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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
CMANEAJM_00003	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
CMANEAJM_00015	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
CMANEAJM_00016	5.46e-238	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
CMANEAJM_00017	1.25e-124	-	-	-	-	-	-	-	-
CMANEAJM_00018	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_00019	2.52e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
CMANEAJM_00021	6.28e-291	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMANEAJM_00022	2.95e-239	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
CMANEAJM_00023	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
CMANEAJM_00024	3.21e-215	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
CMANEAJM_00025	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_00026	5.79e-158	-	-	-	-	-	-	-	-
CMANEAJM_00027	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMANEAJM_00028	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_00029	1.27e-223	-	-	-	N	-	-	-	Cell shape-determining protein MreB
CMANEAJM_00030	3.13e-61	-	-	-	N	-	-	-	Cell shape-determining protein MreB
CMANEAJM_00032	6.56e-22	-	-	-	N	-	-	-	Cell shape-determining protein MreB
CMANEAJM_00033	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
CMANEAJM_00034	3.52e-20	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_00035	2.56e-313	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_00036	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_00037	9.32e-40	-	-	-	-	-	-	-	-
CMANEAJM_00038	2.91e-120	mraW1	-	-	J	-	-	-	Putative rRNA methylase
CMANEAJM_00039	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
CMANEAJM_00040	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
CMANEAJM_00041	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CMANEAJM_00042	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CMANEAJM_00043	5.24e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMANEAJM_00044	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
CMANEAJM_00045	8.79e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CMANEAJM_00046	4.15e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
CMANEAJM_00047	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMANEAJM_00048	1.69e-190	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_00049	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMANEAJM_00050	6.36e-161	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
CMANEAJM_00051	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CMANEAJM_00052	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMANEAJM_00053	4.04e-253	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
CMANEAJM_00054	7.07e-43	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
CMANEAJM_00056	1.16e-160	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
CMANEAJM_00057	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_00058	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
CMANEAJM_00059	5.59e-61	-	-	-	K	-	-	-	HTH domain
CMANEAJM_00060	2.16e-41	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CMANEAJM_00061	0.00062	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
CMANEAJM_00062	1.08e-79	-	-	-	S	-	-	-	Thymidylate synthase
CMANEAJM_00063	1.04e-33	rmeB	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_00064	1.33e-127	-	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
CMANEAJM_00065	5.72e-197	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMANEAJM_00066	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_00067	1.39e-134	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_00068	6.92e-55	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CMANEAJM_00069	1.02e-106	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CMANEAJM_00070	8.04e-191	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMANEAJM_00071	7.83e-140	-	-	-	-	-	-	-	-
CMANEAJM_00072	2.44e-283	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CMANEAJM_00073	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CMANEAJM_00074	5.37e-74	-	-	-	-	-	-	-	-
CMANEAJM_00075	7.58e-77	-	-	-	-	-	-	-	-
CMANEAJM_00076	2.49e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_00077	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_00078	8.82e-119	-	-	-	-	-	-	-	-
CMANEAJM_00079	7.12e-62	-	-	-	-	-	-	-	-
CMANEAJM_00080	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
CMANEAJM_00081	1.41e-82	uvrA2	-	-	L	-	-	-	ABC transporter
CMANEAJM_00084	4.29e-87	-	-	-	-	-	-	-	-
CMANEAJM_00085	9.03e-16	-	-	-	-	-	-	-	-
CMANEAJM_00086	3.89e-237	-	-	-	-	-	-	-	-
CMANEAJM_00087	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
CMANEAJM_00088	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
CMANEAJM_00089	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CMANEAJM_00090	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CMANEAJM_00091	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
CMANEAJM_00092	1.04e-291	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
CMANEAJM_00093	5.29e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
CMANEAJM_00094	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_00095	1.13e-48	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_00096	4.85e-33	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
CMANEAJM_00097	3.09e-125	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
CMANEAJM_00098	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
CMANEAJM_00099	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
CMANEAJM_00100	5.1e-97	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_00101	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_00102	3.59e-315	dinF	-	-	V	-	-	-	MatE
CMANEAJM_00103	1.79e-42	-	-	-	-	-	-	-	-
CMANEAJM_00106	9.97e-103	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
CMANEAJM_00107	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
CMANEAJM_00108	2.91e-109	-	-	-	-	-	-	-	-
CMANEAJM_00109	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CMANEAJM_00110	6.25e-138	-	-	-	-	-	-	-	-
CMANEAJM_00111	0.0	celR	-	-	K	-	-	-	PRD domain
CMANEAJM_00112	3.03e-117	celR	-	-	K	-	-	-	PRD domain
CMANEAJM_00113	5.44e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
CMANEAJM_00114	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMANEAJM_00115	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_00116	3.06e-86	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_00117	1.48e-172	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_00118	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_00119	1.28e-273	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
CMANEAJM_00120	1.41e-147	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CMANEAJM_00121	6.73e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMANEAJM_00122	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
CMANEAJM_00123	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
CMANEAJM_00124	2.77e-271	arcT	-	-	E	-	-	-	Aminotransferase
CMANEAJM_00125	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CMANEAJM_00126	2.43e-18	-	-	-	-	-	-	-	-
CMANEAJM_00127	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
CMANEAJM_00128	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
CMANEAJM_00129	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
CMANEAJM_00130	0.0	yhaN	-	-	L	-	-	-	AAA domain
CMANEAJM_00131	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMANEAJM_00132	6.35e-274	-	-	-	-	-	-	-	-
CMANEAJM_00133	2.81e-232	-	-	-	M	-	-	-	Peptidase family S41
CMANEAJM_00134	1.28e-138	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_00135	6.26e-76	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_00136	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CMANEAJM_00137	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CMANEAJM_00138	4.43e-129	-	-	-	-	-	-	-	-
CMANEAJM_00139	4.08e-101	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
CMANEAJM_00140	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
CMANEAJM_00141	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMANEAJM_00142	0.0	-	-	-	S	-	-	-	membrane
CMANEAJM_00143	1.44e-28	-	-	-	S	-	-	-	membrane
CMANEAJM_00144	1.22e-217	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CMANEAJM_00145	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
CMANEAJM_00146	2.55e-192	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CMANEAJM_00147	1.45e-65	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
CMANEAJM_00148	1.05e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CMANEAJM_00149	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
CMANEAJM_00150	2.15e-108	-	-	-	-	-	-	-	-
CMANEAJM_00151	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
CMANEAJM_00152	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_00153	3.5e-307	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
CMANEAJM_00154	0.0	-	-	-	-	-	-	-	-
CMANEAJM_00155	1.65e-80	-	-	-	-	-	-	-	-
CMANEAJM_00156	2.37e-198	-	-	-	S	-	-	-	Fn3-like domain
CMANEAJM_00157	1.15e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_00158	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_00159	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMANEAJM_00160	6.76e-73	-	-	-	-	-	-	-	-
CMANEAJM_00161	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
CMANEAJM_00162	1.1e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00163	1.92e-283	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_00164	4.08e-12	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
CMANEAJM_00165	2.14e-159	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
CMANEAJM_00166	2.8e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMANEAJM_00167	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
CMANEAJM_00168	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMANEAJM_00169	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CMANEAJM_00170	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
CMANEAJM_00171	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
CMANEAJM_00172	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
CMANEAJM_00173	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
CMANEAJM_00174	7.96e-163	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
CMANEAJM_00175	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
CMANEAJM_00176	5.48e-300	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CMANEAJM_00177	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
CMANEAJM_00178	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
CMANEAJM_00179	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CMANEAJM_00180	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
CMANEAJM_00181	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
CMANEAJM_00182	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMANEAJM_00183	2.63e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMANEAJM_00184	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMANEAJM_00185	1.59e-116	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMANEAJM_00186	9.31e-233	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
CMANEAJM_00187	1.39e-63	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
CMANEAJM_00188	6.05e-221	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
CMANEAJM_00189	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMANEAJM_00190	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMANEAJM_00191	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
CMANEAJM_00192	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMANEAJM_00193	9.27e-73	-	-	-	-	-	-	-	-
CMANEAJM_00194	6.02e-308	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
CMANEAJM_00195	1.49e-253	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
CMANEAJM_00196	1.35e-82	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CMANEAJM_00197	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CMANEAJM_00198	1.9e-315	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
CMANEAJM_00199	6.32e-114	-	-	-	-	-	-	-	-
CMANEAJM_00200	5.7e-127	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
CMANEAJM_00201	2.1e-228	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
CMANEAJM_00202	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
CMANEAJM_00203	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMANEAJM_00204	1.16e-147	yqeK	-	-	H	-	-	-	Hydrolase, HD family
CMANEAJM_00205	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMANEAJM_00206	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
CMANEAJM_00207	1.24e-279	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
CMANEAJM_00208	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
CMANEAJM_00209	8.76e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
CMANEAJM_00210	3.79e-224	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMANEAJM_00211	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMANEAJM_00212	5.74e-29	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CMANEAJM_00213	8.27e-248	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CMANEAJM_00214	1.38e-155	csrR	-	-	K	-	-	-	response regulator
CMANEAJM_00215	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMANEAJM_00216	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CMANEAJM_00217	1.07e-244	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
CMANEAJM_00218	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
CMANEAJM_00219	5.55e-288	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CMANEAJM_00220	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
CMANEAJM_00221	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMANEAJM_00222	1.54e-37	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
CMANEAJM_00223	1.82e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMANEAJM_00224	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMANEAJM_00225	1.09e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CMANEAJM_00226	7.16e-08	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMANEAJM_00227	2.03e-223	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMANEAJM_00228	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMANEAJM_00229	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMANEAJM_00230	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
CMANEAJM_00231	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMANEAJM_00232	1.96e-145	-	-	-	S	-	-	-	membrane
CMANEAJM_00233	5.72e-99	-	-	-	K	-	-	-	LytTr DNA-binding domain
CMANEAJM_00234	6.12e-72	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
CMANEAJM_00235	0.0	-	-	-	S	-	-	-	membrane
CMANEAJM_00236	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CMANEAJM_00237	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CMANEAJM_00238	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMANEAJM_00239	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
CMANEAJM_00240	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
CMANEAJM_00241	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
CMANEAJM_00242	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
CMANEAJM_00243	6.68e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
CMANEAJM_00244	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
CMANEAJM_00245	5.25e-177	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
CMANEAJM_00246	2.59e-121	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMANEAJM_00247	6.31e-63	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMANEAJM_00248	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
CMANEAJM_00249	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
CMANEAJM_00250	1.77e-205	-	-	-	-	-	-	-	-
CMANEAJM_00251	1.34e-232	-	-	-	-	-	-	-	-
CMANEAJM_00252	3.55e-127	-	-	-	S	-	-	-	Protein conserved in bacteria
CMANEAJM_00253	1.87e-74	-	-	-	-	-	-	-	-
CMANEAJM_00254	2.97e-41	-	-	-	-	-	-	-	-
CMANEAJM_00257	9.81e-27	-	-	-	-	-	-	-	-
CMANEAJM_00258	1.35e-59	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00259	1.87e-40	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00260	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
CMANEAJM_00261	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
CMANEAJM_00262	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
CMANEAJM_00263	6.04e-249	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CMANEAJM_00264	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMANEAJM_00265	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
CMANEAJM_00266	9.43e-90	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMANEAJM_00267	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMANEAJM_00268	5.54e-14	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMANEAJM_00269	1.82e-273	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMANEAJM_00270	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMANEAJM_00271	2.09e-203	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMANEAJM_00272	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
CMANEAJM_00273	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
CMANEAJM_00274	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
CMANEAJM_00275	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00276	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_00277	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMANEAJM_00278	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMANEAJM_00279	8.28e-73	-	-	-	-	-	-	-	-
CMANEAJM_00280	6.96e-145	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
CMANEAJM_00281	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMANEAJM_00282	6.32e-277	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMANEAJM_00283	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMANEAJM_00284	3.07e-44	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMANEAJM_00285	3.51e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMANEAJM_00286	4.78e-293	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMANEAJM_00287	4.1e-08	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CMANEAJM_00288	7.35e-133	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
CMANEAJM_00289	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
CMANEAJM_00290	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMANEAJM_00291	5.46e-152	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
CMANEAJM_00292	1.84e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
CMANEAJM_00293	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
CMANEAJM_00294	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CMANEAJM_00295	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
CMANEAJM_00296	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMANEAJM_00297	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMANEAJM_00298	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMANEAJM_00299	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMANEAJM_00300	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
CMANEAJM_00301	1.16e-292	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMANEAJM_00302	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMANEAJM_00303	3.13e-299	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMANEAJM_00304	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
CMANEAJM_00305	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
CMANEAJM_00306	2.24e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMANEAJM_00307	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
CMANEAJM_00308	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMANEAJM_00309	6.21e-68	-	-	-	-	-	-	-	-
CMANEAJM_00310	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
CMANEAJM_00311	1.1e-112	-	-	-	-	-	-	-	-
CMANEAJM_00312	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMANEAJM_00313	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
CMANEAJM_00315	6e-65	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
CMANEAJM_00316	1.48e-92	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
CMANEAJM_00317	1.29e-144	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
CMANEAJM_00318	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
CMANEAJM_00319	1.42e-224	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CMANEAJM_00320	1.28e-160	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
CMANEAJM_00321	2.2e-133	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
CMANEAJM_00322	1.79e-287	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CMANEAJM_00323	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CMANEAJM_00324	1.57e-11	entB	-	-	Q	-	-	-	Isochorismatase family
CMANEAJM_00325	1.73e-92	entB	-	-	Q	-	-	-	Isochorismatase family
CMANEAJM_00326	1.06e-228	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
CMANEAJM_00327	8.04e-254	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CMANEAJM_00328	4.44e-79	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
CMANEAJM_00330	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_00331	8.07e-46	yneE	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00332	1.13e-159	yneE	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00333	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CMANEAJM_00334	2.3e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMANEAJM_00335	1.06e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMANEAJM_00336	1.41e-214	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
CMANEAJM_00337	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
CMANEAJM_00338	2.37e-185	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMANEAJM_00339	1.48e-46	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMANEAJM_00340	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CMANEAJM_00341	9.88e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
CMANEAJM_00342	5e-197	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CMANEAJM_00343	4.64e-115	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
CMANEAJM_00344	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMANEAJM_00345	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
CMANEAJM_00346	2.29e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
CMANEAJM_00347	3.47e-112	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
CMANEAJM_00348	3.64e-162	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
CMANEAJM_00349	2.79e-61	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_00350	1.95e-120	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_00351	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
CMANEAJM_00352	2.97e-244	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMANEAJM_00353	1.22e-120	-	-	-	K	-	-	-	transcriptional regulator
CMANEAJM_00354	0.0	-	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_00355	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
CMANEAJM_00356	6.38e-92	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
CMANEAJM_00362	8.58e-71	-	-	-	-	-	-	-	-
CMANEAJM_00363	2.02e-39	-	-	-	-	-	-	-	-
CMANEAJM_00364	3.49e-196	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CMANEAJM_00365	5.76e-146	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
CMANEAJM_00366	1.13e-59	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
CMANEAJM_00367	2.05e-55	-	-	-	-	-	-	-	-
CMANEAJM_00368	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
CMANEAJM_00369	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CMANEAJM_00370	3.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
CMANEAJM_00371	5.97e-210	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMANEAJM_00372	3.57e-47	-	-	-	-	-	-	-	-
CMANEAJM_00373	5.79e-21	-	-	-	-	-	-	-	-
CMANEAJM_00374	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
CMANEAJM_00375	4e-40	-	-	-	S	-	-	-	CsbD-like
CMANEAJM_00376	1.06e-53	-	-	-	-	-	-	-	-
CMANEAJM_00377	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMANEAJM_00378	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
CMANEAJM_00379	5.78e-174	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMANEAJM_00380	9.68e-132	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMANEAJM_00381	3.35e-91	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
CMANEAJM_00382	4.65e-101	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
CMANEAJM_00383	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
CMANEAJM_00384	1.52e-67	-	-	-	-	-	-	-	-
CMANEAJM_00385	1.09e-56	-	-	-	-	-	-	-	-
CMANEAJM_00386	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CMANEAJM_00387	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
CMANEAJM_00388	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CMANEAJM_00389	1.23e-239	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CMANEAJM_00390	2.18e-79	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
CMANEAJM_00391	8.88e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
CMANEAJM_00392	2.91e-23	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
CMANEAJM_00394	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CMANEAJM_00395	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CMANEAJM_00396	3.92e-246	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CMANEAJM_00397	2.47e-250	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMANEAJM_00398	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
CMANEAJM_00399	1.16e-70	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CMANEAJM_00400	1.56e-134	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
CMANEAJM_00401	8.53e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
CMANEAJM_00402	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
CMANEAJM_00403	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
CMANEAJM_00404	2.55e-288	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
CMANEAJM_00405	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
CMANEAJM_00406	1.13e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
CMANEAJM_00407	7.74e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMANEAJM_00408	1.41e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_00409	1.84e-202	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CMANEAJM_00410	7.56e-109	-	-	-	T	-	-	-	Universal stress protein family
CMANEAJM_00411	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMANEAJM_00412	1.98e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMANEAJM_00413	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMANEAJM_00414	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
CMANEAJM_00415	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMANEAJM_00416	1.74e-141	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
CMANEAJM_00417	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMANEAJM_00419	7.35e-116	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CMANEAJM_00420	5.12e-148	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
CMANEAJM_00421	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_00422	1.31e-102	-	-	-	P	-	-	-	Major Facilitator Superfamily
CMANEAJM_00423	1.01e-64	-	-	-	P	-	-	-	Major Facilitator Superfamily
CMANEAJM_00424	1.28e-42	-	-	-	P	-	-	-	Major Facilitator Superfamily
CMANEAJM_00425	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
CMANEAJM_00426	5.38e-305	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
CMANEAJM_00427	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
CMANEAJM_00428	1.66e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_00429	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
CMANEAJM_00430	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
CMANEAJM_00431	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
CMANEAJM_00432	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMANEAJM_00433	1.86e-246	-	-	-	-	-	-	-	-
CMANEAJM_00434	3.69e-187	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
CMANEAJM_00435	1.32e-211	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
CMANEAJM_00436	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
CMANEAJM_00437	5.89e-81	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
