ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HCBPAAJL_00001 7.57e-211 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HCBPAAJL_00002 2.61e-19 - - - M - - - LPXTG-motif cell wall anchor domain protein
HCBPAAJL_00003 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HCBPAAJL_00004 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HCBPAAJL_00005 9.5e-39 - - - K - - - bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HCBPAAJL_00006 1.72e-208 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
HCBPAAJL_00007 5.93e-149 - - - GM - - - NAD dependent epimerase dehydratase family protein
HCBPAAJL_00008 5.96e-205 - - - K - - - Transcriptional regulator
HCBPAAJL_00009 6.27e-215 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HCBPAAJL_00010 1.08e-212 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HCBPAAJL_00011 1.31e-211 yvgN - - C - - - Aldo keto reductase
HCBPAAJL_00012 5.42e-275 - - - S - - - SLAP domain
HCBPAAJL_00013 1.7e-133 - - - K - - - Acetyltransferase (GNAT) domain
HCBPAAJL_00016 2.77e-134 - - - - - - - -
HCBPAAJL_00017 2.07e-102 - - - K - - - Transcriptional regulator
HCBPAAJL_00018 8.07e-313 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HCBPAAJL_00019 3.34e-211 - - - S - - - reductase
HCBPAAJL_00020 2.77e-220 - - - - - - - -
HCBPAAJL_00021 4.2e-42 lysR - - K - - - Transcriptional regulator
HCBPAAJL_00022 3.25e-145 glnP9 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HCBPAAJL_00023 2.48e-131 glnP7 - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter permease
HCBPAAJL_00024 6.13e-177 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00025 3.59e-205 cjaA - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HCBPAAJL_00026 2.66e-117 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCBPAAJL_00027 1.72e-142 - - - G - - - Phosphoglycerate mutase family
HCBPAAJL_00028 1.81e-223 - - - S ko:K07045 - ko00000 Amidohydrolase
HCBPAAJL_00029 5.1e-43 - - - - - - - -
HCBPAAJL_00030 1.41e-141 - - - - - - - -
HCBPAAJL_00031 3.18e-140 - - - - - - - -
HCBPAAJL_00032 3.18e-167 - - - F - - - glutamine amidotransferase
HCBPAAJL_00033 9.73e-275 - - - EGP - - - Major Facilitator Superfamily
HCBPAAJL_00034 1.7e-199 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HCBPAAJL_00035 2.53e-152 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 NUDIX domain
HCBPAAJL_00036 2.43e-100 - - - - - - - -
HCBPAAJL_00037 1.24e-113 - - - FG - - - HIT domain
HCBPAAJL_00038 5.21e-82 - - - - - - - -
HCBPAAJL_00039 4.91e-121 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HCBPAAJL_00040 1.62e-135 - - - S - - - Alpha/beta hydrolase family
HCBPAAJL_00041 6.2e-131 - - - - - - - -
HCBPAAJL_00042 1.22e-103 - - - - - - - -
HCBPAAJL_00043 2.72e-188 - - - F - - - Phosphorylase superfamily
HCBPAAJL_00044 3.34e-139 - 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Phosphoglycerate mutase family
HCBPAAJL_00045 2.07e-189 - - - F - - - Phosphorylase superfamily
HCBPAAJL_00046 1.06e-185 - - - F - - - Phosphorylase superfamily
HCBPAAJL_00047 1.79e-144 - - - S ko:K07025 - ko00000 Haloacid dehalogenase-like hydrolase
HCBPAAJL_00048 1.24e-47 - - - - - - - -
HCBPAAJL_00049 2.58e-67 mleP2 - - S ko:K07088 - ko00000 Sodium Bile acid symporter family
HCBPAAJL_00050 9.6e-137 - - - - - - - -
HCBPAAJL_00051 8.78e-52 - - - - - - - -
HCBPAAJL_00052 3.77e-216 mleR - - K - - - LysR family
HCBPAAJL_00053 0.0 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HCBPAAJL_00054 3.74e-130 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HCBPAAJL_00055 2.2e-310 - - - L ko:K07478 - ko00000 AAA C-terminal domain
HCBPAAJL_00056 2.27e-248 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCBPAAJL_00057 5.33e-147 - - - S - - - L,D-transpeptidase catalytic domain
HCBPAAJL_00058 1.23e-278 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HCBPAAJL_00059 3.03e-115 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCBPAAJL_00060 2.55e-118 - - - L - - - nuclease
HCBPAAJL_00061 2.51e-198 - - - F ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HCBPAAJL_00062 2.81e-148 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HCBPAAJL_00063 5.39e-308 steT - - E ko:K03294 - ko00000 amino acid
HCBPAAJL_00064 4.4e-138 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HCBPAAJL_00065 6.01e-54 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HCBPAAJL_00066 3.16e-190 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HCBPAAJL_00067 0.0 ppc 4.1.1.31 - C ko:K01595 ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate carboxylase activity
HCBPAAJL_00068 0.0 - - - - - - - -
HCBPAAJL_00069 0.0 - - - - - - - -
HCBPAAJL_00070 2.29e-224 yobV3 - - K - - - WYL domain
HCBPAAJL_00071 4.35e-108 - - - S - - - Pyridoxamine 5'-phosphate oxidase
HCBPAAJL_00072 1.57e-187 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 reductase
HCBPAAJL_00073 3.78e-72 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HCBPAAJL_00074 1.16e-148 - - - C - - - Aldo/keto reductase family
HCBPAAJL_00075 7.12e-80 - - - C - - - aldo keto reductase
HCBPAAJL_00076 1.54e-187 - - - U ko:K05340 - ko00000,ko02000 ribose uptake protein RbsU
HCBPAAJL_00077 1.51e-24 - - - C - - - Flavodoxin
HCBPAAJL_00079 9.87e-139 - - - C - - - Flavodoxin
HCBPAAJL_00080 2.88e-130 - - - P - - - esterase
HCBPAAJL_00081 0.0 gshR3 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Glutathione reductase
HCBPAAJL_00082 3.77e-32 - - - - - - - -
HCBPAAJL_00083 1.29e-182 - - - C - - - Flavodoxin
HCBPAAJL_00084 7.38e-127 - - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HCBPAAJL_00085 3.1e-30 - - - C - - - Flavodoxin
HCBPAAJL_00086 1.39e-190 - - - P - - - FAD-binding domain
HCBPAAJL_00087 2.54e-101 adh2 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HCBPAAJL_00089 0.0 yagE - - E - - - amino acid
HCBPAAJL_00090 1.37e-15 - - - S - - - Alpha beta hydrolase
HCBPAAJL_00091 6e-59 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBPAAJL_00092 4.13e-18 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCBPAAJL_00093 1.43e-24 nth2 - - L ko:K07457 - ko00000 Base excision DNA repair protein, HhH-GPD family
HCBPAAJL_00094 8.53e-215 - - - S - - - Conserved hypothetical protein 698
HCBPAAJL_00095 1.17e-130 - - - - - - - -
HCBPAAJL_00096 1.9e-140 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCBPAAJL_00097 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBPAAJL_00098 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCBPAAJL_00099 3.72e-237 - - - K - - - Transcriptional regulator
HCBPAAJL_00100 3.65e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HCBPAAJL_00101 7.02e-146 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCBPAAJL_00102 9.73e-55 - - - K - - - Helix-turn-helix domain
HCBPAAJL_00103 4.78e-165 - - - S - - - Protein of unknown function (DUF1275)
HCBPAAJL_00104 3.46e-87 fic - - D ko:K04095 - ko00000,ko03036 Fic/DOC family
HCBPAAJL_00106 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HCBPAAJL_00107 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HCBPAAJL_00108 1.74e-272 - - - EGP - - - Transmembrane secretion effector
HCBPAAJL_00109 1.06e-110 rmaD - - K - - - transcriptional
HCBPAAJL_00110 3.92e-76 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCBPAAJL_00111 3.43e-07 azoR - - C ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCBPAAJL_00112 2.71e-256 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HCBPAAJL_00113 2.62e-138 XK27_00160 - - S - - - Domain of unknown function (DUF5052)
HCBPAAJL_00114 1.27e-119 flaR - - F - - - topology modulation protein
HCBPAAJL_00115 1.03e-100 - - - - - - - -
HCBPAAJL_00116 5.95e-250 xerS - - L ko:K03733 - ko00000,ko03036 Belongs to the 'phage' integrase family
HCBPAAJL_00117 6.18e-205 - - - S - - - EDD domain protein, DegV family
HCBPAAJL_00118 2.95e-87 - - - - - - - -
HCBPAAJL_00119 0.0 FbpA - - K - - - Fibronectin-binding protein
HCBPAAJL_00120 0.0 carB1 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HCBPAAJL_00121 2.05e-255 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HCBPAAJL_00122 2.88e-219 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HCBPAAJL_00123 6.03e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCBPAAJL_00124 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HCBPAAJL_00125 2.01e-310 cpdA - - S - - - Calcineurin-like phosphoesterase
HCBPAAJL_00126 2.39e-277 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HCBPAAJL_00127 2.83e-90 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCBPAAJL_00128 1.61e-136 ypsA - - S - - - Belongs to the UPF0398 family
HCBPAAJL_00129 1.99e-151 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCBPAAJL_00130 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HCBPAAJL_00131 4.71e-149 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCBPAAJL_00132 1.39e-148 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HCBPAAJL_00133 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HCBPAAJL_00134 8.23e-117 ypmB - - S - - - Protein conserved in bacteria
HCBPAAJL_00135 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HCBPAAJL_00136 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HCBPAAJL_00137 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCBPAAJL_00138 6.78e-218 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 GHMP kinases N terminal domain
HCBPAAJL_00139 3.39e-227 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HCBPAAJL_00140 1.64e-261 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HCBPAAJL_00141 2.09e-242 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCBPAAJL_00142 1.01e-187 - - - K - - - SIS domain
HCBPAAJL_00143 1.18e-140 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HCBPAAJL_00144 2.04e-73 XK27_10475 - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HCBPAAJL_00145 1.14e-275 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HCBPAAJL_00146 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HCBPAAJL_00147 1.05e-228 - - - - - - - -
HCBPAAJL_00148 1.57e-181 - - - - - - - -
HCBPAAJL_00149 1.72e-123 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HCBPAAJL_00150 1.04e-37 - - - - - - - -
HCBPAAJL_00151 3.64e-175 - - - - - - - -
HCBPAAJL_00152 2.03e-186 - - - - - - - -
HCBPAAJL_00153 1.51e-174 - - - - - - - -
HCBPAAJL_00154 1.09e-160 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HCBPAAJL_00155 1.25e-80 lexA - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator, GntR family
HCBPAAJL_00156 7.64e-313 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HCBPAAJL_00157 3.45e-197 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCBPAAJL_00158 4.48e-161 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HCBPAAJL_00159 1.87e-106 - 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HCBPAAJL_00160 2.24e-162 - - - S - - - Peptidase family M23
HCBPAAJL_00161 3.01e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCBPAAJL_00162 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCBPAAJL_00163 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HCBPAAJL_00164 1.05e-227 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HCBPAAJL_00165 5.41e-173 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HCBPAAJL_00166 6.28e-218 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCBPAAJL_00167 3.58e-129 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCBPAAJL_00168 1.82e-226 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HCBPAAJL_00169 4.38e-92 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HCBPAAJL_00170 4.83e-30 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HCBPAAJL_00171 4.68e-197 yqfL 2.7.11.33, 2.7.4.28 - F ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCBPAAJL_00172 3.22e-133 - - - S - - - Peptidase family M23
HCBPAAJL_00173 6.31e-144 msrA 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCBPAAJL_00174 2.17e-209 yitT - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBPAAJL_00175 1.4e-157 - - - - - - - -
HCBPAAJL_00176 4.04e-207 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCBPAAJL_00177 1.58e-282 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HCBPAAJL_00178 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HCBPAAJL_00179 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HCBPAAJL_00180 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HCBPAAJL_00181 3.65e-28 - - - S - - - Bacterial protein of unknown function (DUF898)
HCBPAAJL_00182 1.92e-141 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HCBPAAJL_00183 0.0 - - - - ko:K14201 ko05150,map05150 ko00000,ko00001 -
HCBPAAJL_00184 2.86e-05 - - - M - - - Leucine-rich repeat (LRR) protein
HCBPAAJL_00185 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HCBPAAJL_00186 5.4e-282 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HCBPAAJL_00187 0.0 - - - - - - - -
HCBPAAJL_00188 3.69e-157 - - - G - - - Antibiotic biosynthesis monooxygenase
HCBPAAJL_00189 8.29e-129 - - - - - - - -
HCBPAAJL_00190 1.82e-139 - - - K - - - LysR substrate binding domain
HCBPAAJL_00191 8.62e-22 - - - - - - - -
HCBPAAJL_00192 3.35e-291 - - - S - - - Sterol carrier protein domain
HCBPAAJL_00193 3.83e-127 citX 2.7.7.61 - HI ko:K05964 ko02020,map02020 ko00000,ko00001,ko01000 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HCBPAAJL_00194 3.72e-201 lysR5 - - K - - - LysR substrate binding domain
HCBPAAJL_00195 0.0 - - - P - - - Cation transporter/ATPase, N-terminus
HCBPAAJL_00196 1.19e-113 - 3.4.21.96 - S ko:K01361 - ko00000,ko01000,ko01002,ko03110 SLAP domain
HCBPAAJL_00197 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBPAAJL_00198 4.53e-196 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HCBPAAJL_00199 1.73e-219 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HCBPAAJL_00200 1.72e-269 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HCBPAAJL_00201 6.15e-194 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCBPAAJL_00203 7.02e-103 - - - K - - - Acetyltransferase (GNAT) domain
HCBPAAJL_00204 2.41e-123 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCBPAAJL_00205 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HCBPAAJL_00206 6.07e-155 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HCBPAAJL_00207 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCBPAAJL_00208 5.85e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCBPAAJL_00209 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HCBPAAJL_00210 7.55e-109 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCBPAAJL_00211 2.1e-247 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCBPAAJL_00212 0.0 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HCBPAAJL_00213 2.49e-228 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HCBPAAJL_00214 8.54e-214 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCBPAAJL_00215 9.65e-79 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCBPAAJL_00216 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCBPAAJL_00217 3.95e-65 ylxQ - - J - - - ribosomal protein
HCBPAAJL_00218 6.47e-64 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HCBPAAJL_00219 3.76e-268 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HCBPAAJL_00220 2.39e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HCBPAAJL_00221 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBPAAJL_00222 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCBPAAJL_00223 1.35e-255 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HCBPAAJL_00224 1.89e-188 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HCBPAAJL_00225 2.23e-178 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCBPAAJL_00226 2.53e-114 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCBPAAJL_00227 7.13e-169 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HCBPAAJL_00228 1.45e-234 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCBPAAJL_00229 2.05e-181 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HCBPAAJL_00230 6.34e-255 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HCBPAAJL_00231 1.59e-149 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HCBPAAJL_00232 9.32e-296 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HCBPAAJL_00233 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HCBPAAJL_00234 0.0 mdlB - - V ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_00235 0.0 mdlA - - V ko:K06148,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_00236 3.18e-41 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HCBPAAJL_00237 2.97e-50 ynzC - - S - - - UPF0291 protein
HCBPAAJL_00238 2.83e-145 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCBPAAJL_00239 1.4e-185 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HCBPAAJL_00240 1.19e-156 ung2 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HCBPAAJL_00241 2.58e-226 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HCBPAAJL_00242 0.0 - - - S - - - Bacterial membrane protein, YfhO
HCBPAAJL_00243 3.52e-91 - - - S - - - GtrA-like protein
HCBPAAJL_00244 2.28e-74 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCBPAAJL_00245 5.01e-164 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HCBPAAJL_00246 1.07e-124 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCBPAAJL_00247 6.78e-60 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HCBPAAJL_00248 1.9e-289 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCBPAAJL_00249 3.35e-73 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCBPAAJL_00250 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HCBPAAJL_00251 1.16e-88 - - - - - - - -
HCBPAAJL_00252 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBPAAJL_00253 1.12e-228 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCBPAAJL_00254 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HCBPAAJL_00255 4.48e-161 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCBPAAJL_00256 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HCBPAAJL_00257 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HCBPAAJL_00258 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HCBPAAJL_00259 5.84e-202 oppC5 - - P ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_00260 1.28e-226 oppB - - P ko:K02033,ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_00261 8.73e-234 oppF - - P ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_00262 1.43e-251 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_00263 1.53e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCBPAAJL_00264 3.16e-234 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCBPAAJL_00265 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCBPAAJL_00266 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HCBPAAJL_00267 1.67e-74 yloU - - S - - - Asp23 family, cell envelope-related function
HCBPAAJL_00268 2.29e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HCBPAAJL_00269 1.5e-68 - - - - - - - -
HCBPAAJL_00270 3.29e-163 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HCBPAAJL_00271 5.27e-154 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HCBPAAJL_00272 1.37e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCBPAAJL_00273 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HCBPAAJL_00274 9.79e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HCBPAAJL_00275 4.61e-313 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCBPAAJL_00276 1.08e-220 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCBPAAJL_00277 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCBPAAJL_00278 2.37e-46 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCBPAAJL_00279 2.53e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HCBPAAJL_00280 2.88e-105 - - - S - - - ASCH
HCBPAAJL_00281 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HCBPAAJL_00282 1.52e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HCBPAAJL_00283 1.84e-204 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HCBPAAJL_00284 3.76e-48 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBPAAJL_00285 5.86e-310 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCBPAAJL_00286 5.91e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCBPAAJL_00287 1.28e-85 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCBPAAJL_00288 2.57e-94 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HCBPAAJL_00289 6.05e-133 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCBPAAJL_00290 3.69e-258 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HCBPAAJL_00291 7.95e-64 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HCBPAAJL_00292 4.8e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HCBPAAJL_00293 3.54e-192 - - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBPAAJL_00294 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HCBPAAJL_00295 3.98e-257 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HCBPAAJL_00296 4.18e-38 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HCBPAAJL_00297 4.41e-137 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HCBPAAJL_00298 9.64e-141 - - - Q - - - Imidazolonepropionase and related amidohydrolases
HCBPAAJL_00299 7.45e-09 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_00300 9.58e-80 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_00301 7.38e-127 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_00302 3.88e-196 - 2.7.1.95 - F ko:K00897 - ko00000,ko01000,ko01504 Belongs to the aminoglycoside phosphotransferase family
HCBPAAJL_00303 0.0 - - - S - - - Predicted membrane protein (DUF2207)
HCBPAAJL_00304 3.04e-198 cinI - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HCBPAAJL_00305 1.16e-162 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HCBPAAJL_00306 1.75e-95 - - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HCBPAAJL_00308 4.22e-211 - - - S - - - Membrane
HCBPAAJL_00309 1.75e-227 lipA - - I - - - Carboxylesterase family
HCBPAAJL_00310 4.8e-87 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HCBPAAJL_00311 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HCBPAAJL_00312 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HCBPAAJL_00313 1.84e-195 supH - - S - - - haloacid dehalogenase-like hydrolase
HCBPAAJL_00314 1.64e-262 - - - - - - - -
HCBPAAJL_00315 1.71e-211 - - - - - - - -
HCBPAAJL_00316 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HCBPAAJL_00317 0.0 - 3.2.1.177 GH31 G ko:K01811 - ko00000,ko01000 Belongs to the glycosyl hydrolase 31 family
HCBPAAJL_00318 0.0 - 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_00319 7.89e-213 - 2.7.1.85 - GK ko:K18673 - ko00000,ko01000 ROK family
HCBPAAJL_00320 3.58e-262 xylR - - GK - - - ROK family
HCBPAAJL_00321 4.19e-302 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_00322 9.35e-128 - - - S - - - Bacterial PH domain
HCBPAAJL_00323 3.5e-22 - - - - - - - -
HCBPAAJL_00324 1.02e-85 - - - K - - - sequence-specific DNA binding
HCBPAAJL_00325 2.45e-63 - - - S - - - Motility quorum-sensing regulator, toxin of MqsA
HCBPAAJL_00326 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCBPAAJL_00327 1.67e-104 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HCBPAAJL_00328 2.43e-62 - - - - - - - -
HCBPAAJL_00329 1.74e-192 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HCBPAAJL_00330 0.0 - - - - - - - -
HCBPAAJL_00331 2.73e-07 - - - D - - - Domain of Unknown Function (DUF1542)
HCBPAAJL_00332 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HCBPAAJL_00333 2.85e-267 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HCBPAAJL_00334 5.02e-314 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCBPAAJL_00335 3.43e-235 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HCBPAAJL_00336 1.75e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCBPAAJL_00337 1.94e-215 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCBPAAJL_00338 7.44e-168 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCBPAAJL_00339 2.73e-154 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCBPAAJL_00340 3.3e-152 - - - GM - - - NmrA-like family
HCBPAAJL_00341 0.0 yoaB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HCBPAAJL_00342 9.28e-317 eriC - - P ko:K03281 - ko00000 chloride
HCBPAAJL_00343 1.86e-141 - - - O - - - Matrixin
HCBPAAJL_00344 0.0 - - - M - - - LPXTG-motif cell wall anchor domain protein
HCBPAAJL_00345 3.89e-122 - - - K - - - acetyltransferase
HCBPAAJL_00346 1.65e-66 - - - - - - - -
HCBPAAJL_00347 2.34e-204 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HCBPAAJL_00348 2.87e-62 - - - - - - - -
HCBPAAJL_00349 7.22e-161 - 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HCBPAAJL_00350 1.15e-200 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCBPAAJL_00351 2.66e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
HCBPAAJL_00352 0.0 oppA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HCBPAAJL_00354 0.0 npr 1.11.1.1 - C ko:K05910 - ko00000,ko01000 NADH oxidase
HCBPAAJL_00355 7.81e-82 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HCBPAAJL_00356 3.88e-60 - - - D ko:K19159 - ko00000,ko02048 Antitoxin component of a toxin-antitoxin (TA) module
HCBPAAJL_00357 1.77e-150 ylbE - - GM - - - NAD(P)H-binding
HCBPAAJL_00358 2.97e-76 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCBPAAJL_00359 1.08e-85 - - - S - - - ASCH domain
HCBPAAJL_00360 6.71e-153 - - - S - - - GyrI-like small molecule binding domain
HCBPAAJL_00362 1.3e-206 - - - K - - - Bacterial regulatory helix-turn-helix protein, lysR family
HCBPAAJL_00363 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
HCBPAAJL_00366 2.26e-267 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
HCBPAAJL_00367 1.63e-169 - - - T - - - Putative diguanylate phosphodiesterase
HCBPAAJL_00368 8.74e-192 - - - T - - - EAL domain
HCBPAAJL_00369 8.31e-313 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HCBPAAJL_00370 3.07e-119 - - - - - - - -
HCBPAAJL_00371 9.37e-227 - - - C - - - Oxidoreductase
HCBPAAJL_00373 4.69e-271 - - - L ko:K07496 - ko00000 TIGRFAM transposase, IS605 OrfB family
HCBPAAJL_00374 4.27e-37 - - - C - - - pentaerythritol trinitrate reductase activity
HCBPAAJL_00375 4.83e-141 pncA - - Q - - - Isochorismatase family
HCBPAAJL_00376 2.86e-19 - - - - - - - -
HCBPAAJL_00377 0.0 potE - - E - - - Amino Acid
HCBPAAJL_00378 2.05e-163 - - - S - - - Alpha beta hydrolase
HCBPAAJL_00380 1.31e-165 - - - - - - - -
HCBPAAJL_00381 5.44e-163 - - - S - - - L-ascorbic acid biosynthetic process
HCBPAAJL_00382 8.84e-93 - - - O - - - OsmC-like protein
HCBPAAJL_00383 3.65e-272 - - - EGP - - - Major Facilitator Superfamily
HCBPAAJL_00384 9.45e-298 sptS - - T - - - Histidine kinase
HCBPAAJL_00385 1.28e-152 dltr - - K - - - response regulator
HCBPAAJL_00386 4.2e-147 - - - T - - - Region found in RelA / SpoT proteins
HCBPAAJL_00387 7.55e-241 dhaK 2.7.1.121 - G ko:K05878 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak1 domain
HCBPAAJL_00388 1.31e-134 dhaL 2.7.1.121 - S ko:K05879 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Dak2
HCBPAAJL_00389 8.2e-81 dhaM 2.7.1.121 - S ko:K05881 ko00561,map00561 ko00000,ko00001,ko01000,ko02000 PTS system fructose IIA component
HCBPAAJL_00390 1.63e-171 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HCBPAAJL_00391 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HCBPAAJL_00392 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HCBPAAJL_00393 3.33e-266 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_00394 3.56e-196 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_00395 1.98e-200 msmF - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_00396 6.26e-309 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HCBPAAJL_00397 7.27e-206 lacR - - K - - - helix_turn_helix, arabinose operon control protein
HCBPAAJL_00398 2.78e-98 - - - K - - - MerR HTH family regulatory protein
HCBPAAJL_00399 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HCBPAAJL_00400 4.02e-124 - - - S - - - Domain of unknown function (DUF4811)
HCBPAAJL_00401 9.46e-67 - - - S - - - Domain of unknown function (DUF4160)
HCBPAAJL_00402 1.53e-61 - - - - - - - -
HCBPAAJL_00404 3.46e-53 - - - C - - - FMN binding
HCBPAAJL_00405 1.42e-215 - - - S - - - SLAP domain
HCBPAAJL_00406 6.76e-247 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HCBPAAJL_00407 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HCBPAAJL_00408 7.5e-283 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCBPAAJL_00409 9.91e-241 - - - M - - - domain protein
HCBPAAJL_00410 1.51e-145 - - - - - - - -
HCBPAAJL_00411 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HCBPAAJL_00412 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HCBPAAJL_00413 8.14e-286 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HCBPAAJL_00414 1.46e-240 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HCBPAAJL_00415 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HCBPAAJL_00416 8.15e-242 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HCBPAAJL_00417 1.79e-243 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HCBPAAJL_00418 0.0 - - - S - - - Domain of unknown function (DUF5060)
HCBPAAJL_00419 1.05e-274 - - - EGP - - - Transporter, major facilitator family protein
HCBPAAJL_00420 2.88e-223 rbsR - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HCBPAAJL_00421 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain
HCBPAAJL_00422 2e-79 - - - G - - - polysaccharide catabolic process
HCBPAAJL_00423 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HCBPAAJL_00424 9.97e-103 - 3.5.1.105 - G ko:K03478 - ko00000,ko01000 YdjC-like protein
HCBPAAJL_00425 4.63e-225 - - - I - - - alpha/beta hydrolase fold
HCBPAAJL_00426 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_00427 5.47e-199 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HCBPAAJL_00428 0.0 - - - G - - - Protein of unknown function (DUF4038)
HCBPAAJL_00429 1.05e-225 - - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein domain
HCBPAAJL_00430 8.27e-190 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HCBPAAJL_00431 2.7e-10 rbsC - - U ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HCBPAAJL_00432 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HCBPAAJL_00433 1.43e-87 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCBPAAJL_00434 1.11e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCBPAAJL_00435 0.0 - - - G - - - isomerase
HCBPAAJL_00436 1.41e-286 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HCBPAAJL_00437 9.9e-240 purR13 - - K ko:K02529 - ko00000,ko03000 Bacterial regulatory proteins, lacI family
HCBPAAJL_00438 5.73e-202 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
HCBPAAJL_00439 2.68e-225 - 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyrimidine binding domain
HCBPAAJL_00440 0.0 glpK3 2.7.1.30 - G ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 FGGY family of carbohydrate kinases, C-terminal domain
HCBPAAJL_00441 1.12e-287 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBPAAJL_00442 8.07e-315 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HCBPAAJL_00445 2.37e-210 - - - - - - - -
HCBPAAJL_00446 5.77e-214 - - - - - - - -
HCBPAAJL_00447 7.72e-152 ybbL - - S ko:K02068 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00448 7.05e-171 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 Uncharacterised protein family (UPF0014)
HCBPAAJL_00449 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HCBPAAJL_00450 4.04e-304 ynbB - - P - - - aluminum resistance
HCBPAAJL_00451 8.27e-221 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCBPAAJL_00452 1.48e-90 yqhL - - P - - - Rhodanese-like protein
HCBPAAJL_00453 4.01e-44 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HCBPAAJL_00454 4.62e-153 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Rhomboid family
HCBPAAJL_00455 3.23e-127 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCBPAAJL_00456 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HCBPAAJL_00457 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HCBPAAJL_00458 0.0 - - - S - - - membrane
HCBPAAJL_00459 2.46e-218 - - - G - - - BadF/BadG/BcrA/BcrD ATPase family
HCBPAAJL_00460 0.0 prtB 3.4.21.96 - O ko:K01361 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HCBPAAJL_00461 1.06e-69 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HCBPAAJL_00462 3.51e-17 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HCBPAAJL_00463 0.0 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HCBPAAJL_00464 1.6e-217 ldh3 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 lactate/malate dehydrogenase, alpha/beta C-terminal domain
HCBPAAJL_00465 3.63e-94 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBPAAJL_00466 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBPAAJL_00467 2.59e-257 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCBPAAJL_00468 1.24e-83 yodB - - K - - - Transcriptional regulator, HxlR family
HCBPAAJL_00469 3.67e-178 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBPAAJL_00470 1.37e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HCBPAAJL_00471 1.89e-209 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBPAAJL_00472 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HCBPAAJL_00473 6.08e-164 csrR - - K - - - response regulator
HCBPAAJL_00474 3.14e-127 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HCBPAAJL_00475 9.35e-275 ylbM - - S - - - Belongs to the UPF0348 family
HCBPAAJL_00476 3.58e-78 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCBPAAJL_00477 4.06e-145 yqeK - - H - - - Hydrolase, HD family
HCBPAAJL_00478 8.11e-159 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCBPAAJL_00479 4.26e-273 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HCBPAAJL_00480 1.66e-120 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HCBPAAJL_00481 4.78e-253 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HCBPAAJL_00482 8.82e-241 add 3.5.4.2, 3.5.4.4 - F ko:K01488,ko:K02029,ko:K21053 ko00230,ko01100,ko05340,map00230,map01100,map05340 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HCBPAAJL_00483 4.31e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCBPAAJL_00484 2.36e-38 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HCBPAAJL_00485 1.71e-95 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCBPAAJL_00486 1.92e-118 - - - - - - - -
HCBPAAJL_00487 1.39e-92 - - - S - - - Protein of unknown function (DUF3021)
HCBPAAJL_00488 2.67e-96 - - - K - - - LytTr DNA-binding domain
HCBPAAJL_00489 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCBPAAJL_00490 5.35e-215 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HCBPAAJL_00491 0.0 dnaB2 - - L ko:K03346 - ko00000,ko03032 Replication initiation and membrane attachment
HCBPAAJL_00492 1.29e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCBPAAJL_00493 5.52e-139 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCBPAAJL_00494 6.72e-205 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCBPAAJL_00495 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCBPAAJL_00496 0.0 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HCBPAAJL_00497 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HCBPAAJL_00498 3.61e-144 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCBPAAJL_00499 3.52e-253 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HCBPAAJL_00500 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCBPAAJL_00501 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBPAAJL_00502 1.15e-165 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBPAAJL_00503 1.88e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCBPAAJL_00504 1.24e-172 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HCBPAAJL_00505 1.85e-269 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCBPAAJL_00506 7.36e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCBPAAJL_00507 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HCBPAAJL_00508 1.9e-160 - - - C - - - Flavodoxin
HCBPAAJL_00509 5.58e-192 hflC - - O ko:K04087 - ko00000,ko00002,ko01000 prohibitin homologues
HCBPAAJL_00510 2.68e-67 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HCBPAAJL_00511 2.76e-249 - - - S - - - Bacteriocin helveticin-J
HCBPAAJL_00512 0.0 - - - M - - - Peptidase family M1 domain
HCBPAAJL_00513 2.45e-227 - - - S - - - SLAP domain
HCBPAAJL_00514 2.86e-146 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HCBPAAJL_00515 5.44e-127 tnpB - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HCBPAAJL_00516 6.25e-304 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HCBPAAJL_00517 2.45e-214 - 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Arginase family
HCBPAAJL_00518 1.09e-135 - - - S - - - Membrane
HCBPAAJL_00519 0.0 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_00520 0.0 - - - G ko:K02755,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_00521 2.24e-41 - 2.7.1.208, 2.7.1.211 - G ko:K02749,ko:K02750,ko:K02755,ko:K02756,ko:K02757,ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HCBPAAJL_00522 2.69e-191 - - - K - - - Helix-turn-helix domain, rpiR family
HCBPAAJL_00523 0.0 - - - - - - - -
HCBPAAJL_00524 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HCBPAAJL_00525 3.06e-157 XK27_10290 - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCBPAAJL_00526 5.52e-71 ytpP - - CO - - - Thioredoxin
HCBPAAJL_00527 9.15e-165 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCBPAAJL_00528 3.37e-273 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HCBPAAJL_00529 3.15e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00530 1.38e-102 hit - - FG ko:K02503 - ko00000,ko04147 Scavenger mRNA decapping enzyme C-term binding
HCBPAAJL_00531 3.51e-74 - - - - - - - -
HCBPAAJL_00532 3.26e-199 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCBPAAJL_00533 3.19e-239 yhaM - - S ko:K03698 - ko00000,ko01000,ko03019 Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBPAAJL_00534 0.0 yhaN - - L - - - AAA domain
HCBPAAJL_00535 8.31e-295 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HCBPAAJL_00536 6.93e-72 yheA - - S - - - Belongs to the UPF0342 family
HCBPAAJL_00537 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HCBPAAJL_00538 3.09e-208 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HCBPAAJL_00539 1.34e-182 glpF - - U ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HCBPAAJL_00540 2.79e-154 - - - - - - - -
HCBPAAJL_00541 2.45e-246 - - - C - - - FMN-dependent dehydrogenase
HCBPAAJL_00542 1.48e-217 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HCBPAAJL_00543 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HCBPAAJL_00544 1.06e-164 - - - M - - - ErfK YbiS YcfS YnhG
HCBPAAJL_00545 3.16e-197 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCBPAAJL_00546 3.95e-310 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HCBPAAJL_00548 1.19e-71 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HCBPAAJL_00549 4.1e-251 flp - - V - - - Beta-lactamase
HCBPAAJL_00550 3.16e-72 - - - - - - - -
HCBPAAJL_00551 0.0 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphatidylserine decarboxylase family
HCBPAAJL_00552 4.95e-53 - - - S - - - Enterocin A Immunity
HCBPAAJL_00553 0.0 - - - S - - - domain, Protein
HCBPAAJL_00554 6.41e-105 - - - S - - - Cupin domain
HCBPAAJL_00555 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
HCBPAAJL_00556 1.39e-22 - - - K - - - transcriptional regulator
HCBPAAJL_00557 3.3e-94 - - - K - - - transcriptional regulator
HCBPAAJL_00559 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HCBPAAJL_00560 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HCBPAAJL_00561 7.75e-153 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HCBPAAJL_00562 7.6e-118 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HCBPAAJL_00563 1.74e-145 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HCBPAAJL_00564 1.37e-36 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HCBPAAJL_00565 0.0 mdr - - EGP - - - Major Facilitator
HCBPAAJL_00566 5.35e-289 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCBPAAJL_00571 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCBPAAJL_00572 1.28e-131 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HCBPAAJL_00573 1.47e-144 - - - S - - - SNARE associated Golgi protein
HCBPAAJL_00574 1.84e-196 - - - I - - - alpha/beta hydrolase fold
HCBPAAJL_00575 4.92e-207 plcR - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HCBPAAJL_00576 3.62e-121 - - - F - - - Nucleoside 2-deoxyribosyltransferase
HCBPAAJL_00577 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HCBPAAJL_00578 0.0 - - - M - - - Rib/alpha-like repeat
HCBPAAJL_00579 0.0 - - - M - - - Rib/alpha-like repeat
HCBPAAJL_00580 6.9e-220 - - - - - - - -
HCBPAAJL_00581 0.0 ydgH - - S ko:K06994 - ko00000 MMPL family
HCBPAAJL_00582 1.8e-124 yobS - - K - - - Bacterial regulatory proteins, tetR family
HCBPAAJL_00583 2.62e-198 - 3.5.2.6 - V ko:K17836 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 Beta-lactamase enzyme family
HCBPAAJL_00584 7.19e-202 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HCBPAAJL_00585 2.47e-309 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HCBPAAJL_00586 0.0 - - - S - - - Zn-dependent metallo-hydrolase RNA specificity domain
HCBPAAJL_00587 1.68e-188 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_00588 1.24e-197 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
HCBPAAJL_00589 3.18e-258 malK - - P ko:K10112,ko:K17240 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HCBPAAJL_00590 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBPAAJL_00591 4.53e-203 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HCBPAAJL_00592 4e-234 - 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 EXOIII
HCBPAAJL_00593 4.72e-200 - - - K - - - NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HCBPAAJL_00594 7.21e-150 yviA - - S - - - Protein of unknown function (DUF421)
HCBPAAJL_00595 9.54e-97 - - - S - - - Protein of unknown function (DUF3290)
HCBPAAJL_00596 0.0 - - - M - - - domain protein
HCBPAAJL_00597 3.05e-181 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HCBPAAJL_00598 0.0 - - - - - - - -
HCBPAAJL_00599 7.95e-64 - - - - - - - -
HCBPAAJL_00600 9.1e-184 - - - S - - - PAS domain
HCBPAAJL_00601 0.0 - - - V - - - ABC transporter transmembrane region
HCBPAAJL_00602 5.44e-230 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HCBPAAJL_00603 2.91e-164 - - - T - - - Transcriptional regulatory protein, C terminal
HCBPAAJL_00604 4.14e-312 - - - T - - - GHKL domain
HCBPAAJL_00605 2.36e-112 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HCBPAAJL_00606 1.34e-131 - - - S - - - Peptidase propeptide and YPEB domain
HCBPAAJL_00607 4.9e-100 yybA - - K - - - Transcriptional regulator
HCBPAAJL_00608 3.59e-123 XK27_03150 2.3.1.57 - K ko:K22441 - ko00000,ko01000 Acetyltransferase (GNAT) domain
HCBPAAJL_00609 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HCBPAAJL_00610 2.28e-72 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HCBPAAJL_00611 9.2e-130 - - - S - - - Peptidase propeptide and YPEB domain
HCBPAAJL_00612 8.57e-134 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCBPAAJL_00613 3.51e-221 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HCBPAAJL_00614 1.68e-133 - - - E - - - GDSL-like Lipase/Acylhydrolase
HCBPAAJL_00615 1.25e-106 yjcF - - S - - - Acetyltransferase (GNAT) domain
HCBPAAJL_00616 2.71e-193 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HCBPAAJL_00617 1.29e-140 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter
HCBPAAJL_00618 3e-139 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HCBPAAJL_00619 2.14e-31 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HCBPAAJL_00620 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HCBPAAJL_00621 1.69e-160 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HCBPAAJL_00622 7.53e-163 gpm2 - - G - - - Phosphoglycerate mutase family
HCBPAAJL_00623 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HCBPAAJL_00624 3.02e-174 cysA - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00625 7.62e-308 - - - S - - - response to antibiotic
HCBPAAJL_00626 1.39e-164 - - - - - - - -
HCBPAAJL_00627 0.0 pacL3 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HCBPAAJL_00628 3.66e-85 - 2.7.1.191 - G ko:K02793 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HCBPAAJL_00629 3.45e-64 - - - - - - - -
HCBPAAJL_00630 1.25e-22 - - - - - - - -
HCBPAAJL_00631 1.35e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HCBPAAJL_00632 7.07e-178 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HCBPAAJL_00633 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase C-terminal domain
HCBPAAJL_00634 8.44e-201 - - - - - - - -
HCBPAAJL_00635 1.6e-119 - - - - - - - -
HCBPAAJL_00636 3.39e-138 - - - K ko:K06977 - ko00000 acetyltransferase
HCBPAAJL_00639 0.0 aspD 4.1.1.12 - E ko:K09758 ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230 ko00000,ko00001,ko01000 Aminotransferase
HCBPAAJL_00640 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HCBPAAJL_00641 5.59e-250 - - - S - - - Domain of unknown function (DUF4767)
HCBPAAJL_00642 1.56e-256 - - - S - - - Membrane
HCBPAAJL_00643 1.71e-191 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HCBPAAJL_00644 7.86e-240 - - - K - - - helix_turn_helix, arabinose operon control protein
HCBPAAJL_00645 3.86e-239 - - - K - - - helix_turn_helix, arabinose operon control protein
HCBPAAJL_00646 1.96e-192 yleF - - K - - - Helix-turn-helix domain, rpiR family
HCBPAAJL_00647 1.06e-258 yleB 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HCBPAAJL_00648 1.24e-202 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCBPAAJL_00649 0.0 pts32BC 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_00650 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_00651 0.0 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_00652 4.37e-205 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HCBPAAJL_00653 0.0 - - - M - - - Leucine-rich repeat (LRR) protein
HCBPAAJL_00655 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 belongs to the glycosyl hydrolase 13 family
HCBPAAJL_00656 4.05e-119 - - - - - - - -
HCBPAAJL_00657 6.91e-235 - - - - - - - -
HCBPAAJL_00658 0.0 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2326)
HCBPAAJL_00665 1.31e-211 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HCBPAAJL_00666 6.89e-280 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCBPAAJL_00667 2.52e-84 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HCBPAAJL_00668 1.63e-175 - - - L ko:K07483 - ko00000 transposase activity
HCBPAAJL_00669 1.34e-298 - - - L - - - COG3547 Transposase and inactivated derivatives
HCBPAAJL_00670 0.0 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HCBPAAJL_00671 7.05e-126 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HCBPAAJL_00672 1.31e-93 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 Flavin containing amine oxidoreductase
HCBPAAJL_00673 1.86e-287 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HCBPAAJL_00674 7.58e-244 XK27_01805 - - M - - - Glycosyltransferase like family 2
HCBPAAJL_00675 4.69e-158 - - - M - - - transferase activity, transferring glycosyl groups
HCBPAAJL_00677 2.65e-215 - - - S ko:K07011 - ko00000 Glycosyltransferase like family 2
HCBPAAJL_00678 4.02e-192 cps3J - - M - - - Domain of unknown function (DUF4422)
HCBPAAJL_00679 1.77e-159 epsE2 - - M - - - Bacterial sugar transferase
HCBPAAJL_00680 6.17e-191 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 PHP domain protein
HCBPAAJL_00681 5.93e-166 ywqD - - D - - - Capsular exopolysaccharide family
HCBPAAJL_00682 1.01e-193 epsB - - M - - - biosynthesis protein
HCBPAAJL_00683 5.44e-235 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HCBPAAJL_00684 1.42e-286 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCBPAAJL_00685 5.52e-241 - - - S - - - Cysteine-rich secretory protein family
HCBPAAJL_00686 0.0 - - - M - - - Mycoplasma protein of unknown function, DUF285
HCBPAAJL_00687 1.4e-204 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HCBPAAJL_00688 2.99e-176 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HCBPAAJL_00689 7.09e-125 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HCBPAAJL_00690 6.94e-110 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase homologues.
HCBPAAJL_00691 2.96e-56 - - - - - - - -
HCBPAAJL_00692 0.0 - - - S - - - O-antigen ligase like membrane protein
HCBPAAJL_00693 4.7e-143 - - - - - - - -
HCBPAAJL_00694 7.02e-103 nrdI - - F ko:K03647 - ko00000 NrdI Flavodoxin like
HCBPAAJL_00695 2.71e-233 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCBPAAJL_00696 1.36e-105 - - - - - - - -
HCBPAAJL_00697 3.7e-175 - - - S - - - Peptidase_C39 like family
HCBPAAJL_00698 1.47e-70 yitW - - S - - - Iron-sulfur cluster assembly protein
HCBPAAJL_00699 1.08e-62 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HCBPAAJL_00700 1.64e-47 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HCBPAAJL_00701 4.44e-110 - - - S - - - Threonine/Serine exporter, ThrE
HCBPAAJL_00702 3.8e-176 - - - S - - - Putative threonine/serine exporter
HCBPAAJL_00703 0.0 - - - S - - - ABC transporter
HCBPAAJL_00704 3.08e-81 - - - - - - - -
HCBPAAJL_00705 2.7e-59 rimL - - J ko:K03817 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HCBPAAJL_00706 5.01e-293 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HCBPAAJL_00707 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HCBPAAJL_00708 9.86e-59 - - - P ko:K03449 - ko00000,ko02000 transmembrane transport
HCBPAAJL_00709 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HCBPAAJL_00710 1.04e-82 - - - S ko:K07006 - ko00000 Pyridoxamine 5'-phosphate oxidase
HCBPAAJL_00711 6.99e-174 znuB - - U ko:K02075,ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC 3 transport family
HCBPAAJL_00712 6.65e-152 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HCBPAAJL_00713 1.79e-211 - - - P ko:K02077 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HCBPAAJL_00714 7.83e-60 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HCBPAAJL_00715 3e-98 - - - K - - - LytTr DNA-binding domain
HCBPAAJL_00716 4.7e-64 - - - S - - - Protein of unknown function (DUF3021)
HCBPAAJL_00717 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphotransferase System
HCBPAAJL_00718 1.31e-216 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCBPAAJL_00719 3.67e-176 fruR - - K ko:K03436 - ko00000,ko03000 DeoR C terminal sensor domain
HCBPAAJL_00720 5.63e-253 - - - S - - - Fic/DOC family
HCBPAAJL_00721 7.39e-276 natB - - CP ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HCBPAAJL_00722 1.6e-214 natA - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00723 2.89e-12 - - - - - - - -
HCBPAAJL_00724 4.14e-89 - - - - - - - -
HCBPAAJL_00725 6.68e-35 - - - - - - - -
HCBPAAJL_00726 6.32e-42 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HCBPAAJL_00727 9.7e-116 - - - - - - - -
HCBPAAJL_00728 2.26e-29 - - - - - - - -
HCBPAAJL_00733 1.21e-275 blpT - - - - - - -
HCBPAAJL_00734 3.21e-136 mesE - - M ko:K12293,ko:K20345 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 Transport protein ComB
HCBPAAJL_00735 0.0 comA - - V ko:K06147,ko:K06148,ko:K12292,ko:K20344 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko01000,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HCBPAAJL_00738 7.63e-190 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HCBPAAJL_00739 8.09e-298 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HCBPAAJL_00740 2e-06 - - - - - - - -
HCBPAAJL_00743 2.6e-141 - - - - - - - -
HCBPAAJL_00745 2.71e-136 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBPAAJL_00746 5.21e-275 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBPAAJL_00747 2.62e-50 - - - S - - - Enterocin A Immunity
HCBPAAJL_00748 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HCBPAAJL_00749 9.17e-37 - - - - - - - -
HCBPAAJL_00750 1.47e-45 - - - - - - - -
HCBPAAJL_00751 1.4e-69 - - - S - - - Enterocin A Immunity
HCBPAAJL_00752 5.63e-64 - - - S - - - Enterocin A Immunity
HCBPAAJL_00753 7.79e-186 racD 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HCBPAAJL_00754 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCBPAAJL_00755 9.58e-267 - - - T - - - His Kinase A (phosphoacceptor) domain
HCBPAAJL_00756 1.44e-157 vanR - - K - - - response regulator
HCBPAAJL_00757 0.0 ndvA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HCBPAAJL_00758 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00759 1.55e-177 - - - S - - - Protein of unknown function (DUF1129)
HCBPAAJL_00760 1.39e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCBPAAJL_00761 2.22e-59 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HCBPAAJL_00762 2.05e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HCBPAAJL_00763 4.1e-177 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HCBPAAJL_00764 2.79e-188 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HCBPAAJL_00765 3.14e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HCBPAAJL_00766 8.5e-105 cvpA - - S - - - Colicin V production protein
HCBPAAJL_00767 6.64e-233 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCBPAAJL_00768 9.1e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HCBPAAJL_00769 6.34e-127 azr 1.5.1.36 - S ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HCBPAAJL_00770 1.01e-77 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HCBPAAJL_00771 3.82e-25 azo1 1.5.1.36, 1.7.1.6 - S ko:K03206,ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 NADPH-dependent FMN reductase
HCBPAAJL_00772 2.15e-144 - - - K - - - WHG domain
HCBPAAJL_00773 2e-26 - - - - - - - -
HCBPAAJL_00774 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBPAAJL_00775 3.26e-152 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00776 1.43e-231 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HCBPAAJL_00777 1.45e-124 - - - K - - - Bacterial regulatory proteins, tetR family
HCBPAAJL_00778 9.98e-146 - - - G - - - phosphoglycerate mutase
HCBPAAJL_00779 1.19e-179 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HCBPAAJL_00780 4.33e-185 XK27_08125 - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HCBPAAJL_00781 3.44e-153 - - - - - - - -
HCBPAAJL_00782 1.47e-202 - - - C - - - Domain of unknown function (DUF4931)
HCBPAAJL_00783 1.71e-282 - - - S - - - Putative peptidoglycan binding domain
HCBPAAJL_00784 2.13e-36 - - - - - - - -
HCBPAAJL_00785 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HCBPAAJL_00786 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HCBPAAJL_00787 7.67e-80 lysM - - M - - - LysM domain
HCBPAAJL_00788 9.68e-226 - - - - - - - -
HCBPAAJL_00789 3e-133 - - - EGP - - - Major Facilitator Superfamily
HCBPAAJL_00790 8.59e-148 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HCBPAAJL_00792 1.97e-280 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HCBPAAJL_00793 1.53e-118 ymdB - - S - - - Macro domain protein
HCBPAAJL_00794 0.0 nisT - - V ko:K06147,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
HCBPAAJL_00797 2.49e-189 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBPAAJL_00798 2.56e-110 - - - - - - - -
HCBPAAJL_00799 8.05e-197 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_00800 0.0 malF - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_00801 1.35e-282 - - - G ko:K15770 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HCBPAAJL_00802 6e-268 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_00803 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HCBPAAJL_00804 1.23e-150 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HCBPAAJL_00805 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HCBPAAJL_00806 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HCBPAAJL_00807 0.0 malA1 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain
HCBPAAJL_00808 1.82e-276 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBPAAJL_00809 7.43e-229 yvdE - - K - - - helix_turn _helix lactose operon repressor
HCBPAAJL_00810 7.79e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HCBPAAJL_00811 0.0 - - - V ko:K06147,ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HCBPAAJL_00812 4.8e-99 - - - - - - - -
HCBPAAJL_00813 1.06e-20 - - - - - - - -
HCBPAAJL_00814 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCBPAAJL_00815 6.65e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HCBPAAJL_00816 1.23e-83 - - - S - - - Protein conserved in bacteria
HCBPAAJL_00817 9.67e-220 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HCBPAAJL_00818 1.91e-171 cobQ - - S ko:K07009 - ko00000 glutamine amidotransferase
HCBPAAJL_00819 1.96e-108 - - - M - - - NlpC/P60 family
HCBPAAJL_00820 8.16e-212 - - - EG - - - EamA-like transporter family
HCBPAAJL_00821 1.03e-211 - - - EG - - - EamA-like transporter family
HCBPAAJL_00822 1.41e-209 yicL - - EG - - - EamA-like transporter family
HCBPAAJL_00823 7.08e-137 - - - - - - - -
HCBPAAJL_00824 6.33e-74 - - - - - - - -
HCBPAAJL_00825 1.14e-313 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCBPAAJL_00826 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCBPAAJL_00827 2.84e-240 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBPAAJL_00830 1.69e-259 - 4.2.1.126 - S ko:K07106,ko:K09963 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Bacterial protein of unknown function (DUF871)
HCBPAAJL_00831 4.6e-249 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HCBPAAJL_00832 6.65e-153 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HCBPAAJL_00833 1.23e-224 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCBPAAJL_00834 6.09e-152 - - - K - - - Rhodanese Homology Domain
HCBPAAJL_00835 1.75e-10 - - - - - - - -
HCBPAAJL_00836 1.27e-70 - - - CO ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Thioredoxin
HCBPAAJL_00837 1e-305 - - - E - - - amino acid
HCBPAAJL_00838 1.4e-180 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HCBPAAJL_00839 1.84e-314 yifK - - E ko:K03293 - ko00000 Amino acid permease
HCBPAAJL_00840 4.27e-293 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HCBPAAJL_00841 8.71e-157 - - - - - - - -
HCBPAAJL_00842 0.0 - - - L - - - Transposase
HCBPAAJL_00843 1.07e-150 sipS3 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HCBPAAJL_00844 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 AAA domain (Cdc48 subfamily)
HCBPAAJL_00845 4.24e-217 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HCBPAAJL_00846 1e-305 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_00847 8.01e-162 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00848 0.0 ylbB - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HCBPAAJL_00849 5.63e-49 - - - - - - - -
HCBPAAJL_00850 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HCBPAAJL_00851 9.26e-222 lysA2 - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HCBPAAJL_00852 9.09e-164 - - - S - - - Protein of unknown function (DUF975)
HCBPAAJL_00853 2.86e-81 - - - - - - - -
HCBPAAJL_00854 3.4e-228 pbpX2 - - V - - - Beta-lactamase
HCBPAAJL_00855 6.8e-316 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCBPAAJL_00856 2.46e-48 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBPAAJL_00857 3.35e-310 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HCBPAAJL_00858 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCBPAAJL_00859 2.17e-25 - - - S - - - D-Ala-teichoic acid biosynthesis protein
HCBPAAJL_00860 2.18e-53 - - - - - - - -
HCBPAAJL_00861 8.03e-278 - - - S - - - Membrane
HCBPAAJL_00862 1.97e-107 ykuL - - S - - - (CBS) domain
HCBPAAJL_00863 0.0 cadA - - P - - - P-type ATPase
HCBPAAJL_00864 4.69e-262 napA - - P - - - Sodium/hydrogen exchanger family
HCBPAAJL_00865 2.82e-105 - - - S - - - Putative adhesin
HCBPAAJL_00866 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC transporter transmembrane region
HCBPAAJL_00867 1.57e-197 mutR - - K - - - Helix-turn-helix XRE-family like proteins
HCBPAAJL_00868 5.7e-125 - - - M - - - CHAP domain
HCBPAAJL_00869 1.4e-88 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBPAAJL_00870 2.41e-155 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBPAAJL_00871 3.39e-253 - - - S - - - DUF218 domain
HCBPAAJL_00872 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00873 4.51e-134 - - - S - - - ECF transporter, substrate-specific component
HCBPAAJL_00874 1.21e-236 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
HCBPAAJL_00875 9.41e-257 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein PnrA-like
HCBPAAJL_00876 0.0 mglA 3.6.3.17 - S ko:K02056,ko:K06400 - ko00000,ko00002,ko01000,ko02000 ABC transporter
HCBPAAJL_00877 9.19e-266 mglC - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HCBPAAJL_00878 4.74e-217 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HCBPAAJL_00879 1.25e-204 - - - S - - - Aldo/keto reductase family
HCBPAAJL_00880 1.19e-175 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCBPAAJL_00881 1.63e-152 dak 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HCBPAAJL_00882 6.91e-165 dgk2 2.7.1.76 - F ko:K10353 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 deoxynucleoside kinase
HCBPAAJL_00883 3.03e-187 - - - S - - - haloacid dehalogenase-like hydrolase
HCBPAAJL_00884 3.53e-294 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HCBPAAJL_00885 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HCBPAAJL_00886 2.29e-166 - - - K - - - helix_turn_helix, mercury resistance
HCBPAAJL_00887 4.08e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HCBPAAJL_00888 3.14e-226 pepL 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HCBPAAJL_00889 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HCBPAAJL_00890 8.03e-289 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HCBPAAJL_00891 2.47e-32 - - - - - - - -
HCBPAAJL_00892 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HCBPAAJL_00893 6.78e-100 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Penicillinase repressor
HCBPAAJL_00894 1.77e-85 - - - S - - - Cupredoxin-like domain
HCBPAAJL_00895 1.09e-65 - - - S - - - Cupredoxin-like domain
HCBPAAJL_00896 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HCBPAAJL_00897 2.91e-234 - - - S - - - DUF218 domain
HCBPAAJL_00898 6.11e-168 - - - S - - - Mitochondrial biogenesis AIM24
HCBPAAJL_00899 6.65e-153 crp2 - - K ko:K10914,ko:K21562 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 helix_turn_helix, cAMP Regulatory protein
HCBPAAJL_00900 1.78e-26 - - - - - - - -
HCBPAAJL_00901 5.17e-273 - - - - - - - -
HCBPAAJL_00902 0.0 eriC - - P ko:K03281 - ko00000 chloride
HCBPAAJL_00903 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCBPAAJL_00904 0.0 pox1 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HCBPAAJL_00905 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCBPAAJL_00906 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCBPAAJL_00907 2.31e-199 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCBPAAJL_00908 1.87e-81 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCBPAAJL_00909 3.26e-23 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HCBPAAJL_00910 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCBPAAJL_00911 1.46e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCBPAAJL_00912 6.15e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HCBPAAJL_00913 3.1e-269 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCBPAAJL_00914 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBPAAJL_00915 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCBPAAJL_00916 9.55e-66 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HCBPAAJL_00917 8.43e-110 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCBPAAJL_00918 1.89e-47 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCBPAAJL_00919 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HCBPAAJL_00920 6.96e-100 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HCBPAAJL_00921 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HCBPAAJL_00922 1e-220 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, phosphonate, periplasmic substrate-binding protein
HCBPAAJL_00923 1.38e-225 degV1 - - S - - - DegV family
HCBPAAJL_00924 1.09e-215 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HCBPAAJL_00925 1.38e-33 - - - S - - - CsbD-like
HCBPAAJL_00926 1.47e-41 - - - S - - - Transglycosylase associated protein
HCBPAAJL_00927 1.25e-303 - - - I - - - Protein of unknown function (DUF2974)
HCBPAAJL_00929 7.47e-133 cadD - - P - - - Cadmium resistance transporter
HCBPAAJL_00930 2.41e-77 - - - K ko:K21903 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HCBPAAJL_00931 2.93e-235 - - - - - - - -
HCBPAAJL_00932 1.08e-71 - - - - - - - -
HCBPAAJL_00933 7.23e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HCBPAAJL_00934 4.15e-120 - - - - - - - -
HCBPAAJL_00935 1.16e-234 - - - EP - - - Plasmid replication protein
HCBPAAJL_00936 1.45e-42 - - - - - - - -
HCBPAAJL_00937 8.39e-299 - - - L - - - Belongs to the 'phage' integrase family
HCBPAAJL_00938 4.37e-43 - - - - - - - -
HCBPAAJL_00939 4.41e-92 doc - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
HCBPAAJL_00940 1.63e-27 - - - S - - - Protein of unknown function (DUF3923)
HCBPAAJL_00943 2.01e-205 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HCBPAAJL_00944 0.0 - - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBPAAJL_00945 1.5e-295 - - - S - - - LPXTG cell wall anchor motif
HCBPAAJL_00946 1.4e-196 - - - S - - - Putative ABC-transporter type IV
HCBPAAJL_00947 2.37e-129 - - - S - - - Cob(I)alamin adenosyltransferase
HCBPAAJL_00948 6.12e-112 - - - S ko:K16927 - ko00000,ko00002,ko02000 ECF transporter, substrate-specific component
HCBPAAJL_00949 9.95e-75 - - - S - - - Domain of unknown function (DUF4430)
HCBPAAJL_00950 0.0 rtpR 1.17.4.2 - F ko:K00527 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 ribonucleoside-triphosphate reductase activity
HCBPAAJL_00951 2e-223 ydbI - - K - - - AI-2E family transporter
HCBPAAJL_00952 2.37e-135 - - - E - - - GDSL-like Lipase/Acylhydrolase
HCBPAAJL_00953 9.67e-22 - - - - - - - -
HCBPAAJL_00954 2.79e-313 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HCBPAAJL_00955 6.35e-69 - - - - - - - -
HCBPAAJL_00956 8.29e-174 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_00957 3.51e-170 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HCBPAAJL_00958 3.82e-229 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HCBPAAJL_00959 1.29e-178 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HCBPAAJL_00960 0.0 fusA1 - - J - - - elongation factor G
HCBPAAJL_00961 1.99e-195 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HCBPAAJL_00962 9.66e-41 - - - S - - - endonuclease exonuclease phosphatase family protein
HCBPAAJL_00963 1.63e-172 - - - S - - - endonuclease exonuclease phosphatase family protein
HCBPAAJL_00964 8.28e-15 - - - S - - - interspecies interaction between organisms
HCBPAAJL_00965 5.27e-247 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBPAAJL_00966 3.08e-205 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HCBPAAJL_00967 0.0 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 amino acid
HCBPAAJL_00968 0.0 - - - L - - - Helicase C-terminal domain protein
HCBPAAJL_00969 3.12e-273 pbpX1 - - V - - - Beta-lactamase
HCBPAAJL_00970 6.19e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCBPAAJL_00972 3.73e-65 - - - K - - - LysR substrate binding domain
HCBPAAJL_00973 4.38e-74 - - - S - - - FMN_bind
HCBPAAJL_00974 1.87e-292 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HCBPAAJL_00975 3.17e-149 - - - K - - - Transcriptional regulator, LysR family
HCBPAAJL_00976 2.5e-51 - - - S - - - Cytochrome B5
HCBPAAJL_00977 2.27e-214 arbZ - - I - - - Phosphate acyltransferases
HCBPAAJL_00978 1.34e-235 - - - M - - - Glycosyl transferase family 8
HCBPAAJL_00979 1.07e-238 - - - M - - - Glycosyl transferase family 8
HCBPAAJL_00980 6.45e-204 arbx - - M - - - Glycosyl transferase family 8
HCBPAAJL_00981 1.11e-191 - - - I - - - Acyl-transferase
HCBPAAJL_00982 8.36e-102 - - - - - - - -
HCBPAAJL_00983 0.0 - - - P ko:K06148 - ko00000,ko02000 ABC transporter
HCBPAAJL_00984 0.0 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HCBPAAJL_00985 0.0 - - - L - - - Transposase
HCBPAAJL_00988 9.77e-170 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HCBPAAJL_00989 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HCBPAAJL_00990 0.0 yycH - - S - - - YycH protein
HCBPAAJL_00991 3.54e-190 yycI - - S - - - YycH protein
HCBPAAJL_00992 9.1e-193 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HCBPAAJL_00993 2.7e-257 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HCBPAAJL_00994 2.48e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCBPAAJL_00995 1.51e-194 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBPAAJL_00997 0.0 - - - S - - - CAAX protease self-immunity
HCBPAAJL_00998 1.98e-26 - - - - - - - -
HCBPAAJL_00999 1.09e-157 - - - - - - - -
HCBPAAJL_01000 8e-226 pepI 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HCBPAAJL_01001 6.92e-130 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HCBPAAJL_01002 0.0 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_01003 2.11e-222 - - - K - - - helix_turn_helix, arabinose operon control protein
HCBPAAJL_01004 9.9e-209 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HCBPAAJL_01005 1.43e-125 lemA - - S ko:K03744 - ko00000 LemA family
HCBPAAJL_01006 4.01e-218 ysdE - - P - - - Citrate transporter
HCBPAAJL_01007 3.96e-05 ysdE - - P - - - Citrate transporter
HCBPAAJL_01008 7.83e-91 - - - S - - - Iron-sulphur cluster biosynthesis
HCBPAAJL_01009 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HCBPAAJL_01010 9.69e-25 - - - - - - - -
HCBPAAJL_01011 2.14e-197 - - - - - - - -
HCBPAAJL_01013 1.08e-288 ydaM - - M - - - Glycosyl transferase family group 2
HCBPAAJL_01014 2.11e-271 - - - G - - - Glycosyl hydrolases family 8
HCBPAAJL_01015 1.07e-157 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HCBPAAJL_01016 2.73e-206 - - - L - - - HNH nucleases
HCBPAAJL_01017 1.63e-233 yhaH - - S - - - Protein of unknown function (DUF805)
HCBPAAJL_01018 2.21e-177 glnQ - - E ko:K17076 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_01019 0.0 XK27_05795 - - P ko:K17073,ko:K17074 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01020 3.08e-159 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HCBPAAJL_01021 2.29e-85 yeaO - - S - - - Protein of unknown function, DUF488
HCBPAAJL_01022 9.33e-180 terC - - P - - - Integral membrane protein TerC family
HCBPAAJL_01023 2.57e-171 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HCBPAAJL_01024 9.36e-111 - - - - - - - -
HCBPAAJL_01025 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCBPAAJL_01026 1.45e-231 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HCBPAAJL_01027 2.82e-183 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBPAAJL_01028 5.06e-182 - - - S - - - Protein of unknown function (DUF1002)
HCBPAAJL_01029 2.63e-204 - - - M - - - Glycosyltransferase like family 2
HCBPAAJL_01030 1.07e-163 - - - S - - - Alpha/beta hydrolase family
HCBPAAJL_01031 1.02e-191 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBPAAJL_01032 1.33e-75 - - - - - - - -
HCBPAAJL_01033 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HCBPAAJL_01034 2.83e-62 - - - - - - - -
HCBPAAJL_01035 5.31e-58 - 3.6.4.12 - - ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 -
HCBPAAJL_01036 1.3e-99 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative ATP-dependent DNA helicase recG C-terminal
HCBPAAJL_01037 1.51e-234 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBPAAJL_01038 1.19e-160 - - - K - - - Bacterial regulatory proteins, tetR family
HCBPAAJL_01039 2.93e-173 - - - - - - - -
HCBPAAJL_01040 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01041 7.42e-173 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_01042 1.96e-293 - - - S - - - Cysteine-rich secretory protein family
HCBPAAJL_01043 7.25e-265 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HCBPAAJL_01044 1.49e-136 - - - - - - - -
HCBPAAJL_01045 9.78e-258 yibE - - S - - - overlaps another CDS with the same product name
HCBPAAJL_01046 1.71e-170 yibF - - S - - - overlaps another CDS with the same product name
HCBPAAJL_01047 7.56e-205 - - - I - - - alpha/beta hydrolase fold
HCBPAAJL_01048 0.0 - - - G - - - Belongs to the glycosyl hydrolase 31 family
HCBPAAJL_01049 8.53e-292 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCBPAAJL_01050 2.9e-116 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HCBPAAJL_01051 1.74e-112 - 2.7.1.200, 2.7.1.204 - G ko:K02773,ko:K20112 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCBPAAJL_01052 8.74e-192 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HCBPAAJL_01053 3.95e-113 usp5 - - T - - - universal stress protein
HCBPAAJL_01054 7.56e-214 phnD - - P ko:K02044 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphonate ABC transporter
HCBPAAJL_01055 4.46e-180 phnC 3.6.3.28 - P ko:K02041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCBPAAJL_01056 2.84e-171 phnB - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_01057 6.38e-191 - - - P ko:K02042 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_01058 7.66e-141 tag 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HCBPAAJL_01059 3.65e-109 - - - - - - - -
HCBPAAJL_01060 0.0 - - - S - - - Calcineurin-like phosphoesterase
HCBPAAJL_01061 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HCBPAAJL_01062 0.0 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HCBPAAJL_01063 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HCBPAAJL_01064 1.29e-178 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCBPAAJL_01065 1.6e-127 yitW - - S - - - Iron-sulfur cluster assembly protein
HCBPAAJL_01066 4.3e-297 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HCBPAAJL_01067 1.88e-292 yttB - - EGP - - - Major Facilitator
HCBPAAJL_01068 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HCBPAAJL_01069 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HCBPAAJL_01070 6.3e-91 - - - - - - - -
HCBPAAJL_01071 2.15e-21 - - - - - - - -
HCBPAAJL_01072 3.76e-289 - - - S - - - SLAP domain
HCBPAAJL_01073 4.97e-81 - 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 6-pyruvoyl tetrahydropterin synthase
HCBPAAJL_01074 0.0 icaA - - M - - - Glycosyl transferase family group 2
HCBPAAJL_01075 2.97e-234 - - - - - - - -
HCBPAAJL_01076 8.52e-304 - - - S - - - SLAP domain
HCBPAAJL_01077 2.53e-283 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCBPAAJL_01078 7.59e-269 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HCBPAAJL_01079 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HCBPAAJL_01080 6.61e-230 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HCBPAAJL_01081 4.62e-181 - - - - - - - -
HCBPAAJL_01082 2.12e-176 - - - - - - - -
HCBPAAJL_01083 1.84e-170 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCBPAAJL_01084 8.51e-143 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCBPAAJL_01085 1.96e-132 - - - G - - - Aldose 1-epimerase
HCBPAAJL_01086 1.34e-259 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HCBPAAJL_01087 2.73e-146 plsY1 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCBPAAJL_01088 0.0 XK27_08315 - - M - - - Sulfatase
HCBPAAJL_01089 0.0 - - - S - - - Fibronectin type III domain
HCBPAAJL_01090 6.28e-310 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCBPAAJL_01091 1.02e-74 - - - - - - - -
HCBPAAJL_01093 0.0 pepC1 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HCBPAAJL_01094 1.16e-162 ypgQ - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBPAAJL_01095 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HCBPAAJL_01096 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substratebinding protein
HCBPAAJL_01097 8.86e-267 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCBPAAJL_01098 5.46e-191 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBPAAJL_01099 1.92e-240 oppC - - EP ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCBPAAJL_01100 1.9e-256 oppD - - P ko:K02031,ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_01101 1.87e-221 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_01102 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HCBPAAJL_01103 1.5e-96 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HCBPAAJL_01104 6.92e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCBPAAJL_01105 1.09e-148 - - - - - - - -
HCBPAAJL_01107 1.21e-146 - - - E - - - Belongs to the SOS response-associated peptidase family
HCBPAAJL_01108 2.35e-244 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HCBPAAJL_01109 2.69e-119 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 MafB19-like deaminase
HCBPAAJL_01110 1.25e-142 - - - S ko:K06872 - ko00000 TPM domain
HCBPAAJL_01111 8.2e-140 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HCBPAAJL_01112 0.0 mgtA 3.6.3.2 - P ko:K01531 - ko00000,ko01000 COG0474 Cation transport ATPase
HCBPAAJL_01113 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCBPAAJL_01114 2.33e-190 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HCBPAAJL_01115 1.63e-124 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCBPAAJL_01116 4.9e-207 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCBPAAJL_01117 9.99e-53 veg - - S - - - Biofilm formation stimulator VEG
HCBPAAJL_01118 4.31e-192 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HCBPAAJL_01119 0.0 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCBPAAJL_01120 1.4e-116 - - - S - - - SLAP domain
HCBPAAJL_01121 4.55e-117 - - - S - - - SLAP domain
HCBPAAJL_01122 1.48e-114 - - - - - - - -
HCBPAAJL_01123 0.0 - - - S - - - SLAP domain
HCBPAAJL_01124 6.58e-227 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCBPAAJL_01125 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_01126 3.82e-167 yecA - - K - - - Helix-turn-helix domain, rpiR family
HCBPAAJL_01127 0.0 - - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_01128 4.58e-216 - - - GK - - - ROK family
HCBPAAJL_01129 4.88e-59 - - - - - - - -
HCBPAAJL_01130 0.0 - - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HCBPAAJL_01131 4.39e-88 - - - S - - - Domain of unknown function (DUF1934)
HCBPAAJL_01132 1.11e-96 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCBPAAJL_01133 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCBPAAJL_01134 6.32e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCBPAAJL_01135 4.42e-142 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBPAAJL_01136 1.59e-205 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HCBPAAJL_01137 7.87e-207 msmR - - K - - - AraC-like ligand binding domain
HCBPAAJL_01138 1.87e-137 ybbB - - S - - - Protein of unknown function (DUF1211)
HCBPAAJL_01139 1.21e-285 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HCBPAAJL_01140 5.8e-137 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCBPAAJL_01141 1.04e-173 - - - K - - - DNA-binding helix-turn-helix protein
HCBPAAJL_01142 3.77e-220 - - - K - - - Helix-turn-helix
HCBPAAJL_01143 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HCBPAAJL_01144 7.77e-199 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_01145 3.12e-191 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HCBPAAJL_01146 1.03e-96 - - - K - - - LytTr DNA-binding domain
HCBPAAJL_01147 1.16e-63 - - - S - - - Protein of unknown function (DUF3021)
HCBPAAJL_01148 7.88e-116 - - - K - - - Acetyltransferase (GNAT) domain
HCBPAAJL_01149 9.09e-173 XK27_07210 - - S - - - B3 4 domain
HCBPAAJL_01150 2.07e-117 - - - P - - - Belongs to the major facilitator superfamily
HCBPAAJL_01151 2.89e-44 - - - P - - - Belongs to the major facilitator superfamily
HCBPAAJL_01152 5.49e-42 - - - - - - - -
HCBPAAJL_01153 3.18e-106 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCBPAAJL_01154 6.74e-39 - - - K ko:K12410 - ko00000,ko01000 NAD+ binding
HCBPAAJL_01155 4.62e-13 - - - P - - - Voltage gated chloride channel
HCBPAAJL_01156 7.47e-126 - - - - - - - -
HCBPAAJL_01157 8.2e-68 - - - - - - - -
HCBPAAJL_01158 4.88e-59 - - - - - - - -
HCBPAAJL_01159 9.39e-296 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCBPAAJL_01160 5.58e-206 - - - E - - - amino acid
HCBPAAJL_01161 4.13e-177 - - - E - - - amino acid
HCBPAAJL_01162 9.8e-204 supH 3.1.3.102, 3.1.3.104, 3.1.3.23 - G ko:K07757,ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HCBPAAJL_01163 0.0 dexB 3.2.1.70 - G ko:K01215 - ko00000,ko01000 Alpha amylase, catalytic domain protein
HCBPAAJL_01164 5.28e-53 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HCBPAAJL_01165 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCBPAAJL_01166 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCBPAAJL_01167 3.83e-79 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCBPAAJL_01168 1.62e-276 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCBPAAJL_01169 1.23e-166 - - - S - - - (CBS) domain
HCBPAAJL_01170 1.98e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HCBPAAJL_01171 6.58e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCBPAAJL_01172 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCBPAAJL_01173 1.79e-46 yabO - - J - - - S4 domain protein
HCBPAAJL_01174 1.03e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HCBPAAJL_01175 3.95e-82 - - - J ko:K07571 - ko00000 S1 RNA binding domain
HCBPAAJL_01176 5.11e-307 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCBPAAJL_01177 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCBPAAJL_01178 6.77e-215 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCBPAAJL_01179 3.5e-249 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCBPAAJL_01180 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HCBPAAJL_01184 1.16e-107 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HCBPAAJL_01185 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCBPAAJL_01186 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBPAAJL_01187 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBPAAJL_01188 6.6e-159 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HCBPAAJL_01189 2.09e-91 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCBPAAJL_01190 6.89e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCBPAAJL_01191 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCBPAAJL_01192 6.34e-66 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HCBPAAJL_01193 6.64e-146 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCBPAAJL_01194 1.91e-137 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HCBPAAJL_01195 3.57e-62 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCBPAAJL_01196 9.85e-199 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCBPAAJL_01197 1.34e-61 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCBPAAJL_01198 9.07e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCBPAAJL_01199 7.15e-156 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCBPAAJL_01200 9.64e-100 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCBPAAJL_01201 1.45e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HCBPAAJL_01202 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCBPAAJL_01203 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCBPAAJL_01204 6.92e-45 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCBPAAJL_01205 1.23e-123 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCBPAAJL_01206 1e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBPAAJL_01207 2.28e-89 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCBPAAJL_01208 2.5e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCBPAAJL_01209 4.84e-73 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCBPAAJL_01210 5.3e-110 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCBPAAJL_01211 1.1e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HCBPAAJL_01212 2.45e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HCBPAAJL_01213 3.59e-301 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCBPAAJL_01214 1.29e-155 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCBPAAJL_01215 3.13e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCBPAAJL_01216 4.63e-22 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HCBPAAJL_01217 2.07e-73 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCBPAAJL_01218 3.95e-82 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCBPAAJL_01219 2.55e-218 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCBPAAJL_01220 1.57e-80 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HCBPAAJL_01221 4.16e-198 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBPAAJL_01222 4.04e-206 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBPAAJL_01223 1.74e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCBPAAJL_01224 4.17e-192 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCBPAAJL_01225 1.6e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCBPAAJL_01226 8.28e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HCBPAAJL_01227 7.71e-255 - - - L - - - Phage integrase family
HCBPAAJL_01228 4.24e-37 - - - - - - - -
HCBPAAJL_01229 1.31e-270 - - - EP - - - Plasmid replication protein
HCBPAAJL_01230 1.77e-61 - - - - - - - -
HCBPAAJL_01231 2.52e-264 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HCBPAAJL_01232 1.48e-69 - - - - - - - -
HCBPAAJL_01234 0.0 yeeA - - V - - - Type II restriction enzyme, methylase subunits
HCBPAAJL_01235 1.53e-85 - - - S - - - YjcQ protein
HCBPAAJL_01237 5.27e-16 - - - - - - - -
HCBPAAJL_01238 3.63e-141 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HCBPAAJL_01239 4.67e-154 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HCBPAAJL_01240 8.09e-160 - - - S ko:K07090 - ko00000 membrane transporter protein
HCBPAAJL_01241 6.91e-164 - - - G - - - Belongs to the phosphoglycerate mutase family
HCBPAAJL_01242 5.3e-209 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HCBPAAJL_01243 1.14e-27 - - - - - - - -
HCBPAAJL_01244 1.27e-104 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCBPAAJL_01245 9.84e-236 - - - S - - - AAA domain
HCBPAAJL_01246 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HCBPAAJL_01247 9.95e-70 - - - - - - - -
HCBPAAJL_01248 1.82e-131 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HCBPAAJL_01249 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCBPAAJL_01250 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCBPAAJL_01251 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HCBPAAJL_01252 6.01e-99 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCBPAAJL_01253 4.31e-179 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCBPAAJL_01254 2.91e-121 comX - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HCBPAAJL_01255 2.41e-45 - - - - - - - -
HCBPAAJL_01256 6.48e-148 - - - - - - - -
HCBPAAJL_01257 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HCBPAAJL_01258 1.22e-220 - - - K - - - helix_turn_helix, arabinose operon control protein
HCBPAAJL_01259 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCBPAAJL_01260 1.72e-33 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCBPAAJL_01261 3.66e-132 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HCBPAAJL_01262 2.69e-90 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCBPAAJL_01263 1.5e-160 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCBPAAJL_01264 2.83e-203 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HCBPAAJL_01265 1.8e-223 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HCBPAAJL_01266 4.47e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HCBPAAJL_01267 4.47e-186 pstB2 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBPAAJL_01268 5.67e-180 pstB1 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCBPAAJL_01269 1.74e-152 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HCBPAAJL_01270 3.62e-268 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HCBPAAJL_01271 1.86e-38 - - - - - - - -
HCBPAAJL_01272 2.15e-110 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCBPAAJL_01273 9.31e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCBPAAJL_01274 3.83e-167 - 2.1.1.172 - J ko:K00564,ko:K10716 - ko00000,ko01000,ko02000,ko03009 Ion channel
HCBPAAJL_01275 1.25e-147 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HCBPAAJL_01276 4.9e-33 - - - - - - - -
HCBPAAJL_01277 9.21e-120 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCBPAAJL_01278 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCBPAAJL_01279 1.71e-287 - - - L ko:K07496 - ko00000 Putative transposase DNA-binding domain
HCBPAAJL_01280 2.2e-68 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCBPAAJL_01281 4.56e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCBPAAJL_01282 1.18e-46 - - - S - - - Protein of unknown function (DUF2508)
HCBPAAJL_01283 1.69e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCBPAAJL_01284 1.85e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
HCBPAAJL_01285 5.91e-199 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HCBPAAJL_01286 2.65e-80 yabA - - L - - - Involved in initiation control of chromosome replication
HCBPAAJL_01287 9.46e-200 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCBPAAJL_01288 1.29e-182 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HCBPAAJL_01289 6.76e-114 - - - S - - - ECF transporter, substrate-specific component
HCBPAAJL_01290 8.02e-172 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HCBPAAJL_01291 1.49e-138 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HCBPAAJL_01292 5.62e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCBPAAJL_01293 9.05e-170 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HCBPAAJL_01294 7.2e-235 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HCBPAAJL_01295 4.46e-165 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HCBPAAJL_01296 1.38e-298 bbsF_1 2.8.3.19 - C ko:K18702 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCBPAAJL_01297 0.0 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCBPAAJL_01298 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HCBPAAJL_01299 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HCBPAAJL_01300 1.24e-145 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCBPAAJL_01301 6.41e-236 scrR - - K ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HCBPAAJL_01302 0.0 scrB 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HCBPAAJL_01303 0.0 scrA 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_01304 4.92e-107 - - - - - - - -
HCBPAAJL_01305 1.33e-100 - - - K - - - LytTr DNA-binding domain
HCBPAAJL_01306 2.29e-175 - - - S - - - membrane
HCBPAAJL_01307 2.22e-60 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCBPAAJL_01308 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCBPAAJL_01309 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCBPAAJL_01310 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCBPAAJL_01311 2.35e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCBPAAJL_01312 1.61e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCBPAAJL_01313 2.41e-83 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HCBPAAJL_01314 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCBPAAJL_01315 1.32e-255 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCBPAAJL_01316 9.43e-233 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HCBPAAJL_01317 8.26e-316 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCBPAAJL_01318 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCBPAAJL_01319 5.32e-57 yrzL - - S - - - Belongs to the UPF0297 family
HCBPAAJL_01320 3.27e-96 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCBPAAJL_01321 2.03e-67 yrzB - - S - - - Belongs to the UPF0473 family
HCBPAAJL_01322 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCBPAAJL_01323 1.54e-71 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HCBPAAJL_01324 1.46e-70 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCBPAAJL_01325 2.57e-91 yslB - - S - - - Protein of unknown function (DUF2507)
HCBPAAJL_01326 1.33e-186 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HCBPAAJL_01327 1.42e-143 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCBPAAJL_01328 3.18e-165 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HCBPAAJL_01329 2.09e-23 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCBPAAJL_01330 1.37e-74 - - - - - - - -
HCBPAAJL_01331 4.1e-275 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HCBPAAJL_01332 4.5e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HCBPAAJL_01333 0.0 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HCBPAAJL_01334 2.5e-74 - - - - - - - -
HCBPAAJL_01335 0.0 sasH 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HCBPAAJL_01336 6.99e-134 yutD - - S - - - Protein of unknown function (DUF1027)
HCBPAAJL_01337 1.9e-186 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCBPAAJL_01338 3.19e-139 - - - S - - - Protein of unknown function (DUF1461)
HCBPAAJL_01339 1.45e-151 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HCBPAAJL_01340 4.65e-193 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HCBPAAJL_01359 1.98e-96 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HCBPAAJL_01360 0.0 - - - L - - - Helicase C-terminal domain protein
HCBPAAJL_01361 3.83e-61 - - - L - - - Helicase C-terminal domain protein
HCBPAAJL_01373 2.24e-284 - 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyl transferase 4-like domain
HCBPAAJL_01374 1.5e-255 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HCBPAAJL_01375 5.18e-228 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCBPAAJL_01376 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCBPAAJL_01377 5.29e-40 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HCBPAAJL_01378 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCBPAAJL_01379 1.99e-99 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCBPAAJL_01381 1.36e-241 manL 2.7.1.191 - G ko:K02793,ko:K02794 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HCBPAAJL_01382 1.67e-181 manY - - G ko:K02746,ko:K02795 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system
HCBPAAJL_01383 1.18e-225 manN - - G ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 system, mannose fructose sorbose family IID component
HCBPAAJL_01384 2.86e-85 - - - S - - - Domain of unknown function (DUF956)
HCBPAAJL_01385 7.93e-206 - - - K - - - Transcriptional regulator
HCBPAAJL_01386 3.62e-89 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HCBPAAJL_01387 2.27e-315 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HCBPAAJL_01388 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HCBPAAJL_01389 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCBPAAJL_01390 1.47e-285 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBPAAJL_01391 1.63e-175 - 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 Carboxymuconolactone decarboxylase family
HCBPAAJL_01392 8.15e-94 apfA 3.6.1.61 - F ko:K18445 ko00230,map00230 ko00000,ko00001,ko01000 Nudix hydrolase
HCBPAAJL_01393 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Phosphoenolpyruvate carboxykinase
HCBPAAJL_01394 0.0 - - - S - - - TerB-C domain
HCBPAAJL_01395 0.0 - - - P - - - P-loop Domain of unknown function (DUF2791)
HCBPAAJL_01396 0.0 - - - L ko:K03724 - ko00000,ko01000,ko03400 DEAD DEAH box helicase
HCBPAAJL_01397 4.47e-81 - - - - - - - -
HCBPAAJL_01398 1.14e-294 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HCBPAAJL_01399 8.42e-187 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HCBPAAJL_01401 0.0 - - - L - - - Type III restriction enzyme, res subunit
HCBPAAJL_01402 0.0 - - - S - - - AAA ATPase domain
HCBPAAJL_01403 1.41e-208 - 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 DNA methyltransferase
HCBPAAJL_01404 8.37e-161 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HCBPAAJL_01406 8.66e-76 - - - - - - - -
HCBPAAJL_01407 2.66e-270 - - - D - - - COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HCBPAAJL_01409 3.69e-244 - - - EP - - - Plasmid replication protein
HCBPAAJL_01410 6.89e-06 - - - - - - - -
HCBPAAJL_01411 2.79e-296 - - - L - - - Belongs to the 'phage' integrase family
HCBPAAJL_01412 1.27e-90 - - - S - - - Iron-sulphur cluster biosynthesis
HCBPAAJL_01413 3.99e-45 - - - - - - - -
HCBPAAJL_01414 3.99e-88 - - - - - - - -
HCBPAAJL_01415 1.48e-219 pphA 3.1.3.16 - T ko:K07313 - ko00000,ko01000 Calcineurin-like phosphoesterase
HCBPAAJL_01416 2.6e-19 - - - - - - - -
HCBPAAJL_01417 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_01418 4.35e-207 - - - O - - - protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
HCBPAAJL_01419 2.62e-111 - - - M - - - LysM domain protein
HCBPAAJL_01420 3.81e-253 - - - D - - - nuclear chromosome segregation
HCBPAAJL_01421 1e-142 - - - G - - - Phosphoglycerate mutase family
HCBPAAJL_01422 2.57e-139 - - - G - - - Histidine phosphatase superfamily (branch 1)
HCBPAAJL_01423 9.82e-156 - - - G - - - Antibiotic biosynthesis monooxygenase
HCBPAAJL_01424 9.11e-69 glpQ1 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HCBPAAJL_01425 7.11e-236 lacI - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HCBPAAJL_01426 0.0 - - - G ko:K02027,ko:K10120 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HCBPAAJL_01427 1.78e-209 - - - P ko:K10121 - ko00000,ko00002,ko02000 ABC-type sugar transport systems, permease components
HCBPAAJL_01428 2.93e-199 msmG - - G ko:K02026,ko:K10122 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HCBPAAJL_01429 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 32
HCBPAAJL_01430 8.89e-270 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HCBPAAJL_01431 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HCBPAAJL_01432 3.18e-92 - - - EGP - - - Major Facilitator
HCBPAAJL_01434 6.76e-227 pfoSR - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HCBPAAJL_01435 0.0 slpX - - S - - - SLAP domain
HCBPAAJL_01438 5.81e-272 - - - - - - - -
HCBPAAJL_01439 1.33e-160 gntR1 - - K ko:K03710 - ko00000,ko03000 UTRA
HCBPAAJL_01440 2.13e-92 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Glycerol-3-phosphate cytidylyltransferase
HCBPAAJL_01441 1.39e-171 tagA 2.4.1.187 GT26 F ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCBPAAJL_01442 1.85e-264 - - - M - - - Glycosyl transferases group 1
HCBPAAJL_01443 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCBPAAJL_01444 5.7e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCBPAAJL_01445 0.0 pacL 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HCBPAAJL_01446 3.89e-288 - - - M - - - CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCBPAAJL_01447 0.0 epsU - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HCBPAAJL_01448 8.44e-177 - - - M - - - Glycosyltransferase sugar-binding region containing DXD motif
HCBPAAJL_01449 6.32e-83 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HCBPAAJL_01451 1.02e-146 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HCBPAAJL_01452 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HCBPAAJL_01453 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCBPAAJL_01454 7.29e-267 camS - - S - - - sex pheromone
HCBPAAJL_01455 4.46e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBPAAJL_01456 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCBPAAJL_01457 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCBPAAJL_01458 2.37e-220 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HCBPAAJL_01459 8.38e-144 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HCBPAAJL_01460 4.94e-75 - - - - - - - -
HCBPAAJL_01461 1.28e-310 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HCBPAAJL_01462 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBPAAJL_01463 4.2e-30 - - - - - - - -
HCBPAAJL_01464 1.48e-82 - - - - - - - -
HCBPAAJL_01465 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HCBPAAJL_01466 5.51e-46 - - - C - - - Heavy-metal-associated domain
HCBPAAJL_01467 1.05e-124 dpsB - - P - - - Belongs to the Dps family
HCBPAAJL_01468 9.1e-148 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HCBPAAJL_01469 5.16e-146 ung2 - - L - - - Uracil-DNA glycosylase
HCBPAAJL_01470 3.15e-62 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
HCBPAAJL_01471 2.43e-76 - 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Asp/Glu/Hydantoin racemase
HCBPAAJL_01472 2.98e-246 - - - L ko:K06400 - ko00000 Recombinase
HCBPAAJL_01473 3.28e-122 - - - L - - - Resolvase, N terminal domain
HCBPAAJL_01474 9.05e-231 - - - L - - - Recombinase zinc beta ribbon domain
HCBPAAJL_01475 3.49e-123 - - - K - - - Acetyltransferase (GNAT) domain
HCBPAAJL_01480 0.0 qacA - - EGP - - - Major Facilitator
HCBPAAJL_01481 1.88e-174 - - - S - - - CAAX protease self-immunity
HCBPAAJL_01482 1.25e-118 - - - K - - - Bacterial regulatory proteins, tetR family
HCBPAAJL_01483 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HCBPAAJL_01484 3.79e-101 - - - K - - - acetyltransferase
HCBPAAJL_01485 4.73e-206 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HCBPAAJL_01486 5.13e-141 - - - V ko:K06148 - ko00000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HCBPAAJL_01487 5.81e-165 XK27_08575 - - V ko:K06148 - ko00000,ko02000 cysteine transport
HCBPAAJL_01488 5.36e-305 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HCBPAAJL_01489 1.39e-118 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCBPAAJL_01490 3.27e-110 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HCBPAAJL_01491 2.03e-67 - 3.1.3.102, 3.1.3.104 - Q ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 phosphatase activity
HCBPAAJL_01492 0.0 qacA - - EGP - - - Major Facilitator
HCBPAAJL_01493 3.81e-274 pmrA - - EGP ko:K08161 - ko00000,ko02000 MFS_1 like family
HCBPAAJL_01494 1.11e-212 - - - S ko:K07088 - ko00000 Membrane transport protein
HCBPAAJL_01495 7.56e-267 pepA - - E - - - M42 glutamyl aminopeptidase
HCBPAAJL_01496 0.0 ykpA - - S - - - ABC transporter, ATP-binding protein
HCBPAAJL_01497 1.4e-188 - - - - - - - -
HCBPAAJL_01498 2.22e-192 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_01499 6.57e-102 - - - K - - - Transcriptional regulator, MarR family
HCBPAAJL_01500 0.0 XK27_09600 - - V ko:K06147,ko:K18891 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_01501 0.0 XK27_09605 - - V ko:K18892 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter transmembrane region
HCBPAAJL_01502 8.88e-132 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HCBPAAJL_01503 1.92e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Zeta toxin
HCBPAAJL_01504 2.39e-174 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_01505 4.3e-190 glnH - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HCBPAAJL_01506 1.43e-136 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01507 8.28e-143 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01508 3.66e-224 - - - S - - - Protein of unknown function (DUF2974)
HCBPAAJL_01509 2.75e-95 - - - - - - - -
HCBPAAJL_01510 5.02e-313 srrA1 - - G ko:K02027,ko:K17244 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HCBPAAJL_01511 5.34e-211 - - - C - - - Domain of unknown function (DUF4931)
HCBPAAJL_01512 9.2e-214 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCBPAAJL_01513 3.83e-163 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCBPAAJL_01514 0.0 kup - - P ko:K03549 - ko00000,ko02000 Transport of potassium into the cell
HCBPAAJL_01515 3.51e-223 rihC 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HCBPAAJL_01516 1.98e-175 gntR - - K - - - UbiC transcription regulator-associated domain protein
HCBPAAJL_01517 1.81e-28 - - - - - - - -
HCBPAAJL_01518 5.7e-146 - - - - - - - -
HCBPAAJL_01519 0.0 - - - V - - - ABC transporter transmembrane region
HCBPAAJL_01520 2.07e-197 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HCBPAAJL_01521 1.21e-93 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HCBPAAJL_01522 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HCBPAAJL_01523 7.73e-79 - - - S - - - Enterocin A Immunity
HCBPAAJL_01524 3.4e-178 - - - K ko:K22103 - ko00000,ko03000 DeoR C terminal sensor domain
HCBPAAJL_01525 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HCBPAAJL_01526 2.25e-206 - - - S - - - Phospholipase, patatin family
HCBPAAJL_01527 7.37e-293 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HCBPAAJL_01528 8.04e-187 - - - K ko:K07707 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HCBPAAJL_01529 5.93e-284 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HCBPAAJL_01530 1.35e-196 - - - S - - - hydrolase
HCBPAAJL_01531 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system, EIIB
HCBPAAJL_01532 1.1e-191 glvR - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HCBPAAJL_01533 2.25e-105 - - - - - - - -
HCBPAAJL_01534 5.61e-113 ptbA 2.7.1.208 - G ko:K02755,ko:K02777,ko:K20107,ko:K20108 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCBPAAJL_01535 1.51e-53 - - - - - - - -
HCBPAAJL_01536 9.09e-156 - - - C - - - nitroreductase
HCBPAAJL_01537 0.0 yhdP - - S - - - Transporter associated domain
HCBPAAJL_01538 2.11e-133 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HCBPAAJL_01539 0.0 - - - L ko:K07497 - ko00000 COG2963 Transposase and inactivated derivatives
HCBPAAJL_01540 3.27e-294 - - - E ko:K03294 - ko00000 amino acid
HCBPAAJL_01541 9.79e-168 lys - - M ko:K07273 - ko00000 Glycosyl hydrolases family 25
HCBPAAJL_01542 2.35e-269 yfmL - - L - - - DEAD DEAH box helicase
HCBPAAJL_01543 5.88e-312 chbC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_01545 2.81e-279 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCBPAAJL_01546 4.67e-116 gtcA1 - - S - - - Teichoic acid glycosylation protein
HCBPAAJL_01547 8.53e-104 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HCBPAAJL_01548 7.02e-211 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HCBPAAJL_01549 1.14e-203 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HCBPAAJL_01550 6.78e-217 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HCBPAAJL_01551 3.81e-275 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HCBPAAJL_01552 3.42e-278 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HCBPAAJL_01553 3.82e-276 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HCBPAAJL_01554 2.95e-61 - - - - - - - -
HCBPAAJL_01555 2.13e-227 ybcH - - D ko:K06889 - ko00000 Alpha beta
HCBPAAJL_01556 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCBPAAJL_01557 4.13e-187 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HCBPAAJL_01558 7.42e-112 - - - - - - - -
HCBPAAJL_01559 1.02e-93 - - - - - - - -
HCBPAAJL_01560 1.24e-201 hlyX - - S ko:K03699 - ko00000,ko02042 Transporter associated domain
HCBPAAJL_01561 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCBPAAJL_01562 3.43e-59 XK27_09445 - - S - - - Domain of unknown function (DUF1827)
HCBPAAJL_01563 0.0 clpE - - O ko:K03697 - ko00000,ko03110 Belongs to the ClpA ClpB family
HCBPAAJL_01564 9.05e-55 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HCBPAAJL_01565 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCBPAAJL_01566 1.08e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCBPAAJL_01567 2.91e-175 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCBPAAJL_01568 2.56e-209 coiA - - S ko:K06198 - ko00000 Competence protein
HCBPAAJL_01569 7.54e-149 yjbH - - Q - - - Thioredoxin
HCBPAAJL_01570 1.46e-145 - - - S - - - CYTH
HCBPAAJL_01571 1.15e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HCBPAAJL_01572 5.49e-195 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCBPAAJL_01573 1.81e-221 rluD2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HCBPAAJL_01574 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HCBPAAJL_01575 8.93e-153 - - - S - - - SNARE associated Golgi protein
HCBPAAJL_01576 1.06e-257 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HCBPAAJL_01577 0.0 pacL - - P - - - Cation transporter/ATPase, N-terminus
HCBPAAJL_01578 8.1e-87 srlB 2.7.1.198 - G ko:K02781 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system glucitol/sorbitol-specific IIA component
HCBPAAJL_01579 8.9e-270 XK27_05220 - - S - - - AI-2E family transporter
HCBPAAJL_01580 1.75e-134 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCBPAAJL_01581 1.28e-89 - - - S - - - Protein of unknown function (DUF1149)
HCBPAAJL_01582 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HCBPAAJL_01583 4.09e-291 ymfF - - S - - - Peptidase M16 inactive domain protein
HCBPAAJL_01584 2.26e-306 ymfH - - S - - - Peptidase M16
HCBPAAJL_01585 8.02e-171 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HCBPAAJL_01586 1.43e-160 ymfM - - S ko:K15539 - ko00000 Helix-turn-helix domain
HCBPAAJL_01587 1.73e-126 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCBPAAJL_01588 6.24e-247 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCBPAAJL_01589 1.29e-293 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HCBPAAJL_01590 3.37e-271 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 transferase
HCBPAAJL_01591 2.05e-153 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HCBPAAJL_01592 8.33e-314 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HCBPAAJL_01593 3.43e-171 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HCBPAAJL_01594 1.75e-123 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCBPAAJL_01595 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCBPAAJL_01596 6.43e-238 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCBPAAJL_01597 1.88e-21 - - - - - - - -
HCBPAAJL_01598 6.85e-228 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCBPAAJL_01599 4.36e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCBPAAJL_01600 1.71e-241 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HCBPAAJL_01601 9.38e-228 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCBPAAJL_01602 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCBPAAJL_01603 4.02e-284 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCBPAAJL_01604 5.82e-272 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HCBPAAJL_01605 0.0 glgA 2.4.1.21 GT5 F ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCBPAAJL_01606 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCBPAAJL_01607 0.0 malZ 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G ko:K01187,ko:K01200 ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HCBPAAJL_01608 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCBPAAJL_01609 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCBPAAJL_01610 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCBPAAJL_01611 3.8e-118 - - - S - - - Short repeat of unknown function (DUF308)
HCBPAAJL_01612 6e-212 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HCBPAAJL_01613 3.24e-250 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HCBPAAJL_01614 1.17e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HCBPAAJL_01615 2.16e-129 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCBPAAJL_01616 0.0 - - - S - - - SH3-like domain
HCBPAAJL_01617 0.0 ycaM - - E - - - amino acid
HCBPAAJL_01619 5.75e-242 cggR - - K ko:K05311 - ko00000,ko03000 Putative sugar-binding domain
HCBPAAJL_01620 4.74e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCBPAAJL_01621 9.96e-287 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HCBPAAJL_01622 2.71e-183 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCBPAAJL_01623 1.07e-125 - - - - - - - -
HCBPAAJL_01624 1.02e-202 ycsE - - S - - - Sucrose-6F-phosphate phosphohydrolase
HCBPAAJL_01625 1.15e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCBPAAJL_01626 3.84e-233 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HCBPAAJL_01627 4.82e-113 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HCBPAAJL_01628 5.26e-128 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HCBPAAJL_01629 7.27e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HCBPAAJL_01630 2.94e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCBPAAJL_01631 1.04e-180 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01632 2.65e-179 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01633 9.5e-264 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HCBPAAJL_01634 1.06e-194 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCBPAAJL_01635 3.38e-221 ybbR - - S - - - YbbR-like protein
HCBPAAJL_01636 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCBPAAJL_01637 4.85e-191 - - - S - - - hydrolase
HCBPAAJL_01638 1.45e-187 - - - S - - - Sucrose-6F-phosphate phosphohydrolase
HCBPAAJL_01639 7.3e-156 - - - - - - - -
HCBPAAJL_01640 2.73e-111 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCBPAAJL_01641 1.37e-269 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HCBPAAJL_01642 4.66e-196 bglG5 - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HCBPAAJL_01643 0.0 pts33BCA - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_01644 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_01645 6.14e-232 ybcH - - D ko:K06889 - ko00000 Alpha beta
HCBPAAJL_01646 0.0 - - - E - - - Amino acid permease
HCBPAAJL_01648 1.96e-37 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCBPAAJL_01649 2.34e-119 - - - S - - - VanZ like family
HCBPAAJL_01650 1.97e-171 yebC - - K - - - Transcriptional regulatory protein
HCBPAAJL_01651 1.38e-228 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HCBPAAJL_01652 5.57e-224 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HCBPAAJL_01653 1.55e-65 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HCBPAAJL_01654 9e-94 - - - - ko:K02246 - ko00000,ko00002,ko02044 -
HCBPAAJL_01655 1.33e-25 - - - - - - - -
HCBPAAJL_01656 2.61e-120 - - - U ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HCBPAAJL_01657 4.19e-239 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HCBPAAJL_01658 1.35e-284 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCBPAAJL_01660 1.05e-170 - - - M - - - Protein of unknown function (DUF3737)
HCBPAAJL_01661 3.52e-224 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HCBPAAJL_01662 4.53e-41 - 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HCBPAAJL_01663 1.86e-245 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HCBPAAJL_01664 1.68e-81 - - - S - - - SdpI/YhfL protein family
HCBPAAJL_01665 1.97e-170 - - - K - - - Transcriptional regulatory protein, C terminal
HCBPAAJL_01666 0.0 yclK - - T - - - Histidine kinase
HCBPAAJL_01667 4.37e-81 XK27_00915 - - C - - - Luciferase-like monooxygenase
HCBPAAJL_01668 1.53e-159 XK27_00915 - - C - - - Luciferase-like monooxygenase
HCBPAAJL_01669 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCBPAAJL_01670 1.93e-139 vanZ - - V - - - VanZ like family
HCBPAAJL_01671 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HCBPAAJL_01672 5.4e-316 - - - EGP - - - Major Facilitator
HCBPAAJL_01673 7.36e-251 ampC - - V - - - Beta-lactamase
HCBPAAJL_01676 2.17e-85 - - - - - - - -
HCBPAAJL_01677 0.0 - - - S ko:K06919 - ko00000 DNA primase
HCBPAAJL_01678 1.18e-47 - - - - - - - -
HCBPAAJL_01679 6.8e-46 - - - - - - - -
HCBPAAJL_01680 3.84e-90 - - - - - - - -
HCBPAAJL_01681 2.58e-49 - - - - - - - -
HCBPAAJL_01683 3.5e-75 - - - K - - - Transcriptional
HCBPAAJL_01684 1.58e-266 - - - L - - - Belongs to the 'phage' integrase family
HCBPAAJL_01685 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Domain of unknown function (DUF1727)
HCBPAAJL_01686 4.64e-146 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HCBPAAJL_01687 1.01e-235 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCBPAAJL_01688 2.52e-202 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCBPAAJL_01689 4.93e-243 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCBPAAJL_01690 1.84e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCBPAAJL_01691 4.13e-166 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HCBPAAJL_01692 4.36e-39 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBPAAJL_01693 4.97e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCBPAAJL_01694 6.82e-122 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCBPAAJL_01695 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCBPAAJL_01696 1.22e-220 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCBPAAJL_01697 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCBPAAJL_01698 7.03e-93 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HCBPAAJL_01699 4.22e-41 - - - S - - - Protein of unknown function (DUF1146)
HCBPAAJL_01700 2.04e-228 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HCBPAAJL_01701 7.58e-67 ytjA - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HCBPAAJL_01702 1.26e-46 - - - S - - - Protein of unknown function (DUF2969)
HCBPAAJL_01703 1.18e-275 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HCBPAAJL_01704 6.39e-102 uspA - - T - - - universal stress protein
HCBPAAJL_01705 1.41e-49 - - - - - - - -
HCBPAAJL_01706 1.18e-310 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HCBPAAJL_01707 9.44e-109 - - - S - - - Protein of unknown function (DUF1694)
HCBPAAJL_01708 1.07e-142 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCBPAAJL_01709 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCBPAAJL_01710 1.29e-278 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HCBPAAJL_01711 4.62e-293 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCBPAAJL_01712 1.56e-165 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HCBPAAJL_01713 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCBPAAJL_01714 2.55e-306 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HCBPAAJL_01715 1.83e-163 - - - S - - - Haloacid dehalogenase-like hydrolase
HCBPAAJL_01716 2.34e-148 radC - - L ko:K03630 - ko00000 DNA repair protein
HCBPAAJL_01717 2.03e-226 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HCBPAAJL_01718 1.82e-192 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HCBPAAJL_01719 6.61e-123 mreD - - - ko:K03571 - ko00000,ko03036 -
HCBPAAJL_01720 1.45e-14 - - - S - - - Protein of unknown function (DUF4044)
HCBPAAJL_01721 4.84e-71 - - - S - - - Protein of unknown function (DUF3397)
HCBPAAJL_01722 3.95e-93 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HCBPAAJL_01723 5.41e-226 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCBPAAJL_01724 1.32e-71 ftsL - - D - - - Cell division protein FtsL
HCBPAAJL_01725 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HCBPAAJL_01726 8e-227 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCBPAAJL_01727 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCBPAAJL_01728 4.93e-267 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCBPAAJL_01729 1.71e-182 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCBPAAJL_01730 1.02e-312 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCBPAAJL_01731 5.9e-313 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCBPAAJL_01732 4.09e-96 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCBPAAJL_01733 1.36e-39 yggT - - S ko:K02221 - ko00000,ko02044 YGGT family
HCBPAAJL_01734 4.87e-193 ylmH - - S - - - S4 domain protein
HCBPAAJL_01735 1.18e-141 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HCBPAAJL_01736 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCBPAAJL_01737 8.09e-44 cspA - - K ko:K03704 - ko00000,ko03000 'Cold-shock' DNA-binding domain
HCBPAAJL_01738 6.29e-135 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HCBPAAJL_01739 4.49e-42 - - - - - - - -
HCBPAAJL_01740 1.02e-163 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCBPAAJL_01741 1.47e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HCBPAAJL_01742 1.62e-280 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCBPAAJL_01743 1.58e-161 pgm - - G - - - Phosphoglycerate mutase family
HCBPAAJL_01744 2.93e-150 - - - S - - - repeat protein
HCBPAAJL_01745 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCBPAAJL_01746 0.0 - - - L - - - Nuclease-related domain
HCBPAAJL_01747 1.29e-233 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HCBPAAJL_01748 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBPAAJL_01749 3.13e-46 ykzG - - S - - - Belongs to the UPF0356 family
HCBPAAJL_01750 2.52e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCBPAAJL_01751 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HCBPAAJL_01752 2.75e-268 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HCBPAAJL_01753 4.73e-69 ylbG - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HCBPAAJL_01754 5.62e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HCBPAAJL_01755 7.07e-107 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCBPAAJL_01756 1.37e-246 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HCBPAAJL_01757 2.19e-131 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HCBPAAJL_01758 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HCBPAAJL_01759 3.38e-227 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HCBPAAJL_01760 3.78e-48 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HCBPAAJL_01761 4.08e-55 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCBPAAJL_01762 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCBPAAJL_01763 1.45e-195 - - - - - - - -
HCBPAAJL_01764 8.19e-287 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCBPAAJL_01765 3.02e-294 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCBPAAJL_01766 8.42e-299 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCBPAAJL_01767 1.17e-138 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HCBPAAJL_01768 7.3e-245 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCBPAAJL_01769 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HCBPAAJL_01770 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCBPAAJL_01771 1.39e-106 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCBPAAJL_01772 5.48e-283 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCBPAAJL_01773 1.14e-225 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCBPAAJL_01774 1.23e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCBPAAJL_01775 2.42e-281 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HCBPAAJL_01776 4.28e-253 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCBPAAJL_01777 8.12e-262 pbpX1 - - V - - - Beta-lactamase
HCBPAAJL_01778 0.0 - - - I - - - Protein of unknown function (DUF2974)
HCBPAAJL_01779 1.18e-55 - - - C - - - FMN_bind
HCBPAAJL_01780 1.01e-104 - - - - - - - -
HCBPAAJL_01781 0.0 - - - - - - - -
HCBPAAJL_01782 4.65e-228 iunH 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 inosine-uridine preferring nucleoside hydrolase
HCBPAAJL_01783 8.04e-188 - - - - - - - -
HCBPAAJL_01787 1.93e-25 alkD - - L - - - DNA alkylation repair enzyme
HCBPAAJL_01788 4.23e-93 alkD - - L - - - DNA alkylation repair enzyme
HCBPAAJL_01789 3.08e-52 - - - S - - - Transglycosylase associated protein
HCBPAAJL_01790 6.28e-10 - - - S - - - CsbD-like
HCBPAAJL_01791 0.0 pbg4 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_01792 1.62e-166 - - - K ko:K03492 - ko00000,ko03000 UTRA domain
HCBPAAJL_01793 4.98e-74 pts20B 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose/Cellobiose specific IIB subunit
HCBPAAJL_01794 4.75e-80 celC 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system, Lactose Cellobiose specific IIA subunit
HCBPAAJL_01795 4.68e-104 - - - - - - - -
HCBPAAJL_01796 1.68e-179 celD - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_01797 2.84e-94 - - - S - - - Domain of unknown function (DUF3284)
HCBPAAJL_01798 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_01799 1.45e-172 - - - K ko:K03492 - ko00000,ko03000 UTRA
HCBPAAJL_01800 1.91e-55 - - - - - - - -
HCBPAAJL_01801 0.0 pts23C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_01802 0.0 pbg6 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HCBPAAJL_01803 3.69e-207 ypbG 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HCBPAAJL_01804 1.01e-111 yfhC - - C - - - Nitroreductase family
HCBPAAJL_01805 4.93e-141 - - - S - - - Domain of unknown function (DUF4767)
HCBPAAJL_01806 2.12e-312 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCBPAAJL_01807 1.19e-194 - - - S - - - Uncharacterised protein, DegV family COG1307
HCBPAAJL_01808 2.64e-128 - - - I - - - PAP2 superfamily
HCBPAAJL_01809 1.47e-244 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCBPAAJL_01811 2.59e-229 int3 - - L - - - Belongs to the 'phage' integrase family
HCBPAAJL_01812 1.09e-34 - - - - - - - -
HCBPAAJL_01813 1.98e-129 - - - - - - - -
HCBPAAJL_01814 0.000281 - - - - - - - -
HCBPAAJL_01815 9.27e-75 - - - K - - - Cro/C1-type HTH DNA-binding domain
HCBPAAJL_01816 2.16e-39 - - - K - - - Helix-turn-helix XRE-family like proteins
HCBPAAJL_01817 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HCBPAAJL_01818 1.21e-244 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCBPAAJL_01819 1.53e-122 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCBPAAJL_01820 0.0 aha1 - - P ko:K12952 - ko00000,ko01000 E1-E2 ATPase
HCBPAAJL_01821 1.03e-203 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HCBPAAJL_01822 2.07e-240 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCBPAAJL_01823 4.45e-127 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HCBPAAJL_01824 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCBPAAJL_01825 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HCBPAAJL_01826 0.0 - - - M - - - domain protein
HCBPAAJL_01827 5.14e-216 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HCBPAAJL_01828 0.0 pepC4 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HCBPAAJL_01829 0.0 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HCBPAAJL_01830 7.54e-200 - - - I - - - Alpha/beta hydrolase family
HCBPAAJL_01831 7.35e-249 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCBPAAJL_01832 2.76e-60 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HCBPAAJL_01833 6.24e-215 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HCBPAAJL_01834 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HCBPAAJL_01835 1.24e-93 ytwI - - S - - - Protein of unknown function (DUF441)
HCBPAAJL_01836 6.03e-19 - - - - - - - -
HCBPAAJL_01837 1.14e-192 cbiQ - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 cobalt transport
HCBPAAJL_01838 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HCBPAAJL_01839 4.42e-124 - - - S ko:K16924 - ko00000,ko00002,ko02000 UPF0397 protein
HCBPAAJL_01840 2.09e-83 - - - S - - - Domain of unknown function DUF1828
HCBPAAJL_01841 5.21e-71 - - - - - - - -
HCBPAAJL_01842 1.56e-228 citR - - K - - - Putative sugar-binding domain
HCBPAAJL_01843 3.82e-312 - - - S - - - Putative threonine/serine exporter
HCBPAAJL_01844 7.54e-115 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCBPAAJL_01845 1.32e-221 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HCBPAAJL_01846 1.17e-65 - - - - - - - -
HCBPAAJL_01847 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCBPAAJL_01848 2.56e-99 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCBPAAJL_01849 1.74e-311 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HCBPAAJL_01850 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCBPAAJL_01851 9.94e-287 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HCBPAAJL_01852 1.03e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCBPAAJL_01853 2.72e-197 - - - S - - - reductase
HCBPAAJL_01854 3.29e-193 yxeH - - S - - - hydrolase
HCBPAAJL_01855 2.31e-230 gyaR 1.1.1.26, 1.1.1.399, 1.1.1.95 - CH ko:K00015,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCBPAAJL_01856 5.04e-298 yhdG - - E ko:K03294 - ko00000 Amino Acid
HCBPAAJL_01857 4.52e-140 yngC - - S - - - SNARE associated Golgi protein
HCBPAAJL_01858 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCBPAAJL_01859 3.01e-310 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCBPAAJL_01860 0.0 oatA - - I - - - Acyltransferase
HCBPAAJL_01861 6.35e-228 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCBPAAJL_01862 1.5e-186 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HCBPAAJL_01863 2.25e-45 - - - S - - - Lipopolysaccharide assembly protein A domain
HCBPAAJL_01864 3.62e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HCBPAAJL_01865 0.0 yfkN 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HCBPAAJL_01866 3.9e-33 - - - S - - - Protein of unknown function (DUF2929)
HCBPAAJL_01867 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HCBPAAJL_01868 7.76e-233 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCBPAAJL_01869 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HCBPAAJL_01870 1e-216 yitL - - S ko:K00243 - ko00000 S1 domain
HCBPAAJL_01871 2.19e-218 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HCBPAAJL_01872 6.56e-81 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBPAAJL_01873 1.81e-169 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCBPAAJL_01874 5.75e-135 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCBPAAJL_01875 3.66e-165 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HCBPAAJL_01876 6.79e-152 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCBPAAJL_01877 7.33e-71 - - - M - - - Lysin motif
HCBPAAJL_01878 1.28e-147 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HCBPAAJL_01879 4.07e-270 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HCBPAAJL_01880 3.15e-313 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HCBPAAJL_01881 1.17e-56 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCBPAAJL_01882 2.22e-296 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HCBPAAJL_01883 1.3e-207 XK27_10395 - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCBPAAJL_01884 8.15e-284 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCBPAAJL_01885 7.33e-143 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HCBPAAJL_01886 6.34e-193 degV3 - - S - - - Uncharacterised protein, DegV family COG1307
HCBPAAJL_01887 1.64e-47 yozE - - S - - - Belongs to the UPF0346 family
HCBPAAJL_01888 0.0 nhaP4 - - P ko:K03316 - ko00000 Sodium proton antiporter
HCBPAAJL_01889 8.81e-205 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCBPAAJL_01890 8.96e-172 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCBPAAJL_01891 1.07e-201 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HCBPAAJL_01892 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCBPAAJL_01893 2.09e-315 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCBPAAJL_01894 2.27e-216 xerC - - D ko:K03733,ko:K04763 - ko00000,ko03036 Phage integrase, N-terminal SAM-like domain
HCBPAAJL_01895 3.29e-116 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCBPAAJL_01896 4.61e-308 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCBPAAJL_01897 7.16e-232 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HCBPAAJL_01898 1.72e-85 - - - - - - - -
HCBPAAJL_01899 4.82e-296 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCBPAAJL_01900 1.25e-204 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HCBPAAJL_01901 2.82e-194 - - - L - - - Phage integrase, N-terminal SAM-like domain
HCBPAAJL_01902 7.42e-89 crcB1 - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBPAAJL_01903 9.18e-83 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCBPAAJL_01904 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HCBPAAJL_01905 0.0 - - - E - - - Amino acid permease
HCBPAAJL_01906 0.0 speA 4.1.1.17, 4.1.1.18, 4.1.1.19 - E ko:K01581,ko:K01582,ko:K01585 ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Orn/Lys/Arg decarboxylase, C-terminal domain
HCBPAAJL_01907 1.13e-312 ynbB - - P - - - aluminum resistance
HCBPAAJL_01908 6.35e-154 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HCBPAAJL_01909 7.3e-304 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HCBPAAJL_01910 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HCBPAAJL_01911 1.47e-105 - - - C - - - Flavodoxin
HCBPAAJL_01912 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HCBPAAJL_01913 4.33e-234 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine S-methyltransferase
HCBPAAJL_01914 8.43e-148 - - - I - - - Acid phosphatase homologues
HCBPAAJL_01915 5.22e-89 yvbK - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCBPAAJL_01916 1.71e-265 - - - V - - - Beta-lactamase
HCBPAAJL_01917 2.42e-201 pdxK 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Phosphomethylpyrimidine kinase
HCBPAAJL_01918 2.46e-121 - - - S - - - ECF-type riboflavin transporter, S component
HCBPAAJL_01919 1.84e-281 - - - S - - - Putative peptidoglycan binding domain
HCBPAAJL_01920 5.05e-313 - - - - - - - -
HCBPAAJL_01921 0.0 treB - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HCBPAAJL_01922 2.78e-166 treR - - K ko:K03486 - ko00000,ko03000 UTRA
HCBPAAJL_01923 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HCBPAAJL_01924 5.68e-165 - - - M - - - Glycosyl transferases group 1

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)