ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HEHGKEEJ_00001 8.13e-153 - - - L ko:K07497 - ko00000 PFAM Integrase catalytic region
HEHGKEEJ_00002 1.56e-59 - - - L ko:K07483,ko:K09936 ko02024,map02024 ko00000,ko00001,ko02000 Helix-turn-helix domain
HEHGKEEJ_00003 3.49e-192 cpsY - - K - - - Transcriptional regulator, LysR family
HEHGKEEJ_00004 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HEHGKEEJ_00005 1.76e-162 metF 1.5.1.20 - C ko:K00297 ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Methylenetetrahydrofolate reductase
HEHGKEEJ_00006 9.78e-148 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEHGKEEJ_00007 1.06e-48 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEHGKEEJ_00008 5.53e-24 - - - M - - - Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HEHGKEEJ_00009 3.65e-90 - - - - - - - -
HEHGKEEJ_00010 1.18e-72 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEHGKEEJ_00011 4.69e-17 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HEHGKEEJ_00012 8.77e-89 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HEHGKEEJ_00013 1.94e-135 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HEHGKEEJ_00014 9.52e-284 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEHGKEEJ_00015 1.12e-131 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HEHGKEEJ_00016 4.1e-265 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HEHGKEEJ_00017 4.63e-174 - - - L ko:K07497 - ko00000 hmm pf00665
HEHGKEEJ_00018 1.47e-91 - - - L - - - Helix-turn-helix domain
HEHGKEEJ_00019 1.78e-83 - - - - - - - -
HEHGKEEJ_00020 1.68e-11 - - - - - - - -
HEHGKEEJ_00021 5.14e-155 - - - - ko:K01992 - ko00000,ko00002,ko02000 -
HEHGKEEJ_00022 4.99e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HEHGKEEJ_00023 1.18e-271 - - - EGP - - - Major Facilitator
HEHGKEEJ_00024 0.0 - - - G ko:K02775 ko00052,ko01100,ko02060,map00052,map01100,map02060 ko00000,ko00001,ko00002,ko02000 PTS system Galactitol-specific IIC component
HEHGKEEJ_00025 6.59e-229 - - - C - - - Zinc-binding dehydrogenase
HEHGKEEJ_00026 1.47e-208 - - - - - - - -
HEHGKEEJ_00027 1.3e-95 - - - K - - - Transcriptional regulator
HEHGKEEJ_00028 8.47e-240 ybcH - - D ko:K06889 - ko00000 Alpha beta
HEHGKEEJ_00029 1.5e-67 - - - S ko:K08987 - ko00000 Protein of unknown function (DUF1304)
HEHGKEEJ_00030 0.0 nhaK - - P ko:K03316 - ko00000 Sodium proton antiporter
HEHGKEEJ_00031 6.5e-71 - - - - - - - -
HEHGKEEJ_00032 1.75e-148 - - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEHGKEEJ_00033 9.04e-317 - - - S ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_00034 8.25e-125 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HEHGKEEJ_00035 1.03e-171 - - - S ko:K07090 - ko00000 membrane transporter protein
HEHGKEEJ_00036 7.24e-204 endA - - V ko:K15051 - ko00000 DNA/RNA non-specific endonuclease
HEHGKEEJ_00037 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HEHGKEEJ_00040 5.2e-129 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEHGKEEJ_00041 3.31e-284 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HEHGKEEJ_00042 3.41e-296 - - - N ko:K09384 - ko00000 Uncharacterized conserved protein (DUF2075)
HEHGKEEJ_00043 2.9e-158 - - - S - - - SNARE associated Golgi protein
HEHGKEEJ_00044 0.0 uvrA2 - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 excinuclease ABC, A subunit
HEHGKEEJ_00045 1.27e-72 crcB - - U ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEHGKEEJ_00046 7.82e-80 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEHGKEEJ_00047 3.39e-90 - - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HEHGKEEJ_00048 4.15e-192 - - - S - - - DUF218 domain
HEHGKEEJ_00049 0.0 ubiB - - S ko:K03688 - ko00000 ABC1 family
HEHGKEEJ_00050 9.45e-315 yhdP - - S - - - Transporter associated domain
HEHGKEEJ_00051 3.35e-77 - - - M - - - CHAP domain
HEHGKEEJ_00055 4.18e-59 - - - L - - - Initiator Replication protein
HEHGKEEJ_00056 8.16e-54 - - - - - - - -
HEHGKEEJ_00060 3.72e-183 - - - U - - - TraM recognition site of TraD and TraG
HEHGKEEJ_00065 1.78e-39 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HEHGKEEJ_00066 2.17e-56 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HEHGKEEJ_00067 1.89e-36 arsC 1.20.4.1 - T ko:K03741 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEHGKEEJ_00068 1.17e-212 arsB - - P ko:K03325 - ko00000,ko02000 Sodium Bile acid symporter family
HEHGKEEJ_00069 2.26e-46 arsR - - K ko:K03892 - ko00000,ko03000 helix_turn_helix, Arsenical Resistance Operon Repressor
HEHGKEEJ_00071 1.39e-82 repB - - L - - - Initiator Replication protein
HEHGKEEJ_00072 1.11e-285 - - - - - - - -
HEHGKEEJ_00074 2.1e-50 - - - K - - - Helix-turn-helix domain
HEHGKEEJ_00075 2.2e-70 - - - S - - - Phage derived protein Gp49-like (DUF891)
HEHGKEEJ_00076 3.66e-120 - - - L - - - Integrase
HEHGKEEJ_00077 4.53e-212 - - - I - - - alpha/beta hydrolase fold
HEHGKEEJ_00078 2.23e-150 frnE 5.3.4.1 - Q ko:K01829 - ko00000,ko01000 DSBA-like thioredoxin domain
HEHGKEEJ_00079 6.39e-73 - - - - - - - -
HEHGKEEJ_00088 1.04e-172 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HEHGKEEJ_00089 5.87e-181 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 alpha subunit
HEHGKEEJ_00090 7.2e-185 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HEHGKEEJ_00091 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Acetyl-CoA carboxylase biotin carboxylase subunit
HEHGKEEJ_00092 1.38e-98 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEHGKEEJ_00093 1.3e-99 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HEHGKEEJ_00094 1.27e-288 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HEHGKEEJ_00095 7.69e-170 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HEHGKEEJ_00096 3.03e-207 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 Malonyl CoA-acyl carrier protein transacylase
HEHGKEEJ_00097 2.51e-47 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEHGKEEJ_00098 4.83e-229 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HEHGKEEJ_00099 2.35e-101 - - - K - - - Transcriptional regulator, MarR family
HEHGKEEJ_00100 1.76e-94 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HEHGKEEJ_00102 8.4e-259 xerS - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_00103 2.82e-109 - - - M - - - biosynthesis protein
HEHGKEEJ_00104 5.46e-235 cps3F - - - - - - -
HEHGKEEJ_00105 1.67e-129 - - - S - - - enterobacterial common antigen metabolic process
HEHGKEEJ_00107 1.48e-148 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HEHGKEEJ_00108 4.27e-162 - - - M - - - transferase activity, transferring glycosyl groups
HEHGKEEJ_00109 1.98e-190 - - GT4 M ko:K02840 ko00540,ko01100,map00540,map01100 ko00000,ko00001,ko00002,ko01000,ko01003,ko01005 Glycosyl transferases group 1
HEHGKEEJ_00110 2.44e-304 cps1C - - S ko:K03328 - ko00000 Membrane protein involved in the export of O-antigen and teichoic acid
HEHGKEEJ_00111 5.62e-275 glf 5.4.99.9 - M ko:K01854 ko00052,ko00520,map00052,map00520 ko00000,ko00001,ko01000 UDP-galactopyranose mutase
HEHGKEEJ_00112 3.3e-152 - - - M - - - Bacterial sugar transferase
HEHGKEEJ_00113 4.82e-226 yfdH - GT2 M ko:K12999 - ko00000,ko01000,ko01003,ko01005 Glycosyltransferase, group 2 family protein
HEHGKEEJ_00114 1.71e-192 cps1D - - M - - - Domain of unknown function (DUF4422)
HEHGKEEJ_00115 1.61e-181 recX - - S ko:K03565 - ko00000,ko03400 Regulatory protein RecX
HEHGKEEJ_00116 2.53e-42 - - - - - - - -
HEHGKEEJ_00117 1.26e-46 - - - S - - - Protein of unknown function (DUF2922)
HEHGKEEJ_00118 1.23e-197 rbn - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HEHGKEEJ_00119 2.79e-253 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Lactonase, 7-bladed beta-propeller
HEHGKEEJ_00120 3.61e-209 rrmA 2.1.1.187 - H ko:K00563,ko:K10947 - ko00000,ko01000,ko03000,ko03009 Methyltransferase
HEHGKEEJ_00121 2.64e-124 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HEHGKEEJ_00122 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HEHGKEEJ_00123 4.47e-16 - - - S - - - Protein of unknown function (DUF4044)
HEHGKEEJ_00124 1.6e-77 - - - - - - - -
HEHGKEEJ_00125 1.5e-101 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HEHGKEEJ_00126 4.61e-224 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HEHGKEEJ_00127 5.99e-74 ftsL - - D - - - Cell division protein FtsL
HEHGKEEJ_00128 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEHGKEEJ_00129 5.44e-230 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HEHGKEEJ_00130 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HEHGKEEJ_00131 2.16e-262 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HEHGKEEJ_00132 6.38e-197 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HEHGKEEJ_00133 0.0 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HEHGKEEJ_00134 6.52e-289 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HEHGKEEJ_00135 1.57e-92 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HEHGKEEJ_00136 1.11e-54 ylmG - - S ko:K02221 - ko00000,ko02044 YGGT family
HEHGKEEJ_00137 1.84e-190 ylmH - - S - - - S4 domain protein
HEHGKEEJ_00138 6.11e-108 divIVA - - D ko:K04074 - ko00000,ko03036 DivIVA domain protein
HEHGKEEJ_00139 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HEHGKEEJ_00140 5.69e-44 cspB - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEHGKEEJ_00141 2.48e-129 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HEHGKEEJ_00142 1.54e-33 - - - - - - - -
HEHGKEEJ_00143 3.4e-162 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HEHGKEEJ_00144 9.43e-280 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HEHGKEEJ_00145 5.58e-76 XK27_04120 - - S - - - Putative amino acid metabolism
HEHGKEEJ_00146 4.35e-286 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HEHGKEEJ_00147 1.99e-159 pgm6 - - G - - - phosphoglycerate mutase
HEHGKEEJ_00148 1.1e-156 - - - S - - - repeat protein
HEHGKEEJ_00149 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HEHGKEEJ_00150 1.04e-223 prs2 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEHGKEEJ_00151 1.53e-241 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HEHGKEEJ_00152 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HEHGKEEJ_00153 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HEHGKEEJ_00154 1.2e-114 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HEHGKEEJ_00155 4.19e-286 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HEHGKEEJ_00156 5.62e-224 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HEHGKEEJ_00157 1.62e-183 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HEHGKEEJ_00158 1.84e-282 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEHGKEEJ_00159 1.56e-255 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HEHGKEEJ_00160 4.66e-103 - - - KT ko:K02647 - ko00000,ko03000 Putative sugar diacid recognition
HEHGKEEJ_00161 7.73e-280 yojA - - EG ko:K03299 - ko00000,ko02000 GntP family permease
HEHGKEEJ_00162 1.73e-270 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HEHGKEEJ_00163 5.28e-76 - - - - - - - -
HEHGKEEJ_00165 2.97e-249 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NlpC P60 family protein
HEHGKEEJ_00166 4.37e-39 - - - - - - - -
HEHGKEEJ_00167 2.71e-235 - - - I - - - Diacylglycerol kinase catalytic
HEHGKEEJ_00168 9.99e-44 ykzG - - S - - - Belongs to the UPF0356 family
HEHGKEEJ_00169 2.79e-107 - - - - - - - -
HEHGKEEJ_00170 8.3e-134 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HEHGKEEJ_00171 2.44e-267 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Dehydrogenase E1 component
HEHGKEEJ_00172 6.63e-232 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 Transketolase, C-terminal domain protein
HEHGKEEJ_00173 1.34e-314 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HEHGKEEJ_00174 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 Dehydrogenase
HEHGKEEJ_00175 2.87e-63 yktA - - S - - - Belongs to the UPF0223 family
HEHGKEEJ_00176 1.74e-177 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the inositol monophosphatase superfamily
HEHGKEEJ_00177 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HEHGKEEJ_00178 2.75e-286 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HEHGKEEJ_00179 3.83e-61 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2129)
HEHGKEEJ_00180 2.37e-129 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 RNA methyltransferase, RsmD family
HEHGKEEJ_00181 3.05e-116 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HEHGKEEJ_00182 2.58e-253 lon - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HEHGKEEJ_00183 8.7e-141 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 Competence protein ComEA
HEHGKEEJ_00184 5e-116 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HEHGKEEJ_00185 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HEHGKEEJ_00186 5.84e-203 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HEHGKEEJ_00187 1.44e-47 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HEHGKEEJ_00188 1.74e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HEHGKEEJ_00189 0.0 rnjB - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEHGKEEJ_00190 1.52e-209 - - - S - - - Tetratricopeptide repeat
HEHGKEEJ_00191 4.94e-288 tuf - - J ko:K02358,ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HEHGKEEJ_00192 5.54e-303 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HEHGKEEJ_00193 5.06e-298 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HEHGKEEJ_00194 2.01e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HEHGKEEJ_00195 1.11e-78 - - - S - - - mazG nucleotide pyrophosphohydrolase
HEHGKEEJ_00196 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEHGKEEJ_00197 2.93e-125 - - - K - - - Acetyltransferase (GNAT) domain
HEHGKEEJ_00198 3.8e-63 - - - - - - - -
HEHGKEEJ_00199 2.58e-41 - - - - - - - -
HEHGKEEJ_00200 0.0 nylA 3.5.1.4 - J ko:K01426 ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120 ko00000,ko00001,ko01000 Belongs to the amidase family
HEHGKEEJ_00201 1.26e-60 - - - - - - - -
HEHGKEEJ_00202 2.75e-105 - - - S - - - Protein of unknown function (DUF805)
HEHGKEEJ_00203 1.48e-178 butA 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HEHGKEEJ_00204 0.0 hsdR 3.1.21.3 - V ko:K01153 - ko00000,ko01000,ko02048 Subunit R is required for both nuclease and ATPase activities, but not for modification
HEHGKEEJ_00205 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 type I restriction-modification system
HEHGKEEJ_00206 7.65e-67 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HEHGKEEJ_00207 2.77e-51 axe - - K ko:K21498 - ko00000,ko02048 Helix-turn-helix XRE-family like proteins
HEHGKEEJ_00208 1.29e-59 - - - S ko:K07334 - ko00000,ko02048 RelE-like toxin of type II toxin-antitoxin system HigB
HEHGKEEJ_00209 1.14e-67 - 3.1.21.3 - V ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
HEHGKEEJ_00210 1.07e-52 hxlR - - K - - - regulation of RNA biosynthetic process
HEHGKEEJ_00211 1.72e-212 - - - G - - - Belongs to the carbohydrate kinase PfkB family
HEHGKEEJ_00212 0.0 - - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HEHGKEEJ_00213 2.34e-266 - - - O - - - ADP-ribosylglycohydrolase
HEHGKEEJ_00214 3.53e-135 pncA - - Q - - - Isochorismatase family
HEHGKEEJ_00215 0.0 nadC2 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEHGKEEJ_00216 1.39e-169 - - - F - - - NUDIX domain
HEHGKEEJ_00218 3.87e-112 - - - - - - - -
HEHGKEEJ_00219 3.11e-147 - - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_00225 4.39e-94 - - - K - - - Transcriptional regulator, TetR family
HEHGKEEJ_00226 1.64e-18 - - - K - - - Transcriptional regulator, TetR family
HEHGKEEJ_00227 5.46e-315 - - - E - - - amino acid
HEHGKEEJ_00228 8.71e-178 puuD - - S ko:K07010 - ko00000,ko01002 peptidase C26
HEHGKEEJ_00229 4.72e-107 - - - L ko:K07491 - ko00000 Transposase IS200 like
HEHGKEEJ_00230 3.33e-304 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HEHGKEEJ_00232 1.14e-123 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HEHGKEEJ_00233 2.31e-131 - - - - - - - -
HEHGKEEJ_00234 0.0 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HEHGKEEJ_00235 2.95e-239 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEHGKEEJ_00236 0.0 nox 1.6.3.4 - C ko:K17869 - ko00000,ko01000 NADH oxidase
HEHGKEEJ_00237 6.51e-114 - - - S - - - ECF-type riboflavin transporter, S component
HEHGKEEJ_00238 0.0 glpQ 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 Membrane domain of glycerophosphoryl diester phosphodiesterase
HEHGKEEJ_00239 1.24e-280 aspC - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEHGKEEJ_00240 5.03e-166 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HEHGKEEJ_00241 1.52e-200 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HEHGKEEJ_00242 8.74e-299 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HEHGKEEJ_00243 7.81e-42 - - - S - - - Protein of unknown function (DUF2929)
HEHGKEEJ_00244 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HEHGKEEJ_00245 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HEHGKEEJ_00246 2.27e-216 yitL - - S ko:K00243 - ko00000 S1 domain
HEHGKEEJ_00247 4.23e-214 xerD - - D ko:K04763 - ko00000,ko03036 recombinase XerD
HEHGKEEJ_00248 3.67e-86 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HEHGKEEJ_00249 2.37e-178 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HEHGKEEJ_00250 1.57e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HEHGKEEJ_00251 1.18e-163 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HEHGKEEJ_00252 1.12e-149 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEHGKEEJ_00253 2.36e-216 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation
HEHGKEEJ_00254 6.9e-134 dnaQ 2.7.7.7 - L ko:K02342 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEHGKEEJ_00255 6.13e-100 XK27_04775 - - S ko:K09155 - ko00000 PAS domain
HEHGKEEJ_00256 2.63e-115 - - - K - - - Acetyltransferase (GNAT) domain
HEHGKEEJ_00257 1.2e-105 ydiB - - O ko:K06925 - ko00000,ko03016 Hydrolase, P-loop family
HEHGKEEJ_00258 1.38e-228 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 phosphate acetyltransferase
HEHGKEEJ_00259 1.84e-174 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HEHGKEEJ_00260 9.61e-137 - - - - - - - -
HEHGKEEJ_00261 7.73e-109 smpB - - J ko:K03664 - ko00000 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HEHGKEEJ_00262 0.0 rnr - - J ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HEHGKEEJ_00263 6.17e-192 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Serine aminopeptidase, S33
