ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
MHLEJIOM_00001 8.42e-40 - - - - - - - -
MHLEJIOM_00002 8.06e-137 - - - S - - - Protein of unknown function (DUF1211)
MHLEJIOM_00005 1.02e-180 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHLEJIOM_00008 1.87e-191 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
MHLEJIOM_00009 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHLEJIOM_00010 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00011 1.68e-127 - - - K - - - transcriptional regulator
MHLEJIOM_00012 4.35e-197 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
MHLEJIOM_00013 1.65e-63 - - - - - - - -
MHLEJIOM_00016 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
MHLEJIOM_00017 7.99e-158 - - - S ko:K07090 - ko00000 membrane transporter protein
MHLEJIOM_00018 6.97e-133 - - - S - - - Protein of unknown function (DUF1211)
MHLEJIOM_00019 8.19e-212 - - - P - - - CorA-like Mg2+ transporter protein
MHLEJIOM_00020 3.84e-145 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_00022 2.37e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHLEJIOM_00024 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHLEJIOM_00025 6.62e-143 - - - S - - - Membrane
MHLEJIOM_00026 7.16e-132 - - - - - - - -
MHLEJIOM_00027 2.57e-98 - - - - - - - -
MHLEJIOM_00028 1.17e-68 - - - - - - - -
MHLEJIOM_00029 1.08e-156 azlC - - E - - - branched-chain amino acid
MHLEJIOM_00030 4.31e-65 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
MHLEJIOM_00032 6.28e-34 - - - - - - - -
MHLEJIOM_00033 1.07e-183 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHLEJIOM_00034 6.9e-150 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MHLEJIOM_00035 1.82e-161 kdgR - - K - - - FCD domain
MHLEJIOM_00037 1.64e-72 ps105 - - - - - - -
MHLEJIOM_00038 1.33e-41 - - - - - - - -
MHLEJIOM_00040 2.16e-167 - 1.3.8.1, 1.3.8.7 - I ko:K00248,ko:K00249,ko:K18244 ko00071,ko00280,ko00410,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map00650,map01100,map01110,map01120,map01130,map01200,map01212,map03320 ko00000,ko00001,ko00002,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
MHLEJIOM_00041 5.24e-100 fixA - - C ko:K03521 - ko00000 Electron transfer flavoprotein domain
MHLEJIOM_00042 1.06e-99 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein
MHLEJIOM_00043 1.66e-37 - - - K - - - Helix-turn-helix domain
MHLEJIOM_00044 2.02e-71 - - - S - - - pyridoxamine 5-phosphate
MHLEJIOM_00045 9.14e-199 - - - K - - - Transcriptional activator, Rgg GadR MutR family
MHLEJIOM_00046 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
MHLEJIOM_00047 1.88e-307 - - - EGP - - - Major Facilitator
MHLEJIOM_00049 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
MHLEJIOM_00050 2.34e-140 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
MHLEJIOM_00052 3.93e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_00053 3.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHLEJIOM_00054 2.28e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_00055 1.72e-285 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00058 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MHLEJIOM_00059 3.61e-46 copZ - - P - - - Heavy-metal-associated domain
MHLEJIOM_00060 1.47e-131 dpsB - - P - - - Belongs to the Dps family
MHLEJIOM_00061 3.54e-149 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
MHLEJIOM_00062 1.38e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHLEJIOM_00063 1.43e-292 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHLEJIOM_00064 6.7e-135 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
MHLEJIOM_00065 1.8e-176 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
MHLEJIOM_00066 1.14e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHLEJIOM_00067 1.3e-261 - - - - - - - -
MHLEJIOM_00068 0.0 - - - EGP - - - Major Facilitator
MHLEJIOM_00069 3.5e-138 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_00071 4.78e-162 - - - - - - - -
MHLEJIOM_00073 1.82e-178 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHLEJIOM_00074 6.02e-216 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHLEJIOM_00075 3.04e-280 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHLEJIOM_00076 4.4e-116 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHLEJIOM_00077 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHLEJIOM_00078 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHLEJIOM_00079 5.72e-238 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHLEJIOM_00080 6.52e-248 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHLEJIOM_00081 4.71e-81 - - - - - - - -
MHLEJIOM_00082 2.62e-95 - - - L - - - NUDIX domain
MHLEJIOM_00083 7.94e-123 - - - EG - - - EamA-like transporter family
MHLEJIOM_00084 4.57e-123 - - - S - - - Phospholipase A2
MHLEJIOM_00086 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
MHLEJIOM_00087 1.35e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHLEJIOM_00088 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
MHLEJIOM_00089 4.65e-277 - - - - - - - -
MHLEJIOM_00090 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHLEJIOM_00091 2.29e-167 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHLEJIOM_00092 1.42e-153 yleF - - K - - - Helix-turn-helix domain, rpiR family
MHLEJIOM_00093 9.64e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHLEJIOM_00094 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
MHLEJIOM_00095 4.34e-75 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
MHLEJIOM_00096 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
MHLEJIOM_00097 4.9e-206 lysR5 - - K - - - LysR substrate binding domain
MHLEJIOM_00098 1.38e-255 - - - K - - - Helix-turn-helix XRE-family like proteins
MHLEJIOM_00099 1.91e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
MHLEJIOM_00100 2.26e-215 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_00101 1.54e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MHLEJIOM_00102 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
MHLEJIOM_00104 7.12e-127 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
MHLEJIOM_00105 0.0 - - - - - - - -
MHLEJIOM_00106 1.83e-182 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
MHLEJIOM_00107 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
MHLEJIOM_00108 7.78e-52 - - - - - - - -
MHLEJIOM_00109 2.02e-56 - - - S - - - Protein of unknown function (DUF2089)
MHLEJIOM_00110 4.51e-235 yveB - - I - - - PAP2 superfamily
MHLEJIOM_00111 1.52e-265 mccF - - V - - - LD-carboxypeptidase
MHLEJIOM_00112 2.67e-56 - - - - - - - -
MHLEJIOM_00113 2.61e-261 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
MHLEJIOM_00114 1.37e-114 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
MHLEJIOM_00115 6.75e-245 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHLEJIOM_00116 2.01e-58 - - - - - - - -
MHLEJIOM_00117 2.74e-112 - - - K - - - Transcriptional regulator
MHLEJIOM_00118 2.93e-216 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 alcohol dehydrogenase
MHLEJIOM_00119 6.55e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
MHLEJIOM_00120 2.42e-72 - - - S - - - Protein of unknown function (DUF1516)
MHLEJIOM_00121 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
MHLEJIOM_00122 2.42e-61 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
MHLEJIOM_00123 1.75e-229 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHLEJIOM_00124 2.32e-39 - - - - - - - -
MHLEJIOM_00125 2.46e-133 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHLEJIOM_00126 0.0 - - - - - - - -
MHLEJIOM_00128 1.29e-163 - - - S - - - WxL domain surface cell wall-binding
MHLEJIOM_00129 2.04e-171 - - - S - - - WxL domain surface cell wall-binding
MHLEJIOM_00130 2.43e-242 ynjC - - S - - - Cell surface protein
MHLEJIOM_00132 0.0 - - - L - - - Mga helix-turn-helix domain
MHLEJIOM_00133 5.55e-221 - - - S - - - Protein of unknown function (DUF805)
MHLEJIOM_00134 1.1e-76 - - - - - - - -
MHLEJIOM_00135 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHLEJIOM_00136 6.45e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHLEJIOM_00137 1.16e-204 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHLEJIOM_00138 5.47e-178 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
MHLEJIOM_00139 8.52e-60 - - - S - - - Thiamine-binding protein
MHLEJIOM_00140 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
MHLEJIOM_00141 4.77e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_00142 0.0 bmr3 - - EGP - - - Major Facilitator
MHLEJIOM_00144 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHLEJIOM_00145 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHLEJIOM_00146 3.32e-130 - - - - - - - -
MHLEJIOM_00148 1.58e-90 - - - - - - - -
MHLEJIOM_00149 1.15e-113 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_00150 1.81e-54 - - - - - - - -
MHLEJIOM_00151 2.4e-102 - - - S - - - NUDIX domain
MHLEJIOM_00152 8.25e-271 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
MHLEJIOM_00154 2.45e-246 - - - L - - - Reverse transcriptase (RNA-dependent DNA polymerase)
MHLEJIOM_00157 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
MHLEJIOM_00158 7.74e-37 pts4ABC - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHLEJIOM_00159 1.01e-56 yleF - - K - - - Helix-turn-helix domain, rpiR family
MHLEJIOM_00160 6.68e-118 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHLEJIOM_00161 8.88e-96 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
MHLEJIOM_00162 2.44e-279 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHLEJIOM_00163 1.14e-140 - - - S - - - Putative esterase
MHLEJIOM_00164 2.69e-85 - - - G - - - COG0662 Mannose-6-phosphate isomerase
MHLEJIOM_00165 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
MHLEJIOM_00166 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MHLEJIOM_00167 6.18e-150 - - - - - - - -
MHLEJIOM_00168 1.47e-287 - - - S ko:K06872 - ko00000 TPM domain
MHLEJIOM_00169 8.76e-178 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
MHLEJIOM_00170 6.45e-74 ywjH - - S - - - Protein of unknown function (DUF1634)
MHLEJIOM_00171 1.47e-07 - - - - - - - -
MHLEJIOM_00173 5.12e-117 - - - - - - - -
MHLEJIOM_00174 4.85e-65 - - - - - - - -
MHLEJIOM_00175 1.63e-109 - - - C - - - Flavodoxin
MHLEJIOM_00176 5.54e-50 - - - - - - - -
MHLEJIOM_00177 2.82e-36 - - - - - - - -
MHLEJIOM_00178 2.86e-219 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHLEJIOM_00179 2.27e-94 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MHLEJIOM_00180 4.95e-53 - - - S - - - Transglycosylase associated protein
MHLEJIOM_00181 1.16e-112 - - - S - - - Protein conserved in bacteria
MHLEJIOM_00182 4.15e-34 - - - - - - - -
MHLEJIOM_00183 8.12e-90 asp23 - - S - - - Asp23 family, cell envelope-related function
MHLEJIOM_00184 1.97e-92 asp2 - - S - - - Asp23 family, cell envelope-related function
MHLEJIOM_00185 6.26e-146 - - - S - - - Protein of unknown function (DUF969)
MHLEJIOM_00186 1.42e-195 - - - S - - - Protein of unknown function (DUF979)
MHLEJIOM_00187 1.15e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHLEJIOM_00188 6.15e-139 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHLEJIOM_00189 5.48e-164 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
MHLEJIOM_00190 4.01e-87 - - - - - - - -
MHLEJIOM_00191 1.94e-168 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
MHLEJIOM_00192 1.32e-186 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHLEJIOM_00193 1.49e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
MHLEJIOM_00194 1.11e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
MHLEJIOM_00195 3.26e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
MHLEJIOM_00196 9.76e-237 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHLEJIOM_00197 8.29e-168 - - - S - - - Protein of unknown function (DUF1129)
MHLEJIOM_00198 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHLEJIOM_00199 2.39e-155 - - - - - - - -
MHLEJIOM_00200 1.68e-156 vanR - - K - - - response regulator
MHLEJIOM_00201 2.81e-278 hpk31 - - T - - - Histidine kinase
MHLEJIOM_00202 2.75e-303 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
MHLEJIOM_00203 2.92e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHLEJIOM_00204 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHLEJIOM_00205 4.49e-181 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
MHLEJIOM_00206 8.2e-211 yvgN - - C - - - Aldo keto reductase
MHLEJIOM_00207 1.27e-186 gntR - - K - - - rpiR family
MHLEJIOM_00208 2.98e-216 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
MHLEJIOM_00209 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
MHLEJIOM_00210 6.55e-270 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
MHLEJIOM_00211 3.74e-75 - - - - - - - -
MHLEJIOM_00212 5.86e-167 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHLEJIOM_00213 4.91e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHLEJIOM_00214 2.09e-211 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
MHLEJIOM_00215 1.52e-205 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
MHLEJIOM_00216 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
MHLEJIOM_00217 5.92e-241 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHLEJIOM_00218 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHLEJIOM_00219 3.46e-103 - - - T - - - Sh3 type 3 domain protein
MHLEJIOM_00220 6.31e-173 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHLEJIOM_00221 2.32e-188 - - - M - - - Glycosyltransferase like family 2
MHLEJIOM_00222 1.8e-173 - - - S - - - Protein of unknown function (DUF975)
MHLEJIOM_00223 1.27e-53 - - - - - - - -
MHLEJIOM_00224 1.26e-139 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
MHLEJIOM_00225 8.3e-224 draG - - O - - - ADP-ribosylglycohydrolase
MHLEJIOM_00226 0.0 - - - S - - - ABC transporter
MHLEJIOM_00227 1.39e-173 ypaC - - Q - - - Methyltransferase domain
MHLEJIOM_00228 3.02e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHLEJIOM_00229 2.2e-176 - - - S - - - Putative threonine/serine exporter
MHLEJIOM_00230 2.51e-98 - - - S - - - Threonine/Serine exporter, ThrE
MHLEJIOM_00231 9.31e-273 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
MHLEJIOM_00232 1.04e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MHLEJIOM_00233 1.1e-182 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
MHLEJIOM_00234 3.01e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
MHLEJIOM_00235 1.16e-159 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_00236 7.59e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHLEJIOM_00237 2.26e-303 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_00238 3.37e-151 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHLEJIOM_00239 1.01e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHLEJIOM_00240 4.6e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
MHLEJIOM_00241 3.82e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
MHLEJIOM_00242 6.86e-202 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
MHLEJIOM_00245 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
MHLEJIOM_00246 4.55e-206 - - - - - - - -
MHLEJIOM_00247 7.14e-157 - - - - - - - -
MHLEJIOM_00248 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
MHLEJIOM_00249 3.49e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHLEJIOM_00250 9.04e-110 - - - - - - - -
MHLEJIOM_00251 0.0 strH 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Gram-positive signal peptide protein, YSIRK family
MHLEJIOM_00252 3.57e-246 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
MHLEJIOM_00253 5.43e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
MHLEJIOM_00254 9.86e-282 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
MHLEJIOM_00255 2.26e-288 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHLEJIOM_00256 0.0 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
MHLEJIOM_00257 5.61e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_00258 2.74e-27 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_00259 6.51e-166 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_00260 3.66e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_00261 2.72e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHLEJIOM_00262 2.25e-08 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MHLEJIOM_00263 7.18e-226 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
MHLEJIOM_00264 4.34e-242 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHLEJIOM_00265 3.66e-250 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHLEJIOM_00266 1.32e-155 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_00267 6.13e-150 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_00268 2.96e-78 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_00269 2.04e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHLEJIOM_00270 2.01e-240 - - - E - - - M42 glutamyl aminopeptidase
MHLEJIOM_00271 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_00272 2.45e-309 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
MHLEJIOM_00273 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHLEJIOM_00274 1.2e-153 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
MHLEJIOM_00276 1.31e-122 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
MHLEJIOM_00277 5.81e-306 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHLEJIOM_00278 1.09e-141 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MHLEJIOM_00279 9.41e-164 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHLEJIOM_00280 1.25e-107 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
MHLEJIOM_00281 1.75e-193 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHLEJIOM_00282 6.07e-138 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHLEJIOM_00283 4.99e-186 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHLEJIOM_00284 0.0 - - - E - - - Amino acid permease
MHLEJIOM_00285 3.34e-45 - - - - - - - -
MHLEJIOM_00286 2.83e-238 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHLEJIOM_00287 5.41e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHLEJIOM_00288 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHLEJIOM_00289 4.84e-198 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHLEJIOM_00290 1.41e-214 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
MHLEJIOM_00291 1.34e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHLEJIOM_00292 2.97e-54 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
MHLEJIOM_00293 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
MHLEJIOM_00294 1.86e-304 - - - EGP - - - Major Facilitator
MHLEJIOM_00295 2.2e-95 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
MHLEJIOM_00296 7.18e-130 - - - - - - - -
MHLEJIOM_00297 4.22e-41 - - - - - - - -
MHLEJIOM_00298 1.18e-82 - - - S - - - Protein of unknown function (DUF1093)
MHLEJIOM_00299 9.82e-118 - - - - - - - -
MHLEJIOM_00300 3.43e-111 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHLEJIOM_00301 5.73e-155 - - - - - - - -
MHLEJIOM_00302 3.95e-128 - - - - - - - -
MHLEJIOM_00303 9.59e-157 - - - - - - - -
MHLEJIOM_00304 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
MHLEJIOM_00305 4.69e-250 - - - GKT - - - transcriptional antiterminator
MHLEJIOM_00306 3.38e-66 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_00307 5.62e-292 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHLEJIOM_00308 4.14e-89 - - - - - - - -
MHLEJIOM_00309 6.47e-208 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHLEJIOM_00310 1.56e-202 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MHLEJIOM_00311 7.12e-90 - 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Glycerate kinase family
MHLEJIOM_00312 3.85e-279 - 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_00313 1.64e-310 - 3.2.1.24 GH38 G ko:K01191 ko00511,map00511 ko00000,ko00001,ko01000,ko04131 Alpha mannosidase, middle domain
MHLEJIOM_00314 6.55e-227 - - - G - - - mannose-6-phosphate isomerase
MHLEJIOM_00315 2.16e-203 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
MHLEJIOM_00316 1.05e-127 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
MHLEJIOM_00317 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00318 1.62e-191 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
MHLEJIOM_00319 1.43e-26 - - - K - - - helix_turn_helix, arabinose operon control protein
MHLEJIOM_00320 0.0 - - - K - - - Sigma-54 interaction domain
MHLEJIOM_00321 6.79e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHLEJIOM_00322 2.66e-117 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_00323 5.53e-196 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_00324 2.15e-199 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_00325 9.35e-74 - - - - - - - -
MHLEJIOM_00326 0.0 - 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
MHLEJIOM_00328 2.2e-222 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
MHLEJIOM_00329 3.74e-204 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
MHLEJIOM_00330 4.94e-214 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHLEJIOM_00331 4.26e-253 - - - EGP - - - Major Facilitator Superfamily
MHLEJIOM_00332 2.16e-207 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHLEJIOM_00333 1.26e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHLEJIOM_00334 4.66e-206 - - - G - - - Xylose isomerase-like TIM barrel
MHLEJIOM_00335 1.93e-210 - - - K - - - Transcriptional regulator, LysR family
MHLEJIOM_00336 1.66e-117 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
MHLEJIOM_00337 0.0 ycaM - - E - - - amino acid
MHLEJIOM_00338 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
MHLEJIOM_00339 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHLEJIOM_00340 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHLEJIOM_00341 1.97e-118 - - - - - - - -
MHLEJIOM_00342 7.61e-269 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHLEJIOM_00343 4.81e-181 - - - V - - - ATPases associated with a variety of cellular activities
MHLEJIOM_00344 5.11e-253 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHLEJIOM_00345 4.61e-156 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
MHLEJIOM_00346 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
MHLEJIOM_00347 3.92e-163 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_00348 2.6e-257 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHLEJIOM_00349 1.25e-236 - - - M - - - LPXTG cell wall anchor motif
MHLEJIOM_00350 4.79e-161 - - - M - - - domain protein
MHLEJIOM_00351 0.0 yvcC - - M - - - Cna protein B-type domain
MHLEJIOM_00352 7.58e-134 tnpR1 - - L - - - Resolvase, N terminal domain
MHLEJIOM_00353 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHLEJIOM_00354 2.08e-205 - - - S - - - reductase
MHLEJIOM_00355 9.74e-98 - - - K - - - helix_turn_helix, mercury resistance
MHLEJIOM_00356 0.0 - - - E - - - Amino acid permease
MHLEJIOM_00357 3.99e-281 - - - S ko:K07045 - ko00000 Amidohydrolase
MHLEJIOM_00358 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
MHLEJIOM_00359 6.65e-183 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
MHLEJIOM_00360 1.51e-183 - - - H - - - Protein of unknown function (DUF1698)
MHLEJIOM_00361 1.09e-190 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHLEJIOM_00362 3.36e-247 pbpE - - V - - - Beta-lactamase
MHLEJIOM_00363 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHLEJIOM_00364 5.36e-215 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
MHLEJIOM_00365 2.28e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHLEJIOM_00366 8.11e-138 ydfF - - K - - - Transcriptional
MHLEJIOM_00367 2.48e-256 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
MHLEJIOM_00368 3.49e-63 yczG - - K - - - Helix-turn-helix domain
MHLEJIOM_00369 0.0 - - - L - - - Exonuclease
MHLEJIOM_00370 1.01e-99 - - - O - - - OsmC-like protein
MHLEJIOM_00371 1.71e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
MHLEJIOM_00372 4.95e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
MHLEJIOM_00373 2.1e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
MHLEJIOM_00374 1.43e-130 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_00375 4.2e-22 - - - - - - - -
MHLEJIOM_00376 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
MHLEJIOM_00377 4.99e-105 - - - - - - - -
MHLEJIOM_00378 5.84e-253 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
MHLEJIOM_00379 1.76e-197 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHLEJIOM_00380 0.0 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
MHLEJIOM_00381 4.56e-242 - - - G - - - Major Facilitator Superfamily
MHLEJIOM_00382 0.0 - - - GK - - - helix_turn_helix, arabinose operon control protein
MHLEJIOM_00383 0.0 pip - - V ko:K01421 - ko00000 domain protein
MHLEJIOM_00385 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MHLEJIOM_00386 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHLEJIOM_00387 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHLEJIOM_00388 8.75e-90 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHLEJIOM_00389 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MHLEJIOM_00390 7.9e-196 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_00391 2.18e-177 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_00392 1.48e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_00393 1.15e-237 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHLEJIOM_00394 1.49e-58 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
MHLEJIOM_00395 7.51e-194 - - - S - - - hydrolase
MHLEJIOM_00396 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
MHLEJIOM_00397 5.82e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00398 6.63e-237 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHLEJIOM_00399 1.26e-112 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_00400 5.28e-181 - - - M - - - hydrolase, family 25
MHLEJIOM_00401 1.33e-17 - - - S - - - YvrJ protein family
MHLEJIOM_00403 4.55e-304 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
MHLEJIOM_00404 4.25e-150 - - - P ko:K16958 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_00405 1.74e-146 ytmL - - P ko:K16958,ko:K16959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_00406 1.11e-202 - - - ET ko:K16957 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial periplasmic substrate-binding proteins
MHLEJIOM_00407 1.43e-172 yxeO - - E ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
MHLEJIOM_00408 9.57e-244 - 1.5.1.28 - C ko:K04940 - ko00000,ko01000 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MHLEJIOM_00409 5.06e-280 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MHLEJIOM_00410 0.0 - 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_00411 2.35e-125 - 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
MHLEJIOM_00412 5.04e-147 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
MHLEJIOM_00413 2.38e-173 - - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MHLEJIOM_00414 6.14e-155 - - - S - - - Haloacid dehalogenase-like hydrolase
MHLEJIOM_00415 1.4e-172 - - - - - - - -
MHLEJIOM_00420 9.15e-285 int3 - - L - - - Belongs to the 'phage' integrase family
MHLEJIOM_00422 6e-24 - - - - - - - -
MHLEJIOM_00423 0.0 - - - L - - - Protein of unknown function (DUF3991)
MHLEJIOM_00425 2.02e-287 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
MHLEJIOM_00427 0.000235 - - - S - - - Ribbon-helix-helix protein, copG family
MHLEJIOM_00432 4e-234 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 cysteine-type peptidase activity
MHLEJIOM_00433 0.0 - - - S - - - COG0433 Predicted ATPase
MHLEJIOM_00434 3.2e-137 - - - - - - - -
MHLEJIOM_00436 0.0 - - - S - - - domain, Protein
MHLEJIOM_00437 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MHLEJIOM_00438 4.96e-123 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
MHLEJIOM_00441 3.84e-300 - - - M - - - Domain of unknown function (DUF5011)
MHLEJIOM_00442 1.74e-260 - - - - - - - -
MHLEJIOM_00443 6.78e-42 - - - - - - - -
MHLEJIOM_00447 6.53e-199 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
MHLEJIOM_00448 1e-214 - - - L ko:K07497 - ko00000 hmm pf00665
MHLEJIOM_00449 2.05e-173 - - - L - - - Helix-turn-helix domain
MHLEJIOM_00450 2.11e-69 - - - L ko:K07483 - ko00000 4.5 Transposon and IS
MHLEJIOM_00451 8.29e-74 - - - - - - - -
MHLEJIOM_00452 4.73e-205 - - - - - - - -
MHLEJIOM_00453 0.000324 - - - S - - - CsbD-like
MHLEJIOM_00454 9.52e-240 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MHLEJIOM_00455 4.76e-105 - - - - - - - -
MHLEJIOM_00457 1.75e-171 - - - - - - - -
MHLEJIOM_00458 1.56e-93 - - - - - - - -
MHLEJIOM_00460 2.94e-198 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
MHLEJIOM_00461 9.06e-180 - - - L - - - Helix-turn-helix domain
MHLEJIOM_00467 1.66e-59 - - - S - - - Domain of unknown function (DUF1883)
MHLEJIOM_00468 2.14e-177 - - - S - - - ORF6N domain
MHLEJIOM_00469 4.03e-202 ps305 - - S - - - Protein of unknown function (Hypoth_ymh)
MHLEJIOM_00472 1.51e-80 - - - K - - - Helix-turn-helix XRE-family like proteins
MHLEJIOM_00473 2.33e-25 - - - E - - - Zn peptidase
MHLEJIOM_00474 2.11e-256 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHLEJIOM_00475 4.27e-309 xylP - - G - - - MFS/sugar transport protein
MHLEJIOM_00476 2.42e-163 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MHLEJIOM_00477 1.28e-145 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00478 9.14e-26 - - - S - - - Adenine-specific methyltransferase EcoRI
MHLEJIOM_00479 5.47e-76 - - - S - - - Protein of unknown function (DUF1722)
MHLEJIOM_00480 6.62e-66 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
MHLEJIOM_00481 4.96e-44 - - - L - - - RelB antitoxin
MHLEJIOM_00482 2.11e-271 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
MHLEJIOM_00483 6.84e-186 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
MHLEJIOM_00484 5.79e-157 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_00485 1.25e-45 - - - - - - - -
MHLEJIOM_00486 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
MHLEJIOM_00487 3.65e-90 - - - S - - - WxL domain surface cell wall-binding
MHLEJIOM_00488 4.06e-224 - - - S - - - Cell surface protein
MHLEJIOM_00489 5.11e-58 - - - - - - - -
MHLEJIOM_00490 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHLEJIOM_00491 1.37e-153 - - - S - - - WxL domain surface cell wall-binding
MHLEJIOM_00492 4.46e-74 - - - - - - - -
MHLEJIOM_00493 1.73e-138 - - - N - - - WxL domain surface cell wall-binding
MHLEJIOM_00495 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
MHLEJIOM_00496 6.94e-225 yicL - - EG - - - EamA-like transporter family
MHLEJIOM_00497 0.0 - - - - - - - -
MHLEJIOM_00498 3.03e-186 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_00499 4.07e-114 - - - S - - - ECF-type riboflavin transporter, S component
MHLEJIOM_00500 3.54e-190 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
MHLEJIOM_00501 7.88e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
MHLEJIOM_00502 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHLEJIOM_00503 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00504 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_00505 3.34e-286 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
MHLEJIOM_00506 1.56e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
MHLEJIOM_00507 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHLEJIOM_00508 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHLEJIOM_00509 1.51e-283 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MHLEJIOM_00510 0.0 - - - E ko:K03294 - ko00000 Amino Acid
MHLEJIOM_00511 3.08e-189 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
MHLEJIOM_00512 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
MHLEJIOM_00513 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
MHLEJIOM_00514 2.98e-89 - - - - - - - -
MHLEJIOM_00515 1.37e-99 - - - O - - - OsmC-like protein
MHLEJIOM_00516 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
MHLEJIOM_00517 4.53e-146 ylbE - - GM - - - NAD(P)H-binding
MHLEJIOM_00518 3.18e-201 - - - S - - - Aldo/keto reductase family
MHLEJIOM_00519 9.04e-317 yifK - - E ko:K03293 - ko00000 Amino acid permease
MHLEJIOM_00520 0.0 - - - S - - - Protein of unknown function (DUF3800)
MHLEJIOM_00521 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
MHLEJIOM_00522 5.49e-78 - - - S - - - Protein of unknown function (DUF3021)
MHLEJIOM_00523 1.2e-95 - - - K - - - LytTr DNA-binding domain
MHLEJIOM_00524 2.19e-191 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
MHLEJIOM_00525 2.25e-209 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_00526 5.05e-187 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHLEJIOM_00527 1.06e-156 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
MHLEJIOM_00528 1.06e-69 ybjQ - - S - - - Belongs to the UPF0145 family
MHLEJIOM_00529 3.97e-201 - - - C - - - nadph quinone reductase
MHLEJIOM_00530 3.8e-316 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
MHLEJIOM_00531 5.64e-227 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
MHLEJIOM_00532 2.22e-154 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
MHLEJIOM_00533 6.17e-55 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
MHLEJIOM_00534 1.03e-22 - - - M - - - Peptidoglycan-binding domain 1 protein
MHLEJIOM_00538 2.24e-32 - - - - - - - -
MHLEJIOM_00540 8.43e-17 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MHLEJIOM_00543 2.48e-64 - - - M - - - Glycosyltransferase like family 2
MHLEJIOM_00544 7.26e-208 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
MHLEJIOM_00545 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
MHLEJIOM_00546 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHLEJIOM_00547 2.65e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHLEJIOM_00548 0.000238 aarA 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
MHLEJIOM_00549 1.09e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 proteolysis
MHLEJIOM_00550 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
MHLEJIOM_00551 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
MHLEJIOM_00552 1.8e-145 ung2 - - L - - - Uracil-DNA glycosylase
MHLEJIOM_00553 3.16e-169 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
MHLEJIOM_00554 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
MHLEJIOM_00555 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHLEJIOM_00556 7.27e-173 - - - M - - - Glycosyltransferase like family 2
MHLEJIOM_00557 1.35e-281 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHLEJIOM_00558 1.42e-245 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
MHLEJIOM_00559 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
MHLEJIOM_00560 1.19e-218 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
MHLEJIOM_00561 4.99e-253 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
MHLEJIOM_00564 3.35e-111 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_00565 2.68e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_00566 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHLEJIOM_00567 9.83e-37 - - - - - - - -
MHLEJIOM_00568 1.29e-159 - - - S - - - Domain of unknown function (DUF4867)
MHLEJIOM_00569 5e-225 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MHLEJIOM_00570 4.89e-238 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
MHLEJIOM_00571 4.53e-122 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
MHLEJIOM_00572 1.25e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
MHLEJIOM_00573 4.13e-181 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
MHLEJIOM_00574 3.73e-150 - - - S - - - HAD hydrolase, family IA, variant
MHLEJIOM_00575 4.59e-270 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHLEJIOM_00576 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
MHLEJIOM_00577 6.8e-21 - - - - - - - -
MHLEJIOM_00578 7.42e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHLEJIOM_00580 3.78e-271 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
MHLEJIOM_00581 7.48e-190 - - - I - - - alpha/beta hydrolase fold
MHLEJIOM_00582 6.13e-156 yrkL - - S - - - Flavodoxin-like fold
MHLEJIOM_00584 7.44e-113 - - - S - - - Short repeat of unknown function (DUF308)
MHLEJIOM_00585 1.92e-153 - - - S - - - Psort location Cytoplasmic, score
MHLEJIOM_00586 9.5e-199 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
MHLEJIOM_00587 1.12e-250 - - - - - - - -
MHLEJIOM_00589 3.99e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MHLEJIOM_00590 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
MHLEJIOM_00591 3.73e-214 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
MHLEJIOM_00592 3.99e-211 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_00593 2.78e-207 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHLEJIOM_00594 3.37e-180 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00595 6.79e-222 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
MHLEJIOM_00596 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
MHLEJIOM_00597 8.07e-233 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
MHLEJIOM_00598 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
MHLEJIOM_00599 8.84e-93 - - - S - - - GtrA-like protein
MHLEJIOM_00600 3.91e-159 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
MHLEJIOM_00601 3.66e-310 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
MHLEJIOM_00602 2.42e-88 - - - S - - - Belongs to the HesB IscA family
MHLEJIOM_00603 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
MHLEJIOM_00604 1.12e-208 - - - S - - - KR domain
MHLEJIOM_00605 5.05e-70 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MHLEJIOM_00606 1.3e-117 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
MHLEJIOM_00607 1.4e-155 ydgI - - C - - - Nitroreductase family
MHLEJIOM_00608 1.84e-262 lldD 1.13.12.4 - C ko:K00467 ko00620,map00620 ko00000,ko00001,ko01000 IMP dehydrogenase / GMP reductase domain
MHLEJIOM_00611 8.53e-227 - - - K - - - DNA-binding helix-turn-helix protein
MHLEJIOM_00612 1.17e-77 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHLEJIOM_00613 2.7e-62 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
MHLEJIOM_00614 4.91e-55 - - - - - - - -
MHLEJIOM_00615 1.17e-244 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHLEJIOM_00617 3.79e-71 - - - - - - - -
MHLEJIOM_00618 1.79e-104 - - - - - - - -
MHLEJIOM_00619 5.77e-267 XK27_05220 - - S - - - AI-2E family transporter
MHLEJIOM_00620 1.58e-33 - - - - - - - -
MHLEJIOM_00621 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHLEJIOM_00622 3.6e-59 - - - - - - - -
MHLEJIOM_00623 8.47e-214 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
MHLEJIOM_00624 8.37e-116 - - - S - - - Flavin reductase like domain
MHLEJIOM_00625 9.67e-91 - - - - - - - -
MHLEJIOM_00626 5.39e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHLEJIOM_00627 1.7e-81 yeaO - - S - - - Protein of unknown function, DUF488
MHLEJIOM_00628 7.36e-222 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHLEJIOM_00629 1.14e-199 mleR - - K - - - LysR family
MHLEJIOM_00630 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
MHLEJIOM_00631 3.58e-217 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
MHLEJIOM_00632 8.23e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHLEJIOM_00633 4.6e-113 - - - C - - - FMN binding
MHLEJIOM_00634 0.0 pepF - - E - - - Oligopeptidase F
MHLEJIOM_00635 1.11e-77 - - - - - - - -
MHLEJIOM_00636 3.81e-170 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHLEJIOM_00637 4.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
MHLEJIOM_00638 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
MHLEJIOM_00639 1.56e-230 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 carboxylic ester hydrolase activity
MHLEJIOM_00640 1.69e-58 - - - - - - - -
MHLEJIOM_00641 4.89e-122 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHLEJIOM_00642 1.14e-255 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHLEJIOM_00643 7.46e-157 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
MHLEJIOM_00644 2.24e-101 - - - K - - - Transcriptional regulator
MHLEJIOM_00645 2.4e-231 ybcH - - D ko:K06889 - ko00000 Alpha beta
MHLEJIOM_00646 3.83e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
MHLEJIOM_00647 2.52e-199 dkgB - - S - - - reductase
MHLEJIOM_00648 2.75e-200 - - - - - - - -
MHLEJIOM_00649 1.02e-197 - - - S - - - Alpha beta hydrolase
MHLEJIOM_00650 7.76e-152 yviA - - S - - - Protein of unknown function (DUF421)
MHLEJIOM_00651 4.49e-97 - - - S - - - Protein of unknown function (DUF3290)
MHLEJIOM_00652 5.92e-284 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
MHLEJIOM_00653 1.69e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHLEJIOM_00654 1.3e-136 yjbF - - S - - - SNARE associated Golgi protein
MHLEJIOM_00655 2.95e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHLEJIOM_00656 4.54e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHLEJIOM_00657 7.52e-263 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHLEJIOM_00658 1.41e-288 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHLEJIOM_00659 1.83e-87 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHLEJIOM_00660 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
MHLEJIOM_00661 2.06e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
MHLEJIOM_00662 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHLEJIOM_00663 3.59e-264 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHLEJIOM_00664 1.13e-307 ytoI - - K - - - DRTGG domain
MHLEJIOM_00665 3.03e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MHLEJIOM_00666 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHLEJIOM_00667 7.36e-222 - - - - - - - -
MHLEJIOM_00668 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHLEJIOM_00670 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
MHLEJIOM_00671 2.67e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHLEJIOM_00672 1.3e-69 yrzB - - S - - - Belongs to the UPF0473 family
MHLEJIOM_00673 1.65e-47 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHLEJIOM_00674 1.89e-119 cvpA - - S - - - Colicin V production protein
MHLEJIOM_00675 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHLEJIOM_00676 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
MHLEJIOM_00677 1.04e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
MHLEJIOM_00678 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHLEJIOM_00679 9.86e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
MHLEJIOM_00680 6.97e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHLEJIOM_00681 9.67e-311 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHLEJIOM_00682 4.76e-111 yslB - - S - - - Protein of unknown function (DUF2507)
MHLEJIOM_00683 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
MHLEJIOM_00684 1.91e-124 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
MHLEJIOM_00685 1.9e-175 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
MHLEJIOM_00686 9.32e-112 ykuL - - S - - - CBS domain
MHLEJIOM_00687 1.62e-199 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
MHLEJIOM_00688 6.86e-198 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
MHLEJIOM_00689 1.49e-46 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHLEJIOM_00690 4.84e-114 ytxH - - S - - - YtxH-like protein
MHLEJIOM_00691 6.15e-116 yrxA - - S ko:K07105 - ko00000 3H domain
MHLEJIOM_00692 1.8e-273 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHLEJIOM_00693 3.03e-232 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
MHLEJIOM_00694 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
MHLEJIOM_00695 6.14e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
MHLEJIOM_00696 6.86e-176 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHLEJIOM_00697 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
MHLEJIOM_00698 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
MHLEJIOM_00699 9.98e-73 - - - - - - - -
MHLEJIOM_00700 1.2e-240 yibE - - S - - - overlaps another CDS with the same product name
MHLEJIOM_00701 3.27e-151 yibF - - S - - - overlaps another CDS with the same product name
MHLEJIOM_00702 3.02e-147 - - - S - - - Calcineurin-like phosphoesterase
MHLEJIOM_00703 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
MHLEJIOM_00704 1.02e-150 yutD - - S - - - Protein of unknown function (DUF1027)
MHLEJIOM_00705 1.34e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHLEJIOM_00706 2.62e-145 - - - S - - - Protein of unknown function (DUF1461)
MHLEJIOM_00707 8.69e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
MHLEJIOM_00708 2.26e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
MHLEJIOM_00709 1.35e-237 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
MHLEJIOM_00710 2.99e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHLEJIOM_00711 1.17e-82 yugI - - J ko:K07570 - ko00000 general stress protein
MHLEJIOM_00727 4.8e-122 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
MHLEJIOM_00728 0.0 ybeC - - E - - - amino acid
MHLEJIOM_00729 2.2e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHLEJIOM_00730 3.8e-251 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
MHLEJIOM_00731 1.58e-220 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHLEJIOM_00733 1.98e-280 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHLEJIOM_00734 1.52e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
MHLEJIOM_00735 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHLEJIOM_00736 8.92e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
MHLEJIOM_00739 1.32e-89 - - - - - - - -
MHLEJIOM_00740 7.89e-268 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHLEJIOM_00741 0.0 mdr - - EGP - - - Major Facilitator
MHLEJIOM_00742 1.62e-94 - - - K - - - MerR HTH family regulatory protein
MHLEJIOM_00743 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MHLEJIOM_00744 8.79e-154 - - - S - - - Domain of unknown function (DUF4811)
MHLEJIOM_00745 7.4e-155 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
MHLEJIOM_00746 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
MHLEJIOM_00747 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHLEJIOM_00748 9.39e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHLEJIOM_00749 1.58e-45 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MHLEJIOM_00750 2.76e-182 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHLEJIOM_00751 8.88e-122 - - - F - - - NUDIX domain
MHLEJIOM_00753 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHLEJIOM_00754 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
MHLEJIOM_00755 2.8e-111 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
MHLEJIOM_00758 9.02e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
MHLEJIOM_00759 0.0 cpdA - - S - - - Calcineurin-like phosphoesterase
MHLEJIOM_00760 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
MHLEJIOM_00761 3.93e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
MHLEJIOM_00762 2.85e-271 coiA - - S ko:K06198 - ko00000 Competence protein
MHLEJIOM_00763 6.41e-148 yjbH - - Q - - - Thioredoxin
MHLEJIOM_00764 7.28e-138 - - - S - - - CYTH
MHLEJIOM_00765 1.19e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
MHLEJIOM_00766 6.06e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHLEJIOM_00767 2.88e-218 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHLEJIOM_00768 9.8e-259 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHLEJIOM_00769 4.16e-144 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
MHLEJIOM_00770 1.09e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHLEJIOM_00771 9.35e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
MHLEJIOM_00772 2e-82 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHLEJIOM_00773 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHLEJIOM_00774 4.94e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHLEJIOM_00775 1.12e-218 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
MHLEJIOM_00776 3.44e-200 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
MHLEJIOM_00777 3.08e-123 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHLEJIOM_00778 4.04e-94 - - - S - - - Protein of unknown function (DUF1149)
MHLEJIOM_00779 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHLEJIOM_00780 1.1e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
MHLEJIOM_00781 1.32e-307 ymfH - - S - - - Peptidase M16
MHLEJIOM_00782 1.22e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHLEJIOM_00783 1.15e-169 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
MHLEJIOM_00784 9.93e-136 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHLEJIOM_00785 1.05e-293 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
MHLEJIOM_00786 5.55e-245 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHLEJIOM_00787 7.95e-317 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
MHLEJIOM_00788 2.93e-151 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
MHLEJIOM_00789 1.11e-299 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
MHLEJIOM_00790 1.06e-104 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
MHLEJIOM_00791 3.24e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHLEJIOM_00792 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHLEJIOM_00793 2.49e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHLEJIOM_00794 1.28e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
MHLEJIOM_00796 2.23e-258 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
MHLEJIOM_00797 2.49e-166 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHLEJIOM_00798 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHLEJIOM_00799 1.76e-196 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHLEJIOM_00800 4.48e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
MHLEJIOM_00801 1.06e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
MHLEJIOM_00802 9.06e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHLEJIOM_00803 3.54e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHLEJIOM_00804 3.82e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
MHLEJIOM_00805 0.0 yvlB - - S - - - Putative adhesin
MHLEJIOM_00806 5.23e-50 - - - - - - - -
MHLEJIOM_00807 3.07e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
MHLEJIOM_00808 8.27e-223 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHLEJIOM_00809 7.94e-202 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHLEJIOM_00810 6.29e-250 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
MHLEJIOM_00811 1.43e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHLEJIOM_00812 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MHLEJIOM_00813 5.88e-146 - - - T - - - Transcriptional regulatory protein, C terminal
MHLEJIOM_00814 1.38e-223 - - - T - - - His Kinase A (phosphoacceptor) domain
MHLEJIOM_00815 8.5e-118 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_00816 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHLEJIOM_00817 1.99e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
MHLEJIOM_00818 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHLEJIOM_00819 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHLEJIOM_00820 2.56e-111 - - - S - - - Short repeat of unknown function (DUF308)
MHLEJIOM_00821 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
MHLEJIOM_00822 2.99e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
MHLEJIOM_00823 9.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
MHLEJIOM_00824 3.19e-105 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
MHLEJIOM_00825 5.97e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHLEJIOM_00827 1.22e-28 - - - M - - - Host cell surface-exposed lipoprotein
MHLEJIOM_00828 5.52e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
MHLEJIOM_00829 2.1e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHLEJIOM_00830 2.16e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
MHLEJIOM_00831 2.81e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHLEJIOM_00832 3.4e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHLEJIOM_00833 4.28e-292 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MHLEJIOM_00834 5.21e-61 - - - - - - - -
MHLEJIOM_00835 0.0 eriC - - P ko:K03281 - ko00000 chloride
MHLEJIOM_00836 5.04e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
MHLEJIOM_00837 4.01e-181 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
MHLEJIOM_00838 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHLEJIOM_00839 4.47e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHLEJIOM_00840 1.89e-227 yvdE - - K - - - helix_turn _helix lactose operon repressor
MHLEJIOM_00841 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MHLEJIOM_00842 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHLEJIOM_00843 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHLEJIOM_00844 8.22e-154 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHLEJIOM_00845 5.02e-20 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_00846 1.55e-21 - - - - - - - -
MHLEJIOM_00847 1.13e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MHLEJIOM_00848 7.26e-306 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
MHLEJIOM_00849 2.9e-310 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHLEJIOM_00850 1.1e-188 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_00851 7.01e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
MHLEJIOM_00852 3.08e-248 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_00853 2.1e-135 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
MHLEJIOM_00854 7.57e-119 - - - - - - - -
MHLEJIOM_00855 4e-203 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHLEJIOM_00856 8.4e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHLEJIOM_00857 1.75e-227 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
MHLEJIOM_00858 9.11e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
MHLEJIOM_00860 1.71e-209 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_00861 2.34e-271 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_00862 8.04e-129 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHLEJIOM_00863 4.71e-193 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
MHLEJIOM_00864 4.74e-213 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
MHLEJIOM_00865 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
MHLEJIOM_00866 1.97e-124 - - - K - - - Cupin domain
MHLEJIOM_00867 9.1e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHLEJIOM_00868 2.91e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_00869 2.88e-187 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_00870 8.49e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_00872 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
MHLEJIOM_00873 1.82e-144 - - - K - - - Transcriptional regulator
MHLEJIOM_00875 3.66e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHLEJIOM_00876 3.82e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHLEJIOM_00877 1.41e-217 ybbR - - S - - - YbbR-like protein
MHLEJIOM_00878 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHLEJIOM_00879 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHLEJIOM_00880 0.0 pepF2 - - E - - - Oligopeptidase F
MHLEJIOM_00881 3.35e-106 - - - S - - - VanZ like family
MHLEJIOM_00882 5.85e-169 yebC - - K - - - Transcriptional regulatory protein
MHLEJIOM_00883 4.13e-196 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
MHLEJIOM_00884 3.22e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
MHLEJIOM_00885 8.6e-37 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
MHLEJIOM_00887 3.85e-31 - - - - - - - -
MHLEJIOM_00888 1.42e-24 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
MHLEJIOM_00890 7.21e-237 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
MHLEJIOM_00891 2.1e-81 - - - - - - - -
MHLEJIOM_00892 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
MHLEJIOM_00893 6.17e-190 arbV - - I - - - Phosphate acyltransferases
MHLEJIOM_00894 8.22e-212 arbx - - M - - - Glycosyl transferase family 8
MHLEJIOM_00895 1.63e-233 arbY - - M - - - family 8
MHLEJIOM_00896 2.18e-212 arbZ - - I - - - Phosphate acyltransferases
MHLEJIOM_00897 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHLEJIOM_00899 2.04e-273 sip - - L - - - Belongs to the 'phage' integrase family
MHLEJIOM_00900 8.04e-80 - - - - - - - -
MHLEJIOM_00901 1.93e-19 - - - - - - - -
MHLEJIOM_00902 6.23e-35 - - - - - - - -
MHLEJIOM_00903 8.63e-45 - - - - - - - -
MHLEJIOM_00904 1.78e-11 - - - - - - - -
MHLEJIOM_00905 8.14e-201 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
MHLEJIOM_00906 0.0 - - - S - - - Virulence-associated protein E
MHLEJIOM_00907 2.06e-98 - - - - - - - -
MHLEJIOM_00908 6.36e-103 terS - - L - - - Phage terminase, small subunit
MHLEJIOM_00909 0.0 terL - - S - - - overlaps another CDS with the same product name
MHLEJIOM_00910 6.27e-31 - - - - - - - -
MHLEJIOM_00911 4.85e-278 - - - S - - - Phage portal protein
MHLEJIOM_00912 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
MHLEJIOM_00913 6.54e-63 - - - S - - - Phage gp6-like head-tail connector protein
MHLEJIOM_00914 6.83e-18 - - - S - - - Phage head-tail joining protein
MHLEJIOM_00915 2.3e-23 - - - - - - - -
MHLEJIOM_00916 1.4e-35 ytgB - - S - - - Transglycosylase associated protein
MHLEJIOM_00918 6.55e-93 - - - S - - - SdpI/YhfL protein family
MHLEJIOM_00919 3.55e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
MHLEJIOM_00920 0.0 yclK - - T - - - Histidine kinase
MHLEJIOM_00921 3.29e-97 - - - S - - - acetyltransferase
MHLEJIOM_00922 7.39e-20 - - - - - - - -
MHLEJIOM_00923 7.36e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
MHLEJIOM_00924 1.53e-88 - - - - - - - -
MHLEJIOM_00925 8.56e-74 - - - - - - - -
MHLEJIOM_00926 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MHLEJIOM_00928 1.78e-266 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHLEJIOM_00929 1.43e-179 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
MHLEJIOM_00930 5.65e-46 - - - S - - - Bacterial protein of unknown function (DUF898)
MHLEJIOM_00932 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
MHLEJIOM_00933 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHLEJIOM_00934 4.26e-271 camS - - S - - - sex pheromone
MHLEJIOM_00935 3.61e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHLEJIOM_00936 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHLEJIOM_00937 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHLEJIOM_00938 4.97e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
MHLEJIOM_00939 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHLEJIOM_00940 2.65e-280 yttB - - EGP - - - Major Facilitator
MHLEJIOM_00941 8.81e-191 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHLEJIOM_00942 1.21e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
MHLEJIOM_00943 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MHLEJIOM_00944 0.0 - - - EGP - - - Major Facilitator
MHLEJIOM_00945 4.37e-107 - - - K - - - Acetyltransferase (GNAT) family
MHLEJIOM_00946 2.87e-213 yitS - - S - - - Uncharacterised protein, DegV family COG1307
MHLEJIOM_00947 3.38e-166 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
MHLEJIOM_00948 1.24e-39 - - - - - - - -
MHLEJIOM_00949 2.51e-180 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
MHLEJIOM_00950 9.39e-80 - - - S - - - Protein of unknown function (DUF1093)
MHLEJIOM_00951 1.9e-79 - - - S - - - Domain of unknown function (DUF4828)
MHLEJIOM_00952 1.55e-226 mocA - - S - - - Oxidoreductase
MHLEJIOM_00953 1.16e-300 yfmL - - L - - - DEAD DEAH box helicase
MHLEJIOM_00954 7.9e-74 chbA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
MHLEJIOM_00955 4.49e-93 - - - S - - - Domain of unknown function (DUF3284)
MHLEJIOM_00957 1.04e-06 - - - - - - - -
MHLEJIOM_00958 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHLEJIOM_00959 4.05e-306 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
MHLEJIOM_00960 2.96e-144 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_00962 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
MHLEJIOM_00963 9.73e-230 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
MHLEJIOM_00964 1.24e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
MHLEJIOM_00965 1.16e-204 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
MHLEJIOM_00966 5.25e-259 - - - M - - - Glycosyltransferase like family 2
MHLEJIOM_00968 1.02e-20 - - - - - - - -
MHLEJIOM_00969 4.45e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
MHLEJIOM_00970 4.58e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
MHLEJIOM_00973 4.66e-35 - - - M - - - transferase activity, transferring glycosyl groups
MHLEJIOM_00974 2.27e-37 - - - M - - - transferase activity, transferring glycosyl groups
MHLEJIOM_00976 3.3e-310 secA2 - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHLEJIOM_00977 1.23e-191 licT2 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHLEJIOM_00978 0.0 - - - S - - - Bacterial membrane protein YfhO
MHLEJIOM_00979 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
MHLEJIOM_00980 1.36e-216 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
MHLEJIOM_00981 7.34e-134 - - - - - - - -
MHLEJIOM_00982 8.49e-217 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
MHLEJIOM_00983 6.22e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MHLEJIOM_00984 3.95e-108 yvbK - - K - - - GNAT family
MHLEJIOM_00985 1.45e-149 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
MHLEJIOM_00986 5.35e-133 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHLEJIOM_00987 2.54e-302 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
MHLEJIOM_00988 2.71e-260 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHLEJIOM_00989 1.98e-314 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHLEJIOM_00990 7.65e-136 - - - - - - - -
MHLEJIOM_00991 6.04e-137 - - - - - - - -
MHLEJIOM_00992 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHLEJIOM_00993 7.87e-144 vanZ - - V - - - VanZ like family
MHLEJIOM_00994 4.66e-196 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
MHLEJIOM_00995 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
MHLEJIOM_00996 1.25e-163 - - - S - - - Domain of unknown function DUF1829
MHLEJIOM_00997 8.64e-63 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
MHLEJIOM_00999 1.39e-196 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MHLEJIOM_01000 9.67e-104 - - - S - - - Pfam Transposase IS66
MHLEJIOM_01001 1.6e-293 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
MHLEJIOM_01002 1.09e-220 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
MHLEJIOM_01003 5.68e-110 guaD - - FJ - - - MafB19-like deaminase
MHLEJIOM_01005 9.72e-32 int3 - - L - - - Belongs to the 'phage' integrase family
MHLEJIOM_01006 1.84e-161 - - - - - - - -
MHLEJIOM_01008 2.48e-140 - - - V - - - Abi-like protein
MHLEJIOM_01010 7.06e-102 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
MHLEJIOM_01011 1.53e-19 - - - - - - - -
MHLEJIOM_01012 4.42e-271 yttB - - EGP - - - Major Facilitator
MHLEJIOM_01013 5.09e-135 - - - S - - - Protein of unknown function (DUF1211)
MHLEJIOM_01014 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHLEJIOM_01017 1.49e-165 pgm7 - - G - - - Phosphoglycerate mutase family
MHLEJIOM_01018 2.61e-154 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_01019 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01020 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHLEJIOM_01021 1.44e-178 - - - S - - - NADPH-dependent FMN reductase
MHLEJIOM_01022 2.64e-208 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
MHLEJIOM_01023 5.06e-249 ampC - - V - - - Beta-lactamase
MHLEJIOM_01024 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
MHLEJIOM_01025 5.15e-142 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
MHLEJIOM_01026 8.62e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHLEJIOM_01027 3.85e-195 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHLEJIOM_01028 9.87e-238 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHLEJIOM_01029 1.57e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHLEJIOM_01030 3.05e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHLEJIOM_01031 1.23e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
MHLEJIOM_01032 2.57e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHLEJIOM_01033 1.13e-83 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHLEJIOM_01034 3.93e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHLEJIOM_01035 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHLEJIOM_01036 1.92e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHLEJIOM_01037 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHLEJIOM_01038 1.88e-91 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
MHLEJIOM_01039 8.38e-42 - - - S - - - Protein of unknown function (DUF1146)
MHLEJIOM_01040 4.12e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
MHLEJIOM_01041 1.37e-26 - - - S - - - DNA-directed RNA polymerase subunit beta
MHLEJIOM_01042 1.14e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
MHLEJIOM_01043 8.37e-42 - - - S - - - Protein of unknown function (DUF2969)
MHLEJIOM_01044 1.41e-285 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
MHLEJIOM_01045 4.19e-65 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
MHLEJIOM_01046 4.35e-282 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHLEJIOM_01047 1.88e-186 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHLEJIOM_01048 8.04e-192 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
MHLEJIOM_01049 2.09e-243 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHLEJIOM_01050 4.39e-148 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_01051 1.19e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
MHLEJIOM_01052 1.92e-243 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
MHLEJIOM_01053 2.41e-280 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHLEJIOM_01054 4.06e-102 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
MHLEJIOM_01055 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
MHLEJIOM_01056 4.73e-31 - - - - - - - -
MHLEJIOM_01057 9.85e-88 - - - S - - - Protein of unknown function (DUF1694)
MHLEJIOM_01058 3.03e-231 - - - S - - - Protein of unknown function (DUF2785)
MHLEJIOM_01059 3.03e-149 yhfA - - S - - - HAD hydrolase, family IA, variant 3
MHLEJIOM_01060 2.7e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
MHLEJIOM_01061 2.86e-108 uspA - - T - - - universal stress protein
MHLEJIOM_01062 1.93e-51 - - - - - - - -
MHLEJIOM_01064 1.37e-305 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
MHLEJIOM_01065 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
MHLEJIOM_01066 2.76e-99 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
MHLEJIOM_01067 2.85e-141 yktB - - S - - - Belongs to the UPF0637 family
MHLEJIOM_01068 1.02e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
MHLEJIOM_01069 4.62e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MHLEJIOM_01070 5.43e-157 - - - G - - - alpha-ribazole phosphatase activity
MHLEJIOM_01071 6.93e-198 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHLEJIOM_01072 1e-219 - - - IQ - - - NAD dependent epimerase/dehydratase family
MHLEJIOM_01073 2.93e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
MHLEJIOM_01074 2.05e-173 - - - F - - - deoxynucleoside kinase
MHLEJIOM_01075 8.16e-203 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
MHLEJIOM_01076 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHLEJIOM_01077 3.8e-197 - - - T - - - GHKL domain
MHLEJIOM_01078 2.69e-156 - - - T - - - Transcriptional regulatory protein, C terminal
MHLEJIOM_01079 3.75e-214 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHLEJIOM_01080 2.56e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_01081 5.48e-203 - - - K - - - Transcriptional regulator
MHLEJIOM_01082 1.91e-102 yphH - - S - - - Cupin domain
MHLEJIOM_01083 1.07e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
MHLEJIOM_01084 2.72e-149 - - - GM - - - NAD(P)H-binding
MHLEJIOM_01085 1.94e-54 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHLEJIOM_01086 1.93e-157 gst 2.5.1.18 - O ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 ko00000,ko00001,ko01000,ko02000 Glutathione S-transferase, C-terminal domain
MHLEJIOM_01087 6.11e-142 - - - K - - - Psort location Cytoplasmic, score
MHLEJIOM_01088 5.92e-170 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01089 1.76e-114 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01090 3.99e-197 degV - - S - - - Uncharacterised protein, DegV family COG1307
MHLEJIOM_01091 2.07e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MHLEJIOM_01092 2.43e-264 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHLEJIOM_01093 1.17e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
MHLEJIOM_01094 2.41e-203 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_01095 1.07e-281 - - - - - - - -
MHLEJIOM_01096 2.65e-89 - - - K - - - helix_turn_helix, mercury resistance
MHLEJIOM_01097 8.09e-65 - - - S - - - Protein of unknown function (DUF2568)
MHLEJIOM_01098 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
MHLEJIOM_01100 2.61e-49 - - - L - - - PFAM transposase, IS4 family protein
MHLEJIOM_01101 2.86e-87 - - - L - - - PFAM transposase, IS4 family protein
MHLEJIOM_01102 4.38e-35 - - - L - - - PFAM transposase, IS4 family protein
MHLEJIOM_01104 1.88e-42 - - - O - - - Torsin
MHLEJIOM_01105 0.000918 - - - - - - - -
MHLEJIOM_01106 3.57e-26 - - - S - - - FRG
MHLEJIOM_01107 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHLEJIOM_01108 7.1e-111 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
MHLEJIOM_01109 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHLEJIOM_01110 6.1e-272 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHLEJIOM_01111 2.45e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHLEJIOM_01112 1.24e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHLEJIOM_01113 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHLEJIOM_01114 6.01e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
MHLEJIOM_01115 1.98e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
MHLEJIOM_01116 1.97e-152 radC - - L ko:K03630 - ko00000 DNA repair protein
MHLEJIOM_01117 4.82e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
MHLEJIOM_01118 1.88e-191 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
MHLEJIOM_01119 1.23e-112 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
MHLEJIOM_01120 2.69e-148 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHLEJIOM_01121 8.63e-182 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
MHLEJIOM_01122 4.79e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHLEJIOM_01123 3.29e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
MHLEJIOM_01124 6.65e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
MHLEJIOM_01125 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHLEJIOM_01126 7.11e-60 - - - - - - - -
MHLEJIOM_01127 1.61e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
MHLEJIOM_01128 6.77e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHLEJIOM_01129 1.6e-68 ftsL - - D - - - cell division protein FtsL
MHLEJIOM_01130 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHLEJIOM_01131 1.33e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHLEJIOM_01132 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHLEJIOM_01133 4e-259 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHLEJIOM_01134 1.19e-199 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHLEJIOM_01135 1.44e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHLEJIOM_01136 3.25e-291 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHLEJIOM_01137 7.24e-102 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHLEJIOM_01138 5.58e-60 ylmG - - S ko:K02221 - ko00000,ko02044 integral membrane protein
MHLEJIOM_01139 4.15e-186 ylmH - - S - - - S4 domain protein
MHLEJIOM_01140 8.49e-120 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
MHLEJIOM_01141 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHLEJIOM_01142 4.62e-48 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
MHLEJIOM_01143 5.93e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
MHLEJIOM_01144 0.0 ydiC1 - - EGP - - - Major Facilitator
MHLEJIOM_01145 7.29e-270 yaaN - - P - - - Toxic anion resistance protein (TelA)
MHLEJIOM_01146 4.64e-150 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MHLEJIOM_01147 3.69e-124 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
MHLEJIOM_01148 1.42e-39 - - - - - - - -
MHLEJIOM_01149 1.95e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHLEJIOM_01150 3.99e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
MHLEJIOM_01151 1.21e-75 XK27_04120 - - S - - - Putative amino acid metabolism
MHLEJIOM_01152 0.0 uvrA2 - - L - - - ABC transporter
MHLEJIOM_01153 1.88e-316 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHLEJIOM_01155 4.69e-159 pgm6 - - G - - - phosphoglycerate mutase
MHLEJIOM_01156 5.41e-150 - - - S - - - repeat protein
MHLEJIOM_01157 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHLEJIOM_01158 2.86e-312 - - - S - - - Sterol carrier protein domain
MHLEJIOM_01159 1.63e-232 ytlR - - I - - - Diacylglycerol kinase catalytic domain
MHLEJIOM_01160 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHLEJIOM_01161 2.02e-43 ykzG - - S - - - Belongs to the UPF0356 family
MHLEJIOM_01162 1.11e-95 - - - - - - - -
MHLEJIOM_01163 1.73e-63 - - - - - - - -
MHLEJIOM_01164 4.82e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHLEJIOM_01165 5.13e-112 - - - S - - - E1-E2 ATPase
MHLEJIOM_01166 1.42e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MHLEJIOM_01167 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
MHLEJIOM_01168 0.0 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHLEJIOM_01169 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
MHLEJIOM_01170 4.32e-202 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
MHLEJIOM_01171 6.15e-62 yktA - - S - - - Belongs to the UPF0223 family
MHLEJIOM_01172 3.56e-189 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
MHLEJIOM_01173 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
MHLEJIOM_01174 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
MHLEJIOM_01175 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHLEJIOM_01176 8.46e-84 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
MHLEJIOM_01177 5.74e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
MHLEJIOM_01178 4.38e-113 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHLEJIOM_01179 1.05e-232 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
MHLEJIOM_01180 9.99e-146 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
MHLEJIOM_01181 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
MHLEJIOM_01182 5.08e-222 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
MHLEJIOM_01183 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
MHLEJIOM_01184 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHLEJIOM_01185 1.09e-61 - - - - - - - -
MHLEJIOM_01186 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHLEJIOM_01187 1.93e-213 - - - S - - - Tetratricopeptide repeat
MHLEJIOM_01188 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHLEJIOM_01190 5.78e-42 - - - M - - - Protein of unknown function (DUF3737)
MHLEJIOM_01191 4.5e-153 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
MHLEJIOM_01192 3.09e-80 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
MHLEJIOM_01193 1.24e-77 - - - K - - - helix_turn_helix, mercury resistance
MHLEJIOM_01194 0.0 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
MHLEJIOM_01195 9.55e-288 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHLEJIOM_01196 1.19e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHLEJIOM_01197 2.74e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
MHLEJIOM_01198 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
MHLEJIOM_01199 3.33e-28 - - - - - - - -
MHLEJIOM_01200 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHLEJIOM_01201 1.89e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01202 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHLEJIOM_01203 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
MHLEJIOM_01204 2.76e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MHLEJIOM_01205 2.78e-170 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
MHLEJIOM_01206 4.79e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHLEJIOM_01207 0.0 oatA - - I - - - Acyltransferase
MHLEJIOM_01208 2.71e-233 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHLEJIOM_01209 3.68e-183 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
MHLEJIOM_01210 2.47e-65 - - - S - - - Lipopolysaccharide assembly protein A domain
MHLEJIOM_01211 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHLEJIOM_01212 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
MHLEJIOM_01213 6.3e-123 - - - K - - - Domain of unknown function (DUF1836)
MHLEJIOM_01214 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
MHLEJIOM_01215 4.99e-184 - - - - - - - -
MHLEJIOM_01216 8.1e-36 - - - S - - - Protein of unknown function (DUF2929)
MHLEJIOM_01217 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
MHLEJIOM_01218 2.21e-227 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHLEJIOM_01219 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
MHLEJIOM_01220 4.31e-95 ytwI - - S - - - Protein of unknown function (DUF441)
MHLEJIOM_01221 1.71e-206 yitL - - S ko:K00243 - ko00000 S1 domain
MHLEJIOM_01222 8.18e-210 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
MHLEJIOM_01223 1.59e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHLEJIOM_01224 1.07e-159 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHLEJIOM_01225 8.74e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHLEJIOM_01226 3.15e-175 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
MHLEJIOM_01227 2.52e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHLEJIOM_01228 1.16e-60 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
MHLEJIOM_01229 4.84e-230 - - - S - - - Helix-turn-helix domain
MHLEJIOM_01230 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
MHLEJIOM_01231 1.68e-104 - - - M - - - Lysin motif
MHLEJIOM_01232 2.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
MHLEJIOM_01233 1.72e-303 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
MHLEJIOM_01234 1.5e-311 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
MHLEJIOM_01235 1.2e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHLEJIOM_01236 1.25e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
MHLEJIOM_01237 8.71e-200 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHLEJIOM_01238 2.16e-283 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHLEJIOM_01239 2.95e-110 - - - - - - - -
MHLEJIOM_01240 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01241 2e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHLEJIOM_01242 3.64e-119 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHLEJIOM_01243 1.83e-148 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
MHLEJIOM_01244 4.9e-190 WQ51_01275 - - S - - - EDD domain protein, DegV family
MHLEJIOM_01245 2.41e-196 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
MHLEJIOM_01246 3.18e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
MHLEJIOM_01247 1.52e-118 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHLEJIOM_01248 1.03e-54 yozE - - S - - - Belongs to the UPF0346 family
MHLEJIOM_01249 4.3e-316 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
MHLEJIOM_01250 9.79e-48 XK27_02555 - - - - - - -
MHLEJIOM_01251 6.8e-77 - - - S - - - Psort location Cytoplasmic, score
MHLEJIOM_01252 1.4e-06 - - - - - - - -
MHLEJIOM_01253 7.62e-47 - - - - - - - -
MHLEJIOM_01254 3.46e-242 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
MHLEJIOM_01255 6.29e-180 - - - K - - - Helix-turn-helix domain
MHLEJIOM_01256 1.03e-204 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHLEJIOM_01257 2.31e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHLEJIOM_01258 4.46e-187 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
MHLEJIOM_01259 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHLEJIOM_01260 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHLEJIOM_01261 1.66e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
MHLEJIOM_01262 2.06e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHLEJIOM_01263 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHLEJIOM_01264 5.38e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
MHLEJIOM_01265 6.92e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHLEJIOM_01267 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHLEJIOM_01268 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHLEJIOM_01269 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
MHLEJIOM_01270 2.56e-217 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHLEJIOM_01271 2.6e-232 - - - K - - - LysR substrate binding domain
MHLEJIOM_01272 3.24e-220 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
MHLEJIOM_01273 2.86e-267 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
MHLEJIOM_01274 7.18e-79 - - - - - - - -
MHLEJIOM_01275 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
MHLEJIOM_01276 2.68e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01277 7.03e-219 kinG - - T - - - Histidine kinase-like ATPases
MHLEJIOM_01278 2.9e-158 - - - T - - - Transcriptional regulatory protein, C terminal
MHLEJIOM_01279 5.52e-243 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MHLEJIOM_01280 1.24e-63 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01281 4.25e-94 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01282 1.19e-143 - - - C - - - Nitroreductase family
MHLEJIOM_01283 2.41e-260 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHLEJIOM_01284 6.09e-70 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
MHLEJIOM_01285 1.01e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MHLEJIOM_01286 1.42e-169 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHLEJIOM_01287 9.27e-159 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHLEJIOM_01288 1.4e-145 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHLEJIOM_01289 3.22e-135 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
MHLEJIOM_01290 4.62e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHLEJIOM_01291 2.06e-144 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHLEJIOM_01292 3.83e-278 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHLEJIOM_01293 3.29e-259 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHLEJIOM_01294 2.36e-129 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
MHLEJIOM_01295 2.95e-205 - - - S - - - EDD domain protein, DegV family
MHLEJIOM_01296 0.0 FbpA - - K - - - Fibronectin-binding protein
MHLEJIOM_01297 8.55e-67 - - - S - - - MazG-like family
MHLEJIOM_01298 8.21e-250 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHLEJIOM_01299 2.13e-227 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHLEJIOM_01300 3.52e-278 bfmBB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MHLEJIOM_01301 4.33e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
MHLEJIOM_01302 9.14e-239 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
MHLEJIOM_01303 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
MHLEJIOM_01304 6.69e-263 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Acetokinase family
MHLEJIOM_01305 1.74e-190 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
MHLEJIOM_01306 2.06e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHLEJIOM_01307 4.62e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHLEJIOM_01308 2.7e-198 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHLEJIOM_01309 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
MHLEJIOM_01310 2.17e-266 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
MHLEJIOM_01311 4.21e-304 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHLEJIOM_01312 7.64e-229 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
MHLEJIOM_01313 1.64e-299 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
MHLEJIOM_01314 6.08e-125 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHLEJIOM_01315 5.18e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHLEJIOM_01316 2.41e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHLEJIOM_01317 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
MHLEJIOM_01318 8.5e-61 - - - S - - - Family of unknown function (DUF5322)
MHLEJIOM_01319 2.37e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
MHLEJIOM_01320 2.09e-143 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
MHLEJIOM_01321 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHLEJIOM_01322 3.85e-63 - - - - - - - -
MHLEJIOM_01323 0.0 - - - S - - - Mga helix-turn-helix domain
MHLEJIOM_01324 8.72e-52 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
MHLEJIOM_01325 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHLEJIOM_01326 8.83e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHLEJIOM_01327 3.31e-207 lysR - - K - - - Transcriptional regulator
MHLEJIOM_01328 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
MHLEJIOM_01329 1e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
MHLEJIOM_01330 8.85e-47 - - - - - - - -
MHLEJIOM_01331 3e-221 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHLEJIOM_01332 6.61e-278 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
MHLEJIOM_01333 7.09e-88 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHLEJIOM_01334 6.54e-138 ypsA - - S - - - Belongs to the UPF0398 family
MHLEJIOM_01335 5.12e-157 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHLEJIOM_01336 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
MHLEJIOM_01337 5.94e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
MHLEJIOM_01338 7.61e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHLEJIOM_01339 3.19e-146 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
MHLEJIOM_01340 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
MHLEJIOM_01341 1.15e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
MHLEJIOM_01342 3.5e-112 ypmB - - S - - - Protein conserved in bacteria
MHLEJIOM_01343 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
MHLEJIOM_01344 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
MHLEJIOM_01345 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MHLEJIOM_01346 2.17e-214 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
MHLEJIOM_01347 1.28e-229 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
MHLEJIOM_01348 7.89e-245 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHLEJIOM_01349 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
MHLEJIOM_01350 4.61e-224 - - - - - - - -
MHLEJIOM_01351 6.41e-184 - - - - - - - -
MHLEJIOM_01352 2.32e-79 yitW - - S - - - Iron-sulfur cluster assembly protein
MHLEJIOM_01353 2.03e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
MHLEJIOM_01354 1.4e-191 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHLEJIOM_01355 1.14e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
MHLEJIOM_01356 2.63e-248 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHLEJIOM_01357 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHLEJIOM_01358 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
MHLEJIOM_01359 1.48e-219 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
MHLEJIOM_01360 1.5e-55 - - - - - - - -
MHLEJIOM_01361 1.04e-69 - - - - - - - -
MHLEJIOM_01362 5.8e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
MHLEJIOM_01363 2.76e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHLEJIOM_01364 1.38e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MHLEJIOM_01365 6.78e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
MHLEJIOM_01366 1.03e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHLEJIOM_01367 8.02e-230 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
MHLEJIOM_01368 1.81e-88 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
MHLEJIOM_01369 3.98e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
MHLEJIOM_01370 8.44e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHLEJIOM_01371 2.48e-210 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHLEJIOM_01372 3.1e-216 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHLEJIOM_01373 8.83e-107 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
MHLEJIOM_01374 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MHLEJIOM_01375 3.25e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
MHLEJIOM_01376 3.9e-48 XK27_04345 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
MHLEJIOM_01377 7.04e-217 - - - C - - - nadph quinone reductase
MHLEJIOM_01378 1.04e-99 - - - - - - - -
MHLEJIOM_01379 3.28e-190 - - - K - - - Helix-turn-helix
MHLEJIOM_01380 0.0 - - - - - - - -
MHLEJIOM_01381 2.31e-199 - - - V - - - ABC transporter
MHLEJIOM_01382 5.58e-108 - - - FG - - - adenosine 5'-monophosphoramidase activity
MHLEJIOM_01383 8.06e-314 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
MHLEJIOM_01384 5.5e-150 - - - J - - - HAD-hyrolase-like
MHLEJIOM_01385 1.59e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHLEJIOM_01386 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHLEJIOM_01387 5.49e-58 - - - - - - - -
MHLEJIOM_01388 7.37e-169 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHLEJIOM_01389 1.17e-220 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
MHLEJIOM_01390 3.49e-113 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
MHLEJIOM_01391 5.14e-143 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
MHLEJIOM_01392 2.23e-50 - - - - - - - -
MHLEJIOM_01393 8.05e-88 - - - S - - - Protein of unknown function (DUF1093)
MHLEJIOM_01394 8.67e-27 - - - - - - - -
MHLEJIOM_01395 1.72e-64 - - - - - - - -
MHLEJIOM_01396 5.39e-116 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01398 2.55e-142 - - - S - - - Flavodoxin-like fold
MHLEJIOM_01399 3.21e-123 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_01400 7.48e-193 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
MHLEJIOM_01401 6.77e-71 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
MHLEJIOM_01402 2.35e-117 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHLEJIOM_01403 1.7e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHLEJIOM_01404 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
MHLEJIOM_01405 8.85e-76 - - - - - - - -
MHLEJIOM_01406 2.05e-109 - - - S - - - ASCH
MHLEJIOM_01407 1.32e-33 - - - - - - - -
MHLEJIOM_01408 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHLEJIOM_01409 9.45e-261 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHLEJIOM_01410 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
MHLEJIOM_01411 3.18e-127 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHLEJIOM_01412 1.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHLEJIOM_01413 2.08e-286 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
MHLEJIOM_01414 7.37e-224 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
MHLEJIOM_01415 2.33e-212 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHLEJIOM_01416 7.4e-182 terC - - P - - - Integral membrane protein TerC family
MHLEJIOM_01417 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHLEJIOM_01418 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHLEJIOM_01419 1.29e-60 ylxQ - - J - - - ribosomal protein
MHLEJIOM_01420 3.23e-59 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
MHLEJIOM_01421 2.78e-275 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
MHLEJIOM_01422 1.33e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
MHLEJIOM_01423 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHLEJIOM_01424 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHLEJIOM_01425 3.52e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
MHLEJIOM_01426 7.66e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
MHLEJIOM_01427 5.24e-180 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHLEJIOM_01428 4.96e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHLEJIOM_01429 5.86e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
MHLEJIOM_01430 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHLEJIOM_01431 1.18e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
MHLEJIOM_01432 4.43e-60 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
MHLEJIOM_01433 4.13e-168 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
MHLEJIOM_01434 8.45e-160 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
MHLEJIOM_01435 3.91e-292 yhdG - - E ko:K03294 - ko00000 Amino Acid
MHLEJIOM_01436 2.47e-180 yejC - - S - - - Protein of unknown function (DUF1003)
MHLEJIOM_01437 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_01438 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_01439 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
MHLEJIOM_01440 2.84e-48 ynzC - - S - - - UPF0291 protein
MHLEJIOM_01441 3.28e-28 - - - - - - - -
MHLEJIOM_01442 2e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHLEJIOM_01443 1.76e-185 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
MHLEJIOM_01444 1.25e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHLEJIOM_01445 1.55e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
MHLEJIOM_01446 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
MHLEJIOM_01447 2.16e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHLEJIOM_01448 1.26e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHLEJIOM_01450 7.91e-70 - - - - - - - -
MHLEJIOM_01451 3.69e-232 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHLEJIOM_01452 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
MHLEJIOM_01453 2.8e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHLEJIOM_01454 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHLEJIOM_01455 1.8e-197 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_01456 3.2e-216 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_01457 5.65e-229 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_01458 4.24e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_01459 3.21e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHLEJIOM_01460 1.65e-240 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHLEJIOM_01461 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHLEJIOM_01462 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
MHLEJIOM_01463 5.83e-75 yloU - - S - - - Asp23 family, cell envelope-related function
MHLEJIOM_01464 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
MHLEJIOM_01465 4.35e-165 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
MHLEJIOM_01466 4.16e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
MHLEJIOM_01467 6.54e-220 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHLEJIOM_01468 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
MHLEJIOM_01469 5.22e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
MHLEJIOM_01470 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHLEJIOM_01471 1.13e-224 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHLEJIOM_01472 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHLEJIOM_01473 3.4e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHLEJIOM_01474 1.77e-47 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHLEJIOM_01475 2.52e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
MHLEJIOM_01476 1.65e-117 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
MHLEJIOM_01477 2.71e-66 - - - - - - - -
MHLEJIOM_01478 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
MHLEJIOM_01479 4.19e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHLEJIOM_01480 8.09e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
MHLEJIOM_01481 1.28e-189 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHLEJIOM_01482 1.42e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHLEJIOM_01483 7.39e-294 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHLEJIOM_01484 1.82e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHLEJIOM_01485 6.72e-88 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHLEJIOM_01486 9.44e-99 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
MHLEJIOM_01487 6.06e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHLEJIOM_01489 3.55e-258 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
MHLEJIOM_01490 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
MHLEJIOM_01491 1.77e-74 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
MHLEJIOM_01492 5.83e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
MHLEJIOM_01493 1.17e-16 - - - - - - - -
MHLEJIOM_01494 1.77e-33 - - - - - - - -
MHLEJIOM_01496 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MHLEJIOM_01497 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
MHLEJIOM_01498 1.32e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
MHLEJIOM_01499 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
MHLEJIOM_01500 7.84e-303 ynbB - - P - - - aluminum resistance
MHLEJIOM_01501 5.4e-223 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHLEJIOM_01502 3.33e-35 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
MHLEJIOM_01503 3.89e-96 yqhL - - P - - - Rhodanese-like protein
MHLEJIOM_01504 1.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
MHLEJIOM_01505 6.79e-55 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
MHLEJIOM_01506 5.43e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
MHLEJIOM_01507 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
MHLEJIOM_01508 0.0 - - - S - - - Bacterial membrane protein YfhO
MHLEJIOM_01509 1.15e-71 yneR - - S - - - Belongs to the HesB IscA family
MHLEJIOM_01510 2.04e-149 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
MHLEJIOM_01511 1.33e-231 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHLEJIOM_01512 3.14e-164 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
MHLEJIOM_01513 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHLEJIOM_01514 3.43e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
MHLEJIOM_01515 5.31e-265 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHLEJIOM_01516 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHLEJIOM_01517 3.55e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHLEJIOM_01518 1.2e-87 yodB - - K - - - Transcriptional regulator, HxlR family
MHLEJIOM_01519 3.09e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHLEJIOM_01520 4.47e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHLEJIOM_01521 4.17e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
MHLEJIOM_01522 8.99e-229 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHLEJIOM_01523 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHLEJIOM_01524 1.01e-157 csrR - - K - - - response regulator
MHLEJIOM_01525 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHLEJIOM_01526 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
MHLEJIOM_01527 2.27e-268 ylbM - - S - - - Belongs to the UPF0348 family
MHLEJIOM_01528 8.06e-177 yccK - - Q - - - ubiE/COQ5 methyltransferase family
MHLEJIOM_01529 1.18e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHLEJIOM_01530 3.21e-142 yqeK - - H - - - Hydrolase, HD family
MHLEJIOM_01531 2.72e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHLEJIOM_01532 3.95e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
MHLEJIOM_01533 3.02e-262 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
MHLEJIOM_01534 6.63e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
MHLEJIOM_01535 2.77e-220 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHLEJIOM_01536 2.74e-243 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHLEJIOM_01537 4.31e-157 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
MHLEJIOM_01538 7.15e-230 - - - C - - - Alcohol dehydrogenase GroES-like domain
MHLEJIOM_01539 8.27e-130 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
MHLEJIOM_01540 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHLEJIOM_01541 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
MHLEJIOM_01542 7.46e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHLEJIOM_01543 2.7e-166 - - - S - - - SseB protein N-terminal domain
MHLEJIOM_01544 4.35e-69 - - - - - - - -
MHLEJIOM_01545 1.17e-130 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
MHLEJIOM_01546 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHLEJIOM_01548 2.06e-180 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
MHLEJIOM_01549 1.73e-302 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
MHLEJIOM_01550 2.06e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHLEJIOM_01551 7.76e-130 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHLEJIOM_01552 1.7e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHLEJIOM_01553 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHLEJIOM_01554 2.55e-155 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
MHLEJIOM_01555 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
MHLEJIOM_01556 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
MHLEJIOM_01557 3.17e-149 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHLEJIOM_01558 5.32e-73 ytpP - - CO - - - Thioredoxin
MHLEJIOM_01559 3.03e-06 - - - S - - - Small secreted protein
MHLEJIOM_01560 1.35e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHLEJIOM_01561 4.51e-189 ytmP - - M - - - Choline/ethanolamine kinase
MHLEJIOM_01562 1.01e-275 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_01563 2.4e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01564 1.67e-99 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
MHLEJIOM_01565 5.77e-81 - - - S - - - YtxH-like protein
MHLEJIOM_01566 5.26e-205 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHLEJIOM_01567 8.42e-232 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHLEJIOM_01568 1.03e-72 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
MHLEJIOM_01569 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
MHLEJIOM_01570 1.3e-198 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
MHLEJIOM_01571 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
MHLEJIOM_01572 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
MHLEJIOM_01574 1.97e-88 - - - - - - - -
MHLEJIOM_01575 1.16e-31 - - - - - - - -
MHLEJIOM_01576 3.67e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
MHLEJIOM_01577 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
MHLEJIOM_01578 1.44e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MHLEJIOM_01579 1.13e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHLEJIOM_01580 3.28e-176 yhfI - - S - - - Metallo-beta-lactamase superfamily
MHLEJIOM_01581 4.56e-120 traP 1.14.99.57, 6.2.1.3 - S ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 heme oxygenase (decyclizing) activity
MHLEJIOM_01582 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
MHLEJIOM_01583 1.14e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_01584 1.57e-159 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
MHLEJIOM_01585 1.58e-262 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
MHLEJIOM_01586 1.54e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHLEJIOM_01587 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
MHLEJIOM_01588 1.17e-100 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
MHLEJIOM_01589 1.57e-299 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
MHLEJIOM_01590 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
MHLEJIOM_01591 1.12e-128 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHLEJIOM_01592 1.98e-234 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
MHLEJIOM_01593 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHLEJIOM_01594 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHLEJIOM_01595 2.51e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHLEJIOM_01596 7.25e-56 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHLEJIOM_01597 1.63e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
MHLEJIOM_01598 1e-272 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHLEJIOM_01599 2.66e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHLEJIOM_01600 6.68e-136 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
MHLEJIOM_01601 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MHLEJIOM_01602 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHLEJIOM_01603 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
MHLEJIOM_01604 9.5e-39 - - - - - - - -
MHLEJIOM_01605 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
MHLEJIOM_01606 3.36e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
MHLEJIOM_01608 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHLEJIOM_01609 1.44e-311 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
MHLEJIOM_01610 3.99e-260 yueF - - S - - - AI-2E family transporter
MHLEJIOM_01611 1.61e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01612 3.88e-123 - - - - - - - -
MHLEJIOM_01613 1.1e-134 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
MHLEJIOM_01614 6.84e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
MHLEJIOM_01615 0.0 frvR - - K ko:K02538,ko:K03483,ko:K09685,ko:K18531 - ko00000,ko03000 transcriptional antiterminator
MHLEJIOM_01616 6.46e-83 - - - - - - - -
MHLEJIOM_01617 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHLEJIOM_01618 1.68e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MHLEJIOM_01619 2.13e-172 - - - K ko:K03489 - ko00000,ko03000 UTRA
MHLEJIOM_01620 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHLEJIOM_01621 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_01622 2.36e-111 - - - - - - - -
MHLEJIOM_01623 7.89e-66 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHLEJIOM_01624 6.27e-67 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_01625 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHLEJIOM_01626 2.14e-278 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
MHLEJIOM_01627 4.66e-267 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
MHLEJIOM_01628 9.92e-266 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
MHLEJIOM_01629 7.23e-66 - - - - - - - -
MHLEJIOM_01630 9.55e-205 - - - G - - - Xylose isomerase domain protein TIM barrel
MHLEJIOM_01631 4.27e-132 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
MHLEJIOM_01632 4.35e-199 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 converts alpha-aldose to the beta-anomer
MHLEJIOM_01633 3.11e-271 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
MHLEJIOM_01634 4.33e-132 - - - S - - - ECF transporter, substrate-specific component
MHLEJIOM_01636 1.15e-104 - - - K - - - Acetyltransferase GNAT Family
MHLEJIOM_01637 1.65e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
MHLEJIOM_01638 2.36e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01639 2.83e-188 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
MHLEJIOM_01640 1.43e-197 XK27_08835 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_01641 1.17e-95 - - - - - - - -
MHLEJIOM_01642 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHLEJIOM_01643 2.8e-277 - - - V - - - Beta-lactamase
MHLEJIOM_01644 2.51e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHLEJIOM_01645 1.57e-280 - - - V - - - Beta-lactamase
MHLEJIOM_01646 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHLEJIOM_01647 1.62e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHLEJIOM_01648 7.45e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHLEJIOM_01649 1.13e-177 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHLEJIOM_01650 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
MHLEJIOM_01653 2.43e-202 - - - S - - - Calcineurin-like phosphoesterase
MHLEJIOM_01654 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
MHLEJIOM_01655 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01656 1.71e-87 - - - - - - - -
MHLEJIOM_01657 6.13e-100 - - - S - - - function, without similarity to other proteins
MHLEJIOM_01658 0.0 - - - G - - - MFS/sugar transport protein
MHLEJIOM_01659 6.47e-293 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MHLEJIOM_01660 8.15e-77 - - - - - - - -
MHLEJIOM_01661 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
MHLEJIOM_01662 6.28e-25 - - - S - - - Virus attachment protein p12 family
MHLEJIOM_01663 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
MHLEJIOM_01664 2.94e-60 feoA - - P ko:K04758 - ko00000,ko02000 FeoA
MHLEJIOM_01665 5.32e-23 - - - P ko:K04758 - ko00000,ko02000 FeoA
MHLEJIOM_01666 2.36e-167 - - - E - - - lipolytic protein G-D-S-L family
MHLEJIOM_01669 3.72e-152 - - - S ko:K07118 - ko00000 NAD(P)H-binding
MHLEJIOM_01670 8.14e-79 - - - S - - - MucBP domain
MHLEJIOM_01671 2.63e-97 - - - - - - - -
MHLEJIOM_01672 7.71e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHLEJIOM_01673 0.0 - - - K - - - Mga helix-turn-helix domain
MHLEJIOM_01674 0.0 - - - K - - - Mga helix-turn-helix domain
MHLEJIOM_01675 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
MHLEJIOM_01676 2.4e-169 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
MHLEJIOM_01677 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
MHLEJIOM_01678 4.81e-127 - - - - - - - -
MHLEJIOM_01679 1.2e-127 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHLEJIOM_01680 4.97e-248 - - - S - - - Protein of unknown function C-terminal (DUF3324)
MHLEJIOM_01681 8.02e-114 - - - - - - - -
MHLEJIOM_01682 1.43e-25 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHLEJIOM_01683 1.03e-150 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MHLEJIOM_01684 2.86e-204 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
MHLEJIOM_01685 1.25e-201 - - - I - - - alpha/beta hydrolase fold
MHLEJIOM_01686 1.83e-40 - - - - - - - -
MHLEJIOM_01687 7.43e-97 - - - - - - - -
MHLEJIOM_01688 5.7e-199 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MHLEJIOM_01689 4.14e-163 citR - - K - - - FCD
MHLEJIOM_01690 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
MHLEJIOM_01691 4.61e-120 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MHLEJIOM_01692 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
MHLEJIOM_01693 8.71e-200 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
MHLEJIOM_01694 3.41e-65 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
MHLEJIOM_01695 2.88e-226 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MHLEJIOM_01696 3.26e-07 - - - - - - - -
MHLEJIOM_01697 1.13e-250 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
MHLEJIOM_01698 1.71e-62 oadG - - I - - - Biotin-requiring enzyme
MHLEJIOM_01699 2.14e-69 - - - - - - - -
MHLEJIOM_01700 4.1e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
MHLEJIOM_01701 3.61e-55 - - - - - - - -
MHLEJIOM_01702 2.68e-135 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MHLEJIOM_01703 2.1e-114 - - - K - - - GNAT family
MHLEJIOM_01704 4.31e-134 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
MHLEJIOM_01705 1.13e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHLEJIOM_01706 4.93e-113 ORF00048 - - - - - - -
MHLEJIOM_01707 6.35e-177 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
MHLEJIOM_01708 1.93e-214 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_01709 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
MHLEJIOM_01710 4e-147 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
MHLEJIOM_01711 0.0 - - - EGP - - - Major Facilitator
MHLEJIOM_01712 1.65e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
MHLEJIOM_01713 1.18e-230 - - - K - - - Helix-turn-helix XRE-family like proteins
MHLEJIOM_01714 4.73e-209 - - - S - - - Alpha beta hydrolase
MHLEJIOM_01715 2.73e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
MHLEJIOM_01716 2.19e-159 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_01717 1.32e-15 - - - - - - - -
MHLEJIOM_01718 7.65e-176 - - - - - - - -
MHLEJIOM_01719 6.09e-112 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_01720 6.35e-126 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHLEJIOM_01721 2.83e-205 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
MHLEJIOM_01722 4.63e-253 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
MHLEJIOM_01724 2.38e-226 - - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHLEJIOM_01725 9.89e-214 - - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_01726 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
MHLEJIOM_01727 1.19e-164 - - - S - - - DJ-1/PfpI family
MHLEJIOM_01728 6.09e-70 - - - K - - - Transcriptional
MHLEJIOM_01729 7.53e-49 - - - - - - - -
MHLEJIOM_01730 1.17e-283 - - - V - - - ABC transporter transmembrane region
MHLEJIOM_01731 1.01e-45 - - - V - - - ABC transporter transmembrane region
MHLEJIOM_01732 0.0 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
MHLEJIOM_01734 4.6e-89 - - - S - - - Iron-sulphur cluster biosynthesis
MHLEJIOM_01735 2.13e-73 - 2.7.1.39 - S ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Phosphotransferase enzyme family
MHLEJIOM_01736 9.36e-34 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
MHLEJIOM_01738 6.61e-26 - - - M - - - LysM domain
MHLEJIOM_01739 6.22e-169 - - - M - - - LysM domain
MHLEJIOM_01740 1.93e-91 - - - M - - - LysM domain
MHLEJIOM_01741 2.28e-171 zmp3 - - O - - - Zinc-dependent metalloprotease
MHLEJIOM_01742 3.77e-171 - - - K - - - DeoR C terminal sensor domain
MHLEJIOM_01744 3.29e-173 ydcL - - L - - - Belongs to the 'phage' integrase family
MHLEJIOM_01745 1.05e-17 - - - S - - - Domain of unknown function (DUF3173)
MHLEJIOM_01746 1.32e-79 - - - - - - - -
MHLEJIOM_01747 3.33e-114 - - - D - - - ftsk spoiiie
MHLEJIOM_01751 2.08e-186 - - - L - - - HNH endonuclease
MHLEJIOM_01752 1.01e-132 - - - S - - - Adenine-specific methyltransferase EcoRI
MHLEJIOM_01753 1.45e-55 - - - S - - - Abortive infection C-terminus
MHLEJIOM_01754 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
MHLEJIOM_01755 3.27e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
MHLEJIOM_01757 1.38e-55 - - - - - - - -
MHLEJIOM_01758 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHLEJIOM_01759 8.34e-109 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
MHLEJIOM_01760 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
MHLEJIOM_01761 4.33e-29 - - - - - - - -
MHLEJIOM_01762 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
MHLEJIOM_01763 1.97e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHLEJIOM_01764 1.51e-104 yjhE - - S - - - Phage tail protein
MHLEJIOM_01765 5.16e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHLEJIOM_01766 1.16e-239 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
MHLEJIOM_01767 4.03e-164 gpm2 - - G - - - Phosphoglycerate mutase family
MHLEJIOM_01768 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHLEJIOM_01769 1.09e-173 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01770 0.0 - - - E - - - Amino Acid
MHLEJIOM_01771 2.34e-209 - - - I - - - Diacylglycerol kinase catalytic domain
MHLEJIOM_01772 4.57e-304 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHLEJIOM_01773 5.91e-202 nodB3 - - G - - - Polysaccharide deacetylase
MHLEJIOM_01774 0.0 - - - M - - - Sulfatase
MHLEJIOM_01775 8.04e-220 - - - S - - - EpsG family
MHLEJIOM_01776 1.81e-99 - - - D - - - Capsular exopolysaccharide family
MHLEJIOM_01777 9.82e-118 ywqC - - M ko:K16554 ko05111,map05111 ko00000,ko00001,ko02000 capsule polysaccharide biosynthetic process
MHLEJIOM_01778 3.04e-305 - - - S - - - polysaccharide biosynthetic process
MHLEJIOM_01779 4.4e-244 - - - M - - - Glycosyl transferases group 1
MHLEJIOM_01780 1.05e-126 tagF 2.7.8.12 - M ko:K09809,ko:K19046 - ko00000,ko01000,ko02048 Glycosyl transferase, family 2
MHLEJIOM_01781 4.8e-77 - - - S - - - Psort location CytoplasmicMembrane, score
MHLEJIOM_01782 2.07e-295 - - - S - - - Bacterial membrane protein, YfhO
MHLEJIOM_01783 0.0 - - - M - - - Glycosyl hydrolases family 25
MHLEJIOM_01784 1.27e-220 - - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
MHLEJIOM_01785 2.04e-145 - - - M - - - Acyltransferase family
MHLEJIOM_01786 2.37e-199 ykoT - - M - - - Glycosyl transferase family 2
MHLEJIOM_01787 2.13e-252 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHLEJIOM_01788 2.14e-118 - - - - - - - -
MHLEJIOM_01789 4.82e-310 cps2E - - M - - - Bacterial sugar transferase
MHLEJIOM_01790 5.34e-162 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MHLEJIOM_01791 5.55e-139 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
MHLEJIOM_01792 7.67e-224 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
MHLEJIOM_01793 6.51e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_01794 1.44e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_01795 2.05e-189 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
MHLEJIOM_01796 2.59e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_01797 8.97e-227 - - - - - - - -
MHLEJIOM_01799 3.91e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
MHLEJIOM_01800 9.35e-15 - - - - - - - -
MHLEJIOM_01801 7.28e-144 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
MHLEJIOM_01802 6.72e-88 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_01803 2.08e-187 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
MHLEJIOM_01804 1.55e-312 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHLEJIOM_01805 1.32e-221 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHLEJIOM_01806 5.83e-73 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
MHLEJIOM_01807 3.12e-222 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHLEJIOM_01808 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHLEJIOM_01809 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHLEJIOM_01810 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHLEJIOM_01811 9.81e-280 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
MHLEJIOM_01812 1.18e-255 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHLEJIOM_01813 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHLEJIOM_01814 8.73e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
MHLEJIOM_01815 6.74e-134 - - - M - - - Sortase family
MHLEJIOM_01816 1.29e-186 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHLEJIOM_01817 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
MHLEJIOM_01818 1.94e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
MHLEJIOM_01819 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
MHLEJIOM_01820 1.15e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
MHLEJIOM_01821 5.65e-201 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHLEJIOM_01822 0.0 - - - L - - - Transposase DDE domain
MHLEJIOM_01823 2.16e-203 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MHLEJIOM_01824 2.4e-258 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHLEJIOM_01825 3.12e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MHLEJIOM_01826 1.53e-208 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MHLEJIOM_01827 6.81e-93 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
MHLEJIOM_01828 1.88e-176 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
MHLEJIOM_01829 4.55e-305 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
MHLEJIOM_01830 1.07e-139 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
MHLEJIOM_01831 1.82e-207 - - - S - - - O-antigen ligase like membrane protein
MHLEJIOM_01832 2.26e-176 - - - M - - - Glycosyltransferase like family 2
MHLEJIOM_01833 4.01e-261 - - - M - - - Glycosyl transferases group 1
MHLEJIOM_01834 3.64e-293 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
MHLEJIOM_01835 1.2e-161 ywqD - - D - - - Capsular exopolysaccharide family
MHLEJIOM_01836 7.89e-184 epsB - - M - - - biosynthesis protein
MHLEJIOM_01837 2.13e-169 - - - E - - - lipolytic protein G-D-S-L family
MHLEJIOM_01838 8.13e-104 ccl - - S - - - QueT transporter
MHLEJIOM_01839 2.57e-160 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
MHLEJIOM_01840 8.55e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
MHLEJIOM_01841 1.32e-63 - - - K - - - sequence-specific DNA binding
MHLEJIOM_01842 6.17e-151 gpm5 - - G - - - Phosphoglycerate mutase family
MHLEJIOM_01843 2.59e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_01844 4.99e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_01845 3.01e-227 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHLEJIOM_01846 1.4e-208 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHLEJIOM_01847 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHLEJIOM_01848 0.0 - - - EGP - - - Major Facilitator Superfamily
MHLEJIOM_01849 4.1e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHLEJIOM_01850 1.34e-170 lutC - - S ko:K00782 - ko00000 LUD domain
MHLEJIOM_01851 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
MHLEJIOM_01852 1.7e-190 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
MHLEJIOM_01853 2.39e-109 - - - - - - - -
MHLEJIOM_01854 6.31e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
MHLEJIOM_01855 4.24e-211 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MHLEJIOM_01856 2.68e-89 - - - S - - - Domain of unknown function (DUF3284)
MHLEJIOM_01858 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_01859 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
MHLEJIOM_01860 1.05e-173 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
MHLEJIOM_01861 1.76e-177 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
MHLEJIOM_01862 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
MHLEJIOM_01863 7.21e-102 - - - - - - - -
MHLEJIOM_01864 9.27e-77 - - - S - - - WxL domain surface cell wall-binding
MHLEJIOM_01865 1.09e-182 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
MHLEJIOM_01866 1.75e-129 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
MHLEJIOM_01867 7.21e-171 - - - - - - - -
MHLEJIOM_01868 0.0 - - - S - - - Protein of unknown function (DUF1524)
MHLEJIOM_01869 6.53e-82 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHLEJIOM_01870 4.99e-223 - - - L - - - Belongs to the 'phage' integrase family
MHLEJIOM_01871 2.16e-89 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
MHLEJIOM_01872 3.89e-252 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
MHLEJIOM_01873 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
MHLEJIOM_01874 3.02e-96 - - - - - - - -
MHLEJIOM_01875 3.5e-271 - - - - - - - -
MHLEJIOM_01876 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHLEJIOM_01877 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHLEJIOM_01878 1.01e-230 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
MHLEJIOM_01879 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
MHLEJIOM_01880 7e-210 - - - GM - - - NmrA-like family
MHLEJIOM_01881 3.95e-297 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
MHLEJIOM_01882 3.41e-184 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
MHLEJIOM_01883 8.74e-194 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHLEJIOM_01884 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
MHLEJIOM_01885 3.23e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHLEJIOM_01886 8.8e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHLEJIOM_01887 6.98e-284 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHLEJIOM_01888 8.26e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
MHLEJIOM_01889 2.07e-210 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
MHLEJIOM_01890 1.07e-218 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
MHLEJIOM_01891 1.38e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHLEJIOM_01892 3.96e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHLEJIOM_01893 2.44e-99 - - - K - - - Winged helix DNA-binding domain
MHLEJIOM_01894 6.79e-95 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
MHLEJIOM_01895 1.47e-245 - - - E - - - Alpha/beta hydrolase family
MHLEJIOM_01896 3.76e-288 - - - C - - - Iron-containing alcohol dehydrogenase
MHLEJIOM_01897 1.64e-62 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
MHLEJIOM_01898 2.84e-88 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
MHLEJIOM_01899 2.67e-13 tcaA - - S ko:K21463 - ko00000 response to antibiotic
MHLEJIOM_01900 9.75e-214 - - - S - - - Putative esterase
MHLEJIOM_01901 1.06e-255 - - - - - - - -
MHLEJIOM_01902 1.47e-136 - - - K - - - Transcriptional regulator, MarR family
MHLEJIOM_01903 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
MHLEJIOM_01904 6.6e-106 - - - F - - - NUDIX domain
MHLEJIOM_01905 1.91e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHLEJIOM_01906 4.74e-30 - - - - - - - -
MHLEJIOM_01907 3.65e-208 - - - S - - - zinc-ribbon domain
MHLEJIOM_01908 1.2e-261 pbpX - - V - - - Beta-lactamase
MHLEJIOM_01909 4.01e-240 ydbI - - K - - - AI-2E family transporter
MHLEJIOM_01910 4.31e-166 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHLEJIOM_01911 1.41e-85 gtcA2 - - S - - - Teichoic acid glycosylation protein
MHLEJIOM_01912 7.62e-219 - - - I - - - Diacylglycerol kinase catalytic domain
MHLEJIOM_01913 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
MHLEJIOM_01914 3.51e-216 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHLEJIOM_01915 4.78e-188 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
MHLEJIOM_01916 9.19e-285 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
MHLEJIOM_01917 1.39e-176 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
MHLEJIOM_01918 2.6e-96 usp1 - - T - - - Universal stress protein family
MHLEJIOM_01919 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
MHLEJIOM_01920 2.89e-191 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHLEJIOM_01921 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
MHLEJIOM_01922 2.77e-291 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
MHLEJIOM_01923 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
MHLEJIOM_01924 9.21e-270 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
MHLEJIOM_01925 1.32e-51 - - - - - - - -
MHLEJIOM_01926 2.9e-220 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHLEJIOM_01927 2.05e-225 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHLEJIOM_01928 3.99e-278 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
MHLEJIOM_01930 7.26e-58 - - - - - - - -
MHLEJIOM_01931 1.5e-162 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
MHLEJIOM_01932 1.62e-93 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
MHLEJIOM_01933 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
MHLEJIOM_01935 2.21e-258 - - - S - - - Calcineurin-like phosphoesterase
MHLEJIOM_01936 4.15e-204 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHLEJIOM_01937 3.26e-226 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHLEJIOM_01938 1.92e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHLEJIOM_01939 9.96e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
MHLEJIOM_01940 2.14e-279 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_01941 6.81e-86 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHLEJIOM_01942 9.19e-209 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_01943 2.04e-141 - - - I - - - ABC-2 family transporter protein
MHLEJIOM_01944 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
MHLEJIOM_01945 1.24e-258 ald1 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
MHLEJIOM_01946 1.02e-236 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MHLEJIOM_01947 0.0 - - - S - - - OPT oligopeptide transporter protein
MHLEJIOM_01948 3.4e-82 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
MHLEJIOM_01949 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
MHLEJIOM_01950 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
MHLEJIOM_01951 8.81e-317 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
MHLEJIOM_01952 8.23e-126 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
MHLEJIOM_01953 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHLEJIOM_01954 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
MHLEJIOM_01955 4.16e-199 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
MHLEJIOM_01956 0.0 msbA9 - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MHLEJIOM_01957 0.0 cydD1 - - CO ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
MHLEJIOM_01958 2.59e-97 - - - S - - - NusG domain II
MHLEJIOM_01959 4.73e-209 - - - M - - - Peptidoglycan-binding domain 1 protein
MHLEJIOM_01960 2.28e-148 - - - S - - - CRISPR-associated protein (Cas_Csn2)
MHLEJIOM_01961 2.84e-62 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHLEJIOM_01962 3.9e-212 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHLEJIOM_01963 0.0 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MHLEJIOM_01964 3.96e-182 - - - - - - - -
MHLEJIOM_01965 3.11e-274 - - - S - - - Membrane
MHLEJIOM_01966 3.22e-82 - - - S - - - Protein of unknown function (DUF1093)
MHLEJIOM_01967 6.43e-66 - - - - - - - -
MHLEJIOM_01968 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MHLEJIOM_01969 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MHLEJIOM_01970 2.5e-233 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
MHLEJIOM_01971 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
MHLEJIOM_01972 8.2e-304 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
MHLEJIOM_01973 7.59e-245 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MHLEJIOM_01974 6.98e-53 - - - - - - - -
MHLEJIOM_01975 1.22e-112 - - - - - - - -
MHLEJIOM_01976 6.71e-34 - - - - - - - -
MHLEJIOM_01977 1.72e-213 - - - EG - - - EamA-like transporter family
MHLEJIOM_01978 1.64e-142 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
MHLEJIOM_01979 3.25e-74 - - - K - - - Helix-turn-helix domain
MHLEJIOM_01980 2.6e-186 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
MHLEJIOM_01981 3.18e-285 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
MHLEJIOM_01982 1.54e-84 - - - - - - - -
MHLEJIOM_01983 7.09e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
MHLEJIOM_01984 5.77e-93 adhR - - K - - - helix_turn_helix, mercury resistance
MHLEJIOM_01985 4.3e-106 - - - C - - - Flavodoxin
MHLEJIOM_01986 1.81e-251 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
MHLEJIOM_01987 6.48e-147 - - - GM - - - NmrA-like family
MHLEJIOM_01988 1.68e-31 - - - S - - - Protein of unknown function (DUF1211)
MHLEJIOM_01990 2.29e-131 - - - Q - - - methyltransferase
MHLEJIOM_01991 5.87e-133 - - - T - - - Sh3 type 3 domain protein
MHLEJIOM_01992 3.89e-151 - - - F - - - glutamine amidotransferase
MHLEJIOM_01993 5.22e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
MHLEJIOM_01994 0.0 yhdP - - S - - - Transporter associated domain
MHLEJIOM_01995 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
MHLEJIOM_01996 8.38e-80 - - - S - - - Domain of unknown function (DUF4811)
MHLEJIOM_01997 4.8e-128 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
MHLEJIOM_01998 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHLEJIOM_01999 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHLEJIOM_02000 0.0 ydaO - - E - - - amino acid
MHLEJIOM_02001 6.55e-75 - - - S - - - Domain of unknown function (DUF1827)
MHLEJIOM_02002 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHLEJIOM_02003 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHLEJIOM_02004 6.1e-143 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHLEJIOM_02005 1.18e-250 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
MHLEJIOM_02006 9.44e-236 - - - - - - - -
MHLEJIOM_02007 1.39e-202 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_02008 4.97e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
MHLEJIOM_02009 1.1e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHLEJIOM_02010 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
MHLEJIOM_02011 3.12e-68 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_02012 9.93e-242 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHLEJIOM_02013 8.44e-130 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
MHLEJIOM_02014 3.82e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
MHLEJIOM_02015 1.7e-95 - - - - - - - -
MHLEJIOM_02016 2.42e-117 - - - T - - - ECF transporter, substrate-specific component
MHLEJIOM_02017 6.13e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MHLEJIOM_02018 3.86e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
MHLEJIOM_02019 2.43e-182 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHLEJIOM_02020 7.92e-76 yabA - - L - - - Involved in initiation control of chromosome replication
MHLEJIOM_02021 2.66e-222 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
MHLEJIOM_02022 1.14e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
MHLEJIOM_02023 4.16e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHLEJIOM_02024 1.71e-45 - - - S - - - Protein of unknown function (DUF2508)
MHLEJIOM_02025 7.27e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHLEJIOM_02026 7e-49 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHLEJIOM_02027 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHLEJIOM_02028 1.79e-117 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHLEJIOM_02029 9.05e-67 - - - - - - - -
MHLEJIOM_02030 1.41e-140 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
MHLEJIOM_02031 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHLEJIOM_02032 1.15e-59 - - - - - - - -
MHLEJIOM_02033 1.49e-225 ccpB - - K - - - lacI family
MHLEJIOM_02034 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
MHLEJIOM_02035 1.98e-204 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHLEJIOM_02036 1.37e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHLEJIOM_02037 7.23e-108 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHLEJIOM_02038 1.92e-283 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
MHLEJIOM_02039 9.19e-195 - - - K - - - acetyltransferase
MHLEJIOM_02040 5.94e-87 - - - - - - - -
MHLEJIOM_02041 1.19e-277 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
MHLEJIOM_02042 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
MHLEJIOM_02043 1.89e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHLEJIOM_02044 6.87e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHLEJIOM_02045 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
MHLEJIOM_02046 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
MHLEJIOM_02047 1.04e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
MHLEJIOM_02048 1.7e-117 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
MHLEJIOM_02049 1.36e-125 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
MHLEJIOM_02050 4.31e-83 - - - S - - - Domain of unknown function (DUF4430)
MHLEJIOM_02051 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
MHLEJIOM_02052 3.77e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
MHLEJIOM_02053 1.71e-205 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
MHLEJIOM_02054 2.29e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
MHLEJIOM_02055 2.09e-30 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHLEJIOM_02056 4.4e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
MHLEJIOM_02057 5.34e-219 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
MHLEJIOM_02058 2.85e-215 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
MHLEJIOM_02059 2.57e-251 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHLEJIOM_02060 6.86e-187 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
MHLEJIOM_02061 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
MHLEJIOM_02062 3.92e-104 - - - S - - - NusG domain II
MHLEJIOM_02063 1.03e-127 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
MHLEJIOM_02064 1.23e-227 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
MHLEJIOM_02067 1.33e-157 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
MHLEJIOM_02068 3.64e-249 XK27_00915 - - C - - - Luciferase-like monooxygenase
MHLEJIOM_02069 2.34e-153 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_02070 2.62e-220 - - - - - - - -
MHLEJIOM_02071 2.11e-142 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHLEJIOM_02072 1.93e-13 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHLEJIOM_02074 1.05e-127 - - - - - - - -
MHLEJIOM_02075 1.45e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
MHLEJIOM_02076 2.21e-181 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHLEJIOM_02077 4.83e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHLEJIOM_02078 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHLEJIOM_02079 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
MHLEJIOM_02080 5.14e-137 - - - - - - - -
MHLEJIOM_02082 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHLEJIOM_02083 7.79e-236 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
MHLEJIOM_02084 3.02e-152 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MHLEJIOM_02085 7.02e-182 - - - K - - - SIS domain
MHLEJIOM_02086 2.26e-146 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
MHLEJIOM_02087 1.31e-224 - - - S - - - Membrane
MHLEJIOM_02088 5.31e-82 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
MHLEJIOM_02089 1.17e-286 inlJ - - M - - - MucBP domain
MHLEJIOM_02090 4.55e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_02091 4.17e-204 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_02092 2.54e-211 - - - K - - - sequence-specific DNA binding
MHLEJIOM_02093 5.49e-261 yacL - - S - - - domain protein
MHLEJIOM_02094 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHLEJIOM_02095 4.85e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
MHLEJIOM_02096 1.22e-67 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
MHLEJIOM_02097 5.93e-93 - - - S - - - Protein of unknown function (DUF805)
MHLEJIOM_02098 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
MHLEJIOM_02099 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
MHLEJIOM_02100 5.42e-254 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
MHLEJIOM_02101 1.82e-277 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_02102 1.66e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_02103 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
MHLEJIOM_02104 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
MHLEJIOM_02105 7.26e-119 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
MHLEJIOM_02106 1.63e-156 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHLEJIOM_02107 3.87e-262 - - - S - - - Bacterial low temperature requirement A protein (LtrA)
MHLEJIOM_02108 5.25e-61 - - - - - - - -
MHLEJIOM_02109 9.49e-262 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MHLEJIOM_02110 1.59e-28 yhjA - - K - - - CsbD-like
MHLEJIOM_02112 1.5e-44 - - - - - - - -
MHLEJIOM_02113 5.02e-52 - - - - - - - -
MHLEJIOM_02114 8.53e-287 - - - EGP - - - Transmembrane secretion effector
MHLEJIOM_02115 1.34e-278 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHLEJIOM_02116 1.56e-190 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHLEJIOM_02118 2.57e-55 - - - - - - - -
MHLEJIOM_02119 5.64e-295 - - - S - - - Membrane
MHLEJIOM_02120 1.05e-187 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
MHLEJIOM_02121 0.0 - - - M - - - Cna protein B-type domain
MHLEJIOM_02122 2.03e-307 - - - - - - - -
MHLEJIOM_02123 0.0 - - - M - - - domain protein
MHLEJIOM_02124 7.69e-134 - - - - - - - -
MHLEJIOM_02125 1.54e-292 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
MHLEJIOM_02126 4.01e-262 - - - S - - - Protein of unknown function (DUF2974)
MHLEJIOM_02127 1.58e-99 - - - K - - - Helix-turn-helix XRE-family like proteins
MHLEJIOM_02128 2.05e-72 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
MHLEJIOM_02129 9.6e-81 - - - - - - - -
MHLEJIOM_02130 2.99e-176 - - - - - - - -
MHLEJIOM_02131 6.69e-61 - - - S - - - Enterocin A Immunity
MHLEJIOM_02132 2.5e-57 - - - S - - - Enterocin A Immunity
MHLEJIOM_02133 2.45e-59 spiA - - K - - - TRANSCRIPTIONal
MHLEJIOM_02134 0.0 - - - S - - - Putative threonine/serine exporter
MHLEJIOM_02136 6.92e-81 - - - - - - - -
MHLEJIOM_02137 1.88e-308 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
MHLEJIOM_02138 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MHLEJIOM_02140 3.45e-172 - 2.7.13.3 - T ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
MHLEJIOM_02141 7.99e-184 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHLEJIOM_02143 1.62e-12 - - - - - - - -
MHLEJIOM_02147 7.7e-161 - - - S - - - CAAX protease self-immunity
MHLEJIOM_02148 1.61e-74 - - - - - - - -
MHLEJIOM_02150 1.88e-69 - - - S - - - Enterocin A Immunity
MHLEJIOM_02151 3.2e-137 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHLEJIOM_02155 5.89e-231 ydhF - - S - - - Aldo keto reductase
MHLEJIOM_02156 1.43e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
MHLEJIOM_02157 6.61e-277 yqiG - - C - - - Oxidoreductase
MHLEJIOM_02158 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHLEJIOM_02159 2.2e-173 - - - - - - - -
MHLEJIOM_02160 6.42e-28 - - - - - - - -
MHLEJIOM_02161 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
MHLEJIOM_02162 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
MHLEJIOM_02163 9.77e-74 - - - - - - - -
MHLEJIOM_02164 2.97e-304 - - - EGP - - - Major Facilitator Superfamily
MHLEJIOM_02165 0.0 sufI - - Q - - - Multicopper oxidase
MHLEJIOM_02166 1.53e-35 - - - - - - - -
MHLEJIOM_02167 2.22e-144 - - - P - - - Cation efflux family
MHLEJIOM_02168 1.23e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
MHLEJIOM_02169 6.58e-226 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHLEJIOM_02170 5.89e-185 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
MHLEJIOM_02171 3.38e-170 - 3.6.3.35 - P ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
MHLEJIOM_02172 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
MHLEJIOM_02173 6.85e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHLEJIOM_02174 5.54e-214 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHLEJIOM_02175 2.83e-152 - - - GM - - - NmrA-like family
MHLEJIOM_02176 8.09e-146 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
MHLEJIOM_02177 2.74e-99 - - - - - - - -
MHLEJIOM_02178 0.0 - - - M - - - domain protein
MHLEJIOM_02179 2.09e-211 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
MHLEJIOM_02180 2.1e-27 - - - - - - - -
MHLEJIOM_02181 3.3e-102 - - - - - - - -
MHLEJIOM_02184 2.06e-67 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHLEJIOM_02185 1.58e-91 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHLEJIOM_02188 9.76e-79 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHLEJIOM_02189 3.22e-183 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHLEJIOM_02190 9.39e-284 - - - P - - - Cation transporter/ATPase, N-terminus
MHLEJIOM_02191 1.99e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
MHLEJIOM_02192 1.49e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHLEJIOM_02193 2.46e-174 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_02194 3.27e-187 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_02195 5.18e-224 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
MHLEJIOM_02196 0.0 - 6.2.1.48 - IQ ko:K02182 - ko00000,ko01000 AMP-binding enzyme C-terminal domain
MHLEJIOM_02197 3.03e-296 - - - I - - - Acyltransferase family
MHLEJIOM_02198 1.17e-154 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_02199 3.98e-190 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_02200 1.26e-171 XK27_06950 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_02201 1.22e-172 XK27_06945 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_02202 1.48e-102 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_02204 1.15e-79 - - - S - - - Protein of unknown function (DUF2785)
MHLEJIOM_02205 1.44e-142 - - - - - - - -
MHLEJIOM_02206 1.51e-73 - - - - - - - -
MHLEJIOM_02207 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
MHLEJIOM_02208 2.98e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHLEJIOM_02209 5.95e-140 - - - K - - - Bacterial regulatory proteins, tetR family
MHLEJIOM_02210 2.39e-234 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
MHLEJIOM_02211 7.4e-164 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
MHLEJIOM_02212 1.5e-44 - - - - - - - -
MHLEJIOM_02213 2.18e-169 tipA - - K - - - TipAS antibiotic-recognition domain
MHLEJIOM_02214 1.39e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHLEJIOM_02215 1.13e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHLEJIOM_02216 1.92e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHLEJIOM_02217 2.32e-197 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHLEJIOM_02218 6.72e-140 - - - - - - - -
MHLEJIOM_02219 5.46e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
MHLEJIOM_02220 1.26e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHLEJIOM_02221 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHLEJIOM_02222 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHLEJIOM_02223 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
MHLEJIOM_02224 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHLEJIOM_02225 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHLEJIOM_02226 2.01e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHLEJIOM_02227 4.07e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
MHLEJIOM_02228 2.6e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
MHLEJIOM_02229 5.74e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHLEJIOM_02230 1.62e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHLEJIOM_02231 2.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHLEJIOM_02232 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHLEJIOM_02233 8.67e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHLEJIOM_02234 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHLEJIOM_02235 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHLEJIOM_02236 5.93e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHLEJIOM_02237 3.55e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
MHLEJIOM_02238 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHLEJIOM_02239 6.88e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHLEJIOM_02240 5.25e-72 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHLEJIOM_02241 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHLEJIOM_02242 1.03e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHLEJIOM_02243 1.02e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHLEJIOM_02244 8.08e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
MHLEJIOM_02245 4.01e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHLEJIOM_02246 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
MHLEJIOM_02247 3.63e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
MHLEJIOM_02248 3.96e-137 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
MHLEJIOM_02249 8.34e-256 - - - K - - - WYL domain
MHLEJIOM_02250 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHLEJIOM_02251 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHLEJIOM_02252 1.11e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHLEJIOM_02253 0.0 - - - M - - - domain protein
MHLEJIOM_02254 1.81e-47 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
MHLEJIOM_02255 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHLEJIOM_02256 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHLEJIOM_02257 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHLEJIOM_02258 4.32e-105 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
MHLEJIOM_02259 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
MHLEJIOM_02260 8.82e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHLEJIOM_02261 8.47e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHLEJIOM_02262 2.94e-206 - - - S - - - WxL domain surface cell wall-binding
MHLEJIOM_02263 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHLEJIOM_02264 1.14e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
MHLEJIOM_02265 4.44e-309 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHLEJIOM_02266 1.17e-105 yabR - - J ko:K07571 - ko00000 RNA binding
MHLEJIOM_02267 3.35e-87 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
MHLEJIOM_02268 1.99e-53 yabO - - J - - - S4 domain protein
MHLEJIOM_02269 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
MHLEJIOM_02270 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHLEJIOM_02271 4.28e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHLEJIOM_02272 5.04e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
MHLEJIOM_02273 0.0 - - - S - - - Putative peptidoglycan binding domain
MHLEJIOM_02274 1.34e-154 - - - S - - - (CBS) domain
MHLEJIOM_02275 1.19e-168 yciB - - M - - - ErfK YbiS YcfS YnhG
MHLEJIOM_02276 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MHLEJIOM_02277 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
MHLEJIOM_02278 1.63e-111 queT - - S - - - QueT transporter
MHLEJIOM_02279 5.68e-83 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
MHLEJIOM_02280 4.66e-44 - - - - - - - -
MHLEJIOM_02281 1.05e-273 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHLEJIOM_02282 2.63e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHLEJIOM_02283 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHLEJIOM_02285 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHLEJIOM_02286 4.87e-187 - - - - - - - -
MHLEJIOM_02287 3.44e-08 - - - - - - - -
MHLEJIOM_02288 4.35e-159 - - - S - - - Tetratricopeptide repeat
MHLEJIOM_02289 2.61e-163 - - - - - - - -
MHLEJIOM_02290 2.29e-87 - - - - - - - -
MHLEJIOM_02291 2.28e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
MHLEJIOM_02292 9.48e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHLEJIOM_02293 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHLEJIOM_02294 3.42e-202 ybbB - - S - - - Protein of unknown function (DUF1211)
MHLEJIOM_02295 1.15e-111 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHLEJIOM_02296 3.48e-103 ywiB - - S - - - Domain of unknown function (DUF1934)
MHLEJIOM_02297 2.32e-199 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
MHLEJIOM_02298 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
MHLEJIOM_02299 1.41e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MHLEJIOM_02300 2.5e-236 - - - S - - - DUF218 domain
MHLEJIOM_02301 1.31e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHLEJIOM_02302 1.06e-262 - - - Q - - - Imidazolonepropionase and related amidohydrolases
MHLEJIOM_02303 9.41e-297 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MHLEJIOM_02304 1.88e-244 - - - E - - - glutamate:sodium symporter activity
MHLEJIOM_02305 1.54e-73 nudA - - S - - - ASCH
MHLEJIOM_02306 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHLEJIOM_02307 2.7e-298 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHLEJIOM_02308 5.97e-285 ysaA - - V - - - RDD family
MHLEJIOM_02309 1.01e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
MHLEJIOM_02310 6.15e-153 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_02311 5.89e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
MHLEJIOM_02312 1.99e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
MHLEJIOM_02313 6.63e-232 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHLEJIOM_02314 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
MHLEJIOM_02315 2.04e-202 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHLEJIOM_02316 3.92e-129 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHLEJIOM_02317 9.1e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
MHLEJIOM_02318 2.57e-104 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
MHLEJIOM_02319 1.35e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
MHLEJIOM_02320 4.09e-219 yqhA - - G - - - Aldose 1-epimerase
MHLEJIOM_02321 1.43e-160 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
MHLEJIOM_02322 1.5e-201 - - - T - - - GHKL domain
MHLEJIOM_02323 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHLEJIOM_02324 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
MHLEJIOM_02325 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHLEJIOM_02326 4.11e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
MHLEJIOM_02327 1.46e-196 yunF - - F - - - Protein of unknown function DUF72
MHLEJIOM_02328 1.09e-118 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
MHLEJIOM_02329 3.11e-218 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
MHLEJIOM_02330 9.14e-139 yiiE - - S - - - Protein of unknown function (DUF1211)
MHLEJIOM_02331 3.28e-164 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
MHLEJIOM_02332 6.41e-24 - - - - - - - -
MHLEJIOM_02333 1.83e-183 - - - - - - - -
MHLEJIOM_02335 5.33e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
MHLEJIOM_02336 4.7e-50 - - - - - - - -
MHLEJIOM_02337 3.25e-203 ypuA - - S - - - Protein of unknown function (DUF1002)
MHLEJIOM_02338 2.57e-223 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHLEJIOM_02339 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MHLEJIOM_02340 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
MHLEJIOM_02341 2.04e-223 ydhF - - S - - - Aldo keto reductase
MHLEJIOM_02342 2.42e-197 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MHLEJIOM_02343 2.27e-119 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
MHLEJIOM_02344 4.58e-305 dinF - - V - - - MatE
MHLEJIOM_02345 7.19e-157 - - - S ko:K06872 - ko00000 TPM domain
MHLEJIOM_02346 1.15e-132 lemA - - S ko:K03744 - ko00000 LemA family
MHLEJIOM_02347 1.48e-246 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
MHLEJIOM_02348 1.75e-115 choS - - EM ko:K05845,ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHLEJIOM_02350 0.0 - - - L - - - DNA helicase
MHLEJIOM_02351 9.39e-192 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
MHLEJIOM_02352 3.77e-221 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
MHLEJIOM_02353 1.15e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
MHLEJIOM_02355 3.47e-147 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
MHLEJIOM_02356 6.41e-92 - - - K - - - MarR family
MHLEJIOM_02357 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
MHLEJIOM_02358 6.25e-246 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
MHLEJIOM_02359 2.79e-185 - - - S - - - hydrolase
MHLEJIOM_02360 4.04e-79 - - - - - - - -
MHLEJIOM_02361 1.99e-16 - - - - - - - -
MHLEJIOM_02362 3.29e-136 - - - S - - - Protein of unknown function (DUF1275)
MHLEJIOM_02363 1.56e-161 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
MHLEJIOM_02364 7.22e-197 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
MHLEJIOM_02365 3.81e-115 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHLEJIOM_02366 4.39e-213 - - - K - - - LysR substrate binding domain
MHLEJIOM_02367 4.96e-290 - - - EK - - - Aminotransferase, class I
MHLEJIOM_02368 1.97e-235 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHLEJIOM_02369 4.42e-154 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
MHLEJIOM_02370 4.31e-115 - - - - - - - -
MHLEJIOM_02371 0.0 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_02372 5.18e-221 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
MHLEJIOM_02373 3.35e-167 rpl - - K - - - Helix-turn-helix domain, rpiR family
MHLEJIOM_02374 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHLEJIOM_02375 5.44e-175 - - - K - - - UTRA domain
MHLEJIOM_02376 0.0 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MHLEJIOM_02377 2.34e-214 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02378 9.8e-169 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_02379 2.84e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_02380 3.62e-62 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
MHLEJIOM_02381 1e-63 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_02382 0.0 bgl 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
MHLEJIOM_02383 3.67e-196 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
MHLEJIOM_02384 1.33e-312 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
MHLEJIOM_02385 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
MHLEJIOM_02386 1.48e-305 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_02387 1.1e-172 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
MHLEJIOM_02388 1.51e-175 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
MHLEJIOM_02390 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHLEJIOM_02391 1.25e-67 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_02392 1.49e-107 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_02393 2.3e-186 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
MHLEJIOM_02394 3.2e-206 - - - J - - - Methyltransferase domain
MHLEJIOM_02395 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
MHLEJIOM_02398 0.0 - - - M - - - Right handed beta helix region
MHLEJIOM_02399 0.0 - - - M - - - Heparinase II/III N-terminus
MHLEJIOM_02401 1.14e-105 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
MHLEJIOM_02402 8.63e-185 agaD - - G ko:K02747 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_02403 6.84e-186 - - - G ko:K02746 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_02404 1.72e-114 - - - G ko:K02745 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02405 2.11e-296 ugl 3.2.1.180 GH88 S ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
MHLEJIOM_02406 8.79e-201 - - - S - - - Psort location Cytoplasmic, score
MHLEJIOM_02407 1.1e-179 - - - K - - - Bacterial transcriptional regulator
MHLEJIOM_02408 2.17e-208 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MHLEJIOM_02409 6.38e-193 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MHLEJIOM_02410 2.71e-152 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
MHLEJIOM_02411 8.25e-249 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
MHLEJIOM_02412 1.19e-149 alkD - - L - - - DNA alkylation repair enzyme
MHLEJIOM_02413 4.14e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHLEJIOM_02414 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHLEJIOM_02415 1.43e-220 ykoT - - M - - - Glycosyl transferase family 2
MHLEJIOM_02416 3.67e-153 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
MHLEJIOM_02417 2.69e-148 - - - S ko:K03975 - ko00000 SNARE-like domain protein
MHLEJIOM_02418 3.27e-311 kinE - - T - - - Histidine kinase
MHLEJIOM_02419 2.3e-161 llrE - - K - - - Transcriptional regulatory protein, C terminal
MHLEJIOM_02420 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
MHLEJIOM_02421 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
MHLEJIOM_02422 0.0 hylB 4.2.2.1 PL8 N ko:K01727 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
MHLEJIOM_02424 0.0 - - - - - - - -
MHLEJIOM_02426 8.04e-140 - - - - - - - -
MHLEJIOM_02427 2.51e-109 - - - - - - - -
MHLEJIOM_02428 1.49e-108 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHLEJIOM_02429 3.81e-255 - - - S - - - DUF218 domain
MHLEJIOM_02430 1.57e-184 - - - P - - - Sulfatase
MHLEJIOM_02431 4.08e-27 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02432 5.16e-54 - 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02433 5.73e-60 - - - K ko:K03710,ko:K11922 - ko00000,ko03000 Protein of unknown function (DUF_B2219)
MHLEJIOM_02434 4.82e-140 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_02435 2.22e-126 - - - G - - - PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_02436 3.47e-219 - - - Q - - - PHP domain protein
MHLEJIOM_02437 4.16e-103 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
MHLEJIOM_02438 2.84e-173 ydeM3 - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
MHLEJIOM_02439 5.81e-123 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
MHLEJIOM_02440 1.61e-176 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
MHLEJIOM_02441 3.56e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
MHLEJIOM_02442 2.58e-276 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
MHLEJIOM_02443 3.79e-155 - - - S - - - Domain of unknown function (DUF4310)
MHLEJIOM_02444 6.8e-176 - - - S - - - Domain of unknown function (DUF4311)
MHLEJIOM_02445 1.51e-74 - - - S - - - Domain of unknown function (DUF4312)
MHLEJIOM_02446 5.01e-80 - - - S - - - Glycine-rich SFCGS
MHLEJIOM_02447 1.01e-71 - - - S - - - PRD domain
MHLEJIOM_02448 0.0 - - - K - - - Mga helix-turn-helix domain
MHLEJIOM_02450 3.11e-32 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
MHLEJIOM_02452 1.68e-59 XK27_06950 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
MHLEJIOM_02453 8.74e-161 - - - H - - - Pfam:Transaldolase
MHLEJIOM_02454 2.82e-78 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
MHLEJIOM_02455 3.01e-254 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
MHLEJIOM_02456 5.81e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
MHLEJIOM_02457 2.63e-115 srlM1 - - K - - - Glucitol operon activator protein (GutM)
MHLEJIOM_02458 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
MHLEJIOM_02459 4.13e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
MHLEJIOM_02460 1.57e-177 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MHLEJIOM_02461 1.45e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
MHLEJIOM_02462 1.21e-209 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
MHLEJIOM_02463 8.64e-178 - - - K - - - DeoR C terminal sensor domain
MHLEJIOM_02464 5.26e-148 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
MHLEJIOM_02465 3.36e-61 sgaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_02466 0.0 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHLEJIOM_02467 4.89e-105 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHLEJIOM_02468 4.59e-275 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
MHLEJIOM_02469 2.27e-161 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MHLEJIOM_02470 3.65e-139 - - - E - - - Alcohol dehydrogenase GroES-like domain
MHLEJIOM_02471 9.8e-232 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHLEJIOM_02472 3.48e-36 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PFAM phosphotransferase system lactose cellobiose-specific IIB subunit
MHLEJIOM_02473 2.53e-29 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS IIA-like nitrogen-regulatory protein PtsN
MHLEJIOM_02474 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
MHLEJIOM_02475 1.68e-47 - - - K ko:K02444 - ko00000,ko03000 DeoR C terminal sensor domain
MHLEJIOM_02476 3.48e-36 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PFAM phosphotransferase system lactose cellobiose-specific IIB subunit
MHLEJIOM_02477 1.28e-200 - - - GK - - - ROK family
MHLEJIOM_02478 1.83e-231 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
MHLEJIOM_02479 0.0 - - - E - - - Peptidase family M20/M25/M40
MHLEJIOM_02480 3.68e-170 - - - K ko:K03710 - ko00000,ko03000 UTRA
MHLEJIOM_02481 0.0 - 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
MHLEJIOM_02482 4.79e-272 - - - EGP - - - Transporter, major facilitator family protein
MHLEJIOM_02483 1.4e-263 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
MHLEJIOM_02484 2.27e-114 - - - M ko:K03828 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHLEJIOM_02485 6.18e-132 laaE - - K - - - Transcriptional regulator PadR-like family
MHLEJIOM_02486 0.0 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
MHLEJIOM_02487 7.27e-112 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_02488 1.17e-117 yveA - - Q - - - Isochorismatase family
MHLEJIOM_02489 2.96e-59 - - - S - - - Zeta toxin
MHLEJIOM_02490 6.83e-164 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHLEJIOM_02491 1.13e-133 - - - IQ - - - KR domain
MHLEJIOM_02492 3.71e-84 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02493 4.09e-46 - - - G - - - PTS system fructose IIA component
MHLEJIOM_02494 3.26e-311 - - - G - - - PTS system sorbose-specific iic component
MHLEJIOM_02495 8.14e-194 - - - E - - - Alcohol dehydrogenase GroES-like domain
MHLEJIOM_02496 7.91e-104 - - - K - - - Helix-turn-helix domain, rpiR family
MHLEJIOM_02497 1.06e-46 - - - - - - - -
MHLEJIOM_02498 2.25e-74 ps105 - - - - - - -
MHLEJIOM_02500 1.09e-124 - - - K - - - Helix-turn-helix domain
MHLEJIOM_02501 3.79e-155 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
MHLEJIOM_02502 2.63e-91 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHLEJIOM_02503 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHLEJIOM_02504 5.9e-192 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_02505 1.3e-210 - - - P ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type sugar transport systems, permease components
MHLEJIOM_02506 2.99e-270 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_02507 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHLEJIOM_02508 1.89e-139 pncA - - Q - - - Isochorismatase family
MHLEJIOM_02509 3.28e-175 - - - F - - - NUDIX domain
MHLEJIOM_02510 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
MHLEJIOM_02511 1.19e-186 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
MHLEJIOM_02512 3.21e-245 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
MHLEJIOM_02513 1.22e-246 - - - V - - - Beta-lactamase
MHLEJIOM_02514 1.95e-195 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHLEJIOM_02515 3.72e-210 - - - K - - - Helix-turn-helix domain, rpiR family
MHLEJIOM_02516 1.67e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02517 1.56e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
MHLEJIOM_02518 8.76e-177 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
MHLEJIOM_02519 4.32e-259 - - - S - - - endonuclease exonuclease phosphatase family protein
MHLEJIOM_02520 3.1e-218 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
MHLEJIOM_02521 1.08e-172 draG - - O - - - ADP-ribosylglycohydrolase
MHLEJIOM_02522 8.82e-68 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
MHLEJIOM_02523 2.59e-172 - - - S - - - -acetyltransferase
MHLEJIOM_02524 3.92e-120 yfbM - - K - - - FR47-like protein
MHLEJIOM_02525 5.71e-121 - - - E - - - HAD-hyrolase-like
MHLEJIOM_02526 5.91e-236 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
MHLEJIOM_02527 2.33e-120 - - - K - - - Acetyltransferase (GNAT) domain
MHLEJIOM_02528 6.44e-107 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHLEJIOM_02529 4.68e-99 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
MHLEJIOM_02530 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHLEJIOM_02531 6.32e-253 ysdE - - P - - - Citrate transporter
MHLEJIOM_02532 5.71e-89 - - - - - - - -
MHLEJIOM_02533 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
MHLEJIOM_02534 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
MHLEJIOM_02535 2.4e-133 - - - - - - - -
MHLEJIOM_02536 0.0 cadA - - P - - - P-type ATPase
MHLEJIOM_02537 1.8e-99 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
MHLEJIOM_02538 2.35e-92 - - - S - - - Iron-sulphur cluster biosynthesis
MHLEJIOM_02539 6.92e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
MHLEJIOM_02540 4.32e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
MHLEJIOM_02541 1.05e-182 yycI - - S - - - YycH protein
MHLEJIOM_02542 0.0 yycH - - S - - - YycH protein
MHLEJIOM_02543 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
MHLEJIOM_02544 3.03e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
MHLEJIOM_02545 4.31e-157 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
MHLEJIOM_02546 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
MHLEJIOM_02547 1.39e-299 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHLEJIOM_02548 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
MHLEJIOM_02549 8.87e-269 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
MHLEJIOM_02550 9.09e-97 - - - S - - - Domain of unknown function (DUF3284)
MHLEJIOM_02551 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_02552 2.8e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
MHLEJIOM_02553 4.13e-68 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_02554 8.36e-72 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
MHLEJIOM_02555 6.11e-139 yokL3 - - J - - - Acetyltransferase (GNAT) domain
MHLEJIOM_02556 1.84e-110 - - - F - - - NUDIX domain
MHLEJIOM_02557 8.74e-116 - - - S - - - AAA domain
MHLEJIOM_02558 1.35e-147 ycaC - - Q - - - Isochorismatase family
MHLEJIOM_02559 0.0 - - - EGP - - - Major Facilitator Superfamily
MHLEJIOM_02560 2.67e-272 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
MHLEJIOM_02561 1.22e-219 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
MHLEJIOM_02562 1.08e-84 manO - - S - - - Domain of unknown function (DUF956)
MHLEJIOM_02563 1.73e-216 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
MHLEJIOM_02564 1.57e-171 manM - - G ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
MHLEJIOM_02565 1.44e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
MHLEJIOM_02566 1.09e-275 - - - EGP - - - Major facilitator Superfamily
MHLEJIOM_02567 9.91e-241 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MHLEJIOM_02568 2.29e-190 - - - K - - - Helix-turn-helix XRE-family like proteins
MHLEJIOM_02569 6.17e-204 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
MHLEJIOM_02571 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_02572 3.81e-172 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_02573 6.41e-41 - - - - - - - -
MHLEJIOM_02574 2.85e-303 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHLEJIOM_02575 5.43e-166 - - - S - - - Protein of unknown function (DUF975)
MHLEJIOM_02576 5.96e-53 - - - S - - - Iron-sulphur cluster biosynthesis
MHLEJIOM_02577 8.12e-69 - - - - - - - -
MHLEJIOM_02578 1.75e-105 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
MHLEJIOM_02579 3.07e-181 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
MHLEJIOM_02580 7.76e-186 - - - S - - - AAA ATPase domain
MHLEJIOM_02581 3.22e-214 - - - G - - - Phosphotransferase enzyme family
MHLEJIOM_02582 1.09e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_02583 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_02584 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
MHLEJIOM_02585 2.69e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
MHLEJIOM_02586 9.04e-137 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
MHLEJIOM_02587 3.67e-182 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
MHLEJIOM_02588 1.24e-234 - - - S - - - Protein of unknown function DUF58
MHLEJIOM_02589 0.0 yebA - - E - - - Transglutaminase/protease-like homologues
MHLEJIOM_02590 2.46e-272 - - - M - - - Glycosyl transferases group 1
MHLEJIOM_02591 1.34e-126 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
MHLEJIOM_02592 1.23e-185 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
MHLEJIOM_02593 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
MHLEJIOM_02594 1e-147 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
MHLEJIOM_02595 5.19e-62 yjdF3 - - S - - - Protein of unknown function (DUF2992)
MHLEJIOM_02596 8.58e-271 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
MHLEJIOM_02597 5.39e-292 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
MHLEJIOM_02598 1.83e-76 - - - - - - - -
MHLEJIOM_02599 5.46e-269 yagE - - E - - - Amino acid permease
MHLEJIOM_02600 1.42e-218 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MHLEJIOM_02602 1.87e-217 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHLEJIOM_02603 2.32e-233 - - - D ko:K06889 - ko00000 Alpha beta
MHLEJIOM_02604 3.06e-238 lipA - - I - - - Carboxylesterase family
MHLEJIOM_02605 1.68e-275 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
MHLEJIOM_02606 9.2e-101 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHLEJIOM_02607 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
MHLEJIOM_02608 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
MHLEJIOM_02609 2.91e-168 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHLEJIOM_02610 2.23e-191 - - - S - - - haloacid dehalogenase-like hydrolase
MHLEJIOM_02611 5.93e-59 - - - - - - - -
MHLEJIOM_02612 6.72e-19 - - - - - - - -
MHLEJIOM_02613 1.51e-238 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MHLEJIOM_02614 1.68e-159 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_02615 2.42e-263 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
MHLEJIOM_02616 0.0 - - - M - - - Leucine rich repeats (6 copies)
MHLEJIOM_02617 9.41e-257 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
MHLEJIOM_02618 5.35e-289 amd - - E - - - Peptidase family M20/M25/M40
MHLEJIOM_02619 2.1e-104 - - - S - - - Threonine/Serine exporter, ThrE
MHLEJIOM_02620 5.4e-175 labL - - S - - - Putative threonine/serine exporter
MHLEJIOM_02622 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHLEJIOM_02623 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHLEJIOM_02624 1.42e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
MHLEJIOM_02625 4.53e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHLEJIOM_02626 2.99e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHLEJIOM_02627 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
MHLEJIOM_02628 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHLEJIOM_02629 1.02e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHLEJIOM_02631 4.07e-43 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
MHLEJIOM_02632 9.09e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHLEJIOM_02633 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHLEJIOM_02634 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHLEJIOM_02635 5.22e-163 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MHLEJIOM_02636 5.2e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHLEJIOM_02637 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
MHLEJIOM_02638 4.42e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHLEJIOM_02639 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHLEJIOM_02640 2.39e-98 - - - L - - - Initiator Replication protein
MHLEJIOM_02641 2.46e-38 - - - - - - - -
MHLEJIOM_02644 2.87e-60 - - - L - - - Protein involved in initiation of plasmid replication
MHLEJIOM_02645 1.02e-09 - - - - - - - -
MHLEJIOM_02646 4.82e-08 yokH - - G - - - SMI1 / KNR4 family
MHLEJIOM_02647 2.44e-17 - - - - - - - -
MHLEJIOM_02648 8.68e-24 - - - - - - - -
MHLEJIOM_02650 5.76e-25 - - - - - - - -
MHLEJIOM_02651 1.4e-46 chpA - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHLEJIOM_02652 2.81e-149 - - - L - - - Resolvase, N terminal domain
MHLEJIOM_02653 1.29e-59 - - - L - - - BRCA1 C Terminus (BRCT) domain
MHLEJIOM_02654 7.4e-110 - - - - - - - -
MHLEJIOM_02655 5.37e-88 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MHLEJIOM_02656 3.2e-203 - - - K - - - Sugar-specific transcriptional regulator TrmB
MHLEJIOM_02657 9.64e-191 - - - S - - - Sulfite exporter TauE/SafE
MHLEJIOM_02658 8.32e-229 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
MHLEJIOM_02659 1.91e-191 - 3.1.1.24 - S ko:K01055 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Alpha/beta hydrolase family
MHLEJIOM_02661 1.56e-200 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
MHLEJIOM_02662 3.34e-101 - - - - - - - -
MHLEJIOM_02664 6.45e-95 - - - - - - - -
MHLEJIOM_02665 4.95e-23 - - - - - - - -
MHLEJIOM_02666 2.05e-86 - - - - - - - -
MHLEJIOM_02667 3.27e-198 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
MHLEJIOM_02668 8.99e-157 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
MHLEJIOM_02669 2.21e-194 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
MHLEJIOM_02670 5.12e-122 M1-431 - - S - - - Protein of unknown function (DUF1706)
MHLEJIOM_02674 3.36e-24 - - - L - - - Psort location Cytoplasmic, score 8.87
MHLEJIOM_02677 3.4e-50 - - - L ko:K07483 - ko00000 Transposase and inactivated derivatives
MHLEJIOM_02678 2.04e-30 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHLEJIOM_02679 9.29e-23 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHLEJIOM_02680 1.19e-173 yvdE - - K - - - helix_turn _helix lactose operon repressor
MHLEJIOM_02681 3.22e-171 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
MHLEJIOM_02682 3.31e-257 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_02683 7.62e-221 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
MHLEJIOM_02684 5.05e-286 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
MHLEJIOM_02685 3.92e-220 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
MHLEJIOM_02686 3.08e-92 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
MHLEJIOM_02687 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
MHLEJIOM_02688 1.07e-306 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
MHLEJIOM_02689 2.14e-284 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
MHLEJIOM_02691 5.24e-115 - - - D - - - AAA domain
MHLEJIOM_02692 6.62e-89 - - - K - - - Primase C terminal 1 (PriCT-1)
MHLEJIOM_02693 5.08e-34 - - - L - - - Transposase DDE domain
MHLEJIOM_02694 4.92e-81 opuCD - - U ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
MHLEJIOM_02695 9.11e-208 - - - P - - - YhfZ C-terminal domain
MHLEJIOM_02697 1.96e-73 - - - S - - - Protein of unknown function DUF2620
MHLEJIOM_02698 1.66e-274 - - - S - - - Protein of unknown function
MHLEJIOM_02699 1.44e-199 php - - S ko:K07048 - ko00000 Phosphotriesterase family
MHLEJIOM_02700 5.73e-231 - - - E - - - Cys/Met metabolism PLP-dependent enzyme
MHLEJIOM_02701 1.33e-257 - - - E - - - Alanine racemase, N-terminal domain
MHLEJIOM_02702 6.59e-295 - - - G - - - Metalloenzyme superfamily
MHLEJIOM_02703 4.49e-77 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
MHLEJIOM_02706 3.19e-120 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
MHLEJIOM_02708 1.92e-76 tnpR1 - - L - - - Resolvase, N terminal domain
MHLEJIOM_02709 5.38e-40 - - - L ko:K07484 - ko00000 Transposase IS66 family
MHLEJIOM_02710 6.37e-82 - - - L ko:K07484 - ko00000 IS66 Orf2 like protein
MHLEJIOM_02711 2.58e-37 - - - - - - - -
MHLEJIOM_02712 2.78e-86 - - - S - - - Uncharacterised protein family UPF0047
MHLEJIOM_02713 3.7e-96 - 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Triose-phosphate isomerase
MHLEJIOM_02714 4.32e-123 gatY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
MHLEJIOM_02715 1.57e-39 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, galactitol-specific IIB component
MHLEJIOM_02716 1.82e-204 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
MHLEJIOM_02717 9.36e-34 - 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHLEJIOM_02719 5.28e-97 - - - K ko:K02538 - ko00000,ko03000 PRD domain
MHLEJIOM_02720 2.19e-28 - - - - - - - -
MHLEJIOM_02722 1.09e-216 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
MHLEJIOM_02723 7.42e-30 - - - - - - - -
MHLEJIOM_02724 1.4e-26 - - - S - - - Family of unknown function (DUF5388)
MHLEJIOM_02725 4.04e-138 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
MHLEJIOM_02726 2.36e-98 - - - S - - - Replication initiator protein A (RepA) N-terminus
MHLEJIOM_02727 8.78e-119 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
MHLEJIOM_02728 1.48e-180 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
MHLEJIOM_02729 1.2e-281 B4168_4126 - - L ko:K07493 - ko00000 Transposase
MHLEJIOM_02730 1.28e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
MHLEJIOM_02731 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
MHLEJIOM_02732 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
MHLEJIOM_02733 2.76e-86 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
MHLEJIOM_02734 0.000722 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase, C-terminal sheet domain
MHLEJIOM_02736 1.73e-226 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
MHLEJIOM_02737 6.15e-234 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHLEJIOM_02739 5.93e-12 - - - - - - - -
MHLEJIOM_02740 2.37e-91 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
MHLEJIOM_02742 4.07e-43 - - - - - - - -
MHLEJIOM_02743 6.76e-83 - - - - - - - -
MHLEJIOM_02744 1.79e-137 - - - L - - - Integrase
MHLEJIOM_02745 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
MHLEJIOM_02746 1.46e-164 mga - - K ko:K02538 - ko00000,ko03000 transcriptional antiterminator
MHLEJIOM_02747 3.84e-154 - - - K - - - Helix-turn-helix domain, rpiR family
MHLEJIOM_02748 6.91e-156 - - - S - - - Plasmid replication protein
MHLEJIOM_02749 4.7e-25 - - - L - - - Resolvase, N terminal domain
MHLEJIOM_02750 1.45e-46 - - - - - - - -
MHLEJIOM_02751 4.03e-303 - - - L ko:K07485 - ko00000 Transposase
MHLEJIOM_02752 8.94e-48 - - - L - - - Transposase
MHLEJIOM_02753 1.06e-107 is18 - - L - - - COG2801 Transposase and inactivated derivatives
MHLEJIOM_02754 4.94e-245 - - - L - - - Transposase and inactivated derivatives, IS30 family
MHLEJIOM_02755 2.27e-247 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
MHLEJIOM_02756 2.92e-54 - 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 - Q ko:K10027 ko00906,ko01100,ko01110,map00906,map01100,map01110 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
MHLEJIOM_02757 3.35e-247 - - - L ko:K07482 - ko00000 Helix-turn-helix domain
MHLEJIOM_02758 5e-118 ydhK - - M - - - Protein of unknown function (DUF1541)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)