CMANEAJM_00438	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
CMANEAJM_00439	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMANEAJM_00440	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMANEAJM_00441	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMANEAJM_00442	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
CMANEAJM_00443	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CMANEAJM_00444	0.0	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
CMANEAJM_00445	2.86e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
CMANEAJM_00446	2.6e-91	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
CMANEAJM_00448	1.11e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
CMANEAJM_00449	8.49e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
CMANEAJM_00450	1.19e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
CMANEAJM_00451	1.37e-119	-	-	-	F	-	-	-	NUDIX domain
CMANEAJM_00452	5.3e-209	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00453	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMANEAJM_00454	2.13e-266	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CMANEAJM_00455	5.61e-108	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
CMANEAJM_00457	3.43e-62	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00458	6.44e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
CMANEAJM_00459	2.03e-100	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
CMANEAJM_00460	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
CMANEAJM_00461	0.000375	-	-	-	-	-	-	-	-
CMANEAJM_00462	1.23e-63	-	-	-	-	-	-	-	-
CMANEAJM_00463	6.64e-189	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
CMANEAJM_00464	7.39e-241	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_00466	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
CMANEAJM_00467	2.98e-166	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
CMANEAJM_00468	2.59e-177	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
CMANEAJM_00469	1.23e-311	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CMANEAJM_00470	1.85e-174	-	-	-	-	-	-	-	-
CMANEAJM_00471	7.79e-78	-	-	-	-	-	-	-	-
CMANEAJM_00472	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
CMANEAJM_00473	5.54e-289	-	-	-	-	-	-	-	-
CMANEAJM_00474	7.15e-165	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
CMANEAJM_00475	2.97e-243	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
CMANEAJM_00476	6.77e-249	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMANEAJM_00477	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMANEAJM_00478	2.23e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMANEAJM_00479	1.6e-93	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_00480	1.31e-303	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CMANEAJM_00481	2.73e-58	-	-	-	-	-	-	-	-
CMANEAJM_00482	1.75e-312	-	-	-	M	-	-	-	Glycosyl transferase family group 2
CMANEAJM_00483	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMANEAJM_00484	2.19e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_00485	2.95e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
CMANEAJM_00487	1.95e-31	hol	-	-	S	-	-	-	COG5546 Small integral membrane protein
CMANEAJM_00488	2.54e-43	-	-	-	S	-	-	-	Haemolysin XhlA
CMANEAJM_00489	3.48e-225	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CMANEAJM_00490	4.28e-72	-	-	-	-	-	-	-	-
CMANEAJM_00493	0.0	-	-	-	S	-	-	-	Phage minor structural protein
CMANEAJM_00494	2.74e-289	-	-	-	S	-	-	-	Phage tail protein
CMANEAJM_00495	0.0	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
CMANEAJM_00496	5.6e-187	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
CMANEAJM_00497	5.43e-35	-	-	-	-	-	-	-	-
CMANEAJM_00498	4.36e-72	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
CMANEAJM_00499	1.24e-128	-	-	-	S	-	-	-	Phage tail tube protein
CMANEAJM_00500	6.4e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
CMANEAJM_00501	1.16e-88	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
CMANEAJM_00502	3.73e-71	-	-	-	S	-	-	-	Phage head-tail joining protein
CMANEAJM_00503	1.04e-38	-	-	-	-	-	-	-	-
CMANEAJM_00504	4.03e-97	-	-	-	S	-	-	-	Phage capsid family
CMANEAJM_00505	7.91e-169	-	-	-	S	-	-	-	Phage portal protein
CMANEAJM_00507	3.93e-282	-	-	-	S	-	-	-	Phage Terminase
CMANEAJM_00508	1.26e-27	-	-	-	L	-	-	-	Phage terminase, small subunit
CMANEAJM_00512	1.71e-15	-	-	-	-	-	-	-	-
CMANEAJM_00515	4.86e-17	-	-	-	S	-	-	-	HNH endonuclease
CMANEAJM_00518	2.28e-06	-	-	-	-	-	-	-	-
CMANEAJM_00519	1.26e-48	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMANEAJM_00520	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
CMANEAJM_00521	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMANEAJM_00522	1.22e-58	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
CMANEAJM_00523	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
CMANEAJM_00524	3.82e-228	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00525	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMANEAJM_00526	4.07e-153	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMANEAJM_00527	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMANEAJM_00528	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMANEAJM_00529	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
CMANEAJM_00530	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMANEAJM_00531	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMANEAJM_00532	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
CMANEAJM_00533	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMANEAJM_00534	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMANEAJM_00535	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
CMANEAJM_00536	5e-176	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMANEAJM_00537	5.31e-206	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMANEAJM_00539	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
CMANEAJM_00540	1.22e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
CMANEAJM_00541	2.46e-97	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
CMANEAJM_00542	2.46e-112	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
CMANEAJM_00543	4.12e-159	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CMANEAJM_00544	4.28e-253	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
CMANEAJM_00545	3.82e-242	qacA	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_00546	3.29e-67	qacA	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_00547	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
CMANEAJM_00548	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
CMANEAJM_00549	9.42e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
CMANEAJM_00550	8.39e-209	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
CMANEAJM_00551	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
CMANEAJM_00552	2.56e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMANEAJM_00553	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMANEAJM_00554	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00555	6.46e-109	-	-	-	-	-	-	-	-
CMANEAJM_00556	1.04e-290	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMANEAJM_00557	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMANEAJM_00558	1.29e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CMANEAJM_00559	4.1e-291	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
CMANEAJM_00560	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMANEAJM_00561	5.84e-279	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
CMANEAJM_00562	1.98e-281	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
CMANEAJM_00563	3.93e-109	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
CMANEAJM_00564	1.25e-39	-	-	-	M	-	-	-	Lysin motif
CMANEAJM_00565	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CMANEAJM_00566	6.63e-241	-	-	-	S	-	-	-	Helix-turn-helix domain
CMANEAJM_00567	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMANEAJM_00568	8.5e-66	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CMANEAJM_00569	5.24e-41	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
CMANEAJM_00570	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMANEAJM_00571	1.18e-174	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMANEAJM_00572	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMANEAJM_00573	2.4e-32	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CMANEAJM_00574	2.61e-165	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
CMANEAJM_00575	1.32e-216	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
CMANEAJM_00576	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
CMANEAJM_00577	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_00578	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
CMANEAJM_00579	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMANEAJM_00580	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
CMANEAJM_00581	7.03e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CMANEAJM_00582	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMANEAJM_00583	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
CMANEAJM_00584	1.88e-250	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMANEAJM_00585	2.51e-89	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CMANEAJM_00586	4.55e-61	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
CMANEAJM_00587	1.6e-291	-	-	-	M	-	-	-	O-Antigen ligase
CMANEAJM_00588	8.81e-166	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
CMANEAJM_00589	1.96e-207	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_00590	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_00591	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
CMANEAJM_00592	4.28e-52	-	-	-	P	-	-	-	Rhodanese Homology Domain
CMANEAJM_00593	7.43e-119	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_00594	1.37e-237	-	-	-	-	-	-	-	-
CMANEAJM_00595	5.21e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
CMANEAJM_00596	1.51e-232	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CMANEAJM_00597	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
CMANEAJM_00598	1.09e-310	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMANEAJM_00599	4.6e-307	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
CMANEAJM_00600	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00601	7.87e-266	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CMANEAJM_00602	0.0	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMANEAJM_00603	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
CMANEAJM_00604	1.25e-140	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
CMANEAJM_00605	1.08e-92	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
CMANEAJM_00606	1.52e-98	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_00607	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_00608	1.56e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
CMANEAJM_00609	2.82e-146	-	-	-	GM	-	-	-	epimerase
CMANEAJM_00610	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
CMANEAJM_00611	9.07e-158	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
CMANEAJM_00612	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CMANEAJM_00613	2.05e-166	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMANEAJM_00614	3.9e-208	-	-	-	S	-	-	-	Alpha beta hydrolase
CMANEAJM_00615	1.76e-146	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_00616	2.12e-102	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
CMANEAJM_00617	2.33e-206	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_00618	9.29e-222	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
CMANEAJM_00620	8.51e-161	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMANEAJM_00621	1.8e-157	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMANEAJM_00622	1.11e-134	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
CMANEAJM_00623	6.39e-260	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMANEAJM_00624	7.05e-172	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
CMANEAJM_00625	1.7e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_00627	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMANEAJM_00628	1.19e-102	-	-	-	K	-	-	-	MarR family
CMANEAJM_00629	1.49e-147	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
CMANEAJM_00630	1.77e-207	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00631	3.5e-169	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMANEAJM_00632	3.24e-90	-	-	-	-	-	-	-	-
CMANEAJM_00633	4.19e-144	-	-	-	-	-	-	-	-
CMANEAJM_00634	1.01e-253	-	-	-	-	-	-	-	-
CMANEAJM_00635	4.7e-211	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00636	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMANEAJM_00637	2.19e-284	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMANEAJM_00638	1.43e-118	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMANEAJM_00639	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CMANEAJM_00640	1.19e-34	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
CMANEAJM_00641	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
CMANEAJM_00642	8.14e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
CMANEAJM_00643	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMANEAJM_00644	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
CMANEAJM_00645	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMANEAJM_00646	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
CMANEAJM_00647	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
CMANEAJM_00648	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
CMANEAJM_00649	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMANEAJM_00650	3.38e-96	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
CMANEAJM_00651	2.72e-41	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
CMANEAJM_00652	7.36e-220	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CMANEAJM_00653	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMANEAJM_00654	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMANEAJM_00655	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMANEAJM_00656	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CMANEAJM_00657	4.09e-309	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
CMANEAJM_00658	2.83e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
CMANEAJM_00659	2.08e-21	-	-	-	G	-	-	-	Fructosamine kinase
CMANEAJM_00660	4.98e-180	-	-	-	G	-	-	-	Fructosamine kinase
CMANEAJM_00661	5.97e-151	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
CMANEAJM_00662	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMANEAJM_00663	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMANEAJM_00664	2.56e-76	-	-	-	-	-	-	-	-
CMANEAJM_00665	2.57e-171	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CMANEAJM_00666	8.31e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
CMANEAJM_00667	3.87e-148	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
CMANEAJM_00668	4.78e-65	-	-	-	-	-	-	-	-
CMANEAJM_00669	1.73e-67	-	-	-	-	-	-	-	-
CMANEAJM_00670	2.05e-133	-	-	-	L	ko:K07487	-	ko00000	Transposase
CMANEAJM_00671	3.23e-229	-	-	-	L	ko:K07487	-	ko00000	Transposase
CMANEAJM_00672	5.62e-41	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CMANEAJM_00673	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMANEAJM_00674	6.01e-280	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMANEAJM_00675	3.24e-18	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMANEAJM_00676	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMANEAJM_00677	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
CMANEAJM_00678	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMANEAJM_00679	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
CMANEAJM_00680	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
CMANEAJM_00681	1.47e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMANEAJM_00682	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
CMANEAJM_00683	2.24e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMANEAJM_00684	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMANEAJM_00685	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
CMANEAJM_00686	6.21e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CMANEAJM_00687	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMANEAJM_00688	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CMANEAJM_00689	1.72e-245	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
CMANEAJM_00690	5.94e-98	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CMANEAJM_00691	1.26e-177	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CMANEAJM_00692	3.52e-57	-	-	-	-	-	-	-	-
CMANEAJM_00693	4.47e-42	-	-	-	-	-	-	-	-
CMANEAJM_00694	1.05e-274	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CMANEAJM_00695	0.0	-	-	-	G	-	-	-	Major Facilitator
CMANEAJM_00696	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMANEAJM_00697	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMANEAJM_00698	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
CMANEAJM_00699	6.26e-57	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
CMANEAJM_00700	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
CMANEAJM_00701	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
CMANEAJM_00702	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMANEAJM_00703	3.42e-259	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMANEAJM_00704	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMANEAJM_00705	1.33e-293	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
CMANEAJM_00706	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
CMANEAJM_00707	1.46e-187	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMANEAJM_00708	1.72e-129	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
CMANEAJM_00709	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMANEAJM_00710	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
CMANEAJM_00711	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
CMANEAJM_00712	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMANEAJM_00713	9.79e-65	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
CMANEAJM_00714	2.46e-170	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
CMANEAJM_00715	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
CMANEAJM_00716	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
CMANEAJM_00717	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
CMANEAJM_00718	1.16e-28	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMANEAJM_00719	2.16e-55	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMANEAJM_00720	6.4e-122	-	-	-	-	-	-	-	-
CMANEAJM_00721	1.1e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
CMANEAJM_00722	2.75e-35	-	-	-	-	-	-	-	-
CMANEAJM_00723	3.81e-87	-	-	-	-	-	-	-	-
CMANEAJM_00724	6.58e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
CMANEAJM_00727	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_00728	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_00729	3.31e-22	-	-	-	S	-	-	-	Short C-terminal domain
CMANEAJM_00730	9.99e-05	-	-	-	S	-	-	-	Short C-terminal domain
CMANEAJM_00731	1.51e-53	-	-	-	L	-	-	-	HTH-like domain
CMANEAJM_00732	3.53e-43	-	-	-	L	ko:K07483	-	ko00000	transposase activity
CMANEAJM_00733	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_00734	8.56e-74	-	-	-	S	-	-	-	Phage integrase family
CMANEAJM_00737	1.75e-43	-	-	-	-	-	-	-	-
CMANEAJM_00738	3.06e-36	-	-	-	Q	-	-	-	Methyltransferase
CMANEAJM_00739	9.52e-94	-	-	-	Q	-	-	-	Methyltransferase
CMANEAJM_00740	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
CMANEAJM_00741	2.87e-270	-	-	-	EGP	-	-	-	Major facilitator Superfamily
CMANEAJM_00742	4.57e-135	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_00743	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMANEAJM_00744	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CMANEAJM_00745	2.33e-192	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
CMANEAJM_00746	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
CMANEAJM_00747	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_00748	4.83e-227	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMANEAJM_00749	1.29e-59	-	-	-	-	-	-	-	-
CMANEAJM_00750	8.98e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMANEAJM_00751	7.41e-134	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
CMANEAJM_00752	1.42e-120	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMANEAJM_00753	4.4e-82	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CMANEAJM_00754	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
CMANEAJM_00755	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
CMANEAJM_00756	2.54e-313	cps4J	-	-	S	-	-	-	MatE
CMANEAJM_00757	7.66e-225	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
CMANEAJM_00758	6.1e-294	-	-	-	-	-	-	-	-
CMANEAJM_00759	3.73e-192	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
CMANEAJM_00760	1.4e-259	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
CMANEAJM_00761	5.71e-165	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
CMANEAJM_00762	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
CMANEAJM_00763	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
CMANEAJM_00764	4.97e-157	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
CMANEAJM_00765	1.09e-33	epsB	-	-	M	-	-	-	biosynthesis protein
CMANEAJM_00766	1e-117	epsB	-	-	M	-	-	-	biosynthesis protein
CMANEAJM_00767	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMANEAJM_00768	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00769	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CMANEAJM_00770	5.12e-31	-	-	-	-	-	-	-	-
CMANEAJM_00771	3.75e-94	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CMANEAJM_00772	5.62e-41	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CMANEAJM_00773	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
CMANEAJM_00774	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
CMANEAJM_00775	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMANEAJM_00776	6.48e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMANEAJM_00777	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMANEAJM_00778	5.89e-204	-	-	-	S	-	-	-	Tetratricopeptide repeat
CMANEAJM_00779	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMANEAJM_00780	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMANEAJM_00781	3.84e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_00782	7.66e-250	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_00783	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMANEAJM_00784	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
CMANEAJM_00785	7.5e-174	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CMANEAJM_00786	3.21e-40	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
CMANEAJM_00787	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
CMANEAJM_00788	7.1e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
CMANEAJM_00789	1.27e-162	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
CMANEAJM_00790	4.98e-250	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
CMANEAJM_00791	2.99e-109	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMANEAJM_00792	4.98e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
CMANEAJM_00793	2.66e-55	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
CMANEAJM_00794	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CMANEAJM_00795	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
CMANEAJM_00796	2.95e-46	-	-	-	-	-	-	-	-
CMANEAJM_00797	1.3e-291	-	-	-	-	-	-	-	-
CMANEAJM_00798	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
CMANEAJM_00799	9.51e-135	-	-	-	-	-	-	-	-
CMANEAJM_00800	5.68e-243	-	-	-	-	-	-	-	-
CMANEAJM_00801	7.66e-250	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_00802	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CMANEAJM_00803	4.11e-72	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
CMANEAJM_00804	5e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
CMANEAJM_00805	6.24e-61	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
CMANEAJM_00806	1.24e-208	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
CMANEAJM_00807	5.45e-122	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
CMANEAJM_00808	7.52e-164	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
CMANEAJM_00809	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMANEAJM_00810	6.35e-230	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
CMANEAJM_00811	1.21e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
CMANEAJM_00812	2.29e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMANEAJM_00813	6.45e-111	-	-	-	-	-	-	-	-
CMANEAJM_00814	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
CMANEAJM_00815	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMANEAJM_00816	4.9e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
CMANEAJM_00817	2.16e-39	-	-	-	-	-	-	-	-
CMANEAJM_00818	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
CMANEAJM_00819	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMANEAJM_00820	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMANEAJM_00821	1.43e-11	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMANEAJM_00822	1.02e-155	-	-	-	S	-	-	-	repeat protein
CMANEAJM_00823	1.35e-53	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
CMANEAJM_00824	1.04e-86	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
CMANEAJM_00825	0.0	-	-	-	N	-	-	-	domain, Protein
CMANEAJM_00826	1.22e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
CMANEAJM_00827	1.19e-152	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_00828	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
CMANEAJM_00829	1.6e-110	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
CMANEAJM_00830	2.42e-183	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
CMANEAJM_00831	6.7e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMANEAJM_00832	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
CMANEAJM_00833	3.69e-278	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CMANEAJM_00834	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMANEAJM_00835	7.74e-47	-	-	-	-	-	-	-	-
CMANEAJM_00836	1.43e-124	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
CMANEAJM_00837	2e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMANEAJM_00838	5.12e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
CMANEAJM_00839	2.57e-47	-	-	-	K	-	-	-	LytTr DNA-binding domain
CMANEAJM_00840	1.47e-100	-	-	-	U	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
CMANEAJM_00841	7.04e-46	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
CMANEAJM_00842	2.8e-35	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	abc transporter atp-binding protein
CMANEAJM_00843	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMANEAJM_00844	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
CMANEAJM_00845	4.85e-186	ylmH	-	-	S	-	-	-	S4 domain protein
CMANEAJM_00846	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
CMANEAJM_00847	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMANEAJM_00848	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMANEAJM_00849	8.34e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMANEAJM_00850	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMANEAJM_00851	4.99e-79	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMANEAJM_00852	3.4e-114	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMANEAJM_00853	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMANEAJM_00854	5.67e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMANEAJM_00855	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
CMANEAJM_00856	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
CMANEAJM_00857	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMANEAJM_00858	7.24e-101	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
CMANEAJM_00859	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
CMANEAJM_00860	4.99e-224	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CMANEAJM_00861	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CMANEAJM_00862	3.71e-78	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
CMANEAJM_00863	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMANEAJM_00864	1.76e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
CMANEAJM_00865	1.46e-300	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CMANEAJM_00867	7.32e-119	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
CMANEAJM_00868	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMANEAJM_00869	3.87e-263	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
CMANEAJM_00870	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
CMANEAJM_00872	2.39e-176	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
CMANEAJM_00873	5.07e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
CMANEAJM_00874	2.35e-177	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMANEAJM_00875	7.58e-14	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMANEAJM_00876	2.61e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMANEAJM_00877	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CMANEAJM_00878	3.18e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
CMANEAJM_00879	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
CMANEAJM_00880	1.78e-120	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CMANEAJM_00881	4.9e-89	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CMANEAJM_00882	3.25e-17	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
CMANEAJM_00883	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CMANEAJM_00884	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMANEAJM_00885	3.83e-176	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
CMANEAJM_00886	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
CMANEAJM_00908	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
CMANEAJM_00909	1.11e-84	-	-	-	-	-	-	-	-
CMANEAJM_00910	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
CMANEAJM_00911	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMANEAJM_00912	7.18e-153	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
CMANEAJM_00913	2.18e-41	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CMANEAJM_00914	5.39e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
CMANEAJM_00915	4.82e-65	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMANEAJM_00916	5.15e-97	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMANEAJM_00917	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
CMANEAJM_00918	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CMANEAJM_00919	5.77e-151	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMANEAJM_00920	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CMANEAJM_00921	7.79e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMANEAJM_00922	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
CMANEAJM_00924	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
CMANEAJM_00925	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
CMANEAJM_00926	3.02e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
CMANEAJM_00927	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
CMANEAJM_00928	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
CMANEAJM_00929	1.55e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
CMANEAJM_00930	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMANEAJM_00931	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
CMANEAJM_00932	1.68e-40	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
CMANEAJM_00933	4.56e-210	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CMANEAJM_00934	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
CMANEAJM_00935	1.55e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
CMANEAJM_00936	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_00937	1.6e-96	-	-	-	-	-	-	-	-
CMANEAJM_00938	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CMANEAJM_00939	2.31e-202	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
CMANEAJM_00940	3.72e-178	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMANEAJM_00941	1.71e-94	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMANEAJM_00942	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMANEAJM_00943	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
CMANEAJM_00944	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
CMANEAJM_00945	2.32e-99	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMANEAJM_00946	8.74e-195	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
CMANEAJM_00947	2.17e-79	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CMANEAJM_00948	1.02e-60	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
CMANEAJM_00949	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CMANEAJM_00950	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMANEAJM_00951	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CMANEAJM_00952	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
CMANEAJM_00953	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMANEAJM_00954	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
CMANEAJM_00955	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMANEAJM_00956	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMANEAJM_00957	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
CMANEAJM_00958	2.9e-275	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMANEAJM_00959	1.32e-63	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CMANEAJM_00960	4.04e-288	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CMANEAJM_00961	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMANEAJM_00962	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMANEAJM_00963	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMANEAJM_00964	4.02e-114	-	-	-	-	-	-	-	-
CMANEAJM_00965	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
CMANEAJM_00966	1.35e-93	-	-	-	-	-	-	-	-
CMANEAJM_00967	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMANEAJM_00968	1.38e-100	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMANEAJM_00969	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMANEAJM_00970	4.51e-133	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMANEAJM_00971	4.34e-103	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
CMANEAJM_00972	2.79e-65	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
CMANEAJM_00973	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
CMANEAJM_00974	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMANEAJM_00975	9.01e-294	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
CMANEAJM_00976	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMANEAJM_00977	5.74e-172	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
CMANEAJM_00978	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
CMANEAJM_00979	1.21e-192	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CMANEAJM_00980	1.46e-83	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
CMANEAJM_00981	3.74e-302	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
CMANEAJM_00982	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
CMANEAJM_00983	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_00984	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
CMANEAJM_00985	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
CMANEAJM_00986	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CMANEAJM_00987	1.34e-114	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
CMANEAJM_00988	5.01e-181	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
CMANEAJM_00989	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
CMANEAJM_00990	5.48e-14	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CMANEAJM_00991	1.21e-114	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
CMANEAJM_00992	9.36e-317	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CMANEAJM_00993	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMANEAJM_00994	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMANEAJM_00995	1.91e-300	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
CMANEAJM_00996	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMANEAJM_00997	2.22e-278	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
CMANEAJM_00998	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMANEAJM_00999	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
CMANEAJM_01000	1.07e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMANEAJM_01001	1.15e-144	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
CMANEAJM_01002	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CMANEAJM_01003	1.57e-142	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
CMANEAJM_01004	2.63e-58	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_01005	8.68e-284	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
CMANEAJM_01006	3.43e-55	-	2.7.1.191	-	G	ko:K02793	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMANEAJM_01007	5.7e-119	-	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose fructose sorbose family IID component
CMANEAJM_01008	4.54e-132	-	-	-	G	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMANEAJM_01009	3.79e-85	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMANEAJM_01010	1.47e-103	-	-	-	K	-	-	-	Periplasmic binding proteins and sugar binding domain of LacI family
CMANEAJM_01011	4.39e-08	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein LacI transcriptional regulator
CMANEAJM_01012	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
CMANEAJM_01013	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
CMANEAJM_01014	1.34e-52	-	-	-	-	-	-	-	-
CMANEAJM_01015	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
CMANEAJM_01016	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CMANEAJM_01017	1.19e-175	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01018	3.41e-16	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01019	2.52e-235	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
CMANEAJM_01020	5.19e-110	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
CMANEAJM_01021	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
CMANEAJM_01022	2.16e-241	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
CMANEAJM_01023	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
CMANEAJM_01024	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CMANEAJM_01025	4.18e-165	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
CMANEAJM_01026	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_01027	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMANEAJM_01028	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
CMANEAJM_01029	8.96e-256	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
CMANEAJM_01030	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
CMANEAJM_01031	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
CMANEAJM_01032	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
CMANEAJM_01033	1.96e-131	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMANEAJM_01034	2.94e-315	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMANEAJM_01035	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
CMANEAJM_01036	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMANEAJM_01037	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMANEAJM_01038	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMANEAJM_01039	2.03e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMANEAJM_01040	5.41e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMANEAJM_01041	1.81e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMANEAJM_01042	4.82e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
CMANEAJM_01043	4.19e-192	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CMANEAJM_01044	2.51e-82	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
CMANEAJM_01045	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMANEAJM_01046	9.47e-120	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMANEAJM_01047	1.58e-128	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMANEAJM_01048	4.58e-19	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMANEAJM_01049	2.96e-242	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMANEAJM_01050	9.47e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMANEAJM_01051	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMANEAJM_01052	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
CMANEAJM_01053	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
CMANEAJM_01054	1.06e-174	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
CMANEAJM_01055	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
CMANEAJM_01056	1.08e-244	ampC	-	-	V	-	-	-	Beta-lactamase
CMANEAJM_01057	8.57e-41	-	-	-	-	-	-	-	-
CMANEAJM_01058	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
CMANEAJM_01059	1.33e-77	-	-	-	-	-	-	-	-
CMANEAJM_01060	5.37e-182	-	-	-	-	-	-	-	-
CMANEAJM_01061	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMANEAJM_01062	1.84e-24	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
CMANEAJM_01063	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01064	1.81e-85	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMANEAJM_01065	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
CMANEAJM_01067	1.98e-40	-	-	-	-	-	-	-	-
CMANEAJM_01070	1.52e-38	-	-	-	-	-	-	-	-
CMANEAJM_01071	9.37e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CMANEAJM_01074	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
CMANEAJM_01075	4.85e-257	-	-	-	S	-	-	-	Phage portal protein
CMANEAJM_01077	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
CMANEAJM_01078	2.22e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
CMANEAJM_01079	1.1e-90	-	-	-	L	ko:K07451	-	ko00000,ko01000,ko02048	Phage-associated protein
CMANEAJM_01080	4.41e-64	-	-	-	S	-	-	-	Head-tail joining protein
CMANEAJM_01082	3.14e-109	-	-	-	-	-	-	-	-
CMANEAJM_01083	2.49e-133	-	-	-	S	-	-	-	Virulence-associated protein E
CMANEAJM_01084	9.33e-129	-	-	-	S	-	-	-	Virulence-associated protein E
CMANEAJM_01085	7.05e-15	-	-	-	S	-	-	-	Virulence-associated protein E
CMANEAJM_01086	4.42e-85	-	-	-	L	-	-	-	DNA replication protein
CMANEAJM_01087	1.12e-72	-	-	-	L	-	-	-	DNA replication protein
CMANEAJM_01089	1.96e-13	-	-	-	-	-	-	-	-
CMANEAJM_01093	1.17e-271	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMANEAJM_01094	1.28e-51	-	-	-	-	-	-	-	-
CMANEAJM_01095	9.28e-58	-	-	-	-	-	-	-	-
CMANEAJM_01096	1.27e-109	-	-	-	K	-	-	-	MarR family
CMANEAJM_01097	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
CMANEAJM_01098	0.0	inlJ	-	-	M	-	-	-	MucBP domain
CMANEAJM_01099	6.58e-24	-	-	-	-	-	-	-	-
CMANEAJM_01100	3.26e-24	-	-	-	-	-	-	-	-
CMANEAJM_01101	1.56e-22	-	-	-	-	-	-	-	-
CMANEAJM_01102	1.07e-26	-	-	-	-	-	-	-	-
CMANEAJM_01103	9.35e-24	-	-	-	-	-	-	-	-
CMANEAJM_01104	9.35e-24	-	-	-	-	-	-	-	-
CMANEAJM_01105	9.35e-24	-	-	-	-	-	-	-	-
CMANEAJM_01106	2.16e-26	-	-	-	-	-	-	-	-
CMANEAJM_01107	4.63e-24	-	-	-	-	-	-	-	-
CMANEAJM_01108	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
CMANEAJM_01109	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_01110	2.04e-180	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01111	1.29e-200	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01112	3.13e-15	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01113	6.12e-32	-	-	-	-	-	-	-	-
CMANEAJM_01114	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
CMANEAJM_01115	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CMANEAJM_01116	1.06e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
CMANEAJM_01117	2.89e-254	yclK	-	-	T	-	-	-	Histidine kinase
CMANEAJM_01118	3e-63	yclK	-	-	T	-	-	-	Histidine kinase
CMANEAJM_01119	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
CMANEAJM_01120	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
CMANEAJM_01121	1.06e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
CMANEAJM_01122	1.26e-218	-	-	-	EG	-	-	-	EamA-like transporter family
CMANEAJM_01124	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
CMANEAJM_01125	1.31e-64	-	-	-	-	-	-	-	-
CMANEAJM_01126	4.55e-185	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
CMANEAJM_01127	1.93e-70	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
CMANEAJM_01128	1.63e-177	-	-	-	F	-	-	-	NUDIX domain
CMANEAJM_01129	9.56e-19	-	-	-	-	-	-	-	-
CMANEAJM_01131	2e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_01132	4.27e-223	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
CMANEAJM_01133	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
CMANEAJM_01134	2.29e-48	-	-	-	-	-	-	-	-
CMANEAJM_01135	1.11e-45	-	-	-	-	-	-	-	-
CMANEAJM_01136	2.58e-274	-	-	-	T	-	-	-	diguanylate cyclase
CMANEAJM_01137	5.24e-77	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_01138	2.43e-95	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_01139	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CMANEAJM_01140	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
CMANEAJM_01141	5.76e-107	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMANEAJM_01142	9.2e-62	-	-	-	-	-	-	-	-
CMANEAJM_01143	9.09e-263	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMANEAJM_01144	8.22e-178	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMANEAJM_01145	1.31e-242	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMANEAJM_01146	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CMANEAJM_01147	8.59e-196	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
CMANEAJM_01148	1.46e-80	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
CMANEAJM_01149	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
CMANEAJM_01150	4.22e-211	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
CMANEAJM_01151	2.79e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01152	6.03e-196	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMANEAJM_01153	2.7e-102	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01154	3.01e-57	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01155	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
CMANEAJM_01156	2.34e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
CMANEAJM_01157	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
CMANEAJM_01158	6.8e-123	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMANEAJM_01159	1.45e-86	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMANEAJM_01160	8.11e-81	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMANEAJM_01161	5.11e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
CMANEAJM_01162	2.49e-77	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CMANEAJM_01163	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CMANEAJM_01164	5.62e-165	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CMANEAJM_01165	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMANEAJM_01166	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
CMANEAJM_01167	3.86e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMANEAJM_01168	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CMANEAJM_01169	6.31e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CMANEAJM_01170	1.3e-207	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
CMANEAJM_01171	1.51e-282	ysaA	-	-	V	-	-	-	RDD family
CMANEAJM_01172	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
CMANEAJM_01173	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
CMANEAJM_01174	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
CMANEAJM_01175	2.05e-189	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_01176	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
CMANEAJM_01177	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMANEAJM_01178	4.89e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMANEAJM_01179	1.45e-46	-	-	-	-	-	-	-	-
CMANEAJM_01180	3.1e-144	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMANEAJM_01181	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CMANEAJM_01182	8.73e-148	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CMANEAJM_01183	2.55e-137	-	-	-	M	-	-	-	domain protein
CMANEAJM_01184	8.76e-212	-	-	-	M	-	-	-	domain protein
CMANEAJM_01185	7.35e-99	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_01186	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMANEAJM_01187	2.95e-19	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
CMANEAJM_01188	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
CMANEAJM_01189	3.85e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
CMANEAJM_01190	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_01191	1.85e-248	-	-	-	S	-	-	-	domain, Protein
CMANEAJM_01192	1.06e-76	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
CMANEAJM_01193	9.16e-110	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
CMANEAJM_01194	4.26e-127	-	-	-	C	-	-	-	Nitroreductase family
CMANEAJM_01195	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
CMANEAJM_01196	2.04e-188	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMANEAJM_01197	7.61e-154	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMANEAJM_01198	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
CMANEAJM_01199	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMANEAJM_01200	6.91e-96	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
CMANEAJM_01201	8.29e-117	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
CMANEAJM_01202	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
CMANEAJM_01203	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMANEAJM_01204	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMANEAJM_01205	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
CMANEAJM_01206	2.66e-172	-	-	-	-	-	-	-	-
CMANEAJM_01207	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01208	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
CMANEAJM_01209	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
CMANEAJM_01210	2.29e-151	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CMANEAJM_01211	1.67e-22	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CMANEAJM_01212	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
CMANEAJM_01213	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_01214	7.58e-210	-	-	-	-	-	-	-	-
CMANEAJM_01216	5.03e-75	-	-	-	-	-	-	-	-
CMANEAJM_01217	8.34e-65	-	-	-	-	-	-	-	-
CMANEAJM_01218	7.7e-160	-	-	-	L	ko:K07487	-	ko00000	Transposase
CMANEAJM_01219	1.46e-173	-	-	-	L	ko:K07487	-	ko00000	Transposase
CMANEAJM_01220	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMANEAJM_01221	1.17e-88	-	-	-	-	-	-	-	-
CMANEAJM_01222	1.19e-186	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
CMANEAJM_01223	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
CMANEAJM_01224	3.87e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
CMANEAJM_01225	4.74e-61	-	-	-	-	-	-	-	-
CMANEAJM_01226	1.57e-71	-	-	-	-	-	-	-	-
CMANEAJM_01227	2.82e-105	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
CMANEAJM_01228	4.05e-98	-	-	-	-	-	-	-	-
CMANEAJM_01229	5.54e-61	-	-	-	-	-	-	-	-
CMANEAJM_01230	4.26e-250	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
CMANEAJM_01231	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
CMANEAJM_01232	2.43e-95	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_01233	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_01234	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
CMANEAJM_01235	8.36e-202	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
CMANEAJM_01236	1.18e-24	-	-	-	-	-	-	-	-
CMANEAJM_01237	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
CMANEAJM_01238	9.66e-97	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
CMANEAJM_01239	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
CMANEAJM_01240	3.96e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
CMANEAJM_01241	1.85e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
CMANEAJM_01242	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CMANEAJM_01243	5.06e-56	-	-	-	S	-	-	-	Putative esterase
CMANEAJM_01244	6.37e-116	-	-	-	S	-	-	-	Putative esterase
CMANEAJM_01245	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_01246	4.75e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMANEAJM_01247	6.08e-179	-	-	-	-	-	-	-	-
CMANEAJM_01248	3.04e-154	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
CMANEAJM_01249	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
CMANEAJM_01250	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CMANEAJM_01251	5.4e-80	-	-	-	-	-	-	-	-
CMANEAJM_01252	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CMANEAJM_01253	2.97e-76	-	-	-	-	-	-	-	-
CMANEAJM_01254	4.82e-15	yhdP	-	-	S	-	-	-	Transporter associated domain
CMANEAJM_01255	8.76e-281	yhdP	-	-	S	-	-	-	Transporter associated domain
CMANEAJM_01256	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
CMANEAJM_01257	2.15e-25	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMANEAJM_01258	1.02e-303	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMANEAJM_01259	1.23e-234	yttB	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_01260	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_01261	2.19e-220	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CMANEAJM_01262	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
CMANEAJM_01263	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMANEAJM_01264	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
CMANEAJM_01265	1.19e-276	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CMANEAJM_01266	1.84e-204	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMANEAJM_01267	3.59e-26	-	-	-	-	-	-	-	-
CMANEAJM_01268	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMANEAJM_01269	2.69e-174	mleR	-	-	K	-	-	-	LysR family
CMANEAJM_01270	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01271	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
CMANEAJM_01272	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CMANEAJM_01273	1.08e-190	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
CMANEAJM_01274	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMANEAJM_01275	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
CMANEAJM_01276	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
CMANEAJM_01277	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMANEAJM_01278	1.09e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMANEAJM_01279	1.23e-157	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMANEAJM_01280	3.16e-17	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMANEAJM_01281	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CMANEAJM_01282	9.77e-42	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CMANEAJM_01283	1.81e-109	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CMANEAJM_01284	3.36e-272	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CMANEAJM_01285	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMANEAJM_01286	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
CMANEAJM_01287	1.27e-91	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMANEAJM_01288	1.23e-20	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMANEAJM_01289	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
CMANEAJM_01290	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
CMANEAJM_01291	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
CMANEAJM_01292	4.71e-208	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_01293	1.25e-199	-	-	-	T	-	-	-	EAL domain
CMANEAJM_01294	2.62e-121	-	-	-	-	-	-	-	-
CMANEAJM_01295	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
CMANEAJM_01296	4.79e-74	-	-	-	E	-	-	-	Methionine synthase
CMANEAJM_01297	3.48e-48	-	-	-	E	-	-	-	Methionine synthase
CMANEAJM_01298	2.71e-280	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
CMANEAJM_01299	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
CMANEAJM_01300	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMANEAJM_01301	2.9e-156	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CMANEAJM_01302	1.77e-16	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
CMANEAJM_01303	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMANEAJM_01304	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMANEAJM_01305	6.91e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMANEAJM_01306	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMANEAJM_01307	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
CMANEAJM_01308	1.94e-268	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMANEAJM_01309	3.1e-103	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMANEAJM_01310	1.01e-308	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
CMANEAJM_01311	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CMANEAJM_01312	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
CMANEAJM_01313	4.81e-188	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CMANEAJM_01314	5.95e-153	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
CMANEAJM_01315	9.78e-190	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_01316	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
CMANEAJM_01317	2.05e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01318	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
CMANEAJM_01319	4.76e-56	-	-	-	-	-	-	-	-
CMANEAJM_01320	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
CMANEAJM_01321	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01322	3.41e-190	-	-	-	-	-	-	-	-
CMANEAJM_01323	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
CMANEAJM_01324	1.48e-45	-	-	-	-	-	-	-	-
CMANEAJM_01325	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
CMANEAJM_01326	1.02e-113	-	-	-	-	-	-	-	-
CMANEAJM_01327	1.98e-65	-	-	-	-	-	-	-	-
CMANEAJM_01328	4.79e-13	-	-	-	-	-	-	-	-
CMANEAJM_01329	3.03e-299	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CMANEAJM_01330	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
CMANEAJM_01331	1.52e-151	-	-	-	-	-	-	-	-
CMANEAJM_01332	1.21e-69	-	-	-	-	-	-	-	-
CMANEAJM_01333	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CMANEAJM_01334	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
CMANEAJM_01335	4.65e-186	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMANEAJM_01336	2.96e-41	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
CMANEAJM_01337	1.44e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMANEAJM_01338	1.27e-129	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
CMANEAJM_01339	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
CMANEAJM_01340	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CMANEAJM_01341	6.56e-48	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
CMANEAJM_01342	1.42e-268	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
CMANEAJM_01343	1.48e-292	-	-	-	S	-	-	-	Sterol carrier protein domain
CMANEAJM_01344	5.78e-288	-	-	-	EGP	-	-	-	Transmembrane secretion effector
CMANEAJM_01345	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
CMANEAJM_01346	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMANEAJM_01347	8.66e-152	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_01348	3.28e-35	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01349	9.27e-81	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01350	8.39e-82	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01351	4.29e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMANEAJM_01352	1.91e-316	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
CMANEAJM_01353	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01354	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01355	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
CMANEAJM_01356	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_01357	1.83e-168	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
CMANEAJM_01358	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
CMANEAJM_01359	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
CMANEAJM_01360	7.63e-107	-	-	-	-	-	-	-	-
CMANEAJM_01361	5.06e-196	-	-	-	S	-	-	-	hydrolase
CMANEAJM_01362	2.5e-234	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMANEAJM_01363	2.8e-204	-	-	-	EG	-	-	-	EamA-like transporter family
CMANEAJM_01364	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CMANEAJM_01365	5.52e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CMANEAJM_01366	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
CMANEAJM_01367	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
CMANEAJM_01368	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
CMANEAJM_01369	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
CMANEAJM_01370	4.3e-44	-	-	-	-	-	-	-	-
CMANEAJM_01371	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
CMANEAJM_01372	3.24e-37	ycaM	-	-	E	-	-	-	amino acid
CMANEAJM_01373	1.02e-270	ycaM	-	-	E	-	-	-	amino acid
CMANEAJM_01374	1.41e-100	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CMANEAJM_01375	1.42e-212	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
CMANEAJM_01376	3.45e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CMANEAJM_01377	8.79e-208	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_01379	2.04e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
CMANEAJM_01380	5.04e-111	-	-	-	S	-	-	-	Pfam:DUF3816
CMANEAJM_01381	1.21e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMANEAJM_01382	1.27e-143	-	-	-	-	-	-	-	-
CMANEAJM_01383	1.32e-230	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CMANEAJM_01384	6.38e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
CMANEAJM_01385	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CMANEAJM_01386	3.38e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
CMANEAJM_01387	2.69e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_01388	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMANEAJM_01389	2.18e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
CMANEAJM_01390	1.2e-240	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CMANEAJM_01391	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01392	2.76e-117	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
CMANEAJM_01393	5.72e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
CMANEAJM_01394	1.02e-126	ywjB	-	-	H	-	-	-	RibD C-terminal domain
CMANEAJM_01395	1.14e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMANEAJM_01396	7.33e-115	-	-	-	S	-	-	-	Membrane
CMANEAJM_01397	2.11e-199	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CMANEAJM_01398	9.98e-256	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
CMANEAJM_01399	4.86e-56	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
CMANEAJM_01400	1.13e-256	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_01401	2.25e-104	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CMANEAJM_01402	8.98e-41	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CMANEAJM_01403	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CMANEAJM_01404	4.03e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CMANEAJM_01405	8.99e-133	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMANEAJM_01406	2.17e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
CMANEAJM_01407	2.4e-193	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_01408	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
CMANEAJM_01409	1.89e-286	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_01410	7.4e-20	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
CMANEAJM_01412	1.5e-79	-	-	-	M	-	-	-	LysM domain
CMANEAJM_01413	3.92e-120	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
CMANEAJM_01414	4.23e-215	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01415	2.26e-268	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
CMANEAJM_01416	2.92e-210	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_01417	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_01418	1.16e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
CMANEAJM_01419	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
CMANEAJM_01420	7.37e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
CMANEAJM_01421	1.3e-63	-	-	-	H	-	-	-	RibD C-terminal domain
CMANEAJM_01423	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
CMANEAJM_01424	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
CMANEAJM_01425	2.03e-155	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01427	2.93e-151	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMANEAJM_01428	5.27e-140	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMANEAJM_01429	2.44e-149	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CMANEAJM_01430	1.58e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CMANEAJM_01431	9.82e-111	-	-	-	-	-	-	-	-
CMANEAJM_01432	4.4e-112	yvbK	-	-	K	-	-	-	GNAT family
CMANEAJM_01433	2.8e-49	-	-	-	-	-	-	-	-
CMANEAJM_01434	2.81e-64	-	-	-	-	-	-	-	-
CMANEAJM_01435	2.22e-144	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
CMANEAJM_01436	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
CMANEAJM_01437	6.67e-204	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_01438	1.03e-133	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01439	2.89e-197	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
CMANEAJM_01440	2.9e-194	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
CMANEAJM_01441	8.11e-180	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CMANEAJM_01442	2.92e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMANEAJM_01443	2.47e-97	-	-	-	C	-	-	-	Flavodoxin
CMANEAJM_01444	1.04e-51	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
CMANEAJM_01445	5.93e-90	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	reductase
CMANEAJM_01446	1.07e-116	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
CMANEAJM_01447	1.83e-111	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01448	7.86e-138	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CMANEAJM_01449	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_01450	2.43e-95	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_01451	5.63e-98	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_01453	5.16e-32	-	-	-	C	-	-	-	Flavodoxin
CMANEAJM_01454	2e-27	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_01455	8.57e-148	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_01456	4.86e-165	-	-	-	C	-	-	-	Aldo keto reductase
CMANEAJM_01457	1.28e-177	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CMANEAJM_01458	3.29e-165	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
CMANEAJM_01459	2.19e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_01461	1.46e-75	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01462	2.39e-20	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01463	1.78e-137	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
CMANEAJM_01464	4.21e-56	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
CMANEAJM_01465	8.65e-30	-	-	-	K	ko:K20373	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
CMANEAJM_01466	2.21e-46	-	-	-	-	-	-	-	-
CMANEAJM_01467	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
CMANEAJM_01468	1.04e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CMANEAJM_01469	7.47e-164	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
CMANEAJM_01470	1.03e-40	-	-	-	-	-	-	-	-
CMANEAJM_01471	9.15e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
CMANEAJM_01472	7.27e-287	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
CMANEAJM_01473	1.86e-132	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
CMANEAJM_01474	1.48e-248	-	-	-	C	-	-	-	Aldo/keto reductase family
CMANEAJM_01476	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_01477	3.58e-18	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_01478	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_01479	2.6e-313	-	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_01482	1.14e-156	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
CMANEAJM_01483	5.23e-179	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
CMANEAJM_01484	1.74e-123	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
CMANEAJM_01485	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_01486	3.34e-199	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
CMANEAJM_01487	1.14e-133	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_01488	3.05e-126	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMANEAJM_01489	3.57e-172	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_01490	2.44e-97	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_01491	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
CMANEAJM_01492	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
CMANEAJM_01493	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
CMANEAJM_01494	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
CMANEAJM_01495	2.67e-253	-	-	-	EGP	-	-	-	Major facilitator Superfamily
CMANEAJM_01496	2.28e-221	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01497	1.18e-225	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CMANEAJM_01498	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino acid permease
CMANEAJM_01499	1.19e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
CMANEAJM_01500	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
CMANEAJM_01501	3.33e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMANEAJM_01502	1.75e-168	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
CMANEAJM_01503	0.0	-	-	-	-	-	-	-	-
CMANEAJM_01504	2e-52	-	-	-	S	-	-	-	Cytochrome B5
CMANEAJM_01505	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMANEAJM_01506	5.03e-148	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CMANEAJM_01507	3.54e-118	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
CMANEAJM_01508	6.69e-97	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CMANEAJM_01509	1.78e-53	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CMANEAJM_01510	2.9e-115	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMANEAJM_01511	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
CMANEAJM_01512	6.33e-105	-	-	-	-	-	-	-	-
CMANEAJM_01513	5.97e-96	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
CMANEAJM_01514	1.86e-242	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMANEAJM_01515	7.3e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMANEAJM_01516	7.16e-30	-	-	-	-	-	-	-	-
CMANEAJM_01517	8.5e-133	-	-	-	-	-	-	-	-
CMANEAJM_01518	6.98e-210	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_01519	3.56e-313	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
CMANEAJM_01520	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CMANEAJM_01521	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
CMANEAJM_01522	7.99e-184	-	-	-	S	-	-	-	zinc-ribbon domain
CMANEAJM_01524	4.29e-50	-	-	-	-	-	-	-	-
CMANEAJM_01525	5.17e-172	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
CMANEAJM_01526	4.74e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
CMANEAJM_01527	0.0	-	-	-	I	-	-	-	acetylesterase activity
CMANEAJM_01528	6.34e-301	-	-	-	M	-	-	-	Collagen binding domain
CMANEAJM_01529	2.82e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
CMANEAJM_01530	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
CMANEAJM_01531	4.38e-50	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
CMANEAJM_01532	1.04e-151	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
CMANEAJM_01533	1.98e-142	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
CMANEAJM_01534	8.76e-63	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CMANEAJM_01535	9.16e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
CMANEAJM_01536	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
CMANEAJM_01537	5.24e-124	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
CMANEAJM_01538	8.08e-154	ydgI3	-	-	C	-	-	-	Nitroreductase family
CMANEAJM_01539	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMANEAJM_01540	1.21e-149	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMANEAJM_01541	2.89e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
CMANEAJM_01542	7.28e-218	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01543	3.06e-305	-	-	-	-	-	-	-	-
CMANEAJM_01544	1.4e-82	-	-	-	-	-	-	-	-
CMANEAJM_01545	4.35e-239	-	-	-	S	-	-	-	Cell surface protein
CMANEAJM_01546	2.56e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_01547	1.91e-124	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
CMANEAJM_01548	7.96e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_01549	1.28e-180	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
CMANEAJM_01550	1.88e-192	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CMANEAJM_01551	6.9e-164	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
CMANEAJM_01552	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
CMANEAJM_01554	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_01555	1.15e-43	-	-	-	-	-	-	-	-
CMANEAJM_01556	2.93e-169	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
CMANEAJM_01557	6.19e-40	gtcA3	-	-	S	-	-	-	GtrA-like protein
CMANEAJM_01558	3.43e-73	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01559	8.43e-66	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01560	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMANEAJM_01561	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
CMANEAJM_01562	7.03e-62	-	-	-	-	-	-	-	-
CMANEAJM_01563	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
CMANEAJM_01564	3.36e-62	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
CMANEAJM_01565	6.49e-123	-	-	-	P	-	-	-	Cadmium resistance transporter
CMANEAJM_01566	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01567	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
CMANEAJM_01568	2.03e-84	-	-	-	-	-	-	-	-
CMANEAJM_01569	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
CMANEAJM_01570	2.45e-73	-	-	-	-	-	-	-	-
CMANEAJM_01571	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_01572	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMANEAJM_01573	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_01574	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_01575	2.64e-80	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01576	5.54e-215	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01577	1.57e-237	-	-	-	GM	-	-	-	Male sterility protein
CMANEAJM_01578	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_01579	4.61e-101	-	-	-	M	-	-	-	LysM domain
CMANEAJM_01580	5.02e-129	-	-	-	M	-	-	-	Lysin motif
CMANEAJM_01581	1.64e-137	-	-	-	S	-	-	-	SdpI/YhfL protein family
CMANEAJM_01582	1.58e-72	nudA	-	-	S	-	-	-	ASCH
CMANEAJM_01583	5.76e-212	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CMANEAJM_01584	5.72e-157	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
CMANEAJM_01585	6.14e-282	-	-	-	T	-	-	-	diguanylate cyclase
CMANEAJM_01586	5.23e-97	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CMANEAJM_01587	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
CMANEAJM_01588	8.21e-215	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
CMANEAJM_01589	6.57e-91	-	-	-	-	-	-	-	-
CMANEAJM_01590	2.66e-167	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_01591	8.08e-155	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
CMANEAJM_01592	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01593	1.17e-120	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CMANEAJM_01594	5.51e-101	yphH	-	-	S	-	-	-	Cupin domain
CMANEAJM_01595	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
CMANEAJM_01596	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
CMANEAJM_01597	8.04e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01598	3.26e-251	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_01599	2.31e-277	-	-	-	-	-	-	-	-
CMANEAJM_01600	0.0	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_01601	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01602	1.65e-21	-	-	-	-	-	-	-	-
CMANEAJM_01603	1.47e-286	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
CMANEAJM_01604	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
CMANEAJM_01606	3.44e-17	-	-	-	-	-	-	-	-
CMANEAJM_01607	8.63e-186	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01608	0.0	-	-	-	E	-	-	-	Amino Acid
CMANEAJM_01609	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
CMANEAJM_01610	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
CMANEAJM_01611	3.23e-270	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
CMANEAJM_01612	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CMANEAJM_01613	2.04e-56	-	-	-	S	-	-	-	Cupredoxin-like domain
CMANEAJM_01614	1.02e-32	-	-	-	S	-	-	-	Cupredoxin-like domain
CMANEAJM_01615	9.43e-145	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CMANEAJM_01616	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CMANEAJM_01617	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_01618	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
CMANEAJM_01619	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CMANEAJM_01620	0.0	-	-	-	-	-	-	-	-
CMANEAJM_01621	2.69e-99	-	-	-	-	-	-	-	-
CMANEAJM_01622	1.65e-242	-	-	-	S	-	-	-	Cell surface protein
CMANEAJM_01623	6.02e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_01624	4.62e-226	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
CMANEAJM_01625	1.05e-89	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
CMANEAJM_01626	1.36e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
CMANEAJM_01627	1.49e-242	ynjC	-	-	S	-	-	-	Cell surface protein
CMANEAJM_01628	2.57e-128	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_01629	2.98e-168	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
CMANEAJM_01630	2.33e-128	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
CMANEAJM_01631	3.23e-154	-	-	-	-	-	-	-	-
CMANEAJM_01632	3.69e-150	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
CMANEAJM_01633	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
CMANEAJM_01634	1.23e-195	-	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_01635	3.8e-54	-	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_01636	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CMANEAJM_01637	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CMANEAJM_01638	1.14e-173	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CMANEAJM_01639	1.77e-282	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CMANEAJM_01640	2.41e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_01641	5.35e-216	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_01642	5.33e-253	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CMANEAJM_01643	2.72e-67	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
CMANEAJM_01644	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
CMANEAJM_01645	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
CMANEAJM_01646	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CMANEAJM_01647	3.27e-170	-	-	-	S	-	-	-	KR domain
CMANEAJM_01648	2.46e-127	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_01649	3.74e-139	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
CMANEAJM_01650	7.47e-260	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMANEAJM_01651	7.53e-201	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
CMANEAJM_01652	4.71e-209	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_01653	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CMANEAJM_01654	0.0	-	-	-	S	-	-	-	MucBP domain
CMANEAJM_01655	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CMANEAJM_01656	1.85e-41	-	-	-	-	-	-	-	-
CMANEAJM_01658	4.18e-201	is18	-	-	L	-	-	-	Integrase core domain
CMANEAJM_01659	4.17e-55	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
CMANEAJM_01661	1.43e-186	licT2	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMANEAJM_01662	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01663	0.0	-	-	-	G	ko:K02752,ko:K02753,ko:K02755,ko:K02756,ko:K02757	ko00010,ko02060,map00010,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_01664	1.53e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMANEAJM_01665	0.0	-	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMANEAJM_01666	8.26e-307	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMANEAJM_01667	2.61e-64	sgaB	2.7.1.194, 2.7.1.200	-	G	ko:K02774,ko:K02822,ko:K03475	ko00052,ko00053,ko01100,ko01120,ko02060,map00052,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CMANEAJM_01668	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_01669	1.91e-280	-	-	-	S	-	-	-	Membrane
CMANEAJM_01670	1.32e-34	yoaZ	-	-	S	-	-	-	intracellular protease amidase
CMANEAJM_01671	5.81e-92	-	-	-	K	-	-	-	transcriptional regulator
CMANEAJM_01672	2.76e-185	-	-	-	S	-	-	-	Alpha/beta hydrolase family
CMANEAJM_01673	2.15e-211	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
CMANEAJM_01674	6.07e-155	-	-	-	L	-	-	-	Helix-turn-helix domain
CMANEAJM_01675	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CMANEAJM_01676	1.86e-58	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
CMANEAJM_01677	7.55e-76	-	-	-	-	-	-	-	-
CMANEAJM_01678	4.15e-81	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_01679	5.31e-66	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_01680	1.37e-234	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
CMANEAJM_01682	1.84e-109	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
CMANEAJM_01683	5.45e-153	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CMANEAJM_01684	3.32e-75	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CMANEAJM_01685	3.31e-81	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
CMANEAJM_01686	1.93e-139	-	-	-	GM	-	-	-	NAD(P)H-binding
CMANEAJM_01687	2.18e-101	-	-	-	GM	-	-	-	SnoaL-like domain
CMANEAJM_01688	0.0	qacA	-	-	EGP	-	-	-	Fungal trichothecene efflux pump (TRI12)
CMANEAJM_01689	2.17e-65	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
CMANEAJM_01690	1.79e-07	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
CMANEAJM_01691	7.9e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_01692	9.59e-45	-	-	-	L	ko:K07483	-	ko00000	transposase activity
CMANEAJM_01694	6.79e-53	-	-	-	-	-	-	-	-
CMANEAJM_01695	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMANEAJM_01696	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
CMANEAJM_01697	2.66e-270	xylR	-	-	GK	-	-	-	ROK family
CMANEAJM_01698	3.47e-149	-	-	-	-	-	-	-	-
CMANEAJM_01699	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
CMANEAJM_01700	3.32e-210	-	-	-	-	-	-	-	-
CMANEAJM_01701	2.86e-183	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
CMANEAJM_01702	6.55e-58	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
CMANEAJM_01703	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
CMANEAJM_01704	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
CMANEAJM_01705	9.69e-99	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
CMANEAJM_01706	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_01707	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_01708	2.07e-40	-	-	-	-	-	-	-	-
CMANEAJM_01709	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMANEAJM_01710	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
CMANEAJM_01711	2.05e-167	-	-	-	E	-	-	-	branched-chain amino acid
CMANEAJM_01712	2.76e-115	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
CMANEAJM_01713	7.61e-305	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CMANEAJM_01714	1.61e-272	hpk31	-	-	T	-	-	-	Histidine kinase
CMANEAJM_01715	1.14e-159	vanR	-	-	K	-	-	-	response regulator
CMANEAJM_01716	2.4e-161	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
CMANEAJM_01717	1.31e-111	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMANEAJM_01718	1.63e-78	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMANEAJM_01719	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMANEAJM_01720	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
CMANEAJM_01721	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMANEAJM_01722	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
CMANEAJM_01723	6.14e-202	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CMANEAJM_01724	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
CMANEAJM_01725	6.07e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
CMANEAJM_01726	2.47e-166	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
CMANEAJM_01727	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
CMANEAJM_01728	4.89e-198	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
CMANEAJM_01729	3.01e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_01730	1.37e-215	-	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_01731	1.2e-301	-	-	-	EK	-	-	-	Aminotransferase, class I
CMANEAJM_01732	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CMANEAJM_01733	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_01734	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_01735	7.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
CMANEAJM_01736	9.39e-74	-	-	-	KT	-	-	-	response to antibiotic
CMANEAJM_01737	4.25e-31	-	-	-	KT	-	-	-	response to antibiotic
CMANEAJM_01738	1.82e-66	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_01739	4.06e-131	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
CMANEAJM_01740	5.01e-204	-	-	-	S	-	-	-	Putative adhesin
CMANEAJM_01741	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_01742	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMANEAJM_01743	2.6e-233	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
CMANEAJM_01744	7.52e-263	-	-	-	S	-	-	-	DUF218 domain
CMANEAJM_01745	8.17e-164	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
CMANEAJM_01746	2.06e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
CMANEAJM_01747	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMANEAJM_01748	6.26e-101	-	-	-	-	-	-	-	-
CMANEAJM_01749	1.98e-196	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
CMANEAJM_01750	5.86e-189	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CMANEAJM_01751	3.88e-55	-	-	-	K	-	-	-	MerR family regulatory protein
CMANEAJM_01752	6.31e-22	-	-	-	K	-	-	-	MerR family regulatory protein
CMANEAJM_01753	1.12e-201	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_01754	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_01755	5.08e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
CMANEAJM_01757	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CMANEAJM_01759	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
CMANEAJM_01760	8.57e-75	-	-	-	-	-	-	-	-
CMANEAJM_01761	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
CMANEAJM_01762	1.28e-77	-	-	-	S	-	-	-	Enterocin A Immunity
CMANEAJM_01763	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
CMANEAJM_01764	1.07e-67	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
CMANEAJM_01765	1.62e-134	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_01766	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
CMANEAJM_01767	4.1e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
CMANEAJM_01768	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
CMANEAJM_01769	1.03e-34	-	-	-	-	-	-	-	-
CMANEAJM_01770	8.54e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
CMANEAJM_01771	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
CMANEAJM_01772	8.52e-212	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
CMANEAJM_01773	1.85e-224	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
CMANEAJM_01774	4.27e-253	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CMANEAJM_01775	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CMANEAJM_01776	2.49e-73	-	-	-	S	-	-	-	Enterocin A Immunity
CMANEAJM_01777	5.62e-41	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CMANEAJM_01778	7.41e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMANEAJM_01779	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMANEAJM_01780	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMANEAJM_01781	2.5e-188	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CMANEAJM_01782	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMANEAJM_01784	1.18e-82	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_01785	3.62e-185	-	-	-	S	ko:K01421	-	ko00000	ABC-2 family transporter protein
CMANEAJM_01786	2.45e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
CMANEAJM_01787	2.78e-108	-	-	-	-	-	-	-	-
CMANEAJM_01788	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
CMANEAJM_01790	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CMANEAJM_01791	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_01792	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_01793	2.19e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_01794	1.93e-160	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMANEAJM_01795	1.79e-227	ydbI	-	-	K	-	-	-	AI-2E family transporter
CMANEAJM_01796	4.12e-277	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
CMANEAJM_01797	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
CMANEAJM_01798	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
CMANEAJM_01799	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
CMANEAJM_01800	1.72e-71	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_01801	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
CMANEAJM_01802	6.62e-133	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_01804	8.03e-28	-	-	-	-	-	-	-	-
CMANEAJM_01805	3.91e-124	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CMANEAJM_01806	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
CMANEAJM_01807	3.47e-135	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
CMANEAJM_01808	0.0	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
CMANEAJM_01809	1.8e-134	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
CMANEAJM_01810	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
CMANEAJM_01811	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CMANEAJM_01812	1.42e-107	cvpA	-	-	S	-	-	-	Colicin V production protein
CMANEAJM_01813	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CMANEAJM_01814	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_01816	4.54e-54	-	-	-	-	-	-	-	-
CMANEAJM_01817	2.04e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
CMANEAJM_01818	6.21e-124	-	-	-	V	-	-	-	VanZ like family
CMANEAJM_01819	1.87e-249	-	-	-	V	-	-	-	Beta-lactamase
CMANEAJM_01820	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
CMANEAJM_01821	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CMANEAJM_01822	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
CMANEAJM_01823	1.05e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
CMANEAJM_01824	2.42e-127	-	-	-	FG	-	-	-	HIT domain
CMANEAJM_01825	8.46e-50	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
CMANEAJM_01826	4.29e-101	-	-	-	-	-	-	-	-
CMANEAJM_01827	1.3e-157	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
CMANEAJM_01828	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
CMANEAJM_01829	4.67e-15	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
CMANEAJM_01830	0.0	cadA	-	-	P	-	-	-	P-type ATPase
CMANEAJM_01832	6.23e-160	-	-	-	S	-	-	-	YjbR
CMANEAJM_01833	4.13e-27	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
CMANEAJM_01834	1.01e-218	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
CMANEAJM_01835	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CMANEAJM_01836	2.04e-255	glmS2	-	-	M	-	-	-	SIS domain
CMANEAJM_01837	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
CMANEAJM_01838	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CMANEAJM_01839	9.04e-317	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
CMANEAJM_01840	4.01e-150	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_01841	9.93e-49	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_01842	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
CMANEAJM_01843	7.07e-154	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_01844	6.83e-28	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_01845	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
CMANEAJM_01846	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
CMANEAJM_01847	1.41e-86	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
CMANEAJM_01848	1.7e-70	-	-	-	-	-	-	-	-
CMANEAJM_01849	1.17e-273	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
CMANEAJM_01850	2.11e-82	-	-	-	-	-	-	-	-
CMANEAJM_01851	1.36e-112	-	-	-	-	-	-	-	-
CMANEAJM_01852	3.22e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CMANEAJM_01853	2.27e-74	-	-	-	-	-	-	-	-
CMANEAJM_01854	4.79e-21	-	-	-	-	-	-	-	-
CMANEAJM_01855	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
CMANEAJM_01856	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
CMANEAJM_01857	1.34e-202	-	-	-	EG	-	-	-	EamA-like transporter family
CMANEAJM_01858	2.66e-155	-	-	-	S	-	-	-	membrane
CMANEAJM_01859	1.47e-144	-	-	-	S	-	-	-	VIT family
CMANEAJM_01861	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
CMANEAJM_01862	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
CMANEAJM_01863	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
CMANEAJM_01864	4.26e-54	-	-	-	-	-	-	-	-
CMANEAJM_01865	1.99e-95	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
CMANEAJM_01866	4.94e-25	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
CMANEAJM_01867	1.47e-283	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
CMANEAJM_01868	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CMANEAJM_01869	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
CMANEAJM_01870	7.21e-35	-	-	-	-	-	-	-	-
CMANEAJM_01871	6.94e-16	-	-	-	-	-	-	-	-
CMANEAJM_01872	8.75e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
CMANEAJM_01873	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
CMANEAJM_01874	4.01e-125	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CMANEAJM_01875	2.03e-71	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CMANEAJM_01876	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
CMANEAJM_01877	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
CMANEAJM_01878	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
CMANEAJM_01879	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
CMANEAJM_01880	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
CMANEAJM_01881	2.8e-205	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
CMANEAJM_01882	1.36e-209	yvgN	-	-	C	-	-	-	Aldo keto reductase
CMANEAJM_01883	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
CMANEAJM_01884	2.93e-102	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CMANEAJM_01885	1.05e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
CMANEAJM_01886	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CMANEAJM_01887	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
CMANEAJM_01888	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
CMANEAJM_01889	1.58e-66	-	-	-	-	-	-	-	-
CMANEAJM_01890	6.12e-61	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CMANEAJM_01891	2.87e-140	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
CMANEAJM_01892	0.0	-	-	-	-	-	-	-	-
CMANEAJM_01893	1.36e-245	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
CMANEAJM_01894	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_01895	1.81e-223	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_01896	1.63e-176	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
CMANEAJM_01897	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CMANEAJM_01898	1.76e-32	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_01899	1.84e-99	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_01900	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
CMANEAJM_01901	4.45e-38	-	-	-	-	-	-	-	-
CMANEAJM_01902	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
CMANEAJM_01903	2.04e-107	-	-	-	M	-	-	-	PFAM NLP P60 protein
CMANEAJM_01904	6.18e-71	-	-	-	-	-	-	-	-
CMANEAJM_01905	9.96e-82	-	-	-	-	-	-	-	-
CMANEAJM_01907	8.86e-139	-	-	-	-	-	-	-	-
CMANEAJM_01908	1.22e-68	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
CMANEAJM_01909	1.13e-204	-	-	-	S	ko:K07045	-	ko00000	Amidohydrolase
CMANEAJM_01910	6.25e-132	-	-	-	K	-	-	-	transcriptional regulator
CMANEAJM_01911	1.24e-232	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
CMANEAJM_01912	4.16e-175	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CMANEAJM_01913	1.44e-163	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
CMANEAJM_01914	5.07e-235	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
CMANEAJM_01915	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
CMANEAJM_01916	8.08e-184	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_01917	5.73e-73	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
CMANEAJM_01918	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
CMANEAJM_01919	1.01e-26	-	-	-	-	-	-	-	-
CMANEAJM_01920	1.43e-124	dpsB	-	-	P	-	-	-	Belongs to the Dps family
CMANEAJM_01921	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
CMANEAJM_01922	2.59e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
CMANEAJM_01923	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
CMANEAJM_01924	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CMANEAJM_01925	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
CMANEAJM_01926	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMANEAJM_01927	5.1e-97	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_01928	3.13e-121	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMANEAJM_01929	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
CMANEAJM_01930	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_01931	6.02e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
CMANEAJM_01932	7.83e-60	-	-	-	-	-	-	-	-
CMANEAJM_01933	9.96e-135	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
CMANEAJM_01934	1.03e-65	-	-	-	-	-	-	-	-
CMANEAJM_01935	6.54e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
CMANEAJM_01936	1.64e-282	-	-	-	S	-	-	-	associated with various cellular activities
CMANEAJM_01937	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_01938	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
CMANEAJM_01939	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CMANEAJM_01940	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CMANEAJM_01941	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
CMANEAJM_01942	2.43e-125	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
CMANEAJM_01943	4.85e-16	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_01944	9.07e-208	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_01945	1.38e-84	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
CMANEAJM_01946	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
CMANEAJM_01947	2.13e-295	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
CMANEAJM_01948	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
CMANEAJM_01949	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
CMANEAJM_01950	1.29e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CMANEAJM_01951	6.48e-142	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
CMANEAJM_01952	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
CMANEAJM_01953	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_01954	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
CMANEAJM_01955	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CMANEAJM_01956	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMANEAJM_01957	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
CMANEAJM_01958	6.68e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
CMANEAJM_01959	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CMANEAJM_01960	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
CMANEAJM_01961	3.51e-252	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CMANEAJM_01962	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_01963	2.1e-247	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
CMANEAJM_01964	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
CMANEAJM_01965	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CMANEAJM_01966	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMANEAJM_01967	2.2e-173	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CMANEAJM_01968	7.89e-213	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMANEAJM_01969	3.14e-127	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CMANEAJM_01970	7.63e-74	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CMANEAJM_01971	3.98e-207	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_01972	1.33e-61	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_01973	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMANEAJM_01974	8.63e-15	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMANEAJM_01975	1.61e-163	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMANEAJM_01976	3.87e-201	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
CMANEAJM_01977	9.22e-211	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
CMANEAJM_01978	5.77e-214	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
CMANEAJM_01979	2.25e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_01980	2.97e-83	-	-	-	-	-	-	-	-
CMANEAJM_01981	8.46e-197	estA	-	-	S	-	-	-	Putative esterase
CMANEAJM_01982	5.44e-174	-	-	-	K	-	-	-	UTRA domain
CMANEAJM_01983	0.0	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_01984	6.57e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CMANEAJM_01985	8.73e-205	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
CMANEAJM_01986	7.57e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
CMANEAJM_01987	8.74e-151	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
CMANEAJM_01988	3.11e-57	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMANEAJM_01989	5.18e-209	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMANEAJM_01990	0.0	-	-	-	C	-	-	-	FAD binding domain
CMANEAJM_01991	1.35e-114	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
CMANEAJM_01992	3.56e-311	-	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Alpha mannosidase, middle domain
CMANEAJM_01993	1.51e-291	-	-	-	GT	-	-	-	Phosphotransferase System
CMANEAJM_01994	2.2e-65	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMANEAJM_01995	2.69e-132	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01996	4.7e-214	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_01997	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_01998	1.85e-152	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMANEAJM_01999	9.42e-196	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_02000	1.01e-152	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_02001	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_02002	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_02003	1.3e-203	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMANEAJM_02004	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CMANEAJM_02005	2.66e-222	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
CMANEAJM_02006	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
CMANEAJM_02007	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
CMANEAJM_02009	4.02e-237	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMANEAJM_02010	1.49e-185	yxeH	-	-	S	-	-	-	hydrolase
CMANEAJM_02011	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMANEAJM_02012	2.05e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMANEAJM_02013	8.06e-165	alsE	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
CMANEAJM_02014	3.64e-224	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
CMANEAJM_02015	6.25e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_02016	1.91e-98	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_02017	2.28e-08	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_02018	2.67e-311	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
CMANEAJM_02019	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
CMANEAJM_02020	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMANEAJM_02021	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_02022	1.1e-103	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_02023	3.01e-118	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
CMANEAJM_02024	4.34e-31	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
CMANEAJM_02025	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
CMANEAJM_02026	8.58e-94	yueI	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CMANEAJM_02027	4.05e-113	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
CMANEAJM_02028	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
CMANEAJM_02029	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
CMANEAJM_02030	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
CMANEAJM_02031	0.0	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CMANEAJM_02032	1.4e-261	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_02033	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMANEAJM_02034	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
CMANEAJM_02035	4.93e-208	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMANEAJM_02036	9.55e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMANEAJM_02037	2.29e-207	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMANEAJM_02038	1.8e-110	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMANEAJM_02039	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMANEAJM_02040	3.83e-174	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
CMANEAJM_02041	2.93e-200	nanK	-	-	GK	-	-	-	ROK family
CMANEAJM_02042	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
CMANEAJM_02043	5.52e-92	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02044	5.24e-77	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02045	3.03e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CMANEAJM_02046	7.62e-290	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
CMANEAJM_02047	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
CMANEAJM_02048	1.22e-115	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
CMANEAJM_02049	1.06e-16	-	-	-	-	-	-	-	-
CMANEAJM_02050	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
CMANEAJM_02051	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
CMANEAJM_02052	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
CMANEAJM_02053	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CMANEAJM_02054	3.78e-212	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CMANEAJM_02055	9.62e-19	-	-	-	-	-	-	-	-
CMANEAJM_02056	1.34e-65	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
CMANEAJM_02057	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
CMANEAJM_02058	2.88e-45	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
CMANEAJM_02059	9.98e-237	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_02060	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
CMANEAJM_02061	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
CMANEAJM_02062	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CMANEAJM_02063	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMANEAJM_02064	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CMANEAJM_02065	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
CMANEAJM_02066	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
CMANEAJM_02067	1.23e-128	padR	-	-	K	-	-	-	Virulence activator alpha C-term
CMANEAJM_02068	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
CMANEAJM_02069	4.08e-180	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
CMANEAJM_02070	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_02071	4.02e-203	degV1	-	-	S	-	-	-	DegV family
CMANEAJM_02072	1.52e-78	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
CMANEAJM_02073	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
CMANEAJM_02075	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
CMANEAJM_02076	1.95e-211	-	-	-	-	-	-	-	-
CMANEAJM_02077	3.18e-148	-	-	-	-	-	-	-	-
CMANEAJM_02079	4.17e-168	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
CMANEAJM_02080	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
CMANEAJM_02081	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMANEAJM_02082	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMANEAJM_02083	2.41e-138	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
CMANEAJM_02084	2.77e-16	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
CMANEAJM_02085	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
CMANEAJM_02086	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_02087	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMANEAJM_02088	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMANEAJM_02089	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMANEAJM_02090	6.73e-266	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMANEAJM_02091	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
CMANEAJM_02092	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMANEAJM_02093	2.62e-290	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMANEAJM_02094	8.61e-130	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMANEAJM_02095	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMANEAJM_02096	5.95e-65	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
CMANEAJM_02097	1.68e-108	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMANEAJM_02098	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMANEAJM_02099	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
CMANEAJM_02100	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CMANEAJM_02101	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
CMANEAJM_02102	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_02103	2.58e-183	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMANEAJM_02104	1.09e-290	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMANEAJM_02105	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_02106	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMANEAJM_02107	6.65e-282	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMANEAJM_02108	8.2e-268	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
CMANEAJM_02109	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
CMANEAJM_02110	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMANEAJM_02111	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
CMANEAJM_02113	1.19e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
CMANEAJM_02114	3.15e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
CMANEAJM_02115	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
CMANEAJM_02116	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
CMANEAJM_02117	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
CMANEAJM_02118	2.54e-50	-	-	-	-	-	-	-	-
CMANEAJM_02119	1.72e-291	sip	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMANEAJM_02120	7.57e-122	-	-	-	K	-	-	-	sequence-specific DNA binding
CMANEAJM_02123	8.27e-15	-	-	-	-	-	-	-	-
CMANEAJM_02124	6.2e-39	-	-	-	-	-	-	-	-
CMANEAJM_02125	1.93e-174	-	-	-	L	-	-	-	DNA replication protein
CMANEAJM_02126	2.51e-14	-	-	-	S	-	-	-	Virulence-associated protein E
CMANEAJM_02127	1.35e-296	-	-	-	S	-	-	-	Virulence-associated protein E
CMANEAJM_02128	3.14e-109	-	-	-	-	-	-	-	-
CMANEAJM_02129	4.23e-33	-	-	-	-	-	-	-	-
CMANEAJM_02130	7.08e-66	-	-	-	S	-	-	-	Head-tail joining protein
CMANEAJM_02131	9.01e-90	-	-	-	L	-	-	-	HNH endonuclease
CMANEAJM_02132	2.22e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
CMANEAJM_02133	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
CMANEAJM_02135	5.9e-258	-	-	-	S	-	-	-	Phage portal protein
CMANEAJM_02136	9.75e-258	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
CMANEAJM_02137	6.84e-80	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
CMANEAJM_02138	9.02e-51	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
CMANEAJM_02139	1.27e-73	-	-	-	-	-	-	-	-
CMANEAJM_02140	2.97e-41	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CMANEAJM_02141	1.03e-54	-	-	-	-	-	-	-	-
CMANEAJM_02143	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CMANEAJM_02144	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMANEAJM_02145	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
CMANEAJM_02146	7.14e-195	yycI	-	-	S	-	-	-	YycH protein
CMANEAJM_02147	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
CMANEAJM_02148	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
CMANEAJM_02149	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMANEAJM_02150	3.46e-124	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_02151	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
CMANEAJM_02152	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
CMANEAJM_02153	6.59e-17	pnb	-	-	C	-	-	-	nitroreductase
CMANEAJM_02154	3.25e-85	pnb	-	-	C	-	-	-	nitroreductase
CMANEAJM_02155	3.27e-147	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
CMANEAJM_02156	1.16e-201	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
CMANEAJM_02157	2.79e-94	-	-	-	C	-	-	-	FMN_bind
CMANEAJM_02158	0.0	-	-	-	C	-	-	-	FMN_bind
CMANEAJM_02159	1.21e-19	-	-	-	C	-	-	-	FMN_bind
CMANEAJM_02160	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CMANEAJM_02161	2.41e-203	-	-	-	K	-	-	-	LysR family
CMANEAJM_02162	2.49e-95	-	-	-	C	-	-	-	FMN binding
CMANEAJM_02163	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMANEAJM_02164	4.06e-211	-	-	-	S	-	-	-	KR domain
CMANEAJM_02165	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
CMANEAJM_02166	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
CMANEAJM_02167	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
CMANEAJM_02168	1.28e-153	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
CMANEAJM_02169	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_02170	2.19e-248	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CMANEAJM_02171	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
CMANEAJM_02172	1.14e-173	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
CMANEAJM_02173	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
CMANEAJM_02174	7.87e-105	-	-	-	S	-	-	-	ASCH
CMANEAJM_02175	3.06e-165	-	-	-	F	-	-	-	glutamine amidotransferase
CMANEAJM_02177	9.65e-220	-	-	-	K	-	-	-	WYL domain
CMANEAJM_02178	8.1e-153	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMANEAJM_02179	0.0	fusA1	-	-	J	-	-	-	elongation factor G
CMANEAJM_02180	6.33e-34	-	-	-	S	-	-	-	Protein of unknown function
CMANEAJM_02181	2.33e-103	-	-	-	S	-	-	-	Protein of unknown function
CMANEAJM_02182	1.28e-196	-	-	-	EG	-	-	-	EamA-like transporter family
CMANEAJM_02183	2.11e-118	yfbM	-	-	K	-	-	-	FR47-like protein
CMANEAJM_02184	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
CMANEAJM_02185	3.42e-234	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
CMANEAJM_02186	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_02187	3.46e-301	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
CMANEAJM_02189	1.73e-217	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CMANEAJM_02190	4.49e-180	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
CMANEAJM_02191	5.61e-98	-	-	-	-	-	-	-	-
CMANEAJM_02192	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
CMANEAJM_02193	5.9e-181	-	-	-	-	-	-	-	-
CMANEAJM_02194	4.07e-05	-	-	-	-	-	-	-	-
CMANEAJM_02195	4.65e-183	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
CMANEAJM_02196	1.67e-54	-	-	-	-	-	-	-	-
CMANEAJM_02197	5.92e-183	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CMANEAJM_02198	1.51e-234	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
CMANEAJM_02199	1.59e-103	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
CMANEAJM_02200	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
CMANEAJM_02201	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
CMANEAJM_02202	9.27e-178	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
CMANEAJM_02203	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
CMANEAJM_02204	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_02205	6.38e-194	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
CMANEAJM_02206	1.23e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
CMANEAJM_02207	5.35e-175	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CMANEAJM_02208	2.91e-189	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
CMANEAJM_02209	2.2e-142	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CMANEAJM_02210	6.15e-263	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
CMANEAJM_02211	1.19e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
CMANEAJM_02212	0.0	-	-	-	L	-	-	-	HIRAN domain
CMANEAJM_02213	3.55e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
CMANEAJM_02214	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
CMANEAJM_02215	2.02e-156	-	-	-	-	-	-	-	-
CMANEAJM_02216	2.94e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
CMANEAJM_02217	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CMANEAJM_02218	1.01e-198	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMANEAJM_02219	1.98e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CMANEAJM_02220	6.11e-88	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
CMANEAJM_02221	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02222	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02223	2.19e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_02224	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CMANEAJM_02225	8.08e-185	-	-	-	F	-	-	-	Phosphorylase superfamily
CMANEAJM_02226	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
CMANEAJM_02227	3.61e-144	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
CMANEAJM_02228	9.35e-101	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02229	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
CMANEAJM_02230	1.35e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
CMANEAJM_02231	1.22e-85	-	-	-	K	-	-	-	LytTr DNA-binding domain
CMANEAJM_02232	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
CMANEAJM_02233	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_02234	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
CMANEAJM_02236	2.16e-204	morA	-	-	S	-	-	-	reductase
CMANEAJM_02237	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
CMANEAJM_02238	7.84e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
CMANEAJM_02239	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
CMANEAJM_02240	6.97e-126	-	-	-	-	-	-	-	-
CMANEAJM_02241	3.26e-115	-	-	-	-	-	-	-	-
CMANEAJM_02242	2.1e-211	-	-	-	-	-	-	-	-
CMANEAJM_02243	4.02e-223	-	-	-	C	-	-	-	Oxidoreductase
CMANEAJM_02244	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
CMANEAJM_02245	9.2e-66	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_02246	2.16e-306	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_02247	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
CMANEAJM_02248	1.71e-164	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CMANEAJM_02249	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CMANEAJM_02250	2.42e-159	-	-	-	-	-	-	-	-
CMANEAJM_02251	3.16e-191	-	-	-	-	-	-	-	-
CMANEAJM_02252	3.37e-115	-	-	-	-	-	-	-	-
CMANEAJM_02253	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
CMANEAJM_02254	3.34e-215	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_02255	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
CMANEAJM_02256	7.7e-149	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
CMANEAJM_02257	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
CMANEAJM_02258	3.18e-32	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
CMANEAJM_02260	5.29e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_02261	1.37e-139	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
CMANEAJM_02262	4.08e-66	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
CMANEAJM_02263	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
CMANEAJM_02264	3.9e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
CMANEAJM_02265	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
CMANEAJM_02266	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_02267	4.39e-244	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
CMANEAJM_02268	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
CMANEAJM_02269	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
CMANEAJM_02270	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
CMANEAJM_02271	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMANEAJM_02272	4.7e-205	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_02273	1.01e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
CMANEAJM_02274	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
CMANEAJM_02275	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMANEAJM_02276	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
CMANEAJM_02277	1.52e-168	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
CMANEAJM_02278	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
CMANEAJM_02279	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02280	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02281	8.23e-61	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
CMANEAJM_02282	1.54e-216	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
CMANEAJM_02283	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
CMANEAJM_02284	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_02285	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
CMANEAJM_02286	2.17e-106	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
CMANEAJM_02287	3.84e-99	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
CMANEAJM_02288	0.0	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMANEAJM_02289	9.92e-212	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
CMANEAJM_02290	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
CMANEAJM_02291	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMANEAJM_02292	6.99e-212	mleR	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_02293	0.0	-	-	-	M	-	-	-	domain protein
CMANEAJM_02295	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
CMANEAJM_02296	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_02297	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_02298	2.65e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
CMANEAJM_02299	1.69e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMANEAJM_02300	5.06e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CMANEAJM_02301	2.73e-147	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
CMANEAJM_02302	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
CMANEAJM_02303	5.62e-41	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CMANEAJM_02304	6.33e-46	-	-	-	-	-	-	-	-
CMANEAJM_02305	1.15e-79	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
CMANEAJM_02306	1.07e-208	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
CMANEAJM_02307	5.06e-277	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMANEAJM_02308	3.81e-18	-	-	-	-	-	-	-	-
CMANEAJM_02309	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMANEAJM_02310	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMANEAJM_02311	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
CMANEAJM_02312	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
CMANEAJM_02313	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMANEAJM_02314	2.02e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
CMANEAJM_02315	6.07e-117	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
CMANEAJM_02316	5.3e-202	dkgB	-	-	S	-	-	-	reductase
CMANEAJM_02317	1.05e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMANEAJM_02318	1.2e-91	-	-	-	-	-	-	-	-
CMANEAJM_02319	3.16e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMANEAJM_02321	1.67e-281	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMANEAJM_02322	8.7e-44	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMANEAJM_02323	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_02324	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
CMANEAJM_02325	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_02326	2.61e-282	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
CMANEAJM_02327	1.21e-111	-	-	-	-	-	-	-	-
CMANEAJM_02328	6.83e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CMANEAJM_02329	7.19e-68	-	-	-	-	-	-	-	-
CMANEAJM_02330	1.22e-125	-	-	-	-	-	-	-	-
CMANEAJM_02331	2.98e-90	-	-	-	-	-	-	-	-
CMANEAJM_02332	2.9e-67	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
CMANEAJM_02333	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
CMANEAJM_02334	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
CMANEAJM_02335	3.26e-160	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
CMANEAJM_02336	1.92e-294	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_02337	3.56e-52	-	-	-	-	-	-	-	-
CMANEAJM_02338	2.96e-266	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
CMANEAJM_02339	8.9e-129	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
CMANEAJM_02340	5.49e-120	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
CMANEAJM_02341	7.47e-20	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
CMANEAJM_02342	1.61e-159	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
CMANEAJM_02343	1.74e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
CMANEAJM_02344	1.3e-241	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
CMANEAJM_02345	2.9e-122	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
CMANEAJM_02346	5.78e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
CMANEAJM_02347	1.68e-200	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
CMANEAJM_02348	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
CMANEAJM_02349	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CMANEAJM_02350	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
CMANEAJM_02351	2.21e-56	-	-	-	-	-	-	-	-
CMANEAJM_02352	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
CMANEAJM_02353	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
CMANEAJM_02354	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_02355	1.2e-59	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
CMANEAJM_02356	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMANEAJM_02357	1.5e-184	-	-	-	-	-	-	-	-
CMANEAJM_02358	2.51e-20	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CMANEAJM_02359	3.13e-95	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CMANEAJM_02360	9.53e-93	-	-	-	-	-	-	-	-
CMANEAJM_02361	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02362	1.05e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_02363	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
CMANEAJM_02364	1.91e-151	-	-	-	-	-	-	-	-
CMANEAJM_02365	2.92e-57	-	-	-	-	-	-	-	-
CMANEAJM_02366	1.55e-55	-	-	-	-	-	-	-	-
CMANEAJM_02367	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_02368	2.2e-86	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
CMANEAJM_02369	1.96e-225	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_02370	6.56e-90	hpk2	-	-	T	-	-	-	Histidine kinase
CMANEAJM_02371	2.5e-210	hpk2	-	-	T	-	-	-	Histidine kinase
CMANEAJM_02372	1.1e-164	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
CMANEAJM_02373	2.42e-65	-	-	-	-	-	-	-	-
CMANEAJM_02374	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMANEAJM_02375	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_02377	3.35e-75	-	-	-	-	-	-	-	-
CMANEAJM_02378	2.87e-56	-	-	-	-	-	-	-	-
CMANEAJM_02379	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CMANEAJM_02380	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
CMANEAJM_02381	1.49e-63	-	-	-	-	-	-	-	-
CMANEAJM_02382	9.44e-157	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
CMANEAJM_02383	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
CMANEAJM_02384	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
CMANEAJM_02385	8.31e-139	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
CMANEAJM_02386	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMANEAJM_02387	6.41e-76	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
CMANEAJM_02388	3.04e-294	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
CMANEAJM_02389	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
CMANEAJM_02390	1.13e-171	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02391	2.75e-156	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02392	6.46e-79	-	-	-	M	-	-	-	Lysin motif
CMANEAJM_02393	3.26e-251	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_02394	1.31e-97	-	-	-	M	-	-	-	LysM domain protein
CMANEAJM_02395	4.2e-88	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
CMANEAJM_02396	4.29e-227	-	-	-	-	-	-	-	-
CMANEAJM_02397	2.8e-169	-	-	-	-	-	-	-	-
CMANEAJM_02398	7.61e-265	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
CMANEAJM_02399	3.36e-256	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
CMANEAJM_02400	3.49e-28	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
CMANEAJM_02401	2.48e-74	-	-	-	-	-	-	-	-
CMANEAJM_02402	8.14e-68	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMANEAJM_02403	1.85e-177	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMANEAJM_02404	1.08e-101	-	-	-	S	ko:K02348	-	ko00000	GNAT family
CMANEAJM_02405	1.38e-44	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02406	2.06e-42	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02407	4.76e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CMANEAJM_02408	3.62e-52	-	-	-	-	-	-	-	-
CMANEAJM_02409	5.3e-265	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_02410	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_02411	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_02412	3.58e-263	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CMANEAJM_02413	4.3e-124	-	-	-	K	-	-	-	Cupin domain
CMANEAJM_02414	2.32e-109	-	-	-	S	-	-	-	ASCH
CMANEAJM_02415	7.66e-111	-	-	-	K	-	-	-	GNAT family
CMANEAJM_02416	1.24e-116	-	-	-	K	-	-	-	acetyltransferase
CMANEAJM_02417	2.06e-30	-	-	-	-	-	-	-	-
CMANEAJM_02418	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
CMANEAJM_02419	4.3e-53	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_02420	7.44e-121	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_02421	1.08e-243	-	-	-	-	-	-	-	-
CMANEAJM_02422	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
CMANEAJM_02423	1.16e-206	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
CMANEAJM_02425	6.77e-305	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
CMANEAJM_02426	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
CMANEAJM_02427	7.28e-42	-	-	-	-	-	-	-	-
CMANEAJM_02429	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMANEAJM_02430	6.4e-54	-	-	-	-	-	-	-	-
CMANEAJM_02431	1.54e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CMANEAJM_02432	2.26e-183	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMANEAJM_02433	9.52e-26	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMANEAJM_02434	6.71e-80	-	-	-	S	-	-	-	CHY zinc finger
CMANEAJM_02435	5.67e-287	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CMANEAJM_02436	2.14e-278	-	-	-	-	-	-	-	-
CMANEAJM_02437	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
CMANEAJM_02438	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CMANEAJM_02439	3.93e-59	-	-	-	-	-	-	-	-
CMANEAJM_02440	9.1e-112	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
CMANEAJM_02441	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
CMANEAJM_02442	3.5e-307	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
CMANEAJM_02443	9e-227	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CMANEAJM_02444	8.95e-60	-	-	-	-	-	-	-	-
CMANEAJM_02445	4.27e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
CMANEAJM_02446	7.16e-155	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
CMANEAJM_02447	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
CMANEAJM_02448	2.83e-68	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
CMANEAJM_02449	1.53e-123	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
CMANEAJM_02450	1.61e-294	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
CMANEAJM_02451	3.41e-107	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
CMANEAJM_02452	2.16e-103	-	-	-	-	-	-	-	-
CMANEAJM_02453	9.88e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CMANEAJM_02454	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
CMANEAJM_02455	1.22e-125	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_02456	3.39e-53	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
CMANEAJM_02457	6.74e-82	-	-	-	-	-	-	-	-
CMANEAJM_02458	2.49e-82	-	-	-	-	-	-	-	-
CMANEAJM_02459	3.48e-214	-	-	-	-	-	-	-	-
CMANEAJM_02460	2.35e-101	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
CMANEAJM_02461	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMANEAJM_02462	1.1e-229	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_02463	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
CMANEAJM_02464	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMANEAJM_02465	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
CMANEAJM_02466	3.04e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_02467	9.42e-212	-	-	-	M	-	-	-	domain protein
CMANEAJM_02468	0.0	-	-	-	M	-	-	-	domain protein
CMANEAJM_02469	7.86e-78	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
CMANEAJM_02470	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
CMANEAJM_02471	4.07e-216	-	-	-	-	-	-	-	-
CMANEAJM_02472	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
CMANEAJM_02473	1.69e-130	-	-	-	S	-	-	-	ankyrin repeats
CMANEAJM_02474	8.47e-46	-	-	-	-	-	-	-	-
CMANEAJM_02475	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02476	1.52e-98	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02477	8.53e-28	-	-	-	-	-	-	-	-
CMANEAJM_02478	5.66e-88	-	-	-	-	-	-	-	-
CMANEAJM_02479	3.94e-215	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_02480	1.4e-40	-	-	-	-	-	-	-	-
CMANEAJM_02481	3.27e-81	-	-	-	-	-	-	-	-
CMANEAJM_02484	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
CMANEAJM_02485	7.81e-263	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
CMANEAJM_02486	4.15e-188	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
CMANEAJM_02487	2.35e-212	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02488	1.39e-190	-	-	-	S	-	-	-	hydrolase
CMANEAJM_02490	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
CMANEAJM_02491	1.6e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMANEAJM_02493	2e-32	-	-	-	-	-	-	-	-
CMANEAJM_02495	2.19e-249	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_02497	9.81e-80	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
CMANEAJM_02498	2.28e-168	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
CMANEAJM_02499	3.32e-166	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02500	1.93e-31	plnF	-	-	-	-	-	-	-
CMANEAJM_02502	6.13e-173	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMANEAJM_02503	1.27e-277	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CMANEAJM_02504	3.84e-77	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
CMANEAJM_02505	1.89e-192	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
CMANEAJM_02506	1.57e-141	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02507	3.26e-151	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02508	3.59e-141	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02509	6.46e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02510	5.5e-42	-	-	-	-	-	-	-	-
CMANEAJM_02511	0.0	-	-	-	L	-	-	-	DNA helicase
CMANEAJM_02512	9.73e-180	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
CMANEAJM_02513	1.36e-242	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMANEAJM_02514	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
CMANEAJM_02515	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_02516	9.68e-34	-	-	-	-	-	-	-	-
CMANEAJM_02517	3.55e-99	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
CMANEAJM_02518	0.0	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_02519	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_02520	6.97e-209	-	-	-	GK	-	-	-	ROK family
CMANEAJM_02521	9.75e-175	yecA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
CMANEAJM_02522	3.43e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMANEAJM_02523	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CMANEAJM_02524	1.12e-57	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CMANEAJM_02525	4.6e-13	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CMANEAJM_02526	1.15e-158	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
CMANEAJM_02527	1.33e-228	-	-	-	-	-	-	-	-
CMANEAJM_02528	1.02e-169	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
CMANEAJM_02529	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
CMANEAJM_02530	1.14e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
CMANEAJM_02531	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMANEAJM_02532	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
CMANEAJM_02533	1.6e-92	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
CMANEAJM_02534	1.83e-27	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
CMANEAJM_02536	1.52e-98	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02537	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02538	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
CMANEAJM_02539	1.02e-55	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMANEAJM_02540	2.5e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMANEAJM_02541	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
CMANEAJM_02542	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CMANEAJM_02543	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
CMANEAJM_02544	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMANEAJM_02545	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
CMANEAJM_02546	3.71e-15	-	-	-	T	ko:K21493	-	ko00000,ko01000,ko02048	Pre-toxin TG
CMANEAJM_02547	8.4e-57	-	-	-	S	-	-	-	ankyrin repeats
CMANEAJM_02548	1.3e-49	-	-	-	-	-	-	-	-
CMANEAJM_02549	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
CMANEAJM_02550	3.28e-298	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMANEAJM_02551	1.95e-215	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_02552	1.28e-251	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_02553	6.19e-80	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CMANEAJM_02554	4.5e-83	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
CMANEAJM_02555	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMANEAJM_02556	1.28e-13	-	-	-	S	-	-	-	DUF218 domain
CMANEAJM_02557	1.21e-206	-	-	-	S	-	-	-	DUF218 domain
CMANEAJM_02558	7.12e-178	-	-	-	-	-	-	-	-
CMANEAJM_02559	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
CMANEAJM_02560	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
CMANEAJM_02561	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
CMANEAJM_02562	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
CMANEAJM_02563	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMANEAJM_02564	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMANEAJM_02565	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CMANEAJM_02566	6.07e-155	-	-	-	L	-	-	-	Helix-turn-helix domain
CMANEAJM_02567	8.29e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMANEAJM_02568	1.22e-27	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
CMANEAJM_02569	1.11e-241	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
CMANEAJM_02570	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
CMANEAJM_02571	3.28e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
CMANEAJM_02572	6.59e-170	-	-	-	S	-	-	-	YheO-like PAS domain
CMANEAJM_02573	4.01e-36	-	-	-	-	-	-	-	-
CMANEAJM_02574	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMANEAJM_02575	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CMANEAJM_02576	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
CMANEAJM_02577	7.05e-145	-	-	-	J	-	-	-	translation release factor activity
CMANEAJM_02578	4.03e-111	-	-	-	J	-	-	-	translation release factor activity
CMANEAJM_02579	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
CMANEAJM_02580	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
CMANEAJM_02581	5.58e-195	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
CMANEAJM_02582	1.84e-189	-	-	-	-	-	-	-	-
CMANEAJM_02583	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMANEAJM_02584	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMANEAJM_02585	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMANEAJM_02586	1.43e-274	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMANEAJM_02587	1.98e-44	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
CMANEAJM_02588	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
CMANEAJM_02589	1.28e-245	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_02590	3.03e-194	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
CMANEAJM_02591	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
CMANEAJM_02592	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
CMANEAJM_02593	2.18e-123	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CMANEAJM_02594	7.93e-107	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
CMANEAJM_02595	3.61e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CMANEAJM_02596	1.61e-292	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CMANEAJM_02597	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
CMANEAJM_02598	4.47e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
CMANEAJM_02599	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CMANEAJM_02600	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
CMANEAJM_02601	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
CMANEAJM_02602	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
CMANEAJM_02603	2.79e-226	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CMANEAJM_02604	8.29e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMANEAJM_02605	3.04e-262	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMANEAJM_02606	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMANEAJM_02607	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
CMANEAJM_02608	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
CMANEAJM_02610	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
CMANEAJM_02611	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
CMANEAJM_02612	3.53e-223	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMANEAJM_02613	1.99e-80	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMANEAJM_02614	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
CMANEAJM_02615	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMANEAJM_02616	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMANEAJM_02617	6.22e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMANEAJM_02618	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
CMANEAJM_02621	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
CMANEAJM_02624	6.41e-152	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
CMANEAJM_02625	7.75e-176	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
CMANEAJM_02626	6.09e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
CMANEAJM_02630	9.02e-66	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
CMANEAJM_02631	1.38e-71	-	-	-	S	-	-	-	Cupin domain
CMANEAJM_02632	5.35e-213	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
CMANEAJM_02633	1.59e-247	ysdE	-	-	P	-	-	-	Citrate transporter
CMANEAJM_02634	4.33e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
CMANEAJM_02635	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMANEAJM_02636	2.92e-280	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMANEAJM_02637	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
CMANEAJM_02638	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CMANEAJM_02639	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMANEAJM_02640	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMANEAJM_02641	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
CMANEAJM_02642	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
CMANEAJM_02643	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
CMANEAJM_02644	3.76e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
CMANEAJM_02645	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
CMANEAJM_02646	1.19e-201	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMANEAJM_02648	6.78e-199	-	-	-	G	-	-	-	Peptidase_C39 like family
CMANEAJM_02649	6.46e-218	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMANEAJM_02650	4.51e-172	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
CMANEAJM_02651	4.22e-216	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
CMANEAJM_02652	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
CMANEAJM_02653	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
CMANEAJM_02654	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMANEAJM_02655	3.66e-59	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMANEAJM_02656	5.3e-29	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMANEAJM_02657	3.15e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMANEAJM_02658	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
CMANEAJM_02659	3.78e-316	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
CMANEAJM_02660	6.33e-185	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMANEAJM_02661	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
CMANEAJM_02662	2.29e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CMANEAJM_02663	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
CMANEAJM_02664	6.04e-227	-	-	-	EG	-	-	-	EamA-like transporter family
CMANEAJM_02665	3.3e-166	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CMANEAJM_02666	4.57e-147	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
CMANEAJM_02667	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
CMANEAJM_02668	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CMANEAJM_02669	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
CMANEAJM_02670	3.29e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
CMANEAJM_02671	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMANEAJM_02672	4.91e-265	yacL	-	-	S	-	-	-	domain protein
CMANEAJM_02673	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMANEAJM_02674	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
CMANEAJM_02675	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMANEAJM_02676	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMANEAJM_02677	6.12e-127	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
CMANEAJM_02678	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
CMANEAJM_02679	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
CMANEAJM_02680	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMANEAJM_02681	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
CMANEAJM_02682	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_02683	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMANEAJM_02684	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMANEAJM_02685	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMANEAJM_02686	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMANEAJM_02687	1.29e-254	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_02688	2.89e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
CMANEAJM_02689	1.16e-66	-	-	-	L	-	-	-	nuclease
CMANEAJM_02690	2.71e-262	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMANEAJM_02691	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMANEAJM_02692	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
CMANEAJM_02693	1.01e-252	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMANEAJM_02694	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMANEAJM_02695	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
CMANEAJM_02696	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
CMANEAJM_02697	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMANEAJM_02698	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMANEAJM_02699	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMANEAJM_02700	5.12e-139	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMANEAJM_02701	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
CMANEAJM_02702	2.48e-98	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_02703	1.49e-81	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_02705	4.97e-67	-	2.7.1.194	-	G	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
CMANEAJM_02706	2.27e-54	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
CMANEAJM_02707	4.67e-280	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
CMANEAJM_02708	3.45e-27	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
CMANEAJM_02709	4.12e-49	eda	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
CMANEAJM_02710	1.82e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMANEAJM_02711	2.03e-13	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CMANEAJM_02712	6.78e-39	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
CMANEAJM_02713	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CMANEAJM_02714	4.9e-76	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
CMANEAJM_02715	1.08e-212	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMANEAJM_02716	6.41e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
CMANEAJM_02717	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
CMANEAJM_02718	3.1e-269	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
CMANEAJM_02719	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
CMANEAJM_02720	3.33e-184	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_02721	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
CMANEAJM_02722	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CMANEAJM_02723	2.84e-241	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
CMANEAJM_02724	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
CMANEAJM_02725	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
CMANEAJM_02726	3.32e-107	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CMANEAJM_02727	6.01e-248	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMANEAJM_02728	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
CMANEAJM_02729	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMANEAJM_02730	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02731	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMANEAJM_02732	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMANEAJM_02733	0.0	ydaO	-	-	E	-	-	-	amino acid
CMANEAJM_02734	1.04e-246	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
CMANEAJM_02735	8.94e-197	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CMANEAJM_02736	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
CMANEAJM_02737	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
CMANEAJM_02738	9.83e-163	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
CMANEAJM_02739	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMANEAJM_02740	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMANEAJM_02741	1.84e-251	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMANEAJM_02742	4.6e-70	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
CMANEAJM_02743	8.14e-186	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
CMANEAJM_02744	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
CMANEAJM_02745	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
CMANEAJM_02746	1.19e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
CMANEAJM_02747	2.99e-71	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CMANEAJM_02748	1.07e-110	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
CMANEAJM_02749	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
CMANEAJM_02750	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMANEAJM_02751	1.68e-86	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMANEAJM_02752	4.55e-70	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMANEAJM_02753	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
CMANEAJM_02754	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
CMANEAJM_02755	2.87e-71	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
CMANEAJM_02756	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMANEAJM_02757	1.04e-211	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMANEAJM_02758	8.05e-233	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
CMANEAJM_02759	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
CMANEAJM_02760	6.37e-160	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CMANEAJM_02761	0.0	nox	-	-	C	-	-	-	NADH oxidase
CMANEAJM_02762	3.18e-207	ydaJ	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 8 (cellulase D) family
CMANEAJM_02763	2.45e-310	-	-	-	-	-	-	-	-
CMANEAJM_02764	8.36e-257	-	-	-	S	-	-	-	Protein conserved in bacteria
CMANEAJM_02765	2.74e-277	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
CMANEAJM_02766	3.47e-295	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
CMANEAJM_02767	1.12e-87	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02768	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02769	2.99e-93	-	-	-	S	-	-	-	Bacterial cellulose synthase subunit
CMANEAJM_02770	8.49e-138	-	-	-	T	-	-	-	diguanylate cyclase activity
CMANEAJM_02771	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMANEAJM_02772	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
CMANEAJM_02773	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
CMANEAJM_02774	4.44e-27	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMANEAJM_02775	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
CMANEAJM_02776	5.9e-170	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
CMANEAJM_02777	3.61e-285	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMANEAJM_02778	2.56e-19	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CMANEAJM_02779	1.77e-98	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
CMANEAJM_02780	7.25e-266	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
CMANEAJM_02781	8.86e-07	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
CMANEAJM_02782	3.94e-116	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
CMANEAJM_02783	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMANEAJM_02784	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMANEAJM_02785	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMANEAJM_02786	7.5e-302	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMANEAJM_02787	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
CMANEAJM_02788	6.07e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
CMANEAJM_02789	1.71e-207	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
CMANEAJM_02790	3.75e-242	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
CMANEAJM_02791	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
CMANEAJM_02792	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_02793	1.55e-225	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMANEAJM_02794	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMANEAJM_02796	5.42e-310	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
CMANEAJM_02797	5.75e-242	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
CMANEAJM_02798	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMANEAJM_02799	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
CMANEAJM_02800	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMANEAJM_02801	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMANEAJM_02802	5.11e-171	-	-	-	-	-	-	-	-
CMANEAJM_02803	1.11e-230	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CMANEAJM_02804	5.84e-121	eriC	-	-	P	ko:K03281	-	ko00000	chloride
CMANEAJM_02805	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
CMANEAJM_02806	1.56e-178	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
CMANEAJM_02807	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMANEAJM_02808	6.89e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CMANEAJM_02809	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
CMANEAJM_02810	5.62e-41	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
CMANEAJM_02811	1.03e-257	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_02812	1.59e-36	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
CMANEAJM_02813	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_02814	5.62e-137	-	-	-	-	-	-	-	-
CMANEAJM_02815	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
CMANEAJM_02816	1.4e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMANEAJM_02817	1.23e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
CMANEAJM_02818	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
CMANEAJM_02819	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
CMANEAJM_02820	7.18e-131	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
CMANEAJM_02821	2.29e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
CMANEAJM_02822	1.47e-211	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
CMANEAJM_02823	4.28e-169	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
CMANEAJM_02824	1.64e-238	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMANEAJM_02825	4.77e-199	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
CMANEAJM_02826	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_02827	6.9e-157	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
CMANEAJM_02828	8.33e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMANEAJM_02829	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
CMANEAJM_02830	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMANEAJM_02831	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMANEAJM_02832	3.15e-158	-	-	-	T	-	-	-	EAL domain
CMANEAJM_02833	1.14e-189	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
CMANEAJM_02834	7.01e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_02835	1.7e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
CMANEAJM_02836	3.38e-70	-	-	-	-	-	-	-	-
CMANEAJM_02837	2.49e-95	-	-	-	-	-	-	-	-
CMANEAJM_02838	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
CMANEAJM_02839	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_02840	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_02841	7.08e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
CMANEAJM_02842	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMANEAJM_02843	5.03e-183	-	-	-	-	-	-	-	-
CMANEAJM_02845	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
CMANEAJM_02846	3.88e-46	-	-	-	-	-	-	-	-
CMANEAJM_02847	2.08e-117	-	-	-	V	-	-	-	VanZ like family
CMANEAJM_02848	3.55e-313	-	-	-	EGP	-	-	-	Major Facilitator
CMANEAJM_02849	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CMANEAJM_02850	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CMANEAJM_02851	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
CMANEAJM_02852	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
CMANEAJM_02853	1.77e-106	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02854	1.36e-27	-	-	-	-	-	-	-	-
CMANEAJM_02855	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CMANEAJM_02856	7.99e-225	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMANEAJM_02857	8.57e-148	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMANEAJM_02858	7.77e-198	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
CMANEAJM_02859	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
CMANEAJM_02860	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
CMANEAJM_02861	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMANEAJM_02862	0.0	oatA	-	-	I	-	-	-	Acyltransferase
CMANEAJM_02863	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CMANEAJM_02864	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
CMANEAJM_02865	1.09e-60	-	-	-	-	-	-	-	-
CMANEAJM_02866	5.56e-310	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
CMANEAJM_02867	6.12e-115	-	-	-	-	-	-	-	-
CMANEAJM_02868	5.24e-191	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
CMANEAJM_02869	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
CMANEAJM_02870	1.48e-27	-	-	-	-	-	-	-	-
CMANEAJM_02871	6.02e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
CMANEAJM_02872	2.02e-106	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
CMANEAJM_02873	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
CMANEAJM_02874	1.01e-188	-	-	-	-	-	-	-	-
CMANEAJM_02875	1.42e-95	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
CMANEAJM_02876	3.21e-268	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CMANEAJM_02877	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMANEAJM_02878	5.2e-54	-	-	-	-	-	-	-	-
CMANEAJM_02880	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
CMANEAJM_02881	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
CMANEAJM_02882	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_02883	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
CMANEAJM_02884	2.99e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
CMANEAJM_02885	1.34e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
CMANEAJM_02886	1.65e-110	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMANEAJM_02887	1.82e-196	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
CMANEAJM_02888	7.45e-181	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
CMANEAJM_02889	9.38e-317	steT	-	-	E	ko:K03294	-	ko00000	amino acid
CMANEAJM_02890	7.32e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_02891	2.97e-189	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
CMANEAJM_02892	1.78e-92	-	-	-	K	-	-	-	MarR family
CMANEAJM_02893	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
CMANEAJM_02894	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMANEAJM_02895	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_02896	5.95e-300	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMANEAJM_02897	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
CMANEAJM_02898	3.5e-64	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
CMANEAJM_02899	1.61e-36	-	-	-	-	-	-	-	-
CMANEAJM_02900	2.23e-164	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
CMANEAJM_02901	6.92e-126	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
CMANEAJM_02902	9.61e-14	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
CMANEAJM_02903	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
CMANEAJM_02904	5.65e-225	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
CMANEAJM_02905	2.84e-146	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
CMANEAJM_02906	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
CMANEAJM_02907	1.46e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
CMANEAJM_02908	2.31e-45	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CMANEAJM_02909	3.29e-156	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
CMANEAJM_02910	3.9e-313	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
CMANEAJM_02911	1.33e-114	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMANEAJM_02913	1.79e-47	-	-	-	S	-	-	-	KilA-N domain
CMANEAJM_02916	2.87e-22	-	-	-	S	-	-	-	Short C-terminal domain
CMANEAJM_02918	5.44e-12	-	-	-	K	-	-	-	transcriptional
CMANEAJM_02920	2.35e-98	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_02921	6.79e-47	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
CMANEAJM_02922	5.08e-129	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
CMANEAJM_02923	1.08e-71	-	-	-	-	-	-	-	-
CMANEAJM_02924	5.57e-83	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_02925	0.0	-	-	-	L	-	-	-	AAA domain
CMANEAJM_02926	2.01e-149	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
CMANEAJM_02927	3.26e-167	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
CMANEAJM_02928	2.26e-79	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
CMANEAJM_02929	2.09e-60	-	-	-	S	-	-	-	MORN repeat
CMANEAJM_02930	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
CMANEAJM_02931	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
CMANEAJM_02932	1.95e-116	-	-	-	-	-	-	-	-
CMANEAJM_02933	5.74e-32	-	-	-	-	-	-	-	-
CMANEAJM_02934	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CMANEAJM_02935	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
CMANEAJM_02936	1.31e-188	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
CMANEAJM_02937	1.85e-168	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
CMANEAJM_02938	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
CMANEAJM_02939	2.66e-132	-	-	-	G	-	-	-	Glycogen debranching enzyme
CMANEAJM_02940	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
CMANEAJM_02941	0.0	hsdR	3.1.21.3	-	V	ko:K01153	-	ko00000,ko01000,ko02048	Subunit R is required for both nuclease and ATPase activities, but not for modification
CMANEAJM_02942	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	type I restriction-modification system
CMANEAJM_02943	6.59e-53	-	-	-	V	-	-	-	Type I restriction modification DNA specificity domain
CMANEAJM_02944	1.41e-68	hsdS	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction modification DNA specificity domain
CMANEAJM_02945	8.93e-220	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
CMANEAJM_02946	5.89e-46	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	type I restriction enzyme, S subunit K01154
CMANEAJM_02947	2.17e-43	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
CMANEAJM_02948	8.38e-120	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
CMANEAJM_02949	0.0	-	-	-	M	-	-	-	MucBP domain
CMANEAJM_02950	1.42e-08	-	-	-	-	-	-	-	-
CMANEAJM_02951	2.87e-112	-	-	-	S	-	-	-	AAA domain
CMANEAJM_02952	1.06e-179	-	-	-	K	-	-	-	sequence-specific DNA binding
CMANEAJM_02953	4.45e-61	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_02954	6.7e-162	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02955	3.69e-22	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02956	0.0	-	-	-	C	-	-	-	FMN_bind
CMANEAJM_02958	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
CMANEAJM_02959	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CMANEAJM_02960	4.3e-106	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_02961	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMANEAJM_02962	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
CMANEAJM_02963	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
CMANEAJM_02964	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
CMANEAJM_02965	4.6e-200	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CMANEAJM_02966	9.6e-63	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CMANEAJM_02967	9.05e-55	-	-	-	-	-	-	-	-
CMANEAJM_02968	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
CMANEAJM_02969	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
CMANEAJM_02970	1.65e-209	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
CMANEAJM_02971	3.52e-24	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_02972	2.49e-06	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_02973	4.34e-135	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
CMANEAJM_02974	1.59e-243	-	-	-	-	-	-	-	-
CMANEAJM_02975	1.83e-242	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
CMANEAJM_02976	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
CMANEAJM_02977	1.22e-132	-	-	-	K	-	-	-	FR47-like protein
CMANEAJM_02978	8.71e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
CMANEAJM_02979	3.33e-64	-	-	-	-	-	-	-	-
CMANEAJM_02980	1.73e-82	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMANEAJM_02981	8.65e-34	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMANEAJM_02982	1.61e-19	xylP2	-	-	G	-	-	-	symporter
CMANEAJM_02983	6.26e-270	xylP2	-	-	G	-	-	-	symporter
CMANEAJM_02984	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMANEAJM_02985	1.2e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
CMANEAJM_02986	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
CMANEAJM_02987	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
CMANEAJM_02988	8.25e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
CMANEAJM_02989	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CMANEAJM_02990	9.04e-179	-	-	-	-	-	-	-	-
CMANEAJM_02991	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
CMANEAJM_02992	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
CMANEAJM_02993	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
CMANEAJM_02994	1.36e-77	-	-	-	-	-	-	-	-
CMANEAJM_02995	1.28e-141	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
CMANEAJM_02996	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
