ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HEPIINGN_00002 1.15e-31 - - - - - - - -
HEPIINGN_00003 0.0 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HEPIINGN_00004 3.2e-44 - - - - - - - -
HEPIINGN_00005 7.09e-127 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
HEPIINGN_00006 0.0 - - - S - - - ABC transporter substrate-binding protein PnrA-like
HEPIINGN_00007 1.74e-140 - - - S - - - Protein of unknown function (DUF1643)
HEPIINGN_00008 6.95e-83 - - - I - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00011 6.08e-237 - - - - - - - -
HEPIINGN_00013 0.0 - - - - - - - -
HEPIINGN_00016 1.52e-238 - - - - - - - -
HEPIINGN_00017 3.08e-130 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HEPIINGN_00018 0.0 - - - - - - - -
HEPIINGN_00019 0.0 - - - S - - - Terminase-like family
HEPIINGN_00021 6.45e-226 - - - G ko:K10540 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG COG1879 ABC-type sugar transport system, periplasmic component
HEPIINGN_00022 0.0 mglA 3.6.3.17 - G ko:K10542 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC-type sugar transport system, ATPase component
HEPIINGN_00023 2.12e-227 mglC - - G ko:K10541 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00025 0.0 - - - S ko:K06972 - ko00000,ko01000,ko01002 Peptidase M16C associated
HEPIINGN_00026 1.22e-307 pbuG - - S ko:K06901 - ko00000,ko02000 xanthine uracil permease family protein K06901
HEPIINGN_00027 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HEPIINGN_00028 1.02e-169 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_00029 0.0 - - CE1 Q ko:K03932 - ko00000 Esterase PHB depolymerase
HEPIINGN_00030 1.1e-276 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribose-phosphate pyrophosphokinase family
HEPIINGN_00031 1.75e-275 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEPIINGN_00032 1.15e-278 - - - T - - - diguanylate cyclase
HEPIINGN_00033 2.31e-155 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEPIINGN_00035 1.61e-111 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00036 0.0 ispH 1.17.7.4 - IJM ko:K02945,ko:K03527 ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010 br01610,ko00000,ko00001,ko00002,ko01000,ko03011 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HEPIINGN_00037 2.01e-147 plsC_1 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HEPIINGN_00038 6.79e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HEPIINGN_00039 2.18e-306 - - - S ko:K07007 - ko00000 Flavoprotein family
HEPIINGN_00040 3.57e-151 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_00041 3.74e-240 - - - G - - - Major Facilitator Superfamily
HEPIINGN_00042 7.56e-150 - - - M - - - Peptidase, M23 family
HEPIINGN_00043 1.48e-295 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HEPIINGN_00044 0.0 - - - M - - - Belongs to the glycosyl hydrolase 28 family
HEPIINGN_00045 3.27e-172 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_00046 1.99e-210 - - - P ko:K10194 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEPIINGN_00047 3.8e-223 - - - P ko:K02025,ko:K10193 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate ABC transporter membrane protein 1 CUT1 family
HEPIINGN_00048 0.0 - - - G ko:K02027,ko:K10192 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEPIINGN_00049 1.36e-144 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HEPIINGN_00050 4.69e-151 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEPIINGN_00051 5.89e-161 tepA 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Psort location Cytoplasmic, score
HEPIINGN_00052 0.0 spoIIIE - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEPIINGN_00053 0.0 - - - C - - - UPF0313 protein
HEPIINGN_00054 6.52e-219 - - - J ko:K02238 - ko00000,ko00002,ko02044 Metallo-beta-lactamase domain protein
HEPIINGN_00055 3.59e-97 - - - - - - - -
HEPIINGN_00056 0.0 gltA2 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 citrate synthase
HEPIINGN_00057 1.63e-95 - - - K - - - Transcriptional regulator, BlaI MecI CopY family
HEPIINGN_00058 6.21e-266 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HEPIINGN_00059 4.3e-277 pdxB 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
HEPIINGN_00060 2.4e-208 - - - S ko:K03453 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_00061 4.9e-297 - - - L - - - Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEPIINGN_00062 0.0 - 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 Putative ATP-dependent Lon protease
HEPIINGN_00063 0.0 - - - S - - - TIGR02687 family
HEPIINGN_00065 0.0 - - - L - - - restriction
HEPIINGN_00067 0.0 - - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HEPIINGN_00068 3.96e-126 - - - S - - - Domain of unknown function (DUF1788)
HEPIINGN_00069 1.2e-145 - - - S - - - Putative inner membrane protein (DUF1819)
HEPIINGN_00070 8.78e-238 - - - S - - - Fic/DOC family
HEPIINGN_00072 1.88e-224 - - - S - - - Domain of unknown function (DUF932)
HEPIINGN_00074 1.95e-221 - - - L - - - YqaJ viral recombinase family
HEPIINGN_00075 1.47e-154 - - - S - - - Protein of unknown function (DUF1071)
HEPIINGN_00076 0.0 - - - S - - - Predicted AAA-ATPase
HEPIINGN_00077 3.11e-73 - - - L - - - Domain of unknown function (DUF3846)
HEPIINGN_00078 2.06e-82 - - - - - - - -
HEPIINGN_00079 1.62e-172 - - - L - - - Resolvase, N terminal domain
HEPIINGN_00083 1.22e-128 - - - T ko:K06883 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEPIINGN_00084 0.0 - - - T ko:K06883 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HEPIINGN_00086 1.99e-238 - - - K - - - WYL domain
HEPIINGN_00087 2.75e-72 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_00088 8.04e-296 - - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Peptidase family M41
HEPIINGN_00091 3.94e-41 - - - K - - - Helix-turn-helix domain
HEPIINGN_00096 1.01e-256 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_00097 2.31e-154 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_00098 6.83e-101 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00099 1.76e-280 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00100 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00105 2.53e-147 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Psort location Cytoplasmic, score
HEPIINGN_00106 6.09e-26 - - - - - - - -
HEPIINGN_00107 1.57e-172 tsaA - - S - - - Methyltransferase, YaeB family
HEPIINGN_00108 4.03e-207 - - - K - - - LysR substrate binding domain
HEPIINGN_00109 1.6e-269 - - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEPIINGN_00110 1.78e-166 - - - K - - - transcriptional regulator AraC family
HEPIINGN_00111 1.83e-295 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00112 3.98e-230 scrK 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00113 4.14e-121 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HEPIINGN_00114 4.32e-47 - - - - - - - -
HEPIINGN_00115 6.5e-249 - - - T - - - diguanylate cyclase
HEPIINGN_00116 4.34e-269 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEPIINGN_00117 1.17e-220 - - - GK - - - ROK family
HEPIINGN_00119 9.2e-100 - - - - - - - -
HEPIINGN_00120 1.07e-303 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEPIINGN_00121 2.59e-102 - - - S - - - Pfam:DUF3816
HEPIINGN_00122 0.0 pz-A - - E - - - Peptidase family M3
HEPIINGN_00125 4.31e-195 - - - S - - - Psort location
HEPIINGN_00126 4.69e-158 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00127 3.86e-119 - - - - - - - -
HEPIINGN_00128 3.92e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_00129 3.15e-184 birA 6.3.4.15 - HK ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEPIINGN_00130 6.23e-192 rnfB - - C ko:K03616 - ko00000 electron transport complex, RnfABCDGE type, B subunit
HEPIINGN_00131 4.14e-139 rnfA - - C ko:K03617 - ko00000 Part of a membrane complex involved in electron transport
HEPIINGN_00132 1.23e-150 rnfE - - C ko:K03613 - ko00000 Part of a membrane complex involved in electron transport
HEPIINGN_00133 1.54e-119 rnfG - - C ko:K03612 - ko00000 Part of a membrane complex involved in electron transport
HEPIINGN_00134 1.47e-216 rnfD - - C ko:K03614 - ko00000 Part of a membrane complex involved in electron transport
HEPIINGN_00135 3.37e-311 rnfC - - C ko:K03615 - ko00000 Part of a membrane complex involved in electron transport
HEPIINGN_00140 4.68e-136 KatE - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00141 0.0 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase, group 2 family protein
HEPIINGN_00142 5.44e-176 - - - GM ko:K01990 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_00143 5.05e-189 pyrL - - GM ko:K01992,ko:K09690 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HEPIINGN_00144 5.62e-142 rfbC 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HEPIINGN_00145 1.62e-310 dacB_3 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEPIINGN_00146 7.84e-133 spoVFB - - H ko:K06411 - ko00000 Dipicolinic acid synthetase, B subunit
HEPIINGN_00147 5.67e-166 spoVFA - - EH ko:K06410 - ko00000 dipicolinic acid synthetase, A subunit
HEPIINGN_00148 0.0 - - - T - - - His Kinase A (phosphoacceptor) domain
HEPIINGN_00149 3.36e-131 fliY1 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEPIINGN_00150 0.0 - - - T ko:K07814 - ko00000,ko02022 Response regulator containing a CheY-like receiver domain and an HD-GYP domain
HEPIINGN_00152 3.61e-304 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEPIINGN_00153 0.0 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00154 1.85e-251 livK - - E ko:K01999 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type branched-chain amino acid transport systems periplasmic component
HEPIINGN_00155 3.12e-193 livH - - E ko:K01997 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEPIINGN_00156 1.43e-230 livM - - E ko:K01998 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEPIINGN_00157 4.52e-200 livG - - E ko:K01995 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type branched-chain amino acid transport systems ATPase component
HEPIINGN_00158 5.4e-162 livF - - E ko:K01996 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEPIINGN_00159 2.46e-249 asnA 6.3.1.1 - E ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate-ammonia ligase
HEPIINGN_00160 1e-218 - - - S - - - Uncharacterised protein, DegV family COG1307
HEPIINGN_00161 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEPIINGN_00162 2.48e-39 ynzC - - S - - - Bacterial protein of unknown function (DUF896)
HEPIINGN_00163 2.2e-143 queH 1.17.99.6 - C ko:K09765 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HEPIINGN_00164 4.97e-252 - - - G - - - Transporter, major facilitator family protein
HEPIINGN_00165 1.77e-281 - - - Q - - - D-alanine [D-alanyl carrier protein] ligase activity
HEPIINGN_00166 7.32e-46 - - - IQ ko:K02078 - ko00000,ko00001 Acyl carrier protein
HEPIINGN_00167 0.0 - 6.2.1.3 - I ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 Psort location Cytoplasmic, score
HEPIINGN_00168 1.05e-274 - - - G - - - Acyltransferase family
HEPIINGN_00170 0.0 - - - M - - - Glycosyl-transferase family 4
HEPIINGN_00171 1.39e-234 mprF - - S ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEPIINGN_00173 0.0 pflB 2.3.1.54 - C ko:K00656 ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120 ko00000,ko00001,ko01000 TIGRFAM formate acetyltransferase
HEPIINGN_00174 2.32e-183 pflA 1.97.1.4 - C ko:K04069 - ko00000,ko01000 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEPIINGN_00175 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEPIINGN_00176 3.3e-302 adh - - C - - - belongs to the iron- containing alcohol dehydrogenase family
HEPIINGN_00180 1.34e-109 - - - K - - - Transcriptional regulator
HEPIINGN_00181 2.42e-70 - - - P - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00182 6.81e-111 - - - - - - - -
HEPIINGN_00183 2.49e-297 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins
HEPIINGN_00184 2.76e-104 nifU - - C ko:K04488 - ko00000 Fe-S iron-sulfur cluster assembly protein, NifU family
HEPIINGN_00185 0.0 - - - S - - - AAA domain (dynein-related subfamily)
HEPIINGN_00186 0.0 - - - S - - - VWA-like domain (DUF2201)
HEPIINGN_00187 1.62e-255 - - - S - - - Leucine rich repeats (6 copies)
HEPIINGN_00188 1.31e-210 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 periplasmic binding protein
HEPIINGN_00189 1.55e-172 - 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HEPIINGN_00190 1.66e-203 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEPIINGN_00191 3.43e-182 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEPIINGN_00192 4.21e-111 - - - K ko:K07736 - ko00000,ko03000 CarD-like/TRCF domain
HEPIINGN_00193 8.92e-317 - - - V - - - MATE efflux family protein
HEPIINGN_00194 5.28e-191 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00195 1.44e-99 - - - S - - - Protein of unknown function (DUF3801)
HEPIINGN_00196 7.16e-121 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_00197 3.56e-256 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00198 1.28e-80 - - - S - - - Transposon-encoded protein TnpV
HEPIINGN_00199 1.11e-51 - - - - - - - -
HEPIINGN_00202 2.83e-124 - - - L - - - Resolvase, N terminal domain
HEPIINGN_00203 5.84e-107 - - - V - - - Type II restriction enzyme, methylase subunits
HEPIINGN_00204 7.55e-277 - - - L - - - Eco57I restriction-modification methylase
HEPIINGN_00205 0.0 - - - V - - - T5orf172
HEPIINGN_00206 1.78e-32 - - - - - - - -
HEPIINGN_00208 6.38e-146 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00209 0.0 - - - D - - - MobA MobL family protein
HEPIINGN_00210 7.53e-225 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_00211 3.51e-88 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
HEPIINGN_00212 8.1e-81 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00213 3.8e-144 - - - V ko:K01990 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 9.49
HEPIINGN_00214 1.13e-159 - - - CP - - - ABC-2 family transporter protein
HEPIINGN_00215 5.37e-164 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_00216 3.58e-58 - - - - - - - -
HEPIINGN_00217 0.0 - - - M - - - NlpC P60 family protein
HEPIINGN_00218 7.74e-47 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00219 5.51e-165 - - - S - - - Domain of unknown function (DUF4366)
HEPIINGN_00220 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_00221 0.0 - - - L - - - YodL-like
HEPIINGN_00222 3.71e-209 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00223 5.79e-39 - - - S - - - Putative tranposon-transfer assisting protein
HEPIINGN_00224 1.64e-207 - - - K - - - BRO family, N-terminal domain
HEPIINGN_00225 1.67e-307 - - - U - - - Relaxase mobilization nuclease domain protein
HEPIINGN_00226 2.8e-70 - - - S - - - Bacterial mobilisation protein (MobC)
HEPIINGN_00227 6.76e-84 - - - K - - - Helix-turn-helix
HEPIINGN_00228 1.98e-165 - - - K - - - COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEPIINGN_00229 2.11e-228 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEPIINGN_00230 2.43e-135 - - - V ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_00231 1.6e-151 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEPIINGN_00232 0.0 - - - MV - - - Efflux ABC transporter, permease protein
HEPIINGN_00233 2.9e-95 - - - K - - - Sigma-70, region 4
HEPIINGN_00234 1.46e-50 - - - S - - - Helix-turn-helix domain
HEPIINGN_00235 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00238 7.27e-216 tig - - D ko:K03545 - ko00000 peptidyl-prolyl cis-trans isomerase activity
HEPIINGN_00239 2.23e-157 - - - S - - - SNARE associated Golgi protein
HEPIINGN_00240 1.48e-251 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00241 2.61e-196 - - - S - - - Cof-like hydrolase
HEPIINGN_00242 0.0 phoA 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HEPIINGN_00243 5.15e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEPIINGN_00244 3.94e-228 - - - - - - - -
HEPIINGN_00245 3.2e-49 - - - S - - - Protein of unknown function (DUF1653)
HEPIINGN_00246 0.0 - - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEPIINGN_00247 1.39e-252 - - - S - - - Sel1-like repeats.
HEPIINGN_00248 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEPIINGN_00249 0.0 - - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC-type multidrug transport system ATPase and permease
HEPIINGN_00250 4.74e-44 - - - U ko:K03117 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 mttA/Hcf106 family
HEPIINGN_00251 2.4e-33 tatA - - U ko:K03116,ko:K03117,ko:K03425 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 protein secretion
HEPIINGN_00252 5.51e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HEPIINGN_00253 0.0 malP_1 2.4.1.1 GT35 F ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEPIINGN_00254 8.86e-210 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_00255 6.01e-54 - - - P - - - mercury ion transmembrane transporter activity
HEPIINGN_00256 4.37e-151 lrgB - - M - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00257 1.01e-44 lrgA - - S ko:K06518 - ko00000,ko02000 LrgA family
HEPIINGN_00258 1.29e-105 - - - L - - - Nuclease-related domain
HEPIINGN_00259 1.49e-97 - - - K - - - Transcriptional regulator
HEPIINGN_00260 4.6e-220 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEPIINGN_00261 3.68e-229 - - - H - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEPIINGN_00262 7.23e-51 yrzL - - S - - - Belongs to the UPF0297 family
HEPIINGN_00263 2.34e-88 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEPIINGN_00264 1.25e-74 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_00265 2.29e-308 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEPIINGN_00266 1.56e-148 fabG5 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Oxidoreductase, short chain dehydrogenase reductase family protein
HEPIINGN_00267 7.6e-118 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEPIINGN_00268 1.14e-83 - - - S ko:K07052 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_00269 7.2e-200 - - - S - - - EDD domain protein, DegV family
HEPIINGN_00270 7.94e-174 yfcA - - S ko:K07090 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00271 2.74e-242 - 3.4.13.19 - E ko:K01273 - ko00000,ko00537,ko01000,ko01002,ko04147 Renal dipeptidase family protein
HEPIINGN_00272 0.0 - 2.7.11.1 - KL ko:K08282 - ko00000,ko01000 SNF2 family
HEPIINGN_00273 7.32e-269 - - - T - - - diguanylate cyclase
HEPIINGN_00274 1.14e-83 - - - K - - - iron dependent repressor
HEPIINGN_00275 5.82e-124 fumB 4.2.1.2 - C ko:K01678 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Hydrolyase, tartrate beta subunit fumarate domain protein, Fe-S type
HEPIINGN_00276 3.87e-201 fumA 4.2.1.2 - C ko:K01677 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Hydrolyase, tartrate alpha subunit fumarate domain protein, Fe-S type
HEPIINGN_00277 1.84e-280 - 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HEPIINGN_00278 1.03e-179 tig_1 - - O ko:K03545 - ko00000 peptidylprolyl isomerase
HEPIINGN_00279 1.58e-133 pgsA 2.7.8.41, 2.7.8.5 - I ko:K00995,ko:K08744 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEPIINGN_00280 0.0 rimO 2.8.4.4 - J ko:K14441 - ko00000,ko01000,ko03009 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HEPIINGN_00281 4.15e-105 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HEPIINGN_00282 5.35e-269 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEPIINGN_00283 3.77e-221 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEPIINGN_00284 2.68e-226 prmC - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00285 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEPIINGN_00286 9.68e-159 - - - K - - - response regulator receiver
HEPIINGN_00287 4.8e-309 - - - S - - - Tetratricopeptide repeat
HEPIINGN_00288 2.75e-72 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HEPIINGN_00289 3.11e-222 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEPIINGN_00290 4.36e-136 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEPIINGN_00291 1.25e-88 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEPIINGN_00292 3.34e-80 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEPIINGN_00293 7.03e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HEPIINGN_00294 6.09e-53 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEPIINGN_00295 1.82e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HEPIINGN_00296 5.7e-146 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEPIINGN_00297 5.58e-289 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEPIINGN_00298 2.45e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEPIINGN_00299 1.83e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 ribosomal protein
HEPIINGN_00300 6.22e-108 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEPIINGN_00301 3.26e-76 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEPIINGN_00302 1.05e-130 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEPIINGN_00303 2.77e-90 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEPIINGN_00305 1.67e-38 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEPIINGN_00306 6.11e-129 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEPIINGN_00307 6.77e-71 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEPIINGN_00308 4.58e-82 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEPIINGN_00309 2.02e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEPIINGN_00310 9.04e-34 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HEPIINGN_00311 1.42e-101 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEPIINGN_00312 1.98e-167 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEPIINGN_00313 1.01e-73 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEPIINGN_00314 2.9e-60 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEPIINGN_00315 1.3e-202 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEPIINGN_00316 1.26e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEPIINGN_00317 3.72e-145 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HEPIINGN_00318 6.65e-145 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEPIINGN_00319 6.56e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HEPIINGN_00320 0.0 FbpA - - K - - - Fibronectin-binding protein
HEPIINGN_00321 1e-172 - - - S - - - dinuclear metal center protein, YbgI
HEPIINGN_00322 2.6e-136 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HEPIINGN_00323 4.95e-57 - - - C - - - Hydrid cluster protein-associated redox disulfide domain
HEPIINGN_00324 6.57e-195 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00325 3.27e-150 - - - K - - - Belongs to the P(II) protein family
HEPIINGN_00326 7.02e-300 - - - T - - - Protein of unknown function (DUF1538)
HEPIINGN_00327 0.0 - - - S - - - Polysaccharide biosynthesis protein
HEPIINGN_00328 3.81e-129 - - - S ko:K07043 - ko00000 Protein of unknown function DUF45
HEPIINGN_00329 2.52e-210 - - - EG - - - EamA-like transporter family
HEPIINGN_00330 4.68e-123 - - - - - - - -
HEPIINGN_00331 3.18e-250 - - - M - - - lipoprotein YddW precursor K01189
HEPIINGN_00335 1.27e-228 - - - L - - - Phage integrase family
HEPIINGN_00337 1.61e-70 - - - T ko:K03497,ko:K07171 - ko00000,ko01000,ko02048,ko03000,ko03036,ko04812 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_00338 8.75e-199 - - - K - - - DNA binding
HEPIINGN_00339 6.68e-165 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_00341 1.4e-47 - - - K - - - PFAM helix-turn-helix domain protein
HEPIINGN_00342 7.04e-10 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEPIINGN_00343 1.14e-164 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00344 3.53e-27 nagE 2.7.1.193 - G ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00346 3.54e-128 - - - S - - - Haloacid dehalogenase-like hydrolase
HEPIINGN_00347 7.39e-188 agaD - - G ko:K02747 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00348 4.35e-174 agaC - - G ko:K02746 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko02000 PTS system sorbose-specific iic component
HEPIINGN_00349 2.68e-105 - 2.7.1.191 - G ko:K02745,ko:K02794 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system sorbose subfamily IIB component
HEPIINGN_00350 2.09e-254 - - - K - - - transcriptional regulator (AraC family)
HEPIINGN_00351 1.18e-142 - - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase NAD-binding domain protein
HEPIINGN_00352 2.12e-191 - 4.1.2.13, 4.1.2.40 - G ko:K01624,ko:K08302 ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 COG COG0191 Fructose tagatose bisphosphate aldolase
HEPIINGN_00353 6.34e-49 - - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase, YajC subunit
HEPIINGN_00354 3.6e-91 - - - G ko:K02744 ko00052,ko02060,map00052,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HEPIINGN_00355 7.68e-274 agaS 2.6.1.16 - M ko:K00820,ko:K02082 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 sugar isomerase, AgaS family
HEPIINGN_00356 3.27e-257 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEPIINGN_00357 3.35e-305 - - - G ko:K16371 ko00052,ko01100,map00052,map01100 ko00000,ko00001 Tagatose 6 phosphate kinase
HEPIINGN_00358 6.8e-42 - - - G ko:K11189 - ko00000,ko02000 phosphocarrier, HPr family
HEPIINGN_00361 6.59e-69 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HEPIINGN_00362 1.03e-101 - - - - - - - -
HEPIINGN_00363 0.0 - - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HEPIINGN_00364 5e-37 - - - - - - - -
