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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
PHDLFKOG_00001	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PHDLFKOG_00002	4.16e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PHDLFKOG_00004	2.87e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
PHDLFKOG_00005	3.29e-258	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PHDLFKOG_00006	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHDLFKOG_00007	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PHDLFKOG_00008	6.04e-12	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
PHDLFKOG_00012	5.66e-08	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PHDLFKOG_00013	8.99e-99	-	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-strand binding protein family
PHDLFKOG_00014	2.26e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
PHDLFKOG_00015	4.51e-127	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PHDLFKOG_00016	3.26e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PHDLFKOG_00017	5.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
PHDLFKOG_00018	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome bd terminal oxidase subunit I
PHDLFKOG_00019	2.05e-233	-	-	-	C	-	-	-	Cytochrome bd terminal oxidase subunit II
PHDLFKOG_00020	7.17e-39	-	-	-	-	-	-	-	-
PHDLFKOG_00021	7.49e-138	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PHDLFKOG_00022	1.95e-107	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Best Blastp hit gi 7514214 pir G75157 'abc transporter, ATP-binding protein, puta tive PAB2069 - Pyrococcus abyssi (strain Orsay)' gi 5457852 emb CAB49342.1 '(AJ248284) ABC transporter, ATP-binding protein, puta tive Pyrococcus abyssi ', score 77, E-value 3.00E-13
PHDLFKOG_00023	9.5e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_00024	9.89e-243	-	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium Transporter Family
PHDLFKOG_00025	1.37e-269	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
PHDLFKOG_00026	3.23e-204	p40	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	CHAP domain
PHDLFKOG_00027	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PHDLFKOG_00028	3.54e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00029	6.57e-125	-	-	-	K	-	-	-	transcriptional regulator
PHDLFKOG_00030	2.94e-195	-	-	-	G	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PHDLFKOG_00031	2.32e-60	-	-	-	-	-	-	-	-
PHDLFKOG_00032	1.58e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PHDLFKOG_00033	8.48e-134	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PHDLFKOG_00034	1.86e-146	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
PHDLFKOG_00035	7.34e-72	-	-	-	-	-	-	-	-
PHDLFKOG_00037	1.45e-82	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHDLFKOG_00038	1.24e-265	pepD	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHDLFKOG_00039	1.7e-142	-	-	-	S	-	-	-	Membrane
PHDLFKOG_00040	3.12e-111	-	-	-	-	-	-	-	-
PHDLFKOG_00041	5.38e-68	-	-	-	-	-	-	-	-
PHDLFKOG_00042	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00043	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00045	5.33e-300	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PHDLFKOG_00046	3.24e-158	azlC	-	-	E	-	-	-	branched-chain amino acid
PHDLFKOG_00047	1.29e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
PHDLFKOG_00048	0.0	-	3.2.1.31	-	G	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 2 family
PHDLFKOG_00049	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
PHDLFKOG_00050	5.06e-152	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PHDLFKOG_00051	6.08e-227	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PHDLFKOG_00052	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
PHDLFKOG_00053	4.1e-276	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
PHDLFKOG_00054	0.0	uxuB	1.1.1.57	-	G	ko:K00040	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Mannitol dehydrogenase C-terminal domain
PHDLFKOG_00055	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 30 TIM-barrel domain
PHDLFKOG_00056	6.58e-293	-	-	-	G	-	-	-	Major Facilitator
PHDLFKOG_00057	1.9e-163	kdgR	-	-	K	-	-	-	FCD domain
PHDLFKOG_00058	1.74e-242	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PHDLFKOG_00059	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
PHDLFKOG_00060	9.4e-76	ps105	-	-	-	-	-	-	-
PHDLFKOG_00061	3.77e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
PHDLFKOG_00062	1e-306	-	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_00063	2.81e-279	-	3.1.1.83	-	I	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	ko00000,ko00001,ko01000	Alpha beta hydrolase
PHDLFKOG_00064	9.32e-154	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_00066	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
PHDLFKOG_00067	3.73e-137	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
PHDLFKOG_00068	2.75e-157	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
PHDLFKOG_00069	1.21e-309	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
PHDLFKOG_00070	1.3e-89	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
PHDLFKOG_00071	1.68e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
PHDLFKOG_00073	1.37e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PHDLFKOG_00074	1.96e-225	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHDLFKOG_00075	2.13e-136	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_00076	7.45e-279	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00077	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
PHDLFKOG_00078	1.04e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
PHDLFKOG_00079	6.78e-132	dpsB	-	-	P	-	-	-	Belongs to the Dps family
PHDLFKOG_00080	2.13e-150	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
PHDLFKOG_00082	2.81e-201	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PHDLFKOG_00083	0.0	-	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02770,ko:K02794,ko:K02795	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00084	1.99e-104	frvA	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00085	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
PHDLFKOG_00086	1.01e-179	-	-	-	K	-	-	-	SIS domain
PHDLFKOG_00087	0.0	-	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_00088	5.67e-200	bglK_1	-	-	GK	-	-	-	ROK family
PHDLFKOG_00090	2.89e-182	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PHDLFKOG_00091	7.93e-290	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PHDLFKOG_00092	2.84e-136	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
PHDLFKOG_00093	8.5e-170	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
PHDLFKOG_00094	6.58e-231	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PHDLFKOG_00096	0.0	-	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_00097	6.02e-143	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_00098	8.18e-151	-	-	-	-	-	-	-	-
PHDLFKOG_00099	1.39e-198	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type transport system involved in multi-copper enzyme maturation permease component
PHDLFKOG_00100	2.35e-136	-	-	-	-	-	-	-	-
PHDLFKOG_00101	5.89e-125	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_00103	2.26e-136	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase
PHDLFKOG_00104	1.18e-174	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PHDLFKOG_00105	3.74e-210	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PHDLFKOG_00106	6.84e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PHDLFKOG_00107	1.03e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PHDLFKOG_00108	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PHDLFKOG_00109	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PHDLFKOG_00110	5.72e-238	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PHDLFKOG_00111	5.83e-251	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PHDLFKOG_00112	8.13e-82	-	-	-	-	-	-	-	-
PHDLFKOG_00113	2.62e-95	-	-	-	L	-	-	-	NUDIX domain
PHDLFKOG_00114	5.16e-192	-	-	-	EG	-	-	-	EamA-like transporter family
PHDLFKOG_00115	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00116	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00118	2.24e-64	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
PHDLFKOG_00119	2.4e-137	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
PHDLFKOG_00120	1.95e-78	-	-	-	K	-	-	-	Tetracyclin repressor, C-terminal all-alpha domain
PHDLFKOG_00121	3.71e-68	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PHDLFKOG_00122	4.01e-99	-	-	-	P	-	-	-	ABC-2 family transporter protein
PHDLFKOG_00123	3.17e-126	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00124	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
PHDLFKOG_00125	4.7e-98	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PHDLFKOG_00126	3.57e-314	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
PHDLFKOG_00127	3.05e-282	-	-	-	-	-	-	-	-
PHDLFKOG_00128	0.0	pts32BC	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_00129	8.75e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PHDLFKOG_00130	8.98e-253	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
PHDLFKOG_00131	6.9e-200	yleF	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PHDLFKOG_00132	8.13e-137	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
PHDLFKOG_00133	9.01e-164	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00134	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PHDLFKOG_00135	2.94e-264	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
PHDLFKOG_00136	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PHDLFKOG_00138	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
PHDLFKOG_00139	4.21e-72	cadC5	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
PHDLFKOG_00140	7.11e-260	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_00141	1.34e-193	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHDLFKOG_00142	6.52e-36	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
PHDLFKOG_00143	5.45e-154	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_00144	3.78e-131	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PHDLFKOG_00145	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
PHDLFKOG_00146	1.43e-38	-	-	-	-	-	-	-	-
PHDLFKOG_00147	3.4e-64	-	-	-	-	-	-	-	-
PHDLFKOG_00148	2.48e-142	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
PHDLFKOG_00149	2e-238	yveB	-	-	I	-	-	-	PAP2 superfamily
PHDLFKOG_00150	2.16e-265	mccF	-	-	V	-	-	-	LD-carboxypeptidase
PHDLFKOG_00151	2.67e-56	-	-	-	-	-	-	-	-
PHDLFKOG_00152	1.15e-261	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
PHDLFKOG_00153	1.06e-53	-	-	-	-	-	-	-	-
PHDLFKOG_00154	1.05e-143	-	-	-	-	-	-	-	-
PHDLFKOG_00155	7.29e-290	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_00156	4.54e-111	-	-	-	-	-	-	-	-
PHDLFKOG_00157	8.02e-255	yclK	-	-	T	-	-	-	Histidine kinase
PHDLFKOG_00158	4.14e-155	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
PHDLFKOG_00159	6.05e-118	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
PHDLFKOG_00160	6.21e-241	ldhD3	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHDLFKOG_00161	4.97e-64	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00162	1.99e-69	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PHDLFKOG_00163	3.35e-111	-	-	-	-	-	-	-	-
PHDLFKOG_00164	0.0	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHDLFKOG_00165	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_00166	3.38e-169	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
PHDLFKOG_00167	9.23e-55	-	-	-	-	-	-	-	-
PHDLFKOG_00168	1.17e-75	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
PHDLFKOG_00169	2.83e-71	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
PHDLFKOG_00170	0.0	XK27_07275	-	-	S	ko:K06901	-	ko00000,ko02000	permease
PHDLFKOG_00171	3.44e-70	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
PHDLFKOG_00172	6.44e-239	mhqA	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHDLFKOG_00173	4.75e-57	-	-	-	-	-	-	-	-
PHDLFKOG_00174	9.29e-138	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PHDLFKOG_00175	0.0	-	-	-	-	-	-	-	-
PHDLFKOG_00177	8.2e-177	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PHDLFKOG_00178	3.3e-240	ynjC	-	-	S	-	-	-	Cell surface protein
PHDLFKOG_00180	0.0	-	-	-	L	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_00181	2e-191	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
PHDLFKOG_00182	9.43e-73	-	-	-	-	-	-	-	-
PHDLFKOG_00183	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PHDLFKOG_00184	1.7e-279	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHDLFKOG_00185	3.65e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
PHDLFKOG_00186	0.0	-	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
PHDLFKOG_00187	9.14e-205	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PHDLFKOG_00188	1.27e-308	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_00189	3.89e-203	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PHDLFKOG_00190	1.39e-174	-	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
PHDLFKOG_00191	0.0	bmr3	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_00194	3.47e-112	-	-	-	-	-	-	-	-
PHDLFKOG_00196	7.46e-61	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPase activity
PHDLFKOG_00197	3.79e-28	-	-	-	-	-	-	-	-
PHDLFKOG_00199	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
PHDLFKOG_00200	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PHDLFKOG_00201	1.65e-116	-	-	-	-	-	-	-	-
PHDLFKOG_00202	1.92e-149	-	-	-	-	-	-	-	-
PHDLFKOG_00203	6.5e-162	-	-	-	-	-	-	-	-
PHDLFKOG_00204	2.8e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_00205	2.2e-97	-	-	-	-	-	-	-	-
PHDLFKOG_00206	5.25e-106	-	-	-	S	-	-	-	NUDIX domain
PHDLFKOG_00207	2.66e-271	-	-	-	S	-	-	-	nuclear-transcribed mRNA catabolic process, no-go decay
PHDLFKOG_00208	0.0	fnq20	-	-	S	-	-	-	FAD-NAD(P)-binding
PHDLFKOG_00209	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PHDLFKOG_00210	6.18e-150	-	-	-	-	-	-	-	-
PHDLFKOG_00211	8.84e-274	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PHDLFKOG_00212	2.86e-183	yunE	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
PHDLFKOG_00213	1.85e-73	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
PHDLFKOG_00214	1.47e-07	-	-	-	-	-	-	-	-
PHDLFKOG_00215	5.12e-84	-	-	-	-	-	-	-	-
PHDLFKOG_00216	7.43e-69	-	-	-	-	-	-	-	-
PHDLFKOG_00217	2.23e-107	-	-	-	C	-	-	-	Flavodoxin
PHDLFKOG_00218	4.57e-49	-	-	-	-	-	-	-	-
PHDLFKOG_00219	4.87e-37	-	-	-	-	-	-	-	-
PHDLFKOG_00220	5.78e-219	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHDLFKOG_00221	1.87e-93	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
PHDLFKOG_00222	1.55e-51	-	-	-	S	-	-	-	Transglycosylase associated protein
PHDLFKOG_00223	1.68e-116	-	-	-	S	-	-	-	Protein conserved in bacteria
PHDLFKOG_00224	1.32e-39	-	-	-	-	-	-	-	-
PHDLFKOG_00225	1.62e-80	asp23	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PHDLFKOG_00226	3.02e-87	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PHDLFKOG_00227	2.73e-166	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PHDLFKOG_00228	4.96e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF969)
PHDLFKOG_00229	5.63e-186	-	-	-	S	-	-	-	Protein of unknown function (DUF979)
PHDLFKOG_00230	5.7e-153	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PHDLFKOG_00231	1.89e-133	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PHDLFKOG_00233	3.57e-165	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
PHDLFKOG_00234	2.32e-86	-	-	-	-	-	-	-	-
PHDLFKOG_00235	9.03e-173	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
PHDLFKOG_00236	5.2e-188	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PHDLFKOG_00237	3.67e-178	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
PHDLFKOG_00238	6.39e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
PHDLFKOG_00239	8.4e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
PHDLFKOG_00240	4.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PHDLFKOG_00241	2.39e-182	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
PHDLFKOG_00242	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHDLFKOG_00243	1.67e-152	-	-	-	-	-	-	-	-
PHDLFKOG_00244	1.68e-156	vanR	-	-	K	-	-	-	response regulator
PHDLFKOG_00245	1.45e-280	hpk31	-	-	T	-	-	-	Histidine kinase
PHDLFKOG_00246	5.54e-303	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
PHDLFKOG_00247	2.55e-111	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHDLFKOG_00248	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PHDLFKOG_00249	1.83e-180	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
PHDLFKOG_00250	1.93e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
PHDLFKOG_00251	1.13e-181	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	DeoR C terminal sensor domain
PHDLFKOG_00252	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PHDLFKOG_00253	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PHDLFKOG_00254	1.64e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PHDLFKOG_00255	6.58e-227	iolC	2.7.1.92	-	H	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PHDLFKOG_00256	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PHDLFKOG_00257	1.12e-245	iolG	1.1.1.18, 1.1.1.369	-	C	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PHDLFKOG_00258	1.01e-250	iolG2	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
PHDLFKOG_00259	2.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PHDLFKOG_00260	5.48e-202	iolJ	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PHDLFKOG_00261	1.75e-87	yodA	-	-	S	-	-	-	Tautomerase enzyme
PHDLFKOG_00262	1.2e-203	-	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
PHDLFKOG_00263	2.1e-215	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
PHDLFKOG_00264	5.62e-190	gntR	-	-	K	-	-	-	rpiR family
PHDLFKOG_00265	1.6e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
PHDLFKOG_00266	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
PHDLFKOG_00267	4.61e-270	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
PHDLFKOG_00268	3.08e-74	-	-	-	-	-	-	-	-
PHDLFKOG_00269	8.68e-169	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PHDLFKOG_00270	2.96e-173	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PHDLFKOG_00271	6.52e-215	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PHDLFKOG_00272	3.89e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
PHDLFKOG_00273	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
PHDLFKOG_00274	6.87e-256	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PHDLFKOG_00275	2.15e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PHDLFKOG_00276	4.98e-98	-	-	-	T	-	-	-	Sh3 type 3 domain protein
PHDLFKOG_00277	2.29e-175	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PHDLFKOG_00278	5.69e-189	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_00279	6.35e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PHDLFKOG_00280	4.9e-69	-	-	-	-	-	-	-	-
PHDLFKOG_00281	4.32e-138	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
PHDLFKOG_00282	2.04e-224	-	3.2.2.24	-	O	ko:K05521	-	ko00000,ko01000	ADP-ribosylglycohydrolase
PHDLFKOG_00283	0.0	-	-	-	S	-	-	-	ABC transporter
PHDLFKOG_00284	1.5e-178	ksgA	2.1.1.182, 2.1.1.197, 2.5.1.134	-	J	ko:K02169,ko:K02528,ko:K17216,ko:K17462	ko00270,ko00780,ko01100,ko01230,map00270,map00780,map01100,map01230	ko00000,ko00001,ko00002,ko01000,ko03009	rRNA (adenine-N6,N6-)-dimethyltransferase activity
PHDLFKOG_00285	1.45e-46	-	-	-	-	-	-	-	-
PHDLFKOG_00286	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PHDLFKOG_00288	2.96e-57	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PHDLFKOG_00289	1.14e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
PHDLFKOG_00290	5.92e-97	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PHDLFKOG_00291	4.62e-273	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
PHDLFKOG_00292	5.16e-192	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
PHDLFKOG_00293	8.13e-185	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
PHDLFKOG_00294	7.09e-179	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
PHDLFKOG_00295	6.48e-157	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_00296	6.94e-70	-	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
PHDLFKOG_00297	5.34e-214	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PHDLFKOG_00298	1.12e-303	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHDLFKOG_00299	2.32e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PHDLFKOG_00300	3.78e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PHDLFKOG_00301	3.14e-166	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
PHDLFKOG_00302	4.22e-216	p75	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
PHDLFKOG_00303	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
PHDLFKOG_00304	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
PHDLFKOG_00305	5.96e-185	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PHDLFKOG_00306	3.11e-75	lacF-1	2.7.1.207	-	G	ko:K02786	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PHDLFKOG_00307	4.73e-294	lacG	3.2.1.21, 3.2.1.85	-	G	ko:K01220,ko:K05350	ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_00308	1.1e-197	-	-	-	-	-	-	-	-
PHDLFKOG_00309	1.81e-150	-	-	-	-	-	-	-	-
PHDLFKOG_00310	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
PHDLFKOG_00311	3.9e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PHDLFKOG_00312	1.74e-111	-	-	-	-	-	-	-	-
PHDLFKOG_00313	0.0	manR	-	-	G	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00314	1.34e-88	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00315	1.31e-305	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_00316	1.66e-249	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
PHDLFKOG_00317	5.43e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PHDLFKOG_00318	1.15e-280	agaS	-	-	G	ko:K02082	-	ko00000,ko01000	SIS domain
PHDLFKOG_00319	5.31e-287	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHDLFKOG_00320	0.0	bgaC	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Glycosyl hydrolases family 35
PHDLFKOG_00321	3.25e-107	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_00322	2.07e-179	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PHDLFKOG_00323	3.66e-187	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PHDLFKOG_00324	1.11e-84	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PHDLFKOG_00325	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PHDLFKOG_00326	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHDLFKOG_00327	1.33e-292	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
PHDLFKOG_00328	3.79e-293	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PHDLFKOG_00329	2.08e-202	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PHDLFKOG_00330	7.48e-35	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PHDLFKOG_00331	0.0	-	-	-	U	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHDLFKOG_00332	2.02e-78	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00333	3.76e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PHDLFKOG_00334	1.17e-247	-	-	-	E	-	-	-	M42 glutamyl aminopeptidase
PHDLFKOG_00335	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00336	1.3e-298	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
PHDLFKOG_00337	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PHDLFKOG_00338	1.51e-152	-	-	-	S	ko:K03824	-	ko00000,ko01000	Acetyltransferase (GNAT) family
PHDLFKOG_00339	0.0	nisT	-	-	V	ko:K06147,ko:K20485	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	ABC transporter
PHDLFKOG_00340	4.39e-34	-	-	-	-	-	-	-	-
PHDLFKOG_00341	3.19e-49	-	-	-	-	-	-	-	-
PHDLFKOG_00342	4.57e-123	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
PHDLFKOG_00343	1.33e-311	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PHDLFKOG_00344	1.55e-141	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PHDLFKOG_00345	5.44e-163	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PHDLFKOG_00346	1.46e-106	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