CMANEAJM_02997	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
CMANEAJM_02998	7.76e-100	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
CMANEAJM_02999	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
CMANEAJM_03000	8.37e-153	-	-	-	I	-	-	-	phosphatase
CMANEAJM_03001	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
CMANEAJM_03002	3.03e-129	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
CMANEAJM_03003	1.56e-76	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_03004	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
CMANEAJM_03005	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
CMANEAJM_03006	5.9e-100	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
CMANEAJM_03007	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
CMANEAJM_03008	1.02e-297	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMANEAJM_03016	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
CMANEAJM_03017	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CMANEAJM_03018	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_03019	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMANEAJM_03020	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMANEAJM_03021	1.81e-150	comC	3.4.23.43	-	NOU	ko:K02236	-	ko00000,ko00002,ko01000,ko02044	Bacterial Peptidase A24 N-terminal domain
CMANEAJM_03022	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMANEAJM_03023	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMANEAJM_03024	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMANEAJM_03025	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
CMANEAJM_03026	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMANEAJM_03027	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
CMANEAJM_03028	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMANEAJM_03029	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMANEAJM_03030	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMANEAJM_03031	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMANEAJM_03032	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMANEAJM_03033	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMANEAJM_03034	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
CMANEAJM_03035	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMANEAJM_03036	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMANEAJM_03037	4.1e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMANEAJM_03038	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMANEAJM_03039	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMANEAJM_03040	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMANEAJM_03041	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMANEAJM_03042	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMANEAJM_03043	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
CMANEAJM_03044	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
CMANEAJM_03045	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMANEAJM_03046	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMANEAJM_03047	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMANEAJM_03048	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMANEAJM_03049	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMANEAJM_03050	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMANEAJM_03051	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
CMANEAJM_03052	4.15e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMANEAJM_03053	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
CMANEAJM_03054	5.37e-112	-	-	-	S	-	-	-	NusG domain II
CMANEAJM_03055	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CMANEAJM_03056	8.05e-71	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CMANEAJM_03057	2.21e-09	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
CMANEAJM_03058	3.19e-194	-	-	-	S	-	-	-	FMN_bind
CMANEAJM_03059	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CMANEAJM_03060	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMANEAJM_03061	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMANEAJM_03062	5.1e-123	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMANEAJM_03063	6.84e-145	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMANEAJM_03064	1.41e-28	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMANEAJM_03065	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMANEAJM_03066	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
CMANEAJM_03067	1.21e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
CMANEAJM_03068	2.46e-235	-	-	-	S	-	-	-	Membrane
CMANEAJM_03069	1.22e-100	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
CMANEAJM_03070	7.61e-147	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
CMANEAJM_03071	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMANEAJM_03072	4e-168	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMANEAJM_03073	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
CMANEAJM_03074	1.28e-253	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CMANEAJM_03076	2.37e-280	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CMANEAJM_03077	3.05e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
CMANEAJM_03078	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
CMANEAJM_03079	7.76e-127	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
CMANEAJM_03080	3e-74	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
CMANEAJM_03081	1.55e-254	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_03082	3.44e-164	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
CMANEAJM_03083	2.04e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMANEAJM_03084	2.05e-179	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
CMANEAJM_03085	5.19e-223	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
CMANEAJM_03086	1.18e-66	-	-	-	-	-	-	-	-
CMANEAJM_03087	7.56e-214	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
CMANEAJM_03088	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
CMANEAJM_03089	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
CMANEAJM_03090	1.92e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
CMANEAJM_03091	3.74e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CMANEAJM_03092	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
CMANEAJM_03093	2.73e-209	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
CMANEAJM_03094	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
CMANEAJM_03095	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMANEAJM_03096	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
CMANEAJM_03097	1.24e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CMANEAJM_03098	3.06e-205	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
CMANEAJM_03099	5.34e-214	mleR	-	-	K	-	-	-	LysR family
CMANEAJM_03100	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
CMANEAJM_03101	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
CMANEAJM_03102	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
CMANEAJM_03103	6.47e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
CMANEAJM_03104	6.07e-33	-	-	-	-	-	-	-	-
CMANEAJM_03105	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
CMANEAJM_03106	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
CMANEAJM_03107	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
CMANEAJM_03108	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
CMANEAJM_03109	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CMANEAJM_03110	1.89e-208	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
CMANEAJM_03111	9.6e-201	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
CMANEAJM_03112	8.5e-213	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
CMANEAJM_03113	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
CMANEAJM_03114	2.8e-145	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
CMANEAJM_03115	2.01e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMANEAJM_03116	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
CMANEAJM_03117	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CMANEAJM_03118	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
CMANEAJM_03119	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMANEAJM_03120	9.07e-261	camS	-	-	S	-	-	-	sex pheromone
CMANEAJM_03121	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMANEAJM_03122	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMANEAJM_03123	4.76e-77	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMANEAJM_03124	1.54e-234	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMANEAJM_03125	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
CMANEAJM_03126	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMANEAJM_03127	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
CMANEAJM_03128	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
CMANEAJM_03129	2.5e-298	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_03130	6.57e-195	gntR	-	-	K	-	-	-	rpiR family
CMANEAJM_03131	4.68e-187	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
CMANEAJM_03132	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
CMANEAJM_03133	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
CMANEAJM_03134	7.89e-245	mocA	-	-	S	-	-	-	Oxidoreductase
CMANEAJM_03135	4.68e-57	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CMANEAJM_03136	3.08e-240	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
CMANEAJM_03138	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
CMANEAJM_03139	2.87e-29	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_03140	3.78e-270	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMANEAJM_03141	1.04e-107	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_03142	1.12e-84	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
CMANEAJM_03144	7.62e-97	-	-	-	-	-	-	-	-
CMANEAJM_03145	4.12e-139	-	-	-	-	-	-	-	-
CMANEAJM_03146	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
CMANEAJM_03147	2.22e-169	-	-	-	L	-	-	-	Helix-turn-helix domain
CMANEAJM_03148	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
CMANEAJM_03149	1.1e-279	pbpX	-	-	V	-	-	-	Beta-lactamase
CMANEAJM_03150	3.34e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMANEAJM_03151	7.42e-202	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
CMANEAJM_03152	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_03153	1.52e-98	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_03154	1.56e-78	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_03155	1.06e-68	-	-	-	-	-	-	-	-
CMANEAJM_03156	1.72e-44	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
CMANEAJM_03157	1.95e-41	-	-	-	-	-	-	-	-
CMANEAJM_03158	1.35e-34	-	-	-	-	-	-	-	-
CMANEAJM_03159	6.87e-131	-	-	-	K	-	-	-	DNA-templated transcription, initiation
CMANEAJM_03160	1.9e-168	-	-	-	-	-	-	-	-
CMANEAJM_03161	1.01e-181	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
CMANEAJM_03162	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
CMANEAJM_03163	1.94e-170	lytE	-	-	M	-	-	-	NlpC/P60 family
CMANEAJM_03164	5.64e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
CMANEAJM_03165	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
CMANEAJM_03166	7.3e-216	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
CMANEAJM_03167	4.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
CMANEAJM_03168	6.04e-94	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
CMANEAJM_03169	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
CMANEAJM_03170	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
CMANEAJM_03171	1.42e-217	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
CMANEAJM_03172	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
CMANEAJM_03173	7.08e-180	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMANEAJM_03174	4.5e-183	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CMANEAJM_03175	0.0	-	-	-	-	-	-	-	-
CMANEAJM_03176	1.56e-105	-	-	-	M	-	-	-	MucBP domain
CMANEAJM_03177	8.13e-114	-	-	-	M	-	-	-	MucBP domain
CMANEAJM_03178	1.62e-06	lysR5	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_03179	8.88e-189	lysR5	-	-	K	-	-	-	LysR substrate binding domain
CMANEAJM_03180	1.01e-172	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
CMANEAJM_03181	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
CMANEAJM_03182	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
CMANEAJM_03183	1.76e-41	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMANEAJM_03184	6.78e-158	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMANEAJM_03185	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMANEAJM_03186	3.29e-83	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMANEAJM_03187	1.74e-155	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMANEAJM_03188	2.03e-158	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
CMANEAJM_03189	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
CMANEAJM_03190	1.45e-131	-	-	-	L	-	-	-	Integrase
CMANEAJM_03191	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
CMANEAJM_03192	5.6e-41	-	-	-	-	-	-	-	-
CMANEAJM_03193	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
CMANEAJM_03194	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMANEAJM_03195	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CMANEAJM_03196	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
CMANEAJM_03197	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMANEAJM_03198	2.29e-292	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
CMANEAJM_03199	2.43e-264	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
CMANEAJM_03200	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
CMANEAJM_03201	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
CMANEAJM_03202	1.18e-98	-	-	-	-	-	-	-	-
CMANEAJM_03203	4.93e-55	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
CMANEAJM_03204	1.51e-118	-	-	-	-	-	-	-	-
CMANEAJM_03205	7.6e-268	-	-	-	M	-	-	-	CHAP domain
CMANEAJM_03206	1.58e-302	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
CMANEAJM_03207	0.0	traE	-	-	U	-	-	-	Psort location Cytoplasmic, score
CMANEAJM_03208	3.16e-152	-	-	-	-	-	-	-	-
CMANEAJM_03209	8.94e-70	-	-	-	-	-	-	-	-
CMANEAJM_03210	4.45e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
CMANEAJM_03211	2.06e-104	-	-	-	-	-	-	-	-
CMANEAJM_03213	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
CMANEAJM_03214	1.69e-37	-	-	-	-	-	-	-	-
CMANEAJM_03215	4.21e-55	-	-	-	-	-	-	-	-
CMANEAJM_03216	1.46e-90	-	-	-	S	-	-	-	protein conserved in bacteria
CMANEAJM_03217	1.05e-36	-	-	-	-	-	-	-	-
CMANEAJM_03218	2.44e-50	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_03219	4.9e-39	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_03221	1.57e-118	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
CMANEAJM_03222	3.05e-174	-	-	-	D	-	-	-	Cellulose biosynthesis protein BcsQ
CMANEAJM_03224	2.83e-26	-	-	-	-	-	-	-	-
CMANEAJM_03225	6.58e-33	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
CMANEAJM_03226	2.28e-248	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03227	2.39e-46	-	-	-	O	-	-	-	OsmC-like protein
CMANEAJM_03228	6.54e-54	-	-	-	O	-	-	-	OsmC-like protein
CMANEAJM_03229	3.12e-87	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
CMANEAJM_03231	1.58e-204	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
CMANEAJM_03232	4.6e-60	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CMANEAJM_03234	1.7e-127	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
CMANEAJM_03235	9.84e-174	trxB	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Glucose inhibited division protein A
CMANEAJM_03236	7.84e-29	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
CMANEAJM_03237	4e-98	M1-798	-	-	K	-	-	-	Rhodanese Homology Domain
CMANEAJM_03238	2.29e-290	-	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolases family 32
CMANEAJM_03239	1.16e-49	-	-	-	-	-	-	-	-
CMANEAJM_03240	2.31e-153	levD	-	-	G	ko:K02771	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
CMANEAJM_03241	3.51e-177	levC	-	-	M	ko:K02795	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
CMANEAJM_03242	2.01e-103	-	2.7.1.191	-	G	ko:K02794	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
CMANEAJM_03244	4.72e-34	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
CMANEAJM_03245	7.51e-282	-	-	-	K	-	-	-	Sigma-54 interaction domain
CMANEAJM_03246	2.37e-33	-	-	-	K	-	-	-	Sigma-54 interaction domain
CMANEAJM_03247	4.63e-123	-	-	-	L	-	-	-	Resolvase, N terminal domain
CMANEAJM_03248	1.6e-45	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03249	0.0	-	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
CMANEAJM_03250	2.16e-256	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
CMANEAJM_03251	6.58e-199	add	3.5.4.2, 3.5.4.4	-	F	ko:K01488,ko:K21053	ko00230,ko01100,ko05340,map00230,map01100,map05340	ko00000,ko00001,ko01000	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CMANEAJM_03252	7.03e-06	-	-	-	-	-	-	-	-
CMANEAJM_03253	1.44e-39	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
CMANEAJM_03254	1.67e-236	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CMANEAJM_03255	8.69e-34	-	-	-	-	-	-	-	-
CMANEAJM_03256	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CMANEAJM_03257	2e-85	-	-	-	-	-	-	-	-
CMANEAJM_03258	1.95e-185	-	-	-	-	-	-	-	-
CMANEAJM_03259	1.8e-71	-	-	-	-	-	-	-	-
CMANEAJM_03260	2.62e-61	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
CMANEAJM_03261	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CMANEAJM_03262	2.33e-132	-	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CMANEAJM_03263	7.9e-108	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
CMANEAJM_03264	3.18e-45	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMANEAJM_03265	8.95e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03266	2.75e-33	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
CMANEAJM_03267	1.69e-191	-	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMANEAJM_03268	2.05e-50	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMANEAJM_03269	5.19e-135	-	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
CMANEAJM_03270	1.07e-170	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
CMANEAJM_03271	1.61e-122	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
CMANEAJM_03272	7.83e-127	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
CMANEAJM_03273	8.24e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03274	4.3e-164	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	Transporter
CMANEAJM_03275	5.93e-237	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
CMANEAJM_03276	5.16e-308	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
CMANEAJM_03277	6.96e-20	-	-	-	S	-	-	-	Transglycosylase associated protein
CMANEAJM_03279	1.06e-143	-	-	-	KT	-	-	-	Purine catabolism regulatory protein-like family
CMANEAJM_03280	9.28e-209	-	-	-	F	ko:K10974	-	ko00000,ko02000	Permease for cytosine/purines, uracil, thiamine, allantoin
CMANEAJM_03281	6.42e-205	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
CMANEAJM_03282	5.32e-255	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase N-terminal region
CMANEAJM_03283	1.91e-280	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
CMANEAJM_03284	8.83e-117	-	-	-	-	-	-	-	-
CMANEAJM_03285	4.12e-32	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_03286	8.83e-282	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
CMANEAJM_03287	7.25e-111	-	-	-	S	-	-	-	Membrane
CMANEAJM_03288	1.96e-225	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03289	5.62e-24	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
CMANEAJM_03290	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CMANEAJM_03292	9.98e-68	repA	-	-	S	-	-	-	Replication initiator protein A
CMANEAJM_03293	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
CMANEAJM_03294	1.51e-85	-	-	-	-	-	-	-	-
CMANEAJM_03295	4.5e-50	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	Natural resistance-associated macrophage protein
CMANEAJM_03296	5.98e-212	-	-	-	P	-	-	-	CorA-like Mg2+ transporter protein
CMANEAJM_03297	6.61e-61	-	-	-	L	-	-	-	Transposase DDE domain
CMANEAJM_03298	7.97e-33	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
CMANEAJM_03299	4.93e-54	-	-	-	-	-	-	-	-
CMANEAJM_03300	1.1e-33	-	-	-	-	-	-	-	-
CMANEAJM_03301	6.26e-220	traA	-	-	L	-	-	-	MobA MobL family protein
CMANEAJM_03302	6.33e-225	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
CMANEAJM_03304	4.33e-226	arsB	-	-	U	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CMANEAJM_03305	4.68e-43	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
CMANEAJM_03306	3.81e-136	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMANEAJM_03307	4.95e-34	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
CMANEAJM_03308	9.87e-245	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
CMANEAJM_03309	1.32e-43	-	-	-	-	-	-	-	-
CMANEAJM_03310	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
CMANEAJM_03311	1.96e-213	-	-	-	L	-	-	-	MobA MobL family protein
CMANEAJM_03312	2.68e-229	-	-	-	L	-	-	-	MobA MobL family protein
CMANEAJM_03313	1.69e-37	-	-	-	-	-	-	-	-
CMANEAJM_03314	5.98e-55	-	-	-	-	-	-	-	-
CMANEAJM_03315	3.33e-107	-	-	-	-	-	-	-	-
CMANEAJM_03316	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
CMANEAJM_03317	1.42e-26	repA	-	-	S	-	-	-	Replication initiator protein A
CMANEAJM_03318	4.87e-50	-	-	-	L	-	-	-	Transposase
CMANEAJM_03319	2.27e-114	-	-	-	L	-	-	-	Transposase
CMANEAJM_03320	1.92e-48	-	-	-	L	-	-	-	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMANEAJM_03321	2.39e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
CMANEAJM_03323	2.8e-44	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03325	3.41e-160	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
CMANEAJM_03326	1.63e-122	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMANEAJM_03327	3.52e-151	-	-	-	K	-	-	-	Transcriptional regulator
CMANEAJM_03328	4.83e-252	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system, permease component
CMANEAJM_03329	8.66e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
CMANEAJM_03330	2.59e-77	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
CMANEAJM_03331	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CMANEAJM_03332	7.17e-57	-	-	-	L	-	-	-	Integrase
CMANEAJM_03333	2.27e-114	-	-	-	L	-	-	-	Transposase
CMANEAJM_03334	4.87e-50	-	-	-	L	-	-	-	Transposase
CMANEAJM_03335	5.31e-71	-	-	-	L	-	-	-	Integrase
CMANEAJM_03336	4e-73	-	-	-	-	-	-	-	-
CMANEAJM_03338	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
CMANEAJM_03339	1.15e-183	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
CMANEAJM_03342	1.92e-71	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
CMANEAJM_03343	3.27e-53	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
CMANEAJM_03344	1.67e-25	-	-	-	-	-	-	-	-
CMANEAJM_03345	4.79e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
CMANEAJM_03346	9.47e-43	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
CMANEAJM_03347	1.04e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
CMANEAJM_03348	0.0	ybeC	-	-	E	-	-	-	amino acid
CMANEAJM_03349	7.04e-247	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
CMANEAJM_03350	3.89e-132	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
CMANEAJM_03351	1.76e-39	-	-	-	-	-	-	-	-
CMANEAJM_03352	1.66e-34	-	-	-	-	-	-	-	-
CMANEAJM_03353	1.51e-84	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
CMANEAJM_03354	3.94e-31	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
CMANEAJM_03355	1.33e-46	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
CMANEAJM_03356	5.91e-39	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_03357	1.18e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_03358	3.97e-20	-	-	-	K	-	-	-	Helix-turn-helix domain
CMANEAJM_03360	7.95e-78	-	-	-	S	-	-	-	Protein of unknown function (DUF2992)
CMANEAJM_03361	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMANEAJM_03362	1.83e-58	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
CMANEAJM_03363	8.53e-136	-	-	-	L	-	-	-	Integrase
CMANEAJM_03364	1.24e-39	-	-	-	-	-	-	-	-
CMANEAJM_03367	5.98e-111	-	-	-	-	-	-	-	-
CMANEAJM_03368	1.22e-81	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CMANEAJM_03369	2.18e-18	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
CMANEAJM_03370	6.36e-145	M1-798	-	-	K	-	-	-	Rhodanese Homology Domain
CMANEAJM_03371	2.51e-61	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
CMANEAJM_03372	1.94e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
CMANEAJM_03373	3.05e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
CMANEAJM_03374	5.17e-16	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
CMANEAJM_03375	4.47e-229	trxB	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Glucose inhibited division protein A
CMANEAJM_03376	2.82e-153	frnE	5.3.4.1	-	Q	ko:K01829	-	ko00000,ko01000	dithiol-disulfide isomerase involved in polyketide biosynthesis
CMANEAJM_03378	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulphide oxidoreductase
CMANEAJM_03379	2.59e-77	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
CMANEAJM_03380	2.63e-58	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CMANEAJM_03381	5.94e-127	-	-	-	L	-	-	-	Integrase
CMANEAJM_03382	3.91e-82	-	-	-	-	-	-	-	-
CMANEAJM_03384	2.06e-103	-	-	-	L	-	-	-	Integrase
CMANEAJM_03385	3.5e-220	-	-	-	L	-	-	-	Initiator Replication protein
CMANEAJM_03386	6.86e-81	-	-	-	-	-	-	-	-
CMANEAJM_03387	3.45e-28	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_03388	4.68e-67	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
CMANEAJM_03389	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMANEAJM_03390	2.17e-08	-	-	-	L	-	-	-	Integrase
CMANEAJM_03391	2.69e-226	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
CMANEAJM_03393	2.06e-103	-	-	-	L	-	-	-	Integrase
CMANEAJM_03394	3.5e-220	-	-	-	L	-	-	-	Initiator Replication protein
CMANEAJM_03395	6.86e-81	-	-	-	-	-	-	-	-
CMANEAJM_03396	3.45e-28	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
CMANEAJM_03397	4.68e-67	-	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	Bacterial toxin of type II toxin-antitoxin system, YafQ
CMANEAJM_03398	8.83e-57	-	-	-	S	ko:K07473	-	ko00000,ko02048	RelB antitoxin
CMANEAJM_03399	2.17e-08	-	-	-	L	-	-	-	Integrase
CMANEAJM_03400	1.35e-73	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
CMANEAJM_03401	5.43e-38	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
CMANEAJM_03402	2.18e-138	-	-	-	L	-	-	-	Integrase
CMANEAJM_03403	1.68e-78	-	-	-	-	-	-	-	-
CMANEAJM_03404	4.18e-39	-	-	-	-	-	-	-	-
CMANEAJM_03405	9.05e-207	-	-	-	L	-	-	-	Initiator Replication protein
CMANEAJM_03406	6.15e-104	-	-	-	-	-	-	-	-
CMANEAJM_03407	1.18e-05	-	-	-	K	-	-	-	SIR2-like domain
CMANEAJM_03408	2.56e-76	-	-	-	L	ko:K07483,ko:K07497	-	ko00000	Helix-turn-helix domain
CMANEAJM_03409	7.26e-120	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
CMANEAJM_03410	9.08e-201	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
CMANEAJM_03411	6.04e-135	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
CMANEAJM_03412	1.5e-238	rafB	-	-	P	ko:K02532	-	ko00000,ko02000	LacY proton/sugar symporter
CMANEAJM_03413	1.16e-228	-	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
CMANEAJM_03414	2.59e-77	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
CMANEAJM_03415	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
CMANEAJM_03416	1.87e-139	-	-	-	L	-	-	-	Integrase
CMANEAJM_03417	2.58e-82	-	-	-	-	-	-	-	-
CMANEAJM_03418	2.94e-39	-	-	-	-	-	-	-	-
CMANEAJM_03419	2.41e-200	-	-	-	L	-	-	-	Initiator Replication protein
CMANEAJM_03420	3.35e-59	-	-	-	-	-	-	-	-
CMANEAJM_03422	4.45e-90	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	Adenine specific DNA methylase Mod
CMANEAJM_03423	3.85e-05	-	2.1.1.72	-	L	ko:K07316	-	ko00000,ko01000,ko02048	PFAM DNA methylase N-4 N-6
CMANEAJM_03424	6.49e-43	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
CMANEAJM_03425	4.01e-226	XK27_03440	3.1.21.5	-	L	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit