Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HELMLDPP_00001	5.44e-230	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_00002	1.2e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_00003	2.21e-61	-	-	-	-	-	-	-	-
HELMLDPP_00004	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HELMLDPP_00005	7.44e-159	-	-	-	L	-	-	-	DNA-binding protein
HELMLDPP_00006	6.63e-136	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_00007	3.76e-244	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_00008	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00009	7.52e-236	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00010	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HELMLDPP_00011	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_00012	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_00013	2.1e-110	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HELMLDPP_00014	5.93e-214	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_00015	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00016	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_00017	0.0	-	-	-	P	-	-	-	Protein of unknown function (DUF229)
HELMLDPP_00019	2.62e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HELMLDPP_00020	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_00021	0.0	-	-	-	G	-	-	-	beta-galactosidase
HELMLDPP_00022	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_00023	3.78e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF4858)
HELMLDPP_00024	0.0	alr	5.1.1.1	-	M	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HELMLDPP_00025	1.31e-244	-	-	-	E	-	-	-	GSCFA family
HELMLDPP_00026	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HELMLDPP_00027	0.0	trkA	-	-	C	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems NAD-binding component
HELMLDPP_00028	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00029	3.58e-85	-	-	-	-	-	-	-	-
HELMLDPP_00030	5.7e-71	nuoA	1.6.5.3	-	C	ko:K00330	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HELMLDPP_00031	1.53e-144	nuoB	1.6.5.3	-	C	ko:K00331	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HELMLDPP_00032	0.0	nuoC	1.6.5.3	-	C	ko:K00333,ko:K13378	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HELMLDPP_00033	1.18e-253	nuoH	1.6.5.3	-	C	ko:K00337	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HELMLDPP_00034	1.11e-91	nuoI	1.6.5.3	-	C	ko:K00338	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HELMLDPP_00035	1.58e-106	ndhG	1.6.5.3	-	C	ko:K00339	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	subunit 6
HELMLDPP_00036	1.18e-58	nuoK	1.6.5.3	-	C	ko:K00340	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HELMLDPP_00037	0.0	nuoL	1.6.5.3	-	CP	ko:K00341	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit
HELMLDPP_00038	0.0	nuoM	1.6.5.3	-	C	ko:K00342	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	proton-translocating NADH-quinone oxidoreductase, chain M
HELMLDPP_00039	0.0	nuoN	1.6.5.3	-	C	ko:K00343	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HELMLDPP_00040	4.54e-306	-	-	-	O	-	-	-	Glycosyl Hydrolase Family 88
HELMLDPP_00041	4.75e-92	-	-	-	T	-	-	-	Histidine kinase-like ATPases
HELMLDPP_00042	2.06e-46	-	-	-	T	-	-	-	Histidine kinase
HELMLDPP_00043	8.23e-88	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HELMLDPP_00044	2.28e-118	-	-	-	T	-	-	-	Histidine kinase
HELMLDPP_00045	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_00046	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00047	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00048	9.09e-150	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00049	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00050	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_00051	6.47e-285	cobW	-	-	S	-	-	-	CobW P47K family protein
HELMLDPP_00052	0.0	fucA	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HELMLDPP_00054	2.49e-277	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG2706 3-carboxymuconate cyclase
HELMLDPP_00055	9.52e-240	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_00056	0.0	-	-	-	N	-	-	-	COG NOG06100 non supervised orthologous group
HELMLDPP_00057	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
HELMLDPP_00058	4.56e-105	-	-	-	K	-	-	-	Transcription termination factor nusG
HELMLDPP_00059	5.84e-259	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_00060	1.1e-159	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_00062	1.24e-99	-	-	-	S	-	-	-	Fic/DOC family
HELMLDPP_00063	0.0	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_00064	4.54e-59	-	-	-	-	-	-	-	-
HELMLDPP_00065	5.51e-164	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Cellulose biosynthesis protein BcsQ
HELMLDPP_00066	1.71e-53	-	-	-	-	-	-	-	-
HELMLDPP_00067	2.73e-197	-	-	-	L	-	-	-	D12 class N6 adenine-specific DNA methyltransferase
HELMLDPP_00068	7.04e-53	-	-	-	-	-	-	-	-
HELMLDPP_00069	1.25e-105	-	-	-	-	-	-	-	-
HELMLDPP_00070	0.0	-	-	-	KL	-	-	-	CRISPR-associated helicase, Cas3
HELMLDPP_00071	1.07e-68	-	-	-	-	-	-	-	-
HELMLDPP_00072	0.0	-	-	-	U	-	-	-	TraM recognition site of TraD and TraG
HELMLDPP_00073	4.99e-223	-	-	-	-	-	-	-	-
HELMLDPP_00074	3.96e-120	-	-	-	-	-	-	-	-
HELMLDPP_00076	4.32e-232	-	-	-	S	-	-	-	Putative amidoligase enzyme
HELMLDPP_00077	4.51e-54	-	-	-	-	-	-	-	-
HELMLDPP_00079	0.0	-	-	-	L	-	-	-	Integrase core domain
HELMLDPP_00080	2.49e-136	-	-	-	L	-	-	-	IstB-like ATP binding protein
HELMLDPP_00081	6.42e-37	-	-	-	-	-	-	-	-
HELMLDPP_00082	1.77e-151	-	-	-	-	-	-	-	-
HELMLDPP_00083	3.74e-35	-	-	-	-	-	-	-	-
HELMLDPP_00084	3.48e-103	-	-	-	L	-	-	-	ATPase involved in DNA repair
HELMLDPP_00085	1.05e-13	-	-	-	L	-	-	-	ATPase involved in DNA repair
HELMLDPP_00086	6.26e-19	-	-	-	L	-	-	-	ATPase involved in DNA repair
HELMLDPP_00088	8.73e-121	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HELMLDPP_00089	1.5e-44	-	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HELMLDPP_00090	5.89e-153	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00091	2.21e-21	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00092	1.39e-20	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00093	3.9e-57	-	-	-	-	-	-	-	-
HELMLDPP_00094	2.78e-195	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
HELMLDPP_00095	8.95e-110	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HELMLDPP_00096	4.81e-36	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HELMLDPP_00097	8.13e-215	-	-	-	C	-	-	-	Flavodoxin
HELMLDPP_00098	3.03e-142	-	-	-	C	-	-	-	Flavodoxin
HELMLDPP_00099	1e-57	-	-	-	C	-	-	-	Flavodoxin
HELMLDPP_00100	4.4e-144	-	-	-	K	-	-	-	Transcriptional regulator
HELMLDPP_00101	2.94e-198	-	-	-	S	-	-	-	metal-dependent hydrolase with the TIM-barrel fold
HELMLDPP_00102	1.14e-142	-	-	-	C	-	-	-	Flavodoxin
HELMLDPP_00103	2.78e-251	-	-	-	C	-	-	-	aldo keto reductase
HELMLDPP_00104	1.69e-298	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HELMLDPP_00105	7.74e-204	-	-	-	EG	-	-	-	EamA-like transporter family
HELMLDPP_00106	5.37e-248	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
HELMLDPP_00107	1.9e-156	-	-	-	H	-	-	-	RibD C-terminal domain
HELMLDPP_00108	8.03e-276	-	-	-	C	-	-	-	aldo keto reductase
HELMLDPP_00109	1.62e-174	-	-	-	IQ	-	-	-	KR domain
HELMLDPP_00110	6.9e-32	-	-	-	S	-	-	-	maltose O-acetyltransferase activity
HELMLDPP_00111	8.28e-135	-	-	-	C	-	-	-	Flavodoxin
HELMLDPP_00112	8.48e-204	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	protein contains double-stranded beta-helix domain
HELMLDPP_00113	1.77e-197	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HELMLDPP_00114	2.4e-193	-	-	-	IQ	-	-	-	Short chain dehydrogenase
HELMLDPP_00115	6.8e-296	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HELMLDPP_00116	0.0	-	-	-	V	-	-	-	MATE efflux family protein
HELMLDPP_00117	8.46e-153	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HELMLDPP_00118	2.46e-127	-	-	-	S	-	-	-	Hexapeptide repeat of succinyl-transferase
HELMLDPP_00119	4.38e-105	-	-	-	I	-	-	-	sulfurtransferase activity
HELMLDPP_00120	8.23e-43	-	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Tautomerase enzyme
HELMLDPP_00121	2.17e-209	-	-	-	S	-	-	-	aldo keto reductase family
HELMLDPP_00122	9.13e-203	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HELMLDPP_00123	4.34e-142	-	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	COG COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HELMLDPP_00124	2.03e-28	-	-	-	EG	-	-	-	membrane
HELMLDPP_00125	7.89e-166	-	-	-	EG	-	-	-	membrane
HELMLDPP_00126	1.8e-249	-	-	-	I	-	-	-	PAP2 family
HELMLDPP_00127	3.81e-190	-	-	-	T	-	-	-	Histidine kinase
HELMLDPP_00128	1.04e-144	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_00129	1.6e-69	-	-	-	S	ko:K08978	-	ko00000,ko02000	EamA-like transporter family
HELMLDPP_00130	0.0	cusA	-	-	V	ko:K07787	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_00132	1.12e-154	-	-	-	MU	-	-	-	Outer membrane efflux protein
HELMLDPP_00134	9.69e-77	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_00135	1.6e-75	-	-	-	-	-	-	-	-
HELMLDPP_00136	1.68e-179	-	-	-	K	-	-	-	Transcriptional regulator
HELMLDPP_00138	1.19e-50	-	-	-	S	-	-	-	Helix-turn-helix domain
HELMLDPP_00141	3.4e-202	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HELMLDPP_00145	3.82e-95	-	-	-	-	-	-	-	-
HELMLDPP_00146	4.54e-59	-	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	bacterial (prokaryotic) histone like domain
HELMLDPP_00147	2.78e-169	-	-	-	-	-	-	-	-
HELMLDPP_00148	2.47e-180	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HELMLDPP_00150	2.25e-105	-	-	-	-	-	-	-	-
HELMLDPP_00151	2.36e-32	-	-	-	-	-	-	-	-
HELMLDPP_00152	3.04e-132	-	-	-	-	-	-	-	-
HELMLDPP_00153	3.33e-243	-	-	-	H	-	-	-	C-5 cytosine-specific DNA methylase
HELMLDPP_00155	4.65e-134	-	-	-	-	-	-	-	-
HELMLDPP_00156	1.03e-179	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00157	2.73e-127	-	-	-	-	-	-	-	-
HELMLDPP_00158	1.8e-30	-	-	-	-	-	-	-	-
HELMLDPP_00161	3.39e-199	-	-	-	EH	-	-	-	Phosphoadenosine phosphosulfate reductase family
HELMLDPP_00163	8.14e-168	-	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HELMLDPP_00169	1.09e-110	-	-	-	L	-	-	-	Methyltransferase domain
HELMLDPP_00170	1.02e-42	-	-	-	-	-	-	-	-
HELMLDPP_00171	1.66e-26	-	-	-	S	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
HELMLDPP_00172	2.97e-48	-	-	-	S	-	-	-	DNA N-6-adenine-methyltransferase (Dam)
HELMLDPP_00173	4.59e-58	-	-	-	-	-	-	-	-
HELMLDPP_00175	4.71e-301	rtcB	6.5.1.3	-	S	ko:K14415	-	ko00000,ko01000,ko03016	tRNA-splicing ligase RtcB
HELMLDPP_00177	1.78e-123	-	-	-	-	-	-	-	-
HELMLDPP_00181	9.31e-26	-	-	-	L	-	-	-	Domain of unknown function (DUF3127)
HELMLDPP_00182	8.27e-130	-	-	-	-	-	-	-	-
HELMLDPP_00184	4.08e-67	-	-	-	-	-	-	-	-
HELMLDPP_00185	9.4e-100	-	-	-	-	-	-	-	-
HELMLDPP_00186	1.51e-57	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00187	7.64e-294	-	-	-	S	-	-	-	Phage minor structural protein
HELMLDPP_00188	1.88e-83	-	-	-	-	-	-	-	-
HELMLDPP_00189	4.35e-79	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00191	3.05e-194	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HELMLDPP_00192	8.69e-313	-	-	-	-	-	-	-	-
HELMLDPP_00193	4.18e-238	-	-	-	-	-	-	-	-
HELMLDPP_00195	7e-286	-	-	-	-	-	-	-	-
HELMLDPP_00196	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HELMLDPP_00197	2.74e-122	-	-	-	-	-	-	-	-
HELMLDPP_00202	1.61e-141	-	-	-	S	-	-	-	KilA-N domain
HELMLDPP_00203	4.96e-59	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
HELMLDPP_00204	1.02e-108	-	-	-	-	-	-	-	-
HELMLDPP_00205	0.0	-	-	-	S	-	-	-	tape measure
HELMLDPP_00207	1.52e-108	-	-	-	-	-	-	-	-
HELMLDPP_00208	7.94e-128	-	-	-	-	-	-	-	-
HELMLDPP_00209	3.26e-88	-	-	-	-	-	-	-	-
HELMLDPP_00211	2.23e-75	-	-	-	-	-	-	-	-
HELMLDPP_00212	1.3e-82	-	-	-	-	-	-	-	-
HELMLDPP_00213	3.36e-291	-	-	-	-	-	-	-	-
HELMLDPP_00214	3.64e-86	-	-	-	-	-	-	-	-
HELMLDPP_00215	7.13e-134	-	-	-	-	-	-	-	-
HELMLDPP_00225	0.0	-	-	-	S	-	-	-	Terminase-like family
HELMLDPP_00228	1.57e-187	-	-	-	-	-	-	-	-
HELMLDPP_00229	8.84e-93	-	-	-	-	-	-	-	-
HELMLDPP_00233	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4 family domain protein
HELMLDPP_00235	1.2e-118	-	-	-	-	-	-	-	-
HELMLDPP_00239	1.72e-213	-	-	-	-	-	-	-	-
HELMLDPP_00240	3.13e-26	-	-	-	-	-	-	-	-
HELMLDPP_00243	9.25e-30	-	-	-	-	-	-	-	-
HELMLDPP_00247	9.68e-313	wzc	-	-	D	ko:K16692	-	ko00000,ko01000,ko01001	protein tyrosine kinase activity
HELMLDPP_00248	5.46e-193	-	-	-	L	-	-	-	Phage integrase family
HELMLDPP_00249	7.65e-272	-	-	-	L	-	-	-	Arm DNA-binding domain
HELMLDPP_00253	2.44e-207	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HELMLDPP_00254	1.48e-141	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HELMLDPP_00255	2.59e-170	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HELMLDPP_00256	1.45e-182	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HELMLDPP_00257	4.73e-146	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HELMLDPP_00258	1.49e-175	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Psort location CytoplasmicMembrane, score 7.88
HELMLDPP_00259	9.47e-317	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HELMLDPP_00260	7.54e-287	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HELMLDPP_00261	2.73e-105	-	-	-	S	-	-	-	COG NOG28134 non supervised orthologous group
HELMLDPP_00262	3.87e-284	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_00263	3.48e-58	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HELMLDPP_00265	1.56e-56	-	-	-	S	-	-	-	Pfam:DUF340
HELMLDPP_00267	2.79e-294	lolE_1	-	-	M	ko:K09808	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
HELMLDPP_00268	3.11e-310	aspC	2.6.1.1, 2.6.1.2, 2.6.1.66	-	E	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I II
HELMLDPP_00269	3.32e-305	-	-	-	G	-	-	-	COG2407 L-fucose isomerase and related
HELMLDPP_00270	2.04e-110	-	-	-	S	-	-	-	COG NOG14445 non supervised orthologous group
HELMLDPP_00271	1.22e-146	yggS	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HELMLDPP_00272	4.63e-227	preA	1.3.98.1	-	F	ko:K00226	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dihydroorotate to orotate
HELMLDPP_00273	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score
HELMLDPP_00274	3.23e-144	-	-	-	S	-	-	-	Peptidase C14 caspase catalytic subunit p20
HELMLDPP_00275	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF3943)
HELMLDPP_00276	7.6e-133	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00277	0.0	-	-	-	E	-	-	-	Peptidase family C69
HELMLDPP_00278	1.18e-295	-	3.4.22.40	-	M	ko:K01372	-	ko00000,ko01000,ko01002	Papain family cysteine protease
HELMLDPP_00279	0.0	-	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HELMLDPP_00280	0.0	-	-	-	S	-	-	-	Capsule assembly protein Wzi
HELMLDPP_00281	9.85e-88	-	-	-	S	-	-	-	Lipocalin-like domain
HELMLDPP_00282	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HELMLDPP_00283	4.9e-208	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00284	0.0	-	-	-	S	-	-	-	COG NOG28036 non supervised orthologous group
HELMLDPP_00285	3.12e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HELMLDPP_00286	1.17e-216	-	-	-	M	-	-	-	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HELMLDPP_00287	7.14e-126	rnfA	-	-	C	ko:K03617	-	ko00000	Part of a membrane complex involved in electron transport
HELMLDPP_00288	9.52e-128	rnfE	-	-	C	ko:K03613	-	ko00000	Part of a membrane complex involved in electron transport
HELMLDPP_00289	2.91e-163	rnfG	-	-	C	ko:K03612	-	ko00000	Part of a membrane complex involved in electron transport
HELMLDPP_00290	6.64e-234	rnfD	-	-	C	ko:K03614	-	ko00000	Part of a membrane complex involved in electron transport
HELMLDPP_00291	0.0	rnfC	-	-	C	ko:K03615	-	ko00000	Part of a membrane complex involved in electron transport
HELMLDPP_00292	8.59e-180	rnfB	-	-	C	ko:K03616	-	ko00000	Ferredoxin
HELMLDPP_00293	1.2e-101	-	-	-	T	ko:K03803	-	ko00000,ko03021	Positive regulator of sigma(E), RseC MucC
HELMLDPP_00294	6.63e-278	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
HELMLDPP_00295	1.69e-204	-	-	-	EG	-	-	-	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HELMLDPP_00296	1.03e-264	-	-	-	P	-	-	-	Transporter, major facilitator family protein
HELMLDPP_00297	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HELMLDPP_00298	2.23e-232	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HELMLDPP_00300	2.27e-188	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HELMLDPP_00301	0.0	-	-	-	E	-	-	-	Transglutaminase-like protein
HELMLDPP_00302	3.66e-168	-	-	-	U	-	-	-	Potassium channel protein
HELMLDPP_00304	0.0	gadC	-	-	E	ko:K20265	ko02024,map02024	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00305	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00306	1.3e-315	nhaA	-	-	P	ko:K03313	-	ko00000,ko02000	) H( ) antiporter that extrudes sodium in exchange for external protons
HELMLDPP_00307	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HELMLDPP_00308	8.98e-86	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00309	1.85e-40	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
HELMLDPP_00310	7.06e-126	-	-	-	S	-	-	-	COG NOG16874 non supervised orthologous group
HELMLDPP_00311	2.9e-227	hprA	1.1.1.29	-	C	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HELMLDPP_00312	1.11e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HELMLDPP_00313	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
HELMLDPP_00314	6.11e-256	-	-	-	S	-	-	-	amine dehydrogenase activity
HELMLDPP_00315	1.05e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HELMLDPP_00316	1.87e-107	-	-	-	L	-	-	-	DNA-binding protein
HELMLDPP_00317	1.49e-10	-	-	-	-	-	-	-	-
HELMLDPP_00318	9.46e-103	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_00320	2.76e-70	-	-	-	-	-	-	-	-
HELMLDPP_00321	0.0	-	3.6.4.12	-	L	ko:K17680	-	ko00000,ko01000,ko03029	Psort location Cytoplasmic, score 8.96
HELMLDPP_00322	3.71e-238	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
HELMLDPP_00323	1.55e-46	-	-	-	-	-	-	-	-
HELMLDPP_00324	3.59e-163	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_00325	9.46e-244	-	-	-	M	-	-	-	Domain of unknown function (DUF1972)
HELMLDPP_00326	1.69e-130	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HELMLDPP_00327	1.05e-91	-	-	-	M	-	-	-	LicD family
HELMLDPP_00328	3.54e-153	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HELMLDPP_00329	0.0	-	-	-	EM	-	-	-	Nucleotidyl transferase
HELMLDPP_00330	1.46e-113	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HELMLDPP_00331	2.05e-52	-	-	-	M	-	-	-	Glycosyl transferase family 2
HELMLDPP_00333	2.17e-07	-	-	-	S	-	-	-	Encoded by
HELMLDPP_00334	9.89e-165	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HELMLDPP_00336	6.33e-46	-	-	-	-	-	-	-	-
HELMLDPP_00337	9.58e-268	-	-	-	K	-	-	-	Participates in transcription elongation, termination and antitermination
HELMLDPP_00338	9.37e-55	-	-	-	S	-	-	-	Protein of unknown function DUF86
HELMLDPP_00339	9.13e-20	-	-	-	S	-	-	-	Protein of unknown function DUF86
HELMLDPP_00340	2.1e-64	-	-	-	S	ko:K07075	-	ko00000	Nucleotidyltransferase domain
HELMLDPP_00341	0.0	-	-	-	M	-	-	-	COG NOG06397 non supervised orthologous group
HELMLDPP_00342	1.81e-158	-	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HELMLDPP_00343	2.14e-179	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HELMLDPP_00344	1.2e-203	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00345	1.18e-274	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HELMLDPP_00346	5.86e-188	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
HELMLDPP_00347	0.0	glnS	6.1.1.18	-	J	ko:K01886	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glutamine--tRNA ligase
HELMLDPP_00348	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00349	1.33e-134	dedA	-	-	S	-	-	-	SNARE associated Golgi protein
HELMLDPP_00350	8.84e-113	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HELMLDPP_00351	8.18e-269	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HELMLDPP_00352	2.11e-266	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HELMLDPP_00353	2.34e-267	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HELMLDPP_00354	0.0	-	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	Psort location CytoplasmicMembrane, score
HELMLDPP_00355	7.31e-214	rmlA	2.7.7.24	-	H	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HELMLDPP_00356	4.11e-140	rfbC	5.1.3.13	-	G	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HELMLDPP_00357	4.45e-255	-	-	-	M	-	-	-	Chain length determinant protein
HELMLDPP_00358	0.0	kpsD	-	-	M	-	-	-	COG1596 Periplasmic protein involved in polysaccharide export
HELMLDPP_00359	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_00360	0.0	xylB_2	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Carbohydrate kinase, FGGY family protein
HELMLDPP_00361	1.23e-186	-	-	-	F	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00362	2.99e-82	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_00363	1.34e-278	-	-	-	M	-	-	-	COG COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HELMLDPP_00364	1.1e-195	-	-	-	MU	-	-	-	COG NOG27134 non supervised orthologous group
HELMLDPP_00365	0.0	-	-	-	M	-	-	-	COG NOG36677 non supervised orthologous group
HELMLDPP_00366	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00367	5.6e-221	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase, group 2 family protein
HELMLDPP_00368	3.74e-265	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HELMLDPP_00369	1.48e-268	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00370	3.09e-137	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 9.26
HELMLDPP_00371	6.45e-202	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HELMLDPP_00372	3.55e-231	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_00373	3.18e-196	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_00374	2.35e-215	-	-	-	-	-	-	-	-
HELMLDPP_00375	2.38e-311	rfbB	-	-	GM	ko:K09691	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HELMLDPP_00376	4.92e-208	-	-	-	GM	ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HELMLDPP_00377	7.04e-291	-	-	-	M	-	-	-	Glycosyltransferase Family 4
HELMLDPP_00378	2.93e-235	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00379	4.59e-247	-	-	-	M	-	-	-	Glycosyltransferase
HELMLDPP_00380	1.4e-284	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_00381	1.35e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_00382	8.07e-282	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00383	1.43e-293	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HELMLDPP_00384	5.34e-195	-	-	-	Q	-	-	-	Methionine biosynthesis protein MetW
HELMLDPP_00385	2.74e-206	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_00386	7.33e-271	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_00387	7.95e-292	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00388	5.07e-43	-	-	-	KT	-	-	-	Response regulator receiver domain
HELMLDPP_00389	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
HELMLDPP_00390	6.86e-255	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family protein
HELMLDPP_00391	2.25e-264	-	2.7.13.3	-	T	ko:K11527	-	ko00000,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HELMLDPP_00392	6.41e-237	-	4.1.1.35	-	GM	ko:K08678	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase dehydratase family
HELMLDPP_00393	3.75e-212	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	COG0351 Hydroxymethylpyrimidine phosphomethylpyrimidine kinase
HELMLDPP_00394	1.88e-230	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
HELMLDPP_00395	1.19e-186	-	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HELMLDPP_00396	0.0	amyA2	-	-	G	-	-	-	Alpha amylase, catalytic domain
HELMLDPP_00397	2.84e-263	hpaIIR	3.1.21.4	-	L	ko:K01155	-	ko00000,ko01000,ko02048	COG NOG26934 non supervised orthologous group
HELMLDPP_00398	7.19e-261	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HELMLDPP_00400	8.09e-137	-	-	-	S	-	-	-	MvaI/BcnI restriction endonuclease family
HELMLDPP_00402	7.63e-63	vsr	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HELMLDPP_00403	3.66e-93	-	-	-	-	-	-	-	-
HELMLDPP_00404	4.54e-230	-	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HELMLDPP_00406	0.000337	-	-	-	S	-	-	-	dextransucrase activity
HELMLDPP_00407	2.02e-33	tolA	-	-	M	ko:K03832	-	ko00000,ko02000	energy transducer activity
HELMLDPP_00408	1.83e-121	-	-	-	L	-	-	-	Phage integrase family
HELMLDPP_00409	5.21e-62	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
HELMLDPP_00410	1.38e-46	-	-	-	-	-	-	-	-
HELMLDPP_00411	8.25e-43	-	-	-	-	-	-	-	-
HELMLDPP_00412	0.0	-	-	-	-	-	-	-	-
HELMLDPP_00413	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00414	2.51e-95	-	-	-	J	-	-	-	Threonine alanine tRNA ligase second additional domain protein
HELMLDPP_00415	2.66e-97	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HELMLDPP_00416	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score 7.88
HELMLDPP_00417	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
HELMLDPP_00418	4.94e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HELMLDPP_00419	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HELMLDPP_00420	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HELMLDPP_00421	0.0	gltB	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Class II glutamine amidotransferase
HELMLDPP_00422	0.0	gltD	1.4.1.13, 1.4.1.14	-	C	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HELMLDPP_00423	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase, glutamine-hydrolyzing
HELMLDPP_00424	3.6e-28	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HELMLDPP_00425	1.03e-198	-	-	-	S	-	-	-	Carboxypeptidase regulatory-like domain
HELMLDPP_00427	0.0	-	-	-	L	-	-	-	helicase
HELMLDPP_00428	8.26e-29	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00429	2.38e-43	vapC	-	-	S	ko:K18828	-	ko00000,ko01000,ko02048,ko03016	PIN domain
HELMLDPP_00430	1.75e-52	-	-	-	-	-	-	-	-
HELMLDPP_00431	2.33e-92	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00432	1.83e-14	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00433	9.31e-107	-	-	-	-	-	-	-	-
HELMLDPP_00434	2.68e-227	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_00435	8.85e-61	-	-	-	-	-	-	-	-
HELMLDPP_00436	6.33e-254	tagO	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00437	4.21e-206	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family 2
HELMLDPP_00438	8.6e-220	-	-	-	H	-	-	-	Core-2/I-Branching enzyme
HELMLDPP_00439	6.28e-272	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HELMLDPP_00440	2.07e-261	-	2.4.1.291	GT4	M	ko:K17248	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HELMLDPP_00441	2.42e-300	-	-	-	S	-	-	-	EpsG family
HELMLDPP_00442	4.88e-197	-	-	-	S	-	-	-	Glycosyl transferase family 2
HELMLDPP_00443	4.42e-312	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_00444	1.58e-238	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HELMLDPP_00445	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HELMLDPP_00447	6.1e-312	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HELMLDPP_00448	2.67e-220	-	-	-	GM	-	-	-	GDP-mannose 4,6 dehydratase
HELMLDPP_00449	2.79e-102	-	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HELMLDPP_00450	1.37e-272	-	4.2.1.45	-	M	ko:K01709	ko00520,map00520	ko00000,ko00001,ko01000	Polysaccharide biosynthesis protein
HELMLDPP_00451	8.45e-194	rfbF	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HELMLDPP_00452	4.47e-206	-	-	-	-	-	-	-	-
HELMLDPP_00453	3.5e-92	-	-	-	-	-	-	-	-
HELMLDPP_00454	2.64e-109	-	-	-	L	-	-	-	TIGRFAM DNA-binding protein, histone-like
HELMLDPP_00455	1.08e-80	-	-	-	L	-	-	-	regulation of translation
HELMLDPP_00457	9.07e-106	-	-	-	V	-	-	-	N-acetylmuramoyl-L-alanine amidase
HELMLDPP_00458	7.23e-200	-	-	-	-	-	-	-	-
HELMLDPP_00459	0.0	-	-	-	Q	-	-	-	depolymerase
HELMLDPP_00460	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	alpha-L-fucosidase
HELMLDPP_00461	2.73e-204	nucA_1	-	-	F	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	Psort location Extracellular, score
HELMLDPP_00462	0.0	abf2	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase domain protein
HELMLDPP_00463	2.38e-230	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HELMLDPP_00464	1.71e-192	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HELMLDPP_00465	1.51e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HELMLDPP_00466	3.13e-38	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HELMLDPP_00467	1.25e-134	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HELMLDPP_00468	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HELMLDPP_00469	1.08e-204	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
HELMLDPP_00470	1.14e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HELMLDPP_00471	2.41e-92	ruvX	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HELMLDPP_00472	2.05e-295	-	-	-	-	-	-	-	-
HELMLDPP_00473	7.92e-42	-	-	-	S	-	-	-	Domain of unknown function (DUF3869)
HELMLDPP_00474	1.43e-233	-	-	-	M	ko:K03286	-	ko00000,ko02000	OmpA family
HELMLDPP_00475	2.33e-238	-	-	-	S	-	-	-	COG NOG26583 non supervised orthologous group
HELMLDPP_00476	1.29e-95	-	-	-	D	-	-	-	Sporulation and cell division repeat protein
HELMLDPP_00477	1.19e-33	-	-	-	S	-	-	-	COG NOG35214 non supervised orthologous group
HELMLDPP_00478	7.42e-68	-	-	-	S	-	-	-	COG NOG30994 non supervised orthologous group
HELMLDPP_00479	4.32e-53	-	-	-	S	-	-	-	COG NOG35393 non supervised orthologous group
HELMLDPP_00480	0.0	-	-	-	M	-	-	-	Tricorn protease homolog
HELMLDPP_00481	0.0	-	-	-	P	ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HELMLDPP_00482	0.0	eptA	-	-	S	-	-	-	lipid A phosphoethanolamine transferase, associated with polymyxin resistance
HELMLDPP_00483	8.34e-300	-	-	-	M	-	-	-	COG NOG06295 non supervised orthologous group
HELMLDPP_00484	5.78e-294	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00485	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_00486	3.54e-246	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_00487	2.34e-203	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HELMLDPP_00488	0.0	-	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HELMLDPP_00489	4.97e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF4891)
HELMLDPP_00490	1.94e-105	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00491	2.45e-23	-	-	-	-	-	-	-	-
HELMLDPP_00492	2.32e-29	-	-	-	S	-	-	-	YtxH-like protein
HELMLDPP_00493	1.74e-294	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HELMLDPP_00494	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I
HELMLDPP_00495	1.04e-141	trpG	2.6.1.85, 4.1.3.27	-	EH	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Glutamine amidotransferase, class I
HELMLDPP_00496	4.89e-237	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HELMLDPP_00497	4.62e-180	trpC	4.1.1.48	-	E	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HELMLDPP_00498	8.84e-152	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HELMLDPP_00499	5.63e-179	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HELMLDPP_00500	6.1e-255	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase, type I
HELMLDPP_00501	4.64e-159	srrA	-	-	K	ko:K07657,ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_00502	0.0	-	2.7.13.3	-	T	ko:K02484,ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00503	2.63e-150	sfp	-	-	H	-	-	-	Belongs to the P-Pant transferase superfamily
HELMLDPP_00504	2.06e-313	gldE	-	-	S	-	-	-	Gliding motility-associated protein GldE
HELMLDPP_00505	1.15e-104	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HELMLDPP_00506	7.5e-263	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG1194 A G-specific DNA glycosylase
HELMLDPP_00507	4.76e-56	hupA	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Belongs to the bacterial histone-like protein family
HELMLDPP_00508	0.0	rng	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	S1 RNA binding domain
HELMLDPP_00509	6.93e-194	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HELMLDPP_00510	3.83e-127	-	-	-	CO	-	-	-	Redoxin family
HELMLDPP_00511	9.27e-140	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00512	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HELMLDPP_00513	2.42e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HELMLDPP_00514	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HELMLDPP_00515	3.04e-176	yfbT	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HELMLDPP_00516	1.49e-314	-	-	-	S	-	-	-	Abhydrolase family
HELMLDPP_00517	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00518	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00519	2.39e-254	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_00520	2.72e-149	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HELMLDPP_00521	1.32e-290	nagC	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_00522	5.03e-230	nanA	4.1.3.3, 4.2.1.41, 4.3.3.7	-	EM	ko:K01639,ko:K01707,ko:K01714	ko00053,ko00261,ko00300,ko00520,ko01100,ko01110,ko01120,ko01130,ko01230,map00053,map00261,map00300,map00520,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapA family
HELMLDPP_00523	8.77e-308	nanE	5.1.3.8	-	G	ko:K01787	ko00520,map00520	ko00000,ko00001,ko01000	COG COG2942 N-acyl-D-glucosamine 2-epimerase
HELMLDPP_00524	1.51e-301	-	-	-	G	ko:K08191	-	ko00000,ko02000	Transporter, major facilitator family protein
HELMLDPP_00525	6.41e-192	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HELMLDPP_00526	0.0	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_00527	9.44e-185	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00528	1.07e-209	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HELMLDPP_00529	1.81e-251	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_00530	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_00531	2.28e-308	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00532	5.44e-165	-	-	-	L	-	-	-	Bacterial DNA-binding protein
HELMLDPP_00533	2.23e-155	-	-	-	-	-	-	-	-
HELMLDPP_00534	4.7e-37	-	-	-	-	-	-	-	-
HELMLDPP_00535	2.95e-211	-	-	-	-	-	-	-	-
HELMLDPP_00536	5.05e-161	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HELMLDPP_00537	0.0	-	-	-	P	-	-	-	CarboxypepD_reg-like domain
HELMLDPP_00538	5.78e-212	-	-	-	S	-	-	-	Protein of unknown function (Porph_ging)
HELMLDPP_00539	0.0	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	histidine kinase DNA gyrase B
HELMLDPP_00540	2.9e-146	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_00541	1.5e-315	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HELMLDPP_00542	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_00543	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HELMLDPP_00544	0.0	nagZ3	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HELMLDPP_00545	4.47e-278	-	-	-	S	-	-	-	Cyclically-permuted mutarotase family protein
HELMLDPP_00546	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HELMLDPP_00547	0.0	-	3.2.1.25	-	G	ko:K01192	ko00511,ko04142,map00511,map04142	ko00000,ko00001,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HELMLDPP_00548	0.0	estS	3.1.1.53	-	E	ko:K05970	-	ko00000,ko01000	Carbohydrate esterase, sialic acid-specific acetylesterase
HELMLDPP_00549	1.02e-158	estA	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HELMLDPP_00550	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 20, catalytic domain
HELMLDPP_00551	0.0	nanH	3.2.1.18	GH33	G	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	ko00000,ko00001,ko01000,ko02042	BNR Asp-box repeat protein
HELMLDPP_00552	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_00553	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00555	2.5e-258	asnA	6.3.1.1	-	E	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 10.00
HELMLDPP_00556	3.19e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HELMLDPP_00557	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score 9.49
HELMLDPP_00558	3.7e-133	-	-	-	H	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_00559	1.36e-289	-	-	-	S	-	-	-	protein conserved in bacteria
HELMLDPP_00560	2.93e-112	-	-	-	U	-	-	-	Peptidase S24-like
HELMLDPP_00561	5.69e-236	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00562	0.0	-	-	-	V	ko:K06148	-	ko00000,ko02000	ATPases associated with a variety of cellular activities
HELMLDPP_00563	2.94e-255	-	-	-	S	-	-	-	Uncharacterised nucleotidyltransferase
HELMLDPP_00564	2.11e-34	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HELMLDPP_00565	0.0	-	-	-	-	-	-	-	-
HELMLDPP_00566	5.12e-06	-	-	-	-	-	-	-	-
HELMLDPP_00569	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00570	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00571	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF1566)
HELMLDPP_00572	0.0	lacZ_17	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_00574	1.47e-138	qacR	-	-	K	-	-	-	transcriptional regulator, TetR family
HELMLDPP_00575	8.6e-169	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	with different specificities (related to short-chain alcohol
HELMLDPP_00576	2.23e-163	rluC	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	ribosomal pseudouridine synthase C, large subunit
HELMLDPP_00577	2.14e-59	-	-	-	S	-	-	-	COG NOG30576 non supervised orthologous group
HELMLDPP_00578	0.0	-	-	-	T	ko:K07713	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HELMLDPP_00579	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00580	4.61e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
HELMLDPP_00581	1.47e-305	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Peptidase M16 inactive domain protein
HELMLDPP_00582	2.15e-199	-	5.2.1.8	-	M	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HELMLDPP_00583	2.81e-233	-	-	-	C	ko:K07138	-	ko00000	Fe-S center protein
HELMLDPP_00584	0.0	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_00585	6.08e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF1893)
HELMLDPP_00586	1.71e-203	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	protein contains double-stranded beta-helix domain
HELMLDPP_00588	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
HELMLDPP_00589	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
HELMLDPP_00590	6.83e-223	-	-	-	JM	-	-	-	COG NOG09722 non supervised orthologous group
HELMLDPP_00591	6.5e-215	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_00592	7.67e-152	-	-	-	S	ko:K06973	-	ko00000	neutral zinc metallopeptidase
HELMLDPP_00593	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 63 C-terminal domain
HELMLDPP_00594	1.4e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_00595	9.9e-240	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_00596	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00597	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00598	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00599	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
HELMLDPP_00600	1.64e-142	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HELMLDPP_00601	3.1e-168	-	-	-	K	ko:K02081	-	ko00000,ko03000	DeoR C terminal sensor domain
HELMLDPP_00602	7.82e-202	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	XFP N-terminal domain
HELMLDPP_00603	5.6e-222	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HELMLDPP_00604	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HELMLDPP_00605	0.0	-	-	-	G	-	-	-	L-fucose isomerase, C-terminal domain
HELMLDPP_00606	9.02e-232	-	-	-	G	ko:K05340	-	ko00000,ko02000	COG NOG04879 non supervised orthologous group
HELMLDPP_00607	2.29e-185	-	-	-	G	ko:K10439,ko:K17213	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein domain
HELMLDPP_00608	2.24e-200	-	-	-	G	-	-	-	Protein of unknown function (DUF1593)
HELMLDPP_00609	0.0	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HELMLDPP_00610	3.06e-282	hydF	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00611	0.0	hydG	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Iron-only hydrogenase maturation rSAM protein HydG
HELMLDPP_00612	5.22e-255	hydE	2.8.1.6	-	C	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Iron-only hydrogenase maturation rSAM protein HydE
HELMLDPP_00613	0.0	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HELMLDPP_00614	9.28e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HELMLDPP_00615	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HELMLDPP_00617	6.43e-300	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HELMLDPP_00618	2.02e-138	-	-	-	T	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
HELMLDPP_00619	2.05e-126	cah	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HELMLDPP_00620	0.0	-	-	-	S	-	-	-	Oxidoreductase NAD-binding domain protein
HELMLDPP_00621	1.9e-230	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_00622	2.83e-172	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase like
HELMLDPP_00623	8.16e-148	-	-	-	S	-	-	-	DJ-1/PfpI family
HELMLDPP_00624	1.56e-103	-	-	-	-	-	-	-	-
HELMLDPP_00625	0.0	-	-	-	D	-	-	-	Domain of unknown function
HELMLDPP_00627	5.19e-275	-	-	-	S	-	-	-	Clostripain family
HELMLDPP_00628	0.0	-	-	-	D	ko:K21449	-	ko00000,ko02000	nuclear chromosome segregation
HELMLDPP_00630	1.33e-126	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HELMLDPP_00632	1.02e-131	-	-	-	L	-	-	-	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs
HELMLDPP_00633	7.26e-286	accC	6.3.4.14, 6.4.1.2, 6.4.1.3	-	I	ko:K01961,ko:K01965	ko00061,ko00280,ko00620,ko00630,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HELMLDPP_00634	6.15e-90	-	6.4.1.1	-	I	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Biotin-requiring enzyme
HELMLDPP_00636	0.0	-	-	-	T	-	-	-	Two component regulator propeller
HELMLDPP_00637	0.0	-	-	-	T	-	-	-	Two component regulator propeller
HELMLDPP_00638	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
HELMLDPP_00639	1.93e-266	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00640	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00641	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00642	4.49e-191	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	COG0584 Glycerophosphoryl diester phosphodiesterase
HELMLDPP_00643	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HELMLDPP_00644	8.76e-315	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_00645	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HELMLDPP_00646	0.0	-	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 2)
HELMLDPP_00647	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00648	0.0	-	-	-	-	-	-	-	-
HELMLDPP_00649	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00650	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_00651	0.0	-	-	-	M	-	-	-	COG NOG07608 non supervised orthologous group
HELMLDPP_00652	0.0	-	-	-	M	-	-	-	COG NOG07608 non supervised orthologous group
HELMLDPP_00653	3.43e-237	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score 9.97
HELMLDPP_00654	0.0	ahpF	-	-	C	ko:K03387	-	ko00000,ko01000	alkyl hydroperoxide reductase subunit F
HELMLDPP_00655	3.51e-136	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Psort location Cytoplasmic, score
HELMLDPP_00656	2.76e-307	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HELMLDPP_00657	4.96e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
HELMLDPP_00658	4.3e-299	piuB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00659	0.0	-	-	-	E	-	-	-	Domain of unknown function (DUF4374)
HELMLDPP_00660	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00661	0.0	-	-	-	G	-	-	-	Beta galactosidase small chain
HELMLDPP_00662	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HELMLDPP_00663	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00664	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00665	0.0	-	-	-	T	-	-	-	Two component regulator propeller
HELMLDPP_00666	8.9e-51	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00667	0.0	-	-	-	S	ko:K09955	-	ko00000	Domain of unknown function
HELMLDPP_00668	6.84e-260	-	-	-	G	-	-	-	Glycosyl hydrolases family 32 N-terminal domain
HELMLDPP_00669	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
HELMLDPP_00670	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
HELMLDPP_00671	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HELMLDPP_00672	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
HELMLDPP_00673	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_00674	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00675	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00676	2.06e-05	-	-	-	-	-	-	-	-
HELMLDPP_00677	6.69e-111	-	-	-	L	ko:K07497	-	ko00000	transposition
HELMLDPP_00678	6.09e-79	-	3.6.1.3	-	S	ko:K07132	-	ko00000,ko01000	AAA domain
HELMLDPP_00683	3.34e-58	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
HELMLDPP_00684	8.36e-137	-	-	-	-	-	-	-	-
HELMLDPP_00685	4.06e-31	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00686	1.02e-178	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00687	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00688	7.22e-143	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG COG2818 3-methyladenine DNA glycosylase
HELMLDPP_00689	4.24e-48	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00692	6.98e-241	gpr	-	-	C	ko:K19265	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HELMLDPP_00693	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
HELMLDPP_00694	6.49e-90	-	-	-	S	-	-	-	Polyketide cyclase
HELMLDPP_00695	5.07e-150	pyrE	2.4.2.10, 4.1.1.23	-	F	ko:K00762,ko:K13421	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HELMLDPP_00696	6.65e-171	comF	2.4.2.14	-	S	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	ComF family
HELMLDPP_00697	9.32e-112	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HELMLDPP_00698	1.7e-199	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HELMLDPP_00699	4.7e-263	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HELMLDPP_00700	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
HELMLDPP_00701	9.41e-175	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HELMLDPP_00702	0.0	yaeT	-	-	M	ko:K07277	-	ko00000,ko02000,ko03029	Outer membrane protein assembly complex, YaeT protein
HELMLDPP_00703	4.82e-103	ompH	-	-	M	ko:K06142	-	ko00000	membrane
HELMLDPP_00704	2.53e-87	ompH	-	-	M	ko:K06142	-	ko00000	membrane
HELMLDPP_00705	8.26e-204	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HELMLDPP_00706	3.49e-214	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Pyridoxal kinase
HELMLDPP_00707	1.85e-282	lolE	-	-	M	ko:K09808,ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4591 ABC-type transport system, involved in lipoprotein release, permease component
HELMLDPP_00708	6.56e-70	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HELMLDPP_00709	9.51e-155	mdmC	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_00710	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Pyruvate kinase
HELMLDPP_00711	3.42e-97	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HELMLDPP_00712	1.08e-217	xerC	-	-	D	ko:K04763	-	ko00000,ko03036	Tyrosine recombinase XerC
HELMLDPP_00713	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_00714	1.73e-249	-	-	-	CO	-	-	-	AhpC TSA family
HELMLDPP_00715	0.0	comM	-	-	O	ko:K07391	-	ko00000	Magnesium chelatase, subunit ChlI
HELMLDPP_00717	4.43e-115	-	-	-	-	-	-	-	-
HELMLDPP_00718	2.79e-112	-	-	-	-	-	-	-	-
HELMLDPP_00719	1.01e-280	-	-	-	C	-	-	-	radical SAM domain protein
HELMLDPP_00720	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HELMLDPP_00721	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00722	5.13e-244	-	-	-	S	-	-	-	Acyltransferase family
HELMLDPP_00723	4.88e-198	-	-	-	-	-	-	-	-
HELMLDPP_00724	0.0	ispD	1.1.1.405, 2.7.7.40, 2.7.7.60	-	M	ko:K00991,ko:K21681	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HELMLDPP_00725	1.25e-202	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HELMLDPP_00726	2.3e-259	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00727	2.8e-279	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_00728	9.9e-316	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HELMLDPP_00729	2.55e-184	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_00730	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00731	7.76e-168	mtnN	3.2.2.9	-	F	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HELMLDPP_00732	4.45e-119	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HELMLDPP_00733	2.39e-55	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HELMLDPP_00734	5.46e-233	-	-	-	CO	-	-	-	COG NOG24939 non supervised orthologous group
HELMLDPP_00735	2.48e-62	-	-	-	-	-	-	-	-
HELMLDPP_00736	2.06e-60	-	-	-	-	-	-	-	-
HELMLDPP_00737	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4906)
HELMLDPP_00738	4.43e-271	-	-	-	-	-	-	-	-
HELMLDPP_00739	1.96e-253	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HELMLDPP_00740	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HELMLDPP_00741	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HELMLDPP_00742	2.47e-141	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_00743	1.07e-141	-	-	-	S	-	-	-	Domain of unknown function (DUF5033)
HELMLDPP_00744	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HELMLDPP_00745	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HELMLDPP_00746	3.06e-150	-	-	-	C	-	-	-	Nitroreductase family
HELMLDPP_00747	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HELMLDPP_00748	9.82e-156	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	uracil phosphoribosyltransferase
HELMLDPP_00749	2.47e-252	oorB	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HELMLDPP_00750	0.0	porA	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid acceptor oxidoreductase, alpha subunit
HELMLDPP_00752	1.93e-285	kbl	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA
HELMLDPP_00753	2.23e-235	ltd	-	-	M	-	-	-	NAD dependent epimerase dehydratase family
HELMLDPP_00754	3.29e-258	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HELMLDPP_00755	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HELMLDPP_00756	0.0	dcp	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
HELMLDPP_00757	7.09e-244	-	-	-	L	-	-	-	Endonuclease Exonuclease phosphatase family
HELMLDPP_00758	1.93e-210	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00759	3.7e-163	-	3.4.21.105	-	S	ko:K09650	-	ko00000,ko01000,ko01002,ko03029	Psort location CytoplasmicMembrane, score
HELMLDPP_00760	9.69e-51	hupB	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HELMLDPP_00761	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HELMLDPP_00762	8.76e-202	-	-	-	S	-	-	-	COG3943 Virulence protein
HELMLDPP_00763	1.92e-252	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HELMLDPP_00764	0.0	arsA	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_00765	0.0	-	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Carbohydrate binding domain protein
HELMLDPP_00766	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_00767	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
HELMLDPP_00768	0.0	-	-	-	G	-	-	-	COG NOG26813 non supervised orthologous group
HELMLDPP_00769	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HELMLDPP_00770	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00771	0.0	-	-	-	-	-	-	-	-
HELMLDPP_00772	0.0	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Glycosyl hydrolases family 43
HELMLDPP_00773	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HELMLDPP_00774	0.0	hutH	4.3.1.23, 4.3.1.3	-	E	ko:K01745,ko:K10774	ko00340,ko00350,ko01100,map00340,map00350,map01100	ko00000,ko00001,ko00002,ko01000	Aromatic amino acid lyase
HELMLDPP_00775	2.69e-169	fabG3	1.1.1.100, 1.1.1.36	-	IQ	ko:K00023,ko:K00059	ko00061,ko00333,ko00630,ko00650,ko00780,ko01040,ko01100,ko01120,ko01130,ko01200,ko01212,map00061,map00333,map00630,map00650,map00780,map01040,map01100,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HELMLDPP_00776	3.13e-293	fabB	2.3.1.41	-	IQ	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the beta-ketoacyl-ACP synthases family
HELMLDPP_00777	2.39e-50	acpP_2	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HELMLDPP_00778	1.22e-216	-	-	-	S	-	-	-	Bacterial lipid A biosynthesis acyltransferase
HELMLDPP_00779	2.82e-260	crtF	-	-	Q	-	-	-	O-methyltransferase
HELMLDPP_00780	3.12e-100	-	-	-	I	-	-	-	dehydratase
HELMLDPP_00781	6.51e-103	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HELMLDPP_00782	0.0	fabF2	2.3.1.41	-	IQ	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the beta-ketoacyl-ACP synthases family
HELMLDPP_00783	4.77e-51	acpP2	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HELMLDPP_00784	1.07e-282	fabF2	2.3.1.41	-	IQ	ko:K00647	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the beta-ketoacyl-ACP synthases family
HELMLDPP_00785	1.09e-226	-	-	-	IQ	-	-	-	Beta-ketoacyl synthase, N-terminal domain
HELMLDPP_00786	5.54e-208	-	-	-	S	-	-	-	KilA-N domain
HELMLDPP_00787	3.15e-162	pgdA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HELMLDPP_00788	6.61e-141	-	-	-	M	-	-	-	Outer membrane lipoprotein carrier protein LolA
HELMLDPP_00789	4.13e-122	-	-	-	-	-	-	-	-
HELMLDPP_00790	3.26e-88	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HELMLDPP_00791	1.49e-150	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HELMLDPP_00792	4.83e-64	-	-	-	-	-	-	-	-
HELMLDPP_00793	1.18e-294	-	-	-	S	-	-	-	Domain of unknown function (DUF4221)
HELMLDPP_00794	9.63e-291	-	-	-	M	-	-	-	Uncharacterized protein conserved in bacteria (DUF2062)
HELMLDPP_00795	0.0	-	-	-	I	ko:K07003	-	ko00000	Phosphate acyltransferases
HELMLDPP_00796	0.0	crtI	-	-	Q	-	-	-	Flavin containing amine oxidoreductase
HELMLDPP_00797	0.0	-	-	-	M	-	-	-	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase
HELMLDPP_00798	0.0	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	AMP-binding enzyme
HELMLDPP_00799	2.87e-132	-	-	-	-	-	-	-	-
HELMLDPP_00800	0.0	-	-	-	T	-	-	-	PAS domain
HELMLDPP_00801	1.1e-188	-	-	-	-	-	-	-	-
HELMLDPP_00802	5.49e-196	-	-	-	S	-	-	-	Protein of unknown function (DUF3108)
HELMLDPP_00803	0.0	-	-	-	S	-	-	-	COG NOG07965 non supervised orthologous group
HELMLDPP_00804	0.0	-	-	-	H	-	-	-	GH3 auxin-responsive promoter
HELMLDPP_00805	4.06e-243	pfkA	2.7.1.11, 2.7.1.90	-	F	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HELMLDPP_00806	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HELMLDPP_00807	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00808	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_00809	1.26e-182	-	-	-	M	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
HELMLDPP_00810	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_00811	0.0	-	-	-	G	-	-	-	Alpha-L-fucosidase
HELMLDPP_00812	0.0	-	-	-	G	-	-	-	Raffinose synthase or seed imbibition protein Sip1
HELMLDPP_00813	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_00814	3.32e-212	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HELMLDPP_00815	1.21e-303	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HELMLDPP_00816	1.5e-44	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HELMLDPP_00817	4.58e-134	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HELMLDPP_00818	1.14e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_00819	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00820	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_00821	4.79e-220	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_00822	4.28e-224	-	-	-	S	-	-	-	Domain of unknown function (DUF5119)
HELMLDPP_00823	3.2e-301	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_00824	2.94e-236	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_00825	0.0	-	-	-	-	-	-	-	-
HELMLDPP_00826	1.85e-115	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily K00960
HELMLDPP_00827	5.05e-191	-	-	-	PT	-	-	-	COG COG3712 Fe2 -dicitrate sensor, membrane component
HELMLDPP_00828	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HELMLDPP_00829	3.56e-234	-	-	-	S	-	-	-	Domain of unknown function (DUF4249)
HELMLDPP_00831	3.01e-252	pdxB	1.1.1.290	-	H	ko:K03473	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate
HELMLDPP_00832	2.89e-251	-	-	GT9	M	ko:K02843	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Glycosyltransferase family 9
HELMLDPP_00833	4.67e-232	waaM	2.3.1.241	-	M	ko:K02517	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Lipid A biosynthesis (KDO)2-(Lauroyl)-lipid IVA acyltransferase
HELMLDPP_00834	5.65e-282	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HELMLDPP_00835	8.1e-178	-	-	-	S	-	-	-	Glycosyl transferase, family 2
HELMLDPP_00836	4.17e-186	-	-	-	T	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00837	8.64e-224	-	-	-	S	-	-	-	Glycosyl transferase family group 2
HELMLDPP_00838	2.48e-225	-	-	-	M	-	-	-	Glycosyltransferase family 92
HELMLDPP_00839	1.23e-222	-	-	-	S	-	-	-	Core-2/I-Branching enzyme
HELMLDPP_00840	1.35e-283	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_00841	1.45e-232	-	-	-	S	-	-	-	Glycosyl transferase family 2
HELMLDPP_00842	0.0	msbA	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HELMLDPP_00844	7.85e-241	-	-	-	M	-	-	-	Glycosyl transferase family 2
HELMLDPP_00845	0.0	-	-	-	M	-	-	-	COG1368 Phosphoglycerol transferase and related
HELMLDPP_00846	1.77e-228	-	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase, group 2 family protein
HELMLDPP_00847	1.78e-71	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_00848	0.0	arnT	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00849	0.0	ltaS2	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00850	2.08e-156	rnhA	3.1.26.4	-	C	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	double-stranded RNA RNA-DNA hybrid binding protein
HELMLDPP_00851	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Psort location Cytoplasmic, score
HELMLDPP_00852	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00853	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	COG NOG25454 non supervised orthologous group
HELMLDPP_00854	3.58e-300	prtC	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HELMLDPP_00855	7.86e-242	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HELMLDPP_00856	3.27e-121	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HELMLDPP_00857	8.07e-233	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00858	9.48e-264	dfrA	1.1.1.219	-	M	ko:K00091	-	ko00000,ko01000	NAD(P)H-binding
HELMLDPP_00859	4.57e-217	fieF	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HELMLDPP_00860	0.0	rnr	-	-	J	ko:K12573,ko:K12585	ko03018,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HELMLDPP_00861	1.86e-14	-	-	-	-	-	-	-	-
HELMLDPP_00862	3e-221	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
HELMLDPP_00863	6.34e-24	-	-	-	T	-	-	-	histidine kinase DNA gyrase B
HELMLDPP_00864	7.34e-54	-	-	-	T	-	-	-	protein histidine kinase activity
HELMLDPP_00865	3.4e-108	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HELMLDPP_00866	3.93e-220	oxyR	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	Psort location Cytoplasmic, score 9.97
HELMLDPP_00867	6.69e-39	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00869	0.0	rlmL	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HELMLDPP_00870	0.0	pepX2	3.4.14.5	-	E	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
HELMLDPP_00871	1.36e-305	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HELMLDPP_00872	7.97e-194	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00873	1.57e-107	yqaA	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_00874	9.46e-167	mnmC	-	-	S	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_00875	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HELMLDPP_00876	3.77e-113	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_00878	4.61e-220	mntA	-	-	P	ko:K09815,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin
HELMLDPP_00879	2.61e-187	znuC	-	-	P	ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_00880	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00881	6.75e-155	pgdA_1	-	-	G	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_00882	0.0	-	-	-	S	-	-	-	protein conserved in bacteria
HELMLDPP_00883	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HELMLDPP_00884	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG26302 non supervised orthologous group
HELMLDPP_00885	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_00886	7.06e-294	-	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	COG NOG24911 non supervised orthologous group
HELMLDPP_00887	1.29e-193	idnO	1.1.1.69	-	IQ	ko:K00046	-	ko00000,ko01000	Oxidoreductase, short chain dehydrogenase reductase family protein
HELMLDPP_00888	6e-210	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HELMLDPP_00889	0.0	dacB	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4)
HELMLDPP_00890	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3)
HELMLDPP_00891	5.29e-95	-	-	-	S	-	-	-	Bacterial PH domain
HELMLDPP_00892	9.89e-86	-	-	-	S	-	-	-	COG NOG29403 non supervised orthologous group
HELMLDPP_00893	9.24e-122	-	-	-	S	-	-	-	ORF6N domain
HELMLDPP_00894	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HELMLDPP_00895	0.0	-	-	-	G	-	-	-	Protein of unknown function (DUF1593)
HELMLDPP_00896	0.0	pelA	3.1.1.11	-	G	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	pectate lyase
HELMLDPP_00897	0.0	-	-	-	E	-	-	-	Dipeptidyl peptidase IV (DPP IV) N-terminal region
HELMLDPP_00898	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
HELMLDPP_00899	0.0	-	-	-	G	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HELMLDPP_00900	0.0	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HELMLDPP_00901	0.0	-	-	-	JM	-	-	-	N-acetylglucosamine-1-phosphate uridyltransferase
HELMLDPP_00902	2.01e-241	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_00903	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HELMLDPP_00904	1.32e-133	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00905	6.93e-47	-	-	-	S	-	-	-	Domain of unknown function (DUF4133)
HELMLDPP_00907	6.13e-129	-	-	-	-	-	-	-	-
HELMLDPP_00909	3.33e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF3408)
HELMLDPP_00910	3.47e-133	-	-	-	D	-	-	-	ATPase MipZ
HELMLDPP_00911	2.5e-47	-	-	-	-	-	-	-	-
HELMLDPP_00912	6.94e-210	-	-	-	S	-	-	-	Putative amidoligase enzyme
HELMLDPP_00914	3.77e-80	-	-	-	S	ko:K07001	-	ko00000	Phospholipase
HELMLDPP_00915	3.28e-302	-	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Peptidase family M41
HELMLDPP_00916	5.32e-155	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00917	1.73e-89	-	-	-	S	-	-	-	Toxin-antitoxin system, toxin component, Fic family
HELMLDPP_00918	1.83e-249	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HELMLDPP_00919	1.76e-77	pncA	3.5.1.19	-	Q	ko:K08281	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Isochorismatase family
HELMLDPP_00920	1.18e-53	-	-	-	S	ko:K06950	-	ko00000	mRNA catabolic process
HELMLDPP_00921	1.79e-110	-	-	-	K	-	-	-	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HELMLDPP_00922	1.52e-35	-	-	-	-	-	-	-	-
HELMLDPP_00923	6.32e-47	-	-	-	-	-	-	-	-
HELMLDPP_00924	1.41e-123	-	-	-	L	-	-	-	COG NOG14720 non supervised orthologous group
HELMLDPP_00925	3.19e-25	-	-	-	S	-	-	-	KilA-N domain
HELMLDPP_00926	2.45e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HELMLDPP_00930	4.57e-304	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_00931	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC K07714
HELMLDPP_00932	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00933	5.34e-308	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HELMLDPP_00934	3.42e-297	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HELMLDPP_00935	2.28e-309	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_00936	1.29e-296	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00937	2.34e-303	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_00938	4.04e-302	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_00939	1.18e-311	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HELMLDPP_00940	1.48e-306	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system permease component
HELMLDPP_00941	2.9e-150	ytrE_3	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 7.88
HELMLDPP_00942	2.33e-282	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HELMLDPP_00943	4.29e-226	lytG	-	-	MNU	-	-	-	COG1705 Muramidase (flagellum-specific)
HELMLDPP_00944	1.65e-160	-	-	-	T	-	-	-	COG NOG17272 non supervised orthologous group
HELMLDPP_00945	2.19e-118	-	-	-	-	-	-	-	-
HELMLDPP_00946	1.22e-76	-	-	-	-	-	-	-	-
HELMLDPP_00947	4.49e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_00948	1.69e-158	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
HELMLDPP_00949	1.25e-141	-	-	-	J	-	-	-	Domain of unknown function (DUF4476)
HELMLDPP_00950	4.7e-68	-	-	-	S	-	-	-	Belongs to the UPF0145 family
HELMLDPP_00951	2.34e-111	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HELMLDPP_00952	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HELMLDPP_00953	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HELMLDPP_00954	5.61e-103	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HELMLDPP_00955	6.24e-252	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HELMLDPP_00956	7.41e-313	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Folylpolyglutamate synthase
HELMLDPP_00957	1.05e-275	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HELMLDPP_00958	0.0	gluP	-	-	G	ko:K02429	-	ko00000,ko02000	Transporter, major facilitator family protein
HELMLDPP_00959	2.94e-283	galK	2.7.1.6	-	H	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GHMP kinase family. GalK subfamily
HELMLDPP_00960	1.4e-284	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HELMLDPP_00961	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HELMLDPP_00962	1.29e-163	-	-	-	F	-	-	-	Hydrolase, NUDIX family
HELMLDPP_00963	2.33e-182	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HELMLDPP_00964	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HELMLDPP_00965	0.0	araB	-	-	G	-	-	-	Carbohydrate kinase, FGGY family protein
HELMLDPP_00966	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the transketolase family
HELMLDPP_00967	3.25e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HELMLDPP_00968	3.74e-265	-	-	-	S	ko:K03646	-	ko00000,ko02000	Domain of unknown function (DUF4468) with TBP-like fold
HELMLDPP_00970	4.55e-64	-	-	-	O	-	-	-	Tetratricopeptide repeat
HELMLDPP_00971	9.96e-40	oorD	1.2.7.3	-	C	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	4Fe-4S binding domain protein
HELMLDPP_00972	5.87e-255	vorB	1.2.7.11, 1.2.7.3	-	C	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HELMLDPP_00973	1.06e-25	-	-	-	-	-	-	-	-
HELMLDPP_00974	4.35e-190	vorA	1.2.7.11, 1.2.7.3	-	C	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
HELMLDPP_00975	3.68e-125	porG	1.2.7.3	-	C	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	br01601,ko00000,ko00001,ko00002,ko01000	2-oxoacid ferredoxin flavodoxin oxidoreductase, gamma subunit
HELMLDPP_00976	0.0	-	-	-	H	-	-	-	COG NOG07963 non supervised orthologous group
HELMLDPP_00977	1.91e-193	-	-	-	ET	-	-	-	COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain
HELMLDPP_00978	1.95e-251	-	-	-	S	-	-	-	Oxidoreductase, NAD-binding domain protein
HELMLDPP_00979	4.66e-280	-	-	-	N	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00981	5.4e-197	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HELMLDPP_00982	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00983	4.88e-190	-	-	-	S	-	-	-	Psort location OuterMembrane, score
HELMLDPP_00984	5.73e-149	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00986	0.0	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HELMLDPP_00987	2.83e-57	-	-	-	CO	-	-	-	Glutaredoxin
HELMLDPP_00988	7.27e-207	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HELMLDPP_00989	4.58e-82	yccF	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_00990	4.07e-212	acm	-	-	M	ko:K07273	-	ko00000	phage tail component domain protein
HELMLDPP_00991	0.0	pfp	2.7.1.11, 2.7.1.90	-	H	ko:K00895,ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions
HELMLDPP_00992	1.06e-48	-	-	-	S	-	-	-	COG NOG23371 non supervised orthologous group
HELMLDPP_00993	4.13e-138	-	-	-	I	-	-	-	Acyltransferase
HELMLDPP_00994	0.0	glaB	-	-	M	-	-	-	Alpha-galactosidase. Removes both branched alpha-1,3- linked galactose residues of blood group B antigens and linear alpha-1,3-linked galactose structures
HELMLDPP_00995	0.0	xly	-	-	M	-	-	-	fibronectin type III domain protein
HELMLDPP_00996	5.09e-69	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00997	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_00998	0.0	hppA	3.6.1.1	-	C	ko:K15987	ko00190,map00190	ko00000,ko00001,ko01000	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane
HELMLDPP_00999	9.11e-92	-	-	-	S	-	-	-	ACT domain protein
HELMLDPP_01000	9.94e-309	-	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HELMLDPP_01001	1.53e-315	alaC	-	-	E	-	-	-	Aminotransferase, class I II
HELMLDPP_01002	1.42e-133	iorB	1.2.7.8	-	C	ko:K00180	-	br01601,ko00000,ko01000	COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin
HELMLDPP_01003	0.0	iorA	1.2.7.8	-	C	ko:K00179	-	br01601,ko00000,ko01000	Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
HELMLDPP_01004	9.87e-191	yafV	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
HELMLDPP_01005	0.0	-	-	-	L	-	-	-	helicase
HELMLDPP_01006	9.78e-11	-	-	-	S	-	-	-	InterPro IPR018631 IPR012547
HELMLDPP_01007	7.44e-190	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_01008	6.88e-170	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Belongs to the glycosyltransferase 26 family
HELMLDPP_01009	1.15e-42	-	-	-	-	-	-	-	-
HELMLDPP_01010	0.000127	-	-	-	M	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_01011	3e-35	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_01013	8.91e-72	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_01014	2.37e-57	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_01015	1.74e-137	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HELMLDPP_01017	3.73e-210	-	-	-	-	-	-	-	-
HELMLDPP_01018	0.0	-	3.6.4.12	-	L	ko:K17680	-	ko00000,ko01000,ko03029	Psort location Cytoplasmic, score 8.96
HELMLDPP_01019	2.56e-50	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HELMLDPP_01020	2.47e-96	-	-	-	L	-	-	-	DNA-binding domain
HELMLDPP_01022	1.35e-97	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HELMLDPP_01023	1.62e-66	-	-	-	-	-	-	-	-
HELMLDPP_01024	5.24e-110	ytbE	-	-	S	-	-	-	aldo keto reductase family
HELMLDPP_01026	6.19e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01028	6.34e-198	-	-	-	C	-	-	-	4Fe-4S binding domain protein
HELMLDPP_01029	1.38e-161	-	6.2.1.3	-	IQ	ko:K01897,ko:K18660	ko00061,ko00071,ko00280,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map00280,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HELMLDPP_01030	1.13e-06	-	-	-	IQ	ko:K02078	-	ko00000,ko00001	Phosphopantetheine attachment site
HELMLDPP_01031	1.57e-194	-	-	-	-	-	-	-	-
HELMLDPP_01032	1.56e-136	-	-	-	M	ko:K03832	-	ko00000,ko02000	Gram-negative bacterial TonB protein C-terminal
HELMLDPP_01033	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HELMLDPP_01034	2.77e-293	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01035	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_01036	3.87e-198	-	-	-	-	-	-	-	-
HELMLDPP_01037	0.0	aspT	-	-	S	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01038	0.0	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	COG COG0436 Aspartate tyrosine aromatic aminotransferase
HELMLDPP_01039	0.0	-	-	-	M	-	-	-	peptidase S41
HELMLDPP_01040	2.1e-104	-	-	-	MP	ko:K06079	ko01503,map01503	ko00000,ko00001	COG NOG29769 non supervised orthologous group
HELMLDPP_01041	2.13e-142	-	-	-	S	-	-	-	Domain of unknown function (DUF4136)
HELMLDPP_01042	1.65e-153	-	-	-	M	-	-	-	COG NOG27406 non supervised orthologous group
HELMLDPP_01043	3.05e-183	dpm1	2.4.1.83	GT2	S	ko:K00721	ko00510,ko01100,map00510,map01100	ko00000,ko00001,ko01000,ko01003	b-glycosyltransferase, glycosyltransferase family 2 protein
HELMLDPP_01044	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01045	3.77e-216	metH_2	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain
HELMLDPP_01046	4.01e-282	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
HELMLDPP_01047	1.57e-182	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HELMLDPP_01048	4.28e-153	-	-	-	S	-	-	-	COG NOG27017 non supervised orthologous group
HELMLDPP_01049	0.0	dpp11	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
HELMLDPP_01050	0.0	-	-	-	S	-	-	-	COG NOG06390 non supervised orthologous group
HELMLDPP_01051	5.77e-68	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01052	7.02e-59	-	-	-	D	-	-	-	Septum formation initiator
HELMLDPP_01053	0.0	dnaX	2.7.7.7	-	H	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HELMLDPP_01054	9.88e-205	-	-	-	E	ko:K08717	-	ko00000,ko02000	urea transporter
HELMLDPP_01056	1.85e-113	queF	1.7.1.13	-	H	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HELMLDPP_01057	7.48e-162	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HELMLDPP_01058	1.61e-154	yhhQ	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HELMLDPP_01059	9.93e-307	rocD	2.6.1.13	-	H	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Aminotransferase class-III
HELMLDPP_01060	2.86e-215	-	-	-	S	-	-	-	Amidinotransferase
HELMLDPP_01061	2.92e-230	-	-	-	E	-	-	-	Amidinotransferase
HELMLDPP_01062	1.99e-154	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HELMLDPP_01063	3.39e-180	lipB	3.1.4.55	-	S	ko:K06167	ko00440,map00440	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01064	3.76e-244	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HELMLDPP_01065	3.21e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01066	5.56e-245	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HELMLDPP_01067	6.74e-287	-	-	-	EGP	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01068	1.89e-277	-	-	-	S	-	-	-	COG NOG25407 non supervised orthologous group
HELMLDPP_01069	2.45e-145	-	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01070	1.85e-239	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	COG COG0147 Anthranilate para-aminobenzoate synthases component I
HELMLDPP_01072	0.0	-	-	-	O	-	-	-	COG NOG25094 non supervised orthologous group
HELMLDPP_01073	5.43e-260	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	hydrolase, family 43
HELMLDPP_01074	1.04e-247	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_01075	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HELMLDPP_01076	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01077	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01078	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01079	1.92e-289	mro_1	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HELMLDPP_01080	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_01081	5.13e-288	-	-	-	CO	-	-	-	Domain of unknown function (DUF4369)
HELMLDPP_01082	0.0	-	-	-	CO	-	-	-	Thioredoxin
HELMLDPP_01083	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01084	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01085	1.56e-254	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_01086	6.49e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_01088	3.46e-266	-	-	-	M	ko:K07282	-	ko00000	Bacterial capsule synthesis protein
HELMLDPP_01089	5.52e-208	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HELMLDPP_01090	1.6e-304	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HELMLDPP_01091	1.4e-298	-	-	-	V	-	-	-	MATE efflux family protein
HELMLDPP_01092	0.0	-	-	-	I	ko:K06076	-	ko00000,ko02000	COG COG2067 Long-chain fatty acid transport protein
HELMLDPP_01093	3.5e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_01094	1.12e-265	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01095	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HELMLDPP_01096	1.11e-304	-	-	-	-	-	-	-	-
HELMLDPP_01097	8.7e-297	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Psort location Cytoplasmic, score
HELMLDPP_01098	2.37e-221	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_01099	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01100	0.0	-	-	-	S	-	-	-	COG NOG26858 non supervised orthologous group
HELMLDPP_01101	1.09e-253	-	-	-	U	-	-	-	Sodium:dicarboxylate symporter family
HELMLDPP_01102	4.55e-242	-	-	-	CO	-	-	-	Redoxin
HELMLDPP_01103	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4091)
HELMLDPP_01104	2.25e-240	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HELMLDPP_01105	0.0	-	-	-	S	-	-	-	COG NOG34047 non supervised orthologous group
HELMLDPP_01106	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HELMLDPP_01107	1.01e-145	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_01108	0.0	-	-	-	-	-	-	-	-
HELMLDPP_01109	0.0	-	-	-	-	-	-	-	-
HELMLDPP_01110	1.33e-228	-	-	-	-	-	-	-	-
HELMLDPP_01111	1.43e-225	-	-	-	-	-	-	-	-
HELMLDPP_01112	2.31e-69	-	-	-	S	-	-	-	Conserved protein
HELMLDPP_01113	1.77e-130	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_01114	6.15e-146	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01115	0.0	cobN	6.6.1.2	-	H	ko:K02230	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1429 Cobalamin biosynthesis protein CobN and related
HELMLDPP_01116	0.0	hmuR	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_01117	2.82e-160	-	-	-	S	-	-	-	HmuY protein
