF389)
FMIBIEHO_01366 1.58e-70 - - - - - - - -
FMIBIEHO_01367 1.94e-86 - - - - - - - -
FMIBIEHO_01368 2.2e-66 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FMIBIEHO_01369 9.29e-138 - - - K - - - Bacterial regulatory proteins, tetR family
FMIBIEHO_01370 9.32e-223 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_01372 1.72e-52 - - - L - - - MULE transposase domain
FMIBIEHO_01373 7.47e-216 - - - L - - - MULE transposase domain
FMIBIEHO_01374 0.0 ybeC - - E - - - amino acid
FMIBIEHO_01375 9.66e-94 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FMIBIEHO_01376 1.28e-85 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FMIBIEHO_01377 4.82e-149 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01378 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01379 2.37e-119 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01381 1.18e-60 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01383 0.000243 - - - K - - - transcriptional regulator
FMIBIEHO_01384 2.24e-27 - - - S - - - Protein of unknown function with HXXEE motif
FMIBIEHO_01385 6.94e-200 is18 - - L - - - COG2801 Transposase and inactivated derivatives
FMIBIEHO_01386 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
FMIBIEHO_01388 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01389 1.27e-217 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01390 1.34e-131 - - - L - - - MULE transposase domain
FMIBIEHO_01391 6.07e-142 - - - L - - - MULE transposase domain
FMIBIEHO_01392 3.05e-57 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_01393 2.9e-61 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01395 7.52e-94 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01396 2.51e-45 - - - - - - - -
FMIBIEHO_01397 3.85e-198 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01398 3.68e-75 - - - L - - - Helix-turn-helix domain
FMIBIEHO_01399 5.55e-98 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01400 8.29e-94 - - - L - - - MULE transposase domain
FMIBIEHO_01401 3.02e-61 - - - L - - - MULE transposase domain
FMIBIEHO_01402 2.01e-158 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01403 4.21e-77 - - - S - - - Protein of unknown function (DUF1722)
FMIBIEHO_01404 2.07e-201 is18 - - L - - - Integrase core domain
FMIBIEHO_01405 5.82e-188 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
FMIBIEHO_01406 2.81e-198 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
FMIBIEHO_01407 1.98e-280 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FMIBIEHO_01408 9.76e-108 - - - L - - - PFAM Integrase catalytic region
FMIBIEHO_01409 1.27e-39 - - - L - - - PFAM Integrase catalytic region
FMIBIEHO_01410 4.22e-74 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01411 2.43e-98 - - - S - - - Short repeat of unknown function (DUF308)
FMIBIEHO_01412 5.15e-247 - - - L - - - Transposase and inactivated derivatives, IS30 family
FMIBIEHO_01413 4.39e-133 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FMIBIEHO_01414 8.83e-17 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01415 1.96e-58 - - - L - - - MULE transposase domain
FMIBIEHO_01416 1.18e-94 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01417 5.23e-75 - - - L - - - Helix-turn-helix domain
FMIBIEHO_01418 6.52e-216 - - - L - - - MULE transposase domain
FMIBIEHO_01419 1.64e-32 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
FMIBIEHO_01420 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
FMIBIEHO_01422 1.45e-309 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
FMIBIEHO_01423 6.94e-200 is18 - - L - - - COG2801 Transposase and inactivated derivatives
FMIBIEHO_01424 2.48e-52 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
FMIBIEHO_01425 4.7e-42 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01427 1.14e-121 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_01428 1.91e-87 - - - - - - - -
FMIBIEHO_01429 2.99e-160 tnp1216 - - L ko:K07498 - ko00000 DDE domain
FMIBIEHO_01430 8.35e-304 - - - G - - - Polysaccharide deacetylase
FMIBIEHO_01431 8.84e-154 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01432 5.57e-288 - - - L - - - MULE transposase domain
FMIBIEHO_01433 1.9e-21 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_01434 5.23e-75 - - - L - - - Helix-turn-helix domain
FMIBIEHO_01435 0.000118 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FMIBIEHO_01436 2.66e-66 - - - S - - - Protein of unknown function (DUF975)
FMIBIEHO_01437 1.71e-122 tnpR1 - - L - - - Resolvase, N terminal domain
FMIBIEHO_01438 3.13e-175 - - - KL - - - HELICc2
FMIBIEHO_01439 1.99e-47 - - - Q - - - ubiE/COQ5 methyltransferase family
FMIBIEHO_01440 2.8e-228 - - - L - - - Transposase and inactivated derivatives, IS30 family
FMIBIEHO_01441 6.26e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
FMIBIEHO_01442 6.48e-215 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
FMIBIEHO_01443 5.5e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
FMIBIEHO_01444 6.86e-256 - - - K - - - Helix-turn-helix XRE-family like proteins
FMIBIEHO_01445 3.02e-61 - - - L - - - MULE transposase domain
FMIBIEHO_01446 2.08e-106 - - - L - - - MULE transposase domain
FMIBIEHO_01447 1.07e-53 - - - L - - - MULE transposase domain
FMIBIEHO_01449 4.52e-126 - - - - - - - -
FMIBIEHO_01450 1.36e-100 - - - F - - - Nucleoside 2-deoxyribosyltransferase
FMIBIEHO_01451 5.46e-233 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
FMIBIEHO_01453 4.22e-21 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
FMIBIEHO_01454 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Aluminium induced protein
FMIBIEHO_01456 3.98e-181 - - - L ko:K07497 - ko00000 Transposase and inactivated derivatives
FMIBIEHO_01457 2.24e-11 - - - S - - - Bacterial transferase hexapeptide (six repeats)
FMIBIEHO_01458 7.95e-153 - - - IQ - - - Enoyl-(Acyl carrier protein) reductase
FMIBIEHO_01459 2.89e-252 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
FMIBIEHO_01460 2.47e-13 - - - K - - - transcriptional
FMIBIEHO_01461 1.56e-67 - - - S - - - Sugar efflux transporter for intercellular exchange
FMIBIEHO_01462 3.03e-74 - - - S - - - Antibiotic biosynthesis monooxygenase
FMIBIEHO_01463 2.05e-59 - - - S - - - Protein conserved in bacteria
FMIBIEHO_01464 1.35e-125 ydeQ - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
FMIBIEHO_01465 3.71e-194 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
FMIBIEHO_01466 1.3e-237 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMIBIEHO_01467 2e-82 - - - S - - - Domain of unknown function (DUF4440)
FMIBIEHO_01468 9.84e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FMIBIEHO_01469 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