HEPIINGN_00365 1e-292 - 3.6.4.12 - L ko:K03658 - ko00000,ko01000,ko03400 UvrD/REP helicase N-terminal domain
HEPIINGN_00366 1.66e-11 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00367 3.47e-15 - - - K - - - DNA-binding helix-turn-helix protein
HEPIINGN_00370 5.55e-300 - - - U - - - Relaxase mobilization nuclease domain protein
HEPIINGN_00373 9e-63 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00374 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00376 1.01e-44 - - - - - - - -
HEPIINGN_00377 3.81e-24 - - - - - - - -
HEPIINGN_00378 9.97e-36 - - - S - - - Putative tranposon-transfer assisting protein
HEPIINGN_00379 1.77e-114 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00380 1.16e-210 - - - D - - - Psort location Cytoplasmic, score
HEPIINGN_00381 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_00382 4.74e-131 - - - S - - - Domain of unknown function (DUF4366)
HEPIINGN_00384 0.0 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HEPIINGN_00385 0.0 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_00386 1.73e-74 - - - S - - - PrgI family protein
HEPIINGN_00387 4.13e-196 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00388 2.36e-38 - - - S - - - Maff2 family
HEPIINGN_00389 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_00390 6.22e-60 - - - S - - - Protein of unknown function (DUF3801)
HEPIINGN_00391 5.85e-91 - - - S - - - Domain of unknown function (DUF3846)
HEPIINGN_00393 4.96e-185 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEPIINGN_00394 3.97e-160 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HEPIINGN_00395 9.08e-200 - - - S - - - Replication initiator protein A
HEPIINGN_00396 6.44e-213 - - - S - - - Patatin-like phospholipase
HEPIINGN_00397 0.0 - - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC-type multidrug transport system, ATPase and permease components
HEPIINGN_00398 7.66e-163 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEPIINGN_00399 5.39e-130 - - - S - - - Belongs to the UPF0340 family
HEPIINGN_00400 6.4e-298 - 3.1.1.17 - G ko:K01053,ko:K02352 ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220 ko00000,ko00001,ko00002,ko01000,ko04147 gluconolactonase activity
HEPIINGN_00401 0.0 - 2.3.1.79 - M ko:K00661 - ko00000,ko01000 Bacterial transferase hexapeptide (six repeats)
HEPIINGN_00402 3.29e-163 resD - - K ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
HEPIINGN_00403 0.0 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEPIINGN_00405 3.18e-237 - 3.1.1.11 - G ko:K01051 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Pectinesterase
HEPIINGN_00406 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HEPIINGN_00407 1.06e-66 - - - S - - - Domain of unknown function (DUF4160)
HEPIINGN_00408 5.13e-64 - - - - - - - -
HEPIINGN_00409 0.0 gltX 6.1.1.17, 6.1.1.24 - J ko:K01885,ko:K09698 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEPIINGN_00410 9.25e-103 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00411 7.68e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HEPIINGN_00412 0.0 - - - O ko:K03697 - ko00000,ko03110 ATPase family associated with various cellular activities (AAA)
HEPIINGN_00413 9.86e-130 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00414 6.68e-282 - - - - - - - -
HEPIINGN_00415 3.97e-179 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEPIINGN_00416 2.12e-185 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEPIINGN_00417 4.58e-217 cbiO - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEPIINGN_00418 8.39e-196 - - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEPIINGN_00419 4.81e-226 rlmL_1 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 S-adenosylmethionine-dependent methyltransferase
HEPIINGN_00420 2.67e-251 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEPIINGN_00421 1.19e-130 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEPIINGN_00422 1.2e-116 ruvC 3.1.22.4 - L ko:K01159 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HEPIINGN_00424 4.38e-35 - - - - - - - -
HEPIINGN_00425 8.4e-93 - - - S ko:K06934 - ko00000 Domain of unknown function (DUF296)
HEPIINGN_00426 0.0 - - - I - - - Lipase (class 3)
HEPIINGN_00427 2.75e-213 - - - K - - - LysR substrate binding domain protein
HEPIINGN_00428 2.91e-176 - - - S - - - TraX protein
HEPIINGN_00431 7.52e-151 - 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 DNA-binding helix-turn-helix protein
HEPIINGN_00432 0.0 - - - L - - - DNA modification repair radical SAM protein
HEPIINGN_00433 1.71e-197 - - - L - - - DNA metabolism protein
HEPIINGN_00434 4.85e-58 spiA - - K ko:K18831 - ko00000,ko02048,ko03000 sequence-specific DNA binding
HEPIINGN_00435 2.3e-115 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEPIINGN_00436 0.0 - - - S ko:K07137 - ko00000 Oxidoreductase
HEPIINGN_00437 2.73e-149 - - - S - - - Short repeat of unknown function (DUF308)
HEPIINGN_00438 7.52e-289 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00439 3.33e-140 - - - F - - - Cytidylate kinase-like family
HEPIINGN_00440 0.0 - - - - - - - -
HEPIINGN_00441 5.06e-197 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00442 8.99e-168 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Phosphate acyltransferases
HEPIINGN_00443 1.15e-183 - - - - - - - -
HEPIINGN_00445 6.01e-246 pheA 4.2.1.51, 5.4.99.5 - E ko:K04518,ko:K14170 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HEPIINGN_00446 2.98e-246 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HEPIINGN_00447 6.97e-264 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HEPIINGN_00448 2.7e-295 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HEPIINGN_00449 1.63e-113 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HEPIINGN_00450 4.06e-244 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 synthase
HEPIINGN_00451 1.03e-301 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HEPIINGN_00452 1.65e-206 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HEPIINGN_00453 8.08e-234 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_00454 1.42e-236 - - - S - - - Protein of unknown function DUF89
HEPIINGN_00455 2.23e-165 dam 2.1.1.72 - L ko:K06223 ko03430,map03430 ko00000,ko00001,ko01000,ko02048,ko03032,ko03400 site-specific DNA-methyltransferase (Adenine-specific)
HEPIINGN_00456 0.0 - - - O - - - ATPase, AAA family
HEPIINGN_00457 1.86e-54 - - - - - - - -
HEPIINGN_00458 1.03e-237 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00459 2.17e-208 cobW - - S - - - CobW/HypB/UreG, nucleotide-binding domain
HEPIINGN_00460 0.0 pepQ 3.4.11.9 - E ko:K01262 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEPIINGN_00461 1.88e-122 rcoM2 - - KT ko:K02477,ko:K21696 - ko00000,ko02022,ko03000 phosphorelay signal transduction system
HEPIINGN_00462 3.29e-235 - - - M - - - Glycosyltransferase, group 2 family protein
HEPIINGN_00463 4.02e-158 - - - S - - - IA, variant 3
HEPIINGN_00464 9.69e-273 - - - S ko:K07001 - ko00000 Psort location Cytoplasmic, score 8.96
HEPIINGN_00465 0.0 - 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEPIINGN_00466 1.56e-175 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEPIINGN_00467 9.51e-210 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HEPIINGN_00468 6.13e-142 - - - K - - - Acetyltransferase (GNAT) domain
HEPIINGN_00469 6.88e-257 - - - U - - - domain, Protein
HEPIINGN_00470 7.67e-152 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_00471 3.02e-69 - 4.2.1.9 - EG ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HEPIINGN_00472 1.2e-300 - - - EG ko:K03299,ko:K06155,ko:K06156,ko:K06157 - ko00000,ko02000 Gluconate
HEPIINGN_00473 3.26e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEPIINGN_00474 5.95e-121 - - - K - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00475 0.0 pckA 4.1.1.49 - H ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HEPIINGN_00476 7.16e-139 - - - S - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_00478 1.74e-224 oppF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HEPIINGN_00479 7.23e-263 - - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Oligopeptide/dipeptide transporter, C-terminal region
HEPIINGN_00480 3.3e-228 oppC - - P ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 N-terminal TM domain of oligopeptide transport permease C
HEPIINGN_00481 1.15e-193 oppB - - EP ko:K02033,ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEPIINGN_00482 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HEPIINGN_00483 1.39e-228 tktB 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, pyridine binding domain protein
HEPIINGN_00484 4.04e-205 tktA 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transketolase, thiamine diphosphate binding domain
HEPIINGN_00485 4.27e-114 - - - S ko:K16788 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_00486 9.84e-155 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEPIINGN_00487 0.0 - 3.1.3.48 - K ko:K01104 - ko00000,ko01000 Pfam:Y_phosphatase3C
HEPIINGN_00488 0.0 pulA 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HEPIINGN_00490 2.08e-278 - 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain
HEPIINGN_00491 2.53e-206 - - - JK - - - Acetyltransferase (GNAT) family
HEPIINGN_00492 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEPIINGN_00493 5.52e-241 - - - C ko:K18471 ko00640,map00640 ko00000,ko00001,ko01000 Aldo/keto reductase family
HEPIINGN_00494 4.72e-145 - - - K ko:K01420 - ko00000,ko03000 Psort location Cytoplasmic, score
HEPIINGN_00495 6.5e-187 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 pyridine
HEPIINGN_00496 6.76e-246 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 Asparaginase
HEPIINGN_00497 1.69e-62 azlD - - E - - - branched-chain amino acid permeases (Azaleucine resistance)
HEPIINGN_00498 1.65e-140 azlC - - E - - - azaleucine resistance protein AzlC
HEPIINGN_00499 0.0 - - - T - - - Putative diguanylate phosphodiesterase
HEPIINGN_00500 6.83e-211 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00501 6.15e-40 - - - S - - - Psort location
HEPIINGN_00502 7.79e-189 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEPIINGN_00503 6.45e-284 alaXL 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Threonine alanine tRNA ligase second additional domain protein
HEPIINGN_00504 0.0 - 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00505 3.21e-193 ytrP 2.7.7.65 - T ko:K13069 - ko00000,ko01000 diguanylate cyclase activity
HEPIINGN_00506 6.26e-96 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00507 6.87e-229 - - - JM - - - Nucleotidyl transferase
HEPIINGN_00508 1.2e-113 - - - J - - - Psort location Cytoplasmic, score
HEPIINGN_00509 2.87e-83 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_00510 2.57e-148 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HEPIINGN_00511 6.61e-181 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEPIINGN_00512 2.13e-176 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 phosphate ABC transporter
HEPIINGN_00513 2.01e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEPIINGN_00514 3.62e-167 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate binding protein
HEPIINGN_00519 1.06e-258 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HEPIINGN_00520 1.23e-177 - - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEPIINGN_00521 3.41e-190 - 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00522 2.16e-83 - - - S - - - Cupin 2, conserved barrel domain protein
HEPIINGN_00523 2.83e-151 - - - G - - - Ribose Galactose Isomerase
HEPIINGN_00524 8.75e-90 - - - S - - - Protein of unknown function (DUF1622)
HEPIINGN_00525 0.0 - - - P ko:K03320 - ko00000,ko02000 Belongs to the P(II) protein family
HEPIINGN_00526 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEPIINGN_00527 7.3e-99 - - - - - - - -
HEPIINGN_00528 3.61e-270 sstT - - E ko:K07862 - ko00000,ko02000 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HEPIINGN_00530 5.68e-287 rny - - D ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEPIINGN_00531 6.1e-135 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00532 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 3 family
HEPIINGN_00533 0.0 - 3.2.1.21 GH3 G ko:K05349 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Glycosyl hydrolase family 3 N-terminal domain protein
HEPIINGN_00534 4.68e-298 - - - T - - - GHKL domain
HEPIINGN_00535 7.71e-166 - - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HEPIINGN_00536 2.46e-220 - - - U - - - domain, Protein
HEPIINGN_00537 1.55e-151 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_00538 9.07e-177 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HEPIINGN_00539 7.68e-174 - - - K ko:K02081 - ko00000,ko03000 DeoR C terminal sensor domain
HEPIINGN_00540 8.02e-226 - - - E - - - Zinc-binding dehydrogenase
HEPIINGN_00541 0.0 - - - H ko:K03483 - ko00000,ko03000 PRD domain
HEPIINGN_00542 0.0 mtlA 2.7.1.197 - G ko:K02798,ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system
HEPIINGN_00543 1.88e-52 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HEPIINGN_00544 5.67e-53 - - - - - - - -
HEPIINGN_00545 4.75e-192 - 3.6.4.12 - K ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Putative DNA-binding domain
HEPIINGN_00548 1.12e-33 - - - - - - - -
HEPIINGN_00549 2.52e-218 - - - L - - - DEAD-like helicases superfamily
HEPIINGN_00550 4.65e-114 dpnC 3.1.21.4 - L ko:K01155 - ko00000,ko01000,ko02048 type II site-specific deoxyribonuclease activity
HEPIINGN_00551 3.61e-78 - - - V - - - restriction endonuclease
HEPIINGN_00553 5.24e-33 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_00554 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00555 2.57e-138 - - - K - - - COG NOG21941 non supervised orthologous group
HEPIINGN_00556 9.59e-256 - - - V - - - MATE efflux family protein
HEPIINGN_00557 1.45e-75 - - - S - - - Bacterial mobilisation protein (MobC)
HEPIINGN_00558 0.0 - - - U - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00559 7.09e-225 - - - K - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00560 2.8e-49 - - - - - - - -
HEPIINGN_00561 1.47e-50 - - - - - - - -
HEPIINGN_00562 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HEPIINGN_00563 1.1e-156 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_00564 4.73e-242 - - - T - - - Histidine kinase
HEPIINGN_00565 9.05e-160 - - - T - - - response regulator receiver
HEPIINGN_00566 7.28e-96 - - - S - - - Bacterial mobilisation protein (MobC)
HEPIINGN_00567 0.0 - - - U - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00569 5.72e-110 - - - KL - - - CHC2 zinc finger
HEPIINGN_00570 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4 family
HEPIINGN_00571 4.94e-15 - - - K - - - Helix-turn-helix domain
HEPIINGN_00572 0.0 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_00574 5.59e-157 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HEPIINGN_00575 1.01e-156 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HEPIINGN_00576 2.35e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEPIINGN_00577 1.04e-174 - - - S ko:K07090 - ko00000 membrane transporter protein
HEPIINGN_00578 2.2e-95 - - - K - - - Transcriptional regulator, MarR family
HEPIINGN_00579 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HEPIINGN_00580 1.06e-261 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP-glucose 4-epimerase
HEPIINGN_00581 3.22e-271 - 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Converts alpha-aldose to the beta-anomer
HEPIINGN_00582 0.0 czcA - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HEPIINGN_00583 1.69e-228 yaaT - - S - - - PSP1 C-terminal domain protein
HEPIINGN_00584 8.06e-17 - - - C - - - 4Fe-4S binding domain
HEPIINGN_00585 2.68e-155 yfiC 2.1.1.223 - S ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HEPIINGN_00586 7.99e-191 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEPIINGN_00587 7.79e-80 yfcE1 - - S ko:K07095 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HEPIINGN_00588 1.51e-186 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 biotin acetyl-CoA-carboxylase ligase
HEPIINGN_00589 4.14e-295 - 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEPIINGN_00590 7.48e-73 PaaY - - S ko:K02617 - ko00000 Bacterial transferase hexapeptide repeat protein
HEPIINGN_00591 2.04e-208 - 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III, delta subunit
HEPIINGN_00592 1.34e-146 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00594 0.0 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HEPIINGN_00595 9.04e-31 - - - - - - - -
HEPIINGN_00596 1.03e-20 - - - - - - - -
HEPIINGN_00597 5.51e-47 - - - S - - - Domain of unknown function (DUF4160)
HEPIINGN_00598 0.0 nifJ 1.2.7.1 - C ko:K03737 ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HEPIINGN_00599 2.79e-131 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00600 3.51e-134 - 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Pseudouridine synthase
HEPIINGN_00601 7.74e-162 - - - K ko:K22293 - ko00000,ko03000 Psort location Cytoplasmic, score 8.96
HEPIINGN_00602 4.2e-126 mntP - - P - - - Probably functions as a manganese efflux pump
HEPIINGN_00604 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEPIINGN_00605 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEPIINGN_00606 1.47e-54 - - - S - - - Domain of unknown function (DUF370)
HEPIINGN_00607 3.4e-256 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEPIINGN_00608 7.54e-44 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein
HEPIINGN_00609 8.39e-169 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEPIINGN_00610 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEPIINGN_00611 4.78e-22 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HEPIINGN_00612 9.55e-88 rnpA 3.1.26.5 - J ko:K03536,ko:K08998 - ko00000,ko01000,ko03016 ribonuclease P activity
HEPIINGN_00613 5.98e-64 yidD - - S ko:K08998 - ko00000 Could be involved in insertion of integral membrane proteins into the membrane
HEPIINGN_00614 1.15e-237 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Membrane protein insertase, YidC Oxa1 family
HEPIINGN_00615 2.29e-201 jag - - S ko:K06346 - ko00000 R3H domain protein
HEPIINGN_00616 0.0 - 3.1.3.6, 3.1.4.16 - F ko:K01119 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 5'-nucleotidase, C-terminal domain
HEPIINGN_00617 7.39e-309 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEPIINGN_00618 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEPIINGN_00619 5.87e-165 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HEPIINGN_00620 2.39e-183 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEPIINGN_00621 1.31e-183 soj - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain
HEPIINGN_00622 1.63e-199 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEPIINGN_00623 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEPIINGN_00626 8.13e-57 - - - S - - - Domain of unknown function (DUF4160)
HEPIINGN_00627 7.6e-52 - - - S - - - Protein of unknown function (DUF2442)
HEPIINGN_00628 5.26e-156 - 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 phosphoglycolate phosphatase, bacterial
HEPIINGN_00629 0.0 - - - - - - - -
HEPIINGN_00631 1.83e-157 - - - C ko:K03499 - ko00000,ko02000 TrkA N-terminal domain protein
HEPIINGN_00632 1.07e-94 trkA2 - - C ko:K03499 - ko00000,ko02000 TrkA N-terminal domain protein
HEPIINGN_00633 1.45e-178 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HEPIINGN_00634 1.55e-276 clcA - - P ko:K03281 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00635 4.75e-268 - - - C ko:K07138 - ko00000 Psort location Cytoplasmic, score
HEPIINGN_00636 3.79e-112 - - - - - - - -
HEPIINGN_00637 2.22e-192 licT - - K ko:K03480,ko:K03488 - ko00000,ko03000 Psort location Cytoplasmic, score
HEPIINGN_00638 0.0 glvC 2.7.1.199, 2.7.1.208 - G ko:K02749,ko:K02750,ko:K02790,ko:K02791 ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00639 0.0 - 3.2.1.122, 3.2.1.86 GH4,GT4 G ko:K01222,ko:K01232 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HEPIINGN_00640 1.58e-238 gluQ 6.1.1.17 - J ko:K01885 ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon
HEPIINGN_00641 1.29e-155 - - - I - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00642 4.25e-306 - - - V - - - MATE efflux family protein
HEPIINGN_00643 0.0 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 CBS domain
HEPIINGN_00644 1.07e-68 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HEPIINGN_00648 0.0 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00649 1.63e-132 - - - S - - - Domain of unknown function (DUF4194)
HEPIINGN_00650 0.0 - - - S - - - DNA replication and repair protein RecF
HEPIINGN_00652 6.08e-309 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00653 6.13e-128 - - - G - - - Phosphoglycerate mutase family
HEPIINGN_00655 2.17e-214 - - - K - - - LysR substrate binding domain
HEPIINGN_00656 0.0 cstA - - T - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00657 2.59e-231 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00658 8.21e-216 - - - K - - - LysR substrate binding domain
HEPIINGN_00659 0.0 - 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN_bind
HEPIINGN_00660 1.26e-303 - - - V - - - MviN-like protein
HEPIINGN_00662 5.63e-179 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEPIINGN_00663 1.89e-73 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HEPIINGN_00665 2.29e-194 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEPIINGN_00666 1.63e-174 - - - S ko:K06940 - ko00000 Psort location Cytoplasmic, score 8.96
HEPIINGN_00667 3.72e-208 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
HEPIINGN_00668 1.56e-192 - - - S ko:K05832 - ko00000,ko00002,ko02000 Branched-chain amino acid ABC transporter, permease protein
HEPIINGN_00669 1.13e-177 - - - S ko:K05833 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_00670 1.04e-274 - 2.7.1.45 - H ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Kinase, PfkB family
HEPIINGN_00671 2.3e-226 PflX 1.97.1.4 - C ko:K04070 - ko00000,ko01000 pyruvate formate lyase activating
HEPIINGN_00672 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HEPIINGN_00673 4.77e-289 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEPIINGN_00674 8.08e-190 yycJ - - S - - - Metallo-beta-lactamase domain protein
HEPIINGN_00675 3.21e-219 dnaC - - L ko:K02315 - ko00000,ko03032 DNA replication protein
HEPIINGN_00676 2.09e-213 dnaD - - - ko:K02086 - ko00000 -
HEPIINGN_00677 2.64e-90 - - - - - - - -
HEPIINGN_00679 5.7e-33 - - - S - - - Transglycosylase associated protein
HEPIINGN_00680 7.46e-165 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEPIINGN_00681 1.42e-308 yrvN - - L ko:K07478 - ko00000 ATPase, AAA family
HEPIINGN_00682 2.86e-93 - - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HEPIINGN_00683 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HEPIINGN_00684 1.79e-92 - - - S - - - Belongs to the UPF0342 family
HEPIINGN_00685 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEPIINGN_00686 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEPIINGN_00687 6.98e-179 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEPIINGN_00688 2e-301 - - - M - - - Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEPIINGN_00689 3.29e-104 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEPIINGN_00690 3.29e-194 - - - S - - - S4 domain protein
HEPIINGN_00691 5.82e-134 - - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HEPIINGN_00692 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEPIINGN_00693 2.88e-101 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEPIINGN_00694 1.49e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEPIINGN_00695 5.2e-188 - - - S - - - haloacid dehalogenase-like hydrolase
HEPIINGN_00696 5.32e-75 - - - L ko:K02237 - ko00000,ko00002,ko02044 Helix-hairpin-helix motif
HEPIINGN_00697 0.0 ppk 2.7.4.1 - H ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEPIINGN_00698 2.06e-120 - - - M - - - Peptidase family M23
HEPIINGN_00699 2.01e-119 - - - S ko:K06402 - ko00000,ko01000,ko01002 Peptidase M50
HEPIINGN_00700 0.0 - - - C - - - Radical SAM domain protein
HEPIINGN_00701 2.34e-131 - - - S - - - Radical SAM-linked protein
HEPIINGN_00702 6.76e-73 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEPIINGN_00703 5.85e-128 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEPIINGN_00704 6.04e-219 ylqF - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEPIINGN_00705 3.17e-150 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEPIINGN_00706 6.76e-84 - - - L ko:K07460 - ko00000 Uncharacterised protein family UPF0102
HEPIINGN_00707 0.0 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HEPIINGN_00708 2.4e-160 - - - S ko:K07099 - ko00000 Ser Thr phosphatase family protein
HEPIINGN_00709 1.28e-293 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEPIINGN_00710 3.34e-139 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEPIINGN_00711 1.89e-316 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEPIINGN_00712 0.0 - - - EK - - - Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HEPIINGN_00713 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HEPIINGN_00714 5.25e-106 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEPIINGN_00716 7.03e-150 - - - S - - - Protein of unknown function (DUF421)
HEPIINGN_00717 0.0 - - - EG ko:K06295 - ko00000 spore germination protein
HEPIINGN_00720 1.85e-316 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEPIINGN_00721 2.39e-156 phoB - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator receiver domain protein
HEPIINGN_00722 0.0 - - - P ko:K03324 - ko00000,ko02000 Na Pi-cotransporter II-like protein
HEPIINGN_00723 3.35e-218 hprK - - H ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEPIINGN_00724 5.12e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HEPIINGN_00725 4.38e-186 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HEPIINGN_00726 8.52e-216 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HEPIINGN_00727 0.0 dnaE 2.7.7.7 - L ko:K02337,ko:K14162 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III alpha subunit
HEPIINGN_00728 2.6e-233 pfkA 2.7.1.11 - H ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEPIINGN_00729 3.7e-88 - - - S - - - YjbR
HEPIINGN_00730 7.24e-154 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_00731 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HEPIINGN_00732 5.35e-152 - - - E - - - AzlC protein
HEPIINGN_00733 3.04e-59 - - - S - - - Branched-chain amino acid transport protein (AzlD)
HEPIINGN_00734 1.63e-197 - 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 RmlD substrate binding domain
HEPIINGN_00735 2.94e-302 pbuX - - F ko:K03458 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00736 3.68e-151 ygfJ 2.7.7.76 - S ko:K07141 ko00790,map00790 ko00000,ko00001,ko01000 MobA-like NTP transferase domain
HEPIINGN_00737 1.43e-181 - - - C - - - FAD binding domain in molybdopterin dehydrogenase
HEPIINGN_00738 2.22e-112 hcrC 1.2.5.3 - C ko:K03518 - ko00000,ko01000 [2Fe-2S] binding domain
HEPIINGN_00739 0.0 xdhD - - C - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00740 9.35e-161 yqeC - - H - - - selenium-dependent hydroxylase accessory protein YqeC
HEPIINGN_00741 1.51e-238 selD 2.7.9.3 - H ko:K01008 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000,ko03016 Synthesizes selenophosphate from selenide and ATP
HEPIINGN_00742 1.45e-136 yedF - - O ko:K04085 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 DsrE/DsrF-like family
HEPIINGN_00743 2.03e-208 csd - - E - - - cysteine desulfurase family protein
HEPIINGN_00744 2.5e-51 - - - S - - - Protein of unknown function (DUF3343)
HEPIINGN_00745 3.28e-236 - - - O ko:K07402 - ko00000 XdhC and CoxI family
HEPIINGN_00746 6.07e-185 - - - S ko:K07402 - ko00000 Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HEPIINGN_00748 1.12e-115 - - - S - - - Protein of unknown function (DUF2812)
HEPIINGN_00749 6.75e-67 - - - K - - - Transcriptional regulator PadR-like family
HEPIINGN_00750 4.39e-212 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein
HEPIINGN_00751 1.95e-114 ybeY 3.5.4.5 - S ko:K01489,ko:K07042 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEPIINGN_00752 2.21e-199 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEPIINGN_00754 6.35e-176 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HEPIINGN_00755 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEPIINGN_00756 3.93e-134 - - - M - - - N-acetylmuramoyl-L-alanine amidase
HEPIINGN_00757 6.67e-279 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 Belongs to the 'phage' integrase family
HEPIINGN_00758 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEPIINGN_00761 5.34e-64 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase, YajC subunit
HEPIINGN_00762 9.18e-290 tgt 2.4.2.29 - J ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEPIINGN_00763 1.01e-249 queA 2.4.99.17 - H ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HEPIINGN_00764 1.2e-263 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartate-semialdehyde dehydrogenase family
HEPIINGN_00765 7.01e-213 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEPIINGN_00766 2.6e-181 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEPIINGN_00767 7e-303 capA - - M ko:K07282 - ko00000 Capsule synthesis protein
HEPIINGN_00768 3.83e-99 - 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 ACT domain
HEPIINGN_00769 9.25e-128 ptbA - - G ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system
HEPIINGN_00770 2.21e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEPIINGN_00771 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HEPIINGN_00772 6.8e-110 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEPIINGN_00773 3.18e-202 nadK 2.7.1.23 - H ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEPIINGN_00774 8.86e-176 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HEPIINGN_00775 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEPIINGN_00776 1.39e-101 - - - S ko:K09775 - ko00000 Divergent PAP2 family
HEPIINGN_00777 3.83e-199 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEPIINGN_00778 8.19e-35 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEPIINGN_00779 2.84e-209 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEPIINGN_00780 1.57e-208 gcp1 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEPIINGN_00781 5.55e-100 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEPIINGN_00782 1.29e-74 asp - - S - - - Asp23 family, cell envelope-related function
HEPIINGN_00783 1.76e-118 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HEPIINGN_00784 7.24e-62 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HEPIINGN_00786 5.49e-240 spoIIIAE - - S ko:K06394 - ko00000 Stage III sporulation protein AE (spore_III_AE)
HEPIINGN_00788 1.78e-30 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HEPIINGN_00790 3.13e-116 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HEPIINGN_00791 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEPIINGN_00792 0.0 - - - M - - - Psort location Cytoplasmic, score
HEPIINGN_00793 8.12e-151 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HEPIINGN_00794 1.59e-211 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEPIINGN_00795 0.0 prkC 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEPIINGN_00796 1.45e-181 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 serine threonine protein phosphatase
HEPIINGN_00797 1.17e-247 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEPIINGN_00798 1.02e-297 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEPIINGN_00799 4.4e-216 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEPIINGN_00800 6.9e-129 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEPIINGN_00801 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEPIINGN_00802 1.21e-128 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HEPIINGN_00803 5.98e-55 NPD7_560 - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HEPIINGN_00804 7.15e-199 yicC - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00805 1.66e-73 - - - S - - - Helix-turn-helix of DDE superfamily endonuclease
HEPIINGN_00806 0.0 oadA 4.1.1.3 - C ko:K01571 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Pyruvate carboxylase, C-terminal domain subunit K01960
HEPIINGN_00807 6.28e-33 gcdC - - I - - - Biotin-requiring enzyme
HEPIINGN_00808 6.3e-267 - - - I - - - Carboxyl transferase domain
HEPIINGN_00809 1.7e-205 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HEPIINGN_00810 4.88e-209 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEPIINGN_00811 5.42e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HEPIINGN_00812 0.0 - - - M - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00813 1.04e-64 - - - S - - - sporulation protein, YlmC YmxH family
HEPIINGN_00814 3.08e-147 - - - S ko:K07025 - ko00000 IA, variant 3
HEPIINGN_00815 2.31e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HEPIINGN_00816 5.05e-99 - - - C - - - Flavodoxin
HEPIINGN_00817 9.28e-110 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00818 2.95e-306 yhbU_1 - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HEPIINGN_00819 4.29e-230 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HEPIINGN_00820 2.13e-189 - - - - - - - -
HEPIINGN_00821 6.41e-163 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 thymidylate kinase
HEPIINGN_00822 2.69e-182 thyX 2.1.1.148 - H ko:K03465 ko00240,ko00670,ko01100,map00240,map00670,map01100 ko00000,ko00001,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
HEPIINGN_00823 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HEPIINGN_00824 4.66e-128 - - - K - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_00825 5e-174 - - - K ko:K03710 - ko00000,ko03000 Psort location Cytoplasmic, score
HEPIINGN_00826 3.81e-225 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HEPIINGN_00827 4.43e-100 pyrI - - F ko:K00610 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002 Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HEPIINGN_00828 5.37e-307 - - - T - - - Histidine kinase
HEPIINGN_00829 7.16e-173 - - - K - - - LytTr DNA-binding domain
HEPIINGN_00830 4.24e-292 - - - P ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEPIINGN_00831 3.01e-187 rluB 5.4.99.19, 5.4.99.22 - J ko:K06178,ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEPIINGN_00832 2.54e-87 ytfJ - - S - - - Sporulation protein YtfJ
HEPIINGN_00833 2.05e-148 - - - - - - - -
HEPIINGN_00834 4.64e-124 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEPIINGN_00835 1.19e-135 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEPIINGN_00836 1.06e-157 - - - S - - - peptidase M50
HEPIINGN_00837 1.85e-40 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HEPIINGN_00838 7.62e-36 - - - S - - - Domain of unknown function (DUF4250)
HEPIINGN_00839 1.11e-191 - - - S - - - Putative esterase
HEPIINGN_00840 8.96e-79 csoR - - S ko:K21600 - ko00000,ko03000 Metal-sensitive transcriptional repressor
HEPIINGN_00841 0.0 copA 3.6.3.4, 3.6.3.54 - P ko:K01533,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 ATPase, P-type (transporting), HAD superfamily, subfamily IC
HEPIINGN_00842 3.67e-131 rbr3A - - C - - - Psort location Cytoplasmic, score
HEPIINGN_00843 8.68e-311 pyrP - - F ko:K02824 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00844 3.64e-251 - 2.8.1.7 - H ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 aminotransferase class V
HEPIINGN_00845 2.11e-291 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEPIINGN_00846 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEPIINGN_00847 1.14e-105 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEPIINGN_00848 3.02e-92 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEPIINGN_00849 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEPIINGN_00850 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEPIINGN_00851 2.62e-242 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEPIINGN_00852 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEPIINGN_00853 5.74e-241 dgt 3.1.5.1 - F ko:K01129 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the dGTPase family. Type 2 subfamily
HEPIINGN_00854 4.98e-129 yvyE - - S - - - YigZ family
HEPIINGN_00855 2.38e-223 - - - M - - - Cysteine-rich secretory protein family
HEPIINGN_00856 1.51e-259 etfA 1.3.1.108 - C ko:K03522,ko:K22432 - ko00000,ko01000,ko04147 Electron transfer flavoprotein FAD-binding domain
HEPIINGN_00857 9.44e-190 - 1.3.1.108 - C ko:K03521,ko:K22431 - ko00000,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00858 3.01e-274 bcd 1.3.8.1 - C ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
HEPIINGN_00859 6.21e-208 hbd 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HEPIINGN_00860 7.71e-183 crt 4.2.1.17 - I ko:K01715 ko00650,ko01200,map00650,map01200 ko00000,ko00001,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HEPIINGN_00861 2.01e-287 thlA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEPIINGN_00862 4.65e-123 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEPIINGN_00863 0.0 cat - - C - - - Acetyl-CoA hydrolase/transferase C-terminal domain
HEPIINGN_00864 8.08e-267 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00866 0.0 - - - C - - - Radical SAM domain protein
HEPIINGN_00867 1.07e-107 - - - K - - - dihydroxyacetone kinase regulator
HEPIINGN_00868 2.29e-183 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEPIINGN_00869 2.69e-185 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEPIINGN_00870 8.63e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEPIINGN_00871 1.37e-99 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HEPIINGN_00872 3.25e-313 ynbB - - P - - - Cystathionine beta-lyase family protein involved in aluminum resistance
HEPIINGN_00873 4.21e-128 - - - S - - - Acetyltransferase (GNAT) domain
HEPIINGN_00874 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEPIINGN_00875 1.8e-283 - - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, family 5
HEPIINGN_00877 8.45e-283 - - - C - - - Psort location Cytoplasmic, score
HEPIINGN_00878 5.19e-269 rmuC - - S ko:K09760 - ko00000 RmuC family
HEPIINGN_00879 5.01e-224 - - - E - - - Transglutaminase-like superfamily
HEPIINGN_00880 8.13e-264 - - - I - - - alpha/beta hydrolase fold
HEPIINGN_00881 5.96e-127 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 acetyltransferase (GNAT) family
HEPIINGN_00882 9.87e-127 - - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEPIINGN_00883 9e-100 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00884 4e-188 - - - I - - - alpha/beta hydrolase fold
HEPIINGN_00885 1e-109 - - - S - - - TIGRFAM C_GCAxxG_C_C family
HEPIINGN_00886 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HEPIINGN_00887 6.33e-254 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00888 3.52e-311 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family
HEPIINGN_00889 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 Galactose-1-phosphate uridyl transferase, C-terminal domain
HEPIINGN_00890 6.26e-170 cutC - - P ko:K06201 - ko00000 Participates in the control of copper homeostasis
HEPIINGN_00891 0.0 - - - S ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_00892 3.68e-170 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC-type multidrug transport system ATPase component
HEPIINGN_00893 4.88e-266 cbiK 4.99.1.3 - H ko:K02190 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00894 1.75e-175 - - - HP - - - small periplasmic lipoprotein
HEPIINGN_00895 2.6e-259 - - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEPIINGN_00896 1.99e-219 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEPIINGN_00897 0.0 cbiD 2.1.1.195 - H ko:K02188 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HEPIINGN_00898 5.63e-176 cobM 2.1.1.133, 2.1.1.271 - H ko:K05936 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 precorrin-4 C11-methyltransferase
HEPIINGN_00899 1.22e-226 cbiG 3.7.1.12 - H ko:K02189 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Cobalamin synthesis G C-terminus
HEPIINGN_00900 6.08e-177 cobJ 2.1.1.131, 2.1.1.272 - H ko:K05934,ko:K21479 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-3B
HEPIINGN_00901 1.88e-166 cobK 1.3.1.106, 1.3.1.54, 1.3.1.76, 4.99.1.4 - H ko:K02304,ko:K05895 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 reductase
HEPIINGN_00902 6.5e-269 cbiT 2.1.1.132, 2.1.1.196 - H ko:K00595,ko:K02191 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Precorrin-6Y C5,15-methyltransferase (Decarboxylating), CbiT subunit
HEPIINGN_00903 1.3e-315 cbiA 6.3.5.11, 6.3.5.9 - H ko:K02224 ko00860,ko01100,ko01120,map00860,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HEPIINGN_00904 1.76e-237 cobT 2.4.2.21 - H ko:K00768 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HEPIINGN_00905 2.41e-113 cobU 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 adenosylcobinamide kinase adenosylcobinamide-phosphate guanylyltransferase
HEPIINGN_00906 1.38e-175 cobS 2.7.8.26 - H ko:K02233 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HEPIINGN_00907 4.33e-69 - 2.7.1.156, 2.7.7.62 - H ko:K02231 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Cobinamide kinase / cobinamide phosphate guanyltransferase
HEPIINGN_00908 1.31e-141 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00909 4.94e-218 cobD 6.3.1.10 - H ko:K02227 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HEPIINGN_00910 8.03e-234 cobD_2 4.1.1.81 - E ko:K04720 ko00860,map00860 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00911 0.0 cobQ 6.3.5.10 - H ko:K02232 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HEPIINGN_00912 1.81e-149 cobH 5.4.99.60, 5.4.99.61 - H ko:K06042 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_00913 6.34e-137 pat 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HEPIINGN_00914 6.28e-104 - - - S ko:K02441 - ko00000 Rhomboid family
HEPIINGN_00915 3.12e-115 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00916 1.51e-300 rlmI 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HEPIINGN_00917 0.0 glnA 6.3.1.2 - S ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEPIINGN_00918 0.0 - 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEPIINGN_00919 1.93e-126 - - - K ko:K22010 - ko00000,ko00002,ko02022 ANTAR domain protein
HEPIINGN_00920 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEPIINGN_00921 0.0 - - - T - - - diguanylate cyclase
HEPIINGN_00922 9.99e-196 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00923 8.33e-99 - - - S - - - Protein of unknown function (DUF3801)
HEPIINGN_00924 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_00925 7.27e-42 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00926 3.99e-198 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_00927 0.0 - - - U - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_00928 1.99e-55 - - - - - - - -
HEPIINGN_00929 0.0 - - - M - - - NlpC P60 family protein
HEPIINGN_00930 3.83e-47 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00931 4.11e-146 - - - S - - - Domain of unknown function (DUF4366)
HEPIINGN_00932 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_00933 0.0 - - - L - - - YodL-like
HEPIINGN_00934 2.15e-211 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00935 6.79e-38 - - - S - - - Putative tranposon-transfer assisting protein
HEPIINGN_00937 4.72e-182 - - - S - - - Nucleotidyl transferase AbiEii toxin, Type IV TA system
HEPIINGN_00938 2.73e-133 - - - K - - - Transcriptional regulator, AbiEi antitoxin
HEPIINGN_00939 1.5e-294 - - - U - - - Relaxase mobilization nuclease domain protein
HEPIINGN_00940 1.34e-68 - - - S - - - Bacterial mobilisation protein (MobC)
HEPIINGN_00941 8.25e-79 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_00942 8.78e-238 - 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HEPIINGN_00943 6.52e-93 - - - K - - - Sigma-70, region 4
HEPIINGN_00944 4.04e-52 - - - S - - - Helix-turn-helix domain
HEPIINGN_00946 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_00949 9.24e-186 - - - G - - - polysaccharide deacetylase
HEPIINGN_00950 7.39e-191 hmrR - - K - - - Transcriptional regulator
HEPIINGN_00951 0.0 apeA - - E - - - M18 family aminopeptidase
HEPIINGN_00952 1.43e-101 - - GH23 M ko:K08309 - ko00000,ko01000,ko01011 Transglycosylase SLT domain
HEPIINGN_00953 2.49e-133 coaE 2.7.1.24 - H ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEPIINGN_00954 1.26e-244 sua 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEPIINGN_00955 2.48e-252 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEPIINGN_00956 4.7e-39 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_00957 2.2e-223 - - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 S1 RNA binding domain protein
HEPIINGN_00958 2.29e-125 - - - K - - - Domain of unknown function (DUF4364)
HEPIINGN_00959 6.56e-312 spoIVA - - P ko:K06398 - ko00000 Stage IV sporulation protein A (spore_IV_A)
HEPIINGN_00960 0.0 aspS 6.1.1.12, 6.1.1.23 - J ko:K01876,ko:K09759 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEPIINGN_00961 3.75e-147 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
HEPIINGN_00962 2.6e-298 - - - V - - - MATE efflux family protein
HEPIINGN_00963 4.48e-99 - - - P ko:K07238 - ko00000,ko02000 Metal cation transporter, ZIP family
HEPIINGN_00966 1.23e-117 yvdD 3.2.2.10 - L ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HEPIINGN_00967 2.95e-120 chrA2 - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HEPIINGN_00968 1.92e-120 chrA1 - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HEPIINGN_00969 2.15e-181 - 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HEPIINGN_00970 1.83e-297 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEPIINGN_00971 1.22e-187 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_00972 3.93e-181 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type spermidine putrescine transport system, permease component I
HEPIINGN_00973 8.61e-251 potA 3.6.3.31 - P ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEPIINGN_00974 4.83e-208 - - - S - - - Domain of unknown function (DUF4340)
HEPIINGN_00975 0.0 - - - N ko:K01992 - ko00000,ko00002,ko02000 transport system
HEPIINGN_00976 7.02e-189 - - - S ko:K01992 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_00977 3.62e-173 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC-type multidrug transport system ATPase component
HEPIINGN_00978 2.24e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HEPIINGN_00980 8.25e-47 - - - K - - - DNA-binding helix-turn-helix protein
HEPIINGN_00981 1.89e-07 - - - - - - - -
HEPIINGN_00985 2.1e-61 - - - S - - - competence protein COMEC
HEPIINGN_00987 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEPIINGN_00988 2.24e-107 - - - C - - - hydrogenase beta subunit
HEPIINGN_00989 1.91e-88 - - - M - - - TupA-like ATPgrasp
HEPIINGN_00990 6.65e-96 cps2J - - S - - - Polysaccharide biosynthesis protein
HEPIINGN_00991 1.16e-65 - - - C - - - Polysaccharide pyruvyl transferase
HEPIINGN_00992 6.89e-133 - - - HJ - - - Sugar-transfer associated ATP-grasp
HEPIINGN_00993 6.62e-29 epsJ2 - - S - - - Glycosyltransferase like family 2
HEPIINGN_00995 4.59e-33 - - - M - - - -O-antigen
HEPIINGN_00997 2.63e-270 - - - C ko:K22227 - ko00000 Iron-sulfur cluster-binding domain
HEPIINGN_00998 1.47e-95 - - - M - - - Glycosyltransferase, group 1 family protein
HEPIINGN_00999 9.39e-278 - 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HEPIINGN_01000 7.53e-211 lspL 5.1.3.6 - GM ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Polysaccharide biosynthesis protein
HEPIINGN_01001 1.02e-195 - - - M - - - Domain of unknown function (DUF1972)
HEPIINGN_01002 3.35e-145 cpsE - - M - - - sugar transferase
HEPIINGN_01005 5.26e-156 - - - S - - - SprT-like family
HEPIINGN_01007 3.61e-42 - - - K - - - sequence-specific DNA binding
HEPIINGN_01009 0.0 - - - L - - - DEAD-like helicases superfamily
HEPIINGN_01010 3.91e-95 - - - L ko:K04763 - ko00000,ko03036 Phage integrase SAM-like domain
HEPIINGN_01012 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEPIINGN_01013 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HEPIINGN_01014 3.25e-182 - 1.4.1.21 - S ko:K06989 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 homoserine dehydrogenase
HEPIINGN_01015 8.49e-210 - - - C - - - D-isomer specific 2-hydroxyacid dehydrogenase catalytic
HEPIINGN_01016 2.79e-183 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEPIINGN_01017 2.89e-142 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HEPIINGN_01018 0.0 - 4.1.1.18, 4.1.1.19 - E ko:K01582,ko:K01583,ko:K01585 ko00310,ko00330,ko00960,ko01100,ko01110,map00310,map00330,map00960,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Orn Lys Arg decarboxylase major
HEPIINGN_01019 0.0 scfB - - C ko:K06871 - ko00000 Radical SAM
HEPIINGN_01020 3.59e-21 scfA - - S - - - RSAM-modified six-cysteine peptide
HEPIINGN_01023 0.0 ushA 3.1.3.5, 3.6.1.45 - F ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEPIINGN_01024 0.0 - 4.2.1.53 - S ko:K10254 - ko00000,ko01000 MCRA family
HEPIINGN_01025 2.14e-57 - - - S - - - TSCPD domain
HEPIINGN_01026 2.01e-211 - 3.1.3.97 - S ko:K07053 - ko00000,ko01000 PHP domain protein
HEPIINGN_01027 0.0 acnA 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 aconitate hydratase
HEPIINGN_01028 0.0 - - - V - - - MATE efflux family protein
HEPIINGN_01029 6.12e-184 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEPIINGN_01030 8.74e-141 tcyB - - P ko:K02029 - ko00000,ko00002,ko02000 ABC transporter, permease protein
HEPIINGN_01031 2.4e-161 fliY1 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEPIINGN_01032 4.69e-220 - - - - - - - -
HEPIINGN_01033 0.0 cls1 - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEPIINGN_01034 2.51e-145 - - - S - - - EDD domain protein, DegV family
HEPIINGN_01035 2.22e-126 - - - K - - - Domain of unknown function (DUF1836)
HEPIINGN_01037 2.48e-111 smpB - - O ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEPIINGN_01038 1.03e-138 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEPIINGN_01039 4.97e-70 - - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEPIINGN_01040 4.73e-92 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEPIINGN_01041 1.28e-59 - - - L - - - RelB antitoxin
HEPIINGN_01042 1.59e-61 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
HEPIINGN_01043 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_01044 3.26e-106 - - - G - - - Domain of unknown function (DUF386)
HEPIINGN_01046 3.92e-208 - - - T - - - GHKL domain
HEPIINGN_01047 5.92e-167 - - - T - - - response regulator
HEPIINGN_01048 0.0 speA 4.1.1.19 - E ko:K01585 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Orn Lys Arg decarboxylase major
HEPIINGN_01049 6.77e-214 speE 2.5.1.16 - H ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HEPIINGN_01050 1.87e-214 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HEPIINGN_01051 2.27e-307 LYS1 1.5.1.7 - E ko:K00290 ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Saccharopine dehydrogenase
HEPIINGN_01052 4.17e-304 nspC 4.1.1.96 - E ko:K13747 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko01000 carboxynorspermidine decarboxylase
HEPIINGN_01054 2.67e-131 - - - S ko:K16789 - ko00000,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_01055 1.24e-47 spoIIID - - K ko:K06283 - ko00000,ko03000 sporulation transcriptional regulator SpoIIID
HEPIINGN_01056 1.13e-172 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEPIINGN_01057 6.54e-157 sigE - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HEPIINGN_01058 1.48e-105 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01060 0.0 nadE 6.3.5.1 - H ko:K01950 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HEPIINGN_01061 2.32e-75 - - - S - - - NusG domain II
HEPIINGN_01062 0.0 - - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEPIINGN_01063 1.48e-217 rluD_2 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEPIINGN_01064 2.29e-302 - - - D - - - G5
HEPIINGN_01065 4.3e-169 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 purine-nucleoside phosphorylase
HEPIINGN_01066 2.63e-99 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HEPIINGN_01067 3.04e-260 tmpC - - S ko:K07335 - ko00000 basic membrane
HEPIINGN_01068 0.0 - 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 transport systems ATPase components
HEPIINGN_01069 1.06e-258 - - - P ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEPIINGN_01070 7.42e-203 - - - P ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEPIINGN_01071 1.3e-148 - - - M - - - Chain length determinant protein
HEPIINGN_01072 2.97e-168 - - - D - - - Capsular exopolysaccharide family
HEPIINGN_01073 2.94e-186 - 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 capsular polysaccharide biosynthesis protein
HEPIINGN_01074 1.48e-138 - - - - - - - -
HEPIINGN_01075 8.29e-200 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEPIINGN_01076 5.92e-238 oppC - - P ko:K02034,ko:K15582 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HEPIINGN_01077 1.53e-241 oppD - - P ko:K15583 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEPIINGN_01078 2.35e-244 appF - - P ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HEPIINGN_01079 0.0 oppA - - E ko:K02035,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC-type oligopeptide transport system periplasmic component
HEPIINGN_01081 0.0 - - - P - - - von Willebrand factor (vWF) type A domain
HEPIINGN_01082 1.53e-216 - - - S - - - ATPase family associated with various cellular activities (AAA)
HEPIINGN_01083 0.0 - - - C - - - domain protein
HEPIINGN_01084 2.03e-222 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_01085 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC-type multidrug transport system ATPase and permease
HEPIINGN_01086 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC-type multidrug transport system ATPase and permease
HEPIINGN_01087 1.19e-73 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HEPIINGN_01088 5.33e-221 - - - P ko:K03324 - ko00000,ko02000 Na Pi-cotransporter
HEPIINGN_01089 4.85e-151 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HEPIINGN_01091 0.0 - - - P ko:K03324 - ko00000,ko02000 Na Pi-cotransporter II-like protein
HEPIINGN_01093 0.0 - 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEPIINGN_01094 7.82e-87 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HEPIINGN_01095 2.41e-298 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HEPIINGN_01096 3.74e-210 thrB 2.7.1.39 - H ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEPIINGN_01097 1.24e-278 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEPIINGN_01098 7.39e-187 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 serine-type D-Ala-D-Ala carboxypeptidase
HEPIINGN_01099 2.11e-268 - - - S - - - Peptidase M16 inactive domain protein
HEPIINGN_01100 0.0 ymfH - - S - - - Peptidase M16 inactive domain
HEPIINGN_01101 6.84e-250 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEPIINGN_01102 2.78e-65 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HEPIINGN_01103 8.65e-53 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HEPIINGN_01104 1.27e-315 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEPIINGN_01105 2.65e-89 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEPIINGN_01107 0.0 rsmF - - J - - - NOL1 NOP2 sun family
HEPIINGN_01108 1.01e-170 yebC - - K - - - Transcriptional regulatory protein
HEPIINGN_01109 6.15e-57 - - - S - - - YoeB-like toxin of bacterial type II toxin-antitoxin system
HEPIINGN_01110 3.28e-52 - - - D - - - Antitoxin component of a toxin-antitoxin (TA) module
HEPIINGN_01111 0.0 dsdA 4.3.1.18 - H ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HEPIINGN_01113 1.64e-293 uxuA 4.2.1.8 - H ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HEPIINGN_01114 0.0 - 1.1.1.57 - G ko:K00040 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase
HEPIINGN_01115 4.5e-124 - - - - - - - -
HEPIINGN_01116 0.0 - - - T - - - Histidine kinase
HEPIINGN_01117 5.82e-183 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_01118 2.88e-170 - - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HEPIINGN_01119 3.65e-235 - - - G - - - Bacterial extracellular solute-binding protein, family 7
HEPIINGN_01120 1.57e-118 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HEPIINGN_01121 2.33e-300 - - - G - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01122 0.0 - 2.7.11.1 - KLT ko:K12132 - ko00000,ko01000,ko01001 PASTA domain protein
HEPIINGN_01123 0.0 gltD 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HEPIINGN_01124 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HEPIINGN_01125 0.0 hcp 1.7.99.1 - C ko:K05601 ko00910,map00910 ko00000,ko00001,ko01000 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HEPIINGN_01126 0.0 gdhA 1.4.1.3, 1.4.1.4 - C ko:K00261,ko:K00262 ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the Glu Leu Phe Val dehydrogenases family
HEPIINGN_01127 5.73e-202 mrp - - D - - - Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HEPIINGN_01128 1.12e-248 spoVB - - S ko:K06409 - ko00000,ko02000 Stage V sporulation protein B
HEPIINGN_01129 0.0 capD - - GM - - - Polysaccharide biosynthesis protein
HEPIINGN_01130 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEPIINGN_01132 1.82e-155 qmcA - - O - - - SPFH Band 7 PHB domain protein
HEPIINGN_01133 1.91e-98 - - - OU - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01134 0.0 apu 2.4.1.25, 3.2.1.133, 3.2.1.135, 3.2.1.20, 3.2.1.54 GH13,GH31,GH77 G ko:K00705,ko:K01187,ko:K01208 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEPIINGN_01135 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HEPIINGN_01136 1.52e-68 - - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HEPIINGN_01137 0.0 ydcP - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HEPIINGN_01138 6.48e-99 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HEPIINGN_01139 1.28e-132 maf - - D ko:K06287 - ko00000 Maf-like protein
HEPIINGN_01140 1.63e-235 - - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein, MreB Mrl family
HEPIINGN_01141 4.03e-162 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HEPIINGN_01142 6.63e-122 - - - S ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HEPIINGN_01143 0.0 mrdA 3.4.16.4 - M ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding protein, transpeptidase domain protein
HEPIINGN_01144 4.06e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HEPIINGN_01145 2.2e-117 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 sulfurtransferase activity
HEPIINGN_01146 1.7e-115 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEPIINGN_01147 0.0 rnj - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEPIINGN_01148 0.0 yybT - - T - - - domain protein
HEPIINGN_01149 1.8e-273 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HEPIINGN_01150 1.51e-94 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HEPIINGN_01151 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEPIINGN_01152 0.0 tilS 6.3.4.19 - D ko:K04075 - ko00000,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEPIINGN_01153 5e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEPIINGN_01154 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEPIINGN_01155 9.61e-159 - - - - - - - -
HEPIINGN_01157 4.15e-233 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Psort location Cytoplasmic, score
HEPIINGN_01158 4.88e-200 - - - S - - - haloacid dehalogenase-like hydrolase
HEPIINGN_01159 1.21e-104 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEPIINGN_01160 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase
HEPIINGN_01161 3.93e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEPIINGN_01162 3.95e-309 pdp 2.4.2.2, 2.4.2.4 - F ko:K00756,ko:K00758 ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HEPIINGN_01163 0.0 trkA - - P ko:K03499 - ko00000,ko02000 K transport systems, NAD-binding component
HEPIINGN_01164 0.0 trkH - - P ko:K03498 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01165 7.86e-281 - - - S - - - SPFH domain-Band 7 family
HEPIINGN_01166 1.32e-248 - - - K - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_01167 4.1e-172 - - - S ko:K06872 - ko00000 Pfam:TPM
HEPIINGN_01168 0.0 clpC - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Belongs to the ClpA ClpB family
HEPIINGN_01169 3.58e-237 - - - I - - - Lipid kinase, YegS Rv2252 BmrU family
HEPIINGN_01170 1.71e-11 - - - I - - - Acyltransferase
HEPIINGN_01171 1.62e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEPIINGN_01172 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEPIINGN_01173 3.56e-36 - - - S - - - Protein of unknown function (DUF4065)
HEPIINGN_01174 3.04e-52 - - - - - - - -
HEPIINGN_01176 1.68e-42 - - - K - - - helix-turn-helix
HEPIINGN_01177 0.0 - - - L - - - restriction endonuclease
HEPIINGN_01178 0.0 - - - L - - - DEAD-like helicases superfamily
HEPIINGN_01179 1.69e-267 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01180 0.0 - - - L - - - Virulence-associated protein E
HEPIINGN_01181 1.49e-63 - - - S - - - Excisionase from transposon Tn916
HEPIINGN_01182 9.43e-280 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_01183 0.0 - 3.4.16.4 - M ko:K05515 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding protein, transpeptidase domain protein
HEPIINGN_01184 3.16e-46 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase SecG subunit
HEPIINGN_01185 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEPIINGN_01186 4.23e-123 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_01187 0.0 lacZ 3.2.1.23, 3.2.1.31 - G ko:K01190,ko:K01195 ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
HEPIINGN_01188 8.03e-311 lacS - - G ko:K03292,ko:K11104,ko:K16209 - ko00000,ko02000 MFS/sugar transport protein
HEPIINGN_01189 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Melibiase
HEPIINGN_01190 0.0 rumA 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEPIINGN_01191 1.48e-213 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_01192 2.55e-305 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GHMP kinase family
HEPIINGN_01195 0.0 - 2.4.1.25 GH77 G ko:K00705 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01196 5.47e-197 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01197 2.31e-195 - - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEPIINGN_01198 4.12e-310 amyE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEPIINGN_01199 8.7e-233 - - - K ko:K02529 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HEPIINGN_01200 3.09e-139 - - - F - - - Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEPIINGN_01201 8.86e-56 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEPIINGN_01202 8.93e-100 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
HEPIINGN_01203 4.49e-60 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HEPIINGN_01204 5.38e-272 napA - - P - - - Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01205 2.97e-211 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEPIINGN_01206 1.3e-240 - - - S - - - Prokaryotic RING finger family 1
HEPIINGN_01207 3.32e-263 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEPIINGN_01208 2.46e-289 spoIVB 3.4.21.116 - S ko:K06399 - ko00000,ko01000,ko01002 stage IV sporulation protein B
HEPIINGN_01209 1.68e-177 spo0A - - K ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HEPIINGN_01211 1.96e-10 - - - S - - - Ribbon-helix-helix protein, copG family
HEPIINGN_01212 1.3e-78 - - - M - - - Host cell surface-exposed lipoprotein
HEPIINGN_01213 1.38e-165 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_01214 1.33e-166 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HEPIINGN_01215 1.04e-117 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEPIINGN_01216 4e-173 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEPIINGN_01217 1.44e-195 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01218 1.27e-272 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HEPIINGN_01219 2.47e-252 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 Metalloprotease
HEPIINGN_01220 1.49e-251 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HEPIINGN_01221 0.0 polC 2.7.7.7 - L ko:K02342,ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEPIINGN_01222 0.0 - - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HEPIINGN_01223 4.34e-75 - - - S - - - Asp23 family, cell envelope-related function
HEPIINGN_01224 1.92e-106 - - - S - - - CBS domain
HEPIINGN_01225 0.0 gltA 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HEPIINGN_01226 3.46e-205 nfnA 1.18.1.2, 1.19.1.1 - C ko:K00528,ko:K16951 ko00920,ko01120,map00920,map01120 ko00000,ko00001,ko01000 domain protein
HEPIINGN_01232 2.86e-197 - - - S ko:K07088 - ko00000 Membrane transport protein
HEPIINGN_01233 9.05e-232 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01234 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEPIINGN_01235 9.51e-240 - - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein, MreB Mrl family
HEPIINGN_01236 1.8e-59 - - - C - - - decarboxylase gamma
HEPIINGN_01237 2.13e-276 gcdB 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 decarboxylase beta subunit
HEPIINGN_01238 7.74e-163 - - - S ko:K06889 - ko00000 Alpha/beta hydrolase family
HEPIINGN_01239 0.0 cstA - - T ko:K06200 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_01240 7.41e-65 - - - S - - - protein, YerC YecD
HEPIINGN_01241 2.71e-72 - - - - - - - -
HEPIINGN_01242 1.02e-129 nt5e 3.1.3.18 - S ko:K01091 ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01243 0.0 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HEPIINGN_01245 3.97e-173 - 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01246 0.0 - - - S ko:K06158 - ko00000,ko03012 ABC transporter
HEPIINGN_01247 2.37e-117 - 2.5.1.30 - S ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Psort location CytoplasmicMembrane, score
HEPIINGN_01248 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HEPIINGN_01249 1.72e-142 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HEPIINGN_01250 5.9e-181 - - - Q - - - Methyltransferase domain protein
HEPIINGN_01251 5.81e-197 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEPIINGN_01252 2.6e-258 yqfD - - M ko:K06438 - ko00000 Putative stage IV sporulation protein YqfD
HEPIINGN_01254 1.66e-235 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HEPIINGN_01255 6.28e-249 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEPIINGN_01256 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 phenylalanyl-tRNA synthetase (beta subunit)
HEPIINGN_01257 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01258 9e-63 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01261 2.73e-293 - - - U - - - Relaxase mobilization nuclease domain protein
HEPIINGN_01262 1.91e-17 - - - K - - - DNA-binding helix-turn-helix protein
HEPIINGN_01263 1.66e-11 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01264 3.39e-281 - - - M - - - FMN-binding domain protein
HEPIINGN_01265 4.05e-119 ftnA 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Iron-storage protein
HEPIINGN_01266 1.26e-05 ftnA 1.16.3.2 - P ko:K02217 - ko00000,ko01000 Iron-storage protein
HEPIINGN_01267 1.01e-202 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEPIINGN_01268 4.34e-73 - - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEPIINGN_01269 9.45e-280 - - - C - - - Psort location Cytoplasmic, score
HEPIINGN_01270 1.58e-204 - - - C - - - Putative TM nitroreductase
HEPIINGN_01271 1.15e-259 nrdB 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEPIINGN_01272 0.0 nrdA 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HEPIINGN_01273 4e-302 fprA2 - - C - - - Psort location Cytoplasmic, score
HEPIINGN_01274 0.0 bcd2 1.3.8.1 - C ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 Acyl-CoA dehydrogenase, C-terminal domain
HEPIINGN_01275 1.55e-99 - - - K - - - Transcriptional regulator
HEPIINGN_01276 4.36e-90 - 1.15.1.2 - C ko:K05919 - ko00000,ko01000 Desulfoferrodoxin, N-terminal domain
HEPIINGN_01277 2.76e-217 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEPIINGN_01278 5.75e-89 - - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEPIINGN_01279 4.53e-160 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HEPIINGN_01280 1.07e-103 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Antioxidant, AhpC TSA family
HEPIINGN_01281 6.01e-61 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_01282 5.48e-11 - - - - - - - -
HEPIINGN_01283 2.22e-36 - - - - - - - -
HEPIINGN_01284 1.59e-27 - - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HEPIINGN_01285 0.0 - - - E ko:K02035,ko:K15584 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEPIINGN_01286 1.23e-176 - - - E ko:K02031,ko:K02032 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEPIINGN_01287 1.08e-176 - - - EP - - - abc transporter atp-binding protein
HEPIINGN_01288 2.91e-189 nikC - - P ko:K02034,ko:K15586 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEPIINGN_01289 1.12e-217 - - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEPIINGN_01290 0.0 - - - V ko:K06147 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01291 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC-type multidrug transport system ATPase and permease
HEPIINGN_01292 8.94e-221 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_01293 4.46e-94 - - - S - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_01294 4.94e-06 - - - K - - - DNA-binding helix-turn-helix protein
HEPIINGN_01295 6.1e-171 - - - K - - - Peptidase S24-like
HEPIINGN_01297 4.82e-164 - - - E - - - IrrE N-terminal-like domain
HEPIINGN_01298 1.9e-104 - - - K - - - DNA-templated transcription, initiation
HEPIINGN_01300 9.56e-130 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_01301 6.68e-197 - - - K - - - DNA binding
HEPIINGN_01302 5.04e-47 - - - S - - - DNA binding domain, excisionase family
HEPIINGN_01303 1.05e-275 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_01308 1.24e-164 - - - K - - - Helix-turn-helix
HEPIINGN_01309 3.26e-65 - - - S - - - regulation of response to stimulus
HEPIINGN_01310 2.51e-165 cobC 3.1.3.73 - G ko:K02226 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01312 4.1e-250 - - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HEPIINGN_01313 4.09e-272 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HEPIINGN_01314 3.07e-119 ptbA - - G ko:K02755,ko:K02756,ko:K02757,ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEPIINGN_01315 1.05e-276 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HEPIINGN_01316 0.0 nagE 2.7.1.193 - G ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01317 2.74e-126 mutX 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 Psort location Cytoplasmic, score 8.96
HEPIINGN_01318 4.63e-64 - - - G - - - Ricin-type beta-trefoil
HEPIINGN_01319 3.71e-117 nfrA2 - - C - - - Nitroreductase family
HEPIINGN_01320 3.23e-118 - - - K - - - Acetyltransferase (GNAT) domain
HEPIINGN_01321 1.66e-61 - - - S - - - Trp repressor protein
HEPIINGN_01322 4.77e-118 yajL 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1 family
HEPIINGN_01323 1.04e-217 - - - Q - - - FAH family
HEPIINGN_01324 5.23e-230 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01325 0.0 - 3.1.3.5, 3.6.1.45 - F ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEPIINGN_01326 1.63e-153 - - - S - - - IA, variant 3
HEPIINGN_01327 1.37e-273 ilvE 2.6.1.42, 4.1.3.38 - E ko:K00826,ko:K02619 ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HEPIINGN_01328 5.5e-194 - - - S - - - Putative esterase
HEPIINGN_01329 1.21e-204 - - - S - - - Putative esterase
HEPIINGN_01330 7.1e-313 - - - F - - - Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEPIINGN_01331 2.55e-304 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01332 4.51e-148 - 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Orotate phosphoribosyltransferase
HEPIINGN_01334 4.93e-207 - - - S - - - Uncharacterised protein family (UPF0160)
HEPIINGN_01335 2.45e-63 - - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HEPIINGN_01337 5.36e-13 - - - MN - - - S-layer homology domain
HEPIINGN_01338 3.93e-218 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEPIINGN_01339 7.67e-294 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HEPIINGN_01340 9.07e-198 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HEPIINGN_01341 7.69e-294 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HEPIINGN_01342 3.92e-218 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HEPIINGN_01343 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HEPIINGN_01344 3.44e-302 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEPIINGN_01345 1.76e-236 - - - S ko:K07035 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_01346 2.53e-283 - - - M - - - hydrolase, family 25
HEPIINGN_01347 2.26e-135 - - - S - - - Domain of unknown function (DUF4830)
HEPIINGN_01348 1.21e-53 - - - G ko:K11189 - ko00000,ko02000 phosphocarrier, HPr family
HEPIINGN_01349 0.0 ptsP 2.7.3.9, 2.7.9.2 - G ko:K01007,ko:K08483 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEPIINGN_01350 1.7e-113 - - - K ko:K03088 - ko00000,ko03021 Sigma-70 region 2
HEPIINGN_01351 1.55e-83 - - - S - - - Putative zinc-finger
HEPIINGN_01355 4.14e-313 - - - M - - - Peptidase, M23 family
HEPIINGN_01356 5.12e-30 - - - - - - - -
HEPIINGN_01357 1.35e-210 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Psort location Cytoplasmic, score
HEPIINGN_01358 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA synthetase
HEPIINGN_01359 9.12e-119 - - - - - - - -
HEPIINGN_01360 7.51e-245 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HEPIINGN_01361 1.87e-174 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HEPIINGN_01362 4.57e-45 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HEPIINGN_01364 3.41e-73 spoVAE - - S ko:K06407 - ko00000 Stage V sporulation protein AE
HEPIINGN_01365 8.64e-230 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HEPIINGN_01366 5.75e-98 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HEPIINGN_01367 5.39e-184 - 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 Serine-type D-Ala-D-Ala carboxypeptidase
HEPIINGN_01368 1.72e-84 - - - S - - - Domain of unknown function (DUF4358)
HEPIINGN_01369 0.0 - - - M ko:K19294 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_01370 5.72e-284 - - - S - - - SGNH hydrolase-like domain, acetyltransferase AlgX
HEPIINGN_01373 9.11e-79 - - - S - - - ParE toxin of type II toxin-antitoxin system, parDE
HEPIINGN_01374 4.54e-54 - - - D - - - Antitoxin Phd_YefM, type II toxin-antitoxin system
HEPIINGN_01375 1.66e-267 dnaJ - - O ko:K03686,ko:K05516 - ko00000,ko03029,ko03036,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEPIINGN_01376 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEPIINGN_01377 1.3e-119 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEPIINGN_01378 2.27e-246 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEPIINGN_01380 7.99e-120 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein T
HEPIINGN_01381 5.62e-293 - - - S ko:K07007 - ko00000 Flavoprotein family
HEPIINGN_01382 8.94e-143 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01383 0.0 - - - K ko:K00375 - ko00000,ko03000 Transcriptional regulator, GntR family
HEPIINGN_01384 4.8e-116 - - - - - - - -
HEPIINGN_01386 0.0 - - - E ko:K03310 - ko00000 amino acid carrier protein
HEPIINGN_01387 5.71e-315 - - - V - - - MATE efflux family protein
HEPIINGN_01388 6.26e-290 - - - I - - - Psort location Cytoplasmic, score 7.50
HEPIINGN_01389 5.77e-209 rlmA 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase
HEPIINGN_01390 0.0 rhlE 3.6.4.13 - L ko:K11927 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Belongs to the DEAD box helicase family
HEPIINGN_01391 0.0 - - - S - - - Protein of unknown function (DUF1015)
HEPIINGN_01392 1.49e-224 - - - S - - - Putative glycosyl hydrolase domain
HEPIINGN_01393 2.59e-102 - - - C ko:K03617 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01394 1.22e-160 - - - C ko:K03613 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_01395 2.09e-242 - - - C ko:K03614 - ko00000 Belongs to the NqrB RnfD family
HEPIINGN_01396 2.06e-151 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HEPIINGN_01397 0.0 - - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HEPIINGN_01398 9.8e-167 - - - T - - - response regulator receiver
HEPIINGN_01399 4.8e-106 - - - - - - - -
HEPIINGN_01400 8.72e-73 - - - - ko:K07726 - ko00000,ko03000 -
HEPIINGN_01401 3.76e-157 - - - E - - - Filamentation induced by cAMP protein fic
HEPIINGN_01402 2.53e-306 - - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Pts system
HEPIINGN_01403 5.36e-307 bglC 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEPIINGN_01404 4.35e-123 - - - K ko:K03488 - ko00000,ko03000 CAT RNA binding domain
HEPIINGN_01405 4.1e-93 - - - - - - - -
HEPIINGN_01407 9.34e-225 - - - S - - - Domain of unknown function (DUF932)
HEPIINGN_01409 1.47e-216 - - - L - - - YqaJ viral recombinase family
HEPIINGN_01410 2.19e-60 - - - S - - - Protein of unknown function (DUF1071)
HEPIINGN_01412 3.69e-13 - - - S - - - Excisionase from transposon Tn916
HEPIINGN_01413 1.51e-189 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_01414 2.19e-270 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEPIINGN_01415 1.01e-152 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEPIINGN_01416 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 Psort location CytoplasmicMembrane, score
HEPIINGN_01417 6.33e-46 - - - C - - - Heavy metal-associated domain protein
HEPIINGN_01418 1.38e-71 ziaR - - K ko:K21903 - ko00000,ko03000 regulatory protein, arsR
HEPIINGN_01419 2.39e-85 - 3.1.2.29 - S ko:K18700 - ko00000,ko01000 thioesterase
HEPIINGN_01421 0.0 - - - C - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01422 2.16e-103 - - - K - - - Winged helix DNA-binding domain
HEPIINGN_01423 1.07e-85 - - - S ko:K08978 - ko00000,ko02000 EamA-like transporter family
HEPIINGN_01424 0.0 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HEPIINGN_01425 6.89e-296 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HEPIINGN_01426 1.89e-252 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HEPIINGN_01427 1.6e-146 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Imidazoleglycerol-phosphate dehydratase
HEPIINGN_01428 2.73e-140 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HEPIINGN_01429 2.39e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HEPIINGN_01430 1.62e-179 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HEPIINGN_01431 9.1e-148 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HEPIINGN_01432 1.58e-202 - 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01433 4.85e-313 - - - V - - - MATE efflux family protein
HEPIINGN_01434 1.09e-249 - - - S ko:K09963 - ko00000 Bacterial protein of unknown function (DUF871)
HEPIINGN_01435 0.0 - 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01436 1.76e-204 murQ 4.2.1.126 - H ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HEPIINGN_01437 3.42e-199 - - - K - - - transcriptional regulator RpiR family
HEPIINGN_01438 4.84e-197 - - - P ko:K07301 - ko00000,ko02000 K -dependent Na Ca exchanger family protein
HEPIINGN_01439 1.58e-81 - - - G - - - Aldolase
HEPIINGN_01440 1.04e-286 - - - P - - - arsenite transmembrane transporter activity
HEPIINGN_01441 5.3e-265 pdxA 1.1.1.262, 1.1.1.408, 1.1.1.409 - C ko:K00097,ko:K22024 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the PdxA family
HEPIINGN_01442 7.92e-218 - 4.3.3.7 - EM ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the DapA family
HEPIINGN_01443 1.76e-277 - - - C - - - alcohol dehydrogenase
HEPIINGN_01444 6.08e-302 - - - G - - - BNR repeat-like domain
HEPIINGN_01445 8.48e-284 - 2.7.1.219, 2.7.1.220 - S ko:K22129 - ko00000,ko01000 Putative sugar-binding N-terminal domain
HEPIINGN_01446 0.0 - - - T ko:K02667 ko02020,map02020 ko00000,ko00001,ko00002,ko02022,ko02035 phosphorelay signal transduction system
HEPIINGN_01447 4.4e-158 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_01448 1.22e-64 - - - L - - - Helix-turn-helix domain
HEPIINGN_01449 0.0 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_01451 1.55e-150 sigF - - K ko:K03091 - ko00000,ko03021 Belongs to the sigma-70 factor family
HEPIINGN_01452 3.93e-99 spoIIAB 2.7.11.1 - T ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HEPIINGN_01453 1.58e-66 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HEPIINGN_01454 7.83e-284 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydrofolate synthase activity
HEPIINGN_01455 5.46e-65 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01456 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEPIINGN_01457 2.1e-250 - - - M - - - Glycosyltransferase like family 2
HEPIINGN_01458 0.0 - - - C - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01459 1.16e-76 epsJ2 - - S - - - Psort location Cytoplasmic, score 9.97
HEPIINGN_01460 0.0 - 1.5.1.20, 2.1.1.10 - H ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 homocysteine S-methyltransferase
HEPIINGN_01461 7.3e-154 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEPIINGN_01462 3.72e-282 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEPIINGN_01463 1.32e-97 - - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator, AsnC family
HEPIINGN_01464 1.07e-115 - - - S - - - Domain of unknown function (DUF4358)
HEPIINGN_01465 3.8e-64 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01466 2.96e-134 - - - V ko:K01990 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_01467 3.26e-63 - - - K - - - helix_turn_helix gluconate operon transcriptional repressor
HEPIINGN_01468 1e-246 - - - M ko:K07011 - ko00000 Glycosyltransferase like family 2
HEPIINGN_01469 1.45e-187 - - - - - - - -
HEPIINGN_01470 2.64e-79 - - - P - - - Belongs to the ArsC family
HEPIINGN_01471 7.31e-38 - - - C ko:K05337 - ko00000 4Fe-4S single cluster domain of Ferredoxin I
HEPIINGN_01472 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEPIINGN_01473 2.33e-237 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEPIINGN_01474 6.38e-178 - 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Nitroreductase family
HEPIINGN_01475 1.1e-201 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEPIINGN_01476 0.0 tetP - - J - - - elongation factor G
HEPIINGN_01477 3.79e-216 - - - O - - - Psort location Cytoplasmic, score
HEPIINGN_01478 0.0 - - - I - - - Psort location Cytoplasmic, score
HEPIINGN_01479 0.0 hgdC2 - - I - - - CoA-substrate-specific enzyme activase
HEPIINGN_01480 1.29e-184 - - - S - - - TraX protein
HEPIINGN_01482 1.34e-145 - - - - - - - -
HEPIINGN_01484 1.82e-226 - - - K - - - AraC-like ligand binding domain
HEPIINGN_01485 4.7e-195 - 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 Aminoglycoside 3-N-acetyltransferase
HEPIINGN_01486 5.88e-164 - - - K ko:K22293 - ko00000,ko03000 Psort location Cytoplasmic, score 8.96
HEPIINGN_01488 8.63e-47 - - - S - - - Putative cell wall binding repeat
HEPIINGN_01490 3.89e-69 - - - - - - - -
HEPIINGN_01491 5.11e-133 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase, peptidase S26
HEPIINGN_01492 0.0 - - - M - - - Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HEPIINGN_01493 2.59e-72 - - - M - - - domain protein
HEPIINGN_01494 4.28e-190 - 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HEPIINGN_01495 1.54e-143 - - - S - - - domain, Protein
HEPIINGN_01496 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HEPIINGN_01497 1.05e-49 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEPIINGN_01498 8.33e-191 - - - S ko:K07052 - ko00000 CAAX amino terminal protease family protein
HEPIINGN_01499 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEPIINGN_01500 1.34e-301 - - - E - - - Peptidase dimerisation domain
HEPIINGN_01501 2.26e-123 glpP - - K ko:K02443 - ko00000,ko03000 Glycerol-3-phosphate responsive antiterminator
HEPIINGN_01502 0.0 glpA 1.1.5.3 - C ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 FAD dependent oxidoreductase
HEPIINGN_01503 2.23e-297 - - - C - - - Psort location Cytoplasmic, score
HEPIINGN_01504 2.72e-82 - - - S - - - protein with conserved CXXC pairs
HEPIINGN_01505 1.42e-245 modC 3.6.3.29 - E ko:K02017 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEPIINGN_01506 5.01e-151 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Molybdate ABC transporter
HEPIINGN_01507 3.33e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, periplasmic molybdate-binding protein
HEPIINGN_01508 5.21e-226 mog - - H - - - Molybdenum cofactor synthesis domain protein
HEPIINGN_01509 3.43e-234 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HEPIINGN_01510 2.45e-109 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HEPIINGN_01511 4.45e-253 moeA2 - - H - - - Psort location Cytoplasmic, score
HEPIINGN_01512 2.47e-101 mobB 2.7.7.77 - H ko:K03753,ko:K13818 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Molybdopterin-guanine dinucleotide biosynthesis protein
HEPIINGN_01513 6.29e-290 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA C-terminal region (domain IV)
HEPIINGN_01514 1.82e-203 - - - - - - - -
HEPIINGN_01515 0.0 - 1.2.7.5 - C ko:K03738,ko:K19515 ko00030,ko00362,ko01100,ko01120,ko01200,map00030,map00362,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Aldehyde ferredoxin oxidoreductase, N-terminal domain
HEPIINGN_01516 4.48e-145 - - - C - - - 4Fe-4S binding domain
HEPIINGN_01518 5.63e-178 fdhD - - C ko:K02379 - ko00000 FdhD/NarQ family
HEPIINGN_01519 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HEPIINGN_01520 0.0 - - - P ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEPIINGN_01521 0.0 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_01522 0.0 fruA 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system
HEPIINGN_01523 4.87e-206 pfkB 2.7.1.56 - H ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HEPIINGN_01524 7.63e-169 fruR - - K ko:K03436 - ko00000,ko03000 COG COG1349 Transcriptional regulators of sugar metabolism
HEPIINGN_01525 0.0 pepD - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEPIINGN_01526 1.3e-212 - - - P ko:K02051 - ko00000,ko00002,ko02000 Menaquinone biosynthesis
HEPIINGN_01527 3.64e-150 - - - K - - - Cyclic nucleotide-monophosphate binding domain
HEPIINGN_01528 1.91e-236 - - - M - - - PFAM Glycosyl transferase family 2
HEPIINGN_01529 1.6e-140 - - - S - - - Flavin reductase-like protein
HEPIINGN_01530 7.7e-111 queT - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01531 2.33e-157 - - - S - - - HAD-hyrolase-like
HEPIINGN_01534 3.57e-260 pfkA 2.7.1.11, 2.7.1.90 - H ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HEPIINGN_01535 4.69e-302 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HEPIINGN_01536 0.0 - - - P ko:K03498 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01539 4.93e-303 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HEPIINGN_01540 1.23e-279 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEPIINGN_01541 3.65e-272 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 aminotransferase class V
HEPIINGN_01542 0.0 fhs 6.3.4.3 - H ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HEPIINGN_01543 1.3e-209 - - - E - - - GDSL-like Lipase/Acylhydrolase
HEPIINGN_01544 2.57e-64 - - - - - - - -
HEPIINGN_01545 3.37e-71 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_01546 1.81e-132 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEPIINGN_01547 3.47e-186 Nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV
HEPIINGN_01548 1.31e-114 yqeG - - S ko:K07015 - ko00000 Mitochondrial PGP phosphatase
HEPIINGN_01549 5.46e-27 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HEPIINGN_01550 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HEPIINGN_01551 1.39e-83 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEPIINGN_01552 3.94e-285 - - - K - - - Cell envelope-related transcriptional attenuator domain
HEPIINGN_01553 1.31e-133 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 HD superfamily hydrolase involved in NAD metabolism
HEPIINGN_01554 1.63e-146 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEPIINGN_01555 1.79e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein, YhbY family
HEPIINGN_01556 1.03e-153 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEPIINGN_01557 4.93e-216 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEPIINGN_01558 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HEPIINGN_01559 8.34e-155 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEPIINGN_01560 2.16e-239 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEPIINGN_01561 0.0 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HEPIINGN_01562 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEPIINGN_01563 6.65e-212 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HEPIINGN_01564 3.39e-181 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEPIINGN_01565 1.07e-75 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEPIINGN_01566 4.37e-39 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HEPIINGN_01567 1.65e-127 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEPIINGN_01568 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HEPIINGN_01569 0.0 addB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HEPIINGN_01570 8.64e-97 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEPIINGN_01571 8.27e-163 - 5.2.1.8 - M ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEPIINGN_01572 4.98e-62 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01573 2.08e-159 - - - - - - - -
HEPIINGN_01574 7.8e-31 - - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HEPIINGN_01575 2.05e-199 ispE 2.7.1.148 - I ko:K00919 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEPIINGN_01576 2.66e-291 aspC - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HEPIINGN_01577 2.04e-105 Lrp - - K - - - Transcriptional regulator, AsnC family
HEPIINGN_01578 4.12e-56 - - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HEPIINGN_01579 0.0 - - - S ko:K09157 - ko00000 UPF0210 protein
HEPIINGN_01580 1.28e-138 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HEPIINGN_01581 1.02e-108 - - - M - - - Putative peptidoglycan binding domain
HEPIINGN_01582 7.2e-227 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HEPIINGN_01583 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 exonuclease SbcC
HEPIINGN_01585 2.29e-48 - - - S - - - Transcriptional Coactivator p15 (PC4)
HEPIINGN_01586 4.41e-133 - - - S - - - metal-dependent phosphohydrolase, HD sub domain
HEPIINGN_01587 1.57e-88 - - - S - - - Domain of unknown function (DUF3842)
HEPIINGN_01588 0.0 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01589 4.26e-108 - - - S - - - small multi-drug export protein
HEPIINGN_01590 3.72e-189 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEPIINGN_01591 0.0 - - - V - - - MATE efflux family protein
HEPIINGN_01592 2.64e-302 - - - S - - - Penicillin-binding protein Tp47 domain a
HEPIINGN_01593 9.98e-212 - - - C - - - FMN-binding domain protein
HEPIINGN_01594 1.09e-93 - - - S - - - FMN_bind
HEPIINGN_01595 9.58e-214 - - - C - - - Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01596 0.0 copA_1 - - P ko:K12950 - ko00000,ko01000 Psort location CytoplasmicMembrane, score
HEPIINGN_01597 3.25e-54 - - - S - - - H( )-transporting two-sector ATPase subunit H.a (A-type ATP synthase) K02121
HEPIINGN_01598 3.58e-301 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HEPIINGN_01599 7.61e-283 - - - T - - - GHKL domain
HEPIINGN_01600 7.39e-166 - - - KT - - - LytTr DNA-binding domain
HEPIINGN_01601 4.18e-77 - - - KT - - - Response regulator of the LytR AlgR family
HEPIINGN_01602 0.0 - - - V - - - antibiotic catabolic process
HEPIINGN_01603 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_01604 1.42e-117 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_01605 3.58e-302 rhaB 2.7.1.5 - H ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Carbohydrate kinase, FGGY family protein
HEPIINGN_01606 0.0 - - - G - - - Catalyzes the conversion of L-arabinose to L-ribulose
HEPIINGN_01607 1.31e-206 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HEPIINGN_01608 3.91e-57 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HEPIINGN_01609 2.7e-22 - - - G - - - Psort location CytoplasmicMembrane, score 9.99
HEPIINGN_01610 1.1e-88 - - - K - - - AraC-like ligand binding domain
HEPIINGN_01611 1.15e-233 - - - S - - - unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HEPIINGN_01612 8.05e-187 - - - S - - - Cupin domain
HEPIINGN_01613 1.62e-121 - - - S - - - Flavin reductase
HEPIINGN_01614 4.85e-102 - - - K - - - Transcriptional regulator
HEPIINGN_01615 1.04e-49 - - - - - - - -
HEPIINGN_01618 0.0 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_01619 1.22e-64 - - - L - - - Helix-turn-helix domain
HEPIINGN_01620 8.72e-114 - - - L ko:K02315 - ko00000,ko03032 DNA replication protein
HEPIINGN_01623 2.39e-228 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase, class I
HEPIINGN_01624 0.0 - 5.4.2.2, 5.4.2.8 - G ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEPIINGN_01625 0.0 - 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HEPIINGN_01626 1.18e-155 - - - S - - - Protein of unknown function, DUF624
HEPIINGN_01627 5.22e-299 - 2.4.1.281 - F ko:K16212 - ko00000,ko01000 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HEPIINGN_01628 1.5e-301 - 5.1.3.11 - G ko:K16213 - ko00000,ko01000 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)
HEPIINGN_01629 4e-265 - 2.4.1.319, 2.4.1.320 - G ko:K18785 - ko00000,ko01000 beta-1,4-mannooligosaccharide phosphorylase
HEPIINGN_01630 1.23e-189 - - - P ko:K02026 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_01631 1.31e-217 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_01632 0.0 - - - G - - - Bacterial extracellular solute-binding protein
HEPIINGN_01633 5.89e-232 - - - K ko:K02529 - ko00000,ko03000 PFAM periplasmic binding protein LacI transcriptional regulator
HEPIINGN_01634 1.75e-277 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HEPIINGN_01635 3.57e-237 - - - G - - - Belongs to the glycosyl hydrolase 5 (cellulase A) family
HEPIINGN_01636 3.46e-267 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HEPIINGN_01637 4.12e-303 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_01640 1.79e-286 - - - P - - - Citrate transporter
HEPIINGN_01641 1.11e-151 ttdB 4.2.1.2, 4.2.1.32 - C ko:K01678,ko:K03780 ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Fumarase C-terminus
HEPIINGN_01642 2.15e-220 - 4.2.1.32 - C ko:K03779 ko00630,map00630 ko00000,ko00001,ko01000 Fumarate hydratase (Fumerase)
HEPIINGN_01643 2.44e-277 - - - P - - - Sodium:sulfate symporter transmembrane region
HEPIINGN_01644 1.57e-133 - - - S - - - Protein of unknown function (DUF1847)
HEPIINGN_01645 3.84e-146 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_01646 4.05e-128 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_01647 5.13e-51 - - - - - - - -
HEPIINGN_01648 3.53e-52 - - - - - - - -
HEPIINGN_01649 2.24e-33 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_01650 1.04e-07 - - - - - - - -
HEPIINGN_01651 3.55e-142 - - - I - - - alpha/beta hydrolase fold
HEPIINGN_01652 1.53e-69 - - - S - - - alpha beta
HEPIINGN_01653 4.69e-292 - - - Q - - - Alkyl sulfatase dimerisation
HEPIINGN_01654 3.95e-175 - - - S - - - Protein of unknown function (DUF1254)
HEPIINGN_01655 0.0 - - - S ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system permease component
HEPIINGN_01656 3.04e-149 - - - V ko:K02003 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEPIINGN_01658 2.33e-189 - - - L - - - Recombinase zinc beta ribbon domain
HEPIINGN_01659 7.42e-161 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEPIINGN_01660 6.12e-179 - - - S - - - Domain of unknown function (DUF4866)
HEPIINGN_01661 1.1e-313 - - - S - - - Putative threonine/serine exporter
HEPIINGN_01662 0.0 - - - - - - - -
HEPIINGN_01663 1.46e-193 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_01664 0.0 - - - S - - - Heparinase II/III-like protein
HEPIINGN_01665 3.43e-298 - - - T ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HEPIINGN_01666 0.0 - 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEPIINGN_01667 3.18e-299 - - - G ko:K02027 - ko00000,ko00002,ko02000 Carbohydrate ABC transporter substrate-binding protein, CUT1 family (TC 3.A.1.1.-)
HEPIINGN_01668 4.1e-222 - - - P ko:K02025 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_01669 2.32e-201 - - - P ko:K02026 - ko00000,ko00002,ko02000 Carbohydrate ABC transporter membrane protein 2, CUT1 family
HEPIINGN_01670 0.0 - 3.2.1.23, 3.2.1.31 - G ko:K01190,ko:K01195 ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Glycosyl hydrolases family 2
HEPIINGN_01671 1.95e-296 - 3.2.1.180 GH88 S ko:K18581 - ko00000,ko01000 Glycosyl Hydrolase Family 88
HEPIINGN_01672 0.0 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2264)
HEPIINGN_01673 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HEPIINGN_01675 5.58e-84 - - - K - - - Cupin domain
HEPIINGN_01676 7.82e-240 - - - M - - - Bacterial extracellular solute-binding protein, family 7
HEPIINGN_01677 2.83e-110 - - - G - - - Tripartite ATP-independent periplasmic transporters, DctQ component
HEPIINGN_01678 7.94e-290 - - - G - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01679 0.0 - - - G - - - Belongs to the glycosyl hydrolase 28 family
HEPIINGN_01680 3.37e-271 - - - G - - - Major Facilitator Superfamily
HEPIINGN_01681 5.4e-118 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain protein
HEPIINGN_01682 0.0 - 3.2.1.40 - G ko:K05989 - ko00000,ko01000 Alpha-L-rhamnosidase N-terminal domain protein
HEPIINGN_01683 1.25e-203 - - - G - - - Xylose isomerase-like TIM barrel
HEPIINGN_01684 0.0 - - - G - - - Glycosyl hydrolases family 43
HEPIINGN_01685 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Glycosyl hydrolases family 2
HEPIINGN_01686 0.0 - - - G - - - MFS/sugar transport protein
HEPIINGN_01687 3.78e-75 - 3.2.1.21 - G ko:K05350 ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEPIINGN_01688 2.72e-206 - - - K - - - transcriptional regulator (AraC family)
HEPIINGN_01689 1.72e-211 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HEPIINGN_01690 0.0 rhaA 5.3.1.14 - G ko:K01813 ko00051,ko01120,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HEPIINGN_01691 3.59e-304 rhaB 2.7.1.5 - H ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Carbohydrate kinase, FGGY family protein
HEPIINGN_01692 1.34e-198 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_01693 7.13e-87 - - - S - - - Putative redox-active protein (C_GCAxxG_C_C)
HEPIINGN_01694 2.85e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEPIINGN_01695 1.09e-111 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01696 8.49e-157 - - - S - - - Domain of unknown function (DUF5058)
HEPIINGN_01697 3.59e-162 - - - - - - - -
HEPIINGN_01698 5.09e-203 - - - G - - - Xylose isomerase-like TIM barrel
HEPIINGN_01699 9.81e-106 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEPIINGN_01700 1.26e-292 - - - M ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HEPIINGN_01702 2.65e-269 fucO 1.1.1.77 - C ko:K00048 ko00630,ko00640,ko01120,map00630,map00640,map01120 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01703 2.22e-313 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01704 1.03e-200 - - - P ko:K07301 - ko00000,ko02000 K -dependent Na Ca exchanger family protein
HEPIINGN_01705 0.0 - - - C - - - NADH oxidase
HEPIINGN_01706 1.06e-184 aroD - - S ko:K06889 - ko00000 X-Pro dipeptidyl-peptidase (S15 family)
HEPIINGN_01707 0.0 - - - G ko:K03292 - ko00000 MFS/sugar transport protein
HEPIINGN_01708 8.53e-185 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_01710 7.43e-257 - 4.1.1.3 - C ko:K01572 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01711 1.16e-213 - 2.7.1.15, 2.7.1.83 - H ko:K00852,ko:K16328 ko00030,ko00240,map00030,map00240 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_01712 1.37e-220 - 2.7.1.40 - H ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Pyruvate kinase, barrel domain
HEPIINGN_01713 2.22e-131 yfcE - - S ko:K07095 - ko00000 Phosphoesterase
HEPIINGN_01714 1.1e-297 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01715 0.0 agcS_2 - - E ko:K03310 - ko00000 amino acid carrier protein
HEPIINGN_01716 4.2e-268 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 Thermophilic metalloprotease (M29)
HEPIINGN_01717 5.61e-113 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HEPIINGN_01718 1.19e-258 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HEPIINGN_01719 3.45e-64 ylxR - - K ko:K07742 - ko00000 Psort location Cytoplasmic, score 8.96
HEPIINGN_01720 5.95e-84 - - - J - - - ribosomal protein
HEPIINGN_01721 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEPIINGN_01722 1.81e-85 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEPIINGN_01723 6.63e-232 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 domain protein
HEPIINGN_01724 6.96e-207 truB 5.4.99.25 - J ko:K03177 - ko00000,ko01000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEPIINGN_01725 2.9e-225 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEPIINGN_01726 1.59e-287 pgk 2.7.2.3, 5.3.1.1 - G ko:K00927,ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Phosphoglycerate kinase
HEPIINGN_01727 2.46e-172 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEPIINGN_01728 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEPIINGN_01729 1.24e-256 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEPIINGN_01730 1.56e-93 - - - S - - - Domain of unknown function (DUF3783)
HEPIINGN_01731 6.49e-245 aroF 2.5.1.54 - E ko:K03856 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 synthase
HEPIINGN_01732 3.25e-107 ybaK - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEPIINGN_01734 1.16e-103 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEPIINGN_01735 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEPIINGN_01736 4.15e-258 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HEPIINGN_01737 3.44e-132 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEPIINGN_01738 3.29e-191 - - - F - - - IMP cyclohydrolase-like protein
HEPIINGN_01739 2.1e-292 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 AICARFT IMPCHase bienzyme
HEPIINGN_01740 2.11e-315 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HEPIINGN_01741 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphoribosylformylglycinamidine synthase
HEPIINGN_01742 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEPIINGN_01743 3.4e-163 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEPIINGN_01744 7.73e-256 - - - KT ko:K02647 - ko00000,ko03000 Psort location Cytoplasmic, score
HEPIINGN_01745 2.79e-177 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HEPIINGN_01746 2.14e-205 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HEPIINGN_01747 2.28e-180 - - - D ko:K21471 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HEPIINGN_01749 1.09e-278 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HEPIINGN_01750 4.28e-191 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEPIINGN_01751 9.45e-14 - - - E - - - Parallel beta-helix repeats
HEPIINGN_01752 1.34e-160 - - - - - - - -
HEPIINGN_01753 5.22e-231 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HEPIINGN_01754 0.0 gltA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 citrate synthase
HEPIINGN_01755 1.62e-103 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01756 6.71e-241 gap 1.2.1.12 - C ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEPIINGN_01757 9.43e-144 - - - L - - - Phage integrase, N-terminal SAM-like domain
HEPIINGN_01769 1.26e-42 - - - K - - - sequence-specific DNA binding
HEPIINGN_01771 1.02e-153 - - - S - - - SprT-like family
HEPIINGN_01773 2.23e-50 - - - - - - - -
HEPIINGN_01774 0.0 ppdK 2.7.9.1 - G ko:K01006 ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the PEP-utilizing enzyme family
HEPIINGN_01775 1.04e-139 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEPIINGN_01776 5.8e-137 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEPIINGN_01777 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEPIINGN_01778 3.29e-242 - - - - - - - -
HEPIINGN_01779 0.0 - - - S - - - Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HEPIINGN_01780 0.0 - - - G - - - Belongs to the glycosyl hydrolase 2 family
HEPIINGN_01781 0.0 - - - V ko:K06147 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01782 0.0 - - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEPIINGN_01783 8.99e-114 - - - K - - - MarR family
HEPIINGN_01784 4.77e-216 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HEPIINGN_01785 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEPIINGN_01786 1.02e-234 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HEPIINGN_01787 2.92e-108 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEPIINGN_01788 5.96e-304 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEPIINGN_01789 2.55e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HEPIINGN_01790 2.18e-218 fabD 2.3.1.39 - I ko:K00645 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 malonyl CoA-acyl carrier protein transacylase
HEPIINGN_01791 3.65e-251 - - - S - - - Nitronate monooxygenase
HEPIINGN_01792 1.71e-211 fabK 1.3.1.9 - S ko:K02371 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Psort location Cytoplasmic, score
HEPIINGN_01793 1.85e-213 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEPIINGN_01794 5.43e-228 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HEPIINGN_01795 3.88e-204 accD 2.1.3.15, 6.4.1.2 - I ko:K01962,ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEPIINGN_01796 3.48e-44 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEPIINGN_01797 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEPIINGN_01798 0.0 - - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein FtsQ
HEPIINGN_01799 2.73e-263 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEPIINGN_01800 7.62e-290 - - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01801 3.21e-102 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEPIINGN_01802 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEPIINGN_01803 0.0 spoVD 3.4.16.4 - M ko:K03587,ko:K08384 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding Protein
HEPIINGN_01804 6.55e-102 - - - - - - - -
HEPIINGN_01805 3.99e-231 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEPIINGN_01806 1.44e-47 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HEPIINGN_01807 2.81e-75 - - - C - - - Psort location Cytoplasmic, score
HEPIINGN_01808 7.9e-130 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HEPIINGN_01809 1.3e-149 - - - C - - - NADPH-dependent FMN reductase
HEPIINGN_01810 1.6e-26 - - - DZ - - - guanyl-nucleotide exchange factor activity
HEPIINGN_01811 0.0 lacZ 3.2.1.23, 3.2.1.31 - G ko:K01190,ko:K01195 ko00040,ko00052,ko00511,ko00531,ko00600,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00052,map00511,map00531,map00600,map00860,map00944,map00983,map01100,map01110,map04142 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 2 family
HEPIINGN_01812 8.61e-89 - - - S - - - COG NOG18757 non supervised orthologous group
HEPIINGN_01813 8.22e-213 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_01814 2.1e-163 - - - O ko:K03686 - ko00000,ko03029,ko03110 Psort location Cytoplasmic, score
HEPIINGN_01815 7.58e-62 - - - - - - - -
HEPIINGN_01816 1.34e-131 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_01817 2.57e-149 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01818 6.86e-154 - - - K - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01819 7.83e-159 - - - I - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01820 2.84e-210 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_01821 1.4e-235 eda 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase
HEPIINGN_01822 7.93e-248 - 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Kinase, PfkB family
HEPIINGN_01823 1.6e-215 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HEPIINGN_01824 6.11e-187 - 1.1.1.69 - IQ ko:K00046 - ko00000,ko01000 PFAM Short-chain dehydrogenase reductase SDR
HEPIINGN_01825 1.88e-294 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01826 0.0 clpB - - O ko:K03695,ko:K03696 ko01100,ko04213,map01100,map04213 ko00000,ko00001,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEPIINGN_01827 1.54e-87 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HEPIINGN_01828 4.83e-98 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEPIINGN_01830 7.65e-187 ttcA2 - - H - - - Belongs to the TtcA family
HEPIINGN_01831 2.68e-294 alr 5.1.1.1 - M ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEPIINGN_01832 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEPIINGN_01833 6.15e-234 - - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase
HEPIINGN_01834 6.03e-289 - - - - - - - -
HEPIINGN_01835 0.0 - - - M - - - Diguanylate cyclase, GGDEF domain
HEPIINGN_01836 2.37e-292 - - - V - - - Glycosyl transferase, family 2
HEPIINGN_01837 5.65e-94 - - - M - - - Glycosyltransferase Family 4
HEPIINGN_01838 0.0 - - - S - - - O-Antigen ligase
HEPIINGN_01839 2.76e-247 - - GT2 M ko:K19427 - ko00000,ko01000 Glycosyltransferase group 2 family protein
HEPIINGN_01840 1.42e-70 - - - K - - - Probable zinc-ribbon domain
HEPIINGN_01841 5.16e-291 ackA 2.7.2.1 - H ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEPIINGN_01842 1.95e-271 - - - S - - - Belongs to the UPF0348 family
HEPIINGN_01843 0.0 - 1.4.1.13, 1.4.1.14 - C ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HEPIINGN_01844 0.0 glpK 2.7.1.30 - H ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEPIINGN_01846 3.96e-75 - - - K - - - Transcriptional regulator, HxlR family
HEPIINGN_01847 4.86e-77 - - - G - - - Cupin domain
HEPIINGN_01848 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_01851 1.03e-127 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide
HEPIINGN_01852 1.39e-166 - - - K - - - LytTr DNA-binding domain
HEPIINGN_01853 7.93e-289 - - - T - - - GHKL domain
HEPIINGN_01855 4.63e-283 - - - U - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01856 6.08e-226 - - - K - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01858 1.65e-148 - - - S - - - Macro domain
HEPIINGN_01859 6.98e-38 - - - S - - - Domain of unknown function (DUF4433)
HEPIINGN_01860 5.73e-09 - - - GK - - - ROK family
HEPIINGN_01862 6.19e-136 - - - K - - - Bacterial regulatory proteins, tetR family
HEPIINGN_01863 0.0 - - - S ko:K07003 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_01864 0.0 - - - S ko:K01421 - ko00000 Psort location Cellwall, score
HEPIINGN_01865 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HEPIINGN_01866 2.82e-279 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEPIINGN_01867 2.26e-213 coaX 2.7.1.33 - H ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HEPIINGN_01868 1.3e-239 - - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase NAD-binding domain protein
HEPIINGN_01869 6.16e-131 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01870 6.31e-51 - - - S - - - SPP1 phage holin
HEPIINGN_01871 1.29e-31 - - - - - - - -
HEPIINGN_01872 1.77e-93 - 3.4.17.14 - M ko:K08640 - ko00000,ko01000,ko01002,ko01011 Peptidase M15A
HEPIINGN_01874 6.19e-244 - - - N - - - Bacterial Ig-like domain (group 2)
HEPIINGN_01875 1.67e-33 - - - - - - - -
HEPIINGN_01876 0.0 - - - N - - - domain, Protein
HEPIINGN_01877 2.27e-201 yabE - - S - - - G5 domain
HEPIINGN_01878 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEPIINGN_01879 6.85e-259 glgC 2.7.7.27 - H ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HEPIINGN_01880 1.67e-273 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HEPIINGN_01881 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HEPIINGN_01882 2.35e-47 - - - S - - - Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
HEPIINGN_01883 1.03e-111 - - - - - - - -
HEPIINGN_01884 1.63e-177 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEPIINGN_01885 2.72e-56 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEPIINGN_01886 1.75e-99 - - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEPIINGN_01887 3.52e-118 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEPIINGN_01888 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEPIINGN_01889 7.99e-191 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEPIINGN_01890 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEPIINGN_01891 1.54e-87 - - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEPIINGN_01892 2e-150 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HEPIINGN_01893 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEPIINGN_01894 1.24e-99 - - - M - - - glycosyl transferase group 1
HEPIINGN_01895 1.01e-156 - - - S ko:K09974 - ko00000 Domain of unknown function (DUF1287)
HEPIINGN_01896 9.93e-208 fba 4.1.2.13 - G ko:K01624 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HEPIINGN_01897 1.07e-172 yacO 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEPIINGN_01898 0.0 - - - P - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01899 4.96e-282 - - - E ko:K03310 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01900 1.72e-315 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HEPIINGN_01901 2.41e-148 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEPIINGN_01902 1.74e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEPIINGN_01903 6.18e-115 thiW - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_01904 0.0 - 2.4.1.20 GT36 G ko:K00702 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycosyltransferase family 36
HEPIINGN_01905 1.53e-242 - - - K ko:K02529,ko:K03604 - ko00000,ko03000 sugar-binding domain protein
HEPIINGN_01906 0.0 - - - G - - - ABC-type sugar transport system periplasmic component
HEPIINGN_01907 3.83e-231 - - - P ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEPIINGN_01908 2.67e-192 - - - P ko:K02026 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_01909 2.84e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEPIINGN_01910 7.25e-213 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEPIINGN_01911 9.19e-168 - - - P ko:K02050 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HEPIINGN_01912 3.09e-133 - - - P ko:K02049 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEPIINGN_01913 2.85e-277 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HEPIINGN_01914 2.15e-281 - - - - - - - -
HEPIINGN_01915 8.69e-96 ydiB - - S ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HEPIINGN_01916 1.43e-161 yeaZ - - O ko:K14742 - ko00000,ko03016 Universal bacterial protein YeaZ
HEPIINGN_01917 1.79e-105 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HEPIINGN_01918 2.42e-146 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEPIINGN_01919 2.37e-307 - - - V - - - Polysaccharide biosynthesis C-terminal domain
HEPIINGN_01920 1.6e-171 - - - E - - - Pyridoxal-phosphate dependent protein
HEPIINGN_01921 2.82e-83 - - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEPIINGN_01922 4.48e-312 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEPIINGN_01923 1.59e-49 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HEPIINGN_01924 4.87e-45 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HEPIINGN_01925 1.1e-125 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEPIINGN_01926 0.0 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HEPIINGN_01927 4.88e-54 ptsH - - G ko:K11184,ko:K11189 - ko00000,ko02000 phosphocarrier, HPr family
HEPIINGN_01928 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEPIINGN_01929 8.87e-176 - - - U - - - Protein of unknown function (DUF1700)
HEPIINGN_01930 3.47e-69 - - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HEPIINGN_01931 1.37e-183 - - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Amino acid ABC transporter substrate-binding protein, PAAT family (TC 3.A.1.3.-)
HEPIINGN_01932 3.25e-182 tcyN - - E ko:K10010,ko:K16960 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Amino acid ABC transporter ATP-binding protein, PAAT family
HEPIINGN_01933 9.26e-149 - - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 amino acid ABC transporter
HEPIINGN_01934 1.15e-212 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HEPIINGN_01935 6.41e-193 - - - M - - - Psort location Cytoplasmic, score
HEPIINGN_01936 3.14e-293 - - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Major Facilitator
HEPIINGN_01937 1.04e-308 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 O-acetylhomoserine
HEPIINGN_01939 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEPIINGN_01940 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HEPIINGN_01941 1.12e-307 leuC 4.2.1.33, 4.2.1.35, 4.2.1.85 - E ko:K01703,ko:K20452 ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEPIINGN_01942 7.69e-115 leuD 4.2.1.33, 4.2.1.35, 4.2.1.85 - E ko:K01704,ko:K20453 ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HEPIINGN_01943 9.11e-262 leuB 1.1.1.85 - C ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HEPIINGN_01944 8.23e-170 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC-type polar amino acid transport system ATPase component
HEPIINGN_01945 6.48e-167 ArtM - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 acid ABC transporter
HEPIINGN_01946 4.31e-161 artP - - ET ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEPIINGN_01947 2.26e-129 - - - C - - - Nitroreductase family
HEPIINGN_01949 4.33e-91 - - - S - - - Threonine/Serine exporter, ThrE
HEPIINGN_01950 4.28e-181 - - - S - - - Putative threonine/serine exporter
HEPIINGN_01951 1.3e-191 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 NLPA lipoprotein
HEPIINGN_01952 1.21e-208 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEPIINGN_01953 4.1e-143 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-type metal ion transport system permease component
HEPIINGN_01954 1.96e-315 metY 2.5.1.49 - E ko:K01740 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko01000 O-acetylhomoserine aminocarboxypropyltransferase cysteine synthase
HEPIINGN_01955 2.71e-233 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HEPIINGN_01956 1.73e-214 - - - S - - - EDD domain protein, DegV family
HEPIINGN_01957 8.86e-127 trmL 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEPIINGN_01958 1.06e-161 - 2.7.1.35 - H ko:K00868 ko00750,ko01100,map00750,map01100 ko00000,ko00001,ko01000 Pyridoxal kinase
HEPIINGN_01961 0.0 - - - C - - - 4Fe-4S binding domain protein
HEPIINGN_01962 9.64e-317 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 tRNA methylthiotransferase YqeV
HEPIINGN_01963 3.47e-286 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEPIINGN_01964 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HEPIINGN_01965 8.87e-88 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_01966 6.01e-120 - - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HEPIINGN_01967 8.45e-38 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HEPIINGN_01968 0.0 - - - C - - - FeS-containing Cyanobacterial-specific oxidoreductase
HEPIINGN_01969 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HEPIINGN_01970 2.29e-145 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEPIINGN_01971 4.66e-117 - - - S - - - Psort location
HEPIINGN_01972 9.22e-223 - - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 PBP superfamily domain
HEPIINGN_01974 2.34e-315 - - - V - - - MatE
HEPIINGN_01975 4.45e-117 - - - G - - - Ricin-type beta-trefoil
HEPIINGN_01976 9.33e-197 - - - - - - - -
HEPIINGN_01978 7.07e-250 lldD - - C - - - FMN-dependent dehydrogenase
HEPIINGN_01979 1.36e-215 rluC 5.4.99.24 - J ko:K06179 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEPIINGN_01980 2.36e-138 - - - - - - - -
HEPIINGN_01981 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEPIINGN_01982 1.14e-74 hinT - - FG ko:K02503 - ko00000,ko04147 Psort location Cytoplasmic, score
HEPIINGN_01983 6.61e-123 - 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Psort location Cytoplasmic, score
HEPIINGN_01984 0.0 - - - S ko:K02238 - ko00000,ko00002,ko02044 Psort location CytoplasmicMembrane, score
HEPIINGN_01985 3.16e-234 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Psort location Cytoplasmic, score
HEPIINGN_01986 2.32e-135 rnmV 3.1.26.8 - L ko:K05985 - ko00000,ko01000 Ribonuclease M5
HEPIINGN_01987 1.85e-75 - - - K - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_01988 3.39e-91 - - - I - - - Alpha/beta hydrolase family
HEPIINGN_01989 2.77e-94 mgrA - - K - - - Transcriptional regulators
HEPIINGN_01990 2.07e-171 - - - F - - - Psort location Cytoplasmic, score
HEPIINGN_01991 1.62e-225 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_01992 3.71e-10 - - - L - - - SNF2 family N-terminal domain
HEPIINGN_01993 6.79e-40 - - - L - - - Integrase core domain
HEPIINGN_01994 1e-47 yeiR - - P - - - cobalamin synthesis protein
HEPIINGN_01995 2.07e-149 - - - S - - - Membrane
HEPIINGN_01996 1.99e-122 - - - Q - - - Isochorismatase family
HEPIINGN_01997 3.04e-117 - - - S - - - domain protein
HEPIINGN_01998 4.33e-160 sfsA - - S ko:K06206 - ko00000 Belongs to the SfsA family
HEPIINGN_01999 1.94e-90 - 1.15.1.2 - C ko:K05919 - ko00000,ko01000 Desulfoferrodoxin
HEPIINGN_02000 1.91e-107 - - - S - - - Protein of unknown function (DUF523)
HEPIINGN_02001 6.26e-50 - - - S - - - HAD hydrolase, family IIB
HEPIINGN_02002 1.83e-105 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02003 3.2e-109 - 3.1.1.29 - S ko:K04794 - ko00000,ko01000,ko03012 Peptidyl-tRNA hydrolase PTH2
HEPIINGN_02004 1.05e-49 - - - I - - - Alpha/beta hydrolase family
HEPIINGN_02005 1.34e-233 - - - S - - - Protein of unknown function (DUF5131)
HEPIINGN_02006 0.0 - - - S - - - Protein of unknown function DUF262
HEPIINGN_02007 2.94e-198 punA 2.4.2.1 - F ko:K03783 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HEPIINGN_02008 8.89e-107 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEPIINGN_02009 7.23e-107 cysK 2.5.1.47, 4.2.1.22 - E ko:K01697,ko:K01738 ko00260,ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEPIINGN_02010 4.51e-111 hsp18 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEPIINGN_02011 1.28e-258 - - - C ko:K18369 ko00640,map00640 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HEPIINGN_02012 7.03e-117 msrA 1.8.4.11 - O ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEPIINGN_02013 3.18e-13 - - - S ko:K07150 - ko00000 membrane
HEPIINGN_02014 4.78e-115 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02015 8.17e-124 - 3.6.1.22 - L ko:K03426 ko00760,ko01100,ko04146,map00760,map01100,map04146 ko00000,ko00001,ko01000 Hydrolase, NUDIX family
HEPIINGN_02016 2.58e-45 - - - D - - - Filamentation induced by cAMP protein fic
HEPIINGN_02017 9.9e-144 - - - Q - - - DREV methyltransferase
HEPIINGN_02018 1.78e-145 - - - Q ko:K15256 - ko00000,ko01000,ko03016 Methyltransferase domain protein
HEPIINGN_02019 1.37e-214 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02020 5.11e-157 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
HEPIINGN_02021 1.09e-15 - - - - - - - -
HEPIINGN_02022 5.3e-187 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02023 1.99e-199 - - - H - - - Leucine carboxyl methyltransferase
HEPIINGN_02024 6.25e-217 - 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Ketopantoate reductase PanE/ApbA
HEPIINGN_02025 1.52e-150 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
HEPIINGN_02026 3.92e-143 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
HEPIINGN_02027 1.55e-109 - - - - - - - -
HEPIINGN_02028 6.64e-170 - - - - - - - -
HEPIINGN_02029 9.78e-38 - - - S ko:K09163 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEPIINGN_02031 5.25e-60 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_02032 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_02033 1.72e-212 - - - D - - - Psort location Cytoplasmic, score
HEPIINGN_02034 1.92e-118 - - - L - - - YodL-like
HEPIINGN_02035 5.41e-38 - - - S - - - Putative tranposon-transfer assisting protein
HEPIINGN_02036 0.0 - - - L - - - resolvase
HEPIINGN_02037 4.38e-35 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02038 2.08e-213 - - - D - - - Plasmid recombination enzyme
HEPIINGN_02039 9.31e-93 - - - S - - - Replication initiator protein A (RepA) N-terminus
HEPIINGN_02040 1.06e-88 - - - S - - - Cysteine-rich VLP
HEPIINGN_02041 2.24e-156 - - - S - - - COG NOG15879 non supervised orthologous group
HEPIINGN_02042 3.2e-173 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_02043 5.73e-283 - - - EGP ko:K08217 - br01600,ko00000,ko01504,ko02000 Major facilitator superfamily
HEPIINGN_02044 4.53e-72 - - - - - - - -
HEPIINGN_02045 1.75e-73 - - - S - - - Protein of unknown function (DUF2500)
HEPIINGN_02046 1.57e-176 - - - S - - - AAA domain
HEPIINGN_02047 7.94e-201 - - - M - - - Psort location Cytoplasmic, score
HEPIINGN_02048 8.17e-98 - - - - - - - -
HEPIINGN_02049 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02050 6.59e-65 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02053 3.62e-291 - - - U - - - Relaxase mobilization nuclease domain protein
HEPIINGN_02054 2.7e-17 - - - K - - - DNA-binding helix-turn-helix protein
HEPIINGN_02055 7.84e-13 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02056 3.85e-236 mod 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 PFAM DNA methylase
HEPIINGN_02057 1.65e-302 - 3.1.21.5 - KL ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HEPIINGN_02058 5e-37 - - - - - - - -
HEPIINGN_02059 0.0 - - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HEPIINGN_02060 1.46e-101 - - - - - - - -
HEPIINGN_02061 4.65e-45 - - - - - - - -
HEPIINGN_02062 6.09e-254 - - - S - - - Psort location CytoplasmicMembrane, score 9.99
HEPIINGN_02063 3.33e-243 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEPIINGN_02064 3.54e-154 - - - K - - - response regulator receiver
HEPIINGN_02065 0.0 - - - I ko:K06132 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Phospholipase D. Active site motifs.
HEPIINGN_02066 0.0 - - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEPIINGN_02067 3.4e-77 - - - - - - - -
HEPIINGN_02072 3.86e-142 - - - M - - - Domain of unknown function (DUF4367)
HEPIINGN_02073 3.08e-114 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_02075 1.57e-45 - - - - - - - -
HEPIINGN_02076 2.39e-182 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02077 4.46e-20 nagE 2.7.1.193 - G ko:K02803,ko:K02804 ko00520,ko02060,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02078 2.09e-22 - - - - - - - -
HEPIINGN_02079 9.78e-55 yihX - - S ko:K07025 - ko00000 HAD hydrolase, family IA, variant 3
HEPIINGN_02080 2.35e-147 - - - G - - - Aldose 1-epimerase
HEPIINGN_02081 3.15e-49 pfbA - - M ko:K13925 ko05100,map05100 ko00000,ko00001 Pectate lyase superfamily protein
HEPIINGN_02082 7.51e-72 - - - E ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HEPIINGN_02083 1.15e-80 - - - S - - - Beta-lactamase superfamily III
HEPIINGN_02084 1.55e-145 - - - G - - - Binding-protein-dependent transport system inner membrane component
HEPIINGN_02085 3.81e-111 - - - G - - - Binding-protein-dependent transport system inner membrane component
HEPIINGN_02086 4.13e-182 - - - G - - - Bacterial extracellular solute-binding protein
HEPIINGN_02087 8.01e-189 - - - M - - - Phosphotransferase enzyme family
HEPIINGN_02088 1.87e-195 - - - JM - - - Nucleotidyl transferase
HEPIINGN_02089 3.18e-162 - 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Domain of unknown function
HEPIINGN_02090 2.13e-217 - - - K - - - helix_turn _helix lactose operon repressor
HEPIINGN_02091 9.38e-129 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
HEPIINGN_02092 2.75e-113 - - - - - - - -
HEPIINGN_02094 2.81e-77 - - - K - - - DNA-templated transcription, initiation
HEPIINGN_02096 1.68e-155 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_02097 4.18e-196 - - - K - - - DNA binding
HEPIINGN_02098 1.42e-39 - - - K - - - Helix-turn-helix domain
HEPIINGN_02099 2.53e-246 - - - L - - - Phage integrase, N-terminal SAM-like domain
HEPIINGN_02101 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEPIINGN_02102 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEPIINGN_02103 9.04e-171 radC - - L ko:K03630 - ko00000 Belongs to the UPF0758 family
HEPIINGN_02104 1.12e-241 rluC 5.4.99.24 - J ko:K06179 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEPIINGN_02105 0.0 - - - T - - - His Kinase A (phosphoacceptor) domain
HEPIINGN_02106 4.13e-167 - - - K - - - response regulator receiver
HEPIINGN_02107 4.72e-212 bcrA_2 - - V ko:K01990,ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEPIINGN_02108 3.52e-173 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEPIINGN_02109 6.59e-171 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_02110 4.73e-88 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEPIINGN_02111 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEPIINGN_02112 4.38e-209 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEPIINGN_02113 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEPIINGN_02114 1.57e-95 - - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEPIINGN_02115 2.19e-38 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEPIINGN_02116 6.8e-151 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEPIINGN_02117 4.68e-104 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02121 5.27e-64 - - - S - - - Stress responsive A/B Barrel Domain
HEPIINGN_02122 6.59e-52 - - - - - - - -
HEPIINGN_02123 1.29e-195 tatD - - L ko:K03424 - ko00000,ko01000 Hydrolase, TatD family
HEPIINGN_02124 3.41e-231 - - - EG - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02125 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEPIINGN_02126 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEPIINGN_02127 1.82e-144 - - - DV - - - (ABC) transporter
HEPIINGN_02128 3.35e-210 pgcA 5.4.2.2, 5.4.2.8 - G ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEPIINGN_02129 3.17e-94 - - - - - - - -
HEPIINGN_02130 4.89e-88 - - - - - - - -
HEPIINGN_02131 3.26e-36 - - - T - - - Nacht domain
HEPIINGN_02133 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEPIINGN_02134 3.02e-234 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEPIINGN_02135 1.39e-109 - - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEPIINGN_02136 1.06e-37 - - - S - - - Polysaccharide pyruvyl transferase
HEPIINGN_02137 1.91e-39 - - - C - - - Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HEPIINGN_02139 4.35e-91 - - - M - - - transferase activity, transferring glycosyl groups
HEPIINGN_02140 2.54e-109 - - - M - - - Glycosyltransferase, group 1 family protein
HEPIINGN_02141 9.82e-174 - - - M - - - Glycosyltransferase, group 1 family protein
HEPIINGN_02142 1.08e-132 - 2.7.8.6 - M ko:K00996 - ko00000,ko01000,ko01005 sugar transferase
HEPIINGN_02143 1.79e-107 - - - L - - - domain protein
HEPIINGN_02145 7.93e-151 - - - M - - - Domain of unknown function (DUF4367)
HEPIINGN_02146 1.69e-119 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_02147 4.48e-153 - - - K ko:K03086,ko:K03091 - ko00000,ko03021 Sigma-70 region 2
HEPIINGN_02148 1.24e-81 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_02149 2.56e-75 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_02150 9.84e-138 - - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 DNA primase activity
HEPIINGN_02151 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4 family
HEPIINGN_02152 3.69e-266 - - - D - - - Psort location Cytoplasmic, score
HEPIINGN_02153 3.61e-33 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02154 7.13e-52 - - - - - - - -
HEPIINGN_02156 2.32e-300 pfp 2.7.1.11, 2.7.1.90 - H ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HEPIINGN_02157 3.65e-291 pfp 2.7.1.11, 2.7.1.90 - H ko:K21071 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HEPIINGN_02158 2.29e-231 - - - E - - - GDSL-like Lipase/Acylhydrolase family
HEPIINGN_02160 5.15e-33 - - - S - - - ABC-2 family transporter protein
HEPIINGN_02161 1.69e-196 - - - V ko:K01990 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HEPIINGN_02162 4.06e-81 - - - K ko:K07979 - ko00000,ko03000 helix_turn_helix gluconate operon transcriptional repressor
HEPIINGN_02163 6.57e-297 dapL 2.6.1.83 - H ko:K10206 ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HEPIINGN_02164 1.31e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEPIINGN_02165 6.35e-46 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEPIINGN_02166 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HEPIINGN_02167 1.81e-222 - - - G - - - Aldose 1-epimerase
HEPIINGN_02168 9.1e-261 - - - T - - - Histidine kinase
HEPIINGN_02169 3.14e-155 - - - T - - - Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEPIINGN_02170 3.46e-25 - - - - - - - -
HEPIINGN_02171 7.07e-196 - - - C - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02172 3.72e-185 - - - CO ko:K06196 - ko00000,ko02000 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HEPIINGN_02173 0.0 - - - M - - - peptidoglycan binding domain protein
HEPIINGN_02174 1.11e-171 - - - M - - - peptidoglycan binding domain protein
HEPIINGN_02175 2.77e-114 - - - C - - - Flavodoxin domain
HEPIINGN_02176 1.44e-228 - 1.1.1.29, 1.1.1.399, 1.1.1.95 - CH ko:K00018,ko:K00058 ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 D-isomer specific 2-hydroxyacid dehydrogenase
HEPIINGN_02178 5.25e-175 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HEPIINGN_02179 2.73e-86 ogt 2.1.1.63 - L ko:K00567 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HEPIINGN_02180 1.21e-205 - - - T - - - cheY-homologous receiver domain
HEPIINGN_02181 8.84e-43 - - - S - - - Protein conserved in bacteria
HEPIINGN_02182 2.3e-233 - - - O - - - SPFH Band 7 PHB domain protein
HEPIINGN_02183 2.46e-273 - 2.7.1.165 - G ko:K11529 ko00030,ko00260,ko00561,ko00630,ko00680,ko01100,ko01120,ko01130,ko01200,map00030,map00260,map00561,map00630,map00680,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 MOFRL family
HEPIINGN_02185 9.27e-292 - - - M - - - Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HEPIINGN_02187 1.67e-70 - - - S - - - No similarity found
HEPIINGN_02189 4.64e-27 - - - S - - - SGNH hydrolase-like domain, acetyltransferase AlgX
HEPIINGN_02190 0.0 - - - M ko:K19294 - ko00000 Psort location CytoplasmicMembrane, score
HEPIINGN_02192 2.68e-09 - 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HEPIINGN_02193 1e-22 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_02195 3.69e-187 comF - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HEPIINGN_02196 0.0 - - - F - - - S-layer homology domain
HEPIINGN_02197 1.33e-275 macB1 - - V ko:K02004 - ko00000,ko00002,ko02000 Efflux ABC transporter, permease protein
HEPIINGN_02198 1.75e-173 macB - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_02199 0.0 - - - M ko:K02005 - ko00000 Efflux transporter, RND family, MFP subunit
HEPIINGN_02200 1.54e-92 - - - S - - - NusG domain II
HEPIINGN_02201 0.0 - 1.3.5.1, 1.3.5.4 - C ko:K00239,ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HEPIINGN_02202 5.28e-237 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02203 6.64e-170 - - - C - - - Psort location Cytoplasmic, score
HEPIINGN_02204 2.17e-287 - - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HEPIINGN_02205 2.12e-293 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEPIINGN_02206 0.0 glyQS 6.1.1.14 - J ko:K01880 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of glycine to tRNA(Gly)
HEPIINGN_02207 0.0 - - - T - - - His Kinase A (phosphoacceptor) domain
HEPIINGN_02208 4.82e-190 fliY1 - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HEPIINGN_02209 1.6e-103 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEPIINGN_02210 0.0 - 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 PFAM DNA gyrase topoisomerase IV, subunit A
HEPIINGN_02211 0.0 - 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 DNA topoisomerase
HEPIINGN_02217 1.48e-106 - - - K - - - Acetyltransferase (GNAT) domain
HEPIINGN_02218 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEPIINGN_02219 2.41e-259 - - - S - - - Acyltransferase family
HEPIINGN_02220 2.02e-247 - - - M - - - transferase activity, transferring glycosyl groups
HEPIINGN_02221 1.2e-175 - - - S - - - Calcineurin-like phosphoesterase
HEPIINGN_02222 0.0 - 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEPIINGN_02223 2.19e-247 dmpA 3.4.11.19 - EQ ko:K01266 - ko00000,ko01000,ko01002 Peptidase family S58
HEPIINGN_02224 4.09e-306 - - - V - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02225 3.19e-245 - - - S - - - AI-2E family transporter
HEPIINGN_02226 0.0 - - - FG ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEPIINGN_02227 0.0 - - - T - - - Response regulator receiver domain protein
HEPIINGN_02228 1.9e-104 - - - F - - - Belongs to the 5'-nucleotidase family
HEPIINGN_02229 0.0 apeB 3.4.11.21 - E ko:K01267 - ko00000,ko01000,ko01002,ko04131 M18 family aminopeptidase
HEPIINGN_02230 0.0 NPD5_3681 - - E - - - amino acid
HEPIINGN_02231 2.58e-154 - - - K - - - FCD
HEPIINGN_02232 3.17e-111 hsp18 - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEPIINGN_02233 6.93e-64 - - - S - - - Protein of unknown function (DUF2500)
HEPIINGN_02234 8.14e-75 - - - - - - - -
HEPIINGN_02235 7.81e-89 - - - S - - - YjbR
HEPIINGN_02236 3.86e-191 - - - S - - - HAD hydrolase, family IIB
HEPIINGN_02237 3.14e-194 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HEPIINGN_02238 1.28e-10 - - - T - - - Histidine kinase
HEPIINGN_02241 0.0 - - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02242 3.27e-191 - - - J - - - SpoU rRNA Methylase family
HEPIINGN_02244 3.38e-233 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_02246 1.3e-38 - - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_02247 6.81e-140 - - - K - - - DNA binding
HEPIINGN_02248 1.86e-146 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_02250 7.34e-64 - - - K - - - PFAM helix-turn-helix domain protein
HEPIINGN_02252 9.67e-76 - - - K - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02254 6.68e-71 - - - KT - - - COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HEPIINGN_02256 1.47e-154 - - - S ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HEPIINGN_02257 4.59e-175 - - - CP ko:K01992,ko:K19310 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HEPIINGN_02258 1.26e-216 - - - V ko:K01990,ko:K19309 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEPIINGN_02259 1.9e-205 - - - T - - - ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEPIINGN_02260 4.66e-164 - - - T - - - Transcriptional regulatory protein, C terminal
HEPIINGN_02261 1.11e-41 - - - K - - - Helix-turn-helix domain
HEPIINGN_02262 4.85e-71 mod 2.1.1.72 - L ko:K07316 - ko00000,ko01000,ko02048 PFAM DNA methylase N-4 N-6 domain protein
HEPIINGN_02263 6.62e-294 - - - U - - - Relaxase mobilization nuclease domain protein
HEPIINGN_02265 1.38e-66 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02266 0.0 - - - L - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02267 0.0 - - - D - - - MobA MobL family protein
HEPIINGN_02268 3.35e-15 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02269 1.05e-293 - - - T - - - GHKL domain
HEPIINGN_02270 5.43e-167 - - - K - - - cheY-homologous receiver domain
HEPIINGN_02271 1.43e-226 - - - - - - - -
HEPIINGN_02272 5.91e-85 - - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_02273 6.05e-53 - - - - - - - -
HEPIINGN_02274 1.65e-269 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02276 0.0 - - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HEPIINGN_02277 1.3e-104 - - - - - - - -
HEPIINGN_02279 4.75e-91 - 1.15.1.2 - C ko:K05919 - ko00000,ko01000 Superoxide reductase
HEPIINGN_02280 1.2e-238 - - - T - - - domain protein
HEPIINGN_02281 1.08e-22 - - - O - - - ADP-ribosylglycohydrolase
HEPIINGN_02282 1.4e-154 nnrE 5.1.99.6 - G ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HEPIINGN_02283 4.35e-238 - - - S - - - domain protein
HEPIINGN_02285 9.79e-183 - - - C - - - 4Fe-4S binding domain
HEPIINGN_02286 1.02e-187 - - - S - - - Putative cyclase
HEPIINGN_02287 7.52e-36 ywhH - - S ko:K03976 - ko00000,ko01000,ko03016 Cys-tRNA(Pro) hydrolase activity
HEPIINGN_02288 5.47e-196 - - - - - - - -
HEPIINGN_02289 1.73e-174 gufA - - P ko:K07238 - ko00000,ko02000 Metal cation transporter, ZIP family
HEPIINGN_02290 7.57e-145 - - - Q ko:K15256 - ko00000,ko01000,ko03016 Methyltransferase domain protein
HEPIINGN_02291 2.71e-197 - - - H - - - Leucine carboxyl methyltransferase
HEPIINGN_02292 2.67e-06 - - - S - - - L-2-amino-thiazoline-4-carboxylic acid hydrolase
HEPIINGN_02293 4.87e-244 - - - P - - - Citrate transporter
HEPIINGN_02294 2.11e-200 - - - S ko:K07088 - ko00000 Transporter, auxin efflux carrier (AEC) family protein
HEPIINGN_02295 8.98e-316 - - - P ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HEPIINGN_02296 2.08e-210 - - - K - - - LysR substrate binding domain protein
HEPIINGN_02297 1.45e-232 - - - G - - - TRAP transporter solute receptor, DctP family
HEPIINGN_02298 2.7e-281 - - - G - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02299 9.27e-121 - - - G - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02300 9.93e-245 - - - G - - - TRAP transporter solute receptor, DctP family
HEPIINGN_02301 2.03e-179 - - - K - - - Response regulator receiver domain
HEPIINGN_02302 0.0 - - - T - - - Histidine kinase
HEPIINGN_02303 9.41e-155 - - - K - - - Cyclic nucleotide-binding domain protein
HEPIINGN_02304 1.52e-153 - - - C - - - 4Fe-4S binding domain protein
HEPIINGN_02305 0.0 - - - T - - - Response regulator receiver domain protein
HEPIINGN_02306 3.8e-278 - - - T - - - Response regulator receiver domain protein
HEPIINGN_02307 1.23e-47 - - - S - - - RNHCP domain
HEPIINGN_02308 2.82e-183 yoaP - - E - - - YoaP-like
HEPIINGN_02309 1.09e-122 - - - K - - - Acetyltransferase GNAT family
HEPIINGN_02310 2.39e-184 - - - S - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HEPIINGN_02311 0.0 - - - T - - - Response regulator receiver domain protein
HEPIINGN_02312 0.0 - - - KT - - - transcriptional regulator LuxR family
HEPIINGN_02313 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 COG COG1653 ABC-type sugar transport system, periplasmic component
HEPIINGN_02317 0.0 - - - - - - - -
HEPIINGN_02318 0.0 - - - - - - - -
HEPIINGN_02320 2.67e-297 - - - S - - - SPFH domain-Band 7 family
HEPIINGN_02321 9.58e-211 - - - S - - - Domain of unknown function (DUF4428)
HEPIINGN_02323 3.33e-267 - - - K - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_02324 7.8e-166 - - - S ko:K06872 - ko00000 Pfam:TPM
HEPIINGN_02326 6.62e-133 - - - - - - - -
HEPIINGN_02328 1.66e-246 - - - - - - - -
HEPIINGN_02329 0.0 - 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01119,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HEPIINGN_02330 3.34e-277 - - - S - - - Leucine-rich repeat (LRR) protein
HEPIINGN_02331 3.16e-45 - - - S - - - Leucine-rich repeat (LRR) protein
HEPIINGN_02332 2.02e-140 - - - O - - - ATPase family associated with various cellular activities (AAA)
HEPIINGN_02333 0.0 - - - O - - - Subtilase family
HEPIINGN_02335 1.99e-203 - - - S - - - Replication initiator protein A
HEPIINGN_02336 2.68e-158 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HEPIINGN_02337 2.96e-195 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEPIINGN_02339 4.23e-05 - - - D - - - MobA MobL family protein
HEPIINGN_02340 1.8e-90 - - - S - - - Domain of unknown function (DUF3846)
HEPIINGN_02341 1.53e-60 - - - S - - - Protein of unknown function (DUF3801)
HEPIINGN_02342 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_02343 5.19e-27 - - - S - - - Maff2 family
HEPIINGN_02344 1.94e-59 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEPIINGN_02345 4.19e-84 - - - S - - - Transposon-encoded protein TnpV
HEPIINGN_02346 1.32e-121 - - - J ko:K19545 - ko00000,ko01504 Aminoglycoside-2''-adenylyltransferase
HEPIINGN_02347 9.72e-185 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_02348 1.85e-40 - - - - - - - -
HEPIINGN_02349 2.97e-76 - - - K - - - DeoR-like helix-turn-helix domain
HEPIINGN_02350 1.17e-57 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02353 0.0 - - - D - - - MobA MobL family protein
HEPIINGN_02354 8.4e-150 - - - L - - - CHC2 zinc finger domain protein
HEPIINGN_02355 0.0 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02356 4.61e-40 - - - - - - - -
HEPIINGN_02357 0.0 - - - L - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_02358 1.44e-196 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02359 2.36e-81 - - - S - - - PrgI family protein
HEPIINGN_02360 0.0 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_02361 0.0 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HEPIINGN_02363 2.56e-133 - - - S - - - Domain of unknown function (DUF4366)
HEPIINGN_02364 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_02365 2.69e-294 - - - DL - - - Involved in chromosome partitioning
HEPIINGN_02366 2.01e-35 - - - S - - - Putative tranposon-transfer assisting protein
HEPIINGN_02367 1.48e-165 - 1.1.1.304, 1.1.1.69, 1.1.1.76 - IQ ko:K00046,ko:K18009 ko00650,map00650 ko00000,ko00001,ko01000 Psort location Cytoplasmic, score
HEPIINGN_02368 6.44e-72 - - - - - - - -
HEPIINGN_02369 1.01e-68 - - - S - - - Protein of unknown function (DUF2500)
HEPIINGN_02370 7.77e-177 - - - S - - - AAA domain
HEPIINGN_02371 7.27e-197 - - - M - - - Psort location Cytoplasmic, score
HEPIINGN_02372 1.12e-47 - - - - - - - -
HEPIINGN_02373 2.61e-58 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02374 5.57e-60 - - - S - - - Transposon-encoded protein TnpV
HEPIINGN_02377 0.0 - - - D - - - MobA MobL family protein
HEPIINGN_02378 4.27e-21 - - - S - - - Protein of unknown function (DUF3847)
HEPIINGN_02379 8.59e-116 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_02380 3.04e-165 - - - M - - - Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HEPIINGN_02381 8.69e-167 - - - - - - - -
HEPIINGN_02382 5.33e-219 - - - E - - - Belongs to the peptidase S1B family
HEPIINGN_02384 2.35e-45 - - - - - - - -
HEPIINGN_02385 7.75e-65 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_02386 1.34e-126 - - - S - - - Domain of unknown function (DUF4366)
HEPIINGN_02388 0.0 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HEPIINGN_02389 4.91e-112 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_02390 0.0 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_02391 1.67e-79 - - - S - - - PrgI family protein
HEPIINGN_02392 4.13e-196 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02393 2.36e-38 - - - S - - - Maff2 family
HEPIINGN_02394 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_02395 0.0 - - - L - - - Protein of unknown function (DUF3991)
HEPIINGN_02396 5.32e-168 - - - D - - - MobA MobL family protein
HEPIINGN_02399 2.4e-20 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02400 1.28e-173 ermA 2.1.1.184 - J ko:K00561 - br01600,ko00000,ko01000,ko01504,ko03009 Ribosomal RNA adenine dimethylase
HEPIINGN_02401 1.37e-122 - - - L - - - Resolvase, N-terminal domain protein
HEPIINGN_02402 9.54e-52 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02403 5.51e-24 - - - S - - - Transposon-encoded protein TnpW
HEPIINGN_02404 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_02405 5.82e-60 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_02406 2.24e-101 - - - S - - - Protein of unknown function (DUF3801)
HEPIINGN_02407 1.32e-97 - - - S - - - Domain of unknown function (DUF3846)
HEPIINGN_02408 2.56e-07 - - - D - - - MobA MobL family protein
HEPIINGN_02410 5.65e-204 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEPIINGN_02411 3.36e-185 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HEPIINGN_02412 1.37e-190 - - - S - - - Replication initiator protein A domain protein
HEPIINGN_02413 3.13e-309 - - - P ko:K03498 - ko00000,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02414 2.71e-151 ktrA - - C ko:K03499 - ko00000,ko02000 system potassium uptake protein
HEPIINGN_02415 1.72e-244 kdpD 2.7.13.3 - T ko:K07646 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 ATPase histidine kinase DNA gyrase B HSP90 domain protein
HEPIINGN_02416 5.66e-168 kdpE - - K ko:K07667 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 transcriptional regulatory protein KdpE
HEPIINGN_02417 2.02e-278 - - - M - - - Phosphotransferase enzyme family
HEPIINGN_02418 7.56e-208 - - - K - - - transcriptional regulator AraC family
HEPIINGN_02419 1.06e-313 - - - G ko:K10200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Carbohydrate ABC transporter
HEPIINGN_02420 3.7e-202 - - - P ko:K10201 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02421 9.1e-205 - - - P ko:K10202 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02422 1.13e-32 - - - - - - - -
HEPIINGN_02423 0.0 gnpA 2.4.1.211 - S ko:K15533 - ko00000,ko01000 Lacto-N-biose phosphorylase C-terminal domain
HEPIINGN_02424 0.0 lacZ 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HEPIINGN_02425 0.0 - - - G ko:K03292 - ko00000 Transporter, major facilitator family protein
HEPIINGN_02426 4.86e-199 araC_2 - - K ko:K02099 - ko00000,ko03000 transcriptional regulator AraC family
HEPIINGN_02428 1.83e-111 - - - K - - - Acetyltransferase (GNAT) domain
HEPIINGN_02429 5.3e-301 - - - Q - - - Amidohydrolase family
HEPIINGN_02430 0.0 comM - - O ko:K07391 - ko00000 chelatase subunit ChlI
HEPIINGN_02432 0.0 pgcA 5.4.2.2, 5.4.2.8 - G ko:K01835,ko:K01840 ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEPIINGN_02433 3.63e-270 ispF 2.7.7.60, 4.6.1.12 - H ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HEPIINGN_02434 1.11e-206 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEPIINGN_02435 2.74e-302 - - - S - - - YbbR-like protein
HEPIINGN_02436 0.0 - - - S ko:K07137 - ko00000 FAD dependent oxidoreductase
HEPIINGN_02437 1.76e-300 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEPIINGN_02438 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 exonuclease
HEPIINGN_02439 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEPIINGN_02440 9.11e-106 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEPIINGN_02441 4.21e-150 - - - S - - - Metallo-beta-lactamase domain protein
HEPIINGN_02442 0.0 hemZ - - C - - - Coproporphyrinogen dehydrogenase
HEPIINGN_02443 1.09e-223 - 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Phosphoribulokinase uridine kinase family
HEPIINGN_02444 7.52e-72 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02445 4.09e-121 mazG 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 MazG family
HEPIINGN_02446 7.71e-52 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEPIINGN_02447 1.93e-46 hslR - - J - - - S4 domain protein
HEPIINGN_02448 1.62e-08 yabP - - S - - - Sporulation protein YabP
HEPIINGN_02449 6.24e-90 - - - - - - - -
HEPIINGN_02450 4.49e-61 - - - D ko:K13052 - ko00000,ko03036 septum formation initiator
HEPIINGN_02451 6.08e-88 yugI - - J ko:K07570,ko:K07571 - ko00000 S1 RNA binding domain
HEPIINGN_02452 1.73e-289 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HEPIINGN_02453 1.07e-203 - - - - - - - -
HEPIINGN_02454 6.76e-119 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02455 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEPIINGN_02456 0.0 - - - N - - - Bacterial Ig-like domain 2
HEPIINGN_02457 8.44e-244 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
HEPIINGN_02458 1.25e-102 - - - KT - - - Transcriptional regulator
HEPIINGN_02459 0.0 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin transporter
HEPIINGN_02461 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HEPIINGN_02462 0.0 - - - J ko:K07576 - ko00000 Metallo-beta-lactamase domain protein
HEPIINGN_02465 1.25e-85 - - - S - - - Bacterial PH domain
HEPIINGN_02466 0.0 - 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Beta-lactamase class C
HEPIINGN_02467 4.05e-266 - - - G - - - Major Facilitator
HEPIINGN_02468 1.4e-242 - - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HEPIINGN_02469 3.72e-132 ribU - - S - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEPIINGN_02470 0.0 - - - V - - - MATE efflux family protein
HEPIINGN_02471 2.76e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Glycosyl transferase family 4
HEPIINGN_02472 1.83e-198 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEPIINGN_02473 7.93e-133 fchA - - E - - - Formiminotransferase-cyclodeaminase
HEPIINGN_02474 2.75e-125 ygfA 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEPIINGN_02475 1.78e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEPIINGN_02476 4.18e-113 btuR 2.5.1.17 - H ko:K19221 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 cob(I)yrinic acid a,c-diamide adenosyltransferase
HEPIINGN_02477 0.0 dinG 3.1.12.1, 3.6.4.12 - L ko:K07464,ko:K10844 ko03022,ko03420,map03022,map03420 ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400 HELICc2
HEPIINGN_02478 8.06e-258 - - - LO - - - Psort location Cytoplasmic, score
HEPIINGN_02479 4.43e-140 udgA 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HEPIINGN_02480 5.05e-235 pta 2.3.1.8 - C ko:K00625 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 PFAM Phosphate acetyl butaryl transferase
HEPIINGN_02482 5.35e-215 - - - S - - - CAAX protease self-immunity
HEPIINGN_02483 5.4e-63 - - - S - - - Putative heavy-metal-binding
HEPIINGN_02484 1.96e-145 - - - K - - - helix_turn_helix, mercury resistance
HEPIINGN_02485 1.59e-288 cshA 3.6.4.13 - L ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 Belongs to the DEAD box helicase family
HEPIINGN_02486 5.07e-62 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 bacterial (prokaryotic) histone like domain
HEPIINGN_02487 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEPIINGN_02488 8.28e-275 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HEPIINGN_02489 3.09e-139 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEPIINGN_02490 4.4e-217 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEPIINGN_02491 1.64e-191 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HEPIINGN_02492 4.37e-207 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the OMP decarboxylase family. Type 2 subfamily
HEPIINGN_02493 5.84e-296 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEPIINGN_02495 1.02e-159 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 serine O-acetyltransferase
HEPIINGN_02496 0.0 - - - T ko:K07814 - ko00000,ko02022 HD domain
HEPIINGN_02498 3.77e-253 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEPIINGN_02499 4.44e-308 murA2 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HEPIINGN_02500 8.84e-236 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEPIINGN_02501 0.0 spoVD 3.4.16.4 - M ko:K03587,ko:K08384 ko00550,ko01501,map00550,map01501 ko00000,ko00001,ko01000,ko01011,ko03036 Penicillin-binding Protein
HEPIINGN_02502 4.05e-135 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEPIINGN_02503 5.99e-210 - - - S - - - Phospholipase, patatin family
HEPIINGN_02504 4.31e-63 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEPIINGN_02505 5.93e-113 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEPIINGN_02506 1.68e-157 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEPIINGN_02507 2.8e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEPIINGN_02508 8.66e-130 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HEPIINGN_02509 4.49e-46 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEPIINGN_02510 1.26e-28 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEPIINGN_02511 4.39e-268 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HEPIINGN_02512 5.7e-196 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEPIINGN_02513 3.78e-96 - - - S - - - Domain of unknown function (DUF1934)
HEPIINGN_02514 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HEPIINGN_02515 2.76e-247 dus - - H ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEPIINGN_02516 2.97e-136 yfbR 3.1.3.89 - S ko:K07023,ko:K08722 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 PFAM metal-dependent phosphohydrolase HD sub domain
HEPIINGN_02517 0.0 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02518 1.12e-230 - - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter substrate binding protein
HEPIINGN_02519 1.05e-202 - - - P ko:K05832 - ko00000,ko00002,ko02000 Branched-chain amino acid ABC transporter, permease protein
HEPIINGN_02520 3.12e-183 - - - S ko:K05833 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score
HEPIINGN_02521 4.33e-139 - - - S - - - Cytoplasmic, score 8.87
HEPIINGN_02522 1.63e-154 - - - K - - - FCD
HEPIINGN_02523 1.05e-117 - - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEPIINGN_02524 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 asparagine synthase (glutamine-hydrolyzing)
HEPIINGN_02525 0.0 fusA2 - - J ko:K02355 - ko00000,ko03012,ko03029 translation elongation
HEPIINGN_02527 1.28e-117 - 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 Cytidine and deoxycytidylate deaminase zinc-binding region
HEPIINGN_02528 1.85e-241 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEPIINGN_02529 3.61e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEPIINGN_02532 3.63e-115 - - - K ko:K03088 - ko00000,ko03021 Putative ATPase subunit of terminase (gpP-like)
HEPIINGN_02533 1.71e-217 - - - M - - - Domain of unknown function (DUF4349)
HEPIINGN_02534 1.15e-200 - - - IQ - - - short chain dehydrogenase
HEPIINGN_02536 1.33e-41 - - - K - - - Transcriptional regulator
HEPIINGN_02537 3.07e-120 - - - K ko:K03088 - ko00000,ko03021 Sigma-70, region 4
HEPIINGN_02539 1.25e-204 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEPIINGN_02540 2.55e-287 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02541 1.04e-199 - - - L - - - DNA binding domain of tn916 integrase
HEPIINGN_02542 1.69e-51 - - - S - - - Excisionase from transposon Tn916
HEPIINGN_02543 2.54e-162 - - - L - - - Virulence-associated protein E
HEPIINGN_02544 2.19e-116 - - - L - - - Virulence-associated protein E
HEPIINGN_02545 1.27e-179 - - - S - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02546 5.37e-37 - - - L - - - DNA helicase
HEPIINGN_02547 7e-49 - - - - - - - -
HEPIINGN_02548 1.39e-182 - - - S - - - Protein of unknown function (DUF1016)
HEPIINGN_02549 1.74e-175 - - - L - - - Phage integrase family
HEPIINGN_02550 2.26e-34 - - - S - - - Excisionase from transposon Tn916
HEPIINGN_02551 1.13e-269 - - - L - - - Virulence-associated protein E
HEPIINGN_02552 1.62e-195 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_02553 1.71e-18 - - - S - - - Bacterial mobilisation protein (MobC)
HEPIINGN_02554 1.89e-88 - - - V - - - Type I restriction
HEPIINGN_02555 2.74e-147 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_02556 5.69e-115 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain protein
HEPIINGN_02557 6.07e-302 hsdM 2.1.1.72 - L ko:K03427 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HEPIINGN_02558 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HEPIINGN_02559 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEPIINGN_02560 2.97e-99 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEPIINGN_02561 6.97e-157 - - - E - - - Psort location Cytoplasmic, score
HEPIINGN_02562 6.37e-206 - 2.7.1.2 - GK ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 ROK family
HEPIINGN_02563 2.58e-163 nanE 5.1.3.9 - G ko:K01788 ko00520,map00520 ko00000,ko00001,ko01000 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HEPIINGN_02564 4.93e-108 - - - G - - - Domain of unknown function (DUF386)
HEPIINGN_02565 6.04e-220 nanA 4.1.3.3 - EM ko:K01639 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the DapA family
HEPIINGN_02566 1.32e-221 - - - P ko:K02026 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02567 6.58e-214 - - - P ko:K02025 - ko00000,ko00002,ko02000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02568 0.0 - - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HEPIINGN_02569 3.01e-190 - - - K - - - Helix-turn-helix domain, rpiR family
HEPIINGN_02570 1.26e-154 - - - S ko:K06890 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02571 1.78e-265 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HEPIINGN_02572 1.49e-300 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_02574 2.12e-114 - - - K - - - WYL domain
HEPIINGN_02576 0.0 - - - S - - - Domain of unknown function DUF87
HEPIINGN_02578 7.67e-80 - - - K - - - Helix-turn-helix domain
HEPIINGN_02579 0.0 cas3 - - L ko:K07012 - ko00000,ko01000,ko02048 CRISPR-associated helicase, Cas3
HEPIINGN_02580 0.0 casA - - L ko:K19123 - ko00000,ko02048 CRISPR system CASCADE complex protein CasA
HEPIINGN_02581 1.46e-145 - - - S ko:K19046 - ko00000,ko02048 CRISPR-associated protein Cse2 (CRISPR_cse2)
HEPIINGN_02582 3.04e-237 casC - - L ko:K19124 - ko00000,ko02048 CRISPR system CASCADE complex protein CasC
HEPIINGN_02583 2.14e-155 casD - - S ko:K19125 - ko00000,ko02048 CRISPR-associated protein (Cas_Cas5)
HEPIINGN_02584 1.91e-144 casE - - S ko:K19126 - ko00000,ko02048 CRISPR_assoc
HEPIINGN_02585 4.68e-16 cas2 - - L ko:K09951 - ko00000,ko02048 K02342 DNA polymerase III subunit epsilon
HEPIINGN_02587 0.0 metH 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Psort location Cytoplasmic, score
HEPIINGN_02588 3.82e-158 metH2 2.1.1.13 - E ko:K00548 ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Vitamin B12 dependent methionine synthase activation
HEPIINGN_02589 8.56e-225 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_02590 7.18e-07 - - - K - - - transcriptional regulator, XRE family
HEPIINGN_02591 1.25e-22 - - - K - - - Cro/C1-type HTH DNA-binding domain
HEPIINGN_02594 3.74e-39 - - - L - - - DnaD domain protein
HEPIINGN_02595 5.57e-37 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEPIINGN_02598 1.25e-47 - - - - - - - -
HEPIINGN_02599 1.08e-17 - - - S - - - Domain of unknown function (DUF4258)
HEPIINGN_02601 2.7e-315 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_02602 8.45e-172 - - - K - - - helix_turn_helix, arabinose operon control protein
HEPIINGN_02603 4.85e-284 rhaB 2.7.1.5 - H ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Carbohydrate kinase, FGGY family protein
HEPIINGN_02604 0.0 - - - G - - - Catalyzes the conversion of L-arabinose to L-ribulose
HEPIINGN_02605 3.87e-199 rhaD 4.1.2.19 - H ko:K01629 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HEPIINGN_02606 0.0 - 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HEPIINGN_02607 2.27e-260 - - - G - - - alpha-L-rhamnosidase
HEPIINGN_02608 9.65e-176 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HEPIINGN_02609 2.35e-74 - - - K - - - AraC-like ligand binding domain
HEPIINGN_02611 6.87e-50 - - - - - - - -
HEPIINGN_02613 1.85e-69 - - - T - - - Hpt domain
HEPIINGN_02614 5.74e-240 - 1.1.1.79, 1.1.1.81 - EH ko:K12972 ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HEPIINGN_02615 1.55e-72 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
HEPIINGN_02616 0.0 glnS 6.1.1.18 - J ko:K01886 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glutaminyl-tRNA synthetase
HEPIINGN_02617 4.7e-205 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02618 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HEPIINGN_02619 0.0 - 1.1.1.17, 1.1.1.58 - C ko:K00009,ko:K00041 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Mannitol dehydrogenase
HEPIINGN_02620 0.0 uxaA 4.2.1.7 - G ko:K01685 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 SAF domain protein
HEPIINGN_02622 2.68e-224 - - - G - - - Aldose 1-epimerase
HEPIINGN_02623 2e-85 - - - L - - - Dinitrogenase iron-molybdenum cofactor
HEPIINGN_02624 1.89e-184 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02625 1.2e-207 - - - K - - - LysR substrate binding domain protein
HEPIINGN_02626 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEPIINGN_02627 6.85e-207 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HEPIINGN_02629 5.84e-224 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEPIINGN_02630 2.72e-274 cca 2.7.7.19, 2.7.7.72 - J ko:K00970,ko:K00974 ko03013,ko03018,map03013,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 tRNA nucleotidyltransferase poly(A) polymerase
HEPIINGN_02631 1.17e-269 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEPIINGN_02632 3.84e-185 thiF - - H ko:K22132 - ko00000,ko03016 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HEPIINGN_02633 6.63e-201 - - - S ko:K07089 - ko00000 Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02634 7.33e-220 - - - S - - - haloacid dehalogenase-like hydrolase
HEPIINGN_02635 1.05e-113 - 3.2.2.28 - L ko:K03649 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 UreE urease accessory protein, C-terminal domain
HEPIINGN_02636 1.82e-137 - - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HEPIINGN_02637 5.81e-253 - - - P - - - Belongs to the TelA family
HEPIINGN_02638 2.53e-163 - - - - - - - -
HEPIINGN_02639 5.22e-84 - - - S ko:K06872 - ko00000 Pfam:TPM
HEPIINGN_02640 1.11e-282 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HEPIINGN_02641 3.46e-78 - 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
HEPIINGN_02642 5.77e-287 - - - S ko:K06923 - ko00000 ATPase (AAA superfamily)
HEPIINGN_02643 0.0 ilvB 2.2.1.6 - H ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 acetolactate synthase large subunit
HEPIINGN_02644 3.63e-124 ilvN 2.2.1.6 - E ko:K01653 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetolactate synthase small
HEPIINGN_02645 1.31e-245 ilvC 1.1.1.86 - H ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HEPIINGN_02646 0.0 ilvD 4.2.1.9 - EG ko:K01687 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the IlvD Edd family
HEPIINGN_02647 2.93e-159 cpsE - - M - - - sugar transferase
HEPIINGN_02649 7.39e-54 - - - - - - - -
HEPIINGN_02650 1.79e-33 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02651 9.66e-262 - - - D - - - Psort location Cytoplasmic, score
HEPIINGN_02652 0.0 - - - S ko:K06919 - ko00000 Phage plasmid primase, P4 family
HEPIINGN_02653 7.45e-135 - - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 DNA primase activity
HEPIINGN_02654 1.8e-184 - - - K - - - Helix-turn-helix XRE-family like proteins
HEPIINGN_02655 1.05e-151 - - - K ko:K03086,ko:K03091 - ko00000,ko03021 Sigma-70 region 2
HEPIINGN_02656 8.05e-118 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_02657 7.95e-171 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HEPIINGN_02658 1.69e-64 - - - K - - - Transcriptional regulator
HEPIINGN_02659 1.33e-168 - 1.1.1.346 - K ko:K06221 - ko00000,ko01000 aldo keto reductase
HEPIINGN_02660 1.28e-298 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the isocitrate and isopropylmalate dehydrogenases family
HEPIINGN_02661 2.87e-291 - 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 PFAM Aminotransferase class I and II
HEPIINGN_02662 3.41e-278 - - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEPIINGN_02663 6.35e-276 - - - C - - - Sodium:dicarboxylate symporter family
HEPIINGN_02664 3.86e-300 - - - S - - - Belongs to the UPF0597 family
HEPIINGN_02665 2.17e-81 TdcF 3.5.99.10 - J ko:K09022 - ko00000,ko01000 endoribonuclease L-PSP
HEPIINGN_02666 2.06e-144 - - - S - - - YheO-like PAS domain
HEPIINGN_02667 2.34e-159 - - - S - - - hydrolase of the alpha beta superfamily
HEPIINGN_02668 6.79e-95 - - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HEPIINGN_02669 1.41e-150 - - - - - - - -
HEPIINGN_02670 1.34e-201 - - - S - - - Replication initiator protein A
HEPIINGN_02671 1.71e-157 - - - D ko:K03496 - ko00000,ko03036,ko04812 CobQ CobB MinD ParA nucleotide binding domain protein
HEPIINGN_02672 8.45e-163 - - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEPIINGN_02675 2.22e-80 - - - S - - - Domain of unknown function (DUF3846)
HEPIINGN_02676 1.78e-59 - - - S - - - Protein of unknown function (DUF3801)
HEPIINGN_02677 0.0 - - - U ko:K03205 ko03070,map03070 ko00000,ko00001,ko00002,ko02044 Psort location Cytoplasmic, score
HEPIINGN_02678 3.96e-24 - - - S - - - Maff2 family
HEPIINGN_02679 1.01e-108 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_02680 7.08e-164 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02681 2.35e-112 - - - K - - - Sigma-70, region 4
HEPIINGN_02682 1.32e-39 - - - S - - - Helix-turn-helix domain
HEPIINGN_02683 1e-95 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02684 8.5e-87 - - - S - - - Bacterial mobilisation protein (MobC)
HEPIINGN_02685 0.0 - - - U - - - Psort location Cytoplasmic, score 8.96
HEPIINGN_02686 2.77e-45 - - - - - - - -
HEPIINGN_02687 9.24e-174 - - - L - - - Phage replisome organizer
HEPIINGN_02688 1.53e-207 - - - L ko:K02315 - ko00000,ko03032 DNA replication protein
HEPIINGN_02689 2.25e-37 - - - S - - - Transposon-encoded protein TnpW
HEPIINGN_02690 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_02691 3.39e-195 - - - S - - - Psort location CytoplasmicMembrane, score
HEPIINGN_02692 6.04e-82 - - - S - - - PrgI family protein
HEPIINGN_02693 0.0 - - - U - - - Psort location Cytoplasmic, score
HEPIINGN_02694 0.0 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC/P60 family
HEPIINGN_02696 1.05e-134 - - - S - - - Domain of unknown function (DUF4366)
HEPIINGN_02697 6.15e-62 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_02698 6.63e-73 - - - - - - - -
HEPIINGN_02703 1.47e-147 - - - M - - - Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HEPIINGN_02704 6.01e-104 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HEPIINGN_02705 2.27e-20 - - - S - - - Protein of unknown function (DUF3847)
HEPIINGN_02706 0.0 - - - D - - - MobA MobL family protein
HEPIINGN_02708 0.0 - - - L - - - Psort location Cytoplasmic, score
HEPIINGN_02709 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase III
HEPIINGN_02710 2.59e-294 - - - DL - - - Involved in chromosome partitioning
HEPIINGN_02711 1.89e-40 - - - S - - - Putative tranposon-transfer assisting protein
HEPIINGN_02712 2.85e-75 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Low molecular weight phosphotyrosine protein phosphatase
HEPIINGN_02715 4.65e-71 - - - S - - - Transposon-encoded protein TnpV
HEPIINGN_02718 3.49e-132 - - - T ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEPIINGN_02719 2.01e-36 - - - K - - - DNA binding
HEPIINGN_02721 7.87e-209 - - - D ko:K06381 - ko00000 sporulation resulting in formation of a cellular spore
HEPIINGN_02722 0.0 - - GT2,GT4 M ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyltransferase, group 2 family protein
HEPIINGN_02723 2.23e-192 - - GT2,GT4 M ko:K07011,ko:K20444 - ko00000,ko01000,ko01005,ko02000 Glycosyl transferase family 21
HEPIINGN_02724 2.66e-216 rfbA 2.7.7.24 - H ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HEPIINGN_02725 2.06e-234 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HEPIINGN_02727 1.31e-273 rfbB 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HEPIINGN_02728 1.21e-137 - - - F - - - Psort location Cytoplasmic, score
HEPIINGN_02729 1.17e-142 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02730 2.81e-36 feoA - - P ko:K04758 - ko00000,ko02000 Fe2 transport system protein A
HEPIINGN_02731 2.13e-44 feoA - - P ko:K04758 - ko00000,ko02000 Fe2 transport system protein A
HEPIINGN_02732 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HEPIINGN_02733 3.39e-17 - - - - - - - -
HEPIINGN_02734 1.55e-81 - - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HEPIINGN_02735 3.72e-224 envE 3.1.4.46, 3.2.1.18, 3.2.1.8 GH33 E ko:K01126,ko:K01181,ko:K01186 ko00511,ko00564,ko00600,ko04142,map00511,map00564,map00600,map04142 ko00000,ko00001,ko01000,ko02042 lipolytic protein G-D-S-L family
HEPIINGN_02736 0.0 - 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme
HEPIINGN_02737 1.41e-285 - - - C - - - 4Fe-4S dicluster domain
HEPIINGN_02738 1.98e-212 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEPIINGN_02739 0.0 - - - S - - - Psort location CytoplasmicMembrane, score 10.00
HEPIINGN_02740 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HEPIINGN_02741 0.0 - 3.2.1.133, 3.2.1.135, 3.2.1.54, 3.5.4.33 GH13 G ko:K01208,ko:K11991 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000,ko03016 Alpha amylase, catalytic domain protein
HEPIINGN_02742 2.23e-113 niaR - - S ko:K07105 - ko00000 3H domain
HEPIINGN_02743 1.57e-107 - - - K - - - Psort location Cytoplasmic, score
HEPIINGN_02744 0.0 - - - T - - - Diguanylate cyclase (GGDEF) domain protein
HEPIINGN_02745 3.24e-221 - - - S - - - Psort location Cytoplasmic, score
HEPIINGN_02746 5.55e-267 - - - S - - - domain protein
HEPIINGN_02747 6.18e-238 - - - S - - - Oxidoreductase family, NAD-binding Rossmann fold
HEPIINGN_02748 3.79e-250 ltaE 4.1.2.48 - E ko:K01620 ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 Beta-eliminating lyase
HEPIINGN_02750 6.71e-100 - - - L - - - domain protein
HEPIINGN_02751 2.36e-157 - - - M ko:K13012 - ko00000,ko01005 Bacterial sugar transferase
HEPIINGN_02752 5.94e-218 - - GT4 M ko:K13004 - ko00000,ko01000,ko01003,ko01005 Glycosyl transferase 4-like
HEPIINGN_02753 4.18e-29 - - - S - - - Hexapeptide repeat of succinyl-transferase
HEPIINGN_02754 7.72e-96 - - - M - - - Glycosyl transferases group 1
HEPIINGN_02755 1.11e-30 - - - M - - - transferase activity, transferring glycosyl groups
HEPIINGN_02756 2.92e-105 - - - S - - - Glycosyl transferase, family 2
HEPIINGN_02758 8.85e-244 capD 5.1.3.2 - M ko:K17716 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Polysaccharide biosynthesis protein
HEPIINGN_02759 3.16e-70 - - - M - - - Bacterial transferase hexapeptide (six repeats)
HEPIINGN_02760 1.32e-293 - 1.1.1.367 - GM ko:K19068 - ko00000,ko01000 NAD dependent epimerase/dehydratase family
HEPIINGN_02761 6.05e-293 wecB 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 UDP-N-acetylglucosamine 2-epimerase
HEPIINGN_02762 3.67e-254 lspL 5.1.3.6 - M ko:K08679 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 epimerase dehydratase
HEPIINGN_02763 4.74e-271 - 1.1.1.22 - C ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 UDP binding domain
HEPIINGN_02764 1.76e-178 cps4J - - S - - - Polysaccharide biosynthesis protein
HEPIINGN_02765 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEPIINGN_02768 5.04e-94 - - - - - - - -
HEPIINGN_02769 1.48e-112 - - - S - - - Psort location Cytoplasmic, score 8.87
HEPIINGN_02773 9.59e-95 - - - K - - - DNA-templated transcription, initiation
HEPIINGN_02774 2.27e-213 - - - S - - - TraX protein
HEPIINGN_02775 3.39e-155 - - - KT ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HEPIINGN_02776 2.96e-214 - 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HEPIINGN_02777 5.24e-231 - - - I - - - Hydrolase, alpha beta domain protein
HEPIINGN_02778 6.32e-55 - - - K ko:K06284 - ko00000,ko03000 Transcriptional regulator, AbrB family
HEPIINGN_02779 2.6e-281 - - - P - - - Transporter, CPA2 family
HEPIINGN_02780 3.39e-254 - - - S - - - Glycosyltransferase like family 2
HEPIINGN_02781 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HEPIINGN_02782 2.58e-141 nrdG 1.97.1.4 - C ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEPIINGN_02783 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HEPIINGN_02784 1.39e-258 - - - L - - - Belongs to the 'phage' integrase family
HEPIINGN_02785 3.32e-88 - - - L ko:K07491 - ko00000 PFAM transposase IS200-family protein
HEPIINGN_02786 7.68e-61 - - - L - - - RelB antitoxin
HEPIINGN_02790 7.84e-51 - - - L - - - Psort location Cytoplasmic, score

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)