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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PIOLMLDC_00018	2.12e-81	-	-	-	-	-	-	-	-
PIOLMLDC_00030	4.69e-282	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
PIOLMLDC_00031	1.68e-252	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PIOLMLDC_00032	1.28e-231	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PIOLMLDC_00033	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIOLMLDC_00053	1.24e-312	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PIOLMLDC_00054	4.12e-254	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00055	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PIOLMLDC_00056	3.15e-219	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PIOLMLDC_00057	2.91e-94	-	-	-	-	-	-	-	-
PIOLMLDC_00058	8.16e-111	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
PIOLMLDC_00059	2.49e-56	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PIOLMLDC_00060	0.0	-	-	-	S	-	-	-	TerB-C domain
PIOLMLDC_00061	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
PIOLMLDC_00062	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
PIOLMLDC_00063	7.28e-243	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PIOLMLDC_00064	5.8e-49	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
PIOLMLDC_00065	3.24e-110	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
PIOLMLDC_00066	3.97e-311	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
PIOLMLDC_00067	2.09e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
PIOLMLDC_00069	2.93e-114	-	-	-	K	-	-	-	acetyltransferase
PIOLMLDC_00070	2.95e-77	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PIOLMLDC_00071	2.22e-171	-	-	-	S	-	-	-	Putative ABC-transporter type IV
PIOLMLDC_00072	1.07e-159	-	-	-	M	-	-	-	LysM domain protein
PIOLMLDC_00073	2.87e-183	-	-	-	M	-	-	-	LysM domain protein
PIOLMLDC_00075	2.51e-49	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
PIOLMLDC_00076	3.46e-211	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PIOLMLDC_00079	1.19e-69	XK27_05625	-	-	P	-	-	-	Rhodanese Homology Domain
PIOLMLDC_00080	1.24e-242	-	-	-	-	-	-	-	-
PIOLMLDC_00081	2.57e-158	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PIOLMLDC_00082	1.44e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
PIOLMLDC_00083	3e-168	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PIOLMLDC_00084	9.49e-262	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIOLMLDC_00085	0.0	-	-	-	S	-	-	-	Glycosyltransferase like family 2
PIOLMLDC_00086	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PIOLMLDC_00087	9.12e-199	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PIOLMLDC_00088	1.07e-300	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
PIOLMLDC_00089	7.32e-158	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
PIOLMLDC_00090	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIOLMLDC_00091	2.62e-285	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PIOLMLDC_00092	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIOLMLDC_00093	1.15e-170	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PIOLMLDC_00094	5.29e-109	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PIOLMLDC_00096	4.82e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PIOLMLDC_00097	3.3e-144	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PIOLMLDC_00098	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PIOLMLDC_00099	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PIOLMLDC_00100	1.12e-264	camS	-	-	S	-	-	-	sex pheromone
PIOLMLDC_00101	2.23e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIOLMLDC_00102	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PIOLMLDC_00103	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PIOLMLDC_00104	5.13e-213	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PIOLMLDC_00106	1.39e-190	-	-	-	S	-	-	-	hydrolase
PIOLMLDC_00107	3.2e-09	-	-	-	UW	-	-	-	Tetratricopeptide repeat
PIOLMLDC_00108	0.0	-	-	-	UW	-	-	-	Tetratricopeptide repeat
PIOLMLDC_00109	2.49e-105	-	-	-	UW	-	-	-	Tetratricopeptide repeat
PIOLMLDC_00110	0.0	-	-	-	M	-	-	-	family 8
PIOLMLDC_00111	0.0	-	-	-	M	-	-	-	family 8
PIOLMLDC_00112	3.82e-152	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PIOLMLDC_00113	1.8e-184	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PIOLMLDC_00114	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_00115	1.17e-92	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PIOLMLDC_00116	3.34e-118	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
PIOLMLDC_00117	6.08e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
PIOLMLDC_00118	3.67e-163	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_00119	5.21e-155	-	-	-	S	ko:K01992,ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
PIOLMLDC_00120	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIOLMLDC_00121	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
PIOLMLDC_00122	1.58e-45	-	-	-	C	-	-	-	Heavy-metal-associated domain
PIOLMLDC_00123	1.49e-120	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PIOLMLDC_00124	5.63e-145	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
PIOLMLDC_00125	6.19e-84	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PIOLMLDC_00126	3.77e-247	flp	-	-	V	-	-	-	Beta-lactamase
PIOLMLDC_00127	1.7e-138	-	2.7.1.95	-	F	ko:K00897	-	ko00000,ko01000,ko01504	Belongs to the aminoglycoside phosphotransferase family
PIOLMLDC_00128	1.17e-15	-	-	-	F	-	-	-	adenylate kinase activity
PIOLMLDC_00130	2.95e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PIOLMLDC_00131	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PIOLMLDC_00132	1.29e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
PIOLMLDC_00133	4.66e-278	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
PIOLMLDC_00134	0.0	yhaN	-	-	L	-	-	-	AAA domain
PIOLMLDC_00135	1.25e-236	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIOLMLDC_00136	3.55e-202	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PIOLMLDC_00137	1.2e-47	-	-	-	S	-	-	-	YtxH-like protein
PIOLMLDC_00138	2.56e-85	-	-	-	-	-	-	-	-
PIOLMLDC_00139	5.83e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
PIOLMLDC_00140	1.38e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_00141	1.36e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PIOLMLDC_00142	2.83e-159	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PIOLMLDC_00143	2.82e-83	-	-	-	-	-	-	-	-
PIOLMLDC_00144	1.11e-70	ytpP	-	-	CO	-	-	-	Thioredoxin
PIOLMLDC_00145	2.42e-154	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIOLMLDC_00146	9.29e-110	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
PIOLMLDC_00147	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PIOLMLDC_00148	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PIOLMLDC_00149	1.93e-204	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PIOLMLDC_00150	2.08e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PIOLMLDC_00151	8.41e-107	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PIOLMLDC_00152	1.87e-306	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
PIOLMLDC_00153	1.86e-193	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PIOLMLDC_00154	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PIOLMLDC_00155	5.61e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIOLMLDC_00156	1.43e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PIOLMLDC_00157	2.07e-300	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIOLMLDC_00158	1.29e-112	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PIOLMLDC_00159	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PIOLMLDC_00160	3.54e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PIOLMLDC_00161	9.82e-134	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PIOLMLDC_00162	8.42e-263	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00163	2.27e-36	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PIOLMLDC_00164	5.71e-116	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PIOLMLDC_00165	3.91e-269	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PIOLMLDC_00166	9.16e-151	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PIOLMLDC_00167	7.3e-143	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PIOLMLDC_00168	4.36e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PIOLMLDC_00169	5.65e-277	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PIOLMLDC_00170	6.07e-120	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PIOLMLDC_00171	1.89e-169	csrR	-	-	K	-	-	-	response regulator
PIOLMLDC_00172	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIOLMLDC_00173	2.72e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIOLMLDC_00174	8.53e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PIOLMLDC_00175	3.14e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIOLMLDC_00176	1.19e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PIOLMLDC_00177	3.68e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PIOLMLDC_00178	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PIOLMLDC_00179	1.84e-260	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PIOLMLDC_00180	5.34e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIOLMLDC_00181	0.0	-	-	-	S	-	-	-	membrane
PIOLMLDC_00182	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PIOLMLDC_00183	3.09e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PIOLMLDC_00184	5.61e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PIOLMLDC_00185	2.67e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
PIOLMLDC_00186	3.31e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PIOLMLDC_00187	1.21e-75	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PIOLMLDC_00188	1.18e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PIOLMLDC_00189	1.35e-210	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PIOLMLDC_00190	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PIOLMLDC_00191	3.16e-260	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIOLMLDC_00192	1.23e-188	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PIOLMLDC_00194	1.1e-229	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PIOLMLDC_00195	1.44e-276	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PIOLMLDC_00196	2.83e-281	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PIOLMLDC_00197	1.33e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PIOLMLDC_00198	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PIOLMLDC_00199	9e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PIOLMLDC_00200	1.13e-145	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PIOLMLDC_00201	7.91e-115	-	-	-	-	-	-	-	-
PIOLMLDC_00202	4.87e-101	-	-	-	-	-	-	-	-
PIOLMLDC_00203	1.57e-200	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PIOLMLDC_00204	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PIOLMLDC_00205	2.17e-59	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PIOLMLDC_00206	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PIOLMLDC_00207	1.02e-34	-	-	-	-	-	-	-	-
PIOLMLDC_00208	7.45e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PIOLMLDC_00209	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PIOLMLDC_00210	2.87e-88	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PIOLMLDC_00211	1.91e-152	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PIOLMLDC_00212	9.65e-193	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PIOLMLDC_00213	2.99e-137	yjbH	-	-	Q	-	-	-	Thioredoxin
PIOLMLDC_00214	9.83e-141	-	-	-	S	-	-	-	CYTH
PIOLMLDC_00215	1.7e-146	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PIOLMLDC_00216	3.58e-197	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PIOLMLDC_00217	5.15e-216	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIOLMLDC_00218	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PIOLMLDC_00219	1.35e-303	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PIOLMLDC_00220	2.38e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PIOLMLDC_00221	1.64e-86	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PIOLMLDC_00222	1.16e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PIOLMLDC_00223	5.41e-134	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PIOLMLDC_00224	2.29e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
PIOLMLDC_00225	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PIOLMLDC_00226	1.43e-291	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PIOLMLDC_00227	6.61e-296	ymfH	-	-	S	-	-	-	Peptidase M16
PIOLMLDC_00228	4.99e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PIOLMLDC_00229	1.2e-170	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PIOLMLDC_00230	3.1e-125	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PIOLMLDC_00231	6.02e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PIOLMLDC_00232	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PIOLMLDC_00233	1.91e-261	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
PIOLMLDC_00234	3.53e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PIOLMLDC_00235	5.24e-278	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PIOLMLDC_00236	2.06e-159	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PIOLMLDC_00237	3.97e-125	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PIOLMLDC_00238	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIOLMLDC_00239	3.42e-233	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PIOLMLDC_00240	6.45e-41	-	-	-	-	-	-	-	-
PIOLMLDC_00241	5.58e-221	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PIOLMLDC_00242	4.18e-200	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PIOLMLDC_00243	1.57e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PIOLMLDC_00244	8.96e-223	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PIOLMLDC_00245	3.94e-198	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PIOLMLDC_00246	1.08e-255	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIOLMLDC_00247	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PIOLMLDC_00248	4.46e-211	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PIOLMLDC_00249	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PIOLMLDC_00250	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PIOLMLDC_00251	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PIOLMLDC_00252	2.04e-117	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PIOLMLDC_00253	1.58e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PIOLMLDC_00254	1.54e-247	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PIOLMLDC_00255	2.02e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PIOLMLDC_00256	3.74e-130	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PIOLMLDC_00257	0.0	ycaM	-	-	E	-	-	-	amino acid
PIOLMLDC_00259	3.72e-238	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PIOLMLDC_00260	4.74e-243	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PIOLMLDC_00261	7.02e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PIOLMLDC_00262	5.9e-182	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PIOLMLDC_00263	1.18e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIOLMLDC_00264	7.52e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PIOLMLDC_00265	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PIOLMLDC_00266	2.95e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PIOLMLDC_00267	1.88e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
PIOLMLDC_00268	4.65e-112	-	-	-	-	-	-	-	-
PIOLMLDC_00269	3.45e-121	-	-	-	-	-	-	-	-
PIOLMLDC_00270	2.92e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIOLMLDC_00271	1.02e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PIOLMLDC_00272	4.47e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PIOLMLDC_00273	5.02e-110	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PIOLMLDC_00274	2.23e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PIOLMLDC_00275	4.55e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PIOLMLDC_00276	1.1e-258	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PIOLMLDC_00277	2.51e-172	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_00278	2.65e-176	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_00279	4.21e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_00280	6.38e-197	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PIOLMLDC_00281	7.35e-223	ybbR	-	-	S	-	-	-	YbbR-like protein
PIOLMLDC_00282	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PIOLMLDC_00283	2.8e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PIOLMLDC_00284	3.02e-88	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIOLMLDC_00285	8.65e-81	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PIOLMLDC_00286	1.42e-255	-	-	-	S	-	-	-	Putative adhesin
PIOLMLDC_00287	2.13e-142	-	-	-	-	-	-	-	-
PIOLMLDC_00288	8.42e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PIOLMLDC_00289	8.84e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIOLMLDC_00290	4.49e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PIOLMLDC_00291	3.07e-124	-	-	-	S	-	-	-	VanZ like family
PIOLMLDC_00292	6.1e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PIOLMLDC_00293	4.12e-254	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00294	2.89e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PIOLMLDC_00295	8.17e-221	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PIOLMLDC_00296	8.87e-53	comGC	-	-	U	ko:K02245,ko:K02456	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02044	Required for transformation and DNA binding
PIOLMLDC_00297	4.63e-76	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
PIOLMLDC_00299	2.27e-104	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
PIOLMLDC_00300	8.11e-237	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PIOLMLDC_00301	1.37e-288	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIOLMLDC_00303	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	Levansucrase/Invertase
PIOLMLDC_00304	4.17e-121	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PIOLMLDC_00305	3.96e-274	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PIOLMLDC_00306	6.42e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PIOLMLDC_00307	4.63e-88	-	-	-	S	-	-	-	SdpI/YhfL protein family
PIOLMLDC_00308	3.67e-164	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PIOLMLDC_00309	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PIOLMLDC_00310	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PIOLMLDC_00311	8.79e-136	vanZ	-	-	V	-	-	-	VanZ like family
PIOLMLDC_00312	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PIOLMLDC_00313	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PIOLMLDC_00314	3.21e-89	-	-	-	-	-	-	-	-
PIOLMLDC_00317	8.25e-249	ampC	-	-	V	-	-	-	Beta-lactamase
PIOLMLDC_00318	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Mur ligase, middle domain
PIOLMLDC_00319	8.2e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PIOLMLDC_00320	1.8e-250	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PIOLMLDC_00321	8.8e-203	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PIOLMLDC_00322	3.46e-241	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PIOLMLDC_00323	2.61e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PIOLMLDC_00324	7.4e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PIOLMLDC_00325	1.75e-35	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIOLMLDC_00326	5.6e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PIOLMLDC_00327	1.13e-120	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PIOLMLDC_00328	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PIOLMLDC_00329	1.65e-217	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PIOLMLDC_00330	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PIOLMLDC_00331	2.1e-94	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PIOLMLDC_00332	3.07e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PIOLMLDC_00333	3.53e-229	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PIOLMLDC_00334	1.65e-18	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
PIOLMLDC_00335	1.12e-68	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PIOLMLDC_00336	1.79e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PIOLMLDC_00337	2.52e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PIOLMLDC_00338	3.52e-106	uspA	-	-	T	-	-	-	universal stress protein
PIOLMLDC_00339	9.34e-08	-	-	-	-	-	-	-	-
PIOLMLDC_00340	1.31e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PIOLMLDC_00341	2.82e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PIOLMLDC_00342	7.54e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PIOLMLDC_00344	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PIOLMLDC_00345	6.1e-276	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PIOLMLDC_00346	2.1e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PIOLMLDC_00347	1.86e-151	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PIOLMLDC_00348	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PIOLMLDC_00349	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PIOLMLDC_00350	3.04e-297	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PIOLMLDC_00351	1.29e-159	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PIOLMLDC_00352	9.17e-144	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PIOLMLDC_00353	3.11e-225	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PIOLMLDC_00354	1.17e-188	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PIOLMLDC_00355	3.99e-123	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
PIOLMLDC_00356	2.36e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PIOLMLDC_00357	2.2e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
PIOLMLDC_00358	1.89e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PIOLMLDC_00359	1.02e-229	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PIOLMLDC_00360	3.95e-73	ftsL	-	-	D	-	-	-	Cell division protein FtsL
PIOLMLDC_00361	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PIOLMLDC_00362	9e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PIOLMLDC_00363	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PIOLMLDC_00364	1.3e-263	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PIOLMLDC_00365	4.49e-197	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PIOLMLDC_00366	8.61e-308	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PIOLMLDC_00367	3.29e-313	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PIOLMLDC_00368	9.26e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PIOLMLDC_00369	1.36e-47	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
PIOLMLDC_00370	5.66e-187	ylmH	-	-	S	-	-	-	S4 domain protein
PIOLMLDC_00371	1.07e-153	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
PIOLMLDC_00372	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PIOLMLDC_00373	1.37e-45	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PIOLMLDC_00374	1.81e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PIOLMLDC_00375	2.58e-51	-	-	-	-	-	-	-	-
PIOLMLDC_00376	2.91e-164	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PIOLMLDC_00377	1.38e-272	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PIOLMLDC_00378	6.06e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PIOLMLDC_00379	2.58e-277	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PIOLMLDC_00380	8.76e-159	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
PIOLMLDC_00381	1.63e-147	-	-	-	S	-	-	-	repeat protein
PIOLMLDC_00382	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PIOLMLDC_00383	5.63e-226	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PIOLMLDC_00384	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIOLMLDC_00385	3.08e-47	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PIOLMLDC_00386	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PIOLMLDC_00387	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PIOLMLDC_00388	9.19e-267	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PIOLMLDC_00389	3.85e-64	ylbG	-	-	S	-	-	-	UPF0298 protein
PIOLMLDC_00390	8.3e-123	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PIOLMLDC_00391	3.34e-112	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PIOLMLDC_00392	9.82e-235	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PIOLMLDC_00393	7.81e-141	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PIOLMLDC_00394	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PIOLMLDC_00395	3.38e-227	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PIOLMLDC_00396	1.27e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PIOLMLDC_00397	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PIOLMLDC_00398	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PIOLMLDC_00399	1.35e-204	-	-	-	-	-	-	-	-
PIOLMLDC_00400	2.45e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PIOLMLDC_00401	2.09e-277	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PIOLMLDC_00402	2.76e-268	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIOLMLDC_00403	1.44e-295	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PIOLMLDC_00404	5.34e-134	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PIOLMLDC_00405	6.6e-115	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PIOLMLDC_00406	1.1e-108	-	-	-	-	-	-	-	-
PIOLMLDC_00408	4.86e-150	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PIOLMLDC_00409	5.4e-112	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
PIOLMLDC_00410	2.43e-283	-	-	-	-	-	-	-	-
PIOLMLDC_00411	1.39e-156	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	DSBA-like thioredoxin domain
PIOLMLDC_00412	1.26e-208	-	-	-	-	-	-	-	-
PIOLMLDC_00413	9.63e-100	-	-	-	K	-	-	-	DNA-templated transcription, initiation
PIOLMLDC_00414	4.99e-211	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIOLMLDC_00415	4.78e-174	epsB	-	-	M	-	-	-	biosynthesis protein
PIOLMLDC_00416	6.86e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PIOLMLDC_00417	2.68e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PIOLMLDC_00418	1.37e-101	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
PIOLMLDC_00419	2.21e-51	-	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
PIOLMLDC_00420	6.92e-51	-	-	-	H	-	-	-	Core-2/I-Branching enzyme
PIOLMLDC_00421	1.98e-65	wbbK	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PIOLMLDC_00422	5.89e-33	rfbF	-	GT2	V	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase, family 2
PIOLMLDC_00423	1.82e-119	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIOLMLDC_00424	1.4e-47	-	-	-	S	-	-	-	Glycosyl transferase family 2
PIOLMLDC_00426	1.62e-48	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PIOLMLDC_00427	2.66e-272	ugd	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	UDP binding domain
PIOLMLDC_00428	5.89e-214	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
PIOLMLDC_00429	7.8e-282	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
PIOLMLDC_00430	7.8e-266	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PIOLMLDC_00431	5.97e-208	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PIOLMLDC_00432	7.02e-152	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PIOLMLDC_00433	7.27e-242	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PIOLMLDC_00434	2.65e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_00435	0.0	-	-	-	L	ko:K07459	-	ko00000	AAA ATPase domain
PIOLMLDC_00436	7.83e-317	-	-	-	L	-	-	-	UvrD-like helicase C-terminal domain
PIOLMLDC_00437	1.09e-05	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K03491	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PIOLMLDC_00439	2.65e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_00441	2.8e-92	-	-	-	S	-	-	-	HIRAN
PIOLMLDC_00442	2.63e-180	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
PIOLMLDC_00444	5.2e-161	-	-	-	-	-	-	-	-
PIOLMLDC_00445	8.58e-103	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PIOLMLDC_00446	2.45e-71	-	-	-	-	-	-	-	-
PIOLMLDC_00447	2.45e-89	-	-	-	-	-	-	-	-
PIOLMLDC_00448	4.69e-86	-	-	-	S	-	-	-	Domain of unknown function DUF1828
PIOLMLDC_00449	1.28e-153	-	-	-	S	-	-	-	Rib/alpha-like repeat
PIOLMLDC_00450	0.0	-	-	-	L	-	-	-	Transposase
PIOLMLDC_00451	2.03e-09	-	-	-	-	-	-	-	-
PIOLMLDC_00452	3.4e-311	yagE	-	-	E	-	-	-	amino acid
PIOLMLDC_00453	2.23e-149	-	-	-	GM	-	-	-	NmrA-like family
PIOLMLDC_00454	7.48e-192	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
PIOLMLDC_00455	8.71e-133	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
PIOLMLDC_00456	3.93e-220	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
PIOLMLDC_00457	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PIOLMLDC_00458	7.29e-304	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PIOLMLDC_00459	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PIOLMLDC_00460	6.85e-226	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PIOLMLDC_00461	7.14e-185	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
PIOLMLDC_00462	8.03e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PIOLMLDC_00463	3.88e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PIOLMLDC_00464	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PIOLMLDC_00465	7.45e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PIOLMLDC_00466	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PIOLMLDC_00467	2.8e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PIOLMLDC_00468	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PIOLMLDC_00469	9.56e-211	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PIOLMLDC_00470	2.64e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PIOLMLDC_00471	1.95e-82	ribT	-	-	K	ko:K02859	-	ko00000	acetyltransferase
PIOLMLDC_00472	2.9e-171	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PIOLMLDC_00473	1.59e-136	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PIOLMLDC_00474	3.25e-164	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PIOLMLDC_00475	3.89e-106	-	-	-	M	-	-	-	Lysin motif
PIOLMLDC_00476	7.74e-124	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PIOLMLDC_00477	1.78e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PIOLMLDC_00478	6.93e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PIOLMLDC_00479	1.28e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PIOLMLDC_00480	1.37e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PIOLMLDC_00481	1.21e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PIOLMLDC_00482	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	DEAD/DEAH box helicase
PIOLMLDC_00483	4.14e-175	-	-	-	S	ko:K06926	-	ko00000	AAA domain, putative AbiEii toxin, Type IV TA system
PIOLMLDC_00484	1.2e-54	-	-	-	S	-	-	-	RloB-like protein
PIOLMLDC_00486	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
PIOLMLDC_00487	6.68e-115	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
PIOLMLDC_00488	6.06e-98	-	-	-	K	-	-	-	SIR2-like domain
PIOLMLDC_00489	4.12e-254	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00491	2.57e-05	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PIOLMLDC_00493	3.45e-70	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PIOLMLDC_00494	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PIOLMLDC_00495	1.32e-76	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
PIOLMLDC_00496	4.7e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIOLMLDC_00497	6.74e-287	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PIOLMLDC_00498	7.97e-147	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PIOLMLDC_00499	3.01e-192	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PIOLMLDC_00500	3.74e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PIOLMLDC_00501	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PIOLMLDC_00502	3.46e-204	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PIOLMLDC_00503	1.09e-172	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIOLMLDC_00504	4.34e-199	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PIOLMLDC_00505	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PIOLMLDC_00506	1.97e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PIOLMLDC_00507	1.32e-222	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
PIOLMLDC_00508	1.1e-114	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PIOLMLDC_00509	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PIOLMLDC_00510	1.38e-227	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PIOLMLDC_00511	1.06e-127	-	-	-	K	-	-	-	LysR substrate binding domain
PIOLMLDC_00512	5.82e-130	-	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
PIOLMLDC_00514	3.54e-94	-	-	-	-	-	-	-	-
PIOLMLDC_00515	2.53e-264	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIOLMLDC_00516	6.18e-214	-	-	-	S	-	-	-	Conserved hypothetical protein 698
PIOLMLDC_00517	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PIOLMLDC_00518	8.45e-106	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
PIOLMLDC_00519	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PIOLMLDC_00520	2.8e-172	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PIOLMLDC_00521	4.4e-263	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PIOLMLDC_00522	4.86e-33	-	-	-	-	-	-	-	-
PIOLMLDC_00523	7.81e-82	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PIOLMLDC_00524	6.45e-45	-	-	-	S	-	-	-	Transposase C of IS166 homeodomain
PIOLMLDC_00525	1.4e-299	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PIOLMLDC_00526	1.72e-143	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PIOLMLDC_00527	9.15e-11	-	-	-	S	-	-	-	reductase
PIOLMLDC_00528	2.1e-21	-	-	-	S	-	-	-	reductase
PIOLMLDC_00529	6.22e-140	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
PIOLMLDC_00530	3.45e-150	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PIOLMLDC_00531	5.88e-163	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PIOLMLDC_00532	1.97e-310	-	-	-	T	-	-	-	GHKL domain
PIOLMLDC_00533	9.23e-28	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIOLMLDC_00534	4.12e-254	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00535	3.61e-20	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIOLMLDC_00536	1.68e-38	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PIOLMLDC_00537	1.87e-65	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
PIOLMLDC_00538	3.7e-131	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PIOLMLDC_00539	4.44e-313	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PIOLMLDC_00540	1.52e-54	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIOLMLDC_00541	2.71e-235	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PIOLMLDC_00542	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PIOLMLDC_00543	4.31e-315	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PIOLMLDC_00544	2.94e-108	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PIOLMLDC_00545	8.65e-243	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PIOLMLDC_00546	4.11e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PIOLMLDC_00547	3.97e-182	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PIOLMLDC_00548	6.1e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PIOLMLDC_00549	1.18e-250	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PIOLMLDC_00550	2.05e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PIOLMLDC_00551	4.72e-284	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PIOLMLDC_00552	2.29e-292	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PIOLMLDC_00553	5.72e-104	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PIOLMLDC_00554	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PIOLMLDC_00555	1.02e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIOLMLDC_00556	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PIOLMLDC_00557	6.38e-179	-	-	-	H	-	-	-	Nodulation protein S (NodS)
PIOLMLDC_00558	0.000705	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PIOLMLDC_00559	3.72e-238	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PIOLMLDC_00560	6.58e-28	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PIOLMLDC_00561	2.24e-176	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PIOLMLDC_00562	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
PIOLMLDC_00564	1.89e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PIOLMLDC_00565	1.22e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PIOLMLDC_00566	8.96e-101	-	-	-	S	-	-	-	Cupin domain
PIOLMLDC_00567	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PIOLMLDC_00568	3.93e-94	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PIOLMLDC_00569	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
PIOLMLDC_00570	5.24e-138	-	-	-	C	-	-	-	Aldo keto reductase
PIOLMLDC_00571	2.26e-22	lysR	-	-	K	-	-	-	Transcriptional regulator
PIOLMLDC_00572	1.92e-215	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
PIOLMLDC_00573	3.77e-218	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
PIOLMLDC_00574	1.42e-39	-	-	-	-	-	-	-	-
PIOLMLDC_00575	4.83e-145	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
PIOLMLDC_00576	3.14e-63	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PIOLMLDC_00577	3.73e-150	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PIOLMLDC_00578	1.18e-292	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIOLMLDC_00579	1.28e-195	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIOLMLDC_00580	1.04e-211	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PIOLMLDC_00581	5.54e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
PIOLMLDC_00582	1.89e-148	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIOLMLDC_00583	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIOLMLDC_00584	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PIOLMLDC_00585	5.65e-229	-	-	-	K	-	-	-	Transcriptional regulator
PIOLMLDC_00586	4.97e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PIOLMLDC_00587	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PIOLMLDC_00588	9.62e-142	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PIOLMLDC_00589	7.69e-159	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PIOLMLDC_00590	2.65e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_00591	1.63e-259	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PIOLMLDC_00592	1.05e-196	lysR	-	-	K	-	-	-	Transcriptional regulator
PIOLMLDC_00593	1.18e-197	-	-	-	-	-	-	-	-
PIOLMLDC_00594	3.19e-208	-	-	-	S	-	-	-	EDD domain protein, DegV family
PIOLMLDC_00595	1.32e-84	-	-	-	-	-	-	-	-
PIOLMLDC_00596	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PIOLMLDC_00597	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PIOLMLDC_00598	7.35e-249	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PIOLMLDC_00599	2.37e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PIOLMLDC_00600	7.17e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PIOLMLDC_00601	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PIOLMLDC_00602	7.27e-73	-	-	-	-	-	-	-	-
PIOLMLDC_00603	2.79e-224	degV1	-	-	S	-	-	-	DegV family
PIOLMLDC_00604	2.51e-284	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
PIOLMLDC_00605	1.17e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIOLMLDC_00606	4.43e-273	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PIOLMLDC_00607	2.77e-94	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PIOLMLDC_00608	3.65e-133	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PIOLMLDC_00609	3.06e-147	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PIOLMLDC_00610	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PIOLMLDC_00611	4.12e-254	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00612	6.6e-128	-	-	-	-	-	-	-	-
PIOLMLDC_00613	1.4e-261	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00614	2.72e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PIOLMLDC_00615	3.29e-147	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PIOLMLDC_00616	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PIOLMLDC_00617	1.32e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PIOLMLDC_00618	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PIOLMLDC_00619	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PIOLMLDC_00620	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PIOLMLDC_00621	7.55e-212	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
PIOLMLDC_00622	4.78e-223	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PIOLMLDC_00623	4.33e-260	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PIOLMLDC_00624	9.12e-238	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PIOLMLDC_00625	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIOLMLDC_00626	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIOLMLDC_00627	4.25e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_00628	1.71e-13	rnhA	3.1.26.4	-	L	ko:K03469,ko:K06993	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Caulimovirus viroplasmin
PIOLMLDC_00629	5.91e-146	-	-	-	G	-	-	-	Transmembrane secretion effector
PIOLMLDC_00630	1.12e-39	-	-	-	G	-	-	-	Transmembrane secretion effector
PIOLMLDC_00631	1.26e-150	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
PIOLMLDC_00632	1.72e-190	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
PIOLMLDC_00633	2.78e-85	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PIOLMLDC_00634	7.5e-201	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIOLMLDC_00635	3.38e-105	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
PIOLMLDC_00636	2.25e-95	-	-	-	S	-	-	-	ASCH
PIOLMLDC_00637	1.15e-188	-	-	-	F	-	-	-	Phosphorylase superfamily
PIOLMLDC_00638	2.31e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
PIOLMLDC_00639	2.34e-148	-	-	-	F	-	-	-	Phosphorylase superfamily
PIOLMLDC_00640	7.77e-103	-	-	-	F	-	-	-	NUDIX domain
PIOLMLDC_00641	9.39e-211	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
PIOLMLDC_00642	1.07e-138	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PIOLMLDC_00643	2.18e-112	-	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase (GNAT) family
PIOLMLDC_00644	1.67e-69	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIOLMLDC_00645	7.92e-15	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIOLMLDC_00646	3.03e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
PIOLMLDC_00647	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIOLMLDC_00648	1.8e-56	-	-	-	-	-	-	-	-
PIOLMLDC_00649	4.45e-157	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIOLMLDC_00650	6.31e-79	-	-	-	-	-	-	-	-
PIOLMLDC_00651	2.64e-63	-	-	-	S	-	-	-	MazG-like family
PIOLMLDC_00652	8.11e-109	-	-	-	FG	-	-	-	HIT domain
PIOLMLDC_00653	2.34e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIOLMLDC_00654	1.14e-100	-	-	-	-	-	-	-	-
PIOLMLDC_00655	6.92e-96	-	-	-	-	-	-	-	-
PIOLMLDC_00656	2.14e-138	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PIOLMLDC_00657	2.01e-57	-	-	-	-	ko:K07473	-	ko00000,ko02048	-
PIOLMLDC_00658	8.69e-68	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
PIOLMLDC_00659	7.32e-64	-	-	-	-	-	-	-	-
PIOLMLDC_00660	4.17e-238	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00661	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIOLMLDC_00662	5.8e-101	yfhC	-	-	C	-	-	-	nitroreductase
PIOLMLDC_00663	1.92e-263	-	-	-	P	-	-	-	Major Facilitator Superfamily
PIOLMLDC_00664	2.18e-305	-	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIOLMLDC_00665	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIOLMLDC_00666	7.46e-47	-	-	-	P	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter
PIOLMLDC_00667	6.75e-226	-	-	-	V	-	-	-	(ABC) transporter
PIOLMLDC_00668	1.21e-188	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PIOLMLDC_00669	3.52e-15	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PIOLMLDC_00670	3.85e-259	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
PIOLMLDC_00671	3.82e-59	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
PIOLMLDC_00672	1.69e-13	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
PIOLMLDC_00673	6.31e-95	-	-	-	S	-	-	-	SnoaL-like domain
PIOLMLDC_00674	8.07e-148	-	-	-	C	-	-	-	nitroreductase
PIOLMLDC_00675	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PIOLMLDC_00676	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIOLMLDC_00677	6.64e-148	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_00678	1.11e-138	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
PIOLMLDC_00679	2.07e-262	-	-	-	M	-	-	-	Glycosyl transferases group 1
PIOLMLDC_00680	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PIOLMLDC_00681	2.22e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
PIOLMLDC_00682	3.27e-118	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIOLMLDC_00683	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PIOLMLDC_00684	9.89e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PIOLMLDC_00685	5.06e-298	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PIOLMLDC_00686	8.32e-227	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PIOLMLDC_00687	3.04e-119	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PIOLMLDC_00688	6.47e-214	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PIOLMLDC_00689	2.05e-165	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PIOLMLDC_00690	2.62e-152	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PIOLMLDC_00691	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PIOLMLDC_00692	3.69e-190	yxeH	-	-	S	-	-	-	hydrolase
PIOLMLDC_00693	2.66e-228	-	-	-	S	-	-	-	DUF218 domain
PIOLMLDC_00694	1.7e-66	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
PIOLMLDC_00695	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PIOLMLDC_00696	2.66e-222	-	-	-	-	-	-	-	-
PIOLMLDC_00697	4.99e-165	-	-	-	-	-	-	-	-
PIOLMLDC_00698	1e-131	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PIOLMLDC_00699	2.93e-30	-	-	-	-	-	-	-	-
PIOLMLDC_00700	1.97e-173	-	-	-	-	-	-	-	-
PIOLMLDC_00701	2e-174	-	-	-	-	-	-	-	-
PIOLMLDC_00702	7.68e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIOLMLDC_00703	1.22e-77	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PIOLMLDC_00704	2.66e-311	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PIOLMLDC_00705	1.11e-193	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PIOLMLDC_00706	4.62e-163	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PIOLMLDC_00707	2.29e-191	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_00708	8.01e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_00709	7.1e-152	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
PIOLMLDC_00710	6.84e-147	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
PIOLMLDC_00711	4.25e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_00712	1.01e-247	XK27_03350	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.87
PIOLMLDC_00713	2.95e-110	-	-	-	-	-	-	-	-
PIOLMLDC_00714	7.15e-95	-	-	-	K	ko:K03088	-	ko00000,ko03021	Psort location Cytoplasmic, score 8.87
PIOLMLDC_00715	9.9e-116	XK26_06155	-	-	K	-	-	-	Psort location Cytoplasmic, score
PIOLMLDC_00716	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	elongation factor G
PIOLMLDC_00717	4.04e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
PIOLMLDC_00718	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PIOLMLDC_00719	4.25e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_00720	9.86e-124	-	-	-	-	-	-	-	-
PIOLMLDC_00721	3.52e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PIOLMLDC_00722	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PIOLMLDC_00723	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PIOLMLDC_00724	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PIOLMLDC_00725	5.64e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PIOLMLDC_00726	6.75e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PIOLMLDC_00727	3.98e-113	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PIOLMLDC_00728	1.27e-222	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PIOLMLDC_00729	5.18e-75	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PIOLMLDC_00730	8.33e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PIOLMLDC_00731	1.99e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PIOLMLDC_00732	9.17e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIOLMLDC_00733	4.47e-198	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PIOLMLDC_00734	8.72e-155	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PIOLMLDC_00735	7.46e-201	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIOLMLDC_00736	1.14e-135	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PIOLMLDC_00737	5e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
PIOLMLDC_00738	1.09e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PIOLMLDC_00739	1.77e-280	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PIOLMLDC_00740	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PIOLMLDC_00741	9.01e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PIOLMLDC_00742	8.26e-96	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PIOLMLDC_00743	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PIOLMLDC_00744	1.91e-85	-	-	-	-	-	-	-	-
PIOLMLDC_00745	1.43e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PIOLMLDC_00746	3.09e-111	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PIOLMLDC_00747	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PIOLMLDC_00748	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PIOLMLDC_00749	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PIOLMLDC_00750	3.61e-244	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
PIOLMLDC_00751	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PIOLMLDC_00752	8.16e-213	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PIOLMLDC_00753	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PIOLMLDC_00754	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PIOLMLDC_00755	1.74e-117	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_00756	2.94e-238	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PIOLMLDC_00757	9.46e-200	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PIOLMLDC_00758	9.15e-92	-	-	-	L	-	-	-	nuclease
PIOLMLDC_00759	1.05e-175	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PIOLMLDC_00760	4.75e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
PIOLMLDC_00761	8.42e-263	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00762	1.69e-230	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PIOLMLDC_00763	9.7e-312	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIOLMLDC_00764	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PIOLMLDC_00765	2.94e-42	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PIOLMLDC_00766	1.43e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PIOLMLDC_00767	8.86e-133	-	-	-	I	-	-	-	PAP2 superfamily
PIOLMLDC_00768	5.5e-139	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIOLMLDC_00772	8.51e-50	-	-	-	-	-	-	-	-
PIOLMLDC_00774	0.0	-	-	-	LM	-	-	-	gp58-like protein
PIOLMLDC_00775	9.02e-69	-	-	-	-	-	-	-	-
PIOLMLDC_00776	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
PIOLMLDC_00777	2.55e-51	-	-	-	-	-	-	-	-
PIOLMLDC_00778	2.95e-87	-	-	-	-	-	-	-	-
PIOLMLDC_00779	5.59e-95	-	-	-	S	-	-	-	Phage tail tube protein, TTP
PIOLMLDC_00780	1.86e-72	-	-	-	-	-	-	-	-
PIOLMLDC_00781	8.43e-107	-	-	-	-	-	-	-	-
PIOLMLDC_00782	1.19e-68	-	-	-	-	-	-	-	-
PIOLMLDC_00783	6.18e-51	-	-	-	-	-	-	-	-
PIOLMLDC_00784	4.95e-246	-	-	-	S	-	-	-	Phage major capsid protein E
PIOLMLDC_00785	3.37e-79	-	-	-	-	-	-	-	-
PIOLMLDC_00786	3.29e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
PIOLMLDC_00788	8.47e-197	-	-	-	S	-	-	-	Phage Mu protein F like protein
PIOLMLDC_00789	4.58e-41	-	-	-	S	-	-	-	Cysteine protease Prp
PIOLMLDC_00790	6.48e-79	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PIOLMLDC_00791	5.59e-200	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_00792	1.14e-222	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
PIOLMLDC_00793	1.96e-315	-	-	-	S	-	-	-	Terminase-like family
PIOLMLDC_00794	1.77e-179	xtmA	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
PIOLMLDC_00797	1.12e-115	-	-	-	-	-	-	-	-
PIOLMLDC_00798	4.38e-27	-	-	-	-	-	-	-	-
PIOLMLDC_00799	1.37e-29	-	-	-	-	-	-	-	-
PIOLMLDC_00802	7.13e-42	-	-	-	-	-	-	-	-
PIOLMLDC_00803	6.92e-56	-	-	-	-	-	-	-	-
PIOLMLDC_00804	4.17e-77	-	-	-	L	-	-	-	Endodeoxyribonuclease RusA
PIOLMLDC_00805	3.27e-74	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
PIOLMLDC_00807	7.39e-25	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
PIOLMLDC_00811	1.7e-102	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
PIOLMLDC_00812	7.24e-115	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIOLMLDC_00814	2.69e-09	-	-	-	K	-	-	-	Helix-turn-helix domain
PIOLMLDC_00815	5.98e-80	-	-	-	S	-	-	-	IstB-like ATP binding protein
PIOLMLDC_00816	1.1e-47	-	-	-	S	-	-	-	Conserved phage C-terminus (Phg_2220_C)
PIOLMLDC_00817	3.24e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF1071)
PIOLMLDC_00818	1.64e-44	-	-	-	S	-	-	-	Siphovirus Gp157
PIOLMLDC_00819	2.29e-34	-	-	-	-	-	-	-	-
PIOLMLDC_00822	1.51e-18	-	-	-	-	-	-	-	-
PIOLMLDC_00823	2.67e-43	-	-	-	-	-	-	-	-
PIOLMLDC_00827	1.68e-38	-	-	-	-	-	-	-	-
PIOLMLDC_00828	2.78e-101	-	-	-	K	ko:K07741	-	ko00000	BRO family, N-terminal domain
PIOLMLDC_00829	0.000669	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIOLMLDC_00830	5.75e-37	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIOLMLDC_00831	1.58e-58	-	-	-	E	-	-	-	Zn peptidase
PIOLMLDC_00834	7.88e-34	-	-	-	-	-	-	-	-
PIOLMLDC_00835	6.66e-27	-	-	-	-	-	-	-	-
PIOLMLDC_00836	9.11e-30	-	-	-	-	-	-	-	-
PIOLMLDC_00837	4.18e-282	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIOLMLDC_00840	2.14e-195	lysR5	-	-	K	-	-	-	LysR substrate binding domain
PIOLMLDC_00841	2.65e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_00842	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PIOLMLDC_00843	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PIOLMLDC_00844	9.23e-124	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PIOLMLDC_00845	5.29e-239	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PIOLMLDC_00846	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIOLMLDC_00847	0.0	potE	-	-	E	-	-	-	Amino Acid
PIOLMLDC_00848	5.93e-124	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PIOLMLDC_00849	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PIOLMLDC_00850	5.2e-156	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
PIOLMLDC_00851	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PIOLMLDC_00852	7.02e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PIOLMLDC_00853	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PIOLMLDC_00854	9.65e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PIOLMLDC_00855	1.08e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PIOLMLDC_00856	1.25e-138	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIOLMLDC_00857	4.79e-22	ansR	-	-	K	-	-	-	Transcriptional regulator
PIOLMLDC_00863	1.59e-41	-	-	-	-	-	-	-	-
PIOLMLDC_00866	1.46e-121	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
PIOLMLDC_00867	4.06e-187	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00868	3.83e-37	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00869	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PIOLMLDC_00870	1.5e-226	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PIOLMLDC_00871	2.98e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PIOLMLDC_00872	4.75e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PIOLMLDC_00873	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PIOLMLDC_00874	1.32e-63	-	-	-	J	-	-	-	ribosomal protein
PIOLMLDC_00875	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PIOLMLDC_00876	1.57e-280	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PIOLMLDC_00877	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PIOLMLDC_00878	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIOLMLDC_00879	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PIOLMLDC_00880	1.09e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PIOLMLDC_00881	3.37e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PIOLMLDC_00882	5.91e-176	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PIOLMLDC_00883	2.02e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PIOLMLDC_00884	4.12e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PIOLMLDC_00885	8.74e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PIOLMLDC_00886	7.4e-181	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PIOLMLDC_00887	2.1e-247	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PIOLMLDC_00888	2.35e-151	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PIOLMLDC_00889	6.29e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PIOLMLDC_00890	1.71e-307	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_00891	6e-129	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_00892	2.53e-137	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_00893	1.39e-34	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_00894	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_00895	4.85e-41	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
PIOLMLDC_00896	1.99e-44	ynzC	-	-	S	-	-	-	UPF0291 protein
PIOLMLDC_00897	2.24e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PIOLMLDC_00898	5.69e-147	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
PIOLMLDC_00899	4.7e-91	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
PIOLMLDC_00900	2.32e-151	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PIOLMLDC_00901	2.61e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PIOLMLDC_00902	3.7e-175	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PIOLMLDC_00903	2.07e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PIOLMLDC_00904	1.37e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PIOLMLDC_00905	3.29e-290	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PIOLMLDC_00906	3.48e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PIOLMLDC_00907	2.16e-132	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIOLMLDC_00908	2.41e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PIOLMLDC_00909	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
PIOLMLDC_00910	3.9e-214	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PIOLMLDC_00911	7.21e-143	-	-	-	L	-	-	-	Resolvase, N terminal domain
PIOLMLDC_00912	9.4e-317	-	-	-	L	-	-	-	Probable transposase
PIOLMLDC_00913	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIOLMLDC_00914	6.74e-258	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PIOLMLDC_00915	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PIOLMLDC_00916	1.29e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PIOLMLDC_00917	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_00918	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_00919	2.15e-206	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_00920	6.12e-230	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_00921	1.33e-225	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIOLMLDC_00922	1.72e-244	oppD	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIOLMLDC_00923	1.53e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PIOLMLDC_00924	4.31e-232	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PIOLMLDC_00925	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PIOLMLDC_00926	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PIOLMLDC_00927	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PIOLMLDC_00928	6.36e-34	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PIOLMLDC_00929	1.06e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PIOLMLDC_00930	4.51e-155	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PIOLMLDC_00931	6.45e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PIOLMLDC_00932	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PIOLMLDC_00933	1.29e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PIOLMLDC_00934	1.74e-307	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PIOLMLDC_00935	9.69e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PIOLMLDC_00936	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PIOLMLDC_00937	3.3e-43	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PIOLMLDC_00938	3.6e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PIOLMLDC_00939	7.04e-63	-	-	-	-	-	-	-	-
PIOLMLDC_00940	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PIOLMLDC_00941	5.29e-199	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PIOLMLDC_00942	8.82e-207	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PIOLMLDC_00943	2.74e-46	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIOLMLDC_00944	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PIOLMLDC_00945	5.24e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PIOLMLDC_00946	1e-88	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PIOLMLDC_00947	7.32e-95	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PIOLMLDC_00948	1.73e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIOLMLDC_00949	4.5e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIOLMLDC_00950	9.89e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PIOLMLDC_00951	1.67e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PIOLMLDC_00952	1.9e-79	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
PIOLMLDC_00953	2.81e-194	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PIOLMLDC_00954	3.98e-271	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PIOLMLDC_00955	1.17e-17	-	-	-	-	-	-	-	-
PIOLMLDC_00956	1.08e-83	-	-	-	-	-	-	-	-
PIOLMLDC_00957	4.18e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PIOLMLDC_00958	4.07e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PIOLMLDC_00959	7.71e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PIOLMLDC_00960	3.96e-70	-	-	-	-	-	-	-	-
PIOLMLDC_00961	9.83e-155	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PIOLMLDC_00962	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
PIOLMLDC_00963	5.58e-226	-	-	-	P	-	-	-	Major Facilitator Superfamily
PIOLMLDC_00964	4.8e-221	-	-	-	I	-	-	-	Carboxylesterase family
PIOLMLDC_00965	7.32e-176	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIOLMLDC_00966	3.74e-192	-	-	-	GK	-	-	-	ROK family
PIOLMLDC_00967	1.26e-96	-	-	-	M	-	-	-	Sortase family
PIOLMLDC_00969	8.62e-28	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
PIOLMLDC_00970	5.22e-16	-	-	-	K	-	-	-	transcriptional regulator
PIOLMLDC_00972	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIOLMLDC_00973	1.22e-81	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PIOLMLDC_00974	3.39e-53	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_00975	8.2e-26	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_00976	3.34e-267	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIOLMLDC_00977	3.24e-102	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PIOLMLDC_00978	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PIOLMLDC_00979	7.6e-121	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PIOLMLDC_00980	2.71e-188	-	-	-	M	-	-	-	Glycosyl transferase family 2
PIOLMLDC_00981	8.04e-139	-	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
PIOLMLDC_00982	8.07e-91	-	-	-	-	-	-	-	-
PIOLMLDC_00983	1.02e-238	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00984	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PIOLMLDC_00986	1.23e-181	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PIOLMLDC_00987	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PIOLMLDC_00988	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PIOLMLDC_00989	3.85e-292	sptS	-	-	T	-	-	-	Histidine kinase
PIOLMLDC_00990	7.12e-150	dltr	-	-	K	-	-	-	response regulator
PIOLMLDC_00991	5.75e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
PIOLMLDC_00992	4.12e-254	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_00993	1.02e-100	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIOLMLDC_00994	1.68e-73	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIOLMLDC_00995	1.3e-90	-	-	-	O	-	-	-	OsmC-like protein
PIOLMLDC_00996	0.0	-	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PIOLMLDC_00997	6.12e-232	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_00998	2.45e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PIOLMLDC_00999	1.64e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PIOLMLDC_01000	1.21e-206	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PIOLMLDC_01001	1.36e-100	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PIOLMLDC_01002	8.81e-114	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
PIOLMLDC_01003	1.05e-274	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PIOLMLDC_01006	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01007	2.59e-276	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PIOLMLDC_01008	1.34e-175	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIOLMLDC_01009	2.81e-296	-	-	-	E	ko:K03294	-	ko00000	amino acid
PIOLMLDC_01010	2.11e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIOLMLDC_01011	4.03e-301	yhdP	-	-	S	-	-	-	Transporter associated domain
PIOLMLDC_01012	6.35e-160	-	-	-	-	-	-	-	-
PIOLMLDC_01013	5.43e-148	-	-	-	C	-	-	-	nitroreductase
PIOLMLDC_01014	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PIOLMLDC_01015	3.01e-180	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PIOLMLDC_01016	1.29e-70	-	-	-	S	-	-	-	Enterocin A Immunity
PIOLMLDC_01017	2.4e-172	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PIOLMLDC_01018	1.61e-223	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PIOLMLDC_01019	1.44e-159	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PIOLMLDC_01020	4.72e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PIOLMLDC_01021	4.68e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
PIOLMLDC_01022	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
PIOLMLDC_01023	1.04e-77	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PIOLMLDC_01024	8.28e-152	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PIOLMLDC_01025	1.98e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIOLMLDC_01026	4.68e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PIOLMLDC_01027	1.19e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PIOLMLDC_01028	8.44e-217	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PIOLMLDC_01029	9.53e-207	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PIOLMLDC_01030	1.13e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIOLMLDC_01031	2.51e-153	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01032	2.94e-66	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01033	1.38e-167	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01034	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01035	2.42e-201	-	-	-	S	-	-	-	Phospholipase, patatin family
PIOLMLDC_01036	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PIOLMLDC_01038	6.77e-71	-	-	-	S	-	-	-	Enterocin A Immunity
PIOLMLDC_01043	6.62e-33	-	-	-	S	-	-	-	Enterocin A Immunity
PIOLMLDC_01044	3.84e-124	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PIOLMLDC_01045	2.46e-216	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIOLMLDC_01046	2.13e-247	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PIOLMLDC_01047	7.09e-181	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PIOLMLDC_01048	1.02e-238	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01049	2.72e-284	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PIOLMLDC_01050	1.6e-290	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
PIOLMLDC_01052	2.24e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PIOLMLDC_01054	8.35e-110	-	-	-	S	-	-	-	Putative adhesin
PIOLMLDC_01055	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIOLMLDC_01056	5.81e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PIOLMLDC_01057	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PIOLMLDC_01058	1.68e-85	-	-	-	-	-	-	-	-
PIOLMLDC_01059	3.24e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01060	1.5e-142	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01061	3.69e-192	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_01062	6.35e-176	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01063	1.89e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_01064	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
PIOLMLDC_01065	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01066	5.97e-87	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PIOLMLDC_01067	8.7e-196	-	-	-	S	-	-	-	Alpha beta hydrolase
PIOLMLDC_01068	3.41e-278	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
PIOLMLDC_01069	0.0	-	-	-	E	-	-	-	Peptidase family C69
PIOLMLDC_01070	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PIOLMLDC_01071	4.28e-45	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PIOLMLDC_01072	4.61e-208	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PIOLMLDC_01073	1.1e-266	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
PIOLMLDC_01074	4.93e-166	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PIOLMLDC_01075	5.63e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01077	7.25e-265	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
PIOLMLDC_01078	7.2e-79	rmaE	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PIOLMLDC_01079	1.19e-36	-	-	-	-	-	-	-	-
PIOLMLDC_01080	5.12e-269	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
PIOLMLDC_01081	0.0	-	-	-	E	-	-	-	Amino acid permease
PIOLMLDC_01082	4.79e-308	-	-	-	E	-	-	-	amino acid
PIOLMLDC_01083	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
PIOLMLDC_01084	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIOLMLDC_01085	0.0	-	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Peptidase family C69
PIOLMLDC_01086	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Contains amino acid permease domain
PIOLMLDC_01087	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIOLMLDC_01088	0.0	-	-	-	E	-	-	-	Phospholipase B
PIOLMLDC_01089	1.15e-143	-	-	-	I	-	-	-	Acid phosphatase homologues
PIOLMLDC_01090	1.53e-216	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
PIOLMLDC_01091	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
PIOLMLDC_01092	0.0	-	-	-	C	-	-	-	FMN_bind
PIOLMLDC_01093	1.16e-202	-	-	-	K	-	-	-	LysR family
PIOLMLDC_01094	1.16e-57	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIOLMLDC_01095	1.21e-23	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIOLMLDC_01096	9.68e-308	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PIOLMLDC_01097	1.17e-157	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PIOLMLDC_01098	7.75e-35	-	-	-	S	-	-	-	PFAM Archaeal ATPase
PIOLMLDC_01099	1.23e-99	-	-	-	K	-	-	-	acetyltransferase
PIOLMLDC_01100	7.68e-23	-	-	-	-	-	-	-	-
PIOLMLDC_01103	1.81e-162	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PIOLMLDC_01104	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PIOLMLDC_01105	2.23e-113	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIOLMLDC_01106	5.21e-90	-	-	-	-	-	-	-	-
PIOLMLDC_01107	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PIOLMLDC_01108	3.15e-219	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PIOLMLDC_01109	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
PIOLMLDC_01110	9.83e-185	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PIOLMLDC_01111	2.1e-139	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
PIOLMLDC_01112	8.42e-263	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01113	8.38e-208	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PIOLMLDC_01114	1.73e-127	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PIOLMLDC_01115	2.07e-238	-	-	-	S	-	-	-	Bacteriocin helveticin-J
PIOLMLDC_01116	2.93e-263	-	-	-	P	-	-	-	Voltage gated chloride channel
PIOLMLDC_01117	6.68e-103	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PIOLMLDC_01118	5.25e-142	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
PIOLMLDC_01119	5.06e-160	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
PIOLMLDC_01120	1.02e-121	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PIOLMLDC_01122	1.05e-60	-	-	-	-	-	-	-	-
PIOLMLDC_01123	3.79e-221	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PIOLMLDC_01124	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PIOLMLDC_01125	1.13e-219	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PIOLMLDC_01126	1.14e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PIOLMLDC_01127	4.14e-176	-	-	-	-	-	-	-	-
PIOLMLDC_01128	1.72e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PIOLMLDC_01129	1.29e-210	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PIOLMLDC_01130	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PIOLMLDC_01131	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PIOLMLDC_01132	4.47e-146	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PIOLMLDC_01133	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PIOLMLDC_01134	8.3e-274	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PIOLMLDC_01140	5.77e-81	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
PIOLMLDC_01141	1.61e-224	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PIOLMLDC_01142	1.19e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PIOLMLDC_01143	2.53e-133	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PIOLMLDC_01144	2.82e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PIOLMLDC_01145	2.12e-119	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PIOLMLDC_01146	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PIOLMLDC_01147	1.15e-73	-	-	-	-	-	-	-	-
PIOLMLDC_01148	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PIOLMLDC_01149	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PIOLMLDC_01150	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
PIOLMLDC_01151	3.11e-224	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PIOLMLDC_01152	3.47e-267	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PIOLMLDC_01153	8.01e-66	-	-	-	-	-	-	-	-
PIOLMLDC_01154	2.92e-37	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PIOLMLDC_01155	1.41e-176	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PIOLMLDC_01156	1.39e-276	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PIOLMLDC_01157	2.08e-151	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PIOLMLDC_01158	4.82e-184	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PIOLMLDC_01159	1.68e-75	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIOLMLDC_01160	3.47e-15	-	-	-	K	-	-	-	transcriptional
PIOLMLDC_01161	6.34e-05	-	-	-	S	-	-	-	Helix-turn-helix domain
PIOLMLDC_01169	3.65e-90	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PIOLMLDC_01170	8.93e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PIOLMLDC_01171	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIOLMLDC_01172	1.61e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
PIOLMLDC_01173	3.49e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PIOLMLDC_01174	1.18e-94	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PIOLMLDC_01175	1.08e-56	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PIOLMLDC_01176	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PIOLMLDC_01177	1.61e-294	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PIOLMLDC_01178	1.24e-234	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PIOLMLDC_01179	6.98e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PIOLMLDC_01180	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PIOLMLDC_01181	6.84e-75	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PIOLMLDC_01182	5.68e-237	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PIOLMLDC_01183	3.1e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PIOLMLDC_01184	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PIOLMLDC_01185	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PIOLMLDC_01186	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
PIOLMLDC_01188	9.69e-75	-	-	-	-	-	-	-	-
PIOLMLDC_01189	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PIOLMLDC_01190	3.69e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PIOLMLDC_01191	6.76e-168	-	-	-	S	-	-	-	membrane
PIOLMLDC_01192	5.72e-104	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIOLMLDC_01193	1.43e-42	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIOLMLDC_01194	8.82e-120	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Pfam:DUF303
PIOLMLDC_01195	5.47e-237	-	-	-	G	-	-	-	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01196	1.35e-116	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PIOLMLDC_01197	3.24e-132	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PIOLMLDC_01198	1.45e-150	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PIOLMLDC_01199	3.71e-110	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
PIOLMLDC_01200	1.87e-316	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
PIOLMLDC_01201	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PIOLMLDC_01202	2.13e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIOLMLDC_01203	3.11e-103	-	-	-	-	-	-	-	-
PIOLMLDC_01204	1.1e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIOLMLDC_01205	4.25e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01206	2.1e-18	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PIOLMLDC_01207	5.1e-185	-	-	-	G	-	-	-	Transmembrane secretion effector
PIOLMLDC_01208	4.6e-74	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIOLMLDC_01209	3.21e-289	bbsF_1	2.8.3.19	-	C	ko:K18702	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PIOLMLDC_01210	1.58e-23	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PIOLMLDC_01211	9.23e-63	-	-	-	L	ko:K07473	-	ko00000,ko02048	bacterial-type proximal promoter sequence-specific DNA binding
PIOLMLDC_01212	8.8e-93	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PIOLMLDC_01213	1.65e-161	-	-	-	L	-	-	-	oxidized base lesion DNA N-glycosylase activity
PIOLMLDC_01214	3.13e-311	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PIOLMLDC_01215	9.69e-317	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PIOLMLDC_01216	1.64e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIOLMLDC_01217	1.88e-307	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PIOLMLDC_01218	1.28e-136	-	-	-	-	-	-	-	-
PIOLMLDC_01219	7.05e-289	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01220	8.26e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PIOLMLDC_01221	2.06e-116	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PIOLMLDC_01222	7.98e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PIOLMLDC_01223	2.13e-111	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PIOLMLDC_01224	3.85e-179	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PIOLMLDC_01225	1.98e-197	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PIOLMLDC_01226	3.33e-78	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PIOLMLDC_01227	1.9e-195	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PIOLMLDC_01228	1.24e-68	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PIOLMLDC_01229	1.02e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PIOLMLDC_01230	3.03e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PIOLMLDC_01231	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PIOLMLDC_01232	5.45e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PIOLMLDC_01233	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PIOLMLDC_01234	1.68e-109	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PIOLMLDC_01235	1.65e-31	-	-	-	-	-	-	-	-
PIOLMLDC_01236	4.36e-142	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PIOLMLDC_01237	2.67e-43	-	-	-	-	-	-	-	-
PIOLMLDC_01238	2.21e-181	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
PIOLMLDC_01239	3.25e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PIOLMLDC_01240	1.78e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PIOLMLDC_01241	1.23e-182	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_01242	2.23e-150	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PIOLMLDC_01243	3.38e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01244	2.48e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PIOLMLDC_01245	1.89e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PIOLMLDC_01246	5.22e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PIOLMLDC_01247	8.06e-17	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PIOLMLDC_01248	1.48e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PIOLMLDC_01249	1.16e-240	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PIOLMLDC_01250	1.18e-291	-	-	-	G	-	-	-	Major Facilitator Superfamily
PIOLMLDC_01251	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PIOLMLDC_01252	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PIOLMLDC_01253	5.9e-46	-	-	-	-	-	-	-	-
PIOLMLDC_01254	1.07e-115	-	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factor activity
PIOLMLDC_01255	1.39e-180	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PIOLMLDC_01256	5.57e-104	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PIOLMLDC_01257	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PIOLMLDC_01258	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PIOLMLDC_01259	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PIOLMLDC_01260	6.34e-132	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
PIOLMLDC_01261	1.73e-101	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIOLMLDC_01262	2.6e-63	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIOLMLDC_01263	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PIOLMLDC_01264	4.32e-238	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PIOLMLDC_01265	6.28e-130	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PIOLMLDC_01267	1.76e-20	-	-	-	L	ko:K07483	-	ko00000	transposase activity
PIOLMLDC_01268	2.71e-07	-	-	-	UW	-	-	-	Tetratricopeptide repeat
PIOLMLDC_01270	2.88e-178	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PIOLMLDC_01271	3.78e-239	gtf1	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PIOLMLDC_01272	0.0	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PIOLMLDC_01273	1.25e-47	asp3	-	-	S	ko:K12270	-	ko00000,ko02044	Accessory Sec secretory system ASP3
PIOLMLDC_01274	8.12e-190	asp2	-	-	S	ko:K12269	-	ko00000,ko02044	Accessory Sec system GspB-transporter
PIOLMLDC_01275	6.69e-128	asp1	-	-	S	ko:K12268	-	ko00000,ko02044	Accessory Sec system protein Asp1
PIOLMLDC_01276	7.9e-131	secY2	-	-	U	-	-	-	Part of the accessory SecA2 SecY2 system specifically required for export of
PIOLMLDC_01277	6.02e-155	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01278	2.29e-194	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PIOLMLDC_01279	3.77e-72	-	-	-	S	-	-	-	glycosyl transferase family 2
PIOLMLDC_01280	1.55e-59	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PIOLMLDC_01281	2.11e-38	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PIOLMLDC_01282	2.62e-81	-	-	-	L	-	-	-	Transposase and inactivated derivatives
PIOLMLDC_01283	2.26e-84	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
PIOLMLDC_01284	3.18e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
PIOLMLDC_01285	3.3e-31	-	-	-	-	-	-	-	-
PIOLMLDC_01286	1.49e-07	-	-	-	UW	-	-	-	Tetratricopeptide repeat
PIOLMLDC_01288	7.42e-63	gtf2	-	-	M	-	-	-	A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PIOLMLDC_01289	5.59e-200	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_01290	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
PIOLMLDC_01291	1.2e-236	-	-	-	S	-	-	-	AAA domain
PIOLMLDC_01292	1.88e-157	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIOLMLDC_01293	2.39e-16	-	-	-	-	-	-	-	-
PIOLMLDC_01294	2.36e-51	-	-	-	-	-	-	-	-
PIOLMLDC_01295	8e-197	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PIOLMLDC_01296	4.17e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PIOLMLDC_01297	8.71e-164	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
PIOLMLDC_01298	8.91e-142	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PIOLMLDC_01299	8.93e-191	-	-	-	GM	-	-	-	NmrA-like family
PIOLMLDC_01300	1.12e-126	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PIOLMLDC_01301	1.98e-258	-	-	-	S	-	-	-	membrane
PIOLMLDC_01302	1.06e-149	-	-	-	GM	-	-	-	NAD(P)H-binding
PIOLMLDC_01303	3.4e-162	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
PIOLMLDC_01304	1.13e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PIOLMLDC_01305	1.08e-101	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PIOLMLDC_01306	1.02e-238	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01307	3.28e-187	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PIOLMLDC_01308	1.18e-179	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIOLMLDC_01309	1.41e-208	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIOLMLDC_01310	6.38e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PIOLMLDC_01311	1.91e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PIOLMLDC_01312	7.63e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIOLMLDC_01313	4.46e-81	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PIOLMLDC_01314	1.92e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PIOLMLDC_01315	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PIOLMLDC_01316	4.46e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PIOLMLDC_01317	4.87e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PIOLMLDC_01318	1.2e-299	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PIOLMLDC_01319	5.78e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PIOLMLDC_01320	3.44e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PIOLMLDC_01321	9.33e-107	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PIOLMLDC_01322	1.09e-74	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PIOLMLDC_01323	3.04e-122	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PIOLMLDC_01324	9.28e-89	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PIOLMLDC_01325	1.73e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIOLMLDC_01326	6.1e-124	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PIOLMLDC_01327	1.18e-46	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PIOLMLDC_01328	6.02e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PIOLMLDC_01329	7.74e-56	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PIOLMLDC_01330	2.92e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PIOLMLDC_01331	3e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PIOLMLDC_01332	3.69e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PIOLMLDC_01333	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PIOLMLDC_01334	6.08e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PIOLMLDC_01335	6.65e-197	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PIOLMLDC_01336	7.29e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PIOLMLDC_01337	1.57e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PIOLMLDC_01338	8.75e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PIOLMLDC_01339	5.22e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PIOLMLDC_01340	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PIOLMLDC_01341	8.05e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PIOLMLDC_01342	3.6e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PIOLMLDC_01343	8.54e-127	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
PIOLMLDC_01344	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIOLMLDC_01345	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PIOLMLDC_01346	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PIOLMLDC_01349	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PIOLMLDC_01350	2.26e-244	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PIOLMLDC_01351	1.92e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PIOLMLDC_01352	0.0	-	-	-	S	-	-	-	membrane
PIOLMLDC_01353	0.0	-	-	-	S	-	-	-	membrane
PIOLMLDC_01354	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PIOLMLDC_01355	9.85e-311	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PIOLMLDC_01356	1.33e-79	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
PIOLMLDC_01357	1.52e-77	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
PIOLMLDC_01358	3.62e-46	yabO	-	-	J	-	-	-	S4 domain protein
PIOLMLDC_01359	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PIOLMLDC_01360	2.58e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PIOLMLDC_01361	1.14e-231	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PIOLMLDC_01362	3.03e-158	-	-	-	S	-	-	-	(CBS) domain
PIOLMLDC_01363	5.18e-273	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PIOLMLDC_01364	1.75e-80	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PIOLMLDC_01365	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PIOLMLDC_01366	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PIOLMLDC_01367	1.23e-198	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01368	8.98e-55	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PIOLMLDC_01369	0.0	-	-	-	E	-	-	-	amino acid
PIOLMLDC_01370	1.48e-172	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01371	3.67e-184	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PIOLMLDC_01372	1.14e-230	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PIOLMLDC_01373	1.43e-290	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PIOLMLDC_01374	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PIOLMLDC_01375	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PIOLMLDC_01376	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PIOLMLDC_01377	3.87e-199	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
PIOLMLDC_01378	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIOLMLDC_01379	1.53e-16	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PIOLMLDC_01380	1.45e-151	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PIOLMLDC_01381	1.2e-101	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PIOLMLDC_01382	1.46e-42	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PIOLMLDC_01383	4.04e-103	-	-	-	-	-	-	-	-
PIOLMLDC_01384	7.02e-105	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
PIOLMLDC_01385	8.89e-39	-	-	-	-	-	-	-	-
PIOLMLDC_01386	9.7e-257	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
PIOLMLDC_01387	0.0	spxB	1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8	-	EH	ko:K00156,ko:K00158,ko:K01577,ko:K01652	ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PIOLMLDC_01388	0.0	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PIOLMLDC_01389	1.03e-122	-	-	-	-	-	-	-	-
PIOLMLDC_01390	3.49e-37	-	-	-	L	ko:K07483	-	ko00000	transposase activity
PIOLMLDC_01391	6.28e-130	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
PIOLMLDC_01392	2.29e-60	-	-	-	C	-	-	-	nadph quinone reductase
PIOLMLDC_01393	4.2e-91	-	-	-	C	-	-	-	nadph quinone reductase
PIOLMLDC_01394	4.53e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIOLMLDC_01395	1.33e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PIOLMLDC_01396	9.54e-97	-	-	-	K	-	-	-	LytTr DNA-binding domain
PIOLMLDC_01397	1.62e-177	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PIOLMLDC_01398	1.39e-195	-	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PIOLMLDC_01399	6.64e-280	-	-	-	S	-	-	-	Membrane
PIOLMLDC_01400	4.34e-85	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
PIOLMLDC_01401	2.31e-122	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIOLMLDC_01402	1.53e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PIOLMLDC_01403	5.94e-188	-	-	-	K	-	-	-	Helix-turn-helix
PIOLMLDC_01404	6.23e-123	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PIOLMLDC_01405	1.91e-144	-	-	-	K	-	-	-	transcriptional regulator
PIOLMLDC_01407	1.24e-218	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PIOLMLDC_01408	2.27e-20	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
PIOLMLDC_01409	1.93e-136	-	-	-	-	-	-	-	-
PIOLMLDC_01410	1.92e-171	-	-	-	D	-	-	-	ftsk spoiiie
PIOLMLDC_01414	0.0	-	-	-	V	-	-	-	DNA restriction-modification system
PIOLMLDC_01415	3.86e-126	-	-	-	-	-	-	-	-
PIOLMLDC_01416	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PIOLMLDC_01417	3.14e-160	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
PIOLMLDC_01418	6.78e-136	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PIOLMLDC_01419	3.23e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PIOLMLDC_01420	4.39e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PIOLMLDC_01421	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PIOLMLDC_01422	1.03e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PIOLMLDC_01423	7.07e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PIOLMLDC_01424	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIOLMLDC_01425	3.15e-219	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PIOLMLDC_01426	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
PIOLMLDC_01427	3.28e-196	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01428	0.0	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_01429	7.34e-290	malE	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIOLMLDC_01430	1.86e-266	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIOLMLDC_01431	3.66e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
PIOLMLDC_01432	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PIOLMLDC_01433	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PIOLMLDC_01434	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
PIOLMLDC_01435	5.01e-226	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
PIOLMLDC_01436	4.4e-220	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIOLMLDC_01437	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PIOLMLDC_01438	3.85e-196	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PIOLMLDC_01439	1.22e-48	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PIOLMLDC_01440	5.49e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PIOLMLDC_01441	4.59e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PIOLMLDC_01442	6.4e-189	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PIOLMLDC_01443	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PIOLMLDC_01444	5.01e-233	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PIOLMLDC_01445	2.42e-126	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PIOLMLDC_01446	6.82e-119	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
PIOLMLDC_01447	4.96e-247	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PIOLMLDC_01448	3.47e-148	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
PIOLMLDC_01450	6.6e-150	-	-	-	-	-	-	-	-
PIOLMLDC_01451	1.2e-203	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
PIOLMLDC_01452	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIOLMLDC_01453	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01454	3.44e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PIOLMLDC_01455	7.13e-56	-	-	-	-	-	-	-	-
PIOLMLDC_01456	3.56e-68	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
PIOLMLDC_01457	2.81e-175	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
PIOLMLDC_01458	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIOLMLDC_01459	1.07e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PIOLMLDC_01460	6.9e-167	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
PIOLMLDC_01461	1.85e-316	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01462	2.35e-107	-	-	-	-	-	-	-	-
PIOLMLDC_01463	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIOLMLDC_01464	5.25e-97	-	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PIOLMLDC_01465	3.85e-98	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PIOLMLDC_01466	1.06e-58	-	-	-	-	-	-	-	-
PIOLMLDC_01467	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PIOLMLDC_01468	5.93e-156	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PIOLMLDC_01469	0.0	pepC1	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PIOLMLDC_01471	7.25e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PIOLMLDC_01472	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
PIOLMLDC_01473	3.45e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PIOLMLDC_01474	1.59e-268	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIOLMLDC_01475	9.65e-218	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
PIOLMLDC_01476	3.83e-196	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PIOLMLDC_01477	6.21e-152	-	-	-	-	-	-	-	-
PIOLMLDC_01478	7.72e-228	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PIOLMLDC_01479	9.65e-95	-	-	-	S	-	-	-	GtrA-like protein
PIOLMLDC_01480	4.38e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PIOLMLDC_01481	6.15e-62	-	-	-	S	-	-	-	HicB_like antitoxin of bacterial toxin-antitoxin system
PIOLMLDC_01482	2.23e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PIOLMLDC_01483	2.4e-97	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PIOLMLDC_01484	6.79e-184	-	-	-	-	-	-	-	-
PIOLMLDC_01485	1.38e-180	-	-	-	-	-	-	-	-
PIOLMLDC_01486	1.01e-228	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
PIOLMLDC_01487	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PIOLMLDC_01488	1.13e-184	-	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PIOLMLDC_01489	0.0	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PIOLMLDC_01490	0.0	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PIOLMLDC_01491	3.38e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
PIOLMLDC_01492	3.24e-14	-	-	-	-	-	-	-	-
PIOLMLDC_01493	5.83e-176	-	-	-	-	-	-	-	-
PIOLMLDC_01494	4.33e-95	-	-	-	-	-	-	-	-
PIOLMLDC_01495	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PIOLMLDC_01496	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PIOLMLDC_01497	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PIOLMLDC_01498	3.35e-287	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01499	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PIOLMLDC_01500	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PIOLMLDC_01501	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIOLMLDC_01502	7.3e-216	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PIOLMLDC_01503	1.33e-174	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIOLMLDC_01504	0.0	-	-	-	D	-	-	-	transport
PIOLMLDC_01505	2.95e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
PIOLMLDC_01506	7.1e-291	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
PIOLMLDC_01507	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
PIOLMLDC_01508	6.48e-136	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PIOLMLDC_01509	1.51e-177	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PIOLMLDC_01510	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PIOLMLDC_01511	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PIOLMLDC_01512	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PIOLMLDC_01513	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PIOLMLDC_01514	9.7e-109	-	-	-	-	-	-	-	-
PIOLMLDC_01515	8.69e-189	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_01516	3.17e-169	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_01517	1.28e-181	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
PIOLMLDC_01518	1.16e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
PIOLMLDC_01520	3.49e-113	usp5	-	-	T	-	-	-	universal stress protein
PIOLMLDC_01521	1.45e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIOLMLDC_01522	1.38e-166	-	-	-	K	-	-	-	UTRA domain
PIOLMLDC_01523	5.05e-128	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PIOLMLDC_01524	3.15e-113	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
PIOLMLDC_01525	5.08e-282	-	-	-	S	-	-	-	zinc-ribbon domain
PIOLMLDC_01526	7.64e-88	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PIOLMLDC_01527	1.02e-190	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIOLMLDC_01528	8.1e-191	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIOLMLDC_01529	1.13e-108	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIOLMLDC_01530	1.47e-288	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PIOLMLDC_01531	1.27e-270	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
PIOLMLDC_01532	3.01e-164	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PIOLMLDC_01533	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PIOLMLDC_01534	6.18e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIOLMLDC_01535	3.26e-155	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PIOLMLDC_01536	1.16e-215	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PIOLMLDC_01537	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PIOLMLDC_01538	1.09e-141	-	-	-	-	-	-	-	-
PIOLMLDC_01539	1.3e-263	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PIOLMLDC_01540	0.0	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
PIOLMLDC_01541	8.05e-162	-	-	-	-	-	-	-	-
PIOLMLDC_01542	1.01e-148	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIOLMLDC_01543	1.67e-307	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PIOLMLDC_01544	6.1e-230	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PIOLMLDC_01545	2.78e-82	-	-	-	-	-	-	-	-
PIOLMLDC_01546	3.44e-161	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PIOLMLDC_01547	9.16e-203	epsV	-	-	S	-	-	-	glycosyl transferase family 2
PIOLMLDC_01548	1.66e-219	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PIOLMLDC_01550	2.63e-178	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PIOLMLDC_01551	3.37e-221	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIOLMLDC_01552	5.18e-159	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
PIOLMLDC_01553	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PIOLMLDC_01554	1.28e-103	-	-	-	-	-	-	-	-
PIOLMLDC_01555	1.45e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
PIOLMLDC_01556	6.09e-113	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
PIOLMLDC_01557	3.12e-78	terC	-	-	P	-	-	-	Integral membrane protein TerC family
PIOLMLDC_01558	3.72e-63	terC	-	-	P	-	-	-	Integral membrane protein TerC family
PIOLMLDC_01559	1.38e-82	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PIOLMLDC_01560	2.52e-148	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PIOLMLDC_01561	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01562	4.83e-177	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01563	5.01e-61	-	-	-	-	-	-	-	-
PIOLMLDC_01564	1.92e-208	-	-	-	L	-	-	-	HNH nucleases
PIOLMLDC_01565	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PIOLMLDC_01566	4.68e-259	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
PIOLMLDC_01567	1.13e-306	-	-	-	M	-	-	-	Glycosyl transferase
PIOLMLDC_01569	7.98e-154	-	-	-	-	-	-	-	-
PIOLMLDC_01570	1.14e-23	-	-	-	-	-	-	-	-
PIOLMLDC_01571	3.87e-83	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIOLMLDC_01572	2.02e-234	ysdE	-	-	P	-	-	-	Citrate transporter
PIOLMLDC_01573	8.93e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PIOLMLDC_01574	4.2e-209	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
PIOLMLDC_01575	1.76e-207	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIOLMLDC_01576	7.94e-128	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PIOLMLDC_01577	5.38e-307	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01578	2.68e-143	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
PIOLMLDC_01579	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PIOLMLDC_01580	6.78e-236	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PIOLMLDC_01581	1.76e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PIOLMLDC_01582	1.62e-190	yycI	-	-	S	-	-	-	YycH protein
PIOLMLDC_01583	0.0	yycH	-	-	S	-	-	-	YycH protein
PIOLMLDC_01584	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PIOLMLDC_01585	2.13e-167	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PIOLMLDC_01587	4.3e-315	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIOLMLDC_01589	3.43e-189	-	-	-	I	-	-	-	Acyl-transferase
PIOLMLDC_01590	2.52e-199	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
PIOLMLDC_01591	8.41e-235	-	-	-	M	-	-	-	Glycosyl transferase family 8
PIOLMLDC_01592	2.24e-239	-	-	-	M	-	-	-	Glycosyl transferase family 8
PIOLMLDC_01593	3.48e-212	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
PIOLMLDC_01594	1.45e-313	-	-	-	P	-	-	-	Major Facilitator Superfamily
PIOLMLDC_01595	8.11e-315	-	-	-	P	-	-	-	Major Facilitator Superfamily
PIOLMLDC_01596	3.19e-239	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
PIOLMLDC_01597	5.19e-111	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
PIOLMLDC_01598	8.35e-229	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PIOLMLDC_01599	1.09e-171	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PIOLMLDC_01600	1.02e-238	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01601	8.98e-309	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PIOLMLDC_01602	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
PIOLMLDC_01603	3.62e-216	-	-	-	K	-	-	-	LysR substrate binding domain
PIOLMLDC_01604	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PIOLMLDC_01605	3.15e-219	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
PIOLMLDC_01606	0.000673	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
PIOLMLDC_01607	0.0	-	-	-	S	-	-	-	domain, Protein
PIOLMLDC_01608	1.59e-245	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PIOLMLDC_01609	5.16e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PIOLMLDC_01610	1.61e-271	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PIOLMLDC_01611	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
PIOLMLDC_01612	4.56e-226	ydbI	-	-	K	-	-	-	AI-2E family transporter
PIOLMLDC_01613	4.32e-37	-	-	-	-	-	-	-	-
PIOLMLDC_01614	1.7e-173	-	-	-	S	-	-	-	Alpha beta hydrolase
PIOLMLDC_01615	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
PIOLMLDC_01616	3.75e-206	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PIOLMLDC_01617	1.83e-54	-	-	-	S	-	-	-	Transglycosylase associated protein
PIOLMLDC_01618	6.11e-20	-	-	-	S	-	-	-	CsbD-like
PIOLMLDC_01619	1.22e-261	XK27_02480	-	-	EGP	-	-	-	Major facilitator Superfamily
PIOLMLDC_01620	1.46e-135	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
PIOLMLDC_01621	2.99e-107	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
PIOLMLDC_01622	3.53e-310	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PIOLMLDC_01623	0.0	fusA1	-	-	J	-	-	-	elongation factor G
PIOLMLDC_01624	3.07e-43	-	-	-	K	-	-	-	Helix-turn-helix domain
PIOLMLDC_01625	4.17e-238	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01626	2.85e-110	-	-	-	K	-	-	-	Helix-turn-helix domain
PIOLMLDC_01627	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIOLMLDC_01628	1.07e-23	-	-	-	-	-	-	-	-
PIOLMLDC_01629	2.31e-193	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
PIOLMLDC_01630	8.76e-281	-	-	-	L	-	-	-	Transposase
PIOLMLDC_01631	4.25e-290	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01632	3e-20	-	-	-	L	-	-	-	Transposase
PIOLMLDC_01633	4.52e-178	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PIOLMLDC_01634	8.36e-162	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PIOLMLDC_01635	7.46e-149	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PIOLMLDC_01636	4.23e-213	-	-	-	I	-	-	-	Acyltransferase
PIOLMLDC_01637	1.41e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
PIOLMLDC_01639	1.96e-308	steT	-	-	E	ko:K03294	-	ko00000	amino acid
PIOLMLDC_01640	7.82e-316	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIOLMLDC_01642	0.0	-	-	-	-	-	-	-	-
PIOLMLDC_01643	1.39e-279	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
PIOLMLDC_01644	1.27e-218	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
PIOLMLDC_01645	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PIOLMLDC_01646	3.31e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PIOLMLDC_01647	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PIOLMLDC_01648	1.42e-216	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PIOLMLDC_01649	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PIOLMLDC_01650	5.89e-109	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PIOLMLDC_01651	4.55e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PIOLMLDC_01652	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIOLMLDC_01653	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PIOLMLDC_01654	7.88e-267	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PIOLMLDC_01655	5.33e-30	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
PIOLMLDC_01656	1.46e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PIOLMLDC_01657	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PIOLMLDC_01658	6.59e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
PIOLMLDC_01659	8.89e-80	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PIOLMLDC_01660	4.86e-201	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PIOLMLDC_01661	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PIOLMLDC_01662	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PIOLMLDC_01663	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PIOLMLDC_01664	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PIOLMLDC_01665	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PIOLMLDC_01666	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PIOLMLDC_01668	3.13e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PIOLMLDC_01669	1.6e-73	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PIOLMLDC_01670	8.42e-263	-	-	-	L	-	-	-	COG2826 Transposase and inactivated derivatives, IS30 family
PIOLMLDC_01671	2.31e-222	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
PIOLMLDC_01672	1.2e-84	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PIOLMLDC_01673	1.61e-313	ynbB	-	-	P	-	-	-	aluminum resistance
PIOLMLDC_01674	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PIOLMLDC_01675	0.0	-	-	-	E	-	-	-	Amino acid permease
PIOLMLDC_01676	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
PIOLMLDC_01677	7.67e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
PIOLMLDC_01678	1.25e-85	-	-	-	S	-	-	-	Cupredoxin-like domain
PIOLMLDC_01679	3.95e-98	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
PIOLMLDC_01680	3.08e-115	-	-	-	-	-	-	-	-
PIOLMLDC_01681	1.09e-97	-	-	-	-	-	-	-	-
PIOLMLDC_01682	8.12e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
PIOLMLDC_01683	9.21e-56	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
PIOLMLDC_01684	5.3e-19	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
PIOLMLDC_01685	3.78e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIOLMLDC_01686	7.71e-294	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIOLMLDC_01687	3e-167	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PIOLMLDC_01688	6.61e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PIOLMLDC_01689	2.91e-295	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PIOLMLDC_01690	3.15e-157	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PIOLMLDC_01691	8.43e-155	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
PIOLMLDC_01692	1.56e-171	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PIOLMLDC_01693	8.49e-205	-	-	-	S	-	-	-	Aldo/keto reductase family
PIOLMLDC_01694	1.65e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PIOLMLDC_01695	1.63e-171	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PIOLMLDC_01696	4.41e-123	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PIOLMLDC_01697	3.43e-205	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
PIOLMLDC_01698	1.38e-132	-	-	-	S	-	-	-	Putative esterase
PIOLMLDC_01699	5.59e-250	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PIOLMLDC_01700	7.98e-148	gspK	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
PIOLMLDC_01701	3.27e-304	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01702	2.56e-189	-	-	-	V	-	-	-	Beta-lactamase
PIOLMLDC_01703	9.53e-243	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
PIOLMLDC_01704	2.34e-213	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
PIOLMLDC_01705	3.34e-224	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PIOLMLDC_01706	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PIOLMLDC_01707	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PIOLMLDC_01708	1.9e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PIOLMLDC_01709	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PIOLMLDC_01710	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01711	7.34e-251	-	-	-	S	-	-	-	DUF218 domain
PIOLMLDC_01712	1.33e-142	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PIOLMLDC_01713	3.46e-120	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PIOLMLDC_01714	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
PIOLMLDC_01717	1.31e-98	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
PIOLMLDC_01718	5.8e-146	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
PIOLMLDC_01719	1.37e-199	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
PIOLMLDC_01720	2.07e-155	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PIOLMLDC_01721	2.33e-47	-	-	-	-	-	-	-	-
PIOLMLDC_01722	1.77e-201	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PIOLMLDC_01723	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PIOLMLDC_01724	1.05e-124	-	-	-	S	-	-	-	Putative adhesin
PIOLMLDC_01725	1.39e-257	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
PIOLMLDC_01726	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PIOLMLDC_01727	3.22e-109	ykuL	-	-	S	-	-	-	(CBS) domain
PIOLMLDC_01728	2.02e-269	-	-	-	S	-	-	-	Membrane
PIOLMLDC_01729	6.13e-52	-	-	-	-	-	-	-	-
PIOLMLDC_01730	9.7e-07	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
PIOLMLDC_01731	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIOLMLDC_01732	2.72e-302	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PIOLMLDC_01733	5.16e-50	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PIOLMLDC_01734	0.0	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PIOLMLDC_01735	2.3e-185	pbpX2	-	-	V	-	-	-	Beta-lactamase
PIOLMLDC_01736	1.97e-275	-	-	-	E	-	-	-	Major Facilitator Superfamily
PIOLMLDC_01737	2.11e-53	-	-	-	-	-	-	-	-
PIOLMLDC_01738	2.05e-311	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01739	1.69e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PIOLMLDC_01740	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
PIOLMLDC_01741	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
PIOLMLDC_01754	2.08e-151	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIOLMLDC_01755	1.19e-117	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
PIOLMLDC_01756	2.71e-234	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIOLMLDC_01757	1.23e-166	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PIOLMLDC_01758	4.25e-220	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PIOLMLDC_01759	8.6e-86	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
PIOLMLDC_01760	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PIOLMLDC_01761	2.21e-296	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PIOLMLDC_01762	4e-175	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PIOLMLDC_01763	2.44e-303	-	-	-	E	-	-	-	amino acid
PIOLMLDC_01764	7.01e-244	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
PIOLMLDC_01765	2.61e-205	-	-	-	EG	-	-	-	EamA-like transporter family
PIOLMLDC_01766	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PIOLMLDC_01767	3.43e-169	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PIOLMLDC_01768	6.89e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PIOLMLDC_01769	3.54e-182	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIOLMLDC_01770	3.71e-235	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
PIOLMLDC_01771	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PIOLMLDC_01772	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIOLMLDC_01773	6.45e-47	-	-	-	-	-	-	-	-
PIOLMLDC_01774	2.65e-290	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_01775	3.17e-247	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIOLMLDC_01776	5.59e-200	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
PIOLMLDC_01777	1.2e-201	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PIOLMLDC_01778	7.28e-117	ymdB	-	-	S	-	-	-	Macro domain protein
PIOLMLDC_01779	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PIOLMLDC_01780	1.39e-159	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PIOLMLDC_01781	3.03e-277	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PIOLMLDC_01782	4.69e-202	-	-	-	-	-	-	-	-
PIOLMLDC_01783	4.49e-93	aroD	1.1.1.25, 4.2.1.10	-	E	ko:K03785,ko:K13832	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	3-dehydroquinate dehydratase activity
PIOLMLDC_01784	7.26e-200	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
PIOLMLDC_01785	6.9e-197	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIOLMLDC_01786	1.59e-57	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PIOLMLDC_01787	3.69e-81	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PIOLMLDC_01788	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
PIOLMLDC_01789	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01790	2.16e-208	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PIOLMLDC_01791	2.6e-165	-	-	-	-	-	-	-	-
PIOLMLDC_01792	1.32e-66	-	-	-	-	-	-	-	-
PIOLMLDC_01793	1.5e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PIOLMLDC_01794	6.89e-180	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
PIOLMLDC_01795	5.95e-147	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PIOLMLDC_01796	9.58e-144	-	-	-	G	-	-	-	phosphoglycerate mutase
PIOLMLDC_01797	8.39e-114	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIOLMLDC_01798	1.38e-232	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PIOLMLDC_01799	8.96e-153	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01800	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIOLMLDC_01801	5.54e-50	-	-	-	-	-	-	-	-
PIOLMLDC_01802	5.69e-140	-	-	-	K	-	-	-	WHG domain
PIOLMLDC_01803	9.06e-125	-	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
PIOLMLDC_01804	4.45e-128	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
PIOLMLDC_01805	5e-253	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PIOLMLDC_01806	3.05e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PIOLMLDC_01807	2.69e-227	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PIOLMLDC_01808	3.16e-125	cvpA	-	-	S	-	-	-	Colicin V production protein
PIOLMLDC_01809	7.13e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PIOLMLDC_01810	7.73e-199	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PIOLMLDC_01811	3.52e-177	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PIOLMLDC_01812	2.58e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PIOLMLDC_01813	7.4e-58	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PIOLMLDC_01814	5.42e-254	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PIOLMLDC_01815	2.88e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PIOLMLDC_01816	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01817	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PIOLMLDC_01818	2.39e-156	vanR	-	-	K	-	-	-	response regulator
PIOLMLDC_01819	3.08e-265	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PIOLMLDC_01820	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PIOLMLDC_01821	5.06e-182	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PIOLMLDC_01822	1.79e-211	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01823	2.34e-283	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PIOLMLDC_01824	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
PIOLMLDC_01825	8e-176	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PIOLMLDC_01826	1.47e-213	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PIOLMLDC_01827	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PIOLMLDC_01828	0.0	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PIOLMLDC_01829	2.58e-181	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
PIOLMLDC_01830	3.28e-278	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01831	5.65e-276	-	-	-	G	-	-	-	Major Facilitator Superfamily
PIOLMLDC_01832	2.36e-289	-	-	-	L	-	-	-	Transposase
PIOLMLDC_01833	7.9e-72	-	-	-	L	-	-	-	Transposase and inactivated derivatives
PIOLMLDC_01834	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
PIOLMLDC_01835	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PIOLMLDC_01836	2.86e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PIOLMLDC_01837	2.51e-196	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_01838	1.19e-201	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_01839	7.56e-305	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIOLMLDC_01840	2.08e-204	lacR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PIOLMLDC_01841	2.56e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PIOLMLDC_01842	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PIOLMLDC_01843	1.19e-279	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PIOLMLDC_01844	2.5e-57	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
PIOLMLDC_01845	1.44e-81	-	-	-	G	-	-	-	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PIOLMLDC_01846	1.43e-162	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PIOLMLDC_01847	4.34e-152	-	-	-	C	-	-	-	nitroreductase
PIOLMLDC_01848	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
PIOLMLDC_01849	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
PIOLMLDC_01850	1.11e-235	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PIOLMLDC_01851	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
PIOLMLDC_01852	4.34e-237	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
PIOLMLDC_01853	1.84e-236	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PIOLMLDC_01854	1.22e-289	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01855	1.82e-31	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PIOLMLDC_01856	3.29e-203	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PIOLMLDC_01857	6.37e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PIOLMLDC_01858	1.03e-172	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PIOLMLDC_01859	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
PIOLMLDC_01860	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PIOLMLDC_01861	2.63e-265	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PIOLMLDC_01862	1.38e-50	-	-	-	-	-	-	-	-
PIOLMLDC_01863	4.49e-80	-	-	-	-	-	-	-	-
PIOLMLDC_01864	0.0	-	-	-	S	-	-	-	ABC transporter
PIOLMLDC_01865	3.73e-153	-	-	-	S	-	-	-	Putative threonine/serine exporter
PIOLMLDC_01866	2.64e-86	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PIOLMLDC_01867	1.05e-53	-	-	-	-	-	-	-	-
PIOLMLDC_01868	7.58e-79	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PIOLMLDC_01869	1.13e-103	-	-	-	-	-	-	-	-
PIOLMLDC_01870	4.83e-228	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PIOLMLDC_01871	1.35e-107	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PIOLMLDC_01872	2.23e-142	-	-	-	-	-	-	-	-
PIOLMLDC_01873	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
PIOLMLDC_01874	6.28e-57	-	-	-	-	-	-	-	-
PIOLMLDC_01875	6.55e-126	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PIOLMLDC_01876	1.32e-155	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PIOLMLDC_01877	5.19e-293	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PIOLMLDC_01878	6e-129	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01879	3.1e-114	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
PIOLMLDC_01880	3.69e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PIOLMLDC_01881	0.0	-	-	-	E	-	-	-	Amino Acid
PIOLMLDC_01882	2.68e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PIOLMLDC_01883	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PIOLMLDC_01884	4.36e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PIOLMLDC_01885	9.27e-36	-	-	-	-	-	-	-	-
PIOLMLDC_01886	1.65e-69	-	-	-	-	-	-	-	-
PIOLMLDC_01887	3.39e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PIOLMLDC_01888	1.75e-22	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PIOLMLDC_01889	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PIOLMLDC_01890	1.63e-164	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
PIOLMLDC_01891	3.25e-185	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PIOLMLDC_01892	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
PIOLMLDC_01894	3.42e-149	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
PIOLMLDC_01895	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PIOLMLDC_01896	2.68e-154	-	-	-	S	-	-	-	Peptidase_C39 like family
PIOLMLDC_01897	2.28e-133	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PIOLMLDC_01898	7.58e-210	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PIOLMLDC_01899	1.13e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PIOLMLDC_01900	1.24e-32	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIOLMLDC_01901	4.95e-130	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PIOLMLDC_01902	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PIOLMLDC_01903	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PIOLMLDC_01904	7.9e-195	-	-	-	EG	-	-	-	EamA-like transporter family
PIOLMLDC_01905	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PIOLMLDC_01906	3.18e-209	-	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PIOLMLDC_01907	3.23e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PIOLMLDC_01908	1.33e-186	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PIOLMLDC_01909	2.52e-36	-	-	-	S	-	-	-	Omega Transcriptional Repressor
PIOLMLDC_01910	1.01e-170	ermA	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylase
PIOLMLDC_01911	1.33e-23	-	-	-	-	-	-	-	-
PIOLMLDC_01912	3.27e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PIOLMLDC_01913	1.31e-267	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PIOLMLDC_01914	7.59e-305	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PIOLMLDC_01915	1.99e-181	-	-	-	S	-	-	-	PAS domain
PIOLMLDC_01916	1.15e-67	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PIOLMLDC_01917	4.68e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PIOLMLDC_01918	9.76e-120	-	-	-	S	-	-	-	PAS domain
PIOLMLDC_01919	2.26e-305	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PIOLMLDC_01920	1.07e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PIOLMLDC_01921	3.56e-145	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PIOLMLDC_01922	3.85e-195	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PIOLMLDC_01923	1.91e-233	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
PIOLMLDC_01924	3.37e-252	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PIOLMLDC_01925	1.25e-199	dkgB	-	-	S	-	-	-	reductase
PIOLMLDC_01926	1.06e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PIOLMLDC_01927	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PIOLMLDC_01928	8.41e-260	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PIOLMLDC_01929	3.57e-201	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PIOLMLDC_01930	2.39e-189	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PIOLMLDC_01931	1.62e-314	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
PIOLMLDC_01932	3.8e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PIOLMLDC_01933	4.76e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PIOLMLDC_01934	1.24e-98	yybA	-	-	K	-	-	-	Transcriptional regulator
PIOLMLDC_01935	2.76e-79	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PIOLMLDC_01936	2.02e-101	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PIOLMLDC_01937	1.86e-213	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
PIOLMLDC_01938	1.55e-204	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PIOLMLDC_01939	3.1e-125	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PIOLMLDC_01940	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PIOLMLDC_01941	1.26e-175	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PIOLMLDC_01942	2.14e-163	-	-	-	S	-	-	-	SNARE associated Golgi protein
PIOLMLDC_01943	3.53e-214	-	-	-	-	-	-	-	-
PIOLMLDC_01944	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PIOLMLDC_01945	1.5e-194	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
PIOLMLDC_01946	4.53e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PIOLMLDC_01947	2.53e-139	-	-	-	S	-	-	-	SNARE associated Golgi protein
PIOLMLDC_01948	7.38e-127	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PIOLMLDC_01949	3.74e-301	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)