ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HKNFCEOD_00001 4.4e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HKNFCEOD_00002 4.45e-253 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HKNFCEOD_00003 4.17e-20 - - - - - - - -
HKNFCEOD_00005 3.04e-258 - - - M - - - Glycosyltransferase like family 2
HKNFCEOD_00006 1.16e-204 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HKNFCEOD_00007 1.24e-103 fld - - C ko:K03839 - ko00000 Flavodoxin
HKNFCEOD_00008 9.73e-230 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HKNFCEOD_00009 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HKNFCEOD_00011 2.96e-144 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_00012 1.41e-306 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
HKNFCEOD_00013 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HKNFCEOD_00014 4.16e-07 - - - - - - - -
HKNFCEOD_00016 4.49e-93 - - - S - - - Domain of unknown function (DUF3284)
HKNFCEOD_00017 7.9e-74 chbA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HKNFCEOD_00018 4.41e-289 yfmL - - L - - - DEAD DEAH box helicase
HKNFCEOD_00019 2.21e-226 mocA - - S - - - Oxidoreductase
HKNFCEOD_00020 1.9e-79 - - - S - - - Domain of unknown function (DUF4828)
HKNFCEOD_00021 9.39e-80 - - - S - - - Protein of unknown function (DUF1093)
HKNFCEOD_00022 1.98e-177 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HKNFCEOD_00023 1.24e-39 - - - - - - - -
HKNFCEOD_00024 1.37e-165 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HKNFCEOD_00025 2.87e-213 yitS - - S - - - Uncharacterised protein, DegV family COG1307
HKNFCEOD_00026 3.04e-84 - - - K - - - Acetyltransferase (GNAT) family
HKNFCEOD_00027 0.0 - - - EGP - - - Major Facilitator
HKNFCEOD_00028 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HKNFCEOD_00029 2.44e-210 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HKNFCEOD_00030 5.1e-190 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKNFCEOD_00031 9.24e-281 yttB - - EGP - - - Major Facilitator
HKNFCEOD_00032 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKNFCEOD_00033 4.97e-248 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HKNFCEOD_00034 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNFCEOD_00035 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKNFCEOD_00036 3.61e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKNFCEOD_00037 4.26e-271 camS - - S - - - sex pheromone
HKNFCEOD_00038 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKNFCEOD_00039 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HKNFCEOD_00041 5.65e-46 - - - S - - - Bacterial protein of unknown function (DUF898)
HKNFCEOD_00042 3.51e-180 - 3.1.1.5 - E ko:K10804 ko01040,map01040 ko00000,ko00001,ko01000,ko01004 GDSL-like Lipase/Acylhydrolase
HKNFCEOD_00043 3.59e-266 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HKNFCEOD_00045 0.0 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Belongs to the DNA polymerase type-Y family
HKNFCEOD_00046 8.56e-74 - - - - - - - -
HKNFCEOD_00047 1.53e-88 - - - - - - - -
HKNFCEOD_00048 7.36e-94 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HKNFCEOD_00049 5.2e-20 - - - - - - - -
HKNFCEOD_00050 1.34e-96 - - - S - - - acetyltransferase
HKNFCEOD_00051 0.0 yclK - - T - - - Histidine kinase
HKNFCEOD_00052 3.55e-174 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HKNFCEOD_00053 5.39e-92 - - - S - - - SdpI/YhfL protein family
HKNFCEOD_00056 0.0 rafA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKNFCEOD_00057 2.65e-213 arbZ - - I - - - Phosphate acyltransferases
HKNFCEOD_00058 1.83e-230 arbY - - M - - - family 8
HKNFCEOD_00059 8.22e-212 arbx - - M - - - Glycosyl transferase family 8
HKNFCEOD_00060 7.51e-191 arbV - - I - - - Phosphate acyltransferases
HKNFCEOD_00061 0.0 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HKNFCEOD_00062 8.54e-81 - - - - - - - -
HKNFCEOD_00063 3.73e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HKNFCEOD_00065 1.42e-24 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HKNFCEOD_00066 3.32e-32 - - - - - - - -
HKNFCEOD_00068 1e-35 - - - - ko:K02245 - ko00000,ko00002,ko02044 -
HKNFCEOD_00069 3.76e-217 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HKNFCEOD_00070 1.02e-196 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HKNFCEOD_00071 5.85e-169 yebC - - K - - - Transcriptional regulatory protein
HKNFCEOD_00072 2.75e-105 - - - S - - - VanZ like family
HKNFCEOD_00073 0.0 pepF2 - - E - - - Oligopeptidase F
HKNFCEOD_00075 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKNFCEOD_00076 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKNFCEOD_00077 2.25e-216 ybbR - - S - - - YbbR-like protein
HKNFCEOD_00078 3.82e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKNFCEOD_00079 4.45e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKNFCEOD_00080 9.96e-236 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_00081 1.05e-143 - - - K - - - Transcriptional regulator
HKNFCEOD_00082 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
HKNFCEOD_00084 8.49e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_00085 6.79e-186 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00086 1.44e-189 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00087 9.1e-263 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKNFCEOD_00088 1.97e-124 - - - K - - - Cupin domain
HKNFCEOD_00089 0.0 yvgP - - P ko:K03316 - ko00000 Sodium proton antiporter
HKNFCEOD_00090 3.2e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HKNFCEOD_00091 8.14e-194 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HKNFCEOD_00092 4.66e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HKNFCEOD_00093 2.34e-271 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_00094 1.41e-208 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00096 3.18e-106 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HKNFCEOD_00097 8.65e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HKNFCEOD_00098 5.91e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKNFCEOD_00099 4e-203 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKNFCEOD_00100 7.57e-119 - - - - - - - -
HKNFCEOD_00101 3.63e-136 - - - K ko:K06977 - ko00000 Acetyltransferase (GNAT) domain
HKNFCEOD_00102 3.08e-248 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_00103 7.01e-213 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
HKNFCEOD_00104 1.1e-188 malF - - G ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_00105 2.48e-311 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKNFCEOD_00106 1.03e-305 YSH1 - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Metallo-beta-lactamase superfamily
HKNFCEOD_00107 1.13e-32 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HKNFCEOD_00108 2.33e-23 - - - - - - - -
HKNFCEOD_00109 3.01e-16 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_00110 3.7e-21 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_00111 6.75e-153 - 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HKNFCEOD_00112 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HKNFCEOD_00113 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HKNFCEOD_00114 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HKNFCEOD_00115 2.21e-226 yvdE - - K - - - helix_turn _helix lactose operon repressor
HKNFCEOD_00116 4.47e-108 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKNFCEOD_00117 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKNFCEOD_00118 4.01e-181 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HKNFCEOD_00119 5.04e-43 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HKNFCEOD_00120 0.0 eriC - - P ko:K03281 - ko00000 chloride
HKNFCEOD_00121 8.99e-62 - - - - - - - -
HKNFCEOD_00122 5.21e-293 mdt(A) - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HKNFCEOD_00123 2.05e-313 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNFCEOD_00124 2.81e-180 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKNFCEOD_00125 2.16e-282 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HKNFCEOD_00126 2.1e-247 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKNFCEOD_00127 5.52e-241 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HKNFCEOD_00130 5.97e-132 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKNFCEOD_00131 3.19e-105 ohrR - - K ko:K18906 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HKNFCEOD_00132 9.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HKNFCEOD_00133 2.99e-248 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HKNFCEOD_00134 8.53e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HKNFCEOD_00135 3.63e-111 - - - S - - - Short repeat of unknown function (DUF308)
HKNFCEOD_00136 2.72e-78 - - - S - - - Protein of unknown function (DUF3021)
HKNFCEOD_00137 1.2e-95 - - - K - - - LytTr DNA-binding domain
HKNFCEOD_00138 2.56e-190 - - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HKNFCEOD_00139 1.3e-208 - - - V ko:K01990,ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_00140 8.38e-186 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKNFCEOD_00141 1.57e-158 cah 4.2.1.1 - P ko:K01674 ko00910,map00910 ko00000,ko00001,ko01000 Eukaryotic-type carbonic anhydrase
HKNFCEOD_00142 1.06e-69 ybjQ - - S - - - Belongs to the UPF0145 family
HKNFCEOD_00143 2.05e-203 - - - C - - - nadph quinone reductase
HKNFCEOD_00144 4.75e-316 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HKNFCEOD_00145 2.3e-226 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HKNFCEOD_00146 1.23e-153 yqgG - - S ko:K07507 - ko00000,ko02000 MgtC family
HKNFCEOD_00147 1.46e-149 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HKNFCEOD_00150 5.74e-106 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_00154 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HKNFCEOD_00155 0.0 - - - L - - - ATPase domain of DNA mismatch repair MUTS family
HKNFCEOD_00156 2.99e-144 ung2 - - L - - - Uracil-DNA glycosylase
HKNFCEOD_00157 1.29e-168 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HKNFCEOD_00158 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 C-terminal domain of alpha-glycerophosphate oxidase
HKNFCEOD_00159 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKNFCEOD_00160 8.48e-172 - - - M - - - Glycosyltransferase like family 2
HKNFCEOD_00161 3.3e-282 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKNFCEOD_00162 4.24e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HKNFCEOD_00163 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HKNFCEOD_00164 3.41e-218 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HKNFCEOD_00165 5.83e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HKNFCEOD_00168 1.27e-220 - - - L - - - Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKNFCEOD_00169 8.17e-103 - 2.7.1.204 - G ko:K20112 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_00170 5.42e-67 - 2.7.1.204 - G ko:K20113 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_00171 0.0 gatC - - G ko:K20114 ko02060,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HKNFCEOD_00172 2.82e-36 - - - - - - - -
HKNFCEOD_00173 2.22e-160 - - - S - - - Domain of unknown function (DUF4867)
HKNFCEOD_00174 1.75e-225 lacC 2.7.1.144 - H ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HKNFCEOD_00175 4.19e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
HKNFCEOD_00176 1.3e-121 lacB 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
HKNFCEOD_00177 1.25e-96 lacA 5.3.1.26 - G ko:K01819 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 Ribose/Galactose Isomerase
HKNFCEOD_00178 4.13e-181 - - - K ko:K02530 - ko00000,ko03000 DeoR C terminal sensor domain
HKNFCEOD_00179 3.73e-150 - - - S - - - HAD hydrolase, family IA, variant
HKNFCEOD_00180 4.78e-272 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKNFCEOD_00181 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 Putative exonuclease SbcCD, C subunit
HKNFCEOD_00182 6.8e-21 - - - - - - - -
HKNFCEOD_00183 7.42e-112 hsp1 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKNFCEOD_00185 4.79e-271 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific adenine glycosylase
HKNFCEOD_00186 2.23e-191 - - - I - - - alpha/beta hydrolase fold
HKNFCEOD_00187 1.5e-156 yrkL - - S - - - Flavodoxin-like fold
HKNFCEOD_00189 1.83e-113 - - - S - - - Short repeat of unknown function (DUF308)
HKNFCEOD_00190 1.92e-153 - - - S - - - Psort location Cytoplasmic, score
HKNFCEOD_00191 9.5e-199 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HKNFCEOD_00192 1.94e-251 - - - - - - - -
HKNFCEOD_00194 1.39e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HKNFCEOD_00195 0.0 bglB 3.2.1.21, 3.2.1.52 GH3 G ko:K01207,ko:K05349 ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501 ko00000,ko00001,ko00002,ko01000 hydrolase, family 3
HKNFCEOD_00196 3.06e-213 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
HKNFCEOD_00197 5.43e-209 XK27_00670 - - S ko:K01989,ko:K05832 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_00198 5.61e-207 WQ51_06230 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HKNFCEOD_00199 3.37e-180 - - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00200 4.78e-222 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding dehydrogenase
HKNFCEOD_00201 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 Cation transporter/ATPase, N-terminus
HKNFCEOD_00202 1.9e-231 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 2
HKNFCEOD_00203 0.0 ykcB - - M - - - Dolichyl-phosphate-mannose-protein mannosyltransferase
HKNFCEOD_00204 3.08e-93 - - - S - - - GtrA-like protein
HKNFCEOD_00205 3.91e-159 ciaR - - K ko:K14983 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
HKNFCEOD_00206 3.66e-310 ciaH 2.7.13.3 - T ko:K14982 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HKNFCEOD_00207 2.42e-88 - - - S - - - Belongs to the HesB IscA family
HKNFCEOD_00208 0.0 - - - QT - - - PucR C-terminal helix-turn-helix domain
HKNFCEOD_00209 1.52e-206 - - - S - - - KR domain
HKNFCEOD_00210 1.41e-204 adc 4.1.1.4 - Q ko:K01574 ko00072,ko00640,ko01100,map00072,map00640,map01100 ko00000,ko00001,ko00002,ko01000 Acetoacetate decarboxylase (ADC)
HKNFCEOD_00211 5.12e-180 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HKNFCEOD_00212 4.66e-206 - - - G - - - Xylose isomerase-like TIM barrel
HKNFCEOD_00213 1.58e-76 - - - - - - - -
HKNFCEOD_00214 8.04e-140 - - - - - - - -
HKNFCEOD_00216 1.9e-104 rgpAc - GT4 M ko:K12996 - ko00000,ko01000,ko01003,ko01005 Domain of unknown function (DUF1972)
HKNFCEOD_00217 1.52e-119 - - - M - - - Glycosyltransferase, group 1 family protein
HKNFCEOD_00218 0.0 - - - S - - - Protein of unknown function (DUF1524)
HKNFCEOD_00219 4.1e-222 - - - L - - - Belongs to the 'phage' integrase family
HKNFCEOD_00220 2.59e-47 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HKNFCEOD_00222 8.19e-131 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HKNFCEOD_00223 8.14e-79 - - - S - - - MucBP domain
HKNFCEOD_00224 9.73e-109 - - - - - - - -
HKNFCEOD_00226 1.02e-58 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HKNFCEOD_00227 3.18e-18 - - - - - - - -
HKNFCEOD_00228 3.79e-153 - - - K - - - Helix-turn-helix domain, rpiR family
HKNFCEOD_00229 2.57e-109 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKNFCEOD_00230 9.06e-60 - - - L - - - BRCA1 C Terminus (BRCT) domain
HKNFCEOD_00231 1.34e-147 - - - L - - - Resolvase, N terminal domain
HKNFCEOD_00232 2.7e-65 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HKNFCEOD_00233 4.96e-44 - - - L - - - RelB antitoxin
HKNFCEOD_00234 4.21e-95 - - - - - - - -
HKNFCEOD_00236 4.36e-93 - - - - - - - -
HKNFCEOD_00237 1.42e-22 - - - - - - - -
HKNFCEOD_00238 6.6e-83 - - - - - - - -
HKNFCEOD_00239 7.49e-117 yrxA - - S ko:K07105 - ko00000 3H domain
HKNFCEOD_00240 1.39e-113 ytxH - - S - - - YtxH-like protein
HKNFCEOD_00241 2.12e-46 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKNFCEOD_00242 6.86e-198 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HKNFCEOD_00243 8.01e-200 - - - S ko:K08974 - ko00000 Domain of unknown function (DUF368)
HKNFCEOD_00244 9.32e-112 ykuL - - S - - - CBS domain
HKNFCEOD_00245 1.9e-175 gla - - U ko:K02440 - ko00000,ko02000 Major intrinsic protein
HKNFCEOD_00246 1.64e-125 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HKNFCEOD_00247 0.0 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HKNFCEOD_00248 1.66e-111 yslB - - S - - - Protein of unknown function (DUF2507)
HKNFCEOD_00249 8.29e-312 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKNFCEOD_00250 6.97e-49 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKNFCEOD_00251 9.86e-304 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HKNFCEOD_00252 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKNFCEOD_00253 1.04e-27 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HKNFCEOD_00254 3.64e-70 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKNFCEOD_00255 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKNFCEOD_00256 3.16e-88 cvpA - - S - - - Colicin V production protein
HKNFCEOD_00257 2.84e-48 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKNFCEOD_00258 1.3e-69 yrzB - - S - - - Belongs to the UPF0473 family
HKNFCEOD_00259 2.67e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKNFCEOD_00260 4.89e-58 yrzL - - S - - - Belongs to the UPF0297 family
HKNFCEOD_00262 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKNFCEOD_00263 3.12e-223 - - - - - - - -
HKNFCEOD_00264 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKNFCEOD_00265 3.03e-229 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HKNFCEOD_00266 1.13e-307 ytoI - - K - - - DRTGG domain
HKNFCEOD_00267 3.44e-262 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKNFCEOD_00268 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKNFCEOD_00269 2.06e-150 mntR - - K ko:K03709 - ko00000,ko03000 Helix-turn-helix diphteria tox regulatory element
HKNFCEOD_00270 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HKNFCEOD_00271 1.76e-85 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HKNFCEOD_00272 3.46e-289 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKNFCEOD_00273 7.52e-263 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKNFCEOD_00274 4.54e-241 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKNFCEOD_00275 2.95e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKNFCEOD_00276 1.3e-136 yjbF - - S - - - SNARE associated Golgi protein
HKNFCEOD_00277 1.69e-112 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKNFCEOD_00278 2.41e-283 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HKNFCEOD_00279 4.49e-97 - - - S - - - Protein of unknown function (DUF3290)
HKNFCEOD_00280 4.49e-151 yviA - - S - - - Protein of unknown function (DUF421)
HKNFCEOD_00281 1.02e-197 - - - S - - - Alpha beta hydrolase
HKNFCEOD_00282 4.76e-201 - - - - - - - -
HKNFCEOD_00283 2.52e-199 dkgB - - S - - - reductase
HKNFCEOD_00284 6.61e-110 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HKNFCEOD_00285 1.97e-230 ybcH - - D ko:K06889 - ko00000 Alpha beta
HKNFCEOD_00286 2.24e-101 - - - K - - - Transcriptional regulator
HKNFCEOD_00287 7.46e-157 XK27_05175 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 haloacid dehalogenase-like hydrolase
HKNFCEOD_00288 6.56e-255 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKNFCEOD_00289 4.89e-122 - - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKNFCEOD_00290 1.69e-58 - - - - - - - -
HKNFCEOD_00291 1.56e-230 - 3.4.11.5 - I ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 carboxylic ester hydrolase activity
HKNFCEOD_00292 0.0 yfgQ - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HKNFCEOD_00293 4.06e-107 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HKNFCEOD_00294 3.81e-170 - - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNFCEOD_00295 3.86e-78 - - - - - - - -
HKNFCEOD_00296 0.0 pepF - - E - - - Oligopeptidase F
HKNFCEOD_00297 4.6e-113 - - - C - - - FMN binding
HKNFCEOD_00298 8.23e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKNFCEOD_00299 3.58e-217 mleP - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HKNFCEOD_00300 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HKNFCEOD_00301 5.92e-202 mleR - - K - - - LysR family
HKNFCEOD_00302 2.2e-223 - - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HKNFCEOD_00303 5.7e-80 yeaO - - S - - - Protein of unknown function, DUF488
HKNFCEOD_00304 3.8e-130 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKNFCEOD_00305 3.4e-91 - - - - - - - -
HKNFCEOD_00306 1.45e-116 - - - S - - - Flavin reductase like domain
HKNFCEOD_00307 8.47e-214 mleP2 - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HKNFCEOD_00308 9.83e-64 - - - - - - - -
HKNFCEOD_00309 9.86e-146 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKNFCEOD_00310 1.58e-33 - - - - - - - -
HKNFCEOD_00311 5.77e-267 XK27_05220 - - S - - - AI-2E family transporter
HKNFCEOD_00312 1.79e-104 - - - - - - - -
HKNFCEOD_00313 1.32e-71 - - - - - - - -
HKNFCEOD_00315 6.74e-244 - 1.1.1.1, 1.6.5.5 - C ko:K00001,ko:K00344 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKNFCEOD_00316 4.91e-55 - - - - - - - -
HKNFCEOD_00317 2.7e-62 ygbF - - S - - - Sugar efflux transporter for intercellular exchange
HKNFCEOD_00318 1.17e-77 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HKNFCEOD_00319 1.86e-244 - - - K - - - DNA-binding helix-turn-helix protein
HKNFCEOD_00321 1.84e-262 lldD 1.13.12.4 - C ko:K00467 ko00620,map00620 ko00000,ko00001,ko01000 IMP dehydrogenase / GMP reductase domain
HKNFCEOD_00322 1.29e-144 ydgI - - C - - - Nitroreductase family
HKNFCEOD_00323 2.19e-165 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HKNFCEOD_00325 4.58e-221 - 2.7.7.49 - L ko:K00986 - ko00000,ko01000 PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKNFCEOD_00333 8.3e-123 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 DNA-templated transcription, initiation
HKNFCEOD_00334 3.11e-120 yjdB - - S - - - Domain of unknown function (DUF4767)
HKNFCEOD_00336 1.28e-96 - - - L - - - COG3547 Transposase and inactivated derivatives
HKNFCEOD_00337 5.8e-160 - - - L - - - Transposase, IS116 IS110 IS902 family
HKNFCEOD_00339 3.23e-193 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HKNFCEOD_00340 1.19e-258 - - - S - - - DUF218 domain
HKNFCEOD_00341 5.33e-124 M1-431 - - S - - - Protein of unknown function (DUF1706)
HKNFCEOD_00342 8.63e-192 - - - I - - - NAD binding domain of 6-phosphogluconate dehydrogenase
HKNFCEOD_00343 1.81e-156 malR - - KT ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 cheY-homologous receiver domain