FMIBIEHO_01470 1.3e-199 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
FMIBIEHO_01471 8.64e-225 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
FMIBIEHO_01472 6.59e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FMIBIEHO_01473 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
FMIBIEHO_01474 3.97e-174 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_01476 5.48e-70 - - - S - - - mazG nucleotide pyrophosphohydrolase
FMIBIEHO_01477 5.34e-140 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
FMIBIEHO_01478 2.06e-297 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FMIBIEHO_01479 1.15e-299 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
FMIBIEHO_01480 9.97e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FMIBIEHO_01481 1.15e-208 - - - S - - - Tetratricopeptide repeat
FMIBIEHO_01482 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FMIBIEHO_01483 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
FMIBIEHO_01484 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FMIBIEHO_01485 2.9e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
FMIBIEHO_01486 1.63e-236 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
FMIBIEHO_01487 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
FMIBIEHO_01488 8.66e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
FMIBIEHO_01489 4.22e-127 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
FMIBIEHO_01490 1.38e-252 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
FMIBIEHO_01491 1.45e-114 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FMIBIEHO_01492 1.27e-128 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
FMIBIEHO_01493 1.31e-63 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
FMIBIEHO_01494 1.45e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
FMIBIEHO_01495 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
FMIBIEHO_01496 1.96e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
FMIBIEHO_01497 1.55e-65 yktA - - S - - - Belongs to the UPF0223 family
FMIBIEHO_01498 8.59e-133 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
FMIBIEHO_01499 6.12e-98 - - - - - - - -
FMIBIEHO_01500 8.83e-43 ykzG - - S - - - Belongs to the UPF0356 family
FMIBIEHO_01501 1.2e-238 - - - I - - - Diacylglycerol kinase catalytic
FMIBIEHO_01502 2.39e-98 - - - P - - - ArsC family
FMIBIEHO_01503 3.81e-228 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FMIBIEHO_01504 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
FMIBIEHO_01505 9.37e-159 - - - S - - - repeat protein
FMIBIEHO_01506 1.11e-156 pgm6 - - G - - - phosphoglycerate mutase
FMIBIEHO_01507 1.08e-218 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
FMIBIEHO_01508 0.0 - - - S - - - amidohydrolase
FMIBIEHO_01509 1.2e-283 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
FMIBIEHO_01510 7.86e-77 XK27_04120 - - S - - - Putative amino acid metabolism
FMIBIEHO_01511 3.26e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FMIBIEHO_01512 2.68e-08 - - - - - - - -
FMIBIEHO_01513 1.28e-126 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
FMIBIEHO_01514 9.99e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
FMIBIEHO_01515 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FMIBIEHO_01517 6.19e-143 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
FMIBIEHO_01518 1.75e-186 ylmH - - S - - - S4 domain protein
FMIBIEHO_01519 7.27e-56 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
FMIBIEHO_01520 2.49e-100 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
FMIBIEHO_01521 9.01e-294 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FMIBIEHO_01522 1.97e-297 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
FMIBIEHO_01523 5.43e-193 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
FMIBIEHO_01524 2.06e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FMIBIEHO_01525 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FMIBIEHO_01526 4.46e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FMIBIEHO_01527 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
FMIBIEHO_01528 5.28e-31 ftsL - - D - - - Cell division protein FtsL
FMIBIEHO_01529 5.37e-221 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
FMIBIEHO_01530 7.65e-104 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
FMIBIEHO_01531 6.91e-76 - - - - - - - -
FMIBIEHO_01532 4.5e-12 - - - S - - - Protein of unknown function (DUF4044)
FMIBIEHO_01533 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
FMIBIEHO_01534 2.01e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
FMIBIEHO_01535 9.18e-207 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
FMIBIEHO_01536 4.62e-252 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
FMIBIEHO_01537 5.39e-221 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
FMIBIEHO_01538 9.49e-197 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FMIBIEHO_01539 5.24e-159 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
FMIBIEHO_01540 1.03e-147 yjbH - - Q - - - Thioredoxin
FMIBIEHO_01541 2.06e-263 coiA - - S ko:K06198 - ko00000 Competence protein
FMIBIEHO_01542 8.81e-152 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
FMIBIEHO_01543 1.12e-90 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
FMIBIEHO_01564 1.01e-142 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
FMIBIEHO_01565 2.65e-21 - - - S - - - Protein of unknown function (DUF1461)
FMIBIEHO_01566 1.01e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
FMIBIEHO_01567 9.43e-127 yutD - - S - - - Protein of unknown function (DUF1027)
FMIBIEHO_01568 2.73e-147 - - - S - - - Calcineurin-like phosphoesterase
FMIBIEHO_01569 9.57e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FMIBIEHO_01570 9.14e-205 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
FMIBIEHO_01575 8.88e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
FMIBIEHO_01576 2.13e-212 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
FMIBIEHO_01577 1.33e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
FMIBIEHO_01578 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
FMIBIEHO_01579 1.87e-110 - - - M - - - PFAM NLP P60 protein
FMIBIEHO_01580 5.01e-172 yebC - - K - - - Transcriptional regulatory protein
FMIBIEHO_01581 6.95e-182 - - - - - - - -
FMIBIEHO_01582 5.94e-238 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
FMIBIEHO_01583 1.08e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
FMIBIEHO_01584 4.62e-92 - - - - - - - -
FMIBIEHO_01585 5.14e-68 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
FMIBIEHO_01586 4.32e-200 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
FMIBIEHO_01587 1.75e-193 - - - S - - - haloacid dehalogenase-like hydrolase
