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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
BIGNABAM_00001	4.37e-266	pepA	-	-	E	-	-	-	M42 glutamyl aminopeptidase
BIGNABAM_00002	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
BIGNABAM_00003	7.09e-222	ydhF	-	-	S	-	-	-	Aldo keto reductase
BIGNABAM_00004	2.61e-193	-	-	-	-	-	-	-	-
BIGNABAM_00005	3.24e-306	steT	-	-	E	ko:K03294	-	ko00000	amino acid
BIGNABAM_00006	2.92e-313	steT	-	-	E	ko:K03294	-	ko00000	amino acid
BIGNABAM_00007	2.62e-166	-	-	-	F	-	-	-	glutamine amidotransferase
BIGNABAM_00008	2.49e-189	peb1A	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BIGNABAM_00009	7.98e-35	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
BIGNABAM_00010	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00011	0.0	XK27_09605	-	-	V	ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter transmembrane region
BIGNABAM_00012	1.79e-131	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
BIGNABAM_00013	6.04e-242	-	-	-	G	-	-	-	MFS/sugar transport protein
BIGNABAM_00014	4.83e-51	-	-	-	G	-	-	-	MFS/sugar transport protein
BIGNABAM_00015	4.52e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Zeta toxin
BIGNABAM_00016	1.19e-174	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00017	3.16e-192	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00018	7.42e-123	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00019	3.65e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00020	1.07e-207	-	-	-	S	-	-	-	Protein of unknown function (DUF2974)
BIGNABAM_00021	4.55e-149	-	-	-	L	-	-	-	Resolvase, N-terminal
BIGNABAM_00022	0.0	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
BIGNABAM_00023	7.3e-111	-	-	-	-	-	-	-	-
BIGNABAM_00024	1.01e-295	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
BIGNABAM_00025	8.94e-308	srrA1	-	-	G	ko:K02027,ko:K17244	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGNABAM_00026	2.97e-208	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
BIGNABAM_00027	8.52e-215	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIGNABAM_00028	4.48e-162	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BIGNABAM_00029	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
BIGNABAM_00030	4.28e-224	rihC	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
BIGNABAM_00031	6.63e-174	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
BIGNABAM_00032	3.18e-198	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
BIGNABAM_00033	2.9e-79	-	-	-	S	-	-	-	Enterocin A Immunity
BIGNABAM_00034	1.88e-175	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
BIGNABAM_00035	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
BIGNABAM_00036	3.54e-194	-	-	-	S	-	-	-	Phospholipase, patatin family
BIGNABAM_00037	3.84e-191	-	-	-	S	-	-	-	hydrolase
BIGNABAM_00038	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
BIGNABAM_00039	1.62e-188	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
BIGNABAM_00040	1.52e-103	-	-	-	-	-	-	-	-
BIGNABAM_00041	1.96e-113	ptbA	2.7.1.208	-	G	ko:K02755,ko:K02777,ko:K20107,ko:K20108	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
BIGNABAM_00042	1.76e-52	-	-	-	-	-	-	-	-
BIGNABAM_00043	7.48e-155	-	-	-	C	-	-	-	nitroreductase
BIGNABAM_00044	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
BIGNABAM_00045	8.59e-133	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
BIGNABAM_00046	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
BIGNABAM_00047	4.43e-29	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
BIGNABAM_00048	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
BIGNABAM_00049	1.29e-295	-	-	-	E	ko:K03294	-	ko00000	amino acid
BIGNABAM_00050	4.31e-167	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
BIGNABAM_00051	2.83e-281	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
BIGNABAM_00052	9.4e-317	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_00054	1.62e-278	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
BIGNABAM_00055	3.7e-113	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
BIGNABAM_00056	5.14e-105	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
BIGNABAM_00057	2.45e-211	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
BIGNABAM_00058	9.85e-209	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
BIGNABAM_00059	1.6e-215	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
BIGNABAM_00060	7.39e-274	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
BIGNABAM_00061	1.05e-272	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
BIGNABAM_00062	3.54e-277	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
BIGNABAM_00063	7.74e-61	-	-	-	-	-	-	-	-
BIGNABAM_00064	3.81e-226	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
BIGNABAM_00065	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BIGNABAM_00066	1.38e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
BIGNABAM_00067	7.1e-111	-	-	-	-	-	-	-	-
BIGNABAM_00068	3.85e-98	-	-	-	-	-	-	-	-
BIGNABAM_00069	1.24e-181	hlyX	-	-	S	ko:K03699	-	ko00000,ko02042	Transporter associated domain
BIGNABAM_00070	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BIGNABAM_00071	5.93e-60	XK27_09445	-	-	S	-	-	-	Domain of unknown function (DUF1827)
BIGNABAM_00072	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
BIGNABAM_00073	2.6e-37	-	-	-	-	-	-	-	-
BIGNABAM_00074	1.29e-54	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
BIGNABAM_00075	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIGNABAM_00076	6.28e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BIGNABAM_00077	1.5e-178	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
BIGNABAM_00078	6.73e-208	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
BIGNABAM_00079	8.16e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
BIGNABAM_00080	4.21e-144	-	-	-	S	-	-	-	CYTH
BIGNABAM_00081	1.7e-147	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
BIGNABAM_00082	1.91e-195	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BIGNABAM_00083	2.19e-218	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BIGNABAM_00084	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
BIGNABAM_00085	2.66e-122	-	-	-	S	-	-	-	SNARE associated Golgi protein
BIGNABAM_00086	7.13e-256	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
BIGNABAM_00087	1.99e-87	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
BIGNABAM_00088	2.19e-270	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
BIGNABAM_00089	2.12e-136	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
BIGNABAM_00090	3.12e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1149)
BIGNABAM_00091	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
BIGNABAM_00092	2.83e-282	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
BIGNABAM_00093	5.49e-301	ymfH	-	-	S	-	-	-	Peptidase M16
BIGNABAM_00094	6.87e-172	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
BIGNABAM_00095	1.63e-154	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
BIGNABAM_00096	3.92e-123	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BIGNABAM_00097	8.51e-248	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BIGNABAM_00098	9.52e-75	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
BIGNABAM_00099	9.63e-202	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
BIGNABAM_00100	4.56e-267	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
BIGNABAM_00101	1.19e-152	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
BIGNABAM_00102	2.68e-314	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
BIGNABAM_00103	4.17e-172	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
BIGNABAM_00104	1.55e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BIGNABAM_00105	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
BIGNABAM_00106	3.19e-238	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BIGNABAM_00107	1.02e-27	-	-	-	-	-	-	-	-
BIGNABAM_00108	3.54e-230	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BIGNABAM_00109	8.14e-203	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BIGNABAM_00110	5.73e-240	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
BIGNABAM_00111	1.98e-231	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
BIGNABAM_00112	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
BIGNABAM_00113	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
BIGNABAM_00114	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
BIGNABAM_00115	1.88e-118	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
BIGNABAM_00116	2.44e-211	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
BIGNABAM_00117	2.78e-251	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
BIGNABAM_00118	8.59e-221	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
BIGNABAM_00119	1.16e-128	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
BIGNABAM_00120	0.0	-	-	-	S	-	-	-	SH3-like domain
BIGNABAM_00121	3.16e-144	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00122	5.56e-167	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
BIGNABAM_00123	4.77e-124	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
BIGNABAM_00124	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
BIGNABAM_00125	5.38e-101	-	-	-	K	-	-	-	MerR HTH family regulatory protein
BIGNABAM_00126	8.04e-185	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
BIGNABAM_00127	0.0	ycaM	-	-	E	-	-	-	amino acid
BIGNABAM_00128	0.0	-	-	-	-	-	-	-	-
BIGNABAM_00130	1.6e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
BIGNABAM_00131	2.86e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
BIGNABAM_00132	2.86e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
BIGNABAM_00133	5.46e-183	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
BIGNABAM_00134	3.07e-124	-	-	-	-	-	-	-	-
BIGNABAM_00135	8.06e-200	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
BIGNABAM_00136	6.67e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BIGNABAM_00137	4.68e-234	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
BIGNABAM_00138	5.86e-114	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
BIGNABAM_00139	8.73e-127	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
BIGNABAM_00140	4.91e-209	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
BIGNABAM_00141	1.25e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
BIGNABAM_00142	2.25e-175	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00143	3.69e-170	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00144	3.46e-266	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BIGNABAM_00145	2.13e-194	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BIGNABAM_00146	2.76e-221	ybbR	-	-	S	-	-	-	YbbR-like protein
BIGNABAM_00147	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BIGNABAM_00148	1.62e-189	-	-	-	S	-	-	-	hydrolase
BIGNABAM_00149	3.23e-98	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
BIGNABAM_00150	1.41e-153	-	-	-	-	-	-	-	-
BIGNABAM_00151	3.07e-112	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BIGNABAM_00152	4.36e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
BIGNABAM_00153	5.06e-196	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
BIGNABAM_00154	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
BIGNABAM_00155	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGNABAM_00156	1.98e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
BIGNABAM_00157	0.0	-	-	-	E	-	-	-	Amino acid permease
BIGNABAM_00159	4.8e-38	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BIGNABAM_00160	1.41e-142	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
BIGNABAM_00161	4.7e-120	-	-	-	S	-	-	-	VanZ like family
BIGNABAM_00162	5.65e-171	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
BIGNABAM_00163	5.04e-231	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
BIGNABAM_00164	5.15e-224	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
BIGNABAM_00165	7.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
BIGNABAM_00166	1.72e-92	-	-	-	-	ko:K02246	-	ko00000,ko00002,ko02044	-
BIGNABAM_00167	1.68e-55	-	-	-	-	-	-	-	-
BIGNABAM_00168	1.94e-100	-	-	-	U	ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
BIGNABAM_00169	3.69e-30	-	-	-	-	-	-	-	-
BIGNABAM_00170	4.37e-241	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
BIGNABAM_00171	2.51e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BIGNABAM_00173	3.01e-128	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
BIGNABAM_00174	3.88e-285	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
BIGNABAM_00175	2.74e-242	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
BIGNABAM_00176	9.01e-90	-	-	-	S	-	-	-	SdpI/YhfL protein family
BIGNABAM_00177	7.05e-167	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
BIGNABAM_00178	0.0	yclK	-	-	T	-	-	-	Histidine kinase
BIGNABAM_00179	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BIGNABAM_00180	5.3e-137	vanZ	-	-	V	-	-	-	VanZ like family
BIGNABAM_00181	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
BIGNABAM_00182	2.41e-276	-	-	-	EGP	-	-	-	Major Facilitator
BIGNABAM_00183	3.94e-250	ampC	-	-	V	-	-	-	Beta-lactamase
BIGNABAM_00186	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
BIGNABAM_00187	2.01e-145	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
BIGNABAM_00188	6.6e-237	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BIGNABAM_00189	1.51e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
BIGNABAM_00190	1.86e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
BIGNABAM_00191	5.28e-146	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BIGNABAM_00192	4.44e-161	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
BIGNABAM_00193	4.36e-39	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIGNABAM_00194	1.69e-86	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BIGNABAM_00195	2.67e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIGNABAM_00196	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BIGNABAM_00197	4.54e-216	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BIGNABAM_00198	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BIGNABAM_00199	5.78e-92	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
BIGNABAM_00200	1.52e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
BIGNABAM_00201	8.31e-228	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
BIGNABAM_00202	5.54e-69	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
BIGNABAM_00203	1.26e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
BIGNABAM_00204	2.05e-276	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
BIGNABAM_00205	3.06e-139	-	-	-	L	-	-	-	Transposase
BIGNABAM_00206	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	belongs to the glycosyl hydrolase 13 family
BIGNABAM_00207	1.83e-101	uspA	-	-	T	-	-	-	universal stress protein
BIGNABAM_00208	1.35e-56	-	-	-	-	-	-	-	-
BIGNABAM_00209	4.21e-302	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
BIGNABAM_00210	5.68e-110	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
BIGNABAM_00211	3.07e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BIGNABAM_00212	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
BIGNABAM_00213	2.58e-274	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
BIGNABAM_00214	3.89e-285	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BIGNABAM_00215	8.58e-122	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00216	1.33e-122	-	-	-	-	-	-	-	-
BIGNABAM_00217	7.88e-143	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00218	2.33e-286	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_00220	1.28e-312	-	-	-	L	-	-	-	Transposase
BIGNABAM_00221	0.0	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_00222	1.93e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF3232)
BIGNABAM_00223	1.23e-52	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_00224	4.99e-88	-	-	-	-	-	-	-	-
BIGNABAM_00225	4.85e-58	-	-	-	-	-	-	-	-
BIGNABAM_00226	2.47e-156	-	-	-	-	-	-	-	-
BIGNABAM_00227	2.1e-153	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BIGNABAM_00228	1.89e-48	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
BIGNABAM_00229	1.06e-86	-	-	-	S	-	-	-	GtrA-like protein
BIGNABAM_00230	1.22e-219	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
BIGNABAM_00231	3.33e-123	-	-	-	S	-	-	-	Protein of unknown function (DUF3990)
BIGNABAM_00232	2.09e-59	-	-	-	-	-	-	-	-
BIGNABAM_00233	3.84e-05	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
BIGNABAM_00234	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
BIGNABAM_00235	1.09e-222	-	-	-	-	-	-	-	-
BIGNABAM_00236	1.17e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_00237	1.83e-40	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_00238	9.17e-20	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
BIGNABAM_00239	5.17e-83	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
BIGNABAM_00240	5.85e-56	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00241	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
BIGNABAM_00242	1.27e-308	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
BIGNABAM_00243	3.17e-164	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
BIGNABAM_00244	1.07e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
BIGNABAM_00245	5.81e-226	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
BIGNABAM_00246	4.1e-189	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
BIGNABAM_00247	5.43e-122	mreD	-	-	-	ko:K03571	-	ko00000,ko03036	-
BIGNABAM_00248	1.4e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
BIGNABAM_00249	1.02e-72	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
BIGNABAM_00250	5.63e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
BIGNABAM_00251	4.45e-225	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
BIGNABAM_00252	6.55e-72	ftsL	-	-	D	-	-	-	Cell division protein FtsL
BIGNABAM_00253	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
BIGNABAM_00254	3.12e-224	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BIGNABAM_00255	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BIGNABAM_00256	1.16e-265	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BIGNABAM_00257	1.33e-195	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
BIGNABAM_00258	1.88e-310	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
BIGNABAM_00259	9.61e-305	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BIGNABAM_00260	1.43e-96	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
BIGNABAM_00261	2.42e-60	yggT	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