HELMLDPP_01118	1.19e-102	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
HELMLDPP_01119	1.63e-67	-	-	-	-	-	-	-	-
HELMLDPP_01120	1.47e-210	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01121	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
HELMLDPP_01122	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_01123	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01124	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01125	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_01126	7.37e-222	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_01127	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HELMLDPP_01128	9.69e-295	-	-	-	M	ko:K03286	-	ko00000,ko02000	Belongs to the ompA family
HELMLDPP_01130	0.0	-	-	-	K	-	-	-	Tetratricopeptide repeat
HELMLDPP_01131	0.0	dsbD	1.8.1.8	-	CO	ko:K04084	-	ko00000,ko01000,ko03110	cytochrome c biogenesis protein transmembrane region
HELMLDPP_01132	1.25e-301	-	-	-	S	-	-	-	Belongs to the UPF0597 family
HELMLDPP_01133	1.35e-60	-	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HELMLDPP_01134	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01135	3.43e-154	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01136	0.0	agcS	-	-	E	ko:K03310	-	ko00000	amino acid carrier protein
HELMLDPP_01137	1.3e-150	-	-	-	S	-	-	-	COG NOG25304 non supervised orthologous group
HELMLDPP_01138	1.79e-138	mug	-	-	L	-	-	-	COG3663 G T U mismatch-specific DNA glycosylase
HELMLDPP_01140	1.69e-135	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HELMLDPP_01141	1.68e-76	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	Psort location Cytoplasmic, score
HELMLDPP_01142	1.28e-73	-	-	-	S	ko:K09790	-	ko00000	Psort location CytoplasmicMembrane, score
HELMLDPP_01143	4.56e-45	-	-	-	S	-	-	-	COG NOG23407 non supervised orthologous group
HELMLDPP_01144	3.49e-63	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HELMLDPP_01145	0.0	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HELMLDPP_01146	3.69e-188	-	-	-	-	-	-	-	-
HELMLDPP_01147	2.74e-208	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01148	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HELMLDPP_01149	1.85e-307	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HELMLDPP_01150	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	single-stranded-DNA-specific exonuclease recJ
HELMLDPP_01151	0.0	recQ2	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HELMLDPP_01152	0.0	-	3.2.1.35	-	G	ko:K01197	ko00531,ko01100,map00531,map01100	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	beta-N-acetylglucosaminidase
HELMLDPP_01153	7.3e-100	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01154	6.55e-227	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01155	8.65e-300	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HELMLDPP_01156	1.06e-122	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1 PfpI family protein
HELMLDPP_01157	5.87e-83	-	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HELMLDPP_01158	7.54e-204	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01159	6.08e-297	dapL	2.6.1.83	-	E	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
HELMLDPP_01160	2e-264	pheB	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01161	3.41e-184	tyrA	1.3.1.12	-	E	ko:K00210	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HELMLDPP_01162	0.000126	-	-	-	-	-	-	-	-
HELMLDPP_01163	8.74e-62	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HELMLDPP_01164	1.05e-227	-	-	-	O	ko:K06889	-	ko00000	COG COG1073 Hydrolases of the alpha beta superfamily
HELMLDPP_01165	0.0	-	-	-	H	-	-	-	COG4206 Outer membrane cobalamin receptor protein
HELMLDPP_01166	6.26e-251	-	-	-	S	-	-	-	amine dehydrogenase activity
HELMLDPP_01167	0.0	-	-	-	K	-	-	-	Putative DNA-binding domain
HELMLDPP_01168	7.1e-275	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HELMLDPP_01169	1.26e-225	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HELMLDPP_01170	5.96e-240	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HELMLDPP_01171	5.57e-306	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HELMLDPP_01172	1.63e-301	-	5.4.2.12	-	G	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	homoserine kinase
HELMLDPP_01173	0.0	thrA	1.1.1.3, 2.7.2.4	-	E	ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HELMLDPP_01174	5.36e-215	-	-	-	M	-	-	-	COG NOG19097 non supervised orthologous group
HELMLDPP_01175	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HELMLDPP_01176	9.15e-158	-	-	-	S	-	-	-	Protein of unknown function (DUF1847)
HELMLDPP_01177	0.0	-	-	-	S	ko:K07137	-	ko00000	FAD-dependent
HELMLDPP_01178	2.72e-124	isiB	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
HELMLDPP_01179	0.0	bfmBAB	1.2.4.4	-	C	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	dehydrogenase E1 component
HELMLDPP_01180	1.15e-313	bfmBB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
HELMLDPP_01181	1.83e-180	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HELMLDPP_01182	0.0	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dihydrolipoyl dehydrogenase
HELMLDPP_01183	2.83e-144	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HELMLDPP_01184	0.0	-	-	-	M	ko:K02014	-	ko00000,ko02000	Psort location OuterMembrane, score 10.00
HELMLDPP_01185	3.3e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01186	0.0	prtQ	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HELMLDPP_01187	2.22e-229	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HELMLDPP_01188	0.0	-	-	-	S	-	-	-	Oxidoreductase NAD-binding domain protein
HELMLDPP_01189	1.79e-266	-	-	-	MU	-	-	-	outer membrane efflux protein
HELMLDPP_01190	0.0	czcA	-	-	P	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_01191	7.38e-261	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_01192	1.73e-123	-	-	-	-	-	-	-	-
HELMLDPP_01193	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HELMLDPP_01194	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HELMLDPP_01195	0.0	-	-	-	S	ko:K09955	-	ko00000	Domain of unknown function
HELMLDPP_01196	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01197	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01198	6.73e-243	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_01199	7.57e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_01200	0.0	rhgT_2	3.1.1.11	-	EG	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Extracellular, score
HELMLDPP_01201	2.46e-215	-	-	-	E	-	-	-	COG NOG17363 non supervised orthologous group
HELMLDPP_01202	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_01203	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HELMLDPP_01204	3.37e-180	-	-	-	L	-	-	-	COG NOG19076 non supervised orthologous group
HELMLDPP_01205	3.02e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HELMLDPP_01206	5.82e-116	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HELMLDPP_01207	2.14e-156	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01208	0.0	-	3.4.14.4	-	S	ko:K01277	-	ko00000,ko01000,ko01002	Peptidase family M49
HELMLDPP_01209	6.89e-102	-	-	-	K	-	-	-	transcriptional regulator (AraC
HELMLDPP_01210	0.0	recQ3	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HELMLDPP_01211	2.67e-137	-	-	-	S	-	-	-	COG COG0457 FOG TPR repeat
HELMLDPP_01212	2.2e-119	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HELMLDPP_01213	1.99e-284	resA	-	-	O	-	-	-	Thioredoxin
HELMLDPP_01214	2.6e-259	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HELMLDPP_01215	0.0	leuA_1	2.3.1.182	-	E	ko:K09011	ko00290,ko00660,ko01100,ko01210,ko01230,map00290,map00660,map01100,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the alpha-IPM synthase homocitrate synthase family
HELMLDPP_01216	1.26e-143	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HELMLDPP_01217	0.0	leuC	4.2.1.33, 4.2.1.35	-	H	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HELMLDPP_01218	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HELMLDPP_01219	3.11e-219	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01220	2.2e-253	-	-	-	S	-	-	-	COG NOG25022 non supervised orthologous group
HELMLDPP_01221	1.46e-172	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HELMLDPP_01222	1.51e-146	dinD	-	-	S	ko:K14623	-	ko00000,ko03400	DNA-damage-inducible protein D
HELMLDPP_01223	4.11e-284	spmA	-	-	S	ko:K06373	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01224	3.55e-313	arlS_2	-	-	T	-	-	-	histidine kinase DNA gyrase B
HELMLDPP_01225	1.1e-159	cusR	-	-	T	ko:K07665	ko02020,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	Transcriptional regulatory protein, C terminal
HELMLDPP_01226	0.0	czcA_1	-	-	P	ko:K15726	-	ko00000,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_01227	5.23e-256	czcB	-	-	M	ko:K15727	-	ko00000,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_01228	2e-284	czcC	-	-	MU	ko:K15725	-	ko00000,ko02000	Outer membrane efflux protein
HELMLDPP_01229	1.24e-98	ybeY	-	-	S	-	-	-	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HELMLDPP_01230	2.06e-125	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_01231	1.94e-245	yqiK	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	SPFH Band 7 PHB domain protein
HELMLDPP_01232	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HELMLDPP_01233	1.19e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HELMLDPP_01234	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HELMLDPP_01235	2.44e-104	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HELMLDPP_01236	1.85e-69	ypjD	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HELMLDPP_01237	1.66e-220	deoC	4.1.2.4	-	H	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HELMLDPP_01238	4.96e-222	ispB	2.5.1.90	-	H	ko:K02523	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HELMLDPP_01239	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HELMLDPP_01241	1.14e-87	-	-	-	S	-	-	-	COG NOG29882 non supervised orthologous group
HELMLDPP_01242	5.47e-259	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HELMLDPP_01243	8.92e-219	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HELMLDPP_01244	2.17e-204	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HELMLDPP_01245	9.86e-160	-	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	COG4845 Chloramphenicol O-acetyltransferase
HELMLDPP_01246	1.98e-166	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_01247	3.69e-34	-	-	-	-	-	-	-	-
HELMLDPP_01248	9.83e-246	-	-	-	NU	-	-	-	Type IV pilus biogenesis stability protein PilW
HELMLDPP_01249	0.0	-	-	-	NU	-	-	-	Type IV pilus biogenesis stability protein PilW
HELMLDPP_01250	4.96e-144	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_01252	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HELMLDPP_01253	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HELMLDPP_01254	5.77e-123	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HELMLDPP_01255	0.0	-	-	-	-	-	-	-	-
HELMLDPP_01256	1.52e-303	-	-	-	-	-	-	-	-
HELMLDPP_01257	4.59e-237	-	-	-	S	-	-	-	COG NOG32009 non supervised orthologous group
HELMLDPP_01258	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HELMLDPP_01259	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HELMLDPP_01260	1.08e-147	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_01263	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
HELMLDPP_01264	9.67e-317	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HELMLDPP_01265	2.08e-152	-	-	-	L	ko:K03424	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01266	5.8e-51	yidD	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HELMLDPP_01267	7.1e-83	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HELMLDPP_01268	6.62e-178	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HELMLDPP_01269	6.65e-193	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01270	9.96e-135	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HELMLDPP_01271	1.26e-305	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HELMLDPP_01272	0.0	-	-	-	EGP	ko:K08169	-	ko00000,ko02000	the major facilitator superfamily
HELMLDPP_01273	7.6e-151	-	-	-	S	-	-	-	phosphatase family
HELMLDPP_01274	2.84e-288	-	-	-	S	-	-	-	Acyltransferase family
HELMLDPP_01275	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HELMLDPP_01276	3.77e-81	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
HELMLDPP_01277	7.62e-132	-	-	-	-	-	-	-	-
HELMLDPP_01278	2.6e-198	-	-	-	S	-	-	-	Thiol-activated cytolysin
HELMLDPP_01279	6.35e-62	-	-	-	S	-	-	-	Thiol-activated cytolysin
HELMLDPP_01282	1.42e-102	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase
HELMLDPP_01283	1.5e-257	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HELMLDPP_01284	1.83e-168	truB	5.4.99.25	-	J	ko:K03177	-	ko00000,ko01000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HELMLDPP_01285	9.72e-184	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HELMLDPP_01286	7.5e-53	fjo13	-	-	S	-	-	-	COG NOG19122 non supervised orthologous group
HELMLDPP_01287	6.79e-191	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Belongs to the ABC-4 integral membrane protein family. FtsX subfamily
HELMLDPP_01288	1.64e-218	-	-	-	H	-	-	-	Methyltransferase domain protein
HELMLDPP_01289	1.67e-50	-	-	-	KT	-	-	-	PspC domain protein
HELMLDPP_01290	2.76e-95	mip	5.2.1.8	-	O	ko:K01802	-	ko00000,ko01000	COG COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1
HELMLDPP_01291	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HELMLDPP_01292	3.56e-65	-	-	-	-	-	-	-	-
HELMLDPP_01293	0.0	scpC	2.8.3.18, 3.1.2.1	-	C	ko:K01067,ko:K18118	ko00020,ko00620,ko00650,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00650,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0427 Acetyl-CoA hydrolase
HELMLDPP_01294	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain protein
HELMLDPP_01295	0.0	-	-	-	S	-	-	-	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HELMLDPP_01296	0.0	-	3.1.6.1	-	P	ko:K01130	ko00140,ko00600,map00140,map00600	ko00000,ko00001,ko01000	Arylsulfatase
HELMLDPP_01297	0.0	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HELMLDPP_01298	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01299	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01300	6.18e-238	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_01301	1.26e-137	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_01302	0.0	-	-	-	M	ko:K08676	-	ko00000,ko01000,ko01002	Tricorn protease homolog
HELMLDPP_01303	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01304	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01305	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_01306	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HELMLDPP_01307	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HELMLDPP_01308	2.43e-209	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01309	1.24e-125	-	-	-	J	-	-	-	COG COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HELMLDPP_01310	4.75e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HELMLDPP_01312	4.33e-235	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HELMLDPP_01313	9.06e-125	spoU	-	-	J	-	-	-	RNA methylase, SpoU family K00599
HELMLDPP_01314	3.86e-112	-	-	-	S	-	-	-	COG NOG14459 non supervised orthologous group
HELMLDPP_01315	0.0	-	-	-	L	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01316	6.17e-192	-	-	-	C	-	-	-	radical SAM domain protein
HELMLDPP_01317	8.05e-166	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_01318	9.28e-307	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01322	1.71e-14	-	-	-	-	-	-	-	-
HELMLDPP_01324	1.71e-49	-	-	-	-	-	-	-	-
HELMLDPP_01325	4.51e-24	-	-	-	-	-	-	-	-
HELMLDPP_01326	1.41e-36	-	-	-	-	-	-	-	-
HELMLDPP_01329	2.25e-83	-	-	-	-	-	-	-	-
HELMLDPP_01330	7.56e-208	-	-	-	S	-	-	-	COG NOG37815 non supervised orthologous group
HELMLDPP_01331	6.63e-26	-	-	-	-	-	-	-	-
HELMLDPP_01332	1.88e-43	-	-	-	-	-	-	-	-
HELMLDPP_01336	4.31e-278	-	-	-	M	ko:K20345	ko02024,map02024	ko00000,ko00001,ko02000	HlyD family secretion protein
HELMLDPP_01337	0.0	lagD	-	-	V	ko:K20344	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko02000	Papain-like cysteine protease AvrRpt2
HELMLDPP_01338	5.38e-291	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Outer membrane efflux protein
HELMLDPP_01339	0.0	sulP	-	-	P	ko:K03321	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01340	5.19e-59	-	-	-	S	-	-	-	Domain of unknown function (DUF4884)
HELMLDPP_01341	2.87e-137	rbr	-	-	C	-	-	-	Rubrerythrin
HELMLDPP_01342	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01343	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
HELMLDPP_01344	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01345	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01346	6.79e-59	-	-	-	S	-	-	-	Cysteine-rich CWC
HELMLDPP_01347	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Anaerobic ribonucleoside-triphosphate reductase
HELMLDPP_01348	3.04e-114	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	anaerobic ribonucleoside-triphosphate reductase activating protein
HELMLDPP_01349	1.56e-301	-	4.99.1.3	-	H	ko:K02190	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Cobalt chelatase (CbiK)
HELMLDPP_01350	0.0	-	-	-	M	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_01351	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_01352	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01353	0.0	cbiA	6.3.5.11, 6.3.5.9	-	H	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HELMLDPP_01354	6.54e-138	-	-	-	S	-	-	-	ATP cob(I)alamin adenosyltransferase
HELMLDPP_01355	0.0	cobQ	6.3.5.10	-	H	ko:K02232	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HELMLDPP_01356	3.78e-248	-	4.1.1.81	-	E	ko:K04720	ko00860,map00860	ko00000,ko00001,ko01000	COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase
HELMLDPP_01357	7.62e-219	cobD	6.3.1.10	-	H	ko:K02227	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HELMLDPP_01359	2.01e-65	-	-	-	S	-	-	-	Protein of unknown function (DUF1622)
HELMLDPP_01360	3.43e-128	cobC	3.1.3.73	-	G	ko:K02226	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01361	1.69e-180	cobS	2.7.8.26	-	H	ko:K02233	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HELMLDPP_01362	5.22e-255	cobT	2.4.2.21	-	F	ko:K00768	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HELMLDPP_01363	1.93e-117	cobU	2.7.1.156, 2.7.7.62	-	H	ko:K02231	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	bifunctional cobalamin biosynthesis protein
HELMLDPP_01364	4.34e-121	-	-	-	T	-	-	-	FHA domain protein
HELMLDPP_01365	4.68e-260	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
HELMLDPP_01366	0.0	ugd	1.1.1.22	-	C	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HELMLDPP_01367	2.94e-192	-	-	-	S	-	-	-	COG NOG26711 non supervised orthologous group
HELMLDPP_01368	1.24e-297	deaD	-	-	L	-	-	-	Belongs to the DEAD box helicase family
HELMLDPP_01369	1.48e-287	serB	3.1.3.3	-	ET	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01009	Psort location Cytoplasmic, score 8.96
HELMLDPP_01370	2.36e-111	-	-	-	O	-	-	-	COG NOG28456 non supervised orthologous group
HELMLDPP_01371	1.93e-151	-	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	HAD hydrolase, family IA, variant 3
HELMLDPP_01372	7.16e-278	lptG	-	-	S	ko:K11720	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
HELMLDPP_01373	8.11e-286	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HELMLDPP_01374	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HELMLDPP_01375	2.81e-167	smtA	2.1.1.223	-	J	ko:K15460	-	ko00000,ko01000,ko03016	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
HELMLDPP_01376	1.22e-248	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
HELMLDPP_01377	1.66e-290	bioF	2.3.1.29, 2.3.1.47	-	E	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Beta-eliminating lyase
HELMLDPP_01378	6.08e-197	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01379	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HELMLDPP_01380	1.75e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
HELMLDPP_01381	0.0	-	-	-	V	-	-	-	MacB-like periplasmic core domain
HELMLDPP_01382	0.0	-	-	-	V	-	-	-	Efflux ABC transporter, permease protein
HELMLDPP_01383	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01384	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01385	3e-274	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HELMLDPP_01386	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01387	1.03e-65	-	-	-	KLT	ko:K07126	-	ko00000	COG0790 FOG TPR repeat, SEL1 subfamily
HELMLDPP_01388	0.0	-	-	-	T	-	-	-	Sigma-54 interaction domain protein
HELMLDPP_01389	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01391	1.41e-33	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01392	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01393	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01394	7.39e-106	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01395	2.72e-199	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_01396	3.95e-273	bcr	-	-	EGP	ko:K03446,ko:K07552	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_01397	9.52e-204	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_01398	3.19e-132	-	-	-	S	-	-	-	COG NOG27363 non supervised orthologous group
HELMLDPP_01400	2.68e-123	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_01401	4.24e-215	-	-	-	H	-	-	-	Glycosyltransferase, family 11
HELMLDPP_01402	9.97e-119	fldA	-	-	C	ko:K03839	-	ko00000	Low-potential electron donor to a number of redox enzymes
HELMLDPP_01403	2.24e-81	-	-	-	S	-	-	-	Protein of unknown function (DUF2023)
HELMLDPP_01405	1.88e-24	-	-	-	-	-	-	-	-
HELMLDPP_01406	2.34e-66	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin
HELMLDPP_01407	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HELMLDPP_01408	5.93e-124	ogt	2.1.1.63	-	H	ko:K00567,ko:K10778	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HELMLDPP_01409	1.2e-131	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
HELMLDPP_01410	6.07e-222	-	3.5.1.53	-	S	ko:K12251	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	hydrolase, carbon-nitrogen family
HELMLDPP_01411	2.4e-258	aguA	3.5.3.12	-	E	ko:K10536	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01412	0.0	-	-	-	S	-	-	-	Psort location OuterMembrane, score 9.49
HELMLDPP_01413	1.13e-127	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01414	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01415	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HELMLDPP_01416	2.82e-192	-	-	-	-	-	-	-	-
HELMLDPP_01417	0.0	rfbH	1.17.1.1	-	E	ko:K12452	ko00520,map00520	ko00000,ko00001,ko01000	DegT/DnrJ/EryC1/StrS aminotransferase family
HELMLDPP_01418	5.27e-189	rfbF	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HELMLDPP_01420	5.02e-255	rfbG	4.2.1.45	-	M	ko:K01709	ko00520,map00520	ko00000,ko00001,ko01000	Polysaccharide biosynthesis protein
HELMLDPP_01422	8.67e-96	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	transketolase activity
HELMLDPP_01423	3.73e-101	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
HELMLDPP_01424	3.17e-07	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_01425	3.49e-119	-	-	-	S	-	-	-	Glycosyltransferase family 10 (fucosyltransferase) C-term
HELMLDPP_01426	3.62e-98	rfbX	-	-	S	-	-	-	polysaccharide biosynthetic process
HELMLDPP_01427	9.17e-47	-	-	-	S	-	-	-	Glycosyltransferase family 17
HELMLDPP_01428	5.27e-119	-	-	-	S	-	-	-	O-antigen ligase like membrane protein
HELMLDPP_01429	3.75e-97	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_01430	3.85e-46	-	2.3.1.30	-	M	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Hexapeptide repeat of succinyl-transferase
HELMLDPP_01431	9.88e-205	-	-	-	GM	-	-	-	3-beta hydroxysteroid dehydrogenase/isomerase family
HELMLDPP_01432	2.84e-16	-	-	-	G	-	-	-	Cupin domain
HELMLDPP_01433	1.38e-140	-	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Glycosyl transferase WecB/TagA/CpsF family
HELMLDPP_01434	2.43e-201	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_01435	1.52e-199	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01436	2.31e-27	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01437	6.42e-218	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01439	0.0	-	-	-	L	-	-	-	helicase
HELMLDPP_01440	0.0	nqrA	1.6.5.8	-	C	ko:K00346	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HELMLDPP_01441	9.62e-289	nqrB	1.6.5.8	-	C	ko:K00347	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HELMLDPP_01442	1.34e-160	nqrC	1.6.5.8	-	C	ko:K00348	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HELMLDPP_01443	6.11e-142	nqrD	1.6.5.8	-	C	ko:K00349	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HELMLDPP_01444	1.33e-120	nqrE	1.6.5.8	-	C	ko:K00350	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HELMLDPP_01445	0.0	nqrF	1.6.5.8	-	C	ko:K00351	-	ko00000,ko01000	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway
HELMLDPP_01446	0.0	dbpA	3.6.4.13	-	L	ko:K05591	-	ko00000,ko01000,ko03009	ATP-independent RNA helicase DbpA
HELMLDPP_01447	9.84e-261	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HELMLDPP_01448	1.21e-213	serA	1.1.1.399, 1.1.1.95	-	C	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HELMLDPP_01449	2.74e-306	-	-	-	S	-	-	-	Conserved protein
HELMLDPP_01450	2.99e-197	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01451	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HELMLDPP_01452	1.46e-50	-	-	-	S	-	-	-	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HELMLDPP_01453	1.24e-121	-	-	-	S	-	-	-	protein containing a ferredoxin domain
HELMLDPP_01454	2.71e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HELMLDPP_01455	1.23e-275	rmuC	-	-	S	ko:K09760	-	ko00000	RmuC family
HELMLDPP_01456	6.59e-151	-	-	-	S	ko:K07507	-	ko00000,ko02000	Mg2 transporter-C family protein
HELMLDPP_01457	0.0	covS	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01458	4.52e-262	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Psort location Cytoplasmic, score 8.96
HELMLDPP_01459	6.19e-195	-	-	-	S	-	-	-	COG4422 Bacteriophage protein gp37
HELMLDPP_01460	9.73e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01461	3.09e-244	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	COG0010 Arginase agmatinase formimionoglutamate hydrolase arginase family
HELMLDPP_01462	2.31e-84	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01463	2.73e-198	-	-	-	Q	-	-	-	COG NOG10855 non supervised orthologous group
HELMLDPP_01464	1.2e-109	yvbK	2.3.1.82	-	K	ko:K03827,ko:K18815	-	br01600,ko00000,ko01000,ko01504	Psort location Cytoplasmic, score 8.96
HELMLDPP_01465	8.86e-226	per1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	COG2367 Beta-lactamase class A
HELMLDPP_01466	2.46e-118	proX	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HELMLDPP_01467	0.0	-	3.2.1.3	GH15	G	ko:K01178	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolases family 15
HELMLDPP_01468	0.0	otsB	2.4.1.15, 3.1.3.12	GT20	G	ko:K16055	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000,ko01003	Trehalose-phosphatase
HELMLDPP_01469	0.0	-	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Aspartate kinase
HELMLDPP_01470	1.99e-151	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HELMLDPP_01471	3.17e-166	-	-	-	S	ko:K07025	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01472	2.82e-171	-	-	-	S	-	-	-	non supervised orthologous group
HELMLDPP_01474	2.02e-131	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HELMLDPP_01475	0.0	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HELMLDPP_01476	0.0	kdpA	3.6.3.12	-	P	ko:K01546	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HELMLDPP_01477	8.49e-118	-	-	-	S	-	-	-	Appr-1'-p processing enzyme
HELMLDPP_01479	4.67e-316	-	-	-	T	ko:K02481	-	ko00000,ko02022	acetoacetate metabolism regulatory protein AtoC
HELMLDPP_01480	1.06e-279	proV	3.6.3.32	-	P	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG4175 ABC-type proline glycine betaine transport system, ATPase component
HELMLDPP_01481	5.86e-189	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine transport system, permease
HELMLDPP_01482	4.54e-205	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
HELMLDPP_01483	2.09e-212	-	-	-	EG	-	-	-	EamA-like transporter family
HELMLDPP_01484	4.29e-130	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Psort location Cytoplasmic, score 9.97
HELMLDPP_01485	6.33e-50	-	-	-	S	-	-	-	COG NOG33517 non supervised orthologous group
HELMLDPP_01486	7.31e-213	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HELMLDPP_01487	4.58e-246	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HELMLDPP_01488	7.87e-111	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HELMLDPP_01489	3.44e-58	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HELMLDPP_01490	1.43e-35	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HELMLDPP_01491	5.89e-28	-	-	-	S	-	-	-	Domain of unknown function (DUF4295)
HELMLDPP_01492	1.31e-219	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HELMLDPP_01493	3.66e-315	rimO	2.8.4.4	-	J	ko:K14441	-	ko00000,ko01000,ko03009	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
HELMLDPP_01494	1.49e-54	himA	-	-	L	ko:K03530,ko:K04764	-	ko00000,ko03032,ko03036,ko03400	COG0776 Bacterial nucleoid DNA-binding protein
HELMLDPP_01495	0.0	-	-	-	L	-	-	-	Belongs to the bacterial histone-like protein family
HELMLDPP_01496	5.5e-218	moxR	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HELMLDPP_01497	1.65e-207	-	-	-	S	-	-	-	protein (some members contain a von Willebrand factor type A (vWA) domain)
HELMLDPP_01498	1.75e-254	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01499	3.82e-230	batA	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HELMLDPP_01500	2.82e-236	batB	-	-	S	ko:K07114	-	ko00000,ko02000	Von Willebrand factor type A domain
HELMLDPP_01501	1.66e-116	batC	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_01502	0.0	batD	-	-	S	-	-	-	COG NOG06393 non supervised orthologous group
HELMLDPP_01503	2.01e-179	batE	-	-	T	-	-	-	COG NOG22299 non supervised orthologous group
HELMLDPP_01504	3.8e-161	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01505	1.44e-56	-	-	-	S	-	-	-	COG NOG19094 non supervised orthologous group
HELMLDPP_01506	1.59e-267	uspA	-	-	T	-	-	-	COG0589 Universal stress protein UspA and related nucleotide-binding
HELMLDPP_01507	4.54e-284	-	-	-	S	-	-	-	tetratricopeptide repeat
HELMLDPP_01508	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HELMLDPP_01510	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HELMLDPP_01511	0.0	htpG	-	-	T	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01512	0.0	-	-	-	M	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HELMLDPP_01515	5.8e-78	-	-	-	-	-	-	-	-
HELMLDPP_01516	3.01e-185	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
HELMLDPP_01517	4.7e-136	exbD1	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
HELMLDPP_01518	4.29e-144	exbD2	-	-	U	-	-	-	Biopolymer transport protein ExbD/TolR
HELMLDPP_01519	8.56e-180	tonB2	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HELMLDPP_01520	2.47e-224	-	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	COG0226 ABC-type phosphate transport system, periplasmic component
HELMLDPP_01521	0.0	-	-	-	S	-	-	-	tetratricopeptide repeat
HELMLDPP_01522	1.99e-199	cbiO	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_01523	5.97e-209	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01524	8.26e-80	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01525	0.0	-	-	-	M	-	-	-	PA domain
HELMLDPP_01526	8.4e-295	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01527	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01528	8.08e-242	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HELMLDPP_01529	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HELMLDPP_01530	2.77e-119	-	-	-	S	-	-	-	COG NOG27649 non supervised orthologous group
HELMLDPP_01531	1.27e-135	-	-	-	S	-	-	-	Zeta toxin
HELMLDPP_01532	2.43e-49	-	-	-	-	-	-	-	-
HELMLDPP_01533	4.02e-109	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HELMLDPP_01534	7.16e-82	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HELMLDPP_01535	4.28e-189	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HELMLDPP_01536	3.1e-223	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HELMLDPP_01537	1.51e-71	-	-	-	J	ko:K03113	ko03013,map03013	ko00000,ko00001,ko03012	COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related
HELMLDPP_01538	2.51e-152	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HELMLDPP_01539	5.74e-148	fahA	-	-	Q	-	-	-	2-hydroxyhepta-2,4-diene-1,7-dioate isomerase, fumarylacetoacetate hydrolase family K01828
HELMLDPP_01540	3.52e-111	ispF	4.6.1.12	-	H	ko:K01770	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HELMLDPP_01541	7.9e-214	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HELMLDPP_01542	1.41e-203	-	-	-	S	ko:K07098	-	ko00000	Ser Thr phosphatase family protein
HELMLDPP_01543	3.04e-110	-	-	-	S	-	-	-	Family of unknown function (DUF3836)
HELMLDPP_01544	7.66e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HELMLDPP_01545	1.71e-33	-	-	-	-	-	-	-	-
HELMLDPP_01546	7.92e-129	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HELMLDPP_01547	3.04e-203	-	-	-	S	-	-	-	stress-induced protein
HELMLDPP_01548	7.77e-167	yeaZ	-	-	O	ko:K14742	-	ko00000,ko03016	Universal bacterial protein YeaZ
HELMLDPP_01549	9.47e-144	-	-	-	S	-	-	-	COG NOG11645 non supervised orthologous group
HELMLDPP_01550	1.68e-312	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HELMLDPP_01551	9.14e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HELMLDPP_01552	2.51e-200	nlpD_1	-	-	M	-	-	-	Peptidase, M23 family
HELMLDPP_01553	1.08e-268	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HELMLDPP_01554	0.0	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HELMLDPP_01555	1.71e-114	nrdG	1.97.1.4	-	C	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HELMLDPP_01556	0.0	nrdD	1.1.98.6	-	FK	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01557	1.71e-161	hly-III	-	-	S	ko:K11068	-	ko00000,ko02042	membrane protein, hemolysin III homolog
HELMLDPP_01558	0.0	cca	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	tRNA nucleotidyltransferase poly(A) polymerase
HELMLDPP_01559	7.65e-185	-	-	-	-	-	-	-	-
HELMLDPP_01560	1.25e-129	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HELMLDPP_01561	1.93e-211	ddh	1.4.1.16	-	E	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
HELMLDPP_01562	7.88e-209	lgt	-	-	M	-	-	-	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HELMLDPP_01563	1.46e-140	-	-	-	L	-	-	-	DNA-binding protein
HELMLDPP_01564	0.0	scrL	-	-	P	-	-	-	TonB-dependent receptor
HELMLDPP_01565	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HELMLDPP_01566	4.05e-266	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HELMLDPP_01567	1.27e-216	ydjH_1	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family
HELMLDPP_01568	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_01569	2.12e-92	-	-	-	S	-	-	-	ACT domain protein
HELMLDPP_01570	1.23e-313	paaK	6.2.1.30	-	H	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	ko00000,ko00001,ko01000	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HELMLDPP_01571	1.51e-147	-	-	-	S	-	-	-	COG NOG19149 non supervised orthologous group
HELMLDPP_01572	5.8e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HELMLDPP_01573	1.84e-261	fba	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01574	1.76e-196	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
HELMLDPP_01575	5.12e-255	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_01576	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_01577	5.46e-316	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HELMLDPP_01578	3.9e-308	-	-	-	S	-	-	-	protein BT3056 SWALL AAO78162 (EMBL AE016938) (409 aa) fasta scores E()
HELMLDPP_01579	7.67e-124	-	-	-	S	-	-	-	COG NOG23374 non supervised orthologous group
HELMLDPP_01580	0.0	-	-	-	G	-	-	-	Transporter, major facilitator family protein
HELMLDPP_01581	3.79e-250	-	-	-	S	-	-	-	Domain of unknown function (DUF4831)
HELMLDPP_01582	0.0	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HELMLDPP_01583	1.76e-122	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HELMLDPP_01584	3.36e-130	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HELMLDPP_01585	3.21e-267	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HELMLDPP_01586	1.84e-194	-	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HELMLDPP_01587	9.82e-156	-	-	-	S	-	-	-	B3 4 domain protein
HELMLDPP_01588	1.41e-149	nlpD_2	-	-	M	-	-	-	COG COG0739 Membrane proteins related to metalloendopeptidases
HELMLDPP_01589	1.85e-36	-	-	-	-	-	-	-	-
HELMLDPP_01590	6.37e-125	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_01591	2.69e-73	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_01592	1.38e-43	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_01593	4.93e-158	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
HELMLDPP_01594	5.16e-292	purH2	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful)
HELMLDPP_01595	2.49e-84	-	-	-	S	-	-	-	Protein of unknown function, DUF488
HELMLDPP_01596	1.38e-113	yncA	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	(GNAT) family
HELMLDPP_01597	3.52e-96	-	-	-	K	-	-	-	FR47-like protein
HELMLDPP_01598	1.03e-132	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01599	0.0	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01600	1.82e-28	-	-	-	-	-	-	-	-
HELMLDPP_01601	3.27e-19	-	-	-	M	-	-	-	COG NOG19089 non supervised orthologous group
HELMLDPP_01602	1.01e-276	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01604	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01606	1.44e-155	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HELMLDPP_01607	2.39e-121	-	-	-	S	ko:K07089	-	ko00000	Predicted permease
HELMLDPP_01608	1.56e-46	-	-	-	CO	-	-	-	redox-active disulfide protein 2
HELMLDPP_01609	1.34e-66	dsbD	1.8.1.8	-	CO	ko:K04084,ko:K06196	-	ko00000,ko01000,ko02000,ko03110	protein-disulfide reductase activity
HELMLDPP_01610	1.49e-24	-	-	-	CO	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01611	6.9e-43	-	-	-	-	-	-	-	-
HELMLDPP_01613	1.98e-74	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01615	1.2e-58	-	-	-	J	-	-	-	gnat family
HELMLDPP_01616	0.0	-	-	-	L	-	-	-	Integrase core domain
HELMLDPP_01617	3.42e-19	-	-	-	L	-	-	-	IstB-like ATP binding protein
HELMLDPP_01619	1.27e-247	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HELMLDPP_01620	1.07e-93	hinT	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family
HELMLDPP_01621	3.41e-97	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HELMLDPP_01622	1.18e-272	-	-	-	O	-	-	-	COG NOG14454 non supervised orthologous group
HELMLDPP_01623	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HELMLDPP_01624	8.53e-38	rubR	-	-	C	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_01625	1.69e-167	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HELMLDPP_01626	2.26e-135	fklB	5.2.1.8	-	G	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Peptidyl-prolyl cis-trans isomerase
HELMLDPP_01627	3.54e-197	-	5.2.1.8	-	M	ko:K03772,ko:K03773	-	ko00000,ko01000,ko03110	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase
HELMLDPP_01628	3.46e-113	-	-	-	L	-	-	-	Transposase, Mutator family
HELMLDPP_01629	4.26e-111	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
HELMLDPP_01630	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01631	0.0	-	-	-	P	ko:K03324	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01632	0.0	udk2	2.7.1.48	-	FJ	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Phosphoribulokinase Uridine kinase family
HELMLDPP_01633	0.0	-	2.3.1.54, 4.1.1.83	-	C	ko:K00656,ko:K18427	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HELMLDPP_01634	1.31e-215	-	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	4Fe-4S single cluster domain
HELMLDPP_01635	0.0	pepP	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HELMLDPP_01636	3.83e-314	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog
HELMLDPP_01637	6.34e-147	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01638	4.01e-87	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HELMLDPP_01639	2.14e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HELMLDPP_01640	0.0	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HELMLDPP_01641	9.64e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HELMLDPP_01642	1.04e-69	-	-	-	S	-	-	-	RNA recognition motif
HELMLDPP_01643	0.0	-	-	-	N	-	-	-	IgA Peptidase M64
HELMLDPP_01644	5.09e-264	envC	-	-	D	-	-	-	Peptidase, M23
HELMLDPP_01645	7.19e-196	-	-	-	S	-	-	-	COG NOG29315 non supervised orthologous group
HELMLDPP_01646	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_01647	2.38e-99	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HELMLDPP_01648	0.0	dgt	3.1.5.1	-	F	ko:K01129	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01649	4.2e-240	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01650	6.48e-209	-	-	-	I	-	-	-	Acyl-transferase
HELMLDPP_01651	4.33e-109	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HELMLDPP_01652	4.92e-212	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HELMLDPP_01653	8.16e-77	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01654	0.0	ftsI	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	Cell division protein FtsI penicillin-binding protein
HELMLDPP_01655	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HELMLDPP_01656	1.34e-296	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HELMLDPP_01657	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HELMLDPP_01658	1.79e-316	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HELMLDPP_01659	2.53e-264	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HELMLDPP_01660	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HELMLDPP_01661	6.35e-174	ftsQ	-	-	M	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Psort location Cytoplasmic, score 8.96
HELMLDPP_01662	0.0	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HELMLDPP_01663	2.25e-301	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HELMLDPP_01664	3.44e-90	-	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HELMLDPP_01666	4.86e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HELMLDPP_01668	7.11e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HELMLDPP_01669	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HELMLDPP_01671	0.0	malQ	2.4.1.25	GH77	G	ko:K00705	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.26
HELMLDPP_01672	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01673	3.65e-109	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_01674	0.0	-	-	-	D	-	-	-	Domain of unknown function
HELMLDPP_01677	0.0	-	-	-	S	ko:K21557	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01678	0.0	-	3.2.1.135	GH13	G	ko:K21575	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 13 family
HELMLDPP_01679	0.0	susB	3.2.1.20, 3.2.1.3	GH31,GH97	G	ko:K01187,ko:K21574	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HELMLDPP_01680	0.0	-	-	-	P	ko:K21573	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01681	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01682	7.51e-262	-	-	-	S	ko:K21571	-	ko00000	SusE outer membrane protein
HELMLDPP_01684	0.0	susC	-	-	P	ko:K21573	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01685	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01686	1.79e-289	-	-	-	S	ko:K21571	-	ko00000	Outer membrane protein SusF_SusE
HELMLDPP_01687	0.0	-	-	-	S	ko:K21571	-	ko00000	Domain of unknown function (DUF5115)
HELMLDPP_01688	0.0	-	3.2.1.1, 3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	M	ko:K01176,ko:K01208	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Alpha-amylase domain
HELMLDPP_01689	2e-288	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan endo-1,4-beta-galactosidase
HELMLDPP_01690	2.17e-242	-	-	-	M	-	-	-	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HELMLDPP_01691	0.0	-	-	-	O	-	-	-	Psort location Extracellular, score
HELMLDPP_01692	1.42e-291	-	-	-	M	-	-	-	Phosphate-selective porin O and P
HELMLDPP_01693	1.95e-140	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01694	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HELMLDPP_01695	1.35e-236	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01696	0.0	fucI	5.3.1.25, 5.3.1.3	-	G	ko:K01818	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Converts the aldose L-fucose into the corresponding ketose L-fuculose
HELMLDPP_01697	0.0	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
HELMLDPP_01698	2.44e-147	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HELMLDPP_01699	0.0	-	-	-	KT	-	-	-	tetratricopeptide repeat
HELMLDPP_01700	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01701	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01702	6.68e-57	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
HELMLDPP_01703	1.3e-137	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01704	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HELMLDPP_01705	0.0	ygjK	-	GH63	G	ko:K03931	-	ko00000	Glycoside hydrolase
HELMLDPP_01706	7.39e-294	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family
HELMLDPP_01707	0.0	sufD	-	-	O	ko:K09015	-	ko00000	COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component
HELMLDPP_01708	1.62e-174	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component
HELMLDPP_01709	0.0	sufB	-	-	O	ko:K09014	-	ko00000	Cysteine desulfurase
HELMLDPP_01710	2.62e-105	cvpA	-	-	S	ko:K03558	-	ko00000	Psort location CytoplasmicMembrane, score
HELMLDPP_01711	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HELMLDPP_01712	4.46e-293	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HELMLDPP_01713	4.32e-105	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HELMLDPP_01714	5.68e-91	-	-	-	S	-	-	-	COG NOG29451 non supervised orthologous group
HELMLDPP_01715	1.7e-282	araJ	-	-	EGP	ko:K08156	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01716	3.87e-33	-	-	-	-	-	-	-	-
HELMLDPP_01717	3.75e-268	-	-	-	S	-	-	-	Radical SAM superfamily
HELMLDPP_01718	1.23e-228	-	-	-	-	-	-	-	-
HELMLDPP_01720	0.0	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HELMLDPP_01721	6.62e-141	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_01723	7.9e-51	-	-	-	S	-	-	-	transposase or invertase
HELMLDPP_01724	2.28e-139	-	-	-	-	-	-	-	-
HELMLDPP_01725	0.0	-	-	-	Q	-	-	-	COG3458 Acetyl esterase (deacetylase)
HELMLDPP_01726	2.5e-170	-	-	-	S	ko:K07043	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01727	4.34e-139	-	-	-	S	-	-	-	Putative auto-transporter adhesin, head GIN domain
HELMLDPP_01728	6.11e-106	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01729	1.03e-112	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_01730	6.8e-175	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HELMLDPP_01731	0.0	speA	4.1.1.19	-	H	ko:K01585	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the biosynthesis of agmatine from arginine
HELMLDPP_01732	2.82e-122	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HELMLDPP_01733	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HELMLDPP_01734	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01735	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_01736	1.2e-127	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HELMLDPP_01737	1.71e-302	corC_1	-	-	P	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
HELMLDPP_01738	4.86e-84	-	-	-	-	-	-	-	-
HELMLDPP_01739	1.4e-104	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator, AsnC family
HELMLDPP_01740	1.66e-71	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01741	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_01742	1e-92	-	-	-	-	-	-	-	-
HELMLDPP_01743	2.46e-25	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
HELMLDPP_01744	5.74e-304	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HELMLDPP_01745	1.7e-260	buk	2.7.2.7	-	H	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HELMLDPP_01746	1.67e-218	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Phosphate acetyl/butaryl transferase
HELMLDPP_01747	0.0	-	3.4.13.19	-	E	ko:K01273,ko:K01274	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
HELMLDPP_01748	3.01e-253	ywaD	-	-	S	-	-	-	glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683
HELMLDPP_01749	9e-94	sufE	-	-	S	ko:K02426	-	ko00000	COG2166 SufE protein probably involved in Fe-S center assembly
HELMLDPP_01750	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01751	0.0	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
HELMLDPP_01752	7.71e-157	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_01753	1.97e-277	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01754	4e-156	ddpX	3.4.13.22	-	M	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HELMLDPP_01755	5.95e-77	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HELMLDPP_01756	2.3e-111	-	-	-	O	-	-	-	Psort location Cytoplasmic, score 9.26
HELMLDPP_01757	8.69e-48	-	-	-	P	-	-	-	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HELMLDPP_01758	6.03e-152	-	-	-	-	-	-	-	-
HELMLDPP_01759	6.51e-114	-	-	-	-	-	-	-	-
HELMLDPP_01760	0.0	-	-	-	M	-	-	-	Glycosyl Hydrolase Family 88
HELMLDPP_01761	1.86e-268	higA	-	-	K	ko:K18831	-	ko00000,ko02048,ko03000	Pfam:DUF955
HELMLDPP_01762	3.57e-72	-	-	-	S	ko:K07334	-	ko00000,ko02048	RelE-like toxin of type II toxin-antitoxin system HigB
HELMLDPP_01763	2.47e-273	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01764	4.67e-103	-	-	-	-	-	-	-	-
HELMLDPP_01766	0.0	yoaB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01767	2.53e-146	yihX	3.1.3.10, 3.1.3.104	-	S	ko:K07025,ko:K20866,ko:K21063	ko00010,ko00740,ko01100,ko01110,ko01120,map00010,map00740,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01768	1.13e-218	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin biosynthesis protein
HELMLDPP_01770	1.19e-90	-	-	-	S	-	-	-	Family of unknown function (DUF3836)
HELMLDPP_01772	0.0	-	-	-	E	-	-	-	Acetyl xylan esterase (AXE1)
HELMLDPP_01773	3.66e-188	-	-	-	S	ko:K07052	-	ko00000	CAAX amino terminal protease family
HELMLDPP_01774	8.24e-137	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01775	2.06e-144	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01776	8.86e-56	-	-	-	-	-	-	-	-
HELMLDPP_01777	2.41e-35	-	-	-	K	ko:K07727	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HELMLDPP_01778	9.65e-79	-	-	-	P	ko:K08364	-	ko00000,ko02000	Heavy-metal-associated domain
HELMLDPP_01779	0.0	-	-	-	P	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_01780	2.47e-101	-	-	-	-	-	-	-	-
HELMLDPP_01781	0.0	-	3.6.4.13	-	L	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	Belongs to the DEAD box helicase family
HELMLDPP_01782	0.0	-	-	-	E	-	-	-	COG NOG04781 non supervised orthologous group
HELMLDPP_01783	4.63e-308	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01784	0.0	cap	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HELMLDPP_01785	9.2e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HELMLDPP_01786	3.25e-274	-	-	-	L	-	-	-	Arm DNA-binding domain
HELMLDPP_01788	1.22e-273	lipB	2.3.1.181	-	H	ko:K03801	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
HELMLDPP_01789	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG COG1022 Long-chain acyl-CoA synthetases (AMP-forming)
HELMLDPP_01790	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase, FAD-containing subunit
HELMLDPP_01791	3.66e-113	-	-	-	S	-	-	-	COG NOG29454 non supervised orthologous group
HELMLDPP_01792	1.43e-63	-	-	-	-	-	-	-	-
HELMLDPP_01793	9.31e-44	-	-	-	-	-	-	-	-
HELMLDPP_01795	3.86e-270	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01796	0.0	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
HELMLDPP_01797	9.46e-200	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_01798	9.33e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_01799	3.24e-310	-	-	-	S	-	-	-	CarboxypepD_reg-like domain
HELMLDPP_01800	2.33e-35	-	-	-	S	-	-	-	COG NOG17292 non supervised orthologous group
HELMLDPP_01801	4.73e-216	-	-	-	O	-	-	-	SPFH Band 7 PHB domain protein
HELMLDPP_01803	0.0	-	-	-	L	-	-	-	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HELMLDPP_01804	2.17e-147	yciO	-	-	J	-	-	-	Belongs to the SUA5 family
HELMLDPP_01805	1.05e-188	mscS	-	-	M	ko:K03442	-	ko00000,ko02000	Small-conductance mechanosensitive channel
HELMLDPP_01806	2.11e-293	fprA	1.6.3.4	-	C	ko:K22405	-	ko00000,ko01000	anaerobic nitric oxide reductase flavorubredoxin
HELMLDPP_01807	3.27e-228	-	-	-	S	ko:K07139	-	ko00000	radical SAM protein, TIGR01212 family
HELMLDPP_01808	0.0	dpp	3.4.14.5	-	EU	ko:K01278	ko04974,map04974	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	Peptidase, S9A B C family, catalytic domain protein
HELMLDPP_01809	2.98e-212	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HELMLDPP_01810	2.59e-231	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01811	2.4e-166	rsmI_1	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Psort location Cytoplasmic, score 8.96
HELMLDPP_01812	3.63e-249	-	-	-	O	-	-	-	Zn-dependent protease
HELMLDPP_01813	1.84e-202	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HELMLDPP_01814	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_01815	1.84e-303	-	-	-	O	-	-	-	Domain of unknown function (DUF4861)
HELMLDPP_01816	0.0	xynB_10	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_01817	5.93e-119	-	-	-	K	ko:K03088	-	ko00000,ko03021	helix_turn_helix, Lux Regulon
HELMLDPP_01818	2.6e-278	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_01819	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HELMLDPP_01820	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01821	4.37e-287	-	-	-	M	-	-	-	Protein of unknown function, DUF255
HELMLDPP_01822	0.0	-	-	-	CO	-	-	-	Redoxin
HELMLDPP_01823	4.02e-281	-	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
HELMLDPP_01824	0.0	cfiA	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
HELMLDPP_01825	2.4e-32	-	4.1.1.3	-	C	ko:K01573	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	Sodium pump decarboxylase gamma subunit
HELMLDPP_01826	4.07e-122	-	-	-	C	-	-	-	Nitroreductase family
HELMLDPP_01827	4.87e-155	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HELMLDPP_01828	1.24e-232	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HELMLDPP_01829	1.87e-97	-	-	-	S	ko:K15977	-	ko00000	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_01830	2.52e-239	-	-	-	P	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01831	1.45e-193	-	-	-	P	-	-	-	ATP-binding protein involved in virulence
HELMLDPP_01832	1.58e-210	-	-	-	EG	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01833	1.2e-203	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HELMLDPP_01834	1.64e-301	-	-	-	C	-	-	-	Oxidoreductase, FAD FMN-binding protein
HELMLDPP_01835	1.7e-187	-	1.3.1.22	-	S	ko:K12343	ko00140,map00140	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01836	6.06e-164	-	-	-	S	-	-	-	AAA ATPase domain
HELMLDPP_01837	2.79e-123	-	-	-	S	-	-	-	AAA ATPase domain
HELMLDPP_01838	1.42e-211	-	2.1.1.72	-	H	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	D12 class N6 adenine-specific DNA methyltransferase
HELMLDPP_01839	0.0	-	-	-	K	-	-	-	DNA binding
HELMLDPP_01840	5.45e-236	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01841	4.24e-93	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HELMLDPP_01842	0.0	prpC	2.3.3.1, 2.3.3.5	-	C	ko:K01647,ko:K01659	ko00020,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01843	6.12e-279	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01844	0.0	acnA	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_01845	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01846	6.98e-78	-	-	-	S	-	-	-	thioesterase family
HELMLDPP_01847	1.04e-214	-	-	-	S	-	-	-	COG NOG14441 non supervised orthologous group
HELMLDPP_01848	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	COG0550 Topoisomerase IA
HELMLDPP_01849	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family
HELMLDPP_01850	2.68e-161	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01851	2.12e-125	rpoE	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_01852	4.84e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF5056)
HELMLDPP_01853	9.92e-201	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HELMLDPP_01854	1.54e-116	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HELMLDPP_01855	3.02e-111	asnC	-	-	K	ko:K03718	-	ko00000,ko03000	Transcriptional regulator
HELMLDPP_01856	0.0	-	-	-	S	-	-	-	IgA Peptidase M64
HELMLDPP_01857	8.07e-128	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01858	7.46e-101	-	-	-	U	ko:K03559	-	ko00000,ko02000	COG NOG14448 non supervised orthologous group
HELMLDPP_01859	1.29e-126	-	-	-	U	-	-	-	COG NOG14449 non supervised orthologous group
HELMLDPP_01860	8.76e-99	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01861	3.62e-170	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
HELMLDPP_01863	7.18e-186	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HELMLDPP_01864	7.21e-236	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HELMLDPP_01865	7.09e-153	-	-	-	U	ko:K03832	-	ko00000,ko02000	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HELMLDPP_01866	8.99e-157	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HELMLDPP_01867	2.86e-212	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HELMLDPP_01868	1.02e-231	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HELMLDPP_01869	2.42e-261	argK	-	-	E	ko:K07588	-	ko00000,ko01000	Lao Ao transport system ATPase
HELMLDPP_01870	4.13e-254	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HELMLDPP_01871	3.64e-108	-	-	-	-	-	-	-	-
HELMLDPP_01872	0.0	-	-	-	S	-	-	-	COG2373 Large extracellular alpha-helical protein
HELMLDPP_01873	1.9e-229	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	HipA-like C-terminal domain
HELMLDPP_01874	2.56e-76	-	2.7.11.1	-	S	ko:K07154	-	ko00000,ko01000,ko01001,ko02048	domain protein
HELMLDPP_01875	4.22e-41	-	-	-	K	-	-	-	transcriptional regulator, y4mF family
HELMLDPP_01876	3.04e-105	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Cytidine and deoxycytidylate deaminase zinc-binding region
HELMLDPP_01877	0.0	pepD_2	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Xaa-His dipeptidase
HELMLDPP_01878	3.19e-239	-	-	-	S	ko:K07027	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_01879	2.42e-200	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HELMLDPP_01880	5.12e-288	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HELMLDPP_01881	0.0	-	-	-	A	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01883	3.66e-82	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HELMLDPP_01884	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HELMLDPP_01885	8.75e-198	cdsA	2.7.7.41	-	M	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HELMLDPP_01886	2.14e-176	-	-	-	S	-	-	-	NigD-like N-terminal OB domain
HELMLDPP_01887	1.23e-277	lpxB	2.4.1.182	GT19	M	ko:K00748	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HELMLDPP_01888	5.95e-194	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HELMLDPP_01889	6.81e-174	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain
HELMLDPP_01890	5.88e-201	parB	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HELMLDPP_01891	4.15e-172	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01892	1.27e-309	mltD	-	-	M	ko:K08307	-	ko00000,ko01000,ko01011	Transglycosylase SLT domain
HELMLDPP_01893	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HELMLDPP_01894	2.84e-75	ycgE	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01895	1.1e-233	-	-	-	M	-	-	-	Peptidase, M23
HELMLDPP_01896	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HELMLDPP_01897	0.0	recD2_2	3.1.11.5	-	L	ko:K01144	-	ko00000,ko01000	COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member
HELMLDPP_01898	1.9e-162	-	-	-	S	-	-	-	COG NOG19144 non supervised orthologous group
HELMLDPP_01899	2.25e-201	-	-	-	S	-	-	-	Protein of unknown function (DUF3822)
HELMLDPP_01900	1.38e-132	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HELMLDPP_01901	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HELMLDPP_01902	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01903	3.46e-94	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_01904	2.71e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HELMLDPP_01905	2.53e-205	thiD	2.7.1.49, 2.7.4.7	-	K	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	transcriptional regulator (AraC family)
HELMLDPP_01907	9.17e-70	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein, HigA
HELMLDPP_01908	3.08e-72	-	-	-	S	ko:K07334	-	ko00000,ko02048	Plasmid maintenance system killer protein
HELMLDPP_01909	1.28e-135	-	-	-	-	-	-	-	-
HELMLDPP_01910	1.35e-175	-	-	-	L	-	-	-	Helix-turn-helix domain
HELMLDPP_01911	1.55e-103	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01912	2.14e-170	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01913	3.63e-127	-	-	-	S	-	-	-	Sel1 repeat
HELMLDPP_01914	1.69e-243	-	-	-	-	-	-	-	-
HELMLDPP_01915	6.7e-151	-	-	-	-	-	-	-	-
HELMLDPP_01916	1.39e-185	-	-	-	L	-	-	-	Helix-turn-helix domain
HELMLDPP_01917	3.6e-306	-	-	-	L	-	-	-	Arm DNA-binding domain
HELMLDPP_01921	4.83e-155	-	-	-	-	-	-	-	-
HELMLDPP_01922	2.91e-160	-	-	-	L	-	-	-	Helix-turn-helix domain
HELMLDPP_01923	1.98e-247	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_01924	0.0	nhaS3	-	-	P	-	-	-	Sodium/hydrogen exchanger family
HELMLDPP_01925	3.4e-255	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HELMLDPP_01926	1.44e-185	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HELMLDPP_01927	3.17e-187	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HELMLDPP_01928	6.89e-258	fbaB	4.1.2.13	-	G	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes
HELMLDPP_01929	7.11e-294	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HELMLDPP_01930	1.98e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01931	6.34e-193	znuB	-	-	P	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HELMLDPP_01932	3.99e-96	yjeE	-	-	S	ko:K06925	-	ko00000,ko03016	Psort location Cytoplasmic, score
HELMLDPP_01933	3.14e-41	-	-	-	S	-	-	-	COG NOG34862 non supervised orthologous group
HELMLDPP_01934	0.0	-	-	-	K	-	-	-	Plasmid pRiA4b ORF-3-like protein
HELMLDPP_01935	5.18e-76	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01936	1.94e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HELMLDPP_01937	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III alpha subunit
HELMLDPP_01938	2.7e-162	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HELMLDPP_01939	1.09e-160	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HELMLDPP_01940	1.05e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF4834)
HELMLDPP_01941	7.09e-101	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HELMLDPP_01942	2.45e-58	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01943	3.11e-84	-	-	-	L	ko:K07460	-	ko00000	Belongs to the UPF0102 family
HELMLDPP_01944	1.75e-84	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01945	4.85e-183	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	biotin acetyl-CoA-carboxylase ligase
HELMLDPP_01946	0.0	-	-	-	M	-	-	-	peptidase S41
HELMLDPP_01947	4.05e-310	dinF	-	-	V	ko:K03327	-	ko00000,ko02000	MATE efflux family protein
HELMLDPP_01948	7.4e-164	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HELMLDPP_01949	0.0	-	3.2.1.172	GH105	E	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HELMLDPP_01950	0.0	-	-	-	G	-	-	-	COG NOG26513 non supervised orthologous group
HELMLDPP_01951	0.0	-	-	-	G	-	-	-	Domain of unknown function (DUF4450)
HELMLDPP_01952	1.52e-120	-	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Phosphoglycerate mutase family
HELMLDPP_01953	2.37e-124	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HELMLDPP_01955	1.62e-229	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HELMLDPP_01956	8.05e-261	-	-	-	M	-	-	-	Peptidase, M28 family
HELMLDPP_01957	7.32e-248	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_01958	0.0	bepE_4	-	-	V	ko:K03296,ko:K18138	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_01959	4.81e-310	tolC	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_01960	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
HELMLDPP_01961	0.0	-	3.2.1.50	-	G	ko:K01205	ko00531,ko01100,ko04142,map00531,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko04147	Alpha-N-acetylglucosaminidase
HELMLDPP_01962	0.0	fumB	4.2.1.2	-	C	ko:K01676	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HELMLDPP_01963	0.0	-	-	-	S	ko:K06978	-	ko00000	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain
HELMLDPP_01964	0.0	-	-	-	JM	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_01965	3.1e-288	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HELMLDPP_01966	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01967	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01968	1.75e-184	-	-	-	-	-	-	-	-
HELMLDPP_01969	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01970	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01971	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01972	2.41e-264	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01973	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01974	1.32e-238	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01977	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HELMLDPP_01978	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_01979	8.45e-93	-	-	-	G	-	-	-	CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HELMLDPP_01980	0.0	-	4.2.2.6	-	U	ko:K01730	ko00040,map00040	ko00000,ko00001,ko01000	Oligogalacturonate lyase
HELMLDPP_01981	0.0	-	-	-	P	-	-	-	Arylsulfatase
HELMLDPP_01982	0.0	-	-	-	G	-	-	-	alpha-L-rhamnosidase
HELMLDPP_01983	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_01984	0.0	-	4.2.2.23	PL11	S	ko:K18197	-	ko00000,ko01000	FG-GAP repeat protein
HELMLDPP_01985	0.0	-	-	-	E	-	-	-	GDSL-like protein
HELMLDPP_01986	0.0	-	-	-	-	-	-	-	-
HELMLDPP_01987	4.23e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	sigma70 factor
HELMLDPP_01988	7.26e-236	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_01989	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_01990	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_01991	0.0	-	-	-	O	-	-	-	Pectic acid lyase
HELMLDPP_01992	0.0	-	-	-	G	-	-	-	hydrolase, family 65, central catalytic
HELMLDPP_01993	0.0	-	-	-	G	-	-	-	COG NOG26513 non supervised orthologous group
HELMLDPP_01994	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HELMLDPP_01995	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_01996	0.0	-	4.2.2.23	PL11	E	ko:K18197	-	ko00000,ko01000	FG-GAP repeat protein
HELMLDPP_01997	0.0	yteR_9	-	-	E	-	-	-	Glycosyl Hydrolase Family 88
HELMLDPP_01998	7.29e-75	rhaU	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HELMLDPP_01999	0.0	-	-	-	T	-	-	-	Response regulator receiver domain
HELMLDPP_02001	8.07e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HELMLDPP_02002	7.71e-182	ushA	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	5'-nucleotidase, C-terminal domain
HELMLDPP_02003	5.76e-208	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Ser Thr phosphatase family protein
HELMLDPP_02004	0.0	nagA	-	-	G	-	-	-	b-glycosidase, glycoside hydrolase family 3 protein
HELMLDPP_02005	3.31e-20	-	-	-	C	-	-	-	4Fe-4S binding domain
HELMLDPP_02006	1.86e-288	aspC	2.6.1.1	-	E	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	COG0436 Aspartate tyrosine aromatic aminotransferase
HELMLDPP_02007	1.49e-293	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HELMLDPP_02008	0.0	-	-	-	S	ko:K07091	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Permease, YjgP YjgQ family
HELMLDPP_02009	4.14e-90	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02010	0.0	wcaJ_2	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	Psort location CytoplasmicMembrane, score
HELMLDPP_02012	8.66e-57	-	-	-	S	-	-	-	2TM domain
HELMLDPP_02013	2.97e-136	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02014	1.55e-61	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HELMLDPP_02015	7.88e-244	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the LDH MDH superfamily
HELMLDPP_02016	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HELMLDPP_02017	1.79e-138	folE	3.5.4.16	-	F	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase I
HELMLDPP_02018	1.92e-102	-	-	-	S	-	-	-	Sporulation and cell division repeat protein
HELMLDPP_02019	7.41e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HELMLDPP_02020	0.0	doxX	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02021	5.23e-125	-	-	-	S	-	-	-	COG NOG27206 non supervised orthologous group
HELMLDPP_02022	2.35e-210	mepM_1	-	-	M	-	-	-	Peptidase, M23
HELMLDPP_02023	1.7e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Nucleoside diphosphate kinase
HELMLDPP_02024	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HELMLDPP_02025	2.82e-155	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HELMLDPP_02026	1.88e-124	thiJ	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1 family
HELMLDPP_02027	1.57e-141	-	-	-	M	-	-	-	TonB family domain protein
HELMLDPP_02028	6.91e-92	-	-	-	U	ko:K03559	-	ko00000,ko02000	Transport energizing protein, ExbD TolR family
HELMLDPP_02029	1.23e-163	exbB	-	-	U	ko:K03561	-	ko00000,ko02000	MotA TolQ ExbB proton channel family
HELMLDPP_02030	1.45e-171	pdxJ	2.6.99.2	-	H	ko:K03474	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HELMLDPP_02031	2.35e-210	nadK	2.7.1.23	-	H	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HELMLDPP_02032	0.0	-	-	-	NU	-	-	-	Lipid A 3-O-deacylase (PagL)
HELMLDPP_02033	9.55e-111	-	-	-	-	-	-	-	-
HELMLDPP_02034	4.14e-55	-	-	-	-	-	-	-	-
HELMLDPP_02035	1.17e-46	-	-	-	S	-	-	-	Winged helix-turn-helix domain (DUF2582)
HELMLDPP_02037	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HELMLDPP_02038	1.36e-287	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HELMLDPP_02040	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
HELMLDPP_02041	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02042	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02043	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
HELMLDPP_02044	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 35 family
HELMLDPP_02045	0.0	-	-	-	G	-	-	-	Carbohydrate binding domain protein
HELMLDPP_02046	0.0	-	-	-	G	-	-	-	hydrolase, family 43
HELMLDPP_02047	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HELMLDPP_02048	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02049	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02050	1.68e-224	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
HELMLDPP_02051	2.67e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, Bacteroides expansion family 1
HELMLDPP_02052	0.0	uvrD2	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02053	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02054	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02055	1.05e-257	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02056	3.49e-298	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HELMLDPP_02057	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HELMLDPP_02058	0.0	-	-	-	K	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02059	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02060	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HELMLDPP_02061	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02063	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02064	8.97e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02065	0.0	-	-	-	O	-	-	-	protein conserved in bacteria
HELMLDPP_02066	0.0	-	-	-	S	-	-	-	COG NOG19133 non supervised orthologous group
HELMLDPP_02067	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HELMLDPP_02068	2.62e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02069	3.5e-171	dacA	-	-	S	-	-	-	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HELMLDPP_02070	2.37e-251	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HELMLDPP_02071	1.55e-222	-	-	-	S	ko:K01163	-	ko00000	Conserved protein
HELMLDPP_02072	3.6e-148	lrgB	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02073	3.29e-75	lrgA	-	-	S	ko:K06518	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_02074	1.83e-235	pta	2.3.1.8	-	C	ko:K00625,ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_02075	2.59e-270	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HELMLDPP_02076	1.03e-193	lpxH	3.6.1.54	-	S	ko:K03269	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Psort location Cytoplasmic, score
HELMLDPP_02077	1.58e-70	yitW	-	-	S	-	-	-	FeS assembly SUF system protein
HELMLDPP_02078	1.69e-161	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HELMLDPP_02079	1.65e-243	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_02080	4.61e-132	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HELMLDPP_02081	1.39e-26	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
HELMLDPP_02082	0.0	atsB	-	-	C	ko:K06871	-	ko00000	COG0641 Arylsulfatase regulator (Fe-S oxidoreductase)
HELMLDPP_02083	1.68e-276	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HELMLDPP_02085	2.6e-184	phoN	3.1.3.2	-	I	ko:K09474	ko00740,ko01100,ko02020,map00740,map01100,map02020	ko00000,ko00001,ko01000	Acid phosphatase homologues
HELMLDPP_02086	0.0	-	-	-	-	-	-	-	-
HELMLDPP_02087	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HELMLDPP_02088	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HELMLDPP_02089	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HELMLDPP_02090	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_02091	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02092	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02093	0.0	xynB	-	-	I	-	-	-	pectin acetylesterase
HELMLDPP_02094	0.0	-	-	-	T	-	-	-	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HELMLDPP_02095	2.52e-51	-	-	-	S	-	-	-	RNA recognition motif
HELMLDPP_02096	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02097	6.66e-151	spk1	2.7.11.1, 6.3.2.4	-	S	ko:K01921,ko:K08884,ko:K12132	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01001,ko01011	PASTA domain protein
HELMLDPP_02098	6.49e-271	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HELMLDPP_02099	2.33e-236	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HELMLDPP_02100	5.27e-282	-	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02101	1.91e-156	-	-	-	S	-	-	-	COG NOG31798 non supervised orthologous group
HELMLDPP_02102	7.94e-90	glpE	-	-	P	-	-	-	Rhodanese-like protein
HELMLDPP_02103	1.35e-238	argF	2.1.3.11, 2.1.3.9	-	E	ko:K09065,ko:K13043	ko00220,ko01100,ko01230,map00220,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HELMLDPP_02104	1.53e-304	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HELMLDPP_02105	1.44e-255	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HELMLDPP_02106	4e-189	-	-	-	S	-	-	-	of the HAD superfamily
HELMLDPP_02107	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HELMLDPP_02108	2.59e-28	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
HELMLDPP_02109	1.02e-175	-	-	-	S	-	-	-	ATPase domain predominantly from Archaea
HELMLDPP_02110	2.23e-149	-	-	-	-	-	-	-	-
HELMLDPP_02111	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02112	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HELMLDPP_02113	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02114	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02115	0.0	-	-	-	S	-	-	-	PS-10 peptidase S37
HELMLDPP_02116	2.35e-157	-	-	-	S	-	-	-	COG NOG23394 non supervised orthologous group
HELMLDPP_02117	1.43e-130	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Conserved protein
HELMLDPP_02118	9.33e-48	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02119	3.32e-141	-	-	-	M	-	-	-	COG NOG27749 non supervised orthologous group
HELMLDPP_02120	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HELMLDPP_02121	3.04e-172	-	-	-	E	ko:K04477	-	ko00000	PHP domain protein
HELMLDPP_02122	5.25e-111	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HELMLDPP_02123	0.0	-	-	-	S	ko:K07037	-	ko00000	7TM receptor with intracellular HD hydrolase
HELMLDPP_02124	0.0	gltX	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HELMLDPP_02125	4.72e-307	waaA	2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15	GT30	M	ko:K02527	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	Psort location Cytoplasmic, score 8.96
HELMLDPP_02126	4.78e-110	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_02127	0.0	-	-	-	D	-	-	-	Domain of unknown function
HELMLDPP_02128	1.99e-159	-	-	-	-	-	-	-	-
HELMLDPP_02129	1.31e-212	-	-	-	S	-	-	-	Cupin
HELMLDPP_02130	8.44e-201	-	-	-	M	-	-	-	NmrA-like family
HELMLDPP_02131	7.05e-72	-	-	-	S	-	-	-	transposase or invertase
HELMLDPP_02132	3.68e-255	argE	3.5.1.16	-	E	ko:K01438	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related
HELMLDPP_02133	0.0	fadD	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme
HELMLDPP_02134	3.46e-264	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HELMLDPP_02135	3.57e-19	-	-	-	-	-	-	-	-
HELMLDPP_02136	1.5e-110	cyaA	4.6.1.1	-	S	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02137	0.0	-	-	-	M	-	-	-	TonB-dependent receptor
HELMLDPP_02138	4.75e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_02139	1.28e-93	fjo27	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_02140	0.0	-	-	-	P	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HELMLDPP_02141	3.22e-215	comEA	-	-	L	-	-	-	COG COG1555 DNA uptake protein and related DNA-binding proteins
HELMLDPP_02142	0.0	-	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HELMLDPP_02143	4.24e-124	-	-	-	-	-	-	-	-
HELMLDPP_02145	2.71e-157	-	-	-	L	-	-	-	Uncharacterized conserved protein (DUF2075)
HELMLDPP_02146	1.7e-314	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HELMLDPP_02147	2.33e-202	-	-	-	K	-	-	-	Transcriptional regulator
HELMLDPP_02148	2.09e-142	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HELMLDPP_02149	1.77e-150	-	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Phosphoglycolate phosphatase
HELMLDPP_02150	1.62e-35	-	-	-	-	-	-	-	-
HELMLDPP_02151	2.1e-56	-	-	-	S	-	-	-	RteC protein
HELMLDPP_02152	1.04e-11	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_02154	3.65e-251	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HELMLDPP_02155	5.05e-192	deoD	2.4.2.1	-	F	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HELMLDPP_02156	8.26e-274	lpxK	2.7.1.130	-	F	ko:K00912	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA)
HELMLDPP_02157	0.0	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA, 67K type
HELMLDPP_02158	9.57e-145	-	-	-	S	ko:K07078	-	ko00000	oxidoreductase related to nitroreductase
HELMLDPP_02159	0.0	fkp	-	-	S	-	-	-	GHMP kinase, N-terminal domain protein
HELMLDPP_02160	1.87e-132	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HELMLDPP_02161	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HELMLDPP_02162	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_02163	2.49e-132	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_02164	0.0	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HELMLDPP_02165	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_02166	0.0	-	-	-	G	-	-	-	F5/8 type C domain
HELMLDPP_02167	0.0	-	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	Beta-galactosidase trimerisation domain
HELMLDPP_02168	3.76e-296	-	-	-	G	-	-	-	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HELMLDPP_02169	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_02170	0.0	-	4.2.2.23	PL11	S	ko:K18197	-	ko00000,ko01000	candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238
HELMLDPP_02171	0.0	-	-	-	S	-	-	-	alpha beta
HELMLDPP_02172	0.0	-	-	-	G	-	-	-	Alpha-L-rhamnosidase
HELMLDPP_02173	3.74e-73	-	-	-	-	-	-	-	-
HELMLDPP_02174	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02175	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02177	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
HELMLDPP_02178	0.0	ramA_2	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02179	2.29e-295	zraS_1	-	-	T	-	-	-	PAS domain
HELMLDPP_02180	0.0	-	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HELMLDPP_02181	5e-310	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	outer membrane efflux protein
HELMLDPP_02182	1.36e-247	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter, RND family, MFP subunit
HELMLDPP_02183	8.29e-161	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_02184	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HELMLDPP_02185	1.96e-27	-	-	-	H	ko:K02014	-	ko00000,ko02000	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_02187	2.15e-52	-	-	-	S	-	-	-	TSCPD domain
HELMLDPP_02188	7.45e-178	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HELMLDPP_02189	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HELMLDPP_02190	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HELMLDPP_02191	6.69e-200	ispE	2.7.1.148	-	F	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HELMLDPP_02192	0.0	-	-	-	L	-	-	-	DNA-dependent ATPase I and helicase II
HELMLDPP_02193	0.0	addA	-	-	L	-	-	-	Belongs to the helicase family. UvrD subfamily
HELMLDPP_02194	5.57e-306	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02195	0.0	zraR_2	-	-	T	-	-	-	COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains
HELMLDPP_02196	3.69e-129	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HELMLDPP_02198	7.4e-126	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02199	6.39e-89	-	-	-	-	-	-	-	-
HELMLDPP_02200	3.63e-46	-	-	-	-	-	-	-	-
HELMLDPP_02201	5.11e-65	-	-	-	S	-	-	-	IS66 Orf2 like protein
HELMLDPP_02203	5.6e-101	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02204	9.47e-35	-	-	-	M	-	-	-	Capsular polysaccharide synthesis protein
HELMLDPP_02207	1.28e-210	-	-	-	H	-	-	-	Flavin containing amine oxidoreductase
HELMLDPP_02209	7.89e-55	-	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HELMLDPP_02210	2.97e-122	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HELMLDPP_02212	0.0	-	-	-	EM	-	-	-	Aminotransferase
HELMLDPP_02213	3.65e-111	-	-	-	M	-	-	-	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HELMLDPP_02214	2.94e-114	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_02215	9.86e-76	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
HELMLDPP_02216	2e-91	-	-	-	S	-	-	-	slime layer polysaccharide biosynthetic process
HELMLDPP_02217	1.23e-167	-	2.4.1.304	GT26	M	ko:K21364	-	ko00000,ko01000,ko01003,ko01005	Belongs to the glycosyltransferase 26 family
HELMLDPP_02219	2.47e-218	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_02220	4.74e-290	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02221	0.0	-	3.4.15.5	-	E	ko:K01284	-	ko00000,ko01000,ko01002	Peptidase family M3
HELMLDPP_02222	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02223	6.86e-154	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	bacteriocin export ABC transporter, lactococcin 972 group
HELMLDPP_02224	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02225	2.56e-108	-	-	-	-	-	-	-	-
HELMLDPP_02226	0.0	-	3.4.13.19	-	E	ko:K01273,ko:K01274	-	ko00000,ko00537,ko01000,ko01002,ko04147	Renal dipeptidase family protein
HELMLDPP_02227	0.0	ppdK	2.7.9.1	-	G	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the PEP-utilizing enzyme family
HELMLDPP_02228	0.0	rumA	2.1.1.190	-	H	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HELMLDPP_02229	2.28e-219	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HELMLDPP_02230	0.0	pop	-	-	EU	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HELMLDPP_02231	0.0	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
HELMLDPP_02232	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HELMLDPP_02233	0.0	-	-	-	M	-	-	-	Protein of unknown function (DUF3078)
HELMLDPP_02234	1.29e-259	wecB	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HELMLDPP_02235	2.43e-144	yadS	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02236	1.66e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_02237	0.0	-	6.4.1.1	-	C	ko:K01960	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG5016 Pyruvate oxaloacetate carboxyltransferase
HELMLDPP_02238	9.21e-212	-	-	-	G	-	-	-	Protein of unknown function (DUF1460)
HELMLDPP_02239	1.69e-171	mtgA	2.4.1.129	GT51	M	ko:K03814	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HELMLDPP_02240	2.19e-130	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HELMLDPP_02241	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02242	2.21e-313	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HELMLDPP_02243	1.06e-169	-	-	-	S	-	-	-	COG NOG27381 non supervised orthologous group
HELMLDPP_02244	6.03e-145	-	-	-	S	-	-	-	COG COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HELMLDPP_02245	3.85e-108	pyrI	-	-	F	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002	Involved in allosteric regulation of aspartate carbamoyltransferase
HELMLDPP_02246	2.2e-224	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HELMLDPP_02247	0.0	mrcA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG5009 Membrane carboxypeptidase penicillin-binding protein
HELMLDPP_02248	3.31e-200	-	-	-	S	-	-	-	COG NOG24904 non supervised orthologous group
HELMLDPP_02249	1.08e-151	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02250	2.12e-187	-	-	-	K	-	-	-	methylphosphotriester-DNA alkyltransferase and transcriptional regulator (AraC XylS family)
HELMLDPP_02251	2.5e-153	tal	2.2.1.2	-	F	ko:K00616,ko:K08314	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HELMLDPP_02252	2.36e-249	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02253	5.68e-241	ybhS	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02254	0.0	-	-	-	G	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_02255	4.32e-203	-	-	-	M	ko:K01993	-	ko00000	COG COG0845 Membrane-fusion protein
HELMLDPP_02256	5.76e-303	-	-	-	MU	-	-	-	COG NOG26656 non supervised orthologous group
HELMLDPP_02257	1.4e-139	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HELMLDPP_02258	4.04e-86	folK2	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HELMLDPP_02259	3.03e-180	kdsB	2.7.7.38	-	H	ko:K00979	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HELMLDPP_02260	5.44e-315	-	-	-	S	-	-	-	Peptidase M16 inactive domain
HELMLDPP_02261	8.26e-21	-	2.7.11.1	-	S	ko:K12132	-	ko00000,ko01000,ko01001	phosphatidylinositol-4-phosphate 5-kinase family protein K00889
HELMLDPP_02262	3.29e-189	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_02263	5.71e-165	-	-	-	S	-	-	-	TIGR02453 family
HELMLDPP_02264	1.6e-98	-	-	-	G	-	-	-	Domain of unknown function (DUF386)
HELMLDPP_02265	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	1,4-alpha-glucan branching enzyme
HELMLDPP_02266	4.32e-280	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_02267	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)
HELMLDPP_02268	3.04e-156	-	3.6.3.21	-	V	ko:K02028,ko:K02068	-	ko00000,ko00002,ko01000,ko02000	ABC transporter
HELMLDPP_02269	8.27e-180	-	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02270	1.7e-63	-	-	-	-	-	-	-	-
HELMLDPP_02271	6.98e-265	yqfO	-	-	C	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HELMLDPP_02272	1.96e-124	-	-	-	S	ko:K07164	-	ko00000	Zinc ribbon domain protein
HELMLDPP_02273	5.23e-90	-	-	-	V	-	-	-	COG NOG14438 non supervised orthologous group
HELMLDPP_02274	1.7e-189	amn	3.2.2.4	-	F	ko:K01241	ko00230,map00230	ko00000,ko00001,ko01000	COG COG0775 Nucleoside phosphorylase
HELMLDPP_02275	3.58e-238	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG1466 DNA polymerase III, delta subunit
HELMLDPP_02277	4.77e-94	-	-	-	K	-	-	-	COG NOG19093 non supervised orthologous group
HELMLDPP_02278	6.41e-190	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HELMLDPP_02279	2.1e-217	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HELMLDPP_02280	1.29e-158	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HELMLDPP_02281	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HELMLDPP_02282	8.65e-205	dapA	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HELMLDPP_02283	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02284	0.0	-	-	-	J	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02285	9.84e-170	yjjG	-	-	S	ko:K07025	-	ko00000	HAD hydrolase, TIGR02254 family
HELMLDPP_02286	2.14e-121	-	-	-	S	-	-	-	Transposase
HELMLDPP_02287	9.35e-173	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HELMLDPP_02288	3.13e-150	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HELMLDPP_02289	8.31e-255	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02291	2.03e-292	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_02292	7.31e-65	-	-	-	S	-	-	-	Helix-turn-helix domain
HELMLDPP_02293	2.27e-59	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3876)
HELMLDPP_02294	1.8e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_02295	1.1e-196	-	-	-	K	-	-	-	Transcriptional regulator
HELMLDPP_02296	2.54e-122	-	-	-	C	-	-	-	Putative TM nitroreductase
HELMLDPP_02297	7.87e-144	-	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HELMLDPP_02298	3.42e-150	-	3.1.3.18, 3.6.1.1	-	S	ko:K01091,ko:K06019	ko00190,ko00630,ko01100,ko01110,ko01130,map00190,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	Phosphoglycolate phosphatase
HELMLDPP_02299	2.02e-43	-	-	-	-	-	-	-	-
HELMLDPP_02300	2.21e-72	-	-	-	S	-	-	-	Helix-turn-helix domain
HELMLDPP_02301	7.2e-123	-	-	-	-	-	-	-	-
HELMLDPP_02302	6.39e-140	-	-	-	-	-	-	-	-
HELMLDPP_02303	8.47e-278	-	-	-	T	-	-	-	Nacht domain
HELMLDPP_02304	0.0	cls	-	-	M	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HELMLDPP_02305	5.26e-234	metF	1.5.1.20	-	C	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_02306	1.18e-277	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG2812 DNA polymerase III gamma tau subunits
HELMLDPP_02307	1.09e-286	yaaT	-	-	S	-	-	-	PSP1 C-terminal domain protein
HELMLDPP_02308	1.54e-121	gldH	-	-	S	-	-	-	Gliding motility-associated lipoprotein GldH
HELMLDPP_02309	0.0	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HELMLDPP_02310	0.0	mrdA	3.4.16.4	-	M	ko:K05515	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein 2
HELMLDPP_02311	9.58e-112	mreD	-	-	S	-	-	-	rod shape-determining protein MreD
HELMLDPP_02312	8.69e-195	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HELMLDPP_02313	2.16e-240	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HELMLDPP_02314	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	bifunctional purine biosynthesis protein PurH
HELMLDPP_02315	0.0	-	-	-	U	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02316	4.69e-261	mdsC	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02317	0.0	-	-	-	E	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HELMLDPP_02318	2.6e-177	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_02319	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02320	0.0	rhgT_2	3.1.1.11	-	EG	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Extracellular, score
HELMLDPP_02321	3.9e-289	-	-	-	Q	-	-	-	COG COG1073 Hydrolases of the alpha beta superfamily
HELMLDPP_02322	0.0	-	-	-	O	-	-	-	Pectic acid lyase
HELMLDPP_02323	8.26e-116	-	-	-	S	-	-	-	Cupin domain protein
HELMLDPP_02324	0.0	-	-	-	E	-	-	-	Abhydrolase family
HELMLDPP_02325	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HELMLDPP_02326	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_02327	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_02328	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02329	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02330	2.04e-223	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_02331	3e-132	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_02332	0.0	-	-	-	G	-	-	-	Pectinesterase
HELMLDPP_02333	0.0	-	-	-	G	-	-	-	pectinesterase activity
HELMLDPP_02334	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF5060)
HELMLDPP_02335	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02336	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02337	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02338	0.0	-	-	-	G	-	-	-	Sulfatase-modifying factor enzyme 1
HELMLDPP_02340	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02341	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02342	1.98e-233	-	3.1.1.11	-	M	ko:K01051	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Pectinesterase
HELMLDPP_02343	2.36e-313	-	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HELMLDPP_02344	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02345	5.93e-236	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HELMLDPP_02346	0.0	-	-	-	P	ko:K08191	-	ko00000,ko02000	Major Facilitator Superfamily
HELMLDPP_02347	0.0	-	3.6.4.12	-	L	ko:K10742	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG COG1112 Superfamily I DNA and RNA helicases and helicase subunits
HELMLDPP_02348	5.25e-178	-	-	-	-	-	-	-	-
HELMLDPP_02349	0.0	-	-	-	G	-	-	-	Putative collagen-binding domain of a collagenase
HELMLDPP_02350	1.33e-256	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02351	0.0	-	1.2.1.21, 1.2.1.22	-	C	ko:K07248	ko00620,ko00630,ko01120,map00620,map00630,map01120	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HELMLDPP_02352	0.0	-	-	-	T	-	-	-	Y_Y_Y domain
HELMLDPP_02353	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 28
HELMLDPP_02354	2.32e-224	-	-	-	O	-	-	-	protein conserved in bacteria
HELMLDPP_02355	1.19e-217	-	-	-	G	-	-	-	Glycosyl Hydrolase Family 88
HELMLDPP_02356	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02357	0.0	-	-	-	P	-	-	-	TonB dependent receptor
HELMLDPP_02358	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02359	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Beta galactosidase small chain
HELMLDPP_02360	2.43e-306	-	-	-	O	-	-	-	protein conserved in bacteria
HELMLDPP_02361	1.18e-295	-	-	-	G	-	-	-	Glycosyl Hydrolase Family 88
HELMLDPP_02362	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_02363	7.03e-251	xynBA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02364	0.0	-	-	-	KT	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_02365	0.0	-	-	-	G	-	-	-	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HELMLDPP_02366	2.52e-224	-	-	-	F	ko:K21572	-	ko00000,ko02000	PFAM RagB SusD
HELMLDPP_02367	0.0	-	-	-	H	-	-	-	PFAM TonB-dependent Receptor Plug
HELMLDPP_02368	7.67e-105	-	-	-	S	-	-	-	phosphatase activity
HELMLDPP_02369	1.88e-181	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HELMLDPP_02370	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02371	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_02372	1.17e-291	-	-	-	S	ko:K07133	-	ko00000	AAA domain
HELMLDPP_02373	0.0	-	-	-	S	-	-	-	Peptide-N-glycosidase F, N terminal
HELMLDPP_02374	6.43e-153	-	-	-	L	-	-	-	Bacterial DNA-binding protein
HELMLDPP_02376	2e-285	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HELMLDPP_02377	2.87e-270	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HELMLDPP_02378	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HELMLDPP_02379	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
HELMLDPP_02380	3.54e-39	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HELMLDPP_02381	2.73e-178	-	-	-	L	-	-	-	Domain of unknown function (DUF4357)
HELMLDPP_02382	8.92e-96	-	-	-	S	-	-	-	protein conserved in bacteria
HELMLDPP_02383	1.59e-07	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HELMLDPP_02384	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HELMLDPP_02385	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
HELMLDPP_02386	0.0	-	-	-	-	-	-	-	-
HELMLDPP_02387	3.77e-213	-	-	-	S	ko:K07017	-	ko00000	Putative esterase
HELMLDPP_02389	3.42e-97	-	-	-	V	-	-	-	MATE efflux family protein
HELMLDPP_02390	4.49e-259	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
HELMLDPP_02391	1.34e-133	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HELMLDPP_02392	4.05e-163	glcR	-	-	K	-	-	-	DeoR C terminal sensor domain
HELMLDPP_02393	4.53e-132	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HELMLDPP_02394	3.21e-139	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02395	2.86e-196	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HELMLDPP_02396	1.91e-81	-	-	-	S	-	-	-	Bacterial mobilisation protein (MobC)
HELMLDPP_02397	1.03e-217	-	-	-	L	-	-	-	DNA primase
HELMLDPP_02398	9.62e-248	-	-	-	T	-	-	-	COG NOG25714 non supervised orthologous group
HELMLDPP_02399	6.11e-54	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_02400	2.19e-134	-	-	-	-	-	-	-	-
HELMLDPP_02401	2.66e-233	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_02402	2.37e-222	-	-	-	S	ko:K03453	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02403	1.26e-285	amiA	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HELMLDPP_02404	4.54e-208	-	-	-	Q	ko:K02067	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component
HELMLDPP_02405	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HELMLDPP_02406	3.04e-177	-	1.5.1.38, 1.5.1.39	-	C	ko:K19285,ko:K19286	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Nitroreductase family
HELMLDPP_02407	0.0	nrd	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen
HELMLDPP_02408	0.0	-	-	-	M	-	-	-	protein involved in outer membrane biogenesis
HELMLDPP_02409	3.35e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HELMLDPP_02410	8.89e-214	-	-	-	L	-	-	-	DNA repair photolyase K01669
HELMLDPP_02411	1.05e-252	-	-	-	S	ko:K07011	-	ko00000	Glycosyl transferase family group 2
HELMLDPP_02412	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	Psort location Cytoplasmic, score 8.96
HELMLDPP_02413	0.0	-	6.2.1.3	-	I	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	Psort location CytoplasmicMembrane, score 9.82
HELMLDPP_02414	5.04e-22	-	-	-	-	-	-	-	-
HELMLDPP_02415	7.63e-12	-	-	-	-	-	-	-	-
HELMLDPP_02416	2.17e-09	-	-	-	-	-	-	-	-
HELMLDPP_02417	8.85e-92	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HELMLDPP_02418	8.32e-56	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HELMLDPP_02419	5.12e-73	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HELMLDPP_02420	9.21e-99	ohrR	-	-	K	-	-	-	Transcriptional regulator, MarR family
HELMLDPP_02421	1.36e-30	-	-	-	-	-	-	-	-
HELMLDPP_02422	2.57e-165	rprY	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_02423	0.0	rprX	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	two-component regulatory system, sensor kinase protein
HELMLDPP_02424	0.0	fusA2	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Psort location Cytoplasmic, score 9.26
HELMLDPP_02426	1.4e-286	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HELMLDPP_02428	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HELMLDPP_02429	2.36e-247	-	-	-	S	-	-	-	COG NOG27441 non supervised orthologous group
HELMLDPP_02430	7.47e-141	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_02431	1.16e-88	-	-	-	-	-	-	-	-
HELMLDPP_02432	1.71e-208	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_02433	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HELMLDPP_02434	4.4e-246	-	-	-	S	-	-	-	COG NOG27441 non supervised orthologous group
HELMLDPP_02435	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HELMLDPP_02436	0.0	aguA	3.2.1.139	-	G	ko:K01235	-	ko00000,ko01000	Alpha-glucuronidase
HELMLDPP_02437	0.0	-	-	-	S	-	-	-	COG NOG06097 non supervised orthologous group
HELMLDPP_02438	0.0	-	-	-	G	-	-	-	candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein
HELMLDPP_02439	7.31e-12	-	-	-	P	ko:K07214	-	ko00000	Putative esterase
HELMLDPP_02440	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02441	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02442	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02443	0.0	xylB	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02444	1.61e-256	xynB	-	-	G	-	-	-	Glycosyl hydrolases family 43
HELMLDPP_02445	2.81e-281	xynA	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Beta-xylanase
HELMLDPP_02446	0.0	gph	-	-	G	ko:K03292	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02447	9.94e-205	bglA_1	-	-	G	-	-	-	Glycosyl hydrolase family 16
HELMLDPP_02448	0.0	glmM	5.4.2.8	-	G	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02449	3.18e-148	-	-	-	S	-	-	-	COG NOG30041 non supervised orthologous group
HELMLDPP_02450	9.35e-254	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHH family
HELMLDPP_02451	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02452	1.63e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02453	2.08e-300	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_02454	2.13e-124	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_02455	1.84e-179	-	-	-	S	-	-	-	NigD-like N-terminal OB domain
HELMLDPP_02456	9.59e-220	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HELMLDPP_02457	0.0	clcB	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02458	3.49e-133	rimN	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Belongs to the SUA5 family
HELMLDPP_02459	0.0	xynB_10	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02460	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02461	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02462	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 65, N-terminal domain
HELMLDPP_02463	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02464	7.5e-283	-	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HELMLDPP_02465	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_02466	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_02467	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_02468	5.19e-251	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_02469	0.0	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02470	0.0	-	-	-	E	-	-	-	non supervised orthologous group
HELMLDPP_02471	1.09e-222	-	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HELMLDPP_02472	0.0	-	-	-	E	-	-	-	non supervised orthologous group
HELMLDPP_02473	5.96e-116	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HELMLDPP_02474	4.19e-35	-	-	-	S	-	-	-	NVEALA protein
HELMLDPP_02475	1.44e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
HELMLDPP_02476	3.36e-21	-	-	-	S	-	-	-	NVEALA protein
HELMLDPP_02478	1.64e-215	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HELMLDPP_02479	1.58e-41	-	-	-	S	-	-	-	NVEALA protein
HELMLDPP_02480	1.96e-194	-	-	-	S	-	-	-	protein BT4048 SWALL AAO79153 (EMBL AE016943) (373 aa) fasta scores E()
HELMLDPP_02481	2.81e-40	-	-	-	S	-	-	-	NVEALA protein
HELMLDPP_02482	2.93e-183	-	-	-	S	-	-	-	Transcriptional regulatory protein, C terminal
HELMLDPP_02483	2.35e-46	-	3.6.1.3	-	-	ko:K07132	-	ko00000,ko01000	-
HELMLDPP_02484	4.5e-252	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HELMLDPP_02485	0.0	-	-	-	KT	-	-	-	AraC family
HELMLDPP_02486	7.99e-181	nadX	1.4.1.21	-	S	ko:K06989	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Domain of unknown function DUF108
HELMLDPP_02487	9.6e-214	-	-	-	C	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HELMLDPP_02488	1.61e-179	-	-	-	O	ko:K05801	-	ko00000,ko03110	Psort location Cytoplasmic, score
HELMLDPP_02489	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HELMLDPP_02490	2.76e-213	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HELMLDPP_02491	6.62e-128	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02492	5.23e-151	-	-	-	E	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02493	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate
HELMLDPP_02494	0.0	-	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02495	2.78e-121	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_02496	1.21e-128	-	-	-	P	ko:K07240	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02497	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
HELMLDPP_02498	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HELMLDPP_02499	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor
HELMLDPP_02500	0.0	uvrA1	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HELMLDPP_02501	2.06e-260	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
HELMLDPP_02502	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain
HELMLDPP_02503	1.32e-112	-	-	-	MU	-	-	-	COG NOG29365 non supervised orthologous group
HELMLDPP_02504	3.54e-43	-	-	-	S	-	-	-	COG NOG34202 non supervised orthologous group
HELMLDPP_02505	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02506	0.0	yngK	-	-	S	-	-	-	lipoprotein YddW precursor K01189
HELMLDPP_02507	7.52e-284	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_02508	3.09e-267	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HELMLDPP_02509	1.03e-197	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the OMP decarboxylase family. Type 2 subfamily
HELMLDPP_02510	3.99e-297	-	-	-	S	ko:K06885	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02511	3.29e-157	lpxD	2.3.1.191	-	M	ko:K02536	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HELMLDPP_02512	0.0	fabZ	3.5.1.108, 4.2.1.59	-	IM	ko:K16363	ko00061,ko00540,ko01100,ko01212,map00061,map00540,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01005	Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis
HELMLDPP_02513	7.62e-118	lpxA	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HELMLDPP_02514	4.94e-122	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02515	6.05e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HELMLDPP_02516	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HELMLDPP_02517	2.71e-137	-	-	-	-	-	-	-	-
HELMLDPP_02518	0.0	-	-	-	CO	-	-	-	COG NOG24773 non supervised orthologous group
HELMLDPP_02519	6.41e-236	-	-	-	G	-	-	-	Kinase, PfkB family
HELMLDPP_02520	0.0	prc	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HELMLDPP_02521	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02522	0.0	-	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02523	8.7e-166	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_02524	4.37e-220	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HELMLDPP_02525	4.78e-115	-	-	-	M	ko:K11934	-	ko00000,ko02000	Outer membrane protein beta-barrel domain
HELMLDPP_02526	2.99e-103	dapH	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HELMLDPP_02527	0.0	-	3.4.11.9	-	E	ko:K01262	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HELMLDPP_02528	4.23e-33	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HELMLDPP_02529	5.52e-208	xerC	-	-	D	ko:K03733	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HELMLDPP_02530	1.39e-60	raiA	-	-	J	ko:K05808	-	ko00000,ko03009	Ribosomal subunit interface protein
HELMLDPP_02535	8.89e-290	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HELMLDPP_02537	1.4e-36	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HELMLDPP_02538	1.44e-122	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HELMLDPP_02539	7.31e-100	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HELMLDPP_02540	1.68e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HELMLDPP_02541	4.02e-116	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L10
HELMLDPP_02542	3.16e-65	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HELMLDPP_02543	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HELMLDPP_02544	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HELMLDPP_02545	1.42e-74	-	-	-	T	-	-	-	Protein of unknown function (DUF3467)
HELMLDPP_02546	4.7e-89	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HELMLDPP_02547	5.74e-100	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HELMLDPP_02548	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HELMLDPP_02549	6.63e-63	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HELMLDPP_02550	2.34e-147	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HELMLDPP_02551	6.14e-140	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HELMLDPP_02552	8.95e-61	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HELMLDPP_02553	5.06e-194	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HELMLDPP_02554	1.49e-58	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HELMLDPP_02555	5.1e-88	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HELMLDPP_02556	4.12e-169	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HELMLDPP_02557	1.88e-96	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HELMLDPP_02558	4.7e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HELMLDPP_02559	8.54e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HELMLDPP_02560	7.94e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HELMLDPP_02561	1.4e-69	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HELMLDPP_02562	1.04e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HELMLDPP_02563	1.35e-61	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HELMLDPP_02564	2.47e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HELMLDPP_02565	2.88e-131	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HELMLDPP_02566	6.5e-71	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HELMLDPP_02567	6.93e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HELMLDPP_02568	2.9e-31	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	50S ribosomal protein L30
HELMLDPP_02569	5.98e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HELMLDPP_02570	1.96e-309	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HELMLDPP_02571	1.15e-195	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HELMLDPP_02572	1.98e-44	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HELMLDPP_02573	1.06e-18	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HELMLDPP_02574	1.24e-81	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HELMLDPP_02575	1.01e-86	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HELMLDPP_02576	3.08e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HELMLDPP_02577	3.41e-232	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HELMLDPP_02578	1.63e-92	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HELMLDPP_02579	6.87e-93	-	-	-	-	-	-	-	-
HELMLDPP_02580	1.89e-122	-	-	-	S	-	-	-	COG NOG27987 non supervised orthologous group
HELMLDPP_02581	0.0	mutS_2	-	-	L	-	-	-	DNA mismatch repair protein MutS
HELMLDPP_02582	1.72e-126	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_02583	6.42e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4252)
HELMLDPP_02584	6.62e-117	-	-	-	C	-	-	-	lyase activity
HELMLDPP_02585	4.2e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_02586	1.55e-110	-	-	-	S	-	-	-	Domain of unknown function (DUF4252)
HELMLDPP_02587	1.97e-171	-	-	-	S	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HELMLDPP_02588	0.0	metZ	2.5.1.49	-	E	ko:K01740,ko:K10764	ko00270,ko00920,ko01100,map00270,map00920,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_02589	1.08e-102	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HELMLDPP_02590	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02591	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02592	4.02e-189	crnA	3.5.2.10	-	S	ko:K01470	ko00330,map00330	ko00000,ko00001,ko01000	Creatinine amidohydrolase
HELMLDPP_02593	4.2e-286	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	COG1454 Alcohol dehydrogenase class IV
HELMLDPP_02594	1.17e-248	-	-	-	M	-	-	-	Acyltransferase family
HELMLDPP_02595	1.36e-288	-	-	-	S	ko:K07148	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02596	0.0	-	-	-	IL	-	-	-	AAA domain
HELMLDPP_02597	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HELMLDPP_02598	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
HELMLDPP_02599	0.0	xylE	-	-	P	ko:K02100,ko:K03444,ko:K08138	-	ko00000,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HELMLDPP_02600	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_02601	6.16e-136	-	-	-	-	-	-	-	-
HELMLDPP_02602	1.86e-145	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG NOG32858 non supervised orthologous group
HELMLDPP_02603	1.5e-124	-	-	-	-	-	-	-	-
HELMLDPP_02606	7.14e-301	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HELMLDPP_02607	0.0	-	-	-	-	-	-	-	-
HELMLDPP_02608	5.54e-63	-	-	-	-	-	-	-	-
HELMLDPP_02609	6.56e-112	-	-	-	-	-	-	-	-
HELMLDPP_02610	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HELMLDPP_02611	4.79e-294	-	-	-	-	-	-	-	-
HELMLDPP_02612	3.46e-120	-	-	-	-	-	-	-	-
HELMLDPP_02613	0.0	-	-	-	D	-	-	-	Tape measure domain protein
HELMLDPP_02616	2.54e-122	-	-	-	-	-	-	-	-
HELMLDPP_02618	6.62e-105	-	3.1.3.41	-	-	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	-
HELMLDPP_02620	1.67e-72	-	-	-	-	-	-	-	-
HELMLDPP_02622	9.93e-307	-	-	-	-	-	-	-	-
HELMLDPP_02623	1.44e-146	-	-	-	-	-	-	-	-
HELMLDPP_02624	4.18e-114	-	-	-	-	-	-	-	-
HELMLDPP_02626	6.35e-54	-	-	-	-	-	-	-	-
HELMLDPP_02627	1e-80	-	-	-	-	-	-	-	-
HELMLDPP_02628	1.41e-36	-	-	-	-	-	-	-	-
HELMLDPP_02630	8.85e-61	-	-	-	S	-	-	-	Domain of unknown function (DUF3846)
HELMLDPP_02631	1.07e-40	-	-	-	H	-	-	-	C-5 cytosine-specific DNA methylase
HELMLDPP_02632	9.11e-134	-	-	-	H	-	-	-	C-5 cytosine-specific DNA methylase
HELMLDPP_02633	2.19e-25	-	-	-	-	-	-	-	-
HELMLDPP_02634	0.000215	-	-	-	-	-	-	-	-
HELMLDPP_02635	1.1e-60	-	-	-	-	-	-	-	-
HELMLDPP_02636	8.65e-53	-	-	-	-	-	-	-	-
HELMLDPP_02638	3.31e-190	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HELMLDPP_02639	7.37e-80	-	-	-	-	-	-	-	-
HELMLDPP_02640	0.0	-	-	-	-	-	-	-	-
HELMLDPP_02642	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HELMLDPP_02643	0.0	-	3.1.11.5	-	L	ko:K03581,ko:K07452,ko:K09384	ko03440,map03440	ko00000,ko00001,ko01000,ko02048,ko03400	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HELMLDPP_02644	2.39e-108	-	-	-	-	-	-	-	-
HELMLDPP_02645	1.04e-49	-	-	-	-	-	-	-	-
HELMLDPP_02646	8.82e-141	-	-	-	-	-	-	-	-
HELMLDPP_02647	1.96e-254	-	-	-	K	-	-	-	ParB-like nuclease domain
HELMLDPP_02648	3.64e-99	-	-	-	-	-	-	-	-
HELMLDPP_02649	7.06e-102	-	-	-	-	-	-	-	-
HELMLDPP_02650	3.86e-93	-	-	-	-	-	-	-	-
HELMLDPP_02651	2.02e-62	-	-	-	-	-	-	-	-
HELMLDPP_02652	1.81e-255	-	-	-	H	-	-	-	rRNA (adenine-C2-)-methyltransferase activity
HELMLDPP_02654	5.24e-34	-	-	-	-	-	-	-	-
HELMLDPP_02655	2.47e-184	-	-	-	K	-	-	-	KorB domain
HELMLDPP_02656	7.75e-113	-	-	-	-	-	-	-	-
HELMLDPP_02657	1.1e-59	-	-	-	-	-	-	-	-
HELMLDPP_02658	1.95e-122	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HELMLDPP_02659	6.79e-191	-	-	-	-	-	-	-	-
HELMLDPP_02660	1.19e-177	-	-	-	-	-	-	-	-
HELMLDPP_02661	5.39e-96	-	-	-	-	-	-	-	-
HELMLDPP_02662	7.42e-137	-	-	-	-	-	-	-	-
HELMLDPP_02663	7.11e-105	-	-	-	-	-	-	-	-
HELMLDPP_02664	9.07e-177	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HELMLDPP_02665	1.48e-217	-	-	-	L	ko:K07455	-	ko00000,ko03400	RecT family
HELMLDPP_02666	0.0	-	-	-	D	-	-	-	P-loop containing region of AAA domain
HELMLDPP_02667	2.14e-58	-	-	-	-	-	-	-	-
HELMLDPP_02669	7.71e-133	-	-	-	K	-	-	-	transcriptional regulator, LuxR family
HELMLDPP_02670	1.25e-51	-	-	-	-	-	-	-	-
HELMLDPP_02671	4.38e-92	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HELMLDPP_02673	2.47e-51	-	-	-	-	-	-	-	-
HELMLDPP_02675	1.65e-29	-	-	-	-	-	-	-	-
HELMLDPP_02677	0.0	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_02679	3.98e-161	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_02680	0.0	-	3.2.1.20	GH31	E	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HELMLDPP_02681	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02682	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HELMLDPP_02683	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02684	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02685	1.63e-260	-	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HELMLDPP_02686	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_02687	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Glycosyl hydrolase family 2, sugar binding domain protein
HELMLDPP_02688	9.33e-223	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
HELMLDPP_02689	0.0	-	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HELMLDPP_02690	0.0	-	-	-	G	-	-	-	Glycosyl hydrolases family 43
HELMLDPP_02691	3.21e-136	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_02692	8.51e-243	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
HELMLDPP_02693	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02694	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02695	2.21e-256	-	-	-	E	-	-	-	Prolyl oligopeptidase family
HELMLDPP_02698	0.0	-	-	-	G	-	-	-	alpha-galactosidase
HELMLDPP_02699	2.41e-188	-	-	-	K	-	-	-	COG NOG38984 non supervised orthologous group
HELMLDPP_02700	1.54e-142	-	-	-	S	-	-	-	COG NOG23385 non supervised orthologous group
HELMLDPP_02701	5.43e-288	-	-	-	V	-	-	-	COG0534 Na -driven multidrug efflux pump
HELMLDPP_02702	1.07e-202	-	-	-	-	-	-	-	-
HELMLDPP_02703	3.31e-162	aat	2.3.2.6	-	O	ko:K00684	-	ko00000,ko01000	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HELMLDPP_02704	0.0	clpA	-	-	O	ko:K03694	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HELMLDPP_02705	5.09e-63	clpS	-	-	S	ko:K06891	-	ko00000	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HELMLDPP_02706	3.55e-164	-	-	-	-	-	-	-	-
HELMLDPP_02707	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HELMLDPP_02708	1.23e-127	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_02709	1.39e-231	-	-	-	PT	-	-	-	COG3712 Fe2 -dicitrate sensor, membrane component
HELMLDPP_02710	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HELMLDPP_02711	0.0	-	-	-	G	-	-	-	Alpha-1,2-mannosidase
HELMLDPP_02712	9.31e-57	-	-	-	-	-	-	-	-
HELMLDPP_02713	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HELMLDPP_02714	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_02715	1.86e-209	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
HELMLDPP_02716	1.72e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HELMLDPP_02717	3.73e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1016)
HELMLDPP_02718	0.0	-	3.2.1.20	GH31	S	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG NOG06228 non supervised orthologous group
HELMLDPP_02719	1.25e-315	ampG	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02720	1.83e-267	-	2.4.1.319, 2.4.1.320	-	G	ko:K18785	-	ko00000,ko01000	glycosylase
HELMLDPP_02721	8.63e-131	kefF	-	-	S	ko:K11748	-	ko00000,ko02000	NADPH-quinone reductase (modulator of drug activity B)
HELMLDPP_02722	7.63e-168	-	-	-	IQ	-	-	-	KR domain
HELMLDPP_02723	2.44e-208	akr5f	-	-	S	-	-	-	aldo keto reductase family
HELMLDPP_02724	1.85e-205	yvgN	-	-	S	-	-	-	aldo keto reductase family
HELMLDPP_02725	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator
HELMLDPP_02726	6.04e-316	-	-	-	S	-	-	-	hydrolase activity, acting on glycosyl bonds
HELMLDPP_02727	1.19e-235	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_02728	2.71e-120	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily
HELMLDPP_02729	0.0	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02730	0.0	lacZ	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HELMLDPP_02731	3.01e-192	-	-	-	J	ko:K10716	-	ko00000,ko02000	Transporter, cation channel family protein
HELMLDPP_02732	1.51e-236	mltD_2	-	-	M	-	-	-	Transglycosylase SLT domain protein
HELMLDPP_02733	1.01e-221	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 9.26
HELMLDPP_02734	0.0	-	-	-	T	-	-	-	adenylate cyclase carring two-component hybrid sensor and regulator domains
HELMLDPP_02735	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02736	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02737	0.0	-	-	-	M	-	-	-	Parallel beta-helix repeats
HELMLDPP_02738	1.72e-109	-	-	-	S	-	-	-	COG NOG30135 non supervised orthologous group
HELMLDPP_02739	1.94e-198	rhaD	4.1.2.19	-	G	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	COG COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HELMLDPP_02740	1.41e-240	rhaT	-	-	EG	ko:K02856	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02741	5.39e-314	rhaA	5.3.1.14	-	G	ko:K01813	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02742	0.0	rhaB	2.7.1.5, 2.7.1.51	-	G	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HELMLDPP_02743	7.39e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HELMLDPP_02744	7.69e-134	-	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02745	3.65e-293	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate synthase
HELMLDPP_02746	8.8e-240	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HELMLDPP_02747	7.35e-272	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HELMLDPP_02748	5.59e-174	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HELMLDPP_02749	5.86e-226	-	-	-	S	-	-	-	Metalloenzyme superfamily
HELMLDPP_02750	0.0	-	-	-	S	ko:K07079	-	ko00000	of the aldo keto reductase family
HELMLDPP_02751	0.0	yccM	-	-	C	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02752	1.64e-94	-	-	-	S	-	-	-	COG COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_02753	6.31e-75	nimB	-	-	S	ko:K07005	-	ko00000	Pyridoxamine 5'-phosphate oxidase
HELMLDPP_02754	1.81e-127	-	-	-	K	-	-	-	Cupin domain protein
HELMLDPP_02755	0.0	acsA	6.2.1.1, 6.2.1.32	-	I	ko:K01895,ko:K08295	ko00010,ko00620,ko00627,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00627,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	Psort location Cytoplasmic, score
HELMLDPP_02756	6.65e-104	-	-	-	S	-	-	-	Dihydro-orotase-like
HELMLDPP_02757	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_02758	0.0	-	-	-	P	-	-	-	Psort location OuterMembrane, score
HELMLDPP_02759	0.0	-	-	-	S	-	-	-	Susd and RagB outer membrane lipoprotein
HELMLDPP_02760	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02762	0.0	-	-	-	S	-	-	-	COG NOG09947 non supervised orthologous group
HELMLDPP_02763	6.74e-69	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
HELMLDPP_02764	7.91e-69	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02765	5.34e-27	-	-	-	S	-	-	-	ORF located using Blastx
HELMLDPP_02766	1.14e-65	-	-	-	S	-	-	-	DNA binding domain, excisionase family
HELMLDPP_02767	6.36e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF2971)
HELMLDPP_02768	7.66e-71	-	-	-	S	-	-	-	COG3943, virulence protein
HELMLDPP_02769	3.06e-301	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_02770	1.98e-11	-	-	-	S	-	-	-	Aldo/keto reductase family
HELMLDPP_02771	4.69e-34	-	-	-	S	-	-	-	aldo keto reductase family
HELMLDPP_02773	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_02774	1.4e-167	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_02775	7.1e-39	-	-	-	-	-	-	-	-
HELMLDPP_02776	3.53e-07	-	-	-	-	-	-	-	-
HELMLDPP_02777	8.01e-77	-	-	-	L	-	-	-	PFAM Integrase catalytic
HELMLDPP_02779	2.95e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
HELMLDPP_02780	5.64e-255	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HELMLDPP_02781	1.18e-222	-	-	-	L	-	-	-	CHC2 zinc finger
HELMLDPP_02782	5.82e-94	-	-	-	-	-	-	-	-
HELMLDPP_02783	2.17e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF2786)
HELMLDPP_02785	1.36e-75	-	-	-	-	-	-	-	-
HELMLDPP_02786	6.01e-62	-	-	-	-	-	-	-	-
HELMLDPP_02787	2.28e-20	-	-	-	-	-	-	-	-
HELMLDPP_02788	1.98e-44	-	-	-	-	-	-	-	-
HELMLDPP_02790	5.66e-63	-	-	-	S	-	-	-	Domain of unknown function (DUF3127)
HELMLDPP_02791	7.57e-114	-	-	-	M	-	-	-	(189 aa) fasta scores E()
HELMLDPP_02792	0.0	-	-	-	M	-	-	-	chlorophyll binding
HELMLDPP_02793	7.97e-150	-	-	-	-	-	-	-	-
HELMLDPP_02794	2.66e-201	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_02795	0.0	-	-	-	S	-	-	-	Putative binding domain, N-terminal
HELMLDPP_02796	3.82e-183	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_02797	9.82e-37	-	-	-	-	-	-	-	-
HELMLDPP_02798	0.0	-	-	-	U	-	-	-	conjugation system ATPase, TraG family
HELMLDPP_02799	1.54e-100	-	-	-	-	-	-	-	-
HELMLDPP_02800	1.07e-168	-	-	-	-	-	-	-	-
HELMLDPP_02801	3.7e-212	-	-	-	S	-	-	-	Conjugative transposon, TraM
HELMLDPP_02802	1.52e-103	-	-	-	-	-	-	-	-
HELMLDPP_02804	1.21e-49	-	-	-	-	-	-	-	-
HELMLDPP_02805	3.18e-262	-	-	-	U	-	-	-	Domain of unknown function (DUF4138)
HELMLDPP_02807	1.91e-54	-	-	-	-	-	-	-	-
HELMLDPP_02808	3.73e-54	-	-	-	S	-	-	-	HTH domain
HELMLDPP_02809	2.17e-226	-	-	-	-	-	-	-	-
HELMLDPP_02811	1.52e-121	-	-	-	O	-	-	-	growth
HELMLDPP_02812	1.11e-117	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_02813	3.03e-280	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HELMLDPP_02814	7.51e-193	-	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HELMLDPP_02816	1.02e-315	-	-	-	L	-	-	-	Transposase IS66 family
HELMLDPP_02817	4.94e-75	-	-	-	S	-	-	-	IS66 Orf2 like protein
HELMLDPP_02820	8.75e-48	-	-	-	S	-	-	-	PFAM Acyltransferase family
HELMLDPP_02821	3.06e-60	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HELMLDPP_02822	2.18e-239	-	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HELMLDPP_02824	2.02e-251	kdsC	2.7.7.43, 2.7.7.92, 3.1.3.103, 3.1.3.45	-	M	ko:K03270,ko:K21055,ko:K21749	ko00520,ko00540,ko01100,map00520,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
HELMLDPP_02825	1.04e-215	neuB	2.5.1.132, 2.5.1.56	-	M	ko:K01654,ko:K21279	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02826	3.34e-13	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	serine acetyltransferase
HELMLDPP_02827	3.82e-23	MA20_17390	-	GT4	M	ko:K00713,ko:K03867,ko:K06338	-	ko00000,ko01000,ko01003,ko01005	lipopolysaccharide 3-alpha-galactosyltransferase activity
HELMLDPP_02828	3.64e-65	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_02829	1.12e-67	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HELMLDPP_02833	1.51e-42	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HELMLDPP_02834	4.64e-64	-	-	-	C	-	-	-	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
HELMLDPP_02835	4.85e-104	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HELMLDPP_02836	8.95e-203	-	-	-	V	-	-	-	COG NOG25117 non supervised orthologous group
HELMLDPP_02838	1.34e-10	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_02840	0.0	-	-	-	L	-	-	-	helicase
HELMLDPP_02841	7.94e-249	-	-	-	CO	-	-	-	Glutathione peroxidase
HELMLDPP_02842	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_02843	0.0	-	-	-	KT	-	-	-	COG NOG25147 non supervised orthologous group
HELMLDPP_02844	1.38e-82	-	-	-	K	-	-	-	Transcriptional regulator, BlaI MecI CopY family
HELMLDPP_02845	7.88e-311	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HELMLDPP_02846	0.0	xynBA	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 43 family
HELMLDPP_02847	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HELMLDPP_02848	0.0	-	-	-	-	-	-	-	-
HELMLDPP_02849	1.67e-250	-	-	-	V	-	-	-	Beta-lactamase
HELMLDPP_02850	0.0	-	-	-	D	ko:K09955	-	ko00000	protein conserved in bacteria
HELMLDPP_02851	1.54e-35	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02853	7.01e-251	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HELMLDPP_02854	1.38e-78	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_02855	8.22e-74	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor, ECF subfamily K00960
HELMLDPP_02856	5.71e-26	-	-	-	L	-	-	-	Pfam:Methyltransf_26
HELMLDPP_02857	2.16e-128	bioH	-	-	I	-	-	-	carboxylic ester hydrolase activity
HELMLDPP_02858	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_02859	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
HELMLDPP_02860	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
HELMLDPP_02861	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_02862	0.0	-	-	-	S	-	-	-	Serine hydrolase involved in the detoxification of formaldehyde
HELMLDPP_02864	2.9e-190	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HELMLDPP_02865	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_02866	1.34e-144	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HELMLDPP_02867	1.61e-107	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HELMLDPP_02868	5.23e-43	-	3.2.1.45	GH30	G	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 30 family
HELMLDPP_02869	0.0	-	-	-	G	-	-	-	Alpha-L-arabinofuranosidase C-terminal domain
HELMLDPP_02870	0.0	aglC	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	COG3345 Alpha-galactosidase
HELMLDPP_02871	2.45e-273	-	3.2.1.20	GH31	M	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HELMLDPP_02872	2.96e-106	-	-	-	G	-	-	-	myo-inosose-2 dehydratase activity
HELMLDPP_02873	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	COG NOG28394 non supervised orthologous group
HELMLDPP_02874	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02875	2.24e-117	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_02876	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
HELMLDPP_02877	0.0	-	-	-	S	-	-	-	Heparinase II/III-like protein
HELMLDPP_02878	0.0	-	-	-	S	-	-	-	Serine hydrolase involved in the detoxification of formaldehyde
HELMLDPP_02879	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	glycosyl hydrolase, family 3
HELMLDPP_02881	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 92
HELMLDPP_02882	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 C-terminal, oligomerisation
HELMLDPP_02883	2.34e-281	-	-	-	G	-	-	-	Glycosyl hydrolases family 28
HELMLDPP_02884	6.64e-277	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02885	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02886	1.1e-244	-	-	-	G	-	-	-	Fibronectin type III
HELMLDPP_02887	5.24e-235	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl-hydrolase 97 N-terminal
HELMLDPP_02888	5.41e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_02889	2.45e-310	-	3.2.1.180	GH88	S	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
HELMLDPP_02890	0.0	-	-	-	KT	-	-	-	Y_Y_Y domain
HELMLDPP_02891	0.0	-	-	-	S	-	-	-	AIPR protein
HELMLDPP_02892	1.34e-109	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
HELMLDPP_02893	2.16e-239	-	-	-	N	-	-	-	bacterial-type flagellum assembly
HELMLDPP_02894	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	N-6 DNA methylase
HELMLDPP_02895	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related
HELMLDPP_02896	3.3e-39	-	-	-	K	-	-	-	DNA-binding helix-turn-helix protein
HELMLDPP_02897	2.11e-140	-	-	-	-	-	-	-	-
HELMLDPP_02898	2.75e-217	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_02899	3.05e-153	-	-	-	K	-	-	-	Transcription termination factor nusG
HELMLDPP_02900	1.3e-234	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_02901	5.93e-287	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HELMLDPP_02902	1.02e-267	-	-	-	M	-	-	-	Glycosyl transferase 4-like
HELMLDPP_02903	5.47e-301	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_02904	1.61e-251	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_02905	6.29e-268	-	-	-	-	-	-	-	-
HELMLDPP_02906	1.82e-253	-	-	-	S	-	-	-	Acyltransferase family
HELMLDPP_02907	2.42e-314	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HELMLDPP_02908	0.0	-	-	-	C	-	-	-	coenzyme F420-reducing hydrogenase beta subunit
HELMLDPP_02909	4.71e-287	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
HELMLDPP_02910	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02911	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02912	3.58e-142	-	-	-	I	-	-	-	PAP2 family
HELMLDPP_02913	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	Pfam:DUF303
HELMLDPP_02914	5.7e-196	-	2.7.1.33	-	H	ko:K09680	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenate kinase
HELMLDPP_02915	4.07e-122	-	-	-	I	-	-	-	NUDIX domain
HELMLDPP_02916	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
HELMLDPP_02917	6.11e-135	fchA	-	-	E	-	-	-	COG3404 Methenyl tetrahydrofolate cyclohydrolase
HELMLDPP_02918	4.51e-300	hutI	3.5.2.7	-	F	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
HELMLDPP_02919	8.25e-218	ftcD	2.1.2.5, 4.3.1.4	-	E	ko:K00603,ko:K13990	ko00340,ko00670,ko01100,map00340,map00670,map01100	ko00000,ko00001,ko01000,ko03036,ko04147	Glutamate formiminotransferase
HELMLDPP_02920	0.0	hutU	4.2.1.49	-	H	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HELMLDPP_02921	5.59e-249	-	-	-	K	-	-	-	WYL domain
HELMLDPP_02922	0.0	-	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
HELMLDPP_02923	1.59e-266	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02924	5.58e-184	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HELMLDPP_02925	0.0	-	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	HsdM N-terminal domain
HELMLDPP_02926	4.49e-300	queA	2.4.99.17	-	H	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HELMLDPP_02927	2.79e-254	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_02928	3.2e-91	paaI	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	phenylacetic acid degradation protein
HELMLDPP_02929	5.98e-144	-	4.1.1.22	-	E	ko:K01590	ko00340,ko01100,ko01110,map00340,map01100,map01110	ko00000,ko00001,ko01000	Histidine carboxylase PI chain
HELMLDPP_02930	0.0	acd	-	-	C	-	-	-	Acyl-CoA dehydrogenase, C-terminal domain
HELMLDPP_02931	7.59e-245	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Psort location Cytoplasmic, score 8.96
HELMLDPP_02932	5.53e-210	etfB	-	-	C	ko:K03521	-	ko00000	COG2086 Electron transfer flavoprotein beta subunit
HELMLDPP_02933	1.35e-55	-	-	-	S	-	-	-	NVEALA protein
HELMLDPP_02934	1.05e-37	-	-	-	S	-	-	-	TolB-like 6-blade propeller-like
HELMLDPP_02935	6.84e-121	-	-	-	-	-	-	-	-
HELMLDPP_02936	0.0	-	-	-	M	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HELMLDPP_02937	6.21e-265	-	-	-	M	-	-	-	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_02938	0.0	bpeF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_02939	3.09e-287	ybdG_2	-	-	M	ko:K16053	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score
HELMLDPP_02940	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_02941	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02942	3.12e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HELMLDPP_02943	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02944	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02945	0.0	mutB	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02946	0.0	mutA	5.4.99.2	-	I	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	methylmalonyl-CoA mutase small subunit
HELMLDPP_02947	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02948	0.0	-	-	-	S	ko:K06158	-	ko00000,ko03012	Psort location CytoplasmicMembrane, score
HELMLDPP_02949	9.98e-134	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase
HELMLDPP_02950	3.18e-236	-	-	-	PT	-	-	-	Domain of unknown function (DUF4974)
HELMLDPP_02951	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02952	0.0	-	-	-	GM	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_02953	0.0	-	-	GH63	G	ko:K03931	-	ko00000	Glycoside hydrolase
HELMLDPP_02954	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	COG3250 Beta-galactosidase beta-glucuronidase
HELMLDPP_02955	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_02956	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_02957	9.16e-289	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HELMLDPP_02958	5.36e-122	-	-	-	S	ko:K07095	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_02959	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HELMLDPP_02961	1.59e-65	-	-	-	H	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02962	9.29e-148	-	-	-	V	-	-	-	Peptidase C39 family
HELMLDPP_02963	0.0	-	-	-	C	-	-	-	Iron-sulfur cluster-binding domain
HELMLDPP_02964	5.5e-42	-	-	-	-	-	-	-	-
HELMLDPP_02965	1.83e-280	-	-	-	V	-	-	-	HlyD family secretion protein
HELMLDPP_02966	9.26e-60	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_02967	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_02968	8.61e-222	-	-	-	-	-	-	-	-
HELMLDPP_02969	2.18e-51	-	-	-	-	-	-	-	-
HELMLDPP_02970	6.19e-94	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
HELMLDPP_02971	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_02972	4.38e-166	-	-	-	S	-	-	-	Radical SAM superfamily
HELMLDPP_02973	2.06e-85	-	-	-	-	-	-	-	-
HELMLDPP_02976	8.03e-278	-	-	-	C	ko:K06871	-	ko00000	radical SAM domain protein
HELMLDPP_02977	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02978	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02979	1.05e-51	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02980	0.0	-	-	-	P	-	-	-	Outer membrane protein beta-barrel family
HELMLDPP_02981	3.78e-148	-	-	-	V	-	-	-	Peptidase C39 family
HELMLDPP_02982	4.11e-223	-	-	-	-	-	-	-	-
HELMLDPP_02983	3.76e-89	-	-	-	S	-	-	-	Domain of unknown function (DUF3244)
HELMLDPP_02984	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_02985	1.16e-149	-	-	-	F	-	-	-	Cytidylate kinase-like family
HELMLDPP_02986	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02987	0.0	aprN	-	-	M	-	-	-	Belongs to the peptidase S8 family
HELMLDPP_02988	2.35e-253	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HELMLDPP_02989	8.52e-37	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HELMLDPP_02990	3.54e-259	ilvE	2.6.1.42	-	EH	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase
HELMLDPP_02991	6.14e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HELMLDPP_02992	8.77e-189	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HELMLDPP_02993	9.11e-260	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HELMLDPP_02994	0.0	-	-	-	U	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HELMLDPP_02995	7.06e-81	-	-	-	K	-	-	-	Transcriptional regulator
HELMLDPP_02996	4.3e-96	nlpE	-	-	MP	-	-	-	lipoprotein NlpE involved in copper resistance
HELMLDPP_02997	1.97e-295	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02998	4.4e-268	-	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_02999	7.23e-217	-	-	-	M	ko:K01993	-	ko00000	Auxiliary transport protein, membrane fusion protein (MFP) family protein
HELMLDPP_03000	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03001	1.97e-179	-	-	-	S	-	-	-	COG NOG11650 non supervised orthologous group
HELMLDPP_03002	1.17e-219	mdh	1.1.1.37	-	C	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible oxidation of malate to oxaloacetate
HELMLDPP_03003	0.0	-	-	-	S	-	-	-	Endonuclease Exonuclease Phosphatase
HELMLDPP_03004	1.12e-121	ibrB	-	-	K	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_03005	0.0	-	-	-	S	-	-	-	Phosphoadenosine phosphosulfate reductase family
HELMLDPP_03006	4.28e-93	-	-	-	S	-	-	-	COG NOG32529 non supervised orthologous group
HELMLDPP_03007	0.0	gdh	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HELMLDPP_03008	0.0	ppsA	-	-	GKT	-	-	-	Pyruvate phosphate dikinase, PEP pyruvate binding domain
HELMLDPP_03009	1.77e-103	-	-	-	S	-	-	-	Calycin-like beta-barrel domain
HELMLDPP_03010	7.7e-276	-	-	-	S	-	-	-	Domain of unknown function (DUF4925)
HELMLDPP_03011	7.51e-193	-	-	-	S	-	-	-	COG NOG19137 non supervised orthologous group
HELMLDPP_03012	1.07e-284	-	-	-	S	-	-	-	non supervised orthologous group
HELMLDPP_03013	0.0	gdhA	1.4.1.4	-	C	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HELMLDPP_03014	3.82e-14	-	-	-	-	-	-	-	-
HELMLDPP_03015	0.0	maeB	1.1.1.38, 1.1.1.40	-	C	ko:K00027,ko:K00029	ko00620,ko00710,ko01100,ko01120,ko01200,ko02020,map00620,map00710,map01100,map01120,map01200,map02020	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03016	3.15e-278	mtrC	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_03017	0.0	mexF	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_03018	0.0	-	-	-	MU	-	-	-	Efflux transporter, outer membrane factor lipoprotein, NodT family
HELMLDPP_03019	2.08e-129	lpxA2	2.3.1.129	-	M	ko:K00677	ko00540,ko01100,ko01503,map00540,map01100,map01503	ko00000,ko00001,ko00002,ko01000,ko01005	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HELMLDPP_03020	2.41e-149	-	-	-	K	-	-	-	transcriptional regulator, TetR family
HELMLDPP_03021	2.35e-302	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03022	1.7e-237	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_03023	0.0	czcA	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_03024	1.86e-67	-	-	-	E	-	-	-	COG NOG19114 non supervised orthologous group
HELMLDPP_03025	0.0	-	-	-	E	-	-	-	COG COG2755 Lysophospholipase L1 and related esterases
HELMLDPP_03026	1.03e-237	-	-	-	E	-	-	-	COG NOG14456 non supervised orthologous group
HELMLDPP_03027	0.0	algI	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03029	1.12e-64	-	-	-	-	-	-	-	-
HELMLDPP_03030	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	non supervised orthologous group
HELMLDPP_03031	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03032	1.38e-63	-	-	-	L	ko:K07484	-	ko00000	COG COG3436 Transposase and inactivated derivatives
HELMLDPP_03033	4.33e-137	-	-	-	L	-	-	-	Transposase IS66 family
HELMLDPP_03034	7.61e-138	-	-	-	L	-	-	-	Transposase IS66 family
HELMLDPP_03035	1.48e-45	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HELMLDPP_03036	2.79e-257	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	Reverse transcriptase (RNA-dependent DNA polymerase)
HELMLDPP_03037	7.86e-17	-	3.6.4.12	-	K	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Putative ATP-dependent DNA helicase recG C-terminal
HELMLDPP_03038	1.09e-72	-	-	-	-	-	-	-	-
HELMLDPP_03039	1.76e-259	-	-	-	S	ko:K07504	-	ko00000	Type I restriction enzyme HsdR protein
HELMLDPP_03040	4.96e-108	-	-	-	-	-	-	-	-
HELMLDPP_03041	5.57e-141	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG NOG32858 non supervised orthologous group
HELMLDPP_03043	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HELMLDPP_03044	7.23e-93	-	-	-	-	-	-	-	-
HELMLDPP_03045	1.74e-251	-	-	-	L	-	-	-	Reverse transcriptase (RNA-dependent DNA polymerase)
HELMLDPP_03047	7.91e-83	-	-	-	-	-	-	-	-
HELMLDPP_03048	8.48e-275	-	-	-	-	-	-	-	-
HELMLDPP_03049	8.92e-122	-	-	-	-	-	-	-	-
HELMLDPP_03050	6.65e-41	-	-	-	S	-	-	-	domain, Protein
HELMLDPP_03051	1.33e-227	-	-	-	-	-	-	-	-
HELMLDPP_03052	9.69e-114	-	-	-	-	-	-	-	-
HELMLDPP_03053	0.0	-	-	-	D	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03054	4.88e-112	-	-	-	-	-	-	-	-
HELMLDPP_03055	7.23e-107	-	-	-	-	-	-	-	-
HELMLDPP_03056	3.49e-102	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03057	1.08e-96	-	3.1.3.41	-	-	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	-
HELMLDPP_03058	1.46e-71	-	-	-	-	-	-	-	-
HELMLDPP_03059	9.35e-74	-	-	-	-	-	-	-	-
HELMLDPP_03060	4.18e-261	-	-	-	S	-	-	-	Phage major capsid protein E
HELMLDPP_03061	1.87e-132	-	-	-	-	-	-	-	-
HELMLDPP_03062	3.18e-149	-	-	-	-	-	-	-	-
HELMLDPP_03064	1.04e-49	-	-	-	-	-	-	-	-
HELMLDPP_03067	7.28e-266	-	-	-	-	-	-	-	-
HELMLDPP_03069	1.56e-118	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03071	1.9e-69	-	-	-	S	ko:K07334	-	ko00000,ko02048	Plasmid maintenance system killer protein
HELMLDPP_03072	5.12e-73	higA	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein, HigA
HELMLDPP_03074	0.0	-	-	-	K	-	-	-	cell adhesion
HELMLDPP_03075	1.64e-55	-	-	-	-	-	-	-	-
HELMLDPP_03076	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HELMLDPP_03077	0.0	-	-	-	L	-	-	-	COG COG1783 Phage terminase large subunit
HELMLDPP_03078	1.36e-126	-	-	-	-	-	-	-	-
HELMLDPP_03079	1.65e-64	-	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HELMLDPP_03080	0.0	-	-	-	S	-	-	-	DNA methylase
HELMLDPP_03081	1.92e-89	-	-	-	S	-	-	-	Protein conserved in bacteria
HELMLDPP_03082	3.89e-84	-	-	-	-	-	-	-	-
HELMLDPP_03084	8.13e-61	-	-	-	-	-	-	-	-
HELMLDPP_03088	3.01e-30	-	-	-	-	-	-	-	-
HELMLDPP_03089	3.75e-61	-	-	-	-	-	-	-	-
HELMLDPP_03092	6.32e-119	-	-	-	-	-	-	-	-
HELMLDPP_03093	0.0	-	3.6.4.12	-	L	ko:K17680	-	ko00000,ko01000,ko03029	Psort location Cytoplasmic, score 8.96
HELMLDPP_03094	1.29e-232	-	-	-	V	-	-	-	HNH endonuclease
HELMLDPP_03095	0.0	-	-	-	L	ko:K19789	-	ko00000,ko03400	helicase superfamily c-terminal domain
HELMLDPP_03097	4.01e-236	-	-	-	L	-	-	-	YqaJ-like viral recombinase domain
HELMLDPP_03099	7.21e-136	-	-	-	-	-	-	-	-
HELMLDPP_03100	3.97e-201	-	-	-	-	-	-	-	-
HELMLDPP_03101	1.74e-59	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_03105	2.69e-122	-	-	-	-	-	-	-	-
HELMLDPP_03106	1.28e-93	-	-	-	-	-	-	-	-
HELMLDPP_03107	2.46e-106	-	-	-	-	-	-	-	-
HELMLDPP_03108	1.66e-60	-	-	-	-	-	-	-	-
HELMLDPP_03109	2.17e-287	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03110	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HELMLDPP_03111	2.29e-112	msrC	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03112	4.96e-215	udp	2.4.2.3	-	F	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03113	6.64e-215	-	-	-	S	-	-	-	UPF0365 protein
HELMLDPP_03114	1.01e-99	-	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03115	0.0	-	-	-	S	-	-	-	COG NOG11656 non supervised orthologous group
HELMLDPP_03116	6.4e-176	ttcA	-	-	H	ko:K14058	-	ko00000,ko03016	Belongs to the TtcA family
HELMLDPP_03118	1.91e-10	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03119	3.13e-46	-	-	-	-	-	-	-	-
HELMLDPP_03120	1.93e-84	-	-	-	S	ko:K09922	-	ko00000	Psort location CytoplasmicMembrane, score
HELMLDPP_03121	4.49e-184	-	-	-	S	-	-	-	COG NOG28261 non supervised orthologous group
HELMLDPP_03123	0.0	gltA	1.3.1.1, 1.4.1.13, 1.4.1.14	-	C	ko:K00266,ko:K17722	ko00240,ko00250,ko00410,ko00770,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00240,map00250,map00410,map00770,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.97
HELMLDPP_03124	3.2e-284	-	-	-	G	-	-	-	Major Facilitator Superfamily
HELMLDPP_03125	2.36e-307	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Psort location Cytoplasmic, score
HELMLDPP_03126	1.13e-133	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HELMLDPP_03127	7.24e-154	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiamine diphosphokinase
HELMLDPP_03128	8.74e-57	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HELMLDPP_03129	6.75e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HELMLDPP_03130	0.0	ppaX	3.1.3.18	-	V	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant 1
HELMLDPP_03131	4.55e-121	mepS	3.4.17.13	-	M	ko:K13694	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family
HELMLDPP_03132	8.69e-167	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
HELMLDPP_03133	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03134	0.0	-	-	-	S	ko:K07263	-	ko00000,ko01000,ko01002	Belongs to the peptidase M16 family
HELMLDPP_03135	3.4e-229	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HELMLDPP_03136	1.92e-141	lolA	-	-	M	ko:K03634	-	ko00000	COG NOG19151 non supervised orthologous group
HELMLDPP_03137	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related
HELMLDPP_03138	1.49e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03139	8.74e-153	rnd	-	-	L	-	-	-	3'-5' exonuclease
HELMLDPP_03140	7.4e-298	rlmI	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	SAM-dependent
HELMLDPP_03141	8.41e-260	-	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HELMLDPP_03142	1.41e-199	-	-	-	H	-	-	-	Methyltransferase domain
HELMLDPP_03143	3e-89	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_03144	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3857)
HELMLDPP_03145	0.0	-	-	-	E	-	-	-	Domain of Unknown Function with PDB structure (DUF3858)
HELMLDPP_03146	1.35e-289	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
HELMLDPP_03147	3.83e-104	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
HELMLDPP_03148	2.1e-128	-	-	-	-	-	-	-	-
HELMLDPP_03149	1.39e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF5024)
HELMLDPP_03150	1.27e-307	nupG	-	-	G	ko:K03289,ko:K11537	-	ko00000,ko02000	transport of nucleosides, permease protein K03289
HELMLDPP_03151	2.02e-125	-	-	-	S	ko:K08999	-	ko00000	Conserved protein
HELMLDPP_03152	2.14e-166	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HELMLDPP_03153	0.0	-	-	-	S	-	-	-	COG NOG26882 non supervised orthologous group
HELMLDPP_03154	5.92e-150	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system ATPase component
HELMLDPP_03155	3.59e-283	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03156	7.82e-97	yjbQ	-	-	S	-	-	-	Secondary thiamine-phosphate synthase enzyme
HELMLDPP_03157	3.76e-151	-	-	-	-	-	-	-	-
HELMLDPP_03159	0.0	pruA	1.2.1.3, 1.2.1.88, 1.5.5.2	-	C	ko:K00128,ko:K00294,ko:K13821	ko00010,ko00053,ko00071,ko00250,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00250,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000,ko03000	Proline dehydrogenase
HELMLDPP_03160	6.02e-135	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_03163	8.29e-100	-	-	-	-	-	-	-	-
HELMLDPP_03164	8.41e-236	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_03165	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03166	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_03167	0.0	-	-	-	G	-	-	-	hydrolase, family 65, central catalytic
HELMLDPP_03168	8.93e-17	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HELMLDPP_03169	0.0	-	-	-	P	-	-	-	Right handed beta helix region
HELMLDPP_03170	0.0	betC_2	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_03171	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HELMLDPP_03172	0.0	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HELMLDPP_03173	0.0	-	3.2.1.52	GH20	G	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	ko00000,ko00001,ko00002,ko01000,ko03110	Glycosyl hydrolase family 20, catalytic domain protein
HELMLDPP_03174	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
HELMLDPP_03176	3.48e-62	-	-	-	-	-	-	-	-
HELMLDPP_03177	3.83e-47	-	-	-	S	-	-	-	Transglycosylase associated protein
HELMLDPP_03178	0.0	-	-	-	M	-	-	-	Outer membrane efflux protein
HELMLDPP_03179	0.0	-	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_03180	1.12e-266	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Biotin-lipoyl like
HELMLDPP_03181	1.63e-95	-	-	-	-	-	-	-	-
HELMLDPP_03182	2.71e-280	pepQ	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	xaa-pro dipeptidase K01271
HELMLDPP_03183	0.0	-	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Psort location Cytoplasmic, score
HELMLDPP_03184	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HELMLDPP_03185	4.95e-93	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HELMLDPP_03186	4.58e-224	gap	1.2.1.12	-	C	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HELMLDPP_03187	3.25e-223	miaA2	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HELMLDPP_03188	3.16e-231	-	-	-	I	-	-	-	lipid kinase, YegS Rv2252 BmrU family
HELMLDPP_03189	4.46e-184	kdsA	2.5.1.55	-	H	ko:K01627	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the KdsA family
HELMLDPP_03190	7.55e-120	-	1.16.3.1	-	S	ko:K03594	ko00860,map00860	ko00000,ko00001,ko01000	Ferritin-like domain
HELMLDPP_03191	6.24e-25	-	-	-	-	-	-	-	-
HELMLDPP_03192	1.55e-159	-	-	-	K	ko:K21556	-	ko00000,ko03000	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
HELMLDPP_03193	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
HELMLDPP_03194	0.0	-	-	-	-	-	-	-	-
HELMLDPP_03195	0.0	-	-	-	MU	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03196	9.71e-228	-	-	-	M	ko:K01993	-	ko00000	Biotin-lipoyl like
HELMLDPP_03197	1.19e-276	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03198	9.81e-279	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03199	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HELMLDPP_03202	7.69e-150	-	-	-	D	-	-	-	Domain of unknown function
HELMLDPP_03203	0.0	-	-	-	S	-	-	-	PD-(D/E)XK nuclease superfamily
HELMLDPP_03204	2.74e-243	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_03205	4.18e-315	-	-	-	-	-	-	-	-
HELMLDPP_03206	0.0	-	-	-	S	-	-	-	Domain of unknonw function from B. Theta Gene description (DUF3874)
HELMLDPP_03208	2.86e-316	-	-	-	S	ko:K06921	-	ko00000	ATPase (AAA superfamily)
HELMLDPP_03209	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_03210	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03211	3.69e-278	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03212	6.15e-188	-	-	-	C	-	-	-	4Fe-4S binding domain
HELMLDPP_03213	7.06e-274	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HELMLDPP_03214	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Peptidase family M1 domain
HELMLDPP_03215	1.14e-258	-	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 18 family
HELMLDPP_03216	1.81e-224	-	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG COG0524 Sugar kinases, ribokinase family
HELMLDPP_03217	1.58e-138	kdsD	5.3.1.13	-	M	ko:K06041	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	sugar phosphate isomerase involved in capsule formation
HELMLDPP_03218	3.16e-125	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HELMLDPP_03219	6.96e-296	-	-	-	S	-	-	-	Belongs to the peptidase M16 family
HELMLDPP_03220	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
HELMLDPP_03221	0.0	-	-	-	T	-	-	-	Two component regulator propeller
HELMLDPP_03222	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_03223	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_03224	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03225	5.16e-292	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HELMLDPP_03226	5.02e-188	uxuB	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HELMLDPP_03227	2.73e-166	-	-	-	C	-	-	-	WbqC-like protein
HELMLDPP_03228	2.49e-213	lepB_1	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HELMLDPP_03229	0.0	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	signal peptidase i
HELMLDPP_03230	1.98e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the DapB family
HELMLDPP_03231	6.32e-315	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03232	6.34e-147	-	-	-	-	-	-	-	-
HELMLDPP_03233	5.4e-177	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HELMLDPP_03234	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HELMLDPP_03235	8.89e-269	fucO	1.1.1.77	-	C	ko:K00048	ko00630,ko00640,ko01120,map00630,map00640,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03236	1.06e-153	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HELMLDPP_03237	0.0	-	-	-	L	ko:K06400	-	ko00000	Recombinase
HELMLDPP_03238	3.43e-236	-	-	-	-	-	-	-	-
HELMLDPP_03239	2.44e-207	-	-	-	-	-	-	-	-
HELMLDPP_03240	3.45e-74	-	-	-	-	-	-	-	-
HELMLDPP_03241	1.66e-101	-	-	-	-	-	-	-	-
HELMLDPP_03242	2.94e-34	-	-	-	-	-	-	-	-
HELMLDPP_03244	7.05e-185	-	-	-	S	-	-	-	Winged helix-turn-helix DNA-binding
HELMLDPP_03245	6.27e-248	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03246	8.45e-15	-	-	-	-	-	-	-	-
HELMLDPP_03247	2.01e-134	-	-	-	L	-	-	-	Phage integrase family
HELMLDPP_03248	1.04e-153	-	-	-	-	-	-	-	-
HELMLDPP_03249	2.07e-194	-	-	-	S	-	-	-	Domain of unknown function (DUF4595) with porin-like fold
HELMLDPP_03250	3.48e-142	-	-	-	S	-	-	-	P-loop ATPase and inactivated derivatives
HELMLDPP_03251	2.48e-226	dus	-	-	H	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HELMLDPP_03252	2.64e-94	-	-	-	S	ko:K07107	-	ko00000,ko01000	acyl-CoA thioester hydrolase, YbgC YbaW family
HELMLDPP_03253	4.62e-253	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HELMLDPP_03254	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	F5 8 type C domain protein
HELMLDPP_03255	0.000602	-	-	-	-	-	-	-	-
HELMLDPP_03256	8.13e-301	-	-	-	M	-	-	-	COG NOG24980 non supervised orthologous group
HELMLDPP_03257	6.95e-238	-	-	-	S	-	-	-	COG NOG26135 non supervised orthologous group
HELMLDPP_03258	8.09e-235	-	-	-	S	-	-	-	Fimbrillin-like
HELMLDPP_03260	3.21e-81	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HELMLDPP_03261	9.71e-28	-	-	-	H	-	-	-	COG NOG08812 non supervised orthologous group
HELMLDPP_03262	3.61e-207	-	-	-	K	-	-	-	Transcriptional regulator, AraC family
HELMLDPP_03263	7.48e-185	frdB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0479 Succinate dehydrogenase fumarate reductase Fe-S protein subunit
HELMLDPP_03264	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit
HELMLDPP_03265	4.86e-165	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	Succinate dehydrogenase cytochrome B subunit, b558 family
HELMLDPP_03266	7.76e-145	-	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	PAP2 superfamily
HELMLDPP_03267	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HELMLDPP_03268	2.11e-105	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HELMLDPP_03269	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0187 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) B subunit
HELMLDPP_03270	2.69e-276	yghO	-	-	K	-	-	-	COG NOG07967 non supervised orthologous group
HELMLDPP_03271	1.3e-215	yrbG	-	-	P	ko:K07301	-	ko00000,ko02000	K -dependent Na Ca exchanger
HELMLDPP_03272	6.23e-245	-	3.1.3.2	-	S	ko:K14379	ko00740,ko01100,ko04142,ko04380,ko05323,map00740,map01100,map04142,map04380,map05323	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HELMLDPP_03273	0.0	-	-	-	M	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03274	9.07e-197	-	-	-	KT	-	-	-	COG COG3279 Response regulator of the LytR AlgR family
HELMLDPP_03275	5.67e-178	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03276	1.58e-122	-	-	-	-	-	-	-	-
HELMLDPP_03277	0.0	-	-	-	N	-	-	-	nuclear chromosome segregation
HELMLDPP_03278	1.42e-112	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_03279	3.01e-119	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
HELMLDPP_03280	3.71e-193	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03281	5.07e-298	rhlE	3.6.4.13	-	JKL	ko:K11927	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Belongs to the DEAD box helicase family
HELMLDPP_03282	0.0	-	-	-	S	-	-	-	PQQ enzyme repeat protein
HELMLDPP_03283	1.76e-234	-	-	-	L	-	-	-	Endonuclease/Exonuclease/phosphatase family
HELMLDPP_03284	1e-221	cysK	2.5.1.47	-	E	ko:K01738,ko:K12339	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HELMLDPP_03285	2.44e-269	trmU	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HELMLDPP_03286	4.86e-145	narL	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HELMLDPP_03288	1.03e-266	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HELMLDPP_03289	4.15e-188	-	-	-	-	-	-	-	-
HELMLDPP_03290	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ)
HELMLDPP_03291	0.0	-	-	-	H	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03292	3.1e-117	-	-	-	CO	-	-	-	Redoxin family
HELMLDPP_03293	2.06e-184	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HELMLDPP_03294	1.72e-285	-	-	-	M	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03295	4.53e-263	-	-	-	S	-	-	-	Sulfotransferase family
HELMLDPP_03296	0.0	cysN	2.7.1.25, 2.7.7.4	-	H	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily
HELMLDPP_03297	2.38e-223	cysD	2.7.7.4	-	H	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase
HELMLDPP_03298	2.24e-140	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HELMLDPP_03299	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03300	1.15e-197	cysQ	3.1.3.7	-	P	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	ko00000,ko00001,ko01000,ko03016	3'(2'),5'-bisphosphate nucleotidase
HELMLDPP_03301	5.26e-302	-	-	-	M	-	-	-	COG NOG26016 non supervised orthologous group
HELMLDPP_03302	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HELMLDPP_03303	1.86e-63	-	-	-	S	-	-	-	COG NOG23401 non supervised orthologous group
HELMLDPP_03304	0.0	lptD	-	-	M	-	-	-	COG NOG06415 non supervised orthologous group
HELMLDPP_03305	0.0	surA	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	peptidylprolyl isomerase
HELMLDPP_03306	3.91e-211	-	-	-	O	-	-	-	COG NOG23400 non supervised orthologous group
HELMLDPP_03307	0.0	-	5.2.1.8	-	M	ko:K03771	-	ko00000,ko01000,ko03110	COG COG0760 Parvulin-like peptidyl-prolyl isomerase
HELMLDPP_03308	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HELMLDPP_03310	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HELMLDPP_03311	4.52e-301	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HELMLDPP_03312	1.34e-155	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HELMLDPP_03313	6.37e-312	tig	-	-	O	ko:K03545	-	ko00000	peptidyl-prolyl cis-trans isomerase (trigger factor)
HELMLDPP_03314	2.07e-50	-	-	-	S	-	-	-	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HELMLDPP_03315	2.81e-191	lptB	-	-	S	ko:K06861	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Psort location Cytoplasmic, score 9.12
HELMLDPP_03316	6.53e-172	mlaE	-	-	Q	ko:K02066	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03317	3.69e-182	metN	-	-	Q	ko:K02065	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_03318	1.83e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HELMLDPP_03319	2.25e-207	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HELMLDPP_03320	8.58e-249	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HELMLDPP_03321	3.5e-40	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HELMLDPP_03322	9.71e-127	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03323	1.83e-277	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03324	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03325	1.38e-136	-	-	-	-	-	-	-	-
HELMLDPP_03326	2.58e-41	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03327	0.0	nrdA	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HELMLDPP_03328	1.25e-264	nrdB	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HELMLDPP_03329	4.32e-233	metF	1.5.1.20	-	E	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Methylenetetrahydrofolate reductase
HELMLDPP_03330	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_03331	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_03332	1.16e-285	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HELMLDPP_03333	0.0	dxs2	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HELMLDPP_03334	2.89e-220	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HELMLDPP_03335	1.55e-223	-	-	-	K	-	-	-	transcriptional regulator (AraC family)
HELMLDPP_03336	4.14e-121	-	-	-	C	-	-	-	Flavodoxin
HELMLDPP_03337	1.38e-132	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein
HELMLDPP_03338	0.0	cobJ	5.4.99.60, 5.4.99.61	-	H	ko:K06042	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG1010 Precorrin-3B methylase
HELMLDPP_03339	9.19e-287	cbiE	2.1.1.132	-	H	ko:K00595	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE
HELMLDPP_03340	0.0	cobM	2.1.1.133, 2.1.1.271	-	H	ko:K05936	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG2875 Precorrin-4 methylase
HELMLDPP_03341	0.0	cbiD	2.1.1.195	-	H	ko:K02188	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HELMLDPP_03342	2.26e-242	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HELMLDPP_03343	1.73e-228	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HELMLDPP_03344	5.26e-281	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HELMLDPP_03345	1.14e-170	-	2.1.1.130, 2.1.1.151	-	H	ko:K03394	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko01000	COG2243 Precorrin-2 methylase
HELMLDPP_03346	2.95e-92	-	-	-	-	-	-	-	-
HELMLDPP_03347	0.0	uxaB	1.1.1.17, 1.1.1.58	-	C	ko:K00009,ko:K00041	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the mannitol dehydrogenase family. UxaB subfamily
HELMLDPP_03348	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HELMLDPP_03349	4.46e-297	-	-	-	CO	-	-	-	COG NOG23392 non supervised orthologous group
HELMLDPP_03350	1.96e-226	-	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HELMLDPP_03351	2.83e-197	vicX	-	-	S	-	-	-	Metallo-beta-lactamase domain protein
HELMLDPP_03355	1.15e-43	-	-	-	-	-	-	-	-
HELMLDPP_03356	1.21e-130	-	-	-	S	-	-	-	COG NOG27239 non supervised orthologous group
HELMLDPP_03357	7.72e-53	-	-	-	-	-	-	-	-
HELMLDPP_03358	0.0	-	-	-	M	-	-	-	Outer membrane protein, OMP85 family
HELMLDPP_03359	2.58e-176	aviRb	-	-	J	ko:K03437	-	ko00000,ko03016	RNA methyltransferase, TrmH
HELMLDPP_03360	6.4e-75	-	-	-	-	-	-	-	-
HELMLDPP_03361	6.13e-232	-	-	-	S	-	-	-	COG NOG25370 non supervised orthologous group
HELMLDPP_03362	2.15e-151	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HELMLDPP_03363	5.93e-80	yocK	-	-	T	-	-	-	RNA polymerase-binding protein DksA
HELMLDPP_03364	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HELMLDPP_03365	2.15e-197	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_03366	3.96e-186	loiP	-	-	M	ko:K07387	-	ko00000,ko01000,ko01002	COG0501 Zn-dependent protease with chaperone function
HELMLDPP_03367	1.77e-165	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
HELMLDPP_03368	1.04e-247	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Kinase, PfkB family
HELMLDPP_03369	1.16e-264	-	-	-	K	ko:K02529	-	ko00000,ko03000	Psort location Cytoplasmic, score
HELMLDPP_03370	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03371	1.19e-296	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HELMLDPP_03372	2.06e-198	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
HELMLDPP_03373	3.47e-54	-	-	-	S	-	-	-	COG NOG18433 non supervised orthologous group
HELMLDPP_03374	6.64e-139	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03375	0.0	-	-	-	P	ko:K03305	-	ko00000	amino acid peptide transporter
HELMLDPP_03376	1.96e-113	ybaK	-	-	H	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HELMLDPP_03377	0.0	uvrA2	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HELMLDPP_03378	0.0	lysM	-	-	M	-	-	-	LysM domain
HELMLDPP_03379	6.39e-165	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_03380	6.95e-95	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03381	9.69e-72	rpoZ	-	-	S	-	-	-	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HELMLDPP_03382	6.38e-195	yfiO	-	-	S	ko:K05807	-	ko00000,ko02000	outer membrane assembly lipoprotein YfiO
HELMLDPP_03383	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HELMLDPP_03384	5.56e-246	-	-	-	P	-	-	-	phosphate-selective porin
HELMLDPP_03385	1.7e-133	yigZ	-	-	S	-	-	-	YigZ family
HELMLDPP_03386	7.91e-120	-	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
HELMLDPP_03387	0.0	-	-	-	M	ko:K07001	-	ko00000	Phospholipase, patatin family
HELMLDPP_03388	5.58e-292	uxuA	4.2.1.8	-	H	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HELMLDPP_03389	0.0	pulA	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HELMLDPP_03390	8.94e-135	ruvC	3.1.22.4	-	L	ko:K01159	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HELMLDPP_03391	2.21e-70	-	-	-	S	-	-	-	COG NOG30624 non supervised orthologous group
HELMLDPP_03393	6.19e-18	-	-	-	-	-	-	-	-
HELMLDPP_03395	3.58e-185	-	-	-	S	-	-	-	Domain of unknown function (DUF4906)
HELMLDPP_03396	5.28e-62	-	-	-	-	-	-	-	-
HELMLDPP_03397	3.3e-29	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HELMLDPP_03399	6.47e-62	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_03401	8.73e-280	-	-	-	L	-	-	-	Arm DNA-binding domain
HELMLDPP_03403	6.58e-88	-	-	-	-	-	-	-	-
HELMLDPP_03404	2.73e-38	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HELMLDPP_03405	1.34e-64	-	-	-	S	-	-	-	Glycosyl hydrolase 108
HELMLDPP_03406	7.99e-76	-	-	-	-	-	-	-	-
HELMLDPP_03408	4.84e-89	-	-	-	K	-	-	-	BRO family, N-terminal domain
HELMLDPP_03410	3.38e-35	-	-	-	-	-	-	-	-
HELMLDPP_03411	3.68e-144	-	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HELMLDPP_03412	5.57e-247	yjmD_1	-	-	E	-	-	-	Psort location Cytoplasmic, score 9.97
HELMLDPP_03413	9.23e-307	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
HELMLDPP_03414	6.36e-228	-	-	-	S	ko:K07045	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03415	6.61e-229	fdh	1.1.1.122	-	C	ko:K00064	ko00051,ko00053,ko01100,ko01110,ko01120,map00051,map00053,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Oxidoreductase, aldo keto reductase family protein
HELMLDPP_03416	2.6e-198	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_03417	0.0	-	3.2.1.51	GH29	G	ko:K01206	ko00511,map00511	ko00000,ko00001,ko01000,ko04147	Alpha-L-fucosidase
HELMLDPP_03418	0.0	-	-	-	H	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03419	0.0	-	-	-	F	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_03420	1.63e-91	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03422	2.39e-254	-	-	-	M	-	-	-	peptidase S41
HELMLDPP_03423	1.11e-201	-	-	-	S	-	-	-	COG NOG19130 non supervised orthologous group
HELMLDPP_03424	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	COG0188 Type IIA topoisomerase (DNA gyrase topo II topoisomerase IV) A subunit
HELMLDPP_03425	0.0	glyQS	6.1.1.14	-	J	ko:K01880	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of glycine to tRNA(Gly)
HELMLDPP_03426	6.43e-153	mip	5.2.1.8	-	M	ko:K03773	-	ko00000,ko01000,ko03110	FKBP-type peptidyl-prolyl cis-trans isomerase
HELMLDPP_03427	1.93e-241	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HELMLDPP_03428	0.0	ybaL_1	-	-	PT	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03429	1.39e-170	hypB	-	-	H	ko:K22132	-	ko00000,ko03016	involved in molybdopterin and thiamine biosynthesis family 1
HELMLDPP_03430	1.44e-148	lolD	-	-	V	ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner
HELMLDPP_03431	5.92e-235	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HELMLDPP_03432	0.0	yqhD	-	-	C	ko:K08325	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03433	5.5e-200	yitL	-	-	S	ko:K00243	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03434	2.54e-216	-	-	-	S	-	-	-	COG NOG36047 non supervised orthologous group
HELMLDPP_03436	1.17e-305	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	Psort location OuterMembrane, score 10.00
HELMLDPP_03437	6.19e-243	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_03438	1.9e-296	macB_3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HELMLDPP_03439	5.91e-298	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HELMLDPP_03440	8.68e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_03441	1.1e-229	glk	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 9.26
HELMLDPP_03442	7.42e-89	-	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03443	1.83e-06	-	-	-	-	-	-	-	-
HELMLDPP_03445	3.87e-237	iaaA	3.4.19.5	-	E	ko:K13051	-	ko00000,ko01000,ko01002	Asparaginase
HELMLDPP_03446	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
HELMLDPP_03447	0.0	-	-	-	M	-	-	-	Right handed beta helix region
HELMLDPP_03448	2.97e-208	-	-	-	S	-	-	-	Pkd domain containing protein
HELMLDPP_03449	1.2e-176	-	-	-	G	-	-	-	Domain of unknown function (DUF4450)
HELMLDPP_03450	2.03e-204	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_03452	8.53e-95	-	-	-	-	-	-	-	-
HELMLDPP_03453	1.16e-69	-	-	-	L	ko:K07484	-	ko00000	COG COG3436 Transposase and inactivated derivatives
HELMLDPP_03454	3.71e-140	-	-	-	L	-	-	-	Transposase IS66 family
HELMLDPP_03455	1.98e-199	-	-	-	L	-	-	-	Transposase IS66 family
HELMLDPP_03456	1.22e-19	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
HELMLDPP_03457	2.95e-98	-	-	-	S	-	-	-	Domain of unknown function (DUF4373)
HELMLDPP_03459	5.57e-67	-	-	-	L	-	-	-	PFAM Integrase catalytic
HELMLDPP_03460	1.57e-190	spoU	-	-	H	ko:K03437	-	ko00000,ko03016	RNA methyltransferase TrmH family
HELMLDPP_03461	3.04e-260	yjmD_2	-	-	E	ko:K18369	ko00640,map00640	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03462	1.66e-97	hsp20	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HELMLDPP_03463	1.62e-83	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_03464	1.6e-215	-	-	-	IQ	-	-	-	Oxidoreductase, short chain dehydrogenase reductase family protein
HELMLDPP_03465	1.34e-234	gloA	4.4.1.5	-	E	ko:K01759,ko:K03827	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03466	1.4e-105	nodN	-	-	I	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03467	1.44e-42	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03468	3.96e-46	ogt	2.1.1.63	-	L	ko:K00567,ko:K07443	-	ko00000,ko01000,ko03400	6-O-methylguanine DNA methyltransferase, DNA binding domain
HELMLDPP_03469	1.06e-115	-	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HELMLDPP_03470	3.04e-128	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HELMLDPP_03471	1.5e-44	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03472	0.0	-	-	-	KL	-	-	-	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HELMLDPP_03473	0.0	rluA	5.4.99.28, 5.4.99.29	-	J	ko:K06177	-	ko00000,ko01000,ko03009,ko03016	Pseudouridine synthase, RluA family
HELMLDPP_03474	0.0	mepA_7	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03475	0.0	trkH	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03476	1.22e-269	-	-	-	M	ko:K03585	ko01501,ko01503,map01501,map01503	ko00000,ko00001,ko00002,ko01504,ko02000,ko03036	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_03477	0.0	-	-	-	V	-	-	-	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HELMLDPP_03478	0.0	-	-	-	M	ko:K18139,ko:K18300	ko01501,ko02024,map01501,map02024	ko00000,ko00001,ko00002,ko01504,ko02000	Efflux transporter, outer membrane factor lipoprotein, NodT family
HELMLDPP_03479	1.9e-300	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_03480	1.67e-293	-	-	-	S	ko:K07133	-	ko00000	ATPase (AAA superfamily)
HELMLDPP_03481	0.0	nifJ	1.2.7.1	-	C	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HELMLDPP_03483	0.0	-	-	-	P	-	-	-	Type I phosphodiesterase / nucleotide pyrophosphatase
HELMLDPP_03485	6.92e-189	-	-	-	S	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_03487	1.88e-291	-	-	-	-	-	-	-	-
HELMLDPP_03488	0.0	opuAC	-	-	S	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	dextransucrase activity
HELMLDPP_03489	1.27e-222	-	-	-	-	-	-	-	-
HELMLDPP_03490	1.27e-220	-	-	-	-	-	-	-	-
HELMLDPP_03491	1.81e-109	-	-	-	-	-	-	-	-
HELMLDPP_03493	5.57e-110	-	-	-	-	-	-	-	-
HELMLDPP_03495	5.46e-184	-	-	-	T	ko:K02477	-	ko00000,ko02022	COG3279 Response regulator of the LytR AlgR family
HELMLDPP_03496	0.0	-	-	-	T	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_03497	9.72e-226	lacX	-	-	G	-	-	-	COG COG2017 Galactose mutarotase and related enzymes
HELMLDPP_03498	3.6e-226	-	-	-	EG	ko:K08978	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03499	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II
HELMLDPP_03500	0.0	-	-	-	M	-	-	-	Dipeptidase
HELMLDPP_03501	0.0	-	-	-	M	-	-	-	Peptidase, M23 family
HELMLDPP_03502	1.3e-264	ald	1.4.1.1	-	C	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HELMLDPP_03503	7.98e-188	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HELMLDPP_03504	8.52e-37	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HELMLDPP_03506	2.53e-113	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_03507	4.26e-103	-	-	-	-	-	-	-	-
HELMLDPP_03508	2.12e-292	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03509	3.5e-224	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03510	1.71e-209	cysL	-	-	K	-	-	-	LysR substrate binding domain protein
HELMLDPP_03511	4.75e-132	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03512	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HELMLDPP_03513	6.26e-96	-	-	-	S	-	-	-	COG NOG14473 non supervised orthologous group
HELMLDPP_03514	1.03e-133	coaE	2.7.1.24	-	H	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HELMLDPP_03515	1.2e-240	-	-	-	S	-	-	-	COG NOG14472 non supervised orthologous group
HELMLDPP_03516	8.58e-65	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	COG1862 Preprotein translocase subunit YajC
HELMLDPP_03517	3.47e-214	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HELMLDPP_03518	4.68e-82	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03519	3.07e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HELMLDPP_03520	4.44e-134	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HELMLDPP_03521	9e-94	hslR	-	-	J	ko:K04762	-	ko00000,ko03110	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HELMLDPP_03522	6.87e-102	-	-	-	FG	-	-	-	Histidine triad domain protein
HELMLDPP_03523	0.0	nhaA	-	-	P	ko:K03455	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03524	7e-268	gcvT	2.1.2.10	-	H	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HELMLDPP_03525	2.93e-301	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HELMLDPP_03526	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	glutamine phosphoribosylpyrophosphate amidotransferase
HELMLDPP_03527	1.24e-82	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HELMLDPP_03528	1.06e-184	-	-	-	S	-	-	-	NigD-like N-terminal OB domain
HELMLDPP_03530	7.45e-167	-	-	-	S	ko:K06950	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03531	6.87e-131	-	-	-	S	-	-	-	COG NOG28927 non supervised orthologous group
HELMLDPP_03532	0.0	copA	3.6.3.4, 3.6.3.54	-	P	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03533	1.78e-203	-	-	-	S	-	-	-	Domain of unknown function (DUF4163)
HELMLDPP_03534	2.16e-149	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HELMLDPP_03535	2.16e-160	-	-	-	P	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_03536	0.0	gcvP	1.4.4.2	-	E	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HELMLDPP_03537	0.0	-	-	-	E	-	-	-	Peptidase, S9A B C family, catalytic domain protein
HELMLDPP_03538	4.63e-48	-	-	-	-	-	-	-	-
HELMLDPP_03539	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Formyltetrahydrofolate synthetase
HELMLDPP_03540	8.2e-289	-	-	-	C	ko:K19955	-	ko00000,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03541	7.87e-264	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03542	7.32e-136	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03543	0.0	-	-	-	D	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03544	7.44e-234	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03545	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	COG COG3973 Superfamily I DNA and RNA helicases
HELMLDPP_03546	5.11e-208	-	-	-	-	-	-	-	-
HELMLDPP_03547	9.2e-317	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03548	1.34e-188	phnX	3.11.1.1	-	S	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HELMLDPP_03549	3.91e-270	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HELMLDPP_03550	4.56e-291	-	-	-	P	ko:K07221	-	ko00000,ko02000	Phosphate-selective porin O and P
HELMLDPP_03551	9.73e-308	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03552	0.0	ravA_1	-	-	S	ko:K03924	-	ko00000,ko01000	ATPase family associated with various cellular activities (AAA)
HELMLDPP_03553	9.07e-178	cypM_1	-	-	H	-	-	-	Methyltransferase domain protein
HELMLDPP_03554	3.42e-200	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HELMLDPP_03555	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HELMLDPP_03556	3.11e-124	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HELMLDPP_03557	6.14e-83	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HELMLDPP_03558	8.66e-40	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HELMLDPP_03559	1.34e-257	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HELMLDPP_03560	8.76e-85	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03561	2.28e-53	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	ATP synthase, delta epsilon subunit, beta-sandwich domain protein
HELMLDPP_03562	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HELMLDPP_03563	0.0	-	-	-	S	-	-	-	Peptidase family M28
HELMLDPP_03564	1.41e-211	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	Ppx GppA phosphatase family
HELMLDPP_03565	0.0	ppk	2.7.4.1	-	H	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HELMLDPP_03566	1.98e-281	-	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03567	1.78e-200	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase superfamily domain
HELMLDPP_03568	9.67e-104	-	-	-	S	-	-	-	COG NOG14442 non supervised orthologous group
HELMLDPP_03569	1.64e-300	qseC	-	-	T	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03570	5.9e-160	-	-	-	K	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HELMLDPP_03571	1.06e-181	-	-	-	S	-	-	-	COG NOG29298 non supervised orthologous group
HELMLDPP_03572	0.0	-	-	-	P	-	-	-	COG COG3119 Arylsulfatase A and related enzymes
HELMLDPP_03573	1.26e-133	-	-	-	K	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
HELMLDPP_03574	0.0	hcp	1.7.99.1	-	C	ko:K05601	ko00910,map00910	ko00000,ko00001,ko01000	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O
HELMLDPP_03575	4.16e-178	ric	-	-	C	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
HELMLDPP_03576	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
HELMLDPP_03577	0.0	-	-	-	T	-	-	-	COG COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain
HELMLDPP_03579	1.37e-146	-	-	-	K	ko:K07735	-	ko00000,ko03000	Belongs to the UPF0301 (AlgH) family
HELMLDPP_03580	2.41e-129	speG	2.3.1.57	-	J	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	Acetyltransferase, gnat family
HELMLDPP_03581	5.86e-99	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03582	1.77e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HELMLDPP_03583	0.0	-	-	-	E	-	-	-	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HELMLDPP_03584	8.17e-141	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HELMLDPP_03585	0.0	-	-	-	L	-	-	-	helicase
HELMLDPP_03586	1.57e-15	-	-	-	-	-	-	-	-
HELMLDPP_03588	5.68e-156	-	-	-	L	-	-	-	VirE N-terminal domain protein
HELMLDPP_03589	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
HELMLDPP_03590	3.31e-35	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HELMLDPP_03591	1.42e-112	-	-	-	L	-	-	-	regulation of translation
HELMLDPP_03593	5.1e-128	-	-	-	V	-	-	-	Ami_2
HELMLDPP_03594	5.95e-60	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03595	2.74e-137	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03596	2.07e-203	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_03597	4.25e-50	-	-	-	-	-	-	-	-
HELMLDPP_03598	1.3e-146	-	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03599	1.05e-114	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_03601	2.73e-62	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HELMLDPP_03603	5.01e-80	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_03604	7.67e-07	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03605	4.01e-160	-	5.4.99.9	-	H	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HELMLDPP_03606	9.68e-198	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03607	2.97e-55	-	-	-	-	-	-	-	-
HELMLDPP_03609	3.87e-200	-	-	-	-	-	-	-	-
HELMLDPP_03611	2.75e-287	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03612	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_03613	2.84e-202	-	-	-	S	-	-	-	COG NOG25193 non supervised orthologous group
HELMLDPP_03614	5.93e-93	gloA	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03615	2.83e-195	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03616	6.45e-284	-	-	-	T	-	-	-	COG NOG06399 non supervised orthologous group
HELMLDPP_03617	3.87e-80	ridA	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	endoribonuclease L-PSP
HELMLDPP_03618	0.0	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HELMLDPP_03619	0.0	-	-	-	P	-	-	-	Right handed beta helix region
HELMLDPP_03620	0.0	-	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
HELMLDPP_03621	0.0	-	-	-	E	-	-	-	B12 binding domain
HELMLDPP_03622	0.0	-	-	-	S	ko:K03307	-	ko00000	Sodium:solute symporter family
HELMLDPP_03623	8.4e-166	-	-	-	E	-	-	-	Vitamin B12 dependent methionine synthase, activation domain protein
HELMLDPP_03624	7.85e-241	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
HELMLDPP_03625	0.0	-	-	-	G	-	-	-	Histidine acid phosphatase
HELMLDPP_03626	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_03627	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03628	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_03629	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03630	2.72e-141	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03631	1.31e-42	-	-	-	-	-	-	-	-
HELMLDPP_03632	9.34e-130	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_03633	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_03634	0.0	-	-	-	G	-	-	-	pectate lyase K01728
HELMLDPP_03635	6.36e-148	-	-	-	G	-	-	-	Protein of unknown function (DUF3826)
HELMLDPP_03636	0.0	-	-	-	G	-	-	-	pectate lyase K01728
HELMLDPP_03637	0.0	-	-	-	P	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_03638	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03639	6.52e-217	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HELMLDPP_03640	0.0	-	-	-	T	-	-	-	cheY-homologous receiver domain
HELMLDPP_03641	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_03643	0.0	yhgF	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain
HELMLDPP_03644	1.93e-203	nudC	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	COG COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding
HELMLDPP_03645	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03646	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
HELMLDPP_03647	1.57e-77	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HELMLDPP_03648	3.59e-203	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HELMLDPP_03649	2.63e-201	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Starch synthase, catalytic domain
HELMLDPP_03650	0.0	-	-	-	S	-	-	-	Domain of unknown function (DUF4270)
HELMLDPP_03651	6.68e-90	-	-	-	L	-	-	-	COG NOG19098 non supervised orthologous group
HELMLDPP_03652	1.99e-260	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HELMLDPP_03653	1.15e-187	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III epsilon subunit and related 3'-5'
HELMLDPP_03654	1.52e-283	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HELMLDPP_03655	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HELMLDPP_03656	6.61e-181	trmH	2.1.1.185	-	J	ko:K03218,ko:K03437	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HELMLDPP_03657	0.0	-	-	-	O	-	-	-	COG COG0457 FOG TPR repeat
HELMLDPP_03658	9.58e-317	tilS	6.3.4.19	-	D	ko:K04075	-	ko00000,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HELMLDPP_03659	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HELMLDPP_03661	1.67e-157	pdxH	1.4.3.5	-	H	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)
HELMLDPP_03662	1.27e-276	wbsE	-	-	M	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_03665	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 9.97
HELMLDPP_03666	2.82e-180	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HELMLDPP_03667	3.83e-177	-	-	-	-	-	-	-	-
HELMLDPP_03668	2.44e-135	lutC	-	-	S	ko:K00782	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03669	0.0	-	-	-	C	ko:K18929	-	ko00000	electron transport protein YkgF
HELMLDPP_03670	1.15e-181	-	-	-	C	ko:K18928	-	ko00000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03671	1.03e-140	-	-	-	K	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HELMLDPP_03672	1.15e-169	-	-	-	D	ko:K07322	-	ko00000	Hemerythrin HHE cation binding domain protein
HELMLDPP_03673	2.06e-107	-	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HELMLDPP_03674	3.39e-167	yehT_1	-	-	K	-	-	-	COG3279 Response regulator of the LytR AlgR family
HELMLDPP_03675	1.8e-249	cheA	-	-	T	-	-	-	two-component sensor histidine kinase
HELMLDPP_03676	1.29e-279	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	Efflux ABC transporter, permease protein
HELMLDPP_03677	2.9e-171	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HELMLDPP_03678	7.95e-247	-	-	-	M	ko:K02005	-	ko00000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HELMLDPP_03679	4.18e-299	-	-	-	MU	ko:K12340	ko01501,ko01503,ko02020,ko03070,ko04626,ko05133,map01501,map01503,map02020,map03070,map04626,map05133	ko00000,ko00001,ko00002,ko01504,ko02000,ko02044	type I secretion outer membrane protein, TolC family
HELMLDPP_03680	9.82e-45	-	-	-	S	-	-	-	COG NOG17489 non supervised orthologous group
HELMLDPP_03681	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1271 Cytochrome bd-type quinol oxidase, subunit 1
HELMLDPP_03682	1.61e-274	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase subunit 2
HELMLDPP_03683	3.86e-174	pgl	3.1.1.31	-	G	ko:K01057	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase
HELMLDPP_03684	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HELMLDPP_03685	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HELMLDPP_03686	1.7e-261	sstT	-	-	U	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HELMLDPP_03687	1.54e-67	-	-	-	L	-	-	-	Nucleotidyltransferase domain
HELMLDPP_03688	5.77e-93	-	-	-	S	-	-	-	HEPN domain
HELMLDPP_03689	1.05e-299	-	-	-	M	-	-	-	Phosphate-selective porin O and P
HELMLDPP_03690	4.4e-246	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the asparaginase 1 family
HELMLDPP_03691	9.98e-288	dcuB	-	-	S	ko:K07791,ko:K07792	ko02020,map02020	ko00000,ko00001,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03692	6.1e-228	fabK	1.3.1.9	-	C	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	related to 2-nitropropane dioxygenase
HELMLDPP_03693	0.0	-	-	-	E	ko:K03307	-	ko00000	alkaline phosphatase synthesis sensor protein phoR K07636
HELMLDPP_03694	2.89e-223	-	4.3.3.7	-	H	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HELMLDPP_03695	0.0	modF	-	-	P	ko:K05776	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC molybdenum transporter, ATP-binding subunit modF
HELMLDPP_03696	5.86e-201	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HELMLDPP_03697	2.54e-308	dapL	2.6.1.83	-	H	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate
HELMLDPP_03698	8.4e-177	-	-	-	S	-	-	-	Psort location OuterMembrane, score
HELMLDPP_03699	2.13e-76	glnB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Nitrogen regulatory protein P-II
HELMLDPP_03700	0.0	amt	-	-	P	ko:K03320	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03701	0.0	glnA	6.3.1.2	-	S	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamate--ammonia ligase, catalytic domain protein
HELMLDPP_03702	1.64e-156	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HELMLDPP_03703	1.02e-182	bioC	2.1.1.197, 3.1.1.85	-	H	ko:K02169,ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway
HELMLDPP_03704	1.02e-156	bioC	2.1.1.197, 3.1.1.85	-	S	ko:K02169,ko:K09789	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Protein of unknown function (DUF452)
HELMLDPP_03705	9.35e-275	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	COG COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
HELMLDPP_03706	0.0	bioA	2.6.1.62	-	H	ko:K00833	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a
HELMLDPP_03707	5.05e-233	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HELMLDPP_03709	0.0	amyA	3.2.1.1	GH57	G	ko:K07405	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 57 family
HELMLDPP_03710	0.0	gmhA	2.4.1.346	GT4	M	ko:K13668	-	ko00000,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HELMLDPP_03711	0.0	-	-	-	G	-	-	-	glycogen debranching enzyme, archaeal type
HELMLDPP_03712	1.23e-160	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03713	0.0	-	-	-	O	-	-	-	unfolded protein binding
HELMLDPP_03714	5.1e-284	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03716	0.0	-	-	-	C	-	-	-	Di-haem oxidoreductase, putative peroxidase
HELMLDPP_03717	0.0	ccmC	-	-	O	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03718	1.25e-282	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HELMLDPP_03719	4.31e-235	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03720	2.81e-74	-	-	-	K	ko:K10947	-	ko00000,ko03000	transcriptional regulator PadR family
HELMLDPP_03721	3.11e-121	paiA	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03722	1.24e-172	-	-	-	L	-	-	-	DNA alkylation repair enzyme
HELMLDPP_03723	3.51e-314	-	-	-	S	-	-	-	Peptide-N-glycosidase F, N terminal
HELMLDPP_03724	0.0	-	-	-	H	-	-	-	COG NOG06391 non supervised orthologous group
HELMLDPP_03725	0.0	relA	2.7.6.5, 3.1.7.2	-	KT	ko:K00951,ko:K01139	ko00230,map00230	ko00000,ko00001,ko01000,ko03009	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HELMLDPP_03726	1.15e-75	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Psort location CytoplasmicMembrane, score
HELMLDPP_03727	1.58e-96	-	-	-	S	-	-	-	Protein of unknown function (DUF1573)
HELMLDPP_03728	1.79e-205	-	-	-	S	-	-	-	Ser Thr phosphatase family protein
HELMLDPP_03729	6.67e-189	-	-	-	S	-	-	-	COG NOG27188 non supervised orthologous group
HELMLDPP_03730	0.0	-	-	-	S	-	-	-	oligopeptide transporter, OPT family
HELMLDPP_03731	6.23e-208	-	-	-	I	-	-	-	pectin acetylesterase
HELMLDPP_03732	8.64e-112	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
HELMLDPP_03734	2.11e-89	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HELMLDPP_03735	6.63e-201	-	-	-	S	-	-	-	PD-(D/E)XK nuclease family transposase
HELMLDPP_03736	0.0	-	-	-	S	-	-	-	amine dehydrogenase activity
HELMLDPP_03737	0.0	-	-	-	P	-	-	-	TonB-dependent receptor
HELMLDPP_03740	4.18e-154	-	-	-	L	-	-	-	VirE N-terminal domain protein
HELMLDPP_03741	0.0	-	-	-	L	-	-	-	COG NOG25561 non supervised orthologous group
HELMLDPP_03742	2.92e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HELMLDPP_03743	6.03e-109	-	-	-	L	-	-	-	DNA-binding protein
HELMLDPP_03744	2.12e-10	-	-	-	-	-	-	-	-
HELMLDPP_03745	2.09e-101	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03746	1.6e-69	-	-	-	-	-	-	-	-
HELMLDPP_03747	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03748	0.0	-	-	-	P	-	-	-	Carboxypeptidase regulatory-like domain
HELMLDPP_03749	0.0	-	-	-	S	ko:K15738	-	ko00000,ko02000	ATP-binding cassette protein, ChvD family
HELMLDPP_03750	1.24e-277	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HELMLDPP_03751	9.38e-190	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HELMLDPP_03752	2.72e-156	pgmB	-	-	S	-	-	-	HAD hydrolase, family IA, variant 3
HELMLDPP_03753	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03754	0.0	cvrA	-	-	P	ko:K11105	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03755	8.89e-288	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family
HELMLDPP_03756	4.6e-89	-	-	-	-	-	-	-	-
HELMLDPP_03757	4.16e-315	-	-	-	Q	-	-	-	Clostripain family
HELMLDPP_03758	1.87e-84	-	-	-	S	-	-	-	COG NOG31446 non supervised orthologous group
HELMLDPP_03759	1.8e-189	rpoD	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HELMLDPP_03760	0.0	htrA	-	-	O	-	-	-	Psort location Periplasmic, score
HELMLDPP_03761	3.45e-133	ykgB	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_03762	9.85e-199	-	-	-	K	-	-	-	COG COG2207 AraC-type DNA-binding domain-containing proteins
HELMLDPP_03763	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_03764	0.0	-	-	-	Q	-	-	-	cephalosporin-C deacetylase activity
HELMLDPP_03765	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_03766	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HELMLDPP_03767	0.0	hypBA2	-	-	G	-	-	-	BNR repeat-like domain
HELMLDPP_03768	0.0	eam	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	KamA family
HELMLDPP_03769	0.0	-	-	-	P	ko:K16089	-	ko00000,ko02000	COG4771 Outer membrane receptor for ferrienterochelin and colicins
HELMLDPP_03770	2.01e-68	-	-	-	-	-	-	-	-
HELMLDPP_03771	0.0	cpdB	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HELMLDPP_03772	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_03773	6.37e-197	dnaJ2	-	-	O	ko:K03686,ko:K05516	-	ko00000,ko03029,ko03036,ko03110	Psort location Cytoplasmic, score
HELMLDPP_03774	5.01e-62	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03775	2.39e-310	yihY	-	-	S	ko:K07058	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03776	4.22e-143	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	riboflavin synthase subunit alpha
HELMLDPP_03777	8.23e-132	-	-	-	K	-	-	-	Psort location Cytoplasmic, score
HELMLDPP_03778	0.0	-	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	Psort location Cytoplasmic, score 9.97
HELMLDPP_03779	0.0	ybdG_1	-	-	M	ko:K16053	-	ko00000,ko02000	Mechanosensitive ion channel
HELMLDPP_03780	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_03782	0.0	-	-	-	L	-	-	-	viral genome integration into host DNA
HELMLDPP_03785	1.37e-60	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_03786	8.13e-45	-	-	-	-	-	-	-	-
HELMLDPP_03788	4.54e-242	-	-	-	L	-	-	-	COG NOG08810 non supervised orthologous group
HELMLDPP_03789	7.16e-278	-	-	-	L	-	-	-	helicase activity
HELMLDPP_03790	0.000742	polC	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	VRR_NUC
HELMLDPP_03794	5.93e-122	-	-	-	-	-	-	-	-
HELMLDPP_03795	3.13e-169	-	-	-	-	-	-	-	-
HELMLDPP_03796	1.82e-131	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HELMLDPP_03797	4.46e-35	-	2.6.1.2, 2.6.1.66	-	K	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	sequence-specific DNA binding
HELMLDPP_03798	1.06e-29	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03799	1.01e-54	-	-	-	S	-	-	-	WYL_2, Sm-like SH3 beta-barrel fold
HELMLDPP_03805	1.6e-89	-	-	-	-	-	-	-	-
HELMLDPP_03807	4.49e-169	ydaH	-	-	H	ko:K12942	-	ko00000	Psort location CytoplasmicMembrane, score
HELMLDPP_03808	2.21e-168	-	-	-	T	-	-	-	Response regulator receiver domain
HELMLDPP_03809	0.0	-	-	-	T	-	-	-	ATPase histidine kinase DNA gyrase B HSP90 domain protein
HELMLDPP_03810	3.07e-28	-	-	-	S	-	-	-	COG NOG16623 non supervised orthologous group
HELMLDPP_03811	1.63e-188	-	-	-	DT	-	-	-	aminotransferase class I and II
HELMLDPP_03812	5.26e-88	-	-	-	S	-	-	-	Protein of unknown function (DUF3037)
HELMLDPP_03813	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HELMLDPP_03814	3.93e-308	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_03815	9.65e-120	-	-	-	S	-	-	-	Domain of unknown function (DUF4625)
HELMLDPP_03816	0.0	-	-	-	P	ko:K02014	-	ko00000,ko02000	COG COG1629 Outer membrane receptor proteins, mostly Fe transport
HELMLDPP_03818	3.04e-235	pitA	-	-	P	ko:K03306	-	ko00000	Phosphate transporter family
HELMLDPP_03819	1.06e-148	-	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HELMLDPP_03820	1.22e-145	-	-	-	S	ko:K03975	-	ko00000	Psort location CytoplasmicMembrane, score
HELMLDPP_03821	3.76e-23	-	-	-	-	-	-	-	-
HELMLDPP_03822	2.53e-109	lrp	-	-	K	ko:K03719,ko:K05800	-	ko00000,ko03000,ko03036	Transcriptional regulator, AsnC family
HELMLDPP_03823	1.62e-254	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HELMLDPP_03824	2.16e-283	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03825	1.5e-129	-	-	-	K	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03826	0.0	cap5D	-	-	GM	-	-	-	Polysaccharide biosynthesis protein
HELMLDPP_03827	2.14e-279	-	-	-	M	-	-	-	chlorophyll binding
HELMLDPP_03828	7.22e-303	-	-	-	M	-	-	-	COG2885 Outer membrane protein and related peptidoglycan-associated
HELMLDPP_03829	5.31e-289	epsN	-	-	E	-	-	-	Belongs to the DegT DnrJ EryC1 family
HELMLDPP_03830	1.01e-95	-	-	-	-	-	-	-	-
HELMLDPP_03832	1.09e-274	-	-	-	C	ko:K22227	-	ko00000	4Fe-4S single cluster domain
HELMLDPP_03833	1.82e-278	-	-	-	S	ko:K22227	-	ko00000	4Fe-4S single cluster domain
HELMLDPP_03834	1.81e-221	-	-	-	-	-	-	-	-
HELMLDPP_03835	2.46e-102	-	-	-	U	-	-	-	peptidase
HELMLDPP_03836	1.45e-60	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HELMLDPP_03837	4.43e-60	-	-	-	S	-	-	-	Coenzyme PQQ synthesis protein D (PqqD)
HELMLDPP_03838	4.42e-275	-	-	-	S	-	-	-	Uncharacterised nucleotidyltransferase
HELMLDPP_03839	0.0	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03840	6.33e-186	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HELMLDPP_03841	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
HELMLDPP_03842	5.62e-165	-	-	-	GM	-	-	-	COG4464 Capsular polysaccharide biosynthesis protein
HELMLDPP_03843	2.64e-222	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family protein
HELMLDPP_03844	1.84e-200	-	-	-	GM	ko:K09690	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
HELMLDPP_03845	0.0	rfbB	-	-	GM	ko:K09691	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
HELMLDPP_03846	2.45e-223	-	-	-	C	-	-	-	coenzyme F420-reducing hydrogenase beta subunit
HELMLDPP_03847	1.07e-216	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HELMLDPP_03848	9.7e-233	-	-	-	S	-	-	-	Glycosyl transferase family 2
HELMLDPP_03849	6.93e-268	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03851	2.1e-37	-	-	-	-	-	-	-	-
HELMLDPP_03852	1.86e-125	-	-	-	S	-	-	-	Glycosyltransferase WbsX
HELMLDPP_03853	1.53e-42	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_03854	1.17e-74	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03855	1.95e-30	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HELMLDPP_03856	7.67e-223	rfaG	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_03857	1.61e-252	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03858	0.0	-	-	-	-	-	-	-	-
HELMLDPP_03859	1.96e-316	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03860	1.64e-182	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	Glycosyltransferase sugar-binding region containing DXD motif
HELMLDPP_03861	8.59e-295	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03862	3.19e-228	-	-	-	M	-	-	-	Glycosyl transferase family 2
HELMLDPP_03863	1.44e-256	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_03864	2.33e-284	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HELMLDPP_03865	7.04e-249	-	-	-	S	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_03866	8.34e-280	-	-	-	S	-	-	-	EpsG family
HELMLDPP_03868	6.64e-184	-	-	-	S	-	-	-	DUF218 domain
HELMLDPP_03869	1.76e-278	-	-	-	M	-	-	-	Glycosyltransferase, group 1 family protein
HELMLDPP_03870	5.49e-135	neuD	-	-	S	ko:K19429	-	ko00000,ko01000	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family
HELMLDPP_03871	5.31e-149	pglC	-	-	M	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03873	2.24e-263	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HELMLDPP_03874	0.0	-	-	-	G	-	-	-	hydrolase, family 65, central catalytic
HELMLDPP_03875	0.0	-	3.1.1.53	-	G	ko:K05970	-	ko00000,ko01000	COG NOG04984 non supervised orthologous group
HELMLDPP_03876	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase family 2, sugar binding domain protein
HELMLDPP_03877	0.0	-	-	-	G	-	-	-	beta-galactosidase
HELMLDPP_03878	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HELMLDPP_03879	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_03880	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03882	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_03883	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_03884	0.0	-	-	-	P	ko:K07085	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03885	2.05e-108	-	-	-	-	-	-	-	-
HELMLDPP_03886	0.0	-	-	-	S	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
HELMLDPP_03887	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
HELMLDPP_03888	2.06e-46	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_03889	0.0	-	-	-	G	-	-	-	Glycosyl hydrolase, family 20, catalytic domain
HELMLDPP_03890	7.67e-223	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03891	1.49e-137	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_03892	7.68e-253	-	-	-	U	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3868)
HELMLDPP_03893	1.55e-140	-	-	-	M	-	-	-	Protein of unknown function (DUF3575)
HELMLDPP_03894	0.0	-	-	-	M	-	-	-	COG NOG23378 non supervised orthologous group
HELMLDPP_03895	0.0	-	-	-	S	-	-	-	Major fimbrial subunit protein type IV, Fimbrillin, C-terminal
HELMLDPP_03896	4.02e-237	-	-	-	S	-	-	-	Fimbrillin-A associated anchor proteins Mfa1 and Mfa2
HELMLDPP_03897	2.05e-229	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_03898	0.0	wcaJ_2	2.7.8.6	-	M	ko:K00996,ko:K03606	ko05111,map05111	ko00000,ko00001,ko01000,ko01005	Psort location CytoplasmicMembrane, score
HELMLDPP_03899	4.99e-180	-	-	-	M	ko:K01991	ko02026,map02026	ko00000,ko00001,ko02000	COG1596 Periplasmic protein involved in polysaccharide export
HELMLDPP_03900	0.0	-	-	-	DM	-	-	-	Chain length determinant protein
HELMLDPP_03901	1.31e-112	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03902	0.000518	-	-	-	-	-	-	-	-
HELMLDPP_03903	7.4e-93	-	-	-	L	-	-	-	Bacterial DNA-binding protein
HELMLDPP_03904	5.71e-48	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HELMLDPP_03905	0.0	-	-	-	L	-	-	-	Protein of unknown function (DUF3987)
HELMLDPP_03906	8.53e-115	-	-	-	K	-	-	-	Transcription termination antitermination factor NusG
HELMLDPP_03907	2.33e-45	-	-	-	S	-	-	-	Nucleotidyltransferase domain
HELMLDPP_03908	4.39e-46	-	-	-	-	-	-	-	-
HELMLDPP_03909	3.62e-117	-	-	-	S	-	-	-	Bacterial transferase hexapeptide repeat protein
HELMLDPP_03910	0.0	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03911	4.34e-153	-	-	-	S	-	-	-	maltose O-acetyltransferase activity
HELMLDPP_03912	4.97e-152	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03913	3.6e-240	-	-	-	S	-	-	-	Glycosyl transferases group 1
HELMLDPP_03914	0.0	-	-	-	-	-	-	-	-
HELMLDPP_03915	7.22e-237	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03916	1.99e-160	-	-	-	S	-	-	-	maltose O-acetyltransferase activity
HELMLDPP_03917	3.11e-273	-	-	-	M	-	-	-	Glycosyl transferases group 1
HELMLDPP_03918	1.44e-133	-	-	-	S	ko:K03818	-	ko00000,ko01000	Bacterial transferase hexapeptide (six repeats)
HELMLDPP_03919	1.7e-196	-	-	GT2	S	ko:K13002	-	ko00000,ko01000,ko01003,ko01005	Glycosyl transferase family 2
HELMLDPP_03920	2.82e-180	-	-	-	S	-	-	-	Exopolysaccharide biosynthesis protein YbjH
HELMLDPP_03921	1.96e-294	-	-	-	-	-	-	-	-
HELMLDPP_03922	2.67e-273	-	-	-	S	-	-	-	COG NOG33609 non supervised orthologous group
HELMLDPP_03923	4.04e-266	gmd	4.2.1.47	-	M	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HELMLDPP_03924	2.45e-272	fcl	1.1.1.271	-	GM	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction
HELMLDPP_03925	3.28e-259	manC	2.7.7.13	-	M	ko:K00971	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	ko00000,ko00001,ko00002,ko01000	mannose-1-phosphate guanylyltransferase
HELMLDPP_03926	2.58e-102	-	-	-	E	-	-	-	D,D-heptose 1,7-bisphosphate phosphatase
HELMLDPP_03927	0.0	-	-	-	G	-	-	-	Alpha-L-rhamnosidase
HELMLDPP_03928	0.0	-	-	-	S	-	-	-	Parallel beta-helix repeats
HELMLDPP_03929	0.0	-	-	-	S	ko:K09955	-	ko00000	protein conserved in bacteria
HELMLDPP_03930	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Alpha-L-rhamnosidase N-terminal domain protein
HELMLDPP_03931	0.0	-	-	-	G	-	-	-	Putative collagen-binding domain of a collagenase
HELMLDPP_03932	2.07e-306	-	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HELMLDPP_03933	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	COG NOG04001 non supervised orthologous group
HELMLDPP_03934	3.13e-311	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HELMLDPP_03935	0.0	-	-	-	L	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03937	7.74e-121	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03938	1.76e-232	arnC	-	-	M	-	-	-	involved in cell wall biogenesis
HELMLDPP_03939	1.9e-103	-	-	-	S	-	-	-	COG NOG30522 non supervised orthologous group
HELMLDPP_03940	4e-171	-	-	-	S	-	-	-	COG NOG28307 non supervised orthologous group
HELMLDPP_03941	2.86e-127	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HELMLDPP_03942	6.02e-246	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HELMLDPP_03943	2.13e-127	marC	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HELMLDPP_03944	4.47e-155	-	-	-	K	-	-	-	- catabolite gene activator and regulatory subunit of cAMP-dependent protein
HELMLDPP_03945	0.0	dcp	3.4.15.5, 3.4.24.70	-	E	ko:K01284,ko:K01414	-	ko00000,ko01000,ko01002	Psort location Cytoplasmic, score
HELMLDPP_03946	8.14e-45	-	-	-	S	-	-	-	Domain of unknown function (DUF4847)
HELMLDPP_03947	4.11e-100	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	deaminase
HELMLDPP_03948	0.0	ctp	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HELMLDPP_03949	5.02e-115	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_03950	5.19e-60	-	-	-	S	-	-	-	COG NOG38282 non supervised orthologous group
HELMLDPP_03951	1.79e-266	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HELMLDPP_03952	3.82e-156	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_03953	4.56e-120	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HELMLDPP_03956	1.27e-265	-	-	-	L	-	-	-	COG NOG27661 non supervised orthologous group
HELMLDPP_03957	2.73e-204	-	-	-	S	-	-	-	Bacteriophage abortive infection AbiH
HELMLDPP_03958	4.75e-220	-	-	-	-	-	-	-	-
HELMLDPP_03959	1.17e-20	-	-	-	-	-	-	-	-
HELMLDPP_03961	7.8e-90	-	-	-	-	-	-	-	-
HELMLDPP_03962	0.0	-	-	-	JKL	-	-	-	Belongs to the DEAD box helicase family
HELMLDPP_03964	1.5e-127	-	-	-	-	-	-	-	-
HELMLDPP_03965	5.15e-247	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03966	6.97e-14	-	-	-	-	-	-	-	-
HELMLDPP_03967	1.72e-136	-	-	-	L	-	-	-	Phage integrase family
HELMLDPP_03968	3.49e-123	-	-	-	-	-	-	-	-
HELMLDPP_03969	1.91e-47	-	-	-	-	-	-	-	-
HELMLDPP_03972	1.94e-42	-	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	Trypsin-like peptidase domain
HELMLDPP_03973	8.34e-195	-	3.4.16.4	-	M	ko:K03587	ko00550,ko01501,map00550,map01501	ko00000,ko00001,ko01000,ko01011,ko03036	COG COG0768 Cell division protein FtsI penicillin-binding protein 2
HELMLDPP_03974	3.2e-157	-	-	-	-	-	-	-	-
HELMLDPP_03975	6.99e-11	-	-	-	-	-	-	-	-
HELMLDPP_03979	3.86e-174	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
HELMLDPP_03980	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat
HELMLDPP_03981	3.54e-299	-	-	-	S	-	-	-	Domain of unknown function (DUF4934)
HELMLDPP_03982	1.02e-187	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Psort location Cytoplasmic, score 9.97
HELMLDPP_03983	3.38e-74	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase SecG subunit
HELMLDPP_03984	2.02e-160	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03985	6.13e-117	lptE	-	-	S	-	-	-	COG NOG14471 non supervised orthologous group
HELMLDPP_03986	6.62e-296	fhlA	-	-	K	-	-	-	Sigma-54 interaction domain protein
HELMLDPP_03987	0.0	ino1	5.5.1.4	-	I	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	ko00000,ko00001,ko01000	Inositol-3-phosphate synthase
HELMLDPP_03988	2.11e-219	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03989	6.98e-285	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	L-fucose H symporter permease
HELMLDPP_03990	4.32e-174	-	3.1.3.102, 3.1.3.104	-	S	ko:K07025,ko:K20862	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	HAD-hyrolase-like
HELMLDPP_03991	6.17e-237	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_03992	1.64e-241	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_03993	2.45e-211	-	-	-	HJ	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_03994	9.39e-167	-	-	-	JM	-	-	-	Nucleotidyl transferase
HELMLDPP_03995	8.16e-265	pdxA	1.1.1.262	-	C	ko:K00097	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the PdxA family
HELMLDPP_03996	4.47e-256	-	-	-	L	-	-	-	COG NOG11654 non supervised orthologous group
HELMLDPP_03997	2.78e-252	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HELMLDPP_03998	0.0	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HELMLDPP_03999	0.0	lytB	-	-	D	ko:K06381	-	ko00000	SpoIID LytB domain protein
HELMLDPP_04000	0.0	ampG	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04002	1.04e-122	-	-	-	S	-	-	-	COG NOG27363 non supervised orthologous group
HELMLDPP_04003	2.99e-122	-	-	-	S	-	-	-	Domain of unknown function (DUF4251)
HELMLDPP_04004	4.49e-143	-	-	-	S	-	-	-	Domain of unknown function (DUF4136)
HELMLDPP_04005	4.37e-160	-	-	-	M	-	-	-	Outer membrane protein beta-barrel domain
HELMLDPP_04006	1.77e-238	-	-	-	T	-	-	-	Histidine kinase
HELMLDPP_04007	2.8e-185	-	-	-	K	-	-	-	LytTr DNA-binding domain protein
HELMLDPP_04008	0.0	-	-	-	M	-	-	-	Belongs to the glycosyl hydrolase 28 family
HELMLDPP_04009	8.14e-203	-	-	-	G	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04010	1.06e-193	murQ	4.2.1.126	-	H	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HELMLDPP_04011	2.39e-163	-	-	-	S	ko:K09797	-	ko00000	Protein of unknown function (DUF541)
HELMLDPP_04012	0.0	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence
HELMLDPP_04013	2.22e-81	cspG	-	-	K	-	-	-	Cold-shock DNA-binding domain protein
HELMLDPP_04014	5.77e-200	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HELMLDPP_04015	3.96e-126	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_04016	2.62e-87	-	-	-	S	-	-	-	COG NOG23405 non supervised orthologous group
HELMLDPP_04017	4.05e-93	-	-	-	S	-	-	-	COG NOG28735 non supervised orthologous group
HELMLDPP_04018	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_04019	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	SusD family
HELMLDPP_04020	2.8e-185	mazG	3.6.1.66	-	S	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_04021	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HELMLDPP_04022	2.36e-100	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score 9.46
HELMLDPP_04023	2.77e-116	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HELMLDPP_04024	5.8e-70	-	-	-	-	-	-	-	-
HELMLDPP_04025	3.2e-95	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04026	6.88e-232	-	-	-	S	-	-	-	COG NOG26558 non supervised orthologous group
HELMLDPP_04027	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HELMLDPP_04028	0.0	pafA	-	-	P	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HELMLDPP_04029	8.2e-289	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_04030	1.69e-172	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HELMLDPP_04031	0.0	-	-	-	I	-	-	-	Psort location OuterMembrane, score
HELMLDPP_04032	0.0	-	-	-	S	-	-	-	Tetratricopeptide repeat protein
HELMLDPP_04033	1.06e-152	-	-	-	S	-	-	-	Lipopolysaccharide-assembly, LptC-related
HELMLDPP_04034	8.91e-289	tlyC	-	-	S	ko:K03699	-	ko00000,ko02042	Psort location CytoplasmicMembrane, score
HELMLDPP_04035	0.0	ppiD	5.2.1.8	-	O	ko:K01802,ko:K03770	-	ko00000,ko01000,ko03110	COG NOG26630 non supervised orthologous group
HELMLDPP_04037	9.99e-98	-	-	-	S	-	-	-	COG NOG30410 non supervised orthologous group
HELMLDPP_04038	1.1e-279	madB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	COG COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
HELMLDPP_04039	1.08e-271	-	-	-	M	-	-	-	Gram-negative bacterial TonB protein C-terminal
HELMLDPP_04040	2.04e-253	ilvC	1.1.1.86	-	E	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	ketol-acid reductoisomerase
HELMLDPP_04041	8.74e-182	-	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HELMLDPP_04042	5.82e-124	ilvN	2.2.1.6	-	E	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	synthase small subunit
HELMLDPP_04043	0.0	ilvB	2.2.1.6	-	H	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetolactate synthase, large subunit
HELMLDPP_04044	0.0	ilvD	4.2.1.9	-	H	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the IlvD Edd family
HELMLDPP_04045	3.46e-78	-	-	-	S	-	-	-	COG NOG30654 non supervised orthologous group
HELMLDPP_04046	4.25e-128	slyD	5.2.1.8	-	G	ko:K03775	-	ko00000,ko01000,ko03110	Psort location Cytoplasmic, score
HELMLDPP_04047	1.65e-308	-	-	-	S	-	-	-	DNA-binding protein with the Helix-hairpin-helix motif
HELMLDPP_04048	6.95e-192	-	-	-	L	-	-	-	DNA metabolism protein
HELMLDPP_04049	1.99e-197	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HELMLDPP_04050	1.15e-161	-	-	-	S	-	-	-	COG NOG26960 non supervised orthologous group
HELMLDPP_04051	9.39e-232	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein
HELMLDPP_04052	2.22e-229	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HELMLDPP_04053	5.91e-179	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HELMLDPP_04054	5.47e-180	aroE	1.1.1.25	-	C	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG0169 Shikimate 5-dehydrogenase
HELMLDPP_04055	1.92e-240	-	-	-	S	ko:K06889	-	ko00000	of the alpha beta superfamily
HELMLDPP_04056	7.03e-197	-	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HELMLDPP_04057	1.12e-130	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HELMLDPP_04058	6.94e-262	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HELMLDPP_04059	0.0	dapE	-	-	E	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04060	7.5e-146	-	-	-	C	-	-	-	Nitroreductase family
HELMLDPP_04061	1.54e-16	-	-	-	-	-	-	-	-
HELMLDPP_04062	6.43e-66	-	-	-	-	-	-	-	-
HELMLDPP_04063	4.25e-128	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HELMLDPP_04064	1.58e-301	pbuX	-	-	F	ko:K16345	-	ko00000,ko02000	xanthine permease
HELMLDPP_04065	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04066	8.49e-206	hddC	-	-	JM	-	-	-	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon)
HELMLDPP_04067	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score
HELMLDPP_04068	3.73e-99	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HELMLDPP_04069	7.92e-129	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_04071	1.28e-176	-	-	-	-	-	-	-	-
HELMLDPP_04072	8.75e-138	-	-	-	-	-	-	-	-
HELMLDPP_04073	0.0	-	-	-	E	ko:K03312	-	ko00000,ko02000	Sodium/glutamate symporter
HELMLDPP_04074	1.21e-114	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04075	1.9e-169	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04076	1.93e-241	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04077	1.19e-263	-	-	-	L	-	-	-	Phage integrase SAM-like domain
HELMLDPP_04078	1.15e-198	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04079	3.39e-11	-	-	-	-	-	-	-	-
HELMLDPP_04080	1.34e-225	-	-	-	-	-	-	-	-
HELMLDPP_04082	4.67e-147	-	-	-	-	-	-	-	-
HELMLDPP_04083	7.27e-237	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3871)
HELMLDPP_04084	1.88e-52	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HELMLDPP_04085	1.32e-61	-	-	-	S	ko:K19158	-	ko00000,ko01000,ko02048	YoeB-like toxin of bacterial type II toxin-antitoxin system
HELMLDPP_04086	8.87e-18	-	-	-	L	ko:K03630	-	ko00000	DNA repair
HELMLDPP_04087	3.89e-132	-	-	-	L	-	-	-	Phage integrase family
HELMLDPP_04088	1.93e-12	-	-	-	-	-	-	-	-
HELMLDPP_04089	5.71e-159	-	-	-	-	-	-	-	-
HELMLDPP_04090	6.22e-243	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
HELMLDPP_04091	1.58e-10	-	-	-	-	-	-	-	-
HELMLDPP_04092	1.96e-253	-	-	-	S	-	-	-	Domain of unknown function (DUF4857)
HELMLDPP_04093	3.15e-154	-	-	-	-	-	-	-	-
HELMLDPP_04094	4.59e-217	-	-	-	V	ko:K01990,ko:K19340	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1131 ABC-type multidrug transport system ATPase component
HELMLDPP_04095	5.59e-139	-	-	-	S	ko:K09939	-	ko00000	Putative PepSY_TM-like
HELMLDPP_04096	1.41e-129	-	-	-	-	-	-	-	-
HELMLDPP_04097	0.0	-	-	-	-	-	-	-	-
HELMLDPP_04098	1.07e-299	-	-	-	S	-	-	-	Protein of unknown function (DUF4876)
HELMLDPP_04099	0.0	-	-	-	P	-	-	-	TonB-dependent Receptor Plug Domain
HELMLDPP_04100	8.3e-57	-	-	-	-	-	-	-	-
HELMLDPP_04101	6.28e-84	-	-	-	-	-	-	-	-
HELMLDPP_04102	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HELMLDPP_04103	6.72e-152	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HELMLDPP_04104	0.0	-	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HELMLDPP_04105	4.54e-144	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HELMLDPP_04106	8.82e-124	-	-	-	CO	-	-	-	Redoxin
HELMLDPP_04107	6.36e-277	ynfM	-	-	EGP	ko:K08224	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04108	4.04e-52	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_04109	1.49e-299	-	-	-	S	-	-	-	COG NOG26961 non supervised orthologous group
HELMLDPP_04110	3.6e-241	ldhA	1.1.1.28	-	C	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HELMLDPP_04111	1.54e-137	maf	-	-	D	ko:K06287	-	ko00000	COG0424 Nucleotide-binding protein implicated in inhibition of septum formation
HELMLDPP_04112	3.45e-126	kdsC	3.1.3.45	-	S	ko:K03270	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family
HELMLDPP_04113	9.72e-185	-	-	-	S	-	-	-	NADP oxidoreductase coenzyme F420-dependent
HELMLDPP_04114	1.19e-66	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HELMLDPP_04115	2.49e-122	-	-	-	C	-	-	-	Nitroreductase family
HELMLDPP_04116	2.48e-255	-	-	-	V	-	-	-	COG NOG22551 non supervised orthologous group
HELMLDPP_04117	3.06e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_04118	0.0	mmdA	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HELMLDPP_04119	3.35e-217	-	-	-	C	-	-	-	Lamin Tail Domain
HELMLDPP_04120	6.56e-92	mmdC	-	-	I	-	-	-	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HELMLDPP_04121	2.85e-266	oadB	4.1.1.3	-	C	ko:K01572	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000,ko02000	sodium ion-translocating decarboxylase, beta subunit
HELMLDPP_04122	3.84e-51	-	-	-	G	-	-	-	Cyclo-malto-dextrinase C-terminal domain
HELMLDPP_04123	1.09e-173	ydfG	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HELMLDPP_04124	9.22e-210	-	3.1.2.12	CE1	S	ko:K01070	ko00680,ko01120,ko01200,map00680,map01120,map01200	ko00000,ko00001,ko01000	esterase
HELMLDPP_04125	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04126	1.39e-101	-	-	-	P	ko:K03711	-	ko00000,ko03000	Psort location Cytoplasmic, score 8.96
HELMLDPP_04127	6.96e-286	-	-	-	I	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04128	1.49e-132	-	-	-	T	-	-	-	Cyclic nucleotide-binding domain protein
HELMLDPP_04130	1.86e-72	-	-	-	-	-	-	-	-
HELMLDPP_04131	1.36e-76	-	-	-	S	-	-	-	Bacterial PH domain
HELMLDPP_04134	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HELMLDPP_04135	8.67e-265	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_04136	9.4e-32	-	-	-	S	-	-	-	COG3943, virulence protein
HELMLDPP_04137	3.42e-180	-	-	-	Q	-	-	-	Nodulation protein S (NodS)
HELMLDPP_04138	1.43e-147	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HELMLDPP_04139	7.25e-123	-	-	-	F	-	-	-	adenylate kinase activity
HELMLDPP_04140	1.61e-125	-	-	-	K	ko:K03088	-	ko00000,ko03021	RNA polymerase sigma-70 factor
HELMLDPP_04141	5.44e-277	-	-	-	PT	-	-	-	Sigma factor regulatory protein, FecR PupR family
HELMLDPP_04142	0.0	-	-	-	P	-	-	-	non supervised orthologous group
HELMLDPP_04143	0.0	-	-	-	E	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_04144	1.41e-13	-	-	-	-	-	-	-	-
HELMLDPP_04145	6.7e-286	-	-	-	T	-	-	-	COG COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases
HELMLDPP_04146	3.55e-300	sdaA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	COG1760 L-serine deaminase
HELMLDPP_04147	1.95e-99	-	-	-	S	-	-	-	COG NOG31508 non supervised orthologous group
HELMLDPP_04148	5.57e-129	-	-	-	S	-	-	-	COG NOG28695 non supervised orthologous group
HELMLDPP_04149	3.53e-158	ktrA	-	-	C	ko:K03499	-	ko00000,ko02000	Psort location Cytoplasmic, score 8.96
HELMLDPP_04150	0.0	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04151	0.0	trpB	4.2.1.20	-	E	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HELMLDPP_04152	1.36e-205	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HELMLDPP_04153	5.99e-312	-	-	-	S	-	-	-	COG NOG10142 non supervised orthologous group
HELMLDPP_04155	1.99e-281	-	-	-	CO	-	-	-	Domain of unknown function (DUF4369)
HELMLDPP_04156	0.0	-	-	-	S	ko:K21572	-	ko00000,ko02000	Starch-binding associating with outer membrane
HELMLDPP_04157	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_04158	0.0	-	-	-	K	-	-	-	transcriptional regulator (AraC
HELMLDPP_04159	4.25e-150	queH	1.17.99.6	-	C	ko:K09765	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HELMLDPP_04160	0.0	-	-	-	P	ko:K03281	-	ko00000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04161	2.31e-69	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HELMLDPP_04162	0.0	cdr	-	-	P	-	-	-	Belongs to the sulfur carrier protein TusA family
HELMLDPP_04163	3.84e-313	-	-	-	V	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04164	0.0	-	-	-	P	-	-	-	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04165	1.41e-89	ydiI	3.1.2.28	-	Q	ko:K19222	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Thioesterase superfamily
HELMLDPP_04166	9.92e-280	entC	5.4.4.2	-	HQ	ko:K02361,ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HELMLDPP_04167	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HELMLDPP_04168	5.72e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HELMLDPP_04169	1.45e-76	-	-	-	S	-	-	-	YjbR
HELMLDPP_04170	1.46e-264	menC	-	-	M	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04171	7.52e-263	menE	6.2.1.26	-	IQ	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_04172	1.36e-211	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_04173	2.19e-35	-	-	-	S	-	-	-	COG NOG17973 non supervised orthologous group
HELMLDPP_04174	0.0	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
HELMLDPP_04175	7.41e-97	-	-	-	-	-	-	-	-
HELMLDPP_04176	6.82e-139	-	-	-	S	-	-	-	VirE N-terminal domain
HELMLDPP_04177	0.0	-	-	-	L	-	-	-	Primase C terminal 2 (PriCT-2)
HELMLDPP_04178	6.02e-49	-	-	-	S	-	-	-	Domain of unknown function (DUF4248)
HELMLDPP_04179	3.67e-120	-	-	-	L	-	-	-	regulation of translation
HELMLDPP_04180	1.46e-127	-	-	-	V	-	-	-	Ami_2
HELMLDPP_04181	7.85e-189	-	-	-	L	-	-	-	Phage integrase family
HELMLDPP_04182	4.1e-112	-	-	-	-	-	-	-	-
HELMLDPP_04183	1.36e-266	-	-	-	U	-	-	-	Relaxase mobilization nuclease domain protein
HELMLDPP_04184	3.88e-75	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04185	7.8e-238	-	-	-	L	-	-	-	COG NOG08810 non supervised orthologous group
HELMLDPP_04186	1.47e-304	-	-	-	S	-	-	-	COG NOG11635 non supervised orthologous group
HELMLDPP_04187	3.15e-78	-	-	-	K	-	-	-	Helix-turn-helix domain
HELMLDPP_04190	1.24e-66	-	-	-	N	ko:K02238	-	ko00000,ko00002,ko02044	competence protein COMEC
HELMLDPP_04192	5.2e-292	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HELMLDPP_04193	6.05e-127	-	-	-	L	-	-	-	DNA binding domain, excisionase family
HELMLDPP_04194	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HELMLDPP_04195	1.19e-187	-	-	-	O	-	-	-	META domain
HELMLDPP_04196	1.43e-297	-	-	-	-	-	-	-	-
HELMLDPP_04197	1.11e-305	LYS1	1.5.1.7	-	E	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	COG1748 Saccharopine dehydrogenase and related
HELMLDPP_04198	2.09e-104	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	bacterioferritin comigratory protein
HELMLDPP_04199	3.89e-242	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HELMLDPP_04200	4.37e-135	-	-	-	S	-	-	-	COG NOG28221 non supervised orthologous group
HELMLDPP_04201	0.0	-	-	-	M	ko:K21572	-	ko00000,ko02000	Pfam:SusD
HELMLDPP_04202	0.0	-	-	-	P	-	-	-	TonB-linked outer membrane protein, SusC RagA family
HELMLDPP_04203	3.33e-205	-	-	-	G	-	-	-	Glycosyl hydrolase family 16
HELMLDPP_04204	0.0	-	-	-	KT	-	-	-	helix_turn_helix, arabinose operon control protein
HELMLDPP_04205	4.34e-200	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HELMLDPP_04206	4.47e-108	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HELMLDPP_04207	1.92e-250	-	-	-	S	-	-	-	Endonuclease Exonuclease phosphatase family
HELMLDPP_04208	0.0	pepD_1	-	-	E	ko:K01270	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Psort location Cytoplasmic, score 8.96
HELMLDPP_04209	1.37e-41	-	-	-	S	-	-	-	COG NOG35566 non supervised orthologous group
HELMLDPP_04210	5.88e-131	-	-	-	M	ko:K06142	-	ko00000	membrane
HELMLDPP_04211	1.12e-64	-	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Psort location Cytoplasmic, score
HELMLDPP_04212	2.52e-107	-	-	-	O	-	-	-	Thioredoxin-like domain
HELMLDPP_04213	2.8e-135	rbr3A	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04214	2.14e-100	fur	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HELMLDPP_04215	0.0	nadE	6.3.5.1	-	H	ko:K01950	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HELMLDPP_04216	1.1e-281	hisB	3.1.3.15, 4.2.1.19	-	E	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidine biosynthesis bifunctional protein HisB
HELMLDPP_04217	2.91e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HELMLDPP_04218	7.78e-298	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HELMLDPP_04219	1.05e-191	hisG	2.4.2.17	-	F	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	ATP phosphoribosyltransferase
HELMLDPP_04220	1.27e-119	-	-	-	Q	-	-	-	Thioesterase superfamily
HELMLDPP_04221	1.46e-65	-	-	-	S	-	-	-	Stress responsive A B barrel domain protein
HELMLDPP_04222	5.53e-145	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score
HELMLDPP_04223	0.0	mltF	-	-	M	ko:K18691	-	ko00000,ko01000,ko01011	soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein
HELMLDPP_04224	2.5e-95	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HELMLDPP_04225	3.02e-73	-	-	-	-	-	-	-	-
HELMLDPP_04226	4.91e-78	-	-	-	-	-	-	-	-
HELMLDPP_04227	2.04e-112	-	-	-	-	-	-	-	-
HELMLDPP_04228	1.21e-169	-	-	-	K	-	-	-	BRO family, N-terminal domain
HELMLDPP_04230	2.7e-17	-	-	-	-	-	-	-	-
HELMLDPP_04231	5.44e-104	-	-	-	-	-	-	-	-
HELMLDPP_04232	1.33e-100	-	-	-	S	-	-	-	Domain of unknown function, B. Theta Gene description (DUF3872)
HELMLDPP_04233	3.14e-122	-	-	-	S	-	-	-	Conjugative transposon protein TraO
HELMLDPP_04234	8.03e-192	-	-	-	U	-	-	-	Domain of unknown function (DUF4138)
HELMLDPP_04235	3.34e-47	traM	-	-	S	-	-	-	Conjugative transposon, TraM
HELMLDPP_04236	4.52e-80	traM	-	-	S	-	-	-	Conjugative transposon, TraM
HELMLDPP_04237	4.9e-109	-	-	-	U	-	-	-	Conjugative transposon TraK protein
HELMLDPP_04238	6.73e-223	-	-	-	S	-	-	-	Homologues of TraJ from Bacteroides conjugative transposon
HELMLDPP_04239	2.02e-129	-	-	-	U	-	-	-	Domain of unknown function (DUF4141)
HELMLDPP_04240	1.16e-306	-	-	-	U	-	-	-	Conjugation system ATPase, TraG family
HELMLDPP_04244	1.04e-289	nspC	4.1.1.96	-	E	ko:K13747	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko01000	Psort location Cytoplasmic, score 8.96
HELMLDPP_04245	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HELMLDPP_04246	1.31e-153	sodB	1.15.1.1	-	C	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HELMLDPP_04247	1.04e-41	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine biosynthesis protein ThiS
HELMLDPP_04248	3.44e-146	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HELMLDPP_04249	1.23e-177	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HELMLDPP_04250	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HELMLDPP_04251	3.88e-123	-	-	-	S	-	-	-	COG NOG35345 non supervised orthologous group
HELMLDPP_04252	6.3e-140	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04253	1.83e-282	thiH	4.1.99.19	-	C	ko:K03150	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Thiazole biosynthesis protein ThiH
HELMLDPP_04254	3.22e-163	moeZ	2.7.7.80, 2.8.1.11	-	H	ko:K21029,ko:K21147	ko04122,map04122	ko00000,ko00001,ko01000	involved in molybdopterin and thiamine biosynthesis family 2
HELMLDPP_04255	3.58e-288	-	-	-	E	-	-	-	Glutathionylspermidine synthase preATP-grasp
HELMLDPP_04256	2.5e-79	-	-	-	-	-	-	-	-
HELMLDPP_04258	5.55e-149	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Thiamine monophosphate synthase TENI
HELMLDPP_04259	8.75e-215	prs	2.7.6.1	-	EF	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG0462 Phosphoribosylpyrophosphate synthetase
HELMLDPP_04260	0.0	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location Periplasmic, score 9.44
HELMLDPP_04261	5.98e-172	ydcV	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HELMLDPP_04262	1.23e-181	-	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Psort location CytoplasmicMembrane, score 10.00
HELMLDPP_04263	0.0	potA	3.6.3.29, 3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K02017,ko:K10112,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HELMLDPP_04264	1.05e-59	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HELMLDPP_04265	1.16e-142	-	-	-	T	-	-	-	PAS domain S-box protein
HELMLDPP_04267	1.17e-267	-	-	-	O	-	-	-	Antioxidant, AhpC TSA family
HELMLDPP_04268	0.0	glgP	2.4.1.1, 2.4.1.11, 2.4.1.8	GH65,GT3,GT35	G	ko:K00688,ko:K00691,ko:K16153	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	COG0058 Glucan phosphorylase
HELMLDPP_04269	0.0	-	2.4.1.11	GT3	G	ko:K00693	ko00500,ko01100,ko04151,ko04152,ko04910,ko04922,ko04931,map00500,map01100,map04151,map04152,map04910,map04922,map04931	ko00000,ko00001,ko01000,ko01003	Starch synthase
HELMLDPP_04270	1.62e-95	ntpK	-	-	C	ko:K02124	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG COG0636 F0F1-type ATP synthase, subunit c Archaeal vacuolar-type H -ATPase, subunit K
HELMLDPP_04271	0.0	-	-	-	C	ko:K02123	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Belongs to the V-ATPase 116 kDa subunit family
HELMLDPP_04272	1.76e-131	-	-	-	C	ko:K02120	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Psort location Cytoplasmic, score 8.96
HELMLDPP_04273	3.78e-316	ntpB	-	-	C	ko:K02118	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	the B subunit is part of the catalytic core of the ATP synthase complex
HELMLDPP_04274	0.0	atpA	3.6.3.14, 3.6.3.15	-	C	ko:K02117	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HELMLDPP_04275	1.15e-197	-	-	-	C	-	-	-	Psort location Cytoplasmic, score 8.96
HELMLDPP_04276	1.77e-108	-	-	-	C	ko:K02121	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Produces ATP from ADP in the presence of a proton gradient across the membrane