FMIBIEHO_01588 3.33e-123 - - - S ko:K07095 - ko00000 Phosphoesterase
FMIBIEHO_01589 2.65e-140 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FMIBIEHO_01590 6.11e-188 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
FMIBIEHO_01591 1.75e-123 yslB - - S - - - Protein of unknown function (DUF2507)
FMIBIEHO_01592 7.57e-286 - - - P - - - Chloride transporter, ClC family
FMIBIEHO_01593 1.66e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
FMIBIEHO_01594 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
FMIBIEHO_01595 2.23e-119 cvpA - - S - - - Colicin V production protein
FMIBIEHO_01596 3.2e-211 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FMIBIEHO_01597 3.99e-55 yrzB - - S - - - Belongs to the UPF0473 family
FMIBIEHO_01598 4.97e-97 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FMIBIEHO_01599 1.06e-57 yrzL - - S - - - Belongs to the UPF0297 family
FMIBIEHO_01600 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FMIBIEHO_01601 1.7e-300 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
FMIBIEHO_01602 2.8e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
FMIBIEHO_01603 1.11e-68 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
FMIBIEHO_01604 8.89e-226 - 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 queuine tRNA-ribosyltransferase activity
FMIBIEHO_01605 3.61e-243 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
FMIBIEHO_01606 5.09e-135 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
FMIBIEHO_01607 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FMIBIEHO_01608 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FMIBIEHO_01609 2.27e-305 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
FMIBIEHO_01610 1.36e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FMIBIEHO_01611 1.97e-294 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
FMIBIEHO_01612 1.79e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FMIBIEHO_01613 1.64e-151 - - - S - - - Helix-turn-helix domain
FMIBIEHO_01614 0.0 ymfH - - S - - - Peptidase M16
FMIBIEHO_01615 6.37e-296 ymfF - - S - - - Peptidase M16 inactive domain protein
FMIBIEHO_01616 3.88e-204 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
FMIBIEHO_01617 4.86e-149 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_01618 3.81e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
FMIBIEHO_01619 9.04e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
FMIBIEHO_01620 1.37e-187 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
FMIBIEHO_01621 1.34e-232 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
FMIBIEHO_01622 5.3e-150 radC - - L ko:K03630 - ko00000 DNA repair protein
FMIBIEHO_01623 0.0 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
FMIBIEHO_01624 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
FMIBIEHO_01625 3.11e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FMIBIEHO_01629 7.62e-51 - - - S - - - zinc-ribbon domain
FMIBIEHO_01630 1.61e-52 - - - - - - - -
FMIBIEHO_01631 5.07e-43 - - - M - - - LysM domain
FMIBIEHO_01632 3.17e-260 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
FMIBIEHO_01633 3.95e-278 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
FMIBIEHO_01634 2.03e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FMIBIEHO_01635 5.83e-273 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
FMIBIEHO_01636 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
FMIBIEHO_01637 5.1e-140 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FMIBIEHO_01638 7.29e-20 - - - L - - - Replication protein
FMIBIEHO_01639 5.35e-68 - - - M - - - lysozyme activity
FMIBIEHO_01640 8.21e-26 - - - M - - - lysozyme activity
FMIBIEHO_01644 4.04e-63 - - - S - - - peptidoglycan catabolic process
FMIBIEHO_01645 7.31e-21 - - - LM - - - gp58-like protein
FMIBIEHO_01646 1.51e-55 - - - S - - - peptidoglycan catabolic process
FMIBIEHO_01647 3.36e-289 - - - L - - - MULE transposase domain
FMIBIEHO_01650 5.13e-250 - - - S - - - peptidoglycan catabolic process
FMIBIEHO_01651 1.42e-50 - - - S - - - Pfam:Phage_TAC_12
FMIBIEHO_01652 2.79e-108 - - - S - - - Phage major tail protein 2
FMIBIEHO_01653 3.23e-57 - - - - - - - -
FMIBIEHO_01654 1.07e-60 - - - S - - - Phage gp6-like head-tail connector protein
FMIBIEHO_01655 2.9e-33 - - - S - - - exonuclease activity
FMIBIEHO_01656 1.07e-60 - - - S - - - Phage gp6-like head-tail connector protein
FMIBIEHO_01657 5.22e-152 - - - - - - - -
FMIBIEHO_01658 3.46e-87 - - - S - - - aminoacyl-tRNA ligase activity
FMIBIEHO_01660 2.29e-177 - - - S - - - Phage Mu protein F like protein
FMIBIEHO_01661 4.01e-262 - - - S - - - Phage portal protein, SPP1 Gp6-like
FMIBIEHO_01662 2.64e-201 yqaT - - S ko:K06909 - ko00000 Phage terminase, large subunit
FMIBIEHO_01664 2.6e-55 - - - L ko:K07474 - ko00000 Terminase small subunit
FMIBIEHO_01665 6.64e-44 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
FMIBIEHO_01666 8.51e-67 - - - K - - - Protein of unknown function (DUF4065)
FMIBIEHO_01670 1.03e-33 - - - S - - - Protein of unknown function (DUF1064)
FMIBIEHO_01671 3.37e-14 - - - K - - - Cro/C1-type HTH DNA-binding domain
FMIBIEHO_01673 3.21e-50 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
FMIBIEHO_01674 5.53e-59 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
FMIBIEHO_01675 3.42e-15 - - - L - - - DnaD domain protein
FMIBIEHO_01676 4.56e-73 - - - S - - - Single-strand binding protein family
FMIBIEHO_01677 3.54e-62 - - - S - - - PDDEXK-like domain of unknown function (DUF3799)
FMIBIEHO_01678 3.51e-94 - - - S - - - PDDEXK-like domain of unknown function (DUF3799)
FMIBIEHO_01679 4.03e-193 - - - S - - - DNA metabolic process
FMIBIEHO_01683 1.67e-30 - - - - - - - -
FMIBIEHO_01688 2.16e-151 - - - S - - - DNA binding
FMIBIEHO_01692 2.12e-23 - - - K - - - Helix-turn-helix
FMIBIEHO_01694 3.64e-58 - - - NU - - - Domain of unknown function (DUF5067)
FMIBIEHO_01695 1.27e-18 yrvD - - S - - - Pfam:DUF1049
FMIBIEHO_01698 1.87e-269 int3 - - L - - - Belongs to the 'phage' integrase family
FMIBIEHO_01700 1.25e-15 - - - S - - - YjcQ protein
FMIBIEHO_01701 1.67e-187 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
FMIBIEHO_01702 2.3e-173 - - - S - - - Membrane
FMIBIEHO_01703 1.52e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
FMIBIEHO_01704 8.04e-111 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
FMIBIEHO_01705 1.3e-300 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
FMIBIEHO_01707 6.08e-107 uspA - - T - - - universal stress protein
FMIBIEHO_01708 1.7e-195 - - - K - - - Helix-turn-helix XRE-family like proteins
