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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MKNPMADF_00001	2.01e-266	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	alcohol dehydrogenase
MKNPMADF_00002	7.96e-19	-	-	-	-	-	-	-	-
MKNPMADF_00003	0.0	cckA	2.7.13.3	-	T	ko:K02482	-	ko00000,ko01000,ko01001,ko02022	GAF domain
MKNPMADF_00004	0.0	-	-	-	T	ko:K02481	-	ko00000,ko02022	Sigma-54 interaction domain
MKNPMADF_00005	9.71e-253	adhA	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MKNPMADF_00006	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKNPMADF_00007	3.26e-226	-	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNPMADF_00009	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
MKNPMADF_00010	6.14e-147	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKNPMADF_00011	9.77e-71	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_00012	8.67e-233	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MKNPMADF_00013	3.66e-188	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
MKNPMADF_00014	1.21e-59	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MKNPMADF_00015	1.28e-172	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
MKNPMADF_00016	9.86e-54	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
MKNPMADF_00017	3.17e-200	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKNPMADF_00018	3.04e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
MKNPMADF_00019	2.76e-221	-	-	-	S	-	-	-	NurA
MKNPMADF_00020	0.0	-	-	-	S	ko:K06915	-	ko00000	Domain of unknown function DUF87
MKNPMADF_00021	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKNPMADF_00022	1.34e-101	-	-	-	K	-	-	-	DNA-binding transcription factor activity
MKNPMADF_00023	5.54e-236	pelB	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Amb_all
MKNPMADF_00025	0.0	-	-	-	S	-	-	-	ABC transporter
MKNPMADF_00026	9.74e-146	-	-	-	T	-	-	-	protein histidine kinase activity
MKNPMADF_00027	0.0	-	-	-	S	-	-	-	Protein of unknown function (DUF3298)
MKNPMADF_00028	8.69e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
MKNPMADF_00029	7.33e-267	yabE	-	-	T	-	-	-	protein conserved in bacteria
MKNPMADF_00030	5.18e-130	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKNPMADF_00031	2.4e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKNPMADF_00032	2.53e-208	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
MKNPMADF_00033	4.02e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_00034	1.8e-34	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
MKNPMADF_00035	1.85e-208	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKNPMADF_00036	1.56e-190	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MKNPMADF_00037	4.06e-81	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
MKNPMADF_00038	2.26e-64	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MKNPMADF_00039	0.0	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKNPMADF_00040	7.02e-218	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKNPMADF_00041	1.21e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MKNPMADF_00042	2.48e-130	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKNPMADF_00043	7.09e-51	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
MKNPMADF_00044	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKNPMADF_00045	6.61e-123	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
MKNPMADF_00046	3.57e-131	-	-	-	S	-	-	-	Yip1 domain
MKNPMADF_00047	1.43e-252	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKNPMADF_00048	8.06e-115	-	-	-	S	-	-	-	Yip1 domain
MKNPMADF_00049	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKNPMADF_00050	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MKNPMADF_00051	1.89e-43	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MKNPMADF_00052	8.62e-146	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
MKNPMADF_00053	7.93e-222	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNPMADF_00054	5.14e-111	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_00055	8.86e-250	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MKNPMADF_00056	3.17e-131	-	-	-	S	-	-	-	SNARE associated Golgi protein
MKNPMADF_00057	6.51e-69	yabP	-	-	S	-	-	-	Sporulation protein YabP
MKNPMADF_00058	4.43e-93	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
MKNPMADF_00059	2.87e-79	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MKNPMADF_00060	8.65e-92	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MKNPMADF_00062	3.42e-283	citM	-	-	C	ko:K03300	-	ko00000	Citrate transporter
MKNPMADF_00063	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
MKNPMADF_00064	2.19e-165	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
MKNPMADF_00065	6.67e-223	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MKNPMADF_00066	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKNPMADF_00067	9.01e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
MKNPMADF_00068	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKNPMADF_00069	3.69e-183	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MKNPMADF_00070	1.63e-201	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKNPMADF_00071	2.28e-221	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MKNPMADF_00072	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKNPMADF_00073	3.61e-138	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
MKNPMADF_00074	1.82e-190	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
MKNPMADF_00075	5.86e-189	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MKNPMADF_00076	4.26e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKNPMADF_00077	4.18e-118	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MKNPMADF_00078	5.32e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKNPMADF_00079	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MKNPMADF_00089	2.04e-19	-	-	-	-	-	-	-	-
MKNPMADF_00090	4.79e-95	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MKNPMADF_00091	1.2e-121	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
MKNPMADF_00092	1.88e-250	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MKNPMADF_00093	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
MKNPMADF_00094	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKNPMADF_00095	4.09e-249	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MKNPMADF_00096	1.38e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
MKNPMADF_00097	5.82e-153	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MKNPMADF_00098	3.66e-108	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MKNPMADF_00099	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKNPMADF_00100	1.98e-156	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
MKNPMADF_00101	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MKNPMADF_00102	8.52e-91	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKNPMADF_00103	3.82e-184	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKNPMADF_00104	5.28e-111	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
MKNPMADF_00105	9.77e-152	comX	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MKNPMADF_00106	2.37e-34	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKNPMADF_00107	1.83e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MKNPMADF_00108	1.19e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKNPMADF_00109	4.64e-160	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKNPMADF_00110	8.48e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKNPMADF_00111	1.27e-69	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKNPMADF_00112	2.91e-148	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
MKNPMADF_00113	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNPMADF_00114	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNPMADF_00115	3.72e-47	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
MKNPMADF_00116	4.33e-95	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKNPMADF_00117	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKNPMADF_00118	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKNPMADF_00119	6.72e-286	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKNPMADF_00120	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MKNPMADF_00121	9.49e-143	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKNPMADF_00122	2.22e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MKNPMADF_00123	1.38e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKNPMADF_00124	5.09e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKNPMADF_00125	1.53e-61	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKNPMADF_00126	8.5e-72	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKNPMADF_00127	1.76e-154	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKNPMADF_00128	3.79e-101	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKNPMADF_00129	5.12e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MKNPMADF_00130	2.17e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKNPMADF_00131	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKNPMADF_00132	7.7e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKNPMADF_00133	2.21e-121	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKNPMADF_00134	1.54e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKNPMADF_00135	1.83e-124	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKNPMADF_00136	8.96e-79	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKNPMADF_00137	1.59e-110	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKNPMADF_00138	7.06e-36	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MKNPMADF_00139	9.26e-98	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKNPMADF_00140	1.39e-296	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKNPMADF_00141	7.76e-152	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKNPMADF_00142	1.1e-180	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKNPMADF_00143	4.15e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKNPMADF_00144	5.99e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MKNPMADF_00145	8.92e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKNPMADF_00146	4.05e-85	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKNPMADF_00147	4.06e-216	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNPMADF_00148	1.49e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MKNPMADF_00149	1.57e-201	cbiO	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNPMADF_00150	3.48e-185	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNPMADF_00151	1.77e-169	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNPMADF_00152	6.89e-186	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKNPMADF_00153	2.77e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKNPMADF_00154	4.45e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MKNPMADF_00155	1.54e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2975)
MKNPMADF_00156	1.26e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_00158	1.05e-90	ykkB	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_00159	4.26e-104	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
MKNPMADF_00160	1.75e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKNPMADF_00161	2.12e-189	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