BIGNABAM_00262	5.69e-192	ylmH	-	-	S	-	-	-	S4 domain protein
BIGNABAM_00263	1.55e-138	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
BIGNABAM_00264	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BIGNABAM_00265	2.32e-43	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
BIGNABAM_00266	1.04e-133	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
BIGNABAM_00267	1.8e-57	-	-	-	-	-	-	-	-
BIGNABAM_00268	2.05e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BIGNABAM_00269	1.33e-275	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
BIGNABAM_00270	2.97e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
BIGNABAM_00271	1.9e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
BIGNABAM_00272	4.7e-163	pgm	-	-	G	-	-	-	Phosphoglycerate mutase family
BIGNABAM_00273	1.34e-147	-	-	-	S	-	-	-	repeat protein
BIGNABAM_00274	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
BIGNABAM_00275	0.0	-	-	-	L	-	-	-	Nuclease-related domain
BIGNABAM_00276	3.07e-235	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
BIGNABAM_00277	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BIGNABAM_00278	1.09e-46	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
BIGNABAM_00279	9.73e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
BIGNABAM_00280	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
BIGNABAM_00281	3.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
BIGNABAM_00282	9.94e-71	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
BIGNABAM_00283	5.21e-126	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
BIGNABAM_00284	7.07e-107	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BIGNABAM_00285	4.94e-245	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
BIGNABAM_00286	3.15e-125	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
BIGNABAM_00287	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
BIGNABAM_00288	1.49e-225	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
BIGNABAM_00289	6.28e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
BIGNABAM_00290	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BIGNABAM_00291	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BIGNABAM_00292	4.65e-192	-	-	-	-	-	-	-	-
BIGNABAM_00293	4.06e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BIGNABAM_00294	1.09e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
BIGNABAM_00295	3.04e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BIGNABAM_00296	9.2e-136	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
BIGNABAM_00297	1.32e-27	potE	-	-	E	-	-	-	Amino Acid
BIGNABAM_00298	2.35e-132	potE	-	-	E	-	-	-	Amino acid permease
BIGNABAM_00299	6.25e-246	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BIGNABAM_00300	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
BIGNABAM_00301	5.89e-314	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
BIGNABAM_00302	5.23e-106	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
BIGNABAM_00303	1.4e-281	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
BIGNABAM_00304	1.49e-224	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BIGNABAM_00305	6.89e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
BIGNABAM_00306	4.67e-279	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
BIGNABAM_00307	1.44e-253	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BIGNABAM_00308	4.2e-249	pbpX1	-	-	V	-	-	-	Beta-lactamase
BIGNABAM_00309	0.0	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
BIGNABAM_00310	1.83e-54	-	-	-	C	-	-	-	FMN_bind
BIGNABAM_00311	9.44e-110	-	-	-	-	-	-	-	-
BIGNABAM_00312	1.3e-164	iunH	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	inosine-uridine preferring nucleoside hydrolase
BIGNABAM_00313	2.89e-116	alkD	-	-	L	-	-	-	DNA alkylation repair enzyme
BIGNABAM_00314	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGNABAM_00315	3.83e-165	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
BIGNABAM_00316	1.32e-74	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
BIGNABAM_00317	7.88e-79	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
BIGNABAM_00318	2.1e-109	-	-	-	-	-	-	-	-
BIGNABAM_00319	1.74e-45	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_00320	1.9e-240	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_00321	4.04e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
BIGNABAM_00322	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGNABAM_00323	4.84e-171	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
BIGNABAM_00324	7.23e-55	-	-	-	-	-	-	-	-
BIGNABAM_00325	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_00326	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGNABAM_00327	5.95e-204	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
BIGNABAM_00328	7.07e-112	yfhC	-	-	C	-	-	-	nitroreductase
BIGNABAM_00329	9.43e-127	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
BIGNABAM_00330	3.52e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
BIGNABAM_00331	3.66e-189	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
BIGNABAM_00332	8.23e-132	-	-	-	I	-	-	-	PAP2 superfamily
BIGNABAM_00333	1.72e-243	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
BIGNABAM_00335	8.58e-228	-	-	-	S	-	-	-	Conserved hypothetical protein 698
BIGNABAM_00336	8.4e-112	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
BIGNABAM_00337	1.41e-05	-	1.3.99.4	-	C	ko:K05898	ko00984,ko01100,ko01120,map00984,map01100,map01120	ko00000,ko00001,ko01000	Succinate dehydrogenase fumarate reductase flavoprotein subunit
BIGNABAM_00338	8.71e-126	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
BIGNABAM_00339	1.3e-117	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
BIGNABAM_00340	2.74e-96	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
BIGNABAM_00341	1.32e-19	-	-	-	L	-	-	-	transposase activity
BIGNABAM_00342	5.14e-27	-	-	-	M	-	-	-	domain protein
BIGNABAM_00343	7.17e-112	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BIGNABAM_00344	7.34e-91	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BIGNABAM_00345	1.96e-51	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
BIGNABAM_00346	3.12e-95	-	-	-	K	-	-	-	LytTr DNA-binding domain
BIGNABAM_00347	7.36e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
BIGNABAM_00348	7.76e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
BIGNABAM_00349	9.37e-144	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	domain protein
BIGNABAM_00350	8.87e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_00351	1.52e-93	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BIGNABAM_00352	9.64e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
BIGNABAM_00353	8.69e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BIGNABAM_00354	7.54e-194	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K02029,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BIGNABAM_00355	3.01e-255	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
BIGNABAM_00356	1.14e-107	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
BIGNABAM_00357	1.75e-256	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
BIGNABAM_00358	6.17e-158	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BIGNABAM_00359	1.59e-141	yqeK	-	-	H	-	-	-	Hydrolase, HD family
BIGNABAM_00360	5.09e-78	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
BIGNABAM_00361	1.39e-276	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
BIGNABAM_00362	1.32e-126	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
BIGNABAM_00363	3.52e-163	csrR	-	-	K	-	-	-	response regulator
BIGNABAM_00364	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BIGNABAM_00365	2.66e-154	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
BIGNABAM_00366	1.78e-284	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_00367	7.36e-114	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
BIGNABAM_00368	6.97e-216	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BIGNABAM_00369	5.58e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
BIGNABAM_00370	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIGNABAM_00371	4.16e-82	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
BIGNABAM_00373	4.43e-143	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
BIGNABAM_00374	5.01e-151	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
BIGNABAM_00375	5.64e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00376	9.94e-209	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00377	3.39e-253	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BIGNABAM_00378	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BIGNABAM_00379	2.55e-94	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BIGNABAM_00380	8.21e-215	ldh3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	lactate/malate dehydrogenase, alpha/beta C-terminal domain
BIGNABAM_00381	5.5e-203	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
BIGNABAM_00382	1.05e-33	-	-	-	-	-	-	-	-
BIGNABAM_00383	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
BIGNABAM_00384	3.82e-188	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
BIGNABAM_00385	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
BIGNABAM_00386	7.62e-290	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
BIGNABAM_00387	8.37e-296	-	-	-	S	ko:K12941	-	ko00000,ko01002	Peptidase dimerisation domain
BIGNABAM_00388	1.12e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
BIGNABAM_00389	7.04e-108	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_00390	4.96e-63	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2263)
BIGNABAM_00391	6.13e-163	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_00392	6.09e-121	-	-	-	-	-	-	-	-
BIGNABAM_00394	4.96e-159	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
BIGNABAM_00395	1.45e-203	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
BIGNABAM_00396	1.39e-204	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BIGNABAM_00397	7.1e-177	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	abc transporter atp-binding protein
BIGNABAM_00398	2.22e-60	hupB2	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BIGNABAM_00399	7.04e-218	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
BIGNABAM_00400	0.0	-	-	-	S	-	-	-	membrane
BIGNABAM_00401	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
BIGNABAM_00402	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
BIGNABAM_00403	1.94e-126	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BIGNABAM_00404	2.29e-154	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Rhomboid family
BIGNABAM_00405	1e-47	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
BIGNABAM_00406	4.95e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
BIGNABAM_00407	1.98e-218	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BIGNABAM_00408	2.05e-286	ynbB	-	-	P	-	-	-	aluminum resistance
BIGNABAM_00409	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
BIGNABAM_00410	2.88e-220	-	-	-	-	-	-	-	-
BIGNABAM_00411	1.72e-204	-	-	-	-	-	-	-	-
BIGNABAM_00412	2.79e-19	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
BIGNABAM_00413	1.92e-42	-	-	-	S	-	-	-	protein encoded in hypervariable junctions of pilus gene clusters
BIGNABAM_00415	1.17e-45	-	-	-	-	-	-	-	-
BIGNABAM_00416	3e-271	tnpB	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
BIGNABAM_00417	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
BIGNABAM_00419	2.06e-56	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_00420	0.0	-	-	-	E	-	-	-	Amino acid permease
BIGNABAM_00421	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
BIGNABAM_00422	3.2e-18	-	-	-	-	-	-	-	-
BIGNABAM_00423	2.76e-83	-	-	-	-	-	-	-	-
BIGNABAM_00424	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
BIGNABAM_00425	0.0	prtB	3.4.21.96	-	O	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
BIGNABAM_00426	6.27e-224	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
BIGNABAM_00427	1.69e-121	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
BIGNABAM_00428	1.41e-72	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
BIGNABAM_00429	1.73e-157	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
BIGNABAM_00430	4.21e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
BIGNABAM_00431	5.29e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
BIGNABAM_00432	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
BIGNABAM_00433	4.02e-238	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
BIGNABAM_00434	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
BIGNABAM_00435	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
BIGNABAM_00436	2.51e-281	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BIGNABAM_00437	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
BIGNABAM_00438	6.54e-251	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
BIGNABAM_00439	2.14e-48	-	-	-	-	-	-	-	-
BIGNABAM_00440	1.54e-222	-	-	-	K	ko:K03484	-	ko00000,ko03000	Periplasmic binding protein domain
BIGNABAM_00441	1.93e-303	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGNABAM_00442	1.7e-201	msmF	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_00443	8.75e-197	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_00444	1.72e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGNABAM_00445	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
BIGNABAM_00446	0.0	gtfA	2.4.1.7	GH13	G	ko:K00690	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose glucosyltransferase
BIGNABAM_00447	3.08e-147	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
BIGNABAM_00448	7.52e-136	dltr	-	-	K	-	-	-	response regulator
BIGNABAM_00449	3.72e-300	sptS	-	-	T	-	-	-	Histidine kinase
BIGNABAM_00450	3.34e-267	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
BIGNABAM_00451	1.59e-90	-	-	-	O	-	-	-	OsmC-like protein
BIGNABAM_00452	1.93e-122	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
BIGNABAM_00453	1.24e-116	-	-	-	-	-	-	-	-
BIGNABAM_00454	0.0	-	-	-	-	-	-	-	-
BIGNABAM_00455	1.87e-107	-	-	-	S	-	-	-	Fic/DOC family
BIGNABAM_00456	0.0	potE	-	-	E	-	-	-	Amino Acid
BIGNABAM_00457	3.32e-283	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BIGNABAM_00458	2.12e-311	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
BIGNABAM_00459	1.2e-59	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
BIGNABAM_00460	8.67e-151	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
BIGNABAM_00461	1.6e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
BIGNABAM_00462	4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
BIGNABAM_00463	3.3e-159	-	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
BIGNABAM_00464	1.87e-58	-	-	-	-	-	-	-	-
BIGNABAM_00465	0.0	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
BIGNABAM_00466	3.8e-48	eriC	-	-	P	ko:K03281	-	ko00000	chloride
BIGNABAM_00468	2.73e-154	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BIGNABAM_00469	1.56e-164	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
BIGNABAM_00470	2.64e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
BIGNABAM_00471	1.68e-121	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BIGNABAM_00472	2.22e-231	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
BIGNABAM_00473	2.04e-313	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
BIGNABAM_00474	4.22e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
BIGNABAM_00475	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
BIGNABAM_00476	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
BIGNABAM_00477	2.89e-191	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
BIGNABAM_00478	8.74e-62	-	-	-	-	-	-	-	-
BIGNABAM_00479	2.88e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
BIGNABAM_00480	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
BIGNABAM_00481	5.44e-56	-	-	-	S	-	-	-	Alpha beta hydrolase
BIGNABAM_00482	4.93e-49	-	-	-	-	-	-	-	-
BIGNABAM_00483	4.33e-69	-	-	-	-	-	-	-	-
BIGNABAM_00484	2.69e-188	supH	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BIGNABAM_00485	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGNABAM_00486	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGNABAM_00487	1.82e-86	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
BIGNABAM_00488	3.02e-228	lipA	-	-	I	-	-	-	Carboxylesterase family
BIGNABAM_00490	7.03e-271	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
BIGNABAM_00491	1.48e-202	cinI	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
BIGNABAM_00492	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
BIGNABAM_00493	2.07e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
BIGNABAM_00495	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
BIGNABAM_00496	1.5e-193	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BIGNABAM_00497	6.82e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
BIGNABAM_00498	3.94e-64	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
BIGNABAM_00499	4.31e-257	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
BIGNABAM_00500	2.11e-133	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BIGNABAM_00501	1.61e-92	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
BIGNABAM_00502	3.38e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BIGNABAM_00503	2.06e-198	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BIGNABAM_00504	4.86e-249	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BIGNABAM_00505	1.53e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
BIGNABAM_00506	5.51e-206	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
BIGNABAM_00507	7.22e-197	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
BIGNABAM_00508	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
BIGNABAM_00509	8.94e-100	-	-	-	S	-	-	-	ASCH
BIGNABAM_00510	5.97e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
BIGNABAM_00511	2.37e-46	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
BIGNABAM_00512	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BIGNABAM_00513	1.27e-219	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BIGNABAM_00514	3.18e-310	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BIGNABAM_00515	1.98e-180	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
BIGNABAM_00516	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
BIGNABAM_00517	3.75e-212	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
BIGNABAM_00518	1.51e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
BIGNABAM_00519	3.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
BIGNABAM_00520	6.84e-43	-	-	-	-	-	-	-	-