FMIBIEHO_01709 1.94e-139 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01710 1.99e-127 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01711 2.38e-274 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
FMIBIEHO_01712 9.42e-232 - - - S - - - Protein of unknown function (DUF2785)
FMIBIEHO_01714 5.09e-283 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
FMIBIEHO_01715 7.67e-43 - - - S - - - Protein of unknown function (DUF2969)
FMIBIEHO_01716 9.42e-234 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
FMIBIEHO_01717 4.64e-276 - - - M - - - EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
FMIBIEHO_01718 8.07e-40 - - - S - - - Protein of unknown function (DUF1146)
FMIBIEHO_01719 1.19e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
FMIBIEHO_01720 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FMIBIEHO_01721 1.78e-213 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FMIBIEHO_01722 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FMIBIEHO_01723 3.51e-119 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FMIBIEHO_01724 5.83e-82 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FMIBIEHO_01725 2.13e-27 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FMIBIEHO_01726 5.66e-168 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
FMIBIEHO_01727 1.1e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
FMIBIEHO_01728 2.24e-164 yibF - - S - - - overlaps another CDS with the same product name
FMIBIEHO_01729 2e-252 yibE - - S - - - overlaps another CDS with the same product name
FMIBIEHO_01730 3.86e-149 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FMIBIEHO_01731 2.12e-292 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FMIBIEHO_01732 8.28e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
FMIBIEHO_01733 9.13e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
FMIBIEHO_01734 5.36e-208 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FMIBIEHO_01735 1.78e-139 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
FMIBIEHO_01736 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
FMIBIEHO_01737 7.49e-181 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
FMIBIEHO_01738 2.31e-63 - - - - - - - -
FMIBIEHO_01739 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FMIBIEHO_01740 2.65e-245 ampC - - V - - - Beta-lactamase
FMIBIEHO_01741 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
FMIBIEHO_01742 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_01743 2.07e-102 - - - K - - - Winged helix-turn-helix DNA-binding
FMIBIEHO_01744 3.24e-10 - - - - - - - -
FMIBIEHO_01746 2.67e-75 - - - - - - - -
FMIBIEHO_01748 6.37e-169 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
FMIBIEHO_01749 5.46e-186 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FMIBIEHO_01750 9.18e-206 yvgN - - S - - - Aldo keto reductase
FMIBIEHO_01751 1.49e-157 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
FMIBIEHO_01752 5e-111 - - - K - - - GNAT family
FMIBIEHO_01754 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
FMIBIEHO_01755 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
FMIBIEHO_01756 1.88e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
FMIBIEHO_01757 4.93e-212 - - - L - - - PFAM Integrase catalytic region
FMIBIEHO_01758 3.8e-31 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
FMIBIEHO_01759 1.44e-195 - - - U ko:K05340 - ko00000,ko02000 sugar transport
FMIBIEHO_01760 0.0 yclK - - T - - - Histidine kinase
FMIBIEHO_01761 1.39e-170 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
FMIBIEHO_01763 1.04e-75 manO - - S - - - Domain of unknown function (DUF956)
FMIBIEHO_01764 1.37e-219 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
FMIBIEHO_01765 2.38e-164 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
FMIBIEHO_01766 1.05e-229 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
FMIBIEHO_01767 1.5e-231 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
FMIBIEHO_01768 2.52e-116 - - - K - - - Domain of unknown function (DUF1836)
FMIBIEHO_01769 3.14e-191 yitS - - S - - - EDD domain protein, DegV family
FMIBIEHO_01770 2.71e-164 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
FMIBIEHO_01771 3.48e-215 - - - K - - - LysR substrate binding domain
FMIBIEHO_01772 1.64e-220 - - - S - - - Conserved hypothetical protein 698
FMIBIEHO_01773 7.87e-112 lytE - - M - - - Lysin motif
FMIBIEHO_01774 2.13e-193 XK27_02985 - - S - - - Sucrose-6F-phosphate phosphohydrolase
FMIBIEHO_01775 5.83e-263 oatA - - I - - - Acyltransferase
FMIBIEHO_01776 2.55e-68 - - - - - - - -
FMIBIEHO_01777 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
FMIBIEHO_01778 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FMIBIEHO_01779 1.69e-151 ybbR - - S - - - YbbR-like protein
FMIBIEHO_01780 1.61e-192 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
FMIBIEHO_01781 2.34e-212 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
FMIBIEHO_01782 4e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
FMIBIEHO_01783 5.51e-118 - - - K - - - Acetyltransferase (GNAT) domain
FMIBIEHO_01784 6.98e-104 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
FMIBIEHO_01785 9.74e-229 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
FMIBIEHO_01786 5.28e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FMIBIEHO_01787 1.94e-138 - - - - - - - -
FMIBIEHO_01788 4.66e-110 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
FMIBIEHO_01789 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
FMIBIEHO_01790 6.82e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
FMIBIEHO_01791 0.0 eriC - - P ko:K03281 - ko00000 chloride
FMIBIEHO_01792 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
FMIBIEHO_01793 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
FMIBIEHO_01794 2.92e-184 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
FMIBIEHO_01795 4.22e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
FMIBIEHO_01796 2.17e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
FMIBIEHO_01797 3.82e-23 - - - - - - - -
FMIBIEHO_01798 7.41e-313 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_01802 2.96e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
FMIBIEHO_01803 1.77e-156 - 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FMIBIEHO_01804 2.34e-214 whiA - - K ko:K09762 - ko00000 May be required for sporulation
FMIBIEHO_01805 2e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
FMIBIEHO_01806 3.72e-204 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
FMIBIEHO_01807 2.51e-261 - - - - - - - -
FMIBIEHO_01808 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
FMIBIEHO_01809 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
FMIBIEHO_01811 7.18e-145 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
FMIBIEHO_01812 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
FMIBIEHO_01813 1.7e-175 - - - S - - - haloacid dehalogenase-like hydrolase
FMIBIEHO_01814 1.59e-217 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
FMIBIEHO_01815 2.39e-254 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
FMIBIEHO_01816 7.3e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
FMIBIEHO_01817 2.83e-199 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
FMIBIEHO_01818 4.74e-166 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
FMIBIEHO_01819 2.85e-211 - - - L - - - PFAM Integrase catalytic region
FMIBIEHO_01820 1.9e-109 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
FMIBIEHO_01821 1.84e-100 yphH - - S - - - Cupin domain
FMIBIEHO_01822 8.07e-161 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01823 5.92e-104 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01824 6.82e-73 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_01825 1.25e-240 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FMIBIEHO_01826 2.97e-287 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
FMIBIEHO_01827 2.92e-186 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
FMIBIEHO_01828 7.64e-220 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
FMIBIEHO_01829 9.09e-236 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
FMIBIEHO_01830 3.09e-208 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FMIBIEHO_01831 1.68e-227 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FMIBIEHO_01832 4.15e-69 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
FMIBIEHO_01833 1.12e-21 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
FMIBIEHO_01834 1.45e-257 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FMIBIEHO_01835 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
FMIBIEHO_01836 4.64e-124 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FMIBIEHO_01837 4.34e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
FMIBIEHO_01838 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
FMIBIEHO_01839 1.7e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
FMIBIEHO_01840 4.12e-50 - - - - - - - -
FMIBIEHO_01841 0.0 ydaO - - E - - - amino acid
FMIBIEHO_01842 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
FMIBIEHO_01843 5.71e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FMIBIEHO_01844 8.05e-149 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
FMIBIEHO_01845 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
FMIBIEHO_01846 1.04e-224 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
FMIBIEHO_01847 9.66e-117 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
FMIBIEHO_01848 1.55e-174 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
FMIBIEHO_01849 2.69e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
FMIBIEHO_01850 2.25e-206 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FMIBIEHO_01851 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
FMIBIEHO_01852 1.13e-97 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FMIBIEHO_01853 3.46e-94 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
FMIBIEHO_01854 1.32e-291 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
FMIBIEHO_01855 2.67e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
FMIBIEHO_01856 2.76e-219 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
FMIBIEHO_01857 4.18e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
FMIBIEHO_01858 2.27e-220 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FMIBIEHO_01859 2.27e-98 - - - K - - - Transcriptional regulator, MarR family
FMIBIEHO_01860 3.83e-100 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
FMIBIEHO_01862 3.65e-250 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FMIBIEHO_01863 1.93e-143 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
FMIBIEHO_01864 2.78e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
FMIBIEHO_01865 1.61e-274 arcT - - E - - - Aminotransferase
FMIBIEHO_01866 8.37e-282 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
FMIBIEHO_01867 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
FMIBIEHO_01868 3.45e-305 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
FMIBIEHO_01869 4.08e-218 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
FMIBIEHO_01870 2.08e-239 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FMIBIEHO_01871 7.82e-203 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
FMIBIEHO_01872 8.55e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
FMIBIEHO_01873 6.78e-221 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
FMIBIEHO_01874 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FMIBIEHO_01875 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
FMIBIEHO_01876 4.02e-189 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
FMIBIEHO_01877 2.83e-202 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FMIBIEHO_01878 2.47e-74 yabA - - L - - - Involved in initiation control of chromosome replication
FMIBIEHO_01879 2.36e-247 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
FMIBIEHO_01880 7.84e-71 yaaQ - - S - - - Cyclic-di-AMP receptor
FMIBIEHO_01881 2.41e-149 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FMIBIEHO_01882 2.06e-28 - - - S - - - Protein of unknown function (DUF2508)
FMIBIEHO_01883 6.48e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FMIBIEHO_01884 3.97e-60 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FMIBIEHO_01885 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FMIBIEHO_01887 3.69e-113 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
FMIBIEHO_01888 6.56e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
FMIBIEHO_01889 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMIBIEHO_01890 8.93e-250 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMIBIEHO_01891 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
FMIBIEHO_01893 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
FMIBIEHO_01894 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FMIBIEHO_01895 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
FMIBIEHO_01896 4.34e-235 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
FMIBIEHO_01897 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
FMIBIEHO_01898 8.24e-71 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
FMIBIEHO_01899 3.88e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FMIBIEHO_01900 2.22e-312 steT - - E ko:K03294 - ko00000 amino acid
FMIBIEHO_01901 1.96e-156 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
FMIBIEHO_01902 3.34e-68 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FMIBIEHO_01903 8.34e-127 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
FMIBIEHO_01904 2.04e-31 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
FMIBIEHO_01905 7.09e-30 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
FMIBIEHO_01906 5.57e-135 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
FMIBIEHO_01907 3.52e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FMIBIEHO_01908 1.25e-93 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
FMIBIEHO_01909 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
FMIBIEHO_01910 9.63e-130 ywlG - - S - - - Belongs to the UPF0340 family
FMIBIEHO_01911 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FMIBIEHO_01912 1.93e-264 yacL - - S - - - domain protein
FMIBIEHO_01913 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FMIBIEHO_01914 3.55e-127 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
FMIBIEHO_01915 6.52e-73 HA62_12640 - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
FMIBIEHO_01916 5.86e-157 - 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FMIBIEHO_01917 3.45e-144 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
FMIBIEHO_01918 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
FMIBIEHO_01919 3.02e-61 - - - L - - - MULE transposase domain
FMIBIEHO_01920 5.5e-150 - - - L - - - MULE transposase domain
FMIBIEHO_01921 3.77e-214 - - - I - - - alpha/beta hydrolase fold
FMIBIEHO_01922 7.78e-165 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FMIBIEHO_01923 1.25e-212 - - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
FMIBIEHO_01924 5.3e-240 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
FMIBIEHO_01925 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
FMIBIEHO_01927 6.97e-109 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
FMIBIEHO_01928 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
FMIBIEHO_01929 2.23e-194 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
FMIBIEHO_01930 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FMIBIEHO_01931 8.7e-166 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
FMIBIEHO_01932 1.56e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
FMIBIEHO_01933 4.67e-149 - - - - - - - -
FMIBIEHO_01936 5.56e-211 - - - S - - - Calcineurin-like phosphoesterase
FMIBIEHO_01937 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
FMIBIEHO_01938 3.91e-258 - - - D - - - nuclear chromosome segregation
FMIBIEHO_01939 2.89e-186 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01940 1.71e-95 - - - L - - - PFAM transposase, IS4 family protein
FMIBIEHO_01942 3.65e-61 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01943 2.87e-306 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
FMIBIEHO_01944 9.89e-199 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
FMIBIEHO_01945 6.89e-162 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
FMIBIEHO_01946 1.95e-290 - - - L - - - MULE transposase domain
FMIBIEHO_01947 1.19e-146 - - - O - - - Bacterial dnaA protein
FMIBIEHO_01948 3.08e-173 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01949 6.29e-217 yeeC - - P - - - T5orf172
FMIBIEHO_01950 0.0 - - - L - - - DEAD-like helicases superfamily
FMIBIEHO_01951 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
FMIBIEHO_01953 1.46e-25 B4168_4126 - - L ko:K07493 - ko00000 Transposase
FMIBIEHO_01954 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_01956 4.43e-16 - - - L ko:K07483 - ko00000 Helix-turn-helix domain
FMIBIEHO_01957 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
FMIBIEHO_01958 9.94e-148 - - - T - - - Region found in RelA / SpoT proteins
FMIBIEHO_01959 1.65e-101 dltr - - K - - - response regulator
FMIBIEHO_01960 5.13e-165 sptS - - T - - - Histidine kinase
FMIBIEHO_01961 2.29e-223 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
FMIBIEHO_01962 3.98e-135 - - - K - - - acetyltransferase
FMIBIEHO_01963 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FMIBIEHO_01964 2.62e-202 - - - EG - - - EamA-like transporter family
FMIBIEHO_01965 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
FMIBIEHO_01966 2.5e-153 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
FMIBIEHO_01967 5.5e-155 pgm3 - - G - - - phosphoglycerate mutase
FMIBIEHO_01968 2.06e-297 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FMIBIEHO_01969 3.6e-265 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
FMIBIEHO_01970 3.55e-173 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
FMIBIEHO_01971 0.0 - - - E - - - amino acid
FMIBIEHO_01972 4.58e-114 - - - K - - - FR47-like protein
FMIBIEHO_01973 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_01974 2.16e-58 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01975 1.05e-111 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_01976 9.65e-81 - - - L - - - An automated process has identified a potential problem with this gene model
FMIBIEHO_01977 2.43e-312 yhgE - - V ko:K01421 - ko00000 domain protein
FMIBIEHO_01978 4.23e-122 - - - K - - - Transcriptional regulator (TetR family)
FMIBIEHO_01979 2.38e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
FMIBIEHO_01980 6.75e-215 - - - - - - - -
FMIBIEHO_01981 4.69e-10 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
FMIBIEHO_01982 7.28e-110 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
FMIBIEHO_01983 9.61e-137 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
FMIBIEHO_01984 8.97e-95 - - - F - - - Nudix hydrolase
FMIBIEHO_01985 2.32e-260 yhdG - - E ko:K03294 - ko00000 Amino Acid
FMIBIEHO_01986 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
FMIBIEHO_01987 2.73e-227 - 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
FMIBIEHO_01988 2.41e-148 - - - S - - - HAD hydrolase, family IA, variant
FMIBIEHO_01989 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
FMIBIEHO_01990 8.41e-235 - 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
FMIBIEHO_01991 2.27e-218 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleotide reductase, small chain
FMIBIEHO_01992 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FMIBIEHO_01993 1.64e-108 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
FMIBIEHO_01994 8.3e-141 yciB - - M - - - ErfK YbiS YcfS YnhG
FMIBIEHO_01996 1.99e-263 yngD - - S ko:K07097 - ko00000 DHHA1 domain
FMIBIEHO_01997 0.0 - - - S - - - ABC transporter, ATP-binding protein
FMIBIEHO_01998 5.66e-231 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
FMIBIEHO_01999 3.76e-193 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
FMIBIEHO_02000 3.24e-171 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_02002 2.17e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
FMIBIEHO_02003 1.29e-298 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
FMIBIEHO_02004 7.93e-217 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
FMIBIEHO_02005 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
FMIBIEHO_02006 4.17e-236 fruR3 - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
FMIBIEHO_02007 9.89e-207 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
FMIBIEHO_02008 1.72e-213 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FMIBIEHO_02009 3.45e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
FMIBIEHO_02010 5.82e-182 yceF - - P ko:K05794 - ko00000 membrane
FMIBIEHO_02011 1.12e-212 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
FMIBIEHO_02012 3.77e-217 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
FMIBIEHO_02013 2.15e-299 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
FMIBIEHO_02014 5.62e-192 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
FMIBIEHO_02015 3.31e-162 pgm3 - - G - - - phosphoglycerate mutase family
FMIBIEHO_02016 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
FMIBIEHO_02017 1.3e-110 - - - - - - - -
FMIBIEHO_02018 7.69e-142 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
FMIBIEHO_02019 8.02e-130 dpsB - - P - - - Belongs to the Dps family
FMIBIEHO_02020 6.69e-47 copZ - - P - - - Heavy-metal-associated domain
FMIBIEHO_02021 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
FMIBIEHO_02022 1.51e-235 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
FMIBIEHO_02023 3.41e-231 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
FMIBIEHO_02024 1.17e-130 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
FMIBIEHO_02025 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_02026 1.44e-147 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
FMIBIEHO_02027 8.87e-23 - - - - - - - -
FMIBIEHO_02028 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
FMIBIEHO_02029 7.9e-246 lplL 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Bacterial lipoate protein ligase C-terminus
FMIBIEHO_02030 1.1e-94 - - - O - - - OsmC-like protein
FMIBIEHO_02031 5.3e-240 ybcH - - D ko:K06889 - ko00000 Alpha beta
FMIBIEHO_02032 2.22e-98 - - - K - - - Transcriptional regulator
FMIBIEHO_02033 1.92e-203 - - - - - - - -
FMIBIEHO_02034 1.25e-09 - - - - - - - -
FMIBIEHO_02035 6.25e-78 - - - - - - - -
FMIBIEHO_02036 2.16e-98 uspA3 - - T - - - universal stress protein
FMIBIEHO_02038 3.45e-175 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
FMIBIEHO_02039 2.72e-314 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
FMIBIEHO_02040 0.0 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FMIBIEHO_02041 9.75e-175 tal 2.2.1.2 - H ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase/Fructose-6-phosphate aldolase
FMIBIEHO_02042 5.46e-161 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FMIBIEHO_02043 4.21e-156 tkt 2.2.1.1 - H ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FMIBIEHO_02044 3.68e-75 - - - L - - - Helix-turn-helix domain
FMIBIEHO_02045 1.13e-189 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_02046 4.33e-236 hoxN - - U ko:K07241 - ko00000,ko02000 High-affinity nickel-transport protein
FMIBIEHO_02047 1.14e-191 larE - - S ko:K06864 - ko00000 NAD synthase
FMIBIEHO_02048 1.33e-166 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
FMIBIEHO_02049 1.3e-301 larC 4.99.1.12 - S ko:K09121 - ko00000,ko01000 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
FMIBIEHO_02050 2.36e-168 larB - - S ko:K06898 - ko00000 AIR carboxylase
FMIBIEHO_02051 1.24e-305 larA 5.1.2.1 - S ko:K22373 ko00620,map00620 ko00000,ko00001,ko01000 Domain of unknown function (DUF2088)
FMIBIEHO_02052 1.24e-160 rcfB - - K - - - Crp-like helix-turn-helix domain
FMIBIEHO_02053 5.53e-183 - - - L - - - Transposase and inactivated derivatives, IS30 family
FMIBIEHO_02054 1.36e-315 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_02055 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FMIBIEHO_02056 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
FMIBIEHO_02057 8.61e-89 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
FMIBIEHO_02058 1.52e-211 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FMIBIEHO_02059 2.02e-218 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
FMIBIEHO_02060 2.05e-147 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FMIBIEHO_02061 2.89e-253 - - - S - - - Domain of unknown function (DUF4432)
FMIBIEHO_02062 2.57e-224 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FMIBIEHO_02063 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
FMIBIEHO_02064 5.29e-238 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
FMIBIEHO_02065 0.0 potE - - E - - - Amino Acid
FMIBIEHO_02067 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
FMIBIEHO_02068 7.18e-190 - - - S - - - haloacid dehalogenase-like hydrolase
FMIBIEHO_02069 3.81e-169 gntR - - K - - - UbiC transcription regulator-associated domain protein
FMIBIEHO_02070 4.23e-115 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FMIBIEHO_02071 3.11e-166 - - - - - - - -
FMIBIEHO_02072 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
FMIBIEHO_02073 6.18e-198 - - - G - - - Xylose isomerase domain protein TIM barrel
FMIBIEHO_02075 4.18e-113 - - - K - - - Domain of unknown function (DUF1836)
FMIBIEHO_02076 2.79e-115 - - - GM - - - epimerase
FMIBIEHO_02077 0.0 yhdP - - S - - - Transporter associated domain
FMIBIEHO_02078 3.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
FMIBIEHO_02079 8.99e-99 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
FMIBIEHO_02080 1.26e-266 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
FMIBIEHO_02081 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FMIBIEHO_02082 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FMIBIEHO_02083 2.13e-106 usp5 - - T - - - universal stress protein
FMIBIEHO_02084 1.52e-103 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
FMIBIEHO_02085 2.69e-180 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
FMIBIEHO_02086 1.68e-229 - - - K ko:K02525 - ko00000,ko03000 helix_turn _helix lactose operon repressor
FMIBIEHO_02087 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
FMIBIEHO_02088 1.29e-298 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
FMIBIEHO_02089 6.15e-161 - - - S - - - Membrane
FMIBIEHO_02090 3.15e-38 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_02091 2.61e-187 - - - L - - - 4.5 Transposon and IS
FMIBIEHO_02092 0.0 dld 1.1.5.12 - C ko:K03777 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 D-lactate dehydrogenase, membrane binding
FMIBIEHO_02093 1.37e-288 - - - L - - - MULE transposase domain
FMIBIEHO_02094 3.46e-225 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
FMIBIEHO_02095 4.11e-150 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_02096 8.85e-133 pinR1 - - L - - - Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
FMIBIEHO_02097 7.38e-60 - - - S - - - FRG
FMIBIEHO_02098 3.57e-47 - - - L - - - PFAM transposase, IS4 family protein
FMIBIEHO_02099 1.3e-106 - - - L - - - PFAM transposase, IS4 family protein
FMIBIEHO_02100 5.63e-146 - - - L - - - PFAM UvrD REP helicase
FMIBIEHO_02101 1.2e-181 - - - L ko:K07459 - ko00000 AAA ATPase domain
FMIBIEHO_02102 3.05e-20 - - - L - - - MULE transposase domain
FMIBIEHO_02103 1.72e-08 - - - - - - - -
FMIBIEHO_02104 3.2e-306 yeeA - - V - - - Type II restriction enzyme, methylase subunits
FMIBIEHO_02106 6.37e-93 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FMIBIEHO_02107 1.19e-50 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
FMIBIEHO_02108 1.2e-200 is18 - - L - - - Integrase core domain
FMIBIEHO_02109 2.39e-61 - - - S - - - VIT family
FMIBIEHO_02110 9.3e-180 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
FMIBIEHO_02111 9.13e-27 yycN - - K - - - Acetyltransferase (GNAT) domain
FMIBIEHO_02112 3.07e-110 - - - P - - - Cation efflux family
FMIBIEHO_02113 1.89e-65 tnpR1 - - L - - - Resolvase, N terminal domain
FMIBIEHO_02115 2.48e-62 - - - L ko:K07483 - ko00000 Transposase
FMIBIEHO_02116 1.8e-217 - - - L ko:K07497 - ko00000 Integrase core domain
FMIBIEHO_02117 8.99e-82 - - - S - - - Initiator Replication protein
FMIBIEHO_02118 7.52e-221 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
FMIBIEHO_02120 1.56e-275 - - - M - - - Glycosyl transferase family group 2
FMIBIEHO_02122 2e-81 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_02123 1.97e-185 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_02125 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
FMIBIEHO_02126 7.39e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
FMIBIEHO_02127 5.32e-74 - - - L - - - Putative transposase of IS4/5 family (DUF4096)
FMIBIEHO_02128 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
FMIBIEHO_02129 7.14e-18 - - - L - - - Helix-turn-helix domain
FMIBIEHO_02131 1.71e-95 - - - L - - - PFAM transposase, IS4 family protein
FMIBIEHO_02132 2.14e-72 - - - L - - - Helix-turn-helix domain
FMIBIEHO_02133 2.71e-198 - - - L ko:K07497 - ko00000 hmm pf00665
FMIBIEHO_02134 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
FMIBIEHO_02135 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
FMIBIEHO_02136 8.69e-232 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
FMIBIEHO_02137 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
FMIBIEHO_02138 4.19e-285 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FMIBIEHO_02139 1.63e-232 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
FMIBIEHO_02140 3.95e-184 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
FMIBIEHO_02141 2.44e-125 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
FMIBIEHO_02142 1.21e-48 - - - - - - - -
FMIBIEHO_02143 2.05e-174 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_02144 3.51e-154 - - - U ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
FMIBIEHO_02145 1.09e-180 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
FMIBIEHO_02146 9.08e-71 - - - - - - - -
FMIBIEHO_02147 4.23e-217 - 1.1.1.399, 1.1.1.95 - CH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FMIBIEHO_02148 2.57e-104 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
FMIBIEHO_02149 8.79e-188 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
FMIBIEHO_02150 4.05e-119 ymdB - - S - - - Macro domain protein
FMIBIEHO_02151 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
FMIBIEHO_02152 3e-291 pbuG - - S ko:K06901 - ko00000,ko02000 permease
FMIBIEHO_02153 8.5e-61 - - - - - - - -
FMIBIEHO_02154 1.03e-241 - - - S - - - Putative metallopeptidase domain
FMIBIEHO_02155 2.43e-264 - - - S - - - associated with various cellular activities
FMIBIEHO_02156 2e-150 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
FMIBIEHO_02157 1.42e-85 yeaO - - S - - - Protein of unknown function, DUF488
FMIBIEHO_02159 9.44e-161 yrkL - - S - - - Flavodoxin-like fold
FMIBIEHO_02160 8.76e-73 - - - - - - - -
FMIBIEHO_02161 3.04e-140 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
FMIBIEHO_02162 6.55e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FMIBIEHO_02163 2.79e-137 - - - - - - - -
FMIBIEHO_02164 1.11e-35 - - - - - - - -
FMIBIEHO_02165 1.42e-216 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
FMIBIEHO_02166 7.65e-314 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
FMIBIEHO_02167 3.55e-61 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
FMIBIEHO_02168 7.5e-100 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
FMIBIEHO_02169 2.9e-158 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
FMIBIEHO_02170 3.32e-208 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
FMIBIEHO_02171 3.89e-139 - - - K - - - Bacterial regulatory proteins, tetR family
FMIBIEHO_02172 5.52e-241 - - - E - - - Zinc-binding dehydrogenase
FMIBIEHO_02173 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
FMIBIEHO_02174 3.46e-68 - - - - - - - -
FMIBIEHO_02175 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FMIBIEHO_02176 3.36e-110 - - - L - - - nuclease
FMIBIEHO_02177 1.2e-206 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
FMIBIEHO_02178 5.74e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_02179 2.78e-72 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_02180 9.71e-317 tnpA1 - - L - - - PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
FMIBIEHO_02181 1.16e-146 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
FMIBIEHO_02182 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FMIBIEHO_02183 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FMIBIEHO_02184 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
FMIBIEHO_02185 4.35e-284 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
FMIBIEHO_02186 2.07e-75 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
FMIBIEHO_02187 1.03e-105 - - - L ko:K07491 - ko00000 Transposase IS200 like
FMIBIEHO_02188 2.44e-305 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
FMIBIEHO_02189 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
FMIBIEHO_02190 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FMIBIEHO_02191 1.83e-198 jag - - S ko:K06346 - ko00000 R3H domain protein
FMIBIEHO_02192 4.99e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FMIBIEHO_02193 2.64e-75 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
FMIBIEHO_02194 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)