ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
LGCOMDED_00001 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
LGCOMDED_00002 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
LGCOMDED_00003 1.17e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LGCOMDED_00004 7.4e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGCOMDED_00005 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
LGCOMDED_00006 2.72e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LGCOMDED_00007 2.24e-141 - - - - - - - -
LGCOMDED_00008 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGCOMDED_00009 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGCOMDED_00010 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LGCOMDED_00011 1.2e-30 ymzA - - - - - - -
LGCOMDED_00012 1.63e-31 - - - - - - - -
LGCOMDED_00013 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LGCOMDED_00014 9.69e-224 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGCOMDED_00015 5.41e-76 ymaF - - S - - - YmaF family
LGCOMDED_00017 1.21e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LGCOMDED_00018 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
LGCOMDED_00019 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
LGCOMDED_00020 3.96e-163 ymaC - - S - - - Replication protein
LGCOMDED_00022 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
LGCOMDED_00023 1.88e-207 - - - S - - - Metallo-beta-lactamase superfamily
LGCOMDED_00024 8.03e-81 ymzB - - - - - - -
LGCOMDED_00025 4.14e-134 pksA - - K - - - Transcriptional regulator
LGCOMDED_00026 5.38e-125 ymcC - - S - - - Membrane
LGCOMDED_00027 6.4e-90 - - - S - - - Regulatory protein YrvL
LGCOMDED_00028 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGCOMDED_00029 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGCOMDED_00030 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
LGCOMDED_00031 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
LGCOMDED_00032 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGCOMDED_00033 5.89e-278 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LGCOMDED_00034 3.38e-252 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LGCOMDED_00035 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
LGCOMDED_00036 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
LGCOMDED_00037 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
LGCOMDED_00038 2.82e-280 pbpX - - V - - - Beta-lactamase
LGCOMDED_00039 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGCOMDED_00040 3.56e-298 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
LGCOMDED_00041 3.34e-132 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGCOMDED_00042 2.29e-172 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
LGCOMDED_00043 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
LGCOMDED_00044 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
LGCOMDED_00045 4.27e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LGCOMDED_00046 2.37e-309 ymfH - - S - - - zinc protease
LGCOMDED_00047 3.17e-297 albE - - S - - - Peptidase M16
LGCOMDED_00048 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_00049 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_00050 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LGCOMDED_00051 4.94e-44 - - - S - - - YlzJ-like protein
LGCOMDED_00052 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
LGCOMDED_00053 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGCOMDED_00054 1.57e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGCOMDED_00055 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LGCOMDED_00056 1.66e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGCOMDED_00057 4.73e-140 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LGCOMDED_00058 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
LGCOMDED_00059 1.53e-56 ymxH - - S - - - YlmC YmxH family
LGCOMDED_00060 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
LGCOMDED_00061 6.89e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
LGCOMDED_00062 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LGCOMDED_00063 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LGCOMDED_00064 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
LGCOMDED_00065 4.96e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LGCOMDED_00066 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGCOMDED_00067 1.58e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
LGCOMDED_00068 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LGCOMDED_00069 6.16e-63 ylxQ - - J - - - ribosomal protein
LGCOMDED_00070 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
LGCOMDED_00071 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
LGCOMDED_00072 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
LGCOMDED_00073 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LGCOMDED_00074 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LGCOMDED_00075 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
LGCOMDED_00076 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LGCOMDED_00077 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
LGCOMDED_00078 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LGCOMDED_00079 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LGCOMDED_00080 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
LGCOMDED_00081 1.39e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGCOMDED_00082 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
LGCOMDED_00083 6.62e-99 ylxL - - - - - - -
LGCOMDED_00084 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_00085 1.36e-111 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LGCOMDED_00086 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LGCOMDED_00087 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
LGCOMDED_00088 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
LGCOMDED_00089 2.58e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LGCOMDED_00090 1.49e-198 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
LGCOMDED_00091 1.62e-255 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
LGCOMDED_00092 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGCOMDED_00093 2.74e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGCOMDED_00094 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
LGCOMDED_00095 1.06e-49 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
LGCOMDED_00096 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
LGCOMDED_00097 5.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
LGCOMDED_00098 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
LGCOMDED_00099 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGCOMDED_00100 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LGCOMDED_00101 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
LGCOMDED_00102 2.1e-177 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
LGCOMDED_00103 3.28e-95 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
LGCOMDED_00104 2.21e-312 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
LGCOMDED_00105 2.93e-83 ylxF - - S - - - MgtE intracellular N domain
LGCOMDED_00106 1.03e-90 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
LGCOMDED_00107 1.22e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LGCOMDED_00108 1.11e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
LGCOMDED_00109 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LGCOMDED_00110 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
LGCOMDED_00111 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
LGCOMDED_00112 2.52e-97 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
LGCOMDED_00113 2.3e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LGCOMDED_00114 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LGCOMDED_00115 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGCOMDED_00116 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGCOMDED_00117 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
LGCOMDED_00118 4.47e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LGCOMDED_00119 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGCOMDED_00120 2.1e-214 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
LGCOMDED_00121 6.23e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGCOMDED_00122 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LGCOMDED_00123 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
LGCOMDED_00124 0.0 ylqG - - - - - - -
LGCOMDED_00125 1.67e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGCOMDED_00126 2.83e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LGCOMDED_00127 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LGCOMDED_00128 9.8e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
LGCOMDED_00129 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGCOMDED_00130 9.77e-80 ylqD - - S - - - YlqD protein
LGCOMDED_00131 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
LGCOMDED_00132 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
LGCOMDED_00133 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGCOMDED_00134 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LGCOMDED_00135 1.34e-160 - - - S - - - Phosphotransferase enzyme family
LGCOMDED_00136 2.28e-225 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LGCOMDED_00137 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
LGCOMDED_00138 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LGCOMDED_00139 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGCOMDED_00140 3.5e-167 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
LGCOMDED_00141 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
LGCOMDED_00142 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LGCOMDED_00143 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LGCOMDED_00144 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGCOMDED_00145 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LGCOMDED_00146 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
LGCOMDED_00147 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
LGCOMDED_00148 3.65e-78 yloU - - S - - - protein conserved in bacteria
LGCOMDED_00149 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
LGCOMDED_00150 9.5e-156 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
LGCOMDED_00151 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
LGCOMDED_00152 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LGCOMDED_00153 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
LGCOMDED_00154 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
LGCOMDED_00155 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LGCOMDED_00156 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGCOMDED_00157 3.13e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGCOMDED_00158 4.8e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LGCOMDED_00159 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGCOMDED_00160 5.98e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGCOMDED_00161 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LGCOMDED_00162 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
LGCOMDED_00163 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
LGCOMDED_00164 8.41e-202 yloC - - S - - - stress-induced protein
LGCOMDED_00165 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
LGCOMDED_00166 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
LGCOMDED_00167 7.63e-107 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
LGCOMDED_00168 1.02e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
LGCOMDED_00169 3.56e-186 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LGCOMDED_00170 1.59e-141 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LGCOMDED_00171 1.45e-282 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LGCOMDED_00172 1.04e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
LGCOMDED_00173 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LGCOMDED_00174 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGCOMDED_00175 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LGCOMDED_00176 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LGCOMDED_00177 6.12e-182 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LGCOMDED_00178 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
LGCOMDED_00179 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LGCOMDED_00180 4.86e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LGCOMDED_00181 7.29e-214 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
LGCOMDED_00182 4.31e-295 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
LGCOMDED_00183 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LGCOMDED_00184 3.52e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
LGCOMDED_00185 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGCOMDED_00186 1.58e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
LGCOMDED_00187 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LGCOMDED_00188 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
LGCOMDED_00189 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
LGCOMDED_00190 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
LGCOMDED_00191 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LGCOMDED_00192 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGCOMDED_00193 1.25e-201 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
LGCOMDED_00194 3.58e-51 ylmC - - S - - - sporulation protein
LGCOMDED_00195 9.76e-317 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
LGCOMDED_00196 1.1e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LGCOMDED_00197 1.55e-177 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_00198 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_00199 1.21e-218 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LGCOMDED_00200 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
LGCOMDED_00201 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGCOMDED_00202 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LGCOMDED_00203 1.54e-75 sbp - - S - - - small basic protein
LGCOMDED_00204 1.23e-149 ylxX - - S - - - protein conserved in bacteria
LGCOMDED_00205 6.39e-142 ylxW - - S - - - protein conserved in bacteria
LGCOMDED_00206 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LGCOMDED_00207 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
LGCOMDED_00208 9.03e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGCOMDED_00209 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LGCOMDED_00210 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LGCOMDED_00211 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGCOMDED_00212 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGCOMDED_00213 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
LGCOMDED_00214 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
LGCOMDED_00215 3.42e-68 ftsL - - D - - - Essential cell division protein
LGCOMDED_00216 4.76e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LGCOMDED_00217 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
LGCOMDED_00218 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LGCOMDED_00219 5.12e-211 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGCOMDED_00220 1.33e-115 ylbP - - K - - - n-acetyltransferase
LGCOMDED_00221 4.72e-107 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LGCOMDED_00222 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
LGCOMDED_00223 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
LGCOMDED_00225 5.94e-301 ylbM - - S - - - Belongs to the UPF0348 family
LGCOMDED_00226 4.52e-238 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
LGCOMDED_00227 2.99e-175 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LGCOMDED_00228 6.41e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
LGCOMDED_00229 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LGCOMDED_00230 9.66e-123 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
LGCOMDED_00231 5.1e-51 ylbG - - S - - - UPF0298 protein
LGCOMDED_00232 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
LGCOMDED_00233 1.73e-48 ylbE - - S - - - YlbE-like protein
LGCOMDED_00234 3.24e-89 ylbD - - S - - - Putative coat protein
LGCOMDED_00235 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
LGCOMDED_00236 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
LGCOMDED_00237 1.88e-80 ylbA - - S - - - YugN-like family
LGCOMDED_00238 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
LGCOMDED_00239 5.01e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LGCOMDED_00240 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LGCOMDED_00241 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGCOMDED_00242 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LGCOMDED_00243 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LGCOMDED_00244 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LGCOMDED_00245 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LGCOMDED_00246 3.2e-267 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
LGCOMDED_00247 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
LGCOMDED_00248 1e-218 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LGCOMDED_00249 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGCOMDED_00250 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
LGCOMDED_00251 1.64e-124 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LGCOMDED_00252 8.92e-44 ylaI - - S - - - protein conserved in bacteria
LGCOMDED_00253 4.4e-63 ylaH - - S - - - YlaH-like protein
LGCOMDED_00254 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
LGCOMDED_00255 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
LGCOMDED_00256 9.96e-57 ylaE - - - - - - -
LGCOMDED_00258 2.93e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_00259 1.18e-55 ylaB - - - - - - -
LGCOMDED_00260 0.0 ylaA - - - - - - -
LGCOMDED_00261 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LGCOMDED_00262 8.67e-255 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_00263 9.61e-131 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LGCOMDED_00264 7.9e-246 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
LGCOMDED_00265 3.08e-285 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
LGCOMDED_00266 8.13e-99 yxaI - - S - - - membrane protein domain
LGCOMDED_00267 7.22e-79 - - - S - - - Family of unknown function (DUF5391)
LGCOMDED_00268 1.73e-135 yxaL - - S - - - PQQ-like domain
LGCOMDED_00269 2.09e-16 yxaI - - S - - - membrane protein domain
LGCOMDED_00270 9.79e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LGCOMDED_00271 1.21e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
LGCOMDED_00272 8.38e-193 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LGCOMDED_00274 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
LGCOMDED_00275 3.41e-312 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LGCOMDED_00276 8.67e-64 yxcD - - S - - - Protein of unknown function (DUF2653)
LGCOMDED_00278 1.43e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
LGCOMDED_00279 9.02e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LGCOMDED_00280 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LGCOMDED_00281 1.46e-201 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LGCOMDED_00282 3.52e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LGCOMDED_00283 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LGCOMDED_00284 4.1e-221 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LGCOMDED_00285 2.32e-295 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
LGCOMDED_00286 1.27e-250 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LGCOMDED_00287 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
LGCOMDED_00288 2.67e-192 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LGCOMDED_00289 2.83e-204 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LGCOMDED_00290 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_00291 1.1e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_00292 3.01e-178 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_00293 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LGCOMDED_00294 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
LGCOMDED_00295 7.4e-227 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LGCOMDED_00296 6.79e-91 - - - - - - - -
LGCOMDED_00297 7.57e-28 yxeD - - - - - - -
LGCOMDED_00298 1.04e-08 yxeE - - - - - - -
LGCOMDED_00299 8.64e-22 yxeE - - - - - - -
LGCOMDED_00302 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
LGCOMDED_00303 1.92e-237 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
LGCOMDED_00304 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGCOMDED_00305 2.99e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_00306 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LGCOMDED_00307 1e-146 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LGCOMDED_00308 1.95e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_00309 1.01e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LGCOMDED_00310 2.4e-313 yxeQ - - S - - - MmgE/PrpD family
LGCOMDED_00311 4.46e-255 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
LGCOMDED_00312 1.51e-196 - - - S - - - Domain of Unknown Function (DUF1206)
LGCOMDED_00313 3.5e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LGCOMDED_00314 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LGCOMDED_00315 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGCOMDED_00316 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
LGCOMDED_00317 0.0 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LGCOMDED_00318 3.41e-231 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LGCOMDED_00319 5.49e-300 hutI 3.5.2.7 - Q ko:K01468 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Imidazolone-5-propionate hydrolase
LGCOMDED_00320 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGCOMDED_00321 0.0 hutH 4.3.1.3 - E ko:K01745 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Histidine ammonia-lyase
LGCOMDED_00322 3.11e-100 hutP - - K ko:K09683 - ko00000,ko03000 Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LGCOMDED_00323 0.0 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LGCOMDED_00324 2.51e-95 - - - L - - - NgoFVII restriction endonuclease
LGCOMDED_00325 7.83e-111 - - - S - - - GTP binding
LGCOMDED_00326 4.76e-233 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
LGCOMDED_00327 2.96e-64 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
LGCOMDED_00328 6.24e-36 - - - S - - - Domain of unknown function (DUF5082)
LGCOMDED_00329 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
LGCOMDED_00330 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LGCOMDED_00331 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
LGCOMDED_00332 1.56e-53 - - - - - - - -
LGCOMDED_00333 1.99e-82 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LGCOMDED_00334 2.02e-217 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LGCOMDED_00335 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
LGCOMDED_00336 1.99e-208 yxxF - - EG - - - EamA-like transporter family
LGCOMDED_00337 0.0 wapA - - M - - - COG3209 Rhs family protein
LGCOMDED_00338 3.29e-19 yxiJ - - S - - - YxiJ-like protein
LGCOMDED_00339 6.47e-100 wapA - - M - - - COG3209 Rhs family protein
LGCOMDED_00340 1.27e-69 - - - - - - - -
LGCOMDED_00342 5.06e-175 - - - - - - - -
LGCOMDED_00343 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
LGCOMDED_00344 7.13e-100 - - - - - - - -
LGCOMDED_00345 1.1e-58 - - - - - - - -
LGCOMDED_00346 4.67e-89 yxiG - - - - - - -
LGCOMDED_00347 9.7e-68 yxxG - - - - - - -
LGCOMDED_00348 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
LGCOMDED_00351 1.98e-172 - - - - - - - -
LGCOMDED_00352 1.6e-108 yxiI - - S - - - Protein of unknown function (DUF2716)
LGCOMDED_00353 4.75e-57 yxiJ - - S - - - YxiJ-like protein
LGCOMDED_00356 2.48e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
LGCOMDED_00357 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LGCOMDED_00358 1.8e-290 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
LGCOMDED_00359 3.59e-141 - - - - - - - -
LGCOMDED_00360 1.72e-177 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LGCOMDED_00361 3.06e-184 bglS - - M - - - licheninase activity
LGCOMDED_00362 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LGCOMDED_00363 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LGCOMDED_00364 2.28e-63 yxiS - - - - - - -
LGCOMDED_00365 4.89e-132 - - - T - - - Domain of unknown function (DUF4163)
LGCOMDED_00366 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGCOMDED_00367 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LGCOMDED_00368 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LGCOMDED_00369 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
LGCOMDED_00370 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
LGCOMDED_00371 4.55e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LGCOMDED_00372 1.99e-235 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LGCOMDED_00373 1.32e-57 ywjC - - - - - - -
LGCOMDED_00374 1.51e-121 ywjB - - H - - - RibD C-terminal domain
LGCOMDED_00375 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
LGCOMDED_00376 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGCOMDED_00377 3.42e-158 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
LGCOMDED_00378 7.94e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
LGCOMDED_00379 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
LGCOMDED_00380 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LGCOMDED_00381 8.67e-111 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
LGCOMDED_00382 1.51e-178 ywiC - - S - - - YwiC-like protein
LGCOMDED_00383 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
LGCOMDED_00384 8.44e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LGCOMDED_00385 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
LGCOMDED_00386 6.59e-96 ywiB - - S - - - protein conserved in bacteria
LGCOMDED_00387 3.71e-12 - - - S - - - Bacteriocin subtilosin A
LGCOMDED_00388 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
LGCOMDED_00390 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LGCOMDED_00391 4.86e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
LGCOMDED_00392 5.69e-275 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
LGCOMDED_00393 2.34e-315 - - - L - - - Peptidase, M16
LGCOMDED_00395 2.83e-215 ywhL - - CO - - - amine dehydrogenase activity
LGCOMDED_00396 3.78e-68 ywhL - - CO - - - amine dehydrogenase activity
LGCOMDED_00397 2.29e-153 ywhK - - CO - - - amine dehydrogenase activity
LGCOMDED_00398 5.96e-98 ywhK - - CO - - - amine dehydrogenase activity
LGCOMDED_00399 4.64e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LGCOMDED_00401 7.14e-36 - - - S - - - Aminoacyl-tRNA editing domain
LGCOMDED_00402 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LGCOMDED_00403 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGCOMDED_00404 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LGCOMDED_00405 7.83e-123 ywhD - - S - - - YwhD family
LGCOMDED_00406 3.29e-154 ywhC - - S - - - Peptidase family M50
LGCOMDED_00407 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
LGCOMDED_00408 1.76e-94 ywhA - - K - - - Transcriptional regulator
LGCOMDED_00409 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LGCOMDED_00411 1.45e-298 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
LGCOMDED_00412 3.15e-103 yffB - - K - - - Transcriptional regulator
LGCOMDED_00413 8.53e-115 ywgA - - - ko:K09388 - ko00000 -
LGCOMDED_00414 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
LGCOMDED_00415 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
LGCOMDED_00416 8.85e-142 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
LGCOMDED_00417 4.83e-199 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
LGCOMDED_00418 2.15e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LGCOMDED_00419 3.07e-208 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_00420 3.93e-223 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
LGCOMDED_00421 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
LGCOMDED_00422 8.75e-170 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
LGCOMDED_00423 3.03e-101 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LGCOMDED_00424 1.1e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_00425 3.31e-155 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LGCOMDED_00426 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LGCOMDED_00427 1.04e-272 ywfA - - EGP - - - -transporter
LGCOMDED_00428 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LGCOMDED_00429 0.0 rocB - - E - - - arginine degradation protein
LGCOMDED_00430 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LGCOMDED_00431 2.29e-261 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LGCOMDED_00432 3.7e-101 - - - - - - - -
LGCOMDED_00433 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
LGCOMDED_00434 1.92e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LGCOMDED_00435 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LGCOMDED_00436 2.5e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGCOMDED_00437 8.14e-240 spsG - - M - - - Spore Coat
LGCOMDED_00438 8.63e-165 spsF - - M ko:K07257 - ko00000 Spore Coat
LGCOMDED_00439 7.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
LGCOMDED_00440 8.17e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
LGCOMDED_00441 2.07e-281 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
LGCOMDED_00442 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
LGCOMDED_00443 8.08e-187 spsA - - M - - - Spore Coat
LGCOMDED_00444 7.3e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LGCOMDED_00445 6.48e-78 ywdK - - S - - - small membrane protein
LGCOMDED_00446 1.86e-303 ywdJ - - F - - - Xanthine uracil
LGCOMDED_00447 9.23e-65 ywdI - - S - - - Family of unknown function (DUF5327)
LGCOMDED_00448 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LGCOMDED_00449 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LGCOMDED_00450 1.34e-191 ywdF - - S - - - Glycosyltransferase like family 2
LGCOMDED_00452 1.19e-143 ywdD - - - - - - -
LGCOMDED_00453 6.52e-75 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
LGCOMDED_00454 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LGCOMDED_00455 6.19e-39 ywdA - - - - - - -
LGCOMDED_00456 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
LGCOMDED_00457 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_00458 3.96e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
LGCOMDED_00459 2.13e-192 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LGCOMDED_00462 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LGCOMDED_00463 1.64e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGCOMDED_00464 9.4e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
LGCOMDED_00465 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
LGCOMDED_00466 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
LGCOMDED_00467 8.95e-60 yfhJ - - S - - - WVELL protein
LGCOMDED_00468 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
LGCOMDED_00469 4.05e-267 yfhI - - EGP - - - -transporter
LGCOMDED_00471 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
LGCOMDED_00472 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
LGCOMDED_00473 2.56e-218 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
LGCOMDED_00474 8.86e-35 yfhD - - S - - - YfhD-like protein
LGCOMDED_00475 2.87e-138 yfhC - - C - - - nitroreductase
LGCOMDED_00476 6e-212 yfhB - - S - - - PhzF family
LGCOMDED_00477 3.49e-227 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_00478 1.04e-223 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_00479 9.03e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LGCOMDED_00480 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LGCOMDED_00481 2.11e-103 yfiV - - K - - - transcriptional
LGCOMDED_00482 0.0 yfiU - - EGP - - - the major facilitator superfamily
LGCOMDED_00483 2.31e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
LGCOMDED_00484 4.25e-249 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LGCOMDED_00485 4.55e-127 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LGCOMDED_00486 1.89e-128 padR - - K - - - transcriptional
LGCOMDED_00487 2.13e-66 - - - J - - - Acetyltransferase (GNAT) domain
LGCOMDED_00488 1.7e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LGCOMDED_00489 6.49e-268 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LGCOMDED_00490 6.48e-216 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_00491 6.07e-146 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
LGCOMDED_00492 2.94e-273 baeS - - T - - - Histidine kinase
LGCOMDED_00494 6.76e-291 - - - S - - - Oxidoreductase
LGCOMDED_00495 2.23e-233 - - - G - - - Xylose isomerase
LGCOMDED_00496 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LGCOMDED_00497 5.61e-223 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
LGCOMDED_00498 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
LGCOMDED_00499 3.34e-83 yfiD3 - - S - - - DoxX
LGCOMDED_00500 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LGCOMDED_00501 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
LGCOMDED_00502 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_00503 3.54e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
LGCOMDED_00504 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LGCOMDED_00505 9.28e-60 yfjA - - S - - - Belongs to the WXG100 family
LGCOMDED_00506 1.71e-266 yfjB - - - - - - -
LGCOMDED_00507 2.5e-185 yfjC - - - - - - -
LGCOMDED_00508 6.08e-131 yfjD - - S - - - Family of unknown function (DUF5381)
LGCOMDED_00509 1.5e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
LGCOMDED_00510 8.16e-36 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
LGCOMDED_00511 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
LGCOMDED_00512 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LGCOMDED_00513 5.21e-259 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LGCOMDED_00514 9.2e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LGCOMDED_00515 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LGCOMDED_00517 7.85e-110 yfjM - - S - - - Psort location Cytoplasmic, score
LGCOMDED_00518 5.07e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGCOMDED_00519 4.32e-59 - - - S - - - YfzA-like protein
LGCOMDED_00520 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGCOMDED_00521 2.76e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LGCOMDED_00522 2.24e-236 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
LGCOMDED_00523 3.25e-192 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LGCOMDED_00524 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
LGCOMDED_00525 3.26e-36 yfjT - - - - - - -
LGCOMDED_00526 1.76e-283 yfkA - - S - - - YfkB-like domain
LGCOMDED_00527 1.81e-190 yfkC - - M - - - Mechanosensitive ion channel
LGCOMDED_00528 1.06e-188 yfkD - - S - - - YfkD-like protein
LGCOMDED_00529 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
LGCOMDED_00530 4.48e-277 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LGCOMDED_00531 2.74e-11 - - - - - - - -
LGCOMDED_00532 1.37e-183 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
LGCOMDED_00533 1.03e-66 yfkI - - S - - - gas vesicle protein
LGCOMDED_00534 1.39e-102 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LGCOMDED_00535 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
LGCOMDED_00536 1.03e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LGCOMDED_00537 7.47e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LGCOMDED_00538 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LGCOMDED_00539 2.93e-158 frp - - C - - - nitroreductase
LGCOMDED_00540 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
LGCOMDED_00541 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
LGCOMDED_00542 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_00543 1.95e-142 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LGCOMDED_00544 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
LGCOMDED_00545 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LGCOMDED_00546 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LGCOMDED_00547 7.72e-177 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LGCOMDED_00548 2.1e-65 yflH - - S - - - Protein of unknown function (DUF3243)
LGCOMDED_00549 6.9e-27 yflI - - - - - - -
LGCOMDED_00550 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
LGCOMDED_00551 6.9e-157 yflK - - S - - - protein conserved in bacteria
LGCOMDED_00552 3.48e-58 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
LGCOMDED_00553 6.53e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LGCOMDED_00554 2.82e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LGCOMDED_00555 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LGCOMDED_00556 6.6e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
LGCOMDED_00557 1.33e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
LGCOMDED_00558 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LGCOMDED_00559 2.36e-304 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
LGCOMDED_00560 2.01e-306 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
LGCOMDED_00561 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
LGCOMDED_00562 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
LGCOMDED_00563 1.53e-216 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LGCOMDED_00564 4.72e-220 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_00565 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_00566 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LGCOMDED_00567 2e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
LGCOMDED_00568 1.23e-105 - - - S - - - Protein of unknown function (DUF2690)
LGCOMDED_00569 1.13e-29 yjfB - - S - - - Putative motility protein
LGCOMDED_00570 4.94e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
LGCOMDED_00571 2.67e-57 yjgA - - T - - - Protein of unknown function (DUF2809)
LGCOMDED_00572 6.76e-131 yjgB - - S - - - Domain of unknown function (DUF4309)
LGCOMDED_00573 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LGCOMDED_00574 2.19e-193 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LGCOMDED_00575 1.84e-85 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LGCOMDED_00576 9.24e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
LGCOMDED_00579 5.04e-87 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
LGCOMDED_00581 5.52e-285 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LGCOMDED_00582 2.4e-277 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LGCOMDED_00583 1.11e-41 - - - - - - - -
LGCOMDED_00584 1.01e-185 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LGCOMDED_00585 1.05e-154 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
LGCOMDED_00586 1.14e-174 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
LGCOMDED_00587 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
LGCOMDED_00588 2.87e-117 yjlB - - S - - - Cupin domain
LGCOMDED_00589 3.98e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
LGCOMDED_00590 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LGCOMDED_00591 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
LGCOMDED_00592 7.52e-315 - - - G ko:K03292 - ko00000 symporter YjmB
LGCOMDED_00593 2.08e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
LGCOMDED_00594 3.31e-239 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
LGCOMDED_00595 1.53e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
LGCOMDED_00596 1.34e-196 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_00597 1.37e-289 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
LGCOMDED_00598 2.23e-234 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
LGCOMDED_00599 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
LGCOMDED_00600 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LGCOMDED_00601 9.2e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
LGCOMDED_00602 2.71e-103 yjoA - - S - - - DinB family
LGCOMDED_00603 2.38e-311 VCP - - O - - - AAA domain (dynein-related subfamily)
LGCOMDED_00604 1.6e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LGCOMDED_00606 1.21e-53 - - - S - - - YCII-related domain
LGCOMDED_00607 1.26e-216 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LGCOMDED_00608 5.74e-80 yjqA - - S - - - Bacterial PH domain
LGCOMDED_00609 2.74e-139 yjqB - - S - - - Pfam:DUF867
LGCOMDED_00610 1.3e-203 yjqC - - P ko:K07217 - ko00000 Catalase
LGCOMDED_00611 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
LGCOMDED_00612 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
LGCOMDED_00614 7.53e-203 xkdB - - K - - - sequence-specific DNA binding
LGCOMDED_00615 2.05e-139 xkdC - - L - - - Bacterial dnaA protein
LGCOMDED_00619 5.95e-112 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LGCOMDED_00620 4.78e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
LGCOMDED_00621 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
LGCOMDED_00622 0.0 yqbA - - S - - - portal protein
LGCOMDED_00623 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
LGCOMDED_00624 3.91e-217 xkdG - - S - - - Phage capsid family
LGCOMDED_00625 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
LGCOMDED_00626 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
LGCOMDED_00627 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
LGCOMDED_00628 2.36e-100 xkdJ - - - - - - -
LGCOMDED_00629 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
LGCOMDED_00630 6.01e-99 xkdM - - S - - - Phage tail tube protein
LGCOMDED_00631 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LGCOMDED_00632 0.0 xkdO - - L - - - Transglycosylase SLT domain
LGCOMDED_00633 2.49e-149 xkdP - - S - - - Lysin motif
LGCOMDED_00634 9.42e-232 xkdQ - - G - - - NLP P60 protein
LGCOMDED_00635 1.24e-52 xkdR - - S - - - Protein of unknown function (DUF2577)
LGCOMDED_00636 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
LGCOMDED_00637 3.6e-243 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LGCOMDED_00638 6.25e-132 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LGCOMDED_00639 2.56e-55 - - - - - - - -
LGCOMDED_00640 5.43e-164 - - - - - - - -
LGCOMDED_00642 1.82e-12 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
LGCOMDED_00643 2.71e-46 xhlA - - S - - - Haemolysin XhlA
LGCOMDED_00644 8.12e-53 xhlB - - S - - - SPP1 phage holin
LGCOMDED_00645 3.73e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LGCOMDED_00646 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
LGCOMDED_00647 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
LGCOMDED_00648 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
LGCOMDED_00649 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
LGCOMDED_00650 2.36e-305 steT - - E ko:K03294 - ko00000 amino acid
LGCOMDED_00651 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LGCOMDED_00652 7.25e-293 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGCOMDED_00653 2.19e-120 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGCOMDED_00654 5.21e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LGCOMDED_00656 1.92e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGCOMDED_00657 3.2e-176 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
LGCOMDED_00658 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
LGCOMDED_00659 4.52e-198 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGCOMDED_00660 3.02e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGCOMDED_00661 6.67e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_00662 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LGCOMDED_00664 2.26e-223 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
LGCOMDED_00665 1.09e-253 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LGCOMDED_00666 1.2e-208 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LGCOMDED_00667 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_00668 9.43e-260 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
LGCOMDED_00669 2.95e-204 ykgA - - E - - - Amidinotransferase
LGCOMDED_00670 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
LGCOMDED_00671 3.32e-283 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGCOMDED_00672 5.45e-13 - - - - - - - -
LGCOMDED_00673 3.25e-166 ykjA - - S - - - Protein of unknown function (DUF421)
LGCOMDED_00674 9.11e-128 ykkA - - S - - - Protein of unknown function (DUF664)
LGCOMDED_00675 8.47e-127 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LGCOMDED_00676 7.34e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
LGCOMDED_00677 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
LGCOMDED_00678 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LGCOMDED_00679 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LGCOMDED_00680 6.52e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGCOMDED_00682 1.97e-92 ohrA - - O - - - Organic hydroperoxide resistance protein
LGCOMDED_00683 1.21e-98 ohrR - - K - - - COG1846 Transcriptional regulators
LGCOMDED_00684 2.34e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
LGCOMDED_00685 1.63e-114 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
LGCOMDED_00687 8.2e-48 ydjO - - S - - - Cold-inducible protein YdjO
LGCOMDED_00688 2.95e-201 - - - I - - - Alpha/beta hydrolase family
LGCOMDED_00689 1.68e-227 yeaA - - S - - - Protein of unknown function (DUF4003)
LGCOMDED_00690 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
LGCOMDED_00691 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_00692 4.82e-196 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGCOMDED_00693 2.79e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
LGCOMDED_00694 1.07e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LGCOMDED_00695 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
LGCOMDED_00696 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
LGCOMDED_00697 7.14e-117 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_00698 0.0 - - - S - - - Domain of unknown function (DUF4179)
LGCOMDED_00699 1.33e-280 pbuG - - S ko:K06901 - ko00000,ko02000 permease
LGCOMDED_00700 7.95e-163 yebC - - M - - - Membrane
LGCOMDED_00702 2.66e-120 yebE - - S - - - UPF0316 protein
LGCOMDED_00703 3.13e-38 yebG - - S - - - NETI protein
LGCOMDED_00704 8.91e-106 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGCOMDED_00705 3.66e-275 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGCOMDED_00706 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGCOMDED_00707 2.78e-166 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
LGCOMDED_00708 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGCOMDED_00709 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGCOMDED_00710 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGCOMDED_00711 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGCOMDED_00712 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
LGCOMDED_00713 1.26e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGCOMDED_00714 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
LGCOMDED_00715 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
LGCOMDED_00716 1.11e-95 - - - K - - - helix_turn_helix ASNC type
LGCOMDED_00717 5.35e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
LGCOMDED_00718 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
LGCOMDED_00719 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
LGCOMDED_00720 1.07e-240 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
LGCOMDED_00721 7.62e-68 yerC - - S - - - protein conserved in bacteria
LGCOMDED_00722 4.08e-249 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LGCOMDED_00723 4.95e-39 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
LGCOMDED_00725 3.15e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LGCOMDED_00726 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
LGCOMDED_00727 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGCOMDED_00728 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
LGCOMDED_00729 5.16e-252 yerI - - S - - - homoserine kinase type II (protein kinase fold)
LGCOMDED_00730 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
LGCOMDED_00731 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGCOMDED_00732 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGCOMDED_00733 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LGCOMDED_00734 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGCOMDED_00735 6.67e-187 yerO - - K - - - Transcriptional regulator
LGCOMDED_00736 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGCOMDED_00737 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LGCOMDED_00738 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGCOMDED_00740 5.6e-125 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LGCOMDED_00742 4e-40 - - - S - - - Colicin immunity protein / pyocin immunity protein
LGCOMDED_00744 1.73e-108 - - - S - - - Protein of unknown function, DUF600
LGCOMDED_00745 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LGCOMDED_00746 2.38e-121 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
LGCOMDED_00747 2.16e-70 - 3.4.24.40 - CO ko:K01406 ko01503,map01503 ko00000,ko00001,ko01000,ko01002 amine dehydrogenase activity
LGCOMDED_00748 1.73e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
LGCOMDED_00750 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
LGCOMDED_00752 9.52e-128 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_00753 7.67e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
LGCOMDED_00754 9.4e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
LGCOMDED_00755 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
LGCOMDED_00756 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
LGCOMDED_00758 7.03e-130 yesL - - S - - - Protein of unknown function, DUF624
LGCOMDED_00759 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_00760 1.82e-255 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
LGCOMDED_00761 3.39e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
LGCOMDED_00762 8.23e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LGCOMDED_00763 8.48e-209 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LGCOMDED_00764 2.29e-253 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
LGCOMDED_00765 0.0 yesS - - K - - - Transcriptional regulator
LGCOMDED_00766 3.83e-166 - - - E - - - GDSL-like Lipase/Acylhydrolase
LGCOMDED_00767 4.88e-161 yesU - - S - - - Domain of unknown function (DUF1961)
LGCOMDED_00768 3.17e-142 - - - S - - - Protein of unknown function, DUF624
LGCOMDED_00769 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LGCOMDED_00770 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
LGCOMDED_00771 6.17e-158 - - - E - - - GDSL-like Lipase/Acylhydrolase
LGCOMDED_00772 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
LGCOMDED_00773 0.0 yetA - - - - - - -
LGCOMDED_00774 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LGCOMDED_00775 2.39e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LGCOMDED_00776 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LGCOMDED_00777 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LGCOMDED_00778 7.07e-155 yetF - - S - - - membrane
LGCOMDED_00779 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LGCOMDED_00780 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
LGCOMDED_00781 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGCOMDED_00782 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LGCOMDED_00783 5.11e-49 ydaS - - S - - - membrane
LGCOMDED_00784 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
LGCOMDED_00785 6.49e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LGCOMDED_00786 3.33e-77 gtcA - - S - - - GtrA-like protein
LGCOMDED_00787 1.1e-154 ywcC - - K - - - transcriptional regulator
LGCOMDED_00789 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
LGCOMDED_00790 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGCOMDED_00791 3.25e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LGCOMDED_00792 4.22e-306 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
LGCOMDED_00793 1.98e-245 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
LGCOMDED_00794 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
LGCOMDED_00795 2.03e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LGCOMDED_00796 5.16e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LGCOMDED_00797 2.7e-203 ywbI - - K - - - Transcriptional regulator
LGCOMDED_00798 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LGCOMDED_00799 1.21e-143 ywbG - - M - - - effector of murein hydrolase
LGCOMDED_00800 5.87e-275 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
LGCOMDED_00801 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
LGCOMDED_00802 4.67e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
LGCOMDED_00803 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
LGCOMDED_00804 5.66e-158 ywbB - - S - - - Protein of unknown function (DUF2711)
LGCOMDED_00805 3.5e-309 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LGCOMDED_00806 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LGCOMDED_00807 5.64e-310 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_00808 9.07e-196 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
LGCOMDED_00809 6.53e-217 gspA - - M - - - General stress
LGCOMDED_00810 5.31e-51 ywaF - - S - - - Integral membrane protein
LGCOMDED_00811 3.33e-82 ywaF - - S - - - Integral membrane protein
LGCOMDED_00812 2.15e-115 ywaE - - K - - - Transcriptional regulator
LGCOMDED_00813 4.48e-297 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LGCOMDED_00814 3.65e-316 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
LGCOMDED_00815 1.08e-115 - - - K - - - Helix-turn-helix XRE-family like proteins
LGCOMDED_00816 5.58e-64 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
LGCOMDED_00817 4.57e-164 - - - EGP - - - Permeases of the major facilitator superfamily
LGCOMDED_00818 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
LGCOMDED_00819 5.7e-210 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
LGCOMDED_00820 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LGCOMDED_00821 2.29e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
LGCOMDED_00822 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LGCOMDED_00823 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LGCOMDED_00824 9.6e-20 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_00825 7.82e-119 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_00826 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LGCOMDED_00827 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LGCOMDED_00828 1.3e-49 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_00829 3.82e-157 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LGCOMDED_00830 4.25e-136 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LGCOMDED_00831 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
LGCOMDED_00832 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
LGCOMDED_00833 8.94e-28 yxzF - - - - - - -
LGCOMDED_00834 1.54e-143 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
LGCOMDED_00835 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LGCOMDED_00836 1.64e-248 yxlH - - EGP - - - Major Facilitator Superfamily
LGCOMDED_00837 2.98e-126 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LGCOMDED_00838 1.17e-188 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_00839 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
LGCOMDED_00840 6.66e-39 - - - - - - - -
LGCOMDED_00841 1.58e-52 yxlC - - S - - - Family of unknown function (DUF5345)
LGCOMDED_00842 1.06e-123 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_00843 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
LGCOMDED_00844 2.09e-123 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGCOMDED_00845 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
LGCOMDED_00846 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
LGCOMDED_00847 9.56e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
LGCOMDED_00848 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LGCOMDED_00849 3.8e-308 cimH - - C - - - COG3493 Na citrate symporter
LGCOMDED_00850 0.0 - - - O - - - Peptidase family M48
LGCOMDED_00852 6.16e-198 yxkH - - G - - - Polysaccharide deacetylase
LGCOMDED_00853 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_00854 1.12e-209 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
LGCOMDED_00855 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LGCOMDED_00856 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGCOMDED_00857 2.35e-98 yxkC - - S - - - Domain of unknown function (DUF4352)
LGCOMDED_00858 4.26e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
LGCOMDED_00859 7.69e-100 - - - S - - - Protein of unknown function (DUF1453)
LGCOMDED_00860 1.37e-258 - - - T - - - Signal transduction histidine kinase
LGCOMDED_00861 7.4e-146 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
LGCOMDED_00862 7.76e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
LGCOMDED_00865 2.88e-111 yxjI - - S - - - LURP-one-related
LGCOMDED_00866 1.5e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LGCOMDED_00867 6.32e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
LGCOMDED_00868 1.41e-115 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LGCOMDED_00869 7.78e-33 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LGCOMDED_00870 4.86e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LGCOMDED_00871 7.71e-167 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGCOMDED_00872 8.12e-32 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LGCOMDED_00873 3.25e-269 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
LGCOMDED_00874 3.59e-203 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
LGCOMDED_00875 1.45e-199 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_00876 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LGCOMDED_00877 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
LGCOMDED_00878 1.14e-124 - - - L - - - Integrase
LGCOMDED_00880 7.14e-128 yoeB - - S - - - IseA DL-endopeptidase inhibitor
LGCOMDED_00881 9.8e-313 yoeA - - V - - - MATE efflux family protein
LGCOMDED_00882 1.11e-239 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
LGCOMDED_00883 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LGCOMDED_00884 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LGCOMDED_00885 1.17e-147 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LGCOMDED_00886 2.19e-143 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LGCOMDED_00887 3.06e-185 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LGCOMDED_00888 8.57e-267 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
LGCOMDED_00889 2.12e-84 yngL - - S - - - Protein of unknown function (DUF1360)
LGCOMDED_00890 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
LGCOMDED_00891 7.28e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LGCOMDED_00892 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LGCOMDED_00893 0.0 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
LGCOMDED_00894 1.98e-40 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
LGCOMDED_00895 1.36e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
LGCOMDED_00896 8.22e-173 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
LGCOMDED_00897 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LGCOMDED_00898 2.12e-295 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
LGCOMDED_00899 2.01e-134 yngC - - S - - - membrane-associated protein
LGCOMDED_00900 2.74e-210 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LGCOMDED_00901 1.04e-98 yngA - - S - - - membrane
LGCOMDED_00902 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LGCOMDED_00903 2.08e-171 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
LGCOMDED_00904 6.96e-113 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
LGCOMDED_00906 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
LGCOMDED_00907 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LGCOMDED_00908 8.74e-75 ynfC - - - - - - -
LGCOMDED_00909 1.82e-18 - - - - - - - -
LGCOMDED_00910 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LGCOMDED_00911 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LGCOMDED_00912 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
LGCOMDED_00913 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LGCOMDED_00914 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
LGCOMDED_00915 5.48e-70 yneQ - - - - - - -
LGCOMDED_00916 1.4e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
LGCOMDED_00917 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
LGCOMDED_00919 9.26e-10 - - - S - - - Fur-regulated basic protein B
LGCOMDED_00920 3.74e-120 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGCOMDED_00921 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGCOMDED_00922 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
LGCOMDED_00923 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
LGCOMDED_00924 5.77e-85 cotM - - O ko:K06335 - ko00000 Spore coat protein
LGCOMDED_00925 3.97e-97 yneK - - S - - - Protein of unknown function (DUF2621)
LGCOMDED_00926 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
LGCOMDED_00927 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
LGCOMDED_00928 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
LGCOMDED_00929 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
LGCOMDED_00930 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
LGCOMDED_00931 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
LGCOMDED_00932 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGCOMDED_00933 1.15e-43 ynzC - - S - - - UPF0291 protein
LGCOMDED_00934 2.68e-143 yneB - - L - - - resolvase
LGCOMDED_00935 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LGCOMDED_00936 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGCOMDED_00937 1.22e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LGCOMDED_00938 8.65e-119 yndM - - S - - - Protein of unknown function (DUF2512)
LGCOMDED_00939 5.4e-174 yndL - - S - - - Replication protein
LGCOMDED_00941 0.0 yndJ - - S - - - YndJ-like protein
LGCOMDED_00942 2.36e-146 - - - S - - - Domain of unknown function (DUF4166)
LGCOMDED_00943 5.29e-198 yndG - - S - - - DoxX-like family
LGCOMDED_00944 6.51e-241 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
LGCOMDED_00945 2.18e-247 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
LGCOMDED_00946 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LGCOMDED_00949 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
LGCOMDED_00950 2.59e-70 - - - - - - - -
LGCOMDED_00951 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
LGCOMDED_00954 9.38e-162 - - - S - - - Domain of unknown function, YrpD
LGCOMDED_00956 8.27e-40 - - - - - - - -
LGCOMDED_00957 1.59e-209 - - - S - - - Thymidylate synthase
LGCOMDED_00960 7.54e-22 - - - - - - - -
LGCOMDED_00961 3.01e-102 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LGCOMDED_00962 1.15e-108 - - - S - - - Protein of unknown function (DUF2691)
LGCOMDED_00963 1.05e-276 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGCOMDED_00964 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LGCOMDED_00965 2.06e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LGCOMDED_00966 0.0 - - - L - - - ATPase involved in DNA repair
LGCOMDED_00967 9.72e-11 - - - - - - - -
LGCOMDED_00968 6.42e-301 - - - T - - - Putative serine esterase (DUF676)
LGCOMDED_00969 1.23e-212 - - - - - - - -
LGCOMDED_00970 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGCOMDED_00972 2.13e-36 - - - - - - - -
LGCOMDED_00973 2.03e-294 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LGCOMDED_00975 5.22e-28 yycQ - - S - - - Protein of unknown function (DUF2651)
LGCOMDED_00976 1.99e-262 yycP - - - - - - -
LGCOMDED_00977 9.3e-167 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LGCOMDED_00978 4.89e-108 yycN - - K - - - Acetyltransferase
LGCOMDED_00979 1.23e-238 - - - S - - - aspartate phosphatase
LGCOMDED_00981 5.33e-212 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
LGCOMDED_00982 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LGCOMDED_00983 9.1e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
LGCOMDED_00984 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LGCOMDED_00985 1.01e-273 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGCOMDED_00986 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LGCOMDED_00987 4.01e-199 yycI - - S - - - protein conserved in bacteria
LGCOMDED_00988 0.0 yycH - - S - - - protein conserved in bacteria
LGCOMDED_00989 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_00990 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_00995 1.29e-314 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGCOMDED_00996 3.81e-71 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LGCOMDED_00997 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LGCOMDED_00998 3.48e-40 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LGCOMDED_01000 1.89e-22 yycC - - K - - - YycC-like protein
LGCOMDED_01001 1.4e-281 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
LGCOMDED_01002 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGCOMDED_01003 9.16e-95 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LGCOMDED_01004 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
LGCOMDED_01005 1.5e-204 yybS - - S - - - membrane
LGCOMDED_01007 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
LGCOMDED_01008 1.3e-87 yybR - - K - - - Transcriptional regulator
LGCOMDED_01009 1.4e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
LGCOMDED_01010 2.07e-43 - - - - - - - -
LGCOMDED_01011 7e-36 - - - - - - - -
LGCOMDED_01013 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_01014 5.1e-141 - - - K - - - TipAS antibiotic-recognition domain
LGCOMDED_01015 4.62e-180 - - - - - - - -
LGCOMDED_01016 5.02e-87 - - - S - - - SnoaL-like domain
LGCOMDED_01017 1.09e-159 yybG - - S - - - Pentapeptide repeat-containing protein
LGCOMDED_01018 4.5e-129 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_01019 3.29e-102 - - - S - - - Metallo-beta-lactamase superfamily
LGCOMDED_01020 1.85e-99 yybA - - K - - - transcriptional
LGCOMDED_01021 4.18e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
LGCOMDED_01022 1.01e-123 yyaS - - S ko:K07149 - ko00000 Membrane
LGCOMDED_01023 3.86e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
LGCOMDED_01024 7.41e-86 - - - S - - - YjbR
LGCOMDED_01025 7.09e-136 yyaP - - H - - - RibD C-terminal domain
LGCOMDED_01026 7.74e-312 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_01027 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
LGCOMDED_01028 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
LGCOMDED_01029 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
LGCOMDED_01030 6.07e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
LGCOMDED_01031 3.3e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LGCOMDED_01032 4.83e-227 ccpB - - K - - - Transcriptional regulator
LGCOMDED_01033 9.83e-186 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
LGCOMDED_01034 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGCOMDED_01035 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LGCOMDED_01036 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
LGCOMDED_01037 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LGCOMDED_01038 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LGCOMDED_01039 7.41e-45 yyzM - - S - - - protein conserved in bacteria
LGCOMDED_01040 5.34e-227 yyaD - - S - - - Membrane
LGCOMDED_01041 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
LGCOMDED_01042 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
LGCOMDED_01043 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
LGCOMDED_01044 8.9e-96 - - - S - - - Bacterial PH domain
LGCOMDED_01045 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LGCOMDED_01046 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LGCOMDED_01047 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LGCOMDED_01048 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGCOMDED_01049 2.14e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
LGCOMDED_01050 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LGCOMDED_01051 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LGCOMDED_01052 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGCOMDED_01053 1.15e-261 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LGCOMDED_01054 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
LGCOMDED_01055 3.73e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LGCOMDED_01056 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
LGCOMDED_01057 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGCOMDED_01058 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGCOMDED_01059 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LGCOMDED_01060 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
LGCOMDED_01061 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LGCOMDED_01062 1.27e-59 ysdA - - S - - - Membrane
LGCOMDED_01063 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
LGCOMDED_01064 1.77e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
LGCOMDED_01065 4.56e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
LGCOMDED_01066 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
LGCOMDED_01067 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
LGCOMDED_01068 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LGCOMDED_01069 7.07e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
LGCOMDED_01070 1.24e-280 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LGCOMDED_01071 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LGCOMDED_01072 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
LGCOMDED_01073 7.39e-191 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
LGCOMDED_01074 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
LGCOMDED_01075 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
LGCOMDED_01077 5.13e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
LGCOMDED_01078 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
LGCOMDED_01079 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
LGCOMDED_01080 1.24e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
LGCOMDED_01081 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
LGCOMDED_01082 1.22e-168 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGCOMDED_01083 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LGCOMDED_01084 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LGCOMDED_01085 1.47e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGCOMDED_01086 2.45e-53 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGCOMDED_01087 1.55e-111 yshB - - S - - - membrane protein, required for colicin V production
LGCOMDED_01088 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
LGCOMDED_01089 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LGCOMDED_01090 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
LGCOMDED_01091 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LGCOMDED_01092 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_01093 1.81e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
LGCOMDED_01094 1.74e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
LGCOMDED_01095 1.18e-225 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
LGCOMDED_01096 3.03e-305 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
LGCOMDED_01097 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
LGCOMDED_01098 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LGCOMDED_01099 3.79e-273 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LGCOMDED_01100 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
LGCOMDED_01101 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
LGCOMDED_01102 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LGCOMDED_01103 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
LGCOMDED_01104 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
LGCOMDED_01105 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_01106 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_01107 3.55e-195 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LGCOMDED_01108 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
LGCOMDED_01109 3.53e-171 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGCOMDED_01110 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGCOMDED_01111 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
LGCOMDED_01113 9.64e-183 ysnF - - S - - - protein conserved in bacteria
LGCOMDED_01114 1.25e-102 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
LGCOMDED_01115 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LGCOMDED_01116 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
LGCOMDED_01117 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LGCOMDED_01118 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LGCOMDED_01119 7.43e-256 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LGCOMDED_01120 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGCOMDED_01121 7.31e-148 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGCOMDED_01122 1.11e-239 ysoA - - H - - - Tetratricopeptide repeat
LGCOMDED_01123 2.96e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LGCOMDED_01124 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGCOMDED_01125 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
LGCOMDED_01126 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGCOMDED_01127 6.25e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
LGCOMDED_01128 8.23e-117 ysxD - - - - - - -
LGCOMDED_01129 1.92e-315 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGCOMDED_01130 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
LGCOMDED_01131 5.37e-221 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LGCOMDED_01132 5.87e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
LGCOMDED_01133 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
LGCOMDED_01134 1.75e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LGCOMDED_01135 4.44e-205 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
LGCOMDED_01136 1.79e-84 ydjM - - M - - - Lytic transglycolase
LGCOMDED_01137 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
LGCOMDED_01138 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LGCOMDED_01139 1.91e-33 - - - S - - - Ion transport 2 domain protein
LGCOMDED_01140 4.11e-183 - - - S - - - Ion transport 2 domain protein
LGCOMDED_01141 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
LGCOMDED_01142 3.21e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
LGCOMDED_01143 1.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGCOMDED_01144 1.54e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
LGCOMDED_01145 2.86e-219 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
LGCOMDED_01146 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
LGCOMDED_01147 1.76e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
LGCOMDED_01148 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
LGCOMDED_01149 8.92e-52 - - - - - - - -
LGCOMDED_01150 7.41e-72 - - - - - - - -
LGCOMDED_01152 1.48e-73 - - - - - - - -
LGCOMDED_01156 2.85e-113 - - - E - - - Zn peptidase
LGCOMDED_01158 1.12e-36 - - - K - - - Helix-turn-helix domain
LGCOMDED_01161 2.18e-79 - - - M - - - NLP P60 protein
LGCOMDED_01163 2.02e-135 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LGCOMDED_01164 1.58e-41 xhlB - - S - - - SPP1 phage holin
LGCOMDED_01165 1.95e-37 xhlA - - S - - - Haemolysin XhlA
LGCOMDED_01166 2.89e-17 xkdX - - - - - - -
LGCOMDED_01168 2.57e-50 - - - - - - - -
LGCOMDED_01169 3.01e-79 - - - - - - - -
LGCOMDED_01170 1.39e-132 - - - S - - - homolog of phage Mu protein gp47
LGCOMDED_01171 2.25e-30 - - - S - - - Protein of unknown function (DUF2634)
LGCOMDED_01173 3.69e-111 - - - - - - - -
LGCOMDED_01174 1.86e-40 - - - - - - - -
LGCOMDED_01175 6.22e-47 - - - M - - - LysM domain
LGCOMDED_01176 7.39e-173 - - - N - - - phage tail tape measure protein
LGCOMDED_01177 2.62e-22 - - - - - - - -
LGCOMDED_01178 8.46e-46 - - - - - - - -
LGCOMDED_01179 1.45e-129 - - - S - - - Protein of unknown function (DUF3383)
LGCOMDED_01180 8.93e-42 - - - - - - - -
LGCOMDED_01182 2.31e-59 - - - - - - - -
LGCOMDED_01184 1.57e-38 - - - S - - - Phage Mu protein F like protein
LGCOMDED_01186 1.31e-143 - - - S - - - Phage capsid family
LGCOMDED_01187 7.15e-87 - - - S - - - Domain of unknown function (DUF4355)
LGCOMDED_01188 3.19e-199 - - - S - - - Phage portal protein, SPP1 Gp6-like
LGCOMDED_01189 3.12e-234 - - - S - - - Terminase-like family
LGCOMDED_01190 6.85e-112 yqaS - - L - - - DNA packaging
LGCOMDED_01193 4.27e-15 - - - - - - - -
LGCOMDED_01194 2.95e-23 - - - K - - - Transcriptional regulator
LGCOMDED_01196 3.72e-91 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LGCOMDED_01203 7.2e-53 - - - S - - - dUTPase
LGCOMDED_01206 6.43e-37 yqaO - - S - - - Phage-like element PBSX protein XtrA
LGCOMDED_01208 1.83e-70 - - - S - - - Protein of unknown function (DUF1064)
LGCOMDED_01211 9.46e-53 yqaM - - L - - - IstB-like ATP binding protein
LGCOMDED_01212 2.85e-97 yqaL - - L - - - DnaD domain protein
LGCOMDED_01213 1.79e-171 recT - - L ko:K07455 - ko00000,ko03400 RecT family
LGCOMDED_01214 1.33e-193 yqaJ - - L - - - YqaJ-like viral recombinase domain
LGCOMDED_01220 4.76e-105 - - - - - - - -
LGCOMDED_01221 4.03e-55 - - - S - - - DNA binding
LGCOMDED_01222 9.71e-48 - - - - - - - -
LGCOMDED_01223 5.23e-27 - - - K - - - Helix-turn-helix XRE-family like proteins
LGCOMDED_01224 6.27e-28 - - - K - - - transcriptional
LGCOMDED_01226 1.35e-61 xkdA - - E - - - IrrE N-terminal-like domain
LGCOMDED_01227 4.72e-183 - - - L - - - Belongs to the 'phage' integrase family
LGCOMDED_01228 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LGCOMDED_01229 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LGCOMDED_01230 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
LGCOMDED_01231 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
LGCOMDED_01232 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGCOMDED_01233 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LGCOMDED_01234 2.91e-146 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LGCOMDED_01235 5.96e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LGCOMDED_01236 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
LGCOMDED_01237 2.59e-238 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGCOMDED_01238 1.71e-109 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LGCOMDED_01239 6.87e-161 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
LGCOMDED_01240 7.42e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
LGCOMDED_01241 3.28e-232 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGCOMDED_01245 2.06e-125 - - - J - - - Acetyltransferase (GNAT) domain
LGCOMDED_01246 4.47e-123 yokK - - S - - - SMI1 / KNR4 family
LGCOMDED_01247 5.49e-102 - - - S - - - SMI1-KNR4 cell-wall
LGCOMDED_01248 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LGCOMDED_01249 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LGCOMDED_01250 3.55e-85 - - - G - - - SMI1-KNR4 cell-wall
LGCOMDED_01251 3.98e-49 - - - - - - - -
LGCOMDED_01252 1.94e-166 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
LGCOMDED_01253 2.3e-72 - - - S - - - DNase/tRNase domain of colicin-like bacteriocin
LGCOMDED_01254 3.42e-83 - - - S - - - SMI1 / KNR4 family
LGCOMDED_01256 8.77e-302 yokA - - L - - - Recombinase
LGCOMDED_01257 1.76e-124 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LGCOMDED_01258 2.04e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
LGCOMDED_01259 1.63e-131 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGCOMDED_01260 4.14e-94 ypoP - - K - - - transcriptional
LGCOMDED_01261 3.33e-288 mepA - - V - - - MATE efflux family protein
LGCOMDED_01262 1.24e-39 ypmT - - S - - - Uncharacterized ympT
LGCOMDED_01263 1.95e-128 ypmS - - S - - - protein conserved in bacteria
LGCOMDED_01264 1.49e-177 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
LGCOMDED_01265 5.15e-136 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LGCOMDED_01266 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
LGCOMDED_01267 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LGCOMDED_01268 1.34e-234 yplP - - K - - - Transcriptional regulator
LGCOMDED_01269 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
LGCOMDED_01270 1.15e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LGCOMDED_01271 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LGCOMDED_01272 2.43e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LGCOMDED_01273 5.16e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LGCOMDED_01274 4.51e-141 ypjP - - S - - - YpjP-like protein
LGCOMDED_01275 7.72e-181 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
LGCOMDED_01276 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
LGCOMDED_01277 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
LGCOMDED_01278 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
LGCOMDED_01279 6.48e-75 yagB - - S ko:K06950 - ko00000 phosphohydrolase
LGCOMDED_01280 3.66e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
LGCOMDED_01281 5e-224 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LGCOMDED_01282 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LGCOMDED_01283 5.12e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LGCOMDED_01284 1.17e-22 degR - - - - - - -
LGCOMDED_01285 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
LGCOMDED_01286 7.99e-41 ypeQ - - S - - - Zinc-finger
LGCOMDED_01287 1.9e-161 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
LGCOMDED_01288 1.14e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGCOMDED_01289 1.6e-89 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
LGCOMDED_01290 0.00015 - - - - ko:K06429 - ko00000 -
LGCOMDED_01291 2.26e-213 ypcP - - L - - - 5'3' exonuclease
LGCOMDED_01292 7.57e-12 - - - - - - - -
LGCOMDED_01293 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
LGCOMDED_01294 0.0 ypbR - - S - - - Dynamin family
LGCOMDED_01295 4.73e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
LGCOMDED_01296 1.07e-264 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
LGCOMDED_01297 2.47e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LGCOMDED_01298 2.34e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LGCOMDED_01299 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LGCOMDED_01300 5.8e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LGCOMDED_01301 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
LGCOMDED_01302 4.02e-237 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
LGCOMDED_01303 5.49e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
LGCOMDED_01304 1.2e-202 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LGCOMDED_01305 2.29e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_01306 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
LGCOMDED_01308 8.14e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
LGCOMDED_01309 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LGCOMDED_01310 3.99e-127 ypsA - - S - - - Belongs to the UPF0398 family
LGCOMDED_01311 4.87e-299 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
LGCOMDED_01312 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LGCOMDED_01313 1.34e-112 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
LGCOMDED_01314 1.24e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LGCOMDED_01315 8.72e-68 yppG - - S - - - YppG-like protein
LGCOMDED_01316 9.21e-11 - - - S - - - YppF-like protein
LGCOMDED_01317 7.14e-11 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
LGCOMDED_01320 4.54e-241 yppC - - S - - - Protein of unknown function (DUF2515)
LGCOMDED_01321 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LGCOMDED_01322 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LGCOMDED_01323 1.43e-121 ypoC - - - - - - -
LGCOMDED_01324 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGCOMDED_01325 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
LGCOMDED_01326 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
LGCOMDED_01327 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LGCOMDED_01328 2.27e-103 ypmB - - S - - - protein conserved in bacteria
LGCOMDED_01329 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
LGCOMDED_01330 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
LGCOMDED_01331 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGCOMDED_01332 1.83e-198 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGCOMDED_01333 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LGCOMDED_01334 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LGCOMDED_01335 6.13e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LGCOMDED_01336 2.01e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
LGCOMDED_01337 7.71e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
LGCOMDED_01338 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
LGCOMDED_01339 1.39e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LGCOMDED_01340 5.83e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
LGCOMDED_01341 2.14e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LGCOMDED_01342 6.84e-183 ypjB - - S - - - sporulation protein
LGCOMDED_01343 1.2e-127 ypjA - - S - - - membrane
LGCOMDED_01344 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
LGCOMDED_01345 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
LGCOMDED_01346 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
LGCOMDED_01347 1.86e-98 ypiF - - S - - - Protein of unknown function (DUF2487)
LGCOMDED_01348 1.83e-129 ypiB - - S - - - Belongs to the UPF0302 family
LGCOMDED_01349 5.27e-299 ypiA - - S - - - COG0457 FOG TPR repeat
LGCOMDED_01350 4.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LGCOMDED_01351 1.71e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
LGCOMDED_01352 1.5e-257 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGCOMDED_01353 7.71e-186 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LGCOMDED_01354 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LGCOMDED_01355 2.23e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
LGCOMDED_01356 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
LGCOMDED_01357 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGCOMDED_01358 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGCOMDED_01359 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LGCOMDED_01360 1.57e-260 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LGCOMDED_01361 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LGCOMDED_01362 2.13e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
LGCOMDED_01363 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LGCOMDED_01364 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LGCOMDED_01365 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LGCOMDED_01366 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LGCOMDED_01367 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LGCOMDED_01368 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
LGCOMDED_01369 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LGCOMDED_01370 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LGCOMDED_01371 1.5e-176 yphF - - - - - - -
LGCOMDED_01372 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
LGCOMDED_01373 8.18e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
LGCOMDED_01374 4.77e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
LGCOMDED_01375 1.02e-38 ypzH - - - - - - -
LGCOMDED_01376 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
LGCOMDED_01377 9.13e-133 yphA - - - - - - -
LGCOMDED_01378 1.13e-11 - - - S - - - YpzI-like protein
LGCOMDED_01379 1.33e-234 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LGCOMDED_01380 1.06e-259 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
LGCOMDED_01381 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
LGCOMDED_01382 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
LGCOMDED_01383 8.23e-138 ypfA - - M - - - Flagellar protein YcgR
LGCOMDED_01384 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
LGCOMDED_01385 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
LGCOMDED_01386 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
LGCOMDED_01387 8.76e-223 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
LGCOMDED_01388 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LGCOMDED_01389 3.22e-135 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LGCOMDED_01390 4.15e-186 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LGCOMDED_01391 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
LGCOMDED_01392 2.15e-125 ypbE - - M - - - Lysin motif
LGCOMDED_01393 4.14e-127 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
LGCOMDED_01394 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LGCOMDED_01395 4.66e-257 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
LGCOMDED_01396 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
LGCOMDED_01397 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LGCOMDED_01398 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGCOMDED_01399 7.94e-173 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LGCOMDED_01400 6.08e-254 rsiX - - - - - - -
LGCOMDED_01401 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_01402 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_01403 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_01404 1.1e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LGCOMDED_01405 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
LGCOMDED_01406 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LGCOMDED_01407 1.81e-168 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LGCOMDED_01408 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
LGCOMDED_01409 2.17e-134 spmA - - S ko:K06373 - ko00000 Spore maturation protein
LGCOMDED_01410 4.11e-273 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LGCOMDED_01411 6.13e-128 ypuI - - S - - - Protein of unknown function (DUF3907)
LGCOMDED_01412 2e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LGCOMDED_01413 4.45e-166 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LGCOMDED_01414 1.98e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
LGCOMDED_01415 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_01416 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LGCOMDED_01417 2.1e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGCOMDED_01418 1.24e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
LGCOMDED_01419 6.91e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGCOMDED_01420 5.98e-72 ypuD - - - - - - -
LGCOMDED_01421 1.54e-121 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LGCOMDED_01423 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
LGCOMDED_01424 2.51e-12 - - - S - - - SNARE associated Golgi protein
LGCOMDED_01426 5.94e-13 - - - M - - - Domain of Unknown Function (DUF1259)
LGCOMDED_01428 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGCOMDED_01429 2.67e-193 ypuA - - S - - - Secreted protein
LGCOMDED_01430 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LGCOMDED_01431 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
LGCOMDED_01432 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
LGCOMDED_01433 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
LGCOMDED_01434 2.86e-244 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LGCOMDED_01435 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LGCOMDED_01436 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
LGCOMDED_01437 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
LGCOMDED_01438 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_01439 3.93e-99 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LGCOMDED_01440 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
LGCOMDED_01441 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LGCOMDED_01442 5.66e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LGCOMDED_01443 2.77e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGCOMDED_01444 3.91e-214 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
LGCOMDED_01445 2.25e-49 - - - S - - - Protein of unknown function (DUF4227)
LGCOMDED_01446 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
LGCOMDED_01447 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LGCOMDED_01448 1.78e-42 yqkK - - - - - - -
LGCOMDED_01449 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LGCOMDED_01450 8.88e-317 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LGCOMDED_01451 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
LGCOMDED_01452 1.46e-237 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
LGCOMDED_01453 1.29e-76 ansR - - K - - - Transcriptional regulator
LGCOMDED_01454 4.16e-280 yqxK - - L - - - DNA helicase
LGCOMDED_01455 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
LGCOMDED_01456 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
LGCOMDED_01457 4.4e-216 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
LGCOMDED_01458 2.69e-25 yqkE - - S - - - Protein of unknown function (DUF3886)
LGCOMDED_01459 3.25e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LGCOMDED_01460 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
LGCOMDED_01461 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
LGCOMDED_01462 4.59e-248 yqkA - - K - - - GrpB protein
LGCOMDED_01463 2.63e-77 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
LGCOMDED_01464 2.22e-112 yqjY - - K ko:K06977 - ko00000 acetyltransferase
LGCOMDED_01465 1.87e-65 yqiX - - S - - - YolD-like protein
LGCOMDED_01466 2.43e-303 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGCOMDED_01468 6.83e-288 yqjV - - G - - - Major Facilitator Superfamily
LGCOMDED_01470 7.43e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LGCOMDED_01471 1.09e-227 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
LGCOMDED_01472 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
LGCOMDED_01473 9.78e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_01474 1.28e-226 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LGCOMDED_01475 9.98e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGCOMDED_01476 7.55e-59 orfX1 - - L - - - Transposase
LGCOMDED_01477 9.11e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
LGCOMDED_01478 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
LGCOMDED_01479 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
LGCOMDED_01480 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGCOMDED_01481 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGCOMDED_01482 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
LGCOMDED_01483 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGCOMDED_01484 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
LGCOMDED_01485 4.06e-134 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
LGCOMDED_01486 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
LGCOMDED_01487 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
LGCOMDED_01488 3.33e-114 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LGCOMDED_01489 3.69e-84 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LGCOMDED_01490 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGCOMDED_01491 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LGCOMDED_01493 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
LGCOMDED_01494 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
LGCOMDED_01495 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
LGCOMDED_01496 6.77e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LGCOMDED_01497 1.86e-116 mntP - - P - - - Probably functions as a manganese efflux pump
LGCOMDED_01498 1.11e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LGCOMDED_01499 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
LGCOMDED_01500 7.13e-123 ywlG - - S - - - Belongs to the UPF0340 family
LGCOMDED_01501 1.78e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LGCOMDED_01502 2.24e-147 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGCOMDED_01503 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
LGCOMDED_01504 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
LGCOMDED_01505 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LGCOMDED_01506 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGCOMDED_01507 1.95e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LGCOMDED_01508 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGCOMDED_01509 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGCOMDED_01510 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LGCOMDED_01511 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
LGCOMDED_01512 7.16e-114 ywmA - - - - - - -
LGCOMDED_01513 4.54e-45 ywzB - - S - - - membrane
LGCOMDED_01514 3.81e-171 ywmB - - S - - - TATA-box binding
LGCOMDED_01515 2.02e-305 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGCOMDED_01516 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
LGCOMDED_01517 1.28e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LGCOMDED_01518 5.87e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LGCOMDED_01520 3.69e-186 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LGCOMDED_01521 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGCOMDED_01522 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
LGCOMDED_01523 3.22e-109 ywmF - - S - - - Peptidase M50
LGCOMDED_01524 5.07e-18 csbD - - K - - - CsbD-like
LGCOMDED_01525 8.55e-281 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
LGCOMDED_01526 3.05e-188 - - - E ko:K11960 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LGCOMDED_01527 3.8e-233 - - - E ko:K01998,ko:K11961 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LGCOMDED_01528 9.77e-155 - - - S ko:K11962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
LGCOMDED_01529 1.1e-143 - - - E ko:K11963 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LGCOMDED_01530 8.2e-68 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
LGCOMDED_01531 1.78e-80 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
LGCOMDED_01532 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LGCOMDED_01533 4.58e-85 ywnA - - K - - - Transcriptional regulator
LGCOMDED_01534 3.27e-142 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
LGCOMDED_01535 1.24e-77 ywnC - - S - - - Family of unknown function (DUF5362)
LGCOMDED_01536 8.04e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
LGCOMDED_01537 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGCOMDED_01538 2.37e-90 ywnF - - S - - - Family of unknown function (DUF5392)
LGCOMDED_01539 3.99e-17 ywnC - - S - - - Family of unknown function (DUF5362)
LGCOMDED_01540 6.07e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
LGCOMDED_01541 1.07e-160 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LGCOMDED_01542 2.7e-94 ywnJ - - S - - - VanZ like family
LGCOMDED_01543 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
LGCOMDED_01544 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
LGCOMDED_01545 1.6e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
LGCOMDED_01546 9.77e-101 - - - - - - - -
LGCOMDED_01547 2.11e-133 yjgF - - Q - - - Isochorismatase family
LGCOMDED_01548 3.63e-305 ywoD - - EGP - - - Major facilitator superfamily
LGCOMDED_01549 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
LGCOMDED_01550 1.54e-307 ywoF - - P - - - Right handed beta helix region
LGCOMDED_01551 3.92e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LGCOMDED_01552 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
LGCOMDED_01553 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
LGCOMDED_01554 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
LGCOMDED_01555 6.18e-173 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LGCOMDED_01556 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
LGCOMDED_01557 4.47e-256 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
LGCOMDED_01558 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LGCOMDED_01559 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LGCOMDED_01560 9.97e-197 ywpD - - T - - - Histidine kinase
LGCOMDED_01561 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
LGCOMDED_01562 6.61e-184 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LGCOMDED_01563 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
LGCOMDED_01564 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
LGCOMDED_01565 1.22e-68 ytwF - - P - - - Sulfurtransferase
LGCOMDED_01566 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
LGCOMDED_01567 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
LGCOMDED_01568 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LGCOMDED_01569 3.14e-313 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
LGCOMDED_01570 2.08e-240 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_01571 3.38e-221 - - - S - - - Acetyl xylan esterase (AXE1)
LGCOMDED_01572 4.34e-177 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LGCOMDED_01573 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LGCOMDED_01574 5.21e-275 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LGCOMDED_01575 6.59e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGCOMDED_01576 1.86e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LGCOMDED_01577 1.91e-280 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LGCOMDED_01578 3.67e-177 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
LGCOMDED_01579 6.19e-193 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
LGCOMDED_01580 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LGCOMDED_01581 1.13e-165 ytdP - - K - - - Transcriptional regulator
LGCOMDED_01582 0.0 ytdP - - K - - - Transcriptional regulator
LGCOMDED_01583 2.27e-82 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LGCOMDED_01584 3.17e-122 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
LGCOMDED_01585 4.8e-278 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LGCOMDED_01586 2.27e-92 yteS - - G - - - transport
LGCOMDED_01587 1.06e-250 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
LGCOMDED_01588 8.22e-99 yteU - - S - - - Integral membrane protein
LGCOMDED_01589 2.14e-36 yteV - - S - - - Sporulation protein Cse60
LGCOMDED_01590 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
LGCOMDED_01591 1.16e-292 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
LGCOMDED_01592 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LGCOMDED_01593 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
LGCOMDED_01594 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
LGCOMDED_01595 5.66e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LGCOMDED_01596 4.28e-256 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
LGCOMDED_01597 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
LGCOMDED_01598 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
LGCOMDED_01599 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LGCOMDED_01600 1.5e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGCOMDED_01601 9.92e-212 ytlQ - - - - - - -
LGCOMDED_01602 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
LGCOMDED_01603 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
LGCOMDED_01604 3.02e-192 ytmP - - M - - - Phosphotransferase
LGCOMDED_01605 9.51e-61 ytzH - - S - - - YtzH-like protein
LGCOMDED_01606 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LGCOMDED_01607 1.06e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LGCOMDED_01608 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LGCOMDED_01609 1.17e-67 ytzB - - S - - - small secreted protein
LGCOMDED_01610 3.56e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
LGCOMDED_01611 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LGCOMDED_01612 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
LGCOMDED_01613 3.17e-75 ytpP - - CO - - - Thioredoxin
LGCOMDED_01614 1.1e-190 ytpQ - - S - - - Belongs to the UPF0354 family
LGCOMDED_01615 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LGCOMDED_01616 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
LGCOMDED_01617 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
LGCOMDED_01618 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LGCOMDED_01619 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
LGCOMDED_01620 2.23e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
LGCOMDED_01621 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LGCOMDED_01622 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
LGCOMDED_01623 6.84e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LGCOMDED_01624 1.31e-160 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LGCOMDED_01625 2.65e-292 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
LGCOMDED_01626 1.77e-151 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
LGCOMDED_01627 2.43e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LGCOMDED_01628 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LGCOMDED_01629 2.16e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LGCOMDED_01630 5e-48 - - - - - - - -
LGCOMDED_01631 2.51e-180 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
LGCOMDED_01632 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_01633 5.31e-291 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_01634 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_01635 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_01636 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
LGCOMDED_01637 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LGCOMDED_01638 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LGCOMDED_01639 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
LGCOMDED_01640 8.4e-203 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
LGCOMDED_01641 5.06e-81 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
LGCOMDED_01642 3.71e-235 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LGCOMDED_01643 1.73e-252 yubA - - S - - - transporter activity
LGCOMDED_01644 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LGCOMDED_01646 1.3e-72 - - - L - - - Arm DNA-binding domain
LGCOMDED_01647 2.69e-23 - - - K - - - Helix-turn-helix XRE-family like proteins
LGCOMDED_01651 1.43e-185 - - - S - - - N-methyltransferase activity
LGCOMDED_01656 3.36e-277 - - - - - - - -
LGCOMDED_01660 3.03e-46 - - - - - - - -
LGCOMDED_01661 4.94e-56 - - - - - - - -
LGCOMDED_01662 6.05e-80 - - - - - - - -
LGCOMDED_01663 8.65e-38 - - - - - - - -
LGCOMDED_01667 1.53e-106 - - - L - - - Integrase
LGCOMDED_01668 7.74e-252 - - - S - - - TIGRFAM Phage
LGCOMDED_01669 3.32e-143 - - - S - - - Phage portal protein, SPP1 Gp6-like
LGCOMDED_01670 1.94e-26 - - - S - - - Domain of unknown function (DUF4355)
LGCOMDED_01671 5.91e-118 - - - S - - - P22 coat protein - gene protein 5
LGCOMDED_01675 0.0 - - - S - - - peptidoglycan catabolic process
LGCOMDED_01681 9.02e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LGCOMDED_01682 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LGCOMDED_01683 4.36e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
LGCOMDED_01685 1.94e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
LGCOMDED_01690 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
LGCOMDED_01691 0.0 yubD - - P - - - Major Facilitator Superfamily
LGCOMDED_01692 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LGCOMDED_01693 3.31e-52 yubF - - S - - - yiaA/B two helix domain
LGCOMDED_01694 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
LGCOMDED_01695 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LGCOMDED_01696 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
LGCOMDED_01697 2.82e-140 yttP - - K - - - Transcriptional regulator
LGCOMDED_01698 1.03e-195 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LGCOMDED_01699 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LGCOMDED_01700 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LGCOMDED_01701 4.75e-267 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LGCOMDED_01702 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGCOMDED_01703 7.14e-39 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LGCOMDED_01704 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LGCOMDED_01705 0.0 ytcJ - - S - - - amidohydrolase
LGCOMDED_01706 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGCOMDED_01707 3.96e-229 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
LGCOMDED_01708 8.23e-112 yteJ - - S - - - RDD family
LGCOMDED_01709 6.29e-144 ytfI - - S - - - Protein of unknown function (DUF2953)
LGCOMDED_01710 5.02e-90 ytfJ - - S - - - Sporulation protein YtfJ
LGCOMDED_01711 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGCOMDED_01712 2.44e-220 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
LGCOMDED_01713 1.52e-280 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGCOMDED_01714 9.5e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
LGCOMDED_01715 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
LGCOMDED_01716 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
LGCOMDED_01718 1.98e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_01719 5.47e-166 ytkL - - S - - - Belongs to the UPF0173 family
LGCOMDED_01720 4.99e-223 ytlI - - K ko:K21960 - ko00000,ko03000 LysR substrate binding domain
LGCOMDED_01721 4e-128 ytmI - - K ko:K00680 - ko00000,ko01000 Acetyltransferase (GNAT) domain
LGCOMDED_01722 9.11e-195 - - - ET ko:K16956,ko:K16957,ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LGCOMDED_01723 1.87e-188 tcyK - - M ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
LGCOMDED_01724 1.66e-157 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LGCOMDED_01725 1.77e-149 - - - U ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
LGCOMDED_01726 6.61e-183 tcyN - - E ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LGCOMDED_01727 8.4e-235 ytmO - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGCOMDED_01728 5.26e-63 ytnI - - O - - - COG0695 Glutaredoxin and related proteins
LGCOMDED_01729 0.0 ytnJ - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGCOMDED_01730 1.98e-165 - 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin kinase
LGCOMDED_01731 5.44e-235 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
LGCOMDED_01732 8.36e-202 ytnM - - S ko:K07090 - ko00000 membrane transporter protein
LGCOMDED_01733 3.25e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
LGCOMDED_01734 2.15e-63 ytpI - - S - - - YtpI-like protein
LGCOMDED_01735 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
LGCOMDED_01736 1.15e-39 - - - - - - - -
LGCOMDED_01737 5.12e-112 ytrI - - - - - - -
LGCOMDED_01738 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
LGCOMDED_01739 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
LGCOMDED_01740 8.53e-287 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
LGCOMDED_01741 1.25e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LGCOMDED_01742 4e-233 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LGCOMDED_01743 1.89e-228 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LGCOMDED_01744 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
LGCOMDED_01745 3.85e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
LGCOMDED_01746 7.83e-245 ytvI - - S - - - sporulation integral membrane protein YtvI
LGCOMDED_01747 9.38e-95 ytwI - - S - - - membrane
LGCOMDED_01748 1.17e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LGCOMDED_01749 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
LGCOMDED_01750 1.04e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
LGCOMDED_01751 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_01752 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
LGCOMDED_01753 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGCOMDED_01754 7.84e-200 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LGCOMDED_01755 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
LGCOMDED_01756 8.07e-126 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LGCOMDED_01757 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
LGCOMDED_01758 1.42e-75 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
LGCOMDED_01759 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LGCOMDED_01760 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
LGCOMDED_01761 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LGCOMDED_01762 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LGCOMDED_01763 2.11e-251 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
LGCOMDED_01764 6.09e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LGCOMDED_01765 2.59e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LGCOMDED_01766 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LGCOMDED_01767 1.91e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
LGCOMDED_01768 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
LGCOMDED_01769 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LGCOMDED_01770 3.52e-173 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGCOMDED_01771 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
LGCOMDED_01772 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
LGCOMDED_01773 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LGCOMDED_01774 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
LGCOMDED_01775 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGCOMDED_01776 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LGCOMDED_01777 4.03e-104 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGCOMDED_01778 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LGCOMDED_01779 5.1e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
LGCOMDED_01780 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGCOMDED_01781 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGCOMDED_01782 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
LGCOMDED_01783 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGCOMDED_01784 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LGCOMDED_01785 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LGCOMDED_01786 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGCOMDED_01787 8.42e-236 ybaC - - S - - - Alpha/beta hydrolase family
LGCOMDED_01788 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
LGCOMDED_01789 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGCOMDED_01790 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
LGCOMDED_01791 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LGCOMDED_01792 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGCOMDED_01793 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGCOMDED_01794 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGCOMDED_01795 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LGCOMDED_01796 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGCOMDED_01797 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
LGCOMDED_01798 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGCOMDED_01799 7.32e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGCOMDED_01800 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LGCOMDED_01801 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGCOMDED_01802 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LGCOMDED_01803 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LGCOMDED_01804 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LGCOMDED_01805 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LGCOMDED_01806 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGCOMDED_01807 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
LGCOMDED_01808 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
LGCOMDED_01809 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LGCOMDED_01810 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LGCOMDED_01811 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
LGCOMDED_01812 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGCOMDED_01813 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
LGCOMDED_01814 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGCOMDED_01815 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LGCOMDED_01816 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGCOMDED_01817 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
LGCOMDED_01818 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LGCOMDED_01819 1.1e-194 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LGCOMDED_01820 4.39e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LGCOMDED_01821 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LGCOMDED_01822 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGCOMDED_01823 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
LGCOMDED_01824 7.18e-185 ybaJ - - Q - - - Methyltransferase domain
LGCOMDED_01825 1.96e-15 ybaK - - S - - - Protein of unknown function (DUF2521)
LGCOMDED_01826 3.1e-36 ybaK - - S - - - Protein of unknown function (DUF2521)
LGCOMDED_01827 3.03e-168 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LGCOMDED_01828 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LGCOMDED_01829 1.04e-122 gerD - - - ko:K06294 - ko00000 -
LGCOMDED_01830 1.1e-132 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
LGCOMDED_01831 1.75e-180 pdaB - - G - - - Polysaccharide deacetylase
LGCOMDED_01832 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGCOMDED_01833 4.27e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LGCOMDED_01834 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LGCOMDED_01835 3.65e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
LGCOMDED_01836 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_01837 2.81e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
LGCOMDED_01838 2.01e-141 ykoF - - S - - - YKOF-related Family
LGCOMDED_01839 4.3e-159 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_01840 1.42e-305 ykoH - - T - - - Histidine kinase
LGCOMDED_01841 3.74e-143 ykoI - - S - - - Peptidase propeptide and YPEB domain
LGCOMDED_01842 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
LGCOMDED_01843 1.45e-08 - - - - - - - -
LGCOMDED_01845 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
LGCOMDED_01846 1.49e-70 tnrA - - K - - - transcriptional
LGCOMDED_01847 1.63e-25 - - - - - - - -
LGCOMDED_01848 3.04e-36 ykoL - - - - - - -
LGCOMDED_01849 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
LGCOMDED_01850 1.76e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LGCOMDED_01851 2.07e-126 ykoP - - G - - - polysaccharide deacetylase
LGCOMDED_01852 7.22e-197 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
LGCOMDED_01853 0.0 ykoS - - - - - - -
LGCOMDED_01854 2.23e-236 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LGCOMDED_01855 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
LGCOMDED_01856 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LGCOMDED_01857 1.41e-69 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LGCOMDED_01858 1.89e-31 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LGCOMDED_01859 7.7e-29 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LGCOMDED_01860 3.09e-66 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LGCOMDED_01861 2.46e-74 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LGCOMDED_01862 2.43e-76 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
LGCOMDED_01863 1.71e-143 ykoX - - S - - - membrane-associated protein
LGCOMDED_01864 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LGCOMDED_01865 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_01866 1.41e-199 rsgI - - S - - - Anti-sigma factor N-terminus
LGCOMDED_01867 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
LGCOMDED_01868 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
LGCOMDED_01869 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
LGCOMDED_01870 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
LGCOMDED_01872 1.77e-28 ykzE - - - - - - -
LGCOMDED_01873 3.2e-242 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
LGCOMDED_01874 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_01875 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGCOMDED_01877 5.4e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LGCOMDED_01878 5.81e-292 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LGCOMDED_01879 8.12e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LGCOMDED_01880 6.56e-294 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LGCOMDED_01881 3.25e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LGCOMDED_01882 6.91e-173 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LGCOMDED_01883 2.15e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LGCOMDED_01884 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LGCOMDED_01885 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
LGCOMDED_01887 1.88e-91 eag - - - - - - -
LGCOMDED_01888 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LGCOMDED_01889 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
LGCOMDED_01890 1.06e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
LGCOMDED_01891 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
LGCOMDED_01892 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
LGCOMDED_01893 3.91e-226 ykvI - - S - - - membrane
LGCOMDED_01894 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGCOMDED_01895 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
LGCOMDED_01896 5.91e-178 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LGCOMDED_01897 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LGCOMDED_01898 3.22e-278 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LGCOMDED_01899 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
LGCOMDED_01900 9.45e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
LGCOMDED_01901 3.1e-288 - - - EGP - - - Major Facilitator Superfamily
LGCOMDED_01902 4.76e-119 - - - S - - - YcxB-like protein
LGCOMDED_01903 1.09e-203 ycxC - - EG - - - EamA-like transporter family
LGCOMDED_01904 9.36e-317 ycxD - - K - - - GntR family transcriptional regulator
LGCOMDED_01905 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
LGCOMDED_01906 8.71e-148 yczE - - S ko:K07149 - ko00000 membrane
LGCOMDED_01907 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LGCOMDED_01908 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LGCOMDED_01909 4.13e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
LGCOMDED_01910 2.08e-206 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
LGCOMDED_01911 9.12e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LGCOMDED_01912 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LGCOMDED_01913 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
LGCOMDED_01914 6.45e-55 yclD - - - - - - -
LGCOMDED_01915 1.11e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
LGCOMDED_01916 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
LGCOMDED_01917 0.0 yclG - - M - - - Pectate lyase superfamily protein
LGCOMDED_01919 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
LGCOMDED_01920 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
LGCOMDED_01921 8.19e-248 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
LGCOMDED_01922 4.82e-155 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
LGCOMDED_01923 1.45e-275 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
LGCOMDED_01924 2.23e-165 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_01925 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LGCOMDED_01926 3.09e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LGCOMDED_01928 6.5e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LGCOMDED_01929 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LGCOMDED_01930 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_01931 4.69e-211 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_01932 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_01933 1.91e-211 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
LGCOMDED_01934 0.0 ycnB - - EGP - - - the major facilitator superfamily
LGCOMDED_01935 5.87e-198 ycnC - - K - - - Transcriptional regulator
LGCOMDED_01936 2.48e-173 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LGCOMDED_01937 1.68e-60 ycnE - - S - - - Monooxygenase
LGCOMDED_01938 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LGCOMDED_01939 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_01940 6.58e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LGCOMDED_01941 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LGCOMDED_01942 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
LGCOMDED_01943 1.39e-185 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_01944 1.34e-132 ycnI - - S - - - protein conserved in bacteria
LGCOMDED_01945 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
LGCOMDED_01946 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LGCOMDED_01947 4.67e-75 - - - - - - - -
LGCOMDED_01948 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
LGCOMDED_01949 3.38e-94 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LGCOMDED_01950 1.72e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
LGCOMDED_01951 5.86e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
LGCOMDED_01953 4.01e-93 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LGCOMDED_01954 6.98e-143 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
LGCOMDED_01955 1.89e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
LGCOMDED_01956 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_01957 9.81e-47 nucB - - M - - - Deoxyribonuclease NucA/NucB
LGCOMDED_01958 1.49e-167 - - - - - - - -
LGCOMDED_01959 1.54e-216 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
LGCOMDED_01960 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
LGCOMDED_01961 1.33e-173 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
LGCOMDED_01962 6.41e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
LGCOMDED_01964 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
LGCOMDED_01965 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LGCOMDED_01966 3.3e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGCOMDED_01967 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
LGCOMDED_01968 5.83e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGCOMDED_01969 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
LGCOMDED_01970 6.61e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LGCOMDED_01971 9.8e-179 yqeM - - Q - - - Methyltransferase
LGCOMDED_01972 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGCOMDED_01973 6.65e-138 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
LGCOMDED_01974 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
LGCOMDED_01975 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
LGCOMDED_01976 2.36e-22 - - - S - - - YqzM-like protein
LGCOMDED_01977 2.74e-242 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
LGCOMDED_01978 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
LGCOMDED_01979 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGCOMDED_01980 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
LGCOMDED_01981 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
LGCOMDED_01982 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LGCOMDED_01983 1.96e-274 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
LGCOMDED_01984 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LGCOMDED_01985 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGCOMDED_01986 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
LGCOMDED_01987 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LGCOMDED_01988 5.63e-226 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
LGCOMDED_01989 1.38e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LGCOMDED_01990 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
LGCOMDED_01991 1.09e-199 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
LGCOMDED_01992 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
LGCOMDED_01993 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
LGCOMDED_01994 7.62e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
LGCOMDED_01995 4.35e-192 yqfA - - S - - - UPF0365 protein
LGCOMDED_01996 3.13e-79 yqfB - - - - - - -
LGCOMDED_01997 2.07e-60 yqfC - - S - - - sporulation protein YqfC
LGCOMDED_01998 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
LGCOMDED_01999 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
LGCOMDED_02001 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
LGCOMDED_02002 2.49e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGCOMDED_02003 2.26e-78 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
LGCOMDED_02004 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LGCOMDED_02005 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGCOMDED_02006 5.29e-27 - - - S - - - YqzL-like protein
LGCOMDED_02007 1.24e-185 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
LGCOMDED_02008 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
LGCOMDED_02009 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
LGCOMDED_02010 3.29e-144 ccpN - - K - - - CBS domain
LGCOMDED_02011 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LGCOMDED_02012 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
LGCOMDED_02013 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LGCOMDED_02014 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LGCOMDED_02015 2.29e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LGCOMDED_02016 5.67e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
LGCOMDED_02017 2.44e-265 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGCOMDED_02018 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LGCOMDED_02019 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LGCOMDED_02020 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LGCOMDED_02021 1.94e-245 - - - S - - - Glycosyl hydrolase
LGCOMDED_02022 5.81e-306 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_02023 1.13e-197 yvbV - - EG - - - EamA-like transporter family
LGCOMDED_02024 6.96e-206 yvbU - - K - - - Transcriptional regulator
LGCOMDED_02025 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGCOMDED_02026 6.14e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
LGCOMDED_02027 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LGCOMDED_02028 9.43e-235 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LGCOMDED_02029 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LGCOMDED_02030 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
LGCOMDED_02031 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LGCOMDED_02032 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
LGCOMDED_02033 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LGCOMDED_02034 6.83e-97 yvbK - - K - - - acetyltransferase
LGCOMDED_02035 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
LGCOMDED_02036 3.11e-154 yvbI - - M - - - Membrane
LGCOMDED_02037 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
LGCOMDED_02038 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
LGCOMDED_02039 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LGCOMDED_02040 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LGCOMDED_02041 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LGCOMDED_02042 5e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LGCOMDED_02043 1.03e-146 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LGCOMDED_02044 9.63e-60 sdpR - - K - - - transcriptional
LGCOMDED_02045 8.32e-133 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LGCOMDED_02047 1.13e-222 - - - - - - - -
LGCOMDED_02048 2.75e-11 - - - S - - - Sporulation delaying protein SdpA
LGCOMDED_02049 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
LGCOMDED_02050 9.58e-267 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LGCOMDED_02051 2.57e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LGCOMDED_02052 2.37e-220 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LGCOMDED_02053 1.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
LGCOMDED_02054 5.82e-258 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_02055 3.65e-24 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_02056 3.85e-72 yvaP - - K - - - transcriptional
LGCOMDED_02057 1.98e-91 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
LGCOMDED_02058 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
LGCOMDED_02059 4.9e-48 yvzC - - K - - - transcriptional
LGCOMDED_02060 3.87e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
LGCOMDED_02061 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
LGCOMDED_02062 2.42e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
LGCOMDED_02063 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LGCOMDED_02064 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGCOMDED_02066 7.66e-180 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_02067 5.77e-127 - - - K - - - Bacterial regulatory proteins, tetR family
LGCOMDED_02068 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
LGCOMDED_02069 8.22e-97 yvaD - - S - - - Family of unknown function (DUF5360)
LGCOMDED_02070 0.0 - - - S - - - Fusaric acid resistance protein-like
LGCOMDED_02071 2.08e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGCOMDED_02072 1.4e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
LGCOMDED_02073 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
LGCOMDED_02074 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
LGCOMDED_02075 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
LGCOMDED_02076 1.11e-54 ybyB - - - - - - -
LGCOMDED_02077 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
LGCOMDED_02078 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
LGCOMDED_02079 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
LGCOMDED_02080 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
LGCOMDED_02081 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_02082 6.05e-272 ybdO - - S - - - Domain of unknown function (DUF4885)
LGCOMDED_02083 3.67e-193 ybdN - - - - - - -
LGCOMDED_02084 1.68e-179 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
LGCOMDED_02086 4.22e-214 - - - T - - - His Kinase A (phospho-acceptor) domain
LGCOMDED_02087 6.9e-158 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
LGCOMDED_02088 1.82e-229 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LGCOMDED_02089 5.88e-103 - - - CO - - - Thioredoxin-like domain
LGCOMDED_02090 3.88e-118 - - - C - - - HEAT repeats
LGCOMDED_02091 1e-310 skfF - - S - - - ABC transporter
LGCOMDED_02092 1.9e-170 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
LGCOMDED_02093 0.0 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
LGCOMDED_02094 7.24e-304 - - - J - - - 4Fe-4S single cluster domain
LGCOMDED_02096 9.37e-258 ybcL - - EGP ko:K08164 - ko00000,ko02000 COG2814 Arabinose efflux permease
LGCOMDED_02097 9.45e-67 - - - K - - - Helix-turn-helix domain
LGCOMDED_02098 2.96e-79 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
LGCOMDED_02099 1.6e-63 - - - - - - - -
LGCOMDED_02101 3.85e-120 ybcF - - P - - - carbonic anhydrase
LGCOMDED_02102 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
LGCOMDED_02103 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LGCOMDED_02104 2.6e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGCOMDED_02105 1.53e-48 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LGCOMDED_02106 1.15e-46 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
LGCOMDED_02107 4.24e-217 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LGCOMDED_02108 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LGCOMDED_02109 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGCOMDED_02110 1.61e-289 ybbR - - S - - - protein conserved in bacteria
LGCOMDED_02111 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LGCOMDED_02112 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LGCOMDED_02113 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_02119 4.03e-99 ybbK - - S - - - Protein of unknown function (DUF523)
LGCOMDED_02120 2.62e-79 ybbJ - - J - - - acetyltransferase
LGCOMDED_02121 9.51e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LGCOMDED_02122 3.51e-190 ybbH - - K - - - transcriptional
LGCOMDED_02123 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_02124 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
LGCOMDED_02125 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
LGCOMDED_02126 1.84e-299 ybbC - - S - - - protein conserved in bacteria
LGCOMDED_02127 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
LGCOMDED_02128 5.97e-215 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
LGCOMDED_02129 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_02130 4.99e-228 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_02131 6.65e-183 ybbA - - S ko:K07017 - ko00000 Putative esterase
LGCOMDED_02132 2.34e-203 ybaS - - S - - - Na -dependent transporter
LGCOMDED_02133 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LGCOMDED_02134 1.56e-08 - - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LGCOMDED_02135 6.29e-10 - - - S - - - DegQ (SacQ) family
LGCOMDED_02136 8.73e-09 yuzC - - - - - - -
LGCOMDED_02137 2.92e-298 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
LGCOMDED_02138 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGCOMDED_02139 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
LGCOMDED_02140 5.37e-88 - - - S - - - Protein of unknown function (DUF1694)
LGCOMDED_02141 1.34e-51 yueH - - S - - - YueH-like protein
LGCOMDED_02142 1.19e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
LGCOMDED_02143 3.71e-242 yueF - - S - - - transporter activity
LGCOMDED_02144 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
LGCOMDED_02145 4.86e-32 - - - S - - - Protein of unknown function (DUF2642)
LGCOMDED_02146 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
LGCOMDED_02147 1.96e-167 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_02148 4.37e-97 yueC - - S - - - Family of unknown function (DUF5383)
LGCOMDED_02149 0.0 yueB - - S - - - type VII secretion protein EsaA
LGCOMDED_02150 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LGCOMDED_02151 5.18e-270 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
LGCOMDED_02152 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
LGCOMDED_02153 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
LGCOMDED_02154 4.03e-290 yukF - - QT - - - Transcriptional regulator
LGCOMDED_02155 5.47e-260 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
LGCOMDED_02156 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
LGCOMDED_02157 1.66e-46 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
LGCOMDED_02158 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LGCOMDED_02159 3.15e-228 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
LGCOMDED_02160 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
LGCOMDED_02161 3.34e-287 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LGCOMDED_02162 1.95e-176 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_02163 8.94e-213 eSD - - S ko:K07017 - ko00000 Putative esterase
LGCOMDED_02164 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
LGCOMDED_02165 1.38e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
LGCOMDED_02166 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
LGCOMDED_02167 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGCOMDED_02168 7.09e-101 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
LGCOMDED_02169 6.61e-149 yuiC - - S - - - protein conserved in bacteria
LGCOMDED_02170 1.97e-46 yuiB - - S - - - Putative membrane protein
LGCOMDED_02171 6.9e-300 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LGCOMDED_02172 5.51e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
LGCOMDED_02174 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LGCOMDED_02175 6.43e-146 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
LGCOMDED_02176 1.64e-86 paiA 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_02177 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
LGCOMDED_02178 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGCOMDED_02179 2.97e-268 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGCOMDED_02180 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
LGCOMDED_02181 9.17e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
LGCOMDED_02182 5.44e-74 yuzD - - S - - - protein conserved in bacteria
LGCOMDED_02183 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
LGCOMDED_02184 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
LGCOMDED_02185 2.99e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LGCOMDED_02186 5.64e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LGCOMDED_02187 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
LGCOMDED_02188 8.97e-253 yutH - - S - - - Spore coat protein
LGCOMDED_02189 3.34e-112 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
LGCOMDED_02190 3.03e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LGCOMDED_02191 2.38e-99 yutE - - S - - - Protein of unknown function DUF86
LGCOMDED_02192 2.17e-61 yutD - - S - - - protein conserved in bacteria
LGCOMDED_02193 2.71e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LGCOMDED_02194 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGCOMDED_02195 7.63e-252 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
LGCOMDED_02196 2.54e-168 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
LGCOMDED_02197 1.33e-59 yunC - - S - - - Domain of unknown function (DUF1805)
LGCOMDED_02198 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LGCOMDED_02199 2.65e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
LGCOMDED_02200 1.73e-219 yunF - - S - - - Protein of unknown function DUF72
LGCOMDED_02201 1.85e-61 yunG - - - - - - -
LGCOMDED_02202 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LGCOMDED_02203 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
LGCOMDED_02204 1.99e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
LGCOMDED_02205 1.76e-280 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
LGCOMDED_02206 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LGCOMDED_02207 1.21e-71 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LGCOMDED_02208 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LGCOMDED_02209 1.99e-121 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LGCOMDED_02210 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LGCOMDED_02211 4.27e-188 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LGCOMDED_02212 3.58e-142 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
LGCOMDED_02213 3.18e-237 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LGCOMDED_02214 3.32e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LGCOMDED_02215 1.68e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LGCOMDED_02216 2.1e-214 bsn - - L - - - Ribonuclease
LGCOMDED_02217 1.91e-30 - - - S - - - branched-chain amino acid
LGCOMDED_02218 1.3e-93 - - - E - - - AzlC protein
LGCOMDED_02219 8.01e-198 gntR9 - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_02220 2.47e-47 - - - L - - - COG3666 Transposase and inactivated derivatives
LGCOMDED_02221 1.15e-84 - - - L - - - COG3666 Transposase and inactivated derivatives
LGCOMDED_02223 1.52e-215 megL 4.4.1.11 - E ko:K01761 ko00270,ko00450,map00270,map00450 ko00000,ko00001,ko01000 methionine gamma-lyase
LGCOMDED_02224 1.3e-27 - - - I - - - Fatty acid desaturase
LGCOMDED_02225 4.23e-100 - - - I - - - Fatty acid desaturase
LGCOMDED_02226 0.000162 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
LGCOMDED_02227 3.78e-250 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_02228 2.5e-174 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LGCOMDED_02229 1.05e-187 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
LGCOMDED_02230 1.65e-194 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LGCOMDED_02231 2.72e-79 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
LGCOMDED_02232 1.51e-234 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LGCOMDED_02233 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
LGCOMDED_02234 7.86e-266 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
LGCOMDED_02236 3.35e-56 - - - - - - - -
LGCOMDED_02237 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
LGCOMDED_02238 3.26e-72 - - - L - - - transposase activity
LGCOMDED_02239 5.06e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LGCOMDED_02240 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LGCOMDED_02241 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
LGCOMDED_02242 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
LGCOMDED_02243 1.63e-298 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGCOMDED_02244 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
LGCOMDED_02245 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LGCOMDED_02246 3.06e-60 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LGCOMDED_02247 7.98e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
LGCOMDED_02248 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
LGCOMDED_02249 2.5e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LGCOMDED_02250 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
LGCOMDED_02251 8.14e-73 yusE - - CO - - - Thioredoxin
LGCOMDED_02252 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
LGCOMDED_02253 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
LGCOMDED_02254 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LGCOMDED_02255 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
LGCOMDED_02256 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
LGCOMDED_02257 7.74e-278 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
LGCOMDED_02258 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
LGCOMDED_02259 1.11e-13 - - - S - - - YuzL-like protein
LGCOMDED_02260 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LGCOMDED_02261 2.23e-54 - - - - - - - -
LGCOMDED_02262 2.29e-69 yusN - - M - - - Coat F domain
LGCOMDED_02263 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
LGCOMDED_02264 0.0 yusP - - P - - - Major facilitator superfamily
LGCOMDED_02265 2.82e-83 yusQ - - S - - - Tautomerase enzyme
LGCOMDED_02266 2.87e-137 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_02267 1.98e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LGCOMDED_02268 1.05e-63 yusU - - S - - - Protein of unknown function (DUF2573)
LGCOMDED_02269 1.06e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LGCOMDED_02270 4.94e-88 - - - S - - - YusW-like protein
LGCOMDED_02271 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
LGCOMDED_02272 3.16e-196 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_02273 2.15e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
LGCOMDED_02274 3.08e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGCOMDED_02275 2.23e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_02276 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_02277 5.07e-203 yuxN - - K - - - Transcriptional regulator
LGCOMDED_02278 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LGCOMDED_02279 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
LGCOMDED_02280 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LGCOMDED_02281 1.13e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LGCOMDED_02282 8.74e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
LGCOMDED_02283 1.1e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_02284 2.35e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_02285 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
LGCOMDED_02286 6.68e-171 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
LGCOMDED_02287 2.44e-143 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LGCOMDED_02288 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
LGCOMDED_02289 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LGCOMDED_02290 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
LGCOMDED_02291 7.72e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LGCOMDED_02292 1.56e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_02293 2.98e-218 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LGCOMDED_02294 1.18e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_02295 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
LGCOMDED_02296 0.0 yvrG - - T - - - Histidine kinase
LGCOMDED_02297 3.16e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_02298 5.07e-32 - - - - - - - -
LGCOMDED_02299 4.55e-124 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
LGCOMDED_02300 6.98e-26 - - - S - - - YvrJ protein family
LGCOMDED_02301 2.17e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LGCOMDED_02302 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
LGCOMDED_02303 8.98e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LGCOMDED_02304 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_02305 8.47e-230 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
LGCOMDED_02306 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LGCOMDED_02307 6.5e-224 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_02308 2.72e-233 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGCOMDED_02309 4.45e-225 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LGCOMDED_02310 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
LGCOMDED_02311 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
LGCOMDED_02312 6.83e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
LGCOMDED_02313 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
LGCOMDED_02314 4.91e-212 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
LGCOMDED_02315 8.94e-177 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
LGCOMDED_02316 7.09e-153 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
LGCOMDED_02317 2.52e-200 yvgN - - S - - - reductase
LGCOMDED_02318 7.97e-113 yvgO - - - - - - -
LGCOMDED_02319 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
LGCOMDED_02320 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LGCOMDED_02321 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGCOMDED_02322 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LGCOMDED_02323 3.88e-140 yvgT - - S - - - membrane
LGCOMDED_02324 1.64e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
LGCOMDED_02325 1.71e-137 bdbD - - O - - - Thioredoxin
LGCOMDED_02326 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LGCOMDED_02327 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
LGCOMDED_02328 1.82e-130 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LGCOMDED_02329 2.92e-259 yaaN - - P - - - Belongs to the TelA family
LGCOMDED_02330 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
LGCOMDED_02331 5.46e-145 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGCOMDED_02332 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
LGCOMDED_02333 1.48e-94 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
LGCOMDED_02334 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
LGCOMDED_02335 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
LGCOMDED_02336 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
LGCOMDED_02337 2.81e-178 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
LGCOMDED_02338 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
LGCOMDED_02339 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGCOMDED_02340 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
LGCOMDED_02341 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGCOMDED_02342 1.39e-182 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
LGCOMDED_02343 1.86e-274 yabE - - T - - - protein conserved in bacteria
LGCOMDED_02344 4.09e-125 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LGCOMDED_02345 1.05e-195 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LGCOMDED_02346 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
LGCOMDED_02347 5.32e-53 veg - - S - - - protein conserved in bacteria
LGCOMDED_02348 1.28e-35 sspF - - S ko:K06423 - ko00000 DNA topological change
LGCOMDED_02349 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LGCOMDED_02350 1.56e-194 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
LGCOMDED_02351 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
LGCOMDED_02352 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LGCOMDED_02353 2.58e-309 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LGCOMDED_02354 1.22e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGCOMDED_02355 1.69e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LGCOMDED_02356 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LGCOMDED_02357 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
LGCOMDED_02358 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGCOMDED_02359 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
LGCOMDED_02360 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LGCOMDED_02361 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LGCOMDED_02362 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LGCOMDED_02363 1.91e-66 yabP - - S - - - Sporulation protein YabP
LGCOMDED_02364 5.21e-138 yabQ - - S - - - spore cortex biosynthesis protein
LGCOMDED_02365 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
LGCOMDED_02366 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LGCOMDED_02369 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
LGCOMDED_02370 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
LGCOMDED_02371 6.92e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
LGCOMDED_02372 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LGCOMDED_02373 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
LGCOMDED_02374 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGCOMDED_02375 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LGCOMDED_02376 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LGCOMDED_02377 2.23e-194 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
LGCOMDED_02378 8.88e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
LGCOMDED_02379 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGCOMDED_02380 1.72e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
LGCOMDED_02381 1.26e-213 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
LGCOMDED_02382 9.13e-203 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGCOMDED_02383 3.12e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGCOMDED_02384 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGCOMDED_02385 1.81e-41 yazB - - K - - - transcriptional
LGCOMDED_02386 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGCOMDED_02387 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
LGCOMDED_02390 1.01e-100 - - - L - - - Phage integrase, N-terminal SAM-like domain
LGCOMDED_02391 2.54e-31 xkdA - - E - - - IrrE N-terminal-like domain
LGCOMDED_02393 1.41e-23 - - - K - - - Helix-turn-helix domain
LGCOMDED_02395 2.87e-15 - - - S - - - Helix-turn-helix domain
LGCOMDED_02396 2.32e-57 - - - - - - - -
LGCOMDED_02400 1.08e-227 - - - D - - - nuclear chromosome segregation
LGCOMDED_02402 2.49e-109 bet - - L - - - RecT family
LGCOMDED_02403 1.77e-131 - - - S - - - Metallo-beta-lactamase superfamily
LGCOMDED_02405 2.89e-34 - - - L - - - primosome component and related proteins
LGCOMDED_02407 5.3e-227 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
LGCOMDED_02410 2.86e-75 rusA - - L - - - Endodeoxyribonuclease RusA
LGCOMDED_02411 1.19e-88 - - - - - - - -
LGCOMDED_02414 7.84e-34 - - - - - - - -
LGCOMDED_02419 3.74e-77 - - - - - - - -
LGCOMDED_02420 1.73e-50 - - - - - - - -
LGCOMDED_02422 3.56e-05 - - - - - - - -
LGCOMDED_02425 5.12e-82 - - - K - - - DNA binding
LGCOMDED_02426 9.76e-125 - - - - - - - -
LGCOMDED_02427 5.5e-42 - - - - - - - -
LGCOMDED_02429 5.46e-109 - - - - - - - -
LGCOMDED_02430 4.04e-296 yqaT - - S ko:K06909 - ko00000 phage terminase, large subunit
LGCOMDED_02431 0.0 yqbA - - S - - - portal protein
LGCOMDED_02432 4.77e-183 - - - S - - - Phage Mu protein F like protein
LGCOMDED_02434 1.15e-155 yqbD - - L - - - Putative phage serine protease XkdF
LGCOMDED_02435 2.12e-189 xkdG - - S - - - Phage capsid family
LGCOMDED_02436 1.53e-33 - - - S - - - YqbF, hypothetical protein domain
LGCOMDED_02437 3.97e-62 - - - S - - - Protein of unknown function (DUF3199)
LGCOMDED_02438 9.69e-74 yqbH - - S - - - Domain of unknown function (DUF3599)
LGCOMDED_02439 3.08e-113 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LGCOMDED_02440 2.98e-89 yqbJ - - - - - - -
LGCOMDED_02441 4.78e-30 - - - - - - - -
LGCOMDED_02442 1.02e-311 xkdK - - S - - - Phage tail sheath C-terminal domain
LGCOMDED_02443 6.75e-96 xkdM - - S - - - Phage tail tube protein
LGCOMDED_02444 1.42e-86 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
LGCOMDED_02445 1.89e-22 - - - - - - - -
LGCOMDED_02446 0.0 xkdO - - L - - - Transglycosylase SLT domain
LGCOMDED_02447 6.37e-152 xkdP - - S - - - Lysin motif
LGCOMDED_02448 7.68e-227 xkdQ - - G - - - NLP P60 protein
LGCOMDED_02449 3.46e-43 xkdR - - S - - - Protein of unknown function (DUF2577)
LGCOMDED_02450 3.52e-86 xkdS - - S - - - Protein of unknown function (DUF2634)
LGCOMDED_02451 4.31e-235 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LGCOMDED_02452 1.3e-124 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
LGCOMDED_02453 1.33e-48 - - - - - - - -
LGCOMDED_02454 6.55e-210 - - - - - - - -
LGCOMDED_02455 2.99e-57 xkdW - - S - - - XkdW protein
LGCOMDED_02456 8.43e-27 - - - - - - - -
LGCOMDED_02457 6.51e-193 xepA - - - - - - -
LGCOMDED_02458 3.43e-36 xhlA - - S - - - Haemolysin XhlA
LGCOMDED_02459 8.15e-44 xhlB - - S - - - SPP1 phage holin
LGCOMDED_02460 2.41e-159 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LGCOMDED_02463 9.31e-37 - - - - - - - -
LGCOMDED_02464 8.99e-227 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LGCOMDED_02465 2.7e-202 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
LGCOMDED_02467 6.74e-50 - - - S - - - YolD-like protein
LGCOMDED_02468 1e-13 - - - - - - - -
LGCOMDED_02469 1.91e-13 - 3.4.21.88 - KT ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 PFAM LexA DNA-binding domain protein
LGCOMDED_02471 8.04e-96 - - - J - - - Acetyltransferase (GNAT) domain
LGCOMDED_02479 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
LGCOMDED_02480 1.08e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
LGCOMDED_02481 1.8e-177 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGCOMDED_02482 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LGCOMDED_02483 1.9e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
LGCOMDED_02484 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
LGCOMDED_02485 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LGCOMDED_02486 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
LGCOMDED_02487 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
LGCOMDED_02488 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
LGCOMDED_02489 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LGCOMDED_02490 7.21e-282 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGCOMDED_02491 2.21e-232 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
LGCOMDED_02492 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LGCOMDED_02493 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
LGCOMDED_02494 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
LGCOMDED_02495 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
LGCOMDED_02496 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LGCOMDED_02497 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LGCOMDED_02498 1.03e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
LGCOMDED_02499 4.19e-75 ydbP - - CO - - - Thioredoxin
LGCOMDED_02500 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGCOMDED_02502 1.49e-26 - - - S - - - Fur-regulated basic protein B
LGCOMDED_02503 5.03e-278 ydbM - - I - - - acyl-CoA dehydrogenase
LGCOMDED_02504 3.8e-69 ydbL - - - - - - -
LGCOMDED_02505 8.57e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LGCOMDED_02506 5.36e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_02507 1.32e-230 ydbI - - S - - - AI-2E family transporter
LGCOMDED_02508 5.16e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LGCOMDED_02509 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LGCOMDED_02510 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LGCOMDED_02511 1.23e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LGCOMDED_02512 2.74e-176 ydbD - - P ko:K07217 - ko00000 Catalase
LGCOMDED_02513 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
LGCOMDED_02514 3.09e-78 ydbB - - G - - - Cupin domain
LGCOMDED_02515 1.83e-09 gsiB - - S ko:K06884 - ko00000 general stress protein
LGCOMDED_02516 9.36e-154 ydbA - - P - - - EcsC protein family
LGCOMDED_02517 1.39e-89 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
LGCOMDED_02518 1.67e-42 ydaS - - S - - - membrane
LGCOMDED_02519 3.9e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
LGCOMDED_02520 3.04e-53 - - - - - - - -
LGCOMDED_02522 1.14e-265 ydaM - - M - - - Glycosyl transferase family group 2
LGCOMDED_02523 0.0 ydaL - - S - - - Uncharacterized protein conserved in bacteria (DUF2334)
LGCOMDED_02524 7.07e-115 ydaK - - T - - - Diguanylate cyclase, GGDEF domain
LGCOMDED_02525 2.43e-264 ydaJ - - M - - - Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGCOMDED_02526 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGCOMDED_02527 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LGCOMDED_02528 1.05e-59 ydzA - - EGP - - - Domain of unknown function (DUF3817)
LGCOMDED_02529 1.31e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LGCOMDED_02530 5.24e-101 ydaG - - S - - - general stress protein
LGCOMDED_02531 1.28e-131 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LGCOMDED_02532 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
LGCOMDED_02533 2.09e-201 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_02534 6.78e-126 ydaC - - Q - - - Methyltransferase domain
LGCOMDED_02535 1.21e-87 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
LGCOMDED_02537 8.18e-289 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
LGCOMDED_02538 8.31e-226 ytcB - - M - - - NAD-dependent epimerase dehydratase
LGCOMDED_02539 1.67e-309 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LGCOMDED_02540 2.32e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
LGCOMDED_02541 5.02e-168 yteA - - T - - - COG1734 DnaK suppressor protein
LGCOMDED_02542 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
LGCOMDED_02543 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGCOMDED_02544 4.49e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LGCOMDED_02545 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGCOMDED_02546 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LGCOMDED_02547 7.07e-273 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LGCOMDED_02548 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LGCOMDED_02549 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LGCOMDED_02550 8.31e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LGCOMDED_02551 3.22e-192 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LGCOMDED_02552 9.9e-34 - - - S - - - Domain of Unknown Function (DUF1540)
LGCOMDED_02553 3.3e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LGCOMDED_02554 6.19e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
LGCOMDED_02555 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
LGCOMDED_02556 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LGCOMDED_02557 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LGCOMDED_02558 4.78e-95 ytkA - - S - - - YtkA-like
LGCOMDED_02560 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
LGCOMDED_02561 1.52e-79 ytkC - - S - - - Bacteriophage holin family
LGCOMDED_02562 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
LGCOMDED_02563 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LGCOMDED_02564 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
LGCOMDED_02565 1.08e-239 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LGCOMDED_02566 1.06e-187 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LGCOMDED_02567 1.16e-51 ytmB - - S - - - Protein of unknown function (DUF2584)
LGCOMDED_02568 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGCOMDED_02569 3.07e-284 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGCOMDED_02570 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LGCOMDED_02571 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_02572 2.39e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGCOMDED_02573 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
LGCOMDED_02574 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
LGCOMDED_02575 3.91e-136 ytqB - - J - - - Putative rRNA methylase
LGCOMDED_02576 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
LGCOMDED_02577 3.64e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
LGCOMDED_02579 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
LGCOMDED_02580 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_02581 3.78e-10 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LGCOMDED_02582 6.95e-159 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LGCOMDED_02583 3.57e-188 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
LGCOMDED_02584 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_02585 8.41e-298 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LGCOMDED_02586 9.83e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_02587 8.4e-235 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
LGCOMDED_02588 7.41e-177 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_02589 5.81e-46 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LGCOMDED_02590 5.45e-114 - - - - - - - -
LGCOMDED_02591 2.41e-07 - - - S - - - nucleic acid binding
LGCOMDED_02592 0.0 - - - S - - - RNA-directed RNA polymerase activity
LGCOMDED_02595 3.44e-302 - - - - - - - -
LGCOMDED_02596 4.68e-06 - - - L - - - SNF2 family N-terminal domain
LGCOMDED_02597 3.75e-248 - - - L - - - Domain of unknown function (DUF4942)
LGCOMDED_02607 2.95e-114 - - - - - - - -
LGCOMDED_02612 1.1e-65 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
LGCOMDED_02615 1.23e-43 yoaF - - - - - - -
LGCOMDED_02617 1.6e-134 - - - - - - - -
LGCOMDED_02622 9.71e-253 - - - L - - - Belongs to the 'phage' integrase family
LGCOMDED_02623 0.0 - - - S - - - DNA-sulfur modification-associated
LGCOMDED_02624 2.89e-226 - - - - - - - -
LGCOMDED_02625 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_02630 1.78e-68 - - - S - - - dUTPase
LGCOMDED_02631 4.95e-19 - - - T - - - AAA domain
LGCOMDED_02635 1.37e-116 - - - S - - - Protein of unknown function (DUF1273)
LGCOMDED_02642 1.75e-188 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
LGCOMDED_02644 8.64e-197 - - - - - - - -
LGCOMDED_02653 1.94e-179 - - - L - - - Participates in initiation and elongation during chromosome replication
LGCOMDED_02654 3.93e-65 - - - S - - - DNA primase activity
LGCOMDED_02655 6.95e-145 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LGCOMDED_02656 3.15e-182 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LGCOMDED_02657 1.1e-138 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
LGCOMDED_02658 2.05e-178 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
LGCOMDED_02659 5.02e-158 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
LGCOMDED_02660 2.81e-82 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LGCOMDED_02661 1.35e-74 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
LGCOMDED_02662 6.09e-65 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LGCOMDED_02663 1.12e-207 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
LGCOMDED_02664 2.26e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
LGCOMDED_02665 2.94e-195 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LGCOMDED_02666 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
LGCOMDED_02667 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_02668 1.28e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
LGCOMDED_02669 1.41e-119 yisT - - S - - - DinB family
LGCOMDED_02670 7.35e-249 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LGCOMDED_02671 4.83e-231 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
LGCOMDED_02672 1.65e-206 yisR - - K - - - Transcriptional regulator
LGCOMDED_02673 2.91e-310 yisQ - - V - - - Mate efflux family protein
LGCOMDED_02674 8.1e-151 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
LGCOMDED_02675 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
LGCOMDED_02676 3.68e-132 yisN - - S - - - Protein of unknown function (DUF2777)
LGCOMDED_02677 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LGCOMDED_02678 5.88e-74 yisL - - S - - - UPF0344 protein
LGCOMDED_02679 2.19e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LGCOMDED_02680 1.04e-219 cotH - - M ko:K06330 - ko00000 Spore Coat
LGCOMDED_02681 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
LGCOMDED_02682 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
LGCOMDED_02683 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
LGCOMDED_02684 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
LGCOMDED_02685 7.36e-34 gerPD - - S ko:K06302 - ko00000 Spore germination protein
LGCOMDED_02686 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
LGCOMDED_02687 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
LGCOMDED_02688 2.41e-62 yisB - - V - - - COG1403 Restriction endonuclease
LGCOMDED_02689 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
LGCOMDED_02690 4.67e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LGCOMDED_02691 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
LGCOMDED_02692 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
LGCOMDED_02693 9.3e-102 yhjR - - S - - - Rubrerythrin
LGCOMDED_02694 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
LGCOMDED_02695 7.04e-270 - - - EGP - - - Transmembrane secretion effector
LGCOMDED_02696 2.5e-259 yhjN - - S ko:K07120 - ko00000 membrane
LGCOMDED_02697 1.77e-238 yhjM - - K - - - Transcriptional regulator
LGCOMDED_02698 3.75e-146 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LGCOMDED_02699 6.26e-100 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LGCOMDED_02700 1.07e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
LGCOMDED_02701 1.89e-255 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
LGCOMDED_02702 4.73e-306 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LGCOMDED_02703 2.29e-29 ywtC - - - - - - -
LGCOMDED_02704 3.66e-275 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LGCOMDED_02705 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
LGCOMDED_02706 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
LGCOMDED_02707 9.35e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
LGCOMDED_02708 1.07e-205 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGCOMDED_02709 4.61e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LGCOMDED_02710 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LGCOMDED_02711 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LGCOMDED_02712 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
LGCOMDED_02713 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
LGCOMDED_02714 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
LGCOMDED_02715 1.45e-124 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
LGCOMDED_02716 6.15e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
LGCOMDED_02717 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
LGCOMDED_02718 3.36e-218 alsR - - K - - - LysR substrate binding domain
LGCOMDED_02719 1.79e-227 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGCOMDED_02720 1.06e-162 ywrJ - - - - - - -
LGCOMDED_02721 4.21e-112 cotB - - - ko:K06325 - ko00000 -
LGCOMDED_02722 3.12e-29 cotB - - - ko:K06325 - ko00000 -
LGCOMDED_02723 1.2e-264 cotH - - M ko:K06330 - ko00000 Spore Coat
LGCOMDED_02724 5.01e-18 - - - - - - - -
LGCOMDED_02725 3.43e-140 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGCOMDED_02726 3.8e-69 - - - S - - - Domain of unknown function (DUF4181)
LGCOMDED_02727 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
LGCOMDED_02728 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
LGCOMDED_02729 4.53e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
LGCOMDED_02730 2.47e-113 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
LGCOMDED_02732 5.23e-130 ywqN - - S - - - NAD(P)H-dependent
LGCOMDED_02733 4.73e-209 - - - K - - - Transcriptional regulator
LGCOMDED_02734 1.77e-149 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LGCOMDED_02736 3.64e-98 ywqJ - - S - - - Pre-toxin TG
LGCOMDED_02737 1.3e-23 - - - - - - - -
LGCOMDED_02738 1.77e-26 - - - - - - - -
LGCOMDED_02739 1.27e-264 - - - L - - - nucleic acid phosphodiester bond hydrolysis
LGCOMDED_02740 2.47e-50 ywqI - - S - - - Family of unknown function (DUF5344)
LGCOMDED_02742 3.44e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
LGCOMDED_02743 5.43e-312 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LGCOMDED_02744 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
LGCOMDED_02745 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LGCOMDED_02746 2.17e-162 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
LGCOMDED_02747 3.6e-25 - - - - - - - -
LGCOMDED_02748 0.0 ywqB - - S - - - SWIM zinc finger
LGCOMDED_02749 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LGCOMDED_02750 1.45e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LGCOMDED_02751 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
LGCOMDED_02752 1.04e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
LGCOMDED_02753 3.56e-86 ywpG - - - - - - -
LGCOMDED_02754 3.59e-88 ywpF - - S - - - YwpF-like protein
LGCOMDED_02755 5.72e-199 yknT - - - ko:K06437 - ko00000 -
LGCOMDED_02756 1.86e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LGCOMDED_02757 8.86e-244 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LGCOMDED_02758 1.23e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
LGCOMDED_02759 1.64e-120 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
LGCOMDED_02760 3.83e-109 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
LGCOMDED_02761 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGCOMDED_02762 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LGCOMDED_02763 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LGCOMDED_02764 1.6e-151 yknW - - S - - - Yip1 domain
LGCOMDED_02765 2.72e-232 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGCOMDED_02766 1.23e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_02767 3.88e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
LGCOMDED_02768 7.41e-176 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_02769 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
LGCOMDED_02770 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LGCOMDED_02771 1.42e-133 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LGCOMDED_02772 7.71e-52 ykoA - - - - - - -
LGCOMDED_02773 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LGCOMDED_02774 3.9e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGCOMDED_02775 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
LGCOMDED_02776 1.09e-18 - - - S - - - Uncharacterized protein YkpC
LGCOMDED_02777 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
LGCOMDED_02778 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
LGCOMDED_02779 3.77e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
LGCOMDED_02780 1.15e-196 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
LGCOMDED_02781 1.01e-147 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
LGCOMDED_02782 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LGCOMDED_02783 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LGCOMDED_02784 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
LGCOMDED_02785 5.59e-185 ykrA - - S - - - hydrolases of the HAD superfamily
LGCOMDED_02786 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LGCOMDED_02787 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
LGCOMDED_02788 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
LGCOMDED_02789 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LGCOMDED_02790 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LGCOMDED_02791 9.88e-300 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LGCOMDED_02792 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LGCOMDED_02793 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
LGCOMDED_02794 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
LGCOMDED_02795 1.34e-56 yktA - - S - - - Belongs to the UPF0223 family
LGCOMDED_02796 5.28e-152 yktB - - S - - - Belongs to the UPF0637 family
LGCOMDED_02797 4.48e-35 ykzI - - - - - - -
LGCOMDED_02798 3.18e-193 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
LGCOMDED_02799 6.82e-78 ykzC - - S - - - Acetyltransferase (GNAT) family
LGCOMDED_02800 1.67e-219 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LGCOMDED_02802 3.65e-13 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
LGCOMDED_02806 1.67e-75 - - - L - - - COG3666 Transposase and inactivated derivatives
LGCOMDED_02807 5.22e-199 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGCOMDED_02808 1.35e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
LGCOMDED_02809 1.84e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LGCOMDED_02810 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
LGCOMDED_02811 4.42e-73 ydfQ - - CO - - - Thioredoxin
LGCOMDED_02812 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
LGCOMDED_02813 5.33e-39 - - - - - - - -
LGCOMDED_02815 4.33e-34 ydfR - - S - - - Protein of unknown function (DUF421)
LGCOMDED_02816 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
LGCOMDED_02817 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
LGCOMDED_02818 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LGCOMDED_02819 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
LGCOMDED_02820 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
LGCOMDED_02821 8.51e-128 ydgC - - K - - - Bacterial regulatory proteins, tetR family
LGCOMDED_02822 3.2e-67 - - - S - - - DoxX-like family
LGCOMDED_02823 1.97e-111 yycN - - K - - - Acetyltransferase
LGCOMDED_02824 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
LGCOMDED_02825 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_02826 3.44e-117 - - - S - - - DinB family
LGCOMDED_02827 2.06e-104 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_02828 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
LGCOMDED_02829 6.42e-147 ydgI - - C - - - nitroreductase
LGCOMDED_02830 1.9e-89 - - - K - - - Winged helix DNA-binding domain
LGCOMDED_02831 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
LGCOMDED_02832 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
LGCOMDED_02833 5.24e-158 ydhC - - K - - - FCD
LGCOMDED_02834 8.92e-310 ydhD - - M - - - Glycosyl hydrolase
LGCOMDED_02835 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LGCOMDED_02836 3.52e-162 - - - - - - - -
LGCOMDED_02837 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LGCOMDED_02838 5.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
LGCOMDED_02840 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
LGCOMDED_02841 5.45e-233 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
LGCOMDED_02842 1.15e-127 ydhK - - M - - - Protein of unknown function (DUF1541)
LGCOMDED_02843 6.3e-255 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
LGCOMDED_02844 1.88e-63 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_02845 4.82e-67 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_02846 3.23e-305 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LGCOMDED_02847 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LGCOMDED_02848 3.16e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
LGCOMDED_02849 2.74e-211 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
LGCOMDED_02850 5.09e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LGCOMDED_02851 1.66e-271 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LGCOMDED_02852 8.68e-150 ydhU - - P ko:K07217 - ko00000 Catalase
LGCOMDED_02853 1.59e-21 ydhU - - P ko:K07217 - ko00000 Manganese containing catalase
LGCOMDED_02856 1.92e-140 yodC - - C - - - nitroreductase
LGCOMDED_02857 2.63e-73 yodB - - K - - - transcriptional
LGCOMDED_02858 1.14e-83 iolK - - S - - - tautomerase
LGCOMDED_02859 3.09e-288 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LGCOMDED_02860 3.94e-14 - - - - - - - -
LGCOMDED_02861 3.51e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
LGCOMDED_02862 5.49e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
LGCOMDED_02863 1.85e-58 - - - - - - - -
LGCOMDED_02864 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
LGCOMDED_02865 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
LGCOMDED_02866 8.33e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LGCOMDED_02867 1.89e-309 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
LGCOMDED_02869 6.12e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LGCOMDED_02870 1.09e-291 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
LGCOMDED_02871 1.05e-263 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LGCOMDED_02872 4.94e-140 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGCOMDED_02873 5.42e-207 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
LGCOMDED_02874 0.0 yojO - - P - - - Von Willebrand factor
LGCOMDED_02875 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LGCOMDED_02876 2.59e-264 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LGCOMDED_02877 4.7e-214 yocS - - S ko:K03453 - ko00000 -transporter
LGCOMDED_02878 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LGCOMDED_02879 4.57e-210 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
LGCOMDED_02880 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
LGCOMDED_02881 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LGCOMDED_02882 1.91e-42 yozC - - - - - - -
LGCOMDED_02883 2.17e-74 yozO - - S - - - Bacterial PH domain
LGCOMDED_02884 1.83e-49 yocN - - - - - - -
LGCOMDED_02885 2.94e-55 yozN - - - - - - -
LGCOMDED_02886 1.5e-111 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
LGCOMDED_02887 6.54e-40 - - - - - - - -
LGCOMDED_02888 4.29e-70 yocL - - - - - - -
LGCOMDED_02889 1.42e-107 yocK - - T - - - general stress protein
LGCOMDED_02890 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGCOMDED_02891 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
LGCOMDED_02892 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
LGCOMDED_02893 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_02894 9.63e-250 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_02895 5.67e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LGCOMDED_02896 3.06e-237 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
LGCOMDED_02897 2.99e-119 yocC - - - - - - -
LGCOMDED_02898 2.39e-181 - - - - - - - -
LGCOMDED_02899 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
LGCOMDED_02900 1.89e-179 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
LGCOMDED_02901 5.63e-251 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGCOMDED_02902 1.53e-35 - - - - - - - -
LGCOMDED_02903 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LGCOMDED_02904 5.8e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
LGCOMDED_02905 2.58e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LGCOMDED_02906 9.61e-208 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
LGCOMDED_02907 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
LGCOMDED_02908 3.36e-87 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LGCOMDED_02909 4.42e-285 - - - S - - - Recombinase
LGCOMDED_02910 2.85e-93 - - - S - - - Pfam:Peptidase_M78
LGCOMDED_02911 1.41e-82 - - - S - - - sequence-specific DNA binding
LGCOMDED_02912 1.62e-12 - - - K - - - helix-turn-helix
LGCOMDED_02915 5e-64 - - - - - - - -
LGCOMDED_02916 1.17e-13 - - - - - - - -
LGCOMDED_02917 6.05e-206 - - - L - - - Protein of unknown function (DUF2800)
LGCOMDED_02918 1.11e-114 - - - S - - - Protein of unknown function (DUF2815)
LGCOMDED_02920 1.07e-05 - - - - - - - -
LGCOMDED_02921 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
LGCOMDED_02923 0.0 - - - L - - - Virulence-associated protein E
LGCOMDED_02924 2.22e-32 - - - S - - - VRR_NUC
LGCOMDED_02925 3.74e-288 - - - KL - - - SNF2 family N-terminal domain
LGCOMDED_02926 2.58e-65 - - - - - - - -
LGCOMDED_02927 3.5e-64 - - - - - - - -
LGCOMDED_02929 2.11e-101 - - - L - - - phage terminase small subunit
LGCOMDED_02930 0.0 - - - S - - - Terminase
LGCOMDED_02931 1.17e-221 - - - S - - - Phage portal protein
LGCOMDED_02932 9.23e-103 - - - S - - - peptidase activity
LGCOMDED_02933 3.19e-203 - - - S - - - capsid protein
LGCOMDED_02934 2.99e-34 - - - - - - - -
LGCOMDED_02935 1.2e-53 - - - S - - - Phage gp6-like head-tail connector protein
LGCOMDED_02936 4.3e-51 - - - S - - - Phage head-tail joining protein
LGCOMDED_02937 3.42e-66 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
LGCOMDED_02939 1.67e-101 - - - N - - - Phage major tail protein phi13
LGCOMDED_02942 0.0 - - - D - - - phage tail tape measure protein
LGCOMDED_02943 5.91e-143 - - - S - - - Phage tail protein
LGCOMDED_02944 4.08e-277 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
LGCOMDED_02945 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
LGCOMDED_02946 4.89e-146 - - - S - - - Domain of unknown function (DUF2479)
LGCOMDED_02949 4.44e-38 bhlA - - S - - - BhlA holin family
LGCOMDED_02950 3.19e-41 xhlB - - S - - - SPP1 phage holin
LGCOMDED_02951 1.11e-166 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LGCOMDED_02952 2.79e-08 - - - S - - - Immunity protein 50
LGCOMDED_02953 6.29e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
LGCOMDED_02954 1.32e-137 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
LGCOMDED_02960 4.75e-38 - - - K - - - Helix-turn-helix domain
LGCOMDED_02963 5.34e-66 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
LGCOMDED_02964 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
LGCOMDED_02965 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
LGCOMDED_02966 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
LGCOMDED_02967 2.05e-156 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LGCOMDED_02968 6.84e-185 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
LGCOMDED_02969 3.69e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
LGCOMDED_02970 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
LGCOMDED_02971 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
LGCOMDED_02972 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
LGCOMDED_02973 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
LGCOMDED_02974 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
LGCOMDED_02975 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGCOMDED_02976 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
LGCOMDED_02977 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
LGCOMDED_02978 5.86e-122 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
LGCOMDED_02979 1.12e-288 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LGCOMDED_02980 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
LGCOMDED_02981 9.81e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
LGCOMDED_02982 3.78e-271 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGCOMDED_02983 5.73e-209 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
LGCOMDED_02984 6.81e-67 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LGCOMDED_02985 8.27e-163 yebC - - K - - - transcriptional regulatory protein
LGCOMDED_02986 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
LGCOMDED_02987 3.62e-67 - - - S - - - Family of unknown function (DUF5412)
LGCOMDED_02989 2.32e-152 yrzF - - T - - - serine threonine protein kinase
LGCOMDED_02990 2.77e-248 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
LGCOMDED_02991 0.0 csbX - - EGP - - - the major facilitator superfamily
LGCOMDED_02992 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
LGCOMDED_02993 1.64e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LGCOMDED_02994 3.72e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LGCOMDED_02995 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
LGCOMDED_02996 2.46e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LGCOMDED_02997 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LGCOMDED_02998 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
LGCOMDED_02999 2.95e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
LGCOMDED_03000 1.67e-142 yrbG - - S - - - membrane
LGCOMDED_03001 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LGCOMDED_03002 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
LGCOMDED_03003 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGCOMDED_03004 6.51e-114 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LGCOMDED_03005 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
LGCOMDED_03006 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
LGCOMDED_03007 1.46e-117 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGCOMDED_03008 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGCOMDED_03009 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LGCOMDED_03010 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
LGCOMDED_03012 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
LGCOMDED_03013 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGCOMDED_03014 3.96e-177 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LGCOMDED_03015 2e-302 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LGCOMDED_03016 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03017 1.87e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
LGCOMDED_03018 1.19e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LGCOMDED_03019 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
LGCOMDED_03020 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LGCOMDED_03021 2.79e-105 yrrD - - S - - - protein conserved in bacteria
LGCOMDED_03022 8.4e-42 yrzR - - - - - - -
LGCOMDED_03023 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
LGCOMDED_03024 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LGCOMDED_03025 9.28e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
LGCOMDED_03026 1.05e-186 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LGCOMDED_03027 9.37e-170 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LGCOMDED_03028 2.42e-239 yrrI - - S - - - AI-2E family transporter
LGCOMDED_03029 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGCOMDED_03030 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
LGCOMDED_03031 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGCOMDED_03032 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
LGCOMDED_03033 7.51e-242 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGCOMDED_03034 1.4e-154 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
LGCOMDED_03035 6.57e-224 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
LGCOMDED_03036 3.8e-312 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
LGCOMDED_03037 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
LGCOMDED_03038 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LGCOMDED_03039 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
LGCOMDED_03040 1.42e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
LGCOMDED_03041 8.52e-37 yrzA - - S - - - Protein of unknown function (DUF2536)
LGCOMDED_03042 7.23e-155 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
LGCOMDED_03043 1.97e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGCOMDED_03044 7.04e-218 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
LGCOMDED_03045 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LGCOMDED_03046 6.93e-49 yrhC - - S - - - YrhC-like protein
LGCOMDED_03047 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
LGCOMDED_03048 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
LGCOMDED_03049 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
LGCOMDED_03051 1.96e-183 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
LGCOMDED_03053 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
LGCOMDED_03054 5.86e-122 yrhH - - Q - - - methyltransferase
LGCOMDED_03055 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
LGCOMDED_03056 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LGCOMDED_03057 4.27e-59 yrhK - - S - - - YrhK-like protein
LGCOMDED_03058 0.0 oatA - - I - - - Acyltransferase family
LGCOMDED_03059 7.09e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
LGCOMDED_03060 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_03061 5.9e-194 yrhO - - K - - - Archaeal transcriptional regulator TrmB
LGCOMDED_03062 1.88e-135 yrhP - - E - - - LysE type translocator
LGCOMDED_03063 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_03064 0.0 levR - - K - - - PTS system fructose IIA component
LGCOMDED_03065 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
LGCOMDED_03066 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
LGCOMDED_03067 2.79e-166 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LGCOMDED_03068 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LGCOMDED_03069 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LGCOMDED_03070 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
LGCOMDED_03071 6.28e-249 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
LGCOMDED_03072 2.32e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
LGCOMDED_03073 3.79e-31 yraD - - M ko:K06439 - ko00000 Spore coat protein
LGCOMDED_03074 9.21e-197 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_03075 9.86e-201 yitH - - K - - - Acetyltransferase (GNAT) domain
LGCOMDED_03076 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
LGCOMDED_03077 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LGCOMDED_03078 1.5e-77 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
LGCOMDED_03079 1.31e-202 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
LGCOMDED_03080 4.16e-122 - - - - - - - -
LGCOMDED_03081 1.48e-74 - - - - - - - -
LGCOMDED_03082 1.26e-110 - - - - - - - -
LGCOMDED_03083 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
LGCOMDED_03084 2.08e-77 - - - K - - - Transcriptional regulator PadR-like family
LGCOMDED_03085 9.34e-119 - - - - - - - -
LGCOMDED_03086 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
LGCOMDED_03087 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
LGCOMDED_03088 1.07e-200 yitS - - S - - - protein conserved in bacteria
LGCOMDED_03089 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LGCOMDED_03090 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
LGCOMDED_03091 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
LGCOMDED_03092 1.92e-08 - - - - - - - -
LGCOMDED_03093 4.35e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LGCOMDED_03094 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
LGCOMDED_03095 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
LGCOMDED_03096 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
LGCOMDED_03097 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
LGCOMDED_03098 1.32e-113 yitZ - - G - - - Major Facilitator Superfamily
LGCOMDED_03099 8.29e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LGCOMDED_03100 7.1e-293 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LGCOMDED_03101 2.56e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
LGCOMDED_03102 6.59e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
LGCOMDED_03103 8.11e-263 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
LGCOMDED_03104 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
LGCOMDED_03105 1.43e-223 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LGCOMDED_03106 2.51e-39 yjzC - - S - - - YjzC-like protein
LGCOMDED_03107 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
LGCOMDED_03108 8.09e-181 yjaU - - I - - - carboxylic ester hydrolase activity
LGCOMDED_03109 1.43e-129 yjaV - - - - - - -
LGCOMDED_03110 7.48e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
LGCOMDED_03111 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
LGCOMDED_03112 2.67e-38 yjzB - - - - - - -
LGCOMDED_03113 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGCOMDED_03114 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LGCOMDED_03115 4.51e-191 yjaZ - - O - - - Zn-dependent protease
LGCOMDED_03116 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_03117 1.99e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_03118 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
LGCOMDED_03119 1.58e-214 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGCOMDED_03120 1.22e-196 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGCOMDED_03121 1.84e-189 yjbA - - S - - - Belongs to the UPF0736 family
LGCOMDED_03122 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LGCOMDED_03123 1.03e-299 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LGCOMDED_03124 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
LGCOMDED_03125 2.16e-48 - - - - - - - -
LGCOMDED_03126 1.01e-68 mstX - - S - - - Membrane-integrating protein Mistic
LGCOMDED_03127 2.06e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
LGCOMDED_03128 1.42e-93 yugN - - S - - - YugN-like family
LGCOMDED_03130 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
LGCOMDED_03131 3.22e-290 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
LGCOMDED_03132 6.7e-286 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
LGCOMDED_03133 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
LGCOMDED_03134 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
LGCOMDED_03135 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
LGCOMDED_03136 6.74e-112 alaR - - K - - - Transcriptional regulator
LGCOMDED_03137 9.89e-201 yugF - - I - - - Hydrolase
LGCOMDED_03138 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
LGCOMDED_03139 1.16e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LGCOMDED_03140 6.13e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03141 4.84e-89 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
LGCOMDED_03142 1.41e-148 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
LGCOMDED_03144 3.79e-243 yuxJ - - EGP - - - Major facilitator superfamily
LGCOMDED_03145 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
LGCOMDED_03146 1.92e-97 yuxK - - S - - - protein conserved in bacteria
LGCOMDED_03147 1.2e-112 yufK - - S - - - Family of unknown function (DUF5366)
LGCOMDED_03148 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
LGCOMDED_03149 3.26e-162 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
LGCOMDED_03150 5e-253 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
LGCOMDED_03151 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_03152 2.6e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LGCOMDED_03153 4.9e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
LGCOMDED_03154 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
LGCOMDED_03155 1.73e-22 - - - - - - - -
LGCOMDED_03156 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LGCOMDED_03157 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LGCOMDED_03158 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LGCOMDED_03159 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LGCOMDED_03160 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LGCOMDED_03161 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LGCOMDED_03162 6.98e-78 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
LGCOMDED_03163 7.81e-83 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
LGCOMDED_03164 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_03165 5.57e-310 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03166 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
LGCOMDED_03167 1.31e-269 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_03168 1.25e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
LGCOMDED_03169 7.52e-300 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LGCOMDED_03170 2.45e-23 - - - S - - - YrzO-like protein
LGCOMDED_03171 7.28e-218 yrdR - - EG - - - EamA-like transporter family
LGCOMDED_03172 2.83e-203 - - - K - - - Transcriptional regulator
LGCOMDED_03173 1.67e-251 trkA - - P ko:K07222 - ko00000 Oxidoreductase
LGCOMDED_03174 2.09e-213 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
LGCOMDED_03175 8.34e-86 yodA - - S - - - tautomerase
LGCOMDED_03176 2.43e-208 - - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
LGCOMDED_03177 2.03e-291 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
LGCOMDED_03178 2.79e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
LGCOMDED_03179 6.99e-116 azlC - - E - - - AzlC protein
LGCOMDED_03180 8.34e-104 bkdR - - K - - - helix_turn_helix ASNC type
LGCOMDED_03181 3.22e-54 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
LGCOMDED_03182 7.64e-290 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LGCOMDED_03184 4.27e-132 yrdC - - Q - - - Isochorismatase family
LGCOMDED_03185 2.28e-75 - - - S - - - Protein of unknown function (DUF2568)
LGCOMDED_03187 1.42e-118 yrdA - - S - - - DinB family
LGCOMDED_03188 2.86e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
LGCOMDED_03189 5.15e-247 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LGCOMDED_03190 8.38e-189 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
LGCOMDED_03191 2.29e-160 yrpD - - S - - - Domain of unknown function, YrpD
LGCOMDED_03193 1.04e-166 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LGCOMDED_03194 1.39e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_03195 2.43e-239 yrpG - - C - - - Aldo/keto reductase family
LGCOMDED_03196 9.19e-287 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
LGCOMDED_03197 2.97e-210 yraN - - K - - - Transcriptional regulator
LGCOMDED_03198 1.71e-262 yraM - - S - - - PrpF protein
LGCOMDED_03199 4.54e-19 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LGCOMDED_03200 9.4e-51 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_03201 2.15e-194 - - - S - - - Alpha beta hydrolase
LGCOMDED_03202 6.61e-80 - - - T - - - sh3 domain protein
LGCOMDED_03203 1.05e-81 - - - T - - - sh3 domain protein
LGCOMDED_03204 1.56e-85 - - - E - - - Glyoxalase-like domain
LGCOMDED_03205 1.2e-49 yraG - - - ko:K06440 - ko00000 -
LGCOMDED_03206 2.76e-83 yraF - - M - - - Spore coat protein
LGCOMDED_03207 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LGCOMDED_03208 6.11e-36 yraE - - - ko:K06440 - ko00000 -
LGCOMDED_03210 3.63e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
LGCOMDED_03211 5.46e-53 - - - - - - - -
LGCOMDED_03213 2.75e-244 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
LGCOMDED_03214 4.39e-05 - - - S - - - Nitrate reductase delta subunit
LGCOMDED_03215 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
LGCOMDED_03216 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
LGCOMDED_03217 1.93e-177 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LGCOMDED_03218 4.22e-211 - - - K - - - AraC-like ligand binding domain
LGCOMDED_03219 1.6e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LGCOMDED_03220 7.02e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
LGCOMDED_03221 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_03222 4.7e-197 ydeG - - EGP - - - Major facilitator superfamily
LGCOMDED_03223 3.19e-132 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
LGCOMDED_03224 2.67e-144 - - - - - - - -
LGCOMDED_03225 6.81e-41 - - - S - - - SNARE associated Golgi protein
LGCOMDED_03226 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
LGCOMDED_03227 4.22e-111 - - - K - - - Transcriptional regulator C-terminal region
LGCOMDED_03228 5.43e-196 ydeK - - EG - - - -transporter
LGCOMDED_03229 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_03230 3.68e-97 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
LGCOMDED_03231 2.81e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
LGCOMDED_03232 1.14e-69 - - - K - - - HxlR-like helix-turn-helix
LGCOMDED_03233 6.56e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LGCOMDED_03234 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
LGCOMDED_03235 2.78e-291 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGCOMDED_03236 4.33e-95 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LGCOMDED_03237 2.7e-189 - - - J - - - GNAT acetyltransferase
LGCOMDED_03238 7.68e-201 - - - EG - - - EamA-like transporter family
LGCOMDED_03239 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_03240 4.71e-148 ydfE - - S - - - Flavin reductase like domain
LGCOMDED_03241 2.13e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LGCOMDED_03242 3.92e-104 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LGCOMDED_03244 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03245 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_03246 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
LGCOMDED_03247 1.88e-223 - - - S - - - Alpha/beta hydrolase family
LGCOMDED_03248 2.27e-150 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
LGCOMDED_03249 1.96e-185 - - - K - - - Bacterial transcription activator, effector binding domain
LGCOMDED_03250 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
LGCOMDED_03251 1.58e-36 - - - - - - - -
LGCOMDED_03252 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
LGCOMDED_03253 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LGCOMDED_03254 0.0 ygaK - - C - - - Berberine and berberine like
LGCOMDED_03256 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
LGCOMDED_03257 2.93e-95 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LGCOMDED_03258 3.08e-67 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LGCOMDED_03259 8.45e-218 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
LGCOMDED_03260 5.86e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LGCOMDED_03261 3.13e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
LGCOMDED_03263 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LGCOMDED_03264 3.81e-100 ygaO - - - - - - -
LGCOMDED_03265 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03267 1.58e-146 yhzB - - S - - - B3/4 domain
LGCOMDED_03268 4.88e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGCOMDED_03269 4.41e-222 yhbB - - S - - - Putative amidase domain
LGCOMDED_03270 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LGCOMDED_03271 5.64e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
LGCOMDED_03272 3.77e-95 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LGCOMDED_03273 7.04e-104 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
LGCOMDED_03274 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
LGCOMDED_03275 1.72e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
LGCOMDED_03276 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
LGCOMDED_03277 1.09e-132 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
LGCOMDED_03278 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
LGCOMDED_03279 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
LGCOMDED_03280 3.95e-59 yhcC - - - - - - -
LGCOMDED_03281 2.92e-69 - - - - - - - -
LGCOMDED_03282 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03283 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_03284 6.47e-213 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_03285 3.45e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LGCOMDED_03286 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
LGCOMDED_03287 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
LGCOMDED_03288 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
LGCOMDED_03289 1.51e-300 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LGCOMDED_03290 6.58e-101 yoaW - - - - - - -
LGCOMDED_03291 4.14e-198 yoaV - - EG - - - EamA-like transporter family
LGCOMDED_03292 4.16e-201 yoaU - - K - - - LysR substrate binding domain
LGCOMDED_03293 7.76e-189 yoaT - - S - - - Protein of unknown function (DUF817)
LGCOMDED_03294 7.19e-41 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03295 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
LGCOMDED_03296 5.78e-215 yoaR - - V - - - vancomycin resistance protein
LGCOMDED_03297 2.35e-48 - - - - - - - -
LGCOMDED_03300 6.5e-65 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LGCOMDED_03301 1.45e-207 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
LGCOMDED_03303 4.69e-167 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
LGCOMDED_03304 3.94e-250 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
LGCOMDED_03305 7.3e-145 yoaK - - S - - - Membrane
LGCOMDED_03306 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
LGCOMDED_03307 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
LGCOMDED_03308 2.56e-228 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
LGCOMDED_03309 6.78e-61 - - - S - - - Protein of unknown function (DUF4025)
LGCOMDED_03310 1.46e-19 - - - - - - - -
LGCOMDED_03312 3.59e-45 yoaF - - - - - - -
LGCOMDED_03313 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LGCOMDED_03314 4.77e-234 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGCOMDED_03315 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
LGCOMDED_03316 7.48e-299 yoaB - - EGP - - - the major facilitator superfamily
LGCOMDED_03317 3.87e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_03318 3.01e-178 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
LGCOMDED_03319 5.07e-121 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LGCOMDED_03320 1.78e-167 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
LGCOMDED_03321 1.34e-121 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LGCOMDED_03322 1.09e-89 yoxB - - - - - - -
LGCOMDED_03323 3.84e-51 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
LGCOMDED_03324 7.94e-160 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
LGCOMDED_03325 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LGCOMDED_03326 3.18e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGCOMDED_03327 3.86e-261 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LGCOMDED_03328 9.68e-61 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03329 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
LGCOMDED_03330 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
LGCOMDED_03331 3.11e-98 yjbX - - S - - - Spore coat protein
LGCOMDED_03332 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
LGCOMDED_03333 8.04e-190 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
LGCOMDED_03334 1.45e-236 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LGCOMDED_03335 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LGCOMDED_03336 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
LGCOMDED_03337 8.96e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
LGCOMDED_03338 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
LGCOMDED_03339 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LGCOMDED_03340 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LGCOMDED_03341 6.65e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LGCOMDED_03342 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LGCOMDED_03343 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGCOMDED_03344 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
LGCOMDED_03345 1.87e-81 yjbL - - S - - - Belongs to the UPF0738 family
LGCOMDED_03346 7.32e-130 yjbK - - S - - - protein conserved in bacteria
LGCOMDED_03347 1.46e-128 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LGCOMDED_03348 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
LGCOMDED_03349 2.66e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
LGCOMDED_03351 2.68e-28 - - - - - - - -
LGCOMDED_03352 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
LGCOMDED_03353 6.66e-44 coiA - - S ko:K06198 - ko00000 Competence protein
LGCOMDED_03354 7.11e-222 coiA - - S ko:K06198 - ko00000 Competence protein
LGCOMDED_03355 4.65e-149 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LGCOMDED_03356 7.1e-144 yjbE - - P - - - Integral membrane protein TerC family
LGCOMDED_03357 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LGCOMDED_03358 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_03359 3.73e-257 yjbB - - EGP - - - Major Facilitator Superfamily
LGCOMDED_03360 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_03361 3.22e-248 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
LGCOMDED_03362 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGCOMDED_03363 1.03e-212 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGCOMDED_03364 3.77e-67 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LGCOMDED_03365 1.88e-305 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
LGCOMDED_03366 5.06e-234 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
LGCOMDED_03367 2.42e-262 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
LGCOMDED_03368 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LGCOMDED_03369 1.03e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
LGCOMDED_03370 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
LGCOMDED_03371 3.09e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
LGCOMDED_03372 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LGCOMDED_03373 2.09e-160 yfmS - - NT - - - chemotaxis protein
LGCOMDED_03374 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LGCOMDED_03375 6.88e-312 yfnA - - E ko:K03294 - ko00000 amino acid
LGCOMDED_03376 3.69e-168 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LGCOMDED_03377 2.94e-266 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_03378 3.19e-241 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
LGCOMDED_03379 6.42e-282 yfnE - - S - - - Glycosyltransferase like family 2
LGCOMDED_03380 1.1e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
LGCOMDED_03381 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
LGCOMDED_03382 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
LGCOMDED_03383 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LGCOMDED_03384 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
LGCOMDED_03385 2.38e-250 yetN - - S - - - Protein of unknown function (DUF3900)
LGCOMDED_03386 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
LGCOMDED_03387 1.18e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
LGCOMDED_03388 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
LGCOMDED_03389 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGCOMDED_03390 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LGCOMDED_03391 3.03e-166 yodH - - Q - - - Methyltransferase
LGCOMDED_03392 4.86e-41 yodI - - - - - - -
LGCOMDED_03393 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
LGCOMDED_03394 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
LGCOMDED_03395 2.08e-12 - - - - - - - -
LGCOMDED_03396 3.35e-71 yodL - - S - - - YodL-like
LGCOMDED_03397 2.23e-135 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
LGCOMDED_03398 5.18e-34 yozD - - S - - - YozD-like protein
LGCOMDED_03400 7.44e-159 yodN - - - - - - -
LGCOMDED_03401 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
LGCOMDED_03402 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
LGCOMDED_03403 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
LGCOMDED_03404 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
LGCOMDED_03405 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
LGCOMDED_03406 6.38e-151 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LGCOMDED_03408 4.15e-303 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LGCOMDED_03410 3.98e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
LGCOMDED_03411 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
LGCOMDED_03412 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
LGCOMDED_03413 2.18e-83 cgeA - - - ko:K06319 - ko00000 -
LGCOMDED_03414 1.15e-237 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
LGCOMDED_03415 5.44e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
LGCOMDED_03416 4.02e-82 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LGCOMDED_03418 9.96e-133 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LGCOMDED_03423 1.84e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LGCOMDED_03424 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03425 1.7e-282 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
LGCOMDED_03426 1.05e-22 - - - - - - - -
LGCOMDED_03427 2.86e-215 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
LGCOMDED_03428 3.71e-110 ykyB - - S - - - YkyB-like protein
LGCOMDED_03429 7.3e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
LGCOMDED_03430 4.8e-114 ykuD - - S - - - protein conserved in bacteria
LGCOMDED_03431 9.98e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
LGCOMDED_03432 1.06e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_03433 0.0 ybfG - - M - - - Putative peptidoglycan binding domain
LGCOMDED_03435 2.91e-297 ykuI - - T - - - Diguanylate phosphodiesterase
LGCOMDED_03437 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
LGCOMDED_03438 2.62e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
LGCOMDED_03439 7.83e-38 ykzF - - S - - - Antirepressor AbbA
LGCOMDED_03440 5.15e-100 ykuL - - S - - - CBS domain
LGCOMDED_03441 6.52e-216 ccpC - - K - - - Transcriptional regulator
LGCOMDED_03442 3.53e-110 - - - C ko:K03839 - ko00000 Flavodoxin domain
LGCOMDED_03443 1.01e-221 ykuO - - - - - - -
LGCOMDED_03444 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
LGCOMDED_03445 3.74e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LGCOMDED_03446 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LGCOMDED_03447 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
LGCOMDED_03448 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
LGCOMDED_03449 2.8e-129 ykuU - - O - - - Alkyl hydroperoxide reductase
LGCOMDED_03450 6.01e-104 ykuV - - CO - - - thiol-disulfide
LGCOMDED_03451 4.71e-122 rok - - K - - - Repressor of ComK
LGCOMDED_03452 0.0 ybeC - - E - - - amino acid
LGCOMDED_03453 9.95e-211 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
LGCOMDED_03454 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
LGCOMDED_03455 1.7e-45 - - - S - - - Protein of unknown function (DUF2651)
LGCOMDED_03456 2.35e-215 ybfA - - K - - - FR47-like protein
LGCOMDED_03457 7.54e-284 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
LGCOMDED_03459 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
LGCOMDED_03460 4.15e-205 ybfH - - EG - - - EamA-like transporter family
LGCOMDED_03461 1.23e-186 ybfI - - K - - - AraC-like ligand binding domain
LGCOMDED_03462 6.26e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LGCOMDED_03463 1.69e-228 mpr - - M - - - Belongs to the peptidase S1B family
LGCOMDED_03465 1.71e-208 - - - S - - - Alpha/beta hydrolase family
LGCOMDED_03466 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGCOMDED_03467 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
LGCOMDED_03468 2.5e-189 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LGCOMDED_03469 3.88e-60 ybfN - - - - - - -
LGCOMDED_03470 9.32e-316 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
LGCOMDED_03471 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
LGCOMDED_03472 1.73e-272 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LGCOMDED_03473 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_03474 2.48e-173 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LGCOMDED_03475 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
LGCOMDED_03477 3.18e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
LGCOMDED_03478 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
LGCOMDED_03479 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
LGCOMDED_03481 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
LGCOMDED_03482 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
LGCOMDED_03483 6.85e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03484 2.34e-215 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
LGCOMDED_03485 7.94e-220 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
LGCOMDED_03486 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LGCOMDED_03487 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_03488 5.89e-117 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LGCOMDED_03489 3.49e-187 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
LGCOMDED_03490 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
LGCOMDED_03491 1.58e-84 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LGCOMDED_03492 8.78e-96 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
LGCOMDED_03493 1.34e-121 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LGCOMDED_03494 1.92e-67 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
LGCOMDED_03495 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
LGCOMDED_03496 2.44e-216 eamA1 - - EG - - - spore germination
LGCOMDED_03497 9.12e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_03498 3.69e-99 ycbM - - T - - - Histidine kinase
LGCOMDED_03499 1.25e-98 ycbM - - T - - - Histidine kinase
LGCOMDED_03500 1.94e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_03501 4.75e-147 - - - S - - - ABC-2 family transporter protein
LGCOMDED_03502 2.21e-76 ycbP - - S - - - Protein of unknown function (DUF2512)
LGCOMDED_03503 2.05e-99 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
LGCOMDED_03504 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
LGCOMDED_03505 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
LGCOMDED_03506 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LGCOMDED_03507 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGCOMDED_03508 2.32e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LGCOMDED_03509 5.67e-258 ycbU - - E - - - Selenocysteine lyase
LGCOMDED_03510 2.39e-300 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
LGCOMDED_03511 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
LGCOMDED_03512 2.3e-255 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LGCOMDED_03513 4.67e-146 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
LGCOMDED_03514 6.61e-73 - - - S - - - RDD family
LGCOMDED_03515 5.86e-254 yccF - - K ko:K07039 - ko00000 SEC-C motif
LGCOMDED_03516 6.44e-83 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LGCOMDED_03517 4.34e-71 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
LGCOMDED_03518 3.81e-160 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
LGCOMDED_03519 8.97e-170 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
LGCOMDED_03520 1.09e-254 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
LGCOMDED_03521 2.77e-221 yccK - - C - - - Aldo keto reductase
LGCOMDED_03522 2.24e-240 ycdA - - S - - - Domain of unknown function (DUF5105)
LGCOMDED_03523 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_03524 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_03525 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
LGCOMDED_03526 6.95e-159 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LGCOMDED_03527 2.93e-45 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
LGCOMDED_03528 3.96e-179 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
LGCOMDED_03529 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LGCOMDED_03530 1.31e-219 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
LGCOMDED_03531 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LGCOMDED_03532 2.2e-171 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LGCOMDED_03533 1.99e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGCOMDED_03534 1.78e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
LGCOMDED_03535 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LGCOMDED_03536 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
LGCOMDED_03537 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
LGCOMDED_03538 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
LGCOMDED_03539 2.96e-245 yceH - - P - - - Belongs to the TelA family
LGCOMDED_03540 5.45e-278 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
LGCOMDED_03541 2.9e-258 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
LGCOMDED_03542 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
LGCOMDED_03543 5.2e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
LGCOMDED_03544 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LGCOMDED_03545 8.18e-210 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
LGCOMDED_03546 9.35e-275 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
LGCOMDED_03547 0.0 ycgA - - S - - - Membrane
LGCOMDED_03548 9.08e-104 ycgB - - - - - - -
LGCOMDED_03549 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LGCOMDED_03550 4.16e-120 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
LGCOMDED_03551 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
LGCOMDED_03552 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LGCOMDED_03553 3.44e-191 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
LGCOMDED_03554 8.51e-193 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
LGCOMDED_03555 5.98e-120 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
LGCOMDED_03556 3.03e-190 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LGCOMDED_03557 3.46e-111 tmrB - - S - - - AAA domain
LGCOMDED_03558 4.28e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGCOMDED_03559 1.45e-183 - - - Q - - - ubiE/COQ5 methyltransferase family
LGCOMDED_03560 8.35e-230 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
LGCOMDED_03561 6.64e-233 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
LGCOMDED_03562 7.76e-187 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
LGCOMDED_03563 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
LGCOMDED_03564 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
LGCOMDED_03565 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGCOMDED_03566 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
LGCOMDED_03567 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
LGCOMDED_03568 2.41e-184 ycgR - - S ko:K07089 - ko00000 permeases
LGCOMDED_03569 2.95e-203 ycgS - - I - - - alpha/beta hydrolase fold
LGCOMDED_03570 2.25e-240 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
LGCOMDED_03571 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
LGCOMDED_03572 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
LGCOMDED_03573 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGCOMDED_03574 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LGCOMDED_03575 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
LGCOMDED_03576 1.11e-282 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
LGCOMDED_03577 2.47e-221 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
LGCOMDED_03578 1.47e-131 - - - M - - - ErfK YbiS YcfS YnhG
LGCOMDED_03579 2.72e-141 yciC - - S - - - GTPases (G3E family)
LGCOMDED_03580 2.26e-123 yciC - - S - - - GTPases (G3E family)
LGCOMDED_03581 5.79e-147 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LGCOMDED_03582 6.23e-186 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LGCOMDED_03583 4.14e-62 yckC - - S - - - membrane
LGCOMDED_03584 1.01e-68 yckD - - S - - - Protein of unknown function (DUF2680)
LGCOMDED_03585 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LGCOMDED_03586 9.65e-91 nin - - S - - - Competence protein J (ComJ)
LGCOMDED_03587 2.28e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
LGCOMDED_03588 4.34e-267 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_03589 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
LGCOMDED_03590 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
LGCOMDED_03591 5.93e-85 hxlR - - K - - - transcriptional
LGCOMDED_03592 8.11e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LGCOMDED_03593 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
LGCOMDED_03594 1.07e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_03595 5.86e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
LGCOMDED_03596 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03597 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGCOMDED_03598 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
LGCOMDED_03599 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
LGCOMDED_03600 2.79e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
LGCOMDED_03602 2.69e-229 ykvZ - - K - - - Transcriptional regulator
LGCOMDED_03603 9.15e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LGCOMDED_03604 3.99e-09 - - - - - - - -
LGCOMDED_03605 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
LGCOMDED_03606 1.12e-114 stoA - - CO - - - thiol-disulfide
LGCOMDED_03607 1.12e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LGCOMDED_03608 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
LGCOMDED_03609 2.6e-39 - - - - - - - -
LGCOMDED_03610 5.43e-35 ykvS - - S - - - protein conserved in bacteria
LGCOMDED_03611 2.2e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
LGCOMDED_03612 2.72e-46 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LGCOMDED_03613 1.04e-113 - - - L - - - Belongs to the 'phage' integrase family
LGCOMDED_03614 4.47e-56 - - - - - - - -
LGCOMDED_03615 1.01e-312 - - - I - - - Pfam Lipase (class 3)
LGCOMDED_03616 5.57e-48 - - - S - - - Protein of unknown function (DUF1433)
LGCOMDED_03617 7.57e-60 - - - S - - - Protein of unknown function (DUF1433)
LGCOMDED_03620 1.18e-60 - - - - - - - -
LGCOMDED_03621 2.69e-28 - - - - - - - -
LGCOMDED_03624 1.12e-126 - 3.1.4.46, 5.4.2.11 - C ko:K01126,ko:K01834 ko00010,ko00260,ko00564,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00564,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 glycerophosphoryl diester phosphodiesterase
LGCOMDED_03625 4.82e-72 - - - - - - - -
LGCOMDED_03626 1.05e-75 - - - - - - - -
LGCOMDED_03627 2.64e-242 - - - A - - - Belongs to the 'phage' integrase family
LGCOMDED_03629 1.04e-64 - - - - - - - -
LGCOMDED_03630 0.0 - - - S - - - peptidoglycan catabolic process
LGCOMDED_03631 3.07e-109 - - - S - - - Phage tail protein
LGCOMDED_03632 0.0 - - - S - - - Pfam Transposase IS66
LGCOMDED_03633 1.39e-169 - - - - - - - -
LGCOMDED_03634 2.63e-282 - - - M - - - Pectate lyase superfamily protein
LGCOMDED_03639 2.11e-97 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
LGCOMDED_03640 4.78e-38 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGCOMDED_03641 0.000401 - - - - - - - -
LGCOMDED_03642 3.18e-129 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGCOMDED_03643 5.88e-73 - - - S - - - Protein of unknown function (DUF1140)
LGCOMDED_03644 1.26e-288 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGCOMDED_03645 2.45e-24 - - - S - - - sequence-specific DNA binding transcription factor activity
LGCOMDED_03646 5.48e-155 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGCOMDED_03647 5.24e-85 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
LGCOMDED_03651 1.8e-97 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
LGCOMDED_03662 3.26e-202 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
LGCOMDED_03665 5.53e-106 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
LGCOMDED_03670 2.08e-151 - - - S - - - protein conserved in bacteria
LGCOMDED_03671 6.77e-07 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGCOMDED_03672 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
LGCOMDED_03673 5.46e-74 ygzB - - S - - - UPF0295 protein
LGCOMDED_03674 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
LGCOMDED_03675 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
LGCOMDED_03676 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
LGCOMDED_03677 3.61e-236 ygaE - - S - - - Membrane
LGCOMDED_03678 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
LGCOMDED_03679 1.64e-135 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
LGCOMDED_03680 1.88e-63 ygaB - - S - - - YgaB-like protein
LGCOMDED_03681 9.51e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
LGCOMDED_03682 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_03683 1.73e-48 yfhS - - - - - - -
LGCOMDED_03684 2.26e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
LGCOMDED_03685 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
LGCOMDED_03686 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
LGCOMDED_03687 6.93e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LGCOMDED_03688 1.87e-216 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
LGCOMDED_03689 1.81e-65 yfhL - - S - - - SdpI/YhfL protein family
LGCOMDED_03690 3.58e-119 yfhK - - T - - - Bacterial SH3 domain homologues
LGCOMDED_03691 2.39e-235 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
LGCOMDED_03692 6.69e-263 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
LGCOMDED_03693 4.42e-164 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
LGCOMDED_03694 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
LGCOMDED_03695 2.91e-295 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
LGCOMDED_03696 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGCOMDED_03697 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
LGCOMDED_03698 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
LGCOMDED_03699 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
LGCOMDED_03700 7.55e-44 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
LGCOMDED_03701 2.12e-163 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03702 1.19e-23 - - - - - - - -
LGCOMDED_03703 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
LGCOMDED_03706 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LGCOMDED_03707 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
LGCOMDED_03708 1.74e-119 yobW - - - - - - -
LGCOMDED_03709 6.31e-224 yobV - - K - - - WYL domain
LGCOMDED_03710 4.8e-111 - - - K - - - Bacterial transcription activator, effector binding domain
LGCOMDED_03711 3.16e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
LGCOMDED_03712 8.85e-127 yobS - - K - - - Transcriptional regulator
LGCOMDED_03713 5.67e-178 - - - J - - - FR47-like protein
LGCOMDED_03714 8.68e-174 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
LGCOMDED_03715 8.66e-70 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
LGCOMDED_03716 2.76e-283 yobO - - M - - - Pectate lyase superfamily protein
LGCOMDED_03717 3.89e-248 yobO - - M - - - Pectate lyase superfamily protein
LGCOMDED_03718 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
LGCOMDED_03719 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
LGCOMDED_03720 0.0 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
LGCOMDED_03721 9.26e-123 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
LGCOMDED_03722 2.21e-104 yokK - - S - - - SMI1 / KNR4 family
LGCOMDED_03723 4.92e-139 lin0465 - - S - - - DJ-1/PfpI family
LGCOMDED_03724 1.37e-255 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
LGCOMDED_03725 9.37e-21 ytcD - - K - - - Transcriptional regulator
LGCOMDED_03726 8.75e-55 ytcD - - K - - - Transcriptional regulator
LGCOMDED_03727 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LGCOMDED_03728 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LGCOMDED_03729 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGCOMDED_03730 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
LGCOMDED_03731 1.05e-221 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
LGCOMDED_03732 9.37e-142 ytxB - - S - - - SNARE associated Golgi protein
LGCOMDED_03733 5.74e-204 ytxC - - S - - - YtxC-like family
LGCOMDED_03735 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LGCOMDED_03736 6.64e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
LGCOMDED_03737 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03738 3.39e-167 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
LGCOMDED_03739 2.08e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LGCOMDED_03740 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LGCOMDED_03741 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
LGCOMDED_03742 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
LGCOMDED_03743 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGCOMDED_03744 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LGCOMDED_03745 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LGCOMDED_03746 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LGCOMDED_03747 2.3e-124 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
LGCOMDED_03748 2.74e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
LGCOMDED_03749 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
LGCOMDED_03750 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
LGCOMDED_03752 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGCOMDED_03753 1.66e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LGCOMDED_03754 5.26e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LGCOMDED_03755 1.24e-314 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
LGCOMDED_03756 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LGCOMDED_03757 2.45e-230 yaaC - - S - - - YaaC-like Protein
LGCOMDED_03758 2.35e-295 - - - M - - - nucleic acid phosphodiester bond hydrolysis
LGCOMDED_03760 3.72e-38 - - - - - - - -
LGCOMDED_03761 4.41e-24 - - - - - - - -
LGCOMDED_03763 6.07e-273 yjcL - - S - - - Protein of unknown function (DUF819)
LGCOMDED_03764 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
LGCOMDED_03765 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LGCOMDED_03766 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
LGCOMDED_03767 1.91e-177 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
LGCOMDED_03768 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
LGCOMDED_03769 1.1e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_03770 6.31e-51 - - - - - - - -
LGCOMDED_03771 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
LGCOMDED_03772 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
LGCOMDED_03775 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
LGCOMDED_03776 1.44e-72 cotV - - S ko:K06340 - ko00000 Spore Coat Protein X and V domain
LGCOMDED_03777 9.52e-51 cotW - - - ko:K06341 - ko00000 -
LGCOMDED_03778 0.0 ydaB - - IQ - - - acyl-CoA ligase
LGCOMDED_03779 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
LGCOMDED_03780 3.5e-219 ycsN - - S - - - Oxidoreductase
LGCOMDED_03781 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
LGCOMDED_03782 2.2e-65 yczJ - - S - - - biosynthesis
LGCOMDED_03784 1.7e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
LGCOMDED_03785 1.55e-170 kipR - - K - - - Transcriptional regulator
LGCOMDED_03786 2.6e-234 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
LGCOMDED_03787 1.19e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
LGCOMDED_03788 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
LGCOMDED_03789 1.13e-272 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
LGCOMDED_03790 3.82e-181 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
LGCOMDED_03791 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
LGCOMDED_03793 2.11e-253 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
LGCOMDED_03794 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_03795 0.0 yhjG - - CH - - - FAD binding domain
LGCOMDED_03796 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
LGCOMDED_03797 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
LGCOMDED_03798 4.13e-78 yhjD - - - - - - -
LGCOMDED_03799 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
LGCOMDED_03800 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGCOMDED_03801 1.68e-55 yhjA - - S - - - Excalibur calcium-binding domain
LGCOMDED_03802 1.16e-212 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
LGCOMDED_03803 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
LGCOMDED_03804 9.84e-45 yhzC - - S - - - IDEAL
LGCOMDED_03805 1.51e-201 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_03806 4.25e-232 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LGCOMDED_03807 1.67e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
LGCOMDED_03808 1.02e-257 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
LGCOMDED_03809 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
LGCOMDED_03810 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LGCOMDED_03811 8.58e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LGCOMDED_03812 3.93e-140 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
LGCOMDED_03813 1.79e-219 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
LGCOMDED_03814 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
LGCOMDED_03815 1.47e-100 - - - K - - - acetyltransferase
LGCOMDED_03816 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
LGCOMDED_03817 4.39e-304 yhfN - - O - - - Peptidase M48
LGCOMDED_03818 2.78e-85 yhfM - - - - - - -
LGCOMDED_03819 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
LGCOMDED_03820 2.13e-143 yhfK - - GM - - - NmrA-like family
LGCOMDED_03821 8.2e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
LGCOMDED_03822 4.01e-181 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LGCOMDED_03823 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LGCOMDED_03824 1.53e-93 - - - S - - - ASCH
LGCOMDED_03825 1.55e-252 yhfE - - G - - - peptidase M42
LGCOMDED_03826 1.88e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
LGCOMDED_03827 2.07e-235 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGCOMDED_03828 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
LGCOMDED_03829 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03830 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGCOMDED_03831 3.41e-231 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
LGCOMDED_03832 9.08e-260 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGCOMDED_03833 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
LGCOMDED_03834 1.08e-117 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
LGCOMDED_03835 8.58e-46 - - - C - - - Rubrerythrin
LGCOMDED_03836 3.29e-313 yhfA - - C - - - membrane
LGCOMDED_03837 1.32e-292 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LGCOMDED_03838 7.1e-162 ecsC - - S - - - EcsC protein family
LGCOMDED_03839 8.53e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
LGCOMDED_03840 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
LGCOMDED_03841 1.43e-105 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LGCOMDED_03842 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LGCOMDED_03843 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
LGCOMDED_03844 1.88e-54 yhaH - - S - - - YtxH-like protein
LGCOMDED_03845 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
LGCOMDED_03846 8.48e-73 yhaI - - S - - - Protein of unknown function (DUF1878)
LGCOMDED_03847 1.4e-116 yhaK - - S - - - Putative zincin peptidase
LGCOMDED_03848 3.85e-160 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LGCOMDED_03849 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
LGCOMDED_03850 2.13e-227 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
LGCOMDED_03851 0.0 yhaN - - L - - - AAA domain
LGCOMDED_03852 6.11e-297 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
LGCOMDED_03853 1.72e-270 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
LGCOMDED_03854 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_03855 9.36e-36 - - - S - - - YhzD-like protein
LGCOMDED_03856 3.62e-169 yhaR - - I - - - enoyl-CoA hydratase
LGCOMDED_03858 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
LGCOMDED_03859 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
LGCOMDED_03860 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
LGCOMDED_03861 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
LGCOMDED_03862 3.71e-261 yhaZ - - L - - - DNA alkylation repair enzyme
LGCOMDED_03863 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
LGCOMDED_03864 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
LGCOMDED_03865 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
LGCOMDED_03866 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
LGCOMDED_03867 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
LGCOMDED_03868 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
LGCOMDED_03869 1.84e-140 yheG - - GM - - - NAD(P)H-binding
LGCOMDED_03870 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LGCOMDED_03871 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
LGCOMDED_03872 1.86e-109 nhaX - - T - - - Belongs to the universal stress protein A family
LGCOMDED_03873 3.77e-305 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
LGCOMDED_03874 3.16e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LGCOMDED_03875 2.14e-195 nodB1 - - G - - - deacetylase
LGCOMDED_03876 1.19e-179 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LGCOMDED_03877 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
LGCOMDED_03878 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
LGCOMDED_03879 1.5e-171 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LGCOMDED_03880 2.78e-85 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LGCOMDED_03881 5.01e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LGCOMDED_03882 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
LGCOMDED_03883 8.45e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
LGCOMDED_03884 4.07e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
LGCOMDED_03885 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LGCOMDED_03886 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LGCOMDED_03887 9.18e-242 yhdN - - C - - - Aldo keto reductase
LGCOMDED_03888 1.08e-111 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
LGCOMDED_03889 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
LGCOMDED_03890 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
LGCOMDED_03891 2.91e-99 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LGCOMDED_03892 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LGCOMDED_03893 4.29e-310 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LGCOMDED_03894 5.36e-316 yhdG - - E ko:K03294 - ko00000 amino acid
LGCOMDED_03895 2.25e-205 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LGCOMDED_03896 1.76e-259 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LGCOMDED_03897 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_03898 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LGCOMDED_03899 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
LGCOMDED_03900 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
LGCOMDED_03901 1.02e-304 ygxB - - M - - - Conserved TM helix
LGCOMDED_03902 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
LGCOMDED_03903 4.53e-270 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
LGCOMDED_03904 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
LGCOMDED_03905 1.65e-51 yhdB - - S - - - YhdB-like protein
LGCOMDED_03906 1.34e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
LGCOMDED_03907 5.67e-146 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_03908 1.27e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_03909 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
LGCOMDED_03910 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGCOMDED_03911 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGCOMDED_03912 1.1e-193 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
LGCOMDED_03913 4.4e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LGCOMDED_03914 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LGCOMDED_03915 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LGCOMDED_03916 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
LGCOMDED_03917 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
LGCOMDED_03918 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
LGCOMDED_03919 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
LGCOMDED_03920 4.89e-132 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
LGCOMDED_03921 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
LGCOMDED_03922 9.06e-142 yhcQ - - M - - - Spore coat protein
LGCOMDED_03923 1.18e-216 yhcP - - - - - - -
LGCOMDED_03924 1.9e-95 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LGCOMDED_03925 2.4e-72 yhcM - - - - - - -
LGCOMDED_03926 6.41e-75 - - - - - - - -
LGCOMDED_03927 8.92e-115 - - - - - - - -
LGCOMDED_03928 1.06e-100 - - - - - - - -
LGCOMDED_03929 9.48e-157 - - - - - - - -
LGCOMDED_03931 5.19e-90 - - - - - - - -
LGCOMDED_03932 2.31e-105 - - - - - - - -
LGCOMDED_03933 3.43e-236 - - - - - - - -
LGCOMDED_03934 7.15e-122 - - - - - - - -
LGCOMDED_03935 0.0 - - - - - - - -
LGCOMDED_03936 0.0 - - - - - - - -
LGCOMDED_03937 0.0 - - - S - - - Terminase-like family
LGCOMDED_03938 8.62e-223 - - - - - - - -
LGCOMDED_03942 1.66e-269 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
LGCOMDED_03944 2.04e-275 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
LGCOMDED_03945 4.3e-259 cotI - - S ko:K06331 - ko00000 Spore coat protein
LGCOMDED_03946 1.97e-101 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
LGCOMDED_03947 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LGCOMDED_03948 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
LGCOMDED_03949 6.43e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
LGCOMDED_03950 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGCOMDED_03951 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGCOMDED_03959 1.44e-68 - - - S - - - YolD-like protein
LGCOMDED_03960 1.11e-301 - - - S - - - damaged DNA binding
LGCOMDED_03963 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 Peptidase C39 family
LGCOMDED_03964 3.44e-91 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 cell redox homeostasis
LGCOMDED_03965 6.04e-309 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
LGCOMDED_03966 5.12e-96 - - - O ko:K03611 - ko00000,ko03110 protein disulfide oxidoreductase activity
LGCOMDED_03967 3.04e-53 - - - S - - - SPP1 phage holin
LGCOMDED_03968 1.42e-43 bhlA - - S - - - BhlA holin family
LGCOMDED_03969 4.3e-256 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 Ami_2
LGCOMDED_03970 2.16e-111 - - - - - - - -
LGCOMDED_03971 3.58e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
LGCOMDED_03972 1.2e-122 - - - M - - - FR47-like protein
LGCOMDED_03973 4.54e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
LGCOMDED_03974 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
LGCOMDED_03975 6.53e-108 yuaE - - S - - - DinB superfamily
LGCOMDED_03976 5.57e-135 yuaD - - - - - - -
LGCOMDED_03977 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
LGCOMDED_03978 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
LGCOMDED_03979 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
LGCOMDED_03980 5.83e-118 yuaB - - - - - - -
LGCOMDED_03982 3.08e-283 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LGCOMDED_03983 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
LGCOMDED_03984 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
LGCOMDED_03985 8.3e-274 xylR - - GK - - - ROK family
LGCOMDED_03986 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
LGCOMDED_03987 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
LGCOMDED_03989 6.59e-119 rapE - - S ko:K06363 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
LGCOMDED_03991 6.75e-95 - - - K - - - Transcriptional regulator
LGCOMDED_03992 1.02e-212 pre - - D - - - plasmid recombination enzyme
LGCOMDED_03993 1.01e-48 - - - S - - - Uncharacterised protein family (UPF0715)
LGCOMDED_03994 1.08e-213 - - - S - - - Protein of unknown function (DUF3238)
LGCOMDED_03995 3.1e-144 - - - L - - - Replication protein
LGCOMDED_03996 3.67e-126 - - - S - - - Protein of unknown function (DUF421)
LGCOMDED_03997 0.0 - - - I - - - PLD-like domain
LGCOMDED_03998 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
LGCOMDED_03999 1.38e-16 - - - S - - - Protein of unknown function (DUF421)
LGCOMDED_04000 9.32e-192 - - - S - - - membrane
LGCOMDED_04001 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
LGCOMDED_04002 1.77e-74 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
LGCOMDED_04003 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
LGCOMDED_04004 4.11e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
LGCOMDED_04005 4.82e-103 - - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LGCOMDED_04006 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
LGCOMDED_04007 5.47e-117 - - - P - - - Catalase
LGCOMDED_04008 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LGCOMDED_04009 2.56e-220 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LGCOMDED_04010 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGCOMDED_04011 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGCOMDED_04012 4.32e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGCOMDED_04013 1.77e-32 yqzJ - - - - - - -
LGCOMDED_04014 1.03e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LGCOMDED_04015 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
LGCOMDED_04016 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
LGCOMDED_04017 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LGCOMDED_04018 4.62e-29 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LGCOMDED_04019 7.24e-205 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
LGCOMDED_04020 8.57e-222 ywtF_2 - - K - - - Transcriptional regulator
LGCOMDED_04021 2.61e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
LGCOMDED_04022 1.25e-263 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
LGCOMDED_04023 2.86e-246 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
LGCOMDED_04024 0.0 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
LGCOMDED_04025 1.3e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
LGCOMDED_04026 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LGCOMDED_04027 0.0 - - - - - - - -
LGCOMDED_04028 3.8e-273 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGCOMDED_04029 1.9e-185 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LGCOMDED_04030 3.82e-91 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
LGCOMDED_04031 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferase 1 domain A
LGCOMDED_04032 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LGCOMDED_04033 2.06e-194 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
LGCOMDED_04034 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LGCOMDED_04035 2.13e-127 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LGCOMDED_04036 5.43e-05 - 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase-like
LGCOMDED_04037 0.0 - - - M - - - Glycosyltransferase like family 2
LGCOMDED_04038 0.0 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LGCOMDED_04039 2.53e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
LGCOMDED_04040 2.58e-275 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LGCOMDED_04041 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LGCOMDED_04042 3.26e-50 - - - - - - - -
LGCOMDED_04043 0.0 lytB - - D - - - Stage II sporulation protein
LGCOMDED_04044 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
LGCOMDED_04045 1.49e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LGCOMDED_04046 3.44e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LGCOMDED_04047 1.63e-278 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
LGCOMDED_04048 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LGCOMDED_04049 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
LGCOMDED_04050 2.02e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
LGCOMDED_04051 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LGCOMDED_04052 2.49e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
LGCOMDED_04053 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LGCOMDED_04054 2.68e-223 yvhJ - - K - - - Transcriptional regulator
LGCOMDED_04055 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
LGCOMDED_04056 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LGCOMDED_04057 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_04058 1.77e-198 degV - - S - - - protein conserved in bacteria
LGCOMDED_04059 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LGCOMDED_04060 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
LGCOMDED_04061 9.99e-166 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
LGCOMDED_04062 1.83e-96 yvyF - - S - - - flagellar protein
LGCOMDED_04063 1.06e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
LGCOMDED_04064 3.5e-102 yvyG - - NOU - - - FlgN protein
LGCOMDED_04065 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
LGCOMDED_04066 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
LGCOMDED_04067 1.7e-92 yviE - - - - - - -
LGCOMDED_04068 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LGCOMDED_04069 4.29e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGCOMDED_04070 7.45e-148 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LGCOMDED_04071 9.77e-71 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
LGCOMDED_04072 2.21e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LGCOMDED_04073 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
LGCOMDED_04074 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
LGCOMDED_04075 2.46e-67 - - - - - - - -
LGCOMDED_04076 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGCOMDED_04077 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LGCOMDED_04078 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LGCOMDED_04079 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LGCOMDED_04080 3.23e-75 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
LGCOMDED_04081 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
LGCOMDED_04082 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LGCOMDED_04083 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
LGCOMDED_04084 1.38e-73 swrA - - S - - - Swarming motility protein
LGCOMDED_04085 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGCOMDED_04086 5.24e-296 yvkA - - P - - - -transporter
LGCOMDED_04087 4.77e-130 yvkB - - K - - - Transcriptional regulator
LGCOMDED_04088 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
LGCOMDED_04089 2.54e-42 csbA - - S - - - protein conserved in bacteria
LGCOMDED_04090 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LGCOMDED_04091 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LGCOMDED_04092 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LGCOMDED_04093 2.25e-45 yvkN - - - - - - -
LGCOMDED_04094 8.09e-65 yvlA - - - - - - -
LGCOMDED_04095 9.59e-220 yvlB - - S - - - Putative adhesin
LGCOMDED_04096 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
LGCOMDED_04097 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
LGCOMDED_04098 4.26e-272 yvmA - - EGP - - - Major Facilitator Superfamily
LGCOMDED_04099 8.46e-112 yvmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_04100 8.35e-176 yvmC 2.3.2.22 - S ko:K17485 - ko00000,ko01000 Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LGCOMDED_04101 3.49e-290 cypX 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
LGCOMDED_04102 7.73e-109 yvnA - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_04103 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
LGCOMDED_04104 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
LGCOMDED_04105 2.58e-167 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LGCOMDED_04106 2.51e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGCOMDED_04107 1.47e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LGCOMDED_04108 1.29e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGCOMDED_04109 3.05e-210 yvoD - - P - - - COG0370 Fe2 transport system protein B
LGCOMDED_04110 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LGCOMDED_04111 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LGCOMDED_04112 3.15e-153 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
LGCOMDED_04113 2.49e-178 yvpB - - NU - - - protein conserved in bacteria
LGCOMDED_04114 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LGCOMDED_04115 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LGCOMDED_04116 1.74e-290 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGCOMDED_04117 1.17e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
LGCOMDED_04118 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGCOMDED_04119 2.67e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGCOMDED_04120 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LGCOMDED_04121 3.05e-145 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
LGCOMDED_04122 3.53e-169 - - - - - - - -
LGCOMDED_04123 0.0 - - - - - - - -
LGCOMDED_04125 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
LGCOMDED_04127 1.42e-09 - - - S - - - YolD-like protein
LGCOMDED_04128 1.92e-47 - - - - - - - -
LGCOMDED_04129 2.77e-26 - - - - - - - -
LGCOMDED_04130 1.72e-23 - - - - - - - -
LGCOMDED_04131 1.27e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
LGCOMDED_04132 2.81e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
LGCOMDED_04133 0.000141 - - - - - - - -
LGCOMDED_04134 6.93e-67 yjdF3 - - S - - - Protein of unknown function (DUF2992)
LGCOMDED_04135 4.96e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
LGCOMDED_04136 3.2e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
LGCOMDED_04137 1.7e-262 yrkH - - P - - - Rhodanese Homology Domain
LGCOMDED_04138 7.04e-22 perX - - S - - - DsrE/DsrF-like family
LGCOMDED_04139 6.82e-128 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
LGCOMDED_04140 1.96e-108 yrkE - - O - - - DsrE/DsrF/DrsH-like family
LGCOMDED_04141 4.38e-52 yrkD - - S - - - protein conserved in bacteria
LGCOMDED_04142 3.32e-28 - - - - - - - -
LGCOMDED_04143 4.11e-134 yrkC - - G - - - Cupin domain
LGCOMDED_04144 3.52e-106 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
LGCOMDED_04145 1.18e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGCOMDED_04146 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
LGCOMDED_04147 2.31e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
LGCOMDED_04148 4.36e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LGCOMDED_04150 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
LGCOMDED_04151 3.23e-171 - - - M - - - Membrane
LGCOMDED_04152 5.07e-38 yetM - - CH - - - FAD binding domain
LGCOMDED_04153 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
LGCOMDED_04154 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
LGCOMDED_04155 1.97e-54 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LGCOMDED_04156 1.11e-113 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LGCOMDED_04157 2.61e-49 - - - - - - - -
LGCOMDED_04158 3.51e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LGCOMDED_04159 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
LGCOMDED_04160 1.44e-196 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
LGCOMDED_04161 2.08e-87 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
LGCOMDED_04162 5.17e-149 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 Multidrug transporter MatE
LGCOMDED_04163 1.94e-145 tetR3 - - K ko:K18476 - ko00000,ko00002,ko03000 Transcriptional regulator
LGCOMDED_04164 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LGCOMDED_04165 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LGCOMDED_04166 0.0 rocB - - E - - - arginine degradation protein
LGCOMDED_04167 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
LGCOMDED_04168 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGCOMDED_04172 2.88e-56 - - - M - - - D-alanyl-D-alanine carboxypeptidase
LGCOMDED_04173 4.76e-15 - - - K - - - Helix-turn-helix XRE-family like proteins
LGCOMDED_04174 2.45e-268 yttB - - EGP - - - Major facilitator superfamily
LGCOMDED_04175 2.02e-78 yttA - - S - - - Pfam Transposase IS66
LGCOMDED_04176 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
LGCOMDED_04177 7.53e-137 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LGCOMDED_04178 3.25e-253 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
LGCOMDED_04179 2.9e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
LGCOMDED_04180 1.63e-206 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
LGCOMDED_04181 5.96e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
LGCOMDED_04182 3.48e-255 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
LGCOMDED_04183 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
LGCOMDED_04184 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
LGCOMDED_04185 1.1e-193 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LGCOMDED_04186 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LGCOMDED_04187 1.32e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LGCOMDED_04188 6.42e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
LGCOMDED_04189 6.85e-146 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
LGCOMDED_04190 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
LGCOMDED_04191 1.48e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LGCOMDED_04192 5.69e-44 yvfG - - S - - - YvfG protein
LGCOMDED_04193 1.46e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
LGCOMDED_04194 9.08e-280 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
LGCOMDED_04195 2.88e-77 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
LGCOMDED_04196 9.14e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LGCOMDED_04197 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LGCOMDED_04198 3.75e-243 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
LGCOMDED_04199 1.06e-256 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
LGCOMDED_04200 1.66e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
LGCOMDED_04201 2.08e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
LGCOMDED_04202 7.18e-278 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
LGCOMDED_04203 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
LGCOMDED_04204 3.85e-282 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
LGCOMDED_04205 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
LGCOMDED_04206 3.23e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
LGCOMDED_04207 1.32e-156 epsA - - M ko:K19420 - ko00000 biosynthesis protein
LGCOMDED_04208 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
LGCOMDED_04209 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
LGCOMDED_04211 3.13e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
LGCOMDED_04212 1.23e-93 - - - S - - - Protein of unknown function (DUF3237)
LGCOMDED_04213 8.37e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
LGCOMDED_04214 0.0 pbpE - - V - - - Beta-lactamase
LGCOMDED_04215 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
LGCOMDED_04216 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
LGCOMDED_04217 0.0 ybeC - - E - - - amino acid
LGCOMDED_04218 1.94e-136 yvdT_1 - - K - - - Transcriptional regulator
LGCOMDED_04219 4.27e-66 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
LGCOMDED_04220 2.44e-65 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
LGCOMDED_04221 7.83e-96 yvdQ - - S - - - Protein of unknown function (DUF3231)
LGCOMDED_04222 1.07e-78 - - - - - - - -
LGCOMDED_04223 7.35e-46 - - - S - - - Bacteriophage A118-like holin, Hol118
LGCOMDED_04224 2.42e-193 - 3.5.1.28 - MT ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
LGCOMDED_04225 3.73e-40 - - - S - - - Haemolysin XhlA
LGCOMDED_04228 4.8e-124 - - - - - - - -
LGCOMDED_04229 0.0 - - - S - - - Peptidase_G2, IMC autoproteolytic cleavage domain
LGCOMDED_04230 1.03e-237 - - - L - - - Prophage endopeptidase tail
LGCOMDED_04231 5.63e-138 - - - S - - - Phage tail protein
LGCOMDED_04232 9.4e-128 - - - D - - - Phage tail tape measure protein
LGCOMDED_04233 9.32e-43 - - - - - - - -
LGCOMDED_04234 1.57e-93 - - - N - - - phage major tail protein, phi13 family
LGCOMDED_04235 6.19e-24 - - - - - - - -
LGCOMDED_04237 6.14e-46 - - - S - - - Phage head-tail joining protein
LGCOMDED_04238 3.82e-34 - - - S - - - Phage gp6-like head-tail connector protein
LGCOMDED_04239 1.81e-50 - - - N - - - domain, Protein
LGCOMDED_04240 2.75e-217 - - - S - - - Phage capsid family
LGCOMDED_04241 3.3e-143 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
LGCOMDED_04242 9.54e-286 - - - S - - - Phage portal protein
LGCOMDED_04243 0.0 - - - S - - - Terminase
LGCOMDED_04244 8.45e-62 - - - L - - - Phage terminase, small subunit
LGCOMDED_04245 8.05e-42 - - - L ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
LGCOMDED_04247 3.75e-53 - - - - - - - -
LGCOMDED_04259 7.11e-05 - - - K - - - Psort location Cytoplasmic, score
LGCOMDED_04260 1.05e-129 - - - L - - - Phage integrase family
LGCOMDED_04262 8.37e-32 - - - - - - - -
LGCOMDED_04263 2.37e-137 - - - S - - - Helix-turn-helix domain
LGCOMDED_04264 2.19e-40 - - - L - - - Phage integrase family
LGCOMDED_04266 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LGCOMDED_04267 7.59e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
LGCOMDED_04268 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
LGCOMDED_04269 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
LGCOMDED_04270 5.63e-197 malA - - S - - - Protein of unknown function (DUF1189)
LGCOMDED_04271 6.56e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
LGCOMDED_04272 2.48e-310 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
LGCOMDED_04273 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
LGCOMDED_04274 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
LGCOMDED_04275 8.92e-221 yvdE - - K - - - Transcriptional regulator
LGCOMDED_04276 3.11e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
LGCOMDED_04277 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
LGCOMDED_04278 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
LGCOMDED_04279 5.3e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
LGCOMDED_04280 2.32e-234 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGCOMDED_04281 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LGCOMDED_04282 8.99e-29 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
LGCOMDED_04283 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
LGCOMDED_04284 1.96e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
LGCOMDED_04285 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LGCOMDED_04286 2.2e-42 - - - - - - - -
LGCOMDED_04287 8.02e-183 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
LGCOMDED_04288 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
LGCOMDED_04289 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
LGCOMDED_04290 5.52e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
LGCOMDED_04291 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
LGCOMDED_04292 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LGCOMDED_04293 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LGCOMDED_04294 4.38e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
LGCOMDED_04295 5.23e-153 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LGCOMDED_04296 8.96e-38 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LGCOMDED_04298 1.35e-44 - - - - - - - -
LGCOMDED_04300 2.5e-109 - - - E - - - phosphoribosylanthranilate isomerase activity
LGCOMDED_04301 1.28e-69 - - - S - - - Domain of unknown function (DUF3885)
LGCOMDED_04302 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
LGCOMDED_04303 1.46e-77 - - - S ko:K06518 - ko00000,ko02000 LrgA family
LGCOMDED_04304 4.06e-149 yxaC - - M - - - effector of murein hydrolase
LGCOMDED_04305 1.07e-84 - - - S - - - TIGRFAM germination protein, Ger(x)C family
LGCOMDED_04306 1.5e-125 - - - EG - - - Spore germination protein
LGCOMDED_04308 1.86e-135 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
LGCOMDED_04309 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
LGCOMDED_04310 2.31e-110 - - - L - - - Tn3 transposase DDE domain
LGCOMDED_04311 1.8e-99 - - - - - - - -
LGCOMDED_04312 1.59e-65 - - - L - - - Transposase
LGCOMDED_04313 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
LGCOMDED_04314 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LGCOMDED_04315 4.67e-95 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
LGCOMDED_04317 4.01e-127 yqjB - - S - - - protein conserved in bacteria
LGCOMDED_04318 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
LGCOMDED_04319 1.28e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
LGCOMDED_04320 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
LGCOMDED_04321 1.43e-175 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
LGCOMDED_04322 6.29e-100 yqiW - - S - - - Belongs to the UPF0403 family
LGCOMDED_04323 5.76e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LGCOMDED_04324 1.26e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
LGCOMDED_04325 9.06e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
LGCOMDED_04326 1.87e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LGCOMDED_04327 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LGCOMDED_04328 1.92e-238 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LGCOMDED_04329 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LGCOMDED_04330 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
LGCOMDED_04331 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
LGCOMDED_04332 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
LGCOMDED_04333 0.0 bkdR - - KT - - - Transcriptional regulator
LGCOMDED_04334 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
LGCOMDED_04335 4.18e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LGCOMDED_04336 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
LGCOMDED_04337 1.66e-267 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
LGCOMDED_04338 4.24e-269 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
LGCOMDED_04339 1.98e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
LGCOMDED_04340 1.91e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
LGCOMDED_04341 1.88e-165 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
LGCOMDED_04342 3.83e-137 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
LGCOMDED_04343 1.36e-36 - - - - - - - -
LGCOMDED_04345 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LGCOMDED_04347 3.14e-185 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LGCOMDED_04348 2.96e-302 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
LGCOMDED_04349 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
LGCOMDED_04350 4.38e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
LGCOMDED_04351 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
LGCOMDED_04352 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGCOMDED_04353 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
LGCOMDED_04354 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LGCOMDED_04355 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LGCOMDED_04356 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGCOMDED_04357 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGCOMDED_04358 9.55e-88 yqhY - - S - - - protein conserved in bacteria
LGCOMDED_04359 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LGCOMDED_04360 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LGCOMDED_04361 4.04e-134 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
LGCOMDED_04362 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
LGCOMDED_04363 2.58e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
LGCOMDED_04364 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
LGCOMDED_04365 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
LGCOMDED_04366 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
LGCOMDED_04367 5.69e-111 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
LGCOMDED_04368 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
LGCOMDED_04369 9.89e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
LGCOMDED_04370 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGCOMDED_04371 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
LGCOMDED_04372 1.94e-100 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
LGCOMDED_04373 3.27e-120 yqhR - - S - - - Conserved membrane protein YqhR
LGCOMDED_04374 4.95e-219 yqhQ - - S - - - Protein of unknown function (DUF1385)
LGCOMDED_04375 1.94e-75 yqhP - - - - - - -
LGCOMDED_04376 9.94e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
LGCOMDED_04377 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LGCOMDED_04378 2.63e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LGCOMDED_04379 2.51e-81 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
LGCOMDED_04380 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LGCOMDED_04381 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LGCOMDED_04382 1.91e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
LGCOMDED_04383 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
LGCOMDED_04384 9.14e-197 yqhG - - S - - - Bacterial protein YqhG of unknown function
LGCOMDED_04385 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
LGCOMDED_04386 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
LGCOMDED_04387 9e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
LGCOMDED_04388 1.74e-96 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
LGCOMDED_04389 3.33e-129 yqxM - - - ko:K19433 - ko00000 -
LGCOMDED_04390 3.68e-70 yqzG - - S - - - Protein of unknown function (DUF3889)
LGCOMDED_04391 2.84e-36 yqzE - - S - - - YqzE-like protein
LGCOMDED_04392 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
LGCOMDED_04393 1.17e-59 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
LGCOMDED_04394 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
LGCOMDED_04395 5.39e-91 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
LGCOMDED_04396 1.26e-61 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
LGCOMDED_04397 2.55e-211 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
LGCOMDED_04398 1.5e-255 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGCOMDED_04399 2.4e-230 yqxL - - P - - - Mg2 transporter protein
LGCOMDED_04400 1.65e-304 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
LGCOMDED_04401 2.29e-188 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LGCOMDED_04403 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
LGCOMDED_04404 1.41e-48 yqgY - - S - - - Protein of unknown function (DUF2626)
LGCOMDED_04405 3.07e-155 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
LGCOMDED_04406 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
LGCOMDED_04407 7.34e-66 yqgV - - S - - - Thiamine-binding protein
LGCOMDED_04408 7.7e-256 yqgU - - - - - - -
LGCOMDED_04409 5.04e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
LGCOMDED_04410 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
LGCOMDED_04411 1.62e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
LGCOMDED_04412 8.83e-43 yqgQ - - S - - - Protein conserved in bacteria
LGCOMDED_04413 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
LGCOMDED_04414 3.38e-14 yqgO - - - - - - -
LGCOMDED_04415 3.8e-135 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGCOMDED_04416 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
LGCOMDED_04417 1.56e-254 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
LGCOMDED_04419 2.81e-67 yqzD - - - - - - -
LGCOMDED_04420 1.09e-93 yqzC - - S - - - YceG-like family
LGCOMDED_04421 1.29e-185 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LGCOMDED_04422 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LGCOMDED_04423 2.14e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
LGCOMDED_04424 8.29e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
LGCOMDED_04425 7.59e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
LGCOMDED_04426 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
LGCOMDED_04427 1.54e-290 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
LGCOMDED_04428 1.31e-147 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
LGCOMDED_04429 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
LGCOMDED_04430 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
LGCOMDED_04431 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
LGCOMDED_04432 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LGCOMDED_04433 2.38e-80 yqfX - - S - - - membrane
LGCOMDED_04434 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
LGCOMDED_04435 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
LGCOMDED_04436 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
LGCOMDED_04437 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
LGCOMDED_04438 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGCOMDED_04439 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LGCOMDED_04440 1.56e-44 yqfQ - - S - - - YqfQ-like protein
LGCOMDED_04441 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGCOMDED_04442 7.55e-59 orfX1 - - L - - - Transposase
LGCOMDED_04443 2.01e-122 ytbE - - S - - - reductase
LGCOMDED_04444 3.21e-47 - - - EG - - - Spore germination protein

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)