BIGNABAM_00521	4.02e-151	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BIGNABAM_00522	2.53e-146	-	-	-	L	-	-	-	Helix-turn-helix domain of transposase family ISL3
BIGNABAM_00523	1.33e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
BIGNABAM_00524	8.29e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
BIGNABAM_00525	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
BIGNABAM_00526	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BIGNABAM_00527	3.69e-233	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
BIGNABAM_00528	2.98e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BIGNABAM_00531	1.39e-197	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00532	9.2e-317	malF	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_00533	2.73e-282	-	-	-	G	ko:K15770	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGNABAM_00534	4.23e-268	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGNABAM_00535	9.37e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
BIGNABAM_00536	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
BIGNABAM_00537	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
BIGNABAM_00538	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
BIGNABAM_00539	1.5e-101	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
BIGNABAM_00540	1.58e-282	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BIGNABAM_00541	6.36e-230	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
BIGNABAM_00542	7.48e-188	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
BIGNABAM_00543	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BIGNABAM_00544	2.61e-195	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
BIGNABAM_00545	7.13e-123	-	-	-	-	-	-	-	-
BIGNABAM_00546	1.78e-29	-	-	-	-	-	-	-	-
BIGNABAM_00547	6.42e-199	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00548	6.95e-62	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
BIGNABAM_00549	2.45e-58	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
BIGNABAM_00550	1.3e-90	-	-	-	L	-	-	-	RelB antitoxin
BIGNABAM_00552	4.51e-170	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
BIGNABAM_00553	2.11e-108	-	-	-	M	-	-	-	NlpC/P60 family
BIGNABAM_00556	1.16e-48	-	-	-	-	-	-	-	-
BIGNABAM_00557	9.05e-206	-	-	-	EG	-	-	-	EamA-like transporter family
BIGNABAM_00558	4.04e-212	-	-	-	EG	-	-	-	EamA-like transporter family
BIGNABAM_00559	1.28e-152	yicL	-	-	EG	-	-	-	EamA-like transporter family
BIGNABAM_00560	2.28e-138	-	-	-	-	-	-	-	-
BIGNABAM_00561	1.5e-141	-	-	-	-	-	-	-	-
BIGNABAM_00562	1.84e-238	-	-	-	S	-	-	-	DUF218 domain
BIGNABAM_00563	0.0	yheS_2	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
BIGNABAM_00564	3.49e-113	-	-	-	-	-	-	-	-
BIGNABAM_00565	1.09e-74	-	-	-	-	-	-	-	-
BIGNABAM_00566	6.51e-40	-	-	-	S	-	-	-	Protein conserved in bacteria
BIGNABAM_00567	5.2e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BIGNABAM_00568	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BIGNABAM_00569	1.16e-239	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BIGNABAM_00572	1.07e-262	-	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
BIGNABAM_00573	6.23e-243	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
BIGNABAM_00574	2.75e-292	-	-	-	E	-	-	-	amino acid
BIGNABAM_00575	8.09e-180	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
BIGNABAM_00576	2.26e-220	-	-	-	S	-	-	-	PFAM Archaeal ATPase
BIGNABAM_00577	8.72e-313	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
BIGNABAM_00578	6.49e-310	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
BIGNABAM_00579	4.18e-148	sipS3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
BIGNABAM_00580	7.1e-148	-	-	-	V	-	-	-	ABC transporter transmembrane region
BIGNABAM_00581	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	AAA domain (Cdc48 subfamily)
BIGNABAM_00582	4.74e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
BIGNABAM_00583	3.77e-305	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_00584	2.39e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00585	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
BIGNABAM_00586	1.96e-49	-	-	-	-	-	-	-	-
BIGNABAM_00587	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
BIGNABAM_00588	1.34e-183	lysA2	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
BIGNABAM_00589	1.24e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
BIGNABAM_00590	3.75e-216	pbpX2	-	-	V	-	-	-	Beta-lactamase
BIGNABAM_00591	6.8e-316	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
BIGNABAM_00592	4.98e-48	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BIGNABAM_00593	2.53e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
BIGNABAM_00594	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
BIGNABAM_00595	9.18e-27	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
BIGNABAM_00596	6.47e-64	-	-	-	-	-	-	-	-
BIGNABAM_00597	3.27e-277	-	-	-	S	-	-	-	Membrane
BIGNABAM_00598	3.41e-107	ykuL	-	-	S	-	-	-	(CBS) domain
BIGNABAM_00599	0.0	cadA	-	-	P	-	-	-	P-type ATPase
BIGNABAM_00600	1.4e-263	napA	-	-	P	-	-	-	Sodium/hydrogen exchanger family
BIGNABAM_00601	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
BIGNABAM_00602	1.36e-89	-	-	-	S	-	-	-	Putative adhesin
BIGNABAM_00603	2.95e-204	mutR	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00604	9.39e-71	-	-	-	-	-	-	-	-
BIGNABAM_00605	3.62e-202	-	-	-	EGP	-	-	-	Major facilitator Superfamily
BIGNABAM_00606	2.86e-139	ywdE	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional regulator
BIGNABAM_00607	7.21e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
BIGNABAM_00608	6e-247	-	-	-	S	-	-	-	DUF218 domain
BIGNABAM_00609	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00610	0.0	ppc	4.1.1.31	-	H	ko:K01595	ko00620,ko00680,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BIGNABAM_00611	7.18e-131	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
BIGNABAM_00612	1.69e-256	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
BIGNABAM_00613	3.28e-257	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein PnrA-like
BIGNABAM_00614	0.0	mglA	3.6.3.17	-	S	ko:K02056,ko:K06400	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
BIGNABAM_00615	8.8e-262	mglC	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGNABAM_00616	3.63e-221	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGNABAM_00617	2.64e-206	-	-	-	S	-	-	-	Aldo/keto reductase family
BIGNABAM_00618	2.59e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
BIGNABAM_00619	5.04e-147	dak	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
BIGNABAM_00620	4.86e-165	dgk2	2.7.1.76	-	F	ko:K10353	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	deoxynucleoside kinase
BIGNABAM_00621	5.46e-93	-	-	-	-	-	-	-	-
BIGNABAM_00622	1.02e-169	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BIGNABAM_00623	6.82e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
BIGNABAM_00624	2.07e-119	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00625	3.5e-101	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
BIGNABAM_00626	1.43e-153	-	-	-	S	-	-	-	ABC-2 family transporter protein
BIGNABAM_00627	2.29e-165	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
BIGNABAM_00628	3.28e-295	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
BIGNABAM_00629	3.69e-54	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
BIGNABAM_00630	5.05e-11	-	-	-	-	-	-	-	-
BIGNABAM_00631	4.1e-60	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
BIGNABAM_00632	3.84e-52	-	-	-	S	ko:K07124	-	ko00000	Enoyl-(Acyl carrier protein) reductase
BIGNABAM_00633	3.71e-87	yneE	-	-	K	-	-	-	Transcriptional regulator
BIGNABAM_00634	1.11e-79	yneE	-	-	K	-	-	-	Transcriptional regulator
BIGNABAM_00635	1.56e-287	-	-	-	S	ko:K07133	-	ko00000	cog cog1373
BIGNABAM_00636	5.26e-188	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
BIGNABAM_00637	3.66e-292	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
BIGNABAM_00638	1.28e-38	-	-	-	-	-	-	-	-
BIGNABAM_00639	1.02e-74	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_00640	6.14e-106	-	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
BIGNABAM_00641	3.36e-100	copY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
BIGNABAM_00642	4.19e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
BIGNABAM_00643	4.44e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
BIGNABAM_00644	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
BIGNABAM_00645	1.1e-145	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
BIGNABAM_00646	3.14e-137	-	-	-	-	-	-	-	-
BIGNABAM_00647	1.28e-315	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
BIGNABAM_00648	6.46e-27	-	-	-	-	-	-	-	-
BIGNABAM_00649	8.24e-271	-	-	-	-	-	-	-	-
BIGNABAM_00650	6.36e-114	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_00651	8.29e-76	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00652	3.98e-41	-	-	-	E	-	-	-	Zn peptidase
BIGNABAM_00653	0.0	-	-	-	L	-	-	-	Transposase
BIGNABAM_00654	1.16e-128	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
BIGNABAM_00655	2.41e-148	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
BIGNABAM_00656	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
BIGNABAM_00657	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
BIGNABAM_00658	5.27e-97	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
BIGNABAM_00660	5.41e-89	-	-	-	C	-	-	-	lyase activity
BIGNABAM_00661	9.23e-225	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGNABAM_00662	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
BIGNABAM_00663	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BIGNABAM_00664	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
BIGNABAM_00665	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
BIGNABAM_00666	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BIGNABAM_00667	2.65e-189	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
BIGNABAM_00668	3.62e-79	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
BIGNABAM_00669	3.26e-23	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
BIGNABAM_00670	1.83e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BIGNABAM_00671	6.66e-244	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
BIGNABAM_00672	1.13e-48	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
BIGNABAM_00673	1.79e-268	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BIGNABAM_00674	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BIGNABAM_00675	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BIGNABAM_00676	1.93e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
BIGNABAM_00677	7.46e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
BIGNABAM_00678	1.89e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BIGNABAM_00679	1.98e-115	-	-	-	E	-	-	-	Zn peptidase
BIGNABAM_00680	8.87e-54	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_00681	1.31e-55	-	-	-	-	-	-	-	-
BIGNABAM_00682	1.39e-92	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
BIGNABAM_00683	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
BIGNABAM_00685	4.58e-226	-	-	-	C	-	-	-	Oxidoreductase
BIGNABAM_00686	8.18e-105	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
BIGNABAM_00687	9.37e-68	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BIGNABAM_00688	1.96e-69	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
BIGNABAM_00689	1.49e-94	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
BIGNABAM_00690	4.31e-190	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
BIGNABAM_00691	1.6e-48	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
BIGNABAM_00692	6.44e-106	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
BIGNABAM_00693	3.82e-44	-	-	-	M	-	-	-	Peptidase family M1 domain
BIGNABAM_00694	4.07e-77	-	-	-	M	-	-	-	Peptidase family M1 domain
BIGNABAM_00695	6.34e-193	-	-	-	-	-	-	-	-
BIGNABAM_00697	2.29e-315	-	-	-	M	-	-	-	Glycosyl transferase
BIGNABAM_00698	7.23e-263	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
BIGNABAM_00699	1.77e-207	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
BIGNABAM_00700	1.51e-112	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
BIGNABAM_00701	2.34e-38	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
BIGNABAM_00702	1.15e-104	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
BIGNABAM_00703	7.6e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
BIGNABAM_00704	2.25e-137	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
BIGNABAM_00705	4.73e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BIGNABAM_00706	9.4e-151	yjcA	-	-	S	ko:K19350	ko02010,map02010	ko00000,ko00001,ko01504,ko02000	ABC transporter
BIGNABAM_00707	4.04e-143	ybbB	-	-	S	-	-	-	Protein of unknown function (DUF1211)
BIGNABAM_00708	1.26e-97	ltrA	-	-	S	-	-	-	Bacterial low temperature requirement A protein (LtrA)
BIGNABAM_00709	6.47e-155	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
BIGNABAM_00710	5.69e-314	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
BIGNABAM_00711	0.0	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
BIGNABAM_00712	4.96e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BIGNABAM_00714	0.000802	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
BIGNABAM_00715	1.54e-128	rbtT	-	-	P	ko:K13021	-	ko00000,ko02000	Major Facilitator Superfamily
BIGNABAM_00716	5.71e-262	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
BIGNABAM_00717	3.24e-113	-	-	-	K	-	-	-	GNAT family
BIGNABAM_00718	1.46e-161	-	-	-	S	-	-	-	Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
BIGNABAM_00720	6.04e-49	-	-	-	-	-	-	-	-
BIGNABAM_00721	0.0	-	-	-	P	ko:K06148	-	ko00000,ko02000	ABC transporter
BIGNABAM_00722	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGNABAM_00723	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
BIGNABAM_00724	1.27e-231	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BIGNABAM_00725	5.55e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BIGNABAM_00726	0.0	aha1	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
BIGNABAM_00727	5.41e-225	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
BIGNABAM_00728	1.78e-204	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
BIGNABAM_00729	5.74e-243	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BIGNABAM_00730	2.34e-122	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00731	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
BIGNABAM_00732	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
BIGNABAM_00733	1.66e-217	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
BIGNABAM_00734	0.0	pepC4	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
BIGNABAM_00735	5.26e-171	-	-	-	H	-	-	-	Aldolase/RraA
BIGNABAM_00736	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
BIGNABAM_00737	3.45e-196	-	-	-	I	-	-	-	Alpha/beta hydrolase family
BIGNABAM_00738	6.29e-250	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
BIGNABAM_00739	1.6e-59	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
BIGNABAM_00740	2.54e-214	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
BIGNABAM_00741	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
BIGNABAM_00742	1.24e-93	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
BIGNABAM_00743	1.46e-31	-	-	-	-	-	-	-	-
BIGNABAM_00744	2.58e-189	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
BIGNABAM_00745	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00746	7.34e-123	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
BIGNABAM_00747	8.1e-87	-	-	-	S	-	-	-	Domain of unknown function DUF1828
BIGNABAM_00748	7.91e-14	-	-	-	-	-	-	-	-
BIGNABAM_00749	2.93e-67	-	-	-	-	-	-	-	-
BIGNABAM_00750	1.66e-183	citR	-	-	K	-	-	-	Putative sugar-binding domain
BIGNABAM_00751	6.02e-282	-	-	-	S	-	-	-	Putative threonine/serine exporter
BIGNABAM_00752	1.3e-115	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BIGNABAM_00753	1.38e-223	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
BIGNABAM_00754	9.32e-81	-	-	-	-	-	-	-	-
BIGNABAM_00755	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BIGNABAM_00756	1.8e-99	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
BIGNABAM_00757	4.28e-312	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
BIGNABAM_00758	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
BIGNABAM_00759	5.51e-284	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
BIGNABAM_00760	5.43e-276	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BIGNABAM_00761	9.85e-199	-	-	-	S	-	-	-	reductase
BIGNABAM_00762	3.84e-192	yxeH	-	-	S	-	-	-	hydrolase
BIGNABAM_00763	3.99e-231	gyaR	1.1.1.26, 1.1.1.399, 1.1.1.95	-	CH	ko:K00015,ko:K00058	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BIGNABAM_00764	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
BIGNABAM_00765	3.87e-141	yngC	-	-	S	-	-	-	SNARE associated Golgi protein
BIGNABAM_00766	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
BIGNABAM_00767	5.39e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BIGNABAM_00768	0.0	oatA	-	-	I	-	-	-	Acyltransferase
BIGNABAM_00769	5e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
BIGNABAM_00770	8.69e-186	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
BIGNABAM_00771	3.57e-47	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
BIGNABAM_00772	5.14e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
BIGNABAM_00773	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BIGNABAM_00774	1.25e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
BIGNABAM_00775	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
BIGNABAM_00776	5.46e-233	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
BIGNABAM_00777	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
BIGNABAM_00778	1.72e-213	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
BIGNABAM_00779	1.16e-213	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
BIGNABAM_00780	1.88e-80	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BIGNABAM_00781	8.61e-168	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BIGNABAM_00782	7.57e-135	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BIGNABAM_00783	1.89e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
BIGNABAM_00784	8.49e-146	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
BIGNABAM_00785	1.13e-41	-	-	-	M	-	-	-	Lysin motif
BIGNABAM_00786	1.96e-148	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
BIGNABAM_00787	1.15e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
BIGNABAM_00788	1.34e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
BIGNABAM_00789	8.21e-57	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
BIGNABAM_00790	7.11e-293	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
BIGNABAM_00791	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIGNABAM_00792	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
BIGNABAM_00793	1.01e-64	-	-	-	-	-	-	-	-
BIGNABAM_00794	3.66e-114	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_00795	1.36e-76	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_00796	1.5e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
BIGNABAM_00797	1.29e-64	-	-	-	S	-	-	-	MazG-like family
BIGNABAM_00798	9.27e-86	-	-	-	-	-	-	-	-
BIGNABAM_00799	3.08e-155	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
BIGNABAM_00800	0.0	-	-	-	-	-	-	-	-
BIGNABAM_00801	2.95e-123	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
BIGNABAM_00802	1.09e-177	-	-	-	S	-	-	-	Alpha/beta hydrolase family
BIGNABAM_00803	1.87e-87	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
BIGNABAM_00804	1.17e-55	yxaM	-	-	EGP	-	-	-	Major facilitator Superfamily
BIGNABAM_00805	2.84e-68	-	-	-	F	-	-	-	Phosphorylase superfamily
BIGNABAM_00806	1.11e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
BIGNABAM_00807	4.04e-110	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_00808	6.22e-43	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_00809	2.42e-70	codA	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
BIGNABAM_00810	9.2e-154	-	-	-	S	-	-	-	F420-0:Gamma-glutamyl ligase
BIGNABAM_00811	3.85e-105	-	-	-	S	-	-	-	AAA domain
BIGNABAM_00812	2.06e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
BIGNABAM_00813	1.2e-187	-	-	-	F	-	-	-	Phosphorylase superfamily
BIGNABAM_00814	2.16e-193	-	2.3.1.81	-	V	ko:K00662	-	ko00000,ko01000,ko01504	Aminoglycoside 3-N-acetyltransferase
BIGNABAM_00815	9.6e-106	-	-	-	E	-	-	-	amino acid
BIGNABAM_00816	1.27e-109	yagE	-	-	E	-	-	-	Amino acid permease
BIGNABAM_00817	2.75e-111	-	3.4.21.96	-	S	ko:K01361	-	ko00000,ko01000,ko01002,ko03110	SLAP domain
BIGNABAM_00818	8.13e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BIGNABAM_00819	1.47e-286	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
BIGNABAM_00820	1.8e-143	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
BIGNABAM_00821	8.63e-191	degV3	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
BIGNABAM_00822	9.85e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
BIGNABAM_00823	3.73e-218	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
BIGNABAM_00824	4.52e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BIGNABAM_00825	4.08e-168	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BIGNABAM_00826	5.24e-196	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
BIGNABAM_00827	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BIGNABAM_00828	1.42e-315	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BIGNABAM_00829	2.09e-180	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Phage integrase, N-terminal SAM-like domain
BIGNABAM_00830	4.67e-116	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BIGNABAM_00831	1.4e-313	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BIGNABAM_00832	1.21e-245	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGNABAM_00833	3.27e-229	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGNABAM_00834	2.27e-220	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_00835	3.06e-181	oppC5	-	-	P	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_00836	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00837	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00838	2.8e-160	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
BIGNABAM_00839	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
BIGNABAM_00840	3.65e-230	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BIGNABAM_00841	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BIGNABAM_00842	4.18e-25	-	-	-	-	-	-	-	-
BIGNABAM_00843	1.89e-172	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00844	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
BIGNABAM_00845	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
BIGNABAM_00846	2.75e-72	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
BIGNABAM_00847	5.7e-291	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BIGNABAM_00848	6.78e-60	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
BIGNABAM_00849	2.08e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BIGNABAM_00850	1.98e-174	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
BIGNABAM_00851	1.64e-74	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
BIGNABAM_00852	8.95e-273	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_00853	6.91e-156	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
BIGNABAM_00854	1.69e-185	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
BIGNABAM_00855	9.86e-146	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BIGNABAM_00856	4.16e-51	ynzC	-	-	S	-	-	-	UPF0291 protein
BIGNABAM_00857	1.3e-40	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
BIGNABAM_00858	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BIGNABAM_00859	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
BIGNABAM_00860	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
BIGNABAM_00861	5.69e-39	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
BIGNABAM_00862	1.41e-109	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
BIGNABAM_00863	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00864	4.24e-185	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_00865	4.32e-77	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_00866	6.44e-23	-	-	-	D	-	-	-	Domain of Unknown Function (DUF1542)
BIGNABAM_00867	1.58e-29	-	-	-	-	-	-	-	-
BIGNABAM_00868	4.52e-81	XK27_01125	-	-	L	ko:K07484	-	ko00000	PFAM IS66 Orf2 family protein
BIGNABAM_00869	1.47e-301	-	-	-	L	ko:K07484	-	ko00000	Transposase IS66 family
BIGNABAM_00870	3.67e-276	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
BIGNABAM_00871	0.0	-	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
BIGNABAM_00872	4.4e-172	-	-	-	-	-	-	-	-
BIGNABAM_00873	4.81e-76	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
BIGNABAM_00874	4.85e-97	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
BIGNABAM_00875	7.86e-287	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
BIGNABAM_00876	2.08e-145	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
BIGNABAM_00877	1.79e-245	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
BIGNABAM_00878	9.01e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
BIGNABAM_00879	4.33e-236	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BIGNABAM_00880	5.86e-168	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
BIGNABAM_00881	2.87e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
BIGNABAM_00882	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BIGNABAM_00883	2.88e-183	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
BIGNABAM_00884	2.59e-253	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
BIGNABAM_00885	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
BIGNABAM_00886	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BIGNABAM_00887	3.4e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
BIGNABAM_00888	1.02e-260	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
BIGNABAM_00889	1.08e-62	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
BIGNABAM_00890	1.61e-64	ylxQ	-	-	J	-	-	-	ribosomal protein
BIGNABAM_00891	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BIGNABAM_00892	2.88e-80	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BIGNABAM_00893	9.89e-200	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BIGNABAM_00894	2.65e-223	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
BIGNABAM_00895	2.56e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
BIGNABAM_00896	3.74e-109	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BIGNABAM_00897	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
BIGNABAM_00898	5.88e-278	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
BIGNABAM_00899	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
BIGNABAM_00900	5.5e-130	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
BIGNABAM_00901	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
BIGNABAM_00902	4.68e-121	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BIGNABAM_00903	1.12e-65	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00904	2.93e-75	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_00905	1.94e-135	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
BIGNABAM_00913	1.11e-253	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
BIGNABAM_00914	4.39e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
BIGNABAM_00915	0.000168	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
BIGNABAM_00916	6.6e-53	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
BIGNABAM_00917	6.04e-65	-	-	-	S	-	-	-	Metal binding domain of Ada
BIGNABAM_00918	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
BIGNABAM_00919	1.5e-177	lysR5	-	-	K	-	-	-	LysR substrate binding domain
BIGNABAM_00920	4.52e-302	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
BIGNABAM_00921	7.44e-51	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIGNABAM_00922	5.49e-47	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIGNABAM_00923	1.25e-140	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
BIGNABAM_00924	9.06e-125	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
BIGNABAM_00925	4.37e-287	-	-	-	S	-	-	-	Sterol carrier protein domain
BIGNABAM_00926	4.04e-29	-	-	-	-	-	-	-	-
BIGNABAM_00927	1.03e-141	-	-	-	K	-	-	-	LysR substrate binding domain
BIGNABAM_00928	6.82e-128	-	-	-	-	-	-	-	-
BIGNABAM_00929	2.92e-153	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
BIGNABAM_00930	1.31e-158	-	-	-	-	-	-	-	-
BIGNABAM_00931	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGNABAM_00932	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGNABAM_00933	1.84e-92	-	-	-	-	-	-	-	-
BIGNABAM_00934	8.71e-31	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
BIGNABAM_00935	1.32e-92	-	-	-	K	-	-	-	sequence-specific DNA binding
BIGNABAM_00936	2.96e-55	-	-	-	S	-	-	-	SnoaL-like domain
BIGNABAM_00937	0.0	-	-	-	L	-	-	-	PLD-like domain
BIGNABAM_00938	1.32e-130	yrgI	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Histidine phosphatase superfamily (branch 1)
BIGNABAM_00939	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
BIGNABAM_00940	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
BIGNABAM_00941	5.96e-283	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
BIGNABAM_00942	2.62e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
BIGNABAM_00943	7.77e-151	-	-	-	-	-	-	-	-
BIGNABAM_00944	5.11e-208	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BIGNABAM_00946	6.57e-141	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BIGNABAM_00947	1.71e-150	-	-	-	S	-	-	-	Peptidase family M23
BIGNABAM_00948	1.05e-131	-	-	-	-	-	-	-	-
BIGNABAM_00949	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	E1-E2 ATPase
BIGNABAM_00950	5.51e-46	-	-	-	C	-	-	-	Heavy-metal-associated domain
BIGNABAM_00951	3.97e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
BIGNABAM_00952	2.61e-147	fnr	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
BIGNABAM_00954	2.18e-96	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BIGNABAM_00955	1.93e-116	ymdB	-	-	S	-	-	-	Macro domain protein
BIGNABAM_00956	1.87e-288	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
BIGNABAM_00957	9.28e-224	-	-	-	-	-	-	-	-
BIGNABAM_00958	2.2e-79	lysM	-	-	M	-	-	-	LysM domain
BIGNABAM_00959	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
BIGNABAM_00960	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
BIGNABAM_00961	1.15e-34	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
BIGNABAM_00962	6.23e-102	-	-	-	K	-	-	-	LytTr DNA-binding domain
BIGNABAM_00963	5.74e-167	-	-	-	S	-	-	-	membrane
BIGNABAM_00964	1.83e-309	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
BIGNABAM_00965	4.34e-22	-	-	-	-	-	-	-	-
BIGNABAM_00966	5.56e-255	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
BIGNABAM_00967	2.25e-202	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
BIGNABAM_00968	6.91e-151	-	-	-	-	-	-	-	-
BIGNABAM_00969	6.15e-185	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
BIGNABAM_00970	3.42e-181	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
BIGNABAM_00971	1.66e-144	-	-	-	G	-	-	-	phosphoglycerate mutase
BIGNABAM_00972	7.8e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGNABAM_00973	6.08e-233	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
BIGNABAM_00974	2.12e-132	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00975	1.75e-126	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
BIGNABAM_00976	4.3e-197	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
BIGNABAM_00977	1.6e-197	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
BIGNABAM_00978	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BIGNABAM_00979	6.73e-51	-	-	-	-	-	-	-	-
BIGNABAM_00980	7.51e-145	-	-	-	K	-	-	-	WHG domain
BIGNABAM_00981	3.41e-125	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
BIGNABAM_00982	2.58e-126	azr	1.5.1.36	-	S	ko:K22394	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
BIGNABAM_00983	1.57e-192	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
BIGNABAM_00984	5.24e-230	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
BIGNABAM_00986	4.24e-75	cvpA	-	-	S	-	-	-	Colicin V production protein
BIGNABAM_00987	3.14e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
BIGNABAM_00988	7.14e-192	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
BIGNABAM_00989	1.67e-176	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
BIGNABAM_00990	6.08e-197	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
BIGNABAM_00991	1.1e-59	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
BIGNABAM_00992	6.88e-257	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
BIGNABAM_00993	3.93e-176	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
BIGNABAM_00994	0.0	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_00995	0.0	ndvA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
BIGNABAM_00996	8.32e-157	vanR	-	-	K	-	-	-	response regulator
BIGNABAM_00997	1.32e-270	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
BIGNABAM_00998	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BIGNABAM_00999	9.1e-185	racD	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
BIGNABAM_01000	2.07e-71	-	-	-	S	-	-	-	Enterocin A Immunity
BIGNABAM_01001	1.95e-45	-	-	-	-	-	-	-	-
BIGNABAM_01002	1.07e-35	-	-	-	-	-	-	-	-
BIGNABAM_01003	4.48e-34	-	-	-	-	-	-	-	-
BIGNABAM_01004	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
BIGNABAM_01005	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
BIGNABAM_01006	8.52e-21	-	-	-	-	-	-	-	-
BIGNABAM_01007	8.18e-89	-	-	-	-	-	-	-	-
BIGNABAM_01009	4.43e-272	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
BIGNABAM_01010	1.16e-11	-	-	-	-	-	-	-	-
BIGNABAM_01011	1.07e-265	-	-	-	S	-	-	-	CAAX protease self-immunity
BIGNABAM_01013	4.62e-258	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
BIGNABAM_01014	3.83e-184	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
BIGNABAM_01015	5.59e-41	-	-	-	-	-	-	-	-
BIGNABAM_01016	1.65e-83	-	-	-	-	-	-	-	-
BIGNABAM_01017	7.44e-40	-	-	-	-	-	-	-	-
BIGNABAM_01018	2.2e-89	-	-	-	M	-	-	-	Glycosyl transferase family 2
BIGNABAM_01022	6.57e-253	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
BIGNABAM_01023	2.34e-31	-	-	-	-	-	-	-	-
BIGNABAM_01024	1.73e-109	-	-	-	-	-	-	-	-
BIGNABAM_01025	2.58e-41	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
BIGNABAM_01026	7.23e-32	-	-	-	-	-	-	-	-
BIGNABAM_01027	1.19e-88	-	-	-	-	-	-	-	-
BIGNABAM_01028	1.01e-12	-	-	-	-	-	-	-	-
BIGNABAM_01029	2.18e-41	-	-	-	-	-	-	-	-
BIGNABAM_01030	5.12e-211	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_01031	9.07e-279	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
BIGNABAM_01032	3.14e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
BIGNABAM_01033	2.18e-215	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
BIGNABAM_01034	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
BIGNABAM_01035	4.47e-56	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
BIGNABAM_01036	1.25e-188	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
BIGNABAM_01037	1.63e-152	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
BIGNABAM_01038	2.63e-171	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
BIGNABAM_01039	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
BIGNABAM_01040	2.6e-31	-	-	-	K	-	-	-	Transcriptional regulator
BIGNABAM_01043	8.89e-95	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
BIGNABAM_01044	1.24e-100	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
BIGNABAM_01048	8.05e-87	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
BIGNABAM_01049	6.85e-165	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease
BIGNABAM_01051	4.47e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
BIGNABAM_01052	1.27e-271	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
BIGNABAM_01053	3.84e-09	-	-	-	S	-	-	-	Enterocin A Immunity
BIGNABAM_01054	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
BIGNABAM_01055	1.39e-277	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
BIGNABAM_01056	2.8e-160	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
BIGNABAM_01057	9.4e-128	-	-	-	-	-	-	-	-
BIGNABAM_01058	4.4e-132	rimL	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
BIGNABAM_01059	4.03e-82	-	-	-	-	-	-	-	-
BIGNABAM_01060	0.0	-	-	-	S	-	-	-	ABC transporter
BIGNABAM_01061	3.12e-50	-	-	-	S	-	-	-	Putative threonine/serine exporter
BIGNABAM_01062	7.22e-107	-	-	-	S	-	-	-	Putative threonine/serine exporter
BIGNABAM_01063	7.36e-109	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
BIGNABAM_01064	3.18e-143	-	-	-	S	-	-	-	Peptidase_C39 like family
BIGNABAM_01065	4.73e-101	-	-	-	-	-	-	-	-
BIGNABAM_01066	9.74e-227	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BIGNABAM_01067	1.17e-101	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
BIGNABAM_01068	8.77e-144	-	-	-	-	-	-	-	-
BIGNABAM_01069	0.0	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
BIGNABAM_01070	4.7e-58	-	-	-	-	-	-	-	-
BIGNABAM_01071	5.02e-123	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase homologues.