PHDLFKOG_00347	6.35e-100	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PHDLFKOG_00348	7.84e-74	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PHDLFKOG_00349	5.6e-132	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PHDLFKOG_00350	4.28e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PHDLFKOG_00351	0.0	-	-	-	E	-	-	-	Amino acid permease
PHDLFKOG_00352	1.16e-239	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PHDLFKOG_00353	2.78e-80	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PHDLFKOG_00354	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PHDLFKOG_00355	2.36e-205	rbsC	-	-	U	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PHDLFKOG_00356	3.24e-204	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
PHDLFKOG_00357	2.71e-209	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PHDLFKOG_00358	3.31e-58	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
PHDLFKOG_00359	7.37e-48	-	-	-	-	-	-	-	-
PHDLFKOG_00363	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00364	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00365	8.27e-183	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
PHDLFKOG_00366	0.0	pbpC	-	-	M	ko:K21467	-	ko00000,ko01011	NTF2-like N-terminal transpeptidase domain
PHDLFKOG_00367	3.66e-67	-	-	-	-	-	-	-	-
PHDLFKOG_00368	9.81e-111	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PHDLFKOG_00369	1.54e-103	-	-	-	-	-	-	-	-
PHDLFKOG_00370	7.7e-79	-	-	-	-	-	-	-	-
PHDLFKOG_00371	5.52e-121	-	-	-	-	-	-	-	-
PHDLFKOG_00372	4.33e-98	-	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_00373	1.78e-152	-	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_00374	2.77e-89	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PHDLFKOG_00375	7.11e-135	-	-	-	-	-	-	-	-
PHDLFKOG_00376	4.94e-40	-	-	-	-	-	-	-	-
PHDLFKOG_00377	8.81e-204	-	-	-	GKT	-	-	-	transcriptional antiterminator
PHDLFKOG_00378	1.27e-61	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00379	4.22e-287	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_00380	4.79e-63	-	-	-	-	-	-	-	-
PHDLFKOG_00381	6.56e-192	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PHDLFKOG_00382	1.1e-112	-	-	-	S	-	-	-	Zeta toxin
PHDLFKOG_00383	7.6e-199	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
PHDLFKOG_00384	3.88e-271	dcuC	-	-	C	ko:K03326	-	ko00000,ko02000	Tripartite ATP-independent periplasmic transporter, DctM component
PHDLFKOG_00386	7.44e-153	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PHDLFKOG_00387	6.49e-111	-	-	-	G	-	-	-	DeoC/LacD family aldolase
PHDLFKOG_00388	8.81e-49	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PHDLFKOG_00389	4.02e-223	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
PHDLFKOG_00390	1.96e-117	fabG10	1.1.1.100, 1.3.1.28	-	IQ	ko:K00059,ko:K00216	ko00061,ko00333,ko00780,ko01040,ko01053,ko01100,ko01110,ko01130,ko01212,map00061,map00333,map00780,map01040,map01053,map01100,map01110,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
PHDLFKOG_00391	7.36e-159	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PHDLFKOG_00392	1.77e-198	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_00393	0.0	-	-	-	K	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00394	2.62e-198	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PHDLFKOG_00395	0.0	-	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_00396	8.47e-304	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
PHDLFKOG_00397	2.81e-209	-	-	-	K	-	-	-	sugar-binding domain protein
PHDLFKOG_00398	2.81e-167	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
PHDLFKOG_00399	2.14e-81	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PHDLFKOG_00400	1.65e-102	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_00401	1.64e-176	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PHDLFKOG_00402	5.62e-191	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PHDLFKOG_00403	1.12e-189	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PHDLFKOG_00404	7.42e-303	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	transporter
PHDLFKOG_00405	6.95e-57	-	-	-	C	-	-	-	FAD dependent oxidoreductase
PHDLFKOG_00406	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00407	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00408	5.98e-147	-	-	-	C	-	-	-	FAD dependent oxidoreductase
PHDLFKOG_00409	3.95e-138	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
PHDLFKOG_00410	2.63e-203	XK27_10120	-	-	K	-	-	-	S-adenosyl-l-methionine hydroxide adenosyltransferase
PHDLFKOG_00411	1.43e-125	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
PHDLFKOG_00412	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding cassette cobalt transporter
PHDLFKOG_00413	1.02e-188	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
PHDLFKOG_00414	6.08e-192	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
PHDLFKOG_00415	1.69e-311	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
PHDLFKOG_00416	3.54e-57	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHDLFKOG_00417	1.81e-295	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHDLFKOG_00418	0.0	frdC	1.3.5.1, 1.3.5.4	-	C	ko:K00239,ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	ko00000,ko00001,ko00002,ko01000	HI0933-like protein
PHDLFKOG_00419	1.88e-123	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
PHDLFKOG_00421	2.02e-236	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	iic component
PHDLFKOG_00422	1.47e-08	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00423	4.95e-39	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00424	1.62e-81	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
PHDLFKOG_00425	2.12e-65	-	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHDLFKOG_00426	2.26e-72	gntR	-	-	K	-	-	-	rpiR family
PHDLFKOG_00427	8e-41	ulaC	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00428	3.85e-230	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_00429	4.79e-35	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PHDLFKOG_00430	1.54e-166	-	-	-	S	-	-	-	N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
PHDLFKOG_00431	1.66e-84	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PHDLFKOG_00432	4.21e-277	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PHDLFKOG_00433	1.25e-263	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PHDLFKOG_00434	8.14e-48	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PHDLFKOG_00436	1.91e-11	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PHDLFKOG_00437	1.01e-56	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHDLFKOG_00438	3.75e-65	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PHDLFKOG_00439	1.74e-116	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
PHDLFKOG_00440	3.04e-293	bglP11	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
PHDLFKOG_00441	6.59e-291	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_00442	8.13e-294	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
PHDLFKOG_00443	4.54e-40	ptsN	2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204	-	G	ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491,ko:K11201,ko:K20112	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PHDLFKOG_00444	2.17e-215	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
PHDLFKOG_00445	9.91e-87	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00446	4.75e-58	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00447	9.7e-211	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
PHDLFKOG_00448	3.92e-159	-	-	-	G	-	-	-	Domain of unknown function (DUF4432)
PHDLFKOG_00449	5.1e-144	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
PHDLFKOG_00450	2.92e-248	xylB	2.7.1.17, 2.7.1.53	-	G	ko:K00854,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the FGGY kinase family
PHDLFKOG_00451	4.05e-258	-	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	pts system
PHDLFKOG_00452	8.16e-108	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
PHDLFKOG_00453	4.34e-217	-	3.2.1.122, 3.2.1.86	GH4,GT4	G	ko:K01222,ko:K01232	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
PHDLFKOG_00454	4.07e-24	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
PHDLFKOG_00455	2.4e-80	-	-	-	G	ko:K11201	-	ko00000,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00456	0.0	pts31BC	-	-	G	ko:K11202,ko:K11203	-	ko00000,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00457	7.61e-240	malY	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase class I and II
PHDLFKOG_00458	8.71e-271	-	-	-	G	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00459	8.9e-83	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
PHDLFKOG_00460	6.54e-58	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00461	3.78e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00462	3.51e-233	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_00463	1.67e-109	-	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
PHDLFKOG_00464	2.4e-92	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PHDLFKOG_00465	8.41e-244	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00466	1.74e-15	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
PHDLFKOG_00467	1.84e-73	-	-	-	C	-	-	-	nitroreductase
PHDLFKOG_00468	1.48e-163	-	-	-	-	-	-	-	-
PHDLFKOG_00470	4.39e-25	-	-	-	S	-	-	-	YvrJ protein family
PHDLFKOG_00471	4.01e-186	-	-	-	M	-	-	-	hydrolase, family 25
PHDLFKOG_00472	2.54e-112	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_00473	1.56e-235	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
PHDLFKOG_00474	1.22e-154	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00475	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
PHDLFKOG_00476	2.15e-193	-	-	-	S	-	-	-	hydrolase
PHDLFKOG_00477	8.23e-61	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
PHDLFKOG_00478	1.8e-209	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PHDLFKOG_00479	8.14e-98	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_00480	2.05e-165	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PHDLFKOG_00481	3.49e-185	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PHDLFKOG_00482	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PHDLFKOG_00483	5.03e-80	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PHDLFKOG_00484	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHDLFKOG_00485	1.35e-174	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PHDLFKOG_00489	2.12e-192	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PHDLFKOG_00490	9.29e-250	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
PHDLFKOG_00491	2.77e-222	-	-	-	-	-	-	-	-
PHDLFKOG_00492	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
PHDLFKOG_00493	1.61e-24	-	-	-	-	-	-	-	-
PHDLFKOG_00494	1.18e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_00495	1.22e-77	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
PHDLFKOG_00496	1.42e-133	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
PHDLFKOG_00497	2e-240	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
PHDLFKOG_00498	1.75e-100	-	-	-	O	-	-	-	OsmC-like protein
PHDLFKOG_00499	2.52e-16	-	-	-	-	-	-	-	-
PHDLFKOG_00503	0.0	-	-	-	L	-	-	-	Exonuclease
PHDLFKOG_00504	1.27e-37	-	-	-	L	-	-	-	RelB antitoxin
PHDLFKOG_00505	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00506	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00507	1.52e-39	-	-	-	-	-	-	-	-
PHDLFKOG_00508	1.04e-64	yczG	-	-	K	-	-	-	Helix-turn-helix domain
PHDLFKOG_00509	8.1e-262	yceJ	-	-	EGP	ko:K08221	-	ko00000,ko02000	transporter
PHDLFKOG_00510	2.19e-136	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PHDLFKOG_00511	4.31e-97	-	-	-	L	-	-	-	Resolvase, N-terminal
PHDLFKOG_00512	8.67e-276	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PHDLFKOG_00514	4.01e-44	-	-	-	-	-	-	-	-
PHDLFKOG_00515	7.61e-215	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
PHDLFKOG_00516	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PHDLFKOG_00517	5.86e-61	-	-	-	-	-	-	-	-
PHDLFKOG_00518	1.69e-192	pbpE	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_00519	2.26e-245	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
PHDLFKOG_00520	1.29e-177	-	-	-	H	-	-	-	Protein of unknown function (DUF1698)
PHDLFKOG_00521	3.54e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PHDLFKOG_00522	6.71e-135	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
PHDLFKOG_00523	2.96e-101	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PHDLFKOG_00524	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase N-terminal domain
PHDLFKOG_00525	5.06e-282	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
PHDLFKOG_00526	6.46e-290	-	-	-	E	-	-	-	Amino acid permease
PHDLFKOG_00527	1.82e-97	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PHDLFKOG_00528	1.52e-207	-	-	-	S	-	-	-	reductase
PHDLFKOG_00529	4.95e-246	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PHDLFKOG_00530	9.54e-78	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHDLFKOG_00531	2.64e-164	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PHDLFKOG_00532	1e-251	-	-	-	-	-	-	-	-
PHDLFKOG_00533	2.47e-166	XK27_12140	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_00534	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PHDLFKOG_00535	1.98e-163	-	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
PHDLFKOG_00536	7.75e-258	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PHDLFKOG_00537	8.79e-208	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
PHDLFKOG_00538	1.81e-252	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PHDLFKOG_00539	8.65e-136	-	-	-	-	-	-	-	-
PHDLFKOG_00540	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
PHDLFKOG_00541	0.0	ycaM	-	-	E	-	-	-	amino acid
PHDLFKOG_00542	2.09e-302	xylP	-	-	G	-	-	-	MFS/sugar transport protein
PHDLFKOG_00543	4.03e-104	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
PHDLFKOG_00544	9.58e-209	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
PHDLFKOG_00545	1.27e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
PHDLFKOG_00547	2.58e-179	-	-	-	-	-	-	-	-
PHDLFKOG_00549	1.94e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
PHDLFKOG_00550	1.61e-184	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
PHDLFKOG_00551	9.6e-156	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_00552	2.12e-173	-	-	-	-	-	-	-	-
PHDLFKOG_00553	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
PHDLFKOG_00554	3.31e-98	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PHDLFKOG_00555	1.18e-228	-	-	-	S	-	-	-	Cell surface protein
PHDLFKOG_00556	3.8e-61	-	-	-	-	-	-	-	-
PHDLFKOG_00557	6.7e-304	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PHDLFKOG_00559	3.52e-163	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PHDLFKOG_00560	2.63e-73	-	-	-	-	-	-	-	-
PHDLFKOG_00561	6.79e-152	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
PHDLFKOG_00562	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
PHDLFKOG_00563	1.21e-211	yicL	-	-	EG	-	-	-	EamA-like transporter family
PHDLFKOG_00564	0.0	-	-	-	-	-	-	-	-
PHDLFKOG_00565	7.71e-185	CcmA5	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_00566	2.58e-101	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
PHDLFKOG_00567	3.96e-187	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
PHDLFKOG_00568	5.32e-209	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
PHDLFKOG_00569	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PHDLFKOG_00570	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00571	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_00572	2.07e-281	oxlT	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
PHDLFKOG_00573	3.66e-165	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
PHDLFKOG_00574	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHDLFKOG_00575	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_00576	4.39e-273	sstT	-	-	U	ko:K07862	-	ko00000,ko02000	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PHDLFKOG_00577	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
PHDLFKOG_00578	3.78e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
PHDLFKOG_00579	2.98e-315	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
PHDLFKOG_00580	3.08e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
PHDLFKOG_00581	3.02e-92	-	-	-	-	-	-	-	-
PHDLFKOG_00582	1.95e-99	-	-	-	O	-	-	-	OsmC-like protein
PHDLFKOG_00583	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
PHDLFKOG_00584	1.11e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
PHDLFKOG_00585	1.02e-203	-	-	-	S	-	-	-	Aldo/keto reductase family
PHDLFKOG_00586	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
PHDLFKOG_00587	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
PHDLFKOG_00588	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PHDLFKOG_00589	7.8e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
PHDLFKOG_00590	1.51e-89	-	-	-	K	-	-	-	LytTr DNA-binding domain
PHDLFKOG_00591	5.16e-190	-	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PHDLFKOG_00592	7.73e-201	-	-	-	V	ko:K01990,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_00593	5.46e-187	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PHDLFKOG_00594	3.41e-144	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
PHDLFKOG_00595	1.06e-69	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
PHDLFKOG_00596	1.72e-120	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NUDIX domain
PHDLFKOG_00597	1.23e-200	-	-	-	C	-	-	-	nadph quinone reductase
PHDLFKOG_00598	1.09e-310	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
PHDLFKOG_00599	1.62e-226	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
PHDLFKOG_00600	3.15e-153	yqgG	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
PHDLFKOG_00601	2.15e-195	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
PHDLFKOG_00603	2.68e-15	-	-	-	-	-	-	-	-
PHDLFKOG_00604	2.29e-196	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PHDLFKOG_00605	1.1e-174	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
PHDLFKOG_00606	0.0	-	-	-	L	-	-	-	ATPase domain of DNA mismatch repair MUTS family
PHDLFKOG_00607	8.94e-146	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
PHDLFKOG_00608	8.08e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
PHDLFKOG_00609	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
PHDLFKOG_00610	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHDLFKOG_00611	1.76e-174	epsG	-	-	M	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_00612	5.46e-178	lacT	-	-	K	ko:K02531	-	ko00000,ko03000	PRD domain
PHDLFKOG_00613	0.0	lacE	2.7.1.207	-	G	ko:K02787,ko:K02788	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system, EIIC
PHDLFKOG_00614	4.65e-312	lacG	3.2.1.21, 3.2.1.85, 3.2.1.86	GT1	G	ko:K01220,ko:K01223,ko:K05350	ko00010,ko00052,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00052,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_00615	8.62e-66	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PHDLFKOG_00616	2.83e-283	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PHDLFKOG_00617	3.63e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
PHDLFKOG_00618	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
PHDLFKOG_00619	5.88e-213	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
PHDLFKOG_00620	5.59e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
PHDLFKOG_00622	4.46e-91	-	2.7.1.204	-	G	ko:K20112	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_00623	2.13e-64	-	2.7.1.204	-	G	ko:K20113	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_00624	0.0	gatC	-	-	G	ko:K20114	ko02060,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_00626	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00627	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00628	1.91e-38	-	-	-	-	-	-	-	-
PHDLFKOG_00629	8.15e-241	-	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_00630	3.84e-161	-	-	-	S	-	-	-	Domain of unknown function (DUF4867)
PHDLFKOG_00631	1.43e-224	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PHDLFKOG_00632	1.2e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
PHDLFKOG_00633	1.85e-121	lacB	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
PHDLFKOG_00634	6.59e-96	lacA	5.3.1.26	-	G	ko:K01819	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Ribose/Galactose Isomerase
PHDLFKOG_00635	1.01e-181	-	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
PHDLFKOG_00636	4.36e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
PHDLFKOG_00637	4.96e-270	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PHDLFKOG_00638	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
PHDLFKOG_00639	4.79e-21	-	-	-	-	-	-	-	-
PHDLFKOG_00640	5.22e-112	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
PHDLFKOG_00641	3.38e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
PHDLFKOG_00642	5.27e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PHDLFKOG_00643	1.22e-155	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
PHDLFKOG_00645	1.34e-115	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PHDLFKOG_00646	3.18e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
PHDLFKOG_00647	8.01e-254	-	-	-	-	-	-	-	-
PHDLFKOG_00649	2.6e-150	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
PHDLFKOG_00650	0.0	bglB	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	hydrolase, family 3
PHDLFKOG_00652	3.73e-214	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter substrate binding protein
PHDLFKOG_00653	3.27e-213	XK27_00670	-	-	S	ko:K01989,ko:K05832	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_00654	1.68e-208	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PHDLFKOG_00655	4.78e-180	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00656	2.27e-220	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
PHDLFKOG_00657	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
PHDLFKOG_00658	8.07e-233	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferase family 2
PHDLFKOG_00659	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
PHDLFKOG_00660	2.64e-94	-	-	-	S	-	-	-	GtrA-like protein
PHDLFKOG_00661	1.59e-14	-	-	-	-	-	-	-	-
PHDLFKOG_00662	3.17e-11	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_00663	6.13e-165	ciaR	-	-	K	ko:K14983	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
PHDLFKOG_00664	1.87e-307	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
PHDLFKOG_00665	1.99e-87	-	-	-	S	-	-	-	Belongs to the HesB IscA family
PHDLFKOG_00666	1.19e-156	ydgI	-	-	C	-	-	-	Nitroreductase family
PHDLFKOG_00667	1.69e-258	lldD	1.13.12.4	-	C	ko:K00467	ko00620,map00620	ko00000,ko00001,ko01000	IMP dehydrogenase / GMP reductase domain
PHDLFKOG_00670	1.29e-07	rggD	-	-	K	-	-	-	Transcriptional regulator RggD
PHDLFKOG_00674	7.15e-232	-	-	-	K	-	-	-	sequence-specific DNA binding
PHDLFKOG_00675	6.52e-75	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PHDLFKOG_00676	5.89e-66	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
PHDLFKOG_00677	1.71e-64	-	-	-	-	-	-	-	-
PHDLFKOG_00678	7.49e-237	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PHDLFKOG_00679	5.83e-75	-	-	-	-	-	-	-	-
PHDLFKOG_00680	6.82e-104	-	-	-	-	-	-	-	-
PHDLFKOG_00681	5.52e-265	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
PHDLFKOG_00682	1.99e-36	-	-	-	-	-	-	-	-
PHDLFKOG_00683	1e-129	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PHDLFKOG_00684	1.81e-98	-	-	-	-	-	-	-	-
PHDLFKOG_00685	3.6e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
PHDLFKOG_00686	9.06e-136	-	-	-	S	-	-	-	Flavin reductase like domain
PHDLFKOG_00687	8.46e-177	-	-	-	-	-	-	-	-
PHDLFKOG_00688	4.09e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PHDLFKOG_00689	2.41e-81	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
PHDLFKOG_00690	8.59e-221	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PHDLFKOG_00691	6.96e-206	mleR	-	-	K	-	-	-	LysR family
PHDLFKOG_00692	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
PHDLFKOG_00693	8.81e-218	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
PHDLFKOG_00694	4.58e-114	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PHDLFKOG_00695	2.95e-123	-	-	-	-	-	-	-	-
PHDLFKOG_00696	6.46e-218	-	-	-	K	-	-	-	sequence-specific DNA binding
PHDLFKOG_00697	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PHDLFKOG_00698	0.0	pepF	-	-	E	-	-	-	Oligopeptidase F
PHDLFKOG_00699	2.01e-102	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
PHDLFKOG_00700	1.05e-71	-	-	-	-	-	-	-	-
PHDLFKOG_00701	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
PHDLFKOG_00702	3.53e-227	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PHDLFKOG_00703	1.03e-77	-	-	-	-	-	-	-	-
PHDLFKOG_00704	2.66e-119	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PHDLFKOG_00705	2.39e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PHDLFKOG_00706	5.26e-155	XK27_05175	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
PHDLFKOG_00707	6.42e-101	-	-	-	K	-	-	-	Transcriptional regulator
PHDLFKOG_00708	2.81e-230	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
PHDLFKOG_00709	2.14e-110	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
PHDLFKOG_00710	1.3e-201	dkgB	-	-	S	-	-	-	reductase
PHDLFKOG_00711	1.84e-161	-	-	-	-	-	-	-	-
PHDLFKOG_00712	9.91e-205	-	-	-	S	-	-	-	Alpha beta hydrolase
PHDLFKOG_00713	4.32e-148	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
PHDLFKOG_00714	5.25e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
PHDLFKOG_00715	3.84e-280	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
PHDLFKOG_00716	1.19e-112	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PHDLFKOG_00717	1.25e-134	yjbF	-	-	S	-	-	-	SNARE associated Golgi protein
PHDLFKOG_00718	2.42e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PHDLFKOG_00719	4.98e-250	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PHDLFKOG_00720	2.16e-264	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PHDLFKOG_00721	6.98e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PHDLFKOG_00722	2.9e-85	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PHDLFKOG_00723	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
PHDLFKOG_00724	1.45e-150	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Helix-turn-helix diphteria tox regulatory element
PHDLFKOG_00725	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PHDLFKOG_00726	2.17e-265	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PHDLFKOG_00727	1.54e-305	ytoI	-	-	K	-	-	-	DRTGG domain
PHDLFKOG_00728	3.53e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PHDLFKOG_00729	0.0	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PHDLFKOG_00730	4.08e-219	-	-	-	-	-	-	-	-
PHDLFKOG_00731	1.2e-07	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHDLFKOG_00732	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PHDLFKOG_00733	9.14e-259	-	-	-	-	-	-	-	-
PHDLFKOG_00734	4.89e-58	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
PHDLFKOG_00735	3.12e-95	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PHDLFKOG_00736	1.85e-69	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
PHDLFKOG_00737	3.45e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PHDLFKOG_00738	7.74e-121	cvpA	-	-	S	-	-	-	Colicin V production protein
PHDLFKOG_00739	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PHDLFKOG_00740	3.64e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
PHDLFKOG_00741	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHDLFKOG_00742	1.46e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
PHDLFKOG_00743	1.2e-49	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PHDLFKOG_00744	5.21e-315	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PHDLFKOG_00745	1.18e-109	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
PHDLFKOG_00746	0.0	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
PHDLFKOG_00747	2.24e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
PHDLFKOG_00748	7.42e-172	gla	-	-	U	ko:K02440	-	ko00000,ko02000	Major intrinsic protein
PHDLFKOG_00749	3.12e-110	ykuL	-	-	S	-	-	-	CBS domain
PHDLFKOG_00750	1.97e-200	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
PHDLFKOG_00751	5.04e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
PHDLFKOG_00753	7.19e-40	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PHDLFKOG_00754	8.13e-104	ytxH	-	-	S	-	-	-	YtxH-like protein
PHDLFKOG_00755	1.83e-119	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
PHDLFKOG_00756	2.2e-274	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PHDLFKOG_00757	6.12e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
PHDLFKOG_00758	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin binding protein transpeptidase domain
PHDLFKOG_00759	3.18e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_00760	1.24e-162	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
PHDLFKOG_00761	2.39e-173	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PHDLFKOG_00762	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
PHDLFKOG_00763	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
PHDLFKOG_00764	3.48e-73	-	-	-	-	-	-	-	-
PHDLFKOG_00765	2.32e-238	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
PHDLFKOG_00766	2.41e-153	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
PHDLFKOG_00767	1.94e-148	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PHDLFKOG_00768	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
PHDLFKOG_00769	4.04e-142	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
PHDLFKOG_00770	4.68e-187	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PHDLFKOG_00771	8.78e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
PHDLFKOG_00772	4.31e-149	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
PHDLFKOG_00773	6.48e-115	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
PHDLFKOG_00774	9.5e-238	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
PHDLFKOG_00775	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PHDLFKOG_00776	2.02e-83	yugI	-	-	J	ko:K07570	-	ko00000	general stress protein
PHDLFKOG_00777	1.45e-46	-	-	-	-	-	-	-	-
PHDLFKOG_00778	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PHDLFKOG_00805	5.22e-120	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
PHDLFKOG_00806	0.0	ybeC	-	-	E	-	-	-	amino acid
PHDLFKOG_00807	6.32e-294	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PHDLFKOG_00808	7.35e-249	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
PHDLFKOG_00809	4.38e-222	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHDLFKOG_00810	1.24e-278	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHDLFKOG_00811	1.4e-58	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
PHDLFKOG_00812	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHDLFKOG_00813	1.8e-104	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
PHDLFKOG_00814	1.45e-46	-	-	-	-	-	-	-	-
PHDLFKOG_00815	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PHDLFKOG_00820	1.37e-270	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHDLFKOG_00821	2.16e-94	-	-	-	-	-	-	-	-
PHDLFKOG_00822	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_00823	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_00824	5.96e-131	XK27_10050	-	-	K	-	-	-	sequence-specific DNA binding
PHDLFKOG_00826	1.11e-121	-	-	-	K	-	-	-	ORF6N domain
PHDLFKOG_00831	3.67e-198	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
PHDLFKOG_00832	8.32e-51	-	-	-	S	-	-	-	ERF superfamily
PHDLFKOG_00833	1.15e-161	-	-	-	S	-	-	-	Pfam:HNHc_6
PHDLFKOG_00834	2.14e-81	-	-	-	S	-	-	-	Single-strand binding protein family
PHDLFKOG_00835	1.4e-143	-	-	-	S	-	-	-	calcium ion binding
PHDLFKOG_00836	6.62e-296	-	-	-	S	-	-	-	DNA helicase activity
PHDLFKOG_00839	7.11e-48	-	-	-	-	-	-	-	-
PHDLFKOG_00840	9.27e-86	-	-	-	S	-	-	-	magnesium ion binding
PHDLFKOG_00841	9.79e-132	-	-	-	S	-	-	-	C-5 cytosine-specific DNA methylase
PHDLFKOG_00842	9.34e-162	-	-	-	S	-	-	-	DNA methylation
PHDLFKOG_00844	7.03e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF1642)
PHDLFKOG_00845	5.89e-46	-	-	-	-	-	-	-	-
PHDLFKOG_00850	4.4e-101	-	-	-	-	-	-	-	-
PHDLFKOG_00851	4.69e-201	-	-	-	-	-	-	-	-
PHDLFKOG_00852	5.68e-280	-	-	-	S	-	-	-	GcrA cell cycle regulator
PHDLFKOG_00853	1.9e-76	-	-	-	S	-	-	-	HNH endonuclease
PHDLFKOG_00854	2.66e-60	-	-	-	-	-	-	-	-
PHDLFKOG_00856	1.02e-90	-	-	-	L	-	-	-	HNH nucleases
PHDLFKOG_00857	4.9e-100	-	-	-	S	-	-	-	Phage terminase, small subunit
PHDLFKOG_00858	0.0	-	-	-	S	-	-	-	Phage Terminase
PHDLFKOG_00860	2.08e-302	-	-	-	S	-	-	-	Phage portal protein
PHDLFKOG_00861	3.57e-144	-	-	-	S	-	-	-	peptidase activity
PHDLFKOG_00862	2.82e-262	-	-	-	S	-	-	-	peptidase activity
PHDLFKOG_00863	2.07e-20	-	-	-	S	-	-	-	peptidase activity
PHDLFKOG_00864	3.09e-36	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PHDLFKOG_00865	1.13e-51	-	-	-	S	-	-	-	Phage head-tail joining protein
PHDLFKOG_00866	7.74e-86	-	-	-	S	-	-	-	exonuclease activity
PHDLFKOG_00867	7.57e-38	-	-	-	-	-	-	-	-
PHDLFKOG_00868	2.29e-92	-	-	-	S	-	-	-	Pfam:Phage_TTP_1
PHDLFKOG_00869	2.72e-27	-	-	-	-	-	-	-	-
PHDLFKOG_00870	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
PHDLFKOG_00871	9.24e-305	-	-	-	S	-	-	-	Phage tail protein
PHDLFKOG_00872	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
PHDLFKOG_00873	5.89e-63	-	-	-	-	-	-	-	-
PHDLFKOG_00875	7.87e-69	-	-	-	-	-	-	-	-
PHDLFKOG_00876	1.24e-65	hol	-	-	S	-	-	-	Bacteriophage holin
PHDLFKOG_00877	1.22e-231	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PHDLFKOG_00879	1e-138	-	-	-	-	-	-	-	-
PHDLFKOG_00880	1.66e-269	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PHDLFKOG_00881	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_00882	3.41e-107	-	-	-	K	-	-	-	MerR HTH family regulatory protein
PHDLFKOG_00883	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PHDLFKOG_00884	7.22e-153	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PHDLFKOG_00885	2.47e-154	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
PHDLFKOG_00886	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
PHDLFKOG_00887	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PHDLFKOG_00888	6.61e-167	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PHDLFKOG_00889	8.09e-48	yhcC	-	-	S	ko:K07069	-	ko00000	Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
PHDLFKOG_00890	2.06e-174	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PHDLFKOG_00891	9.29e-123	-	-	-	F	-	-	-	NUDIX domain
PHDLFKOG_00893	3.41e-112	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
PHDLFKOG_00894	1.49e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
PHDLFKOG_00895	5.43e-281	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PHDLFKOG_00896	1.19e-50	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
PHDLFKOG_00897	3.14e-310	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
PHDLFKOG_00898	1.12e-270	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
PHDLFKOG_00899	8.12e-151	yjbH	-	-	Q	-	-	-	Thioredoxin
PHDLFKOG_00900	8.17e-135	-	-	-	S	-	-	-	CYTH
PHDLFKOG_00901	4.15e-160	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
PHDLFKOG_00902	2.24e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PHDLFKOG_00903	5.18e-221	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PHDLFKOG_00904	3.99e-258	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHDLFKOG_00905	1.51e-144	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
PHDLFKOG_00906	1.61e-185	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PHDLFKOG_00907	3.13e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
PHDLFKOG_00908	7.55e-82	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PHDLFKOG_00909	4.12e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHDLFKOG_00910	9.97e-245	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PHDLFKOG_00911	9.63e-220	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
PHDLFKOG_00912	9.45e-198	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
PHDLFKOG_00913	6.48e-125	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PHDLFKOG_00914	8.84e-93	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
PHDLFKOG_00915	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PHDLFKOG_00916	7.4e-293	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
PHDLFKOG_00917	3.94e-309	ymfH	-	-	S	-	-	-	Peptidase M16
PHDLFKOG_00918	1.43e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PHDLFKOG_00919	1.8e-167	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
PHDLFKOG_00920	7.88e-135	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PHDLFKOG_00921	3.23e-288	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
PHDLFKOG_00922	6.68e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHDLFKOG_00923	2.37e-29	-	-	-	-	-	-	-	-
PHDLFKOG_00924	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
PHDLFKOG_00925	2.6e-150	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
PHDLFKOG_00926	3.04e-297	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
PHDLFKOG_00927	1.8e-117	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
PHDLFKOG_00928	7.96e-127	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PHDLFKOG_00929	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHDLFKOG_00930	6.43e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PHDLFKOG_00931	2.59e-160	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	ABC transporter
PHDLFKOG_00932	4.17e-204	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PHDLFKOG_00933	7.95e-251	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
PHDLFKOG_00934	9.79e-168	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PHDLFKOG_00935	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHDLFKOG_00936	5.25e-199	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PHDLFKOG_00937	1.56e-205	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
PHDLFKOG_00938	3.55e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
PHDLFKOG_00939	1.83e-191	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHDLFKOG_00940	1.75e-180	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PHDLFKOG_00941	1.33e-156	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
PHDLFKOG_00942	0.0	yvlB	-	-	S	-	-	-	Putative adhesin
PHDLFKOG_00943	7.01e-49	-	-	-	-	-	-	-	-
PHDLFKOG_00944	2.28e-61	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
PHDLFKOG_00945	5.82e-223	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PHDLFKOG_00946	2e-201	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PHDLFKOG_00947	1.8e-249	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
PHDLFKOG_00948	8.36e-230	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PHDLFKOG_00949	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PHDLFKOG_00950	2.18e-109	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PHDLFKOG_00951	3.28e-143	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
PHDLFKOG_00952	1.21e-117	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_00953	6.82e-104	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PHDLFKOG_00954	2.3e-178	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PHDLFKOG_00955	2.32e-152	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
PHDLFKOG_00956	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PHDLFKOG_00957	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PHDLFKOG_00958	2.98e-110	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
PHDLFKOG_00959	1.47e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
PHDLFKOG_00960	8.22e-246	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
PHDLFKOG_00961	3.36e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
PHDLFKOG_00962	6.45e-105	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
PHDLFKOG_00963	1.71e-131	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PHDLFKOG_00965	2.73e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
PHDLFKOG_00966	2.99e-247	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PHDLFKOG_00967	1.52e-282	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
PHDLFKOG_00968	8.05e-180	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PHDLFKOG_00969	5.04e-314	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PHDLFKOG_00970	5.53e-84	-	-	-	-	-	-	-	-
PHDLFKOG_00971	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
PHDLFKOG_00972	1.48e-78	-	-	-	-	-	-	-	-
PHDLFKOG_00973	2.92e-42	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
PHDLFKOG_00974	3.69e-177	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
PHDLFKOG_00975	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PHDLFKOG_00976	9.03e-108	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PHDLFKOG_00977	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PHDLFKOG_00978	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
PHDLFKOG_00979	3.38e-149	-	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
PHDLFKOG_00980	7.78e-66	-	-	-	-	-	-	-	-
PHDLFKOG_00982	6.97e-304	YSH1	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Metallo-beta-lactamase superfamily
PHDLFKOG_00983	5.23e-313	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PHDLFKOG_00984	1.1e-188	malF	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PHDLFKOG_00985	1.21e-213	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
PHDLFKOG_00986	2.11e-249	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_00987	7.94e-134	-	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
PHDLFKOG_00988	5.33e-119	-	-	-	-	-	-	-	-
PHDLFKOG_00989	1.98e-203	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PHDLFKOG_00990	4.68e-168	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PHDLFKOG_00991	6.35e-230	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
PHDLFKOG_00992	1.2e-106	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
PHDLFKOG_00993	2.96e-210	-	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_00994	2.05e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PHDLFKOG_00995	1.62e-128	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PHDLFKOG_00996	3.32e-191	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
PHDLFKOG_00997	2.74e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
PHDLFKOG_00998	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
PHDLFKOG_00999	4.84e-125	-	-	-	K	-	-	-	Cupin domain
PHDLFKOG_01000	9.49e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PHDLFKOG_01001	2.13e-191	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01002	7.08e-187	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01003	2.08e-267	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_01004	2.03e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF5067)
PHDLFKOG_01005	2.37e-79	-	-	-	-	-	-	-	-
PHDLFKOG_01007	0.0	pacL	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
PHDLFKOG_01008	7.67e-152	-	-	-	K	-	-	-	Transcriptional regulator
PHDLFKOG_01009	1.16e-234	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_01010	1.12e-162	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PHDLFKOG_01011	2.69e-195	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PHDLFKOG_01012	2.39e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
PHDLFKOG_01013	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PHDLFKOG_01014	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PHDLFKOG_01015	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
PHDLFKOG_01016	1.8e-119	-	-	-	S	-	-	-	VanZ like family
PHDLFKOG_01017	1.75e-170	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
PHDLFKOG_01018	5.7e-183	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
PHDLFKOG_01019	1.91e-211	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
PHDLFKOG_01020	2e-64	-	-	-	-	ko:K02245	-	ko00000,ko00002,ko02044	-
PHDLFKOG_01022	3.45e-63	-	-	-	-	-	-	-	-
PHDLFKOG_01023	2.14e-105	-	-	-	-	ko:K02248	-	ko00000,ko00002,ko02044	-
PHDLFKOG_01024	1.84e-65	-	-	-	-	-	-	-	-
PHDLFKOG_01025	3.7e-235	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
PHDLFKOG_01026	1.58e-96	-	-	-	-	-	-	-	-
PHDLFKOG_01027	1.03e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
PHDLFKOG_01028	1.34e-184	arbV	-	-	I	-	-	-	Phosphate acyltransferases
PHDLFKOG_01029	1.36e-210	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
PHDLFKOG_01030	6.11e-229	arbY	-	-	M	-	-	-	family 8
PHDLFKOG_01031	2.93e-207	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
PHDLFKOG_01032	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PHDLFKOG_01033	4.11e-273	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHDLFKOG_01034	2.32e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
PHDLFKOG_01035	1.85e-58	-	-	-	-	-	-	-	-
PHDLFKOG_01036	8.37e-42	-	-	-	-	-	-	-	-
PHDLFKOG_01037	1.6e-21	-	-	-	-	-	-	-	-
PHDLFKOG_01038	1.85e-36	-	-	-	-	-	-	-	-
PHDLFKOG_01039	2.89e-43	-	-	-	-	-	-	-	-
PHDLFKOG_01040	1.18e-34	-	-	-	-	-	-	-	-
PHDLFKOG_01041	5.43e-190	-	-	-	L	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
PHDLFKOG_01042	2.9e-174	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
PHDLFKOG_01044	9.4e-105	terS	-	-	L	-	-	-	Phage terminase, small subunit
PHDLFKOG_01045	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
PHDLFKOG_01046	6.06e-29	-	-	-	-	-	-	-	-
PHDLFKOG_01047	5.66e-277	-	-	-	S	-	-	-	Phage portal protein
PHDLFKOG_01048	0.0	-	-	-	S	ko:K06904	-	ko00000	Phage capsid family
PHDLFKOG_01049	1.88e-62	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
PHDLFKOG_01050	3.8e-17	-	-	-	S	-	-	-	Phage head-tail joining protein
PHDLFKOG_01051	2.3e-23	-	-	-	-	-	-	-	-
PHDLFKOG_01052	1.4e-35	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
PHDLFKOG_01053	1.26e-52	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHDLFKOG_01055	1.55e-91	-	-	-	S	-	-	-	SdpI/YhfL protein family
PHDLFKOG_01056	3.15e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PHDLFKOG_01057	0.0	yclK	-	-	T	-	-	-	Histidine kinase
PHDLFKOG_01058	1.9e-121	-	-	-	S	-	-	-	acetyltransferase
PHDLFKOG_01059	2.21e-42	-	-	-	-	-	-	-	-
PHDLFKOG_01060	1.49e-93	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
PHDLFKOG_01061	2.24e-106	-	-	-	-	-	-	-	-
PHDLFKOG_01062	1.41e-77	-	-	-	-	-	-	-	-
PHDLFKOG_01063	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
PHDLFKOG_01065	4.45e-173	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PHDLFKOG_01066	2.4e-163	-	3.1.1.5	-	E	ko:K10804	ko01040,map01040	ko00000,ko00001,ko01000,ko01004	GDSL-like Lipase/Acylhydrolase
PHDLFKOG_01067	1.3e-51	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF898)
PHDLFKOG_01068	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
PHDLFKOG_01069	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PHDLFKOG_01070	2.36e-260	camS	-	-	S	-	-	-	sex pheromone
PHDLFKOG_01071	1.26e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHDLFKOG_01072	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PHDLFKOG_01073	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PHDLFKOG_01074	1.42e-247	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
PHDLFKOG_01075	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHDLFKOG_01076	8.36e-277	yttB	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_01077	8.04e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PHDLFKOG_01078	2.97e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
PHDLFKOG_01079	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PHDLFKOG_01080	7.53e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01081	7.88e-211	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PHDLFKOG_01082	1.95e-166	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
PHDLFKOG_01083	1.05e-40	-	-	-	-	-	-	-	-
PHDLFKOG_01084	1.28e-171	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
PHDLFKOG_01085	3.83e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PHDLFKOG_01086	3.98e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
PHDLFKOG_01087	1.14e-228	mocA	-	-	S	-	-	-	Oxidoreductase
PHDLFKOG_01088	5.1e-301	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
PHDLFKOG_01089	2.05e-63	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PHDLFKOG_01090	1.1e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PHDLFKOG_01092	5.65e-07	-	-	-	-	-	-	-	-
PHDLFKOG_01093	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PHDLFKOG_01094	1.35e-304	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	Thermophilic metalloprotease (M29)
PHDLFKOG_01095	1.41e-142	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_01097	6.23e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_01098	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
PHDLFKOG_01099	1.82e-229	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
PHDLFKOG_01100	3.05e-104	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
PHDLFKOG_01101	2.34e-204	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
PHDLFKOG_01102	9.28e-248	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_01104	2.12e-40	-	-	-	-	-	-	-	-
PHDLFKOG_01105	6.33e-253	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
PHDLFKOG_01106	1.53e-216	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
PHDLFKOG_01107	2.19e-149	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
PHDLFKOG_01109	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01110	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01112	1.06e-39	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
PHDLFKOG_01113	1.09e-270	secA2	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PHDLFKOG_01114	1.59e-70	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_01115	7.09e-278	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_01116	0.0	bglH	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_01117	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
PHDLFKOG_01118	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PHDLFKOG_01119	3.76e-107	-	-	-	S	-	-	-	Fic/DOC family
PHDLFKOG_01120	4.96e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
PHDLFKOG_01121	5.01e-142	-	-	-	-	-	-	-	-
PHDLFKOG_01122	2.84e-215	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
PHDLFKOG_01123	6.22e-43	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PHDLFKOG_01124	1.73e-35	-	-	-	T	-	-	-	PFAM SpoVT AbrB
PHDLFKOG_01125	2.8e-105	yvbK	-	-	K	-	-	-	GNAT family
PHDLFKOG_01126	1.84e-147	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
PHDLFKOG_01127	7.6e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PHDLFKOG_01128	1.87e-304	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
PHDLFKOG_01129	2.43e-263	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHDLFKOG_01130	1.74e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PHDLFKOG_01132	1.8e-134	-	-	-	-	-	-	-	-
PHDLFKOG_01133	1.37e-165	-	-	-	-	-	-	-	-
PHDLFKOG_01134	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PHDLFKOG_01135	3.74e-142	vanZ	-	-	V	-	-	-	VanZ like family
PHDLFKOG_01136	5.43e-195	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
PHDLFKOG_01137	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
PHDLFKOG_01139	7.12e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PHDLFKOG_01140	7.26e-183	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
PHDLFKOG_01141	7.92e-102	-	-	-	S	-	-	-	Pfam Transposase IS66
PHDLFKOG_01142	2.18e-291	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	Glycosyl transferases group 1
PHDLFKOG_01143	3.12e-220	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
PHDLFKOG_01144	4e-110	guaD	-	-	FJ	-	-	-	MafB19-like deaminase
PHDLFKOG_01152	1.56e-25	-	-	-	-	-	-	-	-
PHDLFKOG_01153	8e-247	yttB	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_01154	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHDLFKOG_01159	3.56e-168	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
PHDLFKOG_01160	5.26e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_01161	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01162	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PHDLFKOG_01163	4.13e-178	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
PHDLFKOG_01164	9.19e-209	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
PHDLFKOG_01165	2.09e-244	ampC	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_01166	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
PHDLFKOG_01167	8.22e-144	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
PHDLFKOG_01168	3.51e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PHDLFKOG_01169	1.63e-196	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PHDLFKOG_01170	7.03e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PHDLFKOG_01171	1.29e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PHDLFKOG_01172	8.75e-145	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PHDLFKOG_01173	4.11e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
PHDLFKOG_01174	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHDLFKOG_01175	8.51e-72	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PHDLFKOG_01176	4.59e-115	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PHDLFKOG_01177	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PHDLFKOG_01178	1.78e-211	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PHDLFKOG_01180	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PHDLFKOG_01181	6.51e-83	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
PHDLFKOG_01182	5.78e-19	-	-	-	-	-	-	-	-
PHDLFKOG_01183	2.5e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
PHDLFKOG_01184	2.13e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
PHDLFKOG_01185	5.48e-35	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
PHDLFKOG_01186	1.62e-72	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
PHDLFKOG_01187	2.92e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
PHDLFKOG_01188	1.35e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
PHDLFKOG_01189	1.41e-63	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
PHDLFKOG_01190	2.56e-272	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PHDLFKOG_01191	1.56e-189	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PHDLFKOG_01192	8.69e-192	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
PHDLFKOG_01193	9.88e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PHDLFKOG_01194	5.58e-151	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01195	2.4e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
PHDLFKOG_01196	1.21e-243	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
PHDLFKOG_01197	1.39e-281	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PHDLFKOG_01198	1.42e-102	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
PHDLFKOG_01199	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
PHDLFKOG_01201	2.14e-36	-	-	-	-	-	-	-	-
PHDLFKOG_01202	8.1e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PHDLFKOG_01203	3.54e-230	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
PHDLFKOG_01204	2.16e-206	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHDLFKOG_01205	6.47e-110	uspA	-	-	T	-	-	-	universal stress protein
PHDLFKOG_01206	1.41e-53	-	-	-	-	-	-	-	-
PHDLFKOG_01207	1.84e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
PHDLFKOG_01208	0.0	-	6.3.2.2	-	M	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Mur ligase middle domain protein
PHDLFKOG_01209	1.63e-95	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
PHDLFKOG_01210	4.72e-141	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
PHDLFKOG_01211	2.93e-158	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
PHDLFKOG_01212	1.01e-192	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PHDLFKOG_01213	2.9e-158	-	-	-	G	-	-	-	Phosphoglycerate mutase family
PHDLFKOG_01214	1.4e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHDLFKOG_01215	5.95e-212	-	-	-	IQ	-	-	-	NAD dependent epimerase/dehydratase family
PHDLFKOG_01216	1.02e-178	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
PHDLFKOG_01217	3.98e-171	-	-	-	F	-	-	-	deoxynucleoside kinase
PHDLFKOG_01218	9.53e-202	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphatase and related hydrolases of the PHP family
PHDLFKOG_01219	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PHDLFKOG_01220	1.15e-204	-	-	-	T	-	-	-	GHKL domain
PHDLFKOG_01221	1.38e-153	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PHDLFKOG_01222	4.56e-215	bcrA	-	-	V	ko:K01990,ko:K19309	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
PHDLFKOG_01223	2.07e-164	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PHDLFKOG_01224	1.2e-207	-	-	-	K	-	-	-	Transcriptional regulator
PHDLFKOG_01225	2.71e-102	yphH	-	-	S	-	-	-	Cupin domain
PHDLFKOG_01226	2.24e-72	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PHDLFKOG_01227	4.39e-06	-	-	-	-	-	-	-	-
PHDLFKOG_01228	1.14e-107	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PHDLFKOG_01229	1.72e-208	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01230	4.66e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01231	8.05e-197	degV	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
PHDLFKOG_01232	1.04e-135	-	-	-	-	-	-	-	-
PHDLFKOG_01233	2.93e-133	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
PHDLFKOG_01234	1.62e-256	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHDLFKOG_01235	6.21e-165	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
PHDLFKOG_01236	1.83e-202	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_01237	0.0	-	-	-	-	-	-	-	-
PHDLFKOG_01238	4.64e-188	-	-	-	-	-	-	-	-
PHDLFKOG_01239	3.68e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01240	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
PHDLFKOG_01241	2.4e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
PHDLFKOG_01242	1.13e-289	-	-	-	E	-	-	-	Amino acid permease
PHDLFKOG_01243	2.14e-164	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
PHDLFKOG_01244	2.45e-175	-	-	-	S	-	-	-	Domain of unknown function (DUF1998)
PHDLFKOG_01245	0.0	-	-	-	KL	-	-	-	Helicase conserved C-terminal domain
PHDLFKOG_01247	5.31e-143	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PHDLFKOG_01248	6.83e-109	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
PHDLFKOG_01249	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PHDLFKOG_01250	3.81e-275	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PHDLFKOG_01251	1.73e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PHDLFKOG_01252	3.97e-149	-	-	-	K	ko:K01926	-	ko00000,ko03000	CoA binding domain
PHDLFKOG_01253	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PHDLFKOG_01254	5.13e-304	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
PHDLFKOG_01255	1.63e-147	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
PHDLFKOG_01256	2.01e-151	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
PHDLFKOG_01257	6.84e-229	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
PHDLFKOG_01258	5.62e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
PHDLFKOG_01259	2.13e-113	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
PHDLFKOG_01260	1.28e-146	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PHDLFKOG_01261	6.07e-182	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
PHDLFKOG_01262	2.77e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01263	1.29e-143	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
PHDLFKOG_01264	1.63e-193	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
PHDLFKOG_01266	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHDLFKOG_01267	4.32e-14	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
PHDLFKOG_01268	1.49e-70	-	-	-	-	-	-	-	-
PHDLFKOG_01269	1.61e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
PHDLFKOG_01270	4.57e-217	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PHDLFKOG_01271	8.26e-80	ftsL	-	-	D	-	-	-	cell division protein FtsL
PHDLFKOG_01272	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PHDLFKOG_01273	3.67e-227	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PHDLFKOG_01274	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PHDLFKOG_01275	3.84e-257	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PHDLFKOG_01276	4.67e-196	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PHDLFKOG_01277	6.05e-307	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PHDLFKOG_01278	2.19e-290	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PHDLFKOG_01279	5.1e-102	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PHDLFKOG_01280	6.86e-60	yggT	-	-	D	ko:K02221	-	ko00000,ko02044	integral membrane protein
PHDLFKOG_01281	1.91e-185	ylmH	-	-	S	-	-	-	S4 domain protein
PHDLFKOG_01282	2.93e-109	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA protein
PHDLFKOG_01283	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PHDLFKOG_01284	2.98e-49	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
PHDLFKOG_01285	6.09e-200	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
PHDLFKOG_01286	0.0	ydiC1	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_01287	8.52e-268	yaaN	-	-	P	-	-	-	Toxic anion resistance protein (TelA)
PHDLFKOG_01288	9.37e-150	-	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
PHDLFKOG_01289	1.56e-127	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
PHDLFKOG_01290	1.36e-46	-	-	-	-	-	-	-	-
PHDLFKOG_01291	3.94e-159	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PHDLFKOG_01292	9.79e-279	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
PHDLFKOG_01293	3.61e-77	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
PHDLFKOG_01294	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
PHDLFKOG_01295	8.38e-278	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PHDLFKOG_01296	9.46e-159	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
PHDLFKOG_01297	8.3e-150	-	-	-	S	-	-	-	repeat protein
PHDLFKOG_01298	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PHDLFKOG_01299	2.35e-311	-	-	-	S	-	-	-	Sterol carrier protein domain
PHDLFKOG_01300	5.92e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PHDLFKOG_01301	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHDLFKOG_01302	4.07e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
PHDLFKOG_01304	2.95e-96	-	-	-	-	-	-	-	-
PHDLFKOG_01305	1.83e-35	-	-	-	-	-	-	-	-
PHDLFKOG_01306	1.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PHDLFKOG_01307	8.12e-174	-	-	-	S	-	-	-	E1-E2 ATPase
PHDLFKOG_01308	1.65e-266	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
PHDLFKOG_01309	1.34e-231	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
PHDLFKOG_01310	6.23e-314	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PHDLFKOG_01311	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
PHDLFKOG_01312	7.16e-201	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
PHDLFKOG_01313	8.74e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
PHDLFKOG_01314	1.06e-186	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
PHDLFKOG_01315	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
PHDLFKOG_01316	3.76e-268	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
PHDLFKOG_01317	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PHDLFKOG_01318	2.84e-75	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
PHDLFKOG_01319	2.89e-129	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
PHDLFKOG_01320	2.96e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PHDLFKOG_01321	2.04e-247	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
PHDLFKOG_01322	1.96e-147	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
PHDLFKOG_01323	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
PHDLFKOG_01324	7.05e-248	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
PHDLFKOG_01325	5.85e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
PHDLFKOG_01326	2.48e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PHDLFKOG_01327	6.79e-152	-	-	-	-	-	-	-	-
PHDLFKOG_01328	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PHDLFKOG_01329	1.98e-205	-	-	-	S	-	-	-	Tetratricopeptide repeat
PHDLFKOG_01330	4.73e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PHDLFKOG_01331	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01332	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01333	1.14e-108	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
PHDLFKOG_01334	1.24e-172	-	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
PHDLFKOG_01335	1.12e-83	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
PHDLFKOG_01336	2.93e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PHDLFKOG_01337	0.0	yknV	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
PHDLFKOG_01338	8.34e-271	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PHDLFKOG_01339	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PHDLFKOG_01340	5.12e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
PHDLFKOG_01341	2.28e-63	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
PHDLFKOG_01342	2.34e-28	-	-	-	-	-	-	-	-
PHDLFKOG_01343	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01344	1.33e-172	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01345	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PHDLFKOG_01346	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
PHDLFKOG_01347	1.21e-212	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHDLFKOG_01348	5.84e-172	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
PHDLFKOG_01349	1.29e-297	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PHDLFKOG_01350	0.0	oatA	-	-	I	-	-	-	Acyltransferase
PHDLFKOG_01351	2.92e-232	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PHDLFKOG_01352	1.28e-181	yqjQ	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
PHDLFKOG_01353	5.47e-63	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
PHDLFKOG_01354	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHDLFKOG_01355	1.35e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
PHDLFKOG_01356	3.37e-123	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
PHDLFKOG_01357	0.0	ycjM	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
PHDLFKOG_01358	2.15e-187	-	-	-	-	-	-	-	-
PHDLFKOG_01359	2.92e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
PHDLFKOG_01360	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
PHDLFKOG_01361	9e-227	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PHDLFKOG_01362	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
PHDLFKOG_01363	7.15e-94	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
PHDLFKOG_01364	7.26e-209	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
PHDLFKOG_01365	2.09e-212	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
PHDLFKOG_01366	2.81e-88	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PHDLFKOG_01367	8.93e-163	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PHDLFKOG_01368	6.34e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PHDLFKOG_01369	3.03e-178	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
PHDLFKOG_01370	4.54e-125	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PHDLFKOG_01371	4.03e-61	fer	-	-	C	ko:K05337	-	ko00000	4Fe-4S single cluster domain of Ferredoxin I
PHDLFKOG_01372	1.83e-231	-	-	-	S	-	-	-	Helix-turn-helix domain
PHDLFKOG_01373	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
PHDLFKOG_01374	6.23e-87	-	-	-	M	-	-	-	Lysin motif
PHDLFKOG_01375	1.09e-149	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
PHDLFKOG_01376	6.19e-300	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
PHDLFKOG_01377	3.67e-312	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
PHDLFKOG_01378	1.6e-54	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PHDLFKOG_01379	3.7e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
PHDLFKOG_01380	2.95e-207	ypjC	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHDLFKOG_01381	1.12e-285	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PHDLFKOG_01382	2.08e-110	-	-	-	-	-	-	-	-
PHDLFKOG_01383	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01384	1.03e-244	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PHDLFKOG_01385	1.48e-118	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PHDLFKOG_01386	9.09e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
PHDLFKOG_01387	2.79e-190	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
PHDLFKOG_01388	3.87e-202	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
PHDLFKOG_01389	5.89e-145	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
PHDLFKOG_01390	5.75e-112	msrA	1.8.4.11	-	C	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PHDLFKOG_01391	2.52e-55	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
PHDLFKOG_01392	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
PHDLFKOG_01393	6.14e-75	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PHDLFKOG_01394	6.44e-12	-	-	-	-	-	-	-	-
PHDLFKOG_01395	3.27e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF4918)
PHDLFKOG_01396	7.5e-202	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PHDLFKOG_01397	1.61e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHDLFKOG_01398	4.65e-189	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
PHDLFKOG_01399	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PHDLFKOG_01400	3.4e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PHDLFKOG_01401	3.34e-214	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
PHDLFKOG_01402	8.41e-119	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PHDLFKOG_01403	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PHDLFKOG_01404	4.61e-220	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
PHDLFKOG_01405	5.92e-142	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PHDLFKOG_01406	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHDLFKOG_01407	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PHDLFKOG_01408	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
PHDLFKOG_01409	3.64e-217	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHDLFKOG_01410	1.15e-235	-	-	-	K	-	-	-	LysR substrate binding domain
PHDLFKOG_01411	1.13e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
PHDLFKOG_01412	1.93e-265	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
PHDLFKOG_01413	0.0	XK27_05700	-	-	V	ko:K02004,ko:K19084	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	FtsX-like permease family
PHDLFKOG_01414	5.18e-174	XK27_05695	-	-	V	ko:K02003,ko:K19083	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01415	5.58e-221	-	-	-	T	-	-	-	Histidine kinase-like ATPases
PHDLFKOG_01416	1.24e-164	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
PHDLFKOG_01417	2.13e-277	-	-	-	EGP	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
PHDLFKOG_01418	7.37e-90	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01419	1.22e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01420	1.76e-145	-	-	-	C	-	-	-	Nitroreductase family
PHDLFKOG_01421	3.82e-187	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
PHDLFKOG_01422	4.53e-263	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PHDLFKOG_01423	5.01e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
PHDLFKOG_01424	4.81e-76	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PHDLFKOG_01425	4.26e-171	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PHDLFKOG_01426	1.38e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PHDLFKOG_01427	1.15e-144	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PHDLFKOG_01428	9.96e-135	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
PHDLFKOG_01429	3.62e-287	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PHDLFKOG_01430	1.34e-139	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PHDLFKOG_01431	1.1e-277	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PHDLFKOG_01432	1.99e-260	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Cys/Met metabolism PLP-dependent enzyme
PHDLFKOG_01433	3.8e-130	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
PHDLFKOG_01434	3.08e-207	-	-	-	S	-	-	-	EDD domain protein, DegV family
PHDLFKOG_01436	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
PHDLFKOG_01437	1.43e-67	-	-	-	S	-	-	-	MazG-like family
PHDLFKOG_01438	3.31e-246	pfoS/R	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PHDLFKOG_01439	3.69e-143	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PHDLFKOG_01440	1.55e-162	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PHDLFKOG_01441	3.8e-193	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PHDLFKOG_01442	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
PHDLFKOG_01443	5.32e-267	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
PHDLFKOG_01444	1.12e-305	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PHDLFKOG_01445	5.88e-229	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
PHDLFKOG_01446	2.33e-299	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
PHDLFKOG_01447	3.67e-126	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PHDLFKOG_01448	1.74e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PHDLFKOG_01449	1.99e-106	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PHDLFKOG_01450	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
PHDLFKOG_01451	5.76e-84	-	-	-	S	-	-	-	Family of unknown function (DUF5322)
PHDLFKOG_01452	5.59e-90	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
PHDLFKOG_01453	2.85e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
PHDLFKOG_01454	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PHDLFKOG_01455	5.46e-72	-	-	-	-	-	-	-	-
PHDLFKOG_01456	4.86e-05	-	-	-	-	-	-	-	-
PHDLFKOG_01457	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_01458	1.76e-51	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
PHDLFKOG_01459	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHDLFKOG_01460	2.95e-240	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PHDLFKOG_01462	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01463	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01464	1.2e-167	lysR	-	-	K	-	-	-	Transcriptional regulator
PHDLFKOG_01465	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
PHDLFKOG_01466	4.08e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
PHDLFKOG_01467	7.29e-46	-	-	-	-	-	-	-	-
PHDLFKOG_01468	2.57e-222	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PHDLFKOG_01469	5.02e-277	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
PHDLFKOG_01471	5.37e-88	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PHDLFKOG_01472	1.54e-136	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
PHDLFKOG_01473	4.21e-156	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PHDLFKOG_01474	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
PHDLFKOG_01475	7.79e-112	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
PHDLFKOG_01476	1.9e-147	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PHDLFKOG_01477	9.49e-143	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
PHDLFKOG_01478	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
PHDLFKOG_01479	3.43e-281	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
PHDLFKOG_01480	8.92e-111	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
PHDLFKOG_01481	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
PHDLFKOG_01482	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
PHDLFKOG_01483	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PHDLFKOG_01484	4.19e-212	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
PHDLFKOG_01485	3.66e-229	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
PHDLFKOG_01486	7.36e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PHDLFKOG_01487	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
PHDLFKOG_01488	1.54e-222	-	-	-	-	-	-	-	-
PHDLFKOG_01489	5.06e-181	-	-	-	-	-	-	-	-
PHDLFKOG_01490	1.15e-79	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
PHDLFKOG_01491	1.05e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
PHDLFKOG_01492	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	(ABC) transporter
PHDLFKOG_01493	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PHDLFKOG_01494	5.24e-187	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PHDLFKOG_01495	6.34e-165	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
PHDLFKOG_01496	1.21e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PHDLFKOG_01497	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PHDLFKOG_01498	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
PHDLFKOG_01499	1.96e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
PHDLFKOG_01500	1.15e-121	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PHDLFKOG_01501	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01502	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01504	1.08e-155	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_01505	7.35e-70	-	-	-	-	-	-	-	-
PHDLFKOG_01506	4.96e-188	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
PHDLFKOG_01507	5.57e-216	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PHDLFKOG_01508	8.35e-84	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PHDLFKOG_01509	4.25e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
PHDLFKOG_01510	5.09e-107	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PHDLFKOG_01511	6.59e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
PHDLFKOG_01512	1.47e-90	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
PHDLFKOG_01513	5.66e-29	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
PHDLFKOG_01514	4.18e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PHDLFKOG_01515	6.26e-215	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PHDLFKOG_01516	7.61e-217	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHDLFKOG_01517	1.26e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
PHDLFKOG_01518	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PHDLFKOG_01519	1.8e-308	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
PHDLFKOG_01520	0.0	-	-	-	-	-	-	-	-
PHDLFKOG_01521	1.95e-168	-	-	-	V	-	-	-	ABC transporter
PHDLFKOG_01522	1.72e-103	-	-	-	FG	-	-	-	adenosine 5'-monophosphoramidase activity
PHDLFKOG_01523	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
PHDLFKOG_01524	2.95e-147	-	-	-	J	-	-	-	HAD-hyrolase-like
PHDLFKOG_01525	2.17e-97	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PHDLFKOG_01526	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_01527	1.7e-70	-	-	-	-	-	-	-	-
PHDLFKOG_01528	7.38e-167	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PHDLFKOG_01529	5.37e-221	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
PHDLFKOG_01530	2.02e-112	XK27_03960	-	-	S	-	-	-	Protein of unknown function (DUF3013)
PHDLFKOG_01531	2.26e-143	-	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
PHDLFKOG_01532	1.1e-50	-	-	-	-	-	-	-	-
PHDLFKOG_01533	9.77e-80	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PHDLFKOG_01534	3.45e-37	-	-	-	-	-	-	-	-
PHDLFKOG_01535	1.05e-79	-	-	-	-	-	-	-	-
PHDLFKOG_01537	1.6e-145	-	-	-	S	-	-	-	Flavodoxin-like fold
PHDLFKOG_01538	3.21e-117	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_01539	5.29e-238	mocA	-	-	S	-	-	-	Oxidoreductase
PHDLFKOG_01540	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHDLFKOG_01541	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PHDLFKOG_01543	0.0	-	2.4.1.9, 3.4.24.40	GH68	M	ko:K01406,ko:K20811	ko00500,ko01503,map00500,map01503	ko00000,ko00001,ko01000,ko01002	domain protein
PHDLFKOG_01545	0.0	-	-	-	-	-	-	-	-
PHDLFKOG_01546	1.98e-267	-	-	-	-	-	-	-	-
PHDLFKOG_01547	1.07e-238	-	-	-	-	-	-	-	-
PHDLFKOG_01548	5.46e-189	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	N-formylglutamate amidohydrolase
PHDLFKOG_01549	8.85e-72	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
PHDLFKOG_01550	2.18e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PHDLFKOG_01551	4.87e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PHDLFKOG_01552	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
PHDLFKOG_01553	2.01e-81	-	-	-	-	-	-	-	-
PHDLFKOG_01554	4.13e-109	-	-	-	S	-	-	-	ASCH
PHDLFKOG_01555	4.01e-44	-	-	-	-	-	-	-	-
PHDLFKOG_01556	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PHDLFKOG_01557	6.01e-268	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PHDLFKOG_01558	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
PHDLFKOG_01559	2.41e-127	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PHDLFKOG_01560	2.27e-246	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PHDLFKOG_01561	2.08e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
PHDLFKOG_01562	2.57e-224	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
PHDLFKOG_01563	3.43e-206	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PHDLFKOG_01564	1.91e-152	yceF	-	-	P	ko:K05794	-	ko00000	membrane
PHDLFKOG_01565	1.27e-76	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PHDLFKOG_01567	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PHDLFKOG_01568	1.85e-59	ylxQ	-	-	J	-	-	-	ribosomal protein
PHDLFKOG_01569	2.02e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
PHDLFKOG_01570	7.38e-273	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
PHDLFKOG_01571	3.81e-110	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
PHDLFKOG_01572	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHDLFKOG_01573	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PHDLFKOG_01574	2.89e-291	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
PHDLFKOG_01575	9.72e-182	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
PHDLFKOG_01576	2.05e-177	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PHDLFKOG_01577	4.96e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PHDLFKOG_01578	1.96e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
PHDLFKOG_01579	3.28e-200	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PHDLFKOG_01580	9.72e-182	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
PHDLFKOG_01581	1.29e-63	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
PHDLFKOG_01582	1.5e-173	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
PHDLFKOG_01583	4.02e-158	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
PHDLFKOG_01584	2.83e-301	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
PHDLFKOG_01585	7.66e-178	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
PHDLFKOG_01586	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_01587	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_01588	1.39e-40	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
PHDLFKOG_01589	3.45e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
PHDLFKOG_01590	1.08e-35	-	-	-	-	-	-	-	-
PHDLFKOG_01591	1.16e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PHDLFKOG_01592	2.14e-189	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
PHDLFKOG_01593	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PHDLFKOG_01594	2.2e-51	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
PHDLFKOG_01595	2.97e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
PHDLFKOG_01596	1.02e-301	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PHDLFKOG_01597	2.45e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PHDLFKOG_01598	1.47e-33	-	-	-	-	-	-	-	-
PHDLFKOG_01599	1.12e-69	-	-	-	-	-	-	-	-
PHDLFKOG_01600	7.44e-232	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PHDLFKOG_01601	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
PHDLFKOG_01602	2.68e-159	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PHDLFKOG_01603	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PHDLFKOG_01604	6.51e-196	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PHDLFKOG_01605	8.93e-223	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01606	5.65e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PHDLFKOG_01607	2.99e-247	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PHDLFKOG_01608	9.22e-49	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHDLFKOG_01609	1.16e-240	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PHDLFKOG_01610	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PHDLFKOG_01611	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
PHDLFKOG_01612	5.83e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
PHDLFKOG_01613	3.26e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
PHDLFKOG_01614	1.1e-158	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
PHDLFKOG_01615	1.63e-148	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
PHDLFKOG_01616	2.45e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PHDLFKOG_01617	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
PHDLFKOG_01618	4.47e-175	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
PHDLFKOG_01619	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PHDLFKOG_01620	2.29e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PHDLFKOG_01621	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PHDLFKOG_01622	3.8e-273	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PHDLFKOG_01623	4.4e-47	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PHDLFKOG_01624	5.09e-148	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
PHDLFKOG_01625	4.46e-156	-	-	-	S	ko:K07001	-	ko00000	Patatin-like phospholipase
PHDLFKOG_01626	8.07e-68	-	-	-	-	-	-	-	-
PHDLFKOG_01627	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
PHDLFKOG_01628	3.59e-97	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PHDLFKOG_01629	4.68e-196	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
PHDLFKOG_01630	2.27e-186	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PHDLFKOG_01631	2.87e-43	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHDLFKOG_01632	2.58e-310	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PHDLFKOG_01633	5.67e-196	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PHDLFKOG_01634	1.29e-87	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PHDLFKOG_01635	8.72e-100	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
PHDLFKOG_01636	4.27e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHDLFKOG_01637	1.51e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
PHDLFKOG_01638	1.6e-63	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
PHDLFKOG_01639	4.18e-73	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
PHDLFKOG_01640	1.18e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
PHDLFKOG_01641	5.41e-43	-	-	-	-	-	-	-	-
PHDLFKOG_01642	1.77e-20	-	-	-	-	-	-	-	-
PHDLFKOG_01643	2.69e-297	-	-	-	S	-	-	-	Membrane
PHDLFKOG_01645	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PHDLFKOG_01646	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PHDLFKOG_01647	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
PHDLFKOG_01648	5.4e-80	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
PHDLFKOG_01649	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
PHDLFKOG_01650	6.73e-305	ynbB	-	-	P	-	-	-	aluminum resistance
PHDLFKOG_01651	3.41e-231	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PHDLFKOG_01652	2.75e-34	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
PHDLFKOG_01653	6.47e-95	yqhL	-	-	P	-	-	-	Rhodanese-like protein
PHDLFKOG_01654	4.82e-227	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
PHDLFKOG_01655	1.37e-54	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
PHDLFKOG_01656	8.99e-157	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
PHDLFKOG_01657	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
PHDLFKOG_01658	0.0	-	-	-	S	-	-	-	Bacterial membrane protein YfhO
PHDLFKOG_01659	1.91e-70	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
PHDLFKOG_01660	3.39e-148	vraR	-	-	K	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
PHDLFKOG_01661	2.79e-234	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHDLFKOG_01662	2.31e-166	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
PHDLFKOG_01663	6.1e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PHDLFKOG_01664	1.98e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
PHDLFKOG_01665	2.75e-267	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PHDLFKOG_01666	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHDLFKOG_01667	4.32e-260	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PHDLFKOG_01668	1.44e-90	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
PHDLFKOG_01669	3.09e-122	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PHDLFKOG_01670	5e-175	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHDLFKOG_01671	1.45e-60	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
PHDLFKOG_01672	9.37e-230	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHDLFKOG_01673	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHDLFKOG_01674	1.01e-157	csrR	-	-	K	-	-	-	response regulator
PHDLFKOG_01675	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PHDLFKOG_01676	1.14e-122	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
PHDLFKOG_01677	3.45e-263	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
PHDLFKOG_01678	1.19e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
PHDLFKOG_01679	1.68e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PHDLFKOG_01680	9.21e-142	yqeK	-	-	H	-	-	-	Hydrolase, HD family
PHDLFKOG_01681	1.19e-150	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PHDLFKOG_01682	7.67e-63	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
PHDLFKOG_01683	9.33e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
PHDLFKOG_01684	4.16e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
PHDLFKOG_01685	4.06e-213	ykcA	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHDLFKOG_01686	3.2e-242	mhqA_2	-	-	E	ko:K15975	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PHDLFKOG_01687	8.79e-156	mhqD	-	-	S	ko:K06999	-	ko00000	Dienelactone hydrolase family
PHDLFKOG_01688	2.91e-229	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
PHDLFKOG_01689	4.79e-129	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
PHDLFKOG_01690	1.44e-74	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PHDLFKOG_01691	1.13e-36	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
PHDLFKOG_01692	2.6e-101	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PHDLFKOG_01693	7.83e-292	spoVK	-	-	O	-	-	-	ATPase family associated with various cellular activities (AAA)
PHDLFKOG_01694	3e-07	-	-	-	-	-	-	-	-
PHDLFKOG_01695	3.94e-45	-	-	-	K	-	-	-	WYL domain
PHDLFKOG_01696	1.19e-160	-	-	-	S	-	-	-	SseB protein N-terminal domain
PHDLFKOG_01697	5.87e-86	-	-	-	-	-	-	-	-
PHDLFKOG_01698	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PHDLFKOG_01699	3.91e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
PHDLFKOG_01700	2.78e-316	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
PHDLFKOG_01701	3.55e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PHDLFKOG_01702	4.88e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PHDLFKOG_01703	5.95e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PHDLFKOG_01704	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PHDLFKOG_01705	1.65e-151	ybhL	-	-	S	ko:K06890	-	ko00000	Inhibitor of apoptosis-promoting Bax1
PHDLFKOG_01706	7.54e-242	-	-	-	S	-	-	-	Cell surface protein
PHDLFKOG_01708	2.02e-174	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PHDLFKOG_01709	0.0	-	-	-	N	-	-	-	domain, Protein
PHDLFKOG_01710	0.0	XK27_00195	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_01711	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
PHDLFKOG_01712	7.57e-34	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PHDLFKOG_01713	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
PHDLFKOG_01715	1.63e-146	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PHDLFKOG_01716	4.38e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
PHDLFKOG_01718	1.11e-154	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PHDLFKOG_01719	3.86e-190	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
PHDLFKOG_01720	0.000128	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_01721	4.2e-284	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_01722	3.53e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01723	1.14e-96	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
PHDLFKOG_01724	2.79e-77	-	-	-	S	-	-	-	YtxH-like protein
PHDLFKOG_01725	1.02e-202	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHDLFKOG_01726	3.57e-233	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
PHDLFKOG_01727	3.88e-73	-	-	-	S	-	-	-	Control of competence regulator ComK, YlbF/YmcA
PHDLFKOG_01728	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
PHDLFKOG_01729	1.4e-198	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
PHDLFKOG_01730	2.72e-97	argR1	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
PHDLFKOG_01731	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
PHDLFKOG_01733	3.28e-87	-	-	-	-	-	-	-	-
PHDLFKOG_01734	1.93e-30	-	-	-	-	-	-	-	-
PHDLFKOG_01735	3.26e-226	pyrD	1.3.5.2, 1.3.98.1	-	F	ko:K00226,ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
PHDLFKOG_01736	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
PHDLFKOG_01737	1.1e-156	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PHDLFKOG_01738	1.8e-86	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PHDLFKOG_01739	1.63e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
PHDLFKOG_01740	9.97e-119	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
PHDLFKOG_01741	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
PHDLFKOG_01742	5.63e-178	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_01743	5.24e-158	rrp1	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
PHDLFKOG_01744	5.95e-263	-	-	-	T	ko:K19168	-	ko00000,ko02048	His Kinase A (phosphoacceptor) domain
PHDLFKOG_01745	1.09e-139	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PHDLFKOG_01746	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5	-	P	ko:K01533,ko:K01534	-	ko00000,ko01000	P-type ATPase
PHDLFKOG_01747	6.75e-101	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
PHDLFKOG_01748	1.59e-286	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
PHDLFKOG_01749	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
PHDLFKOG_01750	9.63e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PHDLFKOG_01751	6.18e-238	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
PHDLFKOG_01752	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PHDLFKOG_01753	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHDLFKOG_01754	3.56e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHDLFKOG_01755	5.52e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PHDLFKOG_01756	1.9e-171	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
PHDLFKOG_01757	5.81e-272	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PHDLFKOG_01758	6.02e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PHDLFKOG_01759	2.72e-135	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
PHDLFKOG_01761	0.0	iolT	-	-	EGP	ko:K06609	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PHDLFKOG_01762	2.98e-18	-	-	-	-	-	-	-	-
PHDLFKOG_01763	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PHDLFKOG_01764	1.02e-51	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
PHDLFKOG_01765	6.69e-39	-	-	-	-	-	-	-	-
PHDLFKOG_01766	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
PHDLFKOG_01767	2.87e-62	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PHDLFKOG_01768	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PHDLFKOG_01769	1.88e-307	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
PHDLFKOG_01770	4.36e-264	yueF	-	-	S	-	-	-	AI-2E family transporter
PHDLFKOG_01771	1.96e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01772	1.16e-124	-	-	-	-	-	-	-	-
PHDLFKOG_01773	1.73e-134	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
PHDLFKOG_01774	7.6e-176	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
PHDLFKOG_01775	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_01776	2.24e-84	-	-	-	-	-	-	-	-
PHDLFKOG_01777	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PHDLFKOG_01778	2.78e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
PHDLFKOG_01779	0.0	poxL	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PHDLFKOG_01781	8.72e-279	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
PHDLFKOG_01782	4.29e-265	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
PHDLFKOG_01783	7.3e-268	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
PHDLFKOG_01784	6.7e-62	-	-	-	-	-	-	-	-
PHDLFKOG_01785	5.52e-204	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
PHDLFKOG_01786	1.49e-132	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
PHDLFKOG_01787	2.96e-204	-	-	-	G	-	-	-	Aldose 1-epimerase
PHDLFKOG_01788	4.58e-269	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
PHDLFKOG_01789	6.88e-129	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
PHDLFKOG_01791	1.4e-105	-	-	-	K	-	-	-	FR47-like protein
PHDLFKOG_01792	8.49e-105	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
PHDLFKOG_01793	1.59e-165	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01794	3.57e-175	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
PHDLFKOG_01795	1.88e-225	XK27_08835	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_01796	2.37e-95	-	-	-	-	-	-	-	-
PHDLFKOG_01797	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PHDLFKOG_01798	1.01e-275	-	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_01799	5.9e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PHDLFKOG_01800	1.3e-284	-	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_01801	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHDLFKOG_01802	2.79e-162	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
PHDLFKOG_01803	2.49e-278	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
PHDLFKOG_01804	7.93e-178	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PHDLFKOG_01805	0.0	yuxL	3.4.19.1	-	E	ko:K01303	-	ko00000,ko01000,ko01002	Prolyl oligopeptidase family
PHDLFKOG_01806	0.0	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
PHDLFKOG_01807	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_01809	1.92e-200	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PHDLFKOG_01810	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
PHDLFKOG_01811	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01812	2.43e-87	-	-	-	-	-	-	-	-
PHDLFKOG_01813	1.39e-96	-	-	-	S	-	-	-	function, without similarity to other proteins
PHDLFKOG_01814	0.0	-	-	-	G	-	-	-	MFS/sugar transport protein
PHDLFKOG_01815	2.35e-295	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
PHDLFKOG_01816	3.89e-75	-	-	-	-	-	-	-	-
PHDLFKOG_01817	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
PHDLFKOG_01818	4.52e-34	-	-	-	S	-	-	-	Virus attachment protein p12 family
PHDLFKOG_01819	8.39e-314	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PHDLFKOG_01820	9.93e-175	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
PHDLFKOG_01821	3.58e-128	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA
PHDLFKOG_01822	1.42e-169	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PHDLFKOG_01823	1.12e-115	-	-	-	E	-	-	-	AAA domain
PHDLFKOG_01826	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01827	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01828	2.62e-152	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
PHDLFKOG_01829	2.78e-118	-	-	-	S	-	-	-	MucBP domain
PHDLFKOG_01830	5.24e-113	-	-	-	-	-	-	-	-
PHDLFKOG_01834	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PHDLFKOG_01837	1.45e-46	-	-	-	-	-	-	-	-
PHDLFKOG_01838	5.08e-283	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PHDLFKOG_01839	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_01840	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_01841	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
PHDLFKOG_01843	1.97e-168	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
PHDLFKOG_01844	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
PHDLFKOG_01845	1.96e-126	-	-	-	-	-	-	-	-
PHDLFKOG_01846	1.69e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PHDLFKOG_01847	2.4e-07	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_01848	9.53e-241	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
PHDLFKOG_01849	1.42e-132	-	-	-	-	-	-	-	-
PHDLFKOG_01850	1.43e-25	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PHDLFKOG_01851	3.21e-204	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
PHDLFKOG_01852	1.2e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
PHDLFKOG_01853	1.92e-83	-	-	-	-	-	-	-	-
PHDLFKOG_01854	3.93e-90	-	-	-	-	-	-	-	-
PHDLFKOG_01855	4.44e-62	-	-	-	-	-	-	-	-
PHDLFKOG_01856	2.83e-202	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PHDLFKOG_01857	6.87e-162	citR	-	-	K	-	-	-	FCD
PHDLFKOG_01858	0.0	oadA	4.1.1.3	-	C	ko:K01571	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Conserved carboxylase domain
PHDLFKOG_01859	4.83e-131	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PHDLFKOG_01860	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
PHDLFKOG_01861	2.5e-199	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
PHDLFKOG_01862	4.85e-65	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
PHDLFKOG_01863	4.66e-232	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PHDLFKOG_01864	4.63e-07	-	-	-	-	-	-	-	-
PHDLFKOG_01865	1.6e-250	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Na+-transporting oxaloacetate decarboxylase beta subunit
PHDLFKOG_01866	1.44e-57	oadG	-	-	I	-	-	-	Biotin-requiring enzyme
PHDLFKOG_01867	5.72e-69	-	-	-	-	-	-	-	-
PHDLFKOG_01868	2.47e-308	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
PHDLFKOG_01869	4.38e-56	-	-	-	-	-	-	-	-
PHDLFKOG_01870	2.75e-123	kptA	-	-	J	ko:K07559	-	ko00000,ko01000,ko03016	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
PHDLFKOG_01871	1.36e-112	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01872	1.29e-135	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
PHDLFKOG_01873	7.63e-74	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PHDLFKOG_01874	4.82e-83	ORF00048	-	-	-	-	-	-	-
PHDLFKOG_01875	5e-174	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
PHDLFKOG_01876	5.54e-214	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_01877	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
PHDLFKOG_01878	9.85e-147	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
PHDLFKOG_01879	0.0	ypiB	-	-	EGP	-	-	-	Major Facilitator
PHDLFKOG_01880	6.02e-163	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
PHDLFKOG_01881	2.15e-237	-	-	-	K	-	-	-	Helix-turn-helix domain
PHDLFKOG_01882	6.17e-203	-	-	-	S	-	-	-	Alpha beta hydrolase
PHDLFKOG_01883	5.73e-82	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
PHDLFKOG_01884	1.49e-164	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_01886	1.9e-193	-	-	-	-	-	-	-	-
PHDLFKOG_01887	7.16e-113	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_01888	2.84e-207	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
PHDLFKOG_01889	3.1e-247	-	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
PHDLFKOG_01890	5.22e-65	-	-	-	-	-	-	-	-
PHDLFKOG_01891	3.48e-219	-	-	-	P	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
PHDLFKOG_01892	5.52e-215	-	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PHDLFKOG_01893	0.0	-	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
PHDLFKOG_01894	6.2e-48	-	-	-	-	-	-	-	-
PHDLFKOG_01895	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PHDLFKOG_01896	0.0	-	-	-	V	ko:K06147,ko:K06148,ko:K11085,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter transmembrane region
PHDLFKOG_01897	1.87e-88	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PHDLFKOG_01898	1.04e-175	-	2.7.1.39	-	S	ko:K02204	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Phosphotransferase enzyme family
PHDLFKOG_01899	3e-154	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
PHDLFKOG_01900	4.47e-32	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
PHDLFKOG_01902	0.0	-	-	-	M	-	-	-	LysM domain
PHDLFKOG_01904	6.65e-64	lciIC	-	-	K	-	-	-	Helix-turn-helix domain
PHDLFKOG_01905	1.55e-117	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
PHDLFKOG_01906	1.29e-44	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
PHDLFKOG_01908	9.36e-35	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PHDLFKOG_01913	1.83e-15	-	-	-	M	-	-	-	LysM domain
PHDLFKOG_01914	1.92e-67	-	-	-	-	-	-	-	-
PHDLFKOG_01915	9.19e-96	-	-	-	K	-	-	-	Putative DNA-binding domain
PHDLFKOG_01916	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01917	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01919	4.52e-54	-	-	-	S	-	-	-	Abortive infection C-terminus
PHDLFKOG_01920	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
PHDLFKOG_01921	3.82e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
PHDLFKOG_01922	4.69e-70	-	-	-	-	-	-	-	-
PHDLFKOG_01923	2.59e-55	-	-	-	-	-	-	-	-
PHDLFKOG_01924	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
PHDLFKOG_01925	6.86e-108	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
PHDLFKOG_01926	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
PHDLFKOG_01927	7.41e-37	-	-	-	-	-	-	-	-
PHDLFKOG_01928	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
PHDLFKOG_01929	3.98e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PHDLFKOG_01930	9.11e-106	yjhE	-	-	S	-	-	-	Phage tail protein
PHDLFKOG_01931	1.31e-304	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PHDLFKOG_01932	1.02e-234	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
PHDLFKOG_01933	4.02e-165	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
PHDLFKOG_01934	1.69e-218	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PHDLFKOG_01935	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PHDLFKOG_01936	5.4e-174	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01937	0.0	-	-	-	E	-	-	-	Amino Acid
PHDLFKOG_01938	4.57e-212	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
PHDLFKOG_01939	1.53e-302	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PHDLFKOG_01940	1.33e-140	nodB3	-	-	G	-	-	-	Polysaccharide deacetylase
PHDLFKOG_01941	0.0	-	-	-	M	-	-	-	Sulfatase
PHDLFKOG_01942	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01943	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01944	1.7e-221	-	-	-	S	-	-	-	EpsG family
PHDLFKOG_01945	3.25e-107	-	-	-	D	-	-	-	Capsular exopolysaccharide family
PHDLFKOG_01946	1.45e-126	ywqC	-	-	M	ko:K16554	ko05111,map05111	ko00000,ko00001,ko02000	capsule polysaccharide biosynthetic process
PHDLFKOG_01947	6.29e-314	-	-	-	S	-	-	-	polysaccharide biosynthetic process
PHDLFKOG_01948	2.61e-252	-	-	-	M	-	-	-	Glycosyl transferases group 1
PHDLFKOG_01949	5.35e-151	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_01950	1.03e-275	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
PHDLFKOG_01951	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
PHDLFKOG_01952	1.42e-224	-	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
PHDLFKOG_01953	3.19e-142	-	-	-	M	-	-	-	Acyltransferase family
PHDLFKOG_01954	8.66e-202	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
PHDLFKOG_01955	4.48e-254	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PHDLFKOG_01956	1.41e-115	-	-	-	-	-	-	-	-
PHDLFKOG_01957	0.0	cps2E	-	-	M	-	-	-	Bacterial sugar transferase
PHDLFKOG_01958	1.09e-170	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
PHDLFKOG_01959	7.75e-146	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
PHDLFKOG_01960	4.63e-225	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
PHDLFKOG_01961	7.92e-142	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01962	1.18e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_01963	5.86e-189	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
PHDLFKOG_01965	1.05e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_01966	1.95e-221	-	-	-	-	-	-	-	-
PHDLFKOG_01967	0.000417	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
PHDLFKOG_01968	1.93e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
PHDLFKOG_01969	1.1e-13	-	-	-	-	-	-	-	-
PHDLFKOG_01970	8.86e-145	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
PHDLFKOG_01971	9.55e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_01972	8.57e-203	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
PHDLFKOG_01973	6.53e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PHDLFKOG_01974	5.22e-207	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHDLFKOG_01975	1.38e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
PHDLFKOG_01976	6.3e-222	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHDLFKOG_01977	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
PHDLFKOG_01978	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PHDLFKOG_01979	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
PHDLFKOG_01980	3.02e-258	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
PHDLFKOG_01981	1.51e-254	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PHDLFKOG_01982	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PHDLFKOG_01983	1.02e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
PHDLFKOG_01984	1.8e-180	-	-	-	M	-	-	-	Sortase family
PHDLFKOG_01985	3.72e-186	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
PHDLFKOG_01986	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	phosphatase activity
PHDLFKOG_01987	2.27e-85	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
PHDLFKOG_01988	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
PHDLFKOG_01989	1.95e-197	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
PHDLFKOG_01990	1.09e-174	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
PHDLFKOG_01991	6.35e-200	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PHDLFKOG_01992	9.81e-32	-	-	-	-	-	-	-	-
PHDLFKOG_01993	5.68e-76	-	-	-	L	ko:K07484	-	ko00000	IS66 Orf2 like protein
PHDLFKOG_01994	1.22e-81	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PHDLFKOG_01995	5.31e-197	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
PHDLFKOG_01996	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_01997	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_01998	2.57e-104	rfbP	-	-	M	-	-	-	Bacterial sugar transferase
PHDLFKOG_01999	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_02000	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_02001	1.17e-90	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
PHDLFKOG_02002	3.86e-85	cps2I	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
PHDLFKOG_02003	6.3e-33	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
PHDLFKOG_02004	4.87e-32	-	-	-	S	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_02005	2.78e-76	-	-	-	M	-	-	-	Glycosyl transferases group 1
PHDLFKOG_02006	8.46e-18	-	-	-	S	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_02008	1.43e-18	-	-	-	M	-	-	-	Glycosyltransferase like family 2
PHDLFKOG_02009	5.97e-136	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
PHDLFKOG_02010	4.63e-139	epsB	-	-	M	-	-	-	biosynthesis protein
PHDLFKOG_02011	1.38e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
PHDLFKOG_02012	5.97e-106	ccl	-	-	S	-	-	-	QueT transporter
PHDLFKOG_02013	1.09e-161	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
PHDLFKOG_02014	8.55e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
PHDLFKOG_02015	3.39e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
PHDLFKOG_02016	8.42e-149	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
PHDLFKOG_02017	7.74e-232	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PHDLFKOG_02018	2.89e-250	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
PHDLFKOG_02019	3.36e-224	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHDLFKOG_02020	1.15e-207	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
PHDLFKOG_02021	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PHDLFKOG_02022	1.97e-61	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_02023	6.86e-196	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_02024	5.82e-130	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PHDLFKOG_02025	2.6e-168	lutC	-	-	S	ko:K00782	-	ko00000	LUD domain
PHDLFKOG_02026	0.0	lutB	-	-	C	ko:K18929	-	ko00000	4Fe-4S dicluster domain
PHDLFKOG_02027	3.29e-188	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
PHDLFKOG_02028	1.32e-131	-	-	-	-	-	-	-	-
PHDLFKOG_02029	6.5e-71	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
PHDLFKOG_02030	6.25e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PHDLFKOG_02031	1.92e-92	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PHDLFKOG_02032	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHDLFKOG_02033	0.0	galA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
PHDLFKOG_02034	4.11e-171	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
PHDLFKOG_02035	6.82e-170	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
PHDLFKOG_02036	0.0	-	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Helix-hairpin-helix containing domain
PHDLFKOG_02037	1.46e-134	-	-	-	-	-	-	-	-
PHDLFKOG_02038	2.56e-126	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
PHDLFKOG_02039	1.38e-185	frlD1	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
PHDLFKOG_02040	2.51e-129	-	-	-	G	-	-	-	Phosphodiester glycosidase
PHDLFKOG_02041	5.03e-180	-	-	-	G	-	-	-	Phosphodiester glycosidase
PHDLFKOG_02042	0.0	hyuA	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
PHDLFKOG_02043	9.89e-264	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
PHDLFKOG_02044	8.08e-282	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
PHDLFKOG_02045	3.27e-167	-	-	-	-	-	-	-	-
PHDLFKOG_02046	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
PHDLFKOG_02047	0.0	-	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	Putative ATP-dependent Lon protease
PHDLFKOG_02048	0.0	-	-	-	S	-	-	-	PglZ domain
PHDLFKOG_02049	0.0	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
PHDLFKOG_02050	5.82e-17	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHDLFKOG_02051	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_02052	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_02053	1.75e-150	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
PHDLFKOG_02054	0.0	-	-	-	V	-	-	-	Eco57I restriction-modification methylase
PHDLFKOG_02055	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
PHDLFKOG_02056	8.22e-138	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
PHDLFKOG_02057	1.16e-135	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
PHDLFKOG_02058	2.87e-270	-	-	-	-	-	-	-	-
PHDLFKOG_02059	0.0	pip	-	-	V	ko:K01421	-	ko00000	domain protein
PHDLFKOG_02060	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_02061	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHDLFKOG_02062	4.42e-225	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
PHDLFKOG_02063	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
PHDLFKOG_02065	6.17e-203	-	-	-	GM	-	-	-	NmrA-like family
PHDLFKOG_02066	1.54e-294	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
PHDLFKOG_02067	7.18e-186	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
PHDLFKOG_02068	2.72e-197	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PHDLFKOG_02069	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
PHDLFKOG_02070	4.77e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PHDLFKOG_02071	2.52e-87	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PHDLFKOG_02072	4.03e-283	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PHDLFKOG_02073	2.03e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
PHDLFKOG_02074	1.25e-211	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
PHDLFKOG_02075	3.91e-220	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
PHDLFKOG_02076	5.61e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PHDLFKOG_02077	2.03e-223	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PHDLFKOG_02078	4.21e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
PHDLFKOG_02079	7.93e-94	-	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
PHDLFKOG_02080	4.22e-245	-	-	-	I	-	-	-	carboxylic ester hydrolase activity
PHDLFKOG_02081	5.21e-145	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
PHDLFKOG_02082	1.61e-117	-	-	-	C	-	-	-	Iron-containing alcohol dehydrogenase
PHDLFKOG_02083	1.88e-83	-	-	-	P	-	-	-	Rhodanese-like domain
PHDLFKOG_02084	2.45e-109	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
PHDLFKOG_02085	9.17e-37	-	-	-	-	-	-	-	-
PHDLFKOG_02086	8.12e-90	-	-	-	K	ko:K18909	-	ko00000,ko00002,ko01504,ko03000	MarR family
PHDLFKOG_02087	3.25e-13	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
PHDLFKOG_02088	8.41e-236	-	-	-	S	-	-	-	Putative esterase
PHDLFKOG_02089	9.23e-241	-	-	-	-	-	-	-	-
PHDLFKOG_02090	5.56e-136	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
PHDLFKOG_02091	7.19e-113	-	-	-	F	-	-	-	NUDIX domain
PHDLFKOG_02092	1.15e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHDLFKOG_02093	1.39e-40	-	-	-	-	-	-	-	-
PHDLFKOG_02094	4.05e-201	-	-	-	S	-	-	-	zinc-ribbon domain
PHDLFKOG_02095	5.46e-258	pbpX	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_02096	1.02e-238	ydbI	-	-	K	-	-	-	AI-2E family transporter
PHDLFKOG_02097	2.05e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PHDLFKOG_02098	3.45e-86	gtcA2	-	-	S	-	-	-	Teichoic acid glycosylation protein
PHDLFKOG_02099	0.0	-	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
PHDLFKOG_02100	3.5e-219	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PHDLFKOG_02101	1.23e-190	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
PHDLFKOG_02102	1.85e-284	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
PHDLFKOG_02103	9.41e-175	sfsA	-	-	S	ko:K06206	-	ko00000	Belongs to the SfsA family
PHDLFKOG_02104	1.5e-95	usp1	-	-	T	-	-	-	Universal stress protein family
PHDLFKOG_02105	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
PHDLFKOG_02106	8.12e-205	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PHDLFKOG_02107	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
PHDLFKOG_02108	7.93e-291	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
PHDLFKOG_02109	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
PHDLFKOG_02110	4.95e-286	floL	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH domain / Band 7 family
PHDLFKOG_02111	6.68e-89	-	-	-	-	-	-	-	-
PHDLFKOG_02112	1.16e-211	pfoSR	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
PHDLFKOG_02113	6.32e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHDLFKOG_02114	6.61e-277	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHDLFKOG_02115	3.3e-162	WQ51_05710	-	-	S	-	-	-	Mitochondrial biogenesis AIM24
PHDLFKOG_02116	1.06e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
PHDLFKOG_02117	2.96e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_02118	2.91e-223	-	-	-	V	ko:K01421	-	ko00000	domain protein
PHDLFKOG_02119	4.41e-220	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PHDLFKOG_02120	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
PHDLFKOG_02121	2.44e-06	lacC	2.7.1.144	-	H	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PHDLFKOG_02122	4.35e-263	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
PHDLFKOG_02123	1.69e-203	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PHDLFKOG_02124	4.43e-224	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PHDLFKOG_02125	1.35e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PHDLFKOG_02126	1.04e-213	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_02127	1.39e-278	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PHDLFKOG_02128	1.13e-84	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PHDLFKOG_02129	7.25e-206	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_02130	6.91e-149	-	-	-	I	-	-	-	ABC-2 family transporter protein
PHDLFKOG_02131	1.69e-186	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
PHDLFKOG_02132	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
PHDLFKOG_02133	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
PHDLFKOG_02134	1.99e-204	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
PHDLFKOG_02135	0.0	msbA9	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PHDLFKOG_02136	0.0	cydD1	-	-	CO	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PHDLFKOG_02137	6.36e-98	-	-	-	S	-	-	-	NusG domain II
PHDLFKOG_02138	1.77e-227	-	-	-	M	-	-	-	Peptidoglycan-binding domain 1 protein
PHDLFKOG_02140	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PHDLFKOG_02141	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PHDLFKOG_02142	4.14e-232	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
PHDLFKOG_02143	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
PHDLFKOG_02144	3.89e-302	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	pyrimidine-nucleoside phosphorylase
PHDLFKOG_02145	8.01e-231	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PHDLFKOG_02146	3.38e-50	-	-	-	-	-	-	-	-
PHDLFKOG_02147	5.18e-114	-	-	-	-	-	-	-	-
PHDLFKOG_02148	1.57e-34	-	-	-	-	-	-	-	-
PHDLFKOG_02149	5.69e-207	-	-	-	EG	-	-	-	EamA-like transporter family
PHDLFKOG_02150	2.08e-145	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
PHDLFKOG_02151	1.94e-100	usp5	-	-	T	-	-	-	universal stress protein
PHDLFKOG_02152	8.34e-86	-	-	-	K	-	-	-	Helix-turn-helix domain
PHDLFKOG_02153	4.49e-187	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PHDLFKOG_02154	5.06e-282	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Domain of unknown function (DUF1730)
PHDLFKOG_02155	2.11e-82	-	-	-	-	-	-	-	-
PHDLFKOG_02156	2.46e-114	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
PHDLFKOG_02158	5.22e-132	-	-	-	Q	-	-	-	methyltransferase
PHDLFKOG_02159	3.75e-142	-	-	-	T	-	-	-	Sh3 type 3 domain protein
PHDLFKOG_02160	1.71e-145	-	-	-	F	-	-	-	glutamine amidotransferase
PHDLFKOG_02161	1.82e-175	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
PHDLFKOG_02162	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
PHDLFKOG_02163	2.21e-184	-	-	-	S	-	-	-	Alpha beta hydrolase
PHDLFKOG_02164	3.95e-253	-	-	-	I	-	-	-	Acyltransferase
PHDLFKOG_02165	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
PHDLFKOG_02166	1.08e-107	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
PHDLFKOG_02167	1.43e-123	maf	-	-	D	ko:K06287	-	ko00000	nucleoside-triphosphate diphosphatase activity
PHDLFKOG_02168	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PHDLFKOG_02169	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PHDLFKOG_02171	0.0	ydaO	-	-	E	-	-	-	amino acid
PHDLFKOG_02172	7.56e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF1827)
PHDLFKOG_02173	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PHDLFKOG_02174	1.7e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PHDLFKOG_02175	1.23e-142	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PHDLFKOG_02176	4.11e-251	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
PHDLFKOG_02177	6.27e-248	-	-	-	-	-	-	-	-
PHDLFKOG_02178	4.17e-204	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_02179	7.06e-81	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PHDLFKOG_02180	7.76e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PHDLFKOG_02181	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
PHDLFKOG_02182	6.92e-66	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_02183	4.36e-240	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PHDLFKOG_02184	1.06e-127	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
PHDLFKOG_02185	3.82e-168	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
PHDLFKOG_02186	7.32e-153	-	-	-	-	-	-	-	-
PHDLFKOG_02187	4.02e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
PHDLFKOG_02188	8.71e-232	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
PHDLFKOG_02189	4.51e-184	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
PHDLFKOG_02190	1.56e-194	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PHDLFKOG_02191	2.27e-75	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
PHDLFKOG_02192	2.38e-225	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
PHDLFKOG_02193	2.31e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
PHDLFKOG_02194	2.6e-149	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PHDLFKOG_02195	1.35e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
PHDLFKOG_02196	2.17e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PHDLFKOG_02197	2.29e-50	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PHDLFKOG_02198	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PHDLFKOG_02199	5.13e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PHDLFKOG_02200	5.69e-65	-	-	-	-	-	-	-	-
PHDLFKOG_02201	3.34e-139	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
PHDLFKOG_02202	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PHDLFKOG_02203	2.27e-89	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PHDLFKOG_02204	3.78e-170	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PHDLFKOG_02206	7.81e-88	-	-	-	-	-	-	-	-
PHDLFKOG_02207	1.22e-220	ccpB	-	-	K	-	-	-	lacI family
PHDLFKOG_02208	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PHDLFKOG_02209	1.62e-199	-	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PHDLFKOG_02210	4.57e-73	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PHDLFKOG_02211	6.19e-109	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PHDLFKOG_02212	8.53e-287	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
PHDLFKOG_02213	5.9e-193	-	-	-	K	-	-	-	acetyltransferase
PHDLFKOG_02214	2.4e-117	-	-	-	-	-	-	-	-
PHDLFKOG_02215	1.03e-281	yceI	-	-	G	ko:K08369	-	ko00000,ko02000	Sugar (and other) transporter
PHDLFKOG_02216	1.21e-39	-	-	-	-	-	-	-	-
PHDLFKOG_02217	0.0	-	-	-	-	-	-	-	-
PHDLFKOG_02218	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
PHDLFKOG_02219	0.0	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PHDLFKOG_02220	4.16e-65	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PHDLFKOG_02221	3.3e-228	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
PHDLFKOG_02222	4.45e-122	yqaB	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_02223	1.33e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PHDLFKOG_02224	1.97e-92	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PHDLFKOG_02225	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
PHDLFKOG_02226	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
PHDLFKOG_02227	5.42e-117	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Cobalamin adenosyltransferase
PHDLFKOG_02228	5.8e-113	-	-	-	S	ko:K16927	-	ko00000,ko00002,ko02000	ECF transporter, substrate-specific component
PHDLFKOG_02229	2.89e-82	-	-	-	S	-	-	-	Domain of unknown function (DUF4430)
PHDLFKOG_02230	0.0	rtpR	1.17.4.2	-	F	ko:K00527	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	ribonucleoside-triphosphate reductase activity
PHDLFKOG_02231	6.51e-103	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
PHDLFKOG_02232	1.64e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
PHDLFKOG_02233	8e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
PHDLFKOG_02234	2.53e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PHDLFKOG_02235	3.75e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
PHDLFKOG_02236	2.18e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
PHDLFKOG_02237	7.19e-209	menA	2.5.1.74	-	M	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
PHDLFKOG_02239	3.78e-248	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PHDLFKOG_02240	1.15e-280	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
PHDLFKOG_02241	7.5e-190	cad	-	-	S	ko:K20379	ko02024,map02024	ko00000,ko00001	FMN_bind
PHDLFKOG_02242	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PHDLFKOG_02243	2.87e-106	-	-	-	S	-	-	-	NusG domain II
PHDLFKOG_02244	7.23e-128	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
PHDLFKOG_02245	9.42e-232	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
PHDLFKOG_02246	9.18e-105	-	-	-	-	-	-	-	-
PHDLFKOG_02247	3.41e-187	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
PHDLFKOG_02248	5.81e-125	-	-	-	-	-	-	-	-
PHDLFKOG_02249	1.5e-148	-	-	-	-	-	-	-	-
PHDLFKOG_02250	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_02251	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_02252	3.67e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_02253	2.02e-273	-	-	-	-	-	-	-	-
PHDLFKOG_02254	4.05e-247	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
PHDLFKOG_02255	2.58e-155	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	Rossmann-like domain
PHDLFKOG_02256	1.13e-128	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PHDLFKOG_02257	1.52e-100	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
PHDLFKOG_02258	1.45e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
PHDLFKOG_02259	2.6e-185	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PHDLFKOG_02260	2.3e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PHDLFKOG_02261	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PHDLFKOG_02262	4.31e-312	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
PHDLFKOG_02263	5.16e-127	-	-	-	-	-	-	-	-
PHDLFKOG_02265	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PHDLFKOG_02266	1.36e-179	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
PHDLFKOG_02267	2.65e-224	-	-	-	S	-	-	-	Membrane
PHDLFKOG_02268	3.54e-82	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
PHDLFKOG_02269	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PHDLFKOG_02270	7.07e-291	inlJ	-	-	M	-	-	-	MucBP domain
PHDLFKOG_02271	6.42e-88	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PHDLFKOG_02272	1.39e-120	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_02273	1.12e-138	-	-	-	K	-	-	-	sequence-specific DNA binding
PHDLFKOG_02274	1.06e-258	yacL	-	-	S	-	-	-	domain protein
PHDLFKOG_02275	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PHDLFKOG_02276	4.49e-130	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTPase
PHDLFKOG_02277	2.37e-65	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
PHDLFKOG_02278	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
PHDLFKOG_02279	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
PHDLFKOG_02280	1.42e-249	-	-	-	-	-	-	-	-
PHDLFKOG_02281	7.65e-272	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
PHDLFKOG_02282	2.55e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_02283	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
PHDLFKOG_02284	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
PHDLFKOG_02285	2.36e-119	ccpN	-	-	K	-	-	-	Domain in cystathionine beta-synthase and other proteins.
PHDLFKOG_02286	9.8e-158	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PHDLFKOG_02287	1.1e-256	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
PHDLFKOG_02288	5.45e-61	-	-	-	-	-	-	-	-
PHDLFKOG_02289	1.47e-177	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PHDLFKOG_02290	7e-10	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PHDLFKOG_02291	9.49e-26	-	-	-	S	-	-	-	CsbD-like
PHDLFKOG_02292	9.56e-189	-	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
PHDLFKOG_02293	3.49e-242	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
PHDLFKOG_02294	4.06e-146	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphorylase superfamily
PHDLFKOG_02295	3.92e-218	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
PHDLFKOG_02296	9.32e-118	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
PHDLFKOG_02298	2.13e-44	-	-	-	-	-	-	-	-
PHDLFKOG_02299	4.69e-46	-	-	-	-	-	-	-	-
PHDLFKOG_02300	4.93e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PHDLFKOG_02301	5.56e-287	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PHDLFKOG_02302	1.38e-189	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PHDLFKOG_02304	3.96e-120	-	-	-	-	-	-	-	-
PHDLFKOG_02305	3.66e-36	-	-	-	V	-	-	-	MacB-like periplasmic core domain
PHDLFKOG_02306	6.62e-69	salX	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_02308	1.16e-179	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
PHDLFKOG_02309	0.0	-	-	-	M	-	-	-	Cna protein B-type domain
PHDLFKOG_02310	0.0	-	-	-	M	-	-	-	domain protein
PHDLFKOG_02311	0.0	-	-	-	M	-	-	-	domain protein
PHDLFKOG_02312	4.45e-133	-	-	-	-	-	-	-	-
PHDLFKOG_02313	4.38e-285	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
PHDLFKOG_02314	4.88e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
PHDLFKOG_02315	9.02e-125	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHDLFKOG_02316	5.62e-75	padR	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
PHDLFKOG_02317	5.59e-176	-	-	-	-	-	-	-	-
PHDLFKOG_02318	1.93e-170	-	-	-	-	-	-	-	-
PHDLFKOG_02319	1.23e-58	-	-	-	S	-	-	-	Enterocin A Immunity
PHDLFKOG_02320	1.07e-237	tas	-	-	C	-	-	-	Aldo/keto reductase family
PHDLFKOG_02321	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
PHDLFKOG_02322	5.9e-78	-	-	-	-	-	-	-	-
PHDLFKOG_02323	3.87e-301	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
PHDLFKOG_02324	0.0	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PHDLFKOG_02326	5.99e-287	comD	2.7.13.3	-	T	ko:K07706,ko:K12294	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
PHDLFKOG_02327	1.58e-170	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PHDLFKOG_02328	1.3e-59	-	-	-	S	-	-	-	Enterocin A Immunity
PHDLFKOG_02329	1.59e-30	-	-	-	-	-	-	-	-
PHDLFKOG_02333	8.4e-170	-	-	-	S	-	-	-	CAAX protease self-immunity
PHDLFKOG_02334	2.35e-91	-	-	-	K	-	-	-	Transcriptional regulator
PHDLFKOG_02335	0.0	norB	-	-	EGP	ko:K08170	-	ko00000,ko00002,ko01504,ko02000	Major Facilitator Superfamily
PHDLFKOG_02336	1.05e-70	-	-	-	-	-	-	-	-
PHDLFKOG_02337	1.59e-71	-	-	-	S	-	-	-	Enterocin A Immunity
PHDLFKOG_02338	3.98e-229	ydhF	-	-	S	-	-	-	Aldo keto reductase
PHDLFKOG_02339	1.49e-167	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
PHDLFKOG_02340	1.61e-274	yqiG	-	-	C	-	-	-	Oxidoreductase
PHDLFKOG_02341	5.39e-32	-	-	-	S	-	-	-	Short C-terminal domain
PHDLFKOG_02342	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PHDLFKOG_02343	2.58e-171	-	-	-	-	-	-	-	-
PHDLFKOG_02344	7.48e-25	-	-	-	-	-	-	-	-
PHDLFKOG_02345	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
PHDLFKOG_02346	1.6e-54	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PHDLFKOG_02347	0.0	atp2C1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
PHDLFKOG_02348	4.42e-84	-	-	-	-	-	-	-	-
PHDLFKOG_02349	1.61e-288	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_02350	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
PHDLFKOG_02351	2.5e-34	-	-	-	-	-	-	-	-
PHDLFKOG_02352	2.4e-144	-	-	-	P	-	-	-	Cation efflux family
PHDLFKOG_02353	1.68e-67	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
PHDLFKOG_02354	1.55e-224	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PHDLFKOG_02355	9.44e-186	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
PHDLFKOG_02356	1.61e-168	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
PHDLFKOG_02357	8.32e-56	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PHDLFKOG_02358	2.35e-215	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PHDLFKOG_02359	1.4e-152	-	-	-	GM	-	-	-	NmrA-like family
PHDLFKOG_02360	7.54e-113	-	-	-	-	-	-	-	-
PHDLFKOG_02361	5.73e-209	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
PHDLFKOG_02362	2.99e-27	-	-	-	-	-	-	-	-
PHDLFKOG_02364	3.3e-70	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHDLFKOG_02365	5.96e-87	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PHDLFKOG_02366	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
PHDLFKOG_02367	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase concanavalin-like domain
PHDLFKOG_02368	2.26e-218	ssuA	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	NMT1-like family
PHDLFKOG_02369	0.0	-	6.2.1.48	-	IQ	ko:K02182	-	ko00000,ko01000	AMP-binding enzyme C-terminal domain
PHDLFKOG_02370	5.68e-298	-	-	-	I	-	-	-	Acyltransferase family
PHDLFKOG_02371	5.81e-155	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_02372	6.12e-190	ssuC	-	-	U	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
PHDLFKOG_02373	1.06e-156	-	-	-	S	-	-	-	B3/4 domain
PHDLFKOG_02375	3.92e-28	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
PHDLFKOG_02377	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PHDLFKOG_02378	0.0	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
PHDLFKOG_02379	7.22e-264	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PHDLFKOG_02380	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
PHDLFKOG_02381	4.23e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PHDLFKOG_02382	2.05e-134	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
PHDLFKOG_02383	7.16e-236	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
PHDLFKOG_02384	3.01e-163	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
PHDLFKOG_02385	1.28e-45	-	-	-	-	-	-	-	-
PHDLFKOG_02386	3.52e-175	tipA	-	-	K	-	-	-	TipAS antibiotic-recognition domain
PHDLFKOG_02387	3.99e-178	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PHDLFKOG_02388	5.43e-185	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHDLFKOG_02389	4.3e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHDLFKOG_02390	2.32e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PHDLFKOG_02391	3.3e-83	-	-	-	-	-	-	-	-
PHDLFKOG_02392	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_02393	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_02394	2.94e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
PHDLFKOG_02395	1.8e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHDLFKOG_02396	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PHDLFKOG_02397	6.28e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PHDLFKOG_02398	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
PHDLFKOG_02399	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PHDLFKOG_02400	3.86e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PHDLFKOG_02401	1.63e-297	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PHDLFKOG_02402	1.42e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
PHDLFKOG_02403	1.83e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
PHDLFKOG_02404	8.15e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PHDLFKOG_02405	5.63e-77	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PHDLFKOG_02406	3.7e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PHDLFKOG_02407	1.32e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PHDLFKOG_02408	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PHDLFKOG_02409	1.67e-66	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PHDLFKOG_02410	1.73e-77	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PHDLFKOG_02411	9.86e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PHDLFKOG_02412	4.53e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
PHDLFKOG_02413	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PHDLFKOG_02414	2.92e-153	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PHDLFKOG_02415	4.5e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PHDLFKOG_02416	5.26e-63	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PHDLFKOG_02417	2.07e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PHDLFKOG_02418	5.07e-62	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PHDLFKOG_02419	3.43e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
PHDLFKOG_02420	1.4e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PHDLFKOG_02421	1.09e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
PHDLFKOG_02422	1.26e-90	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
PHDLFKOG_02423	5.85e-139	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	C-terminal domain of 1-Cys peroxiredoxin
PHDLFKOG_02424	1.67e-250	-	-	-	K	-	-	-	WYL domain
PHDLFKOG_02425	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PHDLFKOG_02426	2.06e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PHDLFKOG_02427	3.18e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PHDLFKOG_02428	0.0	-	-	-	M	-	-	-	domain protein
PHDLFKOG_02429	3.06e-44	-	-	-	M	-	-	-	domain protein
PHDLFKOG_02430	2.84e-109	-	3.4.23.43	-	-	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	-
PHDLFKOG_02431	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHDLFKOG_02432	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PHDLFKOG_02433	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PHDLFKOG_02434	7.17e-104	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
PHDLFKOG_02444	1.13e-93	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
PHDLFKOG_02447	1.45e-46	-	-	-	-	-	-	-	-
PHDLFKOG_02448	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
PHDLFKOG_02449	1.12e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PHDLFKOG_02450	4.9e-207	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PHDLFKOG_02451	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PHDLFKOG_02452	2.04e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
PHDLFKOG_02453	9.66e-308	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PHDLFKOG_02454	8.3e-105	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
PHDLFKOG_02455	1.87e-84	divIC	-	-	D	ko:K05589,ko:K13052	-	ko00000,ko03036	cell cycle
PHDLFKOG_02456	2.33e-52	yabO	-	-	J	-	-	-	S4 domain protein
PHDLFKOG_02457	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
PHDLFKOG_02458	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PHDLFKOG_02459	1.05e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PHDLFKOG_02460	5.04e-232	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
PHDLFKOG_02461	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
PHDLFKOG_02462	2.6e-124	padR	-	-	K	-	-	-	Transcriptional regulator PadR-like family
PHDLFKOG_02463	0.0	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
PHDLFKOG_02464	3.35e-148	-	-	-	S	-	-	-	Flavodoxin-like fold
PHDLFKOG_02465	1.9e-154	-	-	-	S	-	-	-	(CBS) domain
PHDLFKOG_02466	1.69e-167	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
PHDLFKOG_02467	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PHDLFKOG_02468	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
PHDLFKOG_02469	1.33e-111	queT	-	-	S	-	-	-	QueT transporter
PHDLFKOG_02471	2.32e-82	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
PHDLFKOG_02472	5.46e-51	-	-	-	-	-	-	-	-
PHDLFKOG_02473	2.9e-276	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PHDLFKOG_02474	2.25e-83	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PHDLFKOG_02475	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PHDLFKOG_02476	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PHDLFKOG_02477	1.77e-189	-	-	-	-	-	-	-	-
PHDLFKOG_02478	1.11e-158	-	-	-	S	-	-	-	Tetratricopeptide repeat
PHDLFKOG_02479	4.49e-159	-	-	-	-	-	-	-	-
PHDLFKOG_02480	2.69e-95	-	-	-	-	-	-	-	-
PHDLFKOG_02481	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_02482	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_02483	3.24e-57	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
PHDLFKOG_02484	3.31e-300	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PHDLFKOG_02486	6.15e-06	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_02487	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PHDLFKOG_02488	2.23e-279	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
PHDLFKOG_02491	4.99e-194	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PHDLFKOG_02492	3.09e-103	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PHDLFKOG_02493	1.21e-103	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
PHDLFKOG_02494	2.07e-202	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
PHDLFKOG_02495	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
PHDLFKOG_02496	1.53e-107	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PHDLFKOG_02497	3.18e-239	-	-	-	S	-	-	-	DUF218 domain
PHDLFKOG_02498	1.4e-78	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PHDLFKOG_02499	1.16e-95	-	-	-	-	-	-	-	-
PHDLFKOG_02500	6.37e-67	nudA	-	-	S	-	-	-	ASCH
PHDLFKOG_02501	2.2e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHDLFKOG_02502	3.01e-295	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PHDLFKOG_02503	1.84e-281	ysaA	-	-	V	-	-	-	RDD family
PHDLFKOG_02504	1.01e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
PHDLFKOG_02505	1.84e-154	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_02506	1.38e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
PHDLFKOG_02507	1.57e-202	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
PHDLFKOG_02508	8.83e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PHDLFKOG_02509	4.13e-51	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
PHDLFKOG_02510	8e-197	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PHDLFKOG_02511	5.35e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PHDLFKOG_02512	7.18e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
PHDLFKOG_02513	7.89e-105	manR	2.7.1.194, 2.7.1.200, 2.7.1.202	-	G	ko:K02538,ko:K02768,ko:K02769,ko:K02770,ko:K02773,ko:K02806,ko:K02821,ko:K03491	ko00051,ko00052,ko00053,ko01100,ko01120,ko02060,map00051,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PHDLFKOG_02514	4.53e-238	lacD	4.1.2.40	-	G	ko:K01635	ko00052,ko01100,ko02024,map00052,map01100,map02024	ko00000,ko00001,ko01000	Belongs to the aldolase LacD family
PHDLFKOG_02515	3e-221	yqhA	-	-	G	-	-	-	Aldose 1-epimerase
PHDLFKOG_02516	1.23e-161	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
PHDLFKOG_02517	3.2e-212	-	-	-	T	-	-	-	GHKL domain
PHDLFKOG_02518	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PHDLFKOG_02519	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
PHDLFKOG_02520	3.93e-41	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional
PHDLFKOG_02521	3.43e-85	-	-	-	-	-	-	-	-
PHDLFKOG_02522	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PHDLFKOG_02523	8.68e-220	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
PHDLFKOG_02524	7.33e-188	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
PHDLFKOG_02525	4.46e-118	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
PHDLFKOG_02526	1.8e-217	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
PHDLFKOG_02527	3.59e-136	yiiE	-	-	S	-	-	-	Protein of unknown function (DUF1211)
PHDLFKOG_02528	3.42e-166	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	Sir2 family
PHDLFKOG_02530	6.25e-217	-	-	-	-	-	-	-	-
PHDLFKOG_02531	1.12e-125	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
PHDLFKOG_02532	5.16e-51	-	-	-	-	-	-	-	-
PHDLFKOG_02533	3.46e-219	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
PHDLFKOG_02534	1e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PHDLFKOG_02535	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PHDLFKOG_02536	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
PHDLFKOG_02537	8.29e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
PHDLFKOG_02538	2.94e-198	-	-	-	Q	-	-	-	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PHDLFKOG_02539	6.53e-118	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
PHDLFKOG_02540	1.3e-302	dinF	-	-	V	-	-	-	MatE
PHDLFKOG_02541	6.41e-141	-	-	-	S	ko:K06872	-	ko00000	TPM domain
PHDLFKOG_02542	4.87e-134	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
PHDLFKOG_02543	6.02e-246	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
PHDLFKOG_02544	8.37e-90	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_02545	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
PHDLFKOG_02546	2.58e-226	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_02547	0.0	choS	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PHDLFKOG_02548	0.0	-	-	-	L	-	-	-	DNA helicase
PHDLFKOG_02549	4.46e-189	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
PHDLFKOG_02550	2.03e-225	ydiA	-	-	P	ko:K11041	ko05150,map05150	ko00000,ko00001,ko02042	Voltage-dependent anion channel
PHDLFKOG_02551	5.4e-175	yadH	-	-	V	ko:K01992,ko:K09694	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
PHDLFKOG_02552	1.22e-170	cylA	-	-	V	ko:K01990,ko:K09695,ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_02553	9.8e-167	ydfF	-	-	K	-	-	-	Transcriptional
PHDLFKOG_02554	6.32e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
PHDLFKOG_02556	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
PHDLFKOG_02557	1.13e-138	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
PHDLFKOG_02558	4.69e-94	-	-	-	K	-	-	-	MarR family
PHDLFKOG_02559	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
PHDLFKOG_02560	9.22e-246	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
PHDLFKOG_02561	5.39e-183	-	-	-	S	-	-	-	hydrolase
PHDLFKOG_02562	3.33e-78	-	-	-	-	-	-	-	-
PHDLFKOG_02563	1.71e-17	-	-	-	-	-	-	-	-
PHDLFKOG_02564	2.65e-149	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
PHDLFKOG_02565	3.55e-163	gpmB	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
PHDLFKOG_02566	4.01e-194	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
PHDLFKOG_02567	1.38e-117	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PHDLFKOG_02568	2.17e-213	-	-	-	K	-	-	-	LysR substrate binding domain
PHDLFKOG_02569	4.76e-288	-	-	-	EK	-	-	-	Aminotransferase, class I
PHDLFKOG_02571	3.7e-60	-	-	-	-	-	-	-	-
PHDLFKOG_02572	5.18e-75	-	-	-	-	-	-	-	-
PHDLFKOG_02573	3.1e-254	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PHDLFKOG_02574	5.11e-149	ydfK	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
PHDLFKOG_02575	4.31e-115	-	-	-	-	-	-	-	-
PHDLFKOG_02577	0.0	fruC	2.7.1.202	-	GT	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_02578	1.12e-215	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
PHDLFKOG_02579	2.02e-168	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PHDLFKOG_02580	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PHDLFKOG_02581	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PHDLFKOG_02582	1.32e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PHDLFKOG_02583	2.69e-310	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
PHDLFKOG_02584	1.15e-203	-	-	-	K	-	-	-	LysR substrate binding domain
PHDLFKOG_02585	1.49e-97	-	-	-	-	-	-	-	-
PHDLFKOG_02586	1.95e-94	-	-	-	K	-	-	-	Transcriptional regulator
PHDLFKOG_02587	3.16e-312	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
PHDLFKOG_02588	4.99e-165	-	4.1.2.17	-	G	ko:K01628	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Class II Aldolase and Adducin N-terminal domain
PHDLFKOG_02590	0.0	pts36C	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_02591	6.21e-68	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_02592	1.7e-88	pts36A	2.7.1.200	-	G	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_02593	5.58e-156	rdrB	-	-	K	ko:K02444,ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
PHDLFKOG_02595	6.22e-211	rhaD	4.1.2.19	-	H	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PHDLFKOG_02596	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	L-rhamnose isomerase (RhaA)
PHDLFKOG_02597	4.22e-74	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
PHDLFKOG_02598	0.0	rhaB	2.7.1.5	-	F	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PHDLFKOG_02599	0.0	iolF	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
PHDLFKOG_02600	4.24e-247	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PHDLFKOG_02601	5.2e-276	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
PHDLFKOG_02602	4.69e-86	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
PHDLFKOG_02603	5.54e-156	-	-	-	-	-	-	-	-
PHDLFKOG_02604	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
PHDLFKOG_02605	0.0	-	-	-	M	-	-	-	Right handed beta helix region
PHDLFKOG_02606	6.74e-100	-	-	-	-	-	-	-	-
PHDLFKOG_02607	0.0	-	-	-	M	-	-	-	Heparinase II/III N-terminus
PHDLFKOG_02608	0.000638	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit
PHDLFKOG_02609	1.78e-86	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
PHDLFKOG_02610	7.09e-184	agaD	-	-	G	ko:K02747	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PHDLFKOG_02611	4.89e-172	-	-	-	G	ko:K02746	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PHDLFKOG_02612	9.9e-105	-	-	-	G	ko:K02745	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_02613	7.7e-258	ugl	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
PHDLFKOG_02614	1.8e-131	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
PHDLFKOG_02615	5.57e-141	-	-	-	K	-	-	-	Bacterial transcriptional regulator
PHDLFKOG_02616	2.55e-181	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PHDLFKOG_02617	2.15e-175	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PHDLFKOG_02618	6.85e-114	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
PHDLFKOG_02619	2.79e-192	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
PHDLFKOG_02620	2.58e-156	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PHDLFKOG_02621	0.0	hylB	4.2.2.1	PL8	N	ko:K01727	-	ko00000,ko01000	Polysaccharide lyase family 8, N terminal alpha-helical domain
PHDLFKOG_02622	1.76e-246	-	-	-	G	-	-	-	Melibiase
PHDLFKOG_02623	9.75e-54	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_02624	5.55e-83	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PHDLFKOG_02625	2.21e-79	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PHDLFKOG_02626	9.21e-30	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
PHDLFKOG_02627	8.53e-65	araR	-	-	K	ko:K02103	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
PHDLFKOG_02628	0.0	-	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
PHDLFKOG_02629	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
PHDLFKOG_02630	1.26e-133	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PHDLFKOG_02631	2.24e-93	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
PHDLFKOG_02632	6.58e-136	-	-	-	K	-	-	-	Transcriptional activator, Rgg GadR MutR family
PHDLFKOG_02633	3.33e-161	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PHDLFKOG_02634	2.22e-78	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHDLFKOG_02635	9.61e-15	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PHDLFKOG_02637	1.96e-177	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
PHDLFKOG_02638	3.41e-257	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
PHDLFKOG_02639	3.01e-275	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
PHDLFKOG_02640	1.94e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
PHDLFKOG_02641	2.89e-177	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
PHDLFKOG_02642	6.76e-75	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
PHDLFKOG_02643	1.23e-80	-	-	-	S	-	-	-	Glycine-rich SFCGS
PHDLFKOG_02644	1.33e-70	-	-	-	S	-	-	-	PRD domain
PHDLFKOG_02645	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
PHDLFKOG_02646	2.41e-158	-	-	-	H	-	-	-	Pfam:Transaldolase
PHDLFKOG_02647	1.74e-82	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
PHDLFKOG_02648	1.88e-252	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
PHDLFKOG_02649	1.43e-131	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
PHDLFKOG_02650	3.59e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
PHDLFKOG_02651	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
PHDLFKOG_02652	4.82e-184	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
PHDLFKOG_02653	5.59e-33	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
PHDLFKOG_02654	6.82e-40	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
PHDLFKOG_02655	1.83e-176	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PHDLFKOG_02656	3.56e-194	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
PHDLFKOG_02657	2.13e-212	sga	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
PHDLFKOG_02658	4.27e-176	-	-	-	K	-	-	-	DeoR C terminal sensor domain
PHDLFKOG_02659	1.51e-147	ulaD	4.1.1.85, 4.1.2.43	-	G	ko:K03078,ko:K08093	ko00030,ko00040,ko00053,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00040,map00053,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
PHDLFKOG_02660	3.93e-60	sgaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_02661	0.0	sgaT	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
PHDLFKOG_02662	1.64e-103	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PHDLFKOG_02663	3.47e-270	ulaG	-	-	S	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Beta-lactamase superfamily domain
PHDLFKOG_02664	0.0	prtP	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
PHDLFKOG_02665	5.44e-56	-	-	-	-	-	-	-	-
PHDLFKOG_02666	2.79e-199	-	-	-	GK	-	-	-	ROK family
PHDLFKOG_02667	3.03e-230	asnA2	3.5.1.1	-	E	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
PHDLFKOG_02668	1.68e-310	-	-	-	E	-	-	-	Peptidase family M20/M25/M40
PHDLFKOG_02669	2.04e-167	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
PHDLFKOG_02670	4.11e-273	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
PHDLFKOG_02671	5.24e-259	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
PHDLFKOG_02672	6.25e-117	-	-	-	K	ko:K03828	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
PHDLFKOG_02673	7.2e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
PHDLFKOG_02675	1.53e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
PHDLFKOG_02676	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
PHDLFKOG_02677	2.06e-170	-	-	-	F	-	-	-	NUDIX domain
PHDLFKOG_02678	2.68e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
PHDLFKOG_02679	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PHDLFKOG_02680	6.15e-170	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
PHDLFKOG_02681	2.81e-90	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PHDLFKOG_02682	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
PHDLFKOG_02683	6.89e-191	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_02684	2.51e-208	-	-	-	P	ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-type sugar transport systems, permease components
PHDLFKOG_02685	9.24e-269	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
PHDLFKOG_02686	7.56e-286	-	-	-	EGP	-	-	-	Transmembrane secretion effector
PHDLFKOG_02687	1.69e-186	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
PHDLFKOG_02688	5.13e-244	-	-	-	V	-	-	-	Beta-lactamase
PHDLFKOG_02689	1.47e-185	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PHDLFKOG_02690	5.24e-208	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
PHDLFKOG_02691	5.58e-104	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_02692	5.03e-192	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
PHDLFKOG_02693	3.98e-172	XK27_08455	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
PHDLFKOG_02695	7.17e-258	-	-	-	S	-	-	-	endonuclease exonuclease phosphatase family protein
PHDLFKOG_02696	7.62e-219	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
PHDLFKOG_02697	3.72e-202	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
PHDLFKOG_02698	1.23e-96	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
PHDLFKOG_02699	3.29e-182	-	-	-	Q	-	-	-	Methyltransferase
PHDLFKOG_02700	2.34e-65	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
PHDLFKOG_02701	8.78e-08	-	-	-	S	-	-	-	SpoVT / AbrB like domain
PHDLFKOG_02702	1.17e-178	-	-	-	V	-	-	-	ABC transporter transmembrane region
PHDLFKOG_02703	1.5e-74	-	-	-	-	-	-	-	-
PHDLFKOG_02704	2.09e-48	-	-	-	-	-	-	-	-
PHDLFKOG_02705	5.69e-140	-	-	-	S	-	-	-	alpha beta
PHDLFKOG_02706	8.86e-103	yfbM	-	-	K	-	-	-	FR47-like protein
PHDLFKOG_02707	6.78e-100	-	-	-	E	-	-	-	HAD-hyrolase-like
PHDLFKOG_02708	2.78e-170	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
PHDLFKOG_02709	9.36e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_02710	1.69e-158	-	-	-	-	-	-	-	-
PHDLFKOG_02711	1.33e-86	-	-	-	S	-	-	-	ASCH
PHDLFKOG_02712	1.18e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PHDLFKOG_02713	7.69e-254	ysdE	-	-	P	-	-	-	Citrate transporter
PHDLFKOG_02714	2.23e-134	-	-	-	-	-	-	-	-
PHDLFKOG_02715	5.64e-315	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
PHDLFKOG_02716	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
PHDLFKOG_02717	9.87e-200	-	-	-	-	-	-	-	-
PHDLFKOG_02718	0.0	bgaR	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
PHDLFKOG_02719	0.0	-	-	-	G	ko:K03292,ko:K16210	-	ko00000,ko02000	MFS/sugar transport protein
PHDLFKOG_02720	9.03e-245	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
PHDLFKOG_02721	6.11e-198	-	-	-	S	-	-	-	Glycosyl hydrolase family 115
PHDLFKOG_02722	0.0	cadA	-	-	P	-	-	-	P-type ATPase
PHDLFKOG_02723	4.09e-99	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
PHDLFKOG_02724	1.94e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PHDLFKOG_02725	1.99e-284	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
PHDLFKOG_02726	2.72e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
PHDLFKOG_02727	3.66e-183	yycI	-	-	S	-	-	-	YycH protein
PHDLFKOG_02728	0.0	yycH	-	-	S	-	-	-	YycH protein
PHDLFKOG_02729	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
PHDLFKOG_02730	5.24e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
PHDLFKOG_02731	1.1e-159	-	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Alpha/beta hydrolase family
PHDLFKOG_02732	0.0	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
PHDLFKOG_02733	3.99e-299	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
PHDLFKOG_02734	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
PHDLFKOG_02735	4.59e-271	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
PHDLFKOG_02736	3.7e-96	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
PHDLFKOG_02737	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHDLFKOG_02738	8.04e-168	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
PHDLFKOG_02739	2.7e-68	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_02740	2.91e-72	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
PHDLFKOG_02741	5.23e-140	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
PHDLFKOG_02742	4.22e-105	-	-	-	F	-	-	-	NUDIX domain
PHDLFKOG_02743	5.71e-116	-	-	-	S	-	-	-	AAA domain
PHDLFKOG_02744	2.24e-146	ycaC	-	-	Q	-	-	-	Isochorismatase family
PHDLFKOG_02745	3.98e-98	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_02746	8.74e-201	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
PHDLFKOG_02747	2.44e-269	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
PHDLFKOG_02748	7.35e-221	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
PHDLFKOG_02749	1.54e-84	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
PHDLFKOG_02750	7.33e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
PHDLFKOG_02751	6.18e-173	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
PHDLFKOG_02752	7.73e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
PHDLFKOG_02753	2.8e-278	-	-	-	EGP	-	-	-	Major facilitator Superfamily
PHDLFKOG_02754	7.25e-180	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
PHDLFKOG_02755	5.07e-203	-	-	-	K	-	-	-	sequence-specific DNA binding
PHDLFKOG_02759	6.67e-303	-	-	-	L	-	-	-	Integrase core domain
PHDLFKOG_02760	4.66e-176	-	-	-	L	-	-	-	Bacterial dnaA protein
PHDLFKOG_02761	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
PHDLFKOG_02763	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
PHDLFKOG_02764	1.89e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_02765	7.62e-53	-	-	-	-	-	-	-	-
PHDLFKOG_02766	3.33e-303	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
PHDLFKOG_02767	3.97e-23	-	-	-	-	-	-	-	-
PHDLFKOG_02768	1.89e-167	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
PHDLFKOG_02769	7.92e-76	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
PHDLFKOG_02770	9.87e-70	-	-	-	-	-	-	-	-
PHDLFKOG_02771	1.9e-104	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
PHDLFKOG_02772	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
PHDLFKOG_02773	8.69e-183	-	-	-	S	-	-	-	AAA ATPase domain
PHDLFKOG_02774	7.03e-213	-	-	-	G	-	-	-	Phosphotransferase enzyme family
PHDLFKOG_02775	7.69e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
PHDLFKOG_02776	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_02777	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
PHDLFKOG_02778	1.33e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
PHDLFKOG_02779	3.53e-134	-	-	-	S	ko:K06384	-	ko00000	Stage II sporulation protein M
PHDLFKOG_02780	2.85e-215	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
PHDLFKOG_02781	2.5e-172	-	-	-	S	-	-	-	Protein of unknown function DUF58
PHDLFKOG_02782	0.0	yebA	-	-	E	-	-	-	Transglutaminase/protease-like homologues
PHDLFKOG_02783	4.97e-272	-	-	-	M	-	-	-	Glycosyl transferases group 1
PHDLFKOG_02784	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
PHDLFKOG_02787	1.12e-250	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
PHDLFKOG_02788	1.04e-289	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	2-hydroxycarboxylate transporter family
PHDLFKOG_02789	0.0	dpiB	2.7.13.3	-	T	ko:K02476,ko:K11614	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Single cache domain 3
PHDLFKOG_02790	4.99e-154	malR	-	-	KT	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
PHDLFKOG_02791	1.43e-123	-	-	-	-	-	-	-	-
PHDLFKOG_02792	3.32e-150	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PHDLFKOG_02794	1.96e-192	-	-	-	I	-	-	-	NAD binding domain of 6-phosphogluconate dehydrogenase
PHDLFKOG_02795	3.93e-90	-	-	-	-	-	-	-	-
PHDLFKOG_02796	4.52e-169	-	-	-	F	-	-	-	Glutamine amidotransferase class-I
PHDLFKOG_02797	7.89e-216	-	-	-	O	-	-	-	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PHDLFKOG_02799	3.77e-217	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PHDLFKOG_02800	2.32e-233	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
PHDLFKOG_02801	9.48e-237	lipA	-	-	I	-	-	-	Carboxylesterase family
PHDLFKOG_02802	1.75e-275	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
PHDLFKOG_02803	5.35e-102	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PHDLFKOG_02804	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
PHDLFKOG_02805	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
PHDLFKOG_02806	2.92e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PHDLFKOG_02807	2.23e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
PHDLFKOG_02808	7.2e-60	-	-	-	-	-	-	-	-
PHDLFKOG_02809	1.29e-25	-	-	-	-	-	-	-	-
PHDLFKOG_02810	1.23e-175	-	-	-	-	-	-	-	-
PHDLFKOG_02811	2.08e-283	-	-	-	K	-	-	-	IrrE N-terminal-like domain
PHDLFKOG_02812	1.77e-194	hlyD3	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PHDLFKOG_02813	2.05e-162	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
PHDLFKOG_02814	3.88e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
PHDLFKOG_02815	4.41e-113	-	-	-	C	-	-	-	nadph quinone reductase
PHDLFKOG_02816	3.85e-94	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
PHDLFKOG_02817	8.61e-39	-	-	-	-	-	-	-	-
PHDLFKOG_02818	4.23e-237	-	-	-	-	-	-	-	-
PHDLFKOG_02819	0.0	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
PHDLFKOG_02820	8.37e-308	-	-	-	M	-	-	-	Leucine rich repeats (6 copies)
PHDLFKOG_02821	1.58e-285	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
PHDLFKOG_02822	5.63e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
PHDLFKOG_02823	9e-191	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
PHDLFKOG_02826	1.22e-76	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
PHDLFKOG_02827	4.1e-251	ypjH	-	-	C	ko:K08317	-	ko00000,ko01000	dehydrogenase
PHDLFKOG_02829	2.84e-284	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
PHDLFKOG_02830	1.8e-105	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
PHDLFKOG_02831	3.65e-173	-	-	-	S	-	-	-	Putative threonine/serine exporter
PHDLFKOG_02833	6.61e-41	-	-	-	-	-	-	-	-
PHDLFKOG_02834	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
PHDLFKOG_02835	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PHDLFKOG_02836	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PHDLFKOG_02837	2.86e-10	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PHDLFKOG_02838	3.01e-177	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
PHDLFKOG_02839	8.28e-182	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PHDLFKOG_02840	1.56e-78	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PHDLFKOG_02843	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family