ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PGOAFCHJ_00001 3.32e-287 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PGOAFCHJ_00002 2.17e-62 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
PGOAFCHJ_00003 4.62e-20 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L34
PGOAFCHJ_00004 2.88e-130 - 1.6.5.2 - S ko:K00355 ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418 ko00000,ko00001,ko01000 NADPH-quinone reductase (modulator of drug activity B)
PGOAFCHJ_00005 1.05e-132 - - - K - - - Transcriptional regulator
PGOAFCHJ_00006 6.76e-227 jag - - S ko:K06346 - ko00000 RNA-binding protein
PGOAFCHJ_00007 4.24e-187 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGOAFCHJ_00008 9.69e-72 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PGOAFCHJ_00009 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Argininosuccinate lyase
PGOAFCHJ_00010 3.51e-294 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PGOAFCHJ_00011 9.29e-168 fasA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulator of the LytR AlgR family
PGOAFCHJ_00012 4.16e-283 fasC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_00013 3.33e-260 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_00014 5.17e-194 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_00015 2.38e-292 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 signal transduction protein with a C-terminal ATPase domain
PGOAFCHJ_00016 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGOAFCHJ_00017 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PGOAFCHJ_00018 1.37e-155 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PGOAFCHJ_00019 1.69e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGOAFCHJ_00020 1.34e-65 - - - S - - - Protein of unknown function (DUF3397)
PGOAFCHJ_00021 2.76e-115 cah 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PGOAFCHJ_00022 1.02e-163 - - - S - - - Mitochondrial biogenesis AIM24
PGOAFCHJ_00023 1.08e-287 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGOAFCHJ_00024 4.79e-100 - 3.5.1.19 - Q ko:K08281 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PGOAFCHJ_00025 8.2e-102 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PGOAFCHJ_00026 1.58e-138 XK27_09620 - - S - - - FMN reductase (NADPH) activity
PGOAFCHJ_00027 3.61e-307 XK27_09615 - - C ko:K19784 - ko00000 reductase
PGOAFCHJ_00028 1.38e-155 nirC_1 - - P - - - Formate nitrite transporter
PGOAFCHJ_00029 2.37e-124 XK27_08585 - - S ko:K16926 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
PGOAFCHJ_00030 7.25e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PGOAFCHJ_00031 2.76e-218 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PGOAFCHJ_00032 3.26e-152 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
PGOAFCHJ_00033 1.99e-122 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGOAFCHJ_00034 6.63e-281 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PGOAFCHJ_00035 3.08e-109 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PGOAFCHJ_00036 2.91e-177 - - - S ko:K07025 - ko00000 HAD hydrolase, family IA, variant
PGOAFCHJ_00037 3.87e-201 rrmA 2.1.1.187 - Q ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 methyltransferase
PGOAFCHJ_00041 4.02e-116 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PGOAFCHJ_00042 4.45e-86 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGOAFCHJ_00043 6.94e-150 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
PGOAFCHJ_00044 4.53e-146 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGOAFCHJ_00046 2.86e-72 ytpP - - CO - - - Thioredoxin
PGOAFCHJ_00048 8.72e-259 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
PGOAFCHJ_00049 1.94e-169 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGOAFCHJ_00050 1.23e-129 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
PGOAFCHJ_00052 7.61e-139 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
PGOAFCHJ_00053 1.05e-36 lanR - - K ko:K07729 - ko00000,ko03000 sequence-specific DNA binding
PGOAFCHJ_00054 1.64e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGOAFCHJ_00055 6.55e-224 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PGOAFCHJ_00056 3.67e-17 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PGOAFCHJ_00057 3.23e-93 comGF - - U ko:K02248 - ko00000,ko00002,ko02044 Competence protein ComGF
PGOAFCHJ_00058 2.48e-21 - - - NU - - - Type II secretory pathway pseudopilin
PGOAFCHJ_00059 5.66e-91 cglD - - NU ko:K02246 - ko00000,ko00002,ko02044 Competence protein
PGOAFCHJ_00060 1.83e-61 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
PGOAFCHJ_00061 1.09e-184 cglB - - U ko:K02244 - ko00000,ko00002,ko02044 protein transport across the cell outer membrane
PGOAFCHJ_00062 1.49e-222 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PGOAFCHJ_00063 1.37e-91 - - - S - - - cog cog4699
PGOAFCHJ_00064 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGOAFCHJ_00065 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGOAFCHJ_00066 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PGOAFCHJ_00067 1.65e-304 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGOAFCHJ_00068 1.73e-246 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PGOAFCHJ_00069 8.29e-100 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PGOAFCHJ_00070 0.0 ilvB 2.2.1.6 - EH ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PGOAFCHJ_00071 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
PGOAFCHJ_00072 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
PGOAFCHJ_00073 1.87e-76 asp - - S - - - cog cog1302
PGOAFCHJ_00074 4.04e-285 norN - - V - - - Mate efflux family protein
PGOAFCHJ_00075 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
PGOAFCHJ_00076 0.000366 yebC - - M - - - Membrane
PGOAFCHJ_00078 0.0 adh 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
PGOAFCHJ_00079 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
PGOAFCHJ_00080 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
PGOAFCHJ_00081 0.0 treP 2.7.1.201 - G ko:K02817,ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00082 4.11e-161 treR - - K ko:K03486 - ko00000,ko03000 trehalose operon
PGOAFCHJ_00083 2.76e-123 ywlG - - S - - - Belongs to the UPF0340 family
PGOAFCHJ_00085 1.65e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 aldolase
PGOAFCHJ_00087 3.5e-308 - - - H - - - gamma-glutamylcysteine synthetase
PGOAFCHJ_00088 3.03e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l17
PGOAFCHJ_00089 7.63e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGOAFCHJ_00090 1.63e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGOAFCHJ_00091 4.42e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGOAFCHJ_00092 3.26e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PGOAFCHJ_00093 6.91e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGOAFCHJ_00094 4.85e-151 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PGOAFCHJ_00095 8.65e-293 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PGOAFCHJ_00096 8.47e-85 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PGOAFCHJ_00097 9.89e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein l30
PGOAFCHJ_00098 7e-104 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGOAFCHJ_00099 7.15e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGOAFCHJ_00100 5.88e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGOAFCHJ_00101 3.78e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGOAFCHJ_00102 2.03e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGOAFCHJ_00103 5.86e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGOAFCHJ_00104 5.67e-64 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGOAFCHJ_00105 2.55e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGOAFCHJ_00106 3.08e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGOAFCHJ_00107 6.2e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PGOAFCHJ_00108 4.35e-94 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGOAFCHJ_00109 9.44e-153 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGOAFCHJ_00110 1.21e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGOAFCHJ_00111 8.13e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGOAFCHJ_00112 1.45e-195 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGOAFCHJ_00113 1.21e-59 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PGOAFCHJ_00114 2.13e-135 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PGOAFCHJ_00115 3.17e-142 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGOAFCHJ_00116 4.29e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PGOAFCHJ_00117 2.95e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PGOAFCHJ_00118 0.0 XK27_09800 - - I - - - Acyltransferase
PGOAFCHJ_00119 4.22e-48 - - - S - - - MORN repeat protein
PGOAFCHJ_00120 7.37e-103 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGOAFCHJ_00121 6.38e-315 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGOAFCHJ_00122 5.52e-119 flaR - - F - - - topology modulation protein
PGOAFCHJ_00124 6.76e-251 ltrA - - S - - - Low temperature requirement protein
PGOAFCHJ_00125 7.26e-221 - - - S - - - membrane
PGOAFCHJ_00126 2.74e-117 - - - K - - - sequence-specific DNA binding
PGOAFCHJ_00127 6.84e-209 - - - L - - - Replication initiation factor
PGOAFCHJ_00128 1.37e-26 - - - S - - - Domain of unknown function (DUF3173)
PGOAFCHJ_00129 9.71e-275 - - - L - - - Belongs to the 'phage' integrase family
PGOAFCHJ_00131 5.94e-300 rarA - - L ko:K07478 - ko00000 ATPase related to the helicase subunit of the Holliday junction resolvase
PGOAFCHJ_00132 1.73e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PGOAFCHJ_00133 9.75e-59 yrzL - - S - - - Belongs to the UPF0297 family
PGOAFCHJ_00134 5.68e-91 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGOAFCHJ_00135 1.34e-62 yrzB - - S - - - Belongs to the UPF0473 family
PGOAFCHJ_00136 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_00137 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
PGOAFCHJ_00138 7.68e-20 - - - - - - - -
PGOAFCHJ_00139 1.47e-115 - - - K - - - acetyltransferase
PGOAFCHJ_00140 8.87e-150 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGOAFCHJ_00141 1.61e-156 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
PGOAFCHJ_00142 2.95e-213 XK27_01785 - - S - - - cog cog1284
PGOAFCHJ_00143 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PGOAFCHJ_00145 2.65e-305 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PGOAFCHJ_00146 1.01e-95 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00147 1.13e-169 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00148 6.09e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PGOAFCHJ_00149 8.74e-36 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PGOAFCHJ_00150 1.22e-26 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PGOAFCHJ_00151 4.15e-78 - - - L - - - An automated process has identified a potential problem with this gene model
PGOAFCHJ_00152 2.72e-117 - - - L - - - Transposase
PGOAFCHJ_00153 1.17e-59 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
PGOAFCHJ_00154 1.18e-45 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PGOAFCHJ_00155 1.07e-217 - - - T - - - Diguanylate cyclase
PGOAFCHJ_00156 1.15e-05 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
PGOAFCHJ_00157 1.55e-219 - - - M - - - COG0463, glycosyltransferases involved in cell wall biogenesis
PGOAFCHJ_00158 0.0 - 2.4.1.12 GT2 M ko:K00694 ko00500,ko01100,ko02026,map00500,map01100,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
PGOAFCHJ_00159 0.0 - - - - - - - -
PGOAFCHJ_00164 3.21e-148 XK27_06885 - - L - - - hydrolase
PGOAFCHJ_00165 9.08e-71 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator, PadR family
PGOAFCHJ_00166 8.54e-99 - - - S - - - Protein of unknown function (DUF1700)
PGOAFCHJ_00167 1.53e-146 - - - S - - - Putative adhesin
PGOAFCHJ_00168 7.55e-262 XK27_06930 - - V ko:K01421 - ko00000 domain protein
PGOAFCHJ_00169 7.72e-122 XK27_06935 - - K - - - transcriptional regulator
PGOAFCHJ_00170 2.2e-70 XK27_04840 - - M ko:K08987 - ko00000 Membrane
PGOAFCHJ_00171 5.32e-13 - - - - - - - -
PGOAFCHJ_00172 1.25e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PGOAFCHJ_00173 6.16e-63 WQ51_01655 - - S - - - Biofilm formation stimulator VEG
PGOAFCHJ_00174 1.35e-314 dnaC 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PGOAFCHJ_00175 1.77e-98 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PGOAFCHJ_00176 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PGOAFCHJ_00177 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PGOAFCHJ_00178 1.01e-129 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
PGOAFCHJ_00179 1.56e-277 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PGOAFCHJ_00180 0.0 - - - S - - - Bacterial membrane protein, YfhO
PGOAFCHJ_00181 2.93e-129 isaA - - M - - - Immunodominant staphylococcal antigen A
PGOAFCHJ_00182 7.81e-106 lytE - - M - - - LysM domain protein
PGOAFCHJ_00183 4.35e-170 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGOAFCHJ_00184 6.38e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGOAFCHJ_00185 1.5e-192 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGOAFCHJ_00186 2.68e-118 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGOAFCHJ_00187 7.05e-168 - - - S ko:K15539 - ko00000 sequence-specific DNA binding
PGOAFCHJ_00188 6.44e-301 ymfH - - S - - - Peptidase M16
PGOAFCHJ_00189 1.09e-292 albE - - S - - - Peptidase M16
PGOAFCHJ_00190 1.46e-75 yaaA - - S - - - S4 domain protein YaaA
PGOAFCHJ_00191 8.75e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGOAFCHJ_00192 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PGOAFCHJ_00193 1.93e-243 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
PGOAFCHJ_00194 3.8e-193 XK27_10395 - - S - - - membrane
PGOAFCHJ_00195 0.0 ykpA - - S - - - abc transporter atp-binding protein
PGOAFCHJ_00196 0.0 XK27_10405 - - S - - - Bacterial membrane protein YfhO
PGOAFCHJ_00200 6.36e-153 yoaK - - S - - - Protein of unknown function (DUF1275)
PGOAFCHJ_00201 8.3e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGOAFCHJ_00202 5e-275 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PGOAFCHJ_00203 1.95e-173 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PGOAFCHJ_00204 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGOAFCHJ_00205 3.38e-254 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PGOAFCHJ_00206 1.4e-40 yyzM - - S - - - Protein conserved in bacteria
PGOAFCHJ_00207 7.47e-259 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PGOAFCHJ_00208 1.8e-134 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PGOAFCHJ_00209 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGOAFCHJ_00210 1.87e-53 yabO - - J - - - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PGOAFCHJ_00211 3.9e-79 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PGOAFCHJ_00212 1.36e-05 - - - - - - - -
PGOAFCHJ_00213 2.24e-299 - 3.5.2.6 - V ko:K01467 ko01501,ko02020,map01501,map02020 ko00000,ko00001,ko00002,ko01000 Beta-lactamase enzyme family
PGOAFCHJ_00214 1.11e-299 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PGOAFCHJ_00215 3.15e-126 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
PGOAFCHJ_00216 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGOAFCHJ_00235 1.37e-156 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PGOAFCHJ_00236 2.05e-110 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
PGOAFCHJ_00237 3.23e-143 pcsB - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
PGOAFCHJ_00238 1.36e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGOAFCHJ_00239 1.56e-277 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PGOAFCHJ_00240 3.26e-180 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PGOAFCHJ_00241 8.38e-235 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PGOAFCHJ_00242 6.59e-41 acpP_1 - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGOAFCHJ_00243 5.24e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PGOAFCHJ_00244 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGOAFCHJ_00245 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGOAFCHJ_00246 6.46e-242 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PGOAFCHJ_00247 1.89e-129 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGOAFCHJ_00248 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PGOAFCHJ_00249 6.42e-200 - - - S - - - CHAP domain
PGOAFCHJ_00250 7.86e-304 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PGOAFCHJ_00251 7.32e-105 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGOAFCHJ_00252 9.42e-258 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGOAFCHJ_00253 1.44e-226 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase
PGOAFCHJ_00254 1.22e-43 - - - - - - - -
PGOAFCHJ_00255 5.33e-185 - - - J - - - Domain of unknown function (DUF4041)
PGOAFCHJ_00256 3.03e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGOAFCHJ_00258 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PGOAFCHJ_00259 1.56e-89 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PGOAFCHJ_00260 1.49e-72 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
PGOAFCHJ_00261 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGOAFCHJ_00262 1.78e-102 - - - S - - - Protein of unknown function (DUF3021)
PGOAFCHJ_00263 7.62e-92 - - - K - - - LytTr DNA-binding domain
PGOAFCHJ_00265 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PGOAFCHJ_00267 1.03e-132 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PGOAFCHJ_00268 1.5e-135 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 3-methyladenine DNA glycosylase
PGOAFCHJ_00269 1.81e-292 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PGOAFCHJ_00270 5.07e-261 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGOAFCHJ_00271 8.92e-87 spxA_2 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
PGOAFCHJ_00285 4.73e-265 - - - L - - - Belongs to the 'phage' integrase family
PGOAFCHJ_00286 1.45e-38 - - - S - - - Domain of unknown function (DUF3173)
PGOAFCHJ_00287 1.39e-88 - - - - - - - -
PGOAFCHJ_00288 2.5e-249 - - - L ko:K07467 - ko00000 Replication initiation factor
PGOAFCHJ_00289 5.19e-98 - - - - - - - -
PGOAFCHJ_00290 3.73e-99 - - - K - - - transcriptional
PGOAFCHJ_00291 2.8e-281 - - - - - - - -
PGOAFCHJ_00292 1.48e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PGOAFCHJ_00293 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGOAFCHJ_00294 6.18e-302 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
PGOAFCHJ_00295 4.88e-49 XK27_02060 - - S - - - Transglycosylase associated protein
PGOAFCHJ_00296 1.89e-95 - - - K - - - Transcriptional regulator, marr family
PGOAFCHJ_00297 2.68e-123 XK27_03570 - - S ko:K19784 - ko00000 reductase
PGOAFCHJ_00299 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 alkyl hydroperoxide reductase
PGOAFCHJ_00300 3.49e-136 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 alkyl hydroperoxide reductase
PGOAFCHJ_00301 2.48e-176 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PGOAFCHJ_00302 1.23e-233 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGOAFCHJ_00303 3.41e-107 - - - S - - - Putative small multi-drug export protein
PGOAFCHJ_00304 5.72e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PGOAFCHJ_00305 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
PGOAFCHJ_00306 4.19e-290 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PGOAFCHJ_00307 1.41e-287 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PGOAFCHJ_00308 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PGOAFCHJ_00309 3.96e-178 - - - S - - - SseB protein N-terminal domain
PGOAFCHJ_00310 6.37e-144 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine acetyltransferase
PGOAFCHJ_00312 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PGOAFCHJ_00313 1.22e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PGOAFCHJ_00315 0.0 XK27_10845 - - L - - - Domain of unknown function (DUF4368)
PGOAFCHJ_00317 1.42e-93 - - - S - - - Replication-relaxation
PGOAFCHJ_00318 1.92e-228 - - - S - - - Type IV secretion-system coupling protein DNA-binding domain
PGOAFCHJ_00319 9.7e-121 - - - KT - - - MT-A70
PGOAFCHJ_00321 1.71e-15 - - - - - - - -
PGOAFCHJ_00324 5.51e-232 sthIM 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
PGOAFCHJ_00325 0.0 sthIR 3.1.21.5 - S ko:K01156 - ko00000,ko01000,ko02048 DEAD-like helicases superfamily
PGOAFCHJ_00326 1.89e-239 - - - L - - - AAA ATPase domain
PGOAFCHJ_00327 2.6e-130 - - - L - - - AAA domain
PGOAFCHJ_00330 1.44e-171 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGOAFCHJ_00331 5.73e-120 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
PGOAFCHJ_00332 4.13e-195 yitS - - S - - - DegV family
PGOAFCHJ_00334 1.21e-40 - - - K ko:K07729 - ko00000,ko03000 Transcriptional
PGOAFCHJ_00335 7.02e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGOAFCHJ_00336 2.12e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PGOAFCHJ_00337 1.39e-278 int - - L - - - Belongs to the 'phage' integrase family
PGOAFCHJ_00338 1.67e-51 - - - S - - - Helix-turn-helix domain
PGOAFCHJ_00339 2.55e-222 isp2 - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 pathogenesis
PGOAFCHJ_00340 2.58e-41 - - - - - - - -
PGOAFCHJ_00341 0.0 - - - - - - - -
PGOAFCHJ_00342 0.0 yddE - - S - - - AAA-like domain
PGOAFCHJ_00343 5.1e-88 - - - S - - - TcpE family
PGOAFCHJ_00344 7.96e-45 - - - - - - - -
PGOAFCHJ_00345 6.68e-203 - - - S - - - Conjugative transposon protein TcpC
PGOAFCHJ_00346 3.44e-112 - - - - - - - -
PGOAFCHJ_00347 1.34e-44 - - - - - - - -
PGOAFCHJ_00348 2.98e-287 - - - K - - - Replication initiation factor
PGOAFCHJ_00349 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
PGOAFCHJ_00350 3.04e-95 - - - - - - - -
PGOAFCHJ_00351 1.59e-55 - - - - - - - -
PGOAFCHJ_00352 5.33e-61 - - - K - - - Helix-turn-helix XRE-family like proteins
PGOAFCHJ_00353 2.89e-07 - - - S - - - FRG domain
PGOAFCHJ_00354 1.35e-170 - - - E - - - IrrE N-terminal-like domain
PGOAFCHJ_00355 1.1e-135 - - - K - - - Peptidase S24-like protein
PGOAFCHJ_00356 1.56e-22 - - - L ko:K07497 - ko00000 Transposase (IS116 IS110 IS902 family)
PGOAFCHJ_00357 1.11e-10 - - - S ko:K20482 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
PGOAFCHJ_00358 1.11e-10 - - - S ko:K20482 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
PGOAFCHJ_00359 1.11e-10 - - - S ko:K20482 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
PGOAFCHJ_00361 2.66e-261 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
PGOAFCHJ_00362 1.51e-216 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ATPases associated with a variety of cellular activities
PGOAFCHJ_00363 8.68e-107 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
PGOAFCHJ_00365 1.72e-160 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 Subtilase family
PGOAFCHJ_00366 1.9e-107 spaR - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
PGOAFCHJ_00367 2.37e-125 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
PGOAFCHJ_00368 5.92e-153 - - - L - - - Transposase
PGOAFCHJ_00370 1.32e-68 - - - V ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PGOAFCHJ_00371 2.18e-106 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PGOAFCHJ_00372 9.57e-106 copY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor, CopY TcrY family
PGOAFCHJ_00373 0.0 copB 3.6.3.4 - P ko:K01533 - ko00000,ko01000 P-type ATPase
PGOAFCHJ_00375 1.1e-131 cadD - - P - - - Cadmium resistance transporter
PGOAFCHJ_00376 4.42e-73 cadX - - K ko:K21903 - ko00000,ko03000 transcriptional regulator, ArsR family
PGOAFCHJ_00377 1.17e-23 - - - - - - - -
PGOAFCHJ_00378 1.16e-63 yiiE - - S - - - protein homotetramerization
PGOAFCHJ_00380 3.02e-40 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
PGOAFCHJ_00382 6.12e-193 srtB - - S - - - Sortase family
PGOAFCHJ_00383 6.05e-295 capA - - M ko:K07282 - ko00000 Bacterial capsule synthesis protein
PGOAFCHJ_00384 3.56e-52 XK27_08630 - - T ko:K07166 - ko00000 UPF0237 protein
PGOAFCHJ_00385 5.19e-308 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
PGOAFCHJ_00386 3.28e-166 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase
PGOAFCHJ_00387 1.13e-177 yodJ 3.4.16.4, 3.4.17.14 - M ko:K01286,ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PGOAFCHJ_00388 4.75e-132 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Muramidase (Flagellum-specific)
PGOAFCHJ_00389 2.32e-237 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PGOAFCHJ_00390 6.99e-105 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGOAFCHJ_00391 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PGOAFCHJ_00392 3.12e-134 thiJ-2 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
PGOAFCHJ_00393 6.04e-252 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PGOAFCHJ_00394 1.76e-177 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PGOAFCHJ_00395 7.1e-175 thiD 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 phosphomethylpyrimidine kinase
PGOAFCHJ_00396 1.23e-105 hmpT - - S - - - cog cog4720
PGOAFCHJ_00399 1.31e-113 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
PGOAFCHJ_00400 1.67e-178 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
PGOAFCHJ_00401 1.81e-292 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PGOAFCHJ_00402 1.24e-101 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PGOAFCHJ_00403 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PGOAFCHJ_00404 5.04e-109 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
PGOAFCHJ_00405 1.5e-96 - 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
PGOAFCHJ_00406 2.88e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
PGOAFCHJ_00407 1.13e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PGOAFCHJ_00408 0.0 cpdB 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PGOAFCHJ_00409 6.05e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
PGOAFCHJ_00410 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGOAFCHJ_00411 1.36e-95 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PGOAFCHJ_00412 0.0 dex 3.2.1.11 GH66 G ko:K05988 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolase family 66
PGOAFCHJ_00413 3.18e-301 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGOAFCHJ_00414 5.97e-145 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGOAFCHJ_00415 1.83e-143 - - - K - - - Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PGOAFCHJ_00416 2.31e-244 XK27_00055 - - P - - - Major Facilitator
PGOAFCHJ_00417 3.52e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGOAFCHJ_00418 2.15e-125 - - - V - - - VanZ like family
PGOAFCHJ_00419 1.28e-303 - - - D - - - nuclear chromosome segregation
PGOAFCHJ_00422 6.47e-156 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
PGOAFCHJ_00423 2.15e-188 agrC 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
PGOAFCHJ_00424 2.66e-66 - - - - - - - -
PGOAFCHJ_00427 1.01e-165 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PGOAFCHJ_00428 3.07e-61 - - - - - - - -
PGOAFCHJ_00429 4.26e-168 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00430 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGOAFCHJ_00431 1.75e-195 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PGOAFCHJ_00433 7.31e-166 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PGOAFCHJ_00434 1.81e-241 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
PGOAFCHJ_00435 9.55e-176 sufC - - O ko:K09013 - ko00000,ko02000 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PGOAFCHJ_00436 5.68e-297 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
PGOAFCHJ_00437 1.99e-301 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGOAFCHJ_00438 2.48e-96 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
PGOAFCHJ_00439 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
PGOAFCHJ_00440 3.52e-34 - - - - - - - -
PGOAFCHJ_00441 3.85e-201 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PGOAFCHJ_00442 2.41e-233 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGOAFCHJ_00443 2.13e-93 adcR - - K - - - transcriptional
PGOAFCHJ_00444 8.41e-174 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGOAFCHJ_00445 8.96e-166 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_00446 1.15e-206 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
PGOAFCHJ_00447 0.0 ptsG 2.7.1.208 - G ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00448 1.37e-200 rgfB 3.1.3.90 - L ko:K06896 ko00500,map00500 ko00000,ko00001,ko01000 Endonuclease/Exonuclease/phosphatase family
PGOAFCHJ_00449 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PGOAFCHJ_00450 5.39e-193 Z012_04635 - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
PGOAFCHJ_00451 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter
PGOAFCHJ_00452 2.37e-161 yeeN - - K - - - transcriptional regulatory protein
PGOAFCHJ_00453 6.02e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein transport
PGOAFCHJ_00454 3.56e-182 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGOAFCHJ_00455 5.02e-185 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PGOAFCHJ_00456 1.82e-293 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PGOAFCHJ_00457 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PGOAFCHJ_00458 0.0 XK27_00665 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
PGOAFCHJ_00459 6.07e-183 cmpC - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00460 1.06e-54 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGOAFCHJ_00461 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PGOAFCHJ_00463 4.71e-57 - - - - - - - -
PGOAFCHJ_00464 5.41e-73 WQ51_06355 - - S - - - TM2 domain
PGOAFCHJ_00465 1.04e-210 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PGOAFCHJ_00466 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PGOAFCHJ_00467 2.73e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PGOAFCHJ_00468 1.05e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Belongs to the SecE SEC61-gamma family
PGOAFCHJ_00469 2.8e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PGOAFCHJ_00470 9.15e-90 - 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 - I ko:K01096,ko:K19302 ko00550,ko00564,ko01100,map00550,map00564,map01100 ko00000,ko00001,ko01000,ko01011 phosphatidate phosphatase activity
PGOAFCHJ_00471 1.56e-186 cof - - S - - - Sucrose-6F-phosphate phosphohydrolase
PGOAFCHJ_00472 1.79e-169 - - - K ko:K22103 - ko00000,ko03000 transcriptional regulator (DeoR family)
PGOAFCHJ_00473 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PGOAFCHJ_00474 3.19e-55 yjdF3 - - S - - - Protein of unknown function (DUF2992)
PGOAFCHJ_00475 1.73e-188 cylA - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00476 1.3e-179 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
PGOAFCHJ_00477 9.49e-98 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
PGOAFCHJ_00478 1.19e-40 - - - S - - - Protein of unknown function (DUF3021)
PGOAFCHJ_00479 4.11e-161 mta - - K ko:K21743 - ko00000,ko03000 Transcriptional
PGOAFCHJ_00480 5.43e-157 - - - V - - - abc transporter atp-binding protein
PGOAFCHJ_00481 1.44e-273 - - - V - - - FtsX-like permease family
PGOAFCHJ_00482 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGOAFCHJ_00483 4.15e-193 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PGOAFCHJ_00484 1.36e-95 yhaH - - S - - - Protein of unknown function (DUF805)
PGOAFCHJ_00485 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
PGOAFCHJ_00486 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PGOAFCHJ_00487 9.96e-141 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PGOAFCHJ_00488 6.21e-124 ypsA - - S - - - Belongs to the UPF0398 family
PGOAFCHJ_00489 8.01e-66 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PGOAFCHJ_00490 8.39e-281 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PGOAFCHJ_00491 0.0 mapZ - - D ko:K20073 - ko00000 Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PGOAFCHJ_00492 0.0 snf - - L - - - Superfamily II DNA RNA helicases, SNF2 family'
PGOAFCHJ_00493 4.8e-28 XK27_11680 - - - - - - -
PGOAFCHJ_00494 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PGOAFCHJ_00495 5.16e-115 - - - K - - - histone acetyltransferase HPA2 and related acetyltransferases
PGOAFCHJ_00496 0.0 mltG - - ADL ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGOAFCHJ_00497 1.17e-100 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGOAFCHJ_00498 2.63e-212 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGOAFCHJ_00499 4.71e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PGOAFCHJ_00500 2.56e-164 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGOAFCHJ_00501 2.55e-121 XK27_09705 - - S ko:K06950 - ko00000 HD superfamily hydrolase
PGOAFCHJ_00502 9.49e-143 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
PGOAFCHJ_00504 1.42e-310 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PGOAFCHJ_00505 8.96e-117 - - - K - - - transcriptional regulator
PGOAFCHJ_00506 2.31e-48 - - - S ko:K09976 - ko00000 UPF0154 protein
PGOAFCHJ_00507 2.92e-192 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PGOAFCHJ_00508 4.5e-234 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGOAFCHJ_00509 1.07e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PGOAFCHJ_00510 1.81e-113 ykuL - - S - - - CBS domain
PGOAFCHJ_00511 2.29e-172 xerD - - L - - - tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PGOAFCHJ_00512 1.17e-156 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PGOAFCHJ_00513 1.76e-118 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGOAFCHJ_00514 1.23e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PGOAFCHJ_00515 9.94e-20 yidD - - M ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
PGOAFCHJ_00516 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Cation transport protein
PGOAFCHJ_00517 7.73e-312 trkA - - P ko:K03499 - ko00000,ko02000 Potassium transporter peripheral membrane component
PGOAFCHJ_00518 5.98e-121 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PGOAFCHJ_00519 5.63e-117 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGOAFCHJ_00520 2.78e-140 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Membrane-associated phospholipid phosphatase
PGOAFCHJ_00521 4.1e-197 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
PGOAFCHJ_00522 0.0 comA - - V ko:K06147,ko:K06148,ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PGOAFCHJ_00523 1.09e-72 yhaI - - L - - - Membrane
PGOAFCHJ_00524 0.0 - - - S - - - Domain of unknown function (DUF4173)
PGOAFCHJ_00525 4.24e-186 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PGOAFCHJ_00526 7.28e-212 metQ - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
PGOAFCHJ_00527 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PGOAFCHJ_00528 2.08e-241 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGOAFCHJ_00529 1.04e-151 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_00530 5.12e-268 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PGOAFCHJ_00531 1.2e-201 ilvH - - S - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
PGOAFCHJ_00532 4.45e-122 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
PGOAFCHJ_00533 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00534 3.54e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
PGOAFCHJ_00535 1.98e-157 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PGOAFCHJ_00536 5.3e-296 ktrB - - P ko:K03498 - ko00000,ko02000 COG0168 Trk-type K transport systems, membrane components
PGOAFCHJ_00537 7.14e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Ribosomal RNA small subunit methyltransferase G
PGOAFCHJ_00538 1.89e-117 ylbN - - K ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
PGOAFCHJ_00539 1.62e-159 csrR - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGOAFCHJ_00540 0.0 covS - - T - - - Histidine kinase
PGOAFCHJ_00541 5.84e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGOAFCHJ_00542 5.84e-273 dnaB - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
PGOAFCHJ_00543 2.54e-212 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PGOAFCHJ_00544 5.05e-315 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PGOAFCHJ_00545 3.28e-140 - - - - - - - -
PGOAFCHJ_00546 1.16e-305 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGOAFCHJ_00547 7.55e-82 manO - - S - - - protein conserved in bacteria
PGOAFCHJ_00548 1.22e-216 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
PGOAFCHJ_00549 2.04e-167 manM - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
PGOAFCHJ_00550 1.39e-231 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00551 1.1e-85 manO - - S - - - Protein conserved in bacteria
PGOAFCHJ_00552 3.97e-202 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose fructose sorbose family IID component
PGOAFCHJ_00553 7.21e-170 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 pts system
PGOAFCHJ_00554 2.86e-222 manX 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00555 6.16e-173 XK27_00940 3.5.1.9 - S ko:K07130 ko00380,ko00630,ko01100,map00380,map00630,map01100 ko00000,ko00001,ko00002,ko01000 Metal-dependent hydrolase
PGOAFCHJ_00556 5.08e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PGOAFCHJ_00557 7.03e-316 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
PGOAFCHJ_00558 2.55e-100 ydiB - - M ko:K06925 - ko00000,ko03016 ATPase or kinase
PGOAFCHJ_00559 1.29e-117 XK27_05885 2.3.1.82 - M ko:K18816 - br01600,ko00000,ko01000,ko01504 phosphinothricin N-acetyltransferase activity
PGOAFCHJ_00560 5.98e-247 brpA - - K - - - Transcriptional
PGOAFCHJ_00561 1.75e-105 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PGOAFCHJ_00562 1.51e-260 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PGOAFCHJ_00563 9.2e-64 ylxR - - K ko:K07742 - ko00000 Nucleic-acid-binding protein implicated in transcription termination
PGOAFCHJ_00564 2.19e-56 ylxQ - - J - - - ribosomal protein
PGOAFCHJ_00565 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGOAFCHJ_00566 6.64e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGOAFCHJ_00567 9.66e-129 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PGOAFCHJ_00568 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGOAFCHJ_00569 0.0 ytgP - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
PGOAFCHJ_00570 0.0 pacL - - P - - - cation transport ATPase
PGOAFCHJ_00571 1.45e-257 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PGOAFCHJ_00572 1.45e-280 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PGOAFCHJ_00573 0.0 - 3.2.1.26, 3.2.1.65 GH32 G ko:K01193,ko:K01212 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PGOAFCHJ_00574 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 G ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 Belongs to the glycosyl hydrolase 68 family
PGOAFCHJ_00575 1.06e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGOAFCHJ_00576 3.75e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PGOAFCHJ_00577 7.53e-94 ylbF - - S - - - Belongs to the UPF0342 family
PGOAFCHJ_00578 6.15e-62 ylbG - - S - - - UPF0298 protein
PGOAFCHJ_00579 5.08e-270 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PGOAFCHJ_00580 1.65e-189 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGOAFCHJ_00581 1.64e-184 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGOAFCHJ_00582 9.34e-176 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PGOAFCHJ_00583 4.6e-158 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PGOAFCHJ_00584 2.56e-142 XK27_04065 - - S ko:K04767 - ko00000 CBS domain
PGOAFCHJ_00585 3.47e-214 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PGOAFCHJ_00586 2.14e-140 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
PGOAFCHJ_00587 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PGOAFCHJ_00588 9.5e-111 comFC - - K ko:K02242 - ko00000,ko00002,ko02044 competence protein
PGOAFCHJ_00589 4.11e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGOAFCHJ_00597 1.92e-212 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
PGOAFCHJ_00598 1.61e-134 - - - S - - - Domain of unknown function (DUF1803)
PGOAFCHJ_00599 1.99e-132 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PGOAFCHJ_00600 1.09e-176 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
PGOAFCHJ_00601 3.24e-315 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGOAFCHJ_00602 1.53e-244 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
PGOAFCHJ_00603 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PGOAFCHJ_00604 1.4e-147 yhfA - - S - - - HAD hydrolase, family IA, variant 3
PGOAFCHJ_00605 2.27e-179 phaB 5.3.3.14, 5.3.3.18 - I ko:K15866,ko:K18474 ko00061,ko00360,ko01120,map00061,map00360,map01120 ko00000,ko00001,ko01000,ko01004 Belongs to the enoyl-CoA hydratase isomerase family
PGOAFCHJ_00606 2.2e-95 XK27_02735 - - K - - - Transcriptional regulator, MarR family
PGOAFCHJ_00607 2.02e-219 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGOAFCHJ_00608 2.12e-40 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGOAFCHJ_00609 1.31e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 2-Nitropropane dioxygenase
PGOAFCHJ_00610 1.51e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
PGOAFCHJ_00611 5.57e-163 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PGOAFCHJ_00612 3.03e-296 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PGOAFCHJ_00613 1e-82 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGOAFCHJ_00614 1.19e-93 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGOAFCHJ_00615 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PGOAFCHJ_00616 1.91e-201 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGOAFCHJ_00617 4.63e-177 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PGOAFCHJ_00618 6.58e-116 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PGOAFCHJ_00619 6.36e-290 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PGOAFCHJ_00620 3.08e-162 fruR - - K ko:K03436 - ko00000,ko03000 transcriptional
PGOAFCHJ_00621 9.18e-212 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PGOAFCHJ_00622 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGOAFCHJ_00623 0.0 gor 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGOAFCHJ_00624 3.64e-290 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PGOAFCHJ_00625 3.68e-08 - - - - - - - -
PGOAFCHJ_00626 6.03e-270 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PGOAFCHJ_00627 1.3e-284 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGOAFCHJ_00628 0.0 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PGOAFCHJ_00629 0.0 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PGOAFCHJ_00630 1.24e-122 - 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 acetyltransferase
PGOAFCHJ_00631 1.99e-64 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PGOAFCHJ_00632 1.55e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PGOAFCHJ_00633 1.29e-166 ydaF_2 - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PGOAFCHJ_00635 2.8e-12 - - - - - - - -
PGOAFCHJ_00636 2.63e-82 WQ51_03320 - - S - - - cog cog4835
PGOAFCHJ_00637 4.62e-189 - - - S - - - EDD domain protein, DegV family
PGOAFCHJ_00638 5.21e-178 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PGOAFCHJ_00639 5.5e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PGOAFCHJ_00640 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00641 1.56e-30 - - - S - - - Short repeat of unknown function (DUF308)
PGOAFCHJ_00642 2.01e-165 - - - F - - - AdP-ribose pyrophosphatase
PGOAFCHJ_00643 2.18e-270 nadR - - H - - - adenylyltransferase
PGOAFCHJ_00644 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PGOAFCHJ_00645 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
PGOAFCHJ_00646 1.85e-90 def_1 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
PGOAFCHJ_00647 6.75e-96 - - - K - - - DNA-binding transcription factor activity
PGOAFCHJ_00648 0.0 lmrA1 - - V ko:K02021,ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00649 0.0 lmrA2 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00650 5.48e-145 - - - K - - - Acetyltransferase (GNAT) family
PGOAFCHJ_00651 5.07e-143 - 2.7.6.5 - S ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 Region found in RelA / SpoT proteins
PGOAFCHJ_00652 3.02e-153 dltr - - T - - - response regulator
PGOAFCHJ_00653 2.21e-276 sptS - - T - - - Histidine kinase
PGOAFCHJ_00654 2.78e-168 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PGOAFCHJ_00655 3.21e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PGOAFCHJ_00656 2.34e-205 yitL - - S ko:K00243 - ko00000 Protein conserved in bacteria
PGOAFCHJ_00657 2.72e-46 yozE - - S - - - Belongs to the UPF0346 family
PGOAFCHJ_00658 1.08e-205 sip - - M - - - LysM domain protein
PGOAFCHJ_00659 1.65e-242 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
PGOAFCHJ_00663 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGOAFCHJ_00664 8.15e-204 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
PGOAFCHJ_00665 3.03e-215 - - - K - - - transcriptional regulator (lysR family)
PGOAFCHJ_00666 2.87e-134 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
PGOAFCHJ_00667 0.0 - - - S - - - Glucan-binding protein C
PGOAFCHJ_00668 3.51e-224 coiA - - S ko:K06198 - ko00000 Competence protein
PGOAFCHJ_00669 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PGOAFCHJ_00670 1.43e-275 oxlT - - P ko:K08177 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGOAFCHJ_00671 5.91e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-Methyltransferase
PGOAFCHJ_00672 1.78e-234 prsA 3.1.3.16, 5.2.1.8 - O ko:K01802,ko:K03769,ko:K07533,ko:K20074 - ko00000,ko01000,ko01009,ko03110 peptidyl-prolyl cis-trans isomerase activity
PGOAFCHJ_00673 9.32e-112 XK27_03390 - - S - - - LURP-one-related
PGOAFCHJ_00674 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGOAFCHJ_00675 4.19e-210 - - - K ko:K20342,ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
PGOAFCHJ_00676 7.91e-12 - - - - - - - -
PGOAFCHJ_00678 0.0 - - - M - - - GBS Bsp-like repeat
PGOAFCHJ_00679 1.56e-277 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_00680 1.19e-176 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 response regulator
PGOAFCHJ_00682 1.14e-171 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
PGOAFCHJ_00683 2.19e-290 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PGOAFCHJ_00684 9.73e-18 - - - - - - - -
PGOAFCHJ_00685 0.0 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PGOAFCHJ_00686 1.68e-181 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PGOAFCHJ_00687 1.78e-284 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 mutations do not affect methionine salvage in vivo however
PGOAFCHJ_00688 8.29e-229 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGOAFCHJ_00689 1.06e-278 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGOAFCHJ_00690 1.04e-163 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PGOAFCHJ_00691 4.02e-261 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
PGOAFCHJ_00692 9.55e-188 icaB - - G - - - deacetylase
PGOAFCHJ_00693 1.47e-303 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PGOAFCHJ_00694 1.06e-197 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PGOAFCHJ_00695 1.22e-183 rarD - - S ko:K05786 - ko00000,ko02000 Transporter
PGOAFCHJ_00697 1.38e-17 coiA - - S ko:K06198 - ko00000 Competence protein
PGOAFCHJ_00698 1.87e-133 - - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PGOAFCHJ_00699 2.89e-09 rimL - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGOAFCHJ_00700 2.93e-123 - - - - - - - -
PGOAFCHJ_00701 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PGOAFCHJ_00702 0.0 - - - S - - - AAA ATPase domain
PGOAFCHJ_00703 5.88e-23 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGOAFCHJ_00704 3.5e-157 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PGOAFCHJ_00705 1.78e-102 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGOAFCHJ_00706 8.62e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGOAFCHJ_00707 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGOAFCHJ_00708 3.17e-202 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGOAFCHJ_00709 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGOAFCHJ_00710 1.24e-89 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PGOAFCHJ_00711 1.44e-277 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PGOAFCHJ_00712 6.46e-285 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGOAFCHJ_00713 3.13e-173 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGOAFCHJ_00714 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGOAFCHJ_00716 2.93e-143 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGOAFCHJ_00717 1.52e-204 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 dna polymerase iii
PGOAFCHJ_00718 2.01e-177 yaaT - - S - - - stage 0 sporulation protein
PGOAFCHJ_00719 2e-73 yabA - - L - - - Involved in initiation control of chromosome replication
PGOAFCHJ_00720 1.57e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGOAFCHJ_00721 9.63e-289 amt - - P ko:K03320 - ko00000,ko02000 Ammonium Transporter
PGOAFCHJ_00722 1.86e-70 glnB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
PGOAFCHJ_00723 2.18e-138 mur1 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
PGOAFCHJ_00724 4.95e-186 XK27_04800 - - S - - - Sucrose-6F-phosphate phosphohydrolase
PGOAFCHJ_00725 1.36e-105 - - - S - - - Bacterial inner membrane protein
PGOAFCHJ_00726 9.39e-163 - 3.4.17.14, 3.5.1.28 - NU ko:K01448,ko:K02395,ko:K07260 ko00550,ko01100,ko01502,ko01503,ko02020,map00550,map01100,map01502,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504,ko02035,ko03036 amidase activity
PGOAFCHJ_00727 0.0 yjbB - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
PGOAFCHJ_00728 4.53e-267 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGOAFCHJ_00729 3.57e-281 - - - S - - - membrane
PGOAFCHJ_00730 1.23e-226 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PGOAFCHJ_00731 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PGOAFCHJ_00732 1.17e-51 ynzC - - S - - - UPF0291 protein
PGOAFCHJ_00733 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 permease
PGOAFCHJ_00735 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_00736 6.12e-180 ppiA 5.2.1.8 - O ko:K01802,ko:K03767,ko:K03768 ko01503,ko04217,map01503,map04217 ko00000,ko00001,ko01000,ko03110,ko04147 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGOAFCHJ_00739 3.98e-09 - - - S - - - Protein of unknown function, DUF600
PGOAFCHJ_00740 1.56e-200 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PGOAFCHJ_00741 1.53e-71 - - - S - - - ABC-2 type transporter
PGOAFCHJ_00742 4.39e-125 - - - - - - - -
PGOAFCHJ_00744 8.2e-214 lysR - - K - - - transcriptional regulator (lysR family)
PGOAFCHJ_00745 5.69e-100 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGOAFCHJ_00746 2.52e-208 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PGOAFCHJ_00747 1.45e-114 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PGOAFCHJ_00748 1.16e-280 pyrP - - F ko:K02824 - ko00000,ko02000 uracil Permease
PGOAFCHJ_00749 5.83e-222 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PGOAFCHJ_00750 7.9e-270 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase glutamine chain
PGOAFCHJ_00751 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 carbamoyl-phosphate synthetase ammonia chain
PGOAFCHJ_00752 1.16e-163 - - - S - - - Putative SAM-dependent methyltransferase
PGOAFCHJ_00753 2.55e-248 - - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGOAFCHJ_00754 1.13e-157 salX - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGOAFCHJ_00755 7.6e-270 - - - V ko:K02004 - ko00000,ko00002,ko02000 permease protein
PGOAFCHJ_00756 8.41e-102 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGOAFCHJ_00757 5.52e-65 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PGOAFCHJ_00758 0.0 msbA_1 - - V ko:K18887 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00759 0.0 lmrA - - V ko:K06147,ko:K18888 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00760 2.28e-250 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PGOAFCHJ_00761 8.97e-159 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PGOAFCHJ_00762 1.37e-250 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
PGOAFCHJ_00763 1.61e-40 XK27_00085 - - K ko:K07729 - ko00000,ko03000 Transcriptional
PGOAFCHJ_00765 1.42e-171 - - - F - - - Phosphorylase superfamily
PGOAFCHJ_00766 1.54e-147 - - - S - - - VIT family
PGOAFCHJ_00767 1.27e-177 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PGOAFCHJ_00768 6.57e-274 hipO2 - - E ko:K01436,ko:K21613 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PGOAFCHJ_00769 3.75e-247 ald 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
PGOAFCHJ_00771 5.78e-176 - - - E - - - Alpha beta hydrolase
PGOAFCHJ_00772 4.85e-314 merA - - C - - - Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PGOAFCHJ_00773 8.55e-191 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
PGOAFCHJ_00774 2.1e-218 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
PGOAFCHJ_00775 1.96e-211 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
PGOAFCHJ_00776 1.39e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PGOAFCHJ_00777 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
PGOAFCHJ_00778 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGOAFCHJ_00779 8.64e-125 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 AdP-ribose pyrophosphatase
PGOAFCHJ_00780 1.08e-43 - - - - - - - -
PGOAFCHJ_00781 7.33e-152 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGOAFCHJ_00782 0.0 - - - M ko:K02460 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02044 domain protein
PGOAFCHJ_00783 2.97e-243 dgs 2.4.1.208 GT4 M ko:K13677 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
PGOAFCHJ_00784 5.68e-314 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
PGOAFCHJ_00786 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGOAFCHJ_00787 6.92e-206 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PGOAFCHJ_00788 2.69e-256 - - - S - - - Protein of unknown function (DUF3114)
PGOAFCHJ_00789 1.64e-39 pspC - - KT - - - PspC domain protein
PGOAFCHJ_00790 3.52e-152 hly-III - - K ko:K11068 - ko00000,ko02042 protein, Hemolysin III
PGOAFCHJ_00791 9.31e-90 - - - K - - - hmm pf08876
PGOAFCHJ_00792 2.86e-287 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
PGOAFCHJ_00793 2.1e-269 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 synthase
PGOAFCHJ_00794 2.1e-213 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGOAFCHJ_00795 9.43e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGOAFCHJ_00796 2.97e-30 - - - - - - - -
PGOAFCHJ_00797 8.89e-288 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGOAFCHJ_00798 2.75e-143 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PGOAFCHJ_00799 0.0 lysP - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PGOAFCHJ_00800 2.78e-224 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 Homocysteine
PGOAFCHJ_00801 3.14e-42 - - - S - - - Domain of unknown function (DUF1912)
PGOAFCHJ_00802 4.35e-19 - - - L - - - Helix-hairpin-helix DNA-binding motif class 1
PGOAFCHJ_00803 1.05e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PGOAFCHJ_00804 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGOAFCHJ_00805 3.54e-189 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 adenylyltransferase
PGOAFCHJ_00806 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGOAFCHJ_00807 1.68e-253 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PGOAFCHJ_00808 3.44e-22 - - - S - - - Protein of unknown function (DUF2969)
PGOAFCHJ_00811 9.51e-268 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein S1
PGOAFCHJ_00814 2.15e-139 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
PGOAFCHJ_00815 3.23e-149 - - - M - - - Pfam SNARE associated Golgi protein
PGOAFCHJ_00816 1.94e-288 murN - - V ko:K12554 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 FemAB family
PGOAFCHJ_00817 2.86e-219 - - - S - - - oxidoreductase
PGOAFCHJ_00818 2.23e-65 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
PGOAFCHJ_00819 1.3e-109 XK27_09440 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PGOAFCHJ_00820 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
PGOAFCHJ_00821 6.14e-233 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGOAFCHJ_00822 3.31e-47 ykuJ - - S - - - protein conserved in bacteria
PGOAFCHJ_00823 2.2e-151 - - - P ko:K02029 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PGOAFCHJ_00824 2.57e-168 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_00825 6.08e-102 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain protein
PGOAFCHJ_00826 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
PGOAFCHJ_00827 1.4e-11 - - - - - - - -
PGOAFCHJ_00828 3.72e-193 - - - I - - - Alpha/beta hydrolase family
PGOAFCHJ_00829 6.99e-201 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGOAFCHJ_00830 5.62e-189 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGOAFCHJ_00831 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
PGOAFCHJ_00832 2.63e-136 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGOAFCHJ_00833 2.79e-192 licT - - K ko:K03488 - ko00000,ko03000 antiterminator
PGOAFCHJ_00834 1.31e-113 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGOAFCHJ_00835 1.72e-85 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PGOAFCHJ_00836 6.73e-212 era - - M ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGOAFCHJ_00837 2.06e-193 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PGOAFCHJ_00838 4.17e-128 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGOAFCHJ_00839 9.83e-280 pmrA - - EGP ko:K08161 - ko00000,ko02000 Major Facilitator
PGOAFCHJ_00840 1.06e-44 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
PGOAFCHJ_00841 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PGOAFCHJ_00842 1.98e-105 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PGOAFCHJ_00843 0.0 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGOAFCHJ_00844 1.17e-84 yugI - - J ko:K07570 - ko00000 RNA binding protein, contains ribosomal protein S1 domain
PGOAFCHJ_00845 3.62e-247 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
PGOAFCHJ_00846 9.07e-234 ccpA - - K ko:K02529 - ko00000,ko03000 Catabolite control protein A
PGOAFCHJ_00847 8.37e-257 XK27_07735 - - S - - - YjbR
PGOAFCHJ_00848 7.15e-257 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PGOAFCHJ_00849 5.1e-102 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
PGOAFCHJ_00850 6.13e-315 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PGOAFCHJ_00851 2.95e-265 - - - S - - - Phage integrase family
PGOAFCHJ_00852 5.65e-20 - - - S - - - Pfam:Peptidase_M78
PGOAFCHJ_00855 2.61e-39 - - - S - - - sequence-specific DNA binding
PGOAFCHJ_00856 4.38e-29 - - - S - - - Protein of unknown function (DUF739)
PGOAFCHJ_00859 2.2e-33 - - - - - - - -
PGOAFCHJ_00861 1.69e-91 - - - M - - - Pilin isopeptide linkage domain protein
PGOAFCHJ_00862 2.85e-228 - - - D - - - AAA domain
PGOAFCHJ_00863 1.23e-167 - - - S - - - AAA domain
PGOAFCHJ_00864 2.01e-88 - - - - - - - -
PGOAFCHJ_00865 0.0 - - - L - - - helicase
PGOAFCHJ_00866 0.0 - - - L ko:K07505 - ko00000 Primase C terminal 2 (PriCT-2)
PGOAFCHJ_00868 3.92e-74 rusA - - L - - - crossover junction endodeoxyribonuclease RusA
PGOAFCHJ_00871 7.13e-16 - - - - - - - -
PGOAFCHJ_00874 3.9e-20 - - - S - - - Protein of unknown function (DUF1642)
PGOAFCHJ_00876 4.94e-24 - - - S - - - YopX protein
PGOAFCHJ_00879 5.48e-31 - - - L ko:K07474 - ko00000 DNA packaging
PGOAFCHJ_00880 4.59e-294 - - - S - - - Pfam:Terminase_3C
PGOAFCHJ_00881 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
PGOAFCHJ_00882 1.32e-152 - - - M - - - Phage minor capsid protein 2
PGOAFCHJ_00883 1.11e-120 - - - S - - - Phage minor structural protein GP20
PGOAFCHJ_00884 4.9e-180 - - - S - - - peptidase activity
PGOAFCHJ_00886 1.55e-72 - - - - - - - -
PGOAFCHJ_00888 3.27e-33 - - - S - - - Minor capsid protein
PGOAFCHJ_00889 6.13e-70 - - - S - - - Minor capsid protein from bacteriophage
PGOAFCHJ_00890 1.21e-96 - - - - - - - -
PGOAFCHJ_00891 8.27e-31 - - - - - - - -
PGOAFCHJ_00892 2.3e-109 - - - S - - - Bacteriophage Gp15 protein
PGOAFCHJ_00893 0.0 - - - S - - - transmembrane transport
PGOAFCHJ_00894 2.84e-136 - - - - - - - -
PGOAFCHJ_00895 2.71e-213 - - - S - - - peptidoglycan catabolic process
PGOAFCHJ_00897 7.85e-75 - - - S - - - Pfam:Phage_holin_4_1
PGOAFCHJ_00898 4.23e-32 hol - - S - - - COG5546 Small integral membrane protein
PGOAFCHJ_00899 0.000332 - - - - - - - -
PGOAFCHJ_00902 7.6e-97 - - - S - - - peptidoglycan catabolic process
PGOAFCHJ_00903 1.1e-34 WQ51_00785 - - - - - - -
PGOAFCHJ_00904 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PGOAFCHJ_00905 6.89e-279 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PGOAFCHJ_00906 6.81e-150 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PGOAFCHJ_00907 1.69e-198 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PGOAFCHJ_00908 4.84e-256 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PGOAFCHJ_00909 8.7e-278 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGOAFCHJ_00910 6.17e-261 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PGOAFCHJ_00911 2.99e-71 XK26_04240 - - S - - - Belongs to the UPF0342 family
PGOAFCHJ_00912 9.55e-216 hicD2 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
PGOAFCHJ_00913 4.86e-297 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PGOAFCHJ_00914 7.63e-112 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGOAFCHJ_00915 2.42e-197 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PGOAFCHJ_00916 0.0 msrR - - K - - - Transcriptional regulator
PGOAFCHJ_00917 2.15e-194 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 C4-dicarboxylate transporter malic acid transport
PGOAFCHJ_00918 5.22e-255 - - - I - - - acyl-CoA dehydrogenase
PGOAFCHJ_00919 1.28e-126 mip - - S - - - hydroperoxide reductase activity
PGOAFCHJ_00920 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGOAFCHJ_00921 7.84e-71 - - - K - - - TfoX N-terminal domain
PGOAFCHJ_00922 1.1e-90 - - - E - - - cog cog0346
PGOAFCHJ_00923 5.7e-199 - - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator, effector binding domain protein
PGOAFCHJ_00924 1.75e-117 - - - K - - - Acetyltransferase (GNAT) domain
PGOAFCHJ_00925 3.49e-125 - - - - - - - -
PGOAFCHJ_00926 5.57e-174 - - - S - - - CAAX protease self-immunity
PGOAFCHJ_00927 1.46e-204 - - - K - - - DNA-binding helix-turn-helix protein
PGOAFCHJ_00928 4.25e-174 - - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PGOAFCHJ_00929 8.39e-261 yycB - - P ko:K03449 - ko00000,ko02000 transporter
PGOAFCHJ_00930 2.13e-194 ChZ00x2 - - S - - - EDD domain protein, DegV family
PGOAFCHJ_00931 9.47e-124 - - - K - - - Bacterial regulatory proteins, tetR family
PGOAFCHJ_00932 1.05e-137 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
PGOAFCHJ_00934 1.6e-184 - - - S - - - Domain of unknown function (DUF4300)
PGOAFCHJ_00935 5.25e-157 - - - V - - - CAAX protease self-immunity
PGOAFCHJ_00936 5.83e-217 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGOAFCHJ_00937 1.67e-172 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PGOAFCHJ_00938 1.82e-231 fatB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PGOAFCHJ_00939 1.42e-154 - - - S - - - Putative esterase
PGOAFCHJ_00940 5.92e-203 yegS - - I - - - Diacylglycerol kinase
PGOAFCHJ_00941 4.08e-218 - - - S - - - Domain of unknown function (DUF389)
PGOAFCHJ_00943 2.58e-41 - - - S - - - Transglycosylase associated protein
PGOAFCHJ_00944 2.41e-126 - - - - - - - -
PGOAFCHJ_00945 3.07e-32 - - - S - - - Small integral membrane protein
PGOAFCHJ_00946 3.1e-93 - - - S - - - Asp23 family, cell envelope-related function
PGOAFCHJ_00947 7.79e-25 - - - K - - - CsbD-like
PGOAFCHJ_00948 1.53e-215 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
PGOAFCHJ_00949 5.03e-211 acoA - - C ko:K21416 - ko00000,ko01000 Acetoin dehydrogenase E1 component subunit alpha
PGOAFCHJ_00950 5.3e-222 acoB - - C ko:K21417 - ko00000,ko01000 dehydrogenase E1 component
PGOAFCHJ_00951 3.08e-179 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGOAFCHJ_00952 9.38e-104 - - - Q - - - Methyltransferase domain
PGOAFCHJ_00953 1.92e-95 - - - K - - - TetR family transcriptional regulator
PGOAFCHJ_00954 1.27e-61 - - - - - - - -
PGOAFCHJ_00955 1.42e-161 - - - V - - - CAAX protease self-immunity
PGOAFCHJ_00957 8.9e-30 - - - M - - - Bacterial lipoprotein
PGOAFCHJ_00958 1.61e-79 - - - S - - - Protein of unknown function (DUF1722)
PGOAFCHJ_00959 5.83e-84 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
PGOAFCHJ_00961 1.03e-65 - - - - - - - -
PGOAFCHJ_00962 1.36e-120 - - - S - - - CAAX protease self-immunity
PGOAFCHJ_00963 2.23e-149 - - - E - - - GDSL-like Lipase/Acylhydrolase
PGOAFCHJ_00964 4.28e-129 - - - - - - - -
PGOAFCHJ_00965 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 Sulfate permease and related transporters (MFS superfamily)
PGOAFCHJ_00966 3.27e-189 XK27_03010 - - S ko:K08986 - ko00000 TIGR03943 family
PGOAFCHJ_00967 1.88e-198 XK27_03015 - - S ko:K07089 - ko00000 permease
PGOAFCHJ_00969 0.0 tex - - K ko:K06959 - ko00000 Transcriptional accessory protein
PGOAFCHJ_00970 1.02e-55 WQ51_05770 - - KT - - - PspC domain
PGOAFCHJ_00971 1.46e-211 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PGOAFCHJ_00972 8.04e-186 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGOAFCHJ_00973 9.98e-28 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PGOAFCHJ_00974 1.86e-88 ytxH - - S - - - General stress protein
PGOAFCHJ_00976 4.13e-227 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PGOAFCHJ_00977 0.0 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PGOAFCHJ_00978 1.73e-109 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 biotin synthase
PGOAFCHJ_00980 2.97e-45 XK27_12190 - - S - - - protein conserved in bacteria
PGOAFCHJ_00981 1.21e-290 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PGOAFCHJ_00982 2.54e-19 - - - - - - - -
PGOAFCHJ_00983 2.4e-265 dcm 2.1.1.37 - H ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
PGOAFCHJ_00984 2.44e-192 - - - L - - - DNA mismatch repair enzyme MutH
PGOAFCHJ_00986 1.56e-277 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_00987 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PGOAFCHJ_00988 1.59e-206 - - - M - - - LysM domain
PGOAFCHJ_00989 1.22e-36 - - - - - - - -
PGOAFCHJ_00990 3.26e-224 - - - S ko:K07025 - ko00000 hydrolase
PGOAFCHJ_00992 2.41e-148 pgm - - G - - - Phosphoglycerate mutase
PGOAFCHJ_00993 8.68e-106 - - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGOAFCHJ_00994 9.55e-192 - 3.5.1.28 - M ko:K01447,ko:K07273 - ko00000,ko01000 Glycosyl hydrolase, family 25
PGOAFCHJ_00995 3.75e-34 - - - P - - - Hemerythrin HHE cation binding domain protein
PGOAFCHJ_00996 8.1e-199 hmpP2 - - G - - - hydrolase
PGOAFCHJ_00997 2.07e-147 - - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGOAFCHJ_00998 2.45e-269 - - - S - - - Protein of unknown function (DUF2974)
PGOAFCHJ_00999 1.22e-171 sdh - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PGOAFCHJ_01000 4.74e-61 - - - S - - - Phage derived protein Gp49-like (DUF891)
PGOAFCHJ_01001 4.88e-60 - - - K - - - Helix-turn-helix domain
PGOAFCHJ_01002 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
PGOAFCHJ_01003 6.89e-93 - - - S - - - Protein of unknown function (DUF1524)
PGOAFCHJ_01004 5.19e-150 - - - V - - - Type I restriction modification DNA specificity domain
PGOAFCHJ_01005 8.56e-306 - - - EP - - - AAA domain, putative AbiEii toxin, Type IV TA system
PGOAFCHJ_01006 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
PGOAFCHJ_01007 1.01e-178 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
PGOAFCHJ_01008 1.1e-34 - - - S - - - double-stranded DNA endodeoxyribonuclease activity
PGOAFCHJ_01009 0.0 - - - M - - - Right handed beta helix region
PGOAFCHJ_01010 8.87e-120 lemA - - S ko:K03744 - ko00000 LemA family
PGOAFCHJ_01011 2.43e-189 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PGOAFCHJ_01012 2.82e-153 sirR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
PGOAFCHJ_01013 3.77e-218 psaA - - P ko:K11704,ko:K19971,ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PGOAFCHJ_01014 4.11e-171 mtsC - - P ko:K11705,ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type Mn2 Zn2 transport systems, permease components
PGOAFCHJ_01015 3.23e-161 sitB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K10830,ko:K11706,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGOAFCHJ_01016 9.64e-94 - - - S ko:K16927 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
PGOAFCHJ_01017 1.54e-82 - - - S - - - Domain of unknown function (DUF4430)
PGOAFCHJ_01018 0.0 ppc 4.1.1.31 - H ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PGOAFCHJ_01019 3.69e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PGOAFCHJ_01020 1.59e-143 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
PGOAFCHJ_01021 1.3e-211 - - - V - - - D-alanyl-D-alanine carboxypeptidase
PGOAFCHJ_01022 2.33e-133 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PGOAFCHJ_01023 1.06e-116 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PGOAFCHJ_01024 8.12e-103 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PGOAFCHJ_01025 2.18e-36 yqgQ - - S - - - protein conserved in bacteria
PGOAFCHJ_01026 3.26e-226 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PGOAFCHJ_01027 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PGOAFCHJ_01028 5.19e-12 - - - S - - - Protein of unknown function (DUF3165)
PGOAFCHJ_01029 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGOAFCHJ_01030 1.5e-255 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGOAFCHJ_01031 1.72e-184 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PGOAFCHJ_01032 4.95e-292 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PGOAFCHJ_01033 3.44e-299 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGOAFCHJ_01034 1.62e-158 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PGOAFCHJ_01035 2.34e-128 sepF - - D ko:K09772 - ko00000,ko03036 cell septum assembly
PGOAFCHJ_01036 1.13e-40 yggT - - D ko:K02221 - ko00000,ko02044 integral membrane protein
PGOAFCHJ_01037 2.12e-183 ylmH - - S - - - conserved protein, contains S4-like domain
PGOAFCHJ_01038 2.89e-193 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
PGOAFCHJ_01039 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGOAFCHJ_01040 1.56e-277 - - - L - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_01041 5.27e-235 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGOAFCHJ_01042 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGOAFCHJ_01043 3.36e-46 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
PGOAFCHJ_01044 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PGOAFCHJ_01045 1e-269 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PGOAFCHJ_01046 4.87e-281 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Isocitrate dehydrogenase
PGOAFCHJ_01047 2.72e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein Hpr
PGOAFCHJ_01048 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGOAFCHJ_01049 0.0 gapN 1.2.1.9 - C ko:K00131 ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PGOAFCHJ_01050 5.11e-204 XK27_05670 - - S ko:K07017 - ko00000 Putative esterase
PGOAFCHJ_01051 5.31e-196 XK27_05675 - - S - - - Esterase
PGOAFCHJ_01052 1.16e-286 XK27_05680 - - M - - - carbamoylphosphate synthase large subunit
PGOAFCHJ_01053 1.58e-227 yfmL - - L - - - DEAD DEAH box helicase
PGOAFCHJ_01054 5.27e-147 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PGOAFCHJ_01055 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 abc transporter atp-binding protein
PGOAFCHJ_01056 7.55e-53 - - - S - - - yiaA/B two helix domain
PGOAFCHJ_01057 2.59e-170 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha beta hydrolase
PGOAFCHJ_01058 0.0 mprF 2.3.2.3 - J ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGOAFCHJ_01059 1.2e-191 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
PGOAFCHJ_01060 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain protein
PGOAFCHJ_01061 9.63e-191 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGOAFCHJ_01062 3.03e-210 ybbR - - S - - - Protein conserved in bacteria
PGOAFCHJ_01063 6.47e-316 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGOAFCHJ_01064 5.03e-84 mesH - - S - - - GtrA-like protein
PGOAFCHJ_01065 2.9e-157 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PGOAFCHJ_01066 4.3e-185 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGOAFCHJ_01067 2.66e-186 zupT - - P ko:K07238 - ko00000,ko02000 Mediates zinc uptake. May also transport other divalent cations
PGOAFCHJ_01068 3.8e-252 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 oxidoreductase
PGOAFCHJ_01069 0.0 - - - S - - - phospholipase Carboxylesterase
PGOAFCHJ_01070 6.44e-205 rfbA 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PGOAFCHJ_01071 1.36e-142 rmlC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PGOAFCHJ_01072 4.51e-262 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PGOAFCHJ_01075 6.32e-275 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PGOAFCHJ_01076 1.02e-180 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
PGOAFCHJ_01077 7.1e-177 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PGOAFCHJ_01078 1.84e-153 - - - S - - - tigr01906
PGOAFCHJ_01079 3.69e-178 hisJ 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
PGOAFCHJ_01080 4.59e-198 XK27_08080 - - G - - - Exopolysaccharide biosynthesis protein
PGOAFCHJ_01081 1.75e-78 XK27_08085 - - - - - - -
PGOAFCHJ_01082 8.86e-245 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGOAFCHJ_01083 7.68e-227 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PGOAFCHJ_01084 2.93e-151 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PGOAFCHJ_01085 7.21e-299 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGOAFCHJ_01086 2.36e-137 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PGOAFCHJ_01087 1.65e-141 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGOAFCHJ_01088 3.39e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGOAFCHJ_01089 5.63e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGOAFCHJ_01090 1.66e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PGOAFCHJ_01091 1.27e-66 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 - E ko:K01523,ko:K01814,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
PGOAFCHJ_01093 1.88e-132 XK27_05505 - - S - - - Psort location CytoplasmicMembrane, score
PGOAFCHJ_01094 3.98e-184 - - - P - - - molecular chaperone
PGOAFCHJ_01095 6.32e-167 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
PGOAFCHJ_01096 4.11e-229 - - - M - - - glycosyl transferase family 2
PGOAFCHJ_01097 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
PGOAFCHJ_01098 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
PGOAFCHJ_01099 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
PGOAFCHJ_01100 4.6e-308 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PGOAFCHJ_01101 1.24e-312 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGOAFCHJ_01102 2.14e-147 XK27_05445 - - G - - - UDPglucose--hexose-1-phosphate uridylyltransferase
PGOAFCHJ_01103 1.81e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PGOAFCHJ_01104 5.59e-173 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGOAFCHJ_01105 1.16e-27 - - - Q - - - Methyltransferase domain
PGOAFCHJ_01106 2.01e-84 GnaT 2.5.1.16 - K ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferase
PGOAFCHJ_01107 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease recj
PGOAFCHJ_01108 7.52e-121 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGOAFCHJ_01109 4.66e-231 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PGOAFCHJ_01110 3.15e-163 dnaD - - - ko:K02086 - ko00000 -
PGOAFCHJ_01111 5.28e-153 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PGOAFCHJ_01113 4.4e-297 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGOAFCHJ_01114 2.44e-40 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGOAFCHJ_01115 7.15e-198 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PGOAFCHJ_01116 9e-189 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
PGOAFCHJ_01117 4.21e-95 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PGOAFCHJ_01118 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PGOAFCHJ_01119 4.76e-186 WQ51_01275 - - S - - - DegV family
PGOAFCHJ_01120 3.72e-205 XK27_03630 - - E - - - COG2755 Lysophospholipase L1 and related esterases
PGOAFCHJ_01121 9.58e-126 ypmS - - S - - - Protein conserved in bacteria
PGOAFCHJ_01122 3.1e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PGOAFCHJ_01124 1.68e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
PGOAFCHJ_01125 2.15e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PGOAFCHJ_01126 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGOAFCHJ_01127 2.73e-241 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PGOAFCHJ_01128 2e-49 ysdA - - L - - - Membrane
PGOAFCHJ_01129 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGOAFCHJ_01130 5.58e-146 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGOAFCHJ_01131 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PGOAFCHJ_01132 4.51e-237 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PGOAFCHJ_01133 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PGOAFCHJ_01134 0.0 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_01135 0.0 crpB - - Q - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_01137 3.96e-228 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
PGOAFCHJ_01138 1.37e-190 XK27_08840 - - S ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGOAFCHJ_01139 9.34e-175 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01140 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGOAFCHJ_01141 4.17e-191 estA - CE1 S ko:K03930 - ko00000,ko01000 Esterase
PGOAFCHJ_01142 3.8e-163 XK27_08875 - - O - - - Zinc-dependent metalloprotease
PGOAFCHJ_01143 6.66e-24 XK27_08880 - - - - - - -
PGOAFCHJ_01144 2.45e-98 ykuP - - C ko:K03839 - ko00000 Flavodoxin
PGOAFCHJ_01145 0.0 eriC - - P ko:K03281 - ko00000 Chloride transporter, ClC family
PGOAFCHJ_01146 3e-54 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 - E ko:K00661,ko:K04092,ko:K04093,ko:K04516,ko:K14170,ko:K14187 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
PGOAFCHJ_01147 6.74e-269 eriC - - P ko:K03281 - ko00000 Chloride transporter ClC family
PGOAFCHJ_01148 2.33e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PGOAFCHJ_01151 9.42e-28 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
PGOAFCHJ_01152 2.16e-210 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGOAFCHJ_01153 2.16e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PGOAFCHJ_01154 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGOAFCHJ_01155 2.78e-222 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PGOAFCHJ_01156 1.8e-270 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGOAFCHJ_01157 0.0 - 5.1.3.2 - GM ko:K01784,ko:K21009 ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score
PGOAFCHJ_01158 9.7e-185 - - - - - - - -
PGOAFCHJ_01159 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2194)
PGOAFCHJ_01160 0.0 - 2.4.1.52 GT4 M ko:K00712,ko:K21011 ko02025,map02025 ko00000,ko00001,ko01000,ko01003 Domain of unknown function (DUF3492)
PGOAFCHJ_01161 5.17e-241 - - - M ko:K21012 ko02025,map02025 ko00000,ko00001 Putative exopolysaccharide Exporter (EPS-E)
PGOAFCHJ_01162 2.08e-280 - - - M ko:K06330 - ko00000 CotH kinase protein
PGOAFCHJ_01163 9.2e-123 - - - P - - - VTC domain
PGOAFCHJ_01164 6.52e-108 - - - S - - - membrane
PGOAFCHJ_01165 2.19e-167 - - - G - - - Domain of unknown function (DUF4832)
PGOAFCHJ_01166 7.06e-249 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PGOAFCHJ_01167 1.56e-13 - - - S - - - Protein of unknown function (DUF1146)
PGOAFCHJ_01168 1.45e-296 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGOAFCHJ_01169 1.43e-35 - - - S - - - DNA-directed RNA polymerase subunit beta
PGOAFCHJ_01170 4.47e-198 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
PGOAFCHJ_01171 1.75e-143 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PGOAFCHJ_01172 8.31e-159 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01173 1.12e-183 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGOAFCHJ_01174 4.28e-177 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01175 1.75e-143 - - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PGOAFCHJ_01176 8.31e-159 XK27_07620 - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01177 1.56e-190 peb1A - - ET ko:K02030,ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGOAFCHJ_01178 3.14e-179 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01179 1.44e-165 yycF - - KT ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGOAFCHJ_01180 2.59e-311 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGOAFCHJ_01181 5.93e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Metal-dependent hydrolases of the beta-lactamase superfamily I
PGOAFCHJ_01182 6.33e-74 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
PGOAFCHJ_01183 1.86e-287 femX 2.3.2.10, 2.3.2.16 - V ko:K05363,ko:K11693 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01011 protein involved in methicillin resistance
PGOAFCHJ_01184 1.89e-187 XK27_00835 - - S - - - hydrolases of the HAD superfamily
PGOAFCHJ_01185 1.42e-187 XK27_00115 - - K - - - Acetyltransferase GNAT family
PGOAFCHJ_01186 2.05e-90 ywiB - - S - - - Domain of unknown function (DUF1934)
PGOAFCHJ_01187 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 cation transport ATPase
PGOAFCHJ_01188 6.31e-171 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
PGOAFCHJ_01189 3.55e-203 - - - S - - - Calcineurin-like phosphoesterase
PGOAFCHJ_01190 4.07e-268 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PGOAFCHJ_01191 1.08e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGOAFCHJ_01192 8.67e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
PGOAFCHJ_01193 8.45e-211 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PGOAFCHJ_01194 3.39e-118 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGOAFCHJ_01195 1.22e-231 XK27_05220 - - S - - - permease
PGOAFCHJ_01196 1.7e-281 XK27_05225 - - G - - - COG0457 FOG TPR repeat
PGOAFCHJ_01197 1.8e-123 sipC 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PGOAFCHJ_01198 0.0 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
PGOAFCHJ_01199 4.96e-289 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PGOAFCHJ_01200 2.86e-113 ebsA - - S - - - Family of unknown function (DUF5322)
PGOAFCHJ_01201 1.03e-45 XK27_09115 - - M - - - LysM domain
PGOAFCHJ_01202 3.96e-154 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PGOAFCHJ_01203 1.1e-115 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGOAFCHJ_01204 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PGOAFCHJ_01205 1.05e-72 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGOAFCHJ_01206 1.4e-96 XK27_03610 - - K - - - Gnat family
PGOAFCHJ_01207 3.42e-113 yybC - - - - - - -
PGOAFCHJ_01208 1.38e-37 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
PGOAFCHJ_01209 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Dipeptidase
PGOAFCHJ_01210 2.46e-139 ung2 - - L - - - Uracil-DNA glycosylase
PGOAFCHJ_01211 0.0 - - - V - - - Glucan-binding protein C
PGOAFCHJ_01212 0.0 - - - V ko:K13732 ko05100,map05100 ko00000,ko00001 Glucan-binding protein C
PGOAFCHJ_01213 5.87e-156 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PGOAFCHJ_01214 9.63e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
PGOAFCHJ_01215 2.69e-123 - - - S - - - Protein of unknown function (DUF1697)
PGOAFCHJ_01216 3.01e-184 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PGOAFCHJ_01217 1.2e-66 - - - S ko:K03744 - ko00000 LemA family
PGOAFCHJ_01218 1.98e-202 clcA2 - - P - - - chloride
PGOAFCHJ_01219 1.23e-167 gat 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 glutamine amidotransferase
PGOAFCHJ_01220 3.97e-168 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine nucleoside phosphorylase
PGOAFCHJ_01221 1.51e-314 cps4A - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
PGOAFCHJ_01222 2.9e-169 cpsB 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 Capsular polysaccharide biosynthesis protein
PGOAFCHJ_01223 2.52e-143 capA - - M - - - biosynthesis protein
PGOAFCHJ_01224 3.69e-153 cpsD - - D - - - COG0489 ATPases involved in chromosome partitioning
PGOAFCHJ_01225 0.0 cpsE - - M - - - Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PGOAFCHJ_01226 2e-284 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 group 1 family protein
PGOAFCHJ_01227 1.72e-267 - - - M - - - Glycosyltransferase, group 1 family protein
PGOAFCHJ_01228 5.71e-154 - - - M - - - Domain of unknown function (DUF1919)
PGOAFCHJ_01229 6.06e-207 - - - M - - - Glycosyltransferase, group 2 family protein
PGOAFCHJ_01230 1.07e-195 - - - M - - - Glycosyltransferase like family 2
PGOAFCHJ_01231 5.82e-221 - - - - - - - -
PGOAFCHJ_01232 1.15e-315 wzx - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
PGOAFCHJ_01233 2.16e-204 - - - S - - - Acyltransferase family
PGOAFCHJ_01234 8.61e-276 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
PGOAFCHJ_01235 7.49e-236 wefC - - M - - - Stealth protein CR2, conserved region 2
PGOAFCHJ_01236 7.46e-237 - - - M - - - transferase activity, transferring glycosyl groups
PGOAFCHJ_01238 1.57e-192 supH - - S - - - Sucrose-6F-phosphate phosphohydrolase
PGOAFCHJ_01239 1.16e-140 XK27_06100 - - G - - - Belongs to the phosphoglycerate mutase family
PGOAFCHJ_01240 1.58e-139 - - - G - - - Belongs to the phosphoglycerate mutase family
PGOAFCHJ_01241 3.41e-142 - - - G - - - Belongs to the phosphoglycerate mutase family
PGOAFCHJ_01242 2.66e-251 XK27_12525 - - S - - - hmm pf01594
PGOAFCHJ_01243 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGOAFCHJ_01244 3.34e-52 - - - S - - - granule-associated protein
PGOAFCHJ_01245 0.0 ubiB - - S ko:K03688 - ko00000 unusual protein kinase
PGOAFCHJ_01246 8.9e-130 - - - E - - - Lysophospholipase L1 and related esterases
PGOAFCHJ_01247 8.75e-200 - - - S - - - Phospholipase, patatin family
PGOAFCHJ_01248 1.85e-228 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
PGOAFCHJ_01249 2.78e-316 dacA1 3.4.16.4 - M ko:K01286 - ko00000,ko01000 Belongs to the peptidase S11 family
PGOAFCHJ_01250 7.73e-277 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGOAFCHJ_01251 5.46e-152 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGOAFCHJ_01252 3.43e-299 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGOAFCHJ_01253 0.0 - - - S - - - the current gene model (or a revised gene model) may contain a frame shift
PGOAFCHJ_01254 8.63e-292 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_01255 2.26e-258 hpk9 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_01256 1.02e-234 acoA 1.2.4.1 - C ko:K00161,ko:K21416 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
PGOAFCHJ_01257 3.82e-230 acoB 1.2.4.1 - C ko:K00162,ko:K21417 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGOAFCHJ_01258 3.97e-275 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGOAFCHJ_01259 0.0 lpdA 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
PGOAFCHJ_01260 0.0 - 3.5.1.28 - S ko:K01448,ko:K02395,ko:K21471 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko02035,ko03036 dextransucrase activity
PGOAFCHJ_01261 2.73e-254 amiA 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-Acetylmuramoyl-L-alanine amidase
PGOAFCHJ_01262 7.67e-134 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
PGOAFCHJ_01263 0.0 pulA2 3.2.1.1, 3.2.1.41 CBM48,GH13 G ko:K01176,ko:K01200 ko00500,ko01100,ko01110,ko04973,map00500,map01100,map01110,map04973 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
PGOAFCHJ_01264 3.8e-193 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
PGOAFCHJ_01265 2.89e-294 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 peroxidase
PGOAFCHJ_01266 0.0 ywbL - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
PGOAFCHJ_01267 5.35e-160 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGOAFCHJ_01268 6.81e-34 tatA - - U ko:K03116,ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
PGOAFCHJ_01269 1.94e-269 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGOAFCHJ_01270 2.6e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01271 9.2e-317 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01272 6.81e-291 malX - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGOAFCHJ_01273 5.29e-221 malR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PGOAFCHJ_01274 0.0 malQ 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 4-alpha-glucanotransferase
PGOAFCHJ_01275 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PGOAFCHJ_01277 6.93e-236 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PGOAFCHJ_01278 1.78e-246 xerS - - D ko:K04763 - ko00000,ko03036 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PGOAFCHJ_01279 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
PGOAFCHJ_01280 1.56e-147 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
PGOAFCHJ_01281 2.49e-179 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGOAFCHJ_01282 7.48e-193 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGOAFCHJ_01283 3.12e-200 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate transport system permease
PGOAFCHJ_01284 1.33e-200 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PGOAFCHJ_01285 1.14e-199 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 phosphate
PGOAFCHJ_01286 8.58e-316 rsmF - - J - - - NOL1 NOP2 sun family protein
PGOAFCHJ_01287 1.37e-176 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
PGOAFCHJ_01288 3.43e-59 yktA - - S - - - Belongs to the UPF0223 family
PGOAFCHJ_01289 3.58e-93 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PGOAFCHJ_01290 5.78e-215 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PGOAFCHJ_01291 9.7e-185 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGOAFCHJ_01292 0.0 XK27_04775 - - S ko:K09155 - ko00000 hemerythrin HHE cation binding domain
PGOAFCHJ_01293 7.18e-47 M1-755 - - P ko:K09155 - ko00000 Hemerythrin HHE cation binding domain protein
PGOAFCHJ_01294 5.72e-144 hsdS2 - - V - - - Type I restriction modification DNA specificity domain
PGOAFCHJ_01295 8.23e-112 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGOAFCHJ_01296 3.67e-176 - - - S - - - haloacid dehalogenase-like hydrolase
PGOAFCHJ_01297 5.71e-305 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 o-acetylhomoserine
PGOAFCHJ_01298 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PGOAFCHJ_01299 1.43e-306 agcS - - E ko:K03310 - ko00000 (Alanine) symporter
PGOAFCHJ_01300 6.62e-312 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGOAFCHJ_01301 4.69e-226 bglC - - K - - - Transcriptional regulator
PGOAFCHJ_01302 0.0 sasH 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PGOAFCHJ_01303 3.26e-105 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01304 3.96e-191 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PGOAFCHJ_01305 2.23e-303 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
PGOAFCHJ_01306 3.05e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGOAFCHJ_01307 1.44e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PGOAFCHJ_01308 1.61e-224 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PGOAFCHJ_01309 3.14e-185 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PGOAFCHJ_01310 1.38e-121 thiJ 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
PGOAFCHJ_01311 9.17e-173 - - - S - - - TraX protein
PGOAFCHJ_01312 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PGOAFCHJ_01313 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
PGOAFCHJ_01314 5.02e-295 dinF - - V - - - Mate efflux family protein
PGOAFCHJ_01315 5.63e-227 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type enterochelin transport system, periplasmic component
PGOAFCHJ_01316 0.0 - - - V - - - Type III restriction enzyme, res subunit
PGOAFCHJ_01317 9.39e-141 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 HAD hydrolase, family IA, variant 1
PGOAFCHJ_01318 2.46e-171 - - - F - - - Phosphorylase superfamily
PGOAFCHJ_01320 7.19e-237 adhB 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
PGOAFCHJ_01321 2.06e-253 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PGOAFCHJ_01322 3.68e-203 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
PGOAFCHJ_01323 3.27e-123 - - - K - - - Transcriptional regulator, TetR family
PGOAFCHJ_01324 1e-90 - - - S - - - Protein of unknown function with HXXEE motif
PGOAFCHJ_01326 1.6e-176 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
PGOAFCHJ_01327 1.12e-177 - - - S - - - Phenazine biosynthesis protein
PGOAFCHJ_01328 1.27e-119 tetR - - K - - - transcriptional regulator
PGOAFCHJ_01329 5.41e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01330 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01331 2.55e-46 - - - L ko:K07497 - ko00000 Integrase core domain protein
PGOAFCHJ_01332 6.92e-141 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
PGOAFCHJ_01333 0.0 proWX - - P ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGOAFCHJ_01334 7.08e-165 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
PGOAFCHJ_01335 1.09e-189 - 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 epimerase
PGOAFCHJ_01336 6.72e-97 - - - K - - - Transcriptional regulator, MarR family
PGOAFCHJ_01337 2.8e-73 - - - S - - - Macro domain protein
PGOAFCHJ_01339 2.34e-114 - - - K - - - COG COG0846 NAD-dependent protein deacetylases, SIR2 family
PGOAFCHJ_01340 5.62e-15 - - - C - - - Pyridoxamine 5'-phosphate oxidase family protein
PGOAFCHJ_01341 7.74e-172 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
PGOAFCHJ_01342 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PGOAFCHJ_01345 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PGOAFCHJ_01347 5.4e-175 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 Acetoin reductase
PGOAFCHJ_01348 1.08e-57 - - - P - - - Rhodanese-like protein
PGOAFCHJ_01349 1.8e-94 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PGOAFCHJ_01350 4.5e-284 XK27_05470 - - E - - - Methionine synthase
PGOAFCHJ_01351 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PGOAFCHJ_01352 6.77e-287 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PGOAFCHJ_01353 9.43e-154 yycF1 - - T ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGOAFCHJ_01355 1.16e-69 - - - V ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PGOAFCHJ_01356 5.15e-107 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PGOAFCHJ_01357 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGOAFCHJ_01358 4.71e-202 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
PGOAFCHJ_01359 3.46e-213 - - - GK - - - ROK family
PGOAFCHJ_01360 5.35e-53 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGOAFCHJ_01361 4.94e-102 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGOAFCHJ_01362 1.4e-201 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGOAFCHJ_01363 4.32e-164 - - - K - - - DNA-binding helix-turn-helix protein
PGOAFCHJ_01364 2.73e-118 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
PGOAFCHJ_01365 1.33e-111 - - - - ko:K16788 - ko00000,ko02000 -
PGOAFCHJ_01366 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGOAFCHJ_01367 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PGOAFCHJ_01368 5.01e-160 yvoA_2 - - K ko:K03710 - ko00000,ko03000 transcriptional
PGOAFCHJ_01369 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PGOAFCHJ_01370 5.51e-127 - - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGOAFCHJ_01371 2.84e-240 adhP 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
PGOAFCHJ_01372 5.93e-60 - - - - - - - -
PGOAFCHJ_01373 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGOAFCHJ_01374 3.05e-200 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PGOAFCHJ_01375 1.24e-144 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01376 1.17e-135 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01377 4.11e-77 phnA - - P ko:K06193 ko01120,map01120 ko00000 Alkylphosphonate utilization operon protein PhnA
PGOAFCHJ_01378 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGOAFCHJ_01379 2.09e-212 cpsY - - K - - - Transcriptional regulator
PGOAFCHJ_01380 2.29e-163 - - CBM50 NU ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 muramidase
PGOAFCHJ_01381 1.38e-213 yeiH - - S - - - Membrane
PGOAFCHJ_01384 0.0 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PGOAFCHJ_01385 3.37e-183 XK27_10720 - - D - - - peptidase activity
PGOAFCHJ_01386 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
PGOAFCHJ_01387 4.01e-206 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PGOAFCHJ_01388 5.25e-233 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PGOAFCHJ_01389 1.03e-209 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PGOAFCHJ_01390 1.48e-173 yejC - - S - - - cyclic nucleotide-binding protein
PGOAFCHJ_01391 1.81e-316 - - - D - - - nuclear chromosome segregation
PGOAFCHJ_01392 1.61e-122 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PGOAFCHJ_01393 3.04e-173 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PGOAFCHJ_01394 4.24e-108 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
PGOAFCHJ_01395 6.43e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PGOAFCHJ_01396 3.71e-83 aldR 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
PGOAFCHJ_01398 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PGOAFCHJ_01399 6.82e-273 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PGOAFCHJ_01400 1.32e-106 ypmB - - S - - - Protein conserved in bacteria
PGOAFCHJ_01401 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PGOAFCHJ_01402 5.27e-147 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
PGOAFCHJ_01403 5.77e-218 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGOAFCHJ_01404 1.53e-243 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGOAFCHJ_01405 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGOAFCHJ_01406 7.49e-240 - - - S ko:K07335 - ko00000 membrane
PGOAFCHJ_01407 2.46e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PGOAFCHJ_01408 1.2e-139 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGOAFCHJ_01409 2.8e-296 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PGOAFCHJ_01410 3.21e-136 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase small domain protein
PGOAFCHJ_01411 4.78e-220 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PGOAFCHJ_01412 4.36e-40 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PGOAFCHJ_01413 5.01e-310 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGOAFCHJ_01414 2.39e-154 ciaR - - T ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGOAFCHJ_01415 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
PGOAFCHJ_01416 2.77e-150 coaB 6.3.2.5 - H ko:K21977 ko00770,map00770 ko00000,ko00001,ko00002,ko01000 Phosphopantothenate-cysteine ligase
PGOAFCHJ_01417 1.43e-118 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGOAFCHJ_01418 1.24e-119 - - - S - - - ECF transporter, substrate-specific component
PGOAFCHJ_01419 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
PGOAFCHJ_01420 4.05e-209 metF 1.5.1.20 - E ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 reductase
PGOAFCHJ_01421 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PGOAFCHJ_01423 0.0 pabB 2.6.1.85, 4.1.3.38 - EH ko:K01665,ko:K03342,ko:K13950 ko00790,map00790 ko00000,ko00001,ko01000,ko01007 component I
PGOAFCHJ_01424 0.0 - 3.6.3.2, 3.6.3.6, 3.6.3.8 - P ko:K01531,ko:K01535,ko:K01537 ko00190,map00190 ko00000,ko00001,ko01000 cation transport ATPase
PGOAFCHJ_01425 2.87e-307 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGOAFCHJ_01426 7.07e-48 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGOAFCHJ_01427 2.07e-301 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Membrane protein involved in D-alanine export
PGOAFCHJ_01428 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGOAFCHJ_01429 0.0 XK27_10035 - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01430 0.0 yfiB1 - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01431 1.77e-127 pvaA - - M ko:K02395 - ko00000,ko02035 lytic transglycosylase activity
PGOAFCHJ_01432 3.67e-229 - - - S - - - 37-kD nucleoid-associated bacterial protein
PGOAFCHJ_01433 3.65e-291 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGOAFCHJ_01434 4.33e-134 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PGOAFCHJ_01435 5.82e-186 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PGOAFCHJ_01436 4.58e-247 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGOAFCHJ_01437 5.81e-141 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PGOAFCHJ_01438 3.42e-235 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PGOAFCHJ_01439 3.06e-194 gst - - O ko:K11209 - ko00000,ko01000 Glutathione S-transferase
PGOAFCHJ_01440 5.01e-226 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
PGOAFCHJ_01441 3.37e-222 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PGOAFCHJ_01442 3.52e-61 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 50S ribosomal protein L31
PGOAFCHJ_01443 1.49e-292 mntH_2 - - P - - - Mn2 and Fe2 transporters of the NRAMP family
PGOAFCHJ_01444 8.99e-208 ypuA - - S - - - secreted protein
PGOAFCHJ_01445 1.83e-94 ywkD - - E ko:K08234 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PGOAFCHJ_01446 2.55e-168 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase (surface protein transpeptidase)
PGOAFCHJ_01447 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGOAFCHJ_01448 2.06e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PGOAFCHJ_01449 0.0 noxE - - P - - - NADH oxidase
PGOAFCHJ_01450 0.0 yheS_1 - - S - - - abc transporter atp-binding protein
PGOAFCHJ_01451 7.32e-105 - - - S - - - ECF-type riboflavin transporter, S component
PGOAFCHJ_01452 9.21e-171 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Belongs to the pyridoxine kinase family
PGOAFCHJ_01453 5.05e-104 - - - S - - - ECF-type riboflavin transporter, S component
PGOAFCHJ_01455 1.57e-267 ycxD - - K - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGOAFCHJ_01456 6.52e-75 nrdD_1 1.1.98.6, 1.17.4.1 - F ko:K00525,ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Ribonucleoside-triphosphate reductase
PGOAFCHJ_01458 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGOAFCHJ_01459 6.18e-120 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGOAFCHJ_01460 1.96e-251 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGOAFCHJ_01461 3.7e-32 WQ51_00220 - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix domain
PGOAFCHJ_01462 2.4e-101 - - - S - - - Protein of unknown function (DUF3278)
PGOAFCHJ_01463 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PGOAFCHJ_01464 2.16e-159 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PGOAFCHJ_01465 1.81e-222 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGOAFCHJ_01466 2.49e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGOAFCHJ_01467 2.24e-160 - - - L - - - DNA alkylation repair enzyme
PGOAFCHJ_01468 0.0 clsA_1 - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGOAFCHJ_01469 6.46e-121 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase
PGOAFCHJ_01470 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGOAFCHJ_01471 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
PGOAFCHJ_01472 2.01e-69 - - - - - - - -
PGOAFCHJ_01473 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGOAFCHJ_01474 3.55e-164 yfnB 3.8.1.2 - E ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 hydrolase
PGOAFCHJ_01475 4.47e-154 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PGOAFCHJ_01476 1.12e-189 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PGOAFCHJ_01477 0.0 - 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PGOAFCHJ_01478 1.51e-207 yjlA - - EG - - - membrane
PGOAFCHJ_01479 9.81e-105 - - - S - - - RDD family
PGOAFCHJ_01480 1.16e-27 - - - - - - - -
PGOAFCHJ_01481 1.51e-19 - - - - - - - -
PGOAFCHJ_01482 1.14e-110 - - - - - - - -
PGOAFCHJ_01483 0.000123 - - - - - - - -
PGOAFCHJ_01484 2.32e-99 - - - K - - - Acetyltransferase (GNAT) domain
PGOAFCHJ_01485 3.14e-182 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PGOAFCHJ_01486 1.16e-178 M1-956 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PGOAFCHJ_01487 9.12e-237 - - - S ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PGOAFCHJ_01488 5.21e-105 - - - - - - - -
PGOAFCHJ_01491 1.05e-112 yfjR - - K - - - regulation of single-species biofilm formation
PGOAFCHJ_01492 7.36e-153 - - - S - - - Protein of unknown function DUF262
PGOAFCHJ_01493 2.63e-257 - - - S - - - Protein of unknown function DUF262
PGOAFCHJ_01494 1.4e-132 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGOAFCHJ_01495 1.7e-240 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGOAFCHJ_01496 4.12e-170 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
PGOAFCHJ_01497 1.45e-203 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 'abc transporter, ATP-binding protein
PGOAFCHJ_01501 4.82e-254 anK3 - - G ko:K07126 - ko00000 response to abiotic stimulus
PGOAFCHJ_01502 0.0 hscC - - O ko:K04045 - ko00000,ko03110 Belongs to the heat shock protein 70 family
PGOAFCHJ_01503 1.45e-210 yocS - - S ko:K03453 - ko00000 Transporter
PGOAFCHJ_01504 4.74e-106 - - - F - - - cytidine deaminase activity
PGOAFCHJ_01505 2.2e-149 - - - V ko:K01992 - ko00000,ko00002,ko02000 Transporter
PGOAFCHJ_01506 8.41e-203 XK27_09825 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01509 1.67e-120 XK27_05000 - - S ko:K06940 - ko00000 metal cluster binding
PGOAFCHJ_01510 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
PGOAFCHJ_01511 1.49e-171 yxdL - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PGOAFCHJ_01512 5.9e-198 - - - T - - - Histidine kinase
PGOAFCHJ_01513 3.69e-159 graR - - KT ko:K19082 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGOAFCHJ_01514 1.03e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PGOAFCHJ_01515 5.96e-284 pbuX - - F ko:K16169 - ko00000,ko02000 xanthine permease
PGOAFCHJ_01516 0.0 - - - V ko:K06148 - ko00000,ko02000 (ABC) transporter
PGOAFCHJ_01517 7.92e-184 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 sequence-specific DNA binding
PGOAFCHJ_01518 3.83e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PGOAFCHJ_01520 2.12e-227 msrA 1.8.4.11, 1.8.4.12 - O ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGOAFCHJ_01522 1.39e-38 - - - T - - - A nuclease of the HNH/ENDO VII superfamily with conserved WHH
PGOAFCHJ_01523 0.0 - - - S - - - Domain of unknown function DUF87
PGOAFCHJ_01524 1.89e-150 - - - T - - - ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGOAFCHJ_01525 8.28e-292 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PGOAFCHJ_01526 8.71e-231 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PGOAFCHJ_01528 6.76e-132 - - - V ko:K02004,ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score
PGOAFCHJ_01529 8.68e-125 - - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC-type antimicrobial peptide transport system, ATPase component
PGOAFCHJ_01530 1.44e-160 - - - S - - - TraX protein
PGOAFCHJ_01531 7.08e-104 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
PGOAFCHJ_01532 1.66e-92 - - - T - - - response regulator receiver
PGOAFCHJ_01534 2.37e-200 - - - S - - - DUF218 domain
PGOAFCHJ_01535 1.91e-62 B4168_4126 - - L ko:K07493 - ko00000 High confidence in function and specificity
PGOAFCHJ_01536 7.73e-83 - - - S - - - Protein of unknown function (DUF3290)
PGOAFCHJ_01537 9.34e-136 - - - S - - - Protein of unknown function (DUF421)
PGOAFCHJ_01538 2.15e-27 csbD - - K - - - CsbD-like
PGOAFCHJ_01539 2.85e-213 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
PGOAFCHJ_01540 1.12e-34 - - - S - - - Carbohydrate-binding domain-containing protein Cthe_2159
PGOAFCHJ_01541 3.99e-65 - - - S - - - ASCH
PGOAFCHJ_01542 3.1e-292 yfnA - - E ko:K03294 - ko00000 amino acid
PGOAFCHJ_01543 0.0 - - - S - - - dextransucrase activity
PGOAFCHJ_01545 5.4e-175 tcyC2 - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01546 3.2e-145 - - - P ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
PGOAFCHJ_01547 2.25e-146 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01548 9.58e-211 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PGOAFCHJ_01549 3.77e-225 - 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen decarboxylase (URO-D)
PGOAFCHJ_01550 4.8e-109 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PGOAFCHJ_01551 1.97e-56 - - - S - - - Sugar efflux transporter for intercellular exchange
PGOAFCHJ_01552 6.33e-256 - - - P ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
PGOAFCHJ_01553 5.24e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01554 6.56e-126 - - - K - - - WHG domain
PGOAFCHJ_01555 6.47e-214 ydhF - - S - - - Aldo keto reductase
PGOAFCHJ_01557 9.79e-37 XK27_07105 - - K ko:K07729 - ko00000,ko03000 transcriptional
PGOAFCHJ_01558 3.18e-46 - - - - - - - -
PGOAFCHJ_01559 7.85e-139 XK27_02070 - - S ko:K07078 - ko00000 nitroreductase
PGOAFCHJ_01560 2.82e-197 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
PGOAFCHJ_01561 7.28e-101 ywnA_2 - - K - - - Transcriptional regulator
PGOAFCHJ_01562 1.98e-198 - - - E - - - Alpha/beta hydrolase of unknown function (DUF915)
PGOAFCHJ_01563 1.84e-282 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGOAFCHJ_01564 1.08e-216 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01565 3.33e-163 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PGOAFCHJ_01566 2.12e-57 - - - S - - - Domain of unknown function (DUF4352)
PGOAFCHJ_01567 1.25e-171 - - - T - - - His Kinase A (phosphoacceptor) domain
PGOAFCHJ_01568 5.05e-162 - - - T - - - Xre family transcriptional regulator
PGOAFCHJ_01569 1.06e-141 yodC - - C - - - nitroreductase
PGOAFCHJ_01570 2.41e-140 - - - S - - - Protein of unknown function (DUF1275)
PGOAFCHJ_01571 8.33e-53 - - - DJ ko:K06218 - ko00000,ko02048 nuclease activity
PGOAFCHJ_01572 1.47e-41 XK27_10490 - - - - - - -
PGOAFCHJ_01573 4.36e-203 yvgN - - C - - - reductase
PGOAFCHJ_01574 5.55e-244 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PGOAFCHJ_01575 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 COG0366 Glycosidases
PGOAFCHJ_01576 2.92e-281 vncS 2.7.13.3 - T ko:K10819 - ko00000,ko01000 Histidine kinase
PGOAFCHJ_01577 3.03e-149 vncR - - K - - - Response regulator receiver domain protein
PGOAFCHJ_01578 7.9e-305 vex3 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
PGOAFCHJ_01579 2.14e-141 vex2 - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01580 1.21e-270 vex1 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
PGOAFCHJ_01581 0.0 XK27_07020 - - S - - - Belongs to the UPF0371 family
PGOAFCHJ_01582 1.52e-06 - - - - - - - -
PGOAFCHJ_01583 9.29e-255 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 glycerol dehydrogenase
PGOAFCHJ_01584 8.66e-229 XK27_10475 - - S - - - oxidoreductase
PGOAFCHJ_01585 2e-77 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 dihydroxyacetone kinase, phosphotransfer subunit
PGOAFCHJ_01586 2.24e-120 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
PGOAFCHJ_01587 1.44e-228 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dihydroxyacetone kinase
PGOAFCHJ_01588 1.65e-285 - - - K - - - Psort location CytoplasmicMembrane, score
PGOAFCHJ_01589 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01590 1.25e-46 - - - S - - - Immunity protein 41
PGOAFCHJ_01591 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
PGOAFCHJ_01592 2.78e-12 - - - S - - - Enterocin A Immunity
PGOAFCHJ_01593 2.37e-246 mccF - - V - - - LD-carboxypeptidase
PGOAFCHJ_01594 2.93e-14 - - - S - - - integral membrane protein
PGOAFCHJ_01595 7.02e-58 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PGOAFCHJ_01596 1.62e-151 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
PGOAFCHJ_01597 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
PGOAFCHJ_01598 0.0 - - - S - - - dextransucrase activity
PGOAFCHJ_01599 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
PGOAFCHJ_01600 4.11e-71 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01602 1.37e-304 - - - S - - - dextransucrase activity
PGOAFCHJ_01603 1.24e-299 - - - S - - - dextransucrase activity
PGOAFCHJ_01604 3.71e-98 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01605 0.0 - - - S - - - dextransucrase activity
PGOAFCHJ_01606 1.11e-132 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PGOAFCHJ_01607 8.33e-200 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PGOAFCHJ_01608 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01609 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01610 0.0 - - - S - - - dextransucrase activity
PGOAFCHJ_01611 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01612 7.19e-242 - - - S - - - dextransucrase activity
PGOAFCHJ_01613 0.0 - - - S - - - dextransucrase activity
PGOAFCHJ_01614 0.0 tcdB - - M ko:K11063 ko02024,map02024 ko00000,ko00001,ko02042 Putative cell wall binding repeat
PGOAFCHJ_01615 3.39e-291 - - - S - - - dextransucrase activity
PGOAFCHJ_01617 5.18e-172 - - - S - - - CAAX protease self-immunity
PGOAFCHJ_01618 2.35e-303 - - - EGP ko:K18926 - ko00000,ko00002,ko02000 Major facilitator Superfamily
PGOAFCHJ_01619 1.46e-87 - - - K - - - Transcriptional regulator, MarR family
PGOAFCHJ_01620 5.37e-126 maa 2.3.1.79 - GK ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
PGOAFCHJ_01621 3.78e-168 - - - S - - - N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
PGOAFCHJ_01622 0.0 - 3.5.1.28 - M ko:K01448,ko:K13733,ko:K20276 ko01503,ko02024,ko05100,map01503,map02024,map05100 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 domain protein
PGOAFCHJ_01623 0.0 - 2.4.1.5 GH13 M ko:K00689 ko00500,ko02020,map00500,map02020 ko00000,ko00001,ko01000 KxYKxGKxW signal domain protein
PGOAFCHJ_01624 1.06e-31 - - - - - - - -
PGOAFCHJ_01628 9.97e-85 sraP - - UW ko:K18491,ko:K21449 ko04550,map04550 ko00000,ko00001,ko02000,ko03000 Hep Hag repeat protein
PGOAFCHJ_01629 0.0 sraP - - UW ko:K18491,ko:K21449 ko04550,map04550 ko00000,ko00001,ko02000,ko03000 Hep Hag repeat protein
PGOAFCHJ_01630 9.2e-243 - - - M - - - transferase activity, transferring glycosyl groups
PGOAFCHJ_01631 3.67e-23 - - - S - - - Accessory secretory protein Sec, Asp5
PGOAFCHJ_01632 3.27e-24 - - - S - - - Accessory secretory protein Sec Asp4
PGOAFCHJ_01633 8.01e-310 gtf2 - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PGOAFCHJ_01634 0.0 gtf1 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PGOAFCHJ_01635 0.0 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGOAFCHJ_01636 2.01e-102 asp3 - - S ko:K12270 - ko00000,ko02044 Accessory Sec system protein Asp3
PGOAFCHJ_01637 0.0 asp2 - - S ko:K12269 - ko00000,ko02044 Accessory Sec system protein Asp2
PGOAFCHJ_01638 0.0 asp1 - - S ko:K12268 - ko00000,ko02044 Accessory Sec system protein Asp1
PGOAFCHJ_01639 2.44e-269 secY2 - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the accessory SecA2 SecY2 system specifically required for export of
PGOAFCHJ_01640 0.0 - - - M - - - family 8
PGOAFCHJ_01641 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 ATPase involved in DNA repair
PGOAFCHJ_01642 1.91e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PGOAFCHJ_01643 0.0 - - - GM - - - domain, Protein
PGOAFCHJ_01644 0.0 - - - M ko:K08643 - ko00000,ko01000,ko01002 signal peptide protein, YSIRK family
PGOAFCHJ_01645 0.0 - - - M - - - Rib/alpha-like repeat
PGOAFCHJ_01646 0.0 - - - M - - - domain protein
PGOAFCHJ_01647 1.71e-09 - - - - - - - -
PGOAFCHJ_01649 2.07e-240 XK27_10075 - - S - - - abc transporter atp-binding protein
PGOAFCHJ_01650 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01651 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01652 0.0 gshF 6.3.2.2 - H ko:K01919,ko:K16786,ko:K16787 ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the glutamate--cysteine ligase type 1 family
PGOAFCHJ_01654 0.0 - - - S - - - Protein of unknown function (DUF3114)
PGOAFCHJ_01655 1.49e-127 - - - K - - - Acetyltransferase GNAT Family
PGOAFCHJ_01656 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PGOAFCHJ_01657 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
PGOAFCHJ_01658 2.81e-230 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 glucose-1-phosphate adenylyltransferase
PGOAFCHJ_01659 1.04e-249 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PGOAFCHJ_01660 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PGOAFCHJ_01661 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
PGOAFCHJ_01662 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PGOAFCHJ_01663 6.99e-242 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PGOAFCHJ_01664 1.98e-174 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PGOAFCHJ_01665 9.14e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGOAFCHJ_01668 2.7e-146 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGOAFCHJ_01669 1.2e-219 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGOAFCHJ_01670 8.54e-152 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Membrane
PGOAFCHJ_01671 1.63e-139 - - - P ko:K10716 - ko00000,ko02000 Ion transport protein
PGOAFCHJ_01672 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PGOAFCHJ_01673 7.36e-173 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PGOAFCHJ_01674 2.59e-311 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGOAFCHJ_01675 8.23e-219 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGOAFCHJ_01676 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGOAFCHJ_01677 1.37e-61 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-directed 5'-3' RNA polymerase activity
PGOAFCHJ_01678 4.34e-145 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PGOAFCHJ_01679 1.76e-277 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PGOAFCHJ_01680 2.19e-183 XK27_02985 - - S - - - overlaps another CDS with the same product name
PGOAFCHJ_01681 2.49e-185 - - - S - - - overlaps another CDS with the same product name
PGOAFCHJ_01682 8.13e-82 ytrA - - K ko:K07979 - ko00000,ko03000 Transcriptional
PGOAFCHJ_01683 3.38e-158 skfE - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01684 3.17e-166 - - - V - - - Psort location CytoplasmicMembrane, score
PGOAFCHJ_01685 5.55e-216 amiF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGOAFCHJ_01686 4.47e-255 amiE - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGOAFCHJ_01687 2.24e-210 amiD - - P ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01688 0.0 amiC - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01689 0.0 amiA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PGOAFCHJ_01690 0.0 amiA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
PGOAFCHJ_01691 1.87e-223 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
PGOAFCHJ_01692 7.06e-218 yjbO 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PGOAFCHJ_01693 5.67e-196 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGOAFCHJ_01694 5.79e-154 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 Gtp pyrophosphokinase
PGOAFCHJ_01695 1.59e-129 yjbK - - S - - - Adenylate cyclase
PGOAFCHJ_01696 1.67e-224 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGOAFCHJ_01697 3.73e-263 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PGOAFCHJ_01698 1.52e-79 XK27_04120 - - S - - - Putative amino acid metabolism
PGOAFCHJ_01699 7.44e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGOAFCHJ_01700 2.91e-163 - - - T ko:K07010 - ko00000,ko01002 peptidase C26
PGOAFCHJ_01701 2.67e-153 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PGOAFCHJ_01702 0.0 rgpF - - M ko:K07272 - ko00000,ko01000,ko01003,ko01005 Rhamnan synthesis protein F
PGOAFCHJ_01703 1.29e-234 rgpEc - GT2 M ko:K12998 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
PGOAFCHJ_01704 9.53e-284 rgpD 3.6.3.40 - P ko:K01990,ko:K09691,ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PGOAFCHJ_01705 4.1e-182 rgpC - - GM ko:K01992 - ko00000,ko00002,ko02000 Transport permease protein
PGOAFCHJ_01706 1.96e-225 rgpB - GT2 M ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
PGOAFCHJ_01707 7.32e-273 rgpA - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
PGOAFCHJ_01708 9.86e-170 - - - S - - - Predicted membrane protein (DUF2142)
PGOAFCHJ_01709 7.63e-227 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
PGOAFCHJ_01710 2.03e-274 rgpX3 - - S - - - polysaccharide biosynthetic process
PGOAFCHJ_01711 2.12e-61 - - - S ko:K09153 - ko00000 Uncharacterized conserved protein (DUF2304)
PGOAFCHJ_01712 1.14e-159 - - - S - - - Glycosyl transferase family 2
PGOAFCHJ_01713 1.16e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PGOAFCHJ_01714 1.54e-217 yfdH - GT2 M ko:K12999,ko:K20534 - ko00000,ko01000,ko01003,ko01005,ko02000 COG0463, glycosyltransferases involved in cell wall biogenesis
PGOAFCHJ_01715 1.43e-73 yitW - - K - - - metal-sulfur cluster biosynthetic enzyme
PGOAFCHJ_01716 2.49e-256 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PGOAFCHJ_01717 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PGOAFCHJ_01718 2.93e-65 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PGOAFCHJ_01719 8.61e-28 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PGOAFCHJ_01720 2.45e-176 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PGOAFCHJ_01721 3.91e-269 arcT - - E - - - Aminotransferase
PGOAFCHJ_01722 1.32e-178 - - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PGOAFCHJ_01723 2.1e-180 XK27_04395 - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter
PGOAFCHJ_01724 3.05e-109 XK27_04400 3.6.1.55 - F ko:K03574,ko:K12944 - ko00000,ko01000,ko03400 Nudix family
PGOAFCHJ_01725 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PGOAFCHJ_01727 8.1e-210 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
PGOAFCHJ_01728 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type amino acid transport signal transduction systems periplasmic component domain
PGOAFCHJ_01729 5.64e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01730 5.23e-25 XK27_00735 - - - - - - -
PGOAFCHJ_01731 2.23e-314 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGOAFCHJ_01732 9.86e-10 - - - S - - - Protein of unknown function (DUF4044)
PGOAFCHJ_01733 1.68e-168 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PGOAFCHJ_01734 4.89e-09 - - - O - - - ADP-ribosylglycohydrolase
PGOAFCHJ_01735 1.99e-82 - - - Q ko:K02614 ko00360,map00360 ko00000,ko00001,ko01000 protein possibly involved in aromatic compounds catabolism
PGOAFCHJ_01736 7.06e-81 ycaO - - O ko:K06889,ko:K07397,ko:K09136 - ko00000,ko03009 OsmC-like protein
PGOAFCHJ_01738 2.25e-188 - - - EG - - - Permeases of the drug metabolite transporter (DMT) superfamily
PGOAFCHJ_01740 8.02e-144 serB 3.1.3.3 - E ko:K01079 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01009 phosphoserine phosphatase
PGOAFCHJ_01741 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PGOAFCHJ_01742 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGOAFCHJ_01743 1.83e-120 - - - S - - - IA, variant 1
PGOAFCHJ_01744 5.34e-150 lrgB - - M - - - Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PGOAFCHJ_01745 5.9e-74 lrgA - - S ko:K06518 - ko00000,ko02000 Effector of murein hydrolase LrgA
PGOAFCHJ_01747 1.85e-85 ogt 2.1.1.63, 3.2.2.20 - L ko:K00567,ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 methylated-DNA-[protein]-cysteine S-methyltransferase activity
PGOAFCHJ_01748 2.5e-277 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGOAFCHJ_01749 1.62e-135 - - - M - - - Acetyltransferase (GNAT) domain
PGOAFCHJ_01750 8.49e-266 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PGOAFCHJ_01751 7.14e-202 - - - GK - - - ROK family
PGOAFCHJ_01752 2.36e-93 gloA 4.4.1.5 - E ko:K01759,ko:K15772 ko00620,ko02010,map00620,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Lactoylglutathione lyase
PGOAFCHJ_01753 4.79e-196 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 HflC and HflK could regulate a protease
PGOAFCHJ_01754 4.51e-261 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 spermidine putrescine ABC transporter
PGOAFCHJ_01755 8.8e-167 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component II
PGOAFCHJ_01756 4.03e-179 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
PGOAFCHJ_01757 4.41e-269 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PGOAFCHJ_01758 9.27e-215 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
PGOAFCHJ_01759 3.96e-107 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PGOAFCHJ_01760 5.86e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGOAFCHJ_01761 0.0 amy 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PGOAFCHJ_01762 1.44e-185 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PGOAFCHJ_01763 4.02e-129 folE 3.5.4.16 - F ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 gtp cyclohydrolase
PGOAFCHJ_01764 0.0 ydaO - - E - - - amino acid
PGOAFCHJ_01765 1.07e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PGOAFCHJ_01766 3.71e-49 ylqC - - L ko:K06960 - ko00000 Belongs to the UPF0109 family
PGOAFCHJ_01767 1.87e-57 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PGOAFCHJ_01768 0.000134 yebC - - M - - - Membrane
PGOAFCHJ_01769 4.23e-258 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_01770 1.65e-160 agrA - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 phosphorelay signal transduction system
PGOAFCHJ_01771 2.09e-236 - - - O - - - protein import
PGOAFCHJ_01772 9.6e-213 tehB 2.1.1.265 - PQ ko:K16868 - ko00000,ko01000 tellurite resistance protein tehb
PGOAFCHJ_01773 3.71e-15 yjdB - - S - - - Domain of unknown function (DUF4767)
PGOAFCHJ_01774 4.81e-253 XK27_00915 - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGOAFCHJ_01776 5.11e-204 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PGOAFCHJ_01777 1.36e-94 - - - S - - - QueT transporter
PGOAFCHJ_01779 8.31e-228 yfjR - - K - - - regulation of single-species biofilm formation
PGOAFCHJ_01781 2.05e-232 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PGOAFCHJ_01782 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGOAFCHJ_01783 1.71e-111 ccl - - S - - - cog cog4708
PGOAFCHJ_01784 1.1e-208 rbn - - E ko:K07058 - ko00000 Belongs to the UPF0761 family
PGOAFCHJ_01785 2.01e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PGOAFCHJ_01786 7.45e-296 ytoI - - K - - - transcriptional regulator containing CBS domains
PGOAFCHJ_01787 1.44e-127 XK27_07830 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase GNAT Family
PGOAFCHJ_01788 6.07e-292 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGOAFCHJ_01789 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PGOAFCHJ_01790 7.27e-132 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
PGOAFCHJ_01791 2.5e-183 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
PGOAFCHJ_01792 4.51e-203 nodB3 - - G - - - deacetylase
PGOAFCHJ_01793 3.54e-180 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase
PGOAFCHJ_01794 1.33e-52 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
PGOAFCHJ_01795 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PGOAFCHJ_01796 2.22e-202 corA - - P - - - CorA-like protein
PGOAFCHJ_01797 1.51e-82 yjqA - - S - - - Bacterial PH domain
PGOAFCHJ_01798 5.34e-128 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter
PGOAFCHJ_01799 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PGOAFCHJ_01800 1.75e-150 ywaF - - S - - - Integral membrane protein (intg_mem_TP0381)
PGOAFCHJ_01801 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PGOAFCHJ_01805 1.1e-198 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
PGOAFCHJ_01806 5.18e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01807 4.6e-148 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01808 7.05e-148 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01809 1.53e-244 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PGOAFCHJ_01810 5.6e-42 copZ - - P - - - Heavy metal-associated domain protein
PGOAFCHJ_01811 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PGOAFCHJ_01812 3.52e-96 copY - - K - - - negative regulation of transcription, DNA-templated
PGOAFCHJ_01813 9.68e-224 - - - EGP ko:K08218 ko01501,map01501 ko00000,ko00001,ko00002,ko02000 Major facilitator Superfamily
PGOAFCHJ_01816 3.54e-183 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PGOAFCHJ_01817 4.77e-289 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PGOAFCHJ_01818 3.76e-129 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the TrpF family
PGOAFCHJ_01819 7.94e-173 trpC 4.1.1.48 - E ko:K01609 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PGOAFCHJ_01820 5.2e-229 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PGOAFCHJ_01821 1.67e-134 trpG 4.1.3.27 - EH ko:K01658 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 anthranilate
PGOAFCHJ_01822 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGOAFCHJ_01823 2.94e-53 MA20_20425 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 - E ko:K00800,ko:K03785,ko:K04092,ko:K04782 ko00400,ko01053,ko01100,ko01110,ko01130,ko01230,map00400,map01053,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Chorismate mutase
PGOAFCHJ_01824 1.37e-78 - - - - - - - -
PGOAFCHJ_01825 0.0 ctpE - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
PGOAFCHJ_01826 2.7e-60 - - - - - - - -
PGOAFCHJ_01827 8.82e-58 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PGOAFCHJ_01829 4.56e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01830 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01831 1.95e-162 - - - K - - - transcriptional regulator, MerR family
PGOAFCHJ_01832 1.26e-133 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PGOAFCHJ_01833 5.18e-76 WQ51_02910 - - S - - - Protein of unknown function, DUF536
PGOAFCHJ_01834 1.81e-82 XK27_02560 - - S - - - cog cog2151
PGOAFCHJ_01835 0.0 ilvD 4.2.1.9 - E ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
PGOAFCHJ_01836 1.52e-272 ytfP - - S ko:K07007 - ko00000 Flavoprotein
PGOAFCHJ_01837 5.29e-95 - - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
PGOAFCHJ_01839 1.25e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PGOAFCHJ_01840 2.95e-197 ytmP - - M - - - Phosphotransferase
PGOAFCHJ_01841 1.93e-219 XK27_05910 - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
PGOAFCHJ_01842 1.38e-167 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01843 3.05e-95 hit - - FG ko:K02503 - ko00000,ko04147 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PGOAFCHJ_01847 1.98e-133 - - - - - - - -
PGOAFCHJ_01849 0.0 clpL - - O ko:K04086 - ko00000,ko03110 ATP-dependent Clp protease ATP-binding subunit
PGOAFCHJ_01852 6.81e-251 ylbM - - S - - - Belongs to the UPF0348 family
PGOAFCHJ_01853 3.69e-178 XK27_06665 - - Q - - - Methyltransferase domain protein
PGOAFCHJ_01854 3.42e-77 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PGOAFCHJ_01855 3.9e-137 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
PGOAFCHJ_01856 6.44e-152 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGOAFCHJ_01857 4.57e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
PGOAFCHJ_01858 2.1e-270 yqeH - - S ko:K06948 - ko00000,ko03009 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PGOAFCHJ_01859 1.29e-127 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
PGOAFCHJ_01860 7.77e-44 - - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGOAFCHJ_01861 3.89e-242 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PGOAFCHJ_01862 6.39e-80 - - - - - - - -
PGOAFCHJ_01863 1.22e-280 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGOAFCHJ_01864 1.96e-73 - - - - - - - -
PGOAFCHJ_01865 5.56e-52 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
PGOAFCHJ_01866 0.0 celR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PGOAFCHJ_01867 4.78e-62 celB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
PGOAFCHJ_01868 2.58e-41 - - - S ko:K15383 - ko00000,ko02000 PQ loop repeat
PGOAFCHJ_01869 5.81e-43 - - - S ko:K07090 - ko00000 response to heat
PGOAFCHJ_01870 0.0 celA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGOAFCHJ_01872 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGOAFCHJ_01873 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PGOAFCHJ_01874 1.06e-63 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGOAFCHJ_01875 3.04e-293 gtf1 - - M - - - An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PGOAFCHJ_01876 1.34e-237 - - - M - - - A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PGOAFCHJ_01877 4e-201 - - - H - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PGOAFCHJ_01878 3.68e-277 - - - M - - - lipopolysaccharide 3-alpha-galactosyltransferase activity
PGOAFCHJ_01879 0.0 ascB 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGOAFCHJ_01880 6.09e-130 pncA - - Q ko:K16788 - ko00000,ko02000 isochorismatase
PGOAFCHJ_01881 2.12e-180 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PGOAFCHJ_01882 1.02e-300 aspC 2.6.1.2, 2.6.1.66 - E ko:K14260 ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PGOAFCHJ_01883 1.25e-97 XK27_03180 - - T - - - universal stress protein
PGOAFCHJ_01885 2.34e-200 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PGOAFCHJ_01887 7.04e-305 hlyX - - S ko:K03699 - ko00000,ko02042 COG1253 Hemolysins and related proteins containing CBS domains
PGOAFCHJ_01888 1.18e-181 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01890 8.13e-34 - - - - - - - -
PGOAFCHJ_01891 1.83e-305 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
PGOAFCHJ_01892 1.63e-114 nhaP1 - - P ko:K03316 - ko00000 NhaP-type Na H and K H antiporters
PGOAFCHJ_01894 3.52e-124 mraW1 - - J - - - (SAM)-dependent
PGOAFCHJ_01895 1.19e-233 ytqA - - S ko:K07139 - ko00000 radical SAM protein
PGOAFCHJ_01896 2.4e-237 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PGOAFCHJ_01897 1.04e-110 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGOAFCHJ_01898 4.45e-119 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
PGOAFCHJ_01899 1.13e-218 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PGOAFCHJ_01900 1.48e-13 - - - S - - - Protein of unknown function (DUF4059)
PGOAFCHJ_01901 3.11e-166 tcyN 3.6.3.21 - E ko:K02028,ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01902 1.05e-193 yxeN - - P ko:K02029,ko:K16959,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (Permease
PGOAFCHJ_01904 5.46e-195 - - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGOAFCHJ_01906 3.58e-260 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGOAFCHJ_01907 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 formate acetyltransferase'
PGOAFCHJ_01908 1.5e-184 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 carbonic anhydrase
PGOAFCHJ_01909 9.88e-95 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGOAFCHJ_01912 5.73e-214 - - - V - - - COG1680 Beta-lactamase class C and other penicillin binding proteins
PGOAFCHJ_01913 1.22e-175 cppA - - E - - - CppA N-terminal
PGOAFCHJ_01914 2.5e-121 - - - V ko:K07052 - ko00000 CAAX protease self-immunity
PGOAFCHJ_01915 8.98e-193 gla - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PGOAFCHJ_01916 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PGOAFCHJ_01920 5.77e-58 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
PGOAFCHJ_01923 5.64e-173 - - - KT ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PGOAFCHJ_01924 7.25e-287 comD 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 signal transduction protein with a C-terminal ATPase domain
PGOAFCHJ_01929 1.08e-34 - - - S - - - Bacteriocin class II with double-glycine leader peptide
PGOAFCHJ_01930 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01931 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01934 7.77e-120 XK27_09885 - - V - - - Glycopeptide antibiotics resistance protein
PGOAFCHJ_01935 7.84e-286 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PGOAFCHJ_01936 3.75e-114 yutD - - J - - - protein conserved in bacteria
PGOAFCHJ_01937 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PGOAFCHJ_01939 1.86e-302 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PGOAFCHJ_01940 1.99e-236 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGOAFCHJ_01941 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 penicillin-binding protein
PGOAFCHJ_01942 5.32e-60 ftsL - - D - - - cell division protein FtsL
PGOAFCHJ_01943 2.67e-222 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PGOAFCHJ_01944 1.19e-133 - - - - - - - -
PGOAFCHJ_01947 1.31e-79 - - - J - - - Protein of unknown function (DUF805)
PGOAFCHJ_01948 2.72e-111 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
PGOAFCHJ_01949 4.97e-74 - - - S - - - Protein of unknown function (DUF805)
PGOAFCHJ_01950 4.55e-285 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGOAFCHJ_01951 8.27e-181 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGOAFCHJ_01952 0.0 XK27_00765 - - - ko:K01992 - ko00000,ko00002,ko02000 -
PGOAFCHJ_01953 7.12e-170 ecsA_2 - - V ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
PGOAFCHJ_01954 8.56e-162 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PGOAFCHJ_01955 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PGOAFCHJ_01956 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PGOAFCHJ_01957 1.68e-310 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_01958 1.89e-294 dcuS 2.7.13.3 - T ko:K02476,ko:K07701,ko:K07706,ko:K11614 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
PGOAFCHJ_01959 1.98e-14 - - - - - - - -
PGOAFCHJ_01962 8.38e-187 - - - V ko:K21397 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
PGOAFCHJ_01964 0.0 - - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 MreB/Mbl protein
PGOAFCHJ_01965 5.81e-154 - - - S - - - membrane
PGOAFCHJ_01966 5.47e-98 XK27_02470 - - K - - - LytTr DNA-binding domain protein
PGOAFCHJ_01967 0.0 - - - KT - - - response to antibiotic
PGOAFCHJ_01968 9.61e-173 yebC - - M - - - Membrane
PGOAFCHJ_01969 0.0 - - - S - - - hydrolases of the HAD superfamily
PGOAFCHJ_01970 2.03e-228 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PGOAFCHJ_01972 6.78e-42 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PGOAFCHJ_01976 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGOAFCHJ_01977 3.85e-259 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGOAFCHJ_01978 1.45e-78 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PGOAFCHJ_01979 1.05e-248 aroG 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PGOAFCHJ_01980 2.77e-249 aroH 2.5.1.54 - E ko:K01626 ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024 ko00000,ko00001,ko00002,ko01000 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PGOAFCHJ_01981 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGOAFCHJ_01983 1.7e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PGOAFCHJ_01984 2.28e-218 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Fructokinase
PGOAFCHJ_01985 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 pts system
PGOAFCHJ_01986 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PGOAFCHJ_01987 6.8e-223 scrR - - K ko:K03484 - ko00000,ko03000 Transcriptional regulator
PGOAFCHJ_01988 1.09e-95 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGOAFCHJ_01989 7.41e-80 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 protein conserved in bacteria
PGOAFCHJ_01990 1.22e-126 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGOAFCHJ_01991 3.59e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PGOAFCHJ_01992 6.86e-255 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Belongs to the peptidase M24B family
PGOAFCHJ_01994 2.03e-184 - - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 'abc transporter, ATP-binding protein
PGOAFCHJ_01995 5.25e-39 blpT - - - - - - -
PGOAFCHJ_01999 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PGOAFCHJ_02000 2.01e-216 corA - - P ko:K03284 - ko00000,ko02000 COG0598 Mg2 and Co2 transporters
PGOAFCHJ_02001 1.39e-157 XK27_01040 - - S - - - Protein of unknown function (DUF1129)
PGOAFCHJ_02003 4.1e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGOAFCHJ_02004 4.18e-118 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGOAFCHJ_02005 5.39e-62 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PGOAFCHJ_02006 5.71e-53 XK27_05745 - - - - - - -
PGOAFCHJ_02007 1.76e-279 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
PGOAFCHJ_02009 4.73e-12 - - - - - - - -
PGOAFCHJ_02011 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGOAFCHJ_02012 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PGOAFCHJ_02013 2.79e-120 cvpA - - S ko:K03558 - ko00000 toxin biosynthetic process
PGOAFCHJ_02014 1.18e-20 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PGOAFCHJ_02015 1.52e-198 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGOAFCHJ_02016 6.4e-149 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PGOAFCHJ_02017 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PGOAFCHJ_02018 3.82e-61 - - - S - - - branched-chain amino acid
PGOAFCHJ_02019 1.2e-146 XK27_12120 - - E - - - AzlC protein
PGOAFCHJ_02020 7.47e-235 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGOAFCHJ_02021 1.21e-93 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PGOAFCHJ_02022 3.49e-148 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214, inactive homolog of metal-dependent proteases
PGOAFCHJ_02023 1.3e-44 ykzG - - S - - - Belongs to the UPF0356 family
PGOAFCHJ_02024 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGOAFCHJ_02025 4.18e-148 sle1 3.5.1.28 CBM50 M ko:K22409 - ko00000,ko01000 CHAP domain protein
PGOAFCHJ_02026 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PGOAFCHJ_02027 4e-82 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
PGOAFCHJ_02028 4.38e-113 - - - S - - - Fusaric acid resistance protein-like
PGOAFCHJ_02029 3.32e-283 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PGOAFCHJ_02030 1.38e-158 - - - - - - - -
PGOAFCHJ_02031 4.47e-231 gap 1.2.1.12 - C ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
PGOAFCHJ_02032 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGOAFCHJ_02033 4.66e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PGOAFCHJ_02034 4.89e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGOAFCHJ_02035 7.91e-184 purR - - F ko:K09685 - ko00000,ko03000 operon repressor
PGOAFCHJ_02036 4.14e-229 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 3'-5' exoribonuclease yhaM
PGOAFCHJ_02037 2.42e-231 rmuC - - S ko:K09760 - ko00000 RmuC domain protein
PGOAFCHJ_02038 2.16e-150 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PGOAFCHJ_02039 1.15e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PGOAFCHJ_02040 1.25e-207 rsgA 3.1.3.100 - G ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PGOAFCHJ_02042 1.44e-197 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PGOAFCHJ_02043 2.2e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGOAFCHJ_02044 4.54e-183 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, tatd
PGOAFCHJ_02045 2.12e-97 yneT - - S ko:K06929 - ko00000 CoA-binding protein
PGOAFCHJ_02046 3.11e-67 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PGOAFCHJ_02047 1.83e-183 - - - S - - - Macro domain protein
PGOAFCHJ_02048 2.17e-62 isplu5A - - L ko:K07491 - ko00000 COG1943 Transposase and inactivated derivatives
PGOAFCHJ_02049 4.67e-80 yneP - - L ko:K07107 - ko00000,ko01000 thioesterase
PGOAFCHJ_02050 1.61e-70 bta 1.8.1.8 - CO ko:K03671,ko:K03672 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko01000,ko03110 cell redox homeostasis

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)