BIGNABAM_01072	2.67e-124	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
BIGNABAM_01073	1.28e-174	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
BIGNABAM_01074	1.73e-167	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC/P60 family
BIGNABAM_01075	3.01e-54	-	-	-	-	-	-	-	-
BIGNABAM_01077	1.53e-224	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
BIGNABAM_01078	8.93e-290	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BIGNABAM_01080	9.52e-56	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
BIGNABAM_01081	2.09e-63	yoeB	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
BIGNABAM_01082	3.61e-244	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
BIGNABAM_01083	4.06e-189	epsB	-	-	M	-	-	-	biosynthesis protein
BIGNABAM_01084	3.54e-163	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
BIGNABAM_01085	3.16e-184	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
BIGNABAM_01086	1.23e-144	epsE2	-	-	M	-	-	-	Bacterial sugar transferase
BIGNABAM_01087	4.72e-199	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
BIGNABAM_01088	6.33e-79	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family 2
BIGNABAM_01089	1.45e-60	rgpB	-	GT2	M	ko:K12997	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
BIGNABAM_01090	2.38e-58	-	-	GT2	S	ko:K12990	ko02024,ko02025,map02024,map02025	ko00000,ko00001,ko01000,ko01003,ko01005	Glycosyl transferase family group 2
BIGNABAM_01091	2.03e-14	-	-	-	M	-	-	-	Glycosyl transferase, group 2 family
BIGNABAM_01092	4.3e-65	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
BIGNABAM_01094	1.92e-263	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
BIGNABAM_01095	0.0	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
BIGNABAM_01097	2.88e-75	-	-	-	S	-	-	-	Acyltransferase family
BIGNABAM_01098	9.53e-70	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
BIGNABAM_01099	1.9e-74	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
BIGNABAM_01101	2.93e-154	-	-	-	L	-	-	-	Transposase
BIGNABAM_01102	7.2e-278	-	-	-	L	-	-	-	Transposase
BIGNABAM_01103	7.87e-221	-	-	-	D	-	-	-	nuclear chromosome segregation
BIGNABAM_01104	2.66e-197	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
BIGNABAM_01105	1.61e-70	-	-	-	-	-	-	-	-
BIGNABAM_01106	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
BIGNABAM_01107	6.39e-102	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BIGNABAM_01108	9.3e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
BIGNABAM_01109	3.39e-254	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
BIGNABAM_01110	0.0	carB1	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
BIGNABAM_01111	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
BIGNABAM_01112	2.06e-88	-	-	-	-	-	-	-	-
BIGNABAM_01113	8.12e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
BIGNABAM_01114	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BIGNABAM_01115	6.14e-259	xerS	-	-	L	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family
BIGNABAM_01116	3.03e-90	-	-	-	-	-	-	-	-
BIGNABAM_01117	4.36e-142	XK27_00160	-	-	S	-	-	-	Domain of unknown function (DUF5052)
BIGNABAM_01118	4.08e-270	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
BIGNABAM_01119	7.55e-53	-	-	-	S	-	-	-	Transglycosylase associated protein
BIGNABAM_01120	6.59e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
BIGNABAM_01121	5.03e-76	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_01122	2.45e-146	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BIGNABAM_01123	5.18e-222	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
BIGNABAM_01124	9.08e-234	-	-	-	K	-	-	-	Transcriptional regulator
BIGNABAM_01125	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BIGNABAM_01126	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
BIGNABAM_01127	9.39e-141	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BIGNABAM_01128	9.25e-300	snf	-	-	KL	-	-	-	domain protein
BIGNABAM_01129	0.0	snf	-	-	KL	-	-	-	domain protein
BIGNABAM_01131	1.49e-50	-	-	-	-	-	-	-	-
BIGNABAM_01132	1.24e-08	-	-	-	-	-	-	-	-
BIGNABAM_01133	4.83e-136	pncA	-	-	Q	-	-	-	Isochorismatase family
BIGNABAM_01134	7.5e-160	-	-	-	-	-	-	-	-
BIGNABAM_01137	4.13e-83	-	-	-	-	-	-	-	-
BIGNABAM_01138	7.18e-47	-	-	-	-	-	-	-	-
BIGNABAM_01139	9.91e-150	-	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
BIGNABAM_01140	9.67e-104	-	-	-	-	-	-	-	-
BIGNABAM_01141	6.74e-309	cpdA	-	-	S	-	-	-	Calcineurin-like phosphoesterase
BIGNABAM_01142	5.87e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
BIGNABAM_01143	1.85e-90	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
BIGNABAM_01144	1.18e-139	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
BIGNABAM_01145	8.47e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
BIGNABAM_01146	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
BIGNABAM_01147	1.92e-148	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BIGNABAM_01148	6.91e-149	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
BIGNABAM_01149	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
BIGNABAM_01150	4.08e-117	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
BIGNABAM_01151	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
BIGNABAM_01152	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
BIGNABAM_01153	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
BIGNABAM_01154	2.59e-174	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	GHMP kinases N terminal domain
BIGNABAM_01155	1.01e-228	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
BIGNABAM_01156	6.67e-261	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
BIGNABAM_01157	4.17e-237	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
BIGNABAM_01158	1.28e-150	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
BIGNABAM_01159	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
BIGNABAM_01160	1.72e-212	-	-	-	-	-	-	-	-
BIGNABAM_01161	2.41e-185	-	-	-	-	-	-	-	-
BIGNABAM_01162	3.65e-133	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
BIGNABAM_01163	4.24e-37	-	-	-	-	-	-	-	-
BIGNABAM_01164	1.98e-52	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
BIGNABAM_01165	4.74e-151	-	-	-	-	-	-	-	-
BIGNABAM_01166	2.56e-134	-	-	-	-	-	-	-	-
BIGNABAM_01167	1.17e-155	-	-	-	-	-	-	-	-
BIGNABAM_01168	7.68e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
BIGNABAM_01169	1.25e-80	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
BIGNABAM_01170	2.45e-308	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
BIGNABAM_01171	6.95e-197	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BIGNABAM_01172	1.19e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
BIGNABAM_01173	1.54e-105	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
BIGNABAM_01174	1.51e-166	-	-	-	S	-	-	-	Peptidase family M23
BIGNABAM_01175	9e-255	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
BIGNABAM_01176	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
BIGNABAM_01177	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
BIGNABAM_01178	9.03e-229	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
BIGNABAM_01179	1.05e-175	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
BIGNABAM_01180	1.6e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BIGNABAM_01181	3.58e-129	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BIGNABAM_01182	1.74e-224	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
BIGNABAM_01183	3.75e-93	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
BIGNABAM_01184	4.83e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
BIGNABAM_01185	6.94e-199	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
BIGNABAM_01186	9.23e-214	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
BIGNABAM_01187	2.88e-221	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BIGNABAM_01188	9.47e-158	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
BIGNABAM_01189	6.1e-170	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
BIGNABAM_01190	2.78e-253	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
BIGNABAM_01191	1.85e-142	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
BIGNABAM_01192	0.0	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
BIGNABAM_01193	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
BIGNABAM_01194	1.6e-58	-	-	-	-	-	-	-	-
BIGNABAM_01196	5.34e-134	-	-	-	-	-	-	-	-
BIGNABAM_01198	1.14e-175	-	-	-	-	-	-	-	-
BIGNABAM_01199	1.09e-272	pmrA	-	-	EGP	ko:K08161	-	ko00000,ko02000	MFS_1 like family
BIGNABAM_01200	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
BIGNABAM_01201	1.51e-117	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BIGNABAM_01202	9.57e-303	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
BIGNABAM_01203	2.68e-48	-	-	-	-	-	-	-	-
BIGNABAM_01204	9.72e-190	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
BIGNABAM_01205	1.03e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_01206	0.0	-	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
BIGNABAM_01207	1.52e-119	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGNABAM_01208	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
BIGNABAM_01213	1.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_01214	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BIGNABAM_01215	1.18e-255	flp	-	-	V	-	-	-	Beta-lactamase
BIGNABAM_01216	2.79e-309	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
BIGNABAM_01217	4.03e-186	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
BIGNABAM_01218	1.46e-75	-	-	-	-	-	-	-	-
BIGNABAM_01219	2.61e-148	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
BIGNABAM_01220	9.65e-220	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
BIGNABAM_01221	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BIGNABAM_01222	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
BIGNABAM_01223	5.42e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BIGNABAM_01224	6.25e-268	camS	-	-	S	-	-	-	sex pheromone
BIGNABAM_01225	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BIGNABAM_01226	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
BIGNABAM_01227	3.29e-127	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
BIGNABAM_01229	1.11e-110	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
BIGNABAM_01230	1.91e-173	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
BIGNABAM_01231	0.0	epsU	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
BIGNABAM_01232	1.3e-286	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
BIGNABAM_01233	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
BIGNABAM_01234	6.65e-196	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
BIGNABAM_01235	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BIGNABAM_01236	1.77e-262	-	-	-	M	-	-	-	Glycosyl transferases group 1
BIGNABAM_01237	5.23e-172	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
BIGNABAM_01238	3.68e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
BIGNABAM_01239	1.87e-159	gntR1	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
BIGNABAM_01240	7.57e-233	-	-	-	-	-	-	-	-
BIGNABAM_01241	0.0	oppA2	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
BIGNABAM_01242	3.7e-281	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGNABAM_01243	6.02e-44	-	-	-	K	-	-	-	Transcriptional
BIGNABAM_01245	2.45e-27	-	-	-	-	-	-	-	-
BIGNABAM_01248	4.29e-64	-	-	-	-	-	-	-	-
BIGNABAM_01249	0.0	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
BIGNABAM_01253	7.01e-82	-	-	-	-	-	-	-	-
BIGNABAM_01256	7.62e-306	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
BIGNABAM_01257	1.48e-14	-	-	-	-	-	-	-	-
BIGNABAM_01258	6.39e-32	-	-	-	S	-	-	-	transposase or invertase
BIGNABAM_01259	3.35e-309	slpX	-	-	S	-	-	-	SLAP domain
BIGNABAM_01260	5.82e-186	-	-	-	K	-	-	-	SIS domain
BIGNABAM_01261	6.34e-156	rpiA1	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
BIGNABAM_01262	2.16e-239	XK27_10475	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
BIGNABAM_01263	8.3e-98	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
BIGNABAM_01264	2.33e-162	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
BIGNABAM_01265	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
BIGNABAM_01267	1.8e-146	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
BIGNABAM_01268	2.79e-146	-	-	-	G	-	-	-	Antibiotic biosynthesis monooxygenase
BIGNABAM_01269	1.64e-129	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
BIGNABAM_01270	8.92e-136	-	-	-	G	-	-	-	Phosphoglycerate mutase family
BIGNABAM_01271	8.07e-211	-	-	-	D	-	-	-	nuclear chromosome segregation
BIGNABAM_01272	1.44e-130	-	-	-	M	-	-	-	LysM domain protein
BIGNABAM_01273	4.06e-37	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_01274	9.19e-71	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_01275	1.25e-17	-	-	-	-	-	-	-	-
BIGNABAM_01276	1.95e-220	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
BIGNABAM_01277	2.54e-42	-	-	-	-	-	-	-	-
BIGNABAM_01279	1.09e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
BIGNABAM_01280	4.39e-145	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
BIGNABAM_01281	2.84e-80	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
BIGNABAM_01283	9.44e-184	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
BIGNABAM_01284	1.59e-78	-	-	-	-	-	-	-	-
BIGNABAM_01285	0.0	-	-	-	L	ko:K03724	-	ko00000,ko01000,ko03400	DEAD DEAH box helicase
BIGNABAM_01286	0.0	-	-	-	P	-	-	-	P-loop Domain of unknown function (DUF2791)
BIGNABAM_01287	0.0	-	-	-	S	-	-	-	TerB-C domain
BIGNABAM_01288	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
BIGNABAM_01289	3.03e-76	apfA	3.6.1.61	-	F	ko:K18445	ko00230,map00230	ko00000,ko00001,ko01000	Nudix hydrolase
BIGNABAM_01290	1.66e-42	-	-	-	-	-	-	-	-
BIGNABAM_01291	1.23e-170	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
BIGNABAM_01292	1.98e-279	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
BIGNABAM_01293	5.75e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_01294	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
BIGNABAM_01295	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
BIGNABAM_01296	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
BIGNABAM_01297	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
BIGNABAM_01298	1.44e-311	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
BIGNABAM_01299	1.56e-115	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
BIGNABAM_01300	2.94e-203	-	-	-	K	-	-	-	Transcriptional regulator
BIGNABAM_01301	2.76e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF956)
BIGNABAM_01302	3.51e-222	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
BIGNABAM_01303	3.23e-179	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
BIGNABAM_01304	3.31e-237	manL	2.7.1.191	-	G	ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
BIGNABAM_01306	8.05e-278	yqjV	-	-	EGP	-	-	-	Major Facilitator Superfamily
BIGNABAM_01307	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
BIGNABAM_01308	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
BIGNABAM_01309	2.36e-94	-	-	-	-	-	-	-	-
BIGNABAM_01310	3.75e-48	-	-	-	S	-	-	-	PFAM Archaeal ATPase
BIGNABAM_01312	2.77e-25	-	-	-	-	-	-	-	-
BIGNABAM_01313	1.21e-40	-	-	-	-	-	-	-	-
BIGNABAM_01314	2.56e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
BIGNABAM_01315	2.68e-134	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_01316	2.47e-250	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
BIGNABAM_01317	4.33e-95	-	-	-	-	-	-	-	-
BIGNABAM_01319	9.28e-113	-	-	-	K	-	-	-	DNA-templated transcription, initiation
BIGNABAM_01321	1.46e-69	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
BIGNABAM_01322	2.46e-29	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
BIGNABAM_01323	1.32e-178	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_01327	3.24e-119	-	-	-	-	-	-	-	-
BIGNABAM_01328	1.41e-284	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
BIGNABAM_01329	5.97e-265	-	3.2.1.96, 3.5.1.28	GH73	M	ko:K01227,ko:K01447,ko:K13714,ko:K13731	ko00511,ko05100,map00511,map05100	ko00000,ko00001,ko01000	N-acetylmuramoyl-L-alanine amidase
BIGNABAM_01330	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
BIGNABAM_01331	1.57e-150	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BIGNABAM_01332	6.61e-230	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
BIGNABAM_01333	8.33e-186	-	-	-	-	-	-	-	-
BIGNABAM_01334	6.81e-172	-	-	-	-	-	-	-	-
BIGNABAM_01335	4.51e-171	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BIGNABAM_01336	1.22e-126	-	-	-	G	-	-	-	Aldose 1-epimerase
BIGNABAM_01337	2.06e-258	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
BIGNABAM_01338	1.03e-145	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
BIGNABAM_01339	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
BIGNABAM_01340	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
BIGNABAM_01341	1.27e-309	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BIGNABAM_01342	3.98e-72	-	-	-	-	-	-	-	-
BIGNABAM_01344	0.0	pepC2	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
BIGNABAM_01345	2.62e-159	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
BIGNABAM_01346	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
BIGNABAM_01347	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
BIGNABAM_01348	4.39e-267	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
BIGNABAM_01349	1.34e-191	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BIGNABAM_01350	6.71e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BIGNABAM_01351	1.74e-252	oppD	-	-	P	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGNABAM_01352	6.54e-222	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
BIGNABAM_01353	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
BIGNABAM_01354	3.4e-93	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
BIGNABAM_01355	5.69e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
BIGNABAM_01356	1.43e-144	-	-	-	-	-	-	-	-
BIGNABAM_01358	7.04e-145	-	-	-	E	-	-	-	Belongs to the SOS response-associated peptidase family
BIGNABAM_01359	6.74e-244	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
BIGNABAM_01360	4.29e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	MafB19-like deaminase
BIGNABAM_01361	3.22e-135	-	-	-	S	ko:K06872	-	ko00000	TPM domain
BIGNABAM_01362	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
BIGNABAM_01363	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BIGNABAM_01364	7.48e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
BIGNABAM_01365	5.17e-129	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
BIGNABAM_01366	2.33e-205	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
BIGNABAM_01367	1.72e-53	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
BIGNABAM_01368	1.44e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
BIGNABAM_01369	7.68e-309	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BIGNABAM_01370	5.52e-113	-	-	-	-	-	-	-	-
BIGNABAM_01371	0.0	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_01372	1.09e-225	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BIGNABAM_01373	3.1e-216	-	-	-	GK	-	-	-	ROK family
BIGNABAM_01374	2.08e-57	-	-	-	-	-	-	-	-
BIGNABAM_01375	0.0	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
BIGNABAM_01376	7.59e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF1934)
BIGNABAM_01377	4.63e-92	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
BIGNABAM_01378	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
BIGNABAM_01379	1.89e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BIGNABAM_01380	4.9e-95	-	-	-	K	-	-	-	acetyltransferase
BIGNABAM_01381	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BIGNABAM_01382	4.35e-198	msmR	-	-	K	-	-	-	AraC-like ligand binding domain
BIGNABAM_01383	3.96e-292	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
BIGNABAM_01384	5.57e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
BIGNABAM_01385	4.41e-11	-	-	-	K	-	-	-	Helix-turn-helix
BIGNABAM_01386	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
BIGNABAM_01388	2.66e-125	-	-	-	D	-	-	-	nuclear chromosome segregation
BIGNABAM_01391	3.24e-06	-	-	-	L	-	-	-	Transposase
BIGNABAM_01392	1.38e-107	-	-	-	J	-	-	-	FR47-like protein
BIGNABAM_01393	3.37e-50	-	-	-	S	-	-	-	Cytochrome B5
BIGNABAM_01394	2.27e-214	arbZ	-	-	I	-	-	-	Phosphate acyltransferases
BIGNABAM_01395	3.7e-233	-	-	-	M	-	-	-	Glycosyl transferase family 8
BIGNABAM_01396	4.7e-237	-	-	-	M	-	-	-	Glycosyl transferase family 8
BIGNABAM_01397	7.53e-203	arbx	-	-	M	-	-	-	Glycosyl transferase family 8
BIGNABAM_01398	3.58e-193	-	-	-	I	-	-	-	Acyl-transferase
BIGNABAM_01400	6.33e-46	-	-	-	-	-	-	-	-
BIGNABAM_01402	3.98e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
BIGNABAM_01403	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
BIGNABAM_01404	0.0	yycH	-	-	S	-	-	-	YycH protein
BIGNABAM_01405	7.44e-192	yycI	-	-	S	-	-	-	YycH protein
BIGNABAM_01406	2.4e-188	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
BIGNABAM_01407	2.87e-227	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
BIGNABAM_01408	8.64e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BIGNABAM_01409	1.68e-44	-	-	-	G	-	-	-	Peptidase_C39 like family
BIGNABAM_01410	1.31e-208	-	-	-	M	-	-	-	NlpC/P60 family
BIGNABAM_01411	2.34e-115	-	-	-	G	-	-	-	Peptidase_C39 like family
BIGNABAM_01412	1.05e-221	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
BIGNABAM_01413	2.28e-112	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
BIGNABAM_01414	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_01415	1.05e-222	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
BIGNABAM_01416	2.98e-136	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_01417	1.63e-112	-	-	-	-	-	-	-	-
BIGNABAM_01418	3e-05	-	-	-	-	-	-	-	-
BIGNABAM_01419	4.19e-100	-	-	-	M	-	-	-	LysM domain
BIGNABAM_01420	1.97e-105	-	-	-	-	-	-	-	-
BIGNABAM_01421	1.41e-208	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
BIGNABAM_01422	2.03e-125	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
BIGNABAM_01423	1.52e-245	ysdE	-	-	P	-	-	-	Citrate transporter
BIGNABAM_01424	1.36e-91	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
BIGNABAM_01425	0.0	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Membrane domain of glycerophosphoryl diester phosphodiesterase
BIGNABAM_01426	9.69e-25	-	-	-	-	-	-	-	-
BIGNABAM_01427	6.1e-166	-	-	-	-	-	-	-	-
BIGNABAM_01428	2.77e-10	-	-	-	-	-	-	-	-
BIGNABAM_01429	4.29e-205	-	-	-	M	-	-	-	Glycosyl transferase
BIGNABAM_01430	2.11e-53	-	-	-	M	-	-	-	Glycosyl transferase
BIGNABAM_01431	3.67e-225	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
BIGNABAM_01432	1.11e-154	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
BIGNABAM_01433	1.1e-200	-	-	-	L	-	-	-	HNH nucleases
BIGNABAM_01434	3.92e-185	yhaH	-	-	S	-	-	-	Protein of unknown function (DUF805)
BIGNABAM_01435	3.38e-172	glnQ	-	-	E	ko:K17076	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_01436	0.0	XK27_05795	-	-	P	ko:K17073,ko:K17074	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
BIGNABAM_01437	1.41e-155	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
BIGNABAM_01438	3.78e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
BIGNABAM_01439	5.93e-167	terC	-	-	P	-	-	-	Integral membrane protein TerC family
BIGNABAM_01440	2.16e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
BIGNABAM_01441	4.22e-115	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
BIGNABAM_01442	5.2e-34	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
BIGNABAM_01443	5.61e-113	-	-	-	-	-	-	-	-
BIGNABAM_01444	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BIGNABAM_01445	2.14e-233	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
BIGNABAM_01446	5.07e-190	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BIGNABAM_01447	9.18e-187	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
BIGNABAM_01448	3.29e-193	epsV	-	-	S	-	-	-	glycosyl transferase family 2
BIGNABAM_01449	3.19e-165	-	-	-	S	-	-	-	Alpha/beta hydrolase family
BIGNABAM_01450	2.91e-189	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_01452	1.9e-79	-	-	-	-	-	-	-	-
BIGNABAM_01454	1.07e-17	-	-	-	S	-	-	-	YcaO cyclodehydratase, ATP-ad Mg2+-binding
BIGNABAM_01455	3.02e-276	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
BIGNABAM_01456	1.29e-179	noxC	1.5.1.39	-	C	ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	coenzyme F420-1:gamma-L-glutamate ligase activity
BIGNABAM_01457	8.73e-234	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BIGNABAM_01458	8.37e-161	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGNABAM_01459	1.11e-177	-	-	-	-	-	-	-	-
BIGNABAM_01460	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
BIGNABAM_01461	1.23e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_01462	4.45e-292	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
BIGNABAM_01463	7.15e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
BIGNABAM_01464	2.07e-160	-	-	-	-	-	-	-	-
BIGNABAM_01465	1.69e-258	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
BIGNABAM_01466	3.17e-166	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
BIGNABAM_01467	7.57e-207	-	-	-	I	-	-	-	alpha/beta hydrolase fold
BIGNABAM_01468	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
BIGNABAM_01469	1.53e-277	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BIGNABAM_01470	0.0	-	-	-	S	ko:K06921	-	ko00000	Archaea bacterial proteins of unknown function
BIGNABAM_01472	4.83e-117	ntd	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside
BIGNABAM_01473	1.94e-115	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
BIGNABAM_01474	1.45e-190	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
BIGNABAM_01475	2.66e-110	usp5	-	-	T	-	-	-	universal stress protein
BIGNABAM_01476	4.65e-206	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
BIGNABAM_01477	5.59e-174	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BIGNABAM_01478	5.6e-162	phnB	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_01479	1.83e-190	-	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_01480	1.38e-138	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
BIGNABAM_01481	3e-108	-	-	-	-	-	-	-	-
BIGNABAM_01482	0.0	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
BIGNABAM_01483	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
BIGNABAM_01484	0.0	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
BIGNABAM_01485	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
BIGNABAM_01486	1.35e-180	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BIGNABAM_01487	2.18e-132	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
BIGNABAM_01488	4.42e-292	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
BIGNABAM_01491	1.3e-104	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
BIGNABAM_01492	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
BIGNABAM_01493	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIGNABAM_01494	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIGNABAM_01495	7.71e-157	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
BIGNABAM_01496	1.47e-91	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BIGNABAM_01497	1.39e-106	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
BIGNABAM_01498	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BIGNABAM_01499	6.34e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
BIGNABAM_01500	6.64e-146	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BIGNABAM_01501	4.68e-138	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
BIGNABAM_01502	1.14e-63	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
BIGNABAM_01503	4.01e-198	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BIGNABAM_01504	1.14e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BIGNABAM_01505	9.07e-73	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BIGNABAM_01506	8.7e-157	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BIGNABAM_01507	1.66e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BIGNABAM_01508	1.45e-34	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
BIGNABAM_01509	1.56e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BIGNABAM_01510	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BIGNABAM_01511	3.03e-44	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BIGNABAM_01512	1.23e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BIGNABAM_01513	1e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BIGNABAM_01514	7.94e-90	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BIGNABAM_01515	7.18e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BIGNABAM_01516	4.84e-73	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BIGNABAM_01517	3.73e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BIGNABAM_01518	2.22e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
BIGNABAM_01519	4.95e-93	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
BIGNABAM_01520	3.59e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
BIGNABAM_01521	3.7e-155	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
BIGNABAM_01522	3.13e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BIGNABAM_01523	1.89e-21	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
BIGNABAM_01524	2.07e-73	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BIGNABAM_01525	3.82e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BIGNABAM_01526	3.62e-218	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIGNABAM_01527	2.23e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
BIGNABAM_01528	4.16e-198	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BIGNABAM_01529	6.7e-203	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BIGNABAM_01530	1.13e-177	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BIGNABAM_01531	3.57e-193	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
BIGNABAM_01532	3.22e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BIGNABAM_01533	1.18e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
BIGNABAM_01534	1.57e-201	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
BIGNABAM_01535	6.48e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_01536	1.17e-137	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
BIGNABAM_01537	5.45e-153	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
BIGNABAM_01538	4.97e-170	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
BIGNABAM_01539	3.84e-161	-	-	-	G	-	-	-	Belongs to the phosphoglycerate mutase family
BIGNABAM_01540	5.08e-207	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
BIGNABAM_01541	2.42e-33	-	-	-	-	-	-	-	-
BIGNABAM_01542	2.31e-162	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BIGNABAM_01543	1.99e-235	-	-	-	S	-	-	-	AAA domain
BIGNABAM_01544	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	COG0474 Cation transport ATPase
BIGNABAM_01545	8.27e-52	-	-	-	-	-	-	-	-
BIGNABAM_01546	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
BIGNABAM_01547	7.79e-70	-	-	-	-	-	-	-	-
BIGNABAM_01548	5.22e-131	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
BIGNABAM_01549	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BIGNABAM_01550	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BIGNABAM_01551	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
BIGNABAM_01552	8.55e-99	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BIGNABAM_01553	2.69e-178	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIGNABAM_01554	3.81e-123	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
BIGNABAM_01555	1.19e-45	-	-	-	-	-	-	-	-
BIGNABAM_01556	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
BIGNABAM_01557	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BIGNABAM_01558	3.73e-33	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
BIGNABAM_01559	3.01e-131	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
BIGNABAM_01560	2.69e-90	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BIGNABAM_01561	1.05e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
BIGNABAM_01562	5.48e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
BIGNABAM_01563	1.19e-212	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
BIGNABAM_01564	1.82e-198	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
BIGNABAM_01565	5.24e-187	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BIGNABAM_01566	4.66e-179	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
BIGNABAM_01567	2.89e-151	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
BIGNABAM_01568	5.61e-118	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_01570	3.72e-111	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BIGNABAM_01571	1.61e-72	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
BIGNABAM_01572	6.56e-189	-	2.1.1.172	-	J	ko:K00564,ko:K10716	-	ko00000,ko01000,ko02000,ko03009	Ion channel
BIGNABAM_01573	5.31e-149	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
BIGNABAM_01574	6.15e-36	-	-	-	-	-	-	-	-
BIGNABAM_01575	1.08e-117	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
BIGNABAM_01576	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BIGNABAM_01577	1.19e-46	-	-	-	M	-	-	-	lipopolysaccharide 3-alpha-galactosyltransferase activity
BIGNABAM_01578	1.55e-68	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BIGNABAM_01579	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BIGNABAM_01580	1.18e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
BIGNABAM_01581	1.15e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BIGNABAM_01582	1.58e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
BIGNABAM_01583	1.45e-199	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
BIGNABAM_01584	1.4e-80	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
BIGNABAM_01585	1.84e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BIGNABAM_01586	3.85e-179	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
BIGNABAM_01587	1.83e-112	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
BIGNABAM_01588	1.62e-171	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
BIGNABAM_01589	3.93e-125	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
BIGNABAM_01590	4.42e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BIGNABAM_01591	6.39e-230	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
BIGNABAM_01592	2.21e-162	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
BIGNABAM_01593	4.47e-312	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
BIGNABAM_01594	8.78e-157	XK27_10290	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
BIGNABAM_01595	1.35e-71	ytpP	-	-	CO	-	-	-	Thioredoxin
BIGNABAM_01597	2.16e-163	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
BIGNABAM_01598	1.34e-280	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
BIGNABAM_01599	3.67e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_01600	4.63e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
BIGNABAM_01601	1.2e-41	-	-	-	-	-	-	-	-
BIGNABAM_01602	2.2e-196	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
BIGNABAM_01603	5.74e-96	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
BIGNABAM_01604	0.0	-	-	-	-	-	-	-	-
BIGNABAM_01605	3.33e-241	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
BIGNABAM_01606	0.0	yhaN	-	-	L	-	-	-	AAA domain
BIGNABAM_01607	4.13e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
BIGNABAM_01608	8.43e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
BIGNABAM_01609	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
BIGNABAM_01610	8.5e-208	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
BIGNABAM_01611	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
BIGNABAM_01612	7.87e-144	-	-	-	G	-	-	-	Phosphoglycerate mutase family
BIGNABAM_01613	6.65e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
BIGNABAM_01614	2.35e-162	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
BIGNABAM_01615	4.09e-249	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
BIGNABAM_01616	1.26e-233	-	-	-	S	-	-	-	PFAM Archaeal ATPase
BIGNABAM_01617	2.2e-308	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_01618	1.22e-173	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
BIGNABAM_01620	4.1e-120	-	-	-	-	-	-	-	-
BIGNABAM_01622	1.77e-143	-	-	-	-	-	-	-	-
BIGNABAM_01623	3.23e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
BIGNABAM_01624	1.91e-116	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
BIGNABAM_01625	4.23e-21	-	-	-	-	-	-	-	-
BIGNABAM_01626	1.88e-106	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
BIGNABAM_01627	1.05e-106	-	-	-	L	-	-	-	NUDIX domain
BIGNABAM_01628	4.24e-217	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
BIGNABAM_01629	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
BIGNABAM_01630	2.9e-131	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
BIGNABAM_01631	1.83e-196	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BIGNABAM_01632	9.64e-307	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
BIGNABAM_01634	1.25e-63	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
BIGNABAM_01635	1.39e-167	-	-	-	F	-	-	-	NUDIX domain
BIGNABAM_01636	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BIGNABAM_01637	6.13e-138	pncA	-	-	Q	-	-	-	Isochorismatase family
BIGNABAM_01638	6.75e-60	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
BIGNABAM_01639	7.44e-59	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
BIGNABAM_01640	6.41e-105	-	-	-	S	-	-	-	Cupin domain
BIGNABAM_01642	1.1e-98	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
BIGNABAM_01643	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
BIGNABAM_01644	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
BIGNABAM_01645	9.81e-157	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
BIGNABAM_01646	1.66e-216	-	-	-	K	-	-	-	LysR substrate binding domain
BIGNABAM_01647	1.66e-117	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
BIGNABAM_01648	1.49e-294	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
BIGNABAM_01649	1.77e-207	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
BIGNABAM_01650	7.96e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
BIGNABAM_01651	3.54e-165	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
BIGNABAM_01652	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BIGNABAM_01653	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
BIGNABAM_01654	6.19e-239	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
BIGNABAM_01655	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
BIGNABAM_01656	1.76e-237	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
BIGNABAM_01657	5.19e-270	-	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
BIGNABAM_01658	1.14e-152	-	-	-	S	-	-	-	Putative esterase
BIGNABAM_01659	1.96e-153	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BIGNABAM_01660	1.92e-102	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
BIGNABAM_01661	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
BIGNABAM_01662	8.87e-288	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BIGNABAM_01665	4.05e-211	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
BIGNABAM_01668	1.57e-95	-	-	-	L	-	-	-	Transposase DDE domain
BIGNABAM_01669	0.0	XK27_00340	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BIGNABAM_01670	4.76e-137	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
BIGNABAM_01671	7.37e-60	-	-	-	S	-	-	-	polysaccharide biosynthetic process
BIGNABAM_01673	2.37e-136	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
BIGNABAM_01674	1.44e-116	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
BIGNABAM_01675	3.32e-13	-	-	-	-	-	-	-	-
BIGNABAM_01676	1.36e-110	-	-	-	-	-	-	-	-
BIGNABAM_01677	1.64e-55	-	-	-	-	-	-	-	-
BIGNABAM_01678	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase C-terminal domain
BIGNABAM_01679	1.43e-176	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
BIGNABAM_01680	4.71e-239	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
BIGNABAM_01681	6.6e-14	-	-	-	-	-	-	-	-
BIGNABAM_01682	6.28e-87	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
BIGNABAM_01683	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
BIGNABAM_01684	8.07e-164	-	-	-	-	-	-	-	-
BIGNABAM_01685	1.87e-308	-	-	-	S	-	-	-	response to antibiotic
BIGNABAM_01686	2.16e-162	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
BIGNABAM_01687	1.51e-150	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
BIGNABAM_01688	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
BIGNABAM_01689	1.81e-140	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
BIGNABAM_01690	8.38e-137	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
BIGNABAM_01691	1.43e-183	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_01692	2.34e-97	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_01693	1.13e-126	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
BIGNABAM_01694	2.03e-220	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
BIGNABAM_01695	5.16e-135	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BIGNABAM_01696	1.59e-131	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
BIGNABAM_01697	6.29e-82	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
BIGNABAM_01698	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
BIGNABAM_01699	2.43e-100	yybA	-	-	K	-	-	-	Transcriptional regulator
BIGNABAM_01700	1.15e-125	XK27_03150	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
BIGNABAM_01701	7.47e-134	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
BIGNABAM_01702	7.04e-115	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
BIGNABAM_01703	1.87e-316	-	-	-	T	-	-	-	GHKL domain
BIGNABAM_01704	2.9e-167	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
BIGNABAM_01705	2.7e-230	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
BIGNABAM_01706	0.0	-	-	-	V	-	-	-	ABC transporter transmembrane region
BIGNABAM_01707	2.46e-170	-	-	-	S	-	-	-	PAS domain
BIGNABAM_01709	2.82e-182	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
BIGNABAM_01710	1.3e-94	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
BIGNABAM_01711	6.39e-150	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
BIGNABAM_01712	8.83e-204	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BIGNABAM_01713	9.05e-231	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	EXOIII
BIGNABAM_01714	7.24e-204	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
BIGNABAM_01715	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
BIGNABAM_01716	6.14e-258	malK	-	-	P	ko:K10112,ko:K17240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
BIGNABAM_01717	1.64e-202	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	ABC-type sugar transport systems, permease components
BIGNABAM_01718	5.62e-187	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
BIGNABAM_01719	0.0	-	-	-	S	-	-	-	Zn-dependent metallo-hydrolase RNA specificity domain
BIGNABAM_01720	2.47e-309	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGNABAM_01721	1.4e-207	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
BIGNABAM_01722	6.6e-206	-	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
BIGNABAM_01723	3.76e-128	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
BIGNABAM_01724	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
BIGNABAM_01725	4.2e-221	-	-	-	-	-	-	-	-
BIGNABAM_01726	1.77e-93	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
BIGNABAM_01727	6.35e-291	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
BIGNABAM_01728	1.36e-260	pbpX	-	-	V	-	-	-	Beta-lactamase
BIGNABAM_01729	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
BIGNABAM_01730	0.0	-	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	amino acid
BIGNABAM_01731	2.08e-203	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
BIGNABAM_01733	1.44e-07	-	-	-	S	-	-	-	YSIRK type signal peptide
BIGNABAM_01734	9.62e-247	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BIGNABAM_01735	4.58e-181	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
BIGNABAM_01737	0.000118	-	-	-	-	-	-	-	-
BIGNABAM_01738	1.45e-31	-	-	-	-	-	-	-	-
BIGNABAM_01739	3.85e-193	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	haloacid dehalogenase-like hydrolase
BIGNABAM_01740	0.0	fusA1	-	-	J	-	-	-	elongation factor G
BIGNABAM_01741	6.43e-203	yvgN	-	-	C	-	-	-	Aldo keto reductase
BIGNABAM_01742	4.53e-205	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
BIGNABAM_01743	1.98e-172	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
BIGNABAM_01744	1.99e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
BIGNABAM_01745	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ABC-type multidrug transport system, ATPase and permease components
BIGNABAM_01746	2.88e-224	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
BIGNABAM_01747	3.9e-167	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
BIGNABAM_01748	2.48e-175	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
BIGNABAM_01749	1.59e-315	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
BIGNABAM_01750	2.55e-26	-	-	-	-	-	-	-	-
BIGNABAM_01751	1.67e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
BIGNABAM_01752	7.28e-225	ydbI	-	-	K	-	-	-	AI-2E family transporter
BIGNABAM_01753	0.0	oppA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
BIGNABAM_01754	1.3e-179	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
BIGNABAM_01755	0.0	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BIGNABAM_01756	1.57e-16	-	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BIGNABAM_01757	2.32e-20	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
BIGNABAM_01758	6.52e-104	-	-	-	S	-	-	-	Cob(I)alamin adenosyltransferase
BIGNABAM_01759	1.57e-189	-	-	-	S	-	-	-	Putative ABC-transporter type IV
BIGNABAM_01761	6.37e-39	-	-	-	-	-	-	-	-
BIGNABAM_01763	5.81e-155	-	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC family
BIGNABAM_01764	8.37e-298	-	-	-	I	-	-	-	Protein of unknown function (DUF2974)
BIGNABAM_01765	7.89e-32	-	-	-	S	-	-	-	Transglycosylase associated protein
BIGNABAM_01766	3.81e-18	-	-	-	S	-	-	-	CsbD-like
BIGNABAM_01767	1.73e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
BIGNABAM_01768	7.35e-221	degV1	-	-	S	-	-	-	DegV family
BIGNABAM_01769	2.36e-218	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, phosphonate, periplasmic substrate-binding protein
BIGNABAM_01770	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
BIGNABAM_01771	3.87e-97	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
BIGNABAM_01772	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
BIGNABAM_01773	6.67e-259	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_01774	1.07e-218	-	-	-	S	-	-	-	Bacteriocin helveticin-J
BIGNABAM_01775	9.4e-232	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
BIGNABAM_01776	4.62e-95	-	-	-	C	-	-	-	Aldo keto reductase
BIGNABAM_01777	5.61e-124	-	-	-	M	-	-	-	LysM domain protein
BIGNABAM_01778	5.49e-197	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
BIGNABAM_01779	9.28e-89	crcB1	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BIGNABAM_01780	1.25e-85	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BIGNABAM_01781	4.91e-17	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
BIGNABAM_01782	3.73e-146	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
BIGNABAM_01783	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
BIGNABAM_01784	9.58e-122	-	-	-	C	-	-	-	Pyridoxamine 5'-phosphate oxidase
BIGNABAM_01785	0.0	-	-	-	E	-	-	-	Amino acid permease
BIGNABAM_01786	0.0	speA	4.1.1.17, 4.1.1.18, 4.1.1.19	-	E	ko:K01581,ko:K01582,ko:K01585	ko00310,ko00330,ko00480,ko00960,ko01100,ko01110,ko01130,map00310,map00330,map00480,map00960,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Orn/Lys/Arg decarboxylase, C-terminal domain
BIGNABAM_01787	1.81e-313	ynbB	-	-	P	-	-	-	aluminum resistance
BIGNABAM_01788	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
BIGNABAM_01789	8.83e-107	-	-	-	C	-	-	-	Flavodoxin
BIGNABAM_01790	5.11e-134	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
BIGNABAM_01791	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC, A subunit
BIGNABAM_01792	2.25e-241	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
BIGNABAM_01793	1.15e-145	-	-	-	I	-	-	-	Acid phosphatase homologues
BIGNABAM_01794	3.21e-104	yvbK	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
BIGNABAM_01795	1.36e-150	maa3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
BIGNABAM_01796	7.55e-258	pbpX1	-	-	V	-	-	-	Beta-lactamase
BIGNABAM_01797	9.3e-129	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
BIGNABAM_01798	7.89e-124	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
BIGNABAM_01799	1.13e-291	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
BIGNABAM_01800	2.34e-107	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
BIGNABAM_01801	0.0	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
BIGNABAM_01802	3.95e-242	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
BIGNABAM_01803	4.58e-85	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
BIGNABAM_01804	0.0	treB	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
BIGNABAM_01805	5.32e-128	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
BIGNABAM_01806	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
BIGNABAM_01808	5.52e-302	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
BIGNABAM_01809	4.09e-80	-	-	-	S	ko:K07006	-	ko00000	Pyridoxamine 5'-phosphate oxidase
BIGNABAM_01810	2.94e-302	XK27_01810	-	-	S	-	-	-	Calcineurin-like phosphoesterase
BIGNABAM_01812	0.0	-	-	-	S	-	-	-	SLAP domain
BIGNABAM_01813	0.0	-	-	-	L	-	-	-	Type III restriction enzyme, res subunit
BIGNABAM_01815	1.54e-119	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
BIGNABAM_01816	4.93e-13	-	-	-	-	-	-	-	-
BIGNABAM_01819	8.87e-106	-	-	-	S	-	-	-	HIRAN
BIGNABAM_01820	7.25e-43	-	-	-	-	-	-	-	-
BIGNABAM_01821	1.18e-229	-	-	-	-	-	-	-	-
BIGNABAM_01822	2.88e-136	-	-	-	S	-	-	-	AAA domain
BIGNABAM_01823	6.62e-102	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
BIGNABAM_01824	5.55e-80	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphatidylserine decarboxylase family
BIGNABAM_01825	0.0	-	-	-	J	-	-	-	Elongation factor G, domain IV
BIGNABAM_01826	2.25e-37	-	-	-	-	-	-	-	-
BIGNABAM_01827	4.33e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
BIGNABAM_01828	6.9e-150	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
BIGNABAM_01829	2.15e-137	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
BIGNABAM_01830	1.1e-184	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
BIGNABAM_01831	6.48e-136	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
BIGNABAM_01832	0.0	sasH	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K07004,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
BIGNABAM_01833	9.89e-74	-	-	-	-	-	-	-	-
BIGNABAM_01834	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
BIGNABAM_01835	1.5e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
BIGNABAM_01836	4.59e-272	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
BIGNABAM_01837	3.09e-71	-	-	-	-	-	-	-	-
BIGNABAM_01838	2.96e-23	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
BIGNABAM_01839	1.74e-186	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
BIGNABAM_01840	4.9e-145	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BIGNABAM_01841	1.01e-186	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
BIGNABAM_01842	5.62e-95	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
BIGNABAM_01843	2.34e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
BIGNABAM_01844	2.19e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
BIGNABAM_01845	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
BIGNABAM_01846	1.18e-66	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
BIGNABAM_01847	9.37e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BIGNABAM_01848	5.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
BIGNABAM_01849	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BIGNABAM_01850	5.36e-305	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
BIGNABAM_01851	5.46e-232	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
BIGNABAM_01852	1.05e-275	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BIGNABAM_01853	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BIGNABAM_01854	7.58e-69	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
BIGNABAM_01855	4.87e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
BIGNABAM_01856	3.89e-132	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
BIGNABAM_01857	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BIGNABAM_01858	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BIGNABAM_01859	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
BIGNABAM_01860	1.06e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BIGNABAM_01861	3.25e-101	-	-	-	-	-	-	-	-
BIGNABAM_01862	2.14e-231	-	-	-	M	-	-	-	CHAP domain
BIGNABAM_01863	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
BIGNABAM_01864	7.93e-298	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
BIGNABAM_01865	6.92e-215	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
BIGNABAM_01866	1.23e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
BIGNABAM_01867	1.28e-69	-	-	-	-	ko:K19157	-	ko00000,ko01000,ko02048	-
BIGNABAM_01868	5.81e-286	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
BIGNABAM_01869	3.71e-264	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
BIGNABAM_01870	2.08e-208	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BIGNABAM_01871	2.86e-151	rfbC	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
BIGNABAM_01872	9.36e-229	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
BIGNABAM_01873	2.23e-27	-	-	-	-	-	-	-	-
BIGNABAM_01875	2.08e-54	-	-	-	K	-	-	-	transcriptional antiterminator
BIGNABAM_01876	5.03e-214	pts30BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
BIGNABAM_01877	2.68e-73	-	-	-	I	ko:K01066	-	ko00000,ko01000	Hydrolase, alpha beta domain protein
BIGNABAM_01879	4.26e-163	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
BIGNABAM_01880	3.65e-47	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
BIGNABAM_01881	4.98e-161	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_01882	6.59e-37	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
BIGNABAM_01883	6.71e-306	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGNABAM_01884	6.79e-139	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
BIGNABAM_01885	3.79e-100	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
BIGNABAM_01887	4.15e-207	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
BIGNABAM_01888	5.24e-85	-	-	-	-	-	-	-	-
BIGNABAM_01889	5.79e-14	-	-	-	-	-	-	-	-
BIGNABAM_01890	6.7e-107	-	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA domain
BIGNABAM_01891	7.85e-277	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
BIGNABAM_01892	2.43e-220	ptcC1	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
BIGNABAM_01893	7.21e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF3232)
BIGNABAM_01894	1.22e-181	-	-	-	-	-	-	-	-
BIGNABAM_01896	1.38e-15	fhaB	-	-	M	ko:K15125,ko:K18491	ko04550,ko05133,map04550,map05133	ko00000,ko00001,ko00536,ko03000	translation initiation factor activity
BIGNABAM_01897	8.7e-87	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
BIGNABAM_01898	2.68e-295	-	-	-	M	-	-	-	Rib/alpha-like repeat
BIGNABAM_01899	1.82e-05	-	-	-	-	-	-	-	-
BIGNABAM_01901	4.85e-75	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
BIGNABAM_01902	1.24e-31	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
BIGNABAM_01903	1.6e-79	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
BIGNABAM_01904	7.97e-252	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
BIGNABAM_01905	1.08e-123	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BIGNABAM_01906	3.74e-125	-	-	-	-	-	-	-	-
BIGNABAM_01907	2.22e-20	-	-	-	P	-	-	-	Voltage gated chloride channel
BIGNABAM_01908	1.59e-149	-	-	-	L	-	-	-	Resolvase, N-terminal
BIGNABAM_01909	0.0	-	-	-	L	ko:K07496	-	ko00000	Putative transposase DNA-binding domain
BIGNABAM_01910	3.91e-184	-	-	-	P	-	-	-	Voltage gated chloride channel
BIGNABAM_01911	2.54e-237	-	-	-	C	-	-	-	FMN-dependent dehydrogenase
BIGNABAM_01912	1.05e-69	-	-	-	-	-	-	-	-
BIGNABAM_01913	1.17e-56	-	-	-	-	-	-	-	-
BIGNABAM_01914	5.66e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BIGNABAM_01915	0.0	-	-	-	E	-	-	-	amino acid
BIGNABAM_01916	4.71e-200	yhaX	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
BIGNABAM_01917	0.0	dexB	3.2.1.70	-	G	ko:K01215	-	ko00000,ko01000	Alpha amylase, catalytic domain protein
BIGNABAM_01918	1.07e-52	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
BIGNABAM_01919	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
BIGNABAM_01920	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
BIGNABAM_01921	7.73e-79	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
BIGNABAM_01922	1.62e-276	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BIGNABAM_01923	5.03e-166	-	-	-	S	-	-	-	(CBS) domain
BIGNABAM_01924	2.93e-234	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
BIGNABAM_01941	3.04e-140	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGNABAM_01942	1.79e-18	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
BIGNABAM_01943	1.19e-125	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	VirC1 protein
BIGNABAM_01945	3.28e-126	-	-	-	-	-	-	-	-
BIGNABAM_01947	2.68e-96	-	-	-	KLT	-	-	-	serine threonine protein kinase
BIGNABAM_01948	8.6e-296	-	-	-	V	ko:K06147,ko:K06148	-	ko00000,ko02000	ABC transporter transmembrane region
BIGNABAM_01949	8.62e-121	-	-	-	-	-	-	-	-
BIGNABAM_01961	1.72e-286	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase 4-like domain
BIGNABAM_01962	9.03e-257	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
BIGNABAM_01963	8.57e-227	mprF	-	-	S	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BIGNABAM_01964	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
BIGNABAM_01965	1.3e-40	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
BIGNABAM_01966	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
BIGNABAM_01967	1.58e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
BIGNABAM_01968	3.03e-273	-	-	-	M	-	-	-	Peptidase family M1 domain
BIGNABAM_01969	2.55e-113	-	-	-	S	-	-	-	Alpha beta hydrolase
BIGNABAM_01970	1.46e-240	-	-	-	S	-	-	-	Bacteriocin helveticin-J
BIGNABAM_01971	1.33e-67	-	-	-	L	ko:K07473	-	ko00000,ko02048	RelB antitoxin
BIGNABAM_01972	2.95e-187	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
BIGNABAM_01973	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIGNABAM_01974	6.69e-200	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
BIGNABAM_01975	2.16e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BIGNABAM_01976	1.29e-106	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BIGNABAM_01977	0.0	dnaB2	-	-	L	ko:K03346	-	ko00000,ko03032	Replication initiation and membrane attachment
BIGNABAM_01978	4.39e-214	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
BIGNABAM_01979	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BIGNABAM_01980	2.68e-110	-	-	-	-	-	-	-	-
BIGNABAM_01981	1.19e-254	-	-	-	S	-	-	-	Domain of unknown function (DUF389)
BIGNABAM_01982	1.57e-190	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BIGNABAM_01983	3.71e-281	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
BIGNABAM_01984	1.11e-32	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BIGNABAM_01985	1.57e-68	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BIGNABAM_01986	2.43e-12	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BIGNABAM_01987	4.17e-142	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BIGNABAM_01988	5.57e-135	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
BIGNABAM_01989	1.6e-279	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BIGNABAM_01990	1.48e-166	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
BIGNABAM_01991	1.62e-71	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
BIGNABAM_01992	7.67e-115	nanK	-	-	GK	-	-	-	ROK family
BIGNABAM_01993	9.27e-155	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
BIGNABAM_01994	5.54e-85	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
BIGNABAM_01995	3.05e-173	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
BIGNABAM_01996	3.55e-56	-	-	-	L	-	-	-	Helix-turn-helix domain
BIGNABAM_01997	1.83e-57	-	-	-	L	-	-	-	Helix-turn-helix domain
BIGNABAM_01998	4.81e-293	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
BIGNABAM_01999	1.89e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
BIGNABAM_02000	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BIGNABAM_02001	7.32e-46	yabO	-	-	J	-	-	-	S4 domain protein
BIGNABAM_02002	7.52e-78	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
BIGNABAM_02003	3.95e-82	-	-	-	J	ko:K07571	-	ko00000	S1 RNA binding domain
BIGNABAM_02004	7.89e-307	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
BIGNABAM_02005	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BIGNABAM_02006	1.37e-214	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BIGNABAM_02007	1.67e-249	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BIGNABAM_02008	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
BIGNABAM_02012	5.1e-85	-	-	-	S	-	-	-	2-Nitropropane dioxygenase
BIGNABAM_02013	1.48e-148	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
BIGNABAM_02014	1.3e-300	-	-	-	I	-	-	-	Acyl-CoA dehydrogenase, C-terminal domain
BIGNABAM_02015	4.74e-286	frc	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
BIGNABAM_02016	4.07e-236	-	1.3.8.1, 1.3.8.6	-	I	ko:K00248,ko:K00252,ko:K18244	ko00071,ko00280,ko00310,ko00362,ko00380,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00071,map00280,map00310,map00362,map00380,map00650,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acyl-CoA dehydrogenase, C-terminal domain
BIGNABAM_02017	5.44e-67	-	-	-	C	-	-	-	Electron transfer flavoprotein domain
BIGNABAM_02018	8.1e-107	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein FAD-binding domain
BIGNABAM_02019	2.54e-206	-	6.2.1.3, 6.2.1.48	-	H	ko:K00666,ko:K01897,ko:K02182	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
BIGNABAM_02020	2e-40	-	-	-	I	-	-	-	Thioesterase superfamily
BIGNABAM_02021	4.88e-65	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
BIGNABAM_02022	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
BIGNABAM_02023	1.66e-117	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
BIGNABAM_02024	3.44e-203	plcR	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
BIGNABAM_02025	2.15e-195	-	-	-	I	-	-	-	alpha/beta hydrolase fold
BIGNABAM_02026	3.2e-143	-	-	-	S	-	-	-	SNARE associated Golgi protein
BIGNABAM_02027	1.23e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
BIGNABAM_02028	0.0	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BIGNABAM_02029	1.1e-135	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
BIGNABAM_02030	4.93e-12	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
BIGNABAM_02031	2.78e-291	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
BIGNABAM_02032	4.74e-34	-	-	-	S	-	-	-	PFAM Archaeal ATPase
BIGNABAM_02033	1.04e-139	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
BIGNABAM_02034	1.45e-204	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BIGNABAM_02035	1.28e-134	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
BIGNABAM_02036	5.02e-158	-	-	-	L	-	-	-	An automated process has identified a potential problem with this gene model
BIGNABAM_02037	1.26e-141	-	-	-	G	-	-	-	Major Facilitator Superfamily
BIGNABAM_02038	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
BIGNABAM_02039	8.63e-198	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
BIGNABAM_02040	7.25e-268	-	-	-	E	ko:K19956	ko00051,map00051	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
BIGNABAM_02041	1.98e-151	-	-	-	K	-	-	-	sugar-binding domain protein
BIGNABAM_02042	8.41e-169	srlD	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
BIGNABAM_02043	2.66e-59	-	2.7.1.206	-	G	ko:K02812	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
BIGNABAM_02044	2.99e-92	-	2.7.1.206	-	G	ko:K02813	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
BIGNABAM_02045	3.63e-150	-	-	-	U	ko:K02746,ko:K02795,ko:K02814	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
BIGNABAM_02046	1.25e-173	manZ	-	-	G	ko:K02796,ko:K02815	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
BIGNABAM_02047	2.12e-146	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
BIGNABAM_02048	1.43e-96	-	-	-	L	-	-	-	Transposase
BIGNABAM_02049	8.39e-186	-	-	-	L	-	-	-	Transposase
BIGNABAM_02050	6.47e-58	-	-	-	-	-	-	-	-
BIGNABAM_02051	2.34e-147	-	-	-	L	ko:K07497	-	ko00000	COG2963 Transposase and inactivated derivatives
BIGNABAM_02052	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
BIGNABAM_02053	9.09e-142	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BIGNABAM_02054	2.78e-86	-	-	-	K	-	-	-	LytTr DNA-binding domain
BIGNABAM_02055	1.56e-139	-	-	-	S	-	-	-	membrane
BIGNABAM_02057	5.71e-58	-	-	-	-	-	-	-	-
BIGNABAM_02058	1.89e-89	-	-	-	-	-	-	-	-
BIGNABAM_02059	1.53e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
BIGNABAM_02060	0.0	-	-	-	S	-	-	-	Uncharacterised protein family (UPF0236)
BIGNABAM_02061	8.07e-50	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives