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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HPMLHGED_00001	1.22e-316	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPMLHGED_00002	1.09e-90	-	-	-	S	-	-	-	ORF6N domain
HPMLHGED_00003	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00004	1.06e-256	-	-	-	-	-	-	-	-
HPMLHGED_00005	4.4e-288	-	-	-	M	-	-	-	Glycosyl transferase 4-like domain
HPMLHGED_00006	7.1e-83	-	-	-	S	-	-	-	COG NOG32209 non supervised orthologous group
HPMLHGED_00007	6.47e-110	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPMLHGED_00008	1.7e-148	-	-	-	S	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00009	5.96e-110	queF	1.7.1.13	-	H	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HPMLHGED_00010	1.29e-158	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HPMLHGED_00011	5.4e-152	yhhQ	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HPMLHGED_00012	5.64e-59	marR	-	-	K	-	-	-	Winged helix DNA-binding domain
HPMLHGED_00013	8.49e-89	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPMLHGED_00014	4.38e-160	-	-	-	S	-	-	-	KilA-N domain
HPMLHGED_00015	7.04e-302	-	-	-	-	-	-	-	-
HPMLHGED_00016	0.0	chonabc	4.2.2.20, 4.2.2.21	-	N	ko:K08961	-	ko00000,ko01000	Chondroitin sulfate ABC lyase
HPMLHGED_00017	3.95e-122	-	-	-	S	-	-	-	COG NOG28211 non supervised orthologous group
HPMLHGED_00018	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
HPMLHGED_00019	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00020	6.38e-183	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapB family
HPMLHGED_00021	0.0	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	signal peptidase i
HPMLHGED_00022	2.81e-231	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPMLHGED_00023	1.71e-151	-	-	-	C	-	-	-	WbqC-like protein
HPMLHGED_00024	0.0	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
HPMLHGED_00026	0.0	thrA	1.1.1.3, 2.7.2.4	-	E	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HPMLHGED_00027	2.15e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HPMLHGED_00028	2.77e-291	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HPMLHGED_00029	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPMLHGED_00030	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD-dependent
HPMLHGED_00031	4.54e-138	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HPMLHGED_00032	0.0	-	-	-	P	-	-	-	Outer membrane receptor
HPMLHGED_00033	1.88e-121	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00034	1.22e-248	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00035	0.0	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HPMLHGED_00036	1.28e-228	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HPMLHGED_00037	3.02e-21	-	-	-	C	-	-	-	4Fe-4S binding domain
HPMLHGED_00038	7.27e-286	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
HPMLHGED_00039	1.81e-294	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HPMLHGED_00040	0.0	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
HPMLHGED_00041	5.89e-90	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00043	5.22e-255	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 10.00
HPMLHGED_00044	7.52e-165	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPMLHGED_00045	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score 9.49
HPMLHGED_00046	3.42e-129	-	-	-	H	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00047	1.16e-286	-	-	-	S	-	-	-	protein conserved in bacteria
HPMLHGED_00048	0.0	-	-	-	S	-	-	-	Purple acid Phosphatase, N-terminal domain
HPMLHGED_00049	6.34e-263	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HPMLHGED_00050	1.65e-211	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00051	1.39e-297	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_00052	1.18e-195	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
HPMLHGED_00053	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPMLHGED_00054	4.89e-282	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00055	1.46e-217	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
HPMLHGED_00056	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_00058	0.0	-	-	-	S	-	-	-	SWIM zinc finger
HPMLHGED_00059	0.0	-	-	-	G	-	-	-	TRAP-type C4-dicarboxylate transport system periplasmic component
HPMLHGED_00060	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HPMLHGED_00061	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPMLHGED_00062	1.15e-235	-	-	-	M	-	-	-	Peptidase, M23
HPMLHGED_00063	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00064	5.42e-169	-	-	-	T	-	-	-	Response regulator receiver domain
HPMLHGED_00065	0.0	ydaH	-	-	H	ko:K12942	-	ko00000	Psort location CytoplasmicMembrane, score
HPMLHGED_00066	2.01e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_00067	2.84e-241	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_00068	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00069	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_00070	0.0	-	-	-	P	-	-	-	Protein of unknown function (DUF229)
HPMLHGED_00071	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_00073	1.13e-133	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_00074	5.04e-75	-	-	-	-	-	-	-	-
HPMLHGED_00076	3.76e-188	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
HPMLHGED_00078	7.53e-119	-	-	-	K	-	-	-	COG NOG19120 non supervised orthologous group
HPMLHGED_00079	7.81e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00082	0.0	-	-	-	O	-	-	-	non supervised orthologous group
HPMLHGED_00084	0.0	-	-	-	E	-	-	-	B12 binding domain
HPMLHGED_00085	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HPMLHGED_00086	1.43e-107	-	-	-	P	-	-	-	Right handed beta helix region
HPMLHGED_00087	4.46e-87	-	-	-	S	-	-	-	COG NOG30410 non supervised orthologous group
HPMLHGED_00088	4.6e-102	-	-	-	-	-	-	-	-
HPMLHGED_00089	0.0	-	-	-	E	-	-	-	Transglutaminase-like protein
HPMLHGED_00090	1.78e-17	-	-	-	-	-	-	-	-
HPMLHGED_00091	5.88e-164	-	-	-	S	-	-	-	Domain of unknown function (DUF4627)
HPMLHGED_00092	0.0	-	-	-	S	-	-	-	COG NOG25375 non supervised orthologous group
HPMLHGED_00093	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_00094	0.0	-	-	-	T	-	-	-	Sigma-54 interaction domain protein
HPMLHGED_00095	1.62e-294	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00096	8.1e-36	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00097	3.31e-188	-	-	-	Q	-	-	-	Protein of unknown function (DUF1698)
HPMLHGED_00098	0.0	-	-	-	S	-	-	-	COG NOG11656 non supervised orthologous group
HPMLHGED_00099	5.32e-86	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00100	2.19e-209	-	-	-	S	-	-	-	UPF0365 protein
HPMLHGED_00101	8.57e-216	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_00102	1.4e-155	-	-	-	S	ko:K07118	-	ko00000	NmrA-like family
HPMLHGED_00103	1.29e-36	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_00104	9.25e-31	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_00105	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HPMLHGED_00107	1.9e-127	ibrB	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_00108	9.18e-83	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase family
HPMLHGED_00109	5.98e-38	ilvC	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ketol-acid reductoisomerase
HPMLHGED_00110	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00111	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HPMLHGED_00112	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain protein
HPMLHGED_00114	6.64e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_00115	2.96e-212	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_00116	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00117	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HPMLHGED_00118	8.35e-95	-	-	-	E	ko:K03307	-	ko00000	alkaline phosphatase synthesis sensor protein phoR K07636
HPMLHGED_00119	7.09e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HPMLHGED_00120	0.0	ahpF	-	-	C	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase subunit F
HPMLHGED_00122	2.88e-189	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_00123	1.55e-292	-	-	-	C	-	-	-	Oxidoreductase, FAD FMN-binding protein
HPMLHGED_00124	7.48e-186	-	1.3.1.22	-	S	ko:K12343	ko00140,map00140	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00125	1.49e-26	-	-	-	-	-	-	-	-
HPMLHGED_00126	8.8e-155	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_00127	0.0	prpC	2.3.3.1, 2.3.3.5	-	C	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_00128	1.54e-291	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_00129	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_00130	7.95e-92	eamA	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00131	4.22e-210	rhaR_1	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_00132	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HPMLHGED_00133	0.0	-	-	-	S	-	-	-	MAC/Perforin domain
HPMLHGED_00134	6.68e-156	-	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	COG4845 Chloramphenicol O-acetyltransferase
HPMLHGED_00135	9.54e-65	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPMLHGED_00137	9.94e-210	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPMLHGED_00138	1.48e-118	-	-	-	S	ko:K07095	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00140	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HPMLHGED_00141	8.96e-104	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00142	1.22e-307	-	-	-	S	-	-	-	Domain of unknown function (DUF4989)
HPMLHGED_00143	0.0	-	-	-	G	-	-	-	Psort location Extracellular, score 9.71
HPMLHGED_00144	7.22e-284	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
HPMLHGED_00145	3.48e-246	-	-	-	S	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_00146	0.0	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_00147	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00148	7.57e-303	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HPMLHGED_00150	1.75e-143	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_00151	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00152	6.27e-241	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00153	4.9e-54	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_00154	3.33e-271	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HPMLHGED_00155	7.7e-176	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_00156	0.0	-	-	-	-	-	-	-	-
HPMLHGED_00157	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00158	4.45e-89	ompH	-	-	M	ko:K06142	-	ko00000	membrane
HPMLHGED_00159	8.69e-106	ompH	-	-	M	ko:K06142	-	ko00000	membrane
HPMLHGED_00160	0.0	yaeT	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Outer membrane protein assembly complex, YaeT protein
HPMLHGED_00161	6.38e-178	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPMLHGED_00162	0.0	-	-	-	G	-	-	-	COG NOG27066 non supervised orthologous group
HPMLHGED_00163	3.28e-252	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HPMLHGED_00164	1.4e-198	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPMLHGED_00165	2.89e-110	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HPMLHGED_00167	1.58e-210	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00168	0.0	-	-	-	S	-	-	-	Oxidoreductase NAD-binding domain protein
HPMLHGED_00169	0.0	-	-	-	E	-	-	-	COG NOG04153 non supervised orthologous group
HPMLHGED_00170	1.44e-311	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
HPMLHGED_00171	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00172	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00173	7.44e-154	-	-	-	PT	-	-	-	COG NOG28383 non supervised orthologous group
HPMLHGED_00174	1.49e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPMLHGED_00175	0.0	-	-	-	M	-	-	-	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
HPMLHGED_00176	0.0	-	-	-	S	-	-	-	hydrolase activity, acting on glycosyl bonds
HPMLHGED_00177	6.64e-247	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_00178	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HPMLHGED_00179	0.0	-	-	-	S	-	-	-	COG NOG07965 non supervised orthologous group
HPMLHGED_00180	4.88e-196	-	-	-	NU	-	-	-	Protein of unknown function (DUF3108)
HPMLHGED_00181	2.09e-86	paaI	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	phenylacetic acid degradation protein
HPMLHGED_00182	5.83e-252	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_00183	0.0	-	-	-	P	-	-	-	SusD family
HPMLHGED_00184	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00185	0.0	-	-	-	G	-	-	-	IPT/TIG domain
HPMLHGED_00186	4.18e-307	-	-	-	O	-	-	-	Glycosyl Hydrolase Family 88
HPMLHGED_00187	0.0	aslA	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00188	5.29e-221	-	-	-	S	-	-	-	Conjugative transposon TraJ protein
HPMLHGED_00189	2.97e-64	-	-	-	U	-	-	-	COG NOG09946 non supervised orthologous group
HPMLHGED_00190	0.0	-	-	-	G	-	-	-	Putative collagen-binding domain of a collagenase
HPMLHGED_00191	1.91e-303	-	3.2.1.172	GH105	E	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_00192	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
HPMLHGED_00193	2.26e-224	-	1.3.5.2	-	F	ko:K00254	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HPMLHGED_00194	1.7e-191	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPMLHGED_00195	1.69e-125	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HPMLHGED_00196	3.41e-172	yfkO	-	-	C	-	-	-	Nitroreductase family
HPMLHGED_00197	1.94e-191	-	-	-	S	-	-	-	COG4422 Bacteriophage protein gp37
HPMLHGED_00198	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HPMLHGED_00199	0.0	htpG	-	-	T	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00200	0.0	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HPMLHGED_00201	6.3e-251	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HPMLHGED_00202	3.05e-193	deoD	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HPMLHGED_00203	7.19e-282	lpxK	2.7.1.130	-	F	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HPMLHGED_00204	0.0	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA, 67K type
HPMLHGED_00205	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_00206	0.0	bglX	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HPMLHGED_00207	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HPMLHGED_00208	8.08e-103	-	-	-	L	-	-	-	ISXO2-like transposase domain
HPMLHGED_00215	2.68e-60	-	-	-	S	-	-	-	Psort location Extracellular, score
HPMLHGED_00216	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
HPMLHGED_00217	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
HPMLHGED_00218	5.19e-222	cysD	2.7.7.4	-	H	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase
HPMLHGED_00219	1.71e-138	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HPMLHGED_00220	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00221	4.2e-192	cysQ	3.1.3.7	-	P	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	ko00000,ko00001,ko01000,ko03016	3'(2'),5'-bisphosphate nucleotidase
HPMLHGED_00222	2.12e-89	-	-	-	D	-	-	-	Sporulation and cell division repeat protein
HPMLHGED_00223	1.44e-180	ydfG	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HPMLHGED_00224	8.36e-38	-	-	-	S	-	-	-	COG NOG35214 non supervised orthologous group
HPMLHGED_00225	1.15e-51	-	-	-	S	-	-	-	COG NOG30994 non supervised orthologous group
HPMLHGED_00226	2.27e-49	-	-	-	S	-	-	-	COG NOG35393 non supervised orthologous group
HPMLHGED_00227	3.48e-164	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_00228	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
HPMLHGED_00229	3.71e-172	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HPMLHGED_00231	2.57e-288	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
HPMLHGED_00232	5.35e-278	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00234	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor K01189
HPMLHGED_00235	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMLHGED_00236	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00237	2.87e-30	-	-	-	S	-	-	-	COG NOG34202 non supervised orthologous group
HPMLHGED_00238	1.77e-150	nlpD_2	-	-	M	-	-	-	COG COG0739 Membrane proteins related to metalloendopeptidases
HPMLHGED_00239	2.31e-155	-	-	-	S	-	-	-	B3 4 domain protein
HPMLHGED_00240	3.9e-185	-	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HPMLHGED_00241	1.46e-210	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPMLHGED_00242	2.39e-59	-	-	-	N	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_00243	4.44e-111	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_00244	2.2e-159	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_00245	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00246	1.32e-136	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_00247	6.3e-90	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPMLHGED_00248	1.01e-224	-	3.2.1.14, 3.2.1.4	GH18,GH5,GH9	G	ko:K01179,ko:K01183	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 18 family
HPMLHGED_00249	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00250	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00251	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00252	3.71e-295	-	-	-	M	-	-	-	Domain of unknown function (DUF1735)
HPMLHGED_00254	3.89e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF3822)
HPMLHGED_00255	2.14e-127	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HPMLHGED_00256	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPMLHGED_00257	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HPMLHGED_00258	5.76e-84	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00259	7.16e-257	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPMLHGED_00261	4.63e-187	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
HPMLHGED_00263	0.0	atpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HPMLHGED_00264	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00265	5.09e-195	-	-	-	Q	-	-	-	COG NOG10855 non supervised orthologous group
HPMLHGED_00266	2.23e-77	-	-	-	K	ko:K07506,ko:K13652	-	ko00000,ko03000	Bacterial regulatory helix-turn-helix proteins, AraC family
HPMLHGED_00267	1.4e-44	-	-	-	-	-	-	-	-
HPMLHGED_00268	1.76e-170	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HPMLHGED_00269	1.12e-135	fklB	5.2.1.8	-	G	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
HPMLHGED_00270	2.07e-202	-	5.2.1.8	-	M	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
HPMLHGED_00271	3.43e-106	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator, AsnC family
HPMLHGED_00272	6.29e-71	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00274	2.4e-105	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_00275	0.0	-	-	-	KT	-	-	-	Two component regulator propeller
HPMLHGED_00276	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
HPMLHGED_00277	0.0	-	-	-	S	-	-	-	Serine hydrolase involved in the detoxification of formaldehyde
HPMLHGED_00278	2.82e-189	-	-	-	DT	-	-	-	aminotransferase class I and II
HPMLHGED_00279	2.6e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3037)
HPMLHGED_00280	3.99e-193	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HPMLHGED_00281	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HPMLHGED_00282	1.1e-187	uxuB_1	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_00283	1.55e-295	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HPMLHGED_00284	6.4e-80	-	-	-	-	-	-	-	-
HPMLHGED_00285	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_00286	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
HPMLHGED_00288	0.0	-	-	-	O	-	-	-	COG NOG06109 non supervised orthologous group
HPMLHGED_00289	1.21e-233	-	-	-	S	-	-	-	PKD-like family
HPMLHGED_00290	1.25e-115	-	-	-	S	-	-	-	Domain of unknown function (DUF4843)
HPMLHGED_00291	9.45e-238	-	-	-	J	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_00292	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00293	5.88e-284	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_00295	6.27e-131	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HPMLHGED_00296	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HPMLHGED_00297	2.14e-122	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPMLHGED_00298	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPMLHGED_00299	6.98e-104	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPMLHGED_00300	3.11e-73	ypjD	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HPMLHGED_00301	1.21e-210	deoC	4.1.2.4	-	H	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPMLHGED_00302	1.24e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF1266)
HPMLHGED_00303	3.12e-225	ispB	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HPMLHGED_00304	1.01e-250	-	-	-	S	-	-	-	COG NOG25022 non supervised orthologous group
HPMLHGED_00305	4.97e-144	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPMLHGED_00306	0.0	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00307	3.89e-22	-	-	-	-	-	-	-	-
HPMLHGED_00308	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HPMLHGED_00309	4.22e-143	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPMLHGED_00310	0.0	leuA_1	2.3.1.182	-	E	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the alpha-IPM synthase homocitrate synthase family
HPMLHGED_00312	1.83e-259	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPMLHGED_00313	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4784)
HPMLHGED_00314	2.63e-155	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HPMLHGED_00315	2.61e-163	ybjG	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00316	0.0	ltaS2	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00317	1.53e-219	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HPMLHGED_00318	3.32e-60	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
HPMLHGED_00319	6.82e-178	-	-	-	M	-	-	-	Acyltransferase family
HPMLHGED_00320	0.0	recQ3	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HPMLHGED_00321	3.16e-102	-	-	-	K	-	-	-	transcriptional regulator (AraC
HPMLHGED_00322	0.0	-	3.4.14.4	-	S	ko:K01277	-	ko00000,ko01000,ko01002	Peptidase family M49
HPMLHGED_00323	4.86e-157	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00324	7.33e-112	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HPMLHGED_00325	5.9e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPMLHGED_00326	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPMLHGED_00327	5.87e-156	-	-	-	S	ko:K06973	-	ko00000	neutral zinc metallopeptidase
HPMLHGED_00328	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HPMLHGED_00329	0.0	-	-	-	S	-	-	-	phospholipase Carboxylesterase
HPMLHGED_00330	1.85e-118	-	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	lipolytic protein G-D-S-L family
HPMLHGED_00332	4.78e-19	-	-	-	-	-	-	-	-
HPMLHGED_00333	1.14e-61	-	-	-	S	-	-	-	Pfam:SusD
HPMLHGED_00334	2.3e-208	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00335	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_00336	8.82e-293	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HPMLHGED_00337	4.1e-80	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00338	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HPMLHGED_00339	4.34e-147	-	-	-	S	-	-	-	Peptidase C14 caspase catalytic subunit p20
HPMLHGED_00340	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score
HPMLHGED_00341	8.18e-269	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HPMLHGED_00342	2.07e-262	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPMLHGED_00343	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00344	0.0	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
HPMLHGED_00345	8.49e-150	sodB	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HPMLHGED_00346	4.95e-263	-	-	-	M	-	-	-	COG3209 Rhs family protein
HPMLHGED_00347	8.83e-89	batD	-	-	S	-	-	-	COG NOG06393 non supervised orthologous group
HPMLHGED_00348	1.43e-186	batE	-	-	T	-	-	-	COG NOG22299 non supervised orthologous group
HPMLHGED_00350	6.54e-63	-	-	-	S	-	-	-	COG NOG19094 non supervised orthologous group
HPMLHGED_00351	2.09e-266	uspA	-	-	T	-	-	-	COG0589 Universal stress protein UspA and related nucleotide-binding
HPMLHGED_00352	4.95e-284	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_00353	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPMLHGED_00354	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HPMLHGED_00355	6.25e-133	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPMLHGED_00356	2.35e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPMLHGED_00357	8.57e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPMLHGED_00358	2.73e-61	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPMLHGED_00359	1.74e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPMLHGED_00360	5.81e-131	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPMLHGED_00361	4.05e-70	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPMLHGED_00362	1.83e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPMLHGED_00363	2.9e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L30
HPMLHGED_00364	6.99e-94	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HPMLHGED_00365	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPMLHGED_00366	0.0	-	-	-	H	-	-	-	COG NOG06391 non supervised orthologous group
HPMLHGED_00367	1.85e-154	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HPMLHGED_00368	1.53e-308	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
HPMLHGED_00369	4.69e-282	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPMLHGED_00370	3.04e-183	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HPMLHGED_00371	2.34e-106	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_00372	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
HPMLHGED_00373	0.0	-	-	-	G	-	-	-	cog cog3537
HPMLHGED_00374	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_00375	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPMLHGED_00376	2.44e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00377	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPMLHGED_00378	4.69e-208	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx GppA phosphatase family
HPMLHGED_00379	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00380	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HPMLHGED_00381	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_00382	0.0	betC_2	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00383	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5014)
HPMLHGED_00384	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00385	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00386	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HPMLHGED_00387	6.78e-142	hddC	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HPMLHGED_00388	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HPMLHGED_00389	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 31 family
HPMLHGED_00390	3.19e-262	-	-	-	G	-	-	-	Fibronectin type III
HPMLHGED_00391	1.12e-213	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_00392	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00393	6.91e-53	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_00394	5.35e-12	-	-	-	NQ	-	-	-	Bacterial Ig-like domain 2
HPMLHGED_00395	2.9e-84	-	-	-	F	ko:K21572	-	ko00000,ko02000	RagB SusD domain protein
HPMLHGED_00396	9.28e-281	-	-	-	H	-	-	-	TonB-dependent receptor plug
HPMLHGED_00397	2.35e-108	-	-	-	F	ko:K21572	-	ko00000,ko02000	RagB SusD domain protein
HPMLHGED_00398	3.52e-175	-	-	-	P	-	-	-	TonB-dependent receptor plug
HPMLHGED_00400	4.3e-48	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
HPMLHGED_00401	3.05e-90	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_00402	2.28e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_00403	6.98e-78	-	-	-	-	-	-	-	-
HPMLHGED_00404	4.46e-247	ltaE	4.1.2.48	-	E	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00405	1.44e-297	-	-	-	M	-	-	-	COG NOG06295 non supervised orthologous group
HPMLHGED_00406	0.0	eptA	-	-	S	-	-	-	lipid A phosphoethanolamine transferase, associated with polymyxin resistance
HPMLHGED_00407	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00408	4.36e-208	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HPMLHGED_00409	1.12e-192	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
HPMLHGED_00410	1.15e-159	-	-	-	S	-	-	-	HmuY protein
HPMLHGED_00411	0.0	hmuR	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HPMLHGED_00412	0.0	cobN	6.6.1.2	-	H	ko:K02230	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1429 Cobalamin biosynthesis protein CobN and related
HPMLHGED_00413	3.65e-158	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00414	2.6e-135	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_00415	5.06e-68	-	-	-	S	-	-	-	Conserved protein
HPMLHGED_00416	8.4e-51	-	-	-	-	-	-	-	-
HPMLHGED_00418	7.79e-164	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HPMLHGED_00419	1.95e-248	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HPMLHGED_00420	1.63e-258	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
HPMLHGED_00421	6.75e-270	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HPMLHGED_00422	1.3e-283	lolE_1	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
HPMLHGED_00423	0.0	-	-	-	F	-	-	-	Belongs to the D-alanine--D-alanine ligase family
HPMLHGED_00424	1.78e-102	-	-	-	K	-	-	-	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HPMLHGED_00425	2.33e-283	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_00426	1.11e-65	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00427	7.18e-296	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPMLHGED_00428	5.3e-51	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase, delta epsilon subunit, beta-sandwich domain protein
HPMLHGED_00429	5.76e-82	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00430	1.16e-265	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HPMLHGED_00431	1.13e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPMLHGED_00432	4.1e-93	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPMLHGED_00433	1.05e-127	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPMLHGED_00434	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPMLHGED_00435	1.97e-199	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPMLHGED_00436	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
HPMLHGED_00437	0.0	uvrD2	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00438	6.15e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00439	1.72e-54	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
HPMLHGED_00441	3.65e-222	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPMLHGED_00442	1.59e-284	-	-	-	S	-	-	-	Clostripain family
HPMLHGED_00443	1.48e-206	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_00444	1.22e-219	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_00445	3.24e-250	-	-	-	GM	-	-	-	NAD(P)H-binding
HPMLHGED_00446	9.76e-120	-	-	-	S	-	-	-	COG NOG28927 non supervised orthologous group
HPMLHGED_00448	1.97e-161	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPMLHGED_00449	8.67e-257	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00451	0.0	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_00452	2.37e-252	abnA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_00453	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00454	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00455	7.26e-253	-	-	-	-	-	-	-	-
HPMLHGED_00456	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00457	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	COG NOG26302 non supervised orthologous group
HPMLHGED_00458	0.0	-	-	-	M	-	-	-	Sulfatase
HPMLHGED_00459	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
HPMLHGED_00460	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HPMLHGED_00461	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00462	7.01e-296	-	-	-	G	-	-	-	Glycosyl hydrolase family 43
HPMLHGED_00463	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00464	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 2, TIM barrel domain
HPMLHGED_00465	0.0	-	-	-	S	ko:K21557	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00466	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00467	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00468	0.0	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
HPMLHGED_00469	0.0	-	3.2.1.11	GH66	G	ko:K05988	ko00500,map00500	ko00000,ko00001,ko01000	COG NOG34737 non supervised orthologous group
HPMLHGED_00471	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HPMLHGED_00472	1.75e-230	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HPMLHGED_00473	3.58e-262	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPMLHGED_00474	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HPMLHGED_00475	1.68e-175	ftsQ	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Psort location Cytoplasmic, score 8.96
HPMLHGED_00476	2.56e-309	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HPMLHGED_00477	1.26e-220	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
HPMLHGED_00478	2.23e-98	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_00479	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HPMLHGED_00480	9.1e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPMLHGED_00481	4.66e-140	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMLHGED_00482	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
HPMLHGED_00483	5.94e-107	-	-	-	L	-	-	-	COG NOG31286 non supervised orthologous group
HPMLHGED_00484	2.84e-210	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HPMLHGED_00485	3.32e-72	-	-	-	-	-	-	-	-
HPMLHGED_00486	6.88e-169	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HPMLHGED_00487	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPMLHGED_00488	3.05e-76	-	-	-	-	-	-	-	-
HPMLHGED_00489	0.0	scpC	2.8.3.18, 3.1.2.1	-	C	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0427 Acetyl-CoA hydrolase
HPMLHGED_00490	2.64e-127	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
HPMLHGED_00491	1.49e-57	-	-	-	-	-	-	-	-
HPMLHGED_00492	1.03e-98	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_00493	1.92e-129	-	-	-	S	-	-	-	PFAM Formylglycine-generating sulfatase enzyme
HPMLHGED_00494	4.87e-137	-	-	-	S	-	-	-	PFAM Formylglycine-generating sulfatase enzyme
HPMLHGED_00495	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
HPMLHGED_00496	3.42e-314	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
HPMLHGED_00497	2.11e-80	-	-	-	S	-	-	-	COG NOG29403 non supervised orthologous group
HPMLHGED_00499	1.76e-87	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPMLHGED_00500	2.31e-257	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPMLHGED_00501	3.49e-83	-	-	-	-	-	-	-	-
HPMLHGED_00502	7.97e-108	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
HPMLHGED_00503	5.32e-36	-	-	-	-	-	-	-	-
HPMLHGED_00505	2.28e-308	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPMLHGED_00506	1.02e-248	-	-	-	S	-	-	-	Tetratricopeptide repeats
HPMLHGED_00507	1.56e-38	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
HPMLHGED_00508	4.79e-107	-	-	-	-	-	-	-	-
HPMLHGED_00509	8.53e-123	-	-	-	O	-	-	-	Thioredoxin
HPMLHGED_00510	6.16e-137	-	-	-	-	-	-	-	-
HPMLHGED_00511	0.0	-	-	-	H	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_00512	1.47e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HPMLHGED_00513	3.51e-164	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00514	1.97e-174	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HPMLHGED_00515	6.37e-67	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HPMLHGED_00516	1.92e-64	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HPMLHGED_00517	6.33e-157	-	-	-	L	ko:K03424	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00518	1.93e-316	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPMLHGED_00521	1.04e-210	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HPMLHGED_00522	1.06e-192	idnO	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_00523	1.16e-302	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG24911 non supervised orthologous group
HPMLHGED_00524	4.47e-292	-	-	-	-	-	-	-	-
HPMLHGED_00525	5.56e-245	-	-	-	S	-	-	-	Putative binding domain, N-terminal
HPMLHGED_00526	5.97e-316	-	-	-	S	-	-	-	Domain of unknown function (DUF4302)
HPMLHGED_00527	4.76e-213	-	-	-	S	-	-	-	Putative zinc-binding metallo-peptidase
HPMLHGED_00528	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28139 non supervised orthologous group
HPMLHGED_00529	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00530	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00531	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28139 non supervised orthologous group
HPMLHGED_00532	1.02e-229	-	-	-	S	-	-	-	Putative zinc-binding metallo-peptidase
HPMLHGED_00533	1.02e-261	-	-	-	S	-	-	-	Domain of unknown function (DUF4302)
HPMLHGED_00534	2.62e-124	-	-	-	S	-	-	-	Putative binding domain, N-terminal
HPMLHGED_00535	5.17e-244	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HPMLHGED_00536	1.7e-106	pgdA_1	-	-	G	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_00537	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HPMLHGED_00538	1.38e-250	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HPMLHGED_00539	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HPMLHGED_00540	9.87e-112	-	-	-	S	-	-	-	Domain of unknown function (DUF5035)
HPMLHGED_00541	5.62e-184	-	-	-	-	-	-	-	-
HPMLHGED_00542	3.16e-159	yfbT	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HPMLHGED_00543	0.0	fkp	-	-	S	-	-	-	GHMP kinase, N-terminal domain protein
HPMLHGED_00545	6.77e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HPMLHGED_00546	1.05e-58	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HPMLHGED_00547	2.35e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HPMLHGED_00548	1.91e-150	ppaX	3.1.3.18	-	V	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
HPMLHGED_00549	3.6e-209	-	-	-	S	ko:K09973	-	ko00000	GumN protein
HPMLHGED_00550	2.43e-116	mepS	3.4.17.13	-	M	ko:K13694	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
HPMLHGED_00551	2.69e-165	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
HPMLHGED_00552	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00553	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Belongs to the peptidase M16 family
HPMLHGED_00554	8.16e-31	kdsA	2.5.1.55	-	H	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
HPMLHGED_00555	1.45e-110	-	-	-	J	-	-	-	Threonine alanine tRNA ligase second additional domain protein
HPMLHGED_00556	9.81e-149	sanA	-	-	S	ko:K03748	-	ko00000	Psort location CytoplasmicMembrane, score 9.82
HPMLHGED_00557	9.07e-158	-	-	-	S	-	-	-	Domain of unknown function (DUF4919)
HPMLHGED_00558	4.47e-169	-	-	-	E	-	-	-	COG2755 Lysophospholipase L1 and related
HPMLHGED_00559	2.44e-129	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00560	3.5e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HPMLHGED_00561	7.66e-252	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPMLHGED_00562	1.11e-207	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPMLHGED_00563	6.37e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HPMLHGED_00564	6.08e-177	lptB	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score 9.12
HPMLHGED_00565	2.1e-164	mlaE	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00566	2.49e-181	metN	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_00567	1.2e-49	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
HPMLHGED_00568	1.5e-310	tig	-	-	O	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase (trigger factor)
HPMLHGED_00569	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00570	6.52e-208	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00571	2.15e-261	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HPMLHGED_00572	2.36e-218	fabK	1.3.1.9	-	C	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	related to 2-nitropropane dioxygenase
HPMLHGED_00573	3.72e-164	-	-	-	S	-	-	-	COG NOG28261 non supervised orthologous group
HPMLHGED_00574	1.2e-30	-	-	-	S	-	-	-	COG NOG28261 non supervised orthologous group
HPMLHGED_00575	1.18e-126	-	-	-	S	-	-	-	COG NOG28799 non supervised orthologous group
HPMLHGED_00576	1.23e-219	-	-	-	K	-	-	-	COG NOG25837 non supervised orthologous group
HPMLHGED_00577	4.44e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_00578	1.91e-198	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HPMLHGED_00579	0.0	-	-	-	C	-	-	-	cytochrome c peroxidase
HPMLHGED_00580	0.0	-	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HPMLHGED_00581	2.12e-164	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HPMLHGED_00582	2.86e-141	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HPMLHGED_00585	4.78e-308	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPMLHGED_00586	9.78e-231	-	-	-	C	-	-	-	4Fe-4S binding domain
HPMLHGED_00587	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPMLHGED_00588	0.0	-	3.1.6.6	-	P	ko:K01133	-	ko00000,ko01000	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_00589	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00590	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HPMLHGED_00591	2.32e-297	-	-	-	V	-	-	-	MATE efflux family protein
HPMLHGED_00592	6.22e-302	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPMLHGED_00593	2.43e-206	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00594	5.49e-192	ycf	-	-	O	-	-	-	COG COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component
HPMLHGED_00595	5.64e-196	ccp	1.11.1.5	-	C	ko:K00428	-	ko00000,ko01000	Psort location Periplasmic, score
HPMLHGED_00596	3.36e-116	ccp	1.11.1.5	-	C	ko:K00428	-	ko00000,ko01000	Psort location Periplasmic, score
HPMLHGED_00597	4.54e-207	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPMLHGED_00598	1.37e-269	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
HPMLHGED_00600	5.09e-49	-	-	-	KT	-	-	-	PspC domain protein
HPMLHGED_00601	0.0	dnaX	2.7.7.7	-	H	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HPMLHGED_00602	3.57e-62	-	-	-	D	-	-	-	Septum formation initiator
HPMLHGED_00603	1.66e-73	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00604	2.76e-126	-	-	-	M	ko:K06142	-	ko00000	membrane
HPMLHGED_00605	5.49e-42	-	-	-	S	-	-	-	COG NOG35566 non supervised orthologous group
HPMLHGED_00606	1.68e-122	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00607	1.13e-126	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_00608	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_00609	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HPMLHGED_00610	2.05e-147	-	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00611	2.3e-124	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00612	4.06e-209	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPMLHGED_00613	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HPMLHGED_00614	4.91e-131	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_00615	7.42e-176	-	-	-	PT	-	-	-	FecR protein
HPMLHGED_00616	8.58e-268	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00617	2.1e-19	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00618	2.27e-217	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
HPMLHGED_00619	3.97e-59	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMLHGED_00620	1.71e-211	-	-	-	-	-	-	-	-
HPMLHGED_00621	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00622	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HPMLHGED_00623	2.91e-282	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_00624	1.36e-291	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_00625	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00626	3.56e-299	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_00627	4.94e-156	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_00628	4.81e-188	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_00629	1.23e-89	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_00630	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4838)
HPMLHGED_00631	1.09e-308	ampG	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00632	2.03e-254	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	glycosylase
HPMLHGED_00634	3.9e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HPMLHGED_00635	2.57e-90	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_00636	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00637	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00638	0.0	-	-	-	G	-	-	-	pectate lyase K01728
HPMLHGED_00639	1.97e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF3826)
HPMLHGED_00640	3.79e-218	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_00641	0.0	hypBA2	-	-	G	-	-	-	BNR repeat-like domain
HPMLHGED_00642	1.58e-127	-	-	-	E	-	-	-	COG COG1305 Transglutaminase-like enzymes
HPMLHGED_00643	2.4e-71	-	-	-	-	-	-	-	-
HPMLHGED_00644	6.65e-168	hly-III	-	-	S	ko:K11068	-	ko00000,ko02042	membrane protein, hemolysin III homolog
HPMLHGED_00645	1.44e-42	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
HPMLHGED_00646	2.24e-101	-	-	-	-	-	-	-	-
HPMLHGED_00648	3.81e-160	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0120 Ribose 5-phosphate isomerase
HPMLHGED_00651	7.43e-59	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_00652	1.23e-23	-	-	-	-	-	-	-	-
HPMLHGED_00653	3.59e-14	-	-	-	-	-	-	-	-
HPMLHGED_00654	1.22e-249	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00656	3.02e-44	-	-	-	-	-	-	-	-
HPMLHGED_00657	2.71e-54	-	-	-	-	-	-	-	-
HPMLHGED_00658	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00659	1.45e-219	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00660	1.25e-74	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00661	4.88e-72	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00662	3.24e-44	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00663	3.83e-129	aslA	-	-	P	-	-	-	Sulfatase
HPMLHGED_00664	6.59e-284	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HPMLHGED_00666	2.27e-124	-	-	-	M	-	-	-	Spi protease inhibitor
HPMLHGED_00667	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00668	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00669	4.5e-36	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HPMLHGED_00671	8.03e-73	-	-	-	-	-	-	-	-
HPMLHGED_00672	2e-311	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00673	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_00674	4.52e-201	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMLHGED_00675	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00676	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HPMLHGED_00677	0.0	-	-	-	G	-	-	-	beta-galactosidase
HPMLHGED_00678	5.45e-162	-	-	-	K	ko:K07665	ko02020,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPMLHGED_00679	2.55e-304	arlS_1	-	-	T	-	-	-	histidine kinase DNA gyrase B
HPMLHGED_00680	0.0	mgtA	3.6.3.2	-	P	ko:K01531	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score
HPMLHGED_00681	0.0	-	-	-	CO	-	-	-	Thioredoxin-like
HPMLHGED_00682	4.51e-78	-	-	-	-	-	-	-	-
HPMLHGED_00683	5.76e-136	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HPMLHGED_00684	3.73e-68	-	-	-	-	-	-	-	-
HPMLHGED_00686	1.98e-91	-	-	-	-	-	-	-	-
HPMLHGED_00687	0.0	-	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Psort location CytoplasmicMembrane, score
HPMLHGED_00688	2.26e-269	acd	-	-	C	-	-	-	Acyl-CoA dehydrogenase, C-terminal domain
HPMLHGED_00689	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00690	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00691	0.0	-	2.7.13.3	-	T	ko:K02484,ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_00692	2.21e-157	srrA	-	-	K	ko:K07657,ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPMLHGED_00693	3.9e-284	-	-	-	T	-	-	-	COG NOG06399 non supervised orthologous group
HPMLHGED_00694	3.88e-200	-	-	-	S	-	-	-	COG NOG25193 non supervised orthologous group
HPMLHGED_00696	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HPMLHGED_00697	3.57e-205	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_00698	2.6e-185	-	-	-	M	ko:K07001	-	ko00000	Patatin-like phospholipase
HPMLHGED_00699	0.0	-	-	-	Q	-	-	-	cephalosporin-C deacetylase activity
HPMLHGED_00700	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_00701	4.08e-257	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HPMLHGED_00706	0.0	-	-	-	L	-	-	-	DNA primase
HPMLHGED_00712	2.03e-36	-	-	-	-	-	-	-	-
HPMLHGED_00713	3.07e-26	-	-	-	-	-	-	-	-
HPMLHGED_00717	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_00718	5.37e-248	-	-	-	-	-	-	-	-
HPMLHGED_00719	3.79e-20	-	-	-	S	-	-	-	Fic/DOC family
HPMLHGED_00721	3.83e-104	-	-	-	-	-	-	-	-
HPMLHGED_00722	1.77e-187	-	-	-	K	-	-	-	YoaP-like
HPMLHGED_00723	2.62e-126	-	-	-	-	-	-	-	-
HPMLHGED_00724	1.17e-164	-	-	-	-	-	-	-	-
HPMLHGED_00725	1.78e-73	-	-	-	-	-	-	-	-
HPMLHGED_00727	2.11e-131	-	-	-	CO	-	-	-	Redoxin family
HPMLHGED_00728	1.47e-170	cypM_1	-	-	H	-	-	-	Methyltransferase domain protein
HPMLHGED_00729	7.45e-33	-	-	-	-	-	-	-	-
HPMLHGED_00730	1.41e-103	-	-	-	-	-	-	-	-
HPMLHGED_00731	1.41e-103	-	-	-	-	-	-	-	-
HPMLHGED_00732	7.45e-33	-	-	-	-	-	-	-	-
HPMLHGED_00733	1.47e-170	cypM_1	-	-	H	-	-	-	Methyltransferase domain protein
HPMLHGED_00734	2.11e-131	-	-	-	CO	-	-	-	Redoxin family
HPMLHGED_00736	1.78e-73	-	-	-	-	-	-	-	-
HPMLHGED_00737	1.17e-164	-	-	-	-	-	-	-	-
HPMLHGED_00738	2.62e-126	-	-	-	-	-	-	-	-
HPMLHGED_00739	1.77e-187	-	-	-	K	-	-	-	YoaP-like
HPMLHGED_00740	3.83e-104	-	-	-	-	-	-	-	-
HPMLHGED_00742	3.79e-20	-	-	-	S	-	-	-	Fic/DOC family
HPMLHGED_00743	5.37e-248	-	-	-	-	-	-	-	-
HPMLHGED_00744	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_00748	3.07e-26	-	-	-	-	-	-	-	-
HPMLHGED_00749	2.03e-36	-	-	-	-	-	-	-	-
HPMLHGED_00755	0.0	-	-	-	L	-	-	-	DNA primase
HPMLHGED_00762	9.39e-130	-	-	-	-	-	-	-	-
HPMLHGED_00768	2.42e-38	-	-	-	-	-	-	-	-
HPMLHGED_00769	0.0	-	-	-	L	-	-	-	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPMLHGED_00770	1.59e-43	-	-	-	-	-	-	-	-
HPMLHGED_00772	3.15e-96	-	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	Peptidase, S49 (Protease IV) family protein
HPMLHGED_00773	7.14e-246	-	-	-	-	-	-	-	-
HPMLHGED_00774	1.33e-111	-	-	-	-	-	-	-	-
HPMLHGED_00778	2.67e-280	-	-	-	-	-	-	-	-
HPMLHGED_00780	9.76e-219	-	-	-	-	-	-	-	-
HPMLHGED_00784	5.84e-55	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00785	4.39e-107	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_00786	2.49e-45	-	-	-	-	-	-	-	-
HPMLHGED_00788	5.48e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF5053)
HPMLHGED_00791	2.48e-18	-	-	-	-	-	-	-	-
HPMLHGED_00798	2.48e-34	-	-	-	-	-	-	-	-
HPMLHGED_00799	1.26e-137	-	-	-	D	-	-	-	nuclear chromosome segregation
HPMLHGED_00800	4.5e-146	-	-	-	-	-	-	-	-
HPMLHGED_00801	1.49e-140	-	-	-	S	-	-	-	cellulase activity
HPMLHGED_00802	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HPMLHGED_00803	1.73e-51	-	-	-	-	-	-	-	-
HPMLHGED_00804	5.16e-17	-	-	-	-	-	-	-	-
HPMLHGED_00806	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HPMLHGED_00807	1.51e-281	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPMLHGED_00808	8.88e-248	lptG	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
HPMLHGED_00809	3.33e-102	-	-	-	O	-	-	-	COG NOG28456 non supervised orthologous group
HPMLHGED_00810	1.49e-241	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPMLHGED_00811	0.0	-	-	-	T	-	-	-	PAS domain S-box protein
HPMLHGED_00812	1.17e-269	-	-	-	N	-	-	-	COG NOG06100 non supervised orthologous group
HPMLHGED_00813	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
HPMLHGED_00814	6.5e-214	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
HPMLHGED_00815	5.4e-309	ybdG_2	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_00816	2.03e-236	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00817	3.19e-202	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00818	6.64e-206	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00819	1.61e-291	-	-	-	GP	ko:K07214	-	ko00000	Putative esterase
HPMLHGED_00820	9.19e-207	-	-	-	G	-	-	-	Glycosyl hydrolases family 35
HPMLHGED_00821	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HPMLHGED_00822	0.0	-	-	-	G	-	-	-	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HPMLHGED_00823	4.62e-13	-	-	-	M	-	-	-	O-Glycosyl hydrolase family 30
HPMLHGED_00824	2.25e-12	-	3.2.1.40	-	N	ko:K05989	-	ko00000,ko01000	domain, Protein
HPMLHGED_00825	4.85e-23	-	-	-	F	ko:K21572	-	ko00000,ko02000	RagB SusD domain protein
HPMLHGED_00826	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
HPMLHGED_00827	6.03e-155	-	3.2.1.20	GH31	S	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HPMLHGED_00828	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_00829	8.45e-219	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_00830	3.82e-255	ypdA_4	-	-	T	-	-	-	Histidine kinase
HPMLHGED_00831	1.31e-164	-	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
HPMLHGED_00832	1.94e-271	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_00833	4.75e-307	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	type I secretion outer membrane protein, TolC family
HPMLHGED_00834	8.29e-51	-	-	-	S	-	-	-	COG NOG17489 non supervised orthologous group
HPMLHGED_00835	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1271 Cytochrome bd-type quinol oxidase, subunit 1
HPMLHGED_00836	1.01e-272	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase subunit 2
HPMLHGED_00837	1.1e-231	hprA	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMLHGED_00838	1.03e-300	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HPMLHGED_00839	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
HPMLHGED_00841	2.21e-255	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HPMLHGED_00842	2e-150	yadS	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00843	2.27e-109	-	-	-	S	-	-	-	COG NOG30135 non supervised orthologous group
HPMLHGED_00844	1.16e-165	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
HPMLHGED_00845	2.02e-145	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the asparaginase 1 family
HPMLHGED_00846	6.26e-292	-	-	-	M	-	-	-	Phosphate-selective porin O and P
HPMLHGED_00847	9.33e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00848	1.05e-132	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Conserved protein
HPMLHGED_00849	2.8e-148	-	-	-	S	-	-	-	COG NOG23394 non supervised orthologous group
HPMLHGED_00850	3.01e-154	-	-	-	M	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_00852	9.52e-75	-	-	-	-	-	-	-	-
HPMLHGED_00853	3.08e-41	-	-	-	M	-	-	-	PFAM Peptidase S41
HPMLHGED_00857	2.17e-122	-	-	-	OT	-	-	-	Forkhead associated domain
HPMLHGED_00858	1.91e-29	-	-	-	T	-	-	-	Forkhead associated domain
HPMLHGED_00859	7.3e-92	-	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	Serine/threonine phosphatases, family 2C, catalytic domain
HPMLHGED_00860	5.75e-102	-	2.7.11.1	-	KLT	ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HPMLHGED_00861	2.57e-129	-	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HPMLHGED_00862	4.46e-61	-	-	-	S	-	-	-	Forkhead associated domain
HPMLHGED_00863	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_00864	2.62e-248	-	-	-	S	-	-	-	UPF0283 membrane protein
HPMLHGED_00865	0.0	-	-	-	S	-	-	-	Dynamin family
HPMLHGED_00866	0.0	-	-	-	K	ko:K03088	-	ko00000,ko03021	Outer membrane protein beta-barrel domain
HPMLHGED_00867	8.08e-188	-	-	-	H	-	-	-	Methyltransferase domain
HPMLHGED_00868	1.08e-286	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00869	4.44e-292	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_00870	5.53e-265	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HPMLHGED_00871	1.27e-133	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPMLHGED_00872	1.07e-149	-	-	-	F	-	-	-	COG COG1051 ADP-ribose pyrophosphatase
HPMLHGED_00873	1.46e-146	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant 1
HPMLHGED_00874	7.33e-39	-	-	-	-	-	-	-	-
HPMLHGED_00875	2.06e-93	-	-	-	-	-	-	-	-
HPMLHGED_00876	2.21e-72	-	-	-	S	-	-	-	Helix-turn-helix domain
HPMLHGED_00877	5.19e-146	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00878	2.69e-204	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HPMLHGED_00879	1.91e-81	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HPMLHGED_00880	6.97e-241	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00881	1.21e-193	rhaT	-	-	EG	ko:K02856	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00882	4.03e-198	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HPMLHGED_00883	9.69e-273	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_00884	6.27e-217	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 9.26
HPMLHGED_00885	1.12e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4890)
HPMLHGED_00887	7.57e-135	qacR	-	-	K	-	-	-	transcriptional regulator, TetR family
HPMLHGED_00888	3.5e-168	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	with different specificities (related to short-chain alcohol
HPMLHGED_00889	1.02e-159	rluC	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	ribosomal pseudouridine synthase C, large subunit
HPMLHGED_00890	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HPMLHGED_00891	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Glycosyl hydrolase family 38 C-terminal domain protein
HPMLHGED_00893	5.5e-169	-	-	-	M	-	-	-	pathogenesis
HPMLHGED_00894	3.58e-183	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HPMLHGED_00896	2.4e-192	-	3.1.3.6, 3.1.4.16	-	M	ko:K01119,ko:K02450,ko:K14197	ko00230,ko00240,ko05150,map00230,map00240,map05150	ko00000,ko00001,ko00002,ko01000,ko02044	LysM domain
HPMLHGED_00897	0.0	-	-	-	-	-	-	-	-
HPMLHGED_00898	2.19e-298	-	3.2.1.197	-	G	ko:K21065	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
HPMLHGED_00899	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
HPMLHGED_00900	2.68e-301	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
HPMLHGED_00901	1.78e-240	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
HPMLHGED_00902	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_00903	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HPMLHGED_00904	2.63e-296	-	-	-	S	-	-	-	IPT/TIG domain
HPMLHGED_00905	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_00906	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HPMLHGED_00907	6.65e-180	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_00908	1.18e-314	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_00910	2.8e-278	yghO	-	-	K	-	-	-	COG NOG07967 non supervised orthologous group
HPMLHGED_00911	1.4e-230	-	-	-	S	-	-	-	PQQ enzyme repeat protein
HPMLHGED_00912	0.000198	-	-	-	-	-	-	-	-
HPMLHGED_00915	5.75e-52	-	-	-	-	-	-	-	-
HPMLHGED_00916	4.52e-47	-	-	-	-	-	-	-	-
HPMLHGED_00918	2.49e-132	-	-	-	S	-	-	-	Phage prohead protease, HK97 family
HPMLHGED_00919	2.62e-257	-	-	-	-	-	-	-	-
HPMLHGED_00920	1.89e-98	-	-	-	-	-	-	-	-
HPMLHGED_00921	5.46e-115	-	-	-	-	-	-	-	-
HPMLHGED_00923	0.0	-	-	-	-	-	-	-	-
HPMLHGED_00927	5.05e-272	-	-	-	-	-	-	-	-
HPMLHGED_00928	6.87e-55	-	-	-	-	-	-	-	-
HPMLHGED_00929	1.82e-121	-	-	-	-	-	-	-	-
HPMLHGED_00930	2.82e-35	-	-	-	-	-	-	-	-
HPMLHGED_00931	3.17e-09	-	-	-	-	-	-	-	-
HPMLHGED_00933	4.85e-123	-	-	-	S	-	-	-	KAP family P-loop domain
HPMLHGED_00934	1.3e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00942	6.98e-70	-	-	-	-	-	-	-	-
HPMLHGED_00943	1.84e-107	-	-	-	-	-	-	-	-
HPMLHGED_00944	0.0	-	-	-	S	-	-	-	Phage-related minor tail protein
HPMLHGED_00945	1.76e-229	-	-	-	-	-	-	-	-
HPMLHGED_00948	6.63e-90	-	-	-	S	-	-	-	Phage minor structural protein
HPMLHGED_00949	1.06e-208	-	-	-	-	-	-	-	-
HPMLHGED_00953	4.38e-84	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_00954	5.53e-129	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_00955	1.52e-109	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_00957	5.7e-48	-	-	-	-	-	-	-	-
HPMLHGED_00958	1.71e-261	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HPMLHGED_00959	2.3e-159	-	-	-	K	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPMLHGED_00960	2.6e-129	ywqN	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00961	4.64e-124	ogt	2.1.1.63	-	H	ko:K00567,ko:K10778	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPMLHGED_00962	1.14e-194	-	2.5.1.105	-	S	ko:K06897	ko00790,map00790	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00963	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
HPMLHGED_00964	1.61e-147	-	-	-	S	-	-	-	Membrane
HPMLHGED_00965	1.22e-192	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMLHGED_00966	0.0	dxs2	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPMLHGED_00967	6e-244	-	-	-	S	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
HPMLHGED_00968	3.17e-135	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00969	2.24e-278	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HPMLHGED_00970	2.54e-216	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_00971	1.79e-215	-	-	-	C	-	-	-	Flavodoxin
HPMLHGED_00972	1.19e-275	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Cupin domain
HPMLHGED_00973	3.39e-209	-	-	-	M	-	-	-	ompA family
HPMLHGED_00974	2.6e-107	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HPMLHGED_00975	2.89e-203	-	-	-	P	ko:K07217	-	ko00000	Manganese containing catalase
HPMLHGED_00976	6.17e-46	-	-	-	-	-	-	-	-
HPMLHGED_00977	1.11e-31	-	-	-	S	-	-	-	Transglycosylase associated protein
HPMLHGED_00978	4.22e-51	-	-	-	S	-	-	-	YtxH-like protein
HPMLHGED_00980	4.82e-147	-	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HPMLHGED_00981	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_00982	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00983	2.07e-280	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_00984	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_00985	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
HPMLHGED_00986	1.45e-167	-	-	-	S	-	-	-	Domain of unknown function (DUF5012)
HPMLHGED_00987	1.6e-119	-	-	-	S	-	-	-	Lipid-binding putative hydrolase
HPMLHGED_00988	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_00989	0.0	-	-	-	H	-	-	-	Susd and RagB outer membrane lipoprotein
HPMLHGED_00990	3.88e-283	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPMLHGED_00991	3.42e-244	-	-	-	JM	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00992	1.03e-17	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
HPMLHGED_00993	1.08e-244	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Psort location Cytoplasmic, score 8.96
HPMLHGED_00994	4.1e-189	etfB	-	-	C	ko:K03521	-	ko00000	COG2086 Electron transfer flavoprotein beta subunit
HPMLHGED_00995	2.64e-269	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_00996	2.97e-308	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_00997	8.62e-137	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_00998	3.39e-78	-	-	-	S	ko:K09790	-	ko00000	Psort location CytoplasmicMembrane, score
HPMLHGED_00999	3.33e-85	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	Psort location Cytoplasmic, score
HPMLHGED_01000	4.48e-136	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HPMLHGED_01001	1.63e-181	-	-	-	C	ko:K18928	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01004	6.67e-120	-	-	-	S	-	-	-	COG NOG28134 non supervised orthologous group
HPMLHGED_01005	1.03e-167	-	-	-	I	-	-	-	COG NOG24984 non supervised orthologous group
HPMLHGED_01006	5.67e-177	-	1.5.1.38, 1.5.1.39	-	C	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
HPMLHGED_01007	0.0	nrd	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HPMLHGED_01008	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.26
HPMLHGED_01009	8.24e-248	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01010	2.09e-243	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_01011	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPMLHGED_01012	6.68e-125	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HPMLHGED_01013	5.02e-256	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family group 2
HPMLHGED_01014	6.88e-210	waaM	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase
HPMLHGED_01015	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score 8.96
HPMLHGED_01016	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score 9.82
HPMLHGED_01017	3.99e-20	-	-	-	S	-	-	-	COG NOG38865 non supervised orthologous group
HPMLHGED_01018	2.73e-209	-	-	-	M	-	-	-	COG COG1082 Sugar phosphate isomerases epimerases
HPMLHGED_01019	2.75e-258	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Right handed beta helix region
HPMLHGED_01020	9.44e-192	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_01021	3.64e-83	-	-	-	S	ko:K06996	-	ko00000	Glyoxalase-like domain
HPMLHGED_01022	2.43e-201	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMLHGED_01023	1.71e-99	-	-	-	K	-	-	-	stress protein (general stress protein 26)
HPMLHGED_01024	8.43e-209	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_01025	0.0	metZ	2.5.1.49	-	E	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01026	5.05e-185	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
HPMLHGED_01027	4.45e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF4369)
HPMLHGED_01028	2.26e-209	-	-	-	M	-	-	-	Putative OmpA-OmpF-like porin family
HPMLHGED_01029	1.07e-190	-	-	-	-	-	-	-	-
HPMLHGED_01030	8.25e-221	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_01031	1.55e-168	-	-	-	K	-	-	-	transcriptional regulator
HPMLHGED_01032	1.47e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMLHGED_01033	7.1e-309	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HPMLHGED_01034	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_01035	1.35e-250	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_01036	1.47e-290	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPMLHGED_01037	3.18e-85	-	-	-	-	-	-	-	-
HPMLHGED_01038	2.2e-146	-	-	-	-	-	-	-	-
HPMLHGED_01039	7.78e-114	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMLHGED_01040	3.14e-181	-	1.1.1.159, 1.3.1.25	-	IQ	ko:K00076,ko:K05783	ko00121,ko00362,ko00364,ko00622,ko01100,ko01120,ko01220,map00121,map00362,map00364,map00622,map01100,map01120,map01220	br01602,ko00000,ko00001,ko00002,ko01000	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_01041	3.05e-235	-	-	-	L	-	-	-	Domain of unknown function (DUF1848)
HPMLHGED_01043	6.08e-194	-	-	-	S	-	-	-	COG NOG27239 non supervised orthologous group
HPMLHGED_01044	1.08e-160	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMLHGED_01045	3.78e-85	-	-	-	S	ko:K06996	-	ko00000	Glyoxalase-like domain
HPMLHGED_01046	1.26e-209	-	-	-	K	ko:K13652	-	ko00000,ko03000	methylphosphotriester-DNA alkyltransferase (AraC XylS family)
HPMLHGED_01047	3.25e-44	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HPMLHGED_01048	7.03e-177	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPMLHGED_01049	5.64e-312	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Aspartate kinase
HPMLHGED_01050	2.88e-307	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HPMLHGED_01051	6.75e-166	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01052	1.95e-221	-	-	-	S	-	-	-	Protein of unknown function (DUF3137)
HPMLHGED_01053	1.2e-158	-	-	-	S	ko:K03744	-	ko00000	LemA family
HPMLHGED_01054	1.09e-283	-	-	-	MO	-	-	-	Bacterial group 3 Ig-like protein
HPMLHGED_01055	3.89e-90	-	-	-	-	-	-	-	-
HPMLHGED_01056	0.0	-	-	-	S	-	-	-	response regulator aspartate phosphatase
HPMLHGED_01057	1.07e-21	-	-	-	S	-	-	-	Domain of unknown function (DUF4907)
HPMLHGED_01058	1.81e-67	nanM	-	-	S	-	-	-	Kelch repeat type 1-containing protein
HPMLHGED_01059	9.89e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
HPMLHGED_01060	1.66e-158	-	-	-	I	-	-	-	COG NOG24984 non supervised orthologous group
HPMLHGED_01061	5.4e-176	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_01062	3.1e-130	-	-	-	KT	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
HPMLHGED_01063	2.37e-70	-	-	-	K	-	-	-	LytTr DNA-binding domain
HPMLHGED_01064	2.57e-12	-	-	-	M	-	-	-	Gram-negative bacterial TonB protein C-terminal
HPMLHGED_01065	3.59e-170	-	-	-	S	ko:K07504	-	ko00000	Type I restriction enzyme HsdR protein N-terminal domain protein
HPMLHGED_01066	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
HPMLHGED_01067	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	COG COG3973 Superfamily I DNA and RNA helicases
HPMLHGED_01068	1e-138	-	-	-	S	-	-	-	COG NOG23385 non supervised orthologous group
HPMLHGED_01069	2.6e-184	-	-	-	K	-	-	-	COG NOG38984 non supervised orthologous group
HPMLHGED_01070	1.29e-64	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
HPMLHGED_01071	2.28e-257	-	-	-	S	-	-	-	Nitronate monooxygenase
HPMLHGED_01072	4.29e-255	rhlE	3.6.4.13	-	JKL	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
HPMLHGED_01073	1.44e-88	cspG	-	-	K	-	-	-	Cold-shock DNA-binding domain protein
HPMLHGED_01074	4.41e-313	-	-	-	G	-	-	-	Glycosyl hydrolase
HPMLHGED_01075	1.04e-171	-	-	-	S	-	-	-	Transposase
HPMLHGED_01076	1.5e-157	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPMLHGED_01077	7.4e-99	-	-	-	S	-	-	-	COG NOG23390 non supervised orthologous group
HPMLHGED_01078	4.44e-120	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HPMLHGED_01079	1.42e-250	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01080	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HPMLHGED_01081	4.96e-72	-	-	-	S	-	-	-	Head fiber protein
HPMLHGED_01082	1.02e-101	-	-	-	-	-	-	-	-
HPMLHGED_01084	9.28e-77	-	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	Helix-turn-helix XRE-family like proteins
HPMLHGED_01085	3.36e-61	-	-	-	S	ko:K19166	-	ko00000,ko01000,ko02048	HigB_toxin, RelE-like toxic component of a toxin-antitoxin system
HPMLHGED_01087	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HPMLHGED_01088	1.89e-264	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit, PBSX family
HPMLHGED_01089	4.86e-95	-	-	-	L	-	-	-	transposase activity
HPMLHGED_01090	5.18e-41	-	-	-	-	-	-	-	-
HPMLHGED_01092	1.64e-188	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HPMLHGED_01093	7.15e-52	-	-	-	-	-	-	-	-
HPMLHGED_01094	0.00091	-	-	-	-	-	-	-	-
HPMLHGED_01096	9.27e-62	-	-	-	-	-	-	-	-
HPMLHGED_01098	2.08e-97	-	-	-	L	-	-	-	DNA-dependent DNA replication
HPMLHGED_01099	3.01e-93	-	-	-	-	-	-	-	-
HPMLHGED_01100	1.73e-43	-	-	-	S	-	-	-	HNH nucleases
HPMLHGED_01101	1.56e-157	-	-	-	-	-	-	-	-
HPMLHGED_01104	4.33e-261	-	-	-	S	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
HPMLHGED_01105	2.22e-89	-	-	-	-	-	-	-	-
HPMLHGED_01112	1.85e-10	-	-	-	-	-	-	-	-
HPMLHGED_01114	2.32e-17	-	-	-	L	-	-	-	NUMOD4 motif
HPMLHGED_01115	1.24e-44	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
HPMLHGED_01116	5.3e-68	-	-	-	K	-	-	-	Transcriptional regulator
HPMLHGED_01117	7.03e-179	-	-	-	S	-	-	-	AAA ATPase domain
HPMLHGED_01119	2.02e-214	nucA_1	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	Psort location Extracellular, score
HPMLHGED_01120	0.0	-	-	-	G	-	-	-	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238
HPMLHGED_01121	3.56e-150	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPMLHGED_01122	1.98e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HPMLHGED_01123	3.8e-251	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
HPMLHGED_01124	8.49e-142	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPMLHGED_01125	2.08e-132	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HPMLHGED_01126	1.59e-185	-	-	-	S	-	-	-	stress-induced protein
HPMLHGED_01127	6.13e-165	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HPMLHGED_01128	1.12e-149	-	-	-	S	-	-	-	COG NOG11645 non supervised orthologous group
HPMLHGED_01130	0.0	algI	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01131	2.44e-80	folK2	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG22185 non supervised orthologous group
HPMLHGED_01132	0.0	mrcA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG5009 Membrane carboxypeptidase penicillin-binding protein
HPMLHGED_01133	1.06e-83	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HPMLHGED_01134	1.23e-276	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01135	2.03e-221	miaA2	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPMLHGED_01136	0.0	-	-	-	P	-	-	-	COG NOG29071 non supervised orthologous group
HPMLHGED_01137	2.06e-278	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01138	4.68e-153	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system ATPase component
HPMLHGED_01139	0.0	-	-	-	S	-	-	-	COG NOG26882 non supervised orthologous group
HPMLHGED_01140	3.05e-170	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPMLHGED_01141	5.4e-120	-	-	-	S	ko:K08999	-	ko00000	Conserved protein
HPMLHGED_01142	9.47e-228	nupG	-	-	G	ko:K03289,ko:K11537	-	ko00000,ko02000	transport of nucleosides, permease protein K03289
HPMLHGED_01143	5.02e-123	-	-	-	S	-	-	-	protein containing a ferredoxin domain
HPMLHGED_01144	1.91e-142	-	3.6.3.21	-	V	ko:K02028,ko:K02068	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HPMLHGED_01145	5.54e-173	-	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01146	4.03e-62	-	-	-	-	-	-	-	-
HPMLHGED_01147	4.69e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF4891)
HPMLHGED_01148	5.73e-264	yqfO	-	-	C	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HPMLHGED_01149	2.27e-155	-	-	-	S	ko:K07164	-	ko00000	Zinc ribbon domain protein
HPMLHGED_01150	0.0	-	-	-	M	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HPMLHGED_01151	2.87e-250	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_01152	1.45e-195	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_01153	0.0	bpeF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_01154	1.65e-106	-	-	-	V	-	-	-	COG NOG14438 non supervised orthologous group
HPMLHGED_01155	7.21e-191	amn	3.2.2.4	-	F	ko:K01241	ko00230,map00230	ko00000,ko00001,ko01000	COG COG0775 Nucleoside phosphorylase
HPMLHGED_01156	6.69e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG1466 DNA polymerase III, delta subunit
HPMLHGED_01158	4.94e-98	-	-	-	K	-	-	-	COG NOG19093 non supervised orthologous group
HPMLHGED_01159	1.34e-186	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HPMLHGED_01160	2.63e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPMLHGED_01161	5.05e-161	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HPMLHGED_01162	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPMLHGED_01163	1.17e-138	-	-	-	G	-	-	-	Domain of unknown function (DUF4450)
HPMLHGED_01164	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_01165	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
HPMLHGED_01166	1.87e-126	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0440 Acetolactate synthase, small (regulatory) subunit
HPMLHGED_01167	8.74e-182	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HPMLHGED_01169	3.29e-205	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPMLHGED_01170	1.34e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPMLHGED_01171	9.25e-269	araJ	-	-	EGP	ko:K08156	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01172	0.0	-	-	-	O	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
HPMLHGED_01173	3.14e-180	-	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain protein
HPMLHGED_01174	7.22e-238	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
HPMLHGED_01175	3.25e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HPMLHGED_01176	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HPMLHGED_01177	1.18e-61	-	-	-	S	-	-	-	IPT/TIG domain
HPMLHGED_01178	0.0	-	-	-	H	-	-	-	cobalamin-transporting ATPase activity
HPMLHGED_01179	7.75e-172	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_01181	9.85e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPMLHGED_01182	3.42e-187	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
HPMLHGED_01183	2.53e-213	-	-	-	M	-	-	-	COG COG1082 Sugar phosphate isomerases epimerases
HPMLHGED_01184	1.16e-84	-	-	-	S	-	-	-	Thiol-activated cytolysin
HPMLHGED_01186	1.71e-91	-	-	-	L	-	-	-	Bacterial DNA-binding protein
HPMLHGED_01187	0.0	-	-	-	JKL	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01188	0.0	ccmC	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01189	2.35e-267	-	-	-	J	-	-	-	endoribonuclease L-PSP
HPMLHGED_01190	7.98e-223	-	-	-	S	-	-	-	unsaturated rhamnogalacturonyl hydrolase activity
HPMLHGED_01191	1.16e-153	vat_2	-	-	S	ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide repeat protein
HPMLHGED_01192	1.58e-205	-	2.1.1.266	-	S	ko:K07115	-	ko00000,ko01000,ko03009	COG COG2961 Protein involved in catabolism of external DNA
HPMLHGED_01193	2.81e-106	lrp	-	-	K	ko:K03719,ko:K05800	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
HPMLHGED_01194	8.28e-310	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01195	7.33e-50	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01196	9.43e-205	mscS	-	-	M	ko:K03442	-	ko00000,ko02000	Small-conductance mechanosensitive channel
HPMLHGED_01197	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
HPMLHGED_01198	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
HPMLHGED_01199	0.0	-	-	-	S	-	-	-	NHL repeat
HPMLHGED_01200	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_01201	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_01202	2.96e-210	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_01203	9.66e-138	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HPMLHGED_01204	1.92e-147	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamine diphosphokinase
HPMLHGED_01205	6.3e-140	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG COG2818 3-methyladenine DNA glycosylase
HPMLHGED_01206	3.27e-314	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HPMLHGED_01207	8.06e-274	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit
HPMLHGED_01208	2.17e-209	-	-	-	S	-	-	-	COG NOG24904 non supervised orthologous group
HPMLHGED_01209	4.43e-251	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
HPMLHGED_01210	1.09e-109	ispF	4.6.1.12	-	H	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HPMLHGED_01211	6.21e-147	fahA	-	-	Q	-	-	-	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828
HPMLHGED_01212	3.17e-157	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HPMLHGED_01213	0.0	-	-	-	S	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_01214	7.79e-78	-	-	-	J	ko:K03113	ko03013,map03013	ko00000,ko00001,ko03012	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related
HPMLHGED_01215	3.5e-225	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPMLHGED_01216	6.56e-188	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HPMLHGED_01217	1.02e-81	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HPMLHGED_01218	1.91e-107	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPMLHGED_01219	8.6e-118	-	-	-	S	-	-	-	COG NOG27649 non supervised orthologous group
HPMLHGED_01220	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HPMLHGED_01221	3.87e-116	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HPMLHGED_01222	2.92e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPMLHGED_01223	2.85e-208	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HPMLHGED_01224	1.89e-158	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HPMLHGED_01225	3.14e-156	-	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_01226	6.58e-227	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HPMLHGED_01227	2.12e-164	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01228	0.0	-	-	-	T	-	-	-	Two component regulator propeller
HPMLHGED_01229	0.0	merA	-	-	C	ko:K21739	-	ko00000	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HPMLHGED_01230	1.17e-132	ykgB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_01231	1.77e-197	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
HPMLHGED_01232	7.97e-108	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HPMLHGED_01233	1.18e-222	lytG	-	-	MNU	-	-	-	COG1705 Muramidase (flagellum-specific)
HPMLHGED_01234	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase, FAD-containing subunit
HPMLHGED_01235	2.6e-279	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HPMLHGED_01236	3.68e-152	ytrE_3	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 7.88
HPMLHGED_01237	6.62e-119	-	-	-	S	-	-	-	COG NOG30399 non supervised orthologous group
HPMLHGED_01238	4.36e-301	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01239	1.17e-308	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_01240	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01241	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01242	4.91e-315	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC K07714
HPMLHGED_01243	1.11e-299	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_01244	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
HPMLHGED_01246	4.33e-154	tal	2.2.1.2	-	F	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPMLHGED_01247	1.97e-257	fbaB	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
HPMLHGED_01248	1.91e-181	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPMLHGED_01249	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
HPMLHGED_01250	0.0	modF	-	-	P	ko:K05776	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC molybdenum transporter, ATP-binding subunit modF
HPMLHGED_01251	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HPMLHGED_01252	2.19e-130	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPMLHGED_01253	5.9e-70	-	-	-	S	-	-	-	COG NOG30624 non supervised orthologous group
HPMLHGED_01255	7.99e-179	-	-	-	S	-	-	-	hydrolases of the HAD superfamily
HPMLHGED_01256	5.79e-43	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01257	1.67e-249	-	-	-	M	-	-	-	Gram-negative bacterial TonB protein C-terminal
HPMLHGED_01258	2.76e-247	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPMLHGED_01259	1.02e-296	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01260	7.78e-165	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPMLHGED_01261	3.7e-297	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
HPMLHGED_01262	4.34e-197	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1/THI5 like
HPMLHGED_01263	1.13e-250	-	-	-	P	-	-	-	phosphate-selective porin O and P
HPMLHGED_01264	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_01265	2.1e-135	maf	-	-	D	ko:K06287	-	ko00000	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
HPMLHGED_01266	1.77e-124	kdsC	3.1.3.45	-	S	ko:K03270	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
HPMLHGED_01267	8.69e-186	-	-	-	S	-	-	-	NADP oxidoreductase coenzyme F420-dependent
HPMLHGED_01268	3.12e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01269	3.22e-120	-	-	-	C	-	-	-	Nitroreductase family
HPMLHGED_01270	3.25e-127	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HPMLHGED_01271	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_01272	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01273	6.24e-245	-	-	-	V	-	-	-	COG NOG22551 non supervised orthologous group
HPMLHGED_01274	2.75e-91	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01275	0.0	mmdA	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HPMLHGED_01276	4.4e-216	-	-	-	C	-	-	-	Lamin Tail Domain
HPMLHGED_01277	9.54e-81	mmdC	-	-	I	-	-	-	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HPMLHGED_01278	2.7e-170	comF	2.4.2.14	-	S	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	ComF family
HPMLHGED_01279	6.12e-197	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01280	1.75e-31	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HPMLHGED_01281	0.0	-	-	-	-	-	-	-	-
HPMLHGED_01282	4.21e-217	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPMLHGED_01283	1.03e-212	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPMLHGED_01284	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01285	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_01286	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4978)
HPMLHGED_01287	1.48e-246	-	-	-	F	-	-	-	Inosine-uridine preferring nucleoside hydrolase
HPMLHGED_01288	2.51e-236	-	-	-	G	ko:K05340	-	ko00000,ko02000	COG NOG04879 non supervised orthologous group
HPMLHGED_01289	3.19e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPMLHGED_01290	3.94e-230	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
HPMLHGED_01291	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HPMLHGED_01292	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HPMLHGED_01293	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HPMLHGED_01294	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_01295	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPMLHGED_01296	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01297	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPMLHGED_01298	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
HPMLHGED_01299	0.0	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01300	8.69e-76	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HPMLHGED_01301	4.98e-16	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
HPMLHGED_01304	8.17e-99	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HPMLHGED_01305	4.43e-56	-	-	-	S	-	-	-	Domain of unknown function (DUF4884)
HPMLHGED_01306	1.52e-296	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_01308	6.43e-139	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_01309	1.1e-121	pepD_1	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HPMLHGED_01310	6.02e-250	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
HPMLHGED_01311	2.01e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPMLHGED_01312	0.0	-	-	-	KT	-	-	-	Transcriptional regulator, AraC family
HPMLHGED_01313	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPMLHGED_01314	0.0	-	-	-	-	-	-	-	-
HPMLHGED_01315	0.0	-	-	-	S	-	-	-	Peptidase of plants and bacteria
HPMLHGED_01316	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_01317	1.71e-121	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_01318	5.46e-64	-	-	-	-	-	-	-	-
HPMLHGED_01322	3.98e-05	-	-	-	-	-	-	-	-
HPMLHGED_01323	8.23e-247	gldB	-	-	O	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01324	1.58e-203	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HPMLHGED_01325	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_01326	7.03e-311	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_01327	0.0	aprN	-	-	M	-	-	-	Belongs to the peptidase S8 family
HPMLHGED_01328	2.24e-281	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPMLHGED_01329	7.52e-36	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPMLHGED_01330	8.01e-256	ilvE	2.6.1.42	-	EH	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
HPMLHGED_01331	1.9e-138	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HPMLHGED_01332	2.44e-209	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPMLHGED_01333	0.0	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	hydrolase family 32
HPMLHGED_01334	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HPMLHGED_01335	1.01e-272	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HPMLHGED_01336	1.54e-215	ydjH_1	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family
HPMLHGED_01337	4.14e-273	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HPMLHGED_01338	8.41e-107	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Nucleoside diphosphate kinase
HPMLHGED_01339	5.55e-211	mepM_1	-	-	M	-	-	-	Peptidase, M23
HPMLHGED_01340	3.31e-123	-	-	-	S	-	-	-	COG NOG27206 non supervised orthologous group
HPMLHGED_01341	3.02e-294	doxX	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01342	3.97e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPMLHGED_01343	4.38e-102	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
HPMLHGED_01344	8.21e-139	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase I
HPMLHGED_01345	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPMLHGED_01346	2.21e-180	tyrA	1.3.1.12	-	E	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HPMLHGED_01347	1.83e-259	pheB	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01348	2.2e-169	dapL	2.6.1.83	-	E	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
HPMLHGED_01349	7.04e-107	-	-	-	-	-	-	-	-
HPMLHGED_01350	1.71e-174	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPMLHGED_01351	1.77e-164	-	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HPMLHGED_01352	2.78e-211	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPMLHGED_01353	1.3e-256	-	-	-	S	-	-	-	Putative oxidoreductase C terminal domain
HPMLHGED_01354	1.84e-129	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPMLHGED_01355	1.07e-314	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HPMLHGED_01356	1.89e-34	-	-	-	-	-	-	-	-
HPMLHGED_01357	0.0	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HPMLHGED_01358	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
HPMLHGED_01359	1.8e-210	-	-	-	S	-	-	-	COG NOG19130 non supervised orthologous group
HPMLHGED_01360	2.9e-254	-	-	-	M	-	-	-	peptidase S41
HPMLHGED_01362	5.17e-219	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01365	3.43e-154	-	-	-	-	-	-	-	-
HPMLHGED_01369	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeats
HPMLHGED_01370	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01371	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF4955)
HPMLHGED_01372	0.0	-	-	-	S	-	-	-	COG NOG38840 non supervised orthologous group
HPMLHGED_01373	7.74e-258	-	-	-	S	-	-	-	Domain of unknown function (DUF5017)
HPMLHGED_01374	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_01375	9.47e-107	-	-	-	K	-	-	-	COG NOG19120 non supervised orthologous group
HPMLHGED_01376	4.77e-64	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01377	3.1e-199	-	1.1.1.384	-	H	ko:K13327	ko00523,ko01130,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Oxidoreductase, NAD-binding domain protein
HPMLHGED_01378	3.51e-61	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenase
HPMLHGED_01379	1.88e-188	-	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase
HPMLHGED_01380	4.42e-51	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LICD family
HPMLHGED_01381	2.45e-133	-	-	-	V	-	-	-	COG NOG25117 non supervised orthologous group
HPMLHGED_01382	1.01e-15	-	-	-	M	-	-	-	LicD family
HPMLHGED_01383	3.19e-34	-	-	-	S	-	-	-	EpsG family
HPMLHGED_01384	4.65e-61	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_01386	3.01e-146	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_01387	5.16e-11	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_01388	1.56e-161	rfaD	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
HPMLHGED_01389	4.6e-185	gmhB	2.7.7.71	-	JM	ko:K15669	ko00540,map00540	ko00000,ko00001,ko01000	Nucleotidyl transferase
HPMLHGED_01390	3.21e-155	-	2.7.1.168	-	S	ko:K07031	ko00540,map00540	ko00000,ko00001,ko01000	GHMP kinase, N-terminal domain protein
HPMLHGED_01391	2.06e-90	-	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	SIS domain
HPMLHGED_01392	6.97e-75	-	-	-	M	-	-	-	glycosyl transferase family 2
HPMLHGED_01393	2.83e-145	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01394	1.06e-170	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HPMLHGED_01395	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
HPMLHGED_01396	4.95e-63	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HPMLHGED_01397	0.0	-	-	-	S	ko:K06921	-	ko00000	ATPase (AAA superfamily)
HPMLHGED_01398	1.09e-256	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPMLHGED_01399	2.33e-283	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HPMLHGED_01400	3.13e-83	-	-	-	O	-	-	-	Glutaredoxin
HPMLHGED_01401	4.78e-289	czcC	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
HPMLHGED_01402	1.65e-255	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_01403	0.0	czcA_1	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_01404	3.73e-300	arlS_2	-	-	T	-	-	-	histidine kinase DNA gyrase B
HPMLHGED_01405	8.58e-162	cusR	-	-	T	ko:K07665	ko02020,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	Transcriptional regulatory protein, C terminal
HPMLHGED_01406	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01407	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_01408	0.0	-	-	-	M	-	-	-	Calpain family cysteine protease
HPMLHGED_01409	4.4e-310	-	-	-	-	-	-	-	-
HPMLHGED_01410	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HPMLHGED_01412	2.29e-251	-	-	-	S	-	-	-	COG NOG26673 non supervised orthologous group
HPMLHGED_01414	2.91e-228	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
HPMLHGED_01415	2.32e-110	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_01416	4.93e-212	-	2.7.4.1	-	S	ko:K22468	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Polyphosphate kinase 2 (PPK2)
HPMLHGED_01417	9.87e-61	-	-	-	-	-	-	-	-
HPMLHGED_01419	3.9e-121	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_01420	3.85e-177	-	-	-	J	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_01421	3.73e-31	-	-	-	-	-	-	-	-
HPMLHGED_01423	1.46e-50	-	-	-	S	-	-	-	COG COG0724 RNA-binding proteins (RRM domain)
HPMLHGED_01424	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
HPMLHGED_01425	3.72e-29	-	-	-	-	-	-	-	-
HPMLHGED_01426	1.19e-171	-	-	-	S	-	-	-	Domain of unknown function (DUF4396)
HPMLHGED_01427	3.39e-194	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPMLHGED_01428	3.44e-262	sucC	6.2.1.5	-	F	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HPMLHGED_01429	7.85e-209	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HPMLHGED_01430	1.44e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase
HPMLHGED_01431	1.03e-171	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01432	0.0	xylB_2	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase, FGGY family protein
HPMLHGED_01433	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01434	0.0	-	-	-	P	ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HPMLHGED_01435	0.0	ramA_2	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01436	6.4e-238	yhiM	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01437	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPMLHGED_01438	2.94e-80	yocK	-	-	T	-	-	-	RNA polymerase-binding protein DksA
HPMLHGED_01439	5.26e-155	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPMLHGED_01440	8.71e-195	-	-	-	S	-	-	-	COG NOG25370 non supervised orthologous group
HPMLHGED_01441	5.29e-87	-	-	-	-	-	-	-	-
HPMLHGED_01442	1.06e-180	aviRb	-	-	J	ko:K03437	-	ko00000,ko03016	RNA methyltransferase, TrmH
HPMLHGED_01443	3.12e-79	-	-	-	K	-	-	-	Penicillinase repressor
HPMLHGED_01444	3.91e-304	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_01445	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
HPMLHGED_01446	1.27e-122	-	-	-	S	-	-	-	COG NOG23374 non supervised orthologous group
HPMLHGED_01447	4.97e-97	-	-	-	S	ko:K15977	-	ko00000	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_01448	1.32e-96	nlpE	-	-	MP	-	-	-	lipoprotein NlpE involved in copper resistance
HPMLHGED_01449	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HPMLHGED_01450	4.14e-55	-	-	-	-	-	-	-	-
HPMLHGED_01451	1.91e-98	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01452	0.0	dtpD	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01453	2.72e-195	vicX	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HPMLHGED_01454	5.39e-69	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HPMLHGED_01455	0.0	-	-	-	G	-	-	-	Carbohydrate binding domain protein
HPMLHGED_01456	5.72e-241	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_01459	1.79e-29	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01460	3.83e-230	-	-	-	S	ko:K01163	-	ko00000	Conserved protein
HPMLHGED_01461	1e-249	-	-	-	S	-	-	-	acetyltransferase involved in intracellular survival and related
HPMLHGED_01462	2.45e-294	-	-	-	E	-	-	-	Glycosyl Hydrolase Family 88
HPMLHGED_01463	0.0	-	-	-	S	-	-	-	COG NOG19133 non supervised orthologous group
HPMLHGED_01464	2.17e-268	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_01465	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_01466	2.18e-215	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_01467	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_01468	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01469	5.47e-296	-	-	-	S	-	-	-	amine dehydrogenase activity
HPMLHGED_01472	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
HPMLHGED_01473	0.0	-	-	-	N	-	-	-	BNR repeat-containing family member
HPMLHGED_01474	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
HPMLHGED_01475	5.04e-238	-	-	-	S	-	-	-	Domain of unknown function (DUF4419)
HPMLHGED_01477	4.11e-255	-	-	-	G	-	-	-	hydrolase, family 43
HPMLHGED_01478	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
HPMLHGED_01479	3.18e-202	-	-	-	M	-	-	-	Domain of unknown function (DUF4488)
HPMLHGED_01480	0.0	-	-	-	G	-	-	-	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HPMLHGED_01481	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_01482	1.36e-184	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMLHGED_01483	2.69e-82	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01484	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPMLHGED_01485	1.41e-260	-	-	-	G	-	-	-	F5/8 type C domain
HPMLHGED_01486	4.01e-153	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01487	1.62e-28	-	-	-	S	-	-	-	COG NOG16623 non supervised orthologous group
HPMLHGED_01488	8.64e-44	frdB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0479 Succinate dehydrogenase fumarate reductase Fe-S protein subunit
HPMLHGED_01489	0.0	-	-	-	P	-	-	-	Sulfatase
HPMLHGED_01490	6e-210	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
HPMLHGED_01491	3.24e-67	-	-	-	S	-	-	-	COG NOG31846 non supervised orthologous group
HPMLHGED_01492	1.73e-204	-	-	-	S	-	-	-	COG NOG26135 non supervised orthologous group
HPMLHGED_01493	1.24e-298	-	-	-	M	-	-	-	COG NOG24980 non supervised orthologous group
HPMLHGED_01494	5.27e-190	-	-	-	S	ko:K06921	-	ko00000	ATPase (AAA superfamily)
HPMLHGED_01495	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
HPMLHGED_01496	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_01497	1.36e-289	-	-	-	CO	-	-	-	amine dehydrogenase activity
HPMLHGED_01498	0.0	-	-	-	H	-	-	-	cobalamin-transporting ATPase activity
HPMLHGED_01499	0.0	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc-type fe3 -hydroxamate transport system, periplasmic component
HPMLHGED_01500	5.73e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_01501	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HPMLHGED_01502	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
HPMLHGED_01503	0.0	-	-	-	K	ko:K03088	-	ko00000,ko03021	DNA-templated transcription, initiation
HPMLHGED_01504	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HPMLHGED_01505	1.17e-257	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HPMLHGED_01506	1.66e-92	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HPMLHGED_01507	4.48e-300	prtC	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HPMLHGED_01508	0.0	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
HPMLHGED_01509	2.59e-78	-	-	-	S	-	-	-	UpxZ family of transcription anti-terminator antagonists
HPMLHGED_01510	1.73e-138	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
HPMLHGED_01512	9.43e-233	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
HPMLHGED_01513	6.53e-89	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF4119)
HPMLHGED_01514	1.04e-82	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
HPMLHGED_01515	2.3e-184	-	-	-	L	-	-	-	COG NOG19076 non supervised orthologous group
HPMLHGED_01516	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF3078)
HPMLHGED_01517	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPMLHGED_01518	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HPMLHGED_01519	6.19e-315	-	-	-	V	-	-	-	MATE efflux family protein
HPMLHGED_01520	0.0	pop	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HPMLHGED_01521	1.76e-160	-	-	-	-	-	-	-	-
HPMLHGED_01522	5.98e-121	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HPMLHGED_01523	1.55e-254	-	-	-	S	-	-	-	of the beta-lactamase fold
HPMLHGED_01524	3.99e-239	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01525	1.19e-72	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HPMLHGED_01526	3.23e-123	paiA	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01527	0.0	-	-	-	P	ko:K03305	-	ko00000	amino acid peptide transporter
HPMLHGED_01528	4.82e-113	ybaK	-	-	H	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPMLHGED_01529	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPMLHGED_01530	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HPMLHGED_01531	1.8e-78	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HPMLHGED_01532	7.61e-218	oxyR	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	Psort location Cytoplasmic, score 9.97
HPMLHGED_01533	1.32e-219	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01534	9.91e-89	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
HPMLHGED_01535	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01536	1.92e-141	ahcY	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HPMLHGED_01537	2.94e-90	-	-	-	-	-	-	-	-
HPMLHGED_01538	2.14e-204	-	-	-	S	-	-	-	COG3943 Virulence protein
HPMLHGED_01539	1.55e-139	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_01540	1.92e-143	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	DNA-damage-inducible protein D
HPMLHGED_01543	7.59e-162	-	-	-	M	-	-	-	COG NOG07608 non supervised orthologous group
HPMLHGED_01544	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPMLHGED_01545	1.17e-141	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01546	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPMLHGED_01547	0.0	-	-	-	CO	-	-	-	COG NOG39333 non supervised orthologous group
HPMLHGED_01548	3.64e-221	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01549	3.82e-304	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01551	3.61e-144	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPMLHGED_01552	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HPMLHGED_01553	5.83e-242	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_01554	1e-80	-	-	-	K	-	-	-	Transcriptional regulator
HPMLHGED_01555	4.02e-121	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
HPMLHGED_01556	8.14e-80	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01559	5.76e-243	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01560	8.08e-171	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01561	3.44e-111	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01562	6.67e-203	-	-	-	S	-	-	-	COG NOG34011 non supervised orthologous group
HPMLHGED_01563	2.55e-130	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01564	6.45e-100	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPMLHGED_01565	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01566	6.01e-86	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
HPMLHGED_01567	5.98e-172	-	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
HPMLHGED_01568	1.06e-299	fprA	1.6.3.4	-	C	ko:K22405	-	ko00000,ko01000	anaerobic nitric oxide reductase flavorubredoxin
HPMLHGED_01569	3.58e-197	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPMLHGED_01570	3.2e-149	yciO	-	-	J	-	-	-	Belongs to the SUA5 family
HPMLHGED_01571	0.0	-	-	-	M	ko:K07289	-	ko00000	protein involved in outer membrane biogenesis
HPMLHGED_01572	0.0	-	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HPMLHGED_01573	5.9e-187	-	-	-	S	-	-	-	of the HAD superfamily
HPMLHGED_01576	0.0	-	-	-	L	-	-	-	COG COG3666 Transposase and inactivated derivatives
HPMLHGED_01577	1.07e-08	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01578	1.58e-270	-	-	-	M	-	-	-	Domain of unknown function
HPMLHGED_01579	5.38e-311	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
HPMLHGED_01580	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HPMLHGED_01581	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01582	7.62e-259	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HPMLHGED_01587	4.4e-50	porA	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid acceptor oxidoreductase, alpha subunit
HPMLHGED_01588	2.28e-249	oorB	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HPMLHGED_01589	2.73e-282	lolE	-	-	M	ko:K09808,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
HPMLHGED_01590	5.86e-68	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPMLHGED_01591	3.94e-126	mdmC	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01593	1.08e-116	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPMLHGED_01594	0.0	-	-	-	EGP	ko:K08169	-	ko00000,ko02000	the major facilitator superfamily
HPMLHGED_01595	0.0	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HPMLHGED_01596	2.7e-38	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HPMLHGED_01597	2.93e-165	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.52
HPMLHGED_01598	0.0	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HPMLHGED_01599	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
HPMLHGED_01600	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_01601	0.0	-	-	-	M	ko:K02014	-	ko00000,ko02000	Psort location OuterMembrane, score 10.00
HPMLHGED_01602	7.08e-142	-	-	-	JM	-	-	-	N-acetylglucosamine-1-phosphate uridyltransferase
HPMLHGED_01603	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_01604	9.87e-69	-	-	-	-	-	-	-	-
HPMLHGED_01605	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01606	8.49e-245	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
HPMLHGED_01607	0.0	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01608	1.2e-175	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HPMLHGED_01609	2.32e-153	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	uracil phosphoribosyltransferase
HPMLHGED_01610	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HPMLHGED_01611	2.1e-122	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_01612	1.24e-120	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_01613	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HPMLHGED_01614	1.68e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPMLHGED_01615	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_01617	6.49e-129	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_01618	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	Psort location Cytoplasmic, score 9.97
HPMLHGED_01619	1.46e-264	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HPMLHGED_01620	6.3e-63	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HPMLHGED_01621	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HPMLHGED_01622	5.4e-278	thiH	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiH
HPMLHGED_01623	6.1e-160	moeZ	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	involved in molybdopterin and thiamine biosynthesis family 2
HPMLHGED_01624	6.22e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase TENI
HPMLHGED_01625	3.91e-125	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HPMLHGED_01626	2.16e-142	-	-	-	S	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_01627	2.59e-303	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HPMLHGED_01628	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01629	1.02e-232	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_01630	1.88e-124	rpoE3	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_01631	1.33e-311	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
HPMLHGED_01632	2.79e-89	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01633	0.0	fucK	2.7.1.5, 2.7.1.51	-	G	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HPMLHGED_01634	2.24e-153	fucA	4.1.1.104	-	G	ko:K22130	-	ko00000,ko01000	L-fuculose-phosphate aldolase, aldolase class II family
HPMLHGED_01635	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HPMLHGED_01636	8.45e-238	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01637	1.87e-88	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HPMLHGED_01639	4.3e-294	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HPMLHGED_01640	1.16e-243	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_01641	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_01642	4.74e-303	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01643	2.99e-248	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_01644	1.34e-190	-	-	-	K	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain protein
HPMLHGED_01645	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_01646	4.17e-124	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1 PfpI family protein
HPMLHGED_01647	3.72e-80	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HPMLHGED_01648	0.0	-	-	-	E	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HPMLHGED_01649	6.22e-242	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPMLHGED_01650	5.57e-104	yvbK	2.3.1.82	-	K	ko:K03827,ko:K18815	-	br01600,ko00000,ko01000,ko01504	Psort location Cytoplasmic, score 8.96
HPMLHGED_01651	1.19e-111	-	-	-	E	-	-	-	Appr-1-p processing protein
HPMLHGED_01652	7.47e-63	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HPMLHGED_01653	1.17e-137	-	-	-	-	-	-	-	-
HPMLHGED_01654	1.82e-311	creD	-	-	V	ko:K06143	-	ko00000	COG COG4452 Inner membrane protein involved in colicin E2 resistance
HPMLHGED_01655	5.33e-63	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HPMLHGED_01656	3.31e-120	-	-	-	Q	-	-	-	membrane
HPMLHGED_01657	4.75e-96	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HPMLHGED_01658	9.52e-301	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01659	1.1e-226	-	-	-	V	ko:K03543	-	ko00000,ko00002,ko02000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
HPMLHGED_01660	0.0	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01661	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_01662	7.61e-51	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01663	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_01664	6.9e-179	dpm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	b-glycosyltransferase, glycosyltransferase family 2 protein
HPMLHGED_01665	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPMLHGED_01666	3.25e-175	-	-	-	-	-	-	-	-
HPMLHGED_01667	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01668	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Psort location Cytoplasmic, score 9.26
HPMLHGED_01669	3.91e-268	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HPMLHGED_01670	1.27e-98	-	-	-	CO	-	-	-	amine dehydrogenase activity
HPMLHGED_01672	7.55e-06	-	-	-	S	-	-	-	NVEALA protein
HPMLHGED_01673	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_01674	3.58e-81	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
HPMLHGED_01675	3.11e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_01676	2.57e-94	-	-	-	-	-	-	-	-
HPMLHGED_01677	3.54e-198	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_01678	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HPMLHGED_01679	1.14e-144	-	-	-	S	-	-	-	COG NOG27441 non supervised orthologous group
HPMLHGED_01680	6.86e-60	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
HPMLHGED_01681	1.65e-141	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01682	2.4e-73	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
HPMLHGED_01683	1.95e-250	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01684	1.33e-159	-	-	-	S	ko:K07025	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01685	1.62e-182	-	-	-	K	-	-	-	helix_turn_helix, Lux Regulon
HPMLHGED_01686	7.34e-157	-	-	-	S	ko:K09702	-	ko00000	Protein of unknown function (DUF1349)
HPMLHGED_01687	1.61e-252	-	-	-	S	-	-	-	COG NOG15865 non supervised orthologous group
HPMLHGED_01688	5.38e-290	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPMLHGED_01689	1.48e-133	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPMLHGED_01690	1.28e-165	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
HPMLHGED_01691	3.2e-249	-	-	-	M	-	-	-	Peptidase, M28 family
HPMLHGED_01692	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_01693	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
HPMLHGED_01694	1.52e-286	mro_1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPMLHGED_01695	5.52e-224	-	-	-	S	ko:K09924	-	ko00000	COG NOG19128 non supervised orthologous group
HPMLHGED_01696	2.83e-34	-	-	-	-	-	-	-	-
HPMLHGED_01701	2.17e-286	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HPMLHGED_01702	1.45e-257	argE	3.5.1.16	-	E	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
HPMLHGED_01703	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HPMLHGED_01704	0.0	-	-	-	S	-	-	-	Peptidase M16 inactive domain
HPMLHGED_01705	4.46e-227	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPMLHGED_01706	2.39e-18	-	-	-	-	-	-	-	-
HPMLHGED_01707	1.62e-256	-	-	-	P	-	-	-	phosphate-selective porin
HPMLHGED_01708	5.46e-108	cyaA	4.6.1.1	-	S	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_01709	2.79e-293	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01710	1.98e-65	-	-	-	K	-	-	-	sequence-specific DNA binding
HPMLHGED_01711	4e-243	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	Psort location Cytoplasmic, score 8.96
HPMLHGED_01712	6.01e-67	-	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
HPMLHGED_01713	1.59e-155	-	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
HPMLHGED_01714	1.33e-256	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
HPMLHGED_01715	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01716	5.06e-196	-	-	-	S	-	-	-	PFAM nucleic acid binding, OB-fold, tRNA
HPMLHGED_01717	0.0	-	-	-	S	-	-	-	PFAM nucleic acid binding, OB-fold, tRNA
HPMLHGED_01718	1.12e-209	-	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	COG1864 DNA RNA endonuclease G, NUC1
HPMLHGED_01719	3.93e-99	-	-	-	-	-	-	-	-
HPMLHGED_01721	1.29e-96	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Involved in allosteric regulation of aspartate carbamoyltransferase
HPMLHGED_01722	2.37e-141	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HPMLHGED_01723	1.19e-178	-	-	-	S	-	-	-	COG NOG27381 non supervised orthologous group
HPMLHGED_01724	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_01725	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_01726	1.83e-281	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG2706 3-carboxymuconate cyclase
HPMLHGED_01727	3.5e-70	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
HPMLHGED_01729	0.0	-	-	-	C	-	-	-	PKD domain
HPMLHGED_01730	1.62e-219	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	COG0584 Glycerophosphoryl diester phosphodiesterase
HPMLHGED_01731	0.0	-	-	-	G	ko:K07783	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01732	6.35e-18	-	-	-	-	-	-	-	-
HPMLHGED_01733	4.44e-51	-	-	-	-	-	-	-	-
HPMLHGED_01734	1.39e-61	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, RelE family
HPMLHGED_01735	3.03e-52	-	-	-	K	-	-	-	Helix-turn-helix
HPMLHGED_01736	5.91e-06	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01737	1.14e-21	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HPMLHGED_01738	1.9e-62	-	-	-	K	-	-	-	Helix-turn-helix
HPMLHGED_01739	0.0	-	-	-	S	-	-	-	Virulence-associated protein E
HPMLHGED_01740	5.12e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HPMLHGED_01741	7.91e-91	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_01742	8.71e-25	-	-	-	-	-	-	-	-
HPMLHGED_01743	4.55e-113	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_01744	1.1e-177	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPMLHGED_01745	4.31e-108	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HPMLHGED_01746	0.0	abf2	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase domain protein
HPMLHGED_01747	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
HPMLHGED_01748	0.0	araB	-	-	G	-	-	-	Carbohydrate kinase, FGGY family protein
HPMLHGED_01749	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HPMLHGED_01750	8.1e-168	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HPMLHGED_01751	3.04e-162	-	-	-	F	-	-	-	Hydrolase, NUDIX family
HPMLHGED_01752	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPMLHGED_01753	2.32e-282	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPMLHGED_01754	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Glycosyl hydrolases family 43
HPMLHGED_01755	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_01756	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_01757	1.68e-300	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_01759	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
HPMLHGED_01760	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
HPMLHGED_01762	2.51e-316	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
HPMLHGED_01763	8.43e-184	-	-	-	S	-	-	-	COG NOG26374 non supervised orthologous group
HPMLHGED_01764	6.41e-191	-	-	-	S	-	-	-	COG NOG19137 non supervised orthologous group
HPMLHGED_01765	1.56e-193	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_01766	7.5e-86	-	-	-	-	-	-	-	-
HPMLHGED_01767	5.79e-39	-	-	-	-	-	-	-	-
HPMLHGED_01768	7.99e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, Bacteroides expansion family 1
HPMLHGED_01769	6.57e-226	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_01770	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
HPMLHGED_01771	1.19e-112	-	-	-	L	-	-	-	VirE N-terminal domain protein
HPMLHGED_01772	1.01e-200	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HPMLHGED_01773	1.28e-95	-	-	-	-	-	-	-	-
HPMLHGED_01774	8.43e-126	-	-	-	L	-	-	-	reverse transcriptase
HPMLHGED_01775	5.65e-09	-	-	-	-	-	-	-	-
HPMLHGED_01778	2.28e-219	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01780	3.95e-17	-	-	-	-	-	-	-	-
HPMLHGED_01782	1.74e-122	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01786	2.59e-48	-	-	-	-	-	-	-	-
HPMLHGED_01787	6.6e-55	-	-	-	-	-	-	-	-
HPMLHGED_01788	4.16e-162	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase
HPMLHGED_01789	1.12e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4468) with TBP-like fold
HPMLHGED_01791	9.81e-231	-	-	-	L	-	-	-	Domain of unknown function (DUF4268)
HPMLHGED_01793	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_01795	1.82e-80	-	-	-	-	-	-	-	-
HPMLHGED_01797	1.65e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF3853)
HPMLHGED_01799	5.48e-299	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01801	7.67e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_01802	1.5e-230	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_01804	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01805	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
HPMLHGED_01806	1.92e-287	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_01807	6.74e-288	-	-	-	Q	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_01808	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4419)
HPMLHGED_01809	2.29e-253	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPMLHGED_01811	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
HPMLHGED_01812	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
HPMLHGED_01813	8.65e-226	-	-	-	JM	-	-	-	COG NOG09722 non supervised orthologous group
HPMLHGED_01814	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HPMLHGED_01815	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HPMLHGED_01816	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	bifunctional purine biosynthesis protein PurH
HPMLHGED_01817	5.31e-241	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein, MreB Mrl family
HPMLHGED_01818	5.03e-193	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HPMLHGED_01819	9.96e-109	mreD	-	-	S	-	-	-	rod shape-determining protein MreD
HPMLHGED_01820	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein 2
HPMLHGED_01821	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HPMLHGED_01822	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_01823	5.89e-118	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HPMLHGED_01824	4.41e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPMLHGED_01825	1.9e-314	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HPMLHGED_01826	2.54e-132	iorB	1.2.7.8	-	C	ko:K00180	-	br01601,ko00000,ko01000	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HPMLHGED_01827	0.0	iorA	1.2.7.8	-	C	ko:K00179	-	br01601,ko00000,ko01000	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
HPMLHGED_01828	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01829	0.0	-	-	-	M	-	-	-	COG NOG36677 non supervised orthologous group
HPMLHGED_01830	1.48e-165	-	-	-	MU	-	-	-	COG NOG27134 non supervised orthologous group
HPMLHGED_01831	6.87e-306	-	-	-	M	-	-	-	COG NOG26016 non supervised orthologous group
HPMLHGED_01832	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HPMLHGED_01833	0.0	nqrA	1.6.5.8	-	C	ko:K00346	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HPMLHGED_01834	2.83e-135	agcS	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HPMLHGED_01835	1.52e-150	-	-	-	S	-	-	-	COG NOG25304 non supervised orthologous group
HPMLHGED_01836	0.0	eam	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	KamA family
HPMLHGED_01837	2.94e-298	pbuX	-	-	F	ko:K16345	-	ko00000,ko02000	xanthine permease
HPMLHGED_01838	2.93e-174	-	-	-	S	-	-	-	COG NOG09956 non supervised orthologous group
HPMLHGED_01839	1.53e-213	-	-	-	G	-	-	-	polysaccharide catabolic process
HPMLHGED_01840	0.0	-	-	-	S	-	-	-	NHL repeat
HPMLHGED_01841	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01842	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_01843	6.89e-206	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_01844	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Periplasmic, score
HPMLHGED_01846	1.55e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMLHGED_01847	0.0	-	3.2.1.20	GH31	E	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HPMLHGED_01848	1.22e-141	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HPMLHGED_01850	2.83e-51	-	-	-	-	-	-	-	-
HPMLHGED_01853	1.11e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01854	3.65e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HPMLHGED_01855	5.58e-198	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_01856	0.0	mutA	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	methylmalonyl-CoA mutase small subunit
HPMLHGED_01857	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01858	6.68e-150	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01859	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4206 Outer membrane cobalamin receptor protein
HPMLHGED_01860	2.4e-256	-	-	-	S	-	-	-	COG NOG25284 non supervised orthologous group
HPMLHGED_01861	9.28e-136	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_01862	3.47e-35	-	-	-	-	-	-	-	-
HPMLHGED_01864	5.44e-178	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HPMLHGED_01865	4.61e-316	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HPMLHGED_01866	3.68e-132	-	-	-	T	-	-	-	Cyclic nucleotide-monophosphate binding domain
HPMLHGED_01867	1.18e-180	-	-	-	-	-	-	-	-
HPMLHGED_01868	3.28e-77	vdlC	-	-	S	-	-	-	COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HPMLHGED_01869	1.19e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01870	4.96e-113	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HPMLHGED_01871	6.26e-170	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_01872	3.24e-290	-	-	-	G	-	-	-	Major Facilitator Superfamily
HPMLHGED_01873	1.75e-52	-	-	-	-	-	-	-	-
HPMLHGED_01874	6.05e-121	-	-	-	K	-	-	-	Sigma-70, region 4
HPMLHGED_01875	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_01876	0.0	-	-	-	G	-	-	-	pectate lyase K01728
HPMLHGED_01877	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HPMLHGED_01878	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_01879	5.47e-234	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPMLHGED_01880	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HPMLHGED_01881	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
HPMLHGED_01882	1.99e-145	-	-	-	L	-	-	-	VirE N-terminal domain protein
HPMLHGED_01884	4.36e-311	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HPMLHGED_01885	0.0	-	2.7.7.49	-	H	ko:K00986	-	ko00000,ko01000	Group II intron, maturase-specific domain
HPMLHGED_01886	1.52e-136	pbpC	2.4.1.129	GT51	M	ko:K05367	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	COG4953 Membrane carboxypeptidase penicillin-binding protein PbpC
HPMLHGED_01887	1.1e-277	ynfM	-	-	EGP	ko:K08224	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01888	4.11e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_01889	1.21e-189	-	-	-	S	-	-	-	VIT family
HPMLHGED_01890	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01891	2.8e-105	-	-	-	S	-	-	-	COG NOG27363 non supervised orthologous group
HPMLHGED_01892	2.69e-149	narL	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HPMLHGED_01893	1.53e-266	trmU	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPMLHGED_01894	0.0	-	-	-	M	-	-	-	peptidase S41
HPMLHGED_01895	1.16e-208	-	-	-	S	-	-	-	COG NOG30864 non supervised orthologous group
HPMLHGED_01896	1.46e-197	-	3.1.2.12	CE1	S	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	ko00000,ko00001,ko01000	esterase
HPMLHGED_01897	7.37e-103	-	-	-	S	-	-	-	COG NOG29214 non supervised orthologous group
HPMLHGED_01898	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_01899	2.39e-179	loiP	-	-	M	ko:K07387	-	ko00000,ko01000,ko01002	COG0501 Zn-dependent protease with chaperone function
HPMLHGED_01900	2.03e-290	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
HPMLHGED_01901	8.15e-99	-	-	-	MP	ko:K06079	ko01503,map01503	ko00000,ko00001	COG NOG29769 non supervised orthologous group
HPMLHGED_01902	1.53e-308	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HPMLHGED_01903	0.0	xynBA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_01904	6.59e-291	-	-	-	S	-	-	-	COG NOG07966 non supervised orthologous group
HPMLHGED_01905	3.96e-178	-	-	-	N	-	-	-	Bacterial group 2 Ig-like protein
HPMLHGED_01906	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28394 non supervised orthologous group
HPMLHGED_01907	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01908	3.54e-185	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01909	1.67e-131	-	-	-	KT	-	-	-	COG COG3279 Response regulator of the LytR AlgR family
HPMLHGED_01910	1.95e-22	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
HPMLHGED_01911	1.1e-172	-	-	-	-	-	-	-	-
HPMLHGED_01912	1.58e-152	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HPMLHGED_01913	3.25e-112	-	-	-	-	-	-	-	-
HPMLHGED_01915	1.94e-245	gpr	-	-	C	ko:K19265	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HPMLHGED_01916	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_01917	1.76e-59	-	3.1.3.2	-	S	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	ko00000,ko00001,ko01000	Purple acid phosphatase
HPMLHGED_01918	0.0	mscM	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01919	4.18e-216	yrbG	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger
HPMLHGED_01920	0.0	-	-	-	S	-	-	-	COG NOG30867 non supervised orthologous group
HPMLHGED_01921	2e-303	-	-	-	O	-	-	-	protein conserved in bacteria
HPMLHGED_01922	4.9e-240	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
HPMLHGED_01923	1.46e-127	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
HPMLHGED_01924	0.0	-	-	-	S	-	-	-	IPT TIG domain protein
HPMLHGED_01925	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01926	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_01927	1.79e-244	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_01928	4.93e-165	-	-	-	S	-	-	-	VTC domain
HPMLHGED_01929	8.3e-150	-	-	-	S	-	-	-	Domain of unknown function (DUF4956)
HPMLHGED_01930	4.68e-180	-	-	-	S	-	-	-	Protein of unknown function (DUF2490)
HPMLHGED_01931	0.0	-	-	-	M	-	-	-	CotH kinase protein
HPMLHGED_01932	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase
HPMLHGED_01934	1.07e-134	-	-	-	M	-	-	-	COG NOG27749 non supervised orthologous group
HPMLHGED_01935	1.86e-243	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HPMLHGED_01936	1.24e-298	merA	-	-	C	ko:K21739	-	ko00000	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HPMLHGED_01937	0.0	-	-	-	S	-	-	-	C terminal of Calcineurin-like phosphoesterase
HPMLHGED_01938	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HPMLHGED_01939	2.51e-283	dcuB	-	-	S	ko:K07791,ko:K07792	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_01940	6.58e-159	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_01941	1.4e-144	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HPMLHGED_01942	1.47e-207	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HPMLHGED_01943	8.72e-48	-	-	-	S	-	-	-	COG NOG14112 non supervised orthologous group
HPMLHGED_01944	4.42e-96	-	-	-	J	-	-	-	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HPMLHGED_01945	2.71e-206	-	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPMLHGED_01946	8.16e-36	-	-	-	-	-	-	-	-
HPMLHGED_01947	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_01948	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01949	1.35e-274	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
HPMLHGED_01950	3.9e-154	-	-	-	K	ko:K21556	-	ko00000,ko03000	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPMLHGED_01951	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_01952	3.68e-229	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPMLHGED_01953	2.5e-147	lolA	-	-	M	ko:K03634	-	ko00000	COG NOG19151 non supervised orthologous group
HPMLHGED_01954	4.1e-289	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related
HPMLHGED_01955	7.33e-191	-	-	-	S	-	-	-	COG NOG11650 non supervised orthologous group
HPMLHGED_01956	5.16e-135	-	-	-	S	-	-	-	Domain of unknown function (DUF5034)
HPMLHGED_01957	1.55e-222	-	-	-	-	-	-	-	-
HPMLHGED_01959	1.44e-226	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HPMLHGED_01961	4.34e-201	nlpD_1	-	-	M	-	-	-	Peptidase, M23 family
HPMLHGED_01962	4.84e-125	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPMLHGED_01964	0.0	uvrA1	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPMLHGED_01965	1.51e-80	-	-	-	G	-	-	-	Glycosyl hydrolases family 35
HPMLHGED_01966	1.93e-139	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_01967	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HPMLHGED_01968	0.0	-	-	-	M	-	-	-	Domain of unknown function
HPMLHGED_01969	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_01970	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Starch-binding associating with outer membrane
HPMLHGED_01971	0.0	-	-	-	M	ko:K19519	-	ko00000,ko04516	Domain of unknown function (DUF5108)
HPMLHGED_01972	0.0	-	-	-	M	-	-	-	COG2335, Secreted and surface protein containing fasciclin-like repeats
HPMLHGED_01973	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_01974	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	PFAM SusD family
HPMLHGED_01975	0.0	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_01976	4.83e-146	-	-	-	-	-	-	-	-
HPMLHGED_01979	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_01980	0.0	-	-	-	P	-	-	-	Secretin and TonB N terminus short domain
HPMLHGED_01981	6.18e-237	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
HPMLHGED_01982	5.99e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	ECF sigma factor
HPMLHGED_01983	1.88e-290	-	-	-	K	-	-	-	Outer membrane protein beta-barrel domain
HPMLHGED_01984	6.34e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_01985	1.74e-166	-	-	-	S	-	-	-	COG NOG31568 non supervised orthologous group
HPMLHGED_01986	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HPMLHGED_01987	9.8e-97	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HPMLHGED_01988	1.67e-222	xerC	-	-	D	ko:K04763	-	ko00000,ko03036	Tyrosine recombinase XerC
HPMLHGED_01989	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_01990	2.14e-258	-	-	-	CO	-	-	-	AhpC TSA family
HPMLHGED_01991	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI
HPMLHGED_01992	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_01993	7.16e-300	-	-	-	S	-	-	-	aa) fasta scores E()
HPMLHGED_01995	6.68e-21	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_01996	1.44e-57	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
HPMLHGED_01997	2.21e-126	-	-	-	-	-	-	-	-
HPMLHGED_01998	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_01999	8.18e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HPMLHGED_02000	8.11e-97	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_02002	1.86e-260	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02003	3.85e-256	-	-	-	S	-	-	-	COG NOG26804 non supervised orthologous group
HPMLHGED_02004	0.0	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
HPMLHGED_02005	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_02006	0.0	-	-	-	S	ko:K09704	-	ko00000	Conserved protein
HPMLHGED_02007	5.07e-285	mro_1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPMLHGED_02008	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HPMLHGED_02009	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HPMLHGED_02010	8.57e-145	-	-	-	M	-	-	-	non supervised orthologous group
HPMLHGED_02011	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HPMLHGED_02012	0.0	-	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HPMLHGED_02013	1.02e-119	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin carboxyl carrier protein
HPMLHGED_02014	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
HPMLHGED_02015	4.35e-172	-	-	-	S	-	-	-	protein conserved in bacteria
HPMLHGED_02016	9.43e-152	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_02017	1.76e-118	-	-	-	S	-	-	-	COG NOG29315 non supervised orthologous group
HPMLHGED_02018	6.35e-258	envC	-	-	D	-	-	-	Peptidase, M23
HPMLHGED_02019	4.85e-168	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	Succinate dehydrogenase cytochrome B subunit, b558 family
HPMLHGED_02020	2.96e-123	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_02021	7.87e-187	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HPMLHGED_02022	2.59e-196	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_02024	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPMLHGED_02025	1.09e-226	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_02026	1.53e-128	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_02027	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_02028	0.0	-	-	-	S	-	-	-	GxGYxY sequence motif in domain of unknown function N-terminal
HPMLHGED_02029	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02030	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02031	2.66e-239	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_02032	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
HPMLHGED_02033	1.23e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02034	3.51e-183	znuB	-	-	P	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HPMLHGED_02035	5.95e-92	yjeE	-	-	S	ko:K06925	-	ko00000,ko03016	Psort location Cytoplasmic, score
HPMLHGED_02036	5.6e-45	-	-	-	S	-	-	-	COG NOG34862 non supervised orthologous group
HPMLHGED_02037	1.04e-64	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HPMLHGED_02038	2.52e-85	-	-	-	S	-	-	-	Protein of unknown function DUF86
HPMLHGED_02039	8.37e-314	-	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HPMLHGED_02040	4.07e-221	-	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPMLHGED_02041	1e-308	-	-	-	S	-	-	-	COG NOG26634 non supervised orthologous group
HPMLHGED_02042	2.76e-117	cap	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HPMLHGED_02043	6.95e-300	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02044	0.0	-	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
HPMLHGED_02045	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HPMLHGED_02046	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HPMLHGED_02047	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_02048	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
HPMLHGED_02049	3.33e-241	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_02050	7.24e-247	-	-	-	P	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_02051	4.26e-82	rimN	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HPMLHGED_02052	0.0	clcB	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02053	1.03e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPMLHGED_02054	3.56e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02055	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02056	1.05e-254	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHH family
HPMLHGED_02057	3.42e-149	-	-	-	S	-	-	-	COG NOG30041 non supervised orthologous group
HPMLHGED_02058	0.0	glmM	5.4.2.8	-	G	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02059	3.19e-194	-	-	-	KT	-	-	-	Y_Y_Y domain
HPMLHGED_02061	6.15e-202	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HPMLHGED_02062	1.27e-58	dapE	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02063	5.67e-258	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPMLHGED_02064	2.34e-208	-	-	-	S	-	-	-	COG NOG34575 non supervised orthologous group
HPMLHGED_02065	1.5e-170	-	-	-	-	-	-	-	-
HPMLHGED_02067	1.38e-115	-	-	-	S	-	-	-	HEPN domain
HPMLHGED_02068	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
HPMLHGED_02069	0.0	mutB	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02071	2.15e-156	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG1194 A G-specific DNA glycosylase
HPMLHGED_02072	5.6e-98	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HPMLHGED_02073	1.8e-306	gldE	-	-	S	-	-	-	Gliding motility-associated protein GldE
HPMLHGED_02074	5.62e-142	sfp	-	-	H	-	-	-	Belongs to the P-Pant transferase superfamily
HPMLHGED_02075	5.14e-50	-	-	-	S	-	-	-	Divergent 4Fe-4S mono-cluster
HPMLHGED_02076	2.81e-68	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HPMLHGED_02077	0.0	tnaA	4.1.99.1	-	E	ko:K01667	ko00380,map00380	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02078	1.19e-187	-	-	-	S	-	-	-	Domain of unknown function (DUF4465)
HPMLHGED_02079	0.0	-	-	-	S	-	-	-	COG NOG23380 non supervised orthologous group
HPMLHGED_02080	0.0	-	-	-	H	-	-	-	COG4206 Outer membrane cobalamin receptor protein
HPMLHGED_02081	5.82e-204	-	-	-	S	-	-	-	Cell surface protein
HPMLHGED_02082	0.0	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HPMLHGED_02083	0.0	-	-	-	T	-	-	-	Domain of unknown function (DUF5074)
HPMLHGED_02084	5.26e-122	-	-	-	CO	-	-	-	COG NOG24939 non supervised orthologous group
HPMLHGED_02085	6.61e-83	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02086	0.0	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HPMLHGED_02087	0.0	-	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Carboxyl transferase domain
HPMLHGED_02088	1.85e-90	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin-requiring enzyme
HPMLHGED_02089	0.0	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HPMLHGED_02090	1.25e-72	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HPMLHGED_02091	6.15e-98	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG0462 Phosphoribosylpyrophosphate synthetase
HPMLHGED_02092	4.21e-38	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	phosphatidylinositol-4-phosphate 5-kinase family protein K00889
HPMLHGED_02093	1.8e-308	-	-	-	S	-	-	-	Peptidase M16 inactive domain
HPMLHGED_02094	9.5e-152	kdsB	2.7.7.38	-	H	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HPMLHGED_02095	4.58e-116	-	-	-	M	-	-	-	Dipeptidase
HPMLHGED_02096	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
HPMLHGED_02097	3.58e-283	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02098	5.43e-242	oatA	-	-	I	-	-	-	Acyltransferase family
HPMLHGED_02099	3.11e-141	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPMLHGED_02100	1.52e-194	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
HPMLHGED_02101	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HPMLHGED_02103	0.0	merA	-	-	C	ko:K21739	-	ko00000	COG COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HPMLHGED_02104	3.9e-131	ykgB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02105	7.19e-197	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMLHGED_02106	4.23e-135	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HPMLHGED_02107	1.18e-222	lytG	-	-	MNU	-	-	-	COG1705 Muramidase (flagellum-specific)
HPMLHGED_02108	5.07e-101	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase, FAD-containing subunit
HPMLHGED_02109	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02110	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
HPMLHGED_02111	0.0	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Inositol-3-phosphate synthase
HPMLHGED_02112	2.79e-112	pgpA	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02113	1.7e-106	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02114	1.19e-153	pgsA1	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPMLHGED_02115	5.61e-223	-	-	-	I	-	-	-	Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media
HPMLHGED_02116	1.45e-216	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02117	1.8e-65	-	-	-	K	-	-	-	Fic/DOC family
HPMLHGED_02118	2.09e-113	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02119	9.07e-61	-	-	-	-	-	-	-	-
HPMLHGED_02120	9.82e-299	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_02122	9.89e-84	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HPMLHGED_02123	2.5e-47	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02124	4.83e-277	-	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HPMLHGED_02125	8.7e-257	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPMLHGED_02126	2.71e-298	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPMLHGED_02127	1.4e-234	argF	2.1.3.11, 2.1.3.9	-	E	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HPMLHGED_02128	8.64e-84	glpE	-	-	P	-	-	-	Rhodanese-like protein
HPMLHGED_02129	1.29e-169	-	-	-	S	-	-	-	COG NOG31798 non supervised orthologous group
HPMLHGED_02130	2.12e-275	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02131	2.67e-138	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HPMLHGED_02132	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
HPMLHGED_02133	1.97e-174	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HPMLHGED_02136	1.62e-42	-	-	-	-	-	-	-	-
HPMLHGED_02138	2.95e-89	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02139	1.23e-90	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02140	4.01e-119	-	-	-	S	-	-	-	Uncharacterised nucleotidyltransferase
HPMLHGED_02141	5.2e-121	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HPMLHGED_02142	7.69e-92	-	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPMLHGED_02143	3.67e-105	-	-	-	G	-	-	-	HpcH/HpaI aldolase/citrate lyase family
HPMLHGED_02144	8.49e-18	-	-	-	N	-	-	-	cellulase activity
HPMLHGED_02145	6.7e-48	-	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HPMLHGED_02146	7.15e-86	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02147	1.79e-59	-	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HPMLHGED_02148	6.91e-05	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPMLHGED_02149	4.45e-83	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HPMLHGED_02150	1.42e-67	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPMLHGED_02151	8.6e-102	-	-	-	G	-	-	-	polysaccharide deacetylase
HPMLHGED_02152	1.71e-29	-	-	-	-	-	-	-	-
HPMLHGED_02153	4.07e-48	-	-	-	V	ko:K07011	-	ko00000	Glycosyl transferase, family 2
HPMLHGED_02154	2.53e-35	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HPMLHGED_02155	6.64e-19	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HPMLHGED_02156	0.0	-	-	-	Q	-	-	-	FkbH domain protein
HPMLHGED_02157	8.52e-38	-	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HPMLHGED_02158	3.86e-143	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02159	5.07e-253	-	1.1.1.367	-	GM	ko:K19068	-	ko00000,ko01000	NAD dependent epimerase dehydratase family
HPMLHGED_02160	1.34e-210	-	5.1.3.2	-	M	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Polysaccharide biosynthesis protein
HPMLHGED_02161	2.41e-133	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HPMLHGED_02162	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
HPMLHGED_02163	1.39e-278	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_02164	0.0	czcA	-	-	P	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_02165	1.28e-270	-	-	-	MU	-	-	-	outer membrane efflux protein
HPMLHGED_02166	3.58e-199	-	-	-	-	-	-	-	-
HPMLHGED_02167	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
HPMLHGED_02168	2.17e-163	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02169	3.67e-126	rpoE	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_02170	2.5e-64	-	-	-	S	-	-	-	Domain of unknown function (DUF5056)
HPMLHGED_02171	6.01e-300	cls	-	-	M	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HPMLHGED_02172	8.15e-200	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPMLHGED_02173	2.19e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HPMLHGED_02174	1.62e-111	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	transcriptional regulator, AsnC family
HPMLHGED_02175	0.0	-	-	-	S	-	-	-	IgA Peptidase M64
HPMLHGED_02176	2.61e-133	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02177	4.13e-99	-	-	-	U	ko:K03559	-	ko00000,ko02000	COG NOG14448 non supervised orthologous group
HPMLHGED_02178	6.99e-136	-	-	-	U	-	-	-	COG NOG14449 non supervised orthologous group
HPMLHGED_02179	2.77e-104	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02180	6.95e-104	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
HPMLHGED_02181	1.1e-275	-	-	-	M	-	-	-	Dipeptidase
HPMLHGED_02182	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
HPMLHGED_02183	8.43e-282	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02184	1.28e-240	oatA	-	-	I	-	-	-	Acyltransferase family
HPMLHGED_02185	1.18e-138	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPMLHGED_02186	7.83e-197	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
HPMLHGED_02187	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HPMLHGED_02188	0.0	-	-	-	G	-	-	-	beta-galactosidase
HPMLHGED_02189	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HPMLHGED_02190	2.55e-125	gcvP	1.4.4.2	-	E	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HPMLHGED_02191	4.61e-137	-	-	-	C	-	-	-	Nitroreductase family
HPMLHGED_02192	3.28e-257	hpaIIR	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	COG NOG26934 non supervised orthologous group
HPMLHGED_02193	4.17e-135	yigZ	-	-	S	-	-	-	YigZ family
HPMLHGED_02194	6.74e-307	-	-	-	S	-	-	-	Conserved protein
HPMLHGED_02195	1.21e-213	serA	1.1.1.399, 1.1.1.95	-	C	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMLHGED_02196	7.48e-260	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPMLHGED_02197	5.62e-316	dbpA	3.6.4.13	-	L	ko:K05591	-	ko00000,ko01000,ko03009	ATP-independent RNA helicase DbpA
HPMLHGED_02198	1.05e-310	nqrF	1.6.5.8	-	C	ko:K00351	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
HPMLHGED_02199	3.08e-124	nqrE	1.6.5.8	-	C	ko:K00350	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HPMLHGED_02200	2.3e-142	nqrD	1.6.5.8	-	C	ko:K00349	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HPMLHGED_02201	1.38e-158	nqrC	1.6.5.8	-	C	ko:K00348	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HPMLHGED_02202	6.54e-61	nqrB	1.6.5.8	-	C	ko:K00347	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HPMLHGED_02203	1.88e-101	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HPMLHGED_02204	2.77e-220	-	-	-	G	-	-	-	COG COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
HPMLHGED_02205	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	single-stranded-DNA-specific exonuclease recJ
HPMLHGED_02206	0.0	recQ2	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HPMLHGED_02207	3.73e-169	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02208	1.07e-204	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_02209	1.43e-103	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_02211	1.4e-227	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
HPMLHGED_02212	2.84e-228	-	-	-	G	-	-	-	Phosphodiester glycosidase
HPMLHGED_02213	1.42e-305	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02214	6.38e-251	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
HPMLHGED_02220	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG26302 non supervised orthologous group
HPMLHGED_02221	2.93e-109	-	-	-	C	ko:K18929	-	ko00000	electron transport protein YkgF
HPMLHGED_02222	1.17e-132	lutC	-	-	S	ko:K00782	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02223	3.34e-212	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
HPMLHGED_02224	8.72e-279	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02225	1.32e-280	-	-	-	M	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_02226	3.08e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_02227	0.0	-	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain protein
HPMLHGED_02228	8.08e-26	-	-	-	-	-	-	-	-
HPMLHGED_02230	7.16e-68	-	-	-	K	-	-	-	transcriptional regulator, LuxR family
HPMLHGED_02232	5.45e-53	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_02233	2.97e-154	-	-	-	L	-	-	-	Phage integrase family
HPMLHGED_02234	1.03e-30	-	-	-	-	-	-	-	-
HPMLHGED_02236	2.32e-75	-	-	-	Q	-	-	-	methyltransferase
HPMLHGED_02237	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02238	1.54e-289	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HPMLHGED_02240	2.55e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_02241	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02242	3.86e-261	-	-	-	-	-	-	-	-
HPMLHGED_02243	5.6e-251	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HPMLHGED_02244	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HPMLHGED_02245	0.0	-	-	-	U	-	-	-	COG0457 FOG TPR repeat
HPMLHGED_02246	1.22e-149	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HPMLHGED_02249	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HPMLHGED_02250	3.61e-315	-	-	-	S	-	-	-	tetratricopeptide repeat
HPMLHGED_02251	6.55e-224	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
HPMLHGED_02252	1.32e-183	tonB2	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_02253	1.96e-145	exbD2	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
HPMLHGED_02254	1.57e-134	exbD1	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
HPMLHGED_02255	5.35e-176	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
HPMLHGED_02256	4.57e-94	-	-	-	-	-	-	-	-
HPMLHGED_02257	2.7e-121	-	-	-	S	-	-	-	antirestriction protein
HPMLHGED_02258	2.49e-26	-	-	-	-	-	-	-	-
HPMLHGED_02259	4.38e-118	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HPMLHGED_02261	1.59e-65	-	-	-	-	-	-	-	-
HPMLHGED_02262	2.38e-94	-	-	-	S	-	-	-	conserved protein found in conjugate transposon
HPMLHGED_02267	4.18e-285	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02268	4.63e-130	-	-	-	S	-	-	-	Flavodoxin-like fold
HPMLHGED_02269	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_02270	1.84e-303	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_02272	0.0	ctp	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HPMLHGED_02273	4.83e-133	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02274	2.16e-199	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HPMLHGED_02275	8.02e-59	-	-	-	S	-	-	-	COG NOG38282 non supervised orthologous group
HPMLHGED_02276	1.03e-264	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPMLHGED_02277	3.46e-144	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_02278	1.13e-118	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HPMLHGED_02279	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Psort location CytoplasmicMembrane, score
HPMLHGED_02280	5.59e-90	divK	-	-	T	-	-	-	Response regulator receiver domain protein
HPMLHGED_02281	0.0	-	-	-	H	-	-	-	COG NOG26372 non supervised orthologous group
HPMLHGED_02282	2.57e-215	-	-	-	NPU	-	-	-	Psort location OuterMembrane, score 9.49
HPMLHGED_02283	1.32e-05	-	-	-	G	-	-	-	GHMP kinase
HPMLHGED_02286	4.64e-268	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HPMLHGED_02287	6.66e-235	-	-	-	M	-	-	-	NAD dependent epimerase dehydratase family
HPMLHGED_02288	1.01e-284	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
HPMLHGED_02289	0.0	-	-	-	S	-	-	-	Parallel beta-helix repeats
HPMLHGED_02290	0.0	-	-	-	G	-	-	-	Alpha-L-rhamnosidase
HPMLHGED_02291	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02292	0.0	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HPMLHGED_02293	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5121)
HPMLHGED_02294	4.86e-131	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02295	1.39e-149	rnd	-	-	L	-	-	-	3'-5' exonuclease
HPMLHGED_02296	4.98e-295	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SAM-dependent
HPMLHGED_02297	2.12e-91	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
HPMLHGED_02299	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02300	0.0	-	-	-	P	ko:K21573	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02302	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_02303	8.96e-123	-	-	-	S	-	-	-	COG NOG28695 non supervised orthologous group
HPMLHGED_02304	1.14e-287	-	4.2.2.7	PL13	M	ko:K19050	-	ko00000,ko01000	Heparin lyase
HPMLHGED_02305	4.95e-98	-	-	-	S	-	-	-	COG NOG31508 non supervised orthologous group
HPMLHGED_02306	5.15e-125	-	-	-	S	-	-	-	COG NOG31242 non supervised orthologous group
HPMLHGED_02307	3.95e-53	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	COG1760 L-serine deaminase
HPMLHGED_02309	6.67e-191	-	-	-	C	-	-	-	radical SAM domain protein
HPMLHGED_02310	0.0	-	-	-	L	-	-	-	Psort location OuterMembrane, score
HPMLHGED_02311	2.98e-129	-	-	-	S	-	-	-	COG NOG14459 non supervised orthologous group
HPMLHGED_02312	1.32e-73	spoU	-	-	J	-	-	-	RNA methylase, SpoU family K00599
HPMLHGED_02313	3.19e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HPMLHGED_02314	3.78e-57	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPMLHGED_02315	1.79e-91	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HPMLHGED_02316	0.0	-	-	-	G	-	-	-	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HPMLHGED_02317	8.07e-284	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02318	1.25e-281	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_02320	1.76e-63	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMLHGED_02321	1.44e-277	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02322	1.7e-210	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_02323	0.0	-	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HPMLHGED_02324	5.04e-280	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02325	4.47e-228	-	-	-	M	-	-	-	Pfam:DUF1792
HPMLHGED_02326	4.33e-281	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HPMLHGED_02327	1.21e-288	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02328	9.22e-211	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_02329	0.0	-	-	-	S	-	-	-	Putative polysaccharide deacetylase
HPMLHGED_02330	2.4e-277	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02331	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02332	2.23e-258	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family protein
HPMLHGED_02333	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_02334	0.0	-	-	-	S	ko:K15738	-	ko00000,ko02000	ATP-binding cassette protein, ChvD family
HPMLHGED_02335	2.64e-165	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
HPMLHGED_02336	9.82e-234	yfeX	-	-	P	ko:K07223	-	ko00000	Dyp-type peroxidase family
HPMLHGED_02337	1.51e-170	yoqW	-	-	E	-	-	-	SOS response associated peptidase (SRAP)
HPMLHGED_02338	5.22e-162	-	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
HPMLHGED_02339	1.28e-252	cheA	-	-	T	-	-	-	two-component sensor histidine kinase
HPMLHGED_02340	1.48e-223	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HPMLHGED_02341	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HPMLHGED_02342	1.32e-288	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_02343	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_02344	3.48e-128	-	-	-	K	-	-	-	RNA polymerase sigma-70 factor, ECF subfamily
HPMLHGED_02345	1.64e-42	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_02346	9.04e-204	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_02347	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02348	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02349	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
HPMLHGED_02350	2.85e-292	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
HPMLHGED_02351	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
HPMLHGED_02352	8.31e-315	-	-	-	M	-	-	-	Glycosyl hydrolase family 76
HPMLHGED_02354	1.05e-87	pepX2	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
HPMLHGED_02355	9.61e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HPMLHGED_02356	5.44e-232	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02357	5.91e-133	mug	-	-	L	-	-	-	COG3663 G T U mismatch-specific DNA glycosylase
HPMLHGED_02358	1.51e-80	-	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HPMLHGED_02359	6.64e-108	yihY	-	-	S	ko:K07058	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02360	3.01e-114	-	-	-	C	-	-	-	Nitroreductase family
HPMLHGED_02361	1.65e-140	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	COG0307 Riboflavin synthase alpha chain
HPMLHGED_02363	1.51e-202	-	-	-	T	-	-	-	GHKL domain
HPMLHGED_02364	3.25e-154	-	-	-	K	-	-	-	Response regulator receiver domain protein
HPMLHGED_02365	2.12e-155	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HPMLHGED_02366	4.83e-177	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPMLHGED_02367	2.31e-199	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02368	1.17e-271	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HPMLHGED_02369	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
HPMLHGED_02370	1.06e-261	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HPMLHGED_02371	1.93e-210	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_02372	8.03e-288	-	-	-	MU	-	-	-	COG NOG26656 non supervised orthologous group
HPMLHGED_02373	2.5e-205	-	-	-	M	ko:K01993	-	ko00000	COG COG0845 Membrane-fusion protein
HPMLHGED_02374	0.0	-	-	-	G	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_02375	6.84e-237	ybhS	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02376	2.39e-255	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02377	2.2e-85	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HPMLHGED_02378	0.0	-	-	-	N	-	-	-	Leucine rich repeats (6 copies)
HPMLHGED_02379	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02380	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HPMLHGED_02381	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02382	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5010)
HPMLHGED_02384	1.52e-31	pglE	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
HPMLHGED_02386	7.29e-182	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Mannose-1-phosphate guanylyltransferase
HPMLHGED_02387	2.74e-30	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HPMLHGED_02388	1.79e-265	-	4.1.3.39	-	E	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	br01602,ko00000,ko00001,ko00002,ko01000	HMGL-like
HPMLHGED_02389	5.12e-132	-	2.7.7.43	-	M	ko:K00983	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Cytidylyltransferase
HPMLHGED_02390	2.69e-207	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HPMLHGED_02392	6.79e-77	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HPMLHGED_02394	2.14e-64	-	-	-	S	-	-	-	Pfam Glycosyl transferase family 2
HPMLHGED_02395	7.36e-08	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
HPMLHGED_02396	1.52e-71	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPMLHGED_02397	1.17e-73	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_02398	3.93e-78	-	2.3.1.209	-	S	ko:K21379	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HPMLHGED_02399	8.32e-57	-	-	-	S	-	-	-	GlcNAc-PI de-N-acetylase
HPMLHGED_02400	3.15e-39	-	-	-	M	-	-	-	Bacterial sugar transferase
HPMLHGED_02401	1.29e-258	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HPMLHGED_02402	2.59e-255	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HPMLHGED_02403	4.95e-87	-	-	-	S	-	-	-	EcsC protein family
HPMLHGED_02404	1.62e-173	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HPMLHGED_02405	5.34e-42	-	-	-	-	-	-	-	-
HPMLHGED_02406	5.42e-174	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure
HPMLHGED_02407	4.57e-135	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02408	2.17e-213	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HPMLHGED_02409	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HPMLHGED_02410	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_02411	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HPMLHGED_02412	0.0	-	-	-	T	-	-	-	Response regulator receiver domain
HPMLHGED_02413	1.52e-201	-	-	-	E	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HPMLHGED_02414	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_02415	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
HPMLHGED_02416	0.0	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_02417	5.27e-154	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HPMLHGED_02418	0.0	xynB_10	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_02419	1.1e-79	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02420	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02421	5.23e-229	-	-	-	M	-	-	-	F5/8 type C domain
HPMLHGED_02422	0.0	-	-	-	K	-	-	-	GxGYxY sequence motif in domain of unknown function N-terminal
HPMLHGED_02423	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HPMLHGED_02426	4.16e-196	-	-	-	ET	-	-	-	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
HPMLHGED_02427	0.0	-	-	-	H	-	-	-	COG NOG07963 non supervised orthologous group
HPMLHGED_02428	1.82e-125	porG	1.2.7.3	-	C	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit
HPMLHGED_02429	3.43e-187	vorA	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
HPMLHGED_02430	1.44e-31	-	-	-	-	-	-	-	-
HPMLHGED_02431	1.88e-251	vorB	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HPMLHGED_02432	3.12e-38	oorD	1.2.7.3	-	C	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	4Fe-4S binding domain protein
HPMLHGED_02433	1.77e-61	-	-	-	S	-	-	-	TPR repeat
HPMLHGED_02434	0.0	ravA_1	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPMLHGED_02435	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02436	2.91e-43	-	-	-	S	ko:K09793	-	ko00000	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02437	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
HPMLHGED_02439	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HPMLHGED_02440	2.1e-218	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02441	1.48e-135	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPMLHGED_02442	1.51e-178	-	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	COG COG1360 Flagellar motor protein
HPMLHGED_02443	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HPMLHGED_02444	7.52e-101	rsmI_1	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score 8.96
HPMLHGED_02445	2.97e-266	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02446	2.55e-212	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HPMLHGED_02447	0.0	dpp	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
HPMLHGED_02448	4.02e-212	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HPMLHGED_02449	2.67e-39	-	-	-	S	-	-	-	COG NOG17292 non supervised orthologous group
HPMLHGED_02450	2.32e-67	-	-	-	-	-	-	-	-
HPMLHGED_02451	8.92e-84	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
HPMLHGED_02452	0.0	-	-	-	KT	-	-	-	COG NOG25147 non supervised orthologous group
HPMLHGED_02453	0.0	-	-	-	KT	-	-	-	COG NOG25147 non supervised orthologous group
HPMLHGED_02454	0.0	-	-	-	KT	-	-	-	COG NOG25147 non supervised orthologous group
HPMLHGED_02455	1.04e-99	-	-	-	-	-	-	-	-
HPMLHGED_02456	9.66e-221	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPMLHGED_02457	1.95e-122	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02458	6.14e-161	lpxA	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPMLHGED_02459	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HPMLHGED_02460	9.53e-164	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPMLHGED_02461	9.77e-297	-	-	-	S	ko:K06885	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02462	1.99e-196	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HPMLHGED_02463	1.07e-262	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPMLHGED_02464	1.46e-285	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_02466	1.53e-128	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HPMLHGED_02467	6.87e-198	-	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HPMLHGED_02468	2.4e-232	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
HPMLHGED_02469	1.15e-182	aroE	1.1.1.25	-	C	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG0169 Shikimate 5-dehydrogenase
HPMLHGED_02470	2.93e-179	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HPMLHGED_02471	7.73e-230	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HPMLHGED_02472	5.22e-231	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
HPMLHGED_02473	4.33e-162	-	-	-	S	-	-	-	COG NOG26960 non supervised orthologous group
HPMLHGED_02474	7.76e-238	yqiK	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH Band 7 PHB domain protein
HPMLHGED_02475	3.2e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02476	5.42e-254	-	-	-	DK	-	-	-	Fic/DOC family
HPMLHGED_02479	1.27e-221	-	-	-	-	-	-	-	-
HPMLHGED_02480	3.34e-125	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HPMLHGED_02481	6.26e-45	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HPMLHGED_02483	1.35e-60	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HPMLHGED_02484	1.68e-38	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
HPMLHGED_02485	9.56e-289	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
HPMLHGED_02486	2.47e-311	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_02487	4.34e-151	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02488	9.61e-23	-	-	-	S	-	-	-	Phage derived protein Gp49-like (DUF891)
HPMLHGED_02489	7.13e-36	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMLHGED_02490	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HPMLHGED_02491	3.51e-141	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HPMLHGED_02492	3.05e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF5033)
HPMLHGED_02493	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HPMLHGED_02494	0.0	-	-	-	PT	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02495	3.16e-50	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HPMLHGED_02496	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HPMLHGED_02497	0.0	-	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HPMLHGED_02498	1.35e-201	-	5.2.1.8	-	M	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPMLHGED_02499	9.08e-299	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Peptidase M16 inactive domain protein
HPMLHGED_02500	0.0	norM	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
HPMLHGED_02501	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_02503	1.37e-60	-	-	-	S	-	-	-	UpxZ family of transcription anti-terminator antagonists
HPMLHGED_02504	1.17e-136	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
HPMLHGED_02505	2.06e-182	-	-	-	L	-	-	-	COG NOG21178 non supervised orthologous group
HPMLHGED_02506	4.4e-27	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02507	1.84e-237	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02508	9.3e-275	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPMLHGED_02509	3.49e-306	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Transporter, major facilitator family protein
HPMLHGED_02510	1.52e-285	galK	2.7.1.6	-	H	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HPMLHGED_02511	8.83e-245	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_02512	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Carbohydrate binding domain protein
HPMLHGED_02513	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_02514	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
HPMLHGED_02515	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02516	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02518	2.24e-180	-	-	-	T	-	-	-	Clostripain family
HPMLHGED_02519	1.94e-86	-	-	-	S	-	-	-	COG NOG31446 non supervised orthologous group
HPMLHGED_02520	6.64e-118	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HPMLHGED_02521	1.27e-189	rpoD	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HPMLHGED_02522	9.2e-122	htrA	-	-	O	-	-	-	Psort location Periplasmic, score
HPMLHGED_02523	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
HPMLHGED_02524	1.11e-142	-	-	-	-	-	-	-	-
HPMLHGED_02525	2.14e-86	-	-	-	-	-	-	-	-
HPMLHGED_02526	1.13e-49	-	-	-	-	-	-	-	-
HPMLHGED_02527	5.38e-24	-	-	-	-	-	-	-	-
HPMLHGED_02529	1.32e-91	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_02530	1.21e-23	-	-	-	NU	-	-	-	TM2 domain containing protein
HPMLHGED_02531	4.52e-28	-	-	-	-	-	-	-	-
HPMLHGED_02533	2.02e-225	-	-	-	S	-	-	-	VirE N-terminal domain
HPMLHGED_02534	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_02535	1.61e-36	-	-	-	-	-	-	-	-
HPMLHGED_02539	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_02540	5.13e-173	-	-	-	O	-	-	-	Glycosyl Hydrolase Family 88
HPMLHGED_02541	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02542	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02543	1.87e-150	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	C-terminal region of aryl-sulfatase
HPMLHGED_02544	5.94e-212	nagZ2	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HPMLHGED_02545	8.8e-314	-	-	-	P	-	-	-	Domain of unknown function (DUF4976)
HPMLHGED_02546	1.57e-195	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
HPMLHGED_02547	3.26e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPMLHGED_02548	1.29e-91	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPMLHGED_02549	2.22e-272	-	-	-	M	-	-	-	Psort location OuterMembrane, score
HPMLHGED_02550	6.89e-236	-	-	-	S	-	-	-	COG NOG26583 non supervised orthologous group
HPMLHGED_02551	9e-279	-	-	-	S	-	-	-	Sulfotransferase family
HPMLHGED_02552	9.81e-231	cysN	2.7.1.25, 2.7.7.4	-	H	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HPMLHGED_02554	0.0	trkA	-	-	C	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems NAD-binding component
HPMLHGED_02555	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPMLHGED_02556	2.35e-243	-	-	-	E	-	-	-	GSCFA family
HPMLHGED_02557	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPMLHGED_02558	2.62e-27	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HPMLHGED_02559	2.69e-189	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HPMLHGED_02560	0.0	-	3.6.4.12	-	L	ko:K10742	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
HPMLHGED_02561	0.0	exuT	-	-	G	ko:K08191	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02563	1.05e-223	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HPMLHGED_02564	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02565	6.41e-306	-	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_02566	3.64e-223	-	3.1.1.11	-	M	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
HPMLHGED_02567	0.0	rhgT_2	3.1.1.11	-	EG	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Extracellular, score
HPMLHGED_02568	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02569	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5123)
HPMLHGED_02570	0.0	-	-	-	J	-	-	-	SusD family
HPMLHGED_02571	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02572	0.0	-	-	-	G	-	-	-	pectate lyase K01728
HPMLHGED_02573	1.09e-151	-	-	-	G	-	-	-	pectate lyase K01728
HPMLHGED_02574	2.12e-200	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02575	0.0	-	-	-	M	-	-	-	F5/8 type C domain
HPMLHGED_02576	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPMLHGED_02577	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02578	0.0	-	-	-	V	-	-	-	COG NOG11095 non supervised orthologous group
HPMLHGED_02579	0.0	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HPMLHGED_02580	2.91e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
HPMLHGED_02581	1.32e-194	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HPMLHGED_02582	0.0	-	-	-	S	-	-	-	PS-10 peptidase S37
HPMLHGED_02583	2.87e-76	-	-	-	K	-	-	-	Transcriptional regulator, MarR
HPMLHGED_02584	0.0	cdr	-	-	P	-	-	-	Belongs to the sulfur carrier protein TusA family
HPMLHGED_02585	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC
HPMLHGED_02586	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_02587	3e-292	-	2.7.1.1	-	G	ko:K00844	ko00010,ko00051,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04910,ko04930,ko04973,ko05230,map00010,map00051,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200,map04066,map04910,map04930,map04973,map05230	ko00000,ko00001,ko00002,ko01000,ko04131	Hexokinase
HPMLHGED_02589	1.02e-65	-	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HPMLHGED_02590	2.37e-20	-	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HPMLHGED_02591	0.0	-	-	-	P	-	-	-	TonB-dependent receptor plug
HPMLHGED_02592	1.92e-106	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HPMLHGED_02593	0.0	rluA	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	Pseudouridine synthase, RluA family
HPMLHGED_02594	4.87e-234	-	-	-	S	-	-	-	Fimbrillin-like
HPMLHGED_02595	3.41e-312	mepA_7	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02596	6.64e-56	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02597	2.13e-68	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02598	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02599	7.88e-166	-	-	-	S	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_02600	4.6e-62	-	-	-	S	-	-	-	COG NOG23408 non supervised orthologous group
HPMLHGED_02601	9.54e-61	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HPMLHGED_02602	0.0	-	-	-	M	ko:K07071	-	ko00000	Domain of unknown function (DUF1731)
HPMLHGED_02603	5.34e-183	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Formamidopyrimidine-DNA glycosylase H2TH domain
HPMLHGED_02604	1.15e-241	mltD_2	-	-	M	-	-	-	Transglycosylase SLT domain protein
HPMLHGED_02605	1.55e-193	-	-	-	J	ko:K10716	-	ko00000,ko02000	Transporter, cation channel family protein
HPMLHGED_02606	3.37e-79	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02607	3.22e-142	mgtC	-	-	S	ko:K07507	-	ko00000,ko02000	Mg2 transporter-C family protein
HPMLHGED_02608	2.23e-189	-	-	-	L	-	-	-	DNA metabolism protein
HPMLHGED_02609	1e-307	-	-	-	S	-	-	-	DNA-binding protein with the Helix-hairpin-helix motif
HPMLHGED_02610	2.42e-118	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_02611	9.72e-183	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPMLHGED_02612	2.06e-46	fjo13	-	-	S	-	-	-	COG NOG19122 non supervised orthologous group
HPMLHGED_02613	2.03e-194	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
HPMLHGED_02614	4.11e-222	-	-	-	H	-	-	-	Methyltransferase domain protein
HPMLHGED_02616	5.91e-46	-	-	-	-	-	-	-	-
HPMLHGED_02617	0.0	-	-	-	M	-	-	-	COG COG3209 Rhs family protein
HPMLHGED_02618	0.0	-	-	-	M	-	-	-	COG3209 Rhs family protein
HPMLHGED_02619	2.84e-10	-	-	-	-	-	-	-	-
HPMLHGED_02620	3.99e-252	-	-	-	-	-	-	-	-
HPMLHGED_02621	1.15e-256	-	-	-	M	ko:K15727	-	ko00000,ko02000	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HPMLHGED_02622	0.0	-	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_02623	9.59e-287	czcC_2	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
HPMLHGED_02624	2.23e-188	-	-	-	M	-	-	-	COG NOG10981 non supervised orthologous group
HPMLHGED_02625	0.0	-	-	-	K	-	-	-	COG NOG18216 non supervised orthologous group
HPMLHGED_02626	4.26e-86	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HPMLHGED_02627	3.39e-293	ydiI	3.1.2.28	-	Q	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02628	2.28e-273	entC	5.4.4.2	-	HQ	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HPMLHGED_02629	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HPMLHGED_02630	6.93e-197	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HPMLHGED_02631	8.36e-259	menC	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02632	2.47e-253	menE	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02633	3e-133	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HPMLHGED_02634	8.64e-220	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_02635	2.98e-170	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02636	6.56e-182	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HPMLHGED_02637	0.0	-	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	Psort location CytoplasmicMembrane, score
HPMLHGED_02638	3.07e-200	-	-	-	M	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HPMLHGED_02639	2.89e-275	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02640	1.56e-112	gmhB	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Polynucleotide kinase 3 phosphatase
HPMLHGED_02641	5.28e-177	gmhB	2.7.7.71	-	JM	ko:K15669	ko00540,map00540	ko00000,ko00001,ko01000	Nucleotidyl transferase
HPMLHGED_02642	6.99e-136	gmhA	5.3.1.28	-	G	ko:K03271	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate
HPMLHGED_02643	2.03e-249	-	2.7.1.168	-	S	ko:K07031	ko00540,map00540	ko00000,ko00001,ko01000	GHMP kinases C terminal
HPMLHGED_02644	3.16e-233	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPMLHGED_02645	2.6e-181	-	-	-	M	-	-	-	Bacterial transferase hexapeptide (six repeats)
HPMLHGED_02646	4.85e-299	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02647	7.9e-312	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HPMLHGED_02648	2.88e-274	-	-	-	-	-	-	-	-
HPMLHGED_02649	1.04e-294	-	-	-	C	-	-	-	coenzyme F420-reducing hydrogenase beta subunit
HPMLHGED_02650	0.0	-	-	-	V	-	-	-	COG NOG25117 non supervised orthologous group
HPMLHGED_02651	6.62e-282	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPMLHGED_02652	6.52e-212	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPMLHGED_02653	4.61e-137	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HPMLHGED_02654	4.23e-213	rfbA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPMLHGED_02655	1.28e-136	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
HPMLHGED_02656	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_02657	0.0	nagZ3	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_02658	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HPMLHGED_02659	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HPMLHGED_02660	0.0	estS	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HPMLHGED_02661	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_02662	6.32e-207	nanH	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat protein
HPMLHGED_02663	1.14e-106	-	-	-	M	-	-	-	PFAM Glycosyl transferases group 1
HPMLHGED_02664	3.13e-182	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HPMLHGED_02666	1.76e-184	-	-	-	S	-	-	-	Erythromycin esterase
HPMLHGED_02668	8.44e-08	-	-	-	M	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HPMLHGED_02669	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02670	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 63 C-terminal domain
HPMLHGED_02671	8.99e-240	madB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	COG COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HPMLHGED_02672	1.18e-171	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HPMLHGED_02673	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HPMLHGED_02674	2.47e-58	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HPMLHGED_02675	6.13e-59	-	-	-	S	-	-	-	COG NOG23407 non supervised orthologous group
HPMLHGED_02676	2.57e-252	-	-	-	G	-	-	-	SMP-30/Gluconolaconase/LRE-like region
HPMLHGED_02677	7.25e-93	-	-	-	-	-	-	-	-
HPMLHGED_02678	1.75e-115	-	-	-	-	-	-	-	-
HPMLHGED_02679	7.36e-100	-	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HPMLHGED_02680	1.67e-288	-	-	-	G	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02681	0.0	hepB	-	-	S	-	-	-	Heparinase II III-like protein
HPMLHGED_02682	2.96e-204	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HPMLHGED_02683	0.0	-	-	-	P	-	-	-	ATP synthase F0, A subunit
HPMLHGED_02684	6.43e-126	-	-	-	-	-	-	-	-
HPMLHGED_02685	4.64e-76	-	-	-	-	-	-	-	-
HPMLHGED_02686	1.19e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_02687	5.36e-36	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
HPMLHGED_02688	0.0	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
HPMLHGED_02689	3.58e-202	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_02690	1.49e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_02691	1.93e-303	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
HPMLHGED_02692	9.67e-104	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_02693	2.76e-99	-	-	-	-	-	-	-	-
HPMLHGED_02694	1.76e-146	-	-	-	S	ko:K03975	-	ko00000	Psort location CytoplasmicMembrane, score
HPMLHGED_02695	7.46e-149	-	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HPMLHGED_02696	3.26e-230	pitA	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HPMLHGED_02697	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HPMLHGED_02698	3.54e-184	-	-	-	O	-	-	-	META domain
HPMLHGED_02699	3.73e-301	-	-	-	-	-	-	-	-
HPMLHGED_02700	2.71e-306	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG1748 Saccharopine dehydrogenase and related
HPMLHGED_02701	7.84e-106	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	bacterioferritin comigratory protein
HPMLHGED_02702	1.46e-240	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPMLHGED_02703	6.32e-228	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02704	6.98e-78	yccF	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02705	2.43e-209	cysL	-	-	K	-	-	-	LysR substrate binding domain protein
HPMLHGED_02706	1.26e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02707	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPMLHGED_02708	6.88e-54	-	-	-	-	-	-	-	-
HPMLHGED_02709	3.12e-95	-	-	-	S	-	-	-	COG NOG14473 non supervised orthologous group
HPMLHGED_02710	2.41e-135	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPMLHGED_02711	1.64e-238	-	-	-	S	-	-	-	COG NOG14472 non supervised orthologous group
HPMLHGED_02712	7.89e-57	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	COG1862 Preprotein translocase subunit YajC
HPMLHGED_02713	8.74e-208	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPMLHGED_02714	9.96e-85	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02715	3.45e-131	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HPMLHGED_02716	6.55e-137	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPMLHGED_02717	3.03e-91	hslR	-	-	J	ko:K04762	-	ko00000,ko03110	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HPMLHGED_02718	1.14e-100	-	-	-	FG	-	-	-	Histidine triad domain protein
HPMLHGED_02719	0.0	nhaA	-	-	P	ko:K03455	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02720	1.72e-268	gcvT	2.1.2.10	-	H	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HPMLHGED_02721	4.83e-296	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HPMLHGED_02722	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine phosphoribosylpyrophosphate amidotransferase
HPMLHGED_02723	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HPMLHGED_02724	5.63e-255	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HPMLHGED_02725	3.04e-124	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02726	5.45e-231	arnC	-	-	M	-	-	-	involved in cell wall biogenesis
HPMLHGED_02727	4.39e-171	-	-	-	S	-	-	-	COG NOG28307 non supervised orthologous group
HPMLHGED_02728	7.56e-129	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HPMLHGED_02729	3.63e-247	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPMLHGED_02730	8.85e-85	-	-	-	S	ko:K09922	-	ko00000	Psort location CytoplasmicMembrane, score
HPMLHGED_02731	6.12e-178	ttcA	-	-	H	ko:K14058	-	ko00000,ko03016	Belongs to the TtcA family
HPMLHGED_02732	6.5e-262	dapE	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02733	1.4e-261	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPMLHGED_02734	4.47e-109	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
HPMLHGED_02735	1.64e-193	-	-	-	S	-	-	-	COG NOG19137 non supervised orthologous group
HPMLHGED_02736	1.41e-267	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_02737	4.18e-299	-	-	-	S	-	-	-	Belongs to the UPF0597 family
HPMLHGED_02738	4.57e-129	slyD	5.2.1.8	-	G	ko:K03775	-	ko00000,ko01000,ko03110	Psort location Cytoplasmic, score
HPMLHGED_02739	2.1e-276	-	-	-	G	ko:K02429	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02740	0.0	-	3.2.1.21	GH3	M	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Fibronectin type III-like domain
HPMLHGED_02741	1.76e-87	celC	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Cellulase (glycosyl hydrolase family 5)
HPMLHGED_02742	7.85e-07	-	-	-	E	-	-	-	Domain of unknown function (DUF5018)
HPMLHGED_02743	1.63e-213	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_02744	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_02746	1.96e-214	-	-	-	Q	-	-	-	Dienelactone hydrolase
HPMLHGED_02747	6.19e-263	-	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional regulator (AraC family)
HPMLHGED_02748	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HPMLHGED_02749	2.43e-131	-	5.2.1.8	-	M	ko:K01802,ko:K03773	-	ko00000,ko01000,ko03110	FkbP-type peptidyl-prolyl cis-trans
HPMLHGED_02750	1.48e-246	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.97
HPMLHGED_02751	2.21e-227	fdh	1.1.1.122	-	C	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Oxidoreductase, aldo keto reductase family protein
HPMLHGED_02752	1.68e-225	-	-	-	S	ko:K07045	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02753	6.44e-302	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
HPMLHGED_02754	9.17e-241	yjmD_1	-	-	E	-	-	-	Psort location Cytoplasmic, score 9.97
HPMLHGED_02755	2.73e-203	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02756	1.17e-267	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02757	8.04e-292	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02758	0.0	lytB	-	-	D	ko:K06381	-	ko00000	SpoIID LytB domain protein
HPMLHGED_02759	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_02760	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPMLHGED_02761	9.74e-294	-	-	-	S	-	-	-	Lamin Tail Domain
HPMLHGED_02762	3.65e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF4857)
HPMLHGED_02763	2.8e-152	-	-	-	-	-	-	-	-
HPMLHGED_02764	4.59e-217	-	-	-	V	ko:K01990,ko:K19340	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
HPMLHGED_02765	9.29e-132	-	-	-	S	ko:K09939	-	ko00000	Putative PepSY_TM-like
HPMLHGED_02766	9.06e-122	-	-	-	-	-	-	-	-
HPMLHGED_02767	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
HPMLHGED_02768	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02769	1.3e-302	-	-	-	S	-	-	-	Protein of unknown function (DUF4876)
HPMLHGED_02770	0.0	-	-	-	P	-	-	-	COG NOG11715 non supervised orthologous group
HPMLHGED_02771	3.45e-239	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPMLHGED_02772	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HPMLHGED_02773	8.72e-142	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HPMLHGED_02774	1.08e-242	pdxB	1.1.1.290	-	H	ko:K03473	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
HPMLHGED_02775	1.85e-142	-	-	-	M	-	-	-	Protein of unknown function (DUF4254)
HPMLHGED_02776	5.83e-251	-	-	GT9	M	ko:K02843	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyltransferase family 9
HPMLHGED_02777	4.25e-230	lpsA	-	-	S	-	-	-	Glycosyl transferase family 90
HPMLHGED_02778	1.14e-183	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02779	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_02780	1.26e-246	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_02781	1.68e-279	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02782	3.14e-281	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02783	4.17e-300	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02784	2.07e-237	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_02785	6.93e-236	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_02786	7.56e-243	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family
HPMLHGED_02787	5.35e-102	-	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	acetyltransferase
HPMLHGED_02788	9.94e-287	-	-	-	F	-	-	-	ATP-grasp domain
HPMLHGED_02789	1.06e-277	-	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase class-V
HPMLHGED_02790	2.46e-272	vioA	2.6.1.33	-	E	ko:K20429	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HPMLHGED_02791	8.63e-15	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
HPMLHGED_02792	1.67e-201	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
HPMLHGED_02793	9.46e-77	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02794	2.2e-223	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HPMLHGED_02795	1.02e-297	-	-	-	-	-	-	-	-
HPMLHGED_02796	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02797	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02798	7.85e-145	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02799	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_02800	0.0	msbA	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HPMLHGED_02801	2.52e-193	-	-	-	G	-	-	-	Domain of unknown function (DUF3473)
HPMLHGED_02802	0.0	-	-	-	S	-	-	-	Pfam:DUF2029
HPMLHGED_02803	1.21e-267	-	-	-	S	-	-	-	Pfam:DUF2029
HPMLHGED_02804	4.28e-97	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02805	5.87e-165	rnhA	3.1.26.4	-	C	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	double-stranded RNA RNA-DNA hybrid binding protein
HPMLHGED_02806	1.31e-146	-	-	-	S	ko:K07078	-	ko00000	oxidoreductase related to nitroreductase
HPMLHGED_02807	2.82e-122	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HPMLHGED_02808	0.0	speA	4.1.1.19	-	H	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the biosynthesis of agmatine from arginine
HPMLHGED_02809	1.69e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HPMLHGED_02810	5.95e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_02811	6.08e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02812	1.19e-131	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HPMLHGED_02813	3.15e-163	-	-	-	S	ko:K07043	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02814	1.13e-84	-	-	-	S	-	-	-	COG NOG29451 non supervised orthologous group
HPMLHGED_02815	1.04e-207	-	-	-	S	ko:K07126	-	ko00000	beta-lactamase activity
HPMLHGED_02816	2.5e-104	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HPMLHGED_02817	1.02e-295	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HPMLHGED_02818	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPMLHGED_02819	2.98e-55	cvpA	-	-	S	ko:K03558	-	ko00000	Psort location CytoplasmicMembrane, score
HPMLHGED_02820	0.0	sufB	-	-	O	ko:K09014	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
HPMLHGED_02821	2.3e-174	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component
HPMLHGED_02822	0.0	sufD	-	-	O	ko:K09015	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
HPMLHGED_02823	2.28e-292	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
HPMLHGED_02824	1.3e-65	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HPMLHGED_02825	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HPMLHGED_02826	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_02827	0.0	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HPMLHGED_02828	3.58e-96	dapH	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HPMLHGED_02829	4.9e-305	waaA	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Psort location Cytoplasmic, score 8.96
HPMLHGED_02830	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPMLHGED_02831	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HPMLHGED_02832	1.33e-99	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HPMLHGED_02833	1.94e-100	-	-	-	U	ko:K03559	-	ko00000,ko02000	Biopolymer transport protein ExbD/TolR
HPMLHGED_02834	0.0	-	-	-	U	ko:K03561	-	ko00000,ko02000	MotA/TolQ/ExbB proton channel family
HPMLHGED_02836	4.43e-33	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
HPMLHGED_02837	3.98e-314	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_02838	5.71e-152	-	-	-	L	-	-	-	regulation of translation
HPMLHGED_02839	0.0	-	-	-	S	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HPMLHGED_02840	0.0	-	-	-	S	-	-	-	N-terminal domain of M60-like peptidases
HPMLHGED_02841	0.0	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_02842	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF5124)
HPMLHGED_02843	4.01e-179	-	-	-	S	-	-	-	Fasciclin domain
HPMLHGED_02844	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02845	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_02846	5.47e-243	-	-	-	S	-	-	-	Domain of unknown function (DUF5007)
HPMLHGED_02847	2.32e-190	-	-	-	M	-	-	-	COG2335, Secreted and surface protein containing fasciclin-like repeats
HPMLHGED_02848	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_02850	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_02851	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HPMLHGED_02852	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02853	0.0	-	-	-	G	-	-	-	Ricin-type beta-trefoil lectin domain-like
HPMLHGED_02854	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_02855	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02856	2.48e-57	-	-	-	S	-	-	-	COG NOG23371 non supervised orthologous group
HPMLHGED_02857	4.29e-135	-	-	-	I	-	-	-	Acyltransferase
HPMLHGED_02858	1.11e-191	ramA_1	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
HPMLHGED_02859	0.0	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02860	0.0	xly	-	-	M	-	-	-	fibronectin type III domain protein
HPMLHGED_02861	5.77e-68	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02862	4.08e-47	-	-	-	O	-	-	-	Belongs to the sulfur carrier protein TusA family
HPMLHGED_02863	3.45e-106	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02864	6.23e-171	wcgX	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_02865	9.22e-181	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_02866	1.17e-36	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HPMLHGED_02867	6.21e-265	-	-	-	S	-	-	-	VWA domain containing CoxE-like protein
HPMLHGED_02868	0.0	-	-	-	-	-	-	-	-
HPMLHGED_02869	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	COG0058 Glucan phosphorylase
HPMLHGED_02870	2.51e-259	-	-	-	O	-	-	-	Antioxidant, AhpC TSA family
HPMLHGED_02871	0.0	potA	3.6.3.31	-	P	ko:K10112,ko:K11072,ko:K17324	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HPMLHGED_02872	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPMLHGED_02873	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02874	3.78e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_02875	1.08e-129	-	-	-	S	-	-	-	PFAM NLP P60 protein
HPMLHGED_02876	5.63e-222	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_02877	1.11e-113	-	-	-	S	-	-	-	GDYXXLXY protein
HPMLHGED_02878	5.19e-205	-	-	-	S	-	-	-	Domain of unknown function (DUF4401)
HPMLHGED_02879	1.87e-210	-	-	-	S	-	-	-	Predicted membrane protein (DUF2157)
HPMLHGED_02880	2.86e-314	poxB	1.2.5.1, 2.2.1.6	-	C	ko:K00156,ko:K01652	ko00290,ko00620,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HPMLHGED_02881	5.92e-81	-	-	-	-	-	-	-	-
HPMLHGED_02882	3.35e-247	-	-	-	S	-	-	-	Oxidoreductase, NAD-binding domain protein
HPMLHGED_02883	4.15e-108	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
HPMLHGED_02884	5.43e-186	-	-	-	-	-	-	-	-
HPMLHGED_02885	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
HPMLHGED_02886	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
HPMLHGED_02887	7.64e-247	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02888	4.33e-192	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HPMLHGED_02889	3.33e-66	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
HPMLHGED_02890	3.68e-173	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HPMLHGED_02891	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase, glutamine-hydrolyzing
HPMLHGED_02892	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related
HPMLHGED_02893	2.54e-74	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	GXGXG motif
HPMLHGED_02894	1.8e-295	-	-	-	G	-	-	-	beta-galactosidase
HPMLHGED_02895	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_02896	2.81e-176	-	4.2.2.23	PL11	S	ko:K18197	-	ko00000,ko01000	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238
HPMLHGED_02897	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_02898	2.83e-236	-	-	-	G	-	-	-	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HPMLHGED_02899	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_02900	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
HPMLHGED_02902	2.41e-201	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Ser Thr phosphatase family protein
HPMLHGED_02903	5.43e-183	ushA	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HPMLHGED_02904	3.06e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPMLHGED_02905	8.01e-229	glk	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
HPMLHGED_02906	9.38e-168	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_02907	8.48e-303	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HPMLHGED_02908	3.15e-295	macB_3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HPMLHGED_02909	7.55e-245	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_02910	9.59e-304	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Psort location OuterMembrane, score 10.00
HPMLHGED_02911	2.2e-250	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HPMLHGED_02912	1.25e-119	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
HPMLHGED_02913	0.0	pbpF	-	-	M	-	-	-	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HPMLHGED_02914	2.95e-138	-	-	-	S	-	-	-	COG NOG36047 non supervised orthologous group
HPMLHGED_02915	4.17e-237	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
HPMLHGED_02916	6.64e-162	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
HPMLHGED_02917	6.57e-165	yitL	-	-	S	ko:K00243	-	ko00000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02918	2.75e-69	-	-	-	-	-	-	-	-
HPMLHGED_02919	3.28e-280	-	-	-	K	ko:K13652	-	ko00000,ko03000	Bacterial transcription activator, effector binding domain
HPMLHGED_02920	2.41e-164	-	-	-	C	-	-	-	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HPMLHGED_02921	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02922	0.0	-	-	-	G	-	-	-	IPT/TIG domain
HPMLHGED_02923	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases
HPMLHGED_02924	5.37e-255	-	-	-	G	-	-	-	Glycosyl hydrolase
HPMLHGED_02925	0.0	-	-	-	T	-	-	-	Response regulator receiver domain protein
HPMLHGED_02926	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HPMLHGED_02928	1.56e-257	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HPMLHGED_02929	7.39e-225	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG COG0524 Sugar kinases, ribokinase family
HPMLHGED_02930	9.89e-138	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	sugar phosphate isomerase involved in capsule formation
HPMLHGED_02931	4.92e-109	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HPMLHGED_02932	9.01e-296	-	-	-	S	-	-	-	Belongs to the peptidase M16 family
HPMLHGED_02933	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02934	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02935	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_02936	1.32e-130	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_02937	1.39e-286	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_02938	2.78e-294	-	-	-	NU	-	-	-	bacterial-type flagellum-dependent cell motility
HPMLHGED_02939	0.0	acsA	6.2.1.1, 6.2.1.32	-	I	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
HPMLHGED_02940	6.02e-129	-	-	-	K	-	-	-	KOW (Kyprides, Ouzounis, Woese) motif.
HPMLHGED_02941	0.0	-	-	-	O	-	-	-	COG COG0457 FOG TPR repeat
HPMLHGED_02942	1.82e-174	trmH	2.1.1.185	-	J	ko:K03218,ko:K03437	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPMLHGED_02943	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HPMLHGED_02944	3.05e-213	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPMLHGED_02945	4.84e-106	-	-	-	C	ko:K02121	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG NOG11642 non supervised orthologous group
HPMLHGED_02946	6.12e-194	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02947	2.55e-229	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HPMLHGED_02948	8.82e-170	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HPMLHGED_02949	1.09e-162	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
HPMLHGED_02950	2.22e-83	-	-	-	U	ko:K03559	-	ko00000,ko02000	Transport energizing protein, ExbD TolR family
HPMLHGED_02951	4.82e-158	-	-	-	M	-	-	-	TonB family domain protein
HPMLHGED_02952	1.18e-127	yajL	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HPMLHGED_02953	6.64e-154	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HPMLHGED_02954	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HPMLHGED_02955	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HPMLHGED_02956	8.25e-131	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HPMLHGED_02957	7.77e-58	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HPMLHGED_02958	1.48e-99	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPMLHGED_02959	8.31e-159	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPMLHGED_02960	4.02e-116	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L10
HPMLHGED_02961	3.16e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPMLHGED_02962	5.36e-108	-	-	-	DM	-	-	-	Chain length determinant protein
HPMLHGED_02963	3.11e-08	-	-	-	S	-	-	-	ATPase (AAA
HPMLHGED_02964	0.0	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
HPMLHGED_02966	1.37e-313	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_02967	4.82e-88	-	-	-	L	-	-	-	COG NOG29624 non supervised orthologous group
HPMLHGED_02968	5.68e-128	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_02969	0.0	-	-	-	S	-	-	-	COG NOG22466 non supervised orthologous group
HPMLHGED_02972	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_02973	1.03e-302	-	-	-	-	-	-	-	-
HPMLHGED_02974	1.07e-266	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin
HPMLHGED_02975	2.69e-186	-	-	-	S	ko:K02651	ko04112,map04112	ko00000,ko00001,ko02035,ko02044	COG NOG28004 non supervised orthologous group
HPMLHGED_02976	1.11e-237	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	COG COG0147 Anthranilate para-aminobenzoate synthases component I
HPMLHGED_02977	4.06e-140	-	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_02978	8.44e-168	-	-	-	S	-	-	-	TIGR02453 family
HPMLHGED_02979	9.59e-101	tabA_2	-	-	G	-	-	-	YhcH YjgK YiaL family protein
HPMLHGED_02980	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	1,4-alpha-glucan branching enzyme
HPMLHGED_02981	1.5e-111	-	-	-	S	-	-	-	COG NOG29454 non supervised orthologous group
HPMLHGED_02982	0.0	amyA2	-	-	G	-	-	-	Alpha amylase, catalytic domain
HPMLHGED_02983	7.22e-196	-	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HPMLHGED_02984	6.14e-99	yccM_2	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_02985	4.87e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_02986	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_02987	0.0	-	-	-	S	-	-	-	non supervised orthologous group
HPMLHGED_02988	9.5e-289	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HPMLHGED_02989	9.19e-287	-	-	-	N	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_02990	1.09e-208	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_02991	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HPMLHGED_02992	1.3e-236	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_02993	1.65e-141	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, Bacteroides expansion family 1
HPMLHGED_02994	0.0	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
HPMLHGED_02995	2.58e-155	pflA_1	1.97.1.4	-	O	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HPMLHGED_02996	2.93e-145	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
HPMLHGED_02997	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase I and helicase II
HPMLHGED_02998	2.93e-259	pleD	2.7.13.3	-	T	ko:K11527	-	ko00000,ko01000,ko01001,ko02022	Response regulator receiver domain protein
HPMLHGED_02999	2.22e-231	-	4.1.1.35	-	GM	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
HPMLHGED_03000	7.15e-228	-	-	-	-	-	-	-	-
HPMLHGED_03001	1.28e-226	-	-	-	-	-	-	-	-
HPMLHGED_03002	1.76e-232	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HPMLHGED_03003	0.0	-	-	-	S	-	-	-	COG NOG34047 non supervised orthologous group
HPMLHGED_03004	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HPMLHGED_03005	1.05e-142	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HPMLHGED_03006	0.0	-	-	-	-	-	-	-	-
HPMLHGED_03007	1.61e-185	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03008	6.95e-282	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
HPMLHGED_03009	8.87e-316	cfiA	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
HPMLHGED_03010	5.93e-293	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	COG COG3669 Alpha-L-fucosidase
HPMLHGED_03011	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_03012	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03013	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HPMLHGED_03014	3.34e-307	-	-	-	S	-	-	-	Domain of unknown function (DUF5126)
HPMLHGED_03015	4.18e-24	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_03016	0.0	-	4.2.2.5	PL8	N	ko:K19049	-	ko00000,ko01000	Polysaccharide lyase family 8, super-sandwich domain
HPMLHGED_03017	0.0	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_03018	7.05e-216	-	-	-	E	-	-	-	COG NOG17363 non supervised orthologous group
HPMLHGED_03019	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03020	7.28e-93	-	-	-	S	-	-	-	amine dehydrogenase activity
HPMLHGED_03022	1.31e-114	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03023	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HPMLHGED_03024	5.28e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_03025	3.73e-25	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HPMLHGED_03026	1.62e-171	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HPMLHGED_03027	1.61e-62	-	-	-	L	-	-	-	Arm DNA-binding domain
HPMLHGED_03028	1.36e-141	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HPMLHGED_03029	1.11e-131	-	-	-	EG	-	-	-	EamA-like transporter family
HPMLHGED_03030	1.44e-78	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HPMLHGED_03032	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HPMLHGED_03033	1.19e-310	mepA_6	-	-	V	-	-	-	MATE efflux family protein
HPMLHGED_03034	2.87e-100	-	-	-	K	-	-	-	Protein of unknown function (DUF3788)
HPMLHGED_03035	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
HPMLHGED_03036	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3858)
HPMLHGED_03037	7.45e-111	-	-	-	K	-	-	-	acetyltransferase
HPMLHGED_03038	2.13e-142	-	-	-	O	-	-	-	Heat shock protein
HPMLHGED_03039	4.8e-115	-	-	-	K	-	-	-	LytTr DNA-binding domain
HPMLHGED_03040	5.21e-167	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_03041	1.42e-187	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_03042	0.0	-	-	-	V	ko:K03296	-	ko00000	AcrB/AcrD/AcrF family
HPMLHGED_03043	2e-224	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor
HPMLHGED_03044	1.42e-47	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HPMLHGED_03045	1.77e-283	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03046	2.47e-131	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain protein
HPMLHGED_03047	1.81e-234	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_03048	3.51e-223	nhaS3	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HPMLHGED_03049	5.74e-204	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03050	0.0	-	-	-	K	-	-	-	Transcriptional regulator
HPMLHGED_03051	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03052	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03053	1.76e-199	ddpX	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HPMLHGED_03054	1.52e-83	-	-	-	-	-	-	-	-
HPMLHGED_03055	2.55e-23	-	-	-	M	-	-	-	TIGRFAM RHS repeat-associated core domain
HPMLHGED_03056	7.84e-264	-	-	-	S	ko:K03646	-	ko00000,ko02000	Domain of unknown function (DUF4468) with TBP-like fold
HPMLHGED_03057	9.11e-182	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03058	7.53e-157	pdxH	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HPMLHGED_03059	5.26e-172	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
HPMLHGED_03060	6.95e-238	ldhA	1.1.1.28	-	C	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPMLHGED_03061	0.0	-	-	-	I	ko:K06076	-	ko00000,ko02000	COG COG2067 Long-chain fatty acid transport protein
HPMLHGED_03062	0.0	-	-	-	S	-	-	-	COG NOG10142 non supervised orthologous group
HPMLHGED_03063	1.59e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03064	6.46e-83	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2141)
HPMLHGED_03065	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HPMLHGED_03066	9.64e-35	-	-	-	K	-	-	-	Putative ATP-dependent DNA helicase recG C-terminal
HPMLHGED_03067	9.51e-239	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPMLHGED_03068	9.79e-232	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03069	2.11e-249	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
HPMLHGED_03070	1.82e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HPMLHGED_03071	4.81e-231	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_03072	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03073	9.38e-232	-	-	-	G	ko:K21572	-	ko00000,ko02000	Starch-binding associating with outer membrane
HPMLHGED_03074	1.3e-114	-	-	-	S	-	-	-	Putative zinc-binding metallo-peptidase
HPMLHGED_03075	1.55e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4302)
HPMLHGED_03077	0.0	rnr	-	-	J	ko:K12573,ko:K12585	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HPMLHGED_03078	2.21e-109	-	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase family protein
HPMLHGED_03079	8.37e-53	-	-	-	K	-	-	-	Sigma-70, region 4
HPMLHGED_03080	4.64e-78	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_03081	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_03082	7.76e-255	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_03083	1.1e-60	-	-	-	N	-	-	-	Protein of unknown function (DUF3823)
HPMLHGED_03084	6.19e-151	-	-	-	M	-	-	-	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
HPMLHGED_03085	6.22e-216	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HPMLHGED_03086	9.2e-80	-	-	-	S	-	-	-	Cupin domain protein
HPMLHGED_03087	7.38e-116	-	3.2.1.80	-	M	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
HPMLHGED_03088	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_03089	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HPMLHGED_03090	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Periplasmic, score
HPMLHGED_03092	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03093	1.41e-154	-	-	-	M	-	-	-	COG NOG27406 non supervised orthologous group
HPMLHGED_03094	0.0	nagA	-	-	G	-	-	-	b-glycosidase, glycoside hydrolase family 3 protein
HPMLHGED_03095	1.13e-217	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Ser Thr phosphatase family protein
HPMLHGED_03096	5.97e-188	ushA	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HPMLHGED_03097	1.11e-261	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_03098	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HPMLHGED_03099	2.09e-209	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_03100	9.82e-261	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_03101	0.0	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_03102	2.2e-225	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_03103	5.68e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPMLHGED_03104	4.75e-132	-	-	-	-	-	-	-	-
HPMLHGED_03105	2.39e-108	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_03106	1.67e-115	glk	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
HPMLHGED_03107	0.0	-	-	-	S	-	-	-	Putative binding domain, N-terminal
HPMLHGED_03108	0.0	-	-	-	S	-	-	-	leucine rich repeat protein
HPMLHGED_03109	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5003)
HPMLHGED_03110	8.54e-215	-	-	-	S	-	-	-	Domain of unknown function (DUF4984)
HPMLHGED_03111	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Starch-binding associating with outer membrane
HPMLHGED_03112	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03114	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPMLHGED_03115	3.85e-117	-	-	-	T	-	-	-	Tyrosine phosphatase family
HPMLHGED_03116	3.03e-280	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis bifunctional protein HisB
HPMLHGED_03117	2.3e-254	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPMLHGED_03118	1.69e-295	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPMLHGED_03119	1.62e-195	hisG	2.4.2.17	-	F	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HPMLHGED_03120	5.38e-121	-	-	-	Q	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03121	0.0	-	-	-	S	-	-	-	Fibrobacter succinogenes major domain (Fib_succ_major)
HPMLHGED_03122	2.08e-145	-	-	-	S	-	-	-	Protein of unknown function (DUF2490)
HPMLHGED_03123	0.0	-	-	-	G	ko:K07783	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03124	2.28e-219	glpQ1_1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03125	8.15e-267	-	-	-	S	-	-	-	Beta-lactamase superfamily domain
HPMLHGED_03126	4.59e-216	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03127	0.0	-	-	-	S	-	-	-	Fibronectin type III domain
HPMLHGED_03128	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_03129	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03130	1.01e-225	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_03131	5.09e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_03132	1.4e-176	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
HPMLHGED_03133	0.0	dsbD	1.8.1.8	-	CO	ko:K04084	-	ko00000,ko01000,ko03110	cytochrome c biogenesis protein transmembrane region
HPMLHGED_03134	2.43e-64	-	-	-	S	-	-	-	Stress responsive A B barrel domain protein
HPMLHGED_03135	3.19e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03136	0.0	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
HPMLHGED_03137	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPMLHGED_03138	2.44e-25	-	-	-	-	-	-	-	-
HPMLHGED_03139	1.08e-140	-	-	-	C	-	-	-	COG0778 Nitroreductase
HPMLHGED_03140	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03141	7.84e-101	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPMLHGED_03142	3.81e-123	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03143	3.38e-182	-	-	-	S	-	-	-	COG NOG34011 non supervised orthologous group
HPMLHGED_03144	1.44e-113	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03145	1.79e-96	-	-	-	-	-	-	-	-
HPMLHGED_03146	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
HPMLHGED_03147	1.15e-152	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HPMLHGED_03148	3.56e-188	bioC	2.1.1.197, 3.1.1.85	-	H	ko:K02169,ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
HPMLHGED_03149	1.51e-159	-	3.1.1.85	-	S	ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Protein of unknown function (DUF452)
HPMLHGED_03150	1.23e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	COG COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
HPMLHGED_03151	0.0	bioA	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a
HPMLHGED_03152	6.01e-269	-	-	-	N	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03153	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03154	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	COG NOG25454 non supervised orthologous group
HPMLHGED_03155	4.43e-270	fsr	-	-	G	ko:K08223	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03156	5.76e-266	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HPMLHGED_03157	1.3e-26	-	-	-	S	-	-	-	Transglycosylase associated protein
HPMLHGED_03158	5.01e-44	-	-	-	-	-	-	-	-
HPMLHGED_03159	5.67e-245	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
HPMLHGED_03160	3.54e-188	uxuB	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HPMLHGED_03161	6.72e-287	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HPMLHGED_03162	5.46e-136	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
HPMLHGED_03163	2.94e-197	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03164	1.02e-97	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase like
HPMLHGED_03165	4.22e-59	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HPMLHGED_03167	1.98e-194	-	-	-	S	-	-	-	RteC protein
HPMLHGED_03168	9.41e-113	-	-	-	S	-	-	-	Protein of unknown function (DUF1062)
HPMLHGED_03170	3.61e-158	-	-	-	S	ko:K09807	-	ko00000	Protein of unknown function (DUF541)
HPMLHGED_03171	9.06e-136	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03172	2.33e-19	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HPMLHGED_03173	2.38e-78	-	-	-	-	-	-	-	-
HPMLHGED_03174	2.36e-71	-	-	-	-	-	-	-	-
HPMLHGED_03175	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
HPMLHGED_03176	1.48e-114	-	-	-	S	-	-	-	Domain of unknown function (DUF4625)
HPMLHGED_03177	1.66e-148	nrfH	-	-	C	ko:K15876	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002	COG COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit
HPMLHGED_03178	0.0	nrfA	1.7.2.2	-	C	ko:K03385	ko00910,ko01120,ko05132,map00910,map01120,map05132	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
HPMLHGED_03179	1.01e-290	ccs1	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03182	1.08e-89	-	-	-	-	-	-	-	-
HPMLHGED_03184	0.0	-	-	-	S	-	-	-	TROVE domain
HPMLHGED_03185	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HPMLHGED_03186	5.83e-222	lacX	-	-	G	-	-	-	COG COG2017 Galactose mutarotase and related enzymes
HPMLHGED_03187	1.12e-73	-	-	-	S	ko:K21571	-	ko00000	Domain of unknown function (DUF5114)
HPMLHGED_03188	6.74e-271	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan endo-1,4-beta-galactosidase
HPMLHGED_03189	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_03190	1.01e-157	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03191	0.0	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03192	0.0	trpB	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPMLHGED_03193	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03194	0.0	-	4.2.2.8	PL12	M	ko:K19052	-	ko00000,ko01000	Heparinase II III-like protein
HPMLHGED_03195	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4958)
HPMLHGED_03196	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03197	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_03198	0.0	-	-	-	S	-	-	-	Glycosyl Hydrolase Family 88
HPMLHGED_03199	0.0	-	4.2.2.8	PL12	M	ko:K19052	-	ko00000,ko01000	Heparinase II III-like protein
HPMLHGED_03200	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_03201	0.0	-	-	-	S	-	-	-	PHP domain protein
HPMLHGED_03202	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPMLHGED_03203	1.74e-88	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
HPMLHGED_03204	1.13e-174	-	-	-	T	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
HPMLHGED_03205	0.0	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_03206	6.78e-217	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
HPMLHGED_03207	1.01e-286	rlmL	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HPMLHGED_03208	0.0	-	-	-	C	-	-	-	Domain of unknown function (DUF4132)
HPMLHGED_03209	4.15e-108	msrC	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03210	3.55e-69	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03211	3.96e-183	dnaJ2	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	Psort location Cytoplasmic, score
HPMLHGED_03212	2.35e-164	-	-	-	H	-	-	-	Methyltransferase domain
HPMLHGED_03213	8.45e-140	-	-	-	M	-	-	-	Chaperone of endosialidase
HPMLHGED_03216	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_03217	4.32e-167	-	-	-	L	-	-	-	AAA domain
HPMLHGED_03218	2.46e-132	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPMLHGED_03219	1.69e-120	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HPMLHGED_03220	0.0	-	-	-	P	ko:K03305	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03221	2.87e-47	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HPMLHGED_03224	0.0	-	-	-	O	-	-	-	Psort location Extracellular, score
HPMLHGED_03225	1.29e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HPMLHGED_03226	6.6e-115	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03227	3.67e-102	fur	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HPMLHGED_03228	2.58e-137	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03229	1.13e-134	-	-	-	C	-	-	-	Nitroreductase family
HPMLHGED_03230	2.41e-106	-	-	-	O	-	-	-	Thioredoxin
HPMLHGED_03231	5.28e-68	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Psort location Cytoplasmic, score
HPMLHGED_03232	5.36e-270	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03233	3.69e-37	-	-	-	-	-	-	-	-
HPMLHGED_03234	0.0	-	-	-	S	-	-	-	COG NOG06390 non supervised orthologous group
HPMLHGED_03235	0.0	dpp11	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
HPMLHGED_03236	0.0	atsB	-	-	C	ko:K06871	-	ko00000	COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
HPMLHGED_03237	6.32e-169	-	-	-	S	-	-	-	COG NOG27017 non supervised orthologous group
HPMLHGED_03238	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_03239	4.44e-72	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
HPMLHGED_03240	3.02e-111	-	-	-	CG	-	-	-	glycosyl
HPMLHGED_03241	9.9e-202	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HPMLHGED_03242	3.27e-294	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HPMLHGED_03243	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HPMLHGED_03244	7.78e-281	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
HPMLHGED_03245	2.25e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03246	9.17e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03247	3.97e-38	metH_2	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain
HPMLHGED_03248	1.66e-56	hupA	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HPMLHGED_03249	0.0	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	S1 RNA binding domain
HPMLHGED_03250	7.38e-234	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_03251	8.73e-127	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HPMLHGED_03252	2.95e-216	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_03253	1.2e-167	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03254	7.21e-242	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_03256	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HPMLHGED_03257	2.65e-62	-	-	-	P	ko:K14445	-	ko00000,ko02000	Citrate transporter
HPMLHGED_03258	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03260	8.52e-60	-	-	-	-	-	-	-	-
HPMLHGED_03262	2.84e-18	-	-	-	-	-	-	-	-
HPMLHGED_03263	9.13e-37	-	-	-	-	-	-	-	-
HPMLHGED_03264	2.61e-300	-	-	-	E	-	-	-	FAD dependent oxidoreductase
HPMLHGED_03267	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
HPMLHGED_03268	1.52e-89	-	-	-	S	-	-	-	Polyketide cyclase / dehydrase and lipid transport
HPMLHGED_03269	4.36e-103	pyrE	2.4.2.10, 4.1.1.23	-	F	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPMLHGED_03270	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HPMLHGED_03273	2.58e-52	-	-	-	F	ko:K21572	-	ko00000,ko02000	PFAM SusD family
HPMLHGED_03274	6.78e-33	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HPMLHGED_03275	4e-180	-	-	-	GM	-	-	-	Parallel beta-helix repeats
HPMLHGED_03276	4.38e-175	-	-	-	GM	-	-	-	Parallel beta-helix repeats
HPMLHGED_03277	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HPMLHGED_03278	2.84e-197	-	2.4.1.339, 2.4.1.340	GH130	G	ko:K20885	-	ko00000,ko01000	Pfam:DUF377
HPMLHGED_03279	1.97e-143	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPMLHGED_03280	4.98e-237	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPMLHGED_03281	3.3e-126	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMLHGED_03282	6.92e-106	nodN	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03283	2.11e-148	-	-	-	U	ko:K05595	-	ko00000,ko02000	MarC family integral membrane protein
HPMLHGED_03284	1.5e-124	-	-	-	S	-	-	-	COG NOG35345 non supervised orthologous group
HPMLHGED_03285	0.0	gloA	4.4.1.5	-	E	ko:K01759,ko:K03827	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03286	1.79e-213	per1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	COG2367 Beta-lactamase class A
HPMLHGED_03288	1.22e-133	-	-	-	K	-	-	-	transcriptional regulator (AraC
HPMLHGED_03289	3.24e-290	-	-	-	S	-	-	-	SEC-C motif
HPMLHGED_03290	1.79e-79	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_03291	1.3e-117	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HPMLHGED_03292	7.01e-213	-	-	-	S	-	-	-	HEPN domain
HPMLHGED_03293	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_03294	7.67e-105	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
HPMLHGED_03295	4.99e-273	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03296	1.59e-121	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03297	0.0	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03298	3.35e-167	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03299	2.86e-28	-	-	-	S	-	-	-	SWIM zinc finger
HPMLHGED_03300	7.3e-77	-	-	-	S	-	-	-	SWIM zinc finger
HPMLHGED_03301	9.25e-230	-	-	-	L	-	-	-	Winged helix-turn helix
HPMLHGED_03302	4.07e-49	-	-	-	-	-	-	-	-
HPMLHGED_03303	9.52e-129	-	-	-	-	-	-	-	-
HPMLHGED_03304	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HPMLHGED_03305	0.0	-	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HPMLHGED_03307	2.05e-117	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
HPMLHGED_03308	3.9e-35	-	-	-	S	-	-	-	COG NOG19145 non supervised orthologous group
HPMLHGED_03309	4.25e-114	-	-	-	L	-	-	-	restriction endonuclease
HPMLHGED_03310	5.01e-80	-	-	-	-	-	-	-	-
HPMLHGED_03311	2.22e-146	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03313	1.27e-146	mrcB	2.4.1.129, 3.4.16.4	GT51	M	ko:K05365,ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HPMLHGED_03314	3.29e-143	-	-	-	-	-	-	-	-
HPMLHGED_03315	9.29e-109	-	-	-	-	-	-	-	-
HPMLHGED_03316	9.72e-313	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_03317	1.15e-82	-	-	-	L	ko:K07483	-	ko00000	COG2963 Transposase and inactivated derivatives
HPMLHGED_03318	8.96e-159	-	-	-	L	-	-	-	Integrase core domain
HPMLHGED_03320	4.95e-249	-	-	-	JM	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03321	0.0	fumB	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HPMLHGED_03322	3.59e-285	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03323	7.06e-274	pelA	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	pectate lyase
HPMLHGED_03324	1.44e-311	tolC	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03325	0.0	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_03326	2.1e-248	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_03327	7.4e-226	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPMLHGED_03328	6.51e-122	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPMLHGED_03329	3.15e-187	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03330	1.91e-66	-	-	-	P	-	-	-	RyR domain
HPMLHGED_03331	0.0	-	-	-	P	-	-	-	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HPMLHGED_03333	2.81e-258	-	-	-	D	-	-	-	Tetratricopeptide repeat
HPMLHGED_03335	4.28e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HPMLHGED_03336	1.8e-305	dinF	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
HPMLHGED_03337	7.94e-150	-	-	-	S	-	-	-	COG NOG28155 non supervised orthologous group
HPMLHGED_03338	0.0	-	-	-	M	-	-	-	COG0793 Periplasmic protease
HPMLHGED_03339	6.69e-179	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
HPMLHGED_03340	5.65e-81	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03341	1.8e-83	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HPMLHGED_03342	6.13e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03343	7.61e-102	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPMLHGED_03344	1.41e-54	-	-	-	S	-	-	-	Domain of unknown function (DUF4834)
HPMLHGED_03345	3.96e-163	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPMLHGED_03346	9.81e-165	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HPMLHGED_03347	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HPMLHGED_03348	1.17e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HPMLHGED_03349	6.82e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03350	1.14e-77	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_03351	7.7e-126	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03352	2.1e-161	-	-	-	S	-	-	-	serine threonine protein kinase
HPMLHGED_03353	9.21e-229	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03354	1.24e-192	-	-	-	-	-	-	-	-
HPMLHGED_03355	8.14e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4129)
HPMLHGED_03356	9.58e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03358	5.6e-202	-	-	-	I	-	-	-	Acyl-transferase
HPMLHGED_03359	1.17e-247	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03360	0.0	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03361	9.69e-99	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HPMLHGED_03363	2.54e-234	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_03364	3.98e-159	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_03365	2.56e-95	-	-	-	K	ko:K03088	-	ko00000,ko03021	sigma70 factor
HPMLHGED_03366	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HPMLHGED_03367	6.97e-142	argK	-	-	E	ko:K07588	-	ko00000,ko01000	Lao Ao transport system ATPase
HPMLHGED_03368	6.56e-130	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPMLHGED_03369	1.5e-316	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formyltetrahydrofolate synthetase
HPMLHGED_03370	3.29e-102	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPMLHGED_03371	0.0	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HPMLHGED_03372	0.0	-	-	-	S	ko:K21557	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03373	0.0	-	3.2.1.135	GH13	G	ko:K21575	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 13 family
HPMLHGED_03374	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HPMLHGED_03375	0.0	-	-	-	HP	ko:K21573	-	ko00000,ko02000	TonB dependent receptor
HPMLHGED_03376	0.0	susD	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03377	6.99e-288	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
HPMLHGED_03378	0.0	-	-	-	S	ko:K21571	-	ko00000	Domain of unknown function (DUF5115)
HPMLHGED_03379	0.0	-	3.2.1.1, 3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	M	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
HPMLHGED_03380	5.5e-193	lpxH	3.6.1.54	-	S	ko:K03269	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score
HPMLHGED_03381	6.82e-66	yitW	-	-	S	-	-	-	FeS assembly SUF system protein
HPMLHGED_03382	1.02e-163	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HPMLHGED_03383	1.09e-295	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_03384	8.87e-288	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPMLHGED_03385	1.66e-230	pta	2.3.1.8	-	C	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03386	1.93e-70	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_03387	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
HPMLHGED_03388	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03389	1.82e-227	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_03390	3.18e-97	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_03391	5.2e-180	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPMLHGED_03392	0.0	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
HPMLHGED_03393	1.89e-200	-	-	-	I	-	-	-	COG0657 Esterase lipase
HPMLHGED_03394	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Domain of unknown function (DUF5110)
HPMLHGED_03395	8.12e-105	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HPMLHGED_03396	8.85e-102	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HPMLHGED_03397	3e-89	-	-	-	S	-	-	-	COG NOG31702 non supervised orthologous group
HPMLHGED_03398	3.52e-118	-	-	-	S	-	-	-	COG NOG27987 non supervised orthologous group
HPMLHGED_03399	0.0	mutS_2	-	-	L	-	-	-	DNA mismatch repair protein MutS
HPMLHGED_03400	6.14e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HPMLHGED_03401	1.55e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPMLHGED_03402	4.49e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPMLHGED_03403	5.19e-59	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPMLHGED_03404	2.53e-88	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPMLHGED_03405	3.11e-164	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPMLHGED_03406	9.31e-97	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPMLHGED_03407	1.75e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HPMLHGED_03408	1.13e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPMLHGED_03409	4.74e-212	ddh	1.4.1.16	-	E	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HPMLHGED_03410	1.19e-129	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPMLHGED_03411	6.53e-250	-	-	-	S	-	-	-	COG NOG26961 non supervised orthologous group
HPMLHGED_03412	3.8e-15	-	-	-	-	-	-	-	-
HPMLHGED_03413	8.69e-194	-	-	-	-	-	-	-	-
HPMLHGED_03414	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HPMLHGED_03415	2.62e-283	pepQ	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	xaa-pro dipeptidase K01271
HPMLHGED_03416	0.0	gdh	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HPMLHGED_03417	0.0	ppsA	-	-	GKT	-	-	-	Pyruvate phosphate dikinase, PEP pyruvate binding domain
HPMLHGED_03418	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HPMLHGED_03419	0.0	gdhA	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HPMLHGED_03420	4.83e-30	-	-	-	-	-	-	-	-
HPMLHGED_03421	0.0	maeB	1.1.1.38, 1.1.1.40	-	C	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03422	3.05e-182	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
HPMLHGED_03424	5.81e-277	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_03425	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_03426	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03427	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03428	1.61e-168	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_03429	4.58e-102	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_03431	2e-243	-	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HPMLHGED_03432	0.0	-	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HPMLHGED_03433	0.0	amyS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
HPMLHGED_03434	1.9e-231	rlmF	2.1.1.181	-	J	ko:K06970	-	ko00000,ko01000,ko03009	Specifically methylates the adenine in position 1618 of 23S rRNA
HPMLHGED_03435	3e-272	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease family
HPMLHGED_03436	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HPMLHGED_03437	5.64e-152	-	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HPMLHGED_03438	3.35e-305	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03439	2.05e-315	zraR_2	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HPMLHGED_03440	5.58e-179	-	-	-	S	-	-	-	COG NOG27188 non supervised orthologous group
HPMLHGED_03441	5.31e-202	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
HPMLHGED_03442	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03443	3.84e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
HPMLHGED_03444	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03445	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03446	1.99e-153	pgmB	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HPMLHGED_03447	2.4e-192	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HPMLHGED_03448	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_03449	0.0	-	2.4.1.11	GT3	G	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Starch synthase
HPMLHGED_03450	8.7e-95	ntpK	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG COG0636 F0F1-type ATP synthase, subunit c Archaeal vacuolar-type H -ATPase, subunit K
HPMLHGED_03451	0.0	-	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
HPMLHGED_03452	5.05e-131	-	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Psort location Cytoplasmic, score 8.96
HPMLHGED_03453	3.25e-293	ntpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	ATP synthase alpha beta family, nucleotide-binding domain protein
HPMLHGED_03455	2.23e-37	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_03456	3.1e-188	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03457	1.27e-108	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_03458	1.47e-65	-	-	-	L	-	-	-	HNH endonuclease domain protein
HPMLHGED_03459	9.84e-293	-	-	-	S	ko:K07133	-	ko00000	Domain of unknown function (DUF4143)
HPMLHGED_03460	1.4e-275	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HPMLHGED_03461	3.5e-287	-	-	-	L	-	-	-	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HPMLHGED_03462	0.0	-	-	-	L	-	-	-	Z1 domain
HPMLHGED_03463	2.98e-123	-	-	-	S	-	-	-	Putative PD-(D/E)XK family member, (DUF4420)
HPMLHGED_03464	2.74e-108	-	-	-	-	-	-	-	-
HPMLHGED_03465	1.45e-75	-	-	-	S	-	-	-	HEPN domain
HPMLHGED_03466	6.27e-67	-	-	-	L	-	-	-	Nucleotidyltransferase domain
HPMLHGED_03467	3.29e-258	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HPMLHGED_03468	4.12e-49	-	-	-	S	-	-	-	conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN
HPMLHGED_03469	1.77e-63	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HPMLHGED_03470	7.61e-291	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HPMLHGED_03471	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HPMLHGED_03472	1.71e-116	-	1.16.3.1	-	S	ko:K03594	ko00860,map00860	ko00000,ko00001,ko01000	Ferritin-like domain
HPMLHGED_03473	4.29e-113	-	-	-	-	-	-	-	-
HPMLHGED_03474	1.02e-231	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03475	2.56e-272	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG2812 DNA polymerase III gamma tau subunits
HPMLHGED_03476	5.02e-275	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HPMLHGED_03477	8.5e-243	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_03478	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
HPMLHGED_03480	2.44e-71	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03481	9.52e-17	-	-	-	-	-	-	-	-
HPMLHGED_03482	4.06e-107	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_03483	2.61e-133	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03484	2.48e-112	-	-	-	E	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_03485	1.17e-163	-	-	-	-	-	-	-	-
HPMLHGED_03486	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HPMLHGED_03487	1.23e-163	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_03488	3.84e-265	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HPMLHGED_03489	1.61e-282	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	outer membrane efflux protein
HPMLHGED_03490	0.0	-	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HPMLHGED_03491	7.36e-291	-	-	-	T	-	-	-	COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
HPMLHGED_03492	4.72e-66	-	2.4.1.281	-	G	ko:K16212	-	ko00000,ko01000	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
HPMLHGED_03493	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
HPMLHGED_03495	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPMLHGED_03496	0.0	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
HPMLHGED_03497	3.57e-205	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03498	5.04e-201	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HPMLHGED_03499	9.59e-172	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
HPMLHGED_03500	2.95e-195	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HPMLHGED_03501	1.26e-265	lpxB	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPMLHGED_03502	5.08e-191	-	-	-	S	-	-	-	COG NOG29298 non supervised orthologous group
HPMLHGED_03503	9.07e-196	cdsA	2.7.7.41	-	M	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HPMLHGED_03504	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPMLHGED_03505	2.12e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPMLHGED_03507	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03508	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03509	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
HPMLHGED_03510	0.0	-	-	-	A	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03511	3.77e-267	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HPMLHGED_03512	1.76e-191	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPMLHGED_03513	9.93e-235	-	-	-	S	ko:K07027	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03514	0.0	pepD_2	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Xaa-His dipeptidase
HPMLHGED_03516	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03517	0.0	-	-	-	S	-	-	-	COG2373 Large extracellular alpha-helical protein
HPMLHGED_03518	5.99e-266	-	-	-	S	-	-	-	COG NOG19146 non supervised orthologous group
HPMLHGED_03519	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03520	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03521	3.34e-231	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPMLHGED_03522	3.45e-125	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPMLHGED_03523	1.07e-48	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Iron-only hydrogenase maturation rSAM protein HydE
HPMLHGED_03524	0.0	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Iron-only hydrogenase maturation rSAM protein HydG
HPMLHGED_03525	2.45e-288	hydF	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03526	3.56e-99	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_03527	1.98e-180	-	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HPMLHGED_03529	5.59e-37	-	-	-	-	-	-	-	-
HPMLHGED_03530	0.0	-	-	-	S	-	-	-	COG NOG25960 non supervised orthologous group
HPMLHGED_03531	1.48e-268	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HPMLHGED_03532	0.0	recD2_4	-	-	L	-	-	-	COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
HPMLHGED_03533	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HPMLHGED_03534	1.03e-232	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HPMLHGED_03535	5.62e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03536	1.39e-79	-	-	-	S	-	-	-	COG NOG23405 non supervised orthologous group
HPMLHGED_03537	2.92e-103	-	-	-	S	-	-	-	COG NOG28735 non supervised orthologous group
HPMLHGED_03538	1.34e-188	mazG	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03539	1.46e-95	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03540	0.0	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
HPMLHGED_03541	2.45e-107	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HPMLHGED_03542	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03543	2.51e-311	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_03544	8.57e-139	-	-	-	S	-	-	-	Lipopolysaccharide-assembly, LptC-related
HPMLHGED_03545	2.88e-289	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
HPMLHGED_03546	0.0	ppiD	5.2.1.8	-	O	ko:K01802,ko:K03770	-	ko00000,ko01000,ko03110	COG NOG26630 non supervised orthologous group
HPMLHGED_03547	3.78e-248	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPMLHGED_03548	3.52e-253	-	-	-	L	-	-	-	COG NOG11654 non supervised orthologous group
HPMLHGED_03549	3.32e-263	pdxA	1.1.1.262	-	C	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
HPMLHGED_03550	3.37e-290	fhlA	-	-	K	-	-	-	Sigma-54 interaction domain protein
HPMLHGED_03551	1.57e-119	lptE	-	-	S	-	-	-	COG NOG14471 non supervised orthologous group
HPMLHGED_03552	2.52e-169	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03553	1.84e-65	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HPMLHGED_03554	0.0	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HPMLHGED_03555	1.07e-79	pqqD	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03556	1.44e-61	-	-	-	-	-	-	-	-
HPMLHGED_03557	8.89e-247	-	-	-	S	-	-	-	COG NOG25792 non supervised orthologous group
HPMLHGED_03558	1.92e-67	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPMLHGED_03559	6.78e-111	hypB	-	-	H	ko:K22132	-	ko00000,ko03016	involved in molybdopterin and thiamine biosynthesis family 1
HPMLHGED_03560	2.4e-151	lolD	-	-	V	ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
HPMLHGED_03561	7.56e-214	comEA	-	-	L	-	-	-	COG COG1555 DNA uptake protein and related DNA-binding proteins
HPMLHGED_03562	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HPMLHGED_03563	1.09e-95	fjo27	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_03564	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPMLHGED_03565	0.0	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
HPMLHGED_03566	1.58e-204	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03567	5.55e-168	dacA	-	-	S	-	-	-	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HPMLHGED_03568	5.86e-125	batC	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_03569	2.32e-236	batB	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HPMLHGED_03570	1.44e-227	batA	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HPMLHGED_03571	4.22e-248	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03572	1.16e-207	-	-	-	S	-	-	-	protein (some members contain a von Willebrand factor type A (vWA) domain)
HPMLHGED_03573	4.12e-229	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HPMLHGED_03574	2.35e-263	-	-	-	L	-	-	-	Belongs to the bacterial histone-like protein family
HPMLHGED_03575	2.56e-55	himA	-	-	L	ko:K03530,ko:K04764	-	ko00000,ko03032,ko03036,ko03400	COG0776 Bacterial nucleoid DNA-binding protein
HPMLHGED_03576	1.91e-316	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HPMLHGED_03577	5.58e-221	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPMLHGED_03578	1.54e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF4295)
HPMLHGED_03579	1e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HPMLHGED_03580	2.83e-57	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HPMLHGED_03581	9.75e-277	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HPMLHGED_03582	6.5e-246	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPMLHGED_03583	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
HPMLHGED_03584	4.93e-211	-	-	-	S	-	-	-	COG NOG14441 non supervised orthologous group
HPMLHGED_03585	7.07e-97	-	-	-	S	-	-	-	COG NOG14442 non supervised orthologous group
HPMLHGED_03587	2.26e-266	-	-	-	S	-	-	-	NPCBM-associated, NEW3 domain of alpha-galactosidase
HPMLHGED_03588	1.28e-174	yxlF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location Cytoplasmic, score 9.12
HPMLHGED_03589	4.42e-217	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HPMLHGED_03590	3.88e-270	qseC	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03591	3.28e-157	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPMLHGED_03592	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HPMLHGED_03594	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03595	1.54e-223	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein
HPMLHGED_03596	6.76e-269	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HPMLHGED_03597	4.78e-271	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03598	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03599	6.95e-111	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_03600	6.84e-261	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HPMLHGED_03601	1.2e-139	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HPMLHGED_03602	9.69e-99	-	-	-	S	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HPMLHGED_03603	0.0	-	-	-	S	ko:K07079	-	ko00000	of the aldo keto reductase family
HPMLHGED_03604	0.0	yccM	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03605	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HPMLHGED_03606	7.35e-224	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_03607	1.49e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily K00960
HPMLHGED_03608	8.65e-205	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPMLHGED_03609	3.8e-162	oprM_1	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HPMLHGED_03610	1.6e-269	epsC	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HPMLHGED_03611	8e-296	-	1.1.1.336	-	M	ko:K02472	ko00520,ko05111,map00520,map05111	ko00000,ko00001,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HPMLHGED_03612	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HPMLHGED_03613	3.71e-185	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_03614	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 115
HPMLHGED_03615	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_03617	8.64e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_03618	2.2e-233	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_03619	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03620	3.6e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF5004)
HPMLHGED_03621	1.14e-256	-	-	-	S	-	-	-	Domain of unknown function (DUF4961)
HPMLHGED_03622	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_03623	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03624	0.0	-	-	-	H	-	-	-	CarboxypepD_reg-like domain
HPMLHGED_03625	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HPMLHGED_03626	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_03627	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_03628	5.51e-289	-	3.2.1.197	-	G	ko:K21065	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
HPMLHGED_03629	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HPMLHGED_03630	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMLHGED_03631	1.56e-40	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03633	1.27e-129	-	-	-	-	-	-	-	-
HPMLHGED_03634	1.84e-195	-	-	-	S	-	-	-	Protein of unknown function (DUF1266)
HPMLHGED_03635	1.88e-214	-	-	-	S	-	-	-	Protein of unknown function (DUF3137)
HPMLHGED_03636	8.25e-125	-	-	-	S	ko:K03744	-	ko00000	LemA family
HPMLHGED_03637	9.09e-315	tldD3	-	-	S	ko:K03592	-	ko00000,ko01002	Psort location Cytoplasmic, score 9.26
HPMLHGED_03638	0.0	tldD1	-	-	S	ko:K03568	-	ko00000,ko01002	and their inactivated homologs
HPMLHGED_03641	0.0	-	-	-	E	-	-	-	COG COG2755 Lysophospholipase L1 and related esterases
HPMLHGED_03642	3.76e-67	-	-	-	E	-	-	-	COG NOG19114 non supervised orthologous group
HPMLHGED_03643	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_03644	4.17e-237	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_03645	2.55e-305	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03646	2.49e-145	-	-	-	K	-	-	-	transcriptional regulator, TetR family
HPMLHGED_03647	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HPMLHGED_03648	1.43e-134	fchA	-	-	E	-	-	-	COG3404 Methenyl tetrahydrofolate cyclohydrolase
HPMLHGED_03649	2.42e-301	hutI	3.5.2.7	-	F	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HPMLHGED_03650	3.09e-213	ftcD	2.1.2.5, 4.3.1.4	-	E	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	ko00000,ko00001,ko01000,ko03036,ko04147	Glutamate formiminotransferase
HPMLHGED_03651	0.0	hutU	4.2.1.49	-	H	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HPMLHGED_03652	3.04e-156	-	-	-	S	-	-	-	COG NOG29571 non supervised orthologous group
HPMLHGED_03653	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03654	1.33e-78	-	-	-	-	-	-	-	-
HPMLHGED_03655	5.73e-75	-	-	-	S	-	-	-	Lipocalin-like
HPMLHGED_03656	7e-287	bioF	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Beta-eliminating lyase
HPMLHGED_03657	2.86e-240	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
HPMLHGED_03658	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HPMLHGED_03659	0.0	-	-	-	M	-	-	-	Sulfatase
HPMLHGED_03660	1.44e-86	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_03661	2.67e-220	-	3.5.1.53	-	S	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
HPMLHGED_03662	2.83e-60	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03664	4.12e-48	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HPMLHGED_03665	1e-35	-	-	-	-	-	-	-	-
HPMLHGED_03666	1.11e-199	opuAC	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HPMLHGED_03667	7.14e-191	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine transport system, permease
HPMLHGED_03668	5.27e-280	proV	3.6.3.32	-	S	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	IMP dehydrogenase activity
HPMLHGED_03669	1.22e-282	-	-	-	S	-	-	-	Pfam:DUF2029
HPMLHGED_03670	9.35e-74	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HPMLHGED_03671	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03672	1.22e-161	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03673	4.74e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03674	7.87e-243	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HPMLHGED_03675	3.57e-188	lipB	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03676	0.0	-	-	-	S	-	-	-	COG NOG25407 non supervised orthologous group
HPMLHGED_03677	5.09e-225	-	-	-	S	-	-	-	protein conserved in bacteria
HPMLHGED_03678	9.04e-110	-	-	-	-	-	-	-	-
HPMLHGED_03679	0.0	-	-	-	E	-	-	-	GDSL-like protein
HPMLHGED_03680	2.42e-284	yteR_10	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_03681	8.11e-79	-	-	-	G	-	-	-	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238
HPMLHGED_03682	5.25e-120	-	-	-	S	-	-	-	Domain of unknown function (DUF4959)
HPMLHGED_03683	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HPMLHGED_03684	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03685	3.8e-81	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HPMLHGED_03686	7.68e-48	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HPMLHGED_03687	3.5e-138	rbr	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03689	4.44e-123	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HPMLHGED_03690	1.33e-181	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HPMLHGED_03691	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HPMLHGED_03692	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
HPMLHGED_03693	8.87e-269	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPMLHGED_03694	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2339)
HPMLHGED_03695	2.02e-298	-	3.2.1.130, 3.2.1.198	GH99	S	ko:K21132	-	ko00000,ko01000	Glycosyl hydrolase family 99
HPMLHGED_03696	7.49e-284	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
HPMLHGED_03697	1.95e-252	-	-	-	S	-	-	-	Domain of unknown function (DUF4972)
HPMLHGED_03698	0.0	-	-	-	K	-	-	-	GxGYxY sequence motif in domain of unknown function N-terminal
HPMLHGED_03699	0.0	-	-	-	G	-	-	-	cog cog3537
HPMLHGED_03700	0.0	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HPMLHGED_03701	5.25e-166	-	-	-	S	-	-	-	Protein of unknown function (DUF3823)
HPMLHGED_03702	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_03703	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03704	0.0	-	-	-	T	-	-	-	COG NOG26059 non supervised orthologous group
HPMLHGED_03705	8.17e-286	-	-	-	M	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03706	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HPMLHGED_03707	1.34e-66	-	-	-	S	-	-	-	COG NOG23401 non supervised orthologous group
HPMLHGED_03708	0.0	lptD	-	-	M	-	-	-	COG NOG06415 non supervised orthologous group
HPMLHGED_03709	0.0	surA	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
HPMLHGED_03710	2.84e-200	-	-	-	O	-	-	-	COG NOG23400 non supervised orthologous group
HPMLHGED_03711	0.0	-	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	COG COG0760 Parvulin-like peptidyl-prolyl isomerase
HPMLHGED_03712	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HPMLHGED_03713	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HPMLHGED_03714	2.79e-294	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPMLHGED_03715	2.26e-71	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPMLHGED_03716	1.32e-220	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03717	1.95e-291	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_03718	5.05e-188	-	-	-	C	-	-	-	radical SAM domain protein
HPMLHGED_03719	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HPMLHGED_03720	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HPMLHGED_03721	2.34e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HPMLHGED_03722	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_03723	3.95e-138	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HPMLHGED_03724	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HPMLHGED_03725	1.9e-70	-	-	-	-	-	-	-	-
HPMLHGED_03726	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HPMLHGED_03727	1.62e-107	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_03728	9.25e-214	-	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03729	2.93e-299	-	-	-	G	-	-	-	COG2407 L-fucose isomerase and related
HPMLHGED_03730	1.41e-265	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPMLHGED_03731	4.66e-148	spk1	2.7.11.1, 6.3.2.4	-	S	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01001,ko01011	PASTA domain protein
HPMLHGED_03732	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Psort location Periplasmic, score 9.44
HPMLHGED_03733	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_03734	8.23e-269	ykfB	5.1.1.20, 5.1.1.3	-	M	ko:K01776,ko:K19802	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the mandelate racemase muconate lactonizing enzyme family
HPMLHGED_03735	2.72e-237	ykfC	-	-	M	-	-	-	NlpC P60 family protein
HPMLHGED_03736	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HPMLHGED_03738	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HPMLHGED_03739	9.6e-274	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	COG COG0436 Aspartate tyrosine aromatic aminotransferase
HPMLHGED_03740	9.51e-232	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HPMLHGED_03741	2.82e-280	ybdG_1	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03742	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_03743	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HPMLHGED_03745	1.81e-127	-	-	-	K	-	-	-	Cupin domain protein
HPMLHGED_03746	1.87e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPMLHGED_03747	4.1e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HPMLHGED_03748	6.94e-237	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPMLHGED_03749	5.19e-293	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate synthase
HPMLHGED_03750	1.04e-139	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HPMLHGED_03751	1.89e-100	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HPMLHGED_03753	0.0	rhaB	2.7.1.5, 2.7.1.51	-	G	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HPMLHGED_03754	1.43e-314	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03755	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPMLHGED_03756	4.22e-27	-	-	-	-	-	-	-	-
HPMLHGED_03757	0.0	-	-	-	M	-	-	-	COG NOG37029 non supervised orthologous group
HPMLHGED_03758	6.62e-215	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPMLHGED_03759	1.25e-92	-	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HPMLHGED_03761	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_03762	1.72e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
HPMLHGED_03763	8.97e-59	-	3.4.22.10	-	S	ko:K01364	ko01503,ko02024,map01503,map02024	ko00000,ko00001,ko01000,ko01002	COG NOG19112 non supervised orthologous group
HPMLHGED_03765	1.19e-283	-	-	-	S	-	-	-	Peptidase C10 family
HPMLHGED_03767	3.62e-32	-	-	-	NU	-	-	-	Zinc-dependent metalloprotease
HPMLHGED_03768	5.87e-09	-	-	-	S	-	-	-	Domain of unknown function (DUF4377)
HPMLHGED_03769	7.5e-302	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
HPMLHGED_03770	2.04e-190	-	-	-	-	-	-	-	-
HPMLHGED_03771	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HPMLHGED_03772	2.6e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HPMLHGED_03773	1.48e-217	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HPMLHGED_03774	1.01e-141	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HPMLHGED_03775	2.16e-225	-	-	-	U	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HPMLHGED_03776	1.74e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HPMLHGED_03778	1.25e-303	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HPMLHGED_03779	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HPMLHGED_03780	8.51e-219	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HPMLHGED_03782	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03783	1.71e-162	-	-	-	T	-	-	-	Carbohydrate-binding family 9
HPMLHGED_03784	9.03e-115	lpxA2	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HPMLHGED_03785	1.68e-296	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HPMLHGED_03786	2.92e-290	mexF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_03787	3e-80	-	-	-	-	-	-	-	-
HPMLHGED_03788	0.0	-	-	-	G	-	-	-	COG NOG27433 non supervised orthologous group
HPMLHGED_03789	3.42e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
HPMLHGED_03790	1.12e-268	-	-	-	L	-	-	-	COG NOG19081 non supervised orthologous group
HPMLHGED_03791	2.66e-65	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HPMLHGED_03792	1.32e-74	-	-	-	S	-	-	-	Protein of unknown function DUF86
HPMLHGED_03793	4.11e-129	-	-	-	CO	-	-	-	Redoxin
HPMLHGED_03794	1.6e-94	mip	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	COG COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
HPMLHGED_03796	2.24e-300	gmhA	2.4.1.346	GT4	M	ko:K13668	-	ko00000,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HPMLHGED_03797	0.0	amyA	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 57 family
HPMLHGED_03798	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
HPMLHGED_03799	1.77e-199	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Starch synthase, catalytic domain
HPMLHGED_03800	9.86e-201	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HPMLHGED_03801	5.05e-79	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HPMLHGED_03802	0.0	gltA	1.3.1.1, 1.4.1.13, 1.4.1.14	-	C	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
HPMLHGED_03803	1.32e-92	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03804	1.71e-283	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
HPMLHGED_03805	2.07e-80	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03806	2.79e-112	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HPMLHGED_03807	8.1e-282	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPMLHGED_03808	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HPMLHGED_03809	2.59e-171	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Psort location CytoplasmicMembrane, score 7.88
HPMLHGED_03810	8.17e-147	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HPMLHGED_03811	1.33e-178	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPMLHGED_03812	9.42e-173	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HPMLHGED_03813	7.31e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPMLHGED_03814	3.74e-206	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HPMLHGED_03816	3.63e-66	-	-	-	-	-	-	-	-
HPMLHGED_03818	6.62e-81	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HPMLHGED_03819	0.0	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HPMLHGED_03820	1.62e-253	buk	2.7.2.7	-	H	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HPMLHGED_03821	3.02e-227	-	2.3.1.19, 2.3.1.8	-	C	ko:K00625,ko:K00634	ko00430,ko00620,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00650,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03822	2.54e-205	bglA_1	-	-	G	-	-	-	Glycosyl hydrolase family 16
HPMLHGED_03823	4.26e-221	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HPMLHGED_03824	2.28e-251	ywaD	-	-	S	-	-	-	glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
HPMLHGED_03825	1.19e-93	sufE	-	-	S	ko:K02426	-	ko00000	COG2166 SufE protein probably involved in Fe-S center assembly
HPMLHGED_03826	2.67e-38	-	-	-	K	ko:K07727	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03827	1.82e-146	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03828	4.58e-178	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
HPMLHGED_03830	4.56e-225	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin biosynthesis protein
HPMLHGED_03831	2.08e-151	yihX	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03832	9.94e-91	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03833	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
HPMLHGED_03834	0.0	prc	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HPMLHGED_03835	5.46e-233	-	-	-	G	-	-	-	Kinase, PfkB family
HPMLHGED_03836	3.53e-63	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPMLHGED_03837	1.39e-106	nuoJ	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J)
HPMLHGED_03838	1.01e-98	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPMLHGED_03839	8.1e-261	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HPMLHGED_03840	0.0	nuoC	1.6.5.3	-	C	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPMLHGED_03841	1.66e-143	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPMLHGED_03842	2.61e-76	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HPMLHGED_03843	1.84e-87	-	-	-	-	-	-	-	-
HPMLHGED_03844	0.0	-	-	-	S	-	-	-	Psort location
HPMLHGED_03845	9.82e-118	-	-	-	K	ko:K03088	-	ko00000,ko03021	Bacterial regulatory proteins, luxR family
HPMLHGED_03846	6.45e-45	-	-	-	-	-	-	-	-
HPMLHGED_03847	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase middle domain
HPMLHGED_03848	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HPMLHGED_03849	0.0	-	3.1.1.53	-	S	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HPMLHGED_03850	3.91e-268	-	-	-	S	-	-	-	COGs COG4299 conserved
HPMLHGED_03851	8.47e-169	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03852	8.14e-241	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_03853	4.78e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HPMLHGED_03854	6.71e-241	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_03855	7.43e-312	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_03856	2.87e-248	yteR_9	-	-	E	-	-	-	Glycosyl Hydrolase Family 88
HPMLHGED_03857	4.22e-74	rhaU	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HPMLHGED_03860	3.26e-275	-	-	-	O	-	-	-	COG NOG14454 non supervised orthologous group
HPMLHGED_03861	5.65e-96	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPMLHGED_03862	1.33e-87	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family
HPMLHGED_03863	1.58e-209	-	-	-	EG	-	-	-	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HPMLHGED_03864	3.71e-281	-	-	-	P	-	-	-	Transporter, major facilitator family protein
HPMLHGED_03865	6.74e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03867	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HPMLHGED_03868	9.39e-230	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HPMLHGED_03869	7.34e-63	-	-	-	P	ko:K10716	-	ko00000,ko02000	Ion channel
HPMLHGED_03870	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_03871	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_03872	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HPMLHGED_03873	7.56e-242	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the LDH MDH superfamily
HPMLHGED_03874	2.71e-98	-	-	-	P	ko:K03711	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HPMLHGED_03875	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03876	0.0	-	-	-	S	-	-	-	Fic/DOC family
HPMLHGED_03877	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HPMLHGED_03878	1.23e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPMLHGED_03879	2.82e-87	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HPMLHGED_03880	1.68e-149	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_03881	0.0	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog
HPMLHGED_03882	0.0	-	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HPMLHGED_03883	1.13e-37	-	-	-	S	-	-	-	HicA toxin of bacterial toxin-antitoxin,
HPMLHGED_03884	1.67e-49	-	-	-	S	-	-	-	HicB family
HPMLHGED_03885	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HPMLHGED_03886	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HPMLHGED_03887	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	COG NOG04002 non supervised orthologous group
HPMLHGED_03888	2.35e-287	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HPMLHGED_03889	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HPMLHGED_03891	4.42e-33	-	-	-	-	-	-	-	-
HPMLHGED_03892	4.52e-190	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
HPMLHGED_03893	1.78e-206	-	-	-	S	ko:K06894	-	ko00000	COG2373 Large extracellular alpha-helical protein
HPMLHGED_03894	4.15e-186	-	-	-	K	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain protein
HPMLHGED_03895	2.06e-236	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_03896	9.54e-159	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HPMLHGED_03897	3.53e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF4136)
HPMLHGED_03898	8.53e-117	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
HPMLHGED_03899	4.38e-93	-	-	-	S	-	-	-	COG NOG32529 non supervised orthologous group
HPMLHGED_03901	4.87e-117	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPMLHGED_03902	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I
HPMLHGED_03903	9.68e-134	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Glutamine amidotransferase, class I
HPMLHGED_03904	4.34e-236	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPMLHGED_03905	1.52e-175	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HPMLHGED_03906	3.74e-154	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HPMLHGED_03907	3.84e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPMLHGED_03908	5.64e-255	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HPMLHGED_03909	0.0	-	-	-	S	-	-	-	COG NOG06028 non supervised orthologous group
HPMLHGED_03911	3.5e-81	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HPMLHGED_03912	8.32e-243	-	-	-	M	-	-	-	COG COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HPMLHGED_03913	6.99e-212	-	-	-	M	-	-	-	probably involved in cell wall biogenesis
HPMLHGED_03914	2.62e-145	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 9.26
HPMLHGED_03915	4.5e-135	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03916	8.38e-169	-	-	-	D	ko:K07322	-	ko00000	Hemerythrin HHE cation binding domain protein
HPMLHGED_03917	9.98e-290	purH2	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
HPMLHGED_03918	1.36e-121	fldA	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
HPMLHGED_03919	4.1e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF2023)
HPMLHGED_03920	4.59e-247	-	1.8.5.2	-	S	ko:K16936,ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	TQO small subunit DoxD
HPMLHGED_03921	7.93e-249	-	-	-	-	-	-	-	-
HPMLHGED_03922	2.48e-96	-	-	-	-	-	-	-	-
HPMLHGED_03923	1e-131	-	-	-	-	-	-	-	-
HPMLHGED_03924	5.56e-104	-	-	-	-	-	-	-	-
HPMLHGED_03925	1.57e-102	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HPMLHGED_03926	1.14e-159	mtgA	2.4.1.129	GT51	M	ko:K03814	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HPMLHGED_03927	0.0	-	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
HPMLHGED_03928	1.17e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HPMLHGED_03929	3.2e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HPMLHGED_03930	2e-154	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03931	1.74e-168	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HPMLHGED_03932	5.23e-126	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
HPMLHGED_03933	0.000763	wzy	-	-	S	ko:K19419	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HPMLHGED_03934	1.54e-61	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_03935	4.18e-90	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_03936	1.63e-90	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_03937	8.42e-113	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HPMLHGED_03938	9.53e-136	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HPMLHGED_03939	1.31e-96	-	-	-	S	-	-	-	Glycosyltransferase like family 2
HPMLHGED_03940	2.46e-146	-	-	-	S	-	-	-	PFAM polysaccharide biosynthesis protein
HPMLHGED_03941	5.55e-180	-	-	-	M	-	-	-	Chain length determinant protein
HPMLHGED_03943	5.93e-236	-	-	-	M	-	-	-	Glycosyl transferase family 2
HPMLHGED_03945	5.39e-137	-	-	-	V	-	-	-	HlyD family secretion protein
HPMLHGED_03946	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_03947	3.97e-123	-	-	-	MU	-	-	-	Outer membrane efflux protein
HPMLHGED_03948	8.39e-103	-	-	-	M	-	-	-	Glycosyl transferase, family 2
HPMLHGED_03949	1.75e-136	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_03950	1.58e-94	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_03951	2.4e-281	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_03952	0.0	-	-	-	G	-	-	-	exo-alpha-(2->6)-sialidase activity
HPMLHGED_03953	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
HPMLHGED_03954	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HPMLHGED_03955	5.97e-150	apbE_1	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPMLHGED_03956	0.0	-	-	-	G	-	-	-	COG NOG29805 non supervised orthologous group
HPMLHGED_03957	0.0	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
HPMLHGED_03958	1.58e-41	-	-	-	-	-	-	-	-
HPMLHGED_03959	3.52e-304	-	-	-	S	-	-	-	Tat pathway signal sequence domain protein
HPMLHGED_03960	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_03961	0.0	-	-	-	C	ko:K09181	-	ko00000	CoA binding domain protein
HPMLHGED_03962	1.75e-09	-	-	-	S	-	-	-	RDD family
HPMLHGED_03963	1.84e-10	-	-	-	M	-	-	-	RHS repeat-associated core domain
HPMLHGED_03965	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4925)
HPMLHGED_03966	7.96e-206	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HPMLHGED_03967	4.52e-282	-	-	-	T	-	-	-	Sensor histidine kinase
HPMLHGED_03968	3.01e-166	-	-	-	K	-	-	-	Response regulator receiver domain protein
HPMLHGED_03969	1.18e-294	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HPMLHGED_03971	1.47e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF4907)
HPMLHGED_03972	1.37e-273	nanM	-	-	S	-	-	-	COG NOG23382 non supervised orthologous group
HPMLHGED_03973	0.0	-	-	-	S	-	-	-	COG NOG26034 non supervised orthologous group
HPMLHGED_03975	2.13e-151	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_03976	1.85e-127	marC	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HPMLHGED_03977	9.46e-159	-	-	-	K	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
HPMLHGED_03979	0.0	-	-	-	S	-	-	-	NHL repeat
HPMLHGED_03980	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_03981	0.0	-	-	-	P	-	-	-	SusD family
HPMLHGED_03982	9.51e-245	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_03983	0.0	-	-	-	S	-	-	-	Fibronectin type 3 domain
HPMLHGED_03984	1.6e-154	-	-	-	-	-	-	-	-
HPMLHGED_03985	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HPMLHGED_03987	1.27e-292	-	-	-	V	-	-	-	HlyD family secretion protein
HPMLHGED_03988	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_03990	4.56e-161	-	-	-	-	-	-	-	-
HPMLHGED_03991	1.06e-129	-	-	-	S	-	-	-	JAB-like toxin 1
HPMLHGED_03992	9.82e-234	-	-	-	S	-	-	-	Domain of unknown function (DUF5030)
HPMLHGED_03993	6.64e-234	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPMLHGED_03994	2.48e-294	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_03995	7.81e-200	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HPMLHGED_03996	0.0	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_03997	1.42e-211	-	-	-	S	-	-	-	TIGRFAM methyltransferase FkbM family
HPMLHGED_03998	9.99e-188	-	-	-	-	-	-	-	-
HPMLHGED_03999	3.17e-192	-	-	-	-	-	-	-	-
HPMLHGED_04000	2.21e-17	-	-	-	S	-	-	-	Domain of unknown function (DUF5030)
HPMLHGED_04001	0.0	-	-	-	S	-	-	-	Erythromycin esterase
HPMLHGED_04002	4.81e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF5030)
HPMLHGED_04003	0.0	-	-	-	E	-	-	-	Peptidase M60-like family
HPMLHGED_04004	5.4e-161	-	-	-	-	-	-	-	-
HPMLHGED_04005	9.98e-298	-	-	-	S	-	-	-	Fibronectin type 3 domain
HPMLHGED_04006	5.75e-220	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_04007	0.0	-	-	-	P	-	-	-	SusD family
HPMLHGED_04008	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_04009	0.0	-	-	-	S	-	-	-	NHL repeat
HPMLHGED_04011	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HPMLHGED_04012	3.29e-83	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPMLHGED_04013	9.08e-221	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPMLHGED_04014	0.0	dcp	3.4.15.5, 3.4.24.70	-	E	ko:K01284,ko:K01414	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HPMLHGED_04015	1.03e-108	-	-	-	S	-	-	-	COG NOG30732 non supervised orthologous group
HPMLHGED_04016	1.31e-103	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	Cytidine and deoxycytidylate deaminase zinc-binding region
HPMLHGED_04018	1.18e-44	-	-	-	-	-	-	-	-
HPMLHGED_04019	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HPMLHGED_04020	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
HPMLHGED_04021	5.06e-234	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HPMLHGED_04022	1.91e-186	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HPMLHGED_04023	7.44e-297	-	-	-	-	-	-	-	-
HPMLHGED_04024	1.5e-313	-	-	-	S	-	-	-	COG NOG33609 non supervised orthologous group
HPMLHGED_04025	5.37e-217	-	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HPMLHGED_04026	0.0	-	-	-	S	-	-	-	ABC-type transport system involved in multi-copper enzyme maturation permease component
HPMLHGED_04027	0.0	-	-	-	MU	-	-	-	Outer membrane efflux protein
HPMLHGED_04028	1.42e-247	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Barrel-sandwich domain of CusB or HlyD membrane-fusion
HPMLHGED_04029	0.0	-	-	-	V	ko:K03296	-	ko00000	AcrB/AcrD/AcrF family
HPMLHGED_04030	0.0	-	-	-	V	-	-	-	AcrB/AcrD/AcrF family
HPMLHGED_04031	1.27e-158	-	-	-	-	-	-	-	-
HPMLHGED_04032	0.0	-	-	-	M	ko:K07001	-	ko00000	Phospholipase, patatin family
HPMLHGED_04033	2.95e-283	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_04034	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase, family 20, catalytic domain
HPMLHGED_04035	2.63e-153	-	-	-	S	-	-	-	Iron-binding zinc finger CDGSH type
HPMLHGED_04036	2.31e-133	-	-	-	J	-	-	-	COG COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HPMLHGED_04038	0.0	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HPMLHGED_04039	1.02e-94	-	-	-	S	-	-	-	ACT domain protein
HPMLHGED_04040	1.97e-188	yfiO	-	-	S	ko:K05807	-	ko00000,ko02000	outer membrane assembly lipoprotein YfiO
HPMLHGED_04041	4.8e-72	rpoZ	-	-	S	-	-	-	COG NOG14434 non supervised orthologous group
HPMLHGED_04042	2.75e-95	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_04043	2.63e-85	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HPMLHGED_04044	2.5e-109	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HPMLHGED_04045	2.54e-214	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPMLHGED_04046	1.32e-38	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04047	2.23e-188	-	-	-	S	-	-	-	Phospholipase/Carboxylesterase
HPMLHGED_04048	3.32e-242	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPMLHGED_04049	1.02e-278	spmA	-	-	S	ko:K06373	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04050	5.5e-97	ybeY	-	-	S	-	-	-	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPMLHGED_04051	0.0	-	-	-	O	-	-	-	non supervised orthologous group
HPMLHGED_04052	1.9e-211	-	-	-	-	-	-	-	-
HPMLHGED_04053	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04054	0.0	-	-	-	P	-	-	-	Secretin and TonB N terminus short domain
HPMLHGED_04055	5.06e-280	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_04056	5.57e-129	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_04057	6.83e-312	-	-	-	O	-	-	-	Domain of unknown function (DUF5118)
HPMLHGED_04058	1.14e-106	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HPMLHGED_04059	2.2e-221	-	-	-	S	-	-	-	Domain of unknown function (DUF4959)
HPMLHGED_04060	0.0	-	-	-	E	-	-	-	COG NOG04153 non supervised orthologous group
HPMLHGED_04061	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score
HPMLHGED_04062	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
HPMLHGED_04063	0.0	-	-	-	G	-	-	-	COG NOG26813 non supervised orthologous group
HPMLHGED_04064	6.21e-163	-	-	-	S	-	-	-	Psort location OuterMembrane, score
HPMLHGED_04065	7.01e-209	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HPMLHGED_04066	1.46e-122	isiB	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
HPMLHGED_04067	0.0	bfmBAB	1.2.4.4	-	C	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	dehydrogenase E1 component
HPMLHGED_04068	2.38e-284	bfmBB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
HPMLHGED_04069	4.43e-162	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HPMLHGED_04070	9.3e-317	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dihydrolipoyl dehydrogenase
HPMLHGED_04071	1.85e-208	acm	-	-	M	ko:K07273	-	ko00000	phage tail component domain protein
HPMLHGED_04072	0.0	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HPMLHGED_04073	0.0	-	-	-	M	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Efflux transporter, outer membrane factor lipoprotein, NodT family
HPMLHGED_04074	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_04075	1.82e-165	-	-	-	S	ko:K09704	-	ko00000	Metal-independent alpha-mannosidase (GH125)
HPMLHGED_04076	4.83e-35	-	2.3.1.57	-	K	ko:K03826,ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HPMLHGED_04077	8.23e-112	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_04078	1.79e-59	-	-	-	-	-	-	-	-
HPMLHGED_04079	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HPMLHGED_04080	4.47e-164	-	-	-	V	-	-	-	ATPases associated with a variety of cellular activities
HPMLHGED_04081	7.93e-198	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HPMLHGED_04082	5.46e-161	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HPMLHGED_04083	0.0	nirA	1.7.7.1, 1.8.7.1	-	C	ko:K00366,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HPMLHGED_04084	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HPMLHGED_04085	2.18e-169	ytvI	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.99
HPMLHGED_04086	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPMLHGED_04088	3.1e-174	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPMLHGED_04089	0.0	-	-	-	S	-	-	-	C terminal of Calcineurin-like phosphoesterase
HPMLHGED_04090	3.11e-307	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
HPMLHGED_04091	3.62e-312	-	-	-	S	-	-	-	Domain of unknown function
HPMLHGED_04092	5.06e-313	-	-	-	S	-	-	-	Domain of unknown function (DUF5018)
HPMLHGED_04093	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04094	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04095	2.07e-260	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
HPMLHGED_04096	1.09e-300	ce	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
HPMLHGED_04097	0.0	araE	-	-	P	ko:K08138,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HPMLHGED_04098	1.89e-279	-	-	-	S	-	-	-	Domain of unknown function (DUF5109)
HPMLHGED_04099	0.0	-	-	-	O	-	-	-	FAD dependent oxidoreductase
HPMLHGED_04100	2.46e-291	nagC	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_04102	5.81e-257	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_04103	1.39e-32	-	-	-	-	-	-	-	-
HPMLHGED_04104	6.14e-91	umuD	-	-	L	ko:K03503	-	ko00000,ko01000,ko01002,ko03400	PFAM Peptidase S24 S26A S26B, conserved region
HPMLHGED_04105	7.71e-257	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	COGs COG0389 Nucleotidyltransferase DNA polymerase involved in DNA repair
HPMLHGED_04109	2.59e-107	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HPMLHGED_04110	2.7e-60	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04111	5.1e-43	-	-	-	-	-	-	-	-
HPMLHGED_04112	7.78e-07	-	-	-	-	-	-	-	-
HPMLHGED_04115	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HPMLHGED_04116	2.54e-62	-	-	-	-	-	-	-	-
HPMLHGED_04117	1.73e-196	-	-	-	D	-	-	-	nuclear chromosome segregation
HPMLHGED_04118	2.18e-06	-	-	-	-	-	-	-	-
HPMLHGED_04120	5.81e-56	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HPMLHGED_04122	4.03e-29	-	-	-	-	-	-	-	-
HPMLHGED_04123	3.17e-21	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04125	1.04e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
HPMLHGED_04126	4.78e-08	-	-	-	-	-	-	-	-
HPMLHGED_04127	5.05e-162	-	-	-	V	-	-	-	Abi-like protein
HPMLHGED_04128	1.7e-48	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
HPMLHGED_04130	9.28e-90	-	-	-	-	-	-	-	-
HPMLHGED_04131	2.71e-76	-	-	-	-	-	-	-	-
HPMLHGED_04133	2.32e-32	-	3.1.3.41	-	-	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	-
HPMLHGED_04135	1.94e-52	-	-	-	-	-	-	-	-
HPMLHGED_04136	1.09e-36	-	-	-	-	-	-	-	-
HPMLHGED_04137	7.17e-31	-	-	-	-	-	-	-	-
HPMLHGED_04138	5.93e-156	-	-	-	-	-	-	-	-
HPMLHGED_04139	4.63e-115	moeZ	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	involved in molybdopterin and thiamine biosynthesis family 2
HPMLHGED_04140	8.84e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase TENI
HPMLHGED_04141	3.93e-134	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
HPMLHGED_04142	5.73e-120	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HPMLHGED_04143	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HPMLHGED_04144	0.0	rumA	2.1.1.190	-	H	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPMLHGED_04145	3.37e-220	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HPMLHGED_04146	2.1e-99	-	-	-	-	-	-	-	-
HPMLHGED_04147	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04148	7.78e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4858)
HPMLHGED_04149	1.92e-209	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HPMLHGED_04150	3.34e-256	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HPMLHGED_04151	0.0	-	-	-	KT	-	-	-	Peptidase, M56 family
HPMLHGED_04152	4.03e-82	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
HPMLHGED_04153	4.52e-299	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	) H( ) antiporter that extrudes sodium in exchange for external protons
HPMLHGED_04154	1.33e-269	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_04155	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPMLHGED_04156	4.95e-40	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
HPMLHGED_04158	1.35e-102	-	-	-	S	-	-	-	COG NOG16874 non supervised orthologous group
HPMLHGED_04159	6.95e-191	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 9.97
HPMLHGED_04160	9.2e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family
HPMLHGED_04161	1.63e-56	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04162	1.98e-178	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HPMLHGED_04163	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HPMLHGED_04164	1.57e-129	bglA_1	-	-	G	-	-	-	Glycosyl hydrolase family 16
HPMLHGED_04165	6.69e-314	-	-	-	E	-	-	-	non supervised orthologous group
HPMLHGED_04166	4.19e-122	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
HPMLHGED_04170	4.19e-58	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_04171	4.67e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_04172	7.21e-126	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPMLHGED_04174	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HPMLHGED_04175	5.09e-199	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPMLHGED_04176	1.22e-248	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HPMLHGED_04177	1.99e-118	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HPMLHGED_04178	2.73e-127	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HPMLHGED_04179	4.28e-154	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HPMLHGED_04180	5.9e-233	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HPMLHGED_04181	0.0	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HPMLHGED_04182	9.62e-177	rnfB	-	-	C	ko:K03616	-	ko00000	electron transport complex, RnfABCDGE type, B subunit
HPMLHGED_04183	1.33e-90	-	-	-	T	ko:K03803	-	ko00000,ko03021	Positive regulator of sigma(E), RseC MucC
HPMLHGED_04184	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_04185	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
HPMLHGED_04186	3.37e-219	-	-	-	K	-	-	-	AraC-like ligand binding domain
HPMLHGED_04187	4.57e-162	-	-	-	N	-	-	-	domain, Protein
HPMLHGED_04188	4.66e-201	-	-	-	M	-	-	-	Glycosyl hydrolase family 30 TIM-barrel domain
HPMLHGED_04189	3.23e-277	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_04190	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04191	7.66e-236	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HPMLHGED_04192	1.87e-183	-	-	-	S	-	-	-	Metalloenzyme superfamily
HPMLHGED_04193	3.06e-250	-	-	-	G	-	-	-	COG NOG26813 non supervised orthologous group
HPMLHGED_04194	1.15e-105	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
HPMLHGED_04195	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_04196	2.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HPMLHGED_04197	2.12e-202	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_04198	6.51e-95	-	-	-	S	-	-	-	Immunity protein 68
HPMLHGED_04199	9.37e-36	-	-	-	-	-	-	-	-
HPMLHGED_04203	7.78e-40	-	-	-	-	-	-	-	-
HPMLHGED_04204	4.04e-74	-	-	-	-	-	-	-	-
HPMLHGED_04205	1.11e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF2695)
HPMLHGED_04206	4.04e-197	-	-	-	S	-	-	-	Protein of unknown function (DUF4241)
HPMLHGED_04207	5.65e-27	-	-	-	-	-	-	-	-
HPMLHGED_04209	7.11e-47	-	-	-	-	-	-	-	-
HPMLHGED_04210	3.62e-308	-	-	-	M	-	-	-	TIGRFAM YD repeat
HPMLHGED_04211	3.44e-11	-	-	-	-	-	-	-	-
HPMLHGED_04212	1.4e-81	-	-	-	L	-	-	-	COG NOG31286 non supervised orthologous group
HPMLHGED_04213	5.8e-111	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HPMLHGED_04215	4.22e-154	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HPMLHGED_04216	3.08e-233	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase C-terminal domain
HPMLHGED_04217	7.03e-213	xynZ	-	-	S	-	-	-	Esterase
HPMLHGED_04218	2.23e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HPMLHGED_04219	0.0	-	-	-	-	-	-	-	-
HPMLHGED_04220	0.0	-	-	-	S	-	-	-	NHL repeat
HPMLHGED_04221	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_04222	0.0	-	-	-	P	-	-	-	SusD family
HPMLHGED_04223	3.8e-251	-	-	-	S	-	-	-	Pfam:DUF5002
HPMLHGED_04224	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5005)
HPMLHGED_04225	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3987)
HPMLHGED_04226	6.25e-112	-	-	-	L	-	-	-	regulation of translation
HPMLHGED_04228	1.26e-100	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HPMLHGED_04229	2.06e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HPMLHGED_04231	7.1e-238	-	-	-	M	-	-	-	Peptidase, M23 family
HPMLHGED_04232	6.3e-222	-	4.3.3.7	-	H	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HPMLHGED_04233	5.94e-128	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HPMLHGED_04235	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HPMLHGED_04236	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HPMLHGED_04238	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04239	0.0	-	-	-	P	-	-	-	SusD family
HPMLHGED_04240	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04241	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04242	0.0	-	-	-	S	-	-	-	Putative binding domain, N-terminal
HPMLHGED_04243	0.0	-	-	-	U	-	-	-	Putative binding domain, N-terminal
HPMLHGED_04244	1.1e-281	-	-	-	G	-	-	-	Domain of unknown function (DUF4971)
HPMLHGED_04245	6.1e-255	-	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glyco_18
HPMLHGED_04246	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HPMLHGED_04248	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPMLHGED_04249	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
HPMLHGED_04250	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Psort location Cytoplasmic, score
HPMLHGED_04251	9.33e-49	hupB	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HPMLHGED_04252	2.32e-161	-	3.4.21.105	-	S	ko:K09650	-	ko00000,ko01000,ko01002,ko03029	Psort location CytoplasmicMembrane, score
HPMLHGED_04253	2e-209	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04254	1.1e-255	-	-	-	L	-	-	-	Endonuclease Exonuclease phosphatase family
HPMLHGED_04255	0.0	dcp	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
HPMLHGED_04256	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HPMLHGED_04257	1.6e-83	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
HPMLHGED_04258	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04259	2.88e-254	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04260	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04261	1.34e-152	-	-	-	S	-	-	-	Protein of unknown function (DUF3823)
HPMLHGED_04262	3.55e-286	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_04263	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_04264	5.7e-54	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_04265	0.0	-	-	-	G	-	-	-	COG NOG09951 non supervised orthologous group
HPMLHGED_04266	1.41e-109	-	-	-	S	-	-	-	Protein of unknown function (DUF3828)
HPMLHGED_04267	1.26e-139	-	-	-	-	-	-	-	-
HPMLHGED_04268	5.52e-133	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_04269	0.0	-	-	-	S	-	-	-	TonB-dependent Receptor Plug Domain
HPMLHGED_04270	2.33e-262	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_04271	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04272	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HPMLHGED_04273	0.0	-	-	-	S	-	-	-	IPT/TIG domain
HPMLHGED_04274	2.32e-87	-	-	-	T	-	-	-	Two component regulator propeller
HPMLHGED_04275	3.06e-303	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HPMLHGED_04276	7.16e-132	idi	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04277	1.97e-129	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HPMLHGED_04278	0.0	czcA	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_04279	1.03e-211	-	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_04280	4.14e-235	-	-	-	T	-	-	-	Histidine kinase
HPMLHGED_04281	5.92e-183	-	-	-	K	ko:K02477	-	ko00000,ko02022	LytTr DNA-binding domain protein
HPMLHGED_04282	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_04283	5.29e-196	-	-	-	S	-	-	-	Peptidase of plants and bacteria
HPMLHGED_04284	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_04285	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HPMLHGED_04286	1.17e-42	-	-	-	-	-	-	-	-
HPMLHGED_04287	1.14e-148	-	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Phosphoglycolate phosphatase
HPMLHGED_04288	5.54e-144	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HPMLHGED_04289	1.92e-194	-	-	-	K	-	-	-	Transcriptional regulator
HPMLHGED_04290	1.54e-104	-	-	-	S	-	-	-	4Fe-4S single cluster domain
HPMLHGED_04291	9.42e-203	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04293	0.000347	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall hydrolase
HPMLHGED_04294	2.56e-41	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HPMLHGED_04295	7.36e-72	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04296	3.86e-164	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Domain of unknown function (DUF1735)
HPMLHGED_04297	0.0	-	-	-	S	-	-	-	IPT TIG domain protein
HPMLHGED_04298	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04299	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	Psort location OuterMembrane, score
HPMLHGED_04300	1.38e-220	-	-	-	S	-	-	-	Domain of unknown function (DUF4361)
HPMLHGED_04301	2.42e-311	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_04302	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 76
HPMLHGED_04303	4.57e-163	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_04304	4.16e-223	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_04305	3.4e-266	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_04306	0.0	csxA_4	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_04307	0.0	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HPMLHGED_04308	1.52e-284	-	3.2.1.197	-	G	ko:K21065	-	ko00000,ko01000	beta-1,4-mannooligosaccharide phosphorylase
HPMLHGED_04309	2.05e-260	-	-	-	S	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HPMLHGED_04311	0.0	-	-	-	O	-	-	-	COG NOG25094 non supervised orthologous group
HPMLHGED_04312	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HPMLHGED_04313	8.14e-215	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HPMLHGED_04314	1.42e-211	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Psort location Cytoplasmic, score 8.96
HPMLHGED_04315	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_04316	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score
HPMLHGED_04318	1.5e-205	nuoF	1.12.1.3, 1.6.5.3	-	C	ko:K00335,ko:K18331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region
HPMLHGED_04319	0.0	hndD	1.12.1.3, 1.17.1.9	-	C	ko:K00123,ko:K18332	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	COG COG4624 Iron only hydrogenase large subunit, C-terminal domain
HPMLHGED_04320	4.47e-113	hndA	1.12.1.3	-	C	ko:K18330	-	ko00000,ko01000	COG COG1905 NADH ubiquinone oxidoreductase 24 kD subunit
HPMLHGED_04321	1.04e-249	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HPMLHGED_04323	1.25e-139	actP	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Copper-exporting ATPase
HPMLHGED_04324	2.77e-41	-	-	-	P	-	-	-	mercury ion transmembrane transporter activity
HPMLHGED_04325	2.44e-120	-	-	-	C	-	-	-	Nitroreductase family
HPMLHGED_04326	2.35e-211	-	-	-	C	-	-	-	Elongator protein 3, MiaB family, Radical SAM
HPMLHGED_04327	5.57e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HPMLHGED_04328	3.85e-125	-	-	-	H	-	-	-	RibD C-terminal domain
HPMLHGED_04329	4.15e-243	-	-	-	I	-	-	-	pectin acetylesterase
HPMLHGED_04330	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HPMLHGED_04331	1.04e-249	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HPMLHGED_04332	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04333	3.34e-163	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HPMLHGED_04334	0.0	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Domain of unknown function (DUF5127)
HPMLHGED_04335	0.0	-	-	-	E	-	-	-	non supervised orthologous group
HPMLHGED_04336	4.31e-91	-	-	-	S	-	-	-	protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
HPMLHGED_04337	4.4e-87	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HPMLHGED_04338	7.96e-08	-	-	-	S	-	-	-	NVEALA protein
HPMLHGED_04339	9.88e-189	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HPMLHGED_04340	3.78e-16	-	-	-	S	-	-	-	No significant database matches
HPMLHGED_04341	1.54e-21	-	-	-	-	-	-	-	-
HPMLHGED_04342	7.36e-272	-	-	-	S	-	-	-	ATPase (AAA superfamily)
HPMLHGED_04343	3.87e-231	-	-	-	-	-	-	-	-
HPMLHGED_04344	2.43e-254	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HPMLHGED_04345	8.19e-122	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_04346	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HPMLHGED_04348	4.05e-186	znuC	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HPMLHGED_04349	7.09e-223	mntA	-	-	P	ko:K09815,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin
HPMLHGED_04350	9.77e-171	mnmC	-	-	S	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_04351	1.85e-53	yqaA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_04352	2.22e-21	-	-	-	-	-	-	-	-
HPMLHGED_04353	4.13e-277	yqhD	-	-	C	ko:K08325	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HPMLHGED_04354	6.39e-313	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HPMLHGED_04355	5.68e-135	-	-	-	S	-	-	-	COG NOG26558 non supervised orthologous group
HPMLHGED_04356	3.75e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04357	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
HPMLHGED_04359	0.0	-	-	-	E	-	-	-	Pfam:SusD
HPMLHGED_04360	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04361	7.55e-242	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HPMLHGED_04362	4.39e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HPMLHGED_04363	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_04364	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPMLHGED_04365	1.04e-202	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HPMLHGED_04366	3.07e-240	-	-	-	G	-	-	-	Putative glycoside hydrolase Family 18, chitinase_18
HPMLHGED_04367	2.68e-295	-	-	-	S	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HPMLHGED_04368	5.83e-222	-	-	-	S	-	-	-	Domain of unknown function (DUF1735)
HPMLHGED_04369	5.2e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HPMLHGED_04370	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HPMLHGED_04371	2.82e-279	xynB	-	-	I	-	-	-	pectin acetylesterase
HPMLHGED_04372	2.02e-171	-	-	-	-	-	-	-	-
HPMLHGED_04373	7.69e-253	-	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HPMLHGED_04374	1.14e-105	-	-	-	KT	-	-	-	Bacterial transcription activator, effector binding domain
HPMLHGED_04375	2.77e-242	-	-	-	K	ko:K13652	-	ko00000,ko03000	Bacterial transcription activator, effector binding domain
HPMLHGED_04379	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04380	1.42e-61	-	-	-	P	ko:K08364	-	ko00000,ko02000	Heavy metal-associated domain protein
HPMLHGED_04381	9.79e-205	-	4.2.2.20, 4.2.2.21	-	H	ko:K08961	-	ko00000,ko01000	Chondroitin sulfate ABC lyase
HPMLHGED_04382	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HPMLHGED_04383	5.02e-188	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04384	0.0	-	2.7.11.1	-	L	ko:K08282	-	ko00000,ko01000	SNF2 family N-terminal domain
HPMLHGED_04385	1.07e-259	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HPMLHGED_04386	0.0	-	-	-	H	-	-	-	GH3 auxin-responsive promoter
HPMLHGED_04387	1.41e-243	pfkA	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HPMLHGED_04388	4.03e-181	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPMLHGED_04389	2.92e-300	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HPMLHGED_04390	1.89e-105	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPMLHGED_04391	4.76e-87	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPMLHGED_04392	1.1e-61	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04393	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPMLHGED_04394	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPMLHGED_04395	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPMLHGED_04397	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HPMLHGED_04398	2.67e-151	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPMLHGED_04399	2.25e-210	-	-	-	EG	ko:K08978	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04400	4.66e-148	-	-	-	S	-	-	-	COG NOG19149 non supervised orthologous group
HPMLHGED_04401	1.65e-267	mdsC	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04402	0.0	-	-	-	EG	-	-	-	Protein of unknown function (DUF2723)
HPMLHGED_04403	2.35e-246	-	-	-	S	-	-	-	Tetratricopeptide repeat
HPMLHGED_04404	2.63e-149	-	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	HAD hydrolase, family IA, variant 3
HPMLHGED_04405	1.87e-70	-	-	-	Q	-	-	-	COG3458 Acetyl esterase (deacetylase)
HPMLHGED_04406	2.27e-98	-	-	-	-	-	-	-	-
HPMLHGED_04407	0.0	udk2	2.7.1.48	-	FJ	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase Uridine kinase family
HPMLHGED_04408	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04409	3.89e-267	-	3.1.3.97	-	S	ko:K07053	-	ko00000,ko01000	Domain of unknown function
HPMLHGED_04410	0.0	-	-	-	S	-	-	-	NHL repeat
HPMLHGED_04411	5.57e-164	-	-	-	S	ko:K07058	-	ko00000	Virulence factor BrkB
HPMLHGED_04412	9.61e-246	-	-	-	M	-	-	-	ompA family
HPMLHGED_04413	9.11e-106	-	-	-	S	-	-	-	COG NOG17277 non supervised orthologous group
HPMLHGED_04414	7.62e-126	-	-	-	T	-	-	-	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HPMLHGED_04415	1.06e-69	sugE	-	-	P	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein, SMR family
HPMLHGED_04416	1.28e-308	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04417	3.38e-122	-	-	-	T	-	-	-	Cyclic nucleotide-monophosphate binding domain
HPMLHGED_04418	4.38e-209	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HPMLHGED_04419	1.91e-98	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase like
HPMLHGED_04420	2.82e-198	-	-	-	S	-	-	-	aldo keto reductase family
HPMLHGED_04421	5.56e-142	-	-	-	S	-	-	-	DJ-1/PfpI family
HPMLHGED_04423	2.63e-209	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HPMLHGED_04424	6.4e-201	-	-	-	-	-	-	-	-
HPMLHGED_04425	1.88e-221	-	-	-	K	-	-	-	transcriptional regulator pa4120 SWALL Q9HWR1 (EMBL AE004828) (303 aa) fasta scores E()
HPMLHGED_04426	1.78e-240	-	-	-	C	-	-	-	aldo keto reductase
HPMLHGED_04427	3e-54	-	-	-	-	-	-	-	-
HPMLHGED_04428	1.05e-81	-	-	-	-	-	-	-	-
HPMLHGED_04429	2.15e-66	-	-	-	S	-	-	-	Helix-turn-helix domain
HPMLHGED_04431	2.63e-94	-	-	-	-	-	-	-	-
HPMLHGED_04432	1.58e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
HPMLHGED_04433	5.67e-64	-	-	-	K	-	-	-	Helix-turn-helix domain
HPMLHGED_04434	3.87e-57	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
HPMLHGED_04435	2.99e-55	-	-	-	S	-	-	-	MerR HTH family regulatory protein
HPMLHGED_04436	2.42e-123	-	-	-	K	-	-	-	SIR2-like domain
HPMLHGED_04437	2.46e-290	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HPMLHGED_04438	8.54e-69	-	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04439	7.28e-174	ydcV	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HPMLHGED_04440	0.0	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location Periplasmic, score 9.44
HPMLHGED_04441	2.08e-145	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04442	1.57e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF4840)
HPMLHGED_04443	0.0	-	-	-	T	-	-	-	helix_turn_helix, arabinose operon control protein
HPMLHGED_04444	1.14e-231	-	-	-	S	-	-	-	Domain of unknown function (DUF4973)
HPMLHGED_04445	2.34e-135	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HPMLHGED_04446	1.63e-136	-	-	-	G	-	-	-	Glycosyl hydrolases family 18
HPMLHGED_04447	3.64e-295	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HPMLHGED_04449	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPMLHGED_04450	7.48e-133	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPMLHGED_04451	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HPMLHGED_04452	6.17e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPMLHGED_04453	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPMLHGED_04454	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor
HPMLHGED_04456	2.16e-274	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HPMLHGED_04457	8.53e-38	rubR	-	-	C	-	-	-	Psort location Cytoplasmic, score
HPMLHGED_04458	1.88e-106	-	-	-	L	-	-	-	DNA-binding protein
HPMLHGED_04459	8.49e-144	-	-	-	L	-	-	-	COG NOG29822 non supervised orthologous group
HPMLHGED_04460	9.22e-159	-	-	-	S	-	-	-	Pfam:DUF5002
HPMLHGED_04461	0.0	-	-	-	-	-	-	-	-
HPMLHGED_04462	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04463	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04464	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5018)
HPMLHGED_04465	9.07e-302	-	-	-	C	-	-	-	Domain of unknown function (DUF4855)
HPMLHGED_04466	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
HPMLHGED_04467	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HPMLHGED_04468	1.7e-64	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
HPMLHGED_04469	1.64e-147	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
HPMLHGED_04470	4.83e-39	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04471	6.34e-218	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04472	2.19e-166	-	-	-	E	-	-	-	COG NOG09493 non supervised orthologous group
HPMLHGED_04473	2.08e-227	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_04474	4.58e-267	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HPMLHGED_04475	9.13e-225	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	glucan 1,4-alpha-glucosidase activity
HPMLHGED_04476	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HPMLHGED_04477	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
HPMLHGED_04478	3.36e-280	nagZ2	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HPMLHGED_04479	1.67e-86	-	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glyco_18
HPMLHGED_04480	4.51e-137	-	-	-	S	-	-	-	Domain of unknown function (DUF5018)
HPMLHGED_04481	1.23e-228	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HPMLHGED_04482	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04483	0.0	-	-	-	-	-	-	-	-
HPMLHGED_04484	0.0	kpsD	-	-	M	-	-	-	COG1596 Periplasmic protein involved in polysaccharide export
HPMLHGED_04485	4.14e-168	-	-	-	M	-	-	-	Chain length determinant protein
HPMLHGED_04486	9.63e-201	tagO	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04487	1.48e-255	-	1.1.1.336	-	M	ko:K02472	ko00520,ko05111,map00520,map05111	ko00000,ko00001,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HPMLHGED_04488	4.9e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04490	7.86e-110	-	-	-	S	-	-	-	COG NOG11144 non supervised orthologous group
HPMLHGED_04491	7.21e-118	-	-	-	G	-	-	-	polysaccharide deacetylase
HPMLHGED_04492	1.89e-89	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HPMLHGED_04494	2.88e-139	-	-	-	M	-	-	-	Glycosyl transferases group 1
HPMLHGED_04495	2.38e-61	-	2.3.1.30	-	E	ko:K00640,ko:K03819	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HPMLHGED_04496	2.85e-214	-	-	-	O	-	-	-	Highly conserved protein containing a thioredoxin domain
HPMLHGED_04497	3.15e-127	-	2.4.1.180	GT26	M	ko:K02852	-	ko00000,ko01000,ko01003	Belongs to the glycosyltransferase 26 family
HPMLHGED_04498	1.2e-228	-	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
HPMLHGED_04499	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HPMLHGED_04500	1.53e-74	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HPMLHGED_04501	2.17e-81	ridA	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HPMLHGED_04502	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Folylpolyglutamate synthase
HPMLHGED_04503	1.07e-314	ybeZ_1	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HPMLHGED_04504	7.55e-218	preA	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HPMLHGED_04505	5.64e-157	yggS	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPMLHGED_04506	3.26e-111	-	-	-	S	-	-	-	COG NOG14445 non supervised orthologous group
HPMLHGED_04507	1.26e-124	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HPMLHGED_04508	1.08e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HPMLHGED_04509	2.46e-216	-	-	-	M	-	-	-	COG NOG19097 non supervised orthologous group
HPMLHGED_04510	9.13e-151	dedA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_04511	5.29e-274	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HPMLHGED_04512	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glutamine--tRNA ligase
HPMLHGED_04513	2.94e-206	-	-	-	K	-	-	-	WYL domain
HPMLHGED_04514	1.53e-34	XK27_07105	-	-	K	ko:K07729	-	ko00000,ko03000	sequence-specific DNA binding
HPMLHGED_04515	1.33e-243	-	-	-	L	-	-	-	restriction
HPMLHGED_04516	0.0	-	-	-	L	-	-	-	restriction endonuclease
HPMLHGED_04517	4.38e-51	-	-	-	M	-	-	-	Peptidase family M23
HPMLHGED_04518	7.76e-186	-	-	-	-	-	-	-	-
HPMLHGED_04519	1.12e-83	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPMLHGED_04520	8.42e-69	-	-	-	S	-	-	-	Pentapeptide repeat protein
HPMLHGED_04521	6.5e-306	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPMLHGED_04522	1.43e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HPMLHGED_04523	4.05e-89	-	-	-	-	-	-	-	-
HPMLHGED_04524	7.21e-261	-	-	-	-	-	-	-	-
HPMLHGED_04525	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HPMLHGED_04526	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HPMLHGED_04527	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
HPMLHGED_04528	1.63e-96	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPMLHGED_04529	2.21e-113	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPMLHGED_04530	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HPMLHGED_04531	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPMLHGED_04532	1.46e-306	waaA	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Psort location Cytoplasmic, score 8.96
HPMLHGED_04533	7.78e-114	dapH	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HPMLHGED_04534	0.0	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HPMLHGED_04535	6.01e-33	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HPMLHGED_04536	8.06e-201	xerC	-	-	D	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HPMLHGED_04537	3.07e-58	raiA	-	-	J	ko:K05808	-	ko00000,ko03009	Ribosomal subunit interface protein
HPMLHGED_04539	1.87e-102	-	-	-	E	-	-	-	Glyoxalase-like domain
HPMLHGED_04540	1.21e-53	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HPMLHGED_04542	4.22e-102	-	-	-	L	-	-	-	COG NOG31453 non supervised orthologous group
HPMLHGED_04543	1.01e-12	-	-	-	-	-	-	-	-
HPMLHGED_04544	1.71e-118	-	-	-	-	-	-	-	-
HPMLHGED_04548	3.24e-218	-	-	-	-	-	-	-	-
HPMLHGED_04555	2.36e-100	-	-	-	S	-	-	-	YopX protein
HPMLHGED_04556	8.23e-65	-	-	-	-	-	-	-	-
HPMLHGED_04557	2.77e-312	wzc	-	-	D	ko:K16692	-	ko00000,ko01000,ko01001	protein tyrosine kinase activity
HPMLHGED_04558	1.03e-197	-	-	-	L	-	-	-	Phage integrase family
HPMLHGED_04559	4.61e-273	-	-	-	L	-	-	-	Arm DNA-binding domain
HPMLHGED_04561	0.0	alaC	-	-	E	-	-	-	Aminotransferase, class I II
HPMLHGED_04562	1.04e-141	-	-	-	K	ko:K07735	-	ko00000,ko03000	Belongs to the UPF0301 (AlgH) family
HPMLHGED_04563	1.34e-131	speG	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase, gnat family
HPMLHGED_04564	1.65e-97	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HPMLHGED_04565	1.25e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPMLHGED_04566	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPMLHGED_04567	4.21e-144	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HPMLHGED_04568	1.07e-131	-	-	-	S	-	-	-	COG NOG28221 non supervised orthologous group
HPMLHGED_04570	8.95e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HPMLHGED_04572	1.17e-246	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)