MKNPMADF_00162	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00163	2.18e-245	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MKNPMADF_00164	2.62e-210	-	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MKNPMADF_00165	4.55e-31	-	-	-	K	-	-	-	MarR family transcriptional regulator
MKNPMADF_00166	2.04e-28	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00167	6.63e-96	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKNPMADF_00168	1.67e-40	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PFAM Phosphotransferase system, lactose cellobiose-specific IIB subunit
MKNPMADF_00169	8.66e-223	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNPMADF_00170	3.88e-91	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MKNPMADF_00171	4.89e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF4127)
MKNPMADF_00172	3.18e-119	-	-	-	K	-	-	-	transcriptional regulator, RpiR family
MKNPMADF_00173	6.68e-96	gerD	-	-	S	ko:K06294	-	ko00000	Spore gernimation protein
MKNPMADF_00174	8e-130	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
MKNPMADF_00175	8.38e-183	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
MKNPMADF_00176	5.74e-46	-	-	-	-	-	-	-	-
MKNPMADF_00179	8.34e-221	-	-	-	L	-	-	-	Endonuclease/Exonuclease/phosphatase family
MKNPMADF_00180	7.21e-101	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_00183	1.96e-110	-	2.7.1.190	-	S	ko:K17910	-	ko00000,ko01000,ko01504	Protein of unknown function (DUF1679)
MKNPMADF_00184	4.39e-149	-	-	-	O	-	-	-	Sap, sulfolipid-1-addressing protein
MKNPMADF_00185	5.18e-94	-	-	-	-	-	-	-	-
MKNPMADF_00186	1.82e-183	-	-	-	K	-	-	-	MerR family transcriptional regulator
MKNPMADF_00187	9.48e-204	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKNPMADF_00188	2.78e-241	-	-	-	M	-	-	-	Mandelate racemase / muconate lactonizing enzyme, C-terminal domain
MKNPMADF_00189	5.16e-174	-	-	-	KT	-	-	-	Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding
MKNPMADF_00190	1.94e-244	-	-	-	EGP	-	-	-	MFS/sugar transport protein
MKNPMADF_00191	1.24e-148	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
MKNPMADF_00192	8.76e-67	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKNPMADF_00193	2.81e-74	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
MKNPMADF_00194	1.51e-34	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix domain
MKNPMADF_00195	2.13e-96	-	-	-	-	-	-	-	-
MKNPMADF_00196	6.41e-28	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_00197	9.07e-13	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_00198	1.36e-243	bdhA	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
MKNPMADF_00199	6.66e-135	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
MKNPMADF_00200	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_00201	1.22e-09	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKNPMADF_00203	1.62e-11	-	-	-	-	-	-	-	-
MKNPMADF_00210	5.59e-128	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKNPMADF_00211	2.31e-155	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MKNPMADF_00212	3.79e-185	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKNPMADF_00213	4.66e-278	ybbR	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_00214	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKNPMADF_00216	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKNPMADF_00217	5.23e-218	-	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MKNPMADF_00218	0.0	-	-	-	G	-	-	-	isomerase
MKNPMADF_00219	1.23e-191	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	COG3959 Transketolase, N-terminal subunit
MKNPMADF_00220	1.4e-213	-	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transketolase, pyrimidine binding domain
MKNPMADF_00221	0.0	glpK3	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	FGGY family of carbohydrate kinases, C-terminal domain
MKNPMADF_00222	2.3e-283	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00223	5.12e-302	-	-	-	G	-	-	-	Protein of unknown function (DUF4038)
MKNPMADF_00224	6.38e-96	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MKNPMADF_00225	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKNPMADF_00226	3.64e-185	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00227	7.58e-217	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MKNPMADF_00228	8.63e-254	-	-	-	V	-	-	-	Beta-lactamase
MKNPMADF_00230	0.0	-	-	-	S	-	-	-	Aminoglycoside phosphotransferase
MKNPMADF_00231	1.43e-96	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MKNPMADF_00232	3.86e-282	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MKNPMADF_00233	3.67e-180	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_00234	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKNPMADF_00235	5.03e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MKNPMADF_00236	8.76e-238	-	-	-	T	-	-	-	Histidine kinase-like ATPases
MKNPMADF_00237	1e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_00238	1.21e-288	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MKNPMADF_00239	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKNPMADF_00240	7.3e-169	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_00241	3.47e-73	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
MKNPMADF_00242	3.17e-200	CcmA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_00243	1.94e-119	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKNPMADF_00244	2.29e-224	-	6.1.1.17	-	J	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKNPMADF_00245	7.93e-196	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
MKNPMADF_00246	0.0	mecR1	-	-	KTV	ko:K02172,ko:K02547	ko01501,map01501	ko00000,ko00001,ko00002,ko01002,ko01504	BlaR1 peptidase M56
MKNPMADF_00247	2.61e-83	blaI	-	-	K	ko:K02171,ko:K02546	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Penicillinase repressor
MKNPMADF_00248	1.01e-180	-	-	-	H	ko:K17882	-	ko00000,ko01000,ko01504	KNTase C-terminal domain
MKNPMADF_00249	1.57e-83	-	-	-	K	ko:K21903	-	ko00000,ko03000	transcriptional
MKNPMADF_00250	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MKNPMADF_00251	3.92e-246	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
MKNPMADF_00252	2.6e-107	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKNPMADF_00253	4.47e-103	-	-	-	-	-	-	-	-
MKNPMADF_00254	5.94e-175	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKNPMADF_00255	8.67e-230	-	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MKNPMADF_00256	4.76e-146	-	-	-	Q	-	-	-	SAM-dependent methyltransferase
MKNPMADF_00257	2.15e-180	-	-	-	EG	-	-	-	EamA-like transporter family
MKNPMADF_00258	4.64e-166	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKNPMADF_00259	3.88e-136	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_00260	5.53e-84	-	-	-	-	-	-	-	-
MKNPMADF_00261	1.12e-89	-	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MKNPMADF_00262	4.73e-146	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MKNPMADF_00263	3.68e-107	-	2.3.1.128	-	J	ko:K03789,ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKNPMADF_00264	0.0	siaT_4	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
MKNPMADF_00265	3.34e-67	-	-	-	S	-	-	-	Domain of unknown function (DUF1850)
MKNPMADF_00266	1.01e-151	-	-	-	S	ko:K07080	-	ko00000	NMT1-like family
MKNPMADF_00267	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MKNPMADF_00268	5.23e-151	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MKNPMADF_00269	5.54e-210	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
MKNPMADF_00270	7.06e-272	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MKNPMADF_00271	5.09e-124	flaR	-	-	F	-	-	-	topology modulation protein
MKNPMADF_00273	4.11e-11	-	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MKNPMADF_00274	2.62e-111	ftnA	1.16.3.2	-	P	ko:K02217	-	ko00000,ko01000	Iron-storage protein
MKNPMADF_00275	1.99e-216	yueF	-	-	S	-	-	-	transporter activity
MKNPMADF_00276	0.0	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKNPMADF_00277	9.04e-130	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKNPMADF_00278	0.0	-	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
MKNPMADF_00279	4.09e-276	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MKNPMADF_00280	8.48e-106	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_00281	5.04e-233	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
MKNPMADF_00282	5.31e-217	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKNPMADF_00283	4.59e-173	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_00284	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MKNPMADF_00285	2.19e-188	murR	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00286	1.19e-232	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
MKNPMADF_00287	1.08e-303	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
MKNPMADF_00288	3.28e-213	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MKNPMADF_00290	0.0	-	-	-	K	-	-	-	Propionate catabolism activator
MKNPMADF_00291	1.55e-195	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKNPMADF_00292	5.27e-299	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00293	6.69e-241	yleB	4.2.1.126	-	S	ko:K07106,ko:K09963	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Bacterial protein of unknown function (DUF871)
MKNPMADF_00294	8.01e-229	purR15	-	-	K	ko:K02529	-	ko00000,ko03000	Bacterial regulatory proteins, lacI family
MKNPMADF_00295	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKNPMADF_00296	1.29e-191	-	-	-	GK	-	-	-	ROK family
MKNPMADF_00297	2.86e-193	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00298	5.44e-207	-	-	-	P	ko:K02026,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKNPMADF_00299	6.59e-278	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00300	2.42e-189	manA3	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Endoglucanase
MKNPMADF_00301	8.39e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MKNPMADF_00302	1.51e-17	-	-	-	-	-	-	-	-
MKNPMADF_00303	1.35e-126	-	-	-	S	-	-	-	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MKNPMADF_00304	9.12e-174	-	-	-	C	-	-	-	alcohol dehydrogenase
MKNPMADF_00305	4.47e-99	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00306	3.23e-70	fdx5	-	-	C	-	-	-	2Fe-2S iron-sulfur cluster binding domain
MKNPMADF_00307	1.06e-28	-	-	-	-	-	-	-	-
MKNPMADF_00308	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
MKNPMADF_00309	1.89e-275	adhB	1.1.1.1, 1.1.1.202	-	C	ko:K00001,ko:K00086	ko00010,ko00071,ko00350,ko00561,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00561,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MKNPMADF_00310	3.31e-284	-	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
MKNPMADF_00311	7.35e-221	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
MKNPMADF_00312	2.98e-252	-	-	-	C	ko:K19954	-	ko00000,ko01000	alcohol dehydrogenase
MKNPMADF_00313	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_00314	0.0	-	-	-	EG	ko:K06295	-	ko00000	Bacillus/Clostridium GerA spore germination protein
MKNPMADF_00315	6.42e-84	-	-	-	-	-	-	-	-
MKNPMADF_00316	3.43e-114	ectA	2.3.1.178	-	K	ko:K06718	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	L-2,4-diaminobutyric acid acetyltransferase
MKNPMADF_00317	7.39e-312	ectB	2.6.1.76	-	E	ko:K00836	ko00260,ko01100,ko01120,ko01210,ko01230,map00260,map01100,map01120,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKNPMADF_00318	1.59e-99	ectC	4.2.1.108	-	S	ko:K06720	ko00260,ko01100,ko01120,map00260,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant
MKNPMADF_00319	0.0	-	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
MKNPMADF_00320	9.78e-188	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_00321	9.2e-210	-	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKNPMADF_00322	6.89e-190	-	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_00323	1.82e-246	-	3.6.3.20	-	P	ko:K05816	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_00326	1.85e-262	-	-	-	KLT	-	-	-	Protein kinase domain
MKNPMADF_00329	6.9e-96	-	-	-	H	-	-	-	Tellurite resistance protein TehB
MKNPMADF_00330	3.92e-64	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKNPMADF_00332	0.0	alkK	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKNPMADF_00333	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
MKNPMADF_00334	1.65e-256	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MKNPMADF_00335	7.03e-177	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNPMADF_00336	1.41e-241	yneE	-	-	K	-	-	-	Arabinose-binding domain of AraC transcription regulator, N-term
MKNPMADF_00338	1.85e-96	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MKNPMADF_00339	1.39e-297	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MKNPMADF_00340	0.0	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
MKNPMADF_00341	4.27e-253	ugpC	3.6.3.20	-	P	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_00342	2.71e-207	ugpA	-	-	G	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
MKNPMADF_00343	1.36e-177	ugpE	-	-	P	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter permease
MKNPMADF_00344	4.49e-300	ugpB	-	-	G	ko:K02027,ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycerol-3-phosphate ABC transporter substrate-binding protein
MKNPMADF_00345	1.05e-175	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKNPMADF_00346	5.53e-266	-	-	-	EGP	ko:K08162	-	ko00000,ko02000	Major Facilitator Superfamily
MKNPMADF_00347	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00348	1.83e-188	-	-	-	G	-	-	-	Haloacid dehalogenase-like hydrolase
MKNPMADF_00349	4.85e-119	-	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKNPMADF_00350	1.28e-224	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00351	1.02e-198	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKNPMADF_00352	1.78e-153	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKNPMADF_00353	5.39e-222	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_00354	2.1e-247	-	1.1.1.361	-	S	ko:K18652	-	ko00000,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_00355	1.72e-129	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
MKNPMADF_00357	1.61e-242	-	-	-	-	-	-	-	-
MKNPMADF_00358	4.41e-179	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_00359	1.43e-184	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MKNPMADF_00360	2.62e-87	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNPMADF_00361	7.59e-214	hutG	3.5.3.8	-	E	ko:K01479	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MKNPMADF_00362	0.0	-	-	-	E	-	-	-	amino acid
MKNPMADF_00363	1.01e-225	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00364	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
MKNPMADF_00365	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
MKNPMADF_00366	1.87e-68	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
MKNPMADF_00367	6.97e-284	-	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
MKNPMADF_00368	1.61e-188	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00369	5.8e-293	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_00370	6.88e-277	-	-	-	EM	-	-	-	Protein of unknown function (DUF993)
MKNPMADF_00371	4.71e-199	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_00372	1.21e-267	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_00373	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_00374	2.58e-253	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKNPMADF_00375	9.51e-316	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00376	5.85e-225	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00377	1.15e-198	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00378	4.05e-246	-	-	-	I	-	-	-	Acyltransferase family
MKNPMADF_00379	3.16e-296	ciaH	2.7.13.3	-	T	ko:K14982	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MKNPMADF_00380	5.64e-152	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_00381	1.33e-162	-	-	-	S	-	-	-	L-2-amino-thiazoline-4-carboxylic acid hydrolase
MKNPMADF_00382	0.0	yesW	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
MKNPMADF_00383	7.74e-299	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00384	6.96e-195	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00385	1.46e-201	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00386	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
MKNPMADF_00387	1.08e-306	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00388	5.07e-204	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00389	6.38e-196	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00390	5.32e-131	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKNPMADF_00391	3.48e-216	M1-640	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00392	1.21e-209	rhaR1	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00393	6.56e-180	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
MKNPMADF_00394	7.7e-275	egsA	1.1.1.261	-	C	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MKNPMADF_00395	5.92e-174	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MKNPMADF_00396	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
MKNPMADF_00397	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MKNPMADF_00398	4.61e-251	chvE	-	-	G	ko:K10546	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_00399	0.0	araG	3.6.3.17	-	G	ko:K10548	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MKNPMADF_00400	6.41e-247	araH	-	-	G	ko:K10544,ko:K10547	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKNPMADF_00401	0.0	melA7	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MKNPMADF_00402	1.2e-64	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKNPMADF_00404	9.58e-101	-	-	-	S	-	-	-	Putative small multi-drug export protein
MKNPMADF_00405	2.4e-142	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MKNPMADF_00406	6.72e-228	-	-	-	KTV	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
MKNPMADF_00407	2.37e-62	ykkD_1	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKNPMADF_00408	1.69e-77	ykkC_1	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
MKNPMADF_00409	3.47e-129	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00410	6.48e-303	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKNPMADF_00411	1.95e-174	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKNPMADF_00412	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_00413	1.15e-198	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MKNPMADF_00414	9.35e-228	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MKNPMADF_00415	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MKNPMADF_00416	7.11e-225	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MKNPMADF_00417	5.8e-248	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MKNPMADF_00418	4.1e-126	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MKNPMADF_00419	2.58e-197	iolJ	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MKNPMADF_00420	2.13e-231	-	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_00421	0.0	-	-	-	S	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKNPMADF_00422	1.66e-305	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	O-acetylhomoserine
MKNPMADF_00423	2.95e-77	-	-	-	S	ko:K06940	-	ko00000	Putative zinc- or iron-chelating domain
MKNPMADF_00424	7.02e-182	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00425	3.71e-209	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00426	1.83e-315	-	-	-	G	ko:K02027,ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00428	6.65e-204	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00429	4.7e-238	-	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MKNPMADF_00430	3.89e-241	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
MKNPMADF_00431	6.3e-105	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_00432	8.79e-284	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
MKNPMADF_00433	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MKNPMADF_00434	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MKNPMADF_00435	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
MKNPMADF_00436	4.35e-204	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MKNPMADF_00437	7.46e-101	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNPMADF_00438	6.25e-63	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_00439	6.11e-237	fruA2	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
MKNPMADF_00440	6.74e-119	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
MKNPMADF_00442	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKNPMADF_00443	1.2e-203	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MKNPMADF_00444	1.36e-132	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MKNPMADF_00445	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
MKNPMADF_00446	1.65e-299	-	-	-	E	-	-	-	Acyclic terpene utilisation family protein AtuA
MKNPMADF_00447	1.96e-65	-	-	-	-	-	-	-	-
MKNPMADF_00448	9e-279	-	-	-	C	ko:K03300	-	ko00000	Citrate transporter
MKNPMADF_00449	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKNPMADF_00450	7.21e-300	-	-	-	V	-	-	-	MatE
MKNPMADF_00451	1.2e-50	-	-	-	-	-	-	-	-
MKNPMADF_00452	2.69e-128	-	-	-	S	-	-	-	Tetratricopeptide repeat
MKNPMADF_00453	4.1e-87	-	-	-	F	-	-	-	NUDIX domain
MKNPMADF_00454	1.04e-136	-	-	-	-	-	-	-	-
MKNPMADF_00455	1.57e-147	-	-	-	-	-	-	-	-
MKNPMADF_00456	0.0	-	-	-	-	-	-	-	-
MKNPMADF_00457	1e-69	-	-	-	-	-	-	-	-
MKNPMADF_00458	1.08e-244	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	mannonate dehydratase activity
MKNPMADF_00459	3.55e-234	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MKNPMADF_00460	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
MKNPMADF_00461	1.48e-103	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
MKNPMADF_00462	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_00463	7.93e-219	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
MKNPMADF_00464	1e-154	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MKNPMADF_00465	3.89e-147	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MKNPMADF_00466	6.79e-257	yycB1	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MKNPMADF_00467	4.14e-81	-	-	-	F	-	-	-	Cytidine and deoxycytidylate deaminase zinc-binding region
MKNPMADF_00468	9.96e-95	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00469	9.88e-184	-	3.4.16.4	-	V	ko:K01286	-	ko00000,ko01000	Beta-lactamase
MKNPMADF_00470	8.46e-160	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
MKNPMADF_00471	2.5e-58	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00472	3.41e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNPMADF_00473	2.1e-63	celC	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00474	0.0	gmuD	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKNPMADF_00475	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MKNPMADF_00476	7.01e-78	-	-	-	K	-	-	-	TetR family transcriptional regulator
MKNPMADF_00477	4.18e-135	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_00478	1.27e-105	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
MKNPMADF_00479	1.74e-110	-	-	-	-	-	-	-	-
MKNPMADF_00480	8.17e-265	-	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MKNPMADF_00481	0.0	-	3.2.1.24	GH38	G	ko:K01191	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
MKNPMADF_00482	1.25e-231	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
MKNPMADF_00483	3.85e-312	-	2.3.1.204, 3.2.1.24	GH38	G	ko:K01191,ko:K16869	ko00511,map00511	ko00000,ko00001,ko01000,ko04131	Alpha mannosidase, middle domain
MKNPMADF_00484	1.4e-236	-	-	-	S	ko:K09704	-	ko00000	Glycosyl hydrolase
MKNPMADF_00485	2.93e-13	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKNPMADF_00486	6.62e-149	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_00487	1.74e-123	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MKNPMADF_00488	1.36e-171	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00489	4.62e-170	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00490	1.26e-256	ypcG	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_00491	2.37e-89	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
MKNPMADF_00492	1.17e-205	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase (reverse transcriptase)
MKNPMADF_00493	1.91e-122	-	-	-	M	-	-	-	3D domain
MKNPMADF_00494	7.88e-278	-	-	-	JM	-	-	-	Bacterial transferase hexapeptide (six repeats)
MKNPMADF_00495	2.48e-162	frlR3	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MKNPMADF_00496	3.29e-181	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
MKNPMADF_00497	6.63e-108	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_00498	4.58e-305	ykoH	-	-	T	-	-	-	Histidine kinase
MKNPMADF_00499	1.63e-149	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKNPMADF_00500	1.58e-112	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
MKNPMADF_00501	4.65e-150	-	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Glycerate kinase family
MKNPMADF_00502	3.61e-130	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
MKNPMADF_00504	0.0	-	-	-	I	-	-	-	radical SAM domain protein
MKNPMADF_00505	0.0	-	1.3.98.3	-	H	ko:K02495	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of porphyrin-containing compound
MKNPMADF_00507	3.5e-170	yafE	-	-	Q	-	-	-	methyltransferase
MKNPMADF_00509	2.9e-114	-	-	-	S	-	-	-	Uncharacterised protein family UPF0066
MKNPMADF_00510	4.48e-279	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_00511	3.91e-124	-	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKNPMADF_00512	1.41e-214	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	GDP-mannose 4,6 dehydratase
MKNPMADF_00513	2.21e-228	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKNPMADF_00514	1.98e-197	-	-	-	-	-	-	-	-
MKNPMADF_00515	2.8e-160	-	-	GT2,GT4	M	ko:K20444	-	ko00000,ko01000,ko01005,ko02000	transferase activity, transferring glycosyl groups
MKNPMADF_00516	4.21e-213	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MKNPMADF_00517	4.41e-148	-	-	-	M	-	-	-	Glycosyl transferase family 2
MKNPMADF_00518	4.26e-292	-	1.1.1.136	-	M	ko:K13015	ko00520,map00520	ko00000,ko00001,ko01000,ko01005	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKNPMADF_00519	8.15e-250	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKNPMADF_00520	1.07e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MKNPMADF_00521	2.58e-33	-	-	-	-	-	-	-	-
MKNPMADF_00522	4.06e-306	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
MKNPMADF_00523	6.24e-119	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
MKNPMADF_00524	2.4e-155	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
MKNPMADF_00525	2.6e-208	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MKNPMADF_00526	1.62e-130	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	KDPG and KHG aldolase
MKNPMADF_00527	8.16e-289	dgoD	4.2.1.6	-	M	ko:K01684	ko00052,ko01100,ko01120,map00052,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MKNPMADF_00528	8.06e-247	gntU	-	-	EG	ko:K03299,ko:K06156	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MKNPMADF_00529	1.99e-197	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MKNPMADF_00530	1.9e-113	-	-	-	S	-	-	-	Predicted membrane protein (DUF2243)
MKNPMADF_00531	1.15e-157	-	-	-	S	ko:K02351	-	ko00000	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)
MKNPMADF_00532	3.8e-293	-	2.7.13.3	-	T	ko:K02484	-	ko00000,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
MKNPMADF_00533	9.77e-160	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_00534	2.27e-212	-	-	-	K	-	-	-	DJ-1/PfpI family
MKNPMADF_00535	1.44e-140	-	-	-	S	-	-	-	Predicted membrane protein (DUF2306)
MKNPMADF_00536	4.82e-254	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MKNPMADF_00537	1.85e-99	-	-	-	S	-	-	-	VanZ like family
MKNPMADF_00538	2.33e-142	wrbA	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
MKNPMADF_00540	8.83e-106	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MKNPMADF_00541	5.94e-164	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKNPMADF_00542	0.0	-	-	-	V	-	-	-	SNF2 family N-terminal domain
MKNPMADF_00545	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MKNPMADF_00546	1.43e-112	-	-	-	-	-	-	-	-
MKNPMADF_00547	3.1e-101	-	-	-	-	-	-	-	-
MKNPMADF_00548	3.86e-194	-	-	-	-	-	-	-	-
MKNPMADF_00549	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
MKNPMADF_00550	8.92e-29	-	-	-	-	-	-	-	-
MKNPMADF_00551	1.93e-284	bbsF_2	2.8.3.16	-	C	ko:K07749	-	ko00000,ko01000	acyl-CoA transferases carnitine dehydratase
MKNPMADF_00552	6.35e-146	-	-	-	K	-	-	-	FCD domain
MKNPMADF_00553	1.31e-202	-	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
MKNPMADF_00554	2.6e-131	ybbH	-	-	K	-	-	-	RpiR family transcriptional regulator
MKNPMADF_00555	9.69e-228	-	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MKNPMADF_00556	7.1e-162	garR	1.1.1.60	-	I	ko:K00042	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MKNPMADF_00557	4.97e-236	-	-	-	S	-	-	-	Putative nucleotide-binding of sugar-metabolising enzyme
MKNPMADF_00558	1.78e-284	hmrA	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
MKNPMADF_00559	6.67e-202	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MKNPMADF_00560	3.91e-145	-	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MKNPMADF_00561	4.2e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNPMADF_00562	3.72e-214	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MKNPMADF_00564	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MKNPMADF_00565	0.0	aguA	3.2.1.139	-	G	ko:K01235	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 67 family
MKNPMADF_00566	3.12e-223	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00567	2.69e-197	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKNPMADF_00568	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00569	8.36e-145	-	-	-	S	-	-	-	Protein of unknown function, DUF624
MKNPMADF_00570	1.94e-248	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MKNPMADF_00571	4.3e-43	-	-	-	D	-	-	-	nuclear chromosome segregation
MKNPMADF_00573	3.27e-276	hutI	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
MKNPMADF_00574	8.29e-252	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
MKNPMADF_00575	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_00576	9.9e-216	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_00577	4.75e-192	-	-	-	EP	ko:K02034,ko:K13891	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_00578	3.73e-240	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_00579	3.03e-242	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_00580	7.64e-222	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
MKNPMADF_00581	3.91e-307	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
MKNPMADF_00582	4.63e-175	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00583	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MKNPMADF_00584	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
MKNPMADF_00585	8.59e-249	mro	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Converts alpha-aldose to the beta-anomer
MKNPMADF_00586	3.52e-274	xylR5	-	-	GK	-	-	-	ROK family
MKNPMADF_00587	9.48e-157	-	-	-	S	ko:K09992	-	ko00000	Trehalose utilisation
MKNPMADF_00588	1.46e-282	yrbE	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_00589	0.0	-	-	-	KT	ko:K09684	-	ko00000,ko03000	PucR C-terminal helix-turn-helix domain
MKNPMADF_00590	6e-139	-	-	-	E	-	-	-	Asp/Glu/Hydantoin racemase
MKNPMADF_00591	0.0	-	-	-	S	-	-	-	OPT oligopeptide transporter protein
MKNPMADF_00592	1.65e-244	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
MKNPMADF_00593	2.24e-212	-	-	-	S	-	-	-	Protein of unknown function (DUF1177)
MKNPMADF_00594	9.34e-144	-	-	-	E	ko:K14591	-	ko00000	AroM protein
MKNPMADF_00595	2.45e-218	-	-	-	E	-	-	-	Thermophilic metalloprotease (M29)
MKNPMADF_00596	2.77e-238	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MKNPMADF_00597	2.4e-42	-	5.3.2.6	-	S	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Tautomerase enzyme
MKNPMADF_00598	1.91e-262	chrA	-	-	P	ko:K07240	-	ko00000,ko02000	chromate transporter, chromate ion transporter
MKNPMADF_00599	4.02e-58	M1-594	-	-	S	-	-	-	Thiamine-binding protein
MKNPMADF_00600	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKNPMADF_00601	4.66e-312	-	-	-	-	-	-	-	-
MKNPMADF_00603	5.75e-289	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
MKNPMADF_00604	8.25e-182	-	2.7.1.196, 2.7.1.205	-	K	ko:K02760,ko:K20480	ko00500,ko02024,ko02060,map00500,map02024,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	sequence-specific DNA binding
MKNPMADF_00605	2.61e-155	yflK	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_00606	2.71e-99	-	-	-	-	-	-	-	-
MKNPMADF_00607	1.5e-09	-	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
MKNPMADF_00608	1.52e-108	ssuE	1.5.1.38, 1.5.1.45	-	S	ko:K00299,ko:K16902	ko00380,ko00740,ko00920,ko01100,map00380,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
MKNPMADF_00609	6.13e-213	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_00610	6.22e-266	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MKNPMADF_00611	3.1e-170	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKNPMADF_00612	1.16e-161	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MKNPMADF_00613	7.34e-117	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKNPMADF_00614	3.56e-199	-	-	-	S	-	-	-	Carbohydrate esterase, sialic acid-specific acetylesterase
MKNPMADF_00615	2.06e-177	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
MKNPMADF_00616	9.71e-276	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
MKNPMADF_00617	1.89e-234	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
MKNPMADF_00618	2.08e-144	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
MKNPMADF_00619	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MKNPMADF_00620	1.23e-178	cbiX	4.99.1.3	-	C	ko:K03795	ko00860,ko01100,ko01120,map00860,map01100,map01120	ko00000,ko00001,ko01000	CbiX
MKNPMADF_00621	1.58e-127	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