HEHGKEEJ_00264 1.43e-47 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HEHGKEEJ_00265 0.0 eriC - - P ko:K03281 - ko00000 chloride
HEHGKEEJ_00266 0.0 yifK - - E ko:K03293 - ko00000 Amino acid permease
HEHGKEEJ_00267 1.06e-100 cylB - - V ko:K11051 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 type transporter
HEHGKEEJ_00268 4.34e-200 - - - V ko:K11050 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEHGKEEJ_00269 2.48e-58 - - - - - - - -
HEHGKEEJ_00270 3.48e-121 - - - L - - - PFAM Integrase catalytic region
HEHGKEEJ_00271 6.12e-71 - - - L - - - PFAM Integrase catalytic region
HEHGKEEJ_00272 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 E1-E2 ATPase
HEHGKEEJ_00273 1.35e-46 - - - C - - - Heavy-metal-associated domain
HEHGKEEJ_00274 2.13e-122 dpsB - - P - - - Belongs to the Dps family
HEHGKEEJ_00275 3.39e-146 fnr - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HEHGKEEJ_00276 4.84e-21 ung2 - - L - - - Uracil-DNA glycosylase
HEHGKEEJ_00277 4.43e-13 - - - L - - - Winged helix-turn helix
HEHGKEEJ_00279 3.62e-268 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HEHGKEEJ_00280 0.0 - 1.8.1.7 - C ko:K00383 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 pyridine nucleotide-disulfide oxidoreductase
HEHGKEEJ_00281 2.89e-110 yvbK - - K - - - GNAT family
HEHGKEEJ_00282 5.22e-120 - - - - - - - -
HEHGKEEJ_00283 7.82e-161 pnb - - C - - - nitroreductase
HEHGKEEJ_00284 1.77e-107 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Methyltransferase
HEHGKEEJ_00285 1.42e-126 thrB 2.7.1.39 - F ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HEHGKEEJ_00286 5.13e-219 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HEHGKEEJ_00287 8.37e-231 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Threonine synthase
HEHGKEEJ_00288 3.06e-28 rhaS4 - - K - - - helix_turn_helix, arabinose operon control protein
HEHGKEEJ_00289 6.88e-170 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Belongs to the alpha-acetolactate decarboxylase family
HEHGKEEJ_00290 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HEHGKEEJ_00291 0.0 fhs 6.3.4.3 - F ko:K01938 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Belongs to the formate--tetrahydrofolate ligase family
HEHGKEEJ_00292 3.86e-223 ydbI - - K - - - AI-2E family transporter
HEHGKEEJ_00293 7.79e-290 cfa 2.1.1.79 - M ko:K00574 - ko00000,ko01000 cyclopropane-fatty-acyl-phospholipid synthase
HEHGKEEJ_00294 2.62e-122 ribB 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HEHGKEEJ_00295 5.59e-54 - - - H - - - RibD C-terminal domain
HEHGKEEJ_00296 1.15e-26 - - - S - - - PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEHGKEEJ_00297 3.43e-27 - - - L - - - Addiction module antitoxin, RelB DinJ family
HEHGKEEJ_00298 6.53e-118 - - - J ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HEHGKEEJ_00299 9.8e-75 - - - S - - - Antibiotic biosynthesis monooxygenase
HEHGKEEJ_00300 5.85e-254 flp - - V - - - Beta-lactamase
HEHGKEEJ_00301 2.6e-124 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEHGKEEJ_00302 2.81e-158 - - - S ko:K07507 - ko00000,ko02000 MgtC family
HEHGKEEJ_00303 4.91e-156 - - - S - - - GyrI-like small molecule binding domain
HEHGKEEJ_00305 3.18e-160 - - - S - - - Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HEHGKEEJ_00306 1.52e-64 azlD - - E - - - Branched-chain amino acid transport
HEHGKEEJ_00307 4.61e-155 azlC - - E - - - azaleucine resistance protein AzlC
HEHGKEEJ_00308 0.0 - - - K - - - Aminotransferase class I and II
HEHGKEEJ_00309 0.0 - - - S - - - amidohydrolase
HEHGKEEJ_00310 1.86e-212 - - - S - - - reductase
HEHGKEEJ_00311 2.55e-120 - 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase, GNAT family
HEHGKEEJ_00312 4.28e-177 jag - - S ko:K06346 - ko00000 R3H domain protein
HEHGKEEJ_00313 2.96e-172 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEHGKEEJ_00314 9.81e-77 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HEHGKEEJ_00315 7.96e-21 rpmH - - J ko:K02914 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL34 family
HEHGKEEJ_00316 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HEHGKEEJ_00317 1.21e-264 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HEHGKEEJ_00318 5.41e-47 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain protein YaaA
HEHGKEEJ_00319 2.07e-262 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HEHGKEEJ_00320 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEHGKEEJ_00321 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HEHGKEEJ_00322 4.55e-64 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HEHGKEEJ_00323 4e-112 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HEHGKEEJ_00324 9.36e-48 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HEHGKEEJ_00325 1.45e-85 - - - K - - - Transcriptional regulator, GntR family
HEHGKEEJ_00326 1.24e-199 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_00327 1.66e-147 - - - - - - - -
HEHGKEEJ_00328 4.51e-181 - - - G - - - MucBP domain
HEHGKEEJ_00329 7.74e-131 - - - S - - - Pfam:DUF3816
HEHGKEEJ_00330 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HEHGKEEJ_00331 3.96e-37 - - - - - - - -
HEHGKEEJ_00332 3.69e-54 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPR
HEHGKEEJ_00333 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEHGKEEJ_00334 1.88e-292 pimB 2.4.1.337 GT4 M ko:K19002 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HEHGKEEJ_00335 4.82e-254 cpoA 2.4.1.208 GT4 M ko:K13677,ko:K13678 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Glycosyltransferase, group 1 family protein
HEHGKEEJ_00336 1.8e-226 mprF - - I ko:K07027 - ko00000,ko02000 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEHGKEEJ_00337 5.67e-53 - - - S - - - Protein of unknown function (DUF1797)
HEHGKEEJ_00338 7.58e-63 ywnA - - K - - - Transcriptional regulator
HEHGKEEJ_00339 0.0 pepN 3.4.11.2 - E ko:K01256 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 aminopeptidase
HEHGKEEJ_00340 8.37e-145 - - - GM - - - NAD dependent epimerase dehydratase family protein
HEHGKEEJ_00341 0.0 pepE 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 aminopeptidase
HEHGKEEJ_00342 2.65e-269 - - - EGP - - - Major Facilitator Superfamily
HEHGKEEJ_00343 2.05e-294 - - - - - - - -
HEHGKEEJ_00344 1.85e-108 - - - K - - - Transcriptional regulator, HxlR family
HEHGKEEJ_00345 1.41e-141 XK27_02070 - - S ko:K07078 - ko00000 Nitroreductase family
HEHGKEEJ_00346 2.74e-69 ydeP - - K - - - Transcriptional regulator, HxlR family
HEHGKEEJ_00347 6.67e-158 - - - GM - - - NmrA-like family
HEHGKEEJ_00348 7.65e-101 - - - S ko:K02348 - ko00000 Gnat family
HEHGKEEJ_00349 2.3e-52 - - - S - - - Cytochrome B5
HEHGKEEJ_00350 8.47e-08 - - - S - - - Cytochrome B5
HEHGKEEJ_00351 5.47e-55 - - - S - - - Cytochrome B5
HEHGKEEJ_00352 4.3e-169 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HEHGKEEJ_00353 4.5e-50 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEHGKEEJ_00354 1.98e-163 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEHGKEEJ_00355 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HEHGKEEJ_00356 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HEHGKEEJ_00357 3.24e-249 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HEHGKEEJ_00358 2.37e-135 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HEHGKEEJ_00359 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HEHGKEEJ_00360 7.07e-311 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HEHGKEEJ_00361 5.27e-169 gpmA 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEHGKEEJ_00362 2.88e-229 - - - - - - - -
HEHGKEEJ_00363 5.09e-162 - - - M - - - ErfK YbiS YcfS YnhG
HEHGKEEJ_00365 5.74e-62 - - - - - - - -
HEHGKEEJ_00366 1.02e-279 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEHGKEEJ_00367 1.48e-187 - - - S - - - Alpha beta hydrolase
HEHGKEEJ_00368 5.74e-264 gldA 1.1.1.6 - C ko:K00005 ko00561,ko00640,ko01100,map00561,map00640,map01100 ko00000,ko00001,ko01000 dehydrogenase
HEHGKEEJ_00369 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEHGKEEJ_00370 1.77e-56 - - - - - - - -
HEHGKEEJ_00371 9.13e-160 pgm3 - - G - - - phosphoglycerate mutase family
HEHGKEEJ_00372 0.0 - - - S - - - C4-dicarboxylate anaerobic carrier
HEHGKEEJ_00373 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEHGKEEJ_00374 1.29e-149 dedA - - S ko:K03975 - ko00000 SNARE-like domain protein
HEHGKEEJ_00375 7.15e-148 - - - S - - - Protein of unknown function (DUF1461)
HEHGKEEJ_00376 1.44e-180 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HEHGKEEJ_00377 3.03e-129 yutD - - S - - - Protein of unknown function (DUF1027)
HEHGKEEJ_00378 6.01e-153 - - - S - - - Calcineurin-like phosphoesterase
HEHGKEEJ_00379 1.36e-286 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HEHGKEEJ_00380 5.09e-186 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 N-6 DNA Methylase
HEHGKEEJ_00382 1.01e-95 - - - - ko:K02248 - ko00000,ko00002,ko02044 -
HEHGKEEJ_00383 3.65e-60 - - - - - - - -
HEHGKEEJ_00384 3.65e-103 - - - NU ko:K02246 - ko00000,ko00002,ko02044 general secretion pathway protein
HEHGKEEJ_00385 6.31e-62 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 competence protein ComGC
HEHGKEEJ_00386 2.95e-240 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 type II secretion system
HEHGKEEJ_00387 8.77e-237 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 Type II IV secretion system protein
HEHGKEEJ_00388 1.22e-168 yebC - - K - - - Transcriptional regulatory protein
HEHGKEEJ_00389 1.47e-181 - - - - - - - -
HEHGKEEJ_00390 1.7e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HEHGKEEJ_00391 6.25e-272 pepQ 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEHGKEEJ_00392 2.93e-58 - - - - - - - -
HEHGKEEJ_00393 1.54e-71 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HEHGKEEJ_00394 1.6e-190 ykuT - - M ko:K16052,ko:K22044 - ko00000,ko02000 mechanosensitive ion channel
HEHGKEEJ_00395 1.15e-197 - - - S - - - haloacid dehalogenase-like hydrolase
HEHGKEEJ_00396 1.79e-100 ykuL - - S - - - (CBS) domain
HEHGKEEJ_00397 1.16e-124 - - - S ko:K07095 - ko00000 Phosphoesterase
HEHGKEEJ_00398 5.35e-139 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HEHGKEEJ_00399 3.41e-189 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HEHGKEEJ_00400 3.01e-126 yslB - - S - - - Protein of unknown function (DUF2507)
HEHGKEEJ_00401 2.86e-72 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEHGKEEJ_00402 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HEHGKEEJ_00403 7.15e-122 cvpA - - S - - - Colicin V production protein
HEHGKEEJ_00404 3.75e-63 yrzB - - S - - - Belongs to the UPF0473 family
HEHGKEEJ_00405 3.62e-100 yrrK - - J ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HEHGKEEJ_00406 8.03e-58 yrzL - - S - - - Belongs to the UPF0297 family
HEHGKEEJ_00407 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HEHGKEEJ_00408 0.0 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HEHGKEEJ_00409 2.15e-234 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 DHHA1 domain protein
HEHGKEEJ_00410 1.86e-62 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase
HEHGKEEJ_00411 1.11e-260 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HEHGKEEJ_00412 9.97e-245 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HEHGKEEJ_00413 4.52e-133 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HEHGKEEJ_00414 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HEHGKEEJ_00415 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HEHGKEEJ_00416 3.26e-276 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HEHGKEEJ_00417 7.67e-252 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HEHGKEEJ_00418 1.28e-295 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HEHGKEEJ_00419 1.16e-133 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HEHGKEEJ_00420 1.45e-197 - - - S - - - Helix-turn-helix domain
HEHGKEEJ_00421 0.0 ymfH - - S - - - Peptidase M16
HEHGKEEJ_00422 3.68e-295 ymfF - - S - - - Peptidase M16 inactive domain protein
HEHGKEEJ_00423 2.84e-205 aatB - - ET ko:K02030 - ko00000,ko00002,ko02000 ABC transporter substrate-binding protein
HEHGKEEJ_00424 1.45e-151 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_00425 3.13e-141 yecS_2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_00426 1.69e-120 mreD - - M ko:K03571 - ko00000,ko03036 rod shape-determining protein MreD
HEHGKEEJ_00427 7.72e-195 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HEHGKEEJ_00428 8.33e-230 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 cell shape determining protein MreB
HEHGKEEJ_00429 5.97e-157 radC - - L ko:K03630 - ko00000 DNA repair protein
HEHGKEEJ_00430 1.9e-316 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEHGKEEJ_00431 1.09e-295 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HEHGKEEJ_00432 0.0 cydD - - CO ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HEHGKEEJ_00433 0.0 cydC - - CO ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HEHGKEEJ_00434 3.43e-236 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase subunit II
HEHGKEEJ_00435 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 ubiquinol oxidase
HEHGKEEJ_00436 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HEHGKEEJ_00437 4.1e-292 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HEHGKEEJ_00438 2.59e-276 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class V
HEHGKEEJ_00439 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HEHGKEEJ_00440 5.96e-139 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HEHGKEEJ_00441 6.84e-167 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 Universal bacterial protein YeaZ
HEHGKEEJ_00442 3.02e-135 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 Ribosomal-protein-alanine acetyltransferase
HEHGKEEJ_00443 1.74e-252 tsaD 2.3.1.234 - J ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HEHGKEEJ_00444 1.54e-171 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEHGKEEJ_00445 3.8e-292 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HEHGKEEJ_00446 2.29e-180 proB 2.7.2.11 - F ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HEHGKEEJ_00447 3.05e-189 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Carbon-nitrogen hydrolase
HEHGKEEJ_00448 1.37e-292 mtnE - - E ko:K08969 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEHGKEEJ_00449 5.28e-236 ykpB 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEHGKEEJ_00450 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter, ATP-binding protein
HEHGKEEJ_00451 4.67e-147 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HEHGKEEJ_00452 2.21e-155 XK27_07085 - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEHGKEEJ_00453 1.52e-43 - - - - - - - -
HEHGKEEJ_00454 8.45e-210 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HEHGKEEJ_00455 2.63e-240 rbsR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding proteins and sugar binding domain of LacI family
HEHGKEEJ_00456 5.33e-147 - - - - - - - -
HEHGKEEJ_00457 3.06e-150 dgk2 - - F - - - deoxynucleoside kinase
HEHGKEEJ_00458 9.46e-242 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEHGKEEJ_00459 4.4e-112 - - - T - - - Belongs to the universal stress protein A family
HEHGKEEJ_00460 0.0 pepV 3.5.1.18 - E ko:K01270,ko:K01274,ko:K01439 ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 dipeptidase PepV
HEHGKEEJ_00461 9.07e-199 nnrD 4.2.1.136, 5.1.99.6 - H ko:K17758,ko:K17759 - ko00000,ko01000 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HEHGKEEJ_00462 0.0 ytgP - - S ko:K03328 - ko00000 Polysaccharide biosynthesis protein
HEHGKEEJ_00463 1.49e-224 hepT 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEHGKEEJ_00464 6.63e-203 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 1,4-dihydroxy-2-naphthoate
HEHGKEEJ_00465 4.96e-152 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HEHGKEEJ_00466 5.6e-70 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HEHGKEEJ_00467 5.88e-164 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HEHGKEEJ_00468 3.65e-291 mdtG2 - - EGP ko:K08161 - ko00000,ko02000 Transporter, major facilitator family protein
HEHGKEEJ_00469 8.23e-214 prpA3 3.1.3.16 - T ko:K01090 - ko00000,ko01000 Calcineurin-like phosphoesterase superfamily domain
HEHGKEEJ_00470 2.48e-57 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEHGKEEJ_00471 1.49e-69 - - - L ko:K07491 - ko00000 Transposase IS200 like
HEHGKEEJ_00472 9.32e-231 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HEHGKEEJ_00475 0.0 - - - M - - - domain protein
HEHGKEEJ_00476 2.51e-83 - - - - - - - -
HEHGKEEJ_00477 3e-251 ampC - - V - - - Beta-lactamase
HEHGKEEJ_00478 1.25e-304 arcA 3.5.3.6 - E ko:K01478 ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130 ko00000,ko00001,ko01000 Arginine
HEHGKEEJ_00479 6.17e-104 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEHGKEEJ_00480 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HEHGKEEJ_00481 3.56e-300 potE - - U ko:K03756,ko:K03758 - ko00000,ko02000 Amino acid permease
HEHGKEEJ_00482 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEHGKEEJ_00483 7.66e-255 - - - EGP - - - Major Facilitator
HEHGKEEJ_00484 8.53e-120 ymdB - - S - - - Macro domain protein
HEHGKEEJ_00485 1.03e-146 - - - K - - - Helix-turn-helix XRE-family like proteins
HEHGKEEJ_00486 0.0 pepO - - O ko:K07386 - ko00000,ko01000,ko01002 Peptidase family M13
HEHGKEEJ_00487 1.48e-64 - - - - - - - -
HEHGKEEJ_00488 2.59e-314 - - - S - - - Putative metallopeptidase domain
HEHGKEEJ_00489 3.49e-269 - - - S - - - associated with various cellular activities
HEHGKEEJ_00490 8.15e-155 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HEHGKEEJ_00491 1.92e-86 yeaO - - S - - - Protein of unknown function, DUF488
HEHGKEEJ_00511 1.31e-103 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HEHGKEEJ_00512 4.08e-88 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HEHGKEEJ_00513 5.67e-157 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HEHGKEEJ_00514 3.9e-40 coiA - - S ko:K06198 - ko00000 Competence protein
HEHGKEEJ_00515 1.25e-142 coiA - - S ko:K06198 - ko00000 Competence protein
HEHGKEEJ_00516 0.0 pepDA - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEHGKEEJ_00517 2.51e-150 yjbH - - Q - - - Thioredoxin
HEHGKEEJ_00518 9.06e-151 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 RelA SpoT domain protein
HEHGKEEJ_00519 1.52e-198 nadK 2.7.1.23 - F ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HEHGKEEJ_00520 4.28e-225 yjbO 5.4.99.23 - G ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEHGKEEJ_00521 8.74e-57 - - - - - - - -
HEHGKEEJ_00522 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HEHGKEEJ_00523 6.66e-281 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HEHGKEEJ_00524 4.49e-130 tag1 3.2.2.20 - L ko:K01246 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 glycosylase
HEHGKEEJ_00525 7.96e-41 - - - - - - - -
HEHGKEEJ_00526 0.0 - - - EGP - - - Major Facilitator
HEHGKEEJ_00527 1.25e-111 perR - - P ko:K03711,ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HEHGKEEJ_00528 8.53e-304 cycA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEHGKEEJ_00529 2.01e-134 - - - V - - - VanZ like family
HEHGKEEJ_00530 7.03e-33 - - - - - - - -
HEHGKEEJ_00531 0.0 - - - L - - - PLD-like domain
HEHGKEEJ_00532 1e-61 - - - K - - - Acetyltransferase (GNAT) family
HEHGKEEJ_00533 2.64e-244 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEHGKEEJ_00534 1.12e-49 - - - IQ - - - dehydrogenase reductase
HEHGKEEJ_00542 6.11e-68 - - - - - - - -
HEHGKEEJ_00543 2.03e-182 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HEHGKEEJ_00544 3e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEHGKEEJ_00545 8.1e-153 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HEHGKEEJ_00546 6.12e-296 - - - P - - - Chloride transporter, ClC family
HEHGKEEJ_00547 0.0 agl 3.2.1.20 GH31 G ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 31 family
HEHGKEEJ_00548 5.8e-149 - - - I - - - Acid phosphatase homologues
HEHGKEEJ_00549 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEHGKEEJ_00550 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, catalytic domain protein
HEHGKEEJ_00551 0.0 - - - M - - - domain protein
HEHGKEEJ_00552 0.0 - 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Poly(Glycerol-phosphate) alpha-glucosyltransferase
HEHGKEEJ_00553 0.0 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HEHGKEEJ_00554 8.53e-95 - - - - - - - -
HEHGKEEJ_00555 9.17e-59 - - - - - - - -
HEHGKEEJ_00557 1.72e-130 int3 - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_00561 8.89e-22 - - - - - - - -
HEHGKEEJ_00563 1.28e-54 - - - K - - - Helix-turn-helix domain
HEHGKEEJ_00564 0.00077 - - - K - - - Helix-turn-helix XRE-family like proteins
HEHGKEEJ_00565 3.94e-120 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HEHGKEEJ_00566 1.97e-31 - - - S - - - Domain of unknown function (DUF771)
HEHGKEEJ_00573 9.99e-17 - - - K - - - ParB-like nuclease domain
HEHGKEEJ_00575 1.01e-202 - - - L ko:K07455 - ko00000,ko03400 RecT family
HEHGKEEJ_00576 3.89e-203 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
HEHGKEEJ_00577 1.29e-05 - - - L - - - HNH nucleases
HEHGKEEJ_00578 1.75e-110 - - - L - - - Psort location Cytoplasmic, score
HEHGKEEJ_00579 6.35e-76 - - - - - - - -
HEHGKEEJ_00581 2.25e-52 - - - S - - - ORF6C domain
HEHGKEEJ_00583 5.37e-35 - - - - - - - -
HEHGKEEJ_00584 5.82e-12 - - - - - - - -
HEHGKEEJ_00587 1.65e-31 - - - - - - - -
HEHGKEEJ_00589 3.16e-158 - 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 sulfate reduction
HEHGKEEJ_00591 1.24e-131 - - - K - - - Belongs to the N(4) N(6)-methyltransferase family
HEHGKEEJ_00594 1.87e-89 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HEHGKEEJ_00595 8.35e-16 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HEHGKEEJ_00597 5.89e-197 - - - S ko:K06909 - ko00000 Phage terminase, large subunit
HEHGKEEJ_00598 0.0 - - - S - - - Phage portal protein, SPP1 Gp6-like
HEHGKEEJ_00599 2.04e-226 - - - S - - - Phage Mu protein F like protein
HEHGKEEJ_00601 5.53e-109 - - - S - - - Domain of unknown function (DUF4355)
HEHGKEEJ_00602 1.18e-253 gpG - - - - - - -
HEHGKEEJ_00603 1.37e-78 - - - S - - - Phage gp6-like head-tail connector protein
HEHGKEEJ_00604 6.51e-69 - - - - - - - -
HEHGKEEJ_00605 5.35e-121 - - - - - - - -
HEHGKEEJ_00606 1.52e-89 - - - - - - - -
HEHGKEEJ_00607 9.27e-151 - - - - - - - -
HEHGKEEJ_00608 1.08e-113 - - - S - - - Phage tail assembly chaperone protein, TAC
HEHGKEEJ_00609 0.0 - - - D - - - domain protein
HEHGKEEJ_00610 1.86e-121 - - - S - - - Phage tail protein
HEHGKEEJ_00611 2.19e-241 - - - S - - - Peptidase family M23
HEHGKEEJ_00614 1.49e-46 - - - S - - - Calcineurin-like phosphoesterase
HEHGKEEJ_00615 2.1e-05 - - - N - - - Bacterial Ig-like domain 2
HEHGKEEJ_00621 7.45e-44 - - - - - - - -
HEHGKEEJ_00622 1.05e-64 - - - S - - - Bacteriophage holin of superfamily 6 (Holin_LLH)
HEHGKEEJ_00623 5.73e-195 - - - M - - - Glycosyl hydrolases family 25
HEHGKEEJ_00624 8.92e-16 - - - T - - - SpoVT / AbrB like domain
HEHGKEEJ_00625 2.08e-30 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEHGKEEJ_00626 5.82e-96 - - - - - - - -
HEHGKEEJ_00627 1.22e-74 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HEHGKEEJ_00628 4.05e-124 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HEHGKEEJ_00629 9.63e-136 folE 2.7.6.3, 3.5.4.16 - F ko:K00950,ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase 1
HEHGKEEJ_00630 5.72e-301 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HEHGKEEJ_00631 8.88e-138 folQ 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Ham1 family
HEHGKEEJ_00632 5.66e-278 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 dihydropteroate synthase
HEHGKEEJ_00633 4.61e-61 - - - - - - - -
HEHGKEEJ_00634 1.49e-54 - - - - - - - -
HEHGKEEJ_00636 2.84e-52 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEHGKEEJ_00637 1.47e-153 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEHGKEEJ_00638 6.15e-194 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HEHGKEEJ_00639 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HEHGKEEJ_00640 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HEHGKEEJ_00641 3.9e-79 yheA - - S - - - Belongs to the UPF0342 family
HEHGKEEJ_00642 3.37e-294 yhaO - - L ko:K03547 - ko00000,ko03400 Ser Thr phosphatase family protein
HEHGKEEJ_00643 0.0 yhaN - - L - - - AAA domain
HEHGKEEJ_00644 5.8e-176 prsA 5.2.1.8 - M ko:K07533 - ko00000,ko01000,ko03110 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HEHGKEEJ_00646 1.49e-102 hit - - FG ko:K02503 - ko00000,ko04147 histidine triad
HEHGKEEJ_00647 1.39e-177 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_00648 3.44e-281 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HEHGKEEJ_00649 4.53e-158 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HEHGKEEJ_00650 2.82e-34 - - - S - - - YSIRK type signal peptide
HEHGKEEJ_00651 3.3e-174 - - - S - - - YSIRK type signal peptide
HEHGKEEJ_00652 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HEHGKEEJ_00653 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HEHGKEEJ_00654 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HEHGKEEJ_00655 0.0 murE 6.3.2.13, 6.3.2.7 - M ko:K01928,ko:K05362 ko00300,ko00550,ko01100,map00300,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HEHGKEEJ_00656 1.81e-315 yxbA 6.3.1.12 - S ko:K17810 - ko00000,ko01000 ATP-grasp enzyme
HEHGKEEJ_00657 6.09e-69 - - - M - - - Peptidase_C39 like family
HEHGKEEJ_00658 2.73e-21 - - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 NLP P60 protein
HEHGKEEJ_00659 0.0 prfC - - J ko:K02837 - ko00000,ko03012 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HEHGKEEJ_00660 1.32e-23 - - - - - - - -
HEHGKEEJ_00661 4.55e-118 - - - M - - - Glycosyl transferase family 2
HEHGKEEJ_00662 9.77e-293 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEHGKEEJ_00663 1.43e-252 galM 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of alpha and beta anomers of maltose
HEHGKEEJ_00664 6.92e-31 - - - - - - - -
HEHGKEEJ_00665 0.0 - - - S ko:K13730 ko05100,map05100 ko00000,ko00001 Uncharacterized protein conserved in bacteria (DUF2252)
HEHGKEEJ_00666 8.63e-213 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HEHGKEEJ_00667 0.0 - - - L - - - PFAM plasmid pRiA4b ORF-3 family protein
HEHGKEEJ_00668 1.15e-264 adh 1.1.1.1 - C ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Zinc-binding alcohol dehydrogenase family protein
HEHGKEEJ_00669 8.22e-144 ppiB 5.2.1.8 - G ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HEHGKEEJ_00670 2.07e-236 cytR - - K ko:K02529,ko:K03604 - ko00000,ko03000 Transcriptional regulator, LacI family
HEHGKEEJ_00671 0.0 - - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEHGKEEJ_00672 3.22e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HEHGKEEJ_00673 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEHGKEEJ_00674 5.67e-313 XK27_08635 - - S ko:K09157 - ko00000 UPF0210 protein
HEHGKEEJ_00675 1.02e-51 XK27_08630 - - T ko:K07166 - ko00000 Belongs to the UPF0237 family
HEHGKEEJ_00676 1.08e-221 yvgN - - C - - - Aldo keto reductase
HEHGKEEJ_00677 2.08e-208 rlrB - - K - - - LysR substrate binding domain protein
HEHGKEEJ_00678 7.72e-114 - - - C - - - Flavodoxin
HEHGKEEJ_00679 9.07e-106 - - - S - - - Cupin domain
HEHGKEEJ_00680 1.35e-97 - - - S - - - UPF0756 membrane protein
HEHGKEEJ_00681 5.84e-309 - - - U - - - Belongs to the major facilitator superfamily
HEHGKEEJ_00682 1.68e-98 atkY - - K ko:K02171 ko01501,map01501 ko00000,ko00001,ko00002,ko01504,ko03000 Copper transport repressor CopY TcrY
HEHGKEEJ_00683 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HEHGKEEJ_00684 1.25e-97 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEHGKEEJ_00685 3.65e-308 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HEHGKEEJ_00686 6.51e-270 yttB - - EGP - - - Major Facilitator
HEHGKEEJ_00687 1.56e-80 - - - - - - - -
HEHGKEEJ_00688 1.36e-212 - - - S - - - Polyphosphate nucleotide phosphotransferase, PPK2 family
HEHGKEEJ_00689 3.7e-11 - - - K - - - Helix-turn-helix XRE-family like proteins
HEHGKEEJ_00690 1.54e-05 - - - K - - - Helix-turn-helix XRE-family like proteins
HEHGKEEJ_00691 3.01e-63 int2 - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_00693 1.94e-64 - - - S - - - Lipopolysaccharide assembly protein A domain
HEHGKEEJ_00694 3.73e-203 - 3.1.3.102, 3.1.3.104 - S ko:K20861 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HEHGKEEJ_00695 1.38e-117 ntd 2.4.2.6 - F ko:K08728 ko00240,map00240 ko00000,ko00001,ko01000 Nucleoside
HEHGKEEJ_00696 5.02e-29 - - - - - - - -
HEHGKEEJ_00697 5.57e-214 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEHGKEEJ_00698 3.57e-150 - - - S - - - Protein of unknown function (DUF421)
HEHGKEEJ_00699 2.7e-39 - - - S - - - Protein of unknown function (DUF3290)
HEHGKEEJ_00700 5.07e-39 - - - S - - - Protein of unknown function (DUF3290)
HEHGKEEJ_00701 7.11e-57 - - - S ko:K09790 - ko00000 Protein of unknown function (DUF454)
HEHGKEEJ_00702 1.24e-83 - - - C - - - Flavodoxin
HEHGKEEJ_00703 1.15e-15 - 1.1.1.346 - S ko:K06221 - ko00000,ko01000 Oxidoreductase, aldo keto reductase family protein
HEHGKEEJ_00704 2e-73 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 decarboxylase
HEHGKEEJ_00705 6.2e-155 - - - M - - - Protein of unknown function (DUF3737)
HEHGKEEJ_00706 5.77e-291 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase, class I
HEHGKEEJ_00707 5.46e-207 - - - S ko:K07088 - ko00000 Membrane transport protein
HEHGKEEJ_00708 2.58e-154 - - - H - - - RibD C-terminal domain
HEHGKEEJ_00713 3.66e-102 endA - - F ko:K15051 - ko00000 DNA RNA non-specific endonuclease
HEHGKEEJ_00715 7.4e-28 - - - M - - - MucBP domain
HEHGKEEJ_00717 6.92e-184 uppS 2.5.1.31 - H ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HEHGKEEJ_00718 2.03e-178 cdsA 2.7.7.41 - I ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HEHGKEEJ_00719 9.87e-300 rseP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HEHGKEEJ_00720 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HEHGKEEJ_00721 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEHGKEEJ_00722 1.1e-108 rimP - - J ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HEHGKEEJ_00723 3.54e-276 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HEHGKEEJ_00724 5.93e-60 ylxR - - K ko:K07742 - ko00000 Protein of unknown function (DUF448)
HEHGKEEJ_00725 1.96e-65 ylxQ - - J - - - ribosomal protein
HEHGKEEJ_00726 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HEHGKEEJ_00727 1.38e-77 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HEHGKEEJ_00728 1.48e-216 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HEHGKEEJ_00729 4.14e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HEHGKEEJ_00730 3.09e-85 - - - - - - - -
HEHGKEEJ_00731 1.37e-248 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HEHGKEEJ_00732 2.83e-118 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HEHGKEEJ_00733 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HEHGKEEJ_00734 3.81e-274 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HEHGKEEJ_00735 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HEHGKEEJ_00736 4.55e-288 int7 - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_00737 1.7e-182 - - - - - - - -
HEHGKEEJ_00738 4.29e-18 - - - - - - - -
HEHGKEEJ_00739 2.44e-99 - - - - - - - -
HEHGKEEJ_00740 1.71e-105 - - - - - - - -
HEHGKEEJ_00741 2.6e-14 - - - K - - - Peptidase S24-like
HEHGKEEJ_00742 1.21e-30 - - - K - - - Peptidase S24-like
HEHGKEEJ_00743 0.0 pepD3 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEHGKEEJ_00744 3.16e-258 - - - C - - - Belongs to the LDH2 MDH2 oxidoreductase family
HEHGKEEJ_00745 3.37e-222 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEHGKEEJ_00747 3.36e-77 - - - - - - - -
HEHGKEEJ_00748 2.15e-234 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Ribosomal protein L11 methyltransferase
HEHGKEEJ_00749 1.05e-168 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HEHGKEEJ_00750 2.38e-72 - - - - - - - -
HEHGKEEJ_00751 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HEHGKEEJ_00752 2.19e-100 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HEHGKEEJ_00753 2.65e-214 - - - G - - - Phosphotransferase enzyme family
HEHGKEEJ_00754 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HEHGKEEJ_00755 1.89e-171 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_00756 0.0 glnPH2 - - P ko:K02029,ko:K02030 - ko00000,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_00757 1e-31 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HEHGKEEJ_00758 1.58e-90 yqeY - - S ko:K09117 - ko00000 YqeY-like protein
HEHGKEEJ_00759 9.82e-234 cbh 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HEHGKEEJ_00760 1.46e-303 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HEHGKEEJ_00761 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HEHGKEEJ_00762 4.64e-35 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEHGKEEJ_00763 3.22e-75 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HEHGKEEJ_00764 1.23e-226 birA 6.3.4.15 - H ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HEHGKEEJ_00765 6.39e-235 phoH - - T ko:K06217 - ko00000 phosphate starvation-inducible protein PhoH
HEHGKEEJ_00766 1.55e-109 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HEHGKEEJ_00767 1.8e-81 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HEHGKEEJ_00768 2.66e-219 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HEHGKEEJ_00769 1.24e-188 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HEHGKEEJ_00770 2.5e-233 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HEHGKEEJ_00771 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HEHGKEEJ_00772 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HEHGKEEJ_00773 5.12e-266 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HEHGKEEJ_00774 7.69e-100 - - - - - - - -
HEHGKEEJ_00775 2.4e-231 - - - - - - - -
HEHGKEEJ_00776 3.84e-60 - - - L - - - transposase and inactivated derivatives, IS30 family
HEHGKEEJ_00777 5.09e-162 - - - L - - - PFAM Integrase catalytic region
HEHGKEEJ_00778 5.32e-06 - - - - - - - -
HEHGKEEJ_00779 3.45e-49 - - - L - - - Transposase and inactivated derivatives, IS30 family
HEHGKEEJ_00780 2.71e-315 tnp2 - - L - - - Transposase
HEHGKEEJ_00781 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HEHGKEEJ_00782 1.16e-238 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HEHGKEEJ_00783 1.94e-257 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HEHGKEEJ_00784 1.84e-152 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Acyltransferase
HEHGKEEJ_00785 2.92e-182 yabB 2.1.1.223 - L ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
HEHGKEEJ_00786 6.79e-65 yazA - - L ko:K07461 - ko00000 GIY-YIG catalytic domain protein
HEHGKEEJ_00787 8.74e-235 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEHGKEEJ_00788 3.54e-184 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HEHGKEEJ_00789 3.14e-197 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HEHGKEEJ_00790 2.21e-167 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HEHGKEEJ_00791 7.32e-124 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HEHGKEEJ_00792 0.0 lacZ 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 -beta-galactosidase
HEHGKEEJ_00793 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HEHGKEEJ_00794 9.5e-239 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEHGKEEJ_00795 1.81e-108 - - - - - - - -
HEHGKEEJ_00796 0.0 gshAB 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HEHGKEEJ_00797 1.2e-268 - - - P - - - Voltage gated chloride channel
HEHGKEEJ_00798 4.59e-289 sptS - - T - - - Histidine kinase
HEHGKEEJ_00799 1.1e-153 dltr - - K - - - response regulator
HEHGKEEJ_00800 2.92e-111 - - - T - - - Region found in RelA / SpoT proteins
HEHGKEEJ_00801 2.46e-93 - - - - - - - -
HEHGKEEJ_00802 4.32e-155 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 beta-phosphoglucomutase
HEHGKEEJ_00803 0.0 mapA 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 hydrolase, family 65, central catalytic
HEHGKEEJ_00804 0.0 malT - - G ko:K16211 - ko00000,ko02000 Major Facilitator
HEHGKEEJ_00805 4.84e-277 atoB 1.1.1.88, 2.3.1.9 - I ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HEHGKEEJ_00806 9.34e-225 malR1 - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator, LacI family
HEHGKEEJ_00807 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HEHGKEEJ_00808 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HEHGKEEJ_00809 0.0 cls - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEHGKEEJ_00810 1.22e-139 - - - K - - - PFAM GCN5-related N-acetyltransferase
HEHGKEEJ_00812 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 associated with various cellular activities
HEHGKEEJ_00813 8.68e-44 - - - - - - - -
HEHGKEEJ_00814 2.83e-282 - - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEHGKEEJ_00815 5.24e-232 ldhD 1.1.1.28 - CH ko:K03778 ko00620,ko01120,map00620,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEHGKEEJ_00816 6.86e-98 - - - O - - - OsmC-like protein
HEHGKEEJ_00817 1.37e-35 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HEHGKEEJ_00820 0.0 - - - S - - - Putative peptidoglycan binding domain
HEHGKEEJ_00821 7.63e-64 - - - - - - - -
HEHGKEEJ_00823 3.16e-278 - - - V ko:K02004 - ko00000,ko00002,ko02000 MacB-like periplasmic core domain
HEHGKEEJ_00824 1.69e-167 - - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HEHGKEEJ_00825 1.06e-202 hlyD3 - - M ko:K02005 - ko00000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HEHGKEEJ_00826 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HEHGKEEJ_00827 2.13e-189 - 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HEHGKEEJ_00828 1.52e-192 - - - E - - - Glyoxalase-like domain
HEHGKEEJ_00829 1.39e-198 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HEHGKEEJ_00830 1.08e-288 dhaT 1.1.1.202 - C ko:K00086 ko00561,ko00640,map00561,map00640 ko00000,ko00001,ko01000 Dehydrogenase
HEHGKEEJ_00831 1.56e-125 - - - S - - - reductase
HEHGKEEJ_00833 2.63e-115 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HEHGKEEJ_00834 3.41e-231 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HEHGKEEJ_00835 5.79e-117 pgpA - - I - - - Phosphatidylglycerophosphatase A
HEHGKEEJ_00836 6.24e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 serine protease
HEHGKEEJ_00837 3.06e-197 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 domain protein
HEHGKEEJ_00838 6.38e-196 yycI - - S - - - YycH protein
HEHGKEEJ_00839 0.0 yycH - - S - - - YycH protein
HEHGKEEJ_00840 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEHGKEEJ_00841 3.69e-168 yycF - - K ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HEHGKEEJ_00843 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HEHGKEEJ_00844 6.55e-97 - - - K ko:K18909 - ko00000,ko00002,ko01504,ko03000 helix_turn_helix multiple antibiotic resistance protein
HEHGKEEJ_00848 1.99e-05 - - - D - - - nuclear chromosome segregation
HEHGKEEJ_00849 1.52e-281 - - - J - - - Elongation factor G, domain IV
HEHGKEEJ_00850 7.31e-155 - - - J - - - Elongation factor G, domain IV
HEHGKEEJ_00851 7.06e-29 - - - K - - - sequence-specific DNA binding
HEHGKEEJ_00852 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HEHGKEEJ_00853 8.39e-151 - - - S ko:K03975 - ko00000 SNARE associated Golgi protein
HEHGKEEJ_00854 5.5e-161 pgm3 - - G - - - phosphoglycerate mutase
HEHGKEEJ_00855 1.58e-301 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HEHGKEEJ_00856 1.1e-12 - - - - - - - -
HEHGKEEJ_00857 2.44e-125 - - - K - - - Acetyltransferase (GNAT) family
HEHGKEEJ_00858 2.57e-103 - - - K - - - LytTr DNA-binding domain
HEHGKEEJ_00859 4.56e-99 - - - S - - - Protein of unknown function (DUF3021)
HEHGKEEJ_00860 1.22e-218 - 3.2.1.96, 3.5.1.28 GH73 M ko:K01227,ko:K01447,ko:K13714,ko:K13731 ko00511,ko05100,map00511,map05100 ko00000,ko00001,ko01000 N-acetylmuramoyl-L-alanine amidase
HEHGKEEJ_00861 4.43e-100 XK27_00915 - - C - - - Luciferase-like monooxygenase
HEHGKEEJ_00862 1.78e-160 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HEHGKEEJ_00863 2.73e-52 - - - L - - - Helicase C-terminal domain protein
HEHGKEEJ_00864 6.5e-16 - - - - - - - -
HEHGKEEJ_00866 1.55e-217 - - - L - - - Plasmid pRiA4b ORF-3-like protein
HEHGKEEJ_00868 9.77e-80 - - - S - - - Protein of unknown function (DUF3021)
HEHGKEEJ_00869 1.46e-96 - - - K - - - LytTr DNA-binding domain
HEHGKEEJ_00870 6.18e-231 yueF - - S - - - AI-2E family transporter
HEHGKEEJ_00871 2.62e-41 - - - S ko:K21471 - ko00000,ko01000,ko01002,ko01011 dextransucrase activity
HEHGKEEJ_00874 2.4e-230 apbE 2.7.1.180 - H ko:K03734 - ko00000,ko01000 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HEHGKEEJ_00875 4.97e-273 - 1.5.1.36 - S ko:K19784,ko:K22393,ko:K22394 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HEHGKEEJ_00876 6e-132 - 1.5.1.36 - S ko:K19784,ko:K22393 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 reductase
HEHGKEEJ_00878 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEHGKEEJ_00879 0.0 - - - M - - - Rib/alpha-like repeat
HEHGKEEJ_00881 6.68e-238 - - - - - - - -
HEHGKEEJ_00882 2.75e-106 - - - K - - - acetyltransferase
HEHGKEEJ_00883 6.92e-179 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HEHGKEEJ_00884 9.3e-202 - - - K - - - LysR substrate binding domain
HEHGKEEJ_00886 7.35e-54 - - - M - - - KxYKxGKxW signal domain protein
HEHGKEEJ_00891 1.6e-40 XK26_06720 - - S ko:K09976 - ko00000 Uncharacterised protein family (UPF0154)
HEHGKEEJ_00892 2.7e-47 ynzC - - S - - - UPF0291 protein
HEHGKEEJ_00893 2.52e-148 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HEHGKEEJ_00894 1.49e-272 mvaS 2.3.3.10 - I ko:K01641 ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA synthase
HEHGKEEJ_00895 3.18e-167 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEHGKEEJ_00896 0.0 repE - - K - - - Primase C terminal 1 (PriCT-1)
HEHGKEEJ_00897 1.58e-167 soj - - D - - - CobQ CobB MinD ParA nucleotide binding domain protein
HEHGKEEJ_00899 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Asparaginyl-tRNA synthetase
HEHGKEEJ_00900 2.03e-252 asnA 6.3.1.1 - F ko:K01914 ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230 ko00000,ko00001,ko01000 aspartate--ammonia ligase
HEHGKEEJ_00901 4.39e-120 - - - S - - - ECF transporter, substrate-specific component
HEHGKEEJ_00902 4.64e-37 - - - Q - - - pyridine nucleotide-disulphide oxidoreductase
HEHGKEEJ_00903 6.71e-207 - - - EG - - - EamA-like transporter family
HEHGKEEJ_00904 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HEHGKEEJ_00905 3.97e-198 - - - EG - - - EamA-like transporter family
HEHGKEEJ_00906 1.15e-152 - - - L - - - Integrase
HEHGKEEJ_00907 3.59e-204 rssA - - S - - - Phospholipase, patatin family
HEHGKEEJ_00908 7.57e-206 - - - - - - - -
HEHGKEEJ_00909 9.91e-204 - - - G - - - Xylose isomerase domain protein TIM barrel
HEHGKEEJ_00910 2.39e-239 XK27_12525 - - S - - - AI-2E family transporter
HEHGKEEJ_00911 0.0 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HEHGKEEJ_00912 1.18e-273 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HEHGKEEJ_00913 5.18e-109 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HEHGKEEJ_00914 9.06e-60 - - - L - - - BRCA1 C Terminus (BRCT) domain
HEHGKEEJ_00915 8.05e-149 - - - L - - - Resolvase, N terminal domain
HEHGKEEJ_00916 2.25e-64 - - - S - - - Protein of unknown function (DUF1093)
HEHGKEEJ_00917 8.04e-67 - - - S - - - Bacterial toxin of type II toxin-antitoxin system, YafQ
HEHGKEEJ_00918 4.96e-44 - - - L - - - RelB antitoxin
HEHGKEEJ_00919 2.33e-57 - - - L ko:K07483 - ko00000 Homeodomain-like domain
HEHGKEEJ_00920 2.28e-36 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HEHGKEEJ_00921 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HEHGKEEJ_00922 1.83e-59 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HEHGKEEJ_00923 0.0 - - - I - - - Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HEHGKEEJ_00924 5.16e-115 - - - K ko:K21562 - ko00000,ko03000 Transcriptional regulator, Crp Fnr family
HEHGKEEJ_00926 3.81e-88 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HEHGKEEJ_00927 1.74e-92 - - - L ko:K07484 - ko00000 Transposase IS66 family
HEHGKEEJ_00928 3.74e-75 - - - S - - - Phage gp6-like head-tail connector protein
HEHGKEEJ_00929 2.96e-74 - - - S - - - Phage head-tail joining protein
HEHGKEEJ_00930 2.41e-92 - - - S - - - exonuclease activity
HEHGKEEJ_00931 5.13e-84 - - - S - - - Protein of unknown function (DUF806)
HEHGKEEJ_00932 1e-142 - - - S - - - Phage tail tube protein
HEHGKEEJ_00933 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HEHGKEEJ_00934 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HEHGKEEJ_00935 1.31e-286 araT 2.6.1.57 - E ko:K00832,ko:K00841 ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HEHGKEEJ_00936 1.28e-18 - - - - - - - -
HEHGKEEJ_00937 1.51e-200 - - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEHGKEEJ_00938 6.94e-132 msrA 1.8.4.11 - C ko:K07304 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HEHGKEEJ_00939 7.62e-68 yitW - - S - - - Iron-sulfur cluster assembly protein
HEHGKEEJ_00940 8.42e-204 - - - - - - - -
HEHGKEEJ_00941 6.94e-238 - - - - - - - -
HEHGKEEJ_00942 3.61e-117 - - - S - - - Protein conserved in bacteria
HEHGKEEJ_00945 4.41e-89 - - - K - - - Transcriptional regulator
HEHGKEEJ_00946 2.68e-67 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HEHGKEEJ_00947 8.76e-73 ysxB - - J ko:K07584 - ko00000 Cysteine protease Prp
HEHGKEEJ_00948 5.07e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HEHGKEEJ_00949 5.46e-170 - - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HEHGKEEJ_00950 3.85e-259 pepP 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 Creatinase/Prolidase N-terminal domain
HEHGKEEJ_00951 6.38e-159 - - - J - - - 2'-5' RNA ligase superfamily
HEHGKEEJ_00952 2.27e-93 WQ51_04310 - - S ko:K10947 - ko00000,ko03000 Asp23 family, cell envelope-related function
HEHGKEEJ_00953 9.11e-92 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HEHGKEEJ_00954 2.71e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HEHGKEEJ_00955 2.05e-282 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEHGKEEJ_00956 9.86e-59 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HEHGKEEJ_00957 3.59e-207 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HEHGKEEJ_00958 1.69e-192 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 Ribosomal RNA large subunit methyltransferase J
HEHGKEEJ_00959 6.71e-102 argR2 - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HEHGKEEJ_00960 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HEHGKEEJ_00961 9e-72 - - - - - - - -
HEHGKEEJ_00962 1.03e-146 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HEHGKEEJ_00963 6.66e-43 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HEHGKEEJ_00964 1.97e-276 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HEHGKEEJ_00965 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HEHGKEEJ_00966 1.81e-225 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HEHGKEEJ_00967 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HEHGKEEJ_00968 5.19e-169 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HEHGKEEJ_00969 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HEHGKEEJ_00970 1.59e-213 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HEHGKEEJ_00971 5.46e-152 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HEHGKEEJ_00972 6.95e-159 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HEHGKEEJ_00973 1.1e-34 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HEHGKEEJ_00974 1.05e-77 yloU - - S - - - Asp23 family, cell envelope-related function
HEHGKEEJ_00975 0.0 yloV - - S ko:K07030 - ko00000 DAK2 domain fusion protein YloV
HEHGKEEJ_00976 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HEHGKEEJ_00977 1.41e-242 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HEHGKEEJ_00978 1.81e-50 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HEHGKEEJ_00979 1.57e-168 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HEHGKEEJ_00980 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HEHGKEEJ_00981 4.22e-293 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HEHGKEEJ_00982 4.94e-75 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HEHGKEEJ_00983 0.0 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HEHGKEEJ_00984 1.21e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HEHGKEEJ_00985 3.74e-53 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HEHGKEEJ_00986 1.86e-119 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HEHGKEEJ_00987 5.46e-183 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HEHGKEEJ_00988 0.0 - - - E ko:K03294 - ko00000 amino acid
HEHGKEEJ_00989 3.03e-83 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HEHGKEEJ_00990 0.0 - - - L ko:K07484 - ko00000 Transposase IS66 family
HEHGKEEJ_00991 2.8e-81 XK27_01125 - - L ko:K07484 - ko00000 PFAM IS66 Orf2 family protein
HEHGKEEJ_00993 2.29e-130 - - - K - - - Acetyltransferase (GNAT) domain
HEHGKEEJ_00994 4e-313 lmrB - - U ko:K18926 - ko00000,ko00002,ko02000 Belongs to the major facilitator superfamily
HEHGKEEJ_00995 6.69e-304 - - - L - - - Integrase core domain
HEHGKEEJ_00996 1.23e-171 - - - O - - - Bacterial dnaA protein
HEHGKEEJ_00997 1.31e-206 xth 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEHGKEEJ_00998 5.41e-73 - - - S - - - Mazg nucleotide pyrophosphohydrolase
HEHGKEEJ_00999 4.45e-47 - - - - - - - -
HEHGKEEJ_01000 1.06e-228 miaA 2.5.1.75 - F ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HEHGKEEJ_01001 1.18e-30 - - - S - - - Protein of unknown function (DUF3042)
HEHGKEEJ_01002 1.09e-87 yqhL - - P - - - Rhodanese-like protein
HEHGKEEJ_01003 2.51e-235 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HEHGKEEJ_01004 7.07e-48 yqgQ - - S - - - Bacterial protein of unknown function (DUF910)
HEHGKEEJ_01005 2.39e-147 gluP 3.4.21.105 - S ko:K19225 - ko00000,ko01000,ko01002 Peptidase, S54 family
HEHGKEEJ_01006 1.38e-131 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HEHGKEEJ_01007 1.53e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEHGKEEJ_01008 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HEHGKEEJ_01009 0.0 - - - S - - - membrane
HEHGKEEJ_01010 4.64e-92 yneR - - S - - - Belongs to the HesB IscA family
HEHGKEEJ_01011 6.08e-102 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEHGKEEJ_01012 2.06e-152 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HEHGKEEJ_01013 6.17e-151 - - - M - - - PFAM NLP P60 protein
HEHGKEEJ_01014 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEHGKEEJ_01015 3.66e-252 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HEHGKEEJ_01016 4.77e-77 yodB - - K - - - Transcriptional regulator, HxlR family
HEHGKEEJ_01017 3.75e-119 XK27_09705 - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEHGKEEJ_01018 9.44e-187 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEHGKEEJ_01019 1.07e-61 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HEHGKEEJ_01020 9.55e-216 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HEHGKEEJ_01021 5.74e-94 def2 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins
HEHGKEEJ_01022 1.84e-298 - - - V - - - MatE
HEHGKEEJ_01023 0.0 potE - - E - - - Amino Acid
HEHGKEEJ_01024 0.0 arlS 2.7.13.3 - T ko:K18940 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HEHGKEEJ_01025 1.38e-155 csrR - - K - - - response regulator
HEHGKEEJ_01026 7.21e-39 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HEHGKEEJ_01027 1.01e-129 ylbN - - S ko:K07040 - ko00000 Uncharacterized ACR, COG1399
HEHGKEEJ_01028 1.75e-276 ylbM - - S - - - Belongs to the UPF0348 family
HEHGKEEJ_01029 9.84e-183 yqeM - - Q - - - Methyltransferase
HEHGKEEJ_01030 2.3e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HEHGKEEJ_01031 6.21e-147 yqeK - - H - - - Hydrolase, HD family
HEHGKEEJ_01032 1.78e-160 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HEHGKEEJ_01033 5.4e-63 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein
HEHGKEEJ_01034 1.34e-279 yqeH - - S ko:K06948 - ko00000,ko03009 Ribosome biogenesis GTPase YqeH
HEHGKEEJ_01035 1.91e-125 yqeG - - S ko:K07015 - ko00000 HAD phosphatase, family IIIA
HEHGKEEJ_01036 5.46e-74 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HEHGKEEJ_01037 1.82e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HEHGKEEJ_01038 2.15e-110 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HEHGKEEJ_01039 2.57e-223 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HEHGKEEJ_01040 2.83e-299 dnaB - - L ko:K03346 - ko00000,ko03032 replication initiation and membrane attachment
HEHGKEEJ_01041 2.82e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HEHGKEEJ_01042 5.5e-134 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HEHGKEEJ_01043 3.89e-204 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HEHGKEEJ_01044 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HEHGKEEJ_01045 5.87e-155 - - - S - - - Protein of unknown function (DUF1275)
HEHGKEEJ_01046 4.56e-154 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HEHGKEEJ_01047 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HEHGKEEJ_01048 3.43e-154 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HEHGKEEJ_01049 2.95e-75 ytpP - - CO - - - Thioredoxin
HEHGKEEJ_01050 2.27e-75 - - - S - - - Small secreted protein
HEHGKEEJ_01051 6.25e-216 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HEHGKEEJ_01052 2.94e-236 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HEHGKEEJ_01053 0.0 tagE3 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HEHGKEEJ_01054 1.74e-43 - - - A ko:K12092 ko05120,map05120 ko00000,ko00001,ko00002,ko02044 chlorophyll binding
HEHGKEEJ_01055 3.37e-60 - - - S ko:K19055 - ko00000,ko01000,ko03016 Aminoacyl-tRNA editing domain
HEHGKEEJ_01056 0.0 - - - E - - - amino acid
HEHGKEEJ_01057 0.0 ydaO - - E - - - amino acid
HEHGKEEJ_01058 2.63e-53 - - - - - - - -
HEHGKEEJ_01059 3.07e-89 - - - K - - - Transcriptional regulator
HEHGKEEJ_01060 1.06e-159 - - - EGP - - - Major Facilitator
HEHGKEEJ_01061 1.62e-128 - - - EGP - - - Major Facilitator
HEHGKEEJ_01062 4.01e-146 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 YigZ family
HEHGKEEJ_01063 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 Helicase C-terminal domain protein
HEHGKEEJ_01064 7.69e-160 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Competence protein
HEHGKEEJ_01065 3.01e-125 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HEHGKEEJ_01066 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEHGKEEJ_01067 4.72e-240 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HEHGKEEJ_01068 3.65e-67 - - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain protein
HEHGKEEJ_01069 1.88e-68 yvlD - - S ko:K08972 - ko00000 Mycobacterial 4 TMS phage holin, superfamily IV
HEHGKEEJ_01070 1.38e-226 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HEHGKEEJ_01071 4.38e-205 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HEHGKEEJ_01072 5.93e-237 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HEHGKEEJ_01073 1.08e-215 galU 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HEHGKEEJ_01074 4.49e-178 lutC - - S ko:K00782 - ko00000 LUD domain
HEHGKEEJ_01075 0.0 lutB - - C ko:K18929 - ko00000 4Fe-4S dicluster domain
HEHGKEEJ_01076 2.37e-216 lutA - - C ko:K18928 - ko00000 Cysteine-rich domain
HEHGKEEJ_01077 2.04e-223 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HEHGKEEJ_01078 6.35e-276 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEHGKEEJ_01079 5.33e-211 - - - ET ko:K02030 - ko00000,ko00002,ko02000 PFAM extracellular solute-binding protein, family 3
HEHGKEEJ_01080 5.98e-116 ykhA 3.1.2.20 - I ko:K01073 - ko00000,ko01000 Thioesterase superfamily
HEHGKEEJ_01081 0.0 pgm 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HEHGKEEJ_01082 3.57e-150 yfbR - - S ko:K07023 - ko00000 HD containing hydrolase-like enzyme
HEHGKEEJ_01083 2.12e-19 - - - - - - - -
HEHGKEEJ_01084 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HEHGKEEJ_01085 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HEHGKEEJ_01086 9.18e-317 steT - - E ko:K03294 - ko00000 amino acid
HEHGKEEJ_01087 5.67e-208 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HEHGKEEJ_01088 6.97e-240 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HEHGKEEJ_01089 1.37e-218 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HEHGKEEJ_01091 1.83e-21 - - - - - - - -
HEHGKEEJ_01092 4.04e-283 glpT - - G ko:K02445 - ko00000,ko02000 Major Facilitator Superfamily
HEHGKEEJ_01093 4.72e-134 clpP 3.4.21.92 - O ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HEHGKEEJ_01094 0.0 - - - L - - - Transposase
HEHGKEEJ_01096 1.31e-243 gap 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HEHGKEEJ_01097 3.1e-289 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HEHGKEEJ_01098 1.45e-181 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEHGKEEJ_01099 0.0 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HEHGKEEJ_01104 1.58e-169 - - - M - - - Glycosyl hydrolases family 25
HEHGKEEJ_01105 2.64e-19 - - - S - - - COG5546 Small integral membrane protein
HEHGKEEJ_01111 3.98e-133 - - - S - - - EVIDENCE BY HOMOLOGY BIO14.03 Phage related functions and prophages
HEHGKEEJ_01118 4.61e-33 - - - S - - - Phage gp6-like head-tail connector protein
HEHGKEEJ_01119 3.32e-218 - - - S - - - Phage capsid family
HEHGKEEJ_01120 1.2e-80 - 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S14 family
HEHGKEEJ_01121 3.06e-193 - - - S - - - Phage portal protein
HEHGKEEJ_01122 2.05e-315 - - - S - - - Phage Terminase
HEHGKEEJ_01123 1.28e-41 - - - L - - - Phage terminase, small subunit
HEHGKEEJ_01124 6.02e-73 - - - L - - - HNH nucleases
HEHGKEEJ_01125 2.8e-27 rusA - - L - - - holliday junction resolvase
HEHGKEEJ_01128 1.87e-81 - - - V - - - site-specific DNA-methyltransferase (adenine-specific) activity
HEHGKEEJ_01129 6.94e-14 - - - V - - - Type I restriction modification DNA specificity domain
HEHGKEEJ_01130 5.33e-43 - - - - - - - -
HEHGKEEJ_01132 2.34e-41 - - - S ko:K06919 - ko00000 D5 N terminal like
HEHGKEEJ_01138 1.97e-60 - - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_01139 1.6e-121 - - - K - - - Acetyltransferase (GNAT) domain
HEHGKEEJ_01140 5.98e-206 - - - S - - - Alpha beta hydrolase
HEHGKEEJ_01141 9.18e-206 gspA - - M - - - family 8
HEHGKEEJ_01142 7.48e-155 yagB - - S ko:K06950 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HEHGKEEJ_01143 7.18e-126 - - - - - - - -
HEHGKEEJ_01144 5.11e-208 - - - S - - - EDD domain protein, DegV family
HEHGKEEJ_01145 0.0 FbpA - - K - - - Fibronectin-binding protein
HEHGKEEJ_01146 4.45e-93 - - - - - - - -
HEHGKEEJ_01147 3.53e-229 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HEHGKEEJ_01148 4.57e-316 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HEHGKEEJ_01149 2.09e-190 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HEHGKEEJ_01150 5.02e-165 - - - U ko:K02075 - ko00000,ko00002,ko02000 ABC 3 transport family
HEHGKEEJ_01151 3.28e-156 adcC - - P ko:K02074,ko:K09817,ko:K11710 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HEHGKEEJ_01152 8.21e-215 psaA - - P ko:K02077,ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HEHGKEEJ_01153 1.71e-206 ispE 2.7.1.148 - F ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HEHGKEEJ_01154 2.74e-50 veg - - S - - - Biofilm formation stimulator VEG
HEHGKEEJ_01155 3.58e-206 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HEHGKEEJ_01156 1.04e-128 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HEHGKEEJ_01157 1.77e-198 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD family
HEHGKEEJ_01158 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HEHGKEEJ_01159 7.86e-207 yunF - - F - - - Protein of unknown function DUF72
HEHGKEEJ_01161 1.51e-170 cobB - - K ko:K12410 - ko00000,ko01000 SIR2 family
HEHGKEEJ_01162 1.33e-228 - - - - - - - -
HEHGKEEJ_01163 3.28e-296 mvaA 1.1.1.88, 2.3.1.9 - C ko:K00054,ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the HMG-CoA reductase family
HEHGKEEJ_01164 4.38e-215 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEHGKEEJ_01165 1.3e-241 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEHGKEEJ_01166 6.68e-238 - 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 Belongs to the N(4) N(6)-methyltransferase family
HEHGKEEJ_01167 1.17e-105 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Belongs to the NDK family
HEHGKEEJ_01168 0.0 - - - L - - - DNA helicase
HEHGKEEJ_01169 1.57e-260 napA - - P - - - Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HEHGKEEJ_01171 0.0 gabT 2.6.1.19, 5.1.1.21 - E ko:K00823,ko:K20708 ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HEHGKEEJ_01172 0.0 ctrA - - E ko:K03294 - ko00000 amino acid
HEHGKEEJ_01173 8.11e-152 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HEHGKEEJ_01174 9.57e-52 - 1.3.5.4 - S ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FMN binding
HEHGKEEJ_01175 1.63e-278 blt - - EGP ko:K08153 - ko00000,ko00002,ko02000 transporter
HEHGKEEJ_01176 2.09e-216 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HEHGKEEJ_01177 1.45e-198 metQ - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEHGKEEJ_01178 1.04e-245 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HEHGKEEJ_01179 5.25e-140 metI - - P ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01180 6.12e-279 - 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 succinyl-diaminopimelate desuccinylase
HEHGKEEJ_01181 0.0 eriC - - P ko:K03281 - ko00000 chloride
HEHGKEEJ_01182 1.05e-101 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HEHGKEEJ_01183 1.96e-138 - - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, permease protein
HEHGKEEJ_01184 4.13e-180 proV - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01185 2.35e-139 proWZ - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01186 5.3e-209 proWY - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, substrate-binding protein, QAT family
HEHGKEEJ_01187 1.11e-96 ywnA - - K - - - Transcriptional regulator
HEHGKEEJ_01188 6.39e-198 - - - GM - - - NAD(P)H-binding
HEHGKEEJ_01189 4.44e-11 - - - - - - - -
HEHGKEEJ_01190 2.07e-59 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HEHGKEEJ_01191 7.32e-201 - 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Metalloenzyme superfamily
HEHGKEEJ_01192 0.0 cadA - - P - - - P-type ATPase
HEHGKEEJ_01193 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthase
HEHGKEEJ_01194 5.52e-265 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarA family
HEHGKEEJ_01195 7.11e-225 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEHGKEEJ_01196 8.85e-97 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HEHGKEEJ_01197 2.58e-85 esbA - - S - - - Family of unknown function (DUF5322)
HEHGKEEJ_01198 7.66e-92 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease HI
HEHGKEEJ_01199 1.2e-282 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HEHGKEEJ_01200 6.11e-111 - - - F ko:K03647 - ko00000 Belongs to the NrdI family
HEHGKEEJ_01201 6.82e-74 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HEHGKEEJ_01202 1.17e-135 ypsA - - S - - - Belongs to the UPF0398 family
HEHGKEEJ_01203 1.21e-153 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HEHGKEEJ_01204 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein 1A
HEHGKEEJ_01205 2.42e-208 - - - EG - - - EamA-like transporter family
HEHGKEEJ_01206 5e-161 dnaD - - L ko:K02086 - ko00000 DnaD domain protein
HEHGKEEJ_01207 1.15e-115 ypmB - - S - - - Protein conserved in bacteria
HEHGKEEJ_01208 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HEHGKEEJ_01209 1.09e-221 mvk 2.7.1.36 - I ko:K00869 ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146 ko00000,ko00001,ko00002,ko01000 mevalonate kinase
HEHGKEEJ_01210 1.74e-226 mvaD 4.1.1.33 - I ko:K01597 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 diphosphomevalonate decarboxylase
HEHGKEEJ_01211 4.11e-274 mvaK2 2.7.4.2 - I ko:K00938 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 phosphomevalonate kinase
HEHGKEEJ_01212 1.31e-247 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HEHGKEEJ_01213 8.22e-122 - - - S ko:K08996 - ko00000 Protein of unknown function (DUF1440)
HEHGKEEJ_01214 0.0 melA 3.2.1.22 - G ko:K07407 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 alpha-galactosidase
HEHGKEEJ_01215 4.39e-244 galR - - K ko:K02529 - ko00000,ko03000 Periplasmic binding protein-like domain
HEHGKEEJ_01216 5.79e-214 scrK 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 ROK family
HEHGKEEJ_01217 1.19e-229 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEHGKEEJ_01218 6.23e-161 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 LrgB-like family
HEHGKEEJ_01219 3.69e-87 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 LrgA family
HEHGKEEJ_01220 2.9e-169 lytT - - K ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator receiver
HEHGKEEJ_01221 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 LytS YhcK-type transmembrane receptor domain protein
HEHGKEEJ_01222 1.54e-191 - - - O - - - Band 7 protein
HEHGKEEJ_01223 0.0 rsmF - - J - - - NOL1 NOP2 sun family protein
HEHGKEEJ_01224 1.11e-201 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolase
HEHGKEEJ_01225 1.43e-51 - - - S - - - Cytochrome B5
HEHGKEEJ_01226 5.87e-147 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HEHGKEEJ_01227 3.31e-206 - - - K ko:K20480 ko02024,map02024 ko00000,ko00001,ko03000 Helix-turn-helix
HEHGKEEJ_01228 1.18e-76 - - - S - - - Iron-sulfur cluster assembly protein
HEHGKEEJ_01229 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 assembly protein SufB
HEHGKEEJ_01230 5.28e-105 nifU - - C ko:K04488 - ko00000 SUF system FeS assembly protein, NifU family
HEHGKEEJ_01231 3.86e-300 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HEHGKEEJ_01232 4.96e-307 sufD - - O ko:K07033,ko:K09015 - ko00000 FeS assembly protein SufD
HEHGKEEJ_01233 5.43e-185 sufC - - O ko:K09013 - ko00000,ko02000 FeS assembly ATPase SufC
HEHGKEEJ_01234 2.46e-72 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HEHGKEEJ_01235 3.6e-107 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HEHGKEEJ_01236 1.26e-267 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEHGKEEJ_01237 0.0 - - - M - - - Glycosyl transferase family group 2
HEHGKEEJ_01239 9.63e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HEHGKEEJ_01240 8.31e-158 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HEHGKEEJ_01241 1.39e-92 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HEHGKEEJ_01242 1.1e-126 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HEHGKEEJ_01243 7.11e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HEHGKEEJ_01244 9.18e-31 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HEHGKEEJ_01245 1.5e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HEHGKEEJ_01246 2.16e-94 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HEHGKEEJ_01247 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HEHGKEEJ_01248 2.54e-266 yacL - - S - - - domain protein
HEHGKEEJ_01249 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HEHGKEEJ_01250 1.02e-130 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 dUTP diphosphatase
HEHGKEEJ_01251 1.65e-66 yjdJ - - S ko:K06975 - ko00000 GCN5-related N-acetyl-transferase
HEHGKEEJ_01252 2.5e-162 rpiA 5.3.1.6 - G ko:K01807 ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HEHGKEEJ_01253 0.0 pepC 3.4.22.40 - E ko:K01372 - ko00000,ko01000,ko01002 Peptidase C1-like family
HEHGKEEJ_01254 3.01e-181 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HEHGKEEJ_01255 1.75e-173 - - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01256 3.36e-154 tcyB - - E ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEHGKEEJ_01257 4.46e-276 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HEHGKEEJ_01258 1.27e-215 - - - I - - - alpha/beta hydrolase fold
HEHGKEEJ_01259 3.04e-172 gpmA1 5.4.2.11 - G ko:K01834 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HEHGKEEJ_01260 0.0 - - - S - - - Bacterial membrane protein, YfhO
HEHGKEEJ_01261 5.72e-239 lacM 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase
HEHGKEEJ_01262 0.0 lacL 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 2 family
HEHGKEEJ_01264 2e-112 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HEHGKEEJ_01265 2.31e-151 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HEHGKEEJ_01266 0.0 tex - - K ko:K06959 - ko00000 Tex-like protein N-terminal domain protein
HEHGKEEJ_01267 5.27e-197 nadE 6.3.1.5 - F ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HEHGKEEJ_01268 0.0 pncB 6.3.4.21 - F ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HEHGKEEJ_01269 3.54e-165 yvoA_2 - - K ko:K03710 - ko00000,ko03000 UbiC transcription regulator-associated domain protein
HEHGKEEJ_01270 5.9e-170 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HEHGKEEJ_01271 0.0 - - - P ko:K07085 - ko00000 Predicted Permease Membrane Region
HEHGKEEJ_01272 0.0 - - - EGP - - - Major Facilitator
HEHGKEEJ_01273 5.92e-150 - - - - - - - -
HEHGKEEJ_01276 2.01e-206 - - - S - - - Calcineurin-like phosphoesterase
HEHGKEEJ_01277 0.0 dtpT - - U ko:K03305 - ko00000 amino acid peptide transporter
HEHGKEEJ_01280 2.65e-133 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HEHGKEEJ_01281 1.6e-247 - - - S - - - Helix-turn-helix domain
HEHGKEEJ_01282 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase RecQ
HEHGKEEJ_01283 2.15e-83 - - - M - - - Lysin motif
HEHGKEEJ_01284 8.94e-152 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HEHGKEEJ_01285 1.49e-274 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HEHGKEEJ_01286 0.0 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HEHGKEEJ_01287 1.6e-54 hup - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HEHGKEEJ_01288 1.16e-301 XK27_05225 - - S - - - Tetratricopeptide repeat protein
HEHGKEEJ_01289 2.55e-289 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HEHGKEEJ_01290 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01291 1.26e-247 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HEHGKEEJ_01292 4.1e-120 folA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HEHGKEEJ_01293 2.59e-144 hlyIII - - S ko:K11068 - ko00000,ko02042 protein, hemolysin III
HEHGKEEJ_01294 4.49e-196 WQ51_01275 - - S - - - EDD domain protein, DegV family
HEHGKEEJ_01295 7.61e-218 - - - E - - - lipolytic protein G-D-S-L family
HEHGKEEJ_01296 1.16e-140 ypmS - - S - - - Uncharacterized protein conserved in bacteria (DUF2140)
HEHGKEEJ_01297 1.33e-47 yozE - - S - - - Belongs to the UPF0346 family
HEHGKEEJ_01298 1.46e-206 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HEHGKEEJ_01299 9.06e-184 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HEHGKEEJ_01300 1.11e-206 dprA - - LU ko:K04096 - ko00000 DNA protecting protein DprA
HEHGKEEJ_01301 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HEHGKEEJ_01302 1.66e-213 lacX 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HEHGKEEJ_01303 1.56e-138 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HEHGKEEJ_01304 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEHGKEEJ_01305 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HEHGKEEJ_01306 2.41e-111 - - - F - - - NUDIX domain
HEHGKEEJ_01307 1.81e-222 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 inorganic pyrophosphatase
HEHGKEEJ_01308 2.59e-89 - - - S - - - Belongs to the HesB IscA family
HEHGKEEJ_01309 9.14e-66 - - - - - - - -
HEHGKEEJ_01311 7.63e-117 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 Acetyltransferase (GNAT) domain
HEHGKEEJ_01312 8.08e-83 asp1 - - S - - - Asp23 family, cell envelope-related function
HEHGKEEJ_01313 1.04e-33 - - - - - - - -
HEHGKEEJ_01314 1.89e-123 - - - - - - - -
HEHGKEEJ_01315 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HEHGKEEJ_01316 2.04e-234 - - - K ko:K02525 - ko00000,ko03000 Transcriptional regulator, LacI family
HEHGKEEJ_01317 1.47e-241 gntP - - EG ko:K03299 - ko00000,ko02000 Gluconate
HEHGKEEJ_01318 7.74e-173 XK27_07210 - - S - - - B3 4 domain
HEHGKEEJ_01319 8.16e-103 yybA - - K - - - Transcriptional regulator
HEHGKEEJ_01320 1.51e-117 - - - K - - - Domain of unknown function (DUF1836)
HEHGKEEJ_01321 1.9e-115 - - - GM - - - epimerase
HEHGKEEJ_01322 4.66e-197 - - - V - - - (ABC) transporter
HEHGKEEJ_01323 4.1e-308 yhdP - - S - - - Transporter associated domain
HEHGKEEJ_01324 1.15e-109 nrdI - - F ko:K03647 - ko00000 Belongs to the NrdI family
HEHGKEEJ_01325 2.59e-97 - - - S ko:K04750 - ko00000 3-demethylubiquinone-9 3-methyltransferase
HEHGKEEJ_01326 3.75e-246 yycB - - P ko:K03449 - ko00000,ko02000 Transporter, major facilitator family protein
HEHGKEEJ_01327 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HEHGKEEJ_01328 0.0 gnd 1.1.1.343, 1.1.1.44 - H ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HEHGKEEJ_01329 4.48e-55 - - - - - - - -
HEHGKEEJ_01330 0.0 lacS - - G ko:K11104,ko:K16209 - ko00000,ko02000 Transporter
HEHGKEEJ_01331 1.36e-99 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HEHGKEEJ_01332 5.13e-46 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HEHGKEEJ_01333 2.71e-103 usp5 - - T - - - universal stress protein
HEHGKEEJ_01334 3.83e-104 - - - K ko:K03719 - ko00000,ko03000,ko03036 AsnC family
HEHGKEEJ_01335 5.61e-292 gltT - - U ko:K03309,ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HEHGKEEJ_01336 1.09e-134 apl 3.1.3.1 - S ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 SNARE associated Golgi protein
HEHGKEEJ_01337 2.92e-233 galR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HEHGKEEJ_01338 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HEHGKEEJ_01339 1.08e-289 galK 2.7.1.6 - F ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HEHGKEEJ_01340 7.24e-239 celE3 - - E - - - GDSL-like Lipase/Acylhydrolase family
HEHGKEEJ_01341 4.87e-190 - 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Tyrosine phosphatase family
HEHGKEEJ_01342 1.65e-122 - - - S ko:K06910 - ko00000 Phosphatidylethanolamine-binding protein
HEHGKEEJ_01343 1.21e-48 - - - - - - - -
HEHGKEEJ_01344 4.33e-69 - - - - - - - -
HEHGKEEJ_01345 2.72e-262 - - - - - - - -
HEHGKEEJ_01346 8.19e-108 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HEHGKEEJ_01347 5.87e-177 pnuC - - H ko:K03811 - ko00000,ko02000 nicotinamide mononucleotide transporter
HEHGKEEJ_01348 1.3e-204 yvgN - - S - - - Aldo keto reductase
HEHGKEEJ_01349 6.91e-164 XK27_10500 - - K - - - response regulator
HEHGKEEJ_01350 7.79e-236 - - - T - - - Histidine kinase-like ATPases
HEHGKEEJ_01351 5.22e-176 XK27_05695 - - V ko:K02003,ko:K19083 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01352 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 FtsX-like permease family
HEHGKEEJ_01353 1.78e-204 metA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to
HEHGKEEJ_01354 2.75e-215 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEHGKEEJ_01355 9.45e-145 - - - S - - - Haloacid dehalogenase-like hydrolase
HEHGKEEJ_01356 6.66e-151 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HEHGKEEJ_01357 1.96e-167 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HEHGKEEJ_01358 2.77e-220 pyrD 1.3.1.14, 1.3.98.1 - F ko:K00226,ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HEHGKEEJ_01359 3.19e-315 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HEHGKEEJ_01360 1.81e-221 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HEHGKEEJ_01361 1.56e-20 - - - K - - - LysR substrate binding domain
HEHGKEEJ_01362 5.46e-153 - - - K ko:K09681 - ko00000,ko03000 DNA-binding transcription factor activity
HEHGKEEJ_01363 4.73e-69 - - - S - - - branched-chain amino acid
HEHGKEEJ_01364 6.03e-196 - - - E - - - AzlC protein
HEHGKEEJ_01365 1.36e-266 hpk31 - - T - - - Histidine kinase
HEHGKEEJ_01366 9.76e-161 vanR - - K - - - response regulator
HEHGKEEJ_01367 1.47e-265 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HEHGKEEJ_01368 2.28e-220 deoR - - K ko:K05346 - ko00000,ko03000 sugar-binding domain protein
HEHGKEEJ_01369 3.27e-167 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HEHGKEEJ_01370 4.23e-305 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 pyrimidine-nucleoside phosphorylase
HEHGKEEJ_01371 8.02e-299 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HEHGKEEJ_01372 6.58e-152 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HEHGKEEJ_01373 6.3e-175 - - - S - - - Protein of unknown function (DUF1129)
HEHGKEEJ_01374 6.1e-255 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HEHGKEEJ_01375 8.24e-43 yyzM - - S - - - Bacterial protein of unknown function (DUF951)
HEHGKEEJ_01376 3.96e-197 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEHGKEEJ_01377 8.34e-180 soj - - D ko:K03496 - ko00000,ko03036,ko04812 Sporulation initiation inhibitor
HEHGKEEJ_01378 3.57e-198 noc - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HEHGKEEJ_01379 9.71e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of a guanine in 16S rRNA
HEHGKEEJ_01380 1.08e-210 - 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 3-hydroxyacyl-CoA dehydrogenase
HEHGKEEJ_01381 2.47e-220 rihA 3.2.2.1 - F ko:K01239,ko:K01250,ko:K12700 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 Nucleoside
HEHGKEEJ_01382 1.69e-278 nupG - - F ko:K03317,ko:K11535,ko:K16323 - ko00000,ko02000 Nucleoside transporter
HEHGKEEJ_01383 2.25e-288 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 Amino acid permease
HEHGKEEJ_01384 3.99e-178 glnQ 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01385 0.0 glnP - - P ko:K02029,ko:K02030,ko:K10036 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEHGKEEJ_01386 0.0 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HEHGKEEJ_01387 0.0 - - - D - - - Domain of Unknown Function (DUF1542)
HEHGKEEJ_01388 2.84e-27 - - - D - - - Domain of Unknown Function (DUF1542)
HEHGKEEJ_01389 0.0 cshA 3.6.4.13 - F ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HEHGKEEJ_01390 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HEHGKEEJ_01391 2.61e-204 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HEHGKEEJ_01392 4.93e-123 lemA - - S ko:K03744 - ko00000 LemA family
HEHGKEEJ_01393 3.3e-113 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEHGKEEJ_01394 1.45e-152 - - - G - - - Belongs to the phosphoglycerate mutase family
HEHGKEEJ_01395 1.59e-209 fba 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Fructose-1,6-bisphosphate aldolase, class II
HEHGKEEJ_01396 3.01e-179 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEHGKEEJ_01397 4.29e-162 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HEHGKEEJ_01398 3.35e-215 - - - S - - - Alpha/beta hydrolase of unknown function (DUF915)
HEHGKEEJ_01399 2.02e-306 pts13C - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HEHGKEEJ_01400 9.43e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HEHGKEEJ_01401 1.58e-301 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEHGKEEJ_01402 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HEHGKEEJ_01403 2.68e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HEHGKEEJ_01404 6.79e-91 ywiB - - S - - - Domain of unknown function (DUF1934)
HEHGKEEJ_01405 3.43e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 biotin lipoate A B protein ligase
HEHGKEEJ_01406 0.0 ywfO - - S ko:K06885 - ko00000 HD domain protein
HEHGKEEJ_01407 1.14e-190 yidA - - S - - - hydrolase
HEHGKEEJ_01408 0.0 yhgE - - V ko:K01421 - ko00000 domain protein
HEHGKEEJ_01409 2.14e-123 - - - K - - - Transcriptional regulator (TetR family)
HEHGKEEJ_01410 6.09e-53 pspC - - KT ko:K03973 - ko00000,ko02048,ko03000 positive regulation of macromolecule biosynthetic process
HEHGKEEJ_01411 3.42e-195 - - - - - - - -
HEHGKEEJ_01412 1.37e-40 - 3.2.1.14 GH18 - ko:K01183 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 -
HEHGKEEJ_01413 1.27e-108 zur - - P ko:K02076,ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HEHGKEEJ_01414 5.82e-136 gmk2 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Guanylate kinase
HEHGKEEJ_01415 2.53e-97 - - - F - - - Nudix hydrolase
HEHGKEEJ_01416 0.0 yhdG - - E ko:K03294 - ko00000 Amino Acid
HEHGKEEJ_01417 5.29e-300 - - - EGP ko:K08368 - ko00000,ko02000 Sugar (and other) transporter
HEHGKEEJ_01418 1.06e-297 - - - - - - - -
HEHGKEEJ_01419 1.03e-267 potD - - P ko:K11069 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEHGKEEJ_01420 5.39e-184 potC - - P ko:K11070 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01421 2.49e-187 potB - - P ko:K11071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01422 1.25e-262 potA 3.6.3.30, 3.6.3.31 - P ko:K02010,ko:K11072 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HEHGKEEJ_01423 0.0 pepX 3.4.14.11 - E ko:K01281 - ko00000,ko01000,ko01002 Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HEHGKEEJ_01424 1.5e-226 pepR 3.4.11.5 - E ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Releases the N-terminal proline from various substrates
HEHGKEEJ_01425 0.0 atp2C1 3.6.3.8 - P ko:K01537 - ko00000,ko01000 P-type ATPase
HEHGKEEJ_01426 2.93e-112 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HEHGKEEJ_01427 0.0 yagE - - E - - - amino acid
HEHGKEEJ_01428 4.01e-153 - - - S - - - HAD hydrolase, family IA, variant
HEHGKEEJ_01429 1.24e-37 - - - S - - - PD-(D/E)XK nuclease family transposase
HEHGKEEJ_01430 3.33e-33 - - - L - - - Helix-turn-helix domain
HEHGKEEJ_01431 1.43e-109 - - - L - - - Helix-turn-helix domain
HEHGKEEJ_01432 2.23e-163 - - - L ko:K07497 - ko00000 hmm pf00665
HEHGKEEJ_01433 1.51e-236 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HEHGKEEJ_01434 1.1e-232 iunH1 3.2.2.1 - F ko:K01239 ko00230,ko00760,ko01100,map00230,map00760,map01100 ko00000,ko00001,ko01000 nucleoside hydrolase
HEHGKEEJ_01435 2.21e-177 - - - IQ - - - KR domain
HEHGKEEJ_01436 1.35e-239 - - - L - - - PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HEHGKEEJ_01437 6.74e-76 traI 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 DNA topoisomerase
HEHGKEEJ_01444 9.96e-147 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HEHGKEEJ_01445 2.01e-81 - - - L - - - Integrase
HEHGKEEJ_01446 1.18e-24 - - - D - - - Glucan-binding protein C
HEHGKEEJ_01447 1.05e-213 - - - L ko:K07496 - ko00000 transposase, IS605 OrfB family
HEHGKEEJ_01448 6.68e-85 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 sortase family
HEHGKEEJ_01454 6.98e-95 - - - - - - - -
HEHGKEEJ_01456 1.25e-54 - - - S - - - Putative peptidoglycan binding domain
HEHGKEEJ_01457 2.13e-142 nnrE 5.1.99.6 - H ko:K17759 - ko00000,ko01000 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HEHGKEEJ_01458 1.04e-114 - - - - - - - -
HEHGKEEJ_01459 1.61e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HEHGKEEJ_01460 5.21e-275 yttB - - EGP - - - Major Facilitator
HEHGKEEJ_01461 1.03e-146 - - - - - - - -
HEHGKEEJ_01462 2.6e-33 - - - - - - - -
HEHGKEEJ_01463 7.96e-223 scrR - - K ko:K02529,ko:K03484 - ko00000,ko03000 Transcriptional regulator, LacI family
HEHGKEEJ_01464 0.0 - 3.2.1.17 CBM50 NU ko:K01185,ko:K02395,ko:K19223 - ko00000,ko01000,ko01002,ko01011,ko02035 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HEHGKEEJ_01465 1.36e-66 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HEHGKEEJ_01466 9.71e-50 - - - - - - - -
HEHGKEEJ_01467 0.0 yhcA - - V ko:K02003,ko:K02004 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01468 2.58e-156 lolD - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01469 2.5e-236 yxeA - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01470 5.75e-117 - - - K - - - transcriptional regulator (TetR family)
HEHGKEEJ_01471 9.96e-244 - - - E - - - Zinc-binding dehydrogenase
HEHGKEEJ_01472 0.0 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEHGKEEJ_01473 2.09e-86 - - - - - - - -
HEHGKEEJ_01474 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HEHGKEEJ_01476 2.99e-289 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 Vacuole effluxer Atg22 like
HEHGKEEJ_01477 0.0 npp - - S - - - type I phosphodiesterase nucleotide pyrophosphatase
HEHGKEEJ_01478 9.08e-317 - - - E ko:K03294 - ko00000 amino acid
HEHGKEEJ_01479 1.46e-236 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HEHGKEEJ_01481 2.33e-39 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HEHGKEEJ_01482 9.7e-06 - - - S - - - Protein of unknown function (DUF3278)
HEHGKEEJ_01483 2.61e-283 - 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 methionine synthase, vitamin-B12 independent
HEHGKEEJ_01489 2.21e-32 - - - - - - - -
HEHGKEEJ_01491 2.87e-12 - - - T - - - PFAM SpoVT AbrB
HEHGKEEJ_01492 1.56e-37 - - - T ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HEHGKEEJ_01494 7.76e-05 - - - - - - - -
HEHGKEEJ_01497 3.25e-17 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HEHGKEEJ_01502 4.38e-55 - - - - - - - -
HEHGKEEJ_01503 2.19e-55 - - - DJ - - - Addiction module toxin, RelE
HEHGKEEJ_01507 1.14e-18 - - - - - - - -
HEHGKEEJ_01514 5.28e-47 - - - M - - - LysM domain protein
HEHGKEEJ_01515 1.5e-54 - - - M - - - ErfK YbiS YcfS YnhG
HEHGKEEJ_01516 7.72e-138 ypuA - - S - - - Protein of unknown function (DUF1002)
HEHGKEEJ_01518 1.38e-192 - 2.1.1.72 - L ko:K00571,ko:K07316 - ko00000,ko01000,ko02048 DNA methylase
HEHGKEEJ_01519 4.12e-145 sthIR 3.1.21.5 - L ko:K01156 - ko00000,ko01000,ko02048 Type III restriction enzyme, res subunit
HEHGKEEJ_01520 2e-108 - - - L - - - Integrase
HEHGKEEJ_01524 2.28e-26 - - - L - - - Helicase C-terminal domain protein
HEHGKEEJ_01525 2.79e-61 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 NUDIX domain
HEHGKEEJ_01526 0.0 rumA_2 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HEHGKEEJ_01527 5.96e-40 - - - S ko:K07341 - ko00000,ko02048 Fic/DOC family
HEHGKEEJ_01529 2.72e-237 dagK 2.7.1.107 - G ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 Lipid kinase
HEHGKEEJ_01530 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEHGKEEJ_01531 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HEHGKEEJ_01532 1.36e-66 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HEHGKEEJ_01533 3.17e-260 camS - - S - - - sex pheromone
HEHGKEEJ_01534 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HEHGKEEJ_01535 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HEHGKEEJ_01536 3.24e-272 purK2 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HEHGKEEJ_01537 6.76e-131 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HEHGKEEJ_01538 5.09e-148 acmA 3.2.1.17, 3.2.1.96 - NU ko:K01185,ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 mannosyl-glycoprotein
HEHGKEEJ_01539 1.56e-180 budC 1.1.1.304, 1.1.1.76 - IQ ko:K03366 ko00650,map00650 ko00000,ko00001,ko01000 reductase
HEHGKEEJ_01540 3.94e-85 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HEHGKEEJ_01541 9.25e-103 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HEHGKEEJ_01542 1.23e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HEHGKEEJ_01543 5.82e-181 ecfT - - U ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEHGKEEJ_01544 2.6e-199 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEHGKEEJ_01545 2.21e-189 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HEHGKEEJ_01546 8.08e-83 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HEHGKEEJ_01547 2.19e-220 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEHGKEEJ_01548 1.62e-83 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HEHGKEEJ_01549 1.54e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HEHGKEEJ_01550 5.79e-21 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HEHGKEEJ_01551 2.41e-45 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HEHGKEEJ_01552 4.52e-161 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HEHGKEEJ_01553 2.88e-306 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEHGKEEJ_01554 6.05e-93 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to the 23S rRNA
HEHGKEEJ_01555 5.94e-34 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HEHGKEEJ_01556 5.95e-112 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HEHGKEEJ_01557 5.03e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HEHGKEEJ_01558 2.6e-124 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HEHGKEEJ_01559 1.54e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HEHGKEEJ_01560 4.97e-40 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HEHGKEEJ_01561 7.42e-125 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HEHGKEEJ_01562 2.58e-65 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HEHGKEEJ_01563 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HEHGKEEJ_01564 1.1e-55 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HEHGKEEJ_01565 5.49e-38 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HEHGKEEJ_01566 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HEHGKEEJ_01567 9.81e-157 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HEHGKEEJ_01568 4.36e-70 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HEHGKEEJ_01569 5.72e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HEHGKEEJ_01570 1.16e-203 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HEHGKEEJ_01571 3.61e-61 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HEHGKEEJ_01572 3.84e-138 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HEHGKEEJ_01573 5.45e-153 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HEHGKEEJ_01574 1.28e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HEHGKEEJ_01575 2.58e-254 - - - L - - - Transposase
HEHGKEEJ_01576 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HEHGKEEJ_01577 2.06e-108 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HEHGKEEJ_01578 3.56e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HEHGKEEJ_01579 1.44e-155 comC 3.4.23.43 - NOU ko:K02236 - ko00000,ko00002,ko01000,ko02044 Bacterial Peptidase A24 N-terminal domain
HEHGKEEJ_01580 3.31e-263 - - - - - - - -
HEHGKEEJ_01581 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEHGKEEJ_01582 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HEHGKEEJ_01583 2.09e-143 - - - K - - - Bacterial regulatory proteins, tetR family
HEHGKEEJ_01584 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HEHGKEEJ_01585 1.39e-101 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HEHGKEEJ_01586 1.8e-249 adhP 1.1.1.1 - C ko:K00001,ko:K13953 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEHGKEEJ_01587 7.53e-191 - - - S ko:K06889 - ko00000 Hydrolases of the alpha beta superfamily
HEHGKEEJ_01590 2.14e-24 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HEHGKEEJ_01592 1.65e-36 - - - - - - - -
HEHGKEEJ_01593 2.09e-21 - - - S - - - Helix-turn-helix domain
HEHGKEEJ_01594 1.89e-12 ansR - - K - - - Transcriptional regulator
HEHGKEEJ_01595 7.91e-53 - - - L - - - Phage integrase, N-terminal SAM-like domain
HEHGKEEJ_01601 7.78e-150 dgk2 - - F - - - deoxynucleoside kinase
HEHGKEEJ_01602 0.0 lysP - - E ko:K03293,ko:K11733 - ko00000,ko02000 amino acid
HEHGKEEJ_01603 8.71e-07 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HEHGKEEJ_01604 9.35e-152 - - - I - - - phosphatase
HEHGKEEJ_01605 1.06e-106 - - - S - - - Threonine/Serine exporter, ThrE
HEHGKEEJ_01606 7.95e-171 - - - S - - - Putative threonine/serine exporter
HEHGKEEJ_01607 2.17e-43 cspC - - K ko:K03704 - ko00000,ko03000 Cold shock protein
HEHGKEEJ_01608 2.32e-161 mntR - - K ko:K03709 - ko00000,ko03000 iron dependent repressor
HEHGKEEJ_01609 4.04e-212 - - - P ko:K16264 - ko00000,ko02000 cation diffusion facilitator family transporter
HEHGKEEJ_01610 8.93e-153 - - - S - - - membrane
HEHGKEEJ_01611 1.35e-141 - - - S - - - VIT family
HEHGKEEJ_01612 4.83e-108 - - - T - - - Belongs to the universal stress protein A family
HEHGKEEJ_01613 4.64e-172 glnQ - - E ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01614 9.45e-196 peb1A - - ET ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEHGKEEJ_01615 5.24e-143 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01616 3.65e-141 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter permease
HEHGKEEJ_01617 8.11e-282 - - - S ko:K07052 - ko00000 CAAX protease self-immunity
HEHGKEEJ_01618 0.0 rnjA - - J ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HEHGKEEJ_01619 8.46e-77 - - - - - - - -
HEHGKEEJ_01620 5.33e-98 - - - K - - - MerR HTH family regulatory protein
HEHGKEEJ_01621 0.0 ycnB - - U - - - Belongs to the major facilitator superfamily
HEHGKEEJ_01622 6.51e-161 - - - S - - - Domain of unknown function (DUF4811)
HEHGKEEJ_01623 2.75e-211 yjbO 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HEHGKEEJ_01625 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HEHGKEEJ_01626 4.55e-121 - 3.5.1.124 - S ko:K03152 - ko00000,ko01000,ko01002 DJ-1/PfpI family
HEHGKEEJ_01627 2.74e-241 - - - I - - - Alpha beta
HEHGKEEJ_01628 0.0 qacA - - EGP - - - Major Facilitator
HEHGKEEJ_01629 7.76e-152 - 3.2.2.27 - L ko:K21929 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Uracil-DNA glycosylase
HEHGKEEJ_01630 0.0 - - - S - - - Putative threonine/serine exporter
HEHGKEEJ_01631 7.21e-205 - - - K - - - LysR family
HEHGKEEJ_01632 1.03e-142 - - - I - - - Alpha/beta hydrolase family
HEHGKEEJ_01633 1.56e-193 citG 2.4.2.52 - H ko:K05966 ko02020,map02020 ko00000,ko00001,ko01000 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HEHGKEEJ_01634 0.0 citF 2.8.3.10 - H ko:K01643 ko02020,map02020 ko00000,ko00001,ko01000 Citrate (pro-3S)-lyase alpha chain
HEHGKEEJ_01635 3.29e-204 citE 4.1.3.34 - G ko:K01644 ko02020,map02020 ko00000,ko00001,ko01000 Belongs to the HpcH HpaI aldolase family
HEHGKEEJ_01636 2.56e-56 citD - - C ko:K01646 ko02020,map02020 ko00000,ko00001 Covalent carrier of the coenzyme of citrate lyase
HEHGKEEJ_01637 9.38e-188 citC 6.2.1.22 - H ko:K01910 ko02020,map02020 ko00000,ko00001,ko01000 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HEHGKEEJ_01638 1.15e-223 mae 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme, NAD binding domain
HEHGKEEJ_01639 2.38e-155 citR - - K - - - sugar-binding domain protein
HEHGKEEJ_01640 1.01e-214 citP - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HEHGKEEJ_01641 1.85e-163 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HEHGKEEJ_01642 0.0 frdA 1.3.5.4 - C ko:K00244 ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020 ko00000,ko00001,ko00002,ko01000 FAD binding domain
HEHGKEEJ_01643 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HEHGKEEJ_01644 2.97e-243 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HEHGKEEJ_01645 3.14e-119 mleS 1.1.1.38, 4.1.1.101 - C ko:K00027,ko:K22212 ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020 ko00000,ko00001,ko01000 Malic enzyme
HEHGKEEJ_01646 1.3e-206 mleR - - K - - - LysR family
HEHGKEEJ_01648 2.8e-159 yrkL - - S - - - Flavodoxin-like fold
HEHGKEEJ_01649 8.14e-73 - - - - - - - -
HEHGKEEJ_01651 3.19e-182 - - - S - - - PD-(D/E)XK nuclease family transposase
HEHGKEEJ_01652 2.48e-66 - - - - - - - -
HEHGKEEJ_01653 5.51e-264 yngD - - S ko:K07097 - ko00000 DHHA1 domain
HEHGKEEJ_01654 2.81e-297 - - - S - - - Uncharacterized protein conserved in bacteria (DUF2325)
HEHGKEEJ_01655 0.0 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEHGKEEJ_01656 1.79e-138 - - - NU - - - mannosyl-glycoprotein
HEHGKEEJ_01657 1.57e-190 - - - S - - - Putative ABC-transporter type IV
HEHGKEEJ_01658 0.0 - - - S - - - ABC transporter, ATP-binding protein
HEHGKEEJ_01661 1.15e-139 - - - S - - - Protein of unknown function (DUF3278)
HEHGKEEJ_01662 3.01e-19 - - - L ko:K07473 - ko00000,ko02048 RelB antitoxin
HEHGKEEJ_01663 6.32e-171 - - - M - - - PFAM NLP P60 protein
HEHGKEEJ_01664 4.49e-233 ABC-SBP - - S ko:K01989 - ko00000,ko00002,ko02000 ABC transporter
HEHGKEEJ_01665 6.8e-196 XK27_08840 - - U ko:K05832 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HEHGKEEJ_01666 3.96e-177 XK27_08845 - - S ko:K05833 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01667 6.27e-125 - - - P - - - Cadmium resistance transporter
HEHGKEEJ_01668 1.14e-74 czrA - - K ko:K22043 - ko00000,ko03000 Transcriptional regulator, ArsR family
HEHGKEEJ_01669 1.94e-305 mepA - - V ko:K18908 - ko00000,ko00002,ko01504,ko02000 MATE efflux family protein
HEHGKEEJ_01670 6.46e-74 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HEHGKEEJ_01671 3.78e-169 yceF - - P ko:K05794 - ko00000 membrane
HEHGKEEJ_01672 4.92e-213 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HEHGKEEJ_01673 6.47e-213 corA - - P ko:K03284 - ko00000,ko02000 CorA-like Mg2+ transporter protein
HEHGKEEJ_01674 0.0 pepD1 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEHGKEEJ_01675 2.77e-306 pbuX - - F ko:K03458,ko:K16169 - ko00000,ko02000 xanthine permease
HEHGKEEJ_01676 6.17e-202 - - - - - - - -
HEHGKEEJ_01677 4.29e-311 - - - M - - - Glycosyl transferase
HEHGKEEJ_01678 1.85e-288 - - - G - - - Glycosyl hydrolases family 8
HEHGKEEJ_01679 6.61e-180 nfrA 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 nitroreductase
HEHGKEEJ_01680 0.0 mycA 4.2.1.53 - S ko:K10254 - ko00000,ko01000 Myosin-crossreactive antigen
HEHGKEEJ_01681 4.98e-307 ktrB - - P ko:K03498 - ko00000,ko02000 Potassium uptake protein
HEHGKEEJ_01682 2.68e-150 ktrA - - P ko:K03499 - ko00000,ko02000 domain protein
HEHGKEEJ_01683 3.1e-113 - - - Q - - - Methyltransferase
HEHGKEEJ_01684 5.41e-293 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HEHGKEEJ_01685 1.1e-227 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HEHGKEEJ_01686 1.13e-217 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HEHGKEEJ_01687 1.44e-121 - - - S - - - NADPH-dependent FMN reductase
HEHGKEEJ_01688 1.67e-229 - - - S - - - Conserved hypothetical protein 698
HEHGKEEJ_01689 6.66e-177 - - - I - - - alpha/beta hydrolase fold
HEHGKEEJ_01690 1.03e-209 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HEHGKEEJ_01691 2.08e-50 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HEHGKEEJ_01692 1.26e-64 yjcA - - S ko:K19350 ko02010,map02010 ko00000,ko00001,ko01504,ko02000 ABC transporter
HEHGKEEJ_01693 1.56e-229 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Peroxidase
HEHGKEEJ_01694 0.0 arcD - - S - - - C4-dicarboxylate anaerobic carrier
HEHGKEEJ_01695 0.0 arcT - - E - - - Dipeptidase
HEHGKEEJ_01696 1.05e-273 - - - EGP - - - Transporter, major facilitator family protein
HEHGKEEJ_01697 0.0 gtfA 2.4.1.7 GH13 G ko:K00690 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose glucosyltransferase
HEHGKEEJ_01698 1.95e-178 - - - V - - - Beta-lactamase enzyme family
HEHGKEEJ_01699 1.73e-288 dacA 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HEHGKEEJ_01700 5.36e-97 - - - - - - - -
HEHGKEEJ_01701 0.0 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HEHGKEEJ_01702 1e-47 dltC 6.1.1.13 - J ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEHGKEEJ_01703 9.07e-300 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 MBOAT, membrane-bound O-acyltransferase family
HEHGKEEJ_01704 0.0 dltA 6.1.1.13 - H ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HEHGKEEJ_01705 2.63e-08 dltX - - S - - - D-Ala-teichoic acid biosynthesis protein
HEHGKEEJ_01706 2.29e-81 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HEHGKEEJ_01707 1.87e-270 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HEHGKEEJ_01708 6.84e-55 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HEHGKEEJ_01709 0.0 - - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HEHGKEEJ_01710 9.6e-310 codA 3.5.4.1 - F ko:K01485 ko00240,ko00330,ko01100,map00240,map00330,map01100 ko00000,ko00001,ko01000 cytosine deaminase
HEHGKEEJ_01711 2.06e-188 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HEHGKEEJ_01712 8.08e-147 - - - S - - - (CBS) domain
HEHGKEEJ_01713 1.38e-132 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HEHGKEEJ_01714 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HEHGKEEJ_01715 4.11e-52 yabO - - J - - - S4 domain protein
HEHGKEEJ_01716 4.31e-76 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HEHGKEEJ_01717 5.75e-103 yabR - - J ko:K07571 - ko00000 RNA binding
HEHGKEEJ_01718 0.0 tilS 2.4.2.8, 6.3.4.19 - J ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HEHGKEEJ_01719 5.23e-125 hpt 2.4.2.8 - F ko:K00760 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the purine pyrimidine phosphoribosyltransferase family
HEHGKEEJ_01720 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HEHGKEEJ_01721 2.77e-219 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HEHGKEEJ_01722 2.17e-241 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HEHGKEEJ_01723 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HEHGKEEJ_01724 6.85e-115 - - - - - - - -
HEHGKEEJ_01725 1.19e-173 - - - S ko:K07009 - ko00000 CobB/CobQ-like glutamine amidotransferase domain
HEHGKEEJ_01726 0.0 murE2 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Mur ligase, middle domain
HEHGKEEJ_01727 6.8e-140 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HEHGKEEJ_01728 1.73e-248 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HEHGKEEJ_01729 7.63e-217 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HEHGKEEJ_01730 6.56e-252 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HEHGKEEJ_01731 3.82e-295 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HEHGKEEJ_01732 6.68e-150 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HEHGKEEJ_01733 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HEHGKEEJ_01734 2.45e-248 yibE - - S - - - overlaps another CDS with the same product name
HEHGKEEJ_01735 4.22e-169 yibF - - S - - - overlaps another CDS with the same product name
HEHGKEEJ_01736 9.91e-80 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HEHGKEEJ_01737 1.41e-191 pyrP - - F ko:K02824 - ko00000,ko02000 Permease
HEHGKEEJ_01738 4.63e-162 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HEHGKEEJ_01739 1.26e-29 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEHGKEEJ_01740 1.07e-95 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HEHGKEEJ_01741 6.84e-121 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HEHGKEEJ_01742 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HEHGKEEJ_01743 1.3e-212 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HEHGKEEJ_01744 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HEHGKEEJ_01745 8.95e-90 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HEHGKEEJ_01746 1.76e-45 ywzB - - S - - - Protein of unknown function (DUF1146)
HEHGKEEJ_01747 7.7e-311 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HEHGKEEJ_01748 1.49e-226 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Cell shape determining protein MreB Mrl
HEHGKEEJ_01749 7.96e-45 - - - S - - - Protein of unknown function (DUF2969)
HEHGKEEJ_01750 4.7e-282 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HEHGKEEJ_01751 2.98e-64 gcsH2 - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 glycine cleavage
HEHGKEEJ_01752 1.7e-163 - - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_01767 2.2e-120 - - - - - - - -
HEHGKEEJ_01768 0.0 - - - U - - - Psort location Cytoplasmic, score
HEHGKEEJ_01769 3.37e-123 - - - - - - - -
HEHGKEEJ_01771 2.39e-225 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HEHGKEEJ_01772 6.45e-284 - - - S ko:K07133 - ko00000 cog cog1373
HEHGKEEJ_01774 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HEHGKEEJ_01783 1.83e-63 - - - D - - - nuclear chromosome segregation
HEHGKEEJ_01784 1.15e-05 - - - D - - - nuclear chromosome segregation
HEHGKEEJ_01791 1.17e-100 - - - L - - - Phage integrase family
HEHGKEEJ_01792 2.39e-64 - - - - - - - -
HEHGKEEJ_01794 1.9e-61 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HEHGKEEJ_01795 2.79e-75 XK27_06915 - - K ko:K10947 - ko00000,ko03000 transcriptional regulator PadR family
HEHGKEEJ_01796 2.68e-127 - - - S - - - Protein of unknown function (DUF1700)
HEHGKEEJ_01797 6.81e-172 - - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HEHGKEEJ_01798 0.0 adhE 1.1.1.1, 1.2.1.10 - C ko:K04072 ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 belongs to the iron- containing alcohol dehydrogenase family
HEHGKEEJ_01799 7.68e-254 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEHGKEEJ_01800 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HEHGKEEJ_01801 9.33e-48 nrdH - - O ko:K06191 - ko00000 Glutaredoxin
HEHGKEEJ_01802 6.21e-119 tadA 3.5.4.33 - F ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HEHGKEEJ_01803 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HEHGKEEJ_01804 5.87e-62 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HEHGKEEJ_01805 4.92e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HEHGKEEJ_01806 4.67e-52 - - - S - - - Protein of unknown function (DUF2508)
HEHGKEEJ_01807 5.48e-150 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HEHGKEEJ_01808 2.83e-69 yaaQ - - S - - - Cyclic-di-AMP receptor
HEHGKEEJ_01809 1.29e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HEHGKEEJ_01810 3.71e-76 yabA - - L - - - Involved in initiation control of chromosome replication
HEHGKEEJ_01811 5.48e-201 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HEHGKEEJ_01812 1.82e-177 fat 3.1.2.21 - I ko:K01071 ko00061,ko01100,map00061,map01100 ko00000,ko00001,ko01000,ko01004 Acyl-ACP thioesterase
HEHGKEEJ_01813 0.0 ppx3 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEHGKEEJ_01814 0.0 ppk 2.7.4.1 - P ko:K00937 ko00190,ko03018,map00190,map03018 ko00000,ko00001,ko01000,ko03019 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HEHGKEEJ_01815 5.83e-225 ppx 3.6.1.11, 3.6.1.40 - FP ko:K01524 ko00230,map00230 ko00000,ko00001,ko01000 exopolyphosphatase
HEHGKEEJ_01816 1.48e-247 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HEHGKEEJ_01817 1.61e-54 isp - - L - - - Transposase
HEHGKEEJ_01818 9.45e-168 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase
HEHGKEEJ_01819 2.44e-129 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase molybdenum cofactor assembly chaperone
HEHGKEEJ_01820 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HEHGKEEJ_01821 0.0 narZ 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HEHGKEEJ_01822 2.54e-243 moeB 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
HEHGKEEJ_01823 4.94e-109 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HEHGKEEJ_01824 1.27e-290 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 MoeA N-terminal region (domain I and II)
HEHGKEEJ_01825 1.17e-110 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HEHGKEEJ_01826 2.03e-136 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HEHGKEEJ_01827 1.56e-60 - - - - - - - -
HEHGKEEJ_01828 5.31e-242 nreB 2.7.13.3 - F ko:K07683 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Sensor histidine kinase
HEHGKEEJ_01829 7.45e-150 nreC - - K ko:K07696 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 PFAM regulatory protein LuxR
HEHGKEEJ_01830 2.45e-26 - - - - - - - -
HEHGKEEJ_01831 2.71e-234 - - - - - - - -
HEHGKEEJ_01832 3.34e-213 - - - H - - - geranyltranstransferase activity
HEHGKEEJ_01833 5.25e-279 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 Transporter, major facilitator family protein
HEHGKEEJ_01834 4.04e-48 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 ThiS family
HEHGKEEJ_01835 3.25e-84 moaE 2.8.1.12 - H ko:K03635,ko:K21142 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 MoaE protein
HEHGKEEJ_01836 1.21e-99 - - - S - - - Flavodoxin
HEHGKEEJ_01837 4.18e-165 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HEHGKEEJ_01838 3.12e-176 fecE 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
HEHGKEEJ_01839 8.2e-224 fecB - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HEHGKEEJ_01840 1.65e-151 - - - L - - - PFAM Integrase catalytic region
HEHGKEEJ_01841 1.77e-93 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEHGKEEJ_01842 6.83e-101 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEHGKEEJ_01843 2.24e-200 - - - KT ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 YcbB domain
HEHGKEEJ_01844 9.21e-244 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HEHGKEEJ_01845 1.13e-220 arcC 2.7.2.2 - E ko:K00926 ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200 ko00000,ko00001,ko01000 Belongs to the carbamate kinase family
HEHGKEEJ_01846 1.92e-209 - - - EG - - - EamA-like transporter family
HEHGKEEJ_01847 1.04e-135 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HEHGKEEJ_01848 1.53e-71 - - - S - - - Cupredoxin-like domain
HEHGKEEJ_01849 2.2e-65 - - - S - - - Cupredoxin-like domain
HEHGKEEJ_01850 0.0 copA 3.6.3.3, 3.6.3.5, 3.6.3.54 - P ko:K01534,ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HEHGKEEJ_01851 1.69e-117 - - - - - - - -
HEHGKEEJ_01853 1.28e-75 - - - - - - - -
HEHGKEEJ_01854 1.05e-305 nhaP3 - - P ko:K03316 - ko00000 Sodium proton antiporter
HEHGKEEJ_01859 3.64e-83 - - - - - - - -
HEHGKEEJ_01861 5.15e-91 - - - - - - - -
HEHGKEEJ_01863 1.89e-13 - - - L - - - DnaD domain protein
HEHGKEEJ_01869 1.08e-06 - - - S - - - Helix-turn-helix domain
HEHGKEEJ_01870 5.09e-55 - - - S - - - Phage regulatory protein Rha (Phage_pRha)
HEHGKEEJ_01871 2.06e-44 - - - - - - - -
HEHGKEEJ_01872 6.69e-27 - - - S - - - Helix-turn-helix domain
HEHGKEEJ_01874 1.66e-167 int2 - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_01878 1.37e-86 - - - - - - - -
HEHGKEEJ_01880 1.77e-13 - - - L - - - DnaD domain protein
HEHGKEEJ_01886 2.16e-47 - - - V - - - NUMOD4 motif
HEHGKEEJ_01888 7.33e-57 - - - K - - - COG3617 Prophage antirepressor
HEHGKEEJ_01889 1.39e-34 - - - - - - - -
HEHGKEEJ_01890 5.51e-26 - - - S - - - Helix-turn-helix domain
HEHGKEEJ_01891 1.55e-11 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HEHGKEEJ_01892 7.51e-171 int2 - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_01893 7.41e-130 - - - - - - - -
HEHGKEEJ_01894 1.25e-119 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HEHGKEEJ_01895 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HEHGKEEJ_01896 5.01e-200 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HEHGKEEJ_01897 2.39e-226 rnz 3.1.26.11 - J ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HEHGKEEJ_01898 0.0 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HEHGKEEJ_01899 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HEHGKEEJ_01900 2.44e-20 - - - - - - - -
HEHGKEEJ_01901 9.54e-241 ldhA 1.1.1.28 - C ko:K03778,ko:K18347 ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01504 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HEHGKEEJ_01902 0.0 ycfI - - V ko:K06147 - ko00000,ko02000 ABC transporter, ATP-binding protein
HEHGKEEJ_01903 0.0 yfiC - - V ko:K06147 - ko00000,ko02000 ABC transporter
HEHGKEEJ_01904 0.0 pepD2 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEHGKEEJ_01905 4.73e-113 ebsC - - J ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HEHGKEEJ_01906 6.1e-171 gntR - - K - - - UbiC transcription regulator-associated domain protein
HEHGKEEJ_01907 2.53e-83 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HEHGKEEJ_01908 4.81e-36 - - - I - - - transferase activity, transferring acyl groups other than amino-acyl groups
HEHGKEEJ_01909 0.0 xfp 4.1.2.22, 4.1.2.9 - G ko:K01621 ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120 ko00000,ko00001,ko01000 Phosphoketolase
HEHGKEEJ_01910 3.37e-307 - - - E - - - amino acid
HEHGKEEJ_01911 4.31e-178 yfhR3 - - S ko:K06889 - ko00000 Serine hydrolase (FSH1)
HEHGKEEJ_01912 6.57e-309 brnQ - - U ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HEHGKEEJ_01913 4.91e-210 - - - GK - - - ROK family
HEHGKEEJ_01914 0.0 fusA1 - - J - - - elongation factor G
HEHGKEEJ_01915 7.46e-106 uspA3 - - T - - - universal stress protein
HEHGKEEJ_01916 1.42e-248 lplA 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HEHGKEEJ_01917 5.44e-297 - - - L - - - transposase IS116 IS110 IS902 family protein
HEHGKEEJ_01918 0.0 potE - - E - - - Amino Acid
HEHGKEEJ_01919 0.0 arcD - - E ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HEHGKEEJ_01920 1.33e-278 arcT - - E - - - Aminotransferase
HEHGKEEJ_01921 4.96e-216 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine Aminopeptidase
HEHGKEEJ_01922 1.58e-101 ykuP - - C ko:K03839 - ko00000 Flavodoxin
HEHGKEEJ_01923 1.21e-88 gtcA - - S - - - Teichoic acid glycosylation protein
HEHGKEEJ_01924 8.2e-72 - - - - - - - -
HEHGKEEJ_01925 3.32e-263 mnaA 5.1.3.14 - G ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HEHGKEEJ_01927 2.32e-298 yfmL - - L - - - DEAD DEAH box helicase
HEHGKEEJ_01928 2.54e-243 mocA - - S - - - Oxidoreductase
HEHGKEEJ_01929 1.88e-80 - - - S - - - Domain of unknown function (DUF4828)
HEHGKEEJ_01930 1.46e-135 - 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HEHGKEEJ_01931 1.25e-211 - 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HEHGKEEJ_01932 0.0 gshA 6.3.2.2 - H ko:K01919 ko00270,ko00480,ko01100,map00270,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the glutamate--cysteine ligase type 1 family
HEHGKEEJ_01933 3.21e-247 - - - S - - - Protein of unknown function (DUF3114)
HEHGKEEJ_01934 4.36e-103 yjcF 3.5.4.33, 4.4.1.8 - K ko:K02348,ko:K07000,ko:K11991,ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007,ko03016 protein acetylation
HEHGKEEJ_01935 1.71e-148 ybhL - - S ko:K06890 - ko00000 Belongs to the BI1 family
HEHGKEEJ_01936 6.27e-94 - - - P - - - Major Facilitator Superfamily
HEHGKEEJ_01938 2.49e-43 xylB 2.7.1.17, 2.7.1.53 - G ko:K00854,ko:K00880 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the FGGY kinase family
HEHGKEEJ_01940 2.69e-36 - - - - - - - -
HEHGKEEJ_01941 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HEHGKEEJ_01942 2.09e-154 maa3 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HEHGKEEJ_01943 7.78e-200 - - - U ko:K05340 - ko00000,ko02000 sugar transport
HEHGKEEJ_01944 0.0 yclK - - T - - - Histidine kinase
HEHGKEEJ_01945 5.91e-176 yclJ - - K ko:K02483 - ko00000,ko02022 response regulator
HEHGKEEJ_01947 2.2e-110 lytE - - M - - - Lysin motif
HEHGKEEJ_01948 4.88e-194 - - - S - - - Cof-like hydrolase
HEHGKEEJ_01949 7.53e-104 - - - K - - - Transcriptional regulator
HEHGKEEJ_01950 0.0 oatA - - I - - - Acyltransferase
HEHGKEEJ_01951 5.17e-70 - - - - - - - -
HEHGKEEJ_01952 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HEHGKEEJ_01953 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HEHGKEEJ_01954 1.99e-165 ybbR - - S - - - YbbR-like protein
HEHGKEEJ_01955 6.61e-195 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HEHGKEEJ_01956 0.0 fucP - - G ko:K02429 - ko00000,ko02000 Major Facilitator Superfamily
HEHGKEEJ_01957 2.47e-88 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HEHGKEEJ_01958 5.54e-208 frc 2.8.3.16 - C ko:K07749 - ko00000,ko01000 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HEHGKEEJ_01959 0.0 spxB 1.2.3.3, 1.2.5.1, 2.2.1.6, 4.1.1.8 - EH ko:K00156,ko:K00158,ko:K01577,ko:K01652 ko00290,ko00620,ko00630,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00620,map00630,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HEHGKEEJ_01960 5.06e-182 - - - S ko:K09861 - ko00000 Belongs to the UPF0246 family
HEHGKEEJ_01961 4.16e-180 - - - S - - - Membrane
HEHGKEEJ_01962 2e-98 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase
HEHGKEEJ_01963 1.14e-27 - - - - - - - -
HEHGKEEJ_01964 3.65e-114 XK27_05190 - - S - - - Protein of unknown function (DUF1694)
HEHGKEEJ_01965 4.83e-312 rarA - - L ko:K07478 - ko00000 recombination factor protein RarA
HEHGKEEJ_01966 3.61e-61 - - - - - - - -
HEHGKEEJ_01967 1.95e-109 uspA - - T - - - universal stress protein
HEHGKEEJ_01968 1.3e-265 araR - - K ko:K02103 - ko00000,ko03000 Transcriptional regulator
HEHGKEEJ_01969 3.07e-203 yvgN - - S - - - Aldo keto reductase
HEHGKEEJ_01970 6.55e-137 maa 2.3.1.79 - S ko:K00661 - ko00000,ko01000 Maltose O-acetyltransferase
HEHGKEEJ_01971 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HEHGKEEJ_01972 9.45e-179 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HEHGKEEJ_01973 0.0 araB 2.7.1.16 - G ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 carbohydrate kinase FGGY
HEHGKEEJ_01974 0.0 araP - - U - - - Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HEHGKEEJ_01975 6.61e-194 - - - K - - - Helix-turn-helix XRE-family like proteins
HEHGKEEJ_01976 1.49e-309 - - - EGP - - - MFS transporter, metabolite H symporter (MHS) family protein
HEHGKEEJ_01977 1.89e-171 - - - IQ - - - dehydrogenase reductase
HEHGKEEJ_01978 2.33e-51 - - - - - - - -
HEHGKEEJ_01979 1.39e-149 - - - S ko:K07118 - ko00000 NAD(P)H-binding
HEHGKEEJ_01980 2.3e-52 - - - S - - - Cytochrome b5-like Heme/Steroid binding domain
HEHGKEEJ_01981 0.0 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEHGKEEJ_01982 9.76e-233 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HEHGKEEJ_01984 2.5e-132 - - - S ko:K07002 - ko00000 Serine hydrolase
HEHGKEEJ_01985 1.26e-82 psiE - - S ko:K13256 - ko00000 Phosphate-starvation-inducible E
HEHGKEEJ_01986 6.12e-182 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HEHGKEEJ_01988 3.04e-233 ydhF - - S - - - Aldo keto reductase
HEHGKEEJ_01989 3.6e-107 - 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 PAP2 superfamily
HEHGKEEJ_01990 0.0 - - - L - - - Helicase C-terminal domain protein
HEHGKEEJ_01992 0.0 - 1.8.1.7 - C ko:K00383,ko:K21739 ko00480,ko04918,map00480,map04918 ko00000,ko00001,ko01000 Pyridine nucleotide-disulfide oxidoreductase
HEHGKEEJ_01993 1.4e-73 - - - S - - - Sugar efflux transporter for intercellular exchange
HEHGKEEJ_01994 9.01e-164 - - - - - - - -
HEHGKEEJ_01995 3e-167 XK27_08875 - - O - - - PFAM peptidase M10A and M12B, matrixin and adamalysin
HEHGKEEJ_01996 5.73e-70 - - - EGP - - - Major Facilitator
HEHGKEEJ_01997 4.66e-106 - - - EGP - - - Major Facilitator
HEHGKEEJ_01998 6.75e-164 - - - M - - - Lysin motif
HEHGKEEJ_01999 5.69e-105 - - - - - - - -
HEHGKEEJ_02000 2.42e-122 - - - K - - - PFAM GCN5-related N-acetyltransferase
HEHGKEEJ_02001 7.98e-114 ltrA - - S - - - Bacterial low temperature requirement A protein (LtrA)
HEHGKEEJ_02002 3.69e-259 thiP - - U - - - Belongs to the purine-cytosine permease (2.A.39) family
HEHGKEEJ_02003 3.7e-19 - - - - - - - -
HEHGKEEJ_02004 1.26e-113 - - - S - - - Domain of unknown function (DUF4767)
HEHGKEEJ_02005 3.39e-254 - 1.1.1.1 - E ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 alcohol dehydrogenase
HEHGKEEJ_02006 2.26e-149 - - - S - - - Membrane
HEHGKEEJ_02007 1.1e-161 - - - O - - - Zinc-dependent metalloprotease
HEHGKEEJ_02008 3.82e-114 luxS 4.4.1.21 - H ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HEHGKEEJ_02009 2.51e-201 metQ1 - - P ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HEHGKEEJ_02011 7.01e-233 - - - S ko:K07035 - ko00000 Phosphotransferase system, EIIC
HEHGKEEJ_02012 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HEHGKEEJ_02013 2.96e-225 - - - - - - - -
HEHGKEEJ_02014 5.53e-52 ptpA 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HEHGKEEJ_02015 1.11e-263 - 1.1.1.90 - C ko:K00055 ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Zn-dependent alcohol dehydrogenases, class III
HEHGKEEJ_02018 3.73e-16 - - - L - - - helicase
HEHGKEEJ_02020 1.91e-09 - - - D - - - nuclear chromosome segregation
HEHGKEEJ_02022 4.68e-90 - - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HEHGKEEJ_02023 1.02e-278 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HEHGKEEJ_02032 6.84e-47 - - - L - - - Phage integrase, N-terminal SAM-like domain
HEHGKEEJ_02033 3.83e-153 - - - T - - - Putative diguanylate phosphodiesterase
HEHGKEEJ_02034 1.64e-252 - 2.7.7.65 - T ko:K02488 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko00002,ko01000,ko02022 GGDEF domain
HEHGKEEJ_02035 3.34e-107 - - - - - - - -
HEHGKEEJ_02036 0.0 yijG - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 Glycosyl transferase
HEHGKEEJ_02037 8.79e-107 - - - T - - - EAL domain
HEHGKEEJ_02038 9.34e-59 - - - T - - - EAL domain
HEHGKEEJ_02039 8.44e-168 - - - F - - - glutamine amidotransferase
HEHGKEEJ_02040 8.96e-79 - - - - - - - -
HEHGKEEJ_02041 7.75e-127 qorB 1.6.5.2 - GM ko:K19267 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 NmrA-like family
HEHGKEEJ_02042 9.48e-204 akr5f 1.1.1.346 - S ko:K06221 - ko00000,ko01000 reductase
HEHGKEEJ_02043 2.62e-184 - - - K - - - Transcriptional regulator
HEHGKEEJ_02044 2.82e-235 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase, type I
HEHGKEEJ_02045 1.45e-214 ypuA - - S - - - Protein of unknown function (DUF1002)
HEHGKEEJ_02046 1.17e-291 aadAT - - EK ko:K05825 ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210 ko00000,ko00001,ko01000 Aminotransferase, class I
HEHGKEEJ_02047 3.79e-222 hdhL 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily
HEHGKEEJ_02048 1.2e-195 mhpD - - Q ko:K02509 ko00350,ko01120,map00350,map01120 ko00000,ko00001,ko01000 hydratase
HEHGKEEJ_02049 8.13e-182 - - - S - - - Alpha beta hydrolase
HEHGKEEJ_02050 1.64e-105 - 2.3.1.79 - S ko:K00661 - ko00000,ko01000 transferase hexapeptide repeat
HEHGKEEJ_02051 1.48e-72 lysR - - K - - - Transcriptional regulator
HEHGKEEJ_02052 6.09e-162 phoU - - P ko:K02039 - ko00000 Plays a role in the regulation of phosphate uptake
HEHGKEEJ_02053 3.14e-177 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HEHGKEEJ_02054 2.7e-199 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease protein PstA
HEHGKEEJ_02055 1.95e-195 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HEHGKEEJ_02056 1.71e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HEHGKEEJ_02057 2.8e-168 - - - K ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C-terminal domain protein
HEHGKEEJ_02058 9.42e-174 - - - P ko:K02006 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HEHGKEEJ_02059 4.06e-184 - - - P ko:K02008 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HEHGKEEJ_02060 2.33e-238 cbiM - - P ko:K02007 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 PDGLE domain
HEHGKEEJ_02061 4.2e-96 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEHGKEEJ_02062 2e-56 - - - U - - - Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HEHGKEEJ_02063 9.18e-207 ureD - - O ko:K03190 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HEHGKEEJ_02064 1.4e-145 ureG - - KO ko:K03189 - ko00000 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HEHGKEEJ_02065 4.15e-170 ureF - - O ko:K03188 - ko00000 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HEHGKEEJ_02066 3.08e-102 ureE - - O ko:K03187 - ko00000 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HEHGKEEJ_02067 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Amidohydrolase family
HEHGKEEJ_02068 1.15e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease beta subunit
HEHGKEEJ_02069 8.76e-63 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Urease, gamma subunit
HEHGKEEJ_02070 3.59e-128 - - - S - - - AmiS/UreI family transporter
HEHGKEEJ_02071 1.31e-286 amt - - P ko:K03320 - ko00000,ko02000 ammonium transporter
HEHGKEEJ_02072 5.21e-56 - - - S - - - Glycosyltransferase family 28 C-terminal domain
HEHGKEEJ_02073 5.7e-95 - - - M - - - Oligosaccharide biosynthesis protein Alg14 like
HEHGKEEJ_02074 3.88e-132 rfbP - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 Bacterial sugar transferase
HEHGKEEJ_02075 3.55e-157 ywqD - - D - - - Capsular exopolysaccharide family
HEHGKEEJ_02076 3.76e-189 epsB - - M - - - biosynthesis protein
HEHGKEEJ_02077 1.65e-220 brpA - - K - - - Cell envelope-like function transcriptional attenuator common domain protein
HEHGKEEJ_02078 1.64e-13 - - - K - - - Transcriptional regulator, HxlR family
HEHGKEEJ_02079 3.82e-47 - - - - - - - -
HEHGKEEJ_02080 1.36e-116 - - - - - - - -
HEHGKEEJ_02081 0.0 glpK 2.7.1.30 - F ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HEHGKEEJ_02082 1.89e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Belongs to the 4-oxalocrotonate tautomerase family
HEHGKEEJ_02083 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 TrkA C-terminal domain protein
HEHGKEEJ_02084 0.0 pepD4 - - E ko:K08659 - ko00000,ko01000,ko01002 Dipeptidase
HEHGKEEJ_02085 2.7e-18 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEHGKEEJ_02086 7.38e-224 tnp2 - - L - - - PFAM Transposase, IS204 IS1001 IS1096 IS1165
HEHGKEEJ_02087 0.0 - 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Thioredoxin domain
HEHGKEEJ_02088 5.4e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Peroxiredoxin
HEHGKEEJ_02089 4.78e-193 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HEHGKEEJ_02090 1.29e-156 sdhB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 Serine dehydratase beta chain
HEHGKEEJ_02091 2.76e-277 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HEHGKEEJ_02092 1.43e-247 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter NhaC
HEHGKEEJ_02093 3.53e-297 - - - E ko:K20265 ko02024,map02024 ko00000,ko00001,ko02000 Amino acid permease
HEHGKEEJ_02094 0.0 tdc 4.1.1.25 - E ko:K22330 ko00350,map00350 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
HEHGKEEJ_02095 1.41e-128 ywlG - - S - - - Belongs to the UPF0340 family
HEHGKEEJ_02096 1.51e-199 - - - J - - - Methyltransferase
HEHGKEEJ_02097 1.73e-287 oxlT - - P ko:K08177 - ko00000,ko02000 Major Facilitator Superfamily
HEHGKEEJ_02098 3.95e-291 - - - L - - - Belongs to the 'phage' integrase family
HEHGKEEJ_02099 4.53e-45 - - - S - - - Domain of unknown function (DUF3173)
HEHGKEEJ_02101 0.0 - - - - - - - -
HEHGKEEJ_02102 7.75e-164 - - - - - - - -
HEHGKEEJ_02103 3.65e-100 tnpR1 - - L - - - Resolvase, N terminal domain
HEHGKEEJ_02104 0.0 nrdD 1.1.98.6 - F ko:K21636 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Ribonucleoside-triphosphate reductase
HEHGKEEJ_02105 1.37e-144 nrdG 1.97.1.4 - O ko:K04068 - ko00000,ko01000 Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HEHGKEEJ_02106 1.86e-212 - - - O - - - Uncharacterized protein family (UPF0051)
HEHGKEEJ_02107 6.73e-149 - - - M - - - LysM domain protein
HEHGKEEJ_02108 0.0 - - - EP - - - Psort location Cytoplasmic, score
HEHGKEEJ_02109 4.57e-137 - - - M - - - LysM domain protein
HEHGKEEJ_02110 2.83e-190 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HEHGKEEJ_02111 4.87e-299 - 1.3.1.1 - E ko:K17722 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HEHGKEEJ_02112 2.29e-309 - 1.3.1.1 - C ko:K17723 ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100 ko00000,ko00001,ko00002,ko01000 4Fe-4S dicluster domain
HEHGKEEJ_02113 2.42e-201 yeaE - - S - - - Aldo keto
HEHGKEEJ_02114 4.63e-101 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HEHGKEEJ_02115 0.0 umuC - - L ko:K03502 - ko00000,ko03400 impB/mucB/samB family C-terminal domain
HEHGKEEJ_02116 7.91e-104 - - - S - - - Psort location Cytoplasmic, score
HEHGKEEJ_02117 2.05e-110 - - - S - - - Short repeat of unknown function (DUF308)
HEHGKEEJ_02118 2.14e-82 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
HEHGKEEJ_02119 0.0 - - - L - - - PLD-like domain
HEHGKEEJ_02121 4.12e-227 rihA - - F ko:K01250 - ko00000,ko01000 Inosine-uridine preferring nucleoside hydrolase
HEHGKEEJ_02122 1.81e-146 - - - T ko:K10716 - ko00000,ko02000 Ion transport 2 domain protein
HEHGKEEJ_02123 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HEHGKEEJ_02124 2.07e-263 - - - G - - - Transporter, major facilitator family protein
HEHGKEEJ_02125 3.51e-142 yvrI - - K ko:K03091,ko:K03093 - ko00000,ko03021 sigma factor activity
HEHGKEEJ_02126 9.18e-83 yuxO - - Q - - - Thioesterase superfamily
HEHGKEEJ_02127 6.96e-201 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HEHGKEEJ_02128 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HEHGKEEJ_02129 0.0 feoB - - P ko:K04759 - ko00000,ko02000 transporter of a GTP-driven Fe(2 ) uptake system
HEHGKEEJ_02130 9.89e-43 feoA - - P ko:K04758 - ko00000,ko02000 FeoA domain

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)