HKNFCEOD_00344 0.0 dpiB 2.7.13.3 - T ko:K02476,ko:K11614 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Single cache domain 3
HKNFCEOD_00345 5.39e-292 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 2-hydroxycarboxylate transporter family
HKNFCEOD_00346 3.65e-272 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HKNFCEOD_00347 1.49e-61 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HKNFCEOD_00348 2.37e-146 - - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HKNFCEOD_00349 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Fumarase C C-terminus
HKNFCEOD_00350 7.44e-187 - 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HKNFCEOD_00351 1.34e-126 thgA3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HKNFCEOD_00352 2.11e-273 - - - M - - - Glycosyl transferases group 1
HKNFCEOD_00353 0.0 yebA - - E - - - Transglutaminase/protease-like homologues
HKNFCEOD_00354 1.06e-235 - - - S - - - Protein of unknown function DUF58
HKNFCEOD_00355 3.51e-180 - - - S ko:K03924 - ko00000,ko01000 ATPase family associated with various cellular activities (AAA)
HKNFCEOD_00356 3.68e-136 - - - S ko:K06384 - ko00000 Stage II sporulation protein M
HKNFCEOD_00357 9.37e-129 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKNFCEOD_00358 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_00359 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_00360 1.09e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00361 3.22e-214 - - - G - - - Phosphotransferase enzyme family
HKNFCEOD_00362 7.76e-186 - - - S - - - AAA ATPase domain
HKNFCEOD_00363 0.0 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
HKNFCEOD_00364 8.68e-106 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HKNFCEOD_00365 1.4e-69 - - - - - - - -
HKNFCEOD_00366 4.19e-53 - - - S - - - Iron-sulphur cluster biosynthesis
HKNFCEOD_00367 5.43e-166 - - - S - - - Protein of unknown function (DUF975)
HKNFCEOD_00368 1.21e-304 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKNFCEOD_00369 4.51e-41 - - - - - - - -
HKNFCEOD_00370 3.81e-172 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00371 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00373 6.17e-204 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
HKNFCEOD_00374 8.33e-193 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_00375 1.03e-242 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
HKNFCEOD_00377 9.77e-279 - - - EGP - - - Major facilitator Superfamily
HKNFCEOD_00378 1.44e-230 manL 2.7.1.191, 2.7.1.202 - G ko:K02769,ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_00379 1.57e-171 manM - - G ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HKNFCEOD_00380 2.45e-216 manN - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HKNFCEOD_00381 1.08e-84 manO - - S - - - Domain of unknown function (DUF956)
HKNFCEOD_00382 2.11e-220 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HKNFCEOD_00383 6.56e-273 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HKNFCEOD_00384 0.0 - - - EGP - - - Major Facilitator Superfamily
HKNFCEOD_00385 1.92e-147 ycaC - - Q - - - Isochorismatase family
HKNFCEOD_00386 1.11e-118 - - - S - - - AAA domain
HKNFCEOD_00387 1.84e-110 - - - F - - - NUDIX domain
HKNFCEOD_00388 1.82e-140 yokL3 - - J - - - Acetyltransferase (GNAT) domain
HKNFCEOD_00389 8.36e-72 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HKNFCEOD_00390 5.01e-69 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_00391 1.97e-168 gntR - - K ko:K03489 - ko00000,ko03000 UTRA
HKNFCEOD_00392 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_00393 9.09e-97 - - - S - - - Domain of unknown function (DUF3284)
HKNFCEOD_00394 1.6e-271 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HKNFCEOD_00395 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HKNFCEOD_00396 1.63e-298 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKNFCEOD_00397 0.0 arpJ - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00398 7.15e-156 - 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Alpha/beta hydrolase family
HKNFCEOD_00399 3.03e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HKNFCEOD_00400 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKNFCEOD_00401 0.0 yycH - - S - - - YycH protein
HKNFCEOD_00402 1.05e-182 yycI - - S - - - YycH protein
HKNFCEOD_00403 4.32e-196 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HKNFCEOD_00404 1.7e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HKNFCEOD_00405 2.35e-92 - - - S - - - Iron-sulphur cluster biosynthesis
HKNFCEOD_00406 1.8e-99 hsp3 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HKNFCEOD_00407 0.0 cadA - - P - - - P-type ATPase
HKNFCEOD_00408 3.4e-133 - - - - - - - -
HKNFCEOD_00410 6.99e-242 - - - L ko:K07482 - ko00000 PFAM Integrase, catalytic core
HKNFCEOD_00412 2.81e-106 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_00413 1.43e-117 ydhK - - M - - - Protein of unknown function (DUF1541)
HKNFCEOD_00414 1.22e-140 - - - L - - - Transposase DDE domain group 1
HKNFCEOD_00422 1.02e-63 lciIC - - K - - - Helix-turn-helix domain
HKNFCEOD_00424 5.14e-169 - - - K - - - DeoR C terminal sensor domain
HKNFCEOD_00426 2.66e-170 zmp3 - - O - - - Zinc-dependent metalloprotease
HKNFCEOD_00427 0.0 - - - M - - - LysM domain
HKNFCEOD_00428 3.05e-19 - 2.7.1.39 - S ko:K02204 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Phosphotransferase enzyme family
HKNFCEOD_00429 3.24e-89 - - - S - - - Iron-sulphur cluster biosynthesis
HKNFCEOD_00431 6.16e-55 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
HKNFCEOD_00432 5.59e-127 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
HKNFCEOD_00433 5.19e-130 - - - V ko:K06147,ko:K06148,ko:K11085,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter transmembrane region
HKNFCEOD_00434 0.0 - - - V - - - ABC transporter transmembrane region
HKNFCEOD_00435 1.07e-48 - - - - - - - -
HKNFCEOD_00436 6.09e-70 - - - K - - - Transcriptional
HKNFCEOD_00437 2.82e-163 - - - S - - - DJ-1/PfpI family
HKNFCEOD_00438 0.0 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HKNFCEOD_00439 9.89e-214 - - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_00440 2.38e-226 - - - EP ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKNFCEOD_00442 1.69e-255 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HKNFCEOD_00443 1.15e-204 - - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HKNFCEOD_00444 1.01e-122 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKNFCEOD_00445 6.86e-90 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_00446 1.77e-174 - - - - - - - -
HKNFCEOD_00447 1.32e-15 - - - - - - - -
HKNFCEOD_00448 1.32e-160 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_00449 4.71e-81 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HKNFCEOD_00450 4.73e-209 - - - S - - - Alpha beta hydrolase
HKNFCEOD_00451 3.17e-107 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_00452 1.4e-114 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_00453 2.86e-161 - - - S ko:K07090 - ko00000 membrane transporter protein
HKNFCEOD_00454 0.0 - - - EGP - - - Major Facilitator
HKNFCEOD_00455 9.43e-146 - - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HKNFCEOD_00456 0.0 - - - M ko:K01992 - ko00000,ko00002,ko02000 Exporter of polyketide antibiotics
HKNFCEOD_00457 1.93e-214 ybhF_1 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_00458 6.35e-177 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HKNFCEOD_00459 4.93e-113 ORF00048 - - - - - - -
HKNFCEOD_00460 1.13e-75 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HKNFCEOD_00461 1.83e-135 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HKNFCEOD_00462 3.35e-111 - - - K - - - GNAT family
HKNFCEOD_00463 3.65e-133 kptA - - J ko:K07559 - ko00000,ko01000,ko03016 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HKNFCEOD_00464 2.97e-54 - - - - - - - -
HKNFCEOD_00465 1.43e-307 citM - - C ko:K03300 - ko00000 Citrate transporter
HKNFCEOD_00466 2.14e-69 - - - - - - - -
HKNFCEOD_00467 1.71e-62 oadG - - I - - - Biotin-requiring enzyme
HKNFCEOD_00468 5.58e-251 oadB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Na+-transporting oxaloacetate decarboxylase beta subunit
HKNFCEOD_00469 3.26e-07 - - - - - - - -
HKNFCEOD_00470 1.01e-226 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKNFCEOD_00471 3.41e-65 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HKNFCEOD_00472 8.71e-200 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HKNFCEOD_00473 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HKNFCEOD_00474 1e-120 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKNFCEOD_00475 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Conserved carboxylase domain
HKNFCEOD_00476 1.39e-161 citR - - K - - - FCD
HKNFCEOD_00477 1.34e-197 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKNFCEOD_00478 7.43e-97 - - - - - - - -
HKNFCEOD_00479 5.67e-42 - - - - - - - -
HKNFCEOD_00480 4.9e-199 - - - I - - - alpha/beta hydrolase fold
HKNFCEOD_00481 1.42e-204 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKNFCEOD_00482 2e-148 sodA 1.15.1.1 - C ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKNFCEOD_00483 1.43e-25 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HKNFCEOD_00484 8.02e-114 - - - - - - - -
HKNFCEOD_00485 1.36e-245 - - - S - - - Protein of unknown function C-terminal (DUF3324)
HKNFCEOD_00486 8.44e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HKNFCEOD_00487 4.81e-127 - - - - - - - -
HKNFCEOD_00488 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HKNFCEOD_00489 1.39e-168 budA 4.1.1.5 - Q ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HKNFCEOD_00491 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HKNFCEOD_00492 0.0 - - - K - - - Mga helix-turn-helix domain
HKNFCEOD_00493 0.0 - - - K - - - Mga helix-turn-helix domain
HKNFCEOD_00494 8.99e-293 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKNFCEOD_00501 1.98e-50 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HKNFCEOD_00502 4.95e-47 - 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_00503 1.09e-190 - 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 Mannitol dehydrogenase C-terminal domain
HKNFCEOD_00504 2.71e-70 - - - C - - - nitroreductase
HKNFCEOD_00505 3.21e-304 proP - - EGP ko:K03761,ko:K03762 - ko00000,ko02000 Sugar (and other) transporter
HKNFCEOD_00507 1.33e-17 - - - S - - - YvrJ protein family
HKNFCEOD_00508 3.57e-179 - - - M - - - hydrolase, family 25
HKNFCEOD_00509 1.26e-112 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_00510 4.67e-237 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00511 1.01e-153 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00512 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HKNFCEOD_00513 6.17e-193 - - - S - - - hydrolase
HKNFCEOD_00514 1.49e-58 - - - S ko:K19157 - ko00000,ko01000,ko02048 Bacterial toxin of type II toxin-antitoxin system, YafQ
HKNFCEOD_00515 1.35e-236 - - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HKNFCEOD_00516 2.1e-109 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_00517 2.18e-177 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_00518 7.9e-196 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKNFCEOD_00519 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HKNFCEOD_00520 1.7e-87 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_00521 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKNFCEOD_00522 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HKNFCEOD_00523 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HKNFCEOD_00525 0.0 pip - - V ko:K01421 - ko00000 domain protein
HKNFCEOD_00526 7.16e-130 pip - - V ko:K01421 - ko00000 domain protein
HKNFCEOD_00527 0.0 - - - GK - - - helix_turn_helix, arabinose operon control protein
HKNFCEOD_00528 2.26e-242 - - - G - - - Major Facilitator Superfamily
HKNFCEOD_00529 0.0 - - - S ko:K12941 - ko00000,ko01002 Peptidase dimerisation domain
HKNFCEOD_00530 7.46e-199 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKNFCEOD_00531 5.84e-253 - 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HKNFCEOD_00532 1.75e-105 - - - - - - - -
HKNFCEOD_00533 0.0 l1n 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HKNFCEOD_00534 7.24e-23 - - - - - - - -
HKNFCEOD_00535 2.03e-130 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_00536 6.02e-78 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_00537 2.35e-132 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HKNFCEOD_00538 1.47e-242 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HKNFCEOD_00539 7.81e-67 - - - O - - - OsmC-like protein
HKNFCEOD_00540 0.0 - - - L - - - Exonuclease
HKNFCEOD_00541 5.14e-65 yczG - - K - - - Helix-turn-helix domain
HKNFCEOD_00542 5.23e-258 yceJ - - EGP ko:K08221 - ko00000,ko02000 transporter
HKNFCEOD_00543 4.89e-139 ydfF - - K - - - Transcriptional
HKNFCEOD_00544 2.28e-138 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HKNFCEOD_00545 5.36e-215 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HKNFCEOD_00546 0.0 cidC 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKNFCEOD_00548 7.9e-246 pbpE - - V - - - Beta-lactamase
HKNFCEOD_00549 3.81e-191 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HKNFCEOD_00550 1.29e-184 - - - H - - - Protein of unknown function (DUF1698)
HKNFCEOD_00551 1.1e-157 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HKNFCEOD_00552 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 Glutamine synthetase, catalytic domain
HKNFCEOD_00553 1.19e-282 - - - S ko:K07045 - ko00000 Amidohydrolase
HKNFCEOD_00554 0.0 - - - E - - - Amino acid permease
HKNFCEOD_00555 9.74e-98 - - - K - - - helix_turn_helix, mercury resistance
HKNFCEOD_00556 1.46e-205 - - - S - - - reductase
HKNFCEOD_00557 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HKNFCEOD_00558 7.58e-134 tnpR1 - - L - - - Resolvase, N terminal domain
HKNFCEOD_00559 4.15e-49 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00560 5.31e-143 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKNFCEOD_00561 8.3e-110 yebR 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HKNFCEOD_00562 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKNFCEOD_00563 3.53e-271 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HKNFCEOD_00564 1.42e-287 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKNFCEOD_00565 1.24e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKNFCEOD_00566 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKNFCEOD_00567 2.55e-307 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HKNFCEOD_00568 8.07e-148 - - - S - - - Haloacid dehalogenase-like hydrolase
HKNFCEOD_00569 1.97e-152 radC - - L ko:K03630 - ko00000 DNA repair protein
HKNFCEOD_00570 4.82e-229 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HKNFCEOD_00571 1.88e-191 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HKNFCEOD_00572 8.66e-113 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HKNFCEOD_00573 2.69e-148 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKNFCEOD_00574 8.63e-182 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HKNFCEOD_00575 4.79e-142 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00576 3.29e-146 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
HKNFCEOD_00577 2.32e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HKNFCEOD_00578 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKNFCEOD_00579 7.11e-60 - - - - - - - -
HKNFCEOD_00580 9.34e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HKNFCEOD_00581 6.77e-219 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKNFCEOD_00582 1.6e-68 ftsL - - D - - - cell division protein FtsL
HKNFCEOD_00583 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HKNFCEOD_00584 1.09e-229 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKNFCEOD_00585 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKNFCEOD_00586 9.42e-258 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKNFCEOD_00587 5.91e-200 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKNFCEOD_00588 1.44e-311 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKNFCEOD_00589 6.55e-291 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKNFCEOD_00590 5.95e-101 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKNFCEOD_00591 5.58e-60 ylmG - - S ko:K02221 - ko00000,ko02044 integral membrane protein
HKNFCEOD_00592 1.45e-186 ylmH - - S - - - S4 domain protein
HKNFCEOD_00593 8.49e-120 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA protein
HKNFCEOD_00594 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKNFCEOD_00595 4.62e-48 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HKNFCEOD_00596 5.93e-207 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HKNFCEOD_00597 0.0 ydiC1 - - EGP - - - Major Facilitator
HKNFCEOD_00598 7.29e-270 yaaN - - P - - - Toxic anion resistance protein (TelA)
HKNFCEOD_00599 8.03e-151 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKNFCEOD_00600 6.12e-123 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HKNFCEOD_00601 2.86e-39 - - - - - - - -
HKNFCEOD_00602 1.95e-159 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKNFCEOD_00603 3.99e-278 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HKNFCEOD_00604 1.21e-75 XK27_04120 - - S - - - Putative amino acid metabolism
HKNFCEOD_00605 0.0 uvrA2 - - L - - - ABC transporter
HKNFCEOD_00606 3.67e-73 uvrA2 - - L - - - ABC transporter
HKNFCEOD_00607 4.09e-304 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKNFCEOD_00609 4.69e-159 pgm6 - - G - - - phosphoglycerate mutase
HKNFCEOD_00610 3.26e-151 - - - S - - - repeat protein
HKNFCEOD_00611 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKNFCEOD_00612 1.65e-311 - - - S - - - Sterol carrier protein domain
HKNFCEOD_00613 1.15e-232 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HKNFCEOD_00614 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKNFCEOD_00615 2.02e-43 ykzG - - S - - - Belongs to the UPF0356 family
HKNFCEOD_00616 1.11e-95 - - - - - - - -
HKNFCEOD_00617 7.04e-63 - - - - - - - -
HKNFCEOD_00618 1.23e-42 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_00621 1.47e-07 - - - - - - - -
HKNFCEOD_00622 5.12e-117 - - - - - - - -
HKNFCEOD_00623 4.85e-65 - - - - - - - -
HKNFCEOD_00624 1.34e-108 - - - C - - - Flavodoxin
HKNFCEOD_00625 5.54e-50 - - - - - - - -
HKNFCEOD_00626 2.82e-36 - - - - - - - -
HKNFCEOD_00627 2.86e-219 - 1.1.1.26 - CH ko:K00015 ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNFCEOD_00628 2.27e-94 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
HKNFCEOD_00629 4.95e-53 - - - S - - - Transglycosylase associated protein
HKNFCEOD_00630 1.16e-112 - - - S - - - Protein conserved in bacteria
HKNFCEOD_00631 4.15e-34 - - - - - - - -
HKNFCEOD_00632 8.12e-90 asp23 - - S - - - Asp23 family, cell envelope-related function
HKNFCEOD_00633 1.97e-92 asp2 - - S - - - Asp23 family, cell envelope-related function
HKNFCEOD_00634 2.66e-147 - - - S - - - Protein of unknown function (DUF969)
HKNFCEOD_00635 1.42e-195 - - - S - - - Protein of unknown function (DUF979)
HKNFCEOD_00636 6.93e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKNFCEOD_00637 1.02e-137 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 NADP oxidoreductase coenzyme F420-dependent
HKNFCEOD_00638 1.35e-164 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HKNFCEOD_00639 4.01e-87 - - - - - - - -
HKNFCEOD_00640 2.27e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HKNFCEOD_00641 6.29e-185 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKNFCEOD_00642 1.49e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HKNFCEOD_00643 1.11e-201 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HKNFCEOD_00644 3.26e-40 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HKNFCEOD_00645 9.76e-237 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKNFCEOD_00646 8.29e-168 - - - S - - - Protein of unknown function (DUF1129)
HKNFCEOD_00647 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKNFCEOD_00648 2.29e-153 - - - - - - - -
HKNFCEOD_00649 1.38e-155 vanR - - K - - - response regulator
HKNFCEOD_00650 2.81e-278 hpk31 - - T - - - Histidine kinase
HKNFCEOD_00651 3.9e-303 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HKNFCEOD_00652 1.02e-103 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKNFCEOD_00653 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKNFCEOD_00654 2.71e-182 racD 5.1.1.13 - G ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HKNFCEOD_00655 8.2e-211 yvgN - - C - - - Aldo keto reductase
HKNFCEOD_00656 1.27e-186 gntR - - K - - - rpiR family
HKNFCEOD_00657 3.48e-215 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HKNFCEOD_00658 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HKNFCEOD_00659 6.55e-270 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HKNFCEOD_00660 8.14e-313 - - - S - - - O-antigen ligase like membrane protein
HKNFCEOD_00661 2.06e-192 - - - S - - - Glycosyl transferase family 2
HKNFCEOD_00662 1.07e-164 welB - - S - - - Glycosyltransferase like family 2
HKNFCEOD_00663 4.32e-201 - - - S - - - Glycosyltransferase like family 2
HKNFCEOD_00664 3.38e-190 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HKNFCEOD_00665 0.0 - - - M - - - Glycosyl hydrolases family 25
HKNFCEOD_00666 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HKNFCEOD_00667 1.85e-207 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HKNFCEOD_00668 2.58e-253 - - - S - - - Protein conserved in bacteria
HKNFCEOD_00669 3.74e-75 - - - - - - - -
HKNFCEOD_00670 1.01e-167 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKNFCEOD_00671 3.46e-172 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HKNFCEOD_00672 4.23e-211 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HKNFCEOD_00673 1.52e-205 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 Dehydrogenase
HKNFCEOD_00674 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HKNFCEOD_00675 4.84e-256 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKNFCEOD_00676 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKNFCEOD_00677 3.46e-103 - - - T - - - Sh3 type 3 domain protein
HKNFCEOD_00678 7.68e-174 glcR - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HKNFCEOD_00679 2.32e-188 - - - M - - - Glycosyltransferase like family 2
HKNFCEOD_00680 1.8e-173 - - - S - - - Protein of unknown function (DUF975)
HKNFCEOD_00681 4.42e-54 - - - - - - - -
HKNFCEOD_00682 1.26e-139 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HKNFCEOD_00683 2.78e-222 draG - - O - - - ADP-ribosylglycohydrolase
HKNFCEOD_00684 0.0 - - - S - - - ABC transporter
HKNFCEOD_00685 5.88e-175 ypaC - - Q - - - Methyltransferase domain
HKNFCEOD_00686 0.0 - - - S - - - Bacterial membrane protein YfhO
HKNFCEOD_00687 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
HKNFCEOD_00688 1.42e-218 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HKNFCEOD_00689 8.56e-133 - - - - - - - -
HKNFCEOD_00690 8.49e-217 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HKNFCEOD_00692 6.22e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HKNFCEOD_00693 9.32e-107 yvbK - - K - - - GNAT family
HKNFCEOD_00694 2.4e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HKNFCEOD_00695 5.35e-133 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKNFCEOD_00696 6.23e-303 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HKNFCEOD_00697 3.86e-260 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKNFCEOD_00698 9.74e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKNFCEOD_00699 7.65e-136 - - - - - - - -
HKNFCEOD_00700 7.04e-136 - - - - - - - -
HKNFCEOD_00701 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKNFCEOD_00702 3.2e-143 vanZ - - V - - - VanZ like family
HKNFCEOD_00703 4.66e-196 glcU - - U ko:K05340 - ko00000,ko02000 sugar transport
HKNFCEOD_00704 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HKNFCEOD_00705 1.21e-287 - - - L - - - Pfam:Integrase_AP2
HKNFCEOD_00706 7.81e-42 - - - - - - - -
HKNFCEOD_00707 2.8e-92 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HKNFCEOD_00708 2.33e-25 - - - - - - - -
HKNFCEOD_00709 7.43e-142 - - - S - - - Domain of Unknown Function with PDB structure (DUF3862)
HKNFCEOD_00711 7.07e-32 - - - S - - - sequence-specific DNA binding
HKNFCEOD_00712 2.02e-14 - - - K - - - Helix-turn-helix domain
HKNFCEOD_00713 1.15e-13 - - - - - - - -
HKNFCEOD_00714 1.08e-20 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HKNFCEOD_00716 2.21e-127 - - - - - - - -
HKNFCEOD_00720 1.98e-198 recT - - L ko:K07455 - ko00000,ko03400 RecT family
HKNFCEOD_00721 2.63e-190 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HKNFCEOD_00722 1e-159 - - - L - - - Replication initiation and membrane attachment
HKNFCEOD_00723 6.67e-158 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HKNFCEOD_00725 6.78e-58 - - - - - - - -
HKNFCEOD_00726 8.04e-74 - - - S - - - Protein of unknown function (DUF1064)
HKNFCEOD_00727 5.59e-35 - - - - - - - -
HKNFCEOD_00730 8.06e-54 - - - - - - - -
HKNFCEOD_00734 1.3e-32 - - - - - - - -
HKNFCEOD_00735 1.19e-20 - - - - - - - -
HKNFCEOD_00739 2.06e-40 - - - S - - - YopX protein
HKNFCEOD_00742 1.46e-68 - - - - - - - -
HKNFCEOD_00744 1.34e-278 - - - S - - - GcrA cell cycle regulator
HKNFCEOD_00746 1.2e-119 - - - L ko:K07474 - ko00000 Terminase small subunit
HKNFCEOD_00747 4.59e-315 - - - S - - - Terminase-like family
HKNFCEOD_00748 0.0 - - - S - - - Phage portal protein
HKNFCEOD_00749 2.79e-227 - - - S - - - head morphogenesis protein, SPP1 gp7 family
HKNFCEOD_00752 7.98e-36 - - - - - - - -
HKNFCEOD_00753 2.13e-110 - - - S - - - Domain of unknown function (DUF4355)
HKNFCEOD_00754 4.78e-62 - - - - - - - -
HKNFCEOD_00755 3.73e-238 - - - S - - - Phage major capsid protein E
HKNFCEOD_00756 1.32e-194 - - - - - - - -
HKNFCEOD_00757 2.08e-79 - - - S - - - Phage gp6-like head-tail connector protein
HKNFCEOD_00758 1.57e-65 - - - - - - - -
HKNFCEOD_00759 3.11e-75 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HKNFCEOD_00760 4.75e-92 - - - S - - - Protein of unknown function (DUF3168)
HKNFCEOD_00761 6.62e-126 - - - S - - - Phage tail tube protein
HKNFCEOD_00762 8.96e-68 - - - S - - - Phage tail assembly chaperone protein, TAC
HKNFCEOD_00763 2.83e-73 - - - - - - - -
HKNFCEOD_00764 0.0 - - - D - - - Phage tail tape measure protein
HKNFCEOD_00765 3.15e-103 terS - - L - - - Phage terminase, small subunit
HKNFCEOD_00766 0.0 terL - - S - - - overlaps another CDS with the same product name
HKNFCEOD_00767 3e-29 - - - - - - - -
HKNFCEOD_00768 5.1e-284 - - - S - - - Phage portal protein
HKNFCEOD_00769 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
HKNFCEOD_00770 8.23e-62 - - - S - - - Phage gp6-like head-tail connector protein
HKNFCEOD_00771 2.3e-23 - - - - - - - -
HKNFCEOD_00772 1.4e-35 ytgB - - S - - - Transglycosylase associated protein
HKNFCEOD_00774 1.87e-217 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKNFCEOD_00775 2.32e-233 - - - D ko:K06889 - ko00000 Alpha beta
HKNFCEOD_00776 8.78e-238 lipA - - I - - - Carboxylesterase family
HKNFCEOD_00777 1.68e-275 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HKNFCEOD_00778 9.2e-101 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_00779 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 Mga helix-turn-helix domain
HKNFCEOD_00780 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_00781 2.09e-169 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKNFCEOD_00782 3.86e-192 - - - S - - - haloacid dehalogenase-like hydrolase
HKNFCEOD_00783 5.93e-59 - - - - - - - -
HKNFCEOD_00784 6.72e-19 - - - - - - - -
HKNFCEOD_00785 1.51e-238 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKNFCEOD_00786 2.9e-160 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_00787 3.59e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HKNFCEOD_00788 0.0 - - - M - - - Leucine rich repeats (6 copies)
HKNFCEOD_00789 1.04e-251 ypjH - - C ko:K08317 - ko00000,ko01000 dehydrogenase
HKNFCEOD_00790 4.21e-286 amd - - E - - - Peptidase family M20/M25/M40
HKNFCEOD_00791 1.48e-104 - - - S - - - Threonine/Serine exporter, ThrE
HKNFCEOD_00792 3.8e-175 labL - - S - - - Putative threonine/serine exporter
HKNFCEOD_00794 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKNFCEOD_00795 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKNFCEOD_00797 5.79e-170 jag - - S ko:K06346 - ko00000 R3H domain protein
HKNFCEOD_00798 4.53e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKNFCEOD_00799 2.99e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKNFCEOD_00800 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HKNFCEOD_00801 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKNFCEOD_00802 4.16e-260 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKNFCEOD_00803 4.07e-43 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HKNFCEOD_00804 9.09e-260 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKNFCEOD_00805 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNFCEOD_00806 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKNFCEOD_00807 3.02e-162 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKNFCEOD_00808 5.2e-98 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKNFCEOD_00809 1.36e-65 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HKNFCEOD_00810 1.54e-114 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKNFCEOD_00811 3.26e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKNFCEOD_00812 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome bd terminal oxidase subunit I
HKNFCEOD_00813 3.29e-228 - - - C - - - Cytochrome bd terminal oxidase subunit II
HKNFCEOD_00814 8.07e-40 - - - - - - - -
HKNFCEOD_00815 9.81e-138 - - - S - - - Protein of unknown function (DUF1211)
HKNFCEOD_00818 5.26e-183 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKNFCEOD_00819 1.53e-44 - 2.7.1.203 - G ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_00820 5.86e-10 - - - G - - - PTS system fructose IIA component
HKNFCEOD_00821 2.05e-261 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HKNFCEOD_00822 2.11e-31 - - - K - - - AraC-like ligand binding domain
HKNFCEOD_00823 2.01e-212 kbaY 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HKNFCEOD_00824 8.69e-195 manZ - - G ko:K02796,ko:K02815 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HKNFCEOD_00825 3.93e-184 - - - U ko:K02746,ko:K02795,ko:K02814 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_00826 6.77e-111 - 2.7.1.206 - G ko:K02813 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_00827 1.24e-89 - 2.7.1.206 - G ko:K02812 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_00828 1.01e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HKNFCEOD_00829 2.98e-220 - - - K - - - sugar-binding domain protein
HKNFCEOD_00830 7.05e-312 - - - E ko:K19956 ko00051,map00051 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HKNFCEOD_00831 5.41e-171 - - - K ko:K03710 - ko00000,ko03000 UTRA
HKNFCEOD_00832 5.82e-130 hxlB 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 sugar phosphate isomerase involved in capsule formation
HKNFCEOD_00833 5.39e-152 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
HKNFCEOD_00834 1.77e-237 - 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HKNFCEOD_00835 1.05e-146 dhaL 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 - S ko:K00863,ko:K05879 ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622 ko00000,ko00001,ko00002,ko01000 Dak2
HKNFCEOD_00836 1.83e-279 mtlD 1.1.1.17 - C ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 mannitol-1-phosphate 5-dehydrogenase activity
HKNFCEOD_00837 5.44e-198 - - - G ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HKNFCEOD_00838 5.6e-170 - - - G ko:K17466 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_00839 5.98e-111 - 2.7.1.203 - G ko:K17465 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_00840 5.33e-98 - 2.7.1.191, 2.7.1.203 - G ko:K02793,ko:K17464 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_00841 1.44e-185 - 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HKNFCEOD_00842 0.0 - 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKNFCEOD_00843 4.92e-203 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HKNFCEOD_00844 0.0 - - - K - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_00845 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_00846 4.07e-292 malY 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase class I and II
HKNFCEOD_00847 0.0 pts31BC - - G ko:K11202,ko:K11203 - ko00000,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_00848 2.86e-97 - - - G ko:K11201 - ko00000,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_00849 0.0 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
HKNFCEOD_00850 1.4e-173 - 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Pfam:DUF1498
HKNFCEOD_00851 2.14e-232 - - - G - - - Domain of unknown function (DUF4432)
HKNFCEOD_00852 1.42e-219 - - - G ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 Phosphotransferase System
HKNFCEOD_00853 1.08e-63 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_00854 1.44e-104 - 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_00855 2.11e-222 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HKNFCEOD_00856 3.02e-101 ptsN 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HKNFCEOD_00857 0.0 - - - K ko:K02538 - ko00000,ko03000 PRD domain
HKNFCEOD_00858 1.75e-299 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 Sigma-54 factor, core binding domain
HKNFCEOD_00859 0.0 - - - K ko:K19505 - ko00000,ko03000 Sigma-54 interaction domain
HKNFCEOD_00860 2.85e-89 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_00861 1.12e-116 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_00862 2.28e-172 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_00863 1.23e-193 - - - G ko:K02796,ko:K17467 ko00030,ko00051,ko00520,ko01100,ko01120,ko02060,map00030,map00051,map00520,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HKNFCEOD_00864 4.05e-205 estA - CE1 S ko:K03930 - ko00000,ko01000 Putative esterase
HKNFCEOD_00865 2.8e-173 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HKNFCEOD_00866 6.77e-116 - - - K - - - Acetyltransferase (GNAT) family
HKNFCEOD_00867 6.39e-300 dcuC - - C ko:K03326 - ko00000,ko02000 Tripartite ATP-independent periplasmic transporter, DctM component
HKNFCEOD_00868 4.26e-221 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HKNFCEOD_00869 5.25e-251 ydeM3 - - C ko:K06871 - ko00000 Iron-sulfur cluster-binding domain
HKNFCEOD_00870 2.44e-169 - - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HKNFCEOD_00871 1.89e-205 pkn1 - - S - - - Sulfatase-modifying factor enzyme 1
HKNFCEOD_00872 6.34e-282 - - - P - - - Type I phosphodiesterase / nucleotide pyrophosphatase
HKNFCEOD_00873 4.4e-112 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKNFCEOD_00874 3.55e-259 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKNFCEOD_00875 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKNFCEOD_00876 4.36e-264 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKNFCEOD_00877 3.43e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HKNFCEOD_00878 1.05e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKNFCEOD_00879 3.14e-164 yvqF - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HKNFCEOD_00880 1.33e-231 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKNFCEOD_00881 2.04e-149 vraR - - K ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HKNFCEOD_00882 8.3e-70 yneR - - S - - - Belongs to the HesB IscA family
HKNFCEOD_00883 0.0 - - - S - - - Bacterial membrane protein YfhO
HKNFCEOD_00884 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HKNFCEOD_00885 5.43e-157 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HKNFCEOD_00886 1.88e-52 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HKNFCEOD_00887 1.13e-228 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HKNFCEOD_00888 1.93e-96 yqhL - - P - - - Rhodanese-like protein
HKNFCEOD_00889 3.33e-35 WQ51_02665 - - S - - - Protein of unknown function (DUF3042)
HKNFCEOD_00890 2.57e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKNFCEOD_00891 1.36e-303 ynbB - - P - - - aluminum resistance
HKNFCEOD_00892 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
HKNFCEOD_00893 1.32e-80 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 Transcriptional regulator
HKNFCEOD_00894 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HKNFCEOD_00895 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKNFCEOD_00897 6.05e-40 - - - - - - - -
HKNFCEOD_00898 1.17e-16 - - - - - - - -
HKNFCEOD_00899 5.83e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HKNFCEOD_00900 1.77e-74 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HKNFCEOD_00901 1.6e-63 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HKNFCEOD_00902 2.4e-256 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKNFCEOD_00903 6.06e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKNFCEOD_00904 9.44e-99 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HKNFCEOD_00905 1.93e-87 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKNFCEOD_00906 7.39e-192 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKNFCEOD_00907 1.56e-295 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNFCEOD_00908 1.42e-43 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKNFCEOD_00909 9.01e-190 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKNFCEOD_00910 8.09e-197 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HKNFCEOD_00911 4.19e-96 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HKNFCEOD_00912 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HKNFCEOD_00914 2.71e-66 - - - - - - - -
HKNFCEOD_00915 2.34e-117 - - - S ko:K07001 - ko00000 Patatin-like phospholipase
HKNFCEOD_00916 2.52e-148 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HKNFCEOD_00917 1.77e-47 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKNFCEOD_00918 1.33e-273 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKNFCEOD_00919 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKNFCEOD_00920 9.71e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKNFCEOD_00921 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKNFCEOD_00922 5.22e-174 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HKNFCEOD_00923 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HKNFCEOD_00924 5.6e-221 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKNFCEOD_00925 4.86e-150 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HKNFCEOD_00926 2.52e-164 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HKNFCEOD_00927 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HKNFCEOD_00928 5.83e-75 yloU - - S - - - Asp23 family, cell envelope-related function
HKNFCEOD_00929 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HKNFCEOD_00930 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKNFCEOD_00931 1.35e-239 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKNFCEOD_00932 3.21e-49 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKNFCEOD_00933 4.24e-247 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_00934 1.62e-228 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_00935 3.2e-216 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_00936 1.16e-193 oppC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_00937 0.0 oppA1 - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HKNFCEOD_00938 2.8e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKNFCEOD_00939 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HKNFCEOD_00940 1.06e-231 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKNFCEOD_00941 7.91e-70 - - - - - - - -
HKNFCEOD_00943 1.26e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKNFCEOD_00944 2.16e-303 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKNFCEOD_00945 2.97e-59 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HKNFCEOD_00946 1.55e-51 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HKNFCEOD_00947 1.25e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKNFCEOD_00948 1.76e-185 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HKNFCEOD_00949 2e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKNFCEOD_00950 3.28e-28 - - - - - - - -
HKNFCEOD_00951 2.84e-48 ynzC - - S - - - UPF0291 protein
HKNFCEOD_00952 1.39e-40 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HKNFCEOD_00953 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_00954 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_00955 4.28e-181 yejC - - S - - - Protein of unknown function (DUF1003)
HKNFCEOD_00956 1.59e-291 yhdG - - E ko:K03294 - ko00000 Amino Acid
HKNFCEOD_00957 8.45e-160 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HKNFCEOD_00958 2.05e-168 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HKNFCEOD_00959 4.43e-60 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HKNFCEOD_00960 1.18e-182 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HKNFCEOD_00961 1.63e-200 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKNFCEOD_00962 5.86e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HKNFCEOD_00963 4.96e-121 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKNFCEOD_00964 1.24e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKNFCEOD_00965 7.66e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HKNFCEOD_00966 3.52e-292 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HKNFCEOD_00967 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKNFCEOD_00968 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKNFCEOD_00969 1.33e-110 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HKNFCEOD_00970 1.68e-276 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HKNFCEOD_00971 1.13e-59 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HKNFCEOD_00972 1.06e-59 ylxQ - - J - - - ribosomal protein
HKNFCEOD_00973 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKNFCEOD_00974 1.27e-76 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKNFCEOD_00975 2.58e-182 terC - - P - - - Integral membrane protein TerC family
HKNFCEOD_00976 3.3e-212 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKNFCEOD_00977 6.32e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HKNFCEOD_00978 8.81e-288 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HKNFCEOD_00979 1.6e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKNFCEOD_00980 3.18e-127 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKNFCEOD_00981 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HKNFCEOD_00982 3.84e-260 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKNFCEOD_00983 2.19e-178 - - - V - - - ABC transporter transmembrane region
HKNFCEOD_00984 3.04e-64 - - - K ko:K20373 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
HKNFCEOD_00985 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKNFCEOD_00986 1.32e-33 - - - - - - - -
HKNFCEOD_00987 5.87e-109 - - - S - - - ASCH
HKNFCEOD_00989 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKNFCEOD_00990 2.67e-308 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HKNFCEOD_00991 5.75e-72 - - - - - - - -
HKNFCEOD_00993 0.0 - - - S - - - Putative threonine/serine exporter
HKNFCEOD_00994 7.02e-59 spiA - - K - - - TRANSCRIPTIONal
HKNFCEOD_00995 2.5e-57 - - - S - - - Enterocin A Immunity
HKNFCEOD_00996 6.69e-61 - - - S - - - Enterocin A Immunity
HKNFCEOD_00997 2.99e-176 - - - - - - - -
HKNFCEOD_00998 6.77e-81 - - - - - - - -
HKNFCEOD_00999 2.4e-71 padR - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HKNFCEOD_01000 6.16e-145 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_01001 9.85e-263 - - - S - - - Protein of unknown function (DUF2974)
HKNFCEOD_01002 1.32e-293 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HKNFCEOD_01003 6.33e-133 - - - - - - - -
HKNFCEOD_01004 0.0 - - - M - - - domain protein
HKNFCEOD_01005 8.26e-307 - - - - - - - -
HKNFCEOD_01006 0.0 - - - M - - - Cna protein B-type domain
HKNFCEOD_01007 1.56e-189 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HKNFCEOD_01008 2.79e-295 - - - S - - - Membrane
HKNFCEOD_01009 2.57e-55 - - - - - - - -
HKNFCEOD_01011 3.82e-191 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKNFCEOD_01012 1.56e-277 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKNFCEOD_01013 8.53e-287 - - - EGP - - - Transmembrane secretion effector
HKNFCEOD_01014 5.02e-52 - - - - - - - -
HKNFCEOD_01015 1.5e-44 - - - - - - - -
HKNFCEOD_01017 1.59e-28 yhjA - - K - - - CsbD-like
HKNFCEOD_01018 3.59e-21 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKNFCEOD_01019 5.76e-225 lctO 1.13.12.4 - C ko:K00467,ko:K10530 ko00620,map00620 ko00000,ko00001,ko01000 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKNFCEOD_01020 5.25e-61 - - - - - - - -
HKNFCEOD_01021 4.71e-263 - - - S - - - Bacterial low temperature requirement A protein (LtrA)
HKNFCEOD_01022 1.19e-158 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKNFCEOD_01023 8.84e-120 ccpN - - K - - - Domain in cystathionine beta-synthase and other proteins.
HKNFCEOD_01024 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
HKNFCEOD_01025 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HKNFCEOD_01026 1.17e-213 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_01027 3.52e-275 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_01028 6.05e-251 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HKNFCEOD_01029 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HKNFCEOD_01030 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HKNFCEOD_01031 5.93e-93 - - - S - - - Protein of unknown function (DUF805)
HKNFCEOD_01032 1e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HKNFCEOD_01033 4.85e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTPase
HKNFCEOD_01034 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKNFCEOD_01035 5.49e-261 yacL - - S - - - domain protein
HKNFCEOD_01036 6.91e-203 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01037 1.85e-168 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_01038 1.43e-125 pncA - - Q - - - Isochorismatase family
HKNFCEOD_01039 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKNFCEOD_01040 7.33e-271 ugpC 3.6.3.20 - E ko:K05816,ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_01041 1.3e-210 - - - P ko:K05814 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type sugar transport systems, permease components
HKNFCEOD_01042 5.9e-192 ugpE - - G ko:K05815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_01043 0.0 ugpB - - G ko:K05813 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKNFCEOD_01044 2.24e-96 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKNFCEOD_01045 9.3e-156 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HKNFCEOD_01046 2.19e-124 - - - K - - - Helix-turn-helix domain
HKNFCEOD_01048 2e-72 ps105 - - - - - - -
HKNFCEOD_01049 3.62e-121 yveA - - Q - - - Isochorismatase family
HKNFCEOD_01050 2.75e-116 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_01051 5.22e-244 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HKNFCEOD_01052 4.66e-34 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HKNFCEOD_01053 1.65e-46 chaT1 - - U ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HKNFCEOD_01054 5.08e-131 laaE - - K - - - Transcriptional regulator PadR-like family
HKNFCEOD_01055 1.31e-113 - - - M ko:K03828 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HKNFCEOD_01056 1.4e-263 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HKNFCEOD_01057 1.67e-272 - - - EGP - - - Transporter, major facilitator family protein
HKNFCEOD_01058 0.0 - 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
HKNFCEOD_01059 2.59e-170 - - - K ko:K03710 - ko00000,ko03000 UTRA
HKNFCEOD_01060 0.0 - - - E - - - Peptidase family M20/M25/M40
HKNFCEOD_01061 1.1e-232 asnA2 3.5.1.1 - E ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HKNFCEOD_01062 8.07e-204 - - - GK - - - ROK family
HKNFCEOD_01063 1.54e-101 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01064 1.55e-140 - 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HKNFCEOD_01066 1.92e-63 frvA 2.7.1.202 - G ko:K02768 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01067 1.03e-50 - 2.7.1.202 - G ko:K02769 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01068 1.31e-196 - - - G - - - Phosphotransferase System
HKNFCEOD_01069 4.59e-275 ulaG - - S ko:K03476 ko00053,ko01100,ko01120,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Beta-lactamase superfamily domain
HKNFCEOD_01070 4.89e-105 - 2.7.1.194 - G ko:K02821 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01071 0.0 sgaT - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HKNFCEOD_01072 3.36e-61 sgaB 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01073 5.26e-148 ulaD 4.1.1.85, 4.1.2.43 - G ko:K03078,ko:K08093 ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
HKNFCEOD_01074 8.64e-178 - - - K - - - DeoR C terminal sensor domain
HKNFCEOD_01075 1.53e-212 sga 5.1.3.22 - G ko:K03079 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Xylose isomerase-like TIM barrel
HKNFCEOD_01076 1.45e-193 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HKNFCEOD_01077 9.07e-177 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HKNFCEOD_01078 4.13e-185 srlD2 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 NAD dependent epimerase/dehydratase family
HKNFCEOD_01079 0.0 srlM - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HKNFCEOD_01080 7.54e-115 srlM1 - - K - - - Glucitol operon activator protein (GutM)
HKNFCEOD_01081 5.81e-131 srlA - - G ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system enzyme II sorbitol-specific factor
HKNFCEOD_01082 1.95e-250 srlE 2.7.1.198 - G ko:K02782,ko:K02783 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Sorbitol phosphotransferase enzyme II N-terminus
HKNFCEOD_01083 2.24e-84 - 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HKNFCEOD_01084 3.56e-160 - - - H - - - Pfam:Transaldolase
HKNFCEOD_01085 0.0 - - - K - - - Mga helix-turn-helix domain
HKNFCEOD_01086 5.21e-74 - - - S - - - PRD domain
HKNFCEOD_01087 8.65e-81 - - - S - - - Glycine-rich SFCGS
HKNFCEOD_01088 1.1e-76 - - - S - - - Domain of unknown function (DUF4312)
HKNFCEOD_01089 2.37e-176 - - - S - - - Domain of unknown function (DUF4311)
HKNFCEOD_01090 3.79e-155 - - - S - - - Domain of unknown function (DUF4310)
HKNFCEOD_01091 2.12e-275 dho 3.5.2.3 - S ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Amidohydrolase family
HKNFCEOD_01092 1.76e-259 selA 2.9.1.1 - H ko:K01042 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko01000 L-seryl-tRNA selenium transferase
HKNFCEOD_01093 1.61e-176 - 4.1.2.14 - S ko:K17463 ko00030,ko01100,ko01120,map00030,map01100,map01120 ko00000,ko00001,ko00002,ko01000 KDGP aldolase
HKNFCEOD_01094 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HKNFCEOD_01103 6.81e-241 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKNFCEOD_01104 1.42e-268 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKNFCEOD_01106 1.35e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HKNFCEOD_01107 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HKNFCEOD_01109 1.84e-113 - - - S - - - Phospholipase A2
HKNFCEOD_01110 2.57e-120 - - - EG - - - EamA-like transporter family
HKNFCEOD_01111 1.11e-96 - - - L - - - NUDIX domain
HKNFCEOD_01112 8.13e-82 - - - - - - - -
HKNFCEOD_01113 5.59e-249 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKNFCEOD_01114 6.96e-239 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKNFCEOD_01115 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HKNFCEOD_01116 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKNFCEOD_01117 4.4e-116 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKNFCEOD_01118 9.09e-282 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKNFCEOD_01119 6.02e-216 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKNFCEOD_01120 2.21e-179 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKNFCEOD_01122 7.06e-81 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKNFCEOD_01124 3.31e-207 lysR - - K - - - Transcriptional regulator
HKNFCEOD_01125 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HKNFCEOD_01126 1e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HKNFCEOD_01127 8.85e-47 - - - - - - - -
HKNFCEOD_01128 2.2e-223 serA 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKNFCEOD_01129 2.69e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HKNFCEOD_01131 9.68e-86 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKNFCEOD_01132 6.54e-138 ypsA - - S - - - Belongs to the UPF0398 family
HKNFCEOD_01133 1.47e-156 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKNFCEOD_01134 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HKNFCEOD_01135 5.94e-111 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HKNFCEOD_01136 7.61e-148 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKNFCEOD_01137 3.19e-146 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HKNFCEOD_01138 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HKNFCEOD_01139 1.15e-279 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HKNFCEOD_01140 3.5e-112 ypmB - - S - - - Protein conserved in bacteria
HKNFCEOD_01142 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HKNFCEOD_01143 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HKNFCEOD_01144 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKNFCEOD_01145 2.26e-216 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HKNFCEOD_01146 4.46e-230 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HKNFCEOD_01147 6.21e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKNFCEOD_01148 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HKNFCEOD_01149 1.88e-223 - - - - - - - -
HKNFCEOD_01150 3.71e-183 - - - - - - - -
HKNFCEOD_01151 2.32e-79 yitW - - S - - - Iron-sulfur cluster assembly protein
HKNFCEOD_01152 2.03e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HKNFCEOD_01153 1.4e-191 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKNFCEOD_01154 1.14e-160 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HKNFCEOD_01155 9.19e-249 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKNFCEOD_01156 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKNFCEOD_01157 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HKNFCEOD_01158 1.48e-219 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HKNFCEOD_01159 5.29e-284 sip - - L - - - Phage integrase family
HKNFCEOD_01162 6.52e-269 - - - M - - - Glycosyl hydrolases family 25
HKNFCEOD_01163 1.49e-61 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HKNFCEOD_01164 1.23e-41 - - - - - - - -
HKNFCEOD_01166 1.56e-34 - - - - - - - -
HKNFCEOD_01167 1.16e-31 - - - S - - - cellulase activity
HKNFCEOD_01168 1.48e-246 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKNFCEOD_01169 1.4e-133 lemA - - S ko:K03744 - ko00000 LemA family
HKNFCEOD_01170 7.19e-157 - - - S ko:K06872 - ko00000 TPM domain
HKNFCEOD_01171 4.58e-305 dinF - - V - - - MatE
HKNFCEOD_01172 2.76e-120 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HKNFCEOD_01173 5.7e-196 - - - Q - - - Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HKNFCEOD_01174 2.48e-224 ydhF - - S - - - Aldo keto reductase
HKNFCEOD_01175 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKNFCEOD_01176 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKNFCEOD_01177 1.49e-222 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HKNFCEOD_01178 3.25e-203 ypuA - - S - - - Protein of unknown function (DUF1002)
HKNFCEOD_01179 4.7e-50 - - - - - - - -
HKNFCEOD_01180 1.31e-124 yxkA - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HKNFCEOD_01182 4.59e-219 - - - - - - - -
HKNFCEOD_01183 6.41e-24 - - - - - - - -
HKNFCEOD_01184 8.06e-165 cobB - - K ko:K12410 - ko00000,ko01000 Sir2 family
HKNFCEOD_01185 9.14e-139 yiiE - - S - - - Protein of unknown function (DUF1211)
HKNFCEOD_01186 3.11e-218 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HKNFCEOD_01187 1.09e-118 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HKNFCEOD_01188 5.93e-196 yunF - - F - - - Protein of unknown function DUF72
HKNFCEOD_01189 4.11e-223 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HKNFCEOD_01190 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKNFCEOD_01191 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HKNFCEOD_01192 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HKNFCEOD_01193 2.89e-199 - - - T - - - GHKL domain
HKNFCEOD_01194 4.8e-159 - - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HKNFCEOD_01195 5.82e-219 yqhA - - G - - - Aldose 1-epimerase
HKNFCEOD_01196 1.35e-239 lacD 4.1.2.40 - G ko:K01635 ko00052,ko01100,ko02024,map00052,map01100,map02024 ko00000,ko00001,ko01000 Belongs to the aldolase LacD family
HKNFCEOD_01197 7.36e-104 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 - G ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112 ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000,ko03000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HKNFCEOD_01198 9.1e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HKNFCEOD_01199 6.78e-130 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKNFCEOD_01200 1.18e-201 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKNFCEOD_01201 4.13e-51 veg - - S - - - Biofilm formation stimulator VEG
HKNFCEOD_01202 6.63e-232 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKNFCEOD_01203 1.99e-205 czcD - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HKNFCEOD_01204 5.89e-158 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HKNFCEOD_01205 7.49e-154 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01206 1.01e-193 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HKNFCEOD_01207 8.48e-285 ysaA - - V - - - RDD family
HKNFCEOD_01208 9.43e-299 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKNFCEOD_01209 2.2e-225 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKNFCEOD_01210 4.42e-73 nudA - - S - - - ASCH
HKNFCEOD_01211 1.88e-244 - - - E - - - glutamate:sodium symporter activity
HKNFCEOD_01212 6.63e-297 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HKNFCEOD_01213 2.24e-264 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HKNFCEOD_01214 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKNFCEOD_01215 1.17e-33 - - - T - - - PFAM SpoVT AbrB
HKNFCEOD_01217 2.01e-116 - - - - - - - -
HKNFCEOD_01218 1.71e-285 dgoD 4.2.1.6, 4.2.1.8 - M ko:K01684,ko:K08323 ko00040,ko00052,ko01100,ko01120,map00040,map00052,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Mandelate racemase muconate lactonizing enzyme
HKNFCEOD_01219 3.29e-313 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HKNFCEOD_01220 2.9e-61 sgcB 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01221 1.76e-104 - 2.7.1.200 - GT ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01222 5.89e-138 - 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HKNFCEOD_01223 0.0 - - - G - - - Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01224 5.54e-59 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HKNFCEOD_01225 1e-63 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01226 0.0 bgl 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKNFCEOD_01227 9.02e-139 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HKNFCEOD_01228 4.82e-315 - - - S ko:K09704 - ko00000 Metal-independent alpha-mannosidase (GH125)
HKNFCEOD_01229 0.0 mngB 3.2.1.170 GH38 G ko:K15524 - ko00000,ko01000 Glycosyl hydrolases family 38 N-terminal domain
HKNFCEOD_01230 1.54e-307 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_01231 1.1e-172 - - - K ko:K03492 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HKNFCEOD_01232 1.51e-175 - 4.1.2.17 - G ko:K01628 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Class II Aldolase and Adducin N-terminal domain
HKNFCEOD_01234 0.0 pts36C - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HKNFCEOD_01235 2.53e-67 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01236 1.49e-107 pts36A 2.7.1.200 - G ko:K02773 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01237 1.35e-169 rdrB - - K ko:K02444,ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HKNFCEOD_01238 7.58e-212 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HKNFCEOD_01239 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 L-rhamnose isomerase (RhaA)
HKNFCEOD_01240 6.94e-69 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HKNFCEOD_01241 0.0 rhaB 2.7.1.5 - F ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKNFCEOD_01242 2.08e-301 iolF - - P ko:K06610 - ko00000,ko02000 Sugar (and other) transporter
HKNFCEOD_01243 9.25e-226 - - - K - - - helix_turn_helix, arabinose operon control protein
HKNFCEOD_01244 2.27e-270 adhC 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HKNFCEOD_01245 1.59e-157 - - - E - - - Porphyromonas-type peptidyl-arginine deiminase
HKNFCEOD_01246 2.86e-207 - - - J - - - Methyltransferase domain
HKNFCEOD_01247 0.0 - 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKNFCEOD_01250 0.0 - - - M - - - Right handed beta helix region
HKNFCEOD_01251 4.52e-97 - - - - - - - -
HKNFCEOD_01252 0.0 - - - M - - - Heparinase II/III N-terminus
HKNFCEOD_01253 6.79e-285 - - - V - - - ABC transporter transmembrane region
HKNFCEOD_01254 7.7e-276 - - - S - - - nuclear-transcribed mRNA catabolic process, no-go decay
HKNFCEOD_01255 4.47e-98 - - - S - - - NUDIX domain
HKNFCEOD_01257 8.18e-26 - - - - - - - -
HKNFCEOD_01258 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKNFCEOD_01259 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HKNFCEOD_01261 0.0 bmr3 - - EGP - - - Major Facilitator
HKNFCEOD_01262 4.77e-130 yobS - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_01263 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
HKNFCEOD_01264 4.22e-60 - - - S - - - Thiamine-binding protein
HKNFCEOD_01265 6.39e-177 - - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HKNFCEOD_01266 1.16e-204 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HKNFCEOD_01267 1.07e-282 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNFCEOD_01268 0.0 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HKNFCEOD_01269 1.1e-76 - - - - - - - -
HKNFCEOD_01270 1.36e-221 - - - S - - - Protein of unknown function (DUF805)
HKNFCEOD_01271 0.0 - - - L - - - Mga helix-turn-helix domain
HKNFCEOD_01273 8.47e-243 ynjC - - S - - - Cell surface protein
HKNFCEOD_01274 2.04e-171 - - - S - - - WxL domain surface cell wall-binding
HKNFCEOD_01275 6.99e-168 - - - S - - - WxL domain surface cell wall-binding
HKNFCEOD_01277 0.0 - - - - - - - -
HKNFCEOD_01278 4.96e-133 yoaA - - J - - - COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKNFCEOD_01279 2.32e-39 - - - - - - - -
HKNFCEOD_01280 6.83e-227 mhqA - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKNFCEOD_01281 1.2e-61 - - - S ko:K09004 - ko00000 DsrE/DsrF-like family
HKNFCEOD_01282 0.0 XK27_07275 - - S ko:K06901 - ko00000,ko02000 permease
HKNFCEOD_01283 1.4e-71 - - - S - - - Protein of unknown function (DUF1516)
HKNFCEOD_01284 6.55e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HKNFCEOD_01285 1.17e-206 - 1.6.5.5 - C ko:K00344 - ko00000,ko01000 alcohol dehydrogenase
HKNFCEOD_01286 2.25e-111 - - - K - - - Transcriptional regulator
HKNFCEOD_01287 9.97e-59 - - - - - - - -
HKNFCEOD_01288 6.75e-245 ldhD3 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNFCEOD_01289 1.37e-114 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HKNFCEOD_01290 2.61e-261 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HKNFCEOD_01291 2.67e-56 - - - - - - - -
HKNFCEOD_01292 1.85e-266 mccF - - V - - - LD-carboxypeptidase
HKNFCEOD_01293 5.26e-234 yveB - - I - - - PAP2 superfamily
HKNFCEOD_01294 2.02e-56 - - - S - - - Protein of unknown function (DUF2089)
HKNFCEOD_01295 3.17e-51 - - - - - - - -
HKNFCEOD_01296 0.0 yvdP - - C - - - COG0277 FAD FMN-containing dehydrogenases
HKNFCEOD_01297 4.21e-49 - - - T - - - Calcineurin-like phosphoesterase superfamily domain
HKNFCEOD_01298 5.79e-194 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKNFCEOD_01299 6.64e-185 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HKNFCEOD_01300 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HKNFCEOD_01301 1.94e-86 spx2 - - P ko:K16509 - ko00000 ArsC family
HKNFCEOD_01302 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 phosphatase activity
HKNFCEOD_01303 1.29e-186 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKNFCEOD_01304 5.44e-132 - - - M - - - Sortase family
HKNFCEOD_01305 8.73e-262 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HKNFCEOD_01306 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKNFCEOD_01307 4.81e-255 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKNFCEOD_01308 5.92e-281 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HKNFCEOD_01309 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKNFCEOD_01310 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKNFCEOD_01311 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HKNFCEOD_01312 3.12e-222 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNFCEOD_01313 5.83e-73 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKNFCEOD_01314 1.32e-221 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKNFCEOD_01315 1.55e-312 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKNFCEOD_01316 4.01e-191 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HKNFCEOD_01317 2.85e-89 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_01318 2.09e-143 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HKNFCEOD_01319 1.56e-13 - - - - - - - -
HKNFCEOD_01320 3.91e-109 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HKNFCEOD_01322 1.05e-209 - - - - - - - -
HKNFCEOD_01323 2.59e-173 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01324 2.05e-189 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HKNFCEOD_01325 1.44e-141 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_01326 6.51e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_01327 9.34e-225 cps2D 5.1.3.2, 5.1.3.25 - M ko:K01784,ko:K17947 ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HKNFCEOD_01328 0.0 cps2E - - M - - - Bacterial sugar transferase
HKNFCEOD_01329 2.72e-167 - - - - - - - -
HKNFCEOD_01330 3.08e-208 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKNFCEOD_01331 1.55e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKNFCEOD_01332 3.98e-257 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNFCEOD_01333 4.54e-205 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKNFCEOD_01334 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HKNFCEOD_01335 6.61e-93 - - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HKNFCEOD_01336 1.28e-163 WQ51_05710 - - S - - - Mitochondrial biogenesis AIM24
HKNFCEOD_01337 1.21e-65 - - - - - - - -
HKNFCEOD_01338 3.28e-277 aspC 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKNFCEOD_01339 1.54e-220 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKNFCEOD_01340 1.23e-221 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HKNFCEOD_01341 2.67e-51 - - - - - - - -
HKNFCEOD_01342 1.86e-269 floL - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 SPFH domain / Band 7 family
HKNFCEOD_01343 0.0 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HKNFCEOD_01344 1.6e-290 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HKNFCEOD_01345 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HKNFCEOD_01346 4.1e-191 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKNFCEOD_01347 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HKNFCEOD_01348 2.6e-96 usp1 - - T - - - Universal stress protein family
HKNFCEOD_01349 1.63e-175 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
HKNFCEOD_01350 9.19e-285 gbuA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HKNFCEOD_01351 5.82e-189 gbuB - - E ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HKNFCEOD_01352 1.01e-215 gbuC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HKNFCEOD_01353 0.0 - 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKNFCEOD_01354 7.62e-219 - - - I - - - Diacylglycerol kinase catalytic domain
HKNFCEOD_01355 1.41e-85 gtcA2 - - S - - - Teichoic acid glycosylation protein
HKNFCEOD_01356 4.31e-166 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HKNFCEOD_01357 4.01e-240 ydbI - - K - - - AI-2E family transporter
HKNFCEOD_01358 2.41e-261 pbpX - - V - - - Beta-lactamase
HKNFCEOD_01359 1.09e-209 - - - S - - - zinc-ribbon domain
HKNFCEOD_01360 4.74e-30 - - - - - - - -
HKNFCEOD_01361 1.91e-167 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKNFCEOD_01362 3.85e-108 - - - F - - - NUDIX domain
HKNFCEOD_01363 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HKNFCEOD_01364 2.44e-135 - - - K - - - Transcriptional regulator, MarR family
HKNFCEOD_01365 1.83e-256 - - - - - - - -
HKNFCEOD_01366 2.79e-213 - - - S - - - Putative esterase
HKNFCEOD_01367 5.76e-14 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HKNFCEOD_01368 1.35e-88 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 MarR family
HKNFCEOD_01369 2.84e-63 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2316)
HKNFCEOD_01370 3.93e-117 hyuA - - EQ - - - Hydantoinase/oxoprolinase N-terminal region
HKNFCEOD_01371 6.84e-186 frlD1 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HKNFCEOD_01372 9.27e-77 - - - S - - - WxL domain surface cell wall-binding
HKNFCEOD_01373 4.36e-103 - - - - - - - -
HKNFCEOD_01374 0.0 - 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Helix-hairpin-helix containing domain
HKNFCEOD_01375 2.39e-175 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2087)
HKNFCEOD_01376 2.13e-173 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HKNFCEOD_01377 0.0 galA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HKNFCEOD_01378 0.0 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_01380 1.62e-90 - - - S - - - Domain of unknown function (DUF3284)
HKNFCEOD_01381 1.16e-264 ybhE - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HKNFCEOD_01382 1.09e-68 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system cellobiose-specific component IIA
HKNFCEOD_01383 2.39e-109 - - - - - - - -
HKNFCEOD_01384 1.7e-190 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HKNFCEOD_01385 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HKNFCEOD_01386 1.34e-170 lutC - - S ko:K00782 - ko00000 LUD domain
HKNFCEOD_01387 4.1e-130 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKNFCEOD_01388 0.0 - - - EGP - - - Major Facilitator Superfamily
HKNFCEOD_01389 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKNFCEOD_01390 1.4e-208 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKNFCEOD_01391 3.01e-227 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKNFCEOD_01392 2.89e-250 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_01393 2.59e-229 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HKNFCEOD_01394 2.15e-151 gpm5 - - G - - - Phosphoglycerate mutase family
HKNFCEOD_01395 6.56e-64 - - - K - - - sequence-specific DNA binding
HKNFCEOD_01396 2.1e-49 XK27_01315 - - S - - - Protein of unknown function (DUF2829)
HKNFCEOD_01397 1.55e-161 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HKNFCEOD_01398 4.2e-106 ccl - - S - - - QueT transporter
HKNFCEOD_01399 3.68e-170 - - - E - - - lipolytic protein G-D-S-L family
HKNFCEOD_01400 4.38e-137 epsB - - M - - - biosynthesis protein
HKNFCEOD_01401 8.2e-138 ywqD - - D - - - Capsular exopolysaccharide family
HKNFCEOD_01403 3.25e-74 - - - K - - - Helix-turn-helix domain
HKNFCEOD_01404 2.13e-185 ptp3 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HKNFCEOD_01405 5.06e-282 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Domain of unknown function (DUF1730)
HKNFCEOD_01406 1.54e-84 - - - - - - - -
HKNFCEOD_01407 7.09e-113 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HKNFCEOD_01408 5.77e-93 adhR - - K - - - helix_turn_helix, mercury resistance
HKNFCEOD_01409 2.59e-107 - - - C - - - Flavodoxin
HKNFCEOD_01410 2.68e-253 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HKNFCEOD_01411 6.48e-147 - - - GM - - - NmrA-like family
HKNFCEOD_01412 7.21e-17 - - - S - - - Protein of unknown function (DUF1211)
HKNFCEOD_01414 2.29e-131 - - - Q - - - methyltransferase
HKNFCEOD_01415 7.76e-143 - - - T - - - Sh3 type 3 domain protein
HKNFCEOD_01416 1.12e-150 - - - F - - - glutamine amidotransferase
HKNFCEOD_01417 7.42e-174 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2263)
HKNFCEOD_01418 0.0 yhdP - - S - - - Transporter associated domain
HKNFCEOD_01419 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HKNFCEOD_01420 1.69e-79 - - - S - - - Domain of unknown function (DUF4811)
HKNFCEOD_01421 2.04e-129 maf - - D ko:K06287 - ko00000 nucleoside-triphosphate diphosphatase activity
HKNFCEOD_01422 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKNFCEOD_01423 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKNFCEOD_01424 0.0 ydaO - - E - - - amino acid
HKNFCEOD_01425 5.32e-75 - - - S - - - Domain of unknown function (DUF1827)
HKNFCEOD_01426 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKNFCEOD_01427 1.7e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKNFCEOD_01428 1.44e-141 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKNFCEOD_01429 1.01e-251 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HKNFCEOD_01430 1.4e-221 - - - - - - - -
HKNFCEOD_01431 1.7e-203 - - - V ko:K01990,ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_01432 4.97e-81 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HKNFCEOD_01433 1.1e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKNFCEOD_01434 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HKNFCEOD_01435 3.12e-68 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01436 5.99e-243 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKNFCEOD_01437 8.44e-130 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HKNFCEOD_01438 3.82e-168 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HKNFCEOD_01439 2.08e-96 - - - - - - - -
HKNFCEOD_01440 2.42e-117 - - - T - - - ECF transporter, substrate-specific component
HKNFCEOD_01441 6.13e-232 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HKNFCEOD_01442 3.86e-185 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HKNFCEOD_01443 1.74e-191 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKNFCEOD_01444 7.92e-76 yabA - - L - - - Involved in initiation control of chromosome replication
HKNFCEOD_01445 5.36e-222 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HKNFCEOD_01446 1.14e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
HKNFCEOD_01447 1.45e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKNFCEOD_01448 2.95e-46 - - - S - - - Protein of unknown function (DUF2508)
HKNFCEOD_01449 1.26e-139 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKNFCEOD_01450 7e-49 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKNFCEOD_01451 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKNFCEOD_01452 4.38e-118 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKNFCEOD_01453 9.05e-67 - - - - - - - -
HKNFCEOD_01454 1.93e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HKNFCEOD_01455 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKNFCEOD_01456 1.15e-59 - - - - - - - -
HKNFCEOD_01457 1.49e-225 ccpB - - K - - - lacI family
HKNFCEOD_01458 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HKNFCEOD_01459 1.7e-205 - 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKNFCEOD_01461 1.37e-74 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKNFCEOD_01462 8.44e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKNFCEOD_01463 1.92e-283 mdtG - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HKNFCEOD_01464 2.87e-198 - - - K - - - acetyltransferase
HKNFCEOD_01465 1.4e-86 - - - - - - - -
HKNFCEOD_01466 1.19e-277 yceI - - G ko:K08369 - ko00000,ko02000 Sugar (and other) transporter
HKNFCEOD_01467 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HKNFCEOD_01468 1.89e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKNFCEOD_01469 6.87e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKNFCEOD_01470 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HKNFCEOD_01471 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HKNFCEOD_01472 3.48e-86 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HKNFCEOD_01473 8.09e-116 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobalamin adenosyltransferase
HKNFCEOD_01474 1.36e-125 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HKNFCEOD_01475 3.54e-82 - - - S - - - Domain of unknown function (DUF4430)
HKNFCEOD_01476 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
HKNFCEOD_01477 3.77e-102 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HKNFCEOD_01478 1.71e-205 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKNFCEOD_01479 2.29e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HKNFCEOD_01480 2.09e-30 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKNFCEOD_01481 4.4e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HKNFCEOD_01482 3.09e-218 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HKNFCEOD_01483 2.34e-214 menA 2.5.1.74 - M ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 UbiA prenyltransferase family
HKNFCEOD_01484 2.2e-252 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNFCEOD_01485 6.86e-187 cad - - S ko:K20379 ko02024,map02024 ko00000,ko00001 FMN_bind
HKNFCEOD_01486 0.0 ndh 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HKNFCEOD_01487 2.76e-104 - - - S - - - NusG domain II
HKNFCEOD_01488 1.03e-127 hepA 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase component I
HKNFCEOD_01489 1.05e-228 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKNFCEOD_01491 2.3e-158 - 1.5.1.40 - S ko:K06988 - ko00000,ko01000 Rossmann-like domain
HKNFCEOD_01492 1.48e-248 XK27_00915 - - C - - - Luciferase-like monooxygenase
HKNFCEOD_01494 1.02e-126 yacP - - S ko:K06962 - ko00000 YacP-like NYN domain
HKNFCEOD_01495 2.21e-181 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKNFCEOD_01496 4.83e-98 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKNFCEOD_01497 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HKNFCEOD_01498 0.0 loxD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 FAD linked oxidases, C-terminal domain
HKNFCEOD_01499 5.14e-137 - - - - - - - -
HKNFCEOD_01501 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKNFCEOD_01502 3.31e-237 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HKNFCEOD_01503 3.52e-151 rpiA1 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKNFCEOD_01504 1.73e-182 - - - K - - - SIS domain
HKNFCEOD_01505 2.64e-145 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HKNFCEOD_01506 6.8e-227 - - - S - - - Membrane
HKNFCEOD_01507 1.07e-81 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HKNFCEOD_01508 1.73e-288 inlJ - - M - - - MucBP domain
HKNFCEOD_01509 1.52e-123 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKNFCEOD_01510 3.15e-175 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HKNFCEOD_01511 8.74e-139 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKNFCEOD_01512 2.17e-159 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKNFCEOD_01513 1.59e-88 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKNFCEOD_01514 9.95e-211 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HKNFCEOD_01515 5.96e-207 yitL - - S ko:K00243 - ko00000 S1 domain
HKNFCEOD_01516 4.31e-95 ytwI - - S - - - Protein of unknown function (DUF441)
HKNFCEOD_01517 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HKNFCEOD_01518 2.21e-227 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKNFCEOD_01519 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HKNFCEOD_01520 8.1e-36 - - - S - - - Protein of unknown function (DUF2929)
HKNFCEOD_01521 2.47e-184 - - - - - - - -
HKNFCEOD_01522 0.0 ycjM 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
HKNFCEOD_01523 6.3e-123 - - - K - - - Domain of unknown function (DUF1836)
HKNFCEOD_01524 1.35e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HKNFCEOD_01525 0.0 clpB - - O ko:K03695 ko04213,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNFCEOD_01526 2.47e-65 - - - S - - - Lipopolysaccharide assembly protein A domain
HKNFCEOD_01527 1.83e-183 yqjQ - - S ko:K07124 - ko00000 Enoyl-(Acyl carrier protein) reductase
HKNFCEOD_01528 7.76e-233 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKNFCEOD_01529 0.0 oatA - - I - - - Acyltransferase
HKNFCEOD_01530 3.37e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKNFCEOD_01531 2.78e-170 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HKNFCEOD_01532 2.76e-218 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKNFCEOD_01533 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HKNFCEOD_01534 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKNFCEOD_01535 1.89e-172 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01536 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HKNFCEOD_01537 3.33e-28 - - - - - - - -
HKNFCEOD_01538 2.28e-63 - - - S - - - mazG nucleotide pyrophosphohydrolase
HKNFCEOD_01539 6.46e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HKNFCEOD_01540 1.66e-154 - - - S - - - WxL domain surface cell wall-binding
HKNFCEOD_01541 4.82e-78 - - - - - - - -
HKNFCEOD_01542 8.98e-141 - - - N - - - WxL domain surface cell wall-binding
HKNFCEOD_01543 0.0 - - - S - - - Leucine-rich repeat (LRR) protein
HKNFCEOD_01544 2.7e-222 yicL - - EG - - - EamA-like transporter family
HKNFCEOD_01545 0.0 - - - - - - - -
HKNFCEOD_01546 1.23e-185 CcmA5 - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_01547 5.54e-112 - - - S - - - ECF-type riboflavin transporter, S component
HKNFCEOD_01548 3.69e-192 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HKNFCEOD_01549 7.88e-211 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HKNFCEOD_01550 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKNFCEOD_01551 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01552 0.0 - - - V ko:K06147,ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_01553 3.34e-286 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HKNFCEOD_01554 1.56e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HKNFCEOD_01555 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKNFCEOD_01556 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKNFCEOD_01557 1.51e-283 sstT - - U ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HKNFCEOD_01558 0.0 - - - E ko:K03294 - ko00000 Amino Acid
HKNFCEOD_01559 1.13e-221 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
HKNFCEOD_01560 0.0 gdhA 1.4.1.4 - E ko:K00262 ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HKNFCEOD_01561 3.08e-43 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HKNFCEOD_01562 5.77e-87 - - - - - - - -
HKNFCEOD_01565 1.5e-55 - - - - - - - -
HKNFCEOD_01566 3e-69 - - - - - - - -
HKNFCEOD_01567 2.87e-181 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HKNFCEOD_01568 2.76e-216 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKNFCEOD_01569 1.38e-84 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKNFCEOD_01570 6.78e-82 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HKNFCEOD_01571 1.03e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKNFCEOD_01572 8.02e-230 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HKNFCEOD_01574 1.05e-87 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HKNFCEOD_01575 3.98e-29 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HKNFCEOD_01576 8.44e-199 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKNFCEOD_01577 3.37e-208 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKNFCEOD_01578 3.1e-216 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKNFCEOD_01579 7.27e-106 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HKNFCEOD_01580 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKNFCEOD_01581 3.25e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HKNFCEOD_01582 4.56e-47 XK27_04345 3.6.1.1 - C ko:K01507 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HKNFCEOD_01583 0.0 - - - - - - - -
HKNFCEOD_01584 2.88e-151 - - - V - - - ABC transporter
HKNFCEOD_01585 9.64e-109 - - - FG - - - adenosine 5'-monophosphoramidase activity
HKNFCEOD_01586 9.4e-313 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 N-acetylmuramoyl-L-alanine amidase
HKNFCEOD_01587 6.42e-149 - - - J - - - HAD-hyrolase-like
HKNFCEOD_01588 1.59e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKNFCEOD_01589 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKNFCEOD_01590 5.49e-58 - - - - - - - -
HKNFCEOD_01591 2.11e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKNFCEOD_01592 7.07e-222 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HKNFCEOD_01593 1e-112 XK27_03960 - - S - - - Protein of unknown function (DUF3013)
HKNFCEOD_01594 6.26e-144 - 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HKNFCEOD_01595 2.23e-50 - - - - - - - -
HKNFCEOD_01596 1.9e-86 - - - S - - - Protein of unknown function (DUF1093)
HKNFCEOD_01597 7.25e-213 - - - M - - - Peptidase_C39 like family
HKNFCEOD_01598 8.82e-124 - - - - - - - -
HKNFCEOD_01599 2.71e-299 - - - - - - - -
HKNFCEOD_01600 0.0 - - - S - - - Glucosyl transferase GtrII
HKNFCEOD_01601 4.98e-210 nodB3 - - G - - - Polysaccharide deacetylase
HKNFCEOD_01602 4.57e-304 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKNFCEOD_01603 5.76e-210 - - - I - - - Diacylglycerol kinase catalytic domain
HKNFCEOD_01604 0.0 - - - E - - - Amino Acid
HKNFCEOD_01605 2.68e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01606 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKNFCEOD_01607 4.03e-164 gpm2 - - G - - - Phosphoglycerate mutase family
HKNFCEOD_01608 8.14e-240 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HKNFCEOD_01609 6.29e-307 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKNFCEOD_01610 1.11e-106 yjhE - - S - - - Phage tail protein
HKNFCEOD_01611 8.04e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HKNFCEOD_01612 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HKNFCEOD_01613 7.47e-30 - - - - - - - -
HKNFCEOD_01614 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HKNFCEOD_01615 5.02e-110 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HKNFCEOD_01616 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKNFCEOD_01617 3.38e-56 - - - - - - - -
HKNFCEOD_01619 2.3e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HKNFCEOD_01620 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HKNFCEOD_01621 3.28e-175 - - - F - - - NUDIX domain
HKNFCEOD_01622 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HKNFCEOD_01623 2.06e-187 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HKNFCEOD_01624 3.75e-244 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HKNFCEOD_01625 1.04e-247 - - - V - - - Beta-lactamase
HKNFCEOD_01626 4.1e-197 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKNFCEOD_01627 3.72e-210 - - - K - - - Helix-turn-helix domain, rpiR family
HKNFCEOD_01628 1.67e-105 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_01629 1.56e-192 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKNFCEOD_01630 6.17e-177 XK27_08455 - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_01631 1.24e-258 - - - S - - - endonuclease exonuclease phosphatase family protein
HKNFCEOD_01632 6.53e-220 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HKNFCEOD_01633 9.27e-174 draG - - O - - - ADP-ribosylglycohydrolase
HKNFCEOD_01634 1.25e-67 sugE - - U ko:K11741 - ko00000,ko02000 Multidrug resistance protein
HKNFCEOD_01635 1.82e-172 - - - S - - - -acetyltransferase
HKNFCEOD_01636 6.5e-119 yfbM - - K - - - FR47-like protein
HKNFCEOD_01637 5.49e-119 - - - E - - - HAD-hyrolase-like
HKNFCEOD_01638 3.06e-238 - 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 nadph quinone reductase
HKNFCEOD_01639 3.52e-174 ptp1 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HKNFCEOD_01640 3.38e-104 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_01641 1.3e-106 yiaC - - K ko:K03826 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HKNFCEOD_01642 4.01e-100 - - - K ko:K03830 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HKNFCEOD_01643 1.01e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKNFCEOD_01644 5.19e-252 ysdE - - P - - - Citrate transporter
HKNFCEOD_01645 8.69e-91 - - - - - - - -
HKNFCEOD_01646 0.0 dapE 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Peptidase dimerisation domain
HKNFCEOD_01647 8.55e-213 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKNFCEOD_01648 1.63e-111 queT - - S - - - QueT transporter
HKNFCEOD_01649 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 GXGXG motif
HKNFCEOD_01650 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HKNFCEOD_01651 6.89e-168 yciB - - M - - - ErfK YbiS YcfS YnhG
HKNFCEOD_01652 1.34e-154 - - - S - - - (CBS) domain
HKNFCEOD_01653 0.0 - - - S - - - Putative peptidoglycan binding domain
HKNFCEOD_01654 5.04e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HKNFCEOD_01655 6.08e-131 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKNFCEOD_01656 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKNFCEOD_01657 0.0 yabM - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HKNFCEOD_01658 1.99e-53 yabO - - J - - - S4 domain protein
HKNFCEOD_01659 7.17e-87 divIC - - D ko:K05589,ko:K13052 - ko00000,ko03036 cell cycle
HKNFCEOD_01660 1.17e-105 yabR - - J ko:K07571 - ko00000 RNA binding
HKNFCEOD_01661 6.04e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKNFCEOD_01662 1.14e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HKNFCEOD_01663 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKNFCEOD_01664 4.36e-208 - - - S - - - WxL domain surface cell wall-binding
HKNFCEOD_01665 5.11e-209 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKNFCEOD_01666 5.32e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKNFCEOD_01667 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HKNFCEOD_01668 4.82e-132 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKNFCEOD_01669 5.13e-112 - - - S - - - E1-E2 ATPase
HKNFCEOD_01670 1.42e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HKNFCEOD_01671 1.15e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HKNFCEOD_01672 0.0 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKNFCEOD_01673 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HKNFCEOD_01674 4.32e-202 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 L-malate dehydrogenase activity
HKNFCEOD_01675 6.15e-62 yktA - - S - - - Belongs to the UPF0223 family
HKNFCEOD_01676 3.56e-189 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HKNFCEOD_01677 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HKNFCEOD_01678 1.66e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HKNFCEOD_01679 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKNFCEOD_01680 4.9e-83 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HKNFCEOD_01681 9.93e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HKNFCEOD_01682 1.79e-112 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKNFCEOD_01683 1.82e-233 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HKNFCEOD_01684 7.34e-148 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HKNFCEOD_01685 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HKNFCEOD_01686 7.21e-222 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HKNFCEOD_01687 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HKNFCEOD_01688 5e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKNFCEOD_01689 1.34e-62 - - - - - - - -
HKNFCEOD_01690 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKNFCEOD_01691 1.93e-213 - - - S - - - Tetratricopeptide repeat
HKNFCEOD_01692 4.73e-286 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKNFCEOD_01693 1.14e-231 trpD 2.4.2.18, 4.1.3.27 - F ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKNFCEOD_01694 1.73e-174 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HKNFCEOD_01695 7.2e-130 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HKNFCEOD_01696 8.28e-292 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKNFCEOD_01697 7.99e-182 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKNFCEOD_01698 8.68e-150 flp - - K ko:K21562 - ko00000,ko03000 helix_turn_helix, cAMP Regulatory protein
HKNFCEOD_01699 3.32e-128 dpsB - - P - - - Belongs to the Dps family
HKNFCEOD_01700 3.61e-46 copZ - - P - - - Heavy-metal-associated domain
HKNFCEOD_01701 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HKNFCEOD_01703 8.51e-286 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01704 2.28e-136 opuCB - - E ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_01705 3.55e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKNFCEOD_01706 5.58e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_01708 1.93e-139 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HKNFCEOD_01709 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HKNFCEOD_01710 6.43e-66 - - - K - - - TRANSCRIPTIONal
HKNFCEOD_01711 1.09e-306 - - - EGP - - - Major Facilitator
HKNFCEOD_01712 1.5e-298 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HKNFCEOD_01713 1.8e-41 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HKNFCEOD_01714 2.66e-207 - - - K - - - Transcriptional activator, Rgg GadR MutR family
HKNFCEOD_01715 1.16e-72 ps105 - - - - - - -
HKNFCEOD_01717 1.28e-161 kdgR - - K - - - FCD domain
HKNFCEOD_01718 6.62e-148 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HKNFCEOD_01719 2.51e-182 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKNFCEOD_01720 3.47e-40 - - - - - - - -
HKNFCEOD_01721 1.11e-251 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HKNFCEOD_01722 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HKNFCEOD_01723 3.16e-98 - - - - - - - -
HKNFCEOD_01724 2.02e-270 - - - - - - - -
HKNFCEOD_01725 0.0 pts26BCA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKNFCEOD_01726 0.0 malL 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HKNFCEOD_01727 1.75e-231 purR2 - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HKNFCEOD_01728 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HKNFCEOD_01729 7e-210 - - - GM - - - NmrA-like family
HKNFCEOD_01730 5.62e-297 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HKNFCEOD_01731 8.04e-183 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HKNFCEOD_01732 1.02e-192 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKNFCEOD_01734 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HKNFCEOD_01735 3.23e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKNFCEOD_01736 2.14e-88 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKNFCEOD_01737 3.31e-282 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKNFCEOD_01738 8.26e-164 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HKNFCEOD_01739 2.42e-209 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HKNFCEOD_01740 9.2e-220 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Nitronate monooxygenase
HKNFCEOD_01741 1.38e-45 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKNFCEOD_01742 3.96e-226 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKNFCEOD_01743 2.44e-99 - - - K - - - Winged helix DNA-binding domain
HKNFCEOD_01744 6.79e-95 - 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HKNFCEOD_01745 0.000324 - - - S - - - CsbD-like
HKNFCEOD_01746 3.33e-205 - - - - - - - -
HKNFCEOD_01747 3.44e-64 - - - - - - - -
HKNFCEOD_01748 3.38e-73 - - - - - - - -
HKNFCEOD_01749 2.11e-69 - - - L ko:K07483 - ko00000 4.5 Transposon and IS
HKNFCEOD_01750 5.04e-174 - - - L - - - Helix-turn-helix domain
HKNFCEOD_01751 8.22e-214 - - - L ko:K07497 - ko00000 hmm pf00665
HKNFCEOD_01752 1.87e-198 - - - L ko:K07497 - ko00000 4.5 Transposon and IS
HKNFCEOD_01757 6.78e-42 - - - - - - - -
HKNFCEOD_01758 3.01e-261 - - - - - - - -
HKNFCEOD_01759 3.79e-283 - - - M - - - Domain of unknown function (DUF5011)
HKNFCEOD_01762 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 TraM recognition site of TraD and TraG
HKNFCEOD_01763 0.0 - - - S - - - domain, Protein
HKNFCEOD_01765 5.31e-136 - - - - - - - -
HKNFCEOD_01766 0.0 - - - S - - - COG0433 Predicted ATPase
HKNFCEOD_01767 1.11e-240 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 cysteine-type peptidase activity
HKNFCEOD_01772 6.98e-05 - - - S - - - Ribbon-helix-helix protein, copG family
HKNFCEOD_01774 9.17e-284 - - - S - - - COG0790 FOG TPR repeat, SEL1 subfamily
HKNFCEOD_01776 0.0 - - - L - - - Protein of unknown function (DUF3991)
HKNFCEOD_01777 8.83e-242 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNFCEOD_01778 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKNFCEOD_01779 8.72e-52 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HKNFCEOD_01780 0.0 - - - S - - - Mga helix-turn-helix domain
HKNFCEOD_01781 3.85e-63 - - - - - - - -
HKNFCEOD_01782 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKNFCEOD_01783 2.09e-143 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HKNFCEOD_01784 2.37e-91 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HKNFCEOD_01785 8.5e-61 - - - S - - - Family of unknown function (DUF5322)
HKNFCEOD_01786 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HKNFCEOD_01787 2.41e-106 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKNFCEOD_01788 5.18e-222 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKNFCEOD_01789 1.05e-125 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKNFCEOD_01790 1.64e-299 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HKNFCEOD_01791 4.42e-228 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HKNFCEOD_01792 1.26e-305 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKNFCEOD_01793 5.32e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HKNFCEOD_01794 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HKNFCEOD_01795 5.67e-200 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKNFCEOD_01796 3.8e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKNFCEOD_01797 2.06e-145 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKNFCEOD_01798 2.03e-189 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Phosphate acetyl/butaryl transferase
HKNFCEOD_01799 2.24e-261 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Acetokinase family
HKNFCEOD_01800 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
HKNFCEOD_01801 9.14e-239 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HKNFCEOD_01802 3.05e-234 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
HKNFCEOD_01803 8.65e-279 bfmBB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
HKNFCEOD_01804 6.1e-227 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKNFCEOD_01805 8.21e-250 pfoS/R - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HKNFCEOD_01806 1e-65 - - - S - - - MazG-like family
HKNFCEOD_01807 0.0 FbpA - - K - - - Fibronectin-binding protein
HKNFCEOD_01808 2.95e-205 - - - S - - - EDD domain protein, DegV family
HKNFCEOD_01809 3.35e-129 - 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HKNFCEOD_01810 3.44e-261 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKNFCEOD_01811 9.02e-277 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKNFCEOD_01812 2.06e-144 hisG 2.4.2.17 - F ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKNFCEOD_01813 4.14e-295 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKNFCEOD_01814 7.58e-134 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HKNFCEOD_01815 1.4e-145 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKNFCEOD_01816 1.26e-156 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKNFCEOD_01817 1.66e-168 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKNFCEOD_01818 1.01e-77 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKNFCEOD_01819 5.01e-69 hisE 3.6.1.31 - E ko:K01523 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 phosphoribosyl-ATP diphosphatase activity
HKNFCEOD_01820 2.07e-261 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKNFCEOD_01821 2.4e-143 - - - C - - - Nitroreductase family
HKNFCEOD_01822 6.04e-94 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_01823 8.72e-64 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_01824 5.52e-243 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Transmembrane secretion effector
HKNFCEOD_01825 1.18e-157 - - - T - - - Transcriptional regulatory protein, C terminal
HKNFCEOD_01826 1.42e-218 kinG - - T - - - Histidine kinase-like ATPases
HKNFCEOD_01827 2.68e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01828 0.0 XK27_05700 - - V ko:K02004,ko:K19084 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 FtsX-like permease family
HKNFCEOD_01829 7.18e-79 - - - - - - - -
HKNFCEOD_01830 3.48e-268 xerS - - L ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HKNFCEOD_01831 7.62e-219 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HKNFCEOD_01832 1.06e-231 - - - K - - - LysR substrate binding domain
HKNFCEOD_01833 2.56e-217 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKNFCEOD_01834 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 Pyruvate formate lyase-like
HKNFCEOD_01835 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKNFCEOD_01836 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKNFCEOD_01837 6.92e-141 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKNFCEOD_01838 5.38e-219 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HKNFCEOD_01839 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKNFCEOD_01840 2.06e-119 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKNFCEOD_01841 1.66e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family. XerC subfamily
HKNFCEOD_01842 2.84e-316 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKNFCEOD_01843 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKNFCEOD_01844 6.33e-187 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HKNFCEOD_01845 5.87e-178 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKNFCEOD_01846 2.53e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKNFCEOD_01847 1.81e-63 - - - K - - - Helix-turn-helix domain
HKNFCEOD_01848 8.61e-317 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HKNFCEOD_01849 1.03e-54 yozE - - S - - - Belongs to the UPF0346 family
HKNFCEOD_01850 3.02e-111 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKNFCEOD_01851 3.18e-147 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HKNFCEOD_01852 1.39e-195 XK27_03630 - - E - - - GDSL-like Lipase/Acylhydrolase
HKNFCEOD_01853 1.4e-189 WQ51_01275 - - S - - - EDD domain protein, DegV family
HKNFCEOD_01854 1.83e-148 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HKNFCEOD_01855 3e-118 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKNFCEOD_01856 2e-242 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKNFCEOD_01857 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01858 2.95e-110 - - - - - - - -
HKNFCEOD_01859 1.77e-282 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKNFCEOD_01860 8.71e-200 ypjC - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKNFCEOD_01861 4.36e-302 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HKNFCEOD_01862 1.2e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKNFCEOD_01863 7.41e-312 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HKNFCEOD_01864 4.93e-303 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HKNFCEOD_01865 2.04e-149 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HKNFCEOD_01866 1.68e-104 - - - M - - - Lysin motif
HKNFCEOD_01867 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HKNFCEOD_01868 1.19e-230 - - - S - - - Helix-turn-helix domain
HKNFCEOD_01869 1.16e-60 fer - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
HKNFCEOD_01870 6.84e-186 - - - G ko:K02746 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_01871 3.48e-114 - - - G ko:K02745 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_01872 2.47e-295 ugl 3.2.1.180 GH88 S ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HKNFCEOD_01873 9.16e-203 - - - S - - - Psort location Cytoplasmic, score
HKNFCEOD_01874 1.1e-179 - - - K - - - Bacterial transcriptional regulator
HKNFCEOD_01875 3.09e-208 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKNFCEOD_01876 1.29e-192 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKNFCEOD_01877 2.71e-152 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 KDPG and KHG aldolase
HKNFCEOD_01878 1.94e-247 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 pfkB family carbohydrate kinase
HKNFCEOD_01879 7.2e-151 alkD - - L - - - DNA alkylation repair enzyme
HKNFCEOD_01880 4.14e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKNFCEOD_01881 0.0 - - - M - - - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKNFCEOD_01882 2.88e-220 ykoT - - M - - - Glycosyl transferase family 2
HKNFCEOD_01883 1.56e-154 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 phosphatase
HKNFCEOD_01884 1.23e-146 - - - S ko:K03975 - ko00000 SNARE-like domain protein
HKNFCEOD_01885 5.92e-314 kinE - - T - - - Histidine kinase
HKNFCEOD_01886 1.14e-161 llrE - - K - - - Transcriptional regulatory protein, C terminal
HKNFCEOD_01887 0.0 - 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HKNFCEOD_01888 0.0 - 2.7.1.199, 2.7.1.208 - G ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HKNFCEOD_01889 1.11e-82 hylB 4.2.2.1 PL8 N ko:K01727 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
HKNFCEOD_01890 0.0 hylB 4.2.2.1 PL8 N ko:K01727 - ko00000,ko01000 Polysaccharide lyase family 8, N terminal alpha-helical domain
HKNFCEOD_01893 0.0 - - - - - - - -
HKNFCEOD_01894 0.0 yvcC - - M - - - Cna protein B-type domain
HKNFCEOD_01895 4.1e-162 - - - M - - - domain protein
HKNFCEOD_01896 1.25e-236 - - - M - - - LPXTG cell wall anchor motif
HKNFCEOD_01897 3.16e-258 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HKNFCEOD_01898 1.53e-160 XK27_12140 - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_01899 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
HKNFCEOD_01900 2.22e-163 - - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HKNFCEOD_01901 6.82e-245 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKNFCEOD_01902 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HKNFCEOD_01903 0.0 prtP 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HKNFCEOD_01904 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HKNFCEOD_01905 1.6e-93 - - - - - - - -
HKNFCEOD_01907 5.82e-197 XK27_08835 - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_01908 2.83e-188 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HKNFCEOD_01909 6.77e-167 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_01910 1.65e-111 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HKNFCEOD_01911 2.82e-105 - - - K - - - Acetyltransferase GNAT Family
HKNFCEOD_01913 4.33e-132 - - - S - - - ECF transporter, substrate-specific component
HKNFCEOD_01914 1.04e-269 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HKNFCEOD_01915 8.79e-199 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 converts alpha-aldose to the beta-anomer
HKNFCEOD_01916 1.74e-131 - - - V ko:K07448 - ko00000,ko02048 Restriction endonuclease
HKNFCEOD_01917 2.74e-204 - - - G - - - Xylose isomerase domain protein TIM barrel
HKNFCEOD_01918 7.23e-66 - - - - - - - -
HKNFCEOD_01919 1.41e-265 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HKNFCEOD_01920 2.21e-265 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HKNFCEOD_01921 2.6e-279 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HKNFCEOD_01922 0.0 poxL 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HKNFCEOD_01923 6.27e-67 ptcB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_01924 7.89e-66 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HKNFCEOD_01925 2.36e-111 - - - - - - - -
HKNFCEOD_01926 0.0 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_01927 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKNFCEOD_01928 2.13e-172 - - - K ko:K03489 - ko00000,ko03000 UTRA
HKNFCEOD_01929 1.68e-103 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HKNFCEOD_01930 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKNFCEOD_01931 6.46e-83 - - - - - - - -
HKNFCEOD_01932 1.1e-224 frvR - - K ko:K02538,ko:K03483,ko:K09685,ko:K18531 - ko00000,ko03000 transcriptional antiterminator
HKNFCEOD_01934 0.0 - - - L - - - DNA helicase
HKNFCEOD_01935 5.66e-193 rlrG - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HKNFCEOD_01936 6.52e-222 ydiA - - P ko:K11041 ko05150,map05150 ko00000,ko00001,ko02042 Voltage-dependent anion channel
HKNFCEOD_01937 1.15e-147 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HKNFCEOD_01939 5.14e-149 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNFCEOD_01940 6.41e-92 - - - K - - - MarR family
HKNFCEOD_01941 0.0 uvrA3 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC
HKNFCEOD_01942 1.47e-244 yghZ - - C ko:K19265 - ko00000,ko01000 Aldo keto reductase family protein
HKNFCEOD_01943 5.86e-187 - - - S - - - hydrolase
HKNFCEOD_01944 3.33e-78 - - - - - - - -
HKNFCEOD_01945 1.99e-16 - - - - - - - -
HKNFCEOD_01946 2.42e-138 - - - S - - - Protein of unknown function (DUF1275)
HKNFCEOD_01947 6.36e-161 gpmB - - G ko:K15640 - ko00000 Phosphoglycerate mutase family
HKNFCEOD_01948 5.93e-196 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HKNFCEOD_01949 3.01e-112 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKNFCEOD_01950 4.39e-213 - - - K - - - LysR substrate binding domain
HKNFCEOD_01951 8.22e-289 - - - EK - - - Aminotransferase, class I
HKNFCEOD_01952 1.97e-235 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKNFCEOD_01953 2.74e-133 ydfK - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HKNFCEOD_01954 5.24e-116 - - - - - - - -
HKNFCEOD_01955 1.67e-239 fruC 2.7.1.202 - GT ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_01956 3.33e-230 - - - S - - - Phage tail protein
HKNFCEOD_01957 1.64e-286 - - - L - - - Phage tail tape measure protein TP901
HKNFCEOD_01958 8.54e-32 - - - - - - - -
HKNFCEOD_01959 1.64e-70 - - - S - - - Phage tail assembly chaperone proteins, TAC
HKNFCEOD_01960 2.21e-141 - - - S - - - Phage tail tube protein
HKNFCEOD_01961 1.02e-80 - - - S - - - Protein of unknown function (DUF806)
HKNFCEOD_01962 6.38e-88 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HKNFCEOD_01963 1.03e-72 - - - S - - - Phage head-tail joining protein
HKNFCEOD_01964 3.58e-46 - - - - - - - -
HKNFCEOD_01965 0.0 - - - S ko:K06904 - ko00000 Phage capsid family
HKNFCEOD_01966 9.37e-255 - - - S - - - Phage portal protein
HKNFCEOD_01968 0.0 - - - S - - - Phage Terminase
HKNFCEOD_01969 6.39e-102 - - - L - - - Phage terminase, small subunit
HKNFCEOD_01970 2.32e-50 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HKNFCEOD_01974 6.91e-74 - - - V - - - HNH nucleases
HKNFCEOD_01975 3.43e-58 - - - L - - - Single-strand binding protein family
HKNFCEOD_01976 8.67e-120 - - - - - - - -
HKNFCEOD_01977 1.92e-208 - - - M - - - Peptidoglycan-binding domain 1 protein
HKNFCEOD_01978 2.59e-97 - - - S - - - NusG domain II
HKNFCEOD_01979 0.0 cydD1 - - CO ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HKNFCEOD_01980 0.0 msbA9 - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HKNFCEOD_01981 3.99e-197 bglG4 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HKNFCEOD_01982 0.0 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKNFCEOD_01983 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKNFCEOD_01984 3.35e-125 - - - K ko:K18939 - ko00000,ko00002,ko03000 Bacterial regulatory proteins, tetR family
HKNFCEOD_01985 6.16e-316 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HKNFCEOD_01986 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HKNFCEOD_01987 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKNFCEOD_01988 3.4e-82 - - - S - - - Coenzyme PQQ synthesis protein D (PqqD)
HKNFCEOD_01989 0.0 - - - S - - - OPT oligopeptide transporter protein
HKNFCEOD_01990 2.06e-236 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKNFCEOD_01991 9.75e-256 ald1 1.4.1.1 - C ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HKNFCEOD_01992 5.9e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
HKNFCEOD_01993 6.89e-73 - - - I - - - ABC-2 family transporter protein
HKNFCEOD_01994 1.17e-82 yugI - - J ko:K07570 - ko00000 general stress protein
HKNFCEOD_01995 2.99e-140 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKNFCEOD_01996 1.57e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HKNFCEOD_01997 2.26e-115 pgpA 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phosphatidylglycerophosphatase A
HKNFCEOD_01998 8.69e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HKNFCEOD_01999 6.43e-146 - - - S - - - Protein of unknown function (DUF1461)
HKNFCEOD_02000 1.34e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKNFCEOD_02001 2.93e-150 yutD - - S - - - Protein of unknown function (DUF1027)
HKNFCEOD_02002 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HKNFCEOD_02003 1.01e-145 - - - S - - - Calcineurin-like phosphoesterase
HKNFCEOD_02004 1.49e-147 yibF - - S - - - overlaps another CDS with the same product name
HKNFCEOD_02005 1.2e-240 yibE - - S - - - overlaps another CDS with the same product name
HKNFCEOD_02006 4.07e-72 - - - - - - - -
HKNFCEOD_02007 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Glycerophosphoryl diester phosphodiesterase family
HKNFCEOD_02008 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HKNFCEOD_02009 5.87e-177 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKNFCEOD_02010 1.06e-163 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HKNFCEOD_02011 0.0 pbp1B 2.4.1.129 GT51 M ko:K03693,ko:K12551 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin binding protein transpeptidase domain
HKNFCEOD_02012 1.23e-231 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HKNFCEOD_02013 3.64e-273 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKNFCEOD_02014 0.0 - - - S - - - peptidoglycan catabolic process
HKNFCEOD_02015 2.72e-27 - - - - - - - -
HKNFCEOD_02016 4.81e-93 - - - S - - - Pfam:Phage_TTP_1
HKNFCEOD_02017 1.87e-38 - - - - - - - -
HKNFCEOD_02018 3.15e-85 - - - S - - - exonuclease activity
HKNFCEOD_02019 2.68e-51 - - - S - - - Phage head-tail joining protein
HKNFCEOD_02020 1.69e-33 - - - S - - - Phage gp6-like head-tail connector protein
HKNFCEOD_02021 4.76e-36 - - - S - - - peptidase activity
HKNFCEOD_02022 8.38e-271 - - - S - - - peptidase activity
HKNFCEOD_02023 2.41e-142 - - - S - - - peptidase activity
HKNFCEOD_02024 1.71e-301 - - - S - - - Phage portal protein
HKNFCEOD_02026 0.0 - - - S - - - Phage Terminase
HKNFCEOD_02027 3.07e-103 - - - S - - - Phage terminase, small subunit
HKNFCEOD_02028 8.74e-86 - - - S - - - HNH endonuclease
HKNFCEOD_02029 2.47e-22 - - - - - - - -
HKNFCEOD_02031 8.61e-62 - - - - - - - -
HKNFCEOD_02032 5.62e-294 - - - - - - - -
HKNFCEOD_02033 3.8e-74 - - - - - - - -
HKNFCEOD_02034 1.35e-212 - 4.1.1.52 - S ko:K22213 - ko00000,ko01000 Amidohydrolase
HKNFCEOD_02035 9.64e-317 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKNFCEOD_02036 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 P-type ATPase
HKNFCEOD_02037 1.77e-74 cadC5 - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HKNFCEOD_02038 0.0 - 3.6.3.6 - P ko:K01535 ko00190,map00190 ko00000,ko00001,ko01000 Cation transporter/ATPase, N-terminus
HKNFCEOD_02039 1.34e-202 lysR5 - - K - - - LysR substrate binding domain
HKNFCEOD_02041 5.5e-42 - - - - - - - -
HKNFCEOD_02042 2.05e-257 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_02043 1.91e-46 - - - S - - - Phospholipase_D-nuclease N-terminal
HKNFCEOD_02044 5.32e-214 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02045 8.89e-169 - - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKNFCEOD_02046 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HKNFCEOD_02047 2.32e-169 - - - - - - - -
HKNFCEOD_02048 5.45e-131 - - - K - - - Bacteriophage CI repressor helix-turn-helix domain
HKNFCEOD_02049 0.0 - - - - - - - -
HKNFCEOD_02050 5.68e-83 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HKNFCEOD_02051 4.66e-44 - - - - - - - -
HKNFCEOD_02052 6.59e-277 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKNFCEOD_02053 2.63e-82 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKNFCEOD_02054 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKNFCEOD_02055 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKNFCEOD_02056 4.87e-187 - - - - - - - -
HKNFCEOD_02057 4.35e-159 - - - S - - - Tetratricopeptide repeat
HKNFCEOD_02058 2.61e-163 - - - - - - - -
HKNFCEOD_02059 9.32e-87 - - - - - - - -
HKNFCEOD_02060 2.28e-57 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HKNFCEOD_02061 9.48e-300 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKNFCEOD_02062 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKNFCEOD_02063 3.42e-202 ybbB - - S - - - Protein of unknown function (DUF1211)
HKNFCEOD_02064 1.15e-111 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKNFCEOD_02065 3.48e-103 ywiB - - S - - - Domain of unknown function (DUF1934)
HKNFCEOD_02066 4.89e-201 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HKNFCEOD_02067 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HKNFCEOD_02068 1.41e-103 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HKNFCEOD_02069 1.44e-235 - - - S - - - DUF218 domain
HKNFCEOD_02070 1.31e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKNFCEOD_02071 4.3e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HKNFCEOD_02072 2.2e-176 - - - S - - - Putative threonine/serine exporter
HKNFCEOD_02073 2.51e-98 - - - S - - - Threonine/Serine exporter, ThrE
HKNFCEOD_02075 2.29e-273 livJ - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
HKNFCEOD_02076 1.04e-191 livH - - U ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HKNFCEOD_02077 1.28e-181 livM - - E ko:K01997,ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid transport system / permease component
HKNFCEOD_02078 3.01e-180 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Branched-chain amino acid ATP-binding cassette transporter
HKNFCEOD_02079 1.16e-159 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_02080 7.59e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HKNFCEOD_02081 1.12e-303 pts14C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_02082 4.1e-152 - - - G - - - Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKNFCEOD_02083 2.9e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKNFCEOD_02084 3.24e-293 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKNFCEOD_02085 3.82e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HKNFCEOD_02086 5.94e-203 p75 - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HKNFCEOD_02089 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HKNFCEOD_02090 9.76e-176 - - - - - - - -
HKNFCEOD_02091 1.96e-154 - - - - - - - -
HKNFCEOD_02092 0.0 uvrB3 3.1.12.1 - KL ko:K07464 - ko00000,ko01000,ko02048 DEAD_2
HKNFCEOD_02093 3.49e-307 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HKNFCEOD_02094 2.22e-110 - - - - - - - -
HKNFCEOD_02095 0.0 strH 3.2.1.52 GH20 G ko:K12373 ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142 ko00000,ko00001,ko00002,ko01000,ko03110 Gram-positive signal peptide protein, YSIRK family
HKNFCEOD_02096 3.05e-247 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HKNFCEOD_02097 5.43e-167 - - - K ko:K03710 - ko00000,ko03000 UTRA
HKNFCEOD_02098 2.32e-280 agaS - - G ko:K02082 - ko00000,ko01000 SIS domain
HKNFCEOD_02099 1.3e-287 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKNFCEOD_02100 0.0 bgaC 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 Glycosyl hydrolases family 35
HKNFCEOD_02101 5.61e-108 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_02102 4.68e-206 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_02103 3.66e-187 - - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKNFCEOD_02104 2.72e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_02105 1.03e-177 lacC 2.7.1.144 - F ko:K00917 ko00052,ko01100,map00052,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HKNFCEOD_02106 3.51e-182 srlD 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 KR domain
HKNFCEOD_02107 3.44e-299 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HKNFCEOD_02108 2.36e-86 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_02109 1.58e-60 - 2.7.1.200 - G ko:K02774 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_02110 4.05e-180 - - - - - - - -
HKNFCEOD_02111 2.96e-284 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HKNFCEOD_02112 2.62e-243 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HKNFCEOD_02113 2.36e-246 - 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HKNFCEOD_02114 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKNFCEOD_02115 2.96e-78 - 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_02116 6.85e-67 - 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HKNFCEOD_02117 2.01e-240 - - - E - - - M42 glutamyl aminopeptidase
HKNFCEOD_02118 0.0 - - - GKT ko:K03491 - ko00000,ko03000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKNFCEOD_02119 2.45e-309 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HKNFCEOD_02120 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKNFCEOD_02121 1.7e-153 - - - S ko:K03824 - ko00000,ko01000 Acetyltransferase (GNAT) family
HKNFCEOD_02123 8.84e-121 - - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HKNFCEOD_02124 1.66e-305 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKNFCEOD_02125 1.94e-135 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HKNFCEOD_02126 5.06e-168 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKNFCEOD_02127 8.83e-108 thiW - - S - - - Thiamine-precursor transporter protein (ThiW)
HKNFCEOD_02128 6.12e-194 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKNFCEOD_02129 6.07e-138 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKNFCEOD_02130 2.12e-187 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HKNFCEOD_02131 0.0 - - - E - - - Amino acid permease
HKNFCEOD_02132 1.16e-45 - - - - - - - -
HKNFCEOD_02133 2.08e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HKNFCEOD_02134 3.66e-85 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKNFCEOD_02135 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HKNFCEOD_02136 4.84e-198 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HKNFCEOD_02137 1.41e-214 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
HKNFCEOD_02138 1.34e-207 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKNFCEOD_02139 3.48e-53 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HKNFCEOD_02140 0.0 pbpC - - M ko:K21467 - ko00000,ko01011 NTF2-like N-terminal transpeptidase domain
HKNFCEOD_02141 1.37e-119 - - - EGP - - - Major Facilitator
HKNFCEOD_02142 3.79e-96 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HKNFCEOD_02143 1.89e-133 - - - - - - - -
HKNFCEOD_02144 8.28e-30 - - - - - - - -
HKNFCEOD_02145 9.97e-83 - - - - - - - -
HKNFCEOD_02146 2.34e-79 - - - - - - - -
HKNFCEOD_02147 0.0 frdC 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 HI0933-like protein
HKNFCEOD_02148 4.69e-250 - - - GKT - - - transcriptional antiterminator
HKNFCEOD_02149 3.38e-66 - 2.7.1.194 - G ko:K02822 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_02150 2.29e-291 - - - S ko:K03475 ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sugar-specific permease component
HKNFCEOD_02151 6.87e-88 - - - - - - - -
HKNFCEOD_02152 6.47e-208 - 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-bisphosphate aldolase class-II
HKNFCEOD_02153 2.61e-148 - - - S - - - Zeta toxin
HKNFCEOD_02154 7.23e-200 - - - K - - - Sugar-specific transcriptional regulator TrmB
HKNFCEOD_02155 3.93e-190 - - - S - - - Sulfite exporter TauE/SafE
HKNFCEOD_02156 2.9e-229 - 4.3.1.12 - E ko:K01750 ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230 ko00000,ko00001,ko01000 Ornithine cyclodeaminase/mu-crystallin family
HKNFCEOD_02157 3.38e-72 - - - S - - - Enterocin A Immunity
HKNFCEOD_02158 3.07e-135 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose acetyltransferase
HKNFCEOD_02162 3.41e-230 ydhF - - S - - - Aldo keto reductase
HKNFCEOD_02163 5.81e-165 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HKNFCEOD_02164 1.56e-275 yqiG - - C - - - Oxidoreductase
HKNFCEOD_02165 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKNFCEOD_02166 2.2e-173 - - - - - - - -
HKNFCEOD_02167 5.81e-22 - - - - - - - -
HKNFCEOD_02168 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKNFCEOD_02169 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HKNFCEOD_02170 4.65e-72 - - - - - - - -
HKNFCEOD_02171 5.15e-305 - - - EGP - - - Major Facilitator Superfamily
HKNFCEOD_02172 0.0 sufI - - Q - - - Multicopper oxidase
HKNFCEOD_02173 8.86e-35 - - - - - - - -
HKNFCEOD_02174 2.22e-144 - - - P - - - Cation efflux family
HKNFCEOD_02175 1.23e-69 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HKNFCEOD_02176 9.59e-101 usp5 - - T - - - universal stress protein
HKNFCEOD_02177 3.45e-144 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HKNFCEOD_02178 1.72e-213 - - - EG - - - EamA-like transporter family
HKNFCEOD_02179 6.71e-34 - - - - - - - -
HKNFCEOD_02180 4.98e-112 - - - - - - - -
HKNFCEOD_02181 6.98e-53 - - - - - - - -
HKNFCEOD_02182 1.79e-243 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HKNFCEOD_02183 2.74e-302 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HKNFCEOD_02184 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HKNFCEOD_02185 5.88e-232 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HKNFCEOD_02186 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKNFCEOD_02187 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKNFCEOD_02188 6.43e-66 - - - - - - - -
HKNFCEOD_02189 1.12e-82 - - - S - - - Protein of unknown function (DUF1093)
HKNFCEOD_02190 3.11e-274 - - - S - - - Membrane
HKNFCEOD_02191 6.56e-181 - - - - - - - -
HKNFCEOD_02192 8.25e-22 - - - G - - - COG COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HKNFCEOD_02193 3.12e-78 - - - G ko:K17467 ko00030,ko01120,ko02060,map00030,map01120,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKNFCEOD_02194 8.7e-233 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HKNFCEOD_02195 1.5e-201 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Xylulose kinase
HKNFCEOD_02196 4.54e-205 XK27_10120 - - K - - - S-adenosyl-l-methionine hydroxide adenosyltransferase
HKNFCEOD_02197 1.05e-127 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HKNFCEOD_02198 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_02199 3.99e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HKNFCEOD_02200 0.0 ebgA 3.2.1.23 - G ko:K01190,ko:K12111 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HKNFCEOD_02201 0.0 - - - E - - - Amino Acid
HKNFCEOD_02202 5.29e-305 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HKNFCEOD_02203 3.75e-182 - - - K - - - helix_turn_helix, arabinose operon control protein
HKNFCEOD_02204 2.36e-167 - - - E - - - lipolytic protein G-D-S-L family
HKNFCEOD_02205 4.14e-91 - - - P ko:K04758 - ko00000,ko02000 FeoA
HKNFCEOD_02206 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HKNFCEOD_02207 6.28e-25 - - - S - - - Virus attachment protein p12 family
HKNFCEOD_02208 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HKNFCEOD_02209 8.15e-77 - - - - - - - -
HKNFCEOD_02210 1.86e-292 - 3.2.1.51 GH29 G ko:K01206 ko00511,map00511 ko00000,ko00001,ko01000,ko04147 Alpha-L-fucosidase
HKNFCEOD_02211 0.0 - - - G - - - MFS/sugar transport protein
HKNFCEOD_02212 6.13e-100 - - - S - - - function, without similarity to other proteins
HKNFCEOD_02213 1.71e-87 - - - - - - - -
HKNFCEOD_02214 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_02215 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HKNFCEOD_02216 4.9e-202 - - - S - - - Calcineurin-like phosphoesterase
HKNFCEOD_02219 5.89e-224 int3 - - L - - - Belongs to the 'phage' integrase family
HKNFCEOD_02220 6.44e-95 - - - - - - - -
HKNFCEOD_02221 8.34e-155 - - - S - - - sequence-specific DNA binding
HKNFCEOD_02222 2e-48 - - - S - - - sequence-specific DNA binding
HKNFCEOD_02225 3.93e-08 - - - S - - - Domain of unknown function (DUF771)
HKNFCEOD_02228 3.23e-103 - - - S - - - Siphovirus Gp157
HKNFCEOD_02229 1.75e-166 - - - S - - - AAA domain
HKNFCEOD_02230 8.99e-133 - - - S - - - Protein of unknown function (DUF669)
HKNFCEOD_02231 1.15e-143 - - - S - - - calcium ion binding
HKNFCEOD_02232 5.68e-297 - - - S - - - DNA helicase activity
HKNFCEOD_02234 2.86e-74 rusA - - L - - - Endodeoxyribonuclease RusA
HKNFCEOD_02235 9.09e-23 - - - - - - - -
HKNFCEOD_02236 4.43e-158 - - - S - - - DNA methylation
HKNFCEOD_02237 1.7e-116 - - - L - - - Belongs to the 'phage' integrase family
HKNFCEOD_02240 1.34e-41 - - - - - - - -
HKNFCEOD_02244 1.7e-42 - - - - - - - -
HKNFCEOD_02245 1.28e-78 - - - Q - - - DNA (cytosine-5-)-methyltransferase activity
HKNFCEOD_02249 2.58e-130 - 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HKNFCEOD_02250 3.89e-147 - 1.1.1.140 - IQ ko:K00068 ko00051,map00051 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HKNFCEOD_02251 8.16e-79 - - - K - - - DeoR C terminal sensor domain
HKNFCEOD_02252 4.73e-125 - 5.3.1.27 - M ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HKNFCEOD_02253 8.02e-144 - 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Orotidine 5'-phosphate decarboxylase / HUMPS family
HKNFCEOD_02254 2.38e-173 - - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HKNFCEOD_02255 9.46e-159 - - - S - - - Haloacid dehalogenase-like hydrolase
HKNFCEOD_02257 1.21e-69 - - - - - - - -
HKNFCEOD_02258 2.15e-199 levD - - G ko:K02771 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko02000 PTS system mannose/fructose/sorbose family IID component
HKNFCEOD_02259 5.53e-196 levC - - M ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_02260 2.66e-117 - 2.7.1.191 - G ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HKNFCEOD_02261 1.17e-95 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HKNFCEOD_02262 0.0 - - - K - - - Sigma-54 interaction domain
HKNFCEOD_02263 1.32e-63 - - - - - - - -
HKNFCEOD_02264 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HKNFCEOD_02265 1.14e-276 - - - V - - - Beta-lactamase
HKNFCEOD_02266 2.51e-195 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKNFCEOD_02267 1.11e-280 - - - V - - - Beta-lactamase
HKNFCEOD_02268 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKNFCEOD_02269 1.62e-161 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HKNFCEOD_02270 7.45e-280 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKNFCEOD_02271 9.25e-177 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKNFCEOD_02272 0.0 yuxL 3.4.19.1 - E ko:K01303 - ko00000,ko01000,ko01002 Prolyl oligopeptidase family
HKNFCEOD_02274 4.03e-146 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HKNFCEOD_02275 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKNFCEOD_02276 1.87e-41 - - - - - - - -
HKNFCEOD_02278 2.41e-13 - - - - - - - -
HKNFCEOD_02279 1.48e-67 - - - L - - - Initiator Replication protein
HKNFCEOD_02287 6.28e-197 p40 - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 CHAP domain
HKNFCEOD_02288 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKNFCEOD_02289 1.76e-165 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_02290 2.79e-126 - - - K - - - transcriptional regulator
HKNFCEOD_02291 4.35e-197 - - - G - - - Sucrose-6F-phosphate phosphohydrolase
HKNFCEOD_02294 0.0 ybfG - - M - - - peptidoglycan-binding domain-containing protein
HKNFCEOD_02295 4.32e-136 - - - S ko:K07090 - ko00000 membrane transporter protein
HKNFCEOD_02297 5.68e-110 guaD - - FJ - - - MafB19-like deaminase
HKNFCEOD_02298 1.48e-218 ysjB - - S ko:K03810 - ko00000 Oxidoreductase family, NAD-binding Rossmann fold
HKNFCEOD_02299 1.87e-292 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferases group 1
HKNFCEOD_02300 5.49e-71 - - - S - - - Pfam Transposase IS66
HKNFCEOD_02301 6.61e-195 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HKNFCEOD_02303 2.12e-63 ycnE - - S - - - Antibiotic biosynthesis monooxygenase
HKNFCEOD_02304 5.83e-177 - - - S - - - Domain of unknown function DUF1829
HKNFCEOD_02305 7.39e-253 - - - S - - - peptidoglycan catabolic process
HKNFCEOD_02308 2.04e-78 - - - - - - - -
HKNFCEOD_02310 2.93e-51 - - - - - - - -
HKNFCEOD_02311 1.14e-195 - - - S - - - cellulase activity
HKNFCEOD_02312 0.0 - - - - - - - -
HKNFCEOD_02314 2.56e-89 - - - K - - - Cro/C1-type HTH DNA-binding domain
HKNFCEOD_02315 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HKNFCEOD_02317 1.2e-60 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
HKNFCEOD_02318 1.23e-57 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HKNFCEOD_02319 1.36e-134 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_02320 2.93e-143 - - - S - - - Protein of unknown function C-terminus (DUF2399)
HKNFCEOD_02321 1.1e-62 - - - S - - - Protein of unknown function (DUF2568)
HKNFCEOD_02322 1.41e-84 - - - K - - - helix_turn_helix, mercury resistance
HKNFCEOD_02323 2.98e-272 - - - - - - - -
HKNFCEOD_02324 1.63e-201 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02325 1.17e-169 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 type transporter
HKNFCEOD_02326 2.43e-264 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKNFCEOD_02327 2.07e-135 desR - - K ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, Lux Regulon
HKNFCEOD_02328 3.99e-197 degV - - S - - - Uncharacterised protein, DegV family COG1307
HKNFCEOD_02329 4.14e-113 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_02330 1.65e-211 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_02331 1.5e-142 - - - K - - - Psort location Cytoplasmic, score
HKNFCEOD_02332 2.25e-156 gst 2.5.1.18 - O ko:K00799 ko00480,ko00980,ko00982,ko00983,ko01524,ko05200,ko05204,ko05225,ko05418,map00480,map00980,map00982,map00983,map01524,map05200,map05204,map05225,map05418 ko00000,ko00001,ko01000,ko02000 Glutathione S-transferase, C-terminal domain
HKNFCEOD_02333 1.94e-54 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HKNFCEOD_02334 2.72e-149 - - - GM - - - NAD(P)H-binding
HKNFCEOD_02335 1.07e-72 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HKNFCEOD_02336 1.11e-101 yphH - - S - - - Cupin domain
HKNFCEOD_02337 1.71e-206 - - - K - - - Transcriptional regulator
HKNFCEOD_02338 1.8e-142 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_02339 1.17e-217 bcrA - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKNFCEOD_02340 2.69e-156 - - - T - - - Transcriptional regulatory protein, C terminal
HKNFCEOD_02341 3.55e-202 - - - T - - - GHKL domain
HKNFCEOD_02342 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HKNFCEOD_02343 8.16e-203 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Histidinol phosphatase and related hydrolases of the PHP family
HKNFCEOD_02344 2.05e-173 - - - F - - - deoxynucleoside kinase
HKNFCEOD_02345 2.93e-178 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HKNFCEOD_02346 1.66e-218 - - - IQ - - - NAD dependent epimerase/dehydratase family
HKNFCEOD_02347 2.82e-197 mrsA1 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKNFCEOD_02348 1.89e-157 - - - G - - - alpha-ribazole phosphatase activity
HKNFCEOD_02349 4.62e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKNFCEOD_02350 1.02e-158 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HKNFCEOD_02351 5.99e-143 yktB - - S - - - Belongs to the UPF0637 family
HKNFCEOD_02352 1.13e-98 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HKNFCEOD_02353 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HKNFCEOD_02354 1.66e-306 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HKNFCEOD_02355 1.65e-52 - - - - - - - -
HKNFCEOD_02356 6.73e-107 uspA - - T - - - universal stress protein
HKNFCEOD_02357 2.7e-200 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_02358 2.13e-149 yhfA - - S - - - HAD hydrolase, family IA, variant 3
HKNFCEOD_02359 3.03e-231 - - - S - - - Protein of unknown function (DUF2785)
HKNFCEOD_02360 9.85e-88 - - - S - - - Protein of unknown function (DUF1694)
HKNFCEOD_02361 6.72e-31 - - - - - - - -
HKNFCEOD_02362 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HKNFCEOD_02363 4.94e-103 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HKNFCEOD_02364 4.87e-280 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKNFCEOD_02365 5.51e-243 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HKNFCEOD_02366 3.41e-183 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HKNFCEOD_02367 1.31e-149 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HKNFCEOD_02368 2.43e-242 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKNFCEOD_02369 8.04e-192 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKNFCEOD_02371 2.67e-186 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HKNFCEOD_02372 3.19e-284 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HKNFCEOD_02373 4.19e-65 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HKNFCEOD_02374 1.41e-285 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HKNFCEOD_02375 8.37e-42 - - - S - - - Protein of unknown function (DUF2969)
HKNFCEOD_02376 1.14e-72 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HKNFCEOD_02377 1.37e-26 - - - S - - - DNA-directed RNA polymerase subunit beta
HKNFCEOD_02378 4.12e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HKNFCEOD_02379 8.38e-42 - - - S - - - Protein of unknown function (DUF1146)
HKNFCEOD_02380 1.88e-91 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HKNFCEOD_02381 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKNFCEOD_02382 1.92e-211 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKNFCEOD_02383 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKNFCEOD_02384 3.93e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKNFCEOD_02385 3.59e-80 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKNFCEOD_02386 2.57e-37 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKNFCEOD_02387 1.23e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HKNFCEOD_02388 3.05e-145 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKNFCEOD_02389 1.57e-298 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKNFCEOD_02390 1.4e-237 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKNFCEOD_02391 6.65e-196 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKNFCEOD_02392 8.62e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKNFCEOD_02393 7.61e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HKNFCEOD_02394 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HKNFCEOD_02395 1.45e-248 ampC - - V - - - Beta-lactamase
HKNFCEOD_02396 1.07e-207 catE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HKNFCEOD_02397 7.15e-179 - - - S - - - NADPH-dependent FMN reductase
HKNFCEOD_02398 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HKNFCEOD_02399 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_02400 6.41e-155 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_02401 4.1e-163 pgm7 - - G - - - Phosphoglycerate mutase family
HKNFCEOD_02404 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKNFCEOD_02405 4.36e-136 - - - S - - - Protein of unknown function (DUF1211)
HKNFCEOD_02406 3.11e-271 yttB - - EGP - - - Major Facilitator
HKNFCEOD_02407 1.53e-19 - - - - - - - -
HKNFCEOD_02408 4.26e-103 tspO - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 TspO/MBR family
HKNFCEOD_02409 0.0 ybeC - - E - - - amino acid
HKNFCEOD_02411 8.97e-294 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKNFCEOD_02412 9.32e-252 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HKNFCEOD_02413 1.58e-220 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKNFCEOD_02415 4.48e-277 araT - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HKNFCEOD_02416 1.52e-57 ykuJ - - S - - - Protein of unknown function (DUF1797)
HKNFCEOD_02417 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKNFCEOD_02418 8.92e-105 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HKNFCEOD_02419 4.65e-277 - - - - - - - -
HKNFCEOD_02420 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKNFCEOD_02421 1.01e-165 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKNFCEOD_02422 4.06e-153 yleF - - K - - - Helix-turn-helix domain, rpiR family
HKNFCEOD_02423 5.32e-117 - - - K - - - Transcriptional regulator C-terminal region
HKNFCEOD_02424 1.02e-144 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_02425 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HKNFCEOD_02426 7.93e-99 - - - O - - - OsmC-like protein
HKNFCEOD_02427 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HKNFCEOD_02428 2.73e-147 ylbE - - GM - - - NAD(P)H-binding
HKNFCEOD_02430 6.7e-203 - - - S - - - Aldo/keto reductase family
HKNFCEOD_02431 3.61e-316 yifK - - E ko:K03293 - ko00000 Amino acid permease
HKNFCEOD_02432 0.0 - - - S - - - Protein of unknown function (DUF3800)
HKNFCEOD_02433 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HKNFCEOD_02435 5.79e-157 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HKNFCEOD_02436 1.75e-45 - - - - - - - -
HKNFCEOD_02437 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HKNFCEOD_02438 3.26e-151 - - - S - - - WxL domain surface cell wall-binding
HKNFCEOD_02439 4.74e-223 - - - S - - - Cell surface protein
HKNFCEOD_02440 7.26e-58 - - - - - - - -
HKNFCEOD_02441 2.48e-239 - - - S - - - Leucine-rich repeat (LRR) protein
HKNFCEOD_02442 8.85e-76 - - - - - - - -
HKNFCEOD_02443 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HKNFCEOD_02444 1.7e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKNFCEOD_02445 2.01e-118 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKNFCEOD_02446 1.94e-70 XK27_08430 - - S - - - Staphylococcal protein of unknown function (DUF960)
HKNFCEOD_02447 1.91e-195 hutG 3.5.3.8 - E ko:K01479 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 N-formylglutamate amidohydrolase
HKNFCEOD_02448 6.49e-123 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_02449 1.26e-142 - - - S - - - Flavodoxin-like fold
HKNFCEOD_02451 2.55e-105 - - - K - - - Acetyltransferase (GNAT) domain
HKNFCEOD_02452 1.72e-64 - - - - - - - -
HKNFCEOD_02453 6.1e-27 - - - - - - - -
HKNFCEOD_02455 5.4e-69 - - - S - - - Phage head-tail joining protein
HKNFCEOD_02456 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4
HKNFCEOD_02457 7.97e-188 - - - L - - - Bifunctional DNA primase/polymerase, N-terminal
HKNFCEOD_02458 1.28e-33 - - - - - - - -
HKNFCEOD_02460 2.02e-31 - - - - - - - -
HKNFCEOD_02461 3.16e-25 - - - - - - - -
HKNFCEOD_02462 2.42e-32 - - - - - - - -
HKNFCEOD_02465 1.76e-280 sip - - L - - - Belongs to the 'phage' integrase family
HKNFCEOD_02466 7.05e-219 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HKNFCEOD_02467 2.35e-286 yagE - - E - - - Amino acid permease
HKNFCEOD_02469 1.28e-135 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_02470 8.73e-206 - - - - - - - -
HKNFCEOD_02471 7.33e-272 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-type transport system involved in multi-copper enzyme maturation permease component
HKNFCEOD_02472 3.93e-161 - - - - - - - -
HKNFCEOD_02474 8.58e-139 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_02475 0.0 - - - EGP - - - Major Facilitator
HKNFCEOD_02476 3.74e-265 - - - - - - - -
HKNFCEOD_02477 8.82e-207 CcmA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02478 6.81e-86 ytrA - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HKNFCEOD_02479 2.05e-277 ysdA - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_02480 9.96e-212 ysdB - - S ko:K01990 - ko00000,ko00002,ko02000 abc transporter atp-binding protein
HKNFCEOD_02481 1.92e-283 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKNFCEOD_02482 2.67e-225 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HKNFCEOD_02483 9.76e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HKNFCEOD_02484 6.08e-256 - - - S - - - Calcineurin-like phosphoesterase
HKNFCEOD_02485 1.31e-47 - - - L ko:K07485 - ko00000 Transposase
HKNFCEOD_02487 2.37e-91 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
HKNFCEOD_02488 5.11e-93 yqeB - - S - - - Pyrimidine dimer DNA glycosylase
HKNFCEOD_02489 7.14e-193 bla1 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase
HKNFCEOD_02490 6.07e-108 - - - - - - - -
HKNFCEOD_02491 1.23e-228 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HKNFCEOD_02492 1.22e-181 - - - G ko:K02795 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HKNFCEOD_02493 1.26e-109 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNFCEOD_02494 6.33e-275 - - - EGP - - - Major Facilitator Superfamily
HKNFCEOD_02495 6.01e-215 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKNFCEOD_02496 2.74e-206 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HKNFCEOD_02497 2.2e-222 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HKNFCEOD_02498 1.52e-24 - - - - - - - -
HKNFCEOD_02500 5.52e-286 int3 - - L - - - Belongs to the 'phage' integrase family
HKNFCEOD_02504 6.84e-183 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HKNFCEOD_02505 1.1e-134 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HKNFCEOD_02506 1.92e-123 - - - - - - - -
HKNFCEOD_02507 4.61e-97 yjcF - - S - - - Acetyltransferase (GNAT) domain
HKNFCEOD_02508 1.19e-261 yueF - - S - - - AI-2E family transporter
HKNFCEOD_02509 4.82e-310 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
HKNFCEOD_02510 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKNFCEOD_02512 3.36e-61 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
HKNFCEOD_02513 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HKNFCEOD_02514 9.5e-39 - - - - - - - -
HKNFCEOD_02515 1.02e-51 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HKNFCEOD_02516 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKNFCEOD_02517 0.0 iolT - - EGP ko:K06609 - ko00000,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HKNFCEOD_02518 4.51e-134 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HKNFCEOD_02519 2.66e-102 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKNFCEOD_02520 3.51e-273 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKNFCEOD_02521 5.45e-171 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HKNFCEOD_02522 2.43e-54 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKNFCEOD_02523 3.42e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKNFCEOD_02524 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKNFCEOD_02525 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKNFCEOD_02526 9.82e-235 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HKNFCEOD_02527 9.63e-130 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKNFCEOD_02528 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HKNFCEOD_02529 4.31e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HKNFCEOD_02530 1.17e-100 copR - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HKNFCEOD_02531 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5 - P ko:K01533,ko:K01534 - ko00000,ko01000 P-type ATPase
HKNFCEOD_02532 4.42e-141 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKNFCEOD_02533 9.93e-266 - - - T ko:K19168 - ko00000,ko02048 His Kinase A (phosphoacceptor) domain
HKNFCEOD_02534 1.57e-159 rrp1 - - K ko:K02483 - ko00000,ko02022 response regulator
HKNFCEOD_02535 1.14e-177 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02536 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HKNFCEOD_02537 5.33e-119 traP 1.14.99.57, 6.2.1.3 - S ko:K01897,ko:K21481 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 heme oxygenase (decyclizing) activity
HKNFCEOD_02538 3.28e-176 yhfI - - S - - - Metallo-beta-lactamase superfamily
HKNFCEOD_02539 1.13e-89 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKNFCEOD_02540 1.44e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKNFCEOD_02541 0.0 glpQ4 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 phosphodiesterase
HKNFCEOD_02542 3.67e-227 pyrD 1.3.5.2, 1.3.98.1 - F ko:K00226,ko:K00254 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dihydroorotate to orotate
HKNFCEOD_02543 1.16e-31 - - - - - - - -
HKNFCEOD_02544 1.97e-88 - - - - - - - -
HKNFCEOD_02546 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HKNFCEOD_02547 3.31e-98 argR1 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HKNFCEOD_02548 2.61e-198 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HKNFCEOD_02549 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HKNFCEOD_02550 1.03e-72 - - - S - - - Control of competence regulator ComK, YlbF/YmcA
HKNFCEOD_02551 8.42e-232 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNFCEOD_02552 5.26e-205 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKNFCEOD_02553 5.77e-81 - - - S - - - YtxH-like protein
HKNFCEOD_02554 1.67e-99 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HKNFCEOD_02555 6.87e-172 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HKNFCEOD_02556 3.95e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02557 4.51e-189 ytmP - - M - - - Choline/ethanolamine kinase
HKNFCEOD_02558 8.13e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKNFCEOD_02559 1.66e-05 - - - S - - - Small secreted protein
HKNFCEOD_02560 5.32e-73 ytpP - - CO - - - Thioredoxin
HKNFCEOD_02561 3.17e-149 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKNFCEOD_02562 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HKNFCEOD_02563 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HKNFCEOD_02564 4.22e-154 ybhL - - S ko:K06890 - ko00000 Inhibitor of apoptosis-promoting Bax1
HKNFCEOD_02565 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKNFCEOD_02566 3.2e-206 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKNFCEOD_02567 1.1e-129 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKNFCEOD_02568 2.06e-103 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKNFCEOD_02569 9.28e-317 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HKNFCEOD_02570 2.02e-219 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HKNFCEOD_02571 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKNFCEOD_02572 1.04e-133 yrgI 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Histidine phosphatase superfamily (branch 1)
HKNFCEOD_02573 5.3e-70 - - - - - - - -
HKNFCEOD_02574 2.7e-166 - - - S - - - SseB protein N-terminal domain
HKNFCEOD_02575 7.46e-101 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKNFCEOD_02576 1.13e-36 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HKNFCEOD_02577 1.02e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKNFCEOD_02578 8.27e-130 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HKNFCEOD_02579 4.31e-231 - - - C - - - Alcohol dehydrogenase GroES-like domain
HKNFCEOD_02580 2.14e-157 mhqD - - S ko:K06999 - ko00000 Dienelactone hydrolase family
HKNFCEOD_02581 1.93e-243 mhqA_2 - - E ko:K15975 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKNFCEOD_02582 1.95e-220 ykcA - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKNFCEOD_02583 6.63e-127 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HKNFCEOD_02584 2.77e-258 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HKNFCEOD_02585 3.95e-65 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HKNFCEOD_02586 2.72e-157 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKNFCEOD_02587 3.21e-142 yqeK - - H - - - Hydrolase, HD family
HKNFCEOD_02588 1.18e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKNFCEOD_02589 8.39e-179 yccK - - Q - - - ubiE/COQ5 methyltransferase family
HKNFCEOD_02590 9.63e-270 ylbM - - S - - - Belongs to the UPF0348 family
HKNFCEOD_02591 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HKNFCEOD_02592 2.43e-53 - - - S - - - Psort location Cytoplasmic, score
HKNFCEOD_02593 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKNFCEOD_02594 1.01e-157 csrR - - K - - - response regulator
HKNFCEOD_02595 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKNFCEOD_02596 5.91e-140 ywdE - - K ko:K20375 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix XRE-family like proteins
HKNFCEOD_02597 0.0 fnq20 - - S - - - FAD-NAD(P)-binding
HKNFCEOD_02598 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HKNFCEOD_02599 5.08e-149 - - - - - - - -
HKNFCEOD_02600 3.62e-288 - - - S ko:K06872 - ko00000 TPM domain
HKNFCEOD_02601 2.92e-176 yunE - - S ko:K07090 - ko00000 Sulfite exporter TauE/SafE
HKNFCEOD_02602 6.45e-74 ywjH - - S - - - Protein of unknown function (DUF1634)
HKNFCEOD_02603 1.56e-93 - - - - - - - -
HKNFCEOD_02605 8.43e-198 pi346 - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HKNFCEOD_02606 7.76e-181 - - - L - - - Helix-turn-helix domain
HKNFCEOD_02612 1.66e-59 - - - S - - - Domain of unknown function (DUF1883)
HKNFCEOD_02614 2.05e-100 - - - S - - - ORF6N domain
HKNFCEOD_02615 1.16e-201 ps305 - - S - - - Protein of unknown function (Hypoth_ymh)
HKNFCEOD_02618 1.51e-80 - - - K - - - Helix-turn-helix XRE-family like proteins
HKNFCEOD_02619 1.65e-25 - - - E - - - Zn peptidase
HKNFCEOD_02621 3.81e-73 - - - - - - - -
HKNFCEOD_02623 3.28e-183 - - - S - - - CAAX protease self-immunity
HKNFCEOD_02627 1.62e-12 - - - - - - - -
HKNFCEOD_02630 3.08e-169 plnD - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HKNFCEOD_02631 8.04e-166 - 2.7.13.3 - T ko:K02476,ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
HKNFCEOD_02632 2.39e-98 - - - L - - - Initiator Replication protein
HKNFCEOD_02633 2.46e-38 - - - - - - - -
HKNFCEOD_02634 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
HKNFCEOD_02636 8.95e-109 hsdS 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 type I restriction modification DNA specificity domain protein
HKNFCEOD_02638 1.55e-310 - - - S - - - cellulase activity
HKNFCEOD_02639 1.32e-42 - - - - - - - -
HKNFCEOD_02641 3.03e-83 - - - - - - - -
HKNFCEOD_02643 8.39e-65 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HKNFCEOD_02644 2.79e-286 - - - M - - - Glycosyl hydrolases family 25
HKNFCEOD_02647 3.11e-17 - - - E - - - Preprotein translocase subunit SecB
HKNFCEOD_02648 1.07e-90 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
HKNFCEOD_02649 2.04e-65 - - - S - - - Glycosyltransferase family 28 C-terminal domain
HKNFCEOD_02650 5.66e-92 - - - M - - - Glycosyl transferases group 1
HKNFCEOD_02652 4.31e-79 - - GT2 S ko:K12997 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase family 2
HKNFCEOD_02653 2.97e-30 - - - M - - - Glycosyl transferases group 1
HKNFCEOD_02654 2.48e-64 - - - M - - - Glycosyltransferase like family 2
HKNFCEOD_02655 7.26e-208 lacT - - K ko:K02531 - ko00000,ko03000 PRD domain
HKNFCEOD_02656 0.0 lacE 2.7.1.207 - G ko:K02787,ko:K02788 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase system, EIIC
HKNFCEOD_02657 0.0 lacG 3.2.1.21, 3.2.1.85, 3.2.1.86 GT1 G ko:K01220,ko:K01223,ko:K05350 ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKNFCEOD_02658 2.65e-67 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 - G ko:K02759,ko:K02786 ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIA subunit
HKNFCEOD_02659 1.76e-132 - - - - - - - -
HKNFCEOD_02661 4.98e-68 - - - - - - - -
HKNFCEOD_02662 1.02e-144 - - - S - - - Membrane
HKNFCEOD_02663 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HKNFCEOD_02665 2.96e-72 - - - - - - - -
HKNFCEOD_02666 3.2e-98 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HKNFCEOD_02667 2.09e-26 - - - S - - - Glycosyltransferase like family 2
HKNFCEOD_02668 5.53e-70 - - - S - - - Hexapeptide repeat of succinyl-transferase
HKNFCEOD_02669 1.39e-56 cps2J - - S - - - Polysaccharide biosynthesis protein
HKNFCEOD_02670 1.13e-287 yknV - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HKNFCEOD_02671 2.74e-287 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKNFCEOD_02672 1.19e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKNFCEOD_02679 4.32e-105 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HKNFCEOD_02680 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKNFCEOD_02681 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNFCEOD_02682 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNFCEOD_02683 3.63e-47 - 3.4.23.43 - - ko:K02236 - ko00000,ko00002,ko01000,ko02044 -
HKNFCEOD_02684 0.0 - - - M - - - domain protein
HKNFCEOD_02685 1.11e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKNFCEOD_02686 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKNFCEOD_02687 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKNFCEOD_02688 2.39e-255 - - - K - - - WYL domain
HKNFCEOD_02689 6.83e-138 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 C-terminal domain of 1-Cys peroxiredoxin
HKNFCEOD_02690 3.63e-90 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HKNFCEOD_02691 4.46e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HKNFCEOD_02692 4.68e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKNFCEOD_02693 1.98e-140 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HKNFCEOD_02694 1.02e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKNFCEOD_02695 7.23e-201 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKNFCEOD_02696 5.26e-63 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKNFCEOD_02697 4.5e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKNFCEOD_02698 6.88e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKNFCEOD_02699 1.38e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKNFCEOD_02700 3.55e-33 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HKNFCEOD_02701 5.93e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKNFCEOD_02702 1.73e-77 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKNFCEOD_02703 4.1e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKNFCEOD_02704 8.67e-124 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKNFCEOD_02705 1.32e-88 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKNFCEOD_02706 2.61e-123 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKNFCEOD_02707 1.62e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKNFCEOD_02708 5.74e-109 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKNFCEOD_02709 2.6e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HKNFCEOD_02710 4.07e-92 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HKNFCEOD_02711 5.76e-303 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKNFCEOD_02712 5.26e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKNFCEOD_02713 4.15e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKNFCEOD_02714 6.38e-20 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HKNFCEOD_02715 5.37e-76 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKNFCEOD_02716 3.82e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKNFCEOD_02717 1.26e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKNFCEOD_02718 5.46e-81 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HKNFCEOD_02719 8.3e-150 - - - - - - - -
HKNFCEOD_02720 7.77e-196 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKNFCEOD_02721 1.92e-202 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKNFCEOD_02722 1.13e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKNFCEOD_02723 1.39e-178 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKNFCEOD_02724 3.78e-170 tipA - - K - - - TipAS antibiotic-recognition domain
HKNFCEOD_02725 1.5e-44 - - - - - - - -
HKNFCEOD_02726 3.01e-163 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_02727 1.06e-237 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKNFCEOD_02728 2.95e-140 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_02729 2.98e-104 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKNFCEOD_02730 8.98e-86 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HKNFCEOD_02731 2.42e-70 - - - - - - - -
HKNFCEOD_02732 8.78e-144 - - - - - - - -
HKNFCEOD_02733 1.28e-12 - - - S - - - Protein of unknown function (DUF2785)
HKNFCEOD_02734 1.6e-121 - - - S - - - Protein of unknown function (DUF2785)
HKNFCEOD_02735 2.47e-169 - - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02736 3.49e-172 XK27_06945 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_02737 2.65e-173 XK27_06950 - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HKNFCEOD_02738 3.41e-191 ssuC - - U ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_02739 1.17e-154 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HKNFCEOD_02740 1.06e-296 - - - I - - - Acyltransferase family
HKNFCEOD_02741 0.0 - 6.2.1.48 - IQ ko:K02182 - ko00000,ko01000 AMP-binding enzyme C-terminal domain
HKNFCEOD_02742 5.18e-224 ssuA - - P ko:K02051,ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 NMT1-like family
HKNFCEOD_02743 3.27e-187 ptxC - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_02744 2.46e-174 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HKNFCEOD_02745 1.49e-178 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKNFCEOD_02746 1.99e-212 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HKNFCEOD_02747 1.08e-282 - - - P - - - Cation transporter/ATPase, N-terminus
HKNFCEOD_02748 2.14e-280 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKNFCEOD_02751 7.54e-90 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNFCEOD_02752 3.56e-68 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKNFCEOD_02755 1.29e-95 - - - - - - - -
HKNFCEOD_02756 2.1e-27 - - - - - - - -
HKNFCEOD_02757 1.71e-210 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKNFCEOD_02758 0.0 - - - M - - - domain protein
HKNFCEOD_02759 2.87e-101 - - - - - - - -
HKNFCEOD_02760 6.65e-145 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HKNFCEOD_02761 1.15e-151 - - - GM - - - NmrA-like family
HKNFCEOD_02762 2.26e-213 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKNFCEOD_02763 6.85e-55 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKNFCEOD_02764 0.0 aldA 1.2.1.21, 1.2.1.22 - C ko:K07248 ko00620,ko00630,ko01120,map00620,map00630,map01120 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family
HKNFCEOD_02765 3.38e-170 - 3.6.3.35 - P ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HKNFCEOD_02766 5.63e-183 mtsB - - U ko:K19972,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HKNFCEOD_02767 1.89e-225 mntA - - P ko:K19975,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HKNFCEOD_02768 6.97e-133 - - - S - - - Protein of unknown function (DUF1211)
HKNFCEOD_02769 8.19e-212 - - - P - - - CorA-like Mg2+ transporter protein
HKNFCEOD_02770 3.84e-145 - - - K - - - Bacterial regulatory proteins, tetR family
HKNFCEOD_02772 2.37e-306 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HKNFCEOD_02773 1.01e-151 - - - S - - - CRISPR-associated protein (Cas_Csn2)
HKNFCEOD_02774 2.84e-62 cas2 - - L ko:K09951 - ko00000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKNFCEOD_02775 9.98e-215 cas1 - - L ko:K15342 - ko00000,ko02048,ko03400 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKNFCEOD_02776 5.56e-117 cas9 - - L ko:K09952 - ko00000,ko01000,ko02048 CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKNFCEOD_02777 1.27e-36 - - - M - - - Glycosyl transferases group 1
HKNFCEOD_02778 8.23e-54 - - - GM - - - Polysaccharide pyruvyl transferase
HKNFCEOD_02779 2.73e-33 - - - M - - - Glycosyltransferase like family 2
HKNFCEOD_02780 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HKNFCEOD_02781 0.0 bglH - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HKNFCEOD_02783 4.76e-105 - - - - - - - -
HKNFCEOD_02786 5.18e-149 - - - - - - - -
HKNFCEOD_02788 1.41e-67 - - - - - - - -
HKNFCEOD_02789 3.23e-289 - - - L - - - MULE transposase domain
HKNFCEOD_02790 1.29e-58 - - - T ko:K07172 - ko00000,ko02048 Antidote-toxin recognition MazE, bacterial antitoxin
HKNFCEOD_02791 4.49e-93 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKNFCEOD_02792 3.59e-26 - - - - - - - -
HKNFCEOD_02793 9.21e-113 repE - - K - - - Primase C terminal 1 (PriCT-1)
HKNFCEOD_02794 2.7e-127 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HKNFCEOD_02796 2.58e-228 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKNFCEOD_02797 4.17e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HKNFCEOD_02798 9.01e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKNFCEOD_02799 3.09e-122 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HKNFCEOD_02800 1.2e-87 yodB - - K - - - Transcriptional regulator, HxlR family
HKNFCEOD_02801 6.59e-90 - - - M - - - Protein of unknown function (DUF3737)
HKNFCEOD_02802 5.48e-154 - - - K ko:K12410 - ko00000,ko01000 Sir2 family
HKNFCEOD_02803 3.09e-80 pcaC 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HKNFCEOD_02804 1.02e-76 - - - K - - - helix_turn_helix, mercury resistance
HKNFCEOD_02805 2.52e-202 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKNFCEOD_02806 3.27e-256 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKNFCEOD_02807 1.55e-140 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HKNFCEOD_02808 4.9e-205 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKNFCEOD_02811 2.8e-91 - - - - - - - -
HKNFCEOD_02812 7.89e-268 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKNFCEOD_02813 0.0 mdr - - EGP - - - Major Facilitator
HKNFCEOD_02814 3.99e-106 - - - K - - - MerR HTH family regulatory protein
HKNFCEOD_02815 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HKNFCEOD_02816 7.54e-155 - - - S - - - Domain of unknown function (DUF4811)
HKNFCEOD_02817 6.08e-154 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HKNFCEOD_02818 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HKNFCEOD_02819 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HKNFCEOD_02820 9.39e-167 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HKNFCEOD_02821 1.58e-45 yhcC - - S ko:K07069 - ko00000 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
HKNFCEOD_02822 2.76e-182 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKNFCEOD_02823 2.55e-121 - - - F - - - NUDIX domain
HKNFCEOD_02825 0.0 tagE2 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKNFCEOD_02826 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HKNFCEOD_02827 9.78e-112 gpo 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HKNFCEOD_02829 9.02e-298 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HKNFCEOD_02830 0.0 cpdA - - S - - - Calcineurin-like phosphoesterase
HKNFCEOD_02831 5.05e-52 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HKNFCEOD_02832 5.58e-312 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HKNFCEOD_02833 4.22e-273 coiA - - S ko:K06198 - ko00000 Competence protein
HKNFCEOD_02834 6.41e-148 yjbH - - Q - - - Thioredoxin
HKNFCEOD_02835 7.28e-138 - - - S - - - CYTH
HKNFCEOD_02836 1.19e-158 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HKNFCEOD_02837 1.05e-193 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKNFCEOD_02838 5.81e-218 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HKNFCEOD_02839 9.8e-259 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKNFCEOD_02840 2.24e-148 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HKNFCEOD_02841 1.09e-183 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKNFCEOD_02842 9.35e-254 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HKNFCEOD_02843 1.16e-81 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HKNFCEOD_02844 4.12e-56 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKNFCEOD_02845 4.94e-245 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKNFCEOD_02846 1.94e-219 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HKNFCEOD_02847 3.44e-200 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HKNFCEOD_02848 1.86e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKNFCEOD_02849 4.04e-94 - - - S - - - Protein of unknown function (DUF1149)
HKNFCEOD_02850 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HKNFCEOD_02851 3.14e-294 ymfF - - S - - - Peptidase M16 inactive domain protein
HKNFCEOD_02852 1.13e-308 ymfH - - S - - - Peptidase M16
HKNFCEOD_02853 3.01e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HKNFCEOD_02854 1.15e-169 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HKNFCEOD_02855 9.93e-136 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKNFCEOD_02857 4.1e-291 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HKNFCEOD_02858 3.74e-243 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKNFCEOD_02859 7.95e-317 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HKNFCEOD_02860 1.14e-148 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HKNFCEOD_02861 6.41e-299 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HKNFCEOD_02862 6.13e-104 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HKNFCEOD_02863 3.24e-126 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKNFCEOD_02864 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKNFCEOD_02865 8.69e-239 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKNFCEOD_02866 1.28e-160 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 ABC transporter
HKNFCEOD_02867 1.34e-200 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKNFCEOD_02868 3.16e-258 minJ - - O - - - Domain present in PSD-95, Dlg, and ZO-1/2.
HKNFCEOD_02869 1.83e-168 phoP - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HKNFCEOD_02870 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HKNFCEOD_02871 1.76e-196 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HKNFCEOD_02872 4.48e-205 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HKNFCEOD_02873 1.51e-201 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HKNFCEOD_02874 9.06e-192 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNFCEOD_02875 3.54e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKNFCEOD_02876 3.82e-156 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HKNFCEOD_02877 0.0 yvlB - - S - - - Putative adhesin
HKNFCEOD_02878 5.23e-50 - - - - - - - -
HKNFCEOD_02879 3.07e-50 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HKNFCEOD_02880 4.78e-222 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKNFCEOD_02881 9.99e-213 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKNFCEOD_02882 1.48e-248 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HKNFCEOD_02883 1.43e-226 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKNFCEOD_02884 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKNFCEOD_02885 1.51e-148 - - - T - - - Transcriptional regulatory protein, C terminal
HKNFCEOD_02886 9.33e-222 - - - T - - - His Kinase A (phosphoacceptor) domain
HKNFCEOD_02887 1.47e-118 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HKNFCEOD_02888 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HKNFCEOD_02889 1.99e-153 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HKNFCEOD_02890 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKNFCEOD_02891 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKNFCEOD_02892 3.23e-92 - - - - - - - -
HKNFCEOD_02893 5.07e-78 - - - - - - - -
HKNFCEOD_02894 1.08e-156 azlC - - E - - - branched-chain amino acid
HKNFCEOD_02895 4.31e-65 azlD - - S - - - Branched-chain amino acid transport protein (AzlD)
HKNFCEOD_02897 1.69e-147 - - - L - - - Initiator Replication protein
HKNFCEOD_02899 4.43e-222 fruK-1 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HKNFCEOD_02900 2.36e-167 rpl - - K - - - Helix-turn-helix domain, rpiR family
HKNFCEOD_02901 8.98e-50 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKNFCEOD_02902 1.49e-97 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Transcriptional regulator
HKNFCEOD_02903 0.0 copB 3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54 - P ko:K01533,ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HKNFCEOD_02905 5.93e-12 - - - - - - - -
HKNFCEOD_02906 2.21e-74 - - - S - - - Plasmid replication protein
HKNFCEOD_02909 3.74e-57 - - - D - - - plasmid recombination enzyme
HKNFCEOD_02910 0.0 ycaM - - E - - - amino acid
HKNFCEOD_02911 1.93e-116 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HKNFCEOD_02912 8.81e-83 - - - K - - - Transcriptional regulator, LysR family
HKNFCEOD_02913 1.44e-183 - - - - - - - -
HKNFCEOD_02914 5.17e-272 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HKNFCEOD_02915 7.31e-116 - - - T - - - Nacht domain
HKNFCEOD_02916 1.69e-40 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HKNFCEOD_02917 1.47e-245 - - - E - - - Alpha/beta hydrolase family
HKNFCEOD_02918 1.86e-288 - - - C - - - Iron-containing alcohol dehydrogenase

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)