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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HEMLNNMD_00001	3.34e-101	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HEMLNNMD_00002	2.8e-161	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HEMLNNMD_00003	1.93e-175	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HEMLNNMD_00004	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HEMLNNMD_00005	3.06e-222	ykvI	-	-	S	-	-	-	membrane
HEMLNNMD_00006	4.92e-233	-	-	-	-	-	-	-	-
HEMLNNMD_00007	2.72e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HEMLNNMD_00008	8.88e-103	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HEMLNNMD_00009	5.67e-176	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HEMLNNMD_00010	2.56e-124	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HEMLNNMD_00011	7.02e-58	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HEMLNNMD_00012	1.56e-34	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00013	2.92e-38	-	-	-	-	-	-	-	-
HEMLNNMD_00014	6.11e-135	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HEMLNNMD_00015	3.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEMLNNMD_00016	8.87e-107	stoA	-	-	CO	-	-	-	thiol-disulfide
HEMLNNMD_00017	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HEMLNNMD_00018	9.11e-261	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HEMLNNMD_00020	1.03e-217	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_00021	1.54e-196	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HEMLNNMD_00022	0.0	ptsG	2.7.1.199	-	G	ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_00023	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HEMLNNMD_00024	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEMLNNMD_00025	1.22e-48	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_00026	2.29e-252	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HEMLNNMD_00027	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEMLNNMD_00028	3.3e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HEMLNNMD_00029	3.34e-65	-	-	-	-	-	-	-	-
HEMLNNMD_00030	9.4e-165	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HEMLNNMD_00031	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEMLNNMD_00032	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_00033	9e-273	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEMLNNMD_00034	2.22e-15	-	-	-	-	-	-	-	-
HEMLNNMD_00035	1.3e-211	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HEMLNNMD_00036	1.45e-107	ykyB	-	-	S	-	-	-	YkyB-like protein
HEMLNNMD_00037	4.93e-303	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_00038	2.01e-113	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00039	4.21e-187	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HEMLNNMD_00040	2.29e-176	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_00042	1.74e-293	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HEMLNNMD_00043	2.11e-49	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00044	1.4e-116	ykuK	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HEMLNNMD_00045	2.63e-36	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HEMLNNMD_00046	8.55e-99	ykuL	-	-	S	-	-	-	CBS domain
HEMLNNMD_00047	1.08e-214	ccpC	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_00048	1.02e-113	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEMLNNMD_00049	8.78e-207	ykuO	-	-	-	-	-	-	-
HEMLNNMD_00050	2.33e-98	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HEMLNNMD_00051	4.79e-128	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEMLNNMD_00052	1.22e-270	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEMLNNMD_00053	1.25e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HEMLNNMD_00054	1.17e-176	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HEMLNNMD_00056	1.29e-91	ykuV	-	-	CO	-	-	-	thiol-disulfide
HEMLNNMD_00057	1.18e-28	rok	-	-	K	-	-	-	Repressor of ComK
HEMLNNMD_00058	2.44e-81	rok	-	-	K	-	-	-	Repressor of ComK
HEMLNNMD_00059	3.98e-199	yknT	-	-	-	ko:K06437	-	ko00000	-
HEMLNNMD_00060	1.34e-109	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEMLNNMD_00061	4.32e-235	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEMLNNMD_00062	1.72e-303	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HEMLNNMD_00063	7.51e-112	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HEMLNNMD_00064	7.17e-109	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HEMLNNMD_00065	1.58e-41	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HEMLNNMD_00067	3.04e-129	yknW	-	-	S	-	-	-	Yip1 domain
HEMLNNMD_00068	2.98e-225	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEMLNNMD_00069	1.96e-156	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_00070	2.73e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_00071	8.9e-168	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_00072	8.8e-210	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HEMLNNMD_00073	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HEMLNNMD_00074	3.77e-138	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEMLNNMD_00075	1.44e-47	ykoA	-	-	-	-	-	-	-
HEMLNNMD_00076	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEMLNNMD_00077	9.75e-202	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEMLNNMD_00078	9.45e-300	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HEMLNNMD_00079	7.7e-19	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HEMLNNMD_00080	1.06e-233	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HEMLNNMD_00081	7.46e-59	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HEMLNNMD_00082	7.52e-300	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEMLNNMD_00083	1.98e-192	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HEMLNNMD_00084	9.71e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HEMLNNMD_00085	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEMLNNMD_00086	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEMLNNMD_00087	7.4e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HEMLNNMD_00088	2.12e-178	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HEMLNNMD_00089	1.81e-127	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEMLNNMD_00090	4.93e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEMLNNMD_00091	1.64e-126	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HEMLNNMD_00092	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEMLNNMD_00093	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00094	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00095	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
HEMLNNMD_00096	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	polyketide synthase
HEMLNNMD_00097	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00098	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00099	4.53e-56	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00100	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00101	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00102	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00103	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00104	0.0	-	-	-	IQ	-	-	-	Phosphopantetheine attachment site
HEMLNNMD_00105	1.69e-19	-	-	-	V	-	-	-	Beta-lactamase
HEMLNNMD_00106	3.8e-199	-	-	-	V	-	-	-	Beta-lactamase
HEMLNNMD_00108	3.17e-260	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEMLNNMD_00109	2.38e-225	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEMLNNMD_00110	1.71e-300	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEMLNNMD_00111	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEMLNNMD_00112	6.84e-60	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HEMLNNMD_00113	6.72e-173	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HEMLNNMD_00114	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HEMLNNMD_00115	1.29e-54	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HEMLNNMD_00116	4.72e-154	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HEMLNNMD_00117	7.89e-32	ykzI	-	-	-	-	-	-	-
HEMLNNMD_00118	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HEMLNNMD_00119	2.25e-100	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HEMLNNMD_00120	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HEMLNNMD_00121	2.52e-220	ylaA	-	-	-	-	-	-	-
HEMLNNMD_00122	4.64e-53	ylaB	-	-	-	-	-	-	-
HEMLNNMD_00123	3.39e-112	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_00125	3.48e-45	ylaE	-	-	-	-	-	-	-
HEMLNNMD_00126	5.62e-33	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HEMLNNMD_00127	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HEMLNNMD_00128	4.22e-59	-	-	-	S	-	-	-	YlaH-like protein
HEMLNNMD_00129	7.97e-131	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEMLNNMD_00130	4.29e-310	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HEMLNNMD_00131	4.45e-104	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HEMLNNMD_00132	3.21e-215	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEMLNNMD_00133	1.99e-58	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HEMLNNMD_00134	1.52e-265	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEMLNNMD_00135	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HEMLNNMD_00136	3.88e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HEMLNNMD_00137	1.2e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEMLNNMD_00138	1.32e-249	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HEMLNNMD_00139	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEMLNNMD_00140	3.43e-141	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HEMLNNMD_00141	3.53e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HEMLNNMD_00142	3.17e-206	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HEMLNNMD_00143	1.96e-77	ylbA	-	-	S	-	-	-	YugN-like family
HEMLNNMD_00144	1.94e-95	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HEMLNNMD_00145	5.56e-246	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HEMLNNMD_00146	2.72e-83	ylbD	-	-	S	-	-	-	Putative coat protein
HEMLNNMD_00147	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HEMLNNMD_00148	3.73e-94	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HEMLNNMD_00149	4.62e-56	ylbG	-	-	S	-	-	-	UPF0298 protein
HEMLNNMD_00150	4.27e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HEMLNNMD_00151	2.38e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEMLNNMD_00152	4.19e-231	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HEMLNNMD_00153	2.03e-177	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HEMLNNMD_00154	4.48e-233	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HEMLNNMD_00155	3.15e-170	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HEMLNNMD_00156	7e-83	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HEMLNNMD_00157	4.69e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HEMLNNMD_00158	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HEMLNNMD_00159	1.93e-105	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HEMLNNMD_00160	6.58e-116	ylbP	-	-	K	-	-	-	n-acetyltransferase
HEMLNNMD_00161	8.05e-193	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEMLNNMD_00162	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HEMLNNMD_00163	9.07e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HEMLNNMD_00164	2.75e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEMLNNMD_00165	2.81e-67	ftsL	-	-	D	-	-	-	Essential cell division protein
HEMLNNMD_00166	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HEMLNNMD_00167	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HEMLNNMD_00168	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEMLNNMD_00169	2.36e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEMLNNMD_00170	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEMLNNMD_00171	2.7e-236	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEMLNNMD_00172	4.13e-227	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEMLNNMD_00173	2.63e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HEMLNNMD_00174	3.74e-170	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEMLNNMD_00175	3.7e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEMLNNMD_00176	4.32e-259	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEMLNNMD_00177	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HEMLNNMD_00178	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HEMLNNMD_00179	3.59e-212	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HEMLNNMD_00180	3.64e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_00181	3.8e-178	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_00182	1.82e-183	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HEMLNNMD_00183	2.03e-309	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HEMLNNMD_00184	7.13e-52	ylmC	-	-	S	-	-	-	sporulation protein
HEMLNNMD_00185	4.01e-198	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HEMLNNMD_00186	1.96e-156	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEMLNNMD_00187	8.91e-83	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEMLNNMD_00188	5.12e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HEMLNNMD_00189	1.14e-177	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HEMLNNMD_00190	1.85e-99	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HEMLNNMD_00191	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEMLNNMD_00192	4.22e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HEMLNNMD_00193	8.42e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEMLNNMD_00194	7.29e-214	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HEMLNNMD_00195	2.21e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEMLNNMD_00196	6.33e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HEMLNNMD_00197	4.84e-203	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HEMLNNMD_00198	4.1e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEMLNNMD_00199	4.04e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEMLNNMD_00200	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HEMLNNMD_00201	2.79e-178	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEMLNNMD_00202	1.59e-216	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEMLNNMD_00203	1.6e-157	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEMLNNMD_00204	1.05e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEMLNNMD_00206	3.87e-178	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HEMLNNMD_00207	1.06e-222	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HEMLNNMD_00208	1.98e-280	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HEMLNNMD_00209	3.61e-138	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HEMLNNMD_00210	1.05e-178	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HEMLNNMD_00211	1.56e-182	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HEMLNNMD_00212	1.85e-98	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HEMLNNMD_00213	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HEMLNNMD_00214	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HEMLNNMD_00215	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HEMLNNMD_00216	8e-194	yloC	-	-	S	-	-	-	stress-induced protein
HEMLNNMD_00217	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HEMLNNMD_00218	1.16e-142	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HEMLNNMD_00219	2.53e-38	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEMLNNMD_00220	2e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEMLNNMD_00221	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEMLNNMD_00222	8.3e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEMLNNMD_00223	2.84e-20	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEMLNNMD_00224	1.33e-175	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEMLNNMD_00225	8.37e-315	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEMLNNMD_00226	1.25e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEMLNNMD_00227	4.51e-165	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HEMLNNMD_00228	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEMLNNMD_00229	4.32e-202	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEMLNNMD_00230	2.06e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HEMLNNMD_00231	1.28e-144	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HEMLNNMD_00232	3.49e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HEMLNNMD_00233	1.05e-77	yloU	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00234	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HEMLNNMD_00235	2.8e-151	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HEMLNNMD_00236	1.02e-189	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HEMLNNMD_00237	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEMLNNMD_00238	2.96e-119	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HEMLNNMD_00239	1.28e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEMLNNMD_00240	3.09e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEMLNNMD_00241	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HEMLNNMD_00242	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEMLNNMD_00243	1.43e-172	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEMLNNMD_00244	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HEMLNNMD_00245	4.41e-223	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEMLNNMD_00246	2.63e-167	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HEMLNNMD_00247	1.97e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEMLNNMD_00248	2.09e-303	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEMLNNMD_00249	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HEMLNNMD_00250	1.16e-47	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HEMLNNMD_00251	8.03e-79	ylqD	-	-	S	-	-	-	YlqD protein
HEMLNNMD_00252	6.16e-121	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEMLNNMD_00253	1.34e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HEMLNNMD_00254	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEMLNNMD_00255	8.1e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEMLNNMD_00256	2.09e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEMLNNMD_00257	0.0	ylqG	-	-	-	-	-	-	-
HEMLNNMD_00258	6.94e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HEMLNNMD_00259	2.26e-267	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HEMLNNMD_00260	1.26e-212	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HEMLNNMD_00261	1.12e-210	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HEMLNNMD_00262	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEMLNNMD_00263	4.29e-311	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEMLNNMD_00264	4.75e-215	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HEMLNNMD_00265	4.99e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HEMLNNMD_00266	1.49e-309	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HEMLNNMD_00267	7.94e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HEMLNNMD_00268	7.71e-82	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HEMLNNMD_00269	2.42e-95	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HEMLNNMD_00270	4.34e-50	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HEMLNNMD_00271	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HEMLNNMD_00272	2.48e-229	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEMLNNMD_00273	1.04e-119	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HEMLNNMD_00274	1.43e-306	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HEMLNNMD_00275	7.27e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HEMLNNMD_00276	2.82e-78	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HEMLNNMD_00277	3.19e-234	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HEMLNNMD_00278	7.26e-92	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HEMLNNMD_00279	1.81e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HEMLNNMD_00280	1.49e-77	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HEMLNNMD_00281	6.33e-229	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HEMLNNMD_00282	2.2e-227	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HEMLNNMD_00283	2.12e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HEMLNNMD_00284	1.09e-142	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HEMLNNMD_00285	9.98e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HEMLNNMD_00286	9.02e-51	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HEMLNNMD_00287	1.29e-164	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HEMLNNMD_00288	2.22e-238	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEMLNNMD_00289	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HEMLNNMD_00290	4.8e-235	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HEMLNNMD_00291	2.37e-195	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HEMLNNMD_00292	1.4e-239	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HEMLNNMD_00293	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HEMLNNMD_00294	2.91e-104	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HEMLNNMD_00295	5.91e-143	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HEMLNNMD_00296	1.65e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HEMLNNMD_00297	3.96e-177	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_00298	3.33e-71	ylxL	-	-	-	-	-	-	-
HEMLNNMD_00299	4.77e-165	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HEMLNNMD_00300	2.21e-198	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEMLNNMD_00301	2.89e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HEMLNNMD_00302	5.55e-118	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEMLNNMD_00303	1.1e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEMLNNMD_00304	6.29e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HEMLNNMD_00305	6.04e-271	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEMLNNMD_00306	3.29e-280	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HEMLNNMD_00307	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEMLNNMD_00308	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEMLNNMD_00310	6.87e-159	-	-	-	S	-	-	-	Lantibiotic dehydratase, C terminus
HEMLNNMD_00311	2.28e-139	-	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC superfamily ATP binding cassette transporter, ABC
HEMLNNMD_00312	1.76e-65	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
HEMLNNMD_00313	7.64e-60	-	-	-	L	-	-	-	transposase activity
HEMLNNMD_00314	5.44e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HEMLNNMD_00315	1.11e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HEMLNNMD_00316	6.76e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HEMLNNMD_00317	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HEMLNNMD_00318	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEMLNNMD_00319	1.58e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HEMLNNMD_00320	1.03e-73	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEMLNNMD_00321	1.31e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEMLNNMD_00322	5.19e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HEMLNNMD_00323	4.12e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEMLNNMD_00324	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEMLNNMD_00325	2.3e-229	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HEMLNNMD_00326	8.05e-297	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HEMLNNMD_00327	2.17e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HEMLNNMD_00328	4.32e-202	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HEMLNNMD_00329	1.41e-130	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HEMLNNMD_00330	5.8e-248	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEMLNNMD_00331	5.48e-280	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEMLNNMD_00332	7.2e-202	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEMLNNMD_00333	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEMLNNMD_00334	3.38e-169	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HEMLNNMD_00335	3.02e-40	-	-	-	S	-	-	-	YlzJ-like protein
HEMLNNMD_00336	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEMLNNMD_00337	8.32e-168	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_00338	1.77e-284	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_00339	1.58e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_00340	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HEMLNNMD_00341	9.89e-301	albE	-	-	S	-	-	-	Peptidase M16
HEMLNNMD_00342	1.08e-305	ymfH	-	-	S	-	-	-	zinc protease
HEMLNNMD_00343	3.23e-161	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HEMLNNMD_00344	6.23e-56	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HEMLNNMD_00345	3.82e-184	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HEMLNNMD_00346	4.78e-168	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HEMLNNMD_00347	4.75e-132	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEMLNNMD_00348	2.3e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HEMLNNMD_00349	3.99e-235	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEMLNNMD_00350	5.47e-227	pbpX	-	-	V	-	-	-	Beta-lactamase
HEMLNNMD_00351	5.59e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HEMLNNMD_00352	7.51e-196	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HEMLNNMD_00353	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HEMLNNMD_00354	2.34e-241	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HEMLNNMD_00355	4.79e-272	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEMLNNMD_00356	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEMLNNMD_00357	2.46e-87	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HEMLNNMD_00358	4.1e-118	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HEMLNNMD_00359	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEMLNNMD_00360	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEMLNNMD_00362	1.77e-160	pksB	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	Polyketide biosynthesis
HEMLNNMD_00363	2.31e-198	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEMLNNMD_00364	5.43e-210	pksD	-	-	Q	ko:K15328	-	ko00000,ko01008	Acyl transferase domain
HEMLNNMD_00365	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEMLNNMD_00366	1.24e-47	acpK	-	-	IQ	ko:K15337	-	ko00000,ko01008	Phosphopantetheine attachment site
HEMLNNMD_00367	4.95e-307	pksG	2.3.3.10	-	I	ko:K01641,ko:K15311	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01008	synthase
HEMLNNMD_00368	4.28e-178	-	-	-	I	ko:K15312	-	ko00000,ko01008	enoyl-CoA hydratase
HEMLNNMD_00369	6.35e-176	pksI	-	-	I	ko:K15313	-	ko00000,ko01008	Belongs to the enoyl-CoA hydratase isomerase family
HEMLNNMD_00370	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEMLNNMD_00371	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEMLNNMD_00372	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00373	3.94e-105	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00374	0.0	-	-	-	Q	ko:K13612,ko:K13613	-	ko00000,ko01004,ko01008	Polyketide synthase of type I
HEMLNNMD_00375	0.0	-	-	-	IQ	ko:K13611,ko:K13614	-	ko00000,ko01004,ko01008	polyketide synthase
HEMLNNMD_00376	0.0	-	-	-	HQ	ko:K13615	-	ko00000,ko01004,ko01008	Beta-ketoacyl synthase
HEMLNNMD_00377	3.72e-282	cypA	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEMLNNMD_00378	1.74e-92	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEMLNNMD_00379	7.12e-44	yoaK	-	-	S	-	-	-	Membrane
HEMLNNMD_00380	1.59e-81	yoaK	-	-	S	-	-	-	Membrane
HEMLNNMD_00381	1.88e-80	ymzB	-	-	-	-	-	-	-
HEMLNNMD_00382	3.76e-316	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HEMLNNMD_00383	1.86e-07	-	-	-	-	-	-	-	-
HEMLNNMD_00384	3.75e-152	ymaC	-	-	S	-	-	-	Replication protein
HEMLNNMD_00385	2.16e-98	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HEMLNNMD_00386	1.76e-70	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEMLNNMD_00387	4.09e-63	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEMLNNMD_00389	1.51e-70	ymaF	-	-	S	-	-	-	YmaF family
HEMLNNMD_00390	3.06e-211	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEMLNNMD_00391	9e-46	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HEMLNNMD_00392	1.12e-54	-	-	-	-	-	-	-	-
HEMLNNMD_00393	9.42e-29	ymzA	-	-	-	-	-	-	-
HEMLNNMD_00394	4.43e-77	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HEMLNNMD_00395	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEMLNNMD_00396	5.94e-237	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEMLNNMD_00397	6.33e-132	ymaB	-	-	S	-	-	-	MutT family
HEMLNNMD_00398	9.5e-136	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEMLNNMD_00399	7.38e-225	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HEMLNNMD_00400	4.71e-277	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEMLNNMD_00401	1.87e-307	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HEMLNNMD_00402	6.73e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HEMLNNMD_00403	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HEMLNNMD_00404	2.32e-151	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HEMLNNMD_00405	1.79e-270	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEMLNNMD_00406	3.42e-313	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
HEMLNNMD_00407	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HEMLNNMD_00408	3.05e-263	xylR	-	-	GK	-	-	-	ROK family
HEMLNNMD_00409	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
HEMLNNMD_00410	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
HEMLNNMD_00411	1.09e-150	-	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HEMLNNMD_00412	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HEMLNNMD_00415	1.6e-155	yobV	-	-	K	-	-	-	WYL domain
HEMLNNMD_00416	2.77e-89	dinB	-	-	S	-	-	-	DinB family
HEMLNNMD_00417	1.67e-227	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HEMLNNMD_00419	6.69e-52	-	-	-	-	-	-	-	-
HEMLNNMD_00420	2.04e-10	-	-	-	-	-	-	-	-
HEMLNNMD_00421	8.3e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF4025)
HEMLNNMD_00422	1.69e-13	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HEMLNNMD_00423	3.47e-166	yoaP	-	-	K	-	-	-	YoaP-like
HEMLNNMD_00424	5.4e-118	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEMLNNMD_00426	7.66e-48	-	-	-	-	-	-	-	-
HEMLNNMD_00428	1.09e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HEMLNNMD_00429	1.15e-239	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_00430	7.85e-151	-	-	AA10,CBM73	S	ko:K03933	-	ko00000	Pfam:Chitin_bind_3
HEMLNNMD_00431	9.32e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEMLNNMD_00432	1.97e-119	yvgO	-	-	-	-	-	-	-
HEMLNNMD_00434	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HEMLNNMD_00435	1.73e-159	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
HEMLNNMD_00436	1.33e-43	-	-	-	S	-	-	-	TM2 domain
HEMLNNMD_00437	9.69e-99	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HEMLNNMD_00438	5.34e-164	yndL	-	-	S	-	-	-	Replication protein
HEMLNNMD_00439	4.12e-10	-	-	-	-	-	-	-	-
HEMLNNMD_00440	6.02e-183	-	-	-	O	-	-	-	COG0330 Membrane protease subunits, stomatin prohibitin homologs
HEMLNNMD_00441	7.14e-83	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HEMLNNMD_00444	7.8e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEMLNNMD_00445	5.61e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HEMLNNMD_00446	2.04e-142	yneB	-	-	L	-	-	-	resolvase
HEMLNNMD_00447	2.72e-42	ynzC	-	-	S	-	-	-	UPF0291 protein
HEMLNNMD_00448	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HEMLNNMD_00449	9.97e-103	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HEMLNNMD_00450	6.2e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HEMLNNMD_00451	8.06e-33	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HEMLNNMD_00452	2.52e-98	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HEMLNNMD_00453	4.11e-75	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HEMLNNMD_00454	7.59e-97	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HEMLNNMD_00455	4.28e-92	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HEMLNNMD_00456	4.56e-78	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HEMLNNMD_00457	1.97e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HEMLNNMD_00458	6.2e-22	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HEMLNNMD_00459	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HEMLNNMD_00460	4.36e-114	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEMLNNMD_00461	2.66e-09	-	-	-	S	-	-	-	Fur-regulated basic protein B
HEMLNNMD_00463	1e-43	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HEMLNNMD_00464	8.11e-95	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HEMLNNMD_00465	5.95e-65	yneQ	-	-	-	-	-	-	-
HEMLNNMD_00466	3.27e-58	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HEMLNNMD_00467	7.46e-120	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEMLNNMD_00468	1.41e-89	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HEMLNNMD_00469	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEMLNNMD_00470	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEMLNNMD_00471	2.21e-19	-	-	-	-	-	-	-	-
HEMLNNMD_00472	1.23e-61	ynfC	-	-	-	-	-	-	-
HEMLNNMD_00473	1.76e-316	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HEMLNNMD_00474	2.54e-174	yndG	-	-	S	-	-	-	DoxX-like family
HEMLNNMD_00475	1.04e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HEMLNNMD_00476	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HEMLNNMD_00477	2.03e-67	yvlA	-	-	S	-	-	-	Domain of unknown function (DUF4870)
HEMLNNMD_00478	3.32e-211	-	-	-	T	-	-	-	Histidine kinase
HEMLNNMD_00479	6.59e-67	-	-	-	T	-	-	-	Histidine kinase
HEMLNNMD_00480	1.84e-155	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEMLNNMD_00481	4.93e-304	-	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HEMLNNMD_00482	0.0	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HEMLNNMD_00483	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_00484	0.0	-	-	-	Q	ko:K15662,ko:K15663	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_00485	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_00486	0.0	nrsA	-	-	Q	ko:K15661	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_00487	1.1e-261	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEMLNNMD_00488	5.13e-156	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HEMLNNMD_00489	2.24e-136	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEMLNNMD_00490	1.63e-98	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEMLNNMD_00491	6.36e-21	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEMLNNMD_00492	1.08e-207	bioI	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEMLNNMD_00493	1.26e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HEMLNNMD_00494	6.05e-157	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HEMLNNMD_00495	3.63e-253	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HEMLNNMD_00496	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HEMLNNMD_00497	3.49e-172	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HEMLNNMD_00498	6.91e-87	yngA	-	-	S	-	-	-	membrane
HEMLNNMD_00499	5e-197	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEMLNNMD_00500	3.08e-134	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
HEMLNNMD_00501	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEMLNNMD_00502	5.13e-171	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HEMLNNMD_00503	9.17e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HEMLNNMD_00504	2.28e-40	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HEMLNNMD_00505	3.22e-304	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HEMLNNMD_00506	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEMLNNMD_00507	6.97e-264	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEMLNNMD_00508	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HEMLNNMD_00509	1.94e-27	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HEMLNNMD_00510	0.0	-	-	-	Q	ko:K15656,ko:K15668	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	D-alanine [D-alanyl carrier protein] ligase activity
HEMLNNMD_00511	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_00512	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HEMLNNMD_00513	2.48e-226	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HEMLNNMD_00514	7.94e-307	yoeA	-	-	V	-	-	-	MATE efflux family protein
HEMLNNMD_00515	3.39e-121	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HEMLNNMD_00516	1.57e-234	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HEMLNNMD_00517	1.57e-51	-	-	-	-	-	-	-	-
HEMLNNMD_00518	1.04e-43	-	-	-	N	-	-	-	Kelch motif
HEMLNNMD_00519	4.38e-22	-	-	-	L	-	-	-	phage terminase small subunit
HEMLNNMD_00520	1.37e-19	-	-	-	S	-	-	-	Phage terminase, small subunit
HEMLNNMD_00524	2.01e-09	-	-	-	L	-	-	-	Phage integrase family
HEMLNNMD_00525	2.62e-23	-	-	-	L	-	-	-	Phage integrase family
HEMLNNMD_00527	7.69e-123	-	-	-	L	-	-	-	Integrase
HEMLNNMD_00528	7.83e-46	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HEMLNNMD_00529	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HEMLNNMD_00530	1.1e-245	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	-transporter
HEMLNNMD_00531	1.91e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HEMLNNMD_00532	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEMLNNMD_00533	4.94e-188	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_00534	3.11e-224	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HEMLNNMD_00535	9.23e-59	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HEMLNNMD_00536	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HEMLNNMD_00537	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HEMLNNMD_00538	4.67e-202	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_00539	2.89e-252	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEMLNNMD_00540	1.73e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEMLNNMD_00541	6.69e-81	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HEMLNNMD_00542	4.03e-156	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_00543	3.4e-47	-	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEMLNNMD_00544	1.2e-147	yoxB	-	-	-	-	-	-	-
HEMLNNMD_00545	2.9e-262	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HEMLNNMD_00546	0.0	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HEMLNNMD_00547	2.4e-237	yoaD	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEMLNNMD_00548	0.0	yoaE	-	-	C	-	-	-	belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEMLNNMD_00549	5.17e-35	yoaF	-	-	-	-	-	-	-
HEMLNNMD_00551	8.67e-124	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_00552	9.19e-40	-	-	-	-	-	-	-	-
HEMLNNMD_00554	5.01e-69	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HEMLNNMD_00555	8.89e-156	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HEMLNNMD_00556	1.68e-109	yobS	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_00557	5.54e-156	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEMLNNMD_00558	7.49e-117	yobW	-	-	-	-	-	-	-
HEMLNNMD_00559	4.46e-72	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HEMLNNMD_00560	1.34e-154	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEMLNNMD_00561	5.42e-117	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HEMLNNMD_00562	3.47e-172	-	-	-	J	-	-	-	Protein required for attachment to host cells
HEMLNNMD_00563	3.63e-120	yocC	-	-	-	-	-	-	-
HEMLNNMD_00564	2.94e-235	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HEMLNNMD_00566	6.61e-157	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HEMLNNMD_00567	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEMLNNMD_00569	2.32e-144	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEMLNNMD_00570	6.39e-79	yocK	-	-	T	-	-	-	general stress protein
HEMLNNMD_00572	1.65e-11	yocN	-	-	-	-	-	-	-
HEMLNNMD_00573	2.21e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEMLNNMD_00574	1.13e-58	yozN	-	-	-	-	-	-	-
HEMLNNMD_00575	1.83e-49	yocN	-	-	-	-	-	-	-
HEMLNNMD_00576	5.32e-75	yozO	-	-	S	-	-	-	Bacterial PH domain
HEMLNNMD_00578	4.69e-43	yozC	-	-	-	-	-	-	-
HEMLNNMD_00579	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEMLNNMD_00580	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HEMLNNMD_00581	5.12e-207	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HEMLNNMD_00582	7.69e-294	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEMLNNMD_00583	7.41e-210	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HEMLNNMD_00584	1.37e-165	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HEMLNNMD_00585	1.85e-256	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HEMLNNMD_00586	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HEMLNNMD_00587	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HEMLNNMD_00588	9.9e-208	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HEMLNNMD_00589	2.17e-134	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HEMLNNMD_00590	4.81e-276	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEMLNNMD_00591	4.85e-278	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HEMLNNMD_00592	3.97e-136	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEMLNNMD_00594	5.03e-296	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HEMLNNMD_00595	7.28e-186	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEMLNNMD_00596	2.61e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HEMLNNMD_00597	4.69e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HEMLNNMD_00598	3.66e-31	-	-	-	-	-	-	-	-
HEMLNNMD_00599	2.39e-200	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HEMLNNMD_00600	1.16e-100	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HEMLNNMD_00602	9.37e-83	iolK	-	-	S	-	-	-	tautomerase
HEMLNNMD_00603	2.25e-68	yodB	-	-	K	-	-	-	transcriptional
HEMLNNMD_00604	3.7e-136	yodC	-	-	C	-	-	-	nitroreductase
HEMLNNMD_00605	4.7e-138	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HEMLNNMD_00606	3.74e-213	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEMLNNMD_00607	1.14e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HEMLNNMD_00608	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEMLNNMD_00609	0.0	-	3.2.1.45	GH30	M	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 beta sandwich domain
HEMLNNMD_00610	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEMLNNMD_00611	3.79e-164	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_00612	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEMLNNMD_00613	3.36e-154	yodH	-	-	Q	-	-	-	Methyltransferase
HEMLNNMD_00614	7.46e-36	yodI	-	-	-	-	-	-	-
HEMLNNMD_00615	1.5e-190	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HEMLNNMD_00616	4.29e-161	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HEMLNNMD_00618	1.93e-60	yodL	-	-	S	-	-	-	YodL-like
HEMLNNMD_00619	1.39e-129	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HEMLNNMD_00620	1.97e-33	yozD	-	-	S	-	-	-	YozD-like protein
HEMLNNMD_00622	1.18e-155	yodN	-	-	-	-	-	-	-
HEMLNNMD_00623	6.19e-67	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEMLNNMD_00624	2.87e-47	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HEMLNNMD_00625	6.45e-59	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HEMLNNMD_00626	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HEMLNNMD_00627	1.61e-178	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HEMLNNMD_00628	9.6e-316	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HEMLNNMD_00629	1.74e-155	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HEMLNNMD_00630	1.49e-155	atoD	2.8.3.8, 2.8.3.9	-	I	ko:K01034	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HEMLNNMD_00631	7.34e-251	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEMLNNMD_00632	4.74e-09	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEMLNNMD_00634	2.78e-80	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
HEMLNNMD_00636	9.32e-175	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HEMLNNMD_00637	4.12e-289	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HEMLNNMD_00638	8.16e-54	cgeC	-	-	-	ko:K06321	-	ko00000	-
HEMLNNMD_00639	9.24e-83	cgeA	-	-	-	ko:K06319	-	ko00000	-
HEMLNNMD_00640	2.62e-214	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HEMLNNMD_00641	1e-269	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HEMLNNMD_00642	5.78e-91	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEMLNNMD_00645	2.09e-151	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	FMN-dependent dehydrogenase
HEMLNNMD_00647	6.05e-22	-	-	-	S	-	-	-	Regulatory protein YrvL
HEMLNNMD_00648	1.94e-262	yokA	-	-	L	-	-	-	Recombinase
HEMLNNMD_00649	3.03e-128	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEMLNNMD_00650	2.47e-101	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HEMLNNMD_00651	9.8e-115	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEMLNNMD_00652	3.91e-88	ypoP	-	-	K	-	-	-	transcriptional
HEMLNNMD_00653	2.55e-122	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00654	1.04e-166	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEMLNNMD_00655	2.24e-131	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HEMLNNMD_00656	3.66e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HEMLNNMD_00657	9.19e-304	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEMLNNMD_00658	2.28e-209	yplP	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_00659	7.14e-141	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HEMLNNMD_00660	3.29e-139	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEMLNNMD_00661	3.8e-111	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEMLNNMD_00662	3.6e-203	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEMLNNMD_00663	4.91e-143	ypjP	-	-	S	-	-	-	YpjP-like protein
HEMLNNMD_00664	4.56e-168	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HEMLNNMD_00665	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HEMLNNMD_00666	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HEMLNNMD_00667	2.44e-198	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HEMLNNMD_00668	8.73e-117	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HEMLNNMD_00669	5.15e-109	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HEMLNNMD_00671	1.28e-224	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEMLNNMD_00672	2.37e-271	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HEMLNNMD_00673	5.12e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HEMLNNMD_00674	4.27e-16	degR	-	-	-	-	-	-	-
HEMLNNMD_00675	5.37e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HEMLNNMD_00676	6.37e-38	ypeQ	-	-	S	-	-	-	Zinc-finger
HEMLNNMD_00677	7.41e-153	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HEMLNNMD_00678	3.96e-154	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HEMLNNMD_00679	2.03e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HEMLNNMD_00681	2.07e-204	ypcP	-	-	L	-	-	-	5'3' exonuclease
HEMLNNMD_00682	2.44e-10	-	-	-	-	-	-	-	-
HEMLNNMD_00683	3e-45	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HEMLNNMD_00684	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HEMLNNMD_00685	3.19e-111	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HEMLNNMD_00686	3.27e-255	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HEMLNNMD_00687	2.82e-133	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEMLNNMD_00688	3.4e-61	MGMT	-	-	L	ko:K07443	-	ko00000	6-O-methylguanine DNA methyltransferase, DNA binding domain
HEMLNNMD_00689	3.44e-08	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEMLNNMD_00690	1.26e-06	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEMLNNMD_00691	2.3e-294	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine
HEMLNNMD_00692	4.16e-122	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEMLNNMD_00693	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HEMLNNMD_00694	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HEMLNNMD_00696	6.91e-31	-	-	-	S	-	-	-	YpzG-like protein
HEMLNNMD_00697	1.71e-270	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HEMLNNMD_00698	5.52e-61	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEMLNNMD_00699	3.67e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HEMLNNMD_00700	8.12e-36	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
HEMLNNMD_00702	8.19e-286	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HEMLNNMD_00703	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HEMLNNMD_00704	2.85e-114	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HEMLNNMD_00705	1.7e-82	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEMLNNMD_00706	1.88e-69	yppG	-	-	S	-	-	-	YppG-like protein
HEMLNNMD_00710	0.00077	-	-	-	-	ko:K06430	-	ko00000	-
HEMLNNMD_00711	4.29e-225	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HEMLNNMD_00712	8.49e-144	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEMLNNMD_00713	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEMLNNMD_00714	2.66e-112	ypoC	-	-	-	-	-	-	-
HEMLNNMD_00715	1.4e-155	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEMLNNMD_00716	8.05e-166	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HEMLNNMD_00717	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HEMLNNMD_00718	1.91e-279	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEMLNNMD_00719	1.36e-95	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00720	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HEMLNNMD_00721	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HEMLNNMD_00722	1.63e-82	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HEMLNNMD_00723	4.82e-194	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HEMLNNMD_00724	2.31e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HEMLNNMD_00725	1.43e-226	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEMLNNMD_00726	9.21e-268	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEMLNNMD_00727	7.01e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HEMLNNMD_00728	3.8e-162	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HEMLNNMD_00729	9.56e-83	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HEMLNNMD_00730	9.38e-187	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEMLNNMD_00731	2.47e-74	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HEMLNNMD_00732	8.34e-197	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEMLNNMD_00733	4.08e-277	-	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HEMLNNMD_00734	7.66e-178	ypjB	-	-	S	-	-	-	sporulation protein
HEMLNNMD_00735	4.31e-126	ypjA	-	-	S	-	-	-	membrane
HEMLNNMD_00736	9.48e-190	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HEMLNNMD_00737	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HEMLNNMD_00738	2.27e-124	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HEMLNNMD_00739	2.97e-95	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HEMLNNMD_00740	7.45e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HEMLNNMD_00741	3.12e-291	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEMLNNMD_00742	9.3e-291	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEMLNNMD_00743	5.43e-255	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HEMLNNMD_00744	2.67e-251	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEMLNNMD_00745	1.08e-175	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HEMLNNMD_00746	3.74e-285	trpB	4.2.1.20	-	E	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HEMLNNMD_00747	2.99e-140	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HEMLNNMD_00748	1.99e-159	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HEMLNNMD_00749	1.09e-200	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HEMLNNMD_00750	5.41e-115	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEMLNNMD_00751	1.27e-220	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEMLNNMD_00752	4.68e-76	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HEMLNNMD_00753	1.88e-252	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEMLNNMD_00754	9.34e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEMLNNMD_00755	3.26e-177	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HEMLNNMD_00756	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HEMLNNMD_00757	6.56e-251	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEMLNNMD_00758	2.6e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEMLNNMD_00759	2.68e-175	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HEMLNNMD_00760	7.29e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HEMLNNMD_00761	6.27e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HEMLNNMD_00762	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEMLNNMD_00763	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEMLNNMD_00765	1.66e-101	yphF	-	-	-	-	-	-	-
HEMLNNMD_00766	1.13e-23	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HEMLNNMD_00767	6.44e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HEMLNNMD_00768	2.86e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HEMLNNMD_00769	6.38e-129	yphA	-	-	-	-	-	-	-
HEMLNNMD_00770	1.87e-12	-	-	-	S	-	-	-	YpzI-like protein
HEMLNNMD_00771	2.88e-229	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEMLNNMD_00772	3.17e-261	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HEMLNNMD_00773	6.49e-143	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HEMLNNMD_00774	1.12e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HEMLNNMD_00775	1.15e-72	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HEMLNNMD_00776	4.47e-311	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HEMLNNMD_00777	2.15e-203	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HEMLNNMD_00778	1.84e-155	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HEMLNNMD_00779	4e-234	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HEMLNNMD_00780	7.37e-311	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEMLNNMD_00781	7.9e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEMLNNMD_00782	5.62e-181	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HEMLNNMD_00783	3.73e-109	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HEMLNNMD_00784	1.78e-109	ypbE	-	-	M	-	-	-	Lysin motif
HEMLNNMD_00785	1.57e-124	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HEMLNNMD_00786	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEMLNNMD_00787	1.35e-240	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HEMLNNMD_00788	5.88e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HEMLNNMD_00789	3.59e-121	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEMLNNMD_00790	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEMLNNMD_00791	1.71e-218	rsiX	-	-	-	-	-	-	-
HEMLNNMD_00792	8.86e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_00793	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_00794	9.77e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_00795	3.09e-252	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HEMLNNMD_00796	5.7e-248	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HEMLNNMD_00797	7.12e-125	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HEMLNNMD_00798	1.45e-126	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEMLNNMD_00799	1.74e-166	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEMLNNMD_00800	7.39e-115	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HEMLNNMD_00801	2.08e-132	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HEMLNNMD_00802	1.36e-267	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEMLNNMD_00803	2.3e-104	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HEMLNNMD_00804	1.3e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEMLNNMD_00805	3.47e-165	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEMLNNMD_00807	1.35e-110	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HEMLNNMD_00808	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEMLNNMD_00809	8.08e-105	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HEMLNNMD_00810	4.07e-288	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEMLNNMD_00811	2.57e-140	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HEMLNNMD_00812	1.24e-257	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HEMLNNMD_00813	7.86e-68	ypuD	-	-	-	-	-	-	-
HEMLNNMD_00814	2.37e-124	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEMLNNMD_00815	6.23e-102	ccdC1	-	-	O	-	-	-	Protein of unknown function (DUF1453)
HEMLNNMD_00816	1.18e-103	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEMLNNMD_00817	1.17e-194	ypuA	-	-	S	-	-	-	Secreted protein
HEMLNNMD_00818	2.84e-316	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEMLNNMD_00819	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HEMLNNMD_00820	2.95e-139	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEMLNNMD_00821	3.57e-74	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HEMLNNMD_00822	9.17e-241	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HEMLNNMD_00823	2.85e-103	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HEMLNNMD_00824	7.71e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HEMLNNMD_00825	9.1e-141	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HEMLNNMD_00826	6.81e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_00827	4.77e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEMLNNMD_00828	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HEMLNNMD_00829	6.51e-269	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEMLNNMD_00830	2.05e-188	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEMLNNMD_00831	1.31e-289	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEMLNNMD_00832	4.38e-211	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HEMLNNMD_00833	5.51e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HEMLNNMD_00834	3.08e-102	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HEMLNNMD_00835	7.12e-142	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HEMLNNMD_00836	1.97e-07	yqkK	-	-	-	-	-	-	-
HEMLNNMD_00837	5.05e-33	-	-	-	-	-	-	-	-
HEMLNNMD_00838	3.1e-305	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HEMLNNMD_00839	7.17e-313	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HEMLNNMD_00840	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HEMLNNMD_00841	4.88e-236	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HEMLNNMD_00842	2.32e-75	ansR	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_00843	2.47e-272	yqxK	-	-	L	-	-	-	DNA helicase
HEMLNNMD_00844	1.42e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HEMLNNMD_00845	2.01e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HEMLNNMD_00846	5.74e-212	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HEMLNNMD_00847	3.06e-15	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HEMLNNMD_00848	4.33e-212	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEMLNNMD_00849	7.88e-54	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HEMLNNMD_00850	1.74e-76	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HEMLNNMD_00851	6.36e-166	yqkA	-	-	K	-	-	-	GrpB protein
HEMLNNMD_00852	1.08e-37	yqkA	-	-	K	-	-	-	GrpB protein
HEMLNNMD_00853	8.53e-69	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HEMLNNMD_00854	6.1e-295	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEMLNNMD_00855	3.08e-74	-	-	-	S	-	-	-	YolD-like protein
HEMLNNMD_00857	5.73e-206	yueF	-	-	S	-	-	-	transporter activity
HEMLNNMD_00859	3.01e-225	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HEMLNNMD_00860	5.94e-300	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HEMLNNMD_00861	8.58e-174	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_00862	2.24e-213	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEMLNNMD_00863	2.17e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEMLNNMD_00864	0.0	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HEMLNNMD_00865	5.05e-121	nusG1	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEMLNNMD_00866	1.96e-145	-	-	-	K	-	-	-	LysR substrate binding domain
HEMLNNMD_00867	2.42e-61	-	-	-	S	-	-	-	GlpM protein
HEMLNNMD_00868	1.04e-246	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HEMLNNMD_00869	8.38e-185	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HEMLNNMD_00870	4.44e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEMLNNMD_00871	8.52e-215	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEMLNNMD_00872	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEMLNNMD_00873	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEMLNNMD_00874	5.48e-294	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HEMLNNMD_00875	1.36e-36	yqzJ	-	-	-	-	-	-	-
HEMLNNMD_00876	6.56e-188	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEMLNNMD_00877	5.04e-257	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HEMLNNMD_00878	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HEMLNNMD_00879	5.21e-93	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HEMLNNMD_00881	6.62e-117	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00882	6.23e-217	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HEMLNNMD_00883	2.77e-161	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEMLNNMD_00884	6.03e-141	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEMLNNMD_00885	3.77e-171	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEMLNNMD_00886	1.68e-99	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HEMLNNMD_00887	1.19e-161	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEMLNNMD_00888	1.56e-264	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEMLNNMD_00889	1.15e-233	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEMLNNMD_00890	4.18e-217	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEMLNNMD_00891	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEMLNNMD_00892	1.11e-259	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HEMLNNMD_00893	6.15e-259	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEMLNNMD_00894	6.51e-193	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HEMLNNMD_00895	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HEMLNNMD_00896	7.32e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HEMLNNMD_00897	2.12e-200	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HEMLNNMD_00898	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HEMLNNMD_00899	1.63e-259	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEMLNNMD_00900	9.44e-109	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HEMLNNMD_00901	1.18e-126	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HEMLNNMD_00902	9.24e-186	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HEMLNNMD_00903	8.51e-267	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEMLNNMD_00904	2.98e-163	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEMLNNMD_00905	1.86e-125	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HEMLNNMD_00907	2.41e-117	-	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEMLNNMD_00908	3.85e-144	-	-	-	K	-	-	-	Protein of unknown function (DUF1232)
HEMLNNMD_00910	4.72e-265	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HEMLNNMD_00913	3.04e-260	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEMLNNMD_00915	2.05e-185	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEMLNNMD_00916	1.35e-298	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HEMLNNMD_00917	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HEMLNNMD_00918	1.03e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HEMLNNMD_00919	2.69e-193	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HEMLNNMD_00920	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEMLNNMD_00921	4.32e-202	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HEMLNNMD_00922	4.44e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEMLNNMD_00923	4.6e-74	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEMLNNMD_00924	1.35e-200	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEMLNNMD_00925	2.51e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEMLNNMD_00926	2.58e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEMLNNMD_00927	2.25e-86	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_00928	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HEMLNNMD_00929	2.59e-83	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEMLNNMD_00930	1.88e-86	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HEMLNNMD_00931	1.3e-145	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HEMLNNMD_00932	1.22e-66	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HEMLNNMD_00933	1.79e-43	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HEMLNNMD_00934	1.05e-260	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HEMLNNMD_00935	5.28e-55	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HEMLNNMD_00936	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HEMLNNMD_00937	2.71e-109	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HEMLNNMD_00938	2.26e-214	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HEMLNNMD_00939	1.16e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HEMLNNMD_00940	9.69e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEMLNNMD_00941	2.75e-245	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HEMLNNMD_00942	3.02e-113	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HEMLNNMD_00943	3.89e-216	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HEMLNNMD_00944	8.59e-80	yqhP	-	-	-	-	-	-	-
HEMLNNMD_00945	1.25e-203	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HEMLNNMD_00946	5.64e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HEMLNNMD_00947	1.78e-201	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HEMLNNMD_00948	1.35e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HEMLNNMD_00949	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEMLNNMD_00950	5.87e-311	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HEMLNNMD_00951	1.05e-251	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HEMLNNMD_00952	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEMLNNMD_00953	1.02e-193	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HEMLNNMD_00954	1.3e-29	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HEMLNNMD_00955	2.27e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HEMLNNMD_00956	8.28e-178	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HEMLNNMD_00957	1.91e-95	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HEMLNNMD_00958	7.32e-144	yqxM	-	-	-	ko:K19433	-	ko00000	-
HEMLNNMD_00959	3.28e-69	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HEMLNNMD_00960	1.65e-35	yqzE	-	-	S	-	-	-	YqzE-like protein
HEMLNNMD_00961	7.78e-71	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HEMLNNMD_00962	1e-63	comGF	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HEMLNNMD_00963	3.85e-27	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HEMLNNMD_00964	4.41e-91	-	-	-	NU	ko:K02246,ko:K08084	-	ko00000,ko00002,ko02044	Tfp pilus assembly protein FimT
HEMLNNMD_00965	8.07e-54	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HEMLNNMD_00966	6.75e-226	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HEMLNNMD_00967	6.83e-252	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HEMLNNMD_00968	1.1e-230	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HEMLNNMD_00969	1.1e-296	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEMLNNMD_00970	7.51e-177	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEMLNNMD_00972	2.15e-82	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HEMLNNMD_00973	4.19e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HEMLNNMD_00974	2e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HEMLNNMD_00975	1.07e-28	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HEMLNNMD_00976	3.5e-64	dglA	-	-	S	-	-	-	Thiamine-binding protein
HEMLNNMD_00977	1.34e-240	yqgU	-	-	-	-	-	-	-
HEMLNNMD_00978	2.3e-257	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HEMLNNMD_00979	1.18e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HEMLNNMD_00980	1.87e-37	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HEMLNNMD_00981	3.67e-269	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HEMLNNMD_00982	5.38e-11	yqgO	-	-	-	-	-	-	-
HEMLNNMD_00983	8.53e-117	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEMLNNMD_00984	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HEMLNNMD_00985	3.42e-68	yqzD	-	-	-	-	-	-	-
HEMLNNMD_00986	1.97e-96	yqzC	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEMLNNMD_00987	2.71e-187	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEMLNNMD_00988	8.56e-179	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEMLNNMD_00989	4.62e-196	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HEMLNNMD_00990	1.75e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HEMLNNMD_00991	1.06e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HEMLNNMD_00992	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HEMLNNMD_00993	5.94e-283	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HEMLNNMD_00994	4.22e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HEMLNNMD_00995	7.59e-97	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HEMLNNMD_00996	8.5e-165	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HEMLNNMD_00997	5.95e-59	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HEMLNNMD_00998	2.3e-255	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEMLNNMD_00999	3.9e-79	yqfX	-	-	S	-	-	-	membrane
HEMLNNMD_01000	3.23e-139	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HEMLNNMD_01001	2.63e-99	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HEMLNNMD_01002	2.47e-195	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEMLNNMD_01003	8.63e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HEMLNNMD_01004	1.85e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HEMLNNMD_01005	1.22e-307	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEMLNNMD_01006	7.12e-57	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HEMLNNMD_01007	4.12e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEMLNNMD_01008	4.21e-266	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEMLNNMD_01009	8.17e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HEMLNNMD_01010	7.67e-80	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HEMLNNMD_01011	8e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEMLNNMD_01012	9.49e-74	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEMLNNMD_01013	3.45e-316	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEMLNNMD_01014	2.09e-91	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HEMLNNMD_01015	1.75e-188	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HEMLNNMD_01016	3.41e-144	ccpN	-	-	K	-	-	-	CBS domain
HEMLNNMD_01017	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HEMLNNMD_01018	2.47e-221	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HEMLNNMD_01019	3.28e-181	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HEMLNNMD_01020	6e-24	-	-	-	S	-	-	-	YqzL-like protein
HEMLNNMD_01021	2.01e-214	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEMLNNMD_01022	2.73e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEMLNNMD_01023	7.21e-81	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HEMLNNMD_01024	2.91e-104	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEMLNNMD_01025	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HEMLNNMD_01026	2.37e-222	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HEMLNNMD_01027	1.68e-274	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HEMLNNMD_01028	3.57e-61	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HEMLNNMD_01029	1.28e-48	yqfB	-	-	-	-	-	-	-
HEMLNNMD_01030	1.22e-186	yqfA	-	-	S	-	-	-	UPF0365 protein
HEMLNNMD_01031	3.32e-285	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HEMLNNMD_01032	7.84e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HEMLNNMD_01033	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HEMLNNMD_01034	2.83e-194	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HEMLNNMD_01035	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HEMLNNMD_01036	3.96e-178	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEMLNNMD_01037	2.11e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HEMLNNMD_01038	4.72e-264	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEMLNNMD_01039	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HEMLNNMD_01040	1.4e-104	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEMLNNMD_01041	5.28e-238	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEMLNNMD_01042	1.65e-266	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HEMLNNMD_01043	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEMLNNMD_01044	2.88e-69	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HEMLNNMD_01045	4.32e-278	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HEMLNNMD_01046	4.65e-256	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEMLNNMD_01047	1.91e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HEMLNNMD_01048	2.37e-228	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HEMLNNMD_01049	7.73e-22	-	-	-	S	-	-	-	YqzM-like protein
HEMLNNMD_01050	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HEMLNNMD_01051	2.11e-133	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HEMLNNMD_01052	2.18e-122	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HEMLNNMD_01053	2.47e-185	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEMLNNMD_01054	7.42e-173	yqeM	-	-	Q	-	-	-	Methyltransferase
HEMLNNMD_01055	3.83e-79	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEMLNNMD_01056	7.98e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HEMLNNMD_01057	2.56e-134	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEMLNNMD_01058	8.62e-59	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HEMLNNMD_01059	5.24e-195	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEMLNNMD_01060	1.08e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HEMLNNMD_01061	7.28e-122	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HEMLNNMD_01063	3.83e-174	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HEMLNNMD_01064	3.4e-173	pdaC	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HEMLNNMD_01065	1.27e-139	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEMLNNMD_01066	9.76e-137	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HEMLNNMD_01067	1.85e-257	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HEMLNNMD_01068	1.17e-158	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_01069	1.52e-203	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HEMLNNMD_01070	9.07e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEMLNNMD_01071	1.29e-126	yqaC	-	-	F	-	-	-	adenylate kinase activity
HEMLNNMD_01072	2.77e-282	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_01073	3.48e-114	-	-	-	S	-	-	-	DinB family
HEMLNNMD_01074	1.6e-178	supH	-	-	S	-	-	-	hydrolase
HEMLNNMD_01075	9.98e-179	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HEMLNNMD_01076	9.18e-156	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HEMLNNMD_01077	4.38e-216	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEMLNNMD_01078	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_01079	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HEMLNNMD_01080	1.66e-215	romA	-	-	S	-	-	-	Beta-lactamase superfamily domain
HEMLNNMD_01081	5.57e-99	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEMLNNMD_01082	3.47e-206	yybE	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01083	1.29e-263	yybF1	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_01084	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HEMLNNMD_01085	3.6e-125	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HEMLNNMD_01086	8.92e-112	yrhH	-	-	Q	-	-	-	methyltransferase
HEMLNNMD_01087	8.27e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HEMLNNMD_01088	2.1e-178	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HEMLNNMD_01089	1.54e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HEMLNNMD_01090	0.0	yrhE	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEMLNNMD_01091	4.38e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEMLNNMD_01092	9.51e-47	yrhC	-	-	S	-	-	-	YrhC-like protein
HEMLNNMD_01093	2.65e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEMLNNMD_01094	8.52e-212	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HEMLNNMD_01095	5.64e-161	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEMLNNMD_01096	3.7e-148	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HEMLNNMD_01097	2.53e-38	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HEMLNNMD_01098	6.53e-120	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HEMLNNMD_01099	6.25e-210	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HEMLNNMD_01100	1.26e-175	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HEMLNNMD_01101	5.41e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEMLNNMD_01102	2.61e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HEMLNNMD_01103	1.8e-310	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HEMLNNMD_01104	1.22e-219	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HEMLNNMD_01105	5.63e-145	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HEMLNNMD_01106	1.71e-244	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEMLNNMD_01107	7.2e-61	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HEMLNNMD_01108	4.51e-92	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEMLNNMD_01109	1.29e-54	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HEMLNNMD_01110	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEMLNNMD_01111	4.87e-223	yrrI	-	-	S	-	-	-	AI-2E family transporter
HEMLNNMD_01112	1.43e-164	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEMLNNMD_01113	2.76e-183	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEMLNNMD_01114	1.13e-139	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEMLNNMD_01115	4.21e-136	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEMLNNMD_01116	6.52e-13	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HEMLNNMD_01117	8.4e-42	yrzR	-	-	-	-	-	-	-
HEMLNNMD_01118	7.39e-100	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_01119	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEMLNNMD_01120	1.12e-23	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEMLNNMD_01121	1.39e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEMLNNMD_01122	1.12e-264	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEMLNNMD_01123	3.74e-83	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_01124	2.07e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HEMLNNMD_01125	6.85e-178	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEMLNNMD_01126	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HEMLNNMD_01127	2.64e-304	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HEMLNNMD_01130	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HEMLNNMD_01131	4.75e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEMLNNMD_01132	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEMLNNMD_01133	1.71e-116	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEMLNNMD_01134	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HEMLNNMD_01135	1.24e-59	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HEMLNNMD_01136	3.2e-105	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HEMLNNMD_01137	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEMLNNMD_01138	2.26e-64	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HEMLNNMD_01139	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEMLNNMD_01140	1.16e-133	yrbG	-	-	S	-	-	-	membrane
HEMLNNMD_01141	7.46e-80	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HEMLNNMD_01142	1.03e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HEMLNNMD_01143	6.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEMLNNMD_01144	2.26e-243	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEMLNNMD_01145	2.39e-29	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HEMLNNMD_01146	8.05e-233	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEMLNNMD_01147	8.13e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEMLNNMD_01148	1.16e-118	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HEMLNNMD_01150	1.26e-60	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEMLNNMD_01151	1.25e-218	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HEMLNNMD_01152	1.71e-262	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HEMLNNMD_01153	6.44e-181	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HEMLNNMD_01154	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HEMLNNMD_01155	1.36e-267	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEMLNNMD_01156	1.05e-115	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HEMLNNMD_01157	1.51e-201	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HEMLNNMD_01158	5.94e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HEMLNNMD_01159	1.95e-308	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEMLNNMD_01160	8.24e-137	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HEMLNNMD_01161	7.74e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HEMLNNMD_01162	5.56e-72	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HEMLNNMD_01163	1.28e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HEMLNNMD_01164	1.29e-199	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HEMLNNMD_01165	4.21e-73	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEMLNNMD_01166	1.13e-84	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEMLNNMD_01167	1.61e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HEMLNNMD_01168	1.61e-153	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HEMLNNMD_01169	4.64e-106	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HEMLNNMD_01170	2.51e-201	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HEMLNNMD_01171	2.91e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HEMLNNMD_01172	1.51e-64	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HEMLNNMD_01173	1.35e-127	-	-	-	-	-	-	-	-
HEMLNNMD_01175	8.17e-31	-	-	-	-	-	-	-	-
HEMLNNMD_01179	1.46e-159	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEMLNNMD_01180	1.36e-77	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HEMLNNMD_01183	1.75e-216	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEMLNNMD_01184	0.0	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HEMLNNMD_01185	8.38e-225	-	-	-	S	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
HEMLNNMD_01186	8.54e-282	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HEMLNNMD_01187	7.98e-141	-	-	-	S	-	-	-	Phage tail protein
HEMLNNMD_01188	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEMLNNMD_01189	1.25e-16	-	-	-	-	-	-	-	-
HEMLNNMD_01190	8.17e-32	-	-	-	-	-	-	-	-
HEMLNNMD_01191	7.1e-78	-	-	-	-	-	-	-	-
HEMLNNMD_01192	1.74e-41	-	-	-	-	-	-	-	-
HEMLNNMD_01193	1.87e-63	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEMLNNMD_01194	6.18e-20	-	-	-	S	-	-	-	Phage head-tail joining protein
HEMLNNMD_01195	8.16e-31	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEMLNNMD_01196	8.81e-62	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEMLNNMD_01197	4.02e-08	-	-	-	S	-	-	-	peptidoglycan catabolic process
HEMLNNMD_01198	6.92e-227	-	-	-	S	-	-	-	capsid protein
HEMLNNMD_01199	1.51e-140	-	-	-	S	-	-	-	peptidase activity
HEMLNNMD_01200	1.47e-306	-	-	-	S	-	-	-	Phage portal protein
HEMLNNMD_01201	1.1e-14	-	-	-	-	-	-	-	-
HEMLNNMD_01202	3.89e-291	-	-	-	S	-	-	-	Phage Terminase
HEMLNNMD_01203	2.34e-113	-	-	-	S	-	-	-	Phage terminase, small subunit
HEMLNNMD_01204	1.35e-93	-	-	-	S	-	-	-	HNH endonuclease
HEMLNNMD_01206	8.89e-27	-	-	-	N	-	-	-	PFAM YcfA family protein
HEMLNNMD_01207	1.7e-96	-	-	-	S	-	-	-	regulation of transcription, DNA-dependent
HEMLNNMD_01209	2.62e-78	-	-	-	-	-	-	-	-
HEMLNNMD_01212	6.12e-106	-	-	-	-	-	-	-	-
HEMLNNMD_01213	4.84e-125	-	-	-	S	-	-	-	nuclease activity
HEMLNNMD_01214	2.76e-69	-	-	-	-	-	-	-	-
HEMLNNMD_01215	0.0	-	-	-	S	-	-	-	hydrolase activity
HEMLNNMD_01216	8.26e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HEMLNNMD_01217	1.62e-07	-	-	-	-	-	-	-	-
HEMLNNMD_01218	1.66e-218	-	-	-	S	-	-	-	AAA domain
HEMLNNMD_01219	1.8e-118	-	-	-	S	-	-	-	DNA protection
HEMLNNMD_01221	1.04e-31	-	-	-	S	-	-	-	Uncharacterized protein YqaH
HEMLNNMD_01224	5.7e-13	-	-	-	K	-	-	-	helix-turn-helix
HEMLNNMD_01225	3.65e-88	-	-	-	S	-	-	-	sequence-specific DNA binding
HEMLNNMD_01226	8.53e-104	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HEMLNNMD_01227	0.0	-	-	-	S	-	-	-	Recombinase
HEMLNNMD_01228	2.89e-88	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HEMLNNMD_01229	4.58e-128	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HEMLNNMD_01230	4.35e-193	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HEMLNNMD_01231	5.19e-109	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HEMLNNMD_01232	5.88e-295	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HEMLNNMD_01233	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEMLNNMD_01234	3.61e-34	-	-	-	-	-	-	-	-
HEMLNNMD_01235	1.35e-235	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HEMLNNMD_01236	1.29e-225	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HEMLNNMD_01237	2.87e-306	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HEMLNNMD_01238	1.7e-234	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HEMLNNMD_01239	1.17e-174	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HEMLNNMD_01240	1.73e-221	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HEMLNNMD_01241	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HEMLNNMD_01242	2.79e-311	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HEMLNNMD_01243	1.8e-110	ysxD	-	-	-	-	-	-	-
HEMLNNMD_01244	8.88e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HEMLNNMD_01245	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEMLNNMD_01246	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HEMLNNMD_01247	2.7e-295	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEMLNNMD_01248	2.96e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEMLNNMD_01249	6.44e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HEMLNNMD_01250	3.62e-148	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEMLNNMD_01251	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEMLNNMD_01252	2.66e-249	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEMLNNMD_01253	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEMLNNMD_01254	6.75e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEMLNNMD_01255	1.45e-109	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HEMLNNMD_01256	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HEMLNNMD_01261	2.08e-113	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEMLNNMD_01262	1.18e-169	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HEMLNNMD_01263	6.38e-235	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HEMLNNMD_01264	1.29e-193	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HEMLNNMD_01265	7.32e-95	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_01266	6.32e-42	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_01267	8.26e-96	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HEMLNNMD_01268	1.77e-188	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HEMLNNMD_01269	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HEMLNNMD_01270	2.73e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HEMLNNMD_01271	2.86e-102	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HEMLNNMD_01272	2.17e-268	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEMLNNMD_01273	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEMLNNMD_01274	1.6e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HEMLNNMD_01275	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HEMLNNMD_01276	1.37e-224	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HEMLNNMD_01277	5.83e-176	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HEMLNNMD_01278	1.72e-169	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HEMLNNMD_01279	1.78e-133	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_01280	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HEMLNNMD_01281	2.11e-146	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HEMLNNMD_01282	3.09e-88	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HEMLNNMD_01283	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEMLNNMD_01284	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HEMLNNMD_01285	2.02e-107	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HEMLNNMD_01286	4.23e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEMLNNMD_01287	2.43e-212	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEMLNNMD_01288	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEMLNNMD_01289	2.1e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEMLNNMD_01290	4.97e-168	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEMLNNMD_01291	8.83e-43	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HEMLNNMD_01292	6.24e-246	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HEMLNNMD_01293	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD binding domain
HEMLNNMD_01294	3.15e-312	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HEMLNNMD_01295	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HEMLNNMD_01296	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HEMLNNMD_01297	2.19e-187	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HEMLNNMD_01298	5.47e-209	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
HEMLNNMD_01299	1.98e-314	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HEMLNNMD_01300	4.76e-269	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HEMLNNMD_01301	5.57e-108	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HEMLNNMD_01302	4.89e-58	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HEMLNNMD_01303	2.82e-169	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HEMLNNMD_01304	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HEMLNNMD_01305	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HEMLNNMD_01306	2.15e-235	abnA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HEMLNNMD_01307	6.18e-262	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HEMLNNMD_01308	4.11e-82	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HEMLNNMD_01309	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEMLNNMD_01310	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HEMLNNMD_01311	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEMLNNMD_01312	4.22e-145	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HEMLNNMD_01313	7.85e-67	-	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	effector of murein hydrolase LrgA
HEMLNNMD_01314	8.26e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HEMLNNMD_01315	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_01316	2.6e-187	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HEMLNNMD_01317	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEMLNNMD_01318	6.12e-192	ytxC	-	-	S	-	-	-	YtxC-like family
HEMLNNMD_01319	2.5e-128	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HEMLNNMD_01320	2.64e-215	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HEMLNNMD_01321	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HEMLNNMD_01322	5.95e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEMLNNMD_01323	1.82e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HEMLNNMD_01324	4.24e-247	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEMLNNMD_01325	7.74e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01326	9.49e-251	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HEMLNNMD_01327	2.83e-199	ytbE	-	-	S	-	-	-	reductase
HEMLNNMD_01328	3.52e-120	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEMLNNMD_01329	4.52e-135	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEMLNNMD_01330	2.14e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEMLNNMD_01331	5.21e-62	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEMLNNMD_01332	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEMLNNMD_01333	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HEMLNNMD_01334	5.62e-165	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_01335	3.62e-218	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HEMLNNMD_01336	1.26e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HEMLNNMD_01337	8.21e-268	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEMLNNMD_01338	4.07e-129	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEMLNNMD_01339	5.32e-51	-	-	-	-	-	-	-	-
HEMLNNMD_01340	1.41e-82	-	-	-	-	-	-	-	-
HEMLNNMD_01341	6.98e-88	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEMLNNMD_01342	1.99e-33	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEMLNNMD_01343	4.67e-29	bhlA	-	-	S	-	-	-	BhlA holin family
HEMLNNMD_01346	5.13e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEMLNNMD_01347	2.7e-128	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEMLNNMD_01349	2.45e-26	-	-	-	S	-	-	-	Prophage endopeptidase tail
HEMLNNMD_01350	1.34e-58	-	-	-	S	-	-	-	Phage tail protein
HEMLNNMD_01351	7.43e-65	-	-	-	S	-	-	-	Phage-related minor tail protein
HEMLNNMD_01358	1.04e-146	-	-	-	S	-	-	-	Phage capsid family
HEMLNNMD_01359	1.1e-87	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEMLNNMD_01360	1.09e-86	-	-	-	S	-	-	-	Phage portal protein
HEMLNNMD_01361	0.0	-	-	-	S	-	-	-	Terminase
HEMLNNMD_01362	2.92e-61	-	-	-	L	-	-	-	Phage terminase, small subunit
HEMLNNMD_01363	4.23e-43	-	-	-	V	-	-	-	HNH nucleases
HEMLNNMD_01368	2.88e-26	-	-	-	N	-	-	-	PFAM YcfA family protein
HEMLNNMD_01369	3.29e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
HEMLNNMD_01370	5.62e-102	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEMLNNMD_01371	8.98e-34	-	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEMLNNMD_01372	2.27e-35	-	-	-	-	-	-	-	-
HEMLNNMD_01373	1.73e-210	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	replicative DNA helicase
HEMLNNMD_01374	2.13e-19	-	-	-	S	-	-	-	Loader and inhibitor of phage G40P
HEMLNNMD_01375	3.55e-105	-	-	-	L	-	-	-	DnaD domain protein
HEMLNNMD_01378	1.37e-89	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HEMLNNMD_01382	1.09e-38	-	-	-	-	-	-	-	-
HEMLNNMD_01383	7.95e-25	-	-	-	-	-	-	-	-
HEMLNNMD_01384	3.02e-44	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_01385	9.95e-55	-	-	-	E	-	-	-	Zn peptidase
HEMLNNMD_01386	6.03e-188	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEMLNNMD_01387	1.92e-96	ytwI	-	-	S	-	-	-	membrane
HEMLNNMD_01388	8.18e-247	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HEMLNNMD_01389	1.34e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HEMLNNMD_01390	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HEMLNNMD_01391	1.33e-228	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEMLNNMD_01392	3.28e-232	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEMLNNMD_01393	2.08e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEMLNNMD_01394	9.53e-284	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEMLNNMD_01395	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HEMLNNMD_01396	1.12e-71	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HEMLNNMD_01397	2.54e-112	ytrI	-	-	-	-	-	-	-
HEMLNNMD_01398	1.17e-30	-	-	-	-	-	-	-	-
HEMLNNMD_01399	4.26e-222	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HEMLNNMD_01400	3.44e-60	ytpI	-	-	S	-	-	-	YtpI-like protein
HEMLNNMD_01401	3.87e-303	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HEMLNNMD_01402	2.31e-163	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HEMLNNMD_01403	1.33e-180	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_01405	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HEMLNNMD_01406	8.67e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEMLNNMD_01407	3.87e-113	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HEMLNNMD_01408	2.6e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEMLNNMD_01409	2.11e-225	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HEMLNNMD_01410	1.12e-115	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HEMLNNMD_01411	4.26e-52	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HEMLNNMD_01412	1.56e-37	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HEMLNNMD_01413	2.09e-146	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HEMLNNMD_01414	1.86e-103	yteJ	-	-	S	-	-	-	RDD family
HEMLNNMD_01415	3.79e-227	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HEMLNNMD_01416	5.03e-191	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEMLNNMD_01417	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HEMLNNMD_01418	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEMLNNMD_01419	2.05e-42	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HEMLNNMD_01420	9.17e-68	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEMLNNMD_01421	5.42e-194	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEMLNNMD_01422	2.43e-69	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEMLNNMD_01423	7.24e-143	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HEMLNNMD_01424	8.89e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HEMLNNMD_01425	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEMLNNMD_01426	1.71e-163	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HEMLNNMD_01427	4.48e-137	yttP	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01428	2.38e-109	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HEMLNNMD_01429	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HEMLNNMD_01430	5.75e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEMLNNMD_01431	1e-271	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEMLNNMD_01435	1.07e-161	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HEMLNNMD_01436	9.24e-189	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEMLNNMD_01437	3.69e-189	-	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01438	7.21e-154	ygaZ	-	-	E	-	-	-	AzlC protein
HEMLNNMD_01439	7.23e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HEMLNNMD_01440	5.73e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEMLNNMD_01441	1.24e-154	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEMLNNMD_01442	6.31e-252	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HEMLNNMD_01443	3.32e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HEMLNNMD_01444	1.01e-139	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HEMLNNMD_01445	1.99e-283	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HEMLNNMD_01446	6.98e-145	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HEMLNNMD_01447	2.47e-184	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HEMLNNMD_01448	7.72e-231	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HEMLNNMD_01449	1.8e-248	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HEMLNNMD_01450	8.39e-58	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HEMLNNMD_01451	1.83e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HEMLNNMD_01452	2.16e-25	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEMLNNMD_01453	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HEMLNNMD_01454	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEMLNNMD_01455	1.05e-32	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HEMLNNMD_01456	9.89e-138	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEMLNNMD_01457	1.1e-186	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HEMLNNMD_01458	2.23e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HEMLNNMD_01459	6.48e-99	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HEMLNNMD_01460	2.06e-258	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HEMLNNMD_01461	9.96e-69	ytzB	-	-	S	-	-	-	small secreted protein
HEMLNNMD_01462	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HEMLNNMD_01463	5.74e-204	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEMLNNMD_01464	4.34e-158	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEMLNNMD_01465	6.45e-59	ytzH	-	-	S	-	-	-	YtzH-like protein
HEMLNNMD_01466	3.42e-198	ytmP	-	-	M	-	-	-	Phosphotransferase
HEMLNNMD_01467	4.56e-215	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HEMLNNMD_01468	1e-198	ytlQ	-	-	-	-	-	-	-
HEMLNNMD_01469	5.85e-128	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HEMLNNMD_01470	9.95e-215	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEMLNNMD_01471	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HEMLNNMD_01472	3.89e-286	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEMLNNMD_01473	2.01e-250	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HEMLNNMD_01474	5.76e-151	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HEMLNNMD_01475	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HEMLNNMD_01476	4.25e-160	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HEMLNNMD_01477	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEMLNNMD_01478	5.44e-292	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HEMLNNMD_01479	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HEMLNNMD_01480	1.22e-34	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HEMLNNMD_01481	3.26e-231	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_01482	4.85e-296	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HEMLNNMD_01483	1.72e-212	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEMLNNMD_01484	1.17e-183	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_01485	1.01e-312	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HEMLNNMD_01486	8.6e-94	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
HEMLNNMD_01487	7.08e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HEMLNNMD_01488	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HEMLNNMD_01489	7.19e-69	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HEMLNNMD_01490	1.79e-172	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HEMLNNMD_01491	1.78e-264	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HEMLNNMD_01492	1.03e-151	ywaF	-	-	S	-	-	-	Integral membrane protein
HEMLNNMD_01493	0.0	bceB	-	-	V	ko:K02004,ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HEMLNNMD_01494	2.57e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_01495	1.57e-208	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HEMLNNMD_01496	2.2e-158	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_01497	5.02e-258	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HEMLNNMD_01498	7.08e-160	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_01499	2.19e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HEMLNNMD_01500	1.66e-206	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEMLNNMD_01501	8.43e-216	ytrC	-	-	S	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEMLNNMD_01502	3.7e-201	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_01503	6.32e-86	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HEMLNNMD_01505	1.43e-52	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HEMLNNMD_01506	6.73e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HEMLNNMD_01507	4.07e-133	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HEMLNNMD_01509	8.82e-266	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HEMLNNMD_01510	2.23e-190	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HEMLNNMD_01511	7.46e-80	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HEMLNNMD_01512	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEMLNNMD_01513	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEMLNNMD_01514	7.88e-287	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEMLNNMD_01515	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEMLNNMD_01516	2.85e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HEMLNNMD_01517	2.06e-185	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HEMLNNMD_01518	1.22e-227	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HEMLNNMD_01519	1.38e-180	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEMLNNMD_01520	9.79e-170	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HEMLNNMD_01521	5.86e-114	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HEMLNNMD_01522	1.67e-77	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HEMLNNMD_01523	3e-98	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEMLNNMD_01525	9.99e-98	ytkA	-	-	S	-	-	-	YtkA-like
HEMLNNMD_01526	7.16e-114	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEMLNNMD_01527	5.71e-52	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HEMLNNMD_01528	4.26e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HEMLNNMD_01529	4.14e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HEMLNNMD_01530	6.36e-313	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HEMLNNMD_01531	1.01e-232	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HEMLNNMD_01532	3.45e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HEMLNNMD_01533	2.54e-266	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HEMLNNMD_01534	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEMLNNMD_01535	7.22e-198	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEMLNNMD_01536	1.68e-188	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HEMLNNMD_01537	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HEMLNNMD_01538	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HEMLNNMD_01539	8.57e-160	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HEMLNNMD_01540	9.33e-96	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HEMLNNMD_01562	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_01563	4.32e-119	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HEMLNNMD_01564	1.38e-273	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HEMLNNMD_01565	1.04e-104	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HEMLNNMD_01566	4.75e-101	yuaE	-	-	S	-	-	-	DinB superfamily
HEMLNNMD_01567	1.21e-134	-	-	-	S	-	-	-	MOSC domain
HEMLNNMD_01568	9.64e-288	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HEMLNNMD_01569	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEMLNNMD_01570	4.78e-119	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HEMLNNMD_01571	4.6e-119	yuaB	-	-	-	-	-	-	-
HEMLNNMD_01572	1.97e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HEMLNNMD_01573	2.76e-186	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEMLNNMD_01574	6.52e-270	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HEMLNNMD_01575	2.3e-142	-	-	-	G	-	-	-	Cupin
HEMLNNMD_01576	6.21e-59	yjcN	-	-	-	-	-	-	-
HEMLNNMD_01579	2.15e-177	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HEMLNNMD_01580	7.36e-20	-	-	-	-	-	-	-	-
HEMLNNMD_01582	7.33e-184	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEMLNNMD_01583	2.73e-248	yubA	-	-	S	-	-	-	transporter activity
HEMLNNMD_01584	4.84e-231	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HEMLNNMD_01585	5.71e-126	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HEMLNNMD_01586	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEMLNNMD_01587	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEMLNNMD_01588	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEMLNNMD_01589	3.66e-284	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HEMLNNMD_01590	4.12e-175	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HEMLNNMD_01591	1.82e-52	-	-	-	-	-	-	-	-
HEMLNNMD_01592	1.07e-237	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HEMLNNMD_01593	8.06e-96	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HEMLNNMD_01594	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEMLNNMD_01595	1.82e-293	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEMLNNMD_01596	1.95e-149	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HEMLNNMD_01597	3.56e-22	-	-	-	-	-	-	-	-
HEMLNNMD_01598	8.53e-36	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HEMLNNMD_01599	8.97e-227	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HEMLNNMD_01600	2.91e-42	yugN	-	-	S	-	-	-	YugN-like family
HEMLNNMD_01601	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HEMLNNMD_01602	3.35e-125	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HEMLNNMD_01603	4e-148	ycaC	-	-	Q	-	-	-	Isochorismatase family
HEMLNNMD_01604	8.85e-288	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HEMLNNMD_01605	3.72e-283	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HEMLNNMD_01606	1.28e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HEMLNNMD_01607	8.3e-82	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HEMLNNMD_01608	1.79e-261	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HEMLNNMD_01609	1.53e-108	alaR	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01610	5.7e-155	yugF	-	-	I	-	-	-	Hydrolase
HEMLNNMD_01611	7.97e-51	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HEMLNNMD_01612	4.65e-277	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HEMLNNMD_01613	3.78e-75	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_01614	3.71e-160	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_01615	3.54e-82	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HEMLNNMD_01616	7.27e-151	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HEMLNNMD_01617	2.6e-240	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HEMLNNMD_01618	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HEMLNNMD_01619	1.27e-59	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_01620	4.19e-97	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HEMLNNMD_01621	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEMLNNMD_01622	3.8e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HEMLNNMD_01623	3.92e-247	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HEMLNNMD_01624	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_01625	1.68e-232	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEMLNNMD_01626	4.39e-218	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEMLNNMD_01628	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HEMLNNMD_01629	8.6e-88	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEMLNNMD_01630	1.42e-65	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEMLNNMD_01631	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEMLNNMD_01632	3.04e-15	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEMLNNMD_01633	2.29e-46	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEMLNNMD_01634	1.84e-50	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HEMLNNMD_01635	2.84e-77	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HEMLNNMD_01636	3.55e-77	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HEMLNNMD_01637	3.29e-147	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEMLNNMD_01638	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_01640	2.98e-123	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HEMLNNMD_01641	1.87e-11	-	-	-	S	-	-	-	DegQ (SacQ) family
HEMLNNMD_01642	1.36e-63	yuzC	-	-	-	-	-	-	-
HEMLNNMD_01643	8.35e-92	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HEMLNNMD_01644	3.46e-172	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HEMLNNMD_01645	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEMLNNMD_01646	7.41e-131	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HEMLNNMD_01647	4.96e-86	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HEMLNNMD_01648	1.57e-50	yueH	-	-	S	-	-	-	YueH-like protein
HEMLNNMD_01649	4.3e-44	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HEMLNNMD_01650	1.15e-232	yueF	-	-	S	-	-	-	transporter activity
HEMLNNMD_01651	1.98e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HEMLNNMD_01652	9.08e-124	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HEMLNNMD_01653	4.06e-160	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_01654	3e-97	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HEMLNNMD_01655	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HEMLNNMD_01656	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HEMLNNMD_01657	3.32e-259	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HEMLNNMD_01658	6.65e-51	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HEMLNNMD_01659	1.94e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HEMLNNMD_01660	1.46e-81	yukF	-	-	QT	-	-	-	Transcriptional regulator
HEMLNNMD_01661	2.93e-194	yukF	-	-	QT	-	-	-	Transcriptional regulator
HEMLNNMD_01662	1.83e-257	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HEMLNNMD_01663	1.11e-164	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HEMLNNMD_01664	3.6e-42	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HEMLNNMD_01665	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_01666	6.77e-175	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HEMLNNMD_01667	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HEMLNNMD_01668	4.99e-273	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HEMLNNMD_01669	2.65e-166	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_01670	3.14e-196	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HEMLNNMD_01671	1.48e-151	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HEMLNNMD_01672	4.35e-130	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HEMLNNMD_01673	7.47e-272	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HEMLNNMD_01674	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HEMLNNMD_01675	1.18e-99	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HEMLNNMD_01676	2.23e-149	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_01677	8.54e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
HEMLNNMD_01678	3.83e-297	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEMLNNMD_01679	1.15e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HEMLNNMD_01681	1.29e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEMLNNMD_01682	1.42e-58	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HEMLNNMD_01683	1.21e-21	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HEMLNNMD_01684	2.09e-167	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_01687	4.13e-125	res	-	-	L	-	-	-	Resolvase, N terminal domain
HEMLNNMD_01689	1.14e-236	-	-	-	KLT	-	-	-	Protein tyrosine kinase
HEMLNNMD_01690	1.2e-101	-	-	-	-	-	-	-	-
HEMLNNMD_01694	6.87e-53	-	-	-	L	-	-	-	ATP-dependent DNA helicase
HEMLNNMD_01695	1.45e-205	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEMLNNMD_01696	4.44e-79	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HEMLNNMD_01697	8.81e-205	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEMLNNMD_01698	2.57e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEMLNNMD_01699	8e-49	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HEMLNNMD_01700	3.17e-261	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEMLNNMD_01701	6.39e-71	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_01702	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HEMLNNMD_01703	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HEMLNNMD_01704	4.48e-206	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEMLNNMD_01705	5.18e-248	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HEMLNNMD_01706	1.6e-305	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HEMLNNMD_01707	1.36e-244	yutH	-	-	S	-	-	-	Spore coat protein
HEMLNNMD_01708	1.07e-108	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HEMLNNMD_01709	1.96e-178	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEMLNNMD_01710	3e-93	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HEMLNNMD_01711	3.71e-62	yutD	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_01712	3.92e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HEMLNNMD_01713	1.26e-245	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HEMLNNMD_01714	1.53e-164	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HEMLNNMD_01715	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEMLNNMD_01716	5.58e-182	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEMLNNMD_01717	7.05e-215	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HEMLNNMD_01718	2.23e-73	-	-	-	S	-	-	-	phosphoglycolate phosphatase activity
HEMLNNMD_01719	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HEMLNNMD_01720	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HEMLNNMD_01721	6.3e-86	-	-	-	-	-	-	-	-
HEMLNNMD_01722	1.08e-267	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_01723	1.04e-286	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HEMLNNMD_01724	5.1e-196	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEMLNNMD_01725	1.5e-72	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEMLNNMD_01726	2.74e-208	bsn	-	-	L	-	-	-	Ribonuclease
HEMLNNMD_01727	1.32e-161	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_01728	7.09e-69	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_01729	1.62e-170	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HEMLNNMD_01730	4.19e-203	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HEMLNNMD_01731	2.91e-199	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HEMLNNMD_01732	7.16e-201	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEMLNNMD_01733	2.27e-305	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HEMLNNMD_01734	1.06e-234	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HEMLNNMD_01735	9.63e-26	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEMLNNMD_01737	1.36e-84	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HEMLNNMD_01738	6.28e-251	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HEMLNNMD_01739	1.33e-54	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HEMLNNMD_01740	2.91e-93	yncE	-	-	S	-	-	-	Protein of unknown function (DUF2691)
HEMLNNMD_01741	7.94e-171	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HEMLNNMD_01742	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HEMLNNMD_01743	8.89e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HEMLNNMD_01744	1.23e-293	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEMLNNMD_01745	1.75e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HEMLNNMD_01746	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HEMLNNMD_01747	2.97e-83	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HEMLNNMD_01748	4.1e-183	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HEMLNNMD_01749	1.15e-135	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HEMLNNMD_01750	8.74e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEMLNNMD_01751	5.08e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HEMLNNMD_01752	2.25e-70	yusE	-	-	CO	-	-	-	Thioredoxin
HEMLNNMD_01753	6.71e-77	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HEMLNNMD_01754	2.99e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HEMLNNMD_01755	1.19e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HEMLNNMD_01756	1.39e-81	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HEMLNNMD_01757	1.48e-247	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEMLNNMD_01758	8.43e-144	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HEMLNNMD_01759	1.5e-275	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HEMLNNMD_01760	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HEMLNNMD_01761	1.72e-10	-	-	-	S	-	-	-	YuzL-like protein
HEMLNNMD_01762	6.14e-205	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HEMLNNMD_01763	7.03e-53	-	-	-	-	-	-	-	-
HEMLNNMD_01764	3.53e-69	yusN	-	-	M	-	-	-	Coat F domain
HEMLNNMD_01765	1.47e-86	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HEMLNNMD_01766	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HEMLNNMD_01767	1.46e-50	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HEMLNNMD_01768	1.06e-191	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEMLNNMD_01769	1.53e-28	-	-	-	S	-	-	-	YusW-like protein
HEMLNNMD_01770	1.19e-24	-	-	-	S	-	-	-	YusW-like protein
HEMLNNMD_01771	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HEMLNNMD_01772	4.34e-178	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_01773	1.38e-101	dps2	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HEMLNNMD_01774	5.23e-296	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEMLNNMD_01775	1.69e-159	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_01776	2.77e-316	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_01777	2.68e-32	-	-	-	-	-	-	-	-
HEMLNNMD_01778	6.7e-196	yuxN	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01779	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEMLNNMD_01780	1.83e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HEMLNNMD_01781	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HEMLNNMD_01782	6.05e-235	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HEMLNNMD_01783	1.46e-244	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HEMLNNMD_01784	8.35e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEMLNNMD_01785	3.48e-247	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_01786	6.74e-159	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HEMLNNMD_01787	4.64e-166	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HEMLNNMD_01788	2.98e-128	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HEMLNNMD_01789	1.05e-64	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HEMLNNMD_01790	9.45e-281	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_01791	9.16e-124	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HEMLNNMD_01792	3.6e-255	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HEMLNNMD_01793	4.7e-223	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_01794	4.34e-211	yvrC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEMLNNMD_01795	1.43e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_01796	2.36e-213	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HEMLNNMD_01797	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HEMLNNMD_01798	4.48e-171	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_01799	1.14e-48	-	-	-	-	-	-	-	-
HEMLNNMD_01800	1.53e-132	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HEMLNNMD_01801	1.88e-21	-	-	-	S	-	-	-	YvrJ protein family
HEMLNNMD_01802	9.98e-292	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HEMLNNMD_01803	8.29e-80	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HEMLNNMD_01804	1.62e-187	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEMLNNMD_01805	4.01e-218	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_01806	2.48e-233	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_01807	2.48e-225	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HEMLNNMD_01808	4.59e-155	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HEMLNNMD_01809	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HEMLNNMD_01810	3.93e-16	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HEMLNNMD_01811	1.68e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HEMLNNMD_01812	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HEMLNNMD_01813	3.02e-177	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HEMLNNMD_01814	1.49e-08	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HEMLNNMD_01815	4.22e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HEMLNNMD_01816	1.21e-128	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HEMLNNMD_01817	8.82e-146	yfiK	-	-	K	-	-	-	Regulator
HEMLNNMD_01818	1.22e-236	-	-	-	T	-	-	-	Histidine kinase
HEMLNNMD_01819	1.31e-215	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HEMLNNMD_01820	3e-234	sagH	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEMLNNMD_01821	1.23e-230	sagI	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HEMLNNMD_01822	1.2e-198	yvgN	-	-	S	-	-	-	reductase
HEMLNNMD_01823	6.3e-110	yvgO	-	-	-	-	-	-	-
HEMLNNMD_01824	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HEMLNNMD_01825	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HEMLNNMD_01826	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HEMLNNMD_01827	1.18e-198	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEMLNNMD_01828	8.71e-262	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEMLNNMD_01829	9.04e-130	yvgT	-	-	S	-	-	-	membrane
HEMLNNMD_01830	1.75e-186	-	-	-	S	-	-	-	Metallo-peptidase family M12
HEMLNNMD_01831	2.51e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HEMLNNMD_01832	2.06e-134	bdbD	-	-	O	-	-	-	Thioredoxin
HEMLNNMD_01833	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HEMLNNMD_01834	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HEMLNNMD_01835	3.12e-38	-	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
HEMLNNMD_01836	2.05e-61	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HEMLNNMD_01837	1.71e-240	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HEMLNNMD_01838	5.95e-153	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEMLNNMD_01839	1.63e-314	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_01840	5.43e-57	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
HEMLNNMD_01841	6.72e-221	ytmO	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_01842	2.48e-178	tcyN	-	-	E	ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEMLNNMD_01843	2.95e-149	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEMLNNMD_01844	1.57e-151	ytmL	-	-	P	ko:K16958,ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEMLNNMD_01845	1.27e-181	tcyK	-	-	M	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HEMLNNMD_01846	1.74e-162	-	-	-	ET	ko:K16956,ko:K16957,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HEMLNNMD_01847	2.71e-129	ytmI	-	-	K	ko:K00680	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HEMLNNMD_01848	1.14e-203	ytlI	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
HEMLNNMD_01849	6.26e-177	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HEMLNNMD_01850	2.5e-60	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HEMLNNMD_01852	4.85e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HEMLNNMD_01853	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEMLNNMD_01854	6.92e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HEMLNNMD_01855	9.24e-36	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HEMLNNMD_01856	1.64e-47	yvzC	-	-	K	-	-	-	transcriptional
HEMLNNMD_01857	1.02e-84	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HEMLNNMD_01858	1.09e-90	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HEMLNNMD_01859	1.17e-67	yvaP	-	-	K	-	-	-	transcriptional
HEMLNNMD_01860	1.05e-309	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HEMLNNMD_01861	5.04e-154	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
HEMLNNMD_01862	6.18e-164	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEMLNNMD_01863	6.39e-153	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HEMLNNMD_01864	7.05e-158	spaF	-	-	V	ko:K01990,ko:K20459,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_01865	4.93e-143	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEMLNNMD_01866	2.26e-213	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEMLNNMD_01867	4.44e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEMLNNMD_01868	3.58e-262	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEMLNNMD_01869	3.5e-108	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HEMLNNMD_01870	1.2e-138	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEMLNNMD_01871	4.95e-217	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HEMLNNMD_01872	5.4e-143	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HEMLNNMD_01873	3.48e-268	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HEMLNNMD_01874	2.67e-125	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HEMLNNMD_01875	1.18e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HEMLNNMD_01876	1.92e-150	yvbI	-	-	M	-	-	-	Membrane
HEMLNNMD_01877	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HEMLNNMD_01878	5.07e-103	yvbK	-	-	K	-	-	-	acetyltransferase
HEMLNNMD_01879	5.9e-260	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HEMLNNMD_01880	2.66e-219	-	-	-	-	-	-	-	-
HEMLNNMD_01881	3.54e-159	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HEMLNNMD_01882	2.98e-153	-	-	-	C	-	-	-	WbqC-like protein family
HEMLNNMD_01883	2.49e-179	-	-	-	M	-	-	-	Protein involved in cellulose biosynthesis
HEMLNNMD_01884	5.78e-165	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEMLNNMD_01885	7.19e-69	-	-	-	E	-	-	-	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HEMLNNMD_01886	1.31e-214	arnA	4.2.1.46, 5.1.3.2	-	M	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
HEMLNNMD_01887	1.81e-273	-	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HEMLNNMD_01888	2.73e-192	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEMLNNMD_01889	8.09e-286	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HEMLNNMD_01890	9.69e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEMLNNMD_01891	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HEMLNNMD_01892	1.49e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEMLNNMD_01893	4.45e-274	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HEMLNNMD_01894	2.83e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEMLNNMD_01895	8.1e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEMLNNMD_01897	0.0	araE	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEMLNNMD_01898	7.16e-257	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HEMLNNMD_01899	4.16e-218	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_01900	5.29e-161	yvbU	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01901	5.35e-196	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HEMLNNMD_01902	6.69e-275	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEMLNNMD_01904	1.01e-190	gntR	-	-	K	-	-	-	RpiR family transcriptional regulator
HEMLNNMD_01905	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HEMLNNMD_01906	5.33e-288	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HEMLNNMD_01907	3.8e-168	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEMLNNMD_01908	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HEMLNNMD_01909	1.69e-170	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HEMLNNMD_01910	8.82e-266	-	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEMLNNMD_01911	1.16e-151	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HEMLNNMD_01912	5.11e-300	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEMLNNMD_01913	7.36e-40	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HEMLNNMD_01914	1.97e-294	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HEMLNNMD_01915	4.01e-44	yvfG	-	-	S	-	-	-	YvfG protein
HEMLNNMD_01916	1.43e-226	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HEMLNNMD_01917	5.64e-275	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HEMLNNMD_01918	1.2e-68	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HEMLNNMD_01919	1.4e-133	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEMLNNMD_01920	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEMLNNMD_01921	1.25e-241	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEMLNNMD_01922	2.19e-249	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HEMLNNMD_01923	8.53e-245	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HEMLNNMD_01924	5.24e-257	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HEMLNNMD_01925	1.54e-250	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HEMLNNMD_01926	1.99e-199	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEMLNNMD_01927	3.63e-270	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HEMLNNMD_01928	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HEMLNNMD_01929	5.18e-150	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HEMLNNMD_01930	3.08e-151	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HEMLNNMD_01931	5.95e-101	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HEMLNNMD_01932	1.01e-310	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HEMLNNMD_01934	3.95e-109	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HEMLNNMD_01935	3.14e-166	-	-	-	CH	-	-	-	FAD binding domain
HEMLNNMD_01936	4.49e-96	glx2	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HEMLNNMD_01937	4.11e-134	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HEMLNNMD_01938	8.61e-107	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEMLNNMD_01939	7.09e-121	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HEMLNNMD_01940	3.95e-67	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HEMLNNMD_01941	2.05e-17	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEMLNNMD_01942	5.99e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HEMLNNMD_01943	3.64e-290	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HEMLNNMD_01944	2.17e-44	-	-	-	-	-	-	-	-
HEMLNNMD_01946	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEMLNNMD_01947	8.04e-278	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
HEMLNNMD_01948	3.26e-227	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HEMLNNMD_01949	3.74e-136	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEMLNNMD_01950	1.4e-202	yraN	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_01951	6.94e-262	yraM	-	-	S	-	-	-	PrpF protein
HEMLNNMD_01952	1.99e-314	-	-	-	EGP	-	-	-	Sugar (and other) transporter
HEMLNNMD_01953	5.28e-111	-	-	-	-	-	-	-	-
HEMLNNMD_01954	2.87e-132	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HEMLNNMD_01955	9.93e-65	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HEMLNNMD_01956	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HEMLNNMD_01957	8.55e-135	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HEMLNNMD_01958	1.82e-227	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEMLNNMD_01959	4.11e-100	-	-	-	M	-	-	-	Ribonuclease
HEMLNNMD_01960	1.12e-119	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HEMLNNMD_01961	3.53e-24	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HEMLNNMD_01962	6.52e-49	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HEMLNNMD_01963	5.16e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HEMLNNMD_01964	6.55e-60	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HEMLNNMD_01965	2.76e-145	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HEMLNNMD_01966	1.41e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HEMLNNMD_01967	2.86e-112	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEMLNNMD_01968	4.78e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEMLNNMD_01969	4.88e-195	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HEMLNNMD_01970	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HEMLNNMD_01971	1.17e-230	sasA	-	-	T	-	-	-	Histidine kinase
HEMLNNMD_01972	4.28e-153	mprA3	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_01973	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HEMLNNMD_01974	7.18e-138	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HEMLNNMD_01975	5.63e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEMLNNMD_01976	9.97e-162	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEMLNNMD_01977	2.13e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEMLNNMD_01978	7.58e-134	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HEMLNNMD_01979	2.03e-280	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEMLNNMD_01980	1.45e-145	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEMLNNMD_01981	7.1e-257	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HEMLNNMD_01982	3.83e-173	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HEMLNNMD_01983	1.2e-110	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HEMLNNMD_01984	1.91e-156	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HEMLNNMD_01985	1.76e-193	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEMLNNMD_01986	6e-216	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEMLNNMD_01987	1.22e-272	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEMLNNMD_01988	1.44e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEMLNNMD_01989	5.85e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HEMLNNMD_01991	6.76e-131	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HEMLNNMD_01992	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HEMLNNMD_01993	1.09e-65	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HEMLNNMD_01994	8.1e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HEMLNNMD_01995	2.91e-214	yvlB	-	-	S	-	-	-	Putative adhesin
HEMLNNMD_01996	1.79e-61	yvlA	-	-	-	-	-	-	-
HEMLNNMD_01997	1.29e-40	yvkN	-	-	-	-	-	-	-
HEMLNNMD_01998	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEMLNNMD_01999	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEMLNNMD_02000	2.59e-45	csbA	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02001	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HEMLNNMD_02002	1.59e-119	yvkB	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02003	3.49e-290	yvkA	-	-	P	-	-	-	-transporter
HEMLNNMD_02005	5.67e-278	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEMLNNMD_02006	5.83e-72	swrA	-	-	S	-	-	-	Swarming motility protein
HEMLNNMD_02007	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HEMLNNMD_02008	2.11e-275	ywoF	-	-	P	-	-	-	Right handed beta helix region
HEMLNNMD_02009	1.48e-196	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEMLNNMD_02010	3.53e-158	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HEMLNNMD_02011	1.2e-57	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HEMLNNMD_02012	5.39e-189	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEMLNNMD_02013	1.08e-222	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEMLNNMD_02014	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEMLNNMD_02015	4.25e-130	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEMLNNMD_02016	1.92e-89	-	-	-	-	-	-	-	-
HEMLNNMD_02017	1.57e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HEMLNNMD_02018	2.18e-83	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HEMLNNMD_02019	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HEMLNNMD_02020	1.42e-153	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HEMLNNMD_02021	2.67e-43	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HEMLNNMD_02022	5.2e-98	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HEMLNNMD_02023	2.99e-103	yviE	-	-	-	-	-	-	-
HEMLNNMD_02024	6.64e-206	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HEMLNNMD_02025	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HEMLNNMD_02026	1.43e-101	yvyG	-	-	NOU	-	-	-	FlgN protein
HEMLNNMD_02027	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HEMLNNMD_02028	6.15e-95	yvyF	-	-	S	-	-	-	flagellar protein
HEMLNNMD_02029	2.57e-81	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HEMLNNMD_02030	2.93e-56	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HEMLNNMD_02031	6.13e-315	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HEMLNNMD_02032	9.46e-199	degV	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02033	7.16e-163	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEMLNNMD_02034	2.31e-245	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HEMLNNMD_02035	6.65e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HEMLNNMD_02036	4.55e-234	yvhJ	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02037	8.94e-233	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HEMLNNMD_02038	3.2e-285	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HEMLNNMD_02039	9.06e-182	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HEMLNNMD_02040	8.08e-138	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HEMLNNMD_02041	0.0	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HEMLNNMD_02042	3.03e-312	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEMLNNMD_02043	2.27e-269	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HEMLNNMD_02044	0.0	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEMLNNMD_02045	8.51e-151	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HEMLNNMD_02046	0.0	lytC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEMLNNMD_02047	0.0	lytB	-	-	D	-	-	-	Stage II sporulation protein
HEMLNNMD_02048	6.25e-63	-	-	-	-	-	-	-	-
HEMLNNMD_02049	2.48e-201	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HEMLNNMD_02050	1.62e-263	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEMLNNMD_02051	4.2e-208	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HEMLNNMD_02052	0.0	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HEMLNNMD_02053	5.06e-195	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HEMLNNMD_02054	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEMLNNMD_02055	1.48e-88	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HEMLNNMD_02056	1.22e-253	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HEMLNNMD_02057	2.69e-91	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HEMLNNMD_02058	1.18e-179	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HEMLNNMD_02059	3.95e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HEMLNNMD_02060	1.91e-294	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEMLNNMD_02061	1.7e-234	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEMLNNMD_02062	0.0	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HEMLNNMD_02063	3.04e-221	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HEMLNNMD_02064	4.89e-262	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HEMLNNMD_02065	0.0	-	-	-	J	ko:K07011	-	ko00000	Glycosyl transferase family 2
HEMLNNMD_02066	9.21e-304	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEMLNNMD_02067	1.2e-221	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02068	1.33e-195	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEMLNNMD_02069	5.61e-60	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HEMLNNMD_02070	4.57e-287	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEMLNNMD_02071	1.16e-28	ywtC	-	-	-	-	-	-	-
HEMLNNMD_02072	7.41e-276	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HEMLNNMD_02073	2.95e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HEMLNNMD_02074	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HEMLNNMD_02075	6.6e-244	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HEMLNNMD_02076	3.29e-226	-	-	-	E	-	-	-	Spore germination protein
HEMLNNMD_02077	1.59e-247	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
HEMLNNMD_02078	1.08e-221	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
HEMLNNMD_02079	6.79e-193	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEMLNNMD_02080	3.64e-81	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEMLNNMD_02081	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HEMLNNMD_02082	7.29e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HEMLNNMD_02083	1.1e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HEMLNNMD_02084	5.4e-112	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HEMLNNMD_02085	1.22e-114	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HEMLNNMD_02086	4.33e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HEMLNNMD_02087	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HEMLNNMD_02088	6.98e-211	alsR	-	-	K	-	-	-	LysR substrate binding domain
HEMLNNMD_02090	2.8e-295	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEMLNNMD_02091	8.96e-150	ywrJ	-	-	-	-	-	-	-
HEMLNNMD_02092	2.39e-161	cotB	-	-	-	ko:K06325	-	ko00000	-
HEMLNNMD_02093	2.14e-259	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HEMLNNMD_02094	2.4e-09	-	-	-	-	-	-	-	-
HEMLNNMD_02095	4.9e-143	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HEMLNNMD_02097	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HEMLNNMD_02098	9.36e-106	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HEMLNNMD_02099	1.24e-124	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HEMLNNMD_02100	2.03e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HEMLNNMD_02101	5.23e-130	-	-	-	-	-	-	-	-
HEMLNNMD_02102	2.39e-81	-	-	-	-	-	-	-	-
HEMLNNMD_02103	1.92e-25	-	-	-	-	-	-	-	-
HEMLNNMD_02104	5.41e-76	-	-	-	S	-	-	-	SUKH-4 immunity protein
HEMLNNMD_02105	5.72e-290	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HEMLNNMD_02106	1.36e-48	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HEMLNNMD_02108	7.14e-184	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HEMLNNMD_02109	6.02e-305	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEMLNNMD_02110	3.26e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HEMLNNMD_02111	3.37e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HEMLNNMD_02112	1.7e-143	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HEMLNNMD_02113	3e-22	-	-	-	-	-	-	-	-
HEMLNNMD_02114	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HEMLNNMD_02115	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HEMLNNMD_02116	5.43e-195	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HEMLNNMD_02117	2.67e-178	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HEMLNNMD_02118	4.94e-75	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HEMLNNMD_02119	1.83e-74	ywpG	-	-	-	-	-	-	-
HEMLNNMD_02120	1.44e-32	ywpF	-	-	S	-	-	-	YwpF-like protein
HEMLNNMD_02121	1.41e-45	ywpF	-	-	S	-	-	-	YwpF-like protein
HEMLNNMD_02122	2.54e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEMLNNMD_02123	6.36e-98	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEMLNNMD_02124	4.41e-247	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HEMLNNMD_02125	1.25e-176	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HEMLNNMD_02126	1.16e-170	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HEMLNNMD_02127	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HEMLNNMD_02128	5.93e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HEMLNNMD_02129	1.07e-92	ywoH	-	-	K	-	-	-	transcriptional
HEMLNNMD_02130	1e-258	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_02131	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HEMLNNMD_02132	1.28e-308	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HEMLNNMD_02133	2.1e-128	yjgF	-	-	Q	-	-	-	Isochorismatase family
HEMLNNMD_02134	1.91e-205	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HEMLNNMD_02135	3.17e-71	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HEMLNNMD_02136	1.07e-75	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HEMLNNMD_02137	3.87e-263	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HEMLNNMD_02138	5.56e-130	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HEMLNNMD_02139	1.44e-89	ywnJ	-	-	S	-	-	-	VanZ like family
HEMLNNMD_02140	1.17e-175	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HEMLNNMD_02141	7.6e-113	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HEMLNNMD_02143	2.45e-88	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HEMLNNMD_02144	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEMLNNMD_02145	2.8e-79	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HEMLNNMD_02146	4.57e-117	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HEMLNNMD_02147	3.09e-88	ywnA	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02148	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HEMLNNMD_02149	4.37e-81	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HEMLNNMD_02150	2.26e-65	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HEMLNNMD_02151	2.41e-16	csbD	-	-	K	-	-	-	CsbD-like
HEMLNNMD_02152	2.48e-106	ywmF	-	-	S	-	-	-	Peptidase M50
HEMLNNMD_02153	1.02e-114	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEMLNNMD_02154	3.46e-242	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEMLNNMD_02155	2.05e-183	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HEMLNNMD_02157	2.79e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEMLNNMD_02158	4.74e-145	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEMLNNMD_02159	8.36e-233	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HEMLNNMD_02160	1.85e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEMLNNMD_02161	4.45e-170	ywmB	-	-	S	-	-	-	TATA-box binding
HEMLNNMD_02162	7.55e-44	ywzB	-	-	S	-	-	-	membrane
HEMLNNMD_02163	1.98e-115	ywmA	-	-	-	-	-	-	-
HEMLNNMD_02164	3.36e-82	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HEMLNNMD_02165	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEMLNNMD_02166	1.1e-195	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEMLNNMD_02167	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEMLNNMD_02168	5.59e-116	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEMLNNMD_02169	3.35e-82	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEMLNNMD_02170	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEMLNNMD_02171	5.19e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HEMLNNMD_02172	4.49e-80	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HEMLNNMD_02173	1.3e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEMLNNMD_02174	5.69e-299	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEMLNNMD_02175	1.44e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HEMLNNMD_02176	9.2e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HEMLNNMD_02177	1.84e-95	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEMLNNMD_02178	5.32e-116	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HEMLNNMD_02179	2.33e-238	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEMLNNMD_02180	6.75e-96	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HEMLNNMD_02181	2.87e-147	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HEMLNNMD_02182	3.32e-76	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HEMLNNMD_02184	1.01e-195	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEMLNNMD_02185	2.06e-240	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEMLNNMD_02186	2.41e-84	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEMLNNMD_02187	3.73e-117	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HEMLNNMD_02188	6.87e-194	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HEMLNNMD_02189	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HEMLNNMD_02190	6.49e-131	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HEMLNNMD_02191	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HEMLNNMD_02192	5.13e-304	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HEMLNNMD_02193	9.65e-223	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HEMLNNMD_02194	1.59e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEMLNNMD_02195	3.69e-143	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HEMLNNMD_02196	4.53e-203	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HEMLNNMD_02197	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HEMLNNMD_02198	2.24e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HEMLNNMD_02199	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEMLNNMD_02200	1.97e-74	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEMLNNMD_02201	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HEMLNNMD_02202	3.56e-262	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HEMLNNMD_02203	3.25e-225	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HEMLNNMD_02204	3.23e-58	ywjC	-	-	-	-	-	-	-
HEMLNNMD_02205	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEMLNNMD_02206	0.0	ywiE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEMLNNMD_02207	1.61e-149	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase (gamma
HEMLNNMD_02208	8.77e-110	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	nitrate reductase
HEMLNNMD_02209	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
HEMLNNMD_02210	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEMLNNMD_02211	1e-97	arfM	-	-	T	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	cyclic nucleotide binding
HEMLNNMD_02212	2.46e-161	ywiC	-	-	S	-	-	-	YwiC-like protein
HEMLNNMD_02213	7.09e-163	fnr	-	-	K	-	-	-	helix_turn_helix, cAMP Regulatory protein
HEMLNNMD_02214	3.08e-266	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HEMLNNMD_02215	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HEMLNNMD_02216	1.09e-94	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02218	5.71e-251	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HEMLNNMD_02219	5.55e-103	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEMLNNMD_02221	2.45e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HEMLNNMD_02222	6.45e-203	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEMLNNMD_02223	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEMLNNMD_02224	1.61e-92	-	-	-	-	-	-	-	-
HEMLNNMD_02225	2.07e-116	ywhD	-	-	S	-	-	-	YwhD family
HEMLNNMD_02226	1.1e-152	ywhC	-	-	S	-	-	-	Peptidase family M50
HEMLNNMD_02227	2.37e-34	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HEMLNNMD_02228	3.29e-90	ywhA	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02229	6.8e-307	potE5	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HEMLNNMD_02230	1.37e-113	ywgA	-	-	-	ko:K09388	-	ko00000	-
HEMLNNMD_02231	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HEMLNNMD_02232	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HEMLNNMD_02233	6.18e-139	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HEMLNNMD_02234	2.99e-65	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
HEMLNNMD_02235	2.51e-109	-	-	-	S	-	-	-	membrane
HEMLNNMD_02236	2.86e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_02237	2.13e-208	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_02240	1.87e-209	-	-	-	-	-	-	-	-
HEMLNNMD_02242	8.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HEMLNNMD_02243	1.33e-199	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_02244	9.29e-207	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HEMLNNMD_02245	2.27e-222	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HEMLNNMD_02246	1.9e-184	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HEMLNNMD_02247	2.12e-179	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HEMLNNMD_02248	2.27e-290	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HEMLNNMD_02249	9.5e-264	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HEMLNNMD_02250	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HEMLNNMD_02251	4.47e-178	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_02252	6.12e-172	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HEMLNNMD_02253	1.83e-142	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HEMLNNMD_02254	1.97e-277	ywfA	-	-	EGP	-	-	-	-transporter
HEMLNNMD_02255	1.86e-253	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HEMLNNMD_02256	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEMLNNMD_02257	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HEMLNNMD_02258	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEMLNNMD_02259	5e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HEMLNNMD_02260	4.02e-80	-	-	-	-	-	-	-	-
HEMLNNMD_02261	2.6e-109	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HEMLNNMD_02262	5.7e-200	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEMLNNMD_02263	1.33e-226	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEMLNNMD_02264	4.12e-170	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEMLNNMD_02265	2.22e-214	spsG	-	-	M	-	-	-	Spore Coat
HEMLNNMD_02266	1.52e-159	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HEMLNNMD_02267	5.99e-266	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HEMLNNMD_02268	6.34e-195	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HEMLNNMD_02269	4.47e-276	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HEMLNNMD_02270	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HEMLNNMD_02271	1.18e-179	spsA	-	-	M	-	-	-	Spore Coat
HEMLNNMD_02272	1.83e-83	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HEMLNNMD_02273	1.79e-75	ywdK	-	-	S	-	-	-	small membrane protein
HEMLNNMD_02274	6e-288	ywdJ	-	-	F	-	-	-	Xanthine uracil
HEMLNNMD_02275	9.54e-57	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HEMLNNMD_02276	2.42e-169	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEMLNNMD_02277	1.44e-186	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HEMLNNMD_02278	2.79e-185	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEMLNNMD_02279	6.09e-27	ywdA	-	-	-	-	-	-	-
HEMLNNMD_02280	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HEMLNNMD_02281	4.52e-316	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_02282	1.29e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HEMLNNMD_02284	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEMLNNMD_02285	5.76e-83	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEMLNNMD_02286	6.39e-234	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_02287	1.46e-149	-	-	-	K	-	-	-	WYL domain
HEMLNNMD_02288	2.11e-162	ucpA	-	-	IQ	-	-	-	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_02289	1.08e-54	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
HEMLNNMD_02290	4.81e-42	-	-	-	S	-	-	-	Stress responsive A/B Barrel Domain
HEMLNNMD_02291	1.1e-176	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HEMLNNMD_02292	7e-267	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HEMLNNMD_02293	7.44e-91	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HEMLNNMD_02294	2.54e-51	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HEMLNNMD_02295	1.08e-80	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HEMLNNMD_02296	2.84e-143	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HEMLNNMD_02297	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HEMLNNMD_02298	3.01e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HEMLNNMD_02299	5.74e-48	ydaS	-	-	S	-	-	-	membrane
HEMLNNMD_02300	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HEMLNNMD_02301	2.26e-267	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEMLNNMD_02302	1.57e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
HEMLNNMD_02303	2.28e-108	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEMLNNMD_02305	6.64e-162	-	-	-	H	-	-	-	Methionine biosynthesis protein MetW
HEMLNNMD_02306	1.5e-157	-	-	-	S	-	-	-	Streptomycin biosynthesis protein StrF
HEMLNNMD_02307	5.3e-137	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEMLNNMD_02308	1.08e-52	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HEMLNNMD_02309	9.61e-215	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HEMLNNMD_02310	1.17e-190	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HEMLNNMD_02311	4.6e-173	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HEMLNNMD_02312	6.56e-39	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HEMLNNMD_02313	1.92e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEMLNNMD_02314	4.76e-164	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEMLNNMD_02315	6.58e-200	ywbI	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02316	9.02e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HEMLNNMD_02317	4.37e-142	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HEMLNNMD_02318	8.79e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HEMLNNMD_02319	9.07e-279	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HEMLNNMD_02320	5.06e-86	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HEMLNNMD_02321	1.23e-310	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEMLNNMD_02322	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEMLNNMD_02323	2.87e-205	gspA	-	-	M	-	-	-	General stress
HEMLNNMD_02325	2.16e-150	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HEMLNNMD_02326	7.25e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HEMLNNMD_02327	3.51e-18	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HEMLNNMD_02328	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_02329	2.45e-289	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HEMLNNMD_02330	1.96e-49	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_02331	2.84e-285	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEMLNNMD_02332	1.51e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEMLNNMD_02333	9.4e-317	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEMLNNMD_02334	3.97e-66	licA	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_02335	7.19e-314	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEMLNNMD_02336	3.67e-65	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HEMLNNMD_02337	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HEMLNNMD_02338	1.21e-140	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HEMLNNMD_02339	7.43e-217	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_02340	2.19e-227	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_02341	1.53e-212	cbrA3	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEMLNNMD_02342	4.16e-64	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HEMLNNMD_02343	6.72e-286	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HEMLNNMD_02344	3.25e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_02345	6.25e-63	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_02346	6.42e-299	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEMLNNMD_02347	0.0	ydhP	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEMLNNMD_02348	5.64e-134	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HEMLNNMD_02349	8.22e-33	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HEMLNNMD_02350	4.29e-227	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HEMLNNMD_02351	7.78e-260	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HEMLNNMD_02352	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEMLNNMD_02353	1.03e-237	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HEMLNNMD_02354	3.03e-315	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HEMLNNMD_02355	1.75e-191	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEMLNNMD_02356	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HEMLNNMD_02357	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HEMLNNMD_02358	5.93e-237	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HEMLNNMD_02359	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HEMLNNMD_02360	4.14e-283	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HEMLNNMD_02361	1.18e-191	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HEMLNNMD_02362	8.75e-260	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_02363	1.43e-196	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HEMLNNMD_02364	2.79e-189	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HEMLNNMD_02365	2.1e-117	yxkC	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HEMLNNMD_02366	8.55e-246	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HEMLNNMD_02367	1.57e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HEMLNNMD_02370	5.42e-105	yxjI	-	-	S	-	-	-	LURP-one-related
HEMLNNMD_02371	3.66e-274	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HEMLNNMD_02372	3.6e-188	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HEMLNNMD_02373	2.49e-262	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEMLNNMD_02374	6.34e-111	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HEMLNNMD_02375	3.23e-60	yxiS	-	-	-	-	-	-	-
HEMLNNMD_02376	3.04e-221	-	-	-	L	-	-	-	DNA synthesis involved in DNA repair
HEMLNNMD_02377	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEMLNNMD_02378	1.57e-281	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HEMLNNMD_02379	4.82e-176	bglS	-	-	M	-	-	-	licheninase activity
HEMLNNMD_02380	3e-183	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HEMLNNMD_02381	1.87e-186	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HEMLNNMD_02382	4.39e-64	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HEMLNNMD_02383	5.3e-238	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEMLNNMD_02384	7.16e-12	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HEMLNNMD_02387	1.13e-77	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HEMLNNMD_02388	4.2e-103	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
HEMLNNMD_02390	3.62e-28	-	-	-	-	-	-	-	-
HEMLNNMD_02391	4.4e-10	yxiJ	-	-	S	-	-	-	YxiJ-like protein
HEMLNNMD_02392	3.14e-140	-	-	-	-	-	-	-	-
HEMLNNMD_02393	8.87e-72	-	-	-	-	-	-	-	-
HEMLNNMD_02395	1.02e-85	yxiG	-	-	-	-	-	-	-
HEMLNNMD_02397	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HEMLNNMD_02398	2.04e-252	pelB	4.2.2.10, 4.2.2.2	-	G	ko:K01728,ko:K01732	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEMLNNMD_02399	8.65e-201	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HEMLNNMD_02400	2.44e-94	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HEMLNNMD_02401	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEMLNNMD_02402	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_02404	0.0	-	-	-	L	-	-	-	HKD family nuclease
HEMLNNMD_02405	2.8e-84	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HEMLNNMD_02406	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HEMLNNMD_02407	4.06e-102	hutP	-	-	K	ko:K09683	-	ko00000,ko03000	Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HEMLNNMD_02408	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HEMLNNMD_02409	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HEMLNNMD_02410	4.43e-290	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HEMLNNMD_02411	3.33e-216	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HEMLNNMD_02412	0.0	hutM	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEMLNNMD_02413	2.59e-295	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HEMLNNMD_02414	3.31e-264	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HEMLNNMD_02415	4.09e-145	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEMLNNMD_02416	9.22e-217	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HEMLNNMD_02417	1.23e-188	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HEMLNNMD_02420	7.69e-30	yxeE	-	-	-	-	-	-	-
HEMLNNMD_02422	9.67e-33	yxeD	-	-	-	-	-	-	-
HEMLNNMD_02424	7.03e-220	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HEMLNNMD_02425	1.85e-71	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HEMLNNMD_02426	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_02427	1.23e-177	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_02428	2.77e-224	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_02429	3.66e-156	yxdJ	-	-	T	ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_02430	3.8e-193	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HEMLNNMD_02431	1.15e-198	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HEMLNNMD_02432	1.72e-209	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HEMLNNMD_02433	1.94e-245	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HEMLNNMD_02434	2.37e-290	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HEMLNNMD_02435	8.24e-217	iolE	4.2.1.44	-	H	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HEMLNNMD_02436	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HEMLNNMD_02437	5.19e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HEMLNNMD_02438	2.24e-196	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HEMLNNMD_02439	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEMLNNMD_02440	1.75e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEMLNNMD_02441	5.36e-219	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HEMLNNMD_02442	2.13e-311	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEMLNNMD_02443	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HEMLNNMD_02444	1.56e-188	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEMLNNMD_02445	2.06e-129	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEMLNNMD_02446	1.57e-243	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_02447	1.04e-247	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HEMLNNMD_02448	4.37e-265	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HEMLNNMD_02449	5.9e-314	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HEMLNNMD_02450	1.05e-185	yxaL	-	-	S	-	-	-	PQQ-like domain
HEMLNNMD_02451	1.01e-75	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HEMLNNMD_02452	2.01e-66	arsR3	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEMLNNMD_02453	1.65e-250	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HEMLNNMD_02454	9.69e-78	yxaI	-	-	S	-	-	-	membrane protein domain
HEMLNNMD_02455	9.32e-154	-	-	-	E	-	-	-	Ring-cleavage extradiol dioxygenase
HEMLNNMD_02456	1.55e-134	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HEMLNNMD_02457	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HEMLNNMD_02458	4.01e-231	mrjp	-	-	G	-	-	-	Major royal jelly protein
HEMLNNMD_02459	6.23e-302	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HEMLNNMD_02460	3.35e-202	-	-	-	K	-	-	-	helix_turn_helix, Deoxyribose operon repressor
HEMLNNMD_02461	3.61e-96	-	-	-	K	-	-	-	Integron-associated effector binding protein
HEMLNNMD_02462	5.19e-97	yjhE	-	-	S	-	-	-	Phage tail protein
HEMLNNMD_02463	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HEMLNNMD_02464	1.87e-100	pucE	1.2.5.3	-	C	ko:K03518	-	ko00000,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HEMLNNMD_02465	9.98e-184	-	-	-	C	-	-	-	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HEMLNNMD_02466	0.0	-	-	-	C	-	-	-	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HEMLNNMD_02467	4.6e-108	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HEMLNNMD_02468	1.33e-213	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HEMLNNMD_02469	1.46e-205	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HEMLNNMD_02470	3.3e-27	-	-	-	-	-	-	-	-
HEMLNNMD_02471	0.0	-	-	-	L	-	-	-	AAA domain
HEMLNNMD_02473	3.7e-52	-	-	-	-	-	-	-	-
HEMLNNMD_02474	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEMLNNMD_02477	3.42e-259	yycP	-	-	-	-	-	-	-
HEMLNNMD_02478	1.08e-165	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEMLNNMD_02479	2.87e-161	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HEMLNNMD_02481	5.6e-66	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HEMLNNMD_02482	7.95e-127	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	COG0785 Cytochrome c biogenesis protein
HEMLNNMD_02484	2.13e-106	yycN	-	-	K	-	-	-	Acetyltransferase
HEMLNNMD_02486	7.15e-257	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HEMLNNMD_02487	8.84e-211	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HEMLNNMD_02488	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEMLNNMD_02489	8.65e-296	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HEMLNNMD_02490	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HEMLNNMD_02491	3.06e-250	-	-	-	S	-	-	-	Major Facilitator Superfamily
HEMLNNMD_02492	4.44e-309	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEMLNNMD_02493	3.35e-119	-	-	-	K	ko:K02483	-	ko00000,ko02022	PFAM response regulator receiver
HEMLNNMD_02494	1.71e-86	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HEMLNNMD_02495	4.99e-273	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEMLNNMD_02496	4.01e-191	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HEMLNNMD_02497	1.1e-191	yycI	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02498	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02499	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_02500	1.51e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_02505	4.45e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEMLNNMD_02506	1.06e-92	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEMLNNMD_02507	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HEMLNNMD_02508	9e-38	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HEMLNNMD_02510	3.6e-25	yycC	-	-	K	-	-	-	YycC-like protein
HEMLNNMD_02511	4.92e-274	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HEMLNNMD_02512	1.59e-243	-	-	-	S	-	-	-	Ecdysteroid kinase
HEMLNNMD_02513	4.08e-291	-	-	-	S	-	-	-	Carbamoyl-phosphate synthase L chain, ATP binding domain
HEMLNNMD_02514	8.3e-281	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HEMLNNMD_02515	4.17e-155	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HEMLNNMD_02516	1.11e-105	-	-	-	KLT	-	-	-	COG0515 Serine threonine protein kinase
HEMLNNMD_02517	2.25e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HEMLNNMD_02518	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HEMLNNMD_02519	4.48e-191	yybS	-	-	S	-	-	-	membrane
HEMLNNMD_02521	3.36e-105	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HEMLNNMD_02522	1.79e-84	yybR	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02523	4.01e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HEMLNNMD_02524	4.42e-192	ypaH	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEMLNNMD_02525	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HEMLNNMD_02526	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HEMLNNMD_02527	7.08e-145	-	-	-	K	-	-	-	FCD domain
HEMLNNMD_02529	5.12e-53	-	-	-	CP	-	-	-	Membrane
HEMLNNMD_02531	2.63e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HEMLNNMD_02532	2.66e-31	-	-	-	-	-	-	-	-
HEMLNNMD_02533	7.04e-24	ydcG	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HEMLNNMD_02535	5.34e-72	ypaA	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HEMLNNMD_02536	1.56e-144	ydgI	-	-	C	-	-	-	nitroreductase
HEMLNNMD_02537	5.14e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HEMLNNMD_02538	9.98e-190	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEMLNNMD_02539	7.24e-97	yybA	-	-	K	-	-	-	transcriptional
HEMLNNMD_02540	5.74e-92	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEMLNNMD_02541	7.1e-27	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEMLNNMD_02542	7.06e-129	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HEMLNNMD_02543	4.29e-38	-	-	-	-	-	-	-	-
HEMLNNMD_02544	2.63e-90	ynaF	-	-	-	-	-	-	-
HEMLNNMD_02545	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HEMLNNMD_02546	1.66e-193	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEMLNNMD_02547	2.4e-312	-	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
HEMLNNMD_02548	9.47e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEMLNNMD_02549	6.01e-217	ccpB	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02550	5.03e-179	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HEMLNNMD_02551	2.4e-114	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEMLNNMD_02552	5.31e-125	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HEMLNNMD_02553	1.11e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEMLNNMD_02554	1.37e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEMLNNMD_02555	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HEMLNNMD_02556	6.32e-253	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEMLNNMD_02557	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEMLNNMD_02558	1.82e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02559	1.9e-215	yyaD	-	-	S	-	-	-	Membrane
HEMLNNMD_02560	1.05e-95	yhhY	-	-	K	-	-	-	FR47-like protein
HEMLNNMD_02561	1.3e-139	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HEMLNNMD_02562	6.79e-188	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HEMLNNMD_02563	2.49e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HEMLNNMD_02564	1.1e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HEMLNNMD_02565	4.96e-159	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HEMLNNMD_02566	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEMLNNMD_02567	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEMLNNMD_02568	1.43e-136	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HEMLNNMD_02569	6.08e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEMLNNMD_02570	5.27e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEMLNNMD_02571	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEMLNNMD_02572	2.83e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEMLNNMD_02573	3.19e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HEMLNNMD_02574	1.07e-262	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEMLNNMD_02575	6.18e-52	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HEMLNNMD_02576	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEMLNNMD_02577	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEMLNNMD_02578	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_02581	1.41e-225	yaaC	-	-	S	-	-	-	YaaC-like Protein
HEMLNNMD_02582	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEMLNNMD_02583	2.81e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HEMLNNMD_02584	7.47e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HEMLNNMD_02585	1.93e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HEMLNNMD_02586	8.78e-283	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEMLNNMD_02587	1.36e-250	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HEMLNNMD_02589	6.92e-155	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HEMLNNMD_02590	3.32e-148	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HEMLNNMD_02591	3.6e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HEMLNNMD_02592	9.33e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HEMLNNMD_02593	2.78e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEMLNNMD_02594	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEMLNNMD_02595	6.9e-52	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEMLNNMD_02596	6e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEMLNNMD_02597	7.67e-43	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HEMLNNMD_02598	1.78e-47	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HEMLNNMD_02599	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_02602	1.5e-40	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HEMLNNMD_02603	3.02e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEMLNNMD_02604	3.13e-226	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HEMLNNMD_02605	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HEMLNNMD_02606	4.13e-140	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEMLNNMD_02607	5.03e-73	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02608	7.03e-93	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HEMLNNMD_02609	8.67e-230	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HEMLNNMD_02610	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HEMLNNMD_02611	2.53e-55	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HEMLNNMD_02612	1.56e-175	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HEMLNNMD_02613	1.35e-61	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HEMLNNMD_02614	2.81e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEMLNNMD_02615	6.14e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HEMLNNMD_02616	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEMLNNMD_02617	1.44e-182	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HEMLNNMD_02618	2.91e-287	yabE	-	-	T	-	-	-	protein conserved in bacteria
HEMLNNMD_02619	3.1e-125	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEMLNNMD_02620	6.62e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEMLNNMD_02621	1.46e-186	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HEMLNNMD_02622	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02623	7.31e-38	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HEMLNNMD_02624	1.84e-204	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEMLNNMD_02625	7.72e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HEMLNNMD_02626	7.5e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HEMLNNMD_02627	4.23e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HEMLNNMD_02628	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEMLNNMD_02629	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEMLNNMD_02630	1.4e-133	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HEMLNNMD_02631	4.99e-136	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEMLNNMD_02632	5.24e-53	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HEMLNNMD_02633	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEMLNNMD_02634	2.69e-117	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HEMLNNMD_02635	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HEMLNNMD_02636	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HEMLNNMD_02637	8.51e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HEMLNNMD_02638	5.47e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HEMLNNMD_02639	1.79e-129	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HEMLNNMD_02640	2.42e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HEMLNNMD_02641	3.54e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HEMLNNMD_02644	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HEMLNNMD_02645	8.92e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HEMLNNMD_02646	4.82e-229	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HEMLNNMD_02647	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEMLNNMD_02648	4.29e-119	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HEMLNNMD_02649	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEMLNNMD_02650	6.69e-177	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEMLNNMD_02651	7.52e-205	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEMLNNMD_02652	4.24e-193	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HEMLNNMD_02653	1.79e-216	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HEMLNNMD_02654	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HEMLNNMD_02655	6e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HEMLNNMD_02656	2.61e-190	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HEMLNNMD_02657	1.98e-197	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HEMLNNMD_02658	1.88e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEMLNNMD_02659	8.84e-113	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HEMLNNMD_02660	9.99e-39	yazB	-	-	K	-	-	-	transcriptional
HEMLNNMD_02661	8.33e-230	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEMLNNMD_02662	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HEMLNNMD_02663	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_02673	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_02674	2.14e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HEMLNNMD_02675	9.99e-78	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HEMLNNMD_02676	3.84e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HEMLNNMD_02677	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HEMLNNMD_02678	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEMLNNMD_02679	3.64e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HEMLNNMD_02680	1.85e-245	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HEMLNNMD_02681	2.89e-157	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HEMLNNMD_02682	1.23e-110	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEMLNNMD_02683	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEMLNNMD_02684	6.69e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HEMLNNMD_02685	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HEMLNNMD_02686	1.61e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEMLNNMD_02687	3.38e-171	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEMLNNMD_02688	1.92e-113	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HEMLNNMD_02689	4.65e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HEMLNNMD_02690	3.77e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEMLNNMD_02691	6.9e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HEMLNNMD_02692	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEMLNNMD_02693	5.01e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEMLNNMD_02694	6.68e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEMLNNMD_02695	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEMLNNMD_02696	1.46e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HEMLNNMD_02697	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEMLNNMD_02698	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEMLNNMD_02699	9.87e-45	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HEMLNNMD_02700	9.47e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEMLNNMD_02701	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEMLNNMD_02702	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEMLNNMD_02703	9.55e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEMLNNMD_02704	4.4e-221	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HEMLNNMD_02705	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HEMLNNMD_02706	1.02e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEMLNNMD_02707	3.68e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HEMLNNMD_02708	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEMLNNMD_02709	9.5e-201	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEMLNNMD_02710	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEMLNNMD_02711	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEMLNNMD_02712	1.69e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEMLNNMD_02713	1.38e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEMLNNMD_02714	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HEMLNNMD_02715	1.92e-51	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEMLNNMD_02716	1.04e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEMLNNMD_02717	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEMLNNMD_02718	2.58e-120	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEMLNNMD_02719	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEMLNNMD_02720	1.08e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEMLNNMD_02721	1.05e-119	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEMLNNMD_02722	2.38e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEMLNNMD_02723	4.54e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEMLNNMD_02724	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HEMLNNMD_02725	2.1e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HEMLNNMD_02726	1.82e-294	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEMLNNMD_02727	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEMLNNMD_02728	5.46e-181	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HEMLNNMD_02729	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEMLNNMD_02730	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HEMLNNMD_02731	1.54e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEMLNNMD_02732	4.61e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEMLNNMD_02733	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEMLNNMD_02734	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HEMLNNMD_02735	6.9e-196	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEMLNNMD_02736	1.83e-185	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEMLNNMD_02737	7.6e-176	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEMLNNMD_02738	3.42e-179	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEMLNNMD_02739	3.79e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEMLNNMD_02740	1.49e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HEMLNNMD_02741	4.46e-179	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HEMLNNMD_02743	2.28e-99	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HEMLNNMD_02744	4.3e-168	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HEMLNNMD_02745	1.6e-247	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEMLNNMD_02746	1.95e-102	gerD	-	-	-	ko:K06294	-	ko00000	-
HEMLNNMD_02747	1.25e-134	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HEMLNNMD_02748	1.14e-176	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HEMLNNMD_02749	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_02755	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_02756	2.1e-270	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
HEMLNNMD_02757	4.26e-312	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEMLNNMD_02758	1.75e-227	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
HEMLNNMD_02759	1.33e-254	-	1.1.1.14, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00008	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HEMLNNMD_02760	9.71e-282	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HEMLNNMD_02761	6.69e-183	ybaS	-	-	S	-	-	-	Na -dependent transporter
HEMLNNMD_02762	4.7e-128	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HEMLNNMD_02763	5.99e-224	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_02764	1.48e-224	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_02765	3.89e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HEMLNNMD_02766	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HEMLNNMD_02767	1.88e-292	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02768	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HEMLNNMD_02769	5.92e-298	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HEMLNNMD_02770	2.72e-299	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_02771	4.48e-206	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEMLNNMD_02772	3.4e-108	ybbJ	-	-	J	-	-	-	acetyltransferase
HEMLNNMD_02773	8.81e-98	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HEMLNNMD_02779	4.59e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_02780	1.7e-146	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HEMLNNMD_02781	9e-188	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEMLNNMD_02782	7.78e-292	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02783	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEMLNNMD_02784	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEMLNNMD_02785	1.73e-189	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HEMLNNMD_02786	1.16e-131	-	-	-	S	-	-	-	ABC-2 family transporter protein
HEMLNNMD_02787	5.62e-35	ybdN	-	-	-	-	-	-	-
HEMLNNMD_02788	2.57e-58	-	-	-	Q	-	-	-	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_02789	1.76e-162	-	-	-	T	ko:K11630	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_02790	5.45e-234	-	-	-	T	ko:K19168	-	ko00000,ko02048	Histidine kinase
HEMLNNMD_02791	3.8e-175	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_02792	4.42e-19	-	-	-	V	ko:K02004,ko:K11632	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_02793	0.0	-	-	-	V	ko:K02004,ko:K11632	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_02794	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEMLNNMD_02795	6.16e-199	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
HEMLNNMD_02796	1.42e-133	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HEMLNNMD_02797	3.67e-34	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HEMLNNMD_02798	2.57e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_02799	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEMLNNMD_02800	1.52e-118	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HEMLNNMD_02801	2.94e-231	-	-	-	T	-	-	-	COG4585 Signal transduction histidine kinase
HEMLNNMD_02802	5.5e-128	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HEMLNNMD_02803	1.06e-205	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HEMLNNMD_02804	1.17e-242	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HEMLNNMD_02805	4.65e-230	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HEMLNNMD_02806	3.22e-33	-	-	-	-	-	-	-	-
HEMLNNMD_02807	5.2e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4879)
HEMLNNMD_02808	2.48e-52	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HEMLNNMD_02809	1.04e-136	yqeB	-	-	-	-	-	-	-
HEMLNNMD_02810	6.22e-52	ybyB	-	-	-	-	-	-	-
HEMLNNMD_02811	0.0	ybeC	-	-	E	-	-	-	amino acid
HEMLNNMD_02812	3.11e-23	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HEMLNNMD_02813	3.73e-209	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HEMLNNMD_02814	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HEMLNNMD_02815	2.47e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HEMLNNMD_02816	6.44e-261	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HEMLNNMD_02818	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HEMLNNMD_02820	1.34e-104	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_02821	3.98e-237	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HEMLNNMD_02822	2.85e-265	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEMLNNMD_02823	9.04e-120	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEMLNNMD_02824	3.37e-110	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HEMLNNMD_02825	4.85e-191	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HEMLNNMD_02826	4.65e-50	ybfN	-	-	-	-	-	-	-
HEMLNNMD_02827	1.78e-239	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HEMLNNMD_02828	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
HEMLNNMD_02829	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
HEMLNNMD_02830	5.27e-266	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEMLNNMD_02831	1.04e-248	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HEMLNNMD_02832	8.9e-317	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HEMLNNMD_02833	3.81e-226	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HEMLNNMD_02834	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HEMLNNMD_02835	8.78e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HEMLNNMD_02836	9.19e-265	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_02837	2.43e-197	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HEMLNNMD_02838	4.88e-160	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HEMLNNMD_02839	3.3e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HEMLNNMD_02840	8.64e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEMLNNMD_02841	2.72e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HEMLNNMD_02842	8.39e-233	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEMLNNMD_02843	3.27e-83	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HEMLNNMD_02844	3.92e-76	ydfQ	-	-	CO	-	-	-	Thioredoxin
HEMLNNMD_02845	4.68e-82	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HEMLNNMD_02846	3.67e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HEMLNNMD_02847	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HEMLNNMD_02848	5.03e-35	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEMLNNMD_02849	8.7e-157	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEMLNNMD_02850	1.4e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HEMLNNMD_02851	1.65e-248	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HEMLNNMD_02852	2.09e-305	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HEMLNNMD_02853	3.35e-125	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HEMLNNMD_02854	1.44e-141	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HEMLNNMD_02855	7.31e-247	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HEMLNNMD_02856	2.62e-210	yccK	-	-	C	-	-	-	Aldo keto reductase
HEMLNNMD_02857	1.8e-207	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HEMLNNMD_02858	3.86e-222	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_02859	9.14e-317	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_02860	1.86e-114	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HEMLNNMD_02861	3.74e-221	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HEMLNNMD_02862	6.52e-174	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HEMLNNMD_02863	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEMLNNMD_02864	3.69e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
HEMLNNMD_02865	9.24e-63	-	-	-	K	-	-	-	Virulence activator alpha C-term
HEMLNNMD_02866	1.35e-212	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HEMLNNMD_02867	1.15e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HEMLNNMD_02868	1.38e-173	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HEMLNNMD_02869	1.06e-231	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_02870	9.56e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HEMLNNMD_02871	7.32e-136	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HEMLNNMD_02872	1.94e-135	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HEMLNNMD_02873	4.28e-178	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HEMLNNMD_02874	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HEMLNNMD_02875	1.36e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HEMLNNMD_02876	3.23e-270	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HEMLNNMD_02878	2.12e-291	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HEMLNNMD_02879	7.02e-185	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HEMLNNMD_02880	4.54e-207	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HEMLNNMD_02881	3.87e-262	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HEMLNNMD_02882	4.05e-287	ycgA	-	-	S	-	-	-	Membrane
HEMLNNMD_02883	1.04e-53	ycgB	-	-	-	-	-	-	-
HEMLNNMD_02884	2.85e-15	-	-	-	S	-	-	-	RDD family
HEMLNNMD_02885	8.99e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HEMLNNMD_02886	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
HEMLNNMD_02887	3.16e-97	ycgE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_02888	3.18e-147	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
HEMLNNMD_02889	4.7e-189	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HEMLNNMD_02890	3.93e-306	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HEMLNNMD_02891	6.25e-144	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HEMLNNMD_02892	1.44e-188	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEMLNNMD_02893	1.76e-125	-	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
HEMLNNMD_02894	1.66e-288	-	-	-	G	ko:K08191,ko:K08194	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_02895	2.04e-134	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HEMLNNMD_02896	1.83e-230	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HEMLNNMD_02897	2.89e-178	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HEMLNNMD_02898	2.64e-214	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HEMLNNMD_02899	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HEMLNNMD_02900	1.05e-309	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEMLNNMD_02901	1.86e-286	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HEMLNNMD_02902	1.07e-238	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HEMLNNMD_02903	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HEMLNNMD_02904	2.34e-72	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HEMLNNMD_02905	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HEMLNNMD_02906	1.8e-50	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HEMLNNMD_02907	4.18e-282	yciC	-	-	S	-	-	-	GTPases (G3E family)
HEMLNNMD_02908	6.16e-277	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEMLNNMD_02909	3.65e-94	yckC	-	-	S	-	-	-	membrane
HEMLNNMD_02910	7.52e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HEMLNNMD_02911	0.0	yckE	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEMLNNMD_02912	7.34e-86	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HEMLNNMD_02913	2.67e-101	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEMLNNMD_02914	1.22e-121	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HEMLNNMD_02915	2.27e-132	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HEMLNNMD_02916	2.89e-84	hxlR	-	-	K	-	-	-	transcriptional
HEMLNNMD_02917	1.24e-223	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_02918	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_02919	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEMLNNMD_02920	7.03e-45	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEMLNNMD_02921	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HEMLNNMD_02922	1.34e-174	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HEMLNNMD_02923	2.48e-315	-	-	-	E	-	-	-	Aminotransferase class I and II
HEMLNNMD_02924	4.14e-155	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HEMLNNMD_02925	1.59e-137	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HEMLNNMD_02926	9.29e-168	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HEMLNNMD_02927	5.85e-152	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEMLNNMD_02928	1.1e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HEMLNNMD_02929	2.49e-198	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HEMLNNMD_02930	3.44e-130	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HEMLNNMD_02931	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HEMLNNMD_02932	6.46e-49	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HEMLNNMD_02933	8.93e-96	yclD	-	-	-	-	-	-	-
HEMLNNMD_02934	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HEMLNNMD_02935	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HEMLNNMD_02937	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
HEMLNNMD_02938	6.53e-290	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HEMLNNMD_02939	4.89e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HEMLNNMD_02940	8.5e-316	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HEMLNNMD_02941	2.47e-117	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEMLNNMD_02942	2.03e-179	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HEMLNNMD_02943	8.59e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HEMLNNMD_02944	2.66e-168	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_02945	7.36e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HEMLNNMD_02946	7e-303	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HEMLNNMD_02947	1.23e-153	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HEMLNNMD_02948	8.82e-28	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HEMLNNMD_02949	1.75e-246	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HEMLNNMD_02950	8.72e-163	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEMLNNMD_02951	0.0	yclK	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HEMLNNMD_02952	7.01e-96	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HEMLNNMD_02955	4.17e-314	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HEMLNNMD_02956	1.06e-208	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_02957	1.4e-212	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEMLNNMD_02958	6.31e-173	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_02959	2.89e-221	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HEMLNNMD_02960	1.97e-311	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HEMLNNMD_02961	4.78e-192	ycnC	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02962	2.68e-172	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Nitroreductase family
HEMLNNMD_02963	2.79e-59	ycnE	-	-	S	-	-	-	Monooxygenase
HEMLNNMD_02964	1.08e-67	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HEMLNNMD_02965	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEMLNNMD_02966	2.59e-279	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEMLNNMD_02967	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEMLNNMD_02968	3.93e-189	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HEMLNNMD_02969	7.4e-181	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_02970	1.4e-122	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_02971	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HEMLNNMD_02972	4.78e-135	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEMLNNMD_02973	6.5e-71	-	-	-	-	-	-	-	-
HEMLNNMD_02974	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HEMLNNMD_02975	1.96e-93	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HEMLNNMD_02976	1.38e-255	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HEMLNNMD_02977	4.09e-78	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HEMLNNMD_02979	2.59e-175	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEMLNNMD_02980	1e-170	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HEMLNNMD_02981	3.46e-267	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HEMLNNMD_02982	1.68e-183	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HEMLNNMD_02983	1.18e-168	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HEMLNNMD_02984	8.55e-225	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HEMLNNMD_02985	3.33e-162	kipR	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_02986	4.64e-142	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HEMLNNMD_02988	3.88e-71	yczJ	-	-	S	-	-	-	biosynthesis
HEMLNNMD_02989	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HEMLNNMD_02990	7.28e-212	ycsN	-	-	S	-	-	-	Oxidoreductase
HEMLNNMD_02991	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HEMLNNMD_02992	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HEMLNNMD_02993	5.81e-200	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_02994	7.59e-123	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HEMLNNMD_02995	3.16e-137	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEMLNNMD_02996	4.32e-100	ydaG	-	-	S	-	-	-	general stress protein
HEMLNNMD_02997	9.89e-174	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HEMLNNMD_02998	1.09e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HEMLNNMD_02999	7.9e-32	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HEMLNNMD_03000	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEMLNNMD_03001	2.79e-193	ydaJ	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
HEMLNNMD_03002	2.35e-183	ydaK	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HEMLNNMD_03003	7.07e-195	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HEMLNNMD_03004	2.87e-157	ydaL	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2334)
HEMLNNMD_03005	4.35e-301	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
HEMLNNMD_03006	0.0	ydaN	-	-	S	-	-	-	Bacterial cellulose synthase subunit
HEMLNNMD_03007	0.0	ydaO	-	-	E	-	-	-	amino acid
HEMLNNMD_03008	2.6e-45	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEMLNNMD_03009	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HEMLNNMD_03010	5.03e-80	-	-	-	K	-	-	-	acetyltransferase
HEMLNNMD_03011	7.58e-111	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HEMLNNMD_03012	1.3e-84	-	-	-	-	-	-	-	-
HEMLNNMD_03013	1.07e-263	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
HEMLNNMD_03016	2.14e-53	-	-	-	-	-	-	-	-
HEMLNNMD_03017	1.03e-285	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HEMLNNMD_03019	1.95e-45	ydaT	-	-	-	-	-	-	-
HEMLNNMD_03020	1.12e-95	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HEMLNNMD_03021	2.76e-69	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HEMLNNMD_03022	6.18e-172	ydbA	-	-	P	-	-	-	EcsC protein family
HEMLNNMD_03023	5.1e-09	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HEMLNNMD_03024	1.04e-75	ydbB	-	-	G	-	-	-	Cupin domain
HEMLNNMD_03025	4.64e-76	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HEMLNNMD_03026	2.61e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HEMLNNMD_03027	7.93e-248	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEMLNNMD_03028	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEMLNNMD_03029	1.87e-146	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HEMLNNMD_03030	1.07e-284	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEMLNNMD_03031	1.85e-225	ydbI	-	-	S	-	-	-	AI-2E family transporter
HEMLNNMD_03032	4.4e-217	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_03033	7.81e-164	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEMLNNMD_03034	1.32e-69	ydbL	-	-	-	-	-	-	-
HEMLNNMD_03035	2.96e-36	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HEMLNNMD_03036	8.48e-199	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HEMLNNMD_03037	2.36e-17	-	-	-	S	-	-	-	Fur-regulated basic protein B
HEMLNNMD_03038	6.11e-15	-	-	-	S	-	-	-	Fur-regulated basic protein A
HEMLNNMD_03039	9.92e-161	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEMLNNMD_03040	2.25e-74	ydbP	-	-	CO	-	-	-	Thioredoxin
HEMLNNMD_03041	2.07e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HEMLNNMD_03042	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEMLNNMD_03043	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEMLNNMD_03044	1.11e-91	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HEMLNNMD_03045	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HEMLNNMD_03046	3.32e-135	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HEMLNNMD_03047	9.63e-70	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEMLNNMD_03048	1.18e-230	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HEMLNNMD_03049	7.09e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEMLNNMD_03050	6.68e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HEMLNNMD_03051	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HEMLNNMD_03052	9.89e-176	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HEMLNNMD_03053	1.09e-75	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HEMLNNMD_03054	9.55e-44	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEMLNNMD_03055	1.55e-22	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HEMLNNMD_03056	1.92e-190	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HEMLNNMD_03057	3.28e-69	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HEMLNNMD_03058	5.84e-110	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HEMLNNMD_03059	2.67e-179	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_03060	1.07e-136	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HEMLNNMD_03061	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HEMLNNMD_03062	1.78e-21	-	-	-	-	-	-	-	-
HEMLNNMD_03063	5.5e-103	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HEMLNNMD_03071	1.06e-176	-	-	-	I	ko:K01066	-	ko00000,ko01000	esterase
HEMLNNMD_03072	3.54e-62	ohrB	-	-	O	-	-	-	OsmC-like protein
HEMLNNMD_03073	7.77e-65	ohrR	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03076	1.21e-215	ybfA	-	-	K	-	-	-	FR47-like protein
HEMLNNMD_03077	1.64e-287	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_03078	1.77e-239	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HEMLNNMD_03079	1.13e-26	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HEMLNNMD_03081	2.05e-100	-	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03082	7.03e-123	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HEMLNNMD_03083	3.05e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HEMLNNMD_03084	1.9e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF3888)
HEMLNNMD_03085	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
HEMLNNMD_03086	5.62e-97	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HEMLNNMD_03087	3.88e-74	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HEMLNNMD_03088	1.22e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
HEMLNNMD_03089	6.49e-65	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HEMLNNMD_03090	6.94e-301	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEMLNNMD_03091	4.16e-240	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HEMLNNMD_03092	8.2e-219	-	-	-	S	-	-	-	Patatin-like phospholipase
HEMLNNMD_03094	0.0	yvdP	-	-	C	-	-	-	COG0277 FAD FMN-containing dehydrogenases
HEMLNNMD_03095	5.25e-90	-	-	-	E	ko:K07032	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEMLNNMD_03096	7.27e-197	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HEMLNNMD_03097	1.34e-200	-	-	-	S	-	-	-	SNARE associated Golgi protein
HEMLNNMD_03098	3.99e-123	yrkC	-	-	G	-	-	-	Cupin domain
HEMLNNMD_03099	3.15e-109	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HEMLNNMD_03100	6.02e-187	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HEMLNNMD_03102	2.65e-133	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HEMLNNMD_03103	1.07e-79	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
HEMLNNMD_03104	7.14e-63	ydeH	-	-	-	-	-	-	-
HEMLNNMD_03105	1e-203	-	-	-	S	-	-	-	Sodium Bile acid symporter family
HEMLNNMD_03106	1.32e-250	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HEMLNNMD_03107	1.3e-80	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HEMLNNMD_03108	1.28e-277	nhaC_1	-	-	C	-	-	-	antiporter
HEMLNNMD_03109	3.85e-313	-	-	-	K	ko:K00375	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HEMLNNMD_03110	1.28e-131	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_03112	3.67e-235	ydeR	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HEMLNNMD_03113	4.29e-129	ydeS	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03114	1.42e-190	ydeK	-	-	EG	-	-	-	-transporter
HEMLNNMD_03115	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEMLNNMD_03116	1.16e-62	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HEMLNNMD_03117	1.45e-34	yraE	-	-	-	ko:K06440	-	ko00000	-
HEMLNNMD_03118	3.98e-278	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HEMLNNMD_03119	4.76e-84	yraF	-	-	M	-	-	-	Spore coat protein
HEMLNNMD_03120	4.73e-47	yraG	-	-	-	ko:K06440	-	ko00000	-
HEMLNNMD_03121	6.07e-165	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
HEMLNNMD_03122	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HEMLNNMD_03123	3.55e-116	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HEMLNNMD_03124	1.43e-190	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEMLNNMD_03125	1.89e-248	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
HEMLNNMD_03126	6.89e-262	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HEMLNNMD_03127	9.87e-282	fabF_1	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEMLNNMD_03128	8.75e-198	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_03129	1.05e-156	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEMLNNMD_03130	5.49e-102	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HEMLNNMD_03131	2.96e-177	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HEMLNNMD_03132	1.84e-184	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HEMLNNMD_03133	2.71e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HEMLNNMD_03134	3.02e-134	-	3.1.1.24	-	S	ko:K01055	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Alpha/beta hydrolase family
HEMLNNMD_03135	5.93e-212	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Isocitrate/isopropylmalate dehydrogenase
HEMLNNMD_03136	1.3e-144	ydhC	-	-	K	-	-	-	FCD
HEMLNNMD_03137	1.44e-276	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEMLNNMD_03139	8.03e-311	pbpE	-	-	V	-	-	-	Beta-lactamase
HEMLNNMD_03141	6.82e-125	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HEMLNNMD_03142	1.76e-244	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HEMLNNMD_03143	2.21e-166	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HEMLNNMD_03144	3.9e-146	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HEMLNNMD_03145	1.15e-265	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HEMLNNMD_03146	2.88e-63	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HEMLNNMD_03147	4.14e-63	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HEMLNNMD_03148	5.78e-133	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03149	0.0	ybeC	-	-	E	-	-	-	amino acid
HEMLNNMD_03150	1.65e-209	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HEMLNNMD_03151	7.76e-108	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HEMLNNMD_03152	2.29e-227	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HEMLNNMD_03153	2.26e-70	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEMLNNMD_03154	6.9e-214	iolT	-	-	U	ko:K02100,ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEMLNNMD_03157	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_03160	1.21e-218	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HEMLNNMD_03161	5.87e-109	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HEMLNNMD_03162	2.69e-158	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HEMLNNMD_03163	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HEMLNNMD_03164	3.17e-238	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEMLNNMD_03165	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HEMLNNMD_03166	5.96e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEMLNNMD_03167	1.51e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEMLNNMD_03168	1.72e-29	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HEMLNNMD_03169	7.81e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEMLNNMD_03170	1.11e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HEMLNNMD_03171	9.24e-162	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HEMLNNMD_03172	1.24e-57	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEMLNNMD_03173	4.84e-18	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEMLNNMD_03174	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEMLNNMD_03175	6.22e-183	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEMLNNMD_03176	3.83e-27	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HEMLNNMD_03177	6.55e-45	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HEMLNNMD_03178	4.05e-19	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_03179	3.24e-12	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_03180	9.71e-48	-	-	-	-	-	-	-	-
HEMLNNMD_03181	1.36e-50	-	-	-	S	-	-	-	DNA binding
HEMLNNMD_03182	3.81e-109	-	-	-	-	-	-	-	-
HEMLNNMD_03188	1.21e-189	yqaJ	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HEMLNNMD_03189	3.84e-166	recT	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HEMLNNMD_03190	1.62e-36	yqaL	-	-	L	-	-	-	DnaD domain protein
HEMLNNMD_03191	7.64e-153	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
HEMLNNMD_03193	1.36e-79	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
HEMLNNMD_03195	1.16e-23	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEMLNNMD_03197	2.51e-07	-	-	-	S	-	-	-	YopX protein
HEMLNNMD_03200	2.54e-133	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HEMLNNMD_03201	5.95e-92	-	-	-	-	-	-	-	-
HEMLNNMD_03203	8.76e-75	-	-	-	-	-	-	-	-
HEMLNNMD_03205	8.85e-66	-	-	-	S	-	-	-	dUTPase
HEMLNNMD_03211	3.72e-57	-	-	-	-	-	-	-	-
HEMLNNMD_03213	9.39e-78	-	-	-	E	-	-	-	Glyoxalase-like domain
HEMLNNMD_03214	3.4e-87	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEMLNNMD_03216	1.74e-17	-	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03219	1.02e-24	yqaS	-	-	L	-	-	-	DNA packaging
HEMLNNMD_03220	1.47e-82	yqaS	-	-	L	-	-	-	DNA packaging
HEMLNNMD_03221	8.3e-235	-	-	-	S	-	-	-	Terminase-like family
HEMLNNMD_03222	3.27e-247	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HEMLNNMD_03223	8.58e-114	-	-	-	S	-	-	-	Phage Mu protein F like protein
HEMLNNMD_03224	1.22e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HEMLNNMD_03225	9.37e-184	-	-	-	S	-	-	-	Phage capsid family
HEMLNNMD_03226	1.26e-05	-	-	-	-	-	-	-	-
HEMLNNMD_03228	1.5e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEMLNNMD_03229	8.56e-37	-	-	-	S	-	-	-	Phage head-tail joining protein
HEMLNNMD_03230	9.08e-50	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEMLNNMD_03231	1.4e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3168)
HEMLNNMD_03232	1.05e-42	-	-	-	S	-	-	-	Phage tail tube protein
HEMLNNMD_03233	9.39e-12	chiA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 18 family
HEMLNNMD_03236	2.62e-185	-	-	-	-	-	-	-	-
HEMLNNMD_03238	7.1e-165	-	-	-	L	-	-	-	Phage minor structural protein
HEMLNNMD_03243	7.85e-77	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HEMLNNMD_03244	7e-156	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEMLNNMD_03247	0.0	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
HEMLNNMD_03249	2.21e-81	-	-	-	-	-	-	-	-
HEMLNNMD_03250	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HEMLNNMD_03251	2.29e-253	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HEMLNNMD_03252	1.1e-311	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HEMLNNMD_03253	3.9e-217	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HEMLNNMD_03254	1.03e-40	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HEMLNNMD_03255	4.36e-143	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HEMLNNMD_03256	6.45e-222	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEMLNNMD_03257	3.8e-154	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HEMLNNMD_03258	3.8e-199	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HEMLNNMD_03259	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HEMLNNMD_03260	6.72e-185	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HEMLNNMD_03261	6.25e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_03262	9.22e-245	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HEMLNNMD_03263	7.91e-83	ydjM	-	-	M	-	-	-	Lytic transglycolase
HEMLNNMD_03264	1.51e-189	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HEMLNNMD_03266	1.17e-46	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HEMLNNMD_03267	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HEMLNNMD_03268	2.56e-307	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HEMLNNMD_03269	7.66e-193	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEMLNNMD_03270	7.99e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HEMLNNMD_03271	2.11e-256	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HEMLNNMD_03272	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HEMLNNMD_03273	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HEMLNNMD_03274	3.03e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_03275	7.81e-316	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HEMLNNMD_03276	1.01e-268	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HEMLNNMD_03277	1.2e-165	yebC	-	-	M	-	-	-	Membrane
HEMLNNMD_03279	7.62e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HEMLNNMD_03280	7.68e-39	yebG	-	-	S	-	-	-	NETI protein
HEMLNNMD_03281	1.87e-107	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEMLNNMD_03282	1.99e-281	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEMLNNMD_03283	1.05e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEMLNNMD_03284	4.62e-164	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HEMLNNMD_03285	8.96e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEMLNNMD_03286	7.47e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEMLNNMD_03287	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEMLNNMD_03288	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEMLNNMD_03289	5.96e-241	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HEMLNNMD_03290	3.89e-132	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEMLNNMD_03291	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HEMLNNMD_03292	2.12e-293	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HEMLNNMD_03293	5e-81	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HEMLNNMD_03294	9.21e-172	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HEMLNNMD_03295	2.32e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HEMLNNMD_03296	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HEMLNNMD_03297	1.85e-241	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HEMLNNMD_03298	2.03e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_03299	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HEMLNNMD_03300	5.04e-163	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HEMLNNMD_03301	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HEMLNNMD_03302	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEMLNNMD_03303	1.59e-285	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HEMLNNMD_03304	1.83e-232	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HEMLNNMD_03305	7.98e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HEMLNNMD_03306	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEMLNNMD_03307	1.81e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEMLNNMD_03308	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEMLNNMD_03309	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEMLNNMD_03310	3.62e-142	yerO	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03311	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEMLNNMD_03312	8.56e-217	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HEMLNNMD_03313	4.62e-314	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEMLNNMD_03314	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
HEMLNNMD_03315	5.95e-95	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
HEMLNNMD_03316	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
HEMLNNMD_03317	2.2e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1643)
HEMLNNMD_03318	1.53e-102	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEMLNNMD_03319	1.14e-105	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HEMLNNMD_03320	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HEMLNNMD_03321	4.43e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HEMLNNMD_03323	3.96e-138	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HEMLNNMD_03324	1.32e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HEMLNNMD_03325	1.34e-60	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HEMLNNMD_03326	4.26e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HEMLNNMD_03327	1.88e-112	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HEMLNNMD_03329	1.26e-147	yetF	-	-	S	-	-	-	membrane
HEMLNNMD_03330	4.35e-70	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HEMLNNMD_03331	4.96e-83	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEMLNNMD_03332	3.41e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEMLNNMD_03333	9.52e-30	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HEMLNNMD_03334	1.5e-72	-	-	-	H	-	-	-	riboflavin kinase activity
HEMLNNMD_03335	5.15e-135	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HEMLNNMD_03336	1.3e-111	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_03337	2.87e-127	yetM	-	-	CH	-	-	-	FAD binding domain
HEMLNNMD_03338	1.02e-99	yetM	-	-	CH	-	-	-	FAD binding domain
HEMLNNMD_03339	7.97e-251	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HEMLNNMD_03340	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HEMLNNMD_03342	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HEMLNNMD_03343	1.7e-187	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HEMLNNMD_03344	6.8e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HEMLNNMD_03345	2.78e-222	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HEMLNNMD_03346	1.88e-271	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HEMLNNMD_03347	1.62e-228	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HEMLNNMD_03348	4.78e-272	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_03349	2.1e-306	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HEMLNNMD_03350	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HEMLNNMD_03351	4.34e-148	yfmS	-	-	NT	-	-	-	chemotaxis protein
HEMLNNMD_03352	1.93e-211	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HEMLNNMD_03353	7.17e-258	-	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEMLNNMD_03354	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEMLNNMD_03355	8.36e-89	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HEMLNNMD_03356	4.34e-249	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HEMLNNMD_03357	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HEMLNNMD_03358	3.3e-260	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HEMLNNMD_03359	9.68e-231	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HEMLNNMD_03360	1.39e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HEMLNNMD_03361	4.9e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HEMLNNMD_03362	6.48e-127	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEMLNNMD_03363	3.01e-106	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HEMLNNMD_03364	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HEMLNNMD_03369	7.54e-07	-	-	-	S	-	-	-	domain, Protein
HEMLNNMD_03371	0.0	ywpD	-	-	T	-	-	-	Histidine kinase
HEMLNNMD_03372	2.26e-189	M1-574	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEMLNNMD_03373	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HEMLNNMD_03374	0.0	-	-	-	M	-	-	-	cell wall anchor domain
HEMLNNMD_03375	4.77e-105	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HEMLNNMD_03376	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HEMLNNMD_03377	2.02e-147	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HEMLNNMD_03378	2.35e-218	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HEMLNNMD_03379	1.06e-282	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HEMLNNMD_03380	1.61e-181	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HEMLNNMD_03381	9.97e-269	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HEMLNNMD_03382	4.43e-56	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HEMLNNMD_03383	2.2e-149	yflK	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_03384	5.84e-21	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HEMLNNMD_03385	5.69e-26	yflI	-	-	-	-	-	-	-
HEMLNNMD_03386	1.38e-65	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HEMLNNMD_03387	1.05e-174	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HEMLNNMD_03388	2.4e-313	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HEMLNNMD_03389	1.86e-95	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HEMLNNMD_03390	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HEMLNNMD_03391	6.69e-81	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HEMLNNMD_03392	2.79e-102	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HEMLNNMD_03393	6.73e-51	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HEMLNNMD_03394	1.85e-53	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HEMLNNMD_03395	3.52e-310	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_03396	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HEMLNNMD_03397	1.18e-161	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HEMLNNMD_03398	4.67e-155	frp	-	-	C	-	-	-	nitroreductase
HEMLNNMD_03399	6.13e-158	yibF	-	-	S	-	-	-	YibE/F-like protein
HEMLNNMD_03400	2.44e-238	yibE	-	-	S	-	-	-	YibE/F-like protein
HEMLNNMD_03401	0.0	cpdB	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
HEMLNNMD_03402	7.82e-118	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HEMLNNMD_03403	4.44e-230	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HEMLNNMD_03404	3.96e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEMLNNMD_03405	3.47e-166	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEMLNNMD_03406	2.03e-244	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_03407	1.66e-38	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HEMLNNMD_03408	6.36e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEMLNNMD_03409	4.68e-64	yfkI	-	-	S	-	-	-	gas vesicle protein
HEMLNNMD_03410	7.59e-183	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HEMLNNMD_03411	8.58e-271	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_03412	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HEMLNNMD_03413	1.23e-180	yfkD	-	-	S	-	-	-	YfkD-like protein
HEMLNNMD_03414	9.64e-185	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HEMLNNMD_03415	3.82e-278	yfkA	-	-	S	-	-	-	YfkB-like domain
HEMLNNMD_03416	7.99e-37	yfjT	-	-	-	-	-	-	-
HEMLNNMD_03417	1.36e-68	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HEMLNNMD_03418	4.85e-89	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HEMLNNMD_03419	3.56e-180	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HEMLNNMD_03421	5.27e-235	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HEMLNNMD_03422	4.16e-200	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HEMLNNMD_03424	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEMLNNMD_03426	1.36e-71	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase
HEMLNNMD_03427	2.38e-81	-	-	-	S	-	-	-	Phosphotransferase enzyme family
HEMLNNMD_03428	1.44e-93	-	-	-	-	-	-	-	-
HEMLNNMD_03430	1.11e-87	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HEMLNNMD_03431	4.73e-72	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HEMLNNMD_03432	4.6e-95	drrA	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HEMLNNMD_03433	7.49e-87	-	-	-	CP	-	-	-	ABC-2 family transporter protein
HEMLNNMD_03434	2.32e-165	-	-	-	C	-	-	-	alcohol dehydrogenase
HEMLNNMD_03435	1.06e-59	-	-	-	S	-	-	-	YfzA-like protein
HEMLNNMD_03436	1.93e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEMLNNMD_03437	2.86e-102	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HEMLNNMD_03438	2.08e-239	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HEMLNNMD_03439	5.46e-235	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HEMLNNMD_03440	7.49e-263	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEMLNNMD_03441	6.01e-305	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HEMLNNMD_03442	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HEMLNNMD_03443	3.29e-22	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HEMLNNMD_03444	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HEMLNNMD_03445	1.28e-177	glvR	-	-	F	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HEMLNNMD_03446	5.09e-192	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_03447	4.12e-139	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_03448	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
HEMLNNMD_03449	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HEMLNNMD_03450	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEMLNNMD_03451	7.86e-82	yfiD3	-	-	S	-	-	-	DoxX
HEMLNNMD_03452	5.43e-195	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HEMLNNMD_03453	3.16e-209	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HEMLNNMD_03454	1e-119	padR	-	-	K	-	-	-	transcriptional
HEMLNNMD_03455	9.06e-129	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEMLNNMD_03456	1.96e-222	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HEMLNNMD_03457	1.37e-59	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HEMLNNMD_03458	2.9e-122	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HEMLNNMD_03459	0.0	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HEMLNNMD_03460	8.25e-101	yfiV	-	-	K	-	-	-	transcriptional
HEMLNNMD_03461	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEMLNNMD_03462	1.22e-191	yfhB	-	-	S	-	-	-	PhzF family
HEMLNNMD_03463	6.23e-133	yfhC	-	-	C	-	-	-	nitroreductase
HEMLNNMD_03464	6.01e-33	yfhD	-	-	S	-	-	-	YfhD-like protein
HEMLNNMD_03466	4.54e-210	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HEMLNNMD_03467	1.95e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HEMLNNMD_03468	4.6e-60	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HEMLNNMD_03469	2.74e-266	yfhI	-	-	EGP	-	-	-	-transporter
HEMLNNMD_03471	3.43e-207	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HEMLNNMD_03472	1.49e-58	yfhJ	-	-	S	-	-	-	WVELL protein
HEMLNNMD_03473	1.14e-112	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HEMLNNMD_03474	5.95e-50	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HEMLNNMD_03475	7.32e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HEMLNNMD_03476	4.51e-235	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEMLNNMD_03477	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HEMLNNMD_03478	2.13e-229	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HEMLNNMD_03479	7.75e-258	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HEMLNNMD_03480	4.23e-49	yfhS	-	-	-	-	-	-	-
HEMLNNMD_03481	1.73e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_03482	9.58e-06	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HEMLNNMD_03483	1.4e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HEMLNNMD_03484	2.32e-135	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HEMLNNMD_03485	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HEMLNNMD_03486	1.76e-237	ygaE	-	-	S	-	-	-	Membrane
HEMLNNMD_03487	3.13e-310	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HEMLNNMD_03488	3.83e-109	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HEMLNNMD_03489	6.8e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HEMLNNMD_03490	1.1e-73	ygzB	-	-	S	-	-	-	UPF0295 protein
HEMLNNMD_03491	2.08e-208	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HEMLNNMD_03492	9.3e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HEMLNNMD_03508	2.7e-125	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HEMLNNMD_03511	1.21e-46	-	-	-	-	-	-	-	-
HEMLNNMD_03512	2.46e-22	-	-	-	-	-	-	-	-
HEMLNNMD_03515	5.36e-81	-	-	-	-	-	-	-	-
HEMLNNMD_03517	1.89e-140	-	-	-	L	ko:K02315	-	ko00000,ko03032	DNA-dependent DNA replication
HEMLNNMD_03518	6.73e-45	-	-	-	S	-	-	-	Protein of unknown function (DUF2493)
HEMLNNMD_03521	2.28e-176	-	-	-	L	-	-	-	DnaB-like helicase C terminal domain
HEMLNNMD_03522	2.24e-170	-	-	-	L	-	-	-	Toprim-like
HEMLNNMD_03523	2.97e-10	-	-	-	S	-	-	-	Cro/C1-type HTH DNA-binding domain
HEMLNNMD_03530	8.57e-59	-	-	-	-	-	-	-	-
HEMLNNMD_03531	1.52e-63	-	-	-	-	-	-	-	-
HEMLNNMD_03532	4.36e-33	-	-	-	-	-	-	-	-
HEMLNNMD_03534	6.06e-246	-	-	-	L	-	-	-	DNA polymerase A domain
HEMLNNMD_03535	9.53e-134	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
HEMLNNMD_03536	2.05e-207	-	-	-	-	-	-	-	-
HEMLNNMD_03537	1.57e-32	-	-	-	-	-	-	-	-
HEMLNNMD_03538	3.87e-20	-	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Crossover junction endodeoxyribonuclease RuvC
HEMLNNMD_03544	2.25e-53	-	-	-	F	-	-	-	Belongs to the NrdI family
HEMLNNMD_03545	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEMLNNMD_03547	5.14e-16	-	-	-	-	-	-	-	-
HEMLNNMD_03549	3.15e-188	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEMLNNMD_03551	3.17e-76	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	deoxyuridine 5'-triphosphate nucleotidohydrolase
HEMLNNMD_03553	4.89e-117	thyX	2.1.1.148	-	H	ko:K03465	ko00240,ko00670,ko01100,map00240,map00670,map01100	ko00000,ko00001,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HEMLNNMD_03554	2.43e-63	-	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_03556	1.54e-54	-	-	-	-	-	-	-	-
HEMLNNMD_03557	4.93e-82	-	-	-	H	-	-	-	dephospho-CoA kinase activity
HEMLNNMD_03558	1.7e-106	-	-	-	S	-	-	-	C-5 cytosine-specific DNA methylase
HEMLNNMD_03560	3.05e-39	-	-	-	K	-	-	-	Sigma-70, region 4
HEMLNNMD_03561	1.33e-44	-	-	-	-	-	-	-	-
HEMLNNMD_03562	7.23e-11	-	-	-	-	-	-	-	-
HEMLNNMD_03565	2.56e-151	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
HEMLNNMD_03567	7.61e-32	-	-	-	-	-	-	-	-
HEMLNNMD_03568	6.54e-61	-	-	-	-	-	-	-	-
HEMLNNMD_03571	2.7e-144	-	-	-	M	-	-	-	Right handed beta helix region
HEMLNNMD_03572	1.15e-67	-	-	-	S	-	-	-	Pfam:DUF867
HEMLNNMD_03573	2.71e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEMLNNMD_03574	9.08e-50	-	-	GT2	S	ko:K19425,ko:K19427	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEMLNNMD_03577	1.81e-07	-	-	-	-	-	-	-	-
HEMLNNMD_03579	1.65e-100	-	-	-	-	-	-	-	-
HEMLNNMD_03581	4.32e-42	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
HEMLNNMD_03582	1.2e-61	-	-	-	L	-	-	-	Phage terminase, small subunit
HEMLNNMD_03583	0.0	-	-	-	S	-	-	-	Terminase
HEMLNNMD_03584	2.87e-289	-	-	-	S	-	-	-	Phage portal protein
HEMLNNMD_03585	2.22e-155	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HEMLNNMD_03586	4.25e-228	-	-	-	S	-	-	-	Phage capsid family
HEMLNNMD_03588	3.82e-34	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HEMLNNMD_03589	6.42e-48	-	-	-	S	-	-	-	Phage head-tail joining protein
HEMLNNMD_03592	1.1e-91	-	-	-	N	-	-	-	phage major tail protein, phi13 family
HEMLNNMD_03593	3.26e-43	-	-	-	-	-	-	-	-
HEMLNNMD_03594	1.68e-139	-	-	-	D	-	-	-	Phage tail tape measure protein
HEMLNNMD_03595	3.96e-138	-	-	-	S	-	-	-	Phage tail protein
HEMLNNMD_03596	4.19e-237	-	-	-	L	-	-	-	Prophage endopeptidase tail
HEMLNNMD_03597	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HEMLNNMD_03598	3.93e-106	-	-	-	-	-	-	-	-
HEMLNNMD_03601	2.64e-35	-	-	-	S	-	-	-	Haemolysin XhlA
HEMLNNMD_03602	1.56e-189	-	3.5.1.28	-	MT	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEMLNNMD_03603	1.04e-45	-	-	-	S	-	-	-	Bacteriophage A118-like holin, Hol118
HEMLNNMD_03607	1.59e-20	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HEMLNNMD_03608	8.39e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HEMLNNMD_03610	1.77e-168	-	-	-	L	-	-	-	Phage integrase family
HEMLNNMD_03611	4.73e-93	-	-	-	-	-	-	-	-
HEMLNNMD_03614	1.7e-32	-	-	-	K	-	-	-	Transcriptional
HEMLNNMD_03615	7.47e-07	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_03616	6.41e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF771)
HEMLNNMD_03618	8.46e-99	-	-	-	L	-	-	-	dnaD_dom DnaD domain protein
HEMLNNMD_03619	6.54e-44	pi346	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HEMLNNMD_03621	1.85e-11	-	-	-	-	-	-	-	-
HEMLNNMD_03622	2.38e-35	-	-	-	-	-	-	-	-
HEMLNNMD_03625	1.09e-05	-	-	-	-	-	-	-	-
HEMLNNMD_03626	1.31e-20	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
HEMLNNMD_03630	3.55e-121	-	-	-	-	-	-	-	-
HEMLNNMD_03637	1.73e-08	-	-	-	-	-	-	-	-
HEMLNNMD_03638	5.84e-70	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HEMLNNMD_03639	1.23e-98	-	-	-	L	-	-	-	Phage integrase family
HEMLNNMD_03641	2.7e-11	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	PFAM cell divisionFtsK SpoIIIE
HEMLNNMD_03645	5.24e-22	-	-	-	V	-	-	-	HNH endonuclease
HEMLNNMD_03646	3.68e-59	-	-	-	-	-	-	-	-
HEMLNNMD_03647	0.0	-	-	-	L	-	-	-	Phage Terminase
HEMLNNMD_03648	1.71e-227	-	-	-	S	-	-	-	Phage portal protein
HEMLNNMD_03649	4.57e-108	-	-	-	OU	-	-	-	Clp protease
HEMLNNMD_03650	5.24e-187	-	-	-	S	-	-	-	Phage capsid family
HEMLNNMD_03651	2.56e-05	-	-	-	-	-	-	-	-
HEMLNNMD_03652	2.88e-29	-	-	-	-	-	-	-	-
HEMLNNMD_03653	3.54e-30	-	-	-	S	-	-	-	Phage head-tail joining protein
HEMLNNMD_03655	3.28e-13	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
HEMLNNMD_03656	8.37e-21	-	-	-	N	-	-	-	Maj_tail_phi13 phage major tail , phi13 family protein
HEMLNNMD_03657	4.76e-05	-	-	-	-	-	-	-	-
HEMLNNMD_03659	3.49e-169	-	-	-	D	-	-	-	phage tail tape measure protein
HEMLNNMD_03661	3e-122	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HEMLNNMD_03662	0.0	-	-	-	M	-	-	-	Pectate lyase superfamily protein
HEMLNNMD_03663	6.24e-220	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HEMLNNMD_03665	5.7e-14	-	-	-	S	-	-	-	Phage uncharacterised protein (Phage_XkdX)
HEMLNNMD_03666	2.01e-79	-	-	-	S	-	-	-	Pfam:Phage_holin_4_1
HEMLNNMD_03667	3.15e-87	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	Ami_2
HEMLNNMD_03668	5.89e-23	-	-	-	-	-	-	-	-
HEMLNNMD_03669	1.88e-51	-	-	-	-	-	-	-	-
HEMLNNMD_03671	0.0	-	-	-	C	-	-	-	Na+/H+ antiporter family
HEMLNNMD_03672	3.38e-158	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HEMLNNMD_03673	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEMLNNMD_03674	3.15e-313	ygaK	-	-	C	-	-	-	Berberine and berberine like
HEMLNNMD_03676	5.05e-86	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HEMLNNMD_03677	1.37e-182	oppA5	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 5
HEMLNNMD_03678	2.33e-185	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HEMLNNMD_03679	1.07e-162	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_03680	1.56e-169	oppD3	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_03681	4.45e-166	oppF9	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_03682	5.67e-101	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEMLNNMD_03683	3e-236	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HEMLNNMD_03684	6.85e-227	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
HEMLNNMD_03685	4.82e-175	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HEMLNNMD_03686	1.04e-221	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HEMLNNMD_03687	1.12e-183	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HEMLNNMD_03688	1.67e-270	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HEMLNNMD_03690	1.62e-53	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEMLNNMD_03691	1.56e-98	ygaO	-	-	-	-	-	-	-
HEMLNNMD_03692	1.9e-31	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_03694	5.45e-138	yhzB	-	-	S	-	-	-	B3/4 domain
HEMLNNMD_03695	4.5e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEMLNNMD_03696	2.06e-216	yhbB	-	-	S	-	-	-	Putative amidase domain
HEMLNNMD_03697	2.31e-110	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEMLNNMD_03698	9.59e-132	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HEMLNNMD_03699	1.02e-75	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HEMLNNMD_03700	6.48e-86	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HEMLNNMD_03701	1.23e-07	-	-	-	-	-	-	-	-
HEMLNNMD_03702	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HEMLNNMD_03703	2.12e-276	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HEMLNNMD_03704	1.28e-92	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HEMLNNMD_03705	2.98e-130	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HEMLNNMD_03706	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HEMLNNMD_03707	7.47e-128	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HEMLNNMD_03708	5.09e-66	yhcC	-	-	-	-	-	-	-
HEMLNNMD_03709	4.29e-64	-	-	-	-	-	-	-	-
HEMLNNMD_03710	8.78e-77	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_03711	5.37e-148	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_03712	8.81e-211	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_03713	4.59e-202	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HEMLNNMD_03714	7.28e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HEMLNNMD_03715	1.26e-166	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HEMLNNMD_03716	2.34e-172	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HEMLNNMD_03717	1.44e-290	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEMLNNMD_03718	2.84e-26	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HEMLNNMD_03719	2.24e-60	yhcM	-	-	-	-	-	-	-
HEMLNNMD_03720	2.12e-117	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HEMLNNMD_03721	5.43e-197	yhcP	-	-	-	-	-	-	-
HEMLNNMD_03722	4.1e-147	yhcQ	-	-	M	-	-	-	Spore coat protein
HEMLNNMD_03723	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HEMLNNMD_03724	9.47e-130	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HEMLNNMD_03725	2.63e-143	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEMLNNMD_03726	2.3e-48	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEMLNNMD_03727	1.88e-83	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HEMLNNMD_03728	5.88e-89	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HEMLNNMD_03729	1.33e-158	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HEMLNNMD_03730	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEMLNNMD_03731	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEMLNNMD_03732	2.75e-130	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HEMLNNMD_03733	2.6e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HEMLNNMD_03734	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEMLNNMD_03735	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HEMLNNMD_03736	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HEMLNNMD_03737	4.32e-244	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_03738	7.97e-139	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HEMLNNMD_03739	3.13e-103	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HEMLNNMD_03740	1.16e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HEMLNNMD_03741	2.33e-68	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HEMLNNMD_03742	1.88e-279	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEMLNNMD_03743	1.49e-93	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HEMLNNMD_03744	3.85e-312	ygxB	-	-	M	-	-	-	Conserved TM helix
HEMLNNMD_03745	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HEMLNNMD_03746	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HEMLNNMD_03747	2.28e-166	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HEMLNNMD_03748	5.67e-200	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_03749	8.91e-250	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HEMLNNMD_03750	1.77e-202	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_03751	1.1e-311	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HEMLNNMD_03752	1.33e-263	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEMLNNMD_03753	8.62e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HEMLNNMD_03754	2.88e-249	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HEMLNNMD_03755	4.6e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HEMLNNMD_03756	4.04e-136	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HEMLNNMD_03757	2.66e-305	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEMLNNMD_03758	2.3e-91	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HEMLNNMD_03759	3.27e-276	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HEMLNNMD_03760	5.78e-287	-	2.3.1.179	-	I	ko:K00646,ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEMLNNMD_03761	7.77e-314	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HEMLNNMD_03762	1.68e-69	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEMLNNMD_03763	4.22e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEMLNNMD_03764	1.87e-158	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HEMLNNMD_03765	1.45e-08	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HEMLNNMD_03766	3.79e-252	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HEMLNNMD_03767	4.47e-175	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEMLNNMD_03768	5.62e-191	nodB1	-	-	G	-	-	-	deacetylase
HEMLNNMD_03769	1.49e-191	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HEMLNNMD_03770	4.2e-106	pksA	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03771	1.17e-118	ymcC	-	-	S	-	-	-	Membrane
HEMLNNMD_03772	9.73e-108	-	-	-	T	-	-	-	universal stress protein
HEMLNNMD_03773	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEMLNNMD_03774	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HEMLNNMD_03775	5.82e-128	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HEMLNNMD_03777	1.91e-38	sspB	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
HEMLNNMD_03778	2.12e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HEMLNNMD_03779	9.2e-317	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HEMLNNMD_03780	2.22e-256	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HEMLNNMD_03781	1.27e-253	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HEMLNNMD_03782	2.72e-69	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HEMLNNMD_03783	2.49e-197	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HEMLNNMD_03784	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HEMLNNMD_03785	4.94e-310	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
HEMLNNMD_03786	6.38e-263	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HEMLNNMD_03787	1.53e-112	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HEMLNNMD_03789	1.32e-171	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HEMLNNMD_03790	1.47e-21	-	-	-	S	-	-	-	YhzD-like protein
HEMLNNMD_03791	4.03e-208	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_03792	7.64e-274	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HEMLNNMD_03793	1.55e-292	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HEMLNNMD_03794	0.0	yhaN	-	-	L	-	-	-	AAA domain
HEMLNNMD_03795	2.38e-224	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HEMLNNMD_03796	8.23e-43	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HEMLNNMD_03797	7.87e-183	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEMLNNMD_03798	3.56e-121	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HEMLNNMD_03799	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HEMLNNMD_03800	4.54e-144	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HEMLNNMD_03801	1.58e-53	yhaH	-	-	S	-	-	-	YtxH-like protein
HEMLNNMD_03802	2.55e-24	-	-	-	-	-	-	-	-
HEMLNNMD_03803	1.59e-97	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HEMLNNMD_03804	6.07e-252	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEMLNNMD_03805	1.17e-104	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HEMLNNMD_03806	5.22e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HEMLNNMD_03807	1.68e-276	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HEMLNNMD_03808	1.26e-154	ecsC	-	-	S	-	-	-	EcsC protein family
HEMLNNMD_03809	4.81e-274	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HEMLNNMD_03810	9.54e-303	yhfA	-	-	C	-	-	-	membrane
HEMLNNMD_03811	4.23e-115	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HEMLNNMD_03812	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HEMLNNMD_03813	1.31e-252	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HEMLNNMD_03814	3.4e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HEMLNNMD_03815	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HEMLNNMD_03816	5.15e-130	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HEMLNNMD_03817	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HEMLNNMD_03819	2.89e-226	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEMLNNMD_03821	7.07e-249	yhfE	-	-	G	-	-	-	peptidase M42
HEMLNNMD_03822	2.64e-286	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEMLNNMD_03823	9.76e-173	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HEMLNNMD_03824	1.85e-241	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HEMLNNMD_03825	3.92e-137	yhfK	-	-	GM	-	-	-	NmrA-like family
HEMLNNMD_03826	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HEMLNNMD_03827	9.31e-84	yhfM	-	-	-	-	-	-	-
HEMLNNMD_03828	4.64e-294	yhfN	-	-	O	-	-	-	Peptidase M48
HEMLNNMD_03829	1.24e-258	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEMLNNMD_03830	5.93e-162	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HEMLNNMD_03831	3.35e-131	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HEMLNNMD_03832	3.46e-244	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HEMLNNMD_03833	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HEMLNNMD_03834	2.71e-109	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HEMLNNMD_03835	2.08e-272	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HEMLNNMD_03836	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HEMLNNMD_03837	2.73e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HEMLNNMD_03838	5.49e-42	yhzC	-	-	S	-	-	-	IDEAL
HEMLNNMD_03839	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HEMLNNMD_03840	1.31e-77	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HEMLNNMD_03841	2.23e-214	-	-	-	S	-	-	-	Acetyltransferase, GNAT family
HEMLNNMD_03842	1.08e-156	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HEMLNNMD_03843	7.11e-57	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HEMLNNMD_03844	1.07e-62	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HEMLNNMD_03845	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HEMLNNMD_03846	5.59e-37	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HEMLNNMD_03847	6.59e-76	yhjD	-	-	-	-	-	-	-
HEMLNNMD_03848	8.02e-136	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HEMLNNMD_03849	3.72e-116	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HEMLNNMD_03850	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
HEMLNNMD_03851	4.02e-119	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_03852	1.37e-252	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HEMLNNMD_03853	1.34e-261	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_03854	1.02e-137	-	-	-	K	-	-	-	QacR-like protein, C-terminal region
HEMLNNMD_03855	1.72e-108	yhjR	-	-	S	-	-	-	Rubrerythrin
HEMLNNMD_03856	3.08e-152	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEMLNNMD_03857	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HEMLNNMD_03858	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HEMLNNMD_03859	2.61e-280	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEMLNNMD_03860	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HEMLNNMD_03861	3.36e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HEMLNNMD_03862	5.49e-42	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HEMLNNMD_03863	1.43e-78	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HEMLNNMD_03864	1.44e-31	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HEMLNNMD_03865	3.28e-104	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HEMLNNMD_03866	1.01e-44	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HEMLNNMD_03867	1.28e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HEMLNNMD_03868	2.45e-13	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HEMLNNMD_03869	1.3e-210	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HEMLNNMD_03870	4.48e-78	yisL	-	-	S	-	-	-	UPF0344 protein
HEMLNNMD_03871	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEMLNNMD_03872	5.25e-115	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HEMLNNMD_03873	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HEMLNNMD_03874	4.48e-152	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HEMLNNMD_03875	1.35e-276	yisQ	-	-	V	-	-	-	Mate efflux family protein
HEMLNNMD_03876	2.51e-201	yisR	-	-	K	-	-	-	Transcriptional regulator
HEMLNNMD_03877	8.2e-181	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HEMLNNMD_03878	6.95e-197	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HEMLNNMD_03879	3.8e-102	yisT	-	-	S	-	-	-	DinB family
HEMLNNMD_03880	2.91e-44	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HEMLNNMD_03881	6.72e-237	yisV	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEMLNNMD_03882	1.69e-91	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HEMLNNMD_03883	1.13e-98	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HEMLNNMD_03884	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HEMLNNMD_03885	7.44e-78	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HEMLNNMD_03886	9.46e-199	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HEMLNNMD_03887	8.05e-187	-	-	-	S	ko:K07335	-	ko00000	ABC transporter substrate-binding protein PnrA-like
HEMLNNMD_03888	1.23e-287	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
HEMLNNMD_03889	3.41e-296	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HEMLNNMD_03891	5.67e-196	yitS	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_03892	1.88e-188	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HEMLNNMD_03893	8.76e-104	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HEMLNNMD_03894	4.3e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HEMLNNMD_03895	1.49e-11	-	-	-	-	-	-	-	-
HEMLNNMD_03896	2.71e-192	-	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HEMLNNMD_03897	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HEMLNNMD_03898	3.26e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HEMLNNMD_03899	3.29e-92	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HEMLNNMD_03900	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HEMLNNMD_03901	1.33e-118	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HEMLNNMD_03902	4.41e-247	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEMLNNMD_03903	2e-259	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEMLNNMD_03904	1.78e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HEMLNNMD_03905	2.64e-266	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HEMLNNMD_03906	1.26e-245	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HEMLNNMD_03907	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HEMLNNMD_03908	8.46e-219	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEMLNNMD_03909	2.07e-38	yjzC	-	-	S	-	-	-	YjzC-like protein
HEMLNNMD_03910	3.71e-31	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HEMLNNMD_03911	4.92e-101	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HEMLNNMD_03912	5.79e-126	yjaV	-	-	-	-	-	-	-
HEMLNNMD_03913	8.66e-209	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HEMLNNMD_03914	3.74e-36	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HEMLNNMD_03915	1.46e-37	yjzB	-	-	-	-	-	-	-
HEMLNNMD_03916	1.26e-218	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEMLNNMD_03917	7.15e-296	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEMLNNMD_03918	5.83e-178	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HEMLNNMD_03919	4.64e-229	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_03920	5.46e-233	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_03921	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HEMLNNMD_03922	8.55e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_03923	7.81e-209	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_03924	5.28e-189	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HEMLNNMD_03925	8.74e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HEMLNNMD_03926	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEMLNNMD_03927	2.08e-212	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_03928	1.46e-209	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_03929	7.98e-252	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_03930	1.22e-217	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_03931	2.23e-282	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
HEMLNNMD_03932	8.52e-130	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEMLNNMD_03933	2.47e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEMLNNMD_03934	1.32e-139	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HEMLNNMD_03935	2.3e-148	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HEMLNNMD_03936	9.33e-256	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HEMLNNMD_03937	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HEMLNNMD_03938	1.28e-26	-	-	-	-	-	-	-	-
HEMLNNMD_03939	9.23e-215	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HEMLNNMD_03940	6.79e-91	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HEMLNNMD_03941	2.31e-138	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HEMLNNMD_03942	6.93e-117	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HEMLNNMD_03943	3.37e-79	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HEMLNNMD_03944	3.67e-138	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HEMLNNMD_03945	6.92e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEMLNNMD_03946	9.83e-204	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HEMLNNMD_03947	3.78e-141	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HEMLNNMD_03948	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEMLNNMD_03949	9.74e-43	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEMLNNMD_03950	2.06e-170	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEMLNNMD_03951	3.39e-131	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HEMLNNMD_03952	8.33e-255	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HEMLNNMD_03953	2.63e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	Thiamine biosynthesis
HEMLNNMD_03954	1.48e-172	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HEMLNNMD_03955	1.01e-227	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HEMLNNMD_03956	2.56e-181	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HEMLNNMD_03957	1.38e-179	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HEMLNNMD_03958	4.29e-101	yjbX	-	-	S	-	-	-	Spore coat protein
HEMLNNMD_03959	1.94e-104	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HEMLNNMD_03960	1.75e-120	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HEMLNNMD_03961	3.55e-98	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HEMLNNMD_03962	4.61e-69	cotV	-	-	S	ko:K06340	-	ko00000	Spore Coat Protein X and V domain
HEMLNNMD_03963	1.69e-72	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HEMLNNMD_03966	5.69e-05	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HEMLNNMD_03967	1.05e-50	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HEMLNNMD_03968	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HEMLNNMD_03969	1.62e-44	-	-	-	-	-	-	-	-
HEMLNNMD_03970	1.6e-167	blm	3.5.2.6	-	S	ko:K17837	ko01501,map01501	ko00000,ko00001,ko01000	Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
HEMLNNMD_03971	1.41e-154	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HEMLNNMD_03972	1.09e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HEMLNNMD_03973	1.19e-45	-	-	-	K	-	-	-	SpoVT / AbrB like domain
HEMLNNMD_03974	2.11e-92	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEMLNNMD_03975	4.03e-120	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HEMLNNMD_03976	8.87e-158	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HEMLNNMD_03977	2.18e-268	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEMLNNMD_03978	1.67e-272	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HEMLNNMD_03980	5.37e-43	-	-	-	L	-	-	-	Phage integrase family
HEMLNNMD_03981	4.33e-42	-	-	-	-	-	-	-	-
HEMLNNMD_03982	8.82e-115	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HEMLNNMD_03983	1.86e-127	-	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	2-dehydropantoate 2-reductase
HEMLNNMD_03986	2.92e-217	-	-	-	S	-	-	-	amine dehydrogenase activity
HEMLNNMD_03988	4.74e-38	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HEMLNNMD_03991	1.97e-17	-	-	-	-	-	-	-	-
HEMLNNMD_03993	2.15e-29	-	-	-	-	-	-	-	-
HEMLNNMD_03994	2.08e-30	-	-	-	-	-	-	-	-
HEMLNNMD_03997	1.3e-204	-	-	-	S	-	-	-	Putative amidase domain
HEMLNNMD_03998	1.2e-54	yjcN	-	-	-	-	-	-	-
HEMLNNMD_04001	1.37e-141	-	-	-	S	-	-	-	SEC-C Motif Domain Protein
HEMLNNMD_04002	3.97e-43	yqaS	-	-	L	-	-	-	DNA packaging
HEMLNNMD_04003	1.44e-200	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HEMLNNMD_04004	8.96e-61	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HEMLNNMD_04005	5.5e-302	yfjF	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily
HEMLNNMD_04006	3.81e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_04007	1.05e-274	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HEMLNNMD_04008	0.0	lacE	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEMLNNMD_04009	5.16e-66	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HEMLNNMD_04010	0.0	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HEMLNNMD_04011	1.39e-177	yulB	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HEMLNNMD_04012	7.94e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HEMLNNMD_04013	3.25e-44	-	-	-	-	-	-	-	-
HEMLNNMD_04014	4.16e-69	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HEMLNNMD_04015	3.93e-133	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HEMLNNMD_04016	2.62e-29	yjfB	-	-	S	-	-	-	Putative motility protein
HEMLNNMD_04017	4.94e-80	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HEMLNNMD_04018	9.54e-121	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HEMLNNMD_04019	0.0	-	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase, alpha subunit
HEMLNNMD_04020	7.9e-111	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEMLNNMD_04021	8.02e-276	yjiB	1.14.14.46	-	C	ko:K15468,ko:K16593	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HEMLNNMD_04022	1.32e-273	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HEMLNNMD_04023	1.73e-40	-	-	-	-	-	-	-	-
HEMLNNMD_04024	1.44e-180	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HEMLNNMD_04025	4.93e-150	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HEMLNNMD_04026	5.48e-160	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_04027	1.47e-220	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HEMLNNMD_04028	2.18e-112	yjlB	-	-	S	-	-	-	Cupin domain
HEMLNNMD_04029	1.7e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HEMLNNMD_04030	8.37e-278	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HEMLNNMD_04031	2.47e-98	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HEMLNNMD_04032	3.99e-232	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HEMLNNMD_04033	1.01e-206	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HEMLNNMD_04034	4.5e-113	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HEMLNNMD_04035	2.61e-166	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEMLNNMD_04036	4.35e-19	-	-	-	V	ko:K01990,ko:K20459	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_04038	3.59e-164	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HEMLNNMD_04039	2.31e-100	yjoA	-	-	S	-	-	-	DinB family
HEMLNNMD_04040	3.13e-274	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HEMLNNMD_04042	1.98e-209	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HEMLNNMD_04043	3.19e-79	yjqA	-	-	S	-	-	-	Bacterial PH domain
HEMLNNMD_04044	3.82e-128	yjqB	-	-	S	-	-	-	phage-related replication protein
HEMLNNMD_04045	2.86e-139	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HEMLNNMD_04046	1.27e-72	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HEMLNNMD_04048	8.99e-138	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HEMLNNMD_04049	2.17e-170	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HEMLNNMD_04053	2.7e-106	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HEMLNNMD_04054	1.64e-116	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HEMLNNMD_04055	3.51e-265	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HEMLNNMD_04056	2.56e-304	xkdE3	-	-	S	-	-	-	portal protein
HEMLNNMD_04057	8.47e-119	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HEMLNNMD_04058	4.58e-138	xkdG	-	-	S	-	-	-	Phage capsid family
HEMLNNMD_04059	2.95e-49	xkdG	-	-	S	-	-	-	Phage capsid family
HEMLNNMD_04060	1.26e-60	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HEMLNNMD_04062	1.98e-76	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HEMLNNMD_04063	2.59e-75	xkdJ	-	-	-	-	-	-	-
HEMLNNMD_04064	3.86e-21	-	-	-	-	-	-	-	-
HEMLNNMD_04065	3.28e-287	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HEMLNNMD_04066	8.21e-97	xkdM	-	-	S	-	-	-	Phage tail tube protein
HEMLNNMD_04067	7.28e-96	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HEMLNNMD_04068	4.33e-27	-	-	-	-	-	-	-	-
HEMLNNMD_04069	1.43e-264	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HEMLNNMD_04070	6.56e-145	xkdP	-	-	S	-	-	-	Lysin motif
HEMLNNMD_04071	2.78e-208	xkdQ	-	-	G	-	-	-	NLP P60 protein
HEMLNNMD_04072	3.05e-44	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HEMLNNMD_04073	1.65e-75	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HEMLNNMD_04074	2.53e-211	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HEMLNNMD_04075	2.77e-110	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HEMLNNMD_04076	1.48e-36	-	-	-	-	-	-	-	-
HEMLNNMD_04077	0.0	-	-	-	-	-	-	-	-
HEMLNNMD_04078	1.6e-49	xkdW	-	-	S	-	-	-	XkdW protein
HEMLNNMD_04079	2.74e-23	xkdX	-	-	-	-	-	-	-
HEMLNNMD_04080	2.51e-132	xepA	-	-	-	-	-	-	-
HEMLNNMD_04081	6.44e-50	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HEMLNNMD_04082	2.62e-49	xhlB	-	-	S	-	-	-	SPP1 phage holin
HEMLNNMD_04083	5.72e-205	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HEMLNNMD_04084	2.53e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HEMLNNMD_04085	4.26e-169	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HEMLNNMD_04086	2.36e-224	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HEMLNNMD_04087	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HEMLNNMD_04088	3.66e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HEMLNNMD_04089	1.75e-227	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HEMLNNMD_04090	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HEMLNNMD_04091	8.64e-227	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HEMLNNMD_04093	6.25e-268	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HEMLNNMD_04094	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HEMLNNMD_04095	4.88e-197	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HEMLNNMD_04096	2.68e-202	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_04097	1.12e-218	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEMLNNMD_04098	2.58e-231	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_04099	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HEMLNNMD_04100	5.18e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HEMLNNMD_04101	6.68e-243	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HEMLNNMD_04102	1.05e-199	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HEMLNNMD_04103	2.64e-200	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HEMLNNMD_04104	6.84e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HEMLNNMD_04105	7.5e-182	ykgA	-	-	E	-	-	-	Amidinotransferase
HEMLNNMD_04106	2.16e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HEMLNNMD_04107	6.07e-120	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HEMLNNMD_04108	2.03e-64	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HEMLNNMD_04109	1.73e-64	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HEMLNNMD_04110	8.86e-213	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HEMLNNMD_04111	5.43e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEMLNNMD_04112	5.73e-283	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEMLNNMD_04113	7.71e-90	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEMLNNMD_04114	6.88e-102	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HEMLNNMD_04115	3.47e-17	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEMLNNMD_04116	1.25e-63	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HEMLNNMD_04117	5.11e-71	-	-	-	D	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEMLNNMD_04119	2.92e-258	-	-	-	M	-	-	-	Glycosyl transferase family 2
HEMLNNMD_04120	1.7e-131	-	-	-	K	-	-	-	Collagen triple helix repeat
HEMLNNMD_04121	7.45e-115	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_04122	1.07e-124	-	-	-	EGP	ko:K05820	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HEMLNNMD_04123	1.82e-153	nsr	-	-	T	-	-	-	COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HEMLNNMD_04124	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEMLNNMD_04125	2.76e-221	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HEMLNNMD_04126	8.85e-181	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HEMLNNMD_04127	4.52e-162	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HEMLNNMD_04128	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HEMLNNMD_04129	7.4e-123	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HEMLNNMD_04130	2.63e-302	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HEMLNNMD_04132	7.93e-306	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HEMLNNMD_04133	3.53e-69	tnrA	-	-	K	-	-	-	transcriptional
HEMLNNMD_04134	2.24e-23	-	-	-	-	-	-	-	-
HEMLNNMD_04135	1.46e-34	ykoL	-	-	-	-	-	-	-
HEMLNNMD_04136	3.16e-104	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HEMLNNMD_04137	2.57e-127	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HEMLNNMD_04138	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HEMLNNMD_04139	4.47e-198	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HEMLNNMD_04140	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HEMLNNMD_04141	2.44e-123	ykoX	-	-	S	-	-	-	membrane-associated protein
HEMLNNMD_04142	5.75e-164	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HEMLNNMD_04143	6.02e-163	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEMLNNMD_04144	3.68e-223	ykrI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HEMLNNMD_04145	3.31e-35	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HEMLNNMD_04146	1.55e-159	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HEMLNNMD_04147	4.28e-198	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HEMLNNMD_04148	1.65e-302	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HEMLNNMD_04149	2.76e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HEMLNNMD_04150	5.59e-26	ykzE	-	-	-	-	-	-	-
HEMLNNMD_04151	1.59e-242	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HEMLNNMD_04152	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HEMLNNMD_04153	7.24e-102	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEMLNNMD_04155	2.02e-247	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HEMLNNMD_04156	6.89e-278	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HEMLNNMD_04157	5.12e-176	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HEMLNNMD_04158	1.3e-284	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HEMLNNMD_04159	5.65e-282	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HEMLNNMD_04160	2.92e-169	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HEMLNNMD_04161	2.81e-141	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HEMLNNMD_04162	5.42e-117	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HEMLNNMD_04165	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HEMLNNMD_04167	1.07e-26	-	-	-	-	-	-	-	-
HEMLNNMD_04168	1.31e-18	rok	-	-	S	-	-	-	Repressor of ComK
HEMLNNMD_04172	2.91e-73	xerD_2	-	-	L	-	-	-	Phage integrase family
HEMLNNMD_04174	9.57e-23	-	-	-	-	-	-	-	-
HEMLNNMD_04175	9.92e-33	-	-	-	-	-	-	-	-
HEMLNNMD_04178	2.12e-36	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	toxin-antitoxin pair type II binding
HEMLNNMD_04186	2.34e-39	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
HEMLNNMD_04196	2.36e-56	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HEMLNNMD_04199	2.9e-123	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
HEMLNNMD_04201	1.5e-16	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HEMLNNMD_04203	3.99e-83	-	-	-	S	-	-	-	AAA-like domain
HEMLNNMD_04206	3.39e-08	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
HEMLNNMD_04209	1.49e-197	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HEMLNNMD_04211	1.53e-59	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
HEMLNNMD_04212	1.7e-55	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
HEMLNNMD_04213	1.3e-54	-	-	-	-	ko:K18640	-	ko00000,ko04812	-
HEMLNNMD_04215	7.9e-72	-	-	-	S	-	-	-	SprT-like family
HEMLNNMD_04216	3.23e-29	-	-	-	-	-	-	-	-
HEMLNNMD_04222	7.6e-76	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HEMLNNMD_04223	1.68e-129	-	-	-	M	-	-	-	Psort location Cellwall, score
HEMLNNMD_04224	3.72e-170	-	-	-	S	-	-	-	Domain of unknown function (DUF5068)
HEMLNNMD_04225	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
HEMLNNMD_04226	4.01e-59	orfX1	-	-	L	-	-	-	Transposase
HEMLNNMD_04228	9.99e-83	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HEMLNNMD_04229	3.91e-91	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	Protein of unknown function (DUF1430)
HEMLNNMD_04233	2.59e-33	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
HEMLNNMD_04234	3.62e-50	-	-	-	-	-	-	-	-
HEMLNNMD_04235	9.34e-21	-	-	-	-	-	-	-	-
HEMLNNMD_04239	2.19e-149	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HEMLNNMD_04242	2.12e-12	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
HEMLNNMD_04245	1.06e-90	-	-	-	S	-	-	-	AAA-like domain
HEMLNNMD_04249	1.71e-127	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	Transglycosylase SLT domain
HEMLNNMD_04252	1.61e-59	-	-	-	S	-	-	-	Protein of unknown function DUF262
HEMLNNMD_04253	1.02e-30	-	-	-	-	-	-	-	-