MKNPMADF_00622	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MKNPMADF_00623	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MKNPMADF_00624	3.05e-22	-	-	-	-	-	-	-	-
MKNPMADF_00625	4.46e-196	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_00626	2.84e-77	-	-	-	K	-	-	-	GntR family transcriptional regulator
MKNPMADF_00627	1.53e-267	yraM	-	-	S	-	-	-	PrpF protein
MKNPMADF_00628	5.33e-88	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
MKNPMADF_00629	0.0	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctA family
MKNPMADF_00630	2.52e-263	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MKNPMADF_00631	1.53e-212	yraN	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_00632	1.25e-243	icd	1.1.1.41, 1.1.1.42, 1.1.1.85	-	CE	ko:K00030,ko:K00031,ko:K00052	ko00020,ko00290,ko00480,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00290,map00480,map00660,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
MKNPMADF_00633	0.0	-	-	-	C	ko:K13796	-	ko00000	COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit
MKNPMADF_00634	1.91e-236	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
MKNPMADF_00635	9.57e-269	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
MKNPMADF_00636	1.14e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNPMADF_00637	3.61e-132	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MKNPMADF_00638	1.38e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_00639	1.16e-220	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MKNPMADF_00640	4.45e-207	-	-	-	P	-	-	-	Arsenic resistance protein
MKNPMADF_00641	2.55e-117	-	-	-	-	-	-	-	-
MKNPMADF_00642	1.59e-154	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MKNPMADF_00643	9.97e-59	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00644	1.33e-64	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00645	2.66e-306	ywbA	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNPMADF_00646	4.1e-308	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKNPMADF_00647	2.13e-171	celCD	2.7.1.196, 2.7.1.205, 3.5.1.105	-	G	ko:K02759,ko:K03478	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
MKNPMADF_00648	2.91e-177	ybgA	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MKNPMADF_00649	0.0	chiA	3.2.1.14	GH18	G	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Glycoside Hydrolase Family 18
MKNPMADF_00651	6.3e-66	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
MKNPMADF_00652	7.81e-282	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_00653	8.43e-262	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MKNPMADF_00654	2.25e-302	kynU	3.7.1.3	-	E	ko:K01556	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively
MKNPMADF_00655	4.84e-144	kynB	3.5.1.9	-	S	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MKNPMADF_00656	3.68e-198	kynA	1.13.11.11	-	E	ko:K00453	ko00380,ko01100,map00380,map01100	ko00000,ko00001,ko00002,ko01000	Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
MKNPMADF_00657	8.29e-255	-	-	-	E	ko:K06296	-	ko00000,ko02000	Spore germination protein
MKNPMADF_00659	6.22e-267	gerAC1	-	-	S	ko:K06297	-	ko00000	spore germination
MKNPMADF_00660	0.0	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MKNPMADF_00661	2.77e-171	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MKNPMADF_00662	3.7e-297	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
MKNPMADF_00663	3.07e-240	pdxA	1.1.1.408, 1.1.1.409	-	H	ko:K22024	-	ko00000,ko01000	Belongs to the PdxA family
MKNPMADF_00664	1.72e-279	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
MKNPMADF_00665	1.91e-195	araQ5	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_00666	1.2e-208	cebF	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_00667	2.01e-291	lacE3	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
MKNPMADF_00670	1.08e-315	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
MKNPMADF_00671	1.02e-159	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKNPMADF_00672	8.17e-244	-	-	-	G	-	-	-	Acyltransferase family
MKNPMADF_00673	5.45e-205	-	-	-	P	-	-	-	YhfZ C-terminal domain
MKNPMADF_00674	2.33e-74	-	-	-	S	-	-	-	PRD domain
MKNPMADF_00675	4e-76	-	-	-	S	-	-	-	Protein of unknown function DUF2620
MKNPMADF_00676	9.85e-283	-	-	-	S	-	-	-	Protein of unknown function
MKNPMADF_00677	3.37e-220	php	-	-	S	ko:K07048	-	ko00000	Phosphotriesterase family
MKNPMADF_00678	6.17e-261	-	-	-	E	-	-	-	Cys/Met metabolism PLP-dependent enzyme
MKNPMADF_00679	4.12e-275	-	-	-	E	-	-	-	Alanine racemase, N-terminal domain
MKNPMADF_00680	6.5e-289	-	-	-	G	-	-	-	Metalloenzyme superfamily
MKNPMADF_00682	3.11e-155	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
MKNPMADF_00683	2.81e-244	-	-	-	O	-	-	-	DnaJ molecular chaperone homology domain
MKNPMADF_00684	1.86e-29	hscC	-	-	O	ko:K04045	-	ko00000,ko03110	Hsp70 protein
MKNPMADF_00685	2.43e-299	hscC	-	-	O	ko:K04045	-	ko00000,ko03110	Hsp70 protein
MKNPMADF_00686	1.61e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKNPMADF_00687	7.14e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MKNPMADF_00688	1.74e-222	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00689	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00690	3.52e-195	M1-465	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00691	1.29e-202	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00692	3.62e-65	esxA	-	-	S	-	-	-	Belongs to the WXG100 family
MKNPMADF_00693	3.1e-51	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
MKNPMADF_00694	4.04e-273	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
MKNPMADF_00695	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MKNPMADF_00696	0.0	yueB	-	-	S	-	-	-	domain protein
MKNPMADF_00697	2.06e-92	-	-	-	S	-	-	-	Family of unknown function (DUF5383)
MKNPMADF_00698	1.04e-60	-	-	-	-	-	-	-	-
MKNPMADF_00699	2.44e-65	-	-	-	-	-	-	-	-
MKNPMADF_00700	7.94e-97	-	-	-	-	-	-	-	-
MKNPMADF_00701	8.19e-311	-	-	-	S	-	-	-	nuclease activity
MKNPMADF_00703	3.39e-67	-	-	-	-	-	-	-	-
MKNPMADF_00706	2.46e-218	-	-	-	G	-	-	-	Glycoside hydrolase family 16
MKNPMADF_00710	7.99e-165	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	COG1136 ABC-type antimicrobial peptide transport system, ATPase component
MKNPMADF_00711	0.0	-	-	-	Q	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKNPMADF_00712	8.17e-114	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKNPMADF_00713	1.27e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MKNPMADF_00714	7.94e-150	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKNPMADF_00715	0.0	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_00716	9.03e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MKNPMADF_00717	2.11e-27	scdA	-	-	D	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MKNPMADF_00718	2.43e-52	scdA	-	-	D	ko:K07322	-	ko00000	Di-iron-containing protein involved in the repair of iron-sulfur clusters
MKNPMADF_00719	0.0	narG	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKNPMADF_00720	0.0	narH	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase, beta
MKNPMADF_00721	1.08e-147	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
MKNPMADF_00722	6.36e-161	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	nitrate reductase, gamma subunit
MKNPMADF_00723	5.89e-108	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	phosphoenolpyruvate-protein phosphotransferase activity
MKNPMADF_00724	2.88e-250	nreB	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MKNPMADF_00725	3.81e-142	nreC	-	-	T	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKNPMADF_00726	0.0	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKNPMADF_00727	0.0	narK	-	-	P	ko:K02575,ko:K10850	ko00910,ko02020,map00910,map02020	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MKNPMADF_00728	2.43e-157	-	-	-	S	-	-	-	YwiC-like protein
MKNPMADF_00729	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_00730	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_00731	1.3e-284	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	cheY-homologous receiver domain
MKNPMADF_00732	1.42e-220	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00733	7.21e-204	ytcP1	-	-	U	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00734	2.59e-51	-	-	-	-	-	-	-	-
MKNPMADF_00735	8.18e-128	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
MKNPMADF_00736	3.35e-140	apl	3.1.3.1	-	S	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	SNARE associated Golgi protein
MKNPMADF_00737	9.6e-317	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
MKNPMADF_00738	1.66e-214	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_00739	8.57e-248	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
MKNPMADF_00740	5.9e-259	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_00741	1.21e-137	desR	-	-	T	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKNPMADF_00742	3.13e-282	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
MKNPMADF_00743	8.78e-99	-	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
MKNPMADF_00744	1.85e-71	-	-	-	-	-	-	-	-
MKNPMADF_00745	6.99e-115	-	3.1.1.29	-	K	ko:K01056	-	ko00000,ko01000,ko03012	-acetyltransferase
MKNPMADF_00746	2.54e-306	-	-	-	EK	-	-	-	Alanine-glyoxylate amino-transferase
MKNPMADF_00747	5.3e-104	yvbK	-	-	K	-	-	-	acetyltransferase
MKNPMADF_00748	3.43e-187	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKNPMADF_00749	1.21e-104	-	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKNPMADF_00750	6.49e-252	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MKNPMADF_00751	4.61e-235	-	-	-	KT	ko:K02647	-	ko00000,ko03000	Sugar diacid utilization regulator
MKNPMADF_00752	1.13e-250	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
MKNPMADF_00753	3.95e-160	-	-	-	-	-	-	-	-
MKNPMADF_00754	4.33e-146	ppiB	5.2.1.8	-	O	ko:K01802,ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKNPMADF_00755	2.23e-235	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MKNPMADF_00756	4.18e-196	hisJ3	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	PHP domain
MKNPMADF_00757	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKNPMADF_00758	3.7e-123	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
MKNPMADF_00759	1.76e-165	-	-	-	-	ko:K06336	-	ko00000,ko01002	-
MKNPMADF_00760	1.19e-121	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
MKNPMADF_00761	4.52e-168	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MKNPMADF_00762	4.06e-223	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MKNPMADF_00763	6.51e-179	-	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MKNPMADF_00764	2.87e-216	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
MKNPMADF_00765	2.55e-285	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKNPMADF_00767	1.32e-252	aprE	3.4.21.62	-	O	ko:K01342	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKNPMADF_00768	1.29e-297	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix XRE-family like proteins
MKNPMADF_00769	3.58e-135	cwlK	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	Peptidase M15B and M15C DD-carboxypeptidase VanY endolysin
MKNPMADF_00770	7.54e-315	-	-	-	E	ko:K03294,ko:K14052	-	ko00000,ko02000	Amino acid permease
MKNPMADF_00771	9.9e-202	sseA	2.8.1.1, 2.8.1.2	-	P	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	ko00000,ko00001,ko01000	sulfurtransferase
MKNPMADF_00772	3.08e-283	yukF	-	-	QT	-	-	-	Transcriptional regulator
MKNPMADF_00773	1.31e-249	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
MKNPMADF_00774	2.2e-253	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
MKNPMADF_00775	5.77e-194	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
MKNPMADF_00776	8.67e-170	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKNPMADF_00777	3.82e-189	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
MKNPMADF_00778	4.65e-141	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_00779	2.46e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_00780	1.98e-199	-	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
MKNPMADF_00781	1.13e-288	-	2.7.13.3	-	T	ko:K07706,ko:K07717	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase-like ATPases
MKNPMADF_00782	5.9e-193	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
MKNPMADF_00783	6.65e-207	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_00784	2.02e-220	dppC	-	-	EP	ko:K16201	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_00785	2.13e-231	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_00786	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_00787	3.24e-221	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MKNPMADF_00788	3.2e-211	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MKNPMADF_00789	1.89e-230	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_00790	9.78e-78	hxlR	-	-	K	-	-	-	transcriptional
MKNPMADF_00791	9.96e-141	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MKNPMADF_00792	1.77e-167	-	-	-	T	-	-	-	Universal stress protein family
MKNPMADF_00793	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKNPMADF_00794	5.43e-85	mnhB2	-	-	P	ko:K05566	-	ko00000,ko02000	antiporter activity
MKNPMADF_00795	1.85e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_00796	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_00797	8.09e-111	mnhE2	-	-	P	ko:K05569	-	ko00000,ko02000	Na+/H+ ion antiporter subunit
MKNPMADF_00798	2.23e-51	mnhF2	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_00799	2.2e-77	-	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
MKNPMADF_00800	4.34e-200	-	-	-	S	-	-	-	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
MKNPMADF_00801	1.21e-246	-	-	-	G	-	-	-	Xylose isomerase
MKNPMADF_00802	1.72e-244	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_00803	5.44e-176	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_00804	5.18e-272	-	-	-	S	ko:K09927	-	ko00000	Winged helix DNA-binding domain
MKNPMADF_00805	8e-137	-	-	-	S	-	-	-	Integral membrane protein
MKNPMADF_00806	1.01e-62	-	-	-	-	-	-	-	-
MKNPMADF_00807	8.35e-177	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
MKNPMADF_00808	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKNPMADF_00809	3.34e-131	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNPMADF_00810	6.53e-171	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
MKNPMADF_00811	9.81e-77	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKNPMADF_00812	1.7e-237	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
MKNPMADF_00813	2.34e-284	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKNPMADF_00814	4.38e-35	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MKNPMADF_00815	8.86e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MKNPMADF_00816	2.01e-179	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
MKNPMADF_00817	3.15e-69	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
MKNPMADF_00818	5.84e-95	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MKNPMADF_00819	5.68e-235	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
MKNPMADF_00820	1.39e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
MKNPMADF_00821	6.56e-107	rsbW	2.7.11.1	-	T	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MKNPMADF_00822	1.49e-180	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKNPMADF_00823	9.86e-146	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
MKNPMADF_00824	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
MKNPMADF_00825	3.43e-13	-	-	-	-	-	-	-	-
MKNPMADF_00826	1.4e-114	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MKNPMADF_00834	3.12e-123	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
MKNPMADF_00835	3.55e-59	-	-	-	KQ	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_00836	1.72e-125	yrkC	-	-	G	-	-	-	Cupin domain
MKNPMADF_00837	5.94e-123	-	-	-	S	-	-	-	TraX protein
MKNPMADF_00838	3.56e-231	-	-	-	L	-	-	-	Transposase
MKNPMADF_00839	6.41e-126	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
MKNPMADF_00840	5.49e-48	-	-	-	L	ko:K07483	-	ko00000	Transposase
MKNPMADF_00841	1.99e-85	-	-	-	L	-	-	-	Transposase
MKNPMADF_00842	2.28e-172	-	-	-	L	-	-	-	IstB-like ATP binding protein
MKNPMADF_00843	4.37e-213	mviM3	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_00844	3.48e-40	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
MKNPMADF_00845	1.91e-98	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MKNPMADF_00846	2.26e-65	arsR	-	-	K	ko:K03892	-	ko00000,ko03000	ArsR family transcriptional regulator
MKNPMADF_00847	5.33e-86	cadI	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNPMADF_00848	9.94e-71	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
MKNPMADF_00849	3.96e-278	ydfA	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MKNPMADF_00850	9.45e-99	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MKNPMADF_00852	1.31e-294	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
MKNPMADF_00853	6.33e-207	catE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
MKNPMADF_00855	3.63e-143	ydhC	-	-	K	-	-	-	FCD
MKNPMADF_00856	4.62e-252	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
MKNPMADF_00857	2.8e-85	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNPMADF_00858	2.75e-154	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
MKNPMADF_00859	0.0	-	-	-	L	-	-	-	ABC transporter
MKNPMADF_00860	1.54e-96	-	-	-	K	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MKNPMADF_00861	1.05e-74	-	-	-	K	ko:K03892	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
MKNPMADF_00862	4.23e-87	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
MKNPMADF_00863	8.09e-65	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
MKNPMADF_00864	1.95e-160	azlC	-	-	E	-	-	-	AzlC protein
MKNPMADF_00865	3.12e-95	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_00866	5.39e-92	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
MKNPMADF_00867	1.11e-59	-	-	-	GM	-	-	-	NmrA-like family
MKNPMADF_00868	3.51e-290	-	-	-	F	-	-	-	Belongs to the Nudix hydrolase family
MKNPMADF_00869	7.09e-88	-	-	-	J	-	-	-	L-PSP family endoribonuclease
MKNPMADF_00870	3.99e-197	-	-	-	S	-	-	-	Phenazine biosynthesis-like protein
MKNPMADF_00871	2.83e-249	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
MKNPMADF_00872	0.0	-	-	-	K	ko:K03491	-	ko00000,ko03000	transcriptional regulator, MtlR
MKNPMADF_00873	7.2e-202	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MKNPMADF_00874	0.0	-	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKNPMADF_00875	1.85e-206	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MKNPMADF_00876	2.58e-126	-	-	-	-	-	-	-	-
MKNPMADF_00878	2.43e-34	-	-	-	-	-	-	-	-
MKNPMADF_00883	2.03e-08	-	-	-	-	-	-	-	-
MKNPMADF_00887	4.24e-89	puuR	-	-	K	-	-	-	sequence-specific DNA binding
MKNPMADF_00888	3.87e-87	puuR	-	-	K	-	-	-	sequence-specific DNA binding
MKNPMADF_00889	1.01e-233	-	-	-	V	-	-	-	Domain of unknown function (DUF3471)
MKNPMADF_00890	8.89e-156	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
MKNPMADF_00891	2.59e-77	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKNPMADF_00892	7.27e-73	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKNPMADF_00893	8.25e-271	-	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKNPMADF_00896	5.19e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MKNPMADF_00897	2.14e-105	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
MKNPMADF_00898	7.66e-163	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
MKNPMADF_00899	3.01e-112	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKNPMADF_00900	2.91e-231	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKNPMADF_00901	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
MKNPMADF_00902	3.56e-145	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKNPMADF_00903	7.3e-34	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MKNPMADF_00904	1.16e-178	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MKNPMADF_00905	5.64e-232	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNPMADF_00906	3.22e-142	metP_2	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MKNPMADF_00907	1.09e-185	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1464 ABC-type metal ion transport system, periplasmic component surface antigen
MKNPMADF_00908	3.97e-255	gldA	-	-	C	ko:K08317	-	ko00000,ko01000	COG0371 Glycerol dehydrogenase and related enzymes
MKNPMADF_00909	7.8e-152	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MKNPMADF_00910	7.46e-59	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKNPMADF_00911	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKNPMADF_00912	0.0	-	-	-	G	-	-	-	Mga helix-turn-helix domain
MKNPMADF_00913	1.37e-94	-	2.7.1.194	-	GT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNPMADF_00914	5.5e-56	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
MKNPMADF_00915	1.25e-282	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
MKNPMADF_00916	4.77e-165	-	-	-	S	-	-	-	carbohydrate derivative metabolic process
MKNPMADF_00917	3.39e-156	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MKNPMADF_00918	2.12e-183	-	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKNPMADF_00919	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
MKNPMADF_00920	7.31e-114	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MKNPMADF_00921	1.66e-126	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MKNPMADF_00922	3.23e-108	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MKNPMADF_00923	1.34e-233	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MKNPMADF_00924	6.4e-298	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
MKNPMADF_00925	4.72e-115	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
MKNPMADF_00926	2.79e-97	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
MKNPMADF_00927	5.19e-43	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MKNPMADF_00928	1.15e-178	nirC	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
MKNPMADF_00929	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
MKNPMADF_00930	3.27e-135	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
MKNPMADF_00931	2.66e-172	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MKNPMADF_00932	5.95e-112	-	-	-	S	-	-	-	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
MKNPMADF_00933	1.75e-10	-	-	-	-	-	-	-	-
MKNPMADF_00934	2.57e-10	-	-	-	-	-	-	-	-
MKNPMADF_00935	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MKNPMADF_00936	2.07e-90	-	-	-	S	-	-	-	GtrA-like protein
MKNPMADF_00937	2.22e-231	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
MKNPMADF_00938	2.38e-191	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
MKNPMADF_00939	2.04e-171	-	-	-	-	-	-	-	-
MKNPMADF_00940	1.33e-191	tcyA_1	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MKNPMADF_00941	7.32e-144	-	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00942	1.09e-151	-	-	-	E	ko:K02029,ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_00943	6.89e-192	-	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKNPMADF_00944	2.91e-94	-	-	-	M	-	-	-	ArpU family transcriptional regulator
MKNPMADF_00945	0.0	malK	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKNPMADF_00946	8.29e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MKNPMADF_00947	1.28e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
MKNPMADF_00948	6.51e-269	-	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MKNPMADF_00949	3.5e-69	-	-	-	S	-	-	-	Short C-terminal domain
MKNPMADF_00950	3.67e-93	-	-	-	-	-	-	-	-
MKNPMADF_00951	6.77e-100	-	-	-	-	-	-	-	-
MKNPMADF_00952	2.53e-184	-	-	-	D	-	-	-	Phage tail tape measure protein, TP901 family
MKNPMADF_00953	3.03e-169	-	-	-	S	-	-	-	Phage tail protein
MKNPMADF_00954	0.0	-	-	-	L	-	-	-	Phage minor structural protein
MKNPMADF_00956	7.02e-81	-	-	-	S	-	-	-	Bacteriophage holin family
MKNPMADF_00957	1.73e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
MKNPMADF_00958	9.24e-138	yfhC	-	-	C	-	-	-	nitroreductase
MKNPMADF_00959	4.62e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MKNPMADF_00960	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
MKNPMADF_00961	2.85e-13	-	-	-	-	-	-	-	-
MKNPMADF_00962	2.42e-26	-	-	-	L	-	-	-	Transposase IS200 like
MKNPMADF_00964	2.13e-227	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
MKNPMADF_00965	7.64e-94	-	-	-	CO	-	-	-	Thioredoxin
MKNPMADF_00966	2.1e-218	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
MKNPMADF_00967	2.38e-256	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MKNPMADF_00968	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
MKNPMADF_00969	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MKNPMADF_00970	3.89e-284	-	-	-	L	-	-	-	Arm DNA-binding domain
MKNPMADF_00971	1.14e-36	-	-	-	S	-	-	-	Domain of unknown function (DUF3173)
MKNPMADF_00972	6.28e-36	-	-	-	S	-	-	-	Helix-turn-helix domain
MKNPMADF_00973	1.09e-229	-	-	-	T	-	-	-	Histidine kinase-like ATPases
MKNPMADF_00974	1.4e-160	rrp1	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_00975	4.93e-175	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_00976	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MKNPMADF_00977	1.2e-259	-	-	-	L	ko:K07487	-	ko00000	Transposase domain (DUF772)
MKNPMADF_00978	0.0	-	-	-	L	-	-	-	Transposase
MKNPMADF_00979	1.95e-173	-	-	-	L	-	-	-	IstB-like ATP binding protein
MKNPMADF_00980	1.67e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_00981	5.45e-112	yqeB	-	-	-	-	-	-	-
MKNPMADF_00982	2.22e-83	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MKNPMADF_00983	1.68e-184	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MKNPMADF_00984	2.95e-124	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKNPMADF_00985	2.67e-52	-	-	-	S	-	-	-	Helix-turn-helix domain
MKNPMADF_00986	2.2e-42	-	-	-	K	-	-	-	Sigma-70, region 4
MKNPMADF_00987	8.22e-41	-	-	-	K	-	-	-	Sigma-70, region 4
MKNPMADF_00988	1.55e-206	-	-	-	I	-	-	-	Acyltransferase family
MKNPMADF_00989	2.13e-44	-	-	-	-	-	-	-	-
MKNPMADF_00990	1.46e-150	-	-	-	S	-	-	-	Sap, sulfolipid-1-addressing protein
MKNPMADF_00991	2.24e-134	-	-	-	K	-	-	-	BetI-type transcriptional repressor, C-terminal
MKNPMADF_00992	1.58e-94	-	-	-	L	ko:K07487	-	ko00000	Transposase
MKNPMADF_00993	2.46e-139	-	-	-	L	ko:K07487	-	ko00000	PFAM transposase IS4 family protein
MKNPMADF_00995	3.4e-176	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKNPMADF_00996	3.36e-31	-	-	-	K	-	-	-	transcriptional regulator
MKNPMADF_00997	2.38e-205	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
MKNPMADF_00998	3.11e-232	yddH	-	-	M	-	-	-	Lysozyme-like
MKNPMADF_00999	0.0	-	-	-	S	-	-	-	the current gene model (or a revised gene model) may contain a frame shift
MKNPMADF_01000	0.0	-	-	-	S	-	-	-	AAA-like domain
MKNPMADF_01001	2.89e-100	-	-	-	S	-	-	-	glyoxalase bleomycin resistance protein dioxygenase
MKNPMADF_01002	4.91e-278	-	-	-	C	-	-	-	Na+/H+ antiporter family
MKNPMADF_01003	2e-239	dapB	1.4.1.12, 1.4.1.26	-	S	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	ko00000,ko00001,ko01000	Dihydrodipicolinate reductase, N-terminus
MKNPMADF_01004	6.48e-216	-	-	-	K	-	-	-	LysR substrate binding domain
MKNPMADF_01005	2.11e-82	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
MKNPMADF_01006	7.26e-166	-	-	-	K	ko:K03088	-	ko00000,ko03021	TIGRFAM RNA polymerase sigma factor, sigma-70 family
MKNPMADF_01007	3.59e-49	ydfG	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
MKNPMADF_01008	3.12e-46	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKNPMADF_01009	2.83e-249	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
MKNPMADF_01010	2.21e-26	yisL	-	-	S	-	-	-	UPF0344 protein
MKNPMADF_01011	9.27e-110	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01012	6.5e-142	XK27_07680	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKNPMADF_01013	1.04e-229	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
MKNPMADF_01014	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
MKNPMADF_01015	3.44e-107	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	PFAM restriction modification system DNA specificity domain
MKNPMADF_01016	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	Type I restriction enzyme R protein N terminus (HSDR_N)
MKNPMADF_01017	6.5e-201	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKNPMADF_01018	5.05e-41	yvmA	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKNPMADF_01019	4.49e-97	rmaD	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
MKNPMADF_01020	8.32e-107	M1-431	-	-	S	-	-	-	Protein of unknown function (DUF1706)
MKNPMADF_01021	3.23e-223	dhaK	2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863,ko:K05878	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dihydroxyacetone kinase DhaK, subunit
MKNPMADF_01022	3.72e-139	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
MKNPMADF_01023	8.02e-84	-	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
MKNPMADF_01024	1.2e-32	-	-	-	S	-	-	-	YfhD-like protein
MKNPMADF_01025	1.18e-275	-	-	-	G	-	-	-	Transmembrane secretion effector
MKNPMADF_01026	8.62e-223	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MKNPMADF_01027	1.51e-87	-	-	-	-	-	-	-	-
MKNPMADF_01028	1.4e-283	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MKNPMADF_01030	0.0	-	-	-	S	-	-	-	proteins of the AP superfamily
MKNPMADF_01031	8.69e-67	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKNPMADF_01032	1.28e-190	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MKNPMADF_01033	1.17e-215	-	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
MKNPMADF_01034	0.0	-	-	-	KT	-	-	-	Transcriptional regulator
MKNPMADF_01035	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
MKNPMADF_01037	0.0	-	3.1.3.5, 3.6.1.45	-	F	ko:K01081,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
MKNPMADF_01038	1.3e-36	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_01039	1.4e-98	ygaO	-	-	-	-	-	-	-
MKNPMADF_01040	5.84e-129	-	-	-	Q	-	-	-	Isochorismatase family
MKNPMADF_01041	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
MKNPMADF_01042	0.0	abgT_2	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
MKNPMADF_01043	1.03e-283	cypA	-	-	C	ko:K15468	-	ko00000,ko01008	Cytochrome P450
MKNPMADF_01044	2.91e-27	-	-	-	-	-	-	-	-
MKNPMADF_01045	0.0	-	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
MKNPMADF_01046	1.63e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKNPMADF_01047	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MKNPMADF_01048	5.65e-160	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MKNPMADF_01049	7.2e-173	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
MKNPMADF_01050	1.08e-285	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
MKNPMADF_01051	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKNPMADF_01052	6.28e-130	-	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
MKNPMADF_01053	4.01e-200	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Substrate binding domain of ABC-type glycine betaine transport system
MKNPMADF_01054	1.73e-204	-	-	-	Q	-	-	-	calcium- and calmodulin-responsive adenylate cyclase activity
MKNPMADF_01055	0.0	-	-	-	M	-	-	-	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MKNPMADF_01056	1.07e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MKNPMADF_01057	0.0	-	-	-	K	ko:K02538	-	ko00000,ko03000	transcriptional antiterminator
MKNPMADF_01058	0.0	lipA1	-	-	S	-	-	-	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKNPMADF_01059	2.36e-145	mqnB	3.2.2.26	-	F	ko:K11783	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MKNPMADF_01060	2.42e-198	mqnD	-	-	S	ko:K11785	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MKNPMADF_01061	1.31e-135	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MKNPMADF_01062	2.56e-111	-	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
MKNPMADF_01063	2.19e-168	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MKNPMADF_01064	1.17e-167	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_01065	1.85e-202	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MKNPMADF_01066	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
MKNPMADF_01067	5.3e-150	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_01068	3.1e-168	mta	-	-	K	-	-	-	transcriptional
MKNPMADF_01069	8.51e-267	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
MKNPMADF_01070	2.2e-123	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
MKNPMADF_01073	7.15e-295	-	-	-	G	-	-	-	Major facilitator Superfamily
MKNPMADF_01074	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_01075	0.0	yheH	-	-	V	ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_01077	9.14e-188	-	-	-	-	-	-	-	-
MKNPMADF_01078	5.72e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MKNPMADF_01079	1.15e-173	-	-	-	-	-	-	-	-
MKNPMADF_01080	2.01e-286	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
MKNPMADF_01081	3.54e-102	fliA	-	-	K	ko:K02405,ko:K03093	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	sigma factor activity
MKNPMADF_01084	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
MKNPMADF_01085	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKNPMADF_01086	3.15e-154	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MKNPMADF_01087	3.73e-239	-	-	-	S	ko:K07795	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter family receptor
MKNPMADF_01088	7.13e-89	-	-	-	S	ko:K07794	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctB family
MKNPMADF_01089	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
MKNPMADF_01090	1.84e-07	-	-	-	T	-	-	-	SpoVT / AbrB like domain
MKNPMADF_01091	2.1e-90	-	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MKNPMADF_01093	1.02e-42	yebG	-	-	S	-	-	-	NETI protein
MKNPMADF_01094	9.63e-88	-	-	-	S	-	-	-	Calcium/calmodulin dependent protein kinase II association domain
MKNPMADF_01095	1.5e-128	-	-	-	-	-	-	-	-
MKNPMADF_01096	1.11e-152	-	-	-	S	-	-	-	PFAM AIG2 family protein
MKNPMADF_01097	3.8e-124	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKNPMADF_01098	1.27e-164	-	-	-	S	-	-	-	CAAX protease self-immunity
MKNPMADF_01099	2.26e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKNPMADF_01100	7.25e-264	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKNPMADF_01101	5.02e-313	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKNPMADF_01102	6.29e-162	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MKNPMADF_01103	5.87e-51	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNPMADF_01104	3.7e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNPMADF_01105	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNPMADF_01106	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKNPMADF_01107	5.6e-250	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MKNPMADF_01108	1.21e-130	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKNPMADF_01109	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MKNPMADF_01110	1.19e-285	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MKNPMADF_01111	6.36e-257	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MKNPMADF_01112	1.57e-193	fhuD9	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MKNPMADF_01113	6.18e-115	ttr	-	-	K	-	-	-	GCN5 family acetyltransferase
MKNPMADF_01114	1.18e-253	-	-	-	T	-	-	-	Signal transduction histidine kinase
MKNPMADF_01115	3.54e-140	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
MKNPMADF_01116	1.66e-217	yfiL	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKNPMADF_01117	3.04e-279	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MKNPMADF_01118	1.51e-237	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MKNPMADF_01120	4.3e-46	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MKNPMADF_01121	2.95e-46	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKNPMADF_01122	0.0	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MKNPMADF_01123	1.03e-76	-	-	-	-	-	-	-	-
MKNPMADF_01124	1.42e-15	-	-	-	S	-	-	-	Domain of unknown function (DUF4926)
MKNPMADF_01125	6.18e-69	-	-	-	-	-	-	-	-
MKNPMADF_01126	2.15e-87	-	-	-	-	-	-	-	-
MKNPMADF_01128	2.59e-123	-	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MKNPMADF_01129	5.92e-280	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
MKNPMADF_01130	4.62e-188	gbuB	-	-	P	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MKNPMADF_01131	3.98e-205	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
MKNPMADF_01132	1.17e-249	cfr	2.1.1.224	-	J	ko:K15632	-	ko00000,ko01000,ko01504,ko03009	Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
MKNPMADF_01133	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
MKNPMADF_01134	1.55e-66	yerC	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_01135	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKNPMADF_01136	0.0	acyII	3.5.1.11	-	S	ko:K01434	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000,ko01002	Penicillin amidase
MKNPMADF_01137	1.16e-209	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MKNPMADF_01138	5.18e-34	mepA	-	-	V	-	-	-	MATE efflux family protein
MKNPMADF_01140	3.16e-223	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_01141	1.45e-216	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_01142	1.02e-194	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKNPMADF_01144	8.05e-166	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MKNPMADF_01145	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MKNPMADF_01146	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKNPMADF_01147	5.23e-277	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
MKNPMADF_01148	4.51e-261	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
MKNPMADF_01149	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_01150	7.19e-240	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKNPMADF_01151	3.53e-207	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKNPMADF_01153	3.64e-223	-	-	-	-	-	-	-	-
MKNPMADF_01154	9.69e-114	yizA	-	-	S	-	-	-	DinB family
MKNPMADF_01155	6.86e-60	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKNPMADF_01156	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKNPMADF_01157	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKNPMADF_01158	1.26e-213	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKNPMADF_01159	4.52e-101	ykuN	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MKNPMADF_01160	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKNPMADF_01161	1.94e-119	-	-	-	-	-	-	-	-
MKNPMADF_01162	4.65e-40	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_01163	2.22e-46	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_01164	2.99e-39	-	-	-	K	-	-	-	MerR family transcriptional regulator
MKNPMADF_01165	5.22e-312	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
MKNPMADF_01166	0.0	-	4.2.1.82	-	EG	ko:K22396	ko00040,map00040	ko00000,ko00001,ko01000	Dehydratase family
MKNPMADF_01167	3.53e-178	-	-	-	K	ko:K19333	-	ko00000,ko03000	helix_turn_helix isocitrate lyase regulation
MKNPMADF_01168	2.17e-208	-	4.2.1.141	-	S	ko:K14259	ko00040,map00040	ko00000,ko00001,ko01000	Fumarylacetoacetate (FAA) hydrolase family
MKNPMADF_01169	1.16e-211	-	4.1.2.28, 4.3.3.7	-	EM	ko:K01714,ko:K22397	ko00040,ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00040,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MKNPMADF_01170	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_01171	8.62e-166	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
MKNPMADF_01172	1.14e-162	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKNPMADF_01173	0.0	psaA3	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Zinc-uptake complex component A periplasmic
MKNPMADF_01174	4.44e-224	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MKNPMADF_01175	2.41e-215	yjiA	-	-	S	-	-	-	Cobalamin biosynthesis protein CobW
MKNPMADF_01176	2.83e-249	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
MKNPMADF_01177	1.43e-186	-	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MKNPMADF_01178	6.54e-95	dcd	3.5.4.13	-	F	ko:K01494	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	2'-deoxycytidine 5'-triphosphate deaminase (DCD)
MKNPMADF_01180	3.41e-192	-	-	-	S	-	-	-	Alpha beta hydrolase
MKNPMADF_01181	7.47e-172	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
MKNPMADF_01182	8.47e-207	-	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MKNPMADF_01183	4.59e-96	-	-	-	S	-	-	-	DinB superfamily
MKNPMADF_01184	0.0	M1-1044	-	-	S	-	-	-	Belongs to the UPF0061 (SELO) family
MKNPMADF_01185	3e-226	nagC_1	-	-	GK	-	-	-	ROK family
MKNPMADF_01186	3.53e-258	glcP1	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
MKNPMADF_01187	4.1e-206	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase (reverse transcriptase)
MKNPMADF_01188	0.0	yicI	3.2.1.177	GH31	G	ko:K01811	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 31 family
MKNPMADF_01189	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_01190	0.0	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKNPMADF_01191	3.93e-222	-	-	-	P	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01192	1.08e-215	lplC1	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01193	0.0	lplA3	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_01194	0.0	-	3.2.1.51	GH95	G	ko:K15923	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65, N-terminal domain
MKNPMADF_01195	8.92e-164	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
MKNPMADF_01196	2.41e-133	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_01197	1.6e-246	-	4.2.2.2	-	M	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectic acid lyase
MKNPMADF_01198	2.23e-202	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_01199	0.0	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_01200	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_01201	6.89e-231	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MKNPMADF_01202	3.76e-189	ytcP3	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01203	4.05e-214	-	-	-	E	-	-	-	Abhydrolase family
MKNPMADF_01204	0.0	-	3.2.1.37, 3.2.1.55	GH43,GH51	G	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
MKNPMADF_01205	1.39e-283	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MKNPMADF_01206	2.73e-101	-	-	-	G	-	-	-	carbohydrate transport
MKNPMADF_01207	2.02e-156	yteU	-	-	S	-	-	-	Integral membrane protein
MKNPMADF_01208	6.8e-316	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_01209	0.0	uxaA	4.2.1.7	-	G	ko:K01685	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
MKNPMADF_01210	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
MKNPMADF_01211	1.98e-218	-	-	-	K	-	-	-	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKNPMADF_01212	6.72e-97	srlR	-	-	K	-	-	-	Glucitol operon activator
MKNPMADF_01213	2.18e-126	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
MKNPMADF_01214	2.37e-223	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
MKNPMADF_01215	4.84e-73	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MKNPMADF_01216	5.87e-182	-	1.1.1.140	-	C	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_01217	6.72e-202	-	-	AA10,CBM73	D	ko:K03933	-	ko00000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
MKNPMADF_01218	1.75e-43	-	-	-	S	-	-	-	Sporulation inhibitor A
MKNPMADF_01219	2.57e-128	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MKNPMADF_01220	0.0	-	-	-	M	-	-	-	Domain of unknown function DUF11
MKNPMADF_01221	8.71e-208	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase (reverse transcriptase)
MKNPMADF_01222	6.32e-158	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_01223	4.5e-212	ycbM	-	-	T	-	-	-	Histidine kinase
MKNPMADF_01224	3.08e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_01225	8.38e-144	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKNPMADF_01226	6.76e-188	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_01227	1.62e-52	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01228	9.49e-143	ydfE	-	-	S	-	-	-	Flavin reductase like domain
MKNPMADF_01229	1.55e-152	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
MKNPMADF_01230	6.61e-190	-	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MKNPMADF_01231	1.38e-235	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_01232	5.03e-165	yrkP	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulator
MKNPMADF_01233	1.91e-238	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Arginase family
MKNPMADF_01234	2.23e-150	-	-	-	S	-	-	-	HTH domain
MKNPMADF_01235	1.45e-265	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MKNPMADF_01236	3.73e-216	eutB	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MKNPMADF_01237	2.97e-215	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MKNPMADF_01238	6.91e-06	-	-	-	S	-	-	-	Sporulation inhibitor A
MKNPMADF_01239	6.4e-149	yhcQ	-	-	M	-	-	-	Spore coat protein
MKNPMADF_01240	8.58e-64	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKNPMADF_01241	8.76e-217	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
MKNPMADF_01242	1.87e-105	ycgF	-	-	E	-	-	-	Lysine exporter protein LysE YggA
MKNPMADF_01243	1.27e-55	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
MKNPMADF_01244	4.97e-24	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MKNPMADF_01245	1.25e-47	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKNPMADF_01246	0.0	-	-	-	M	-	-	-	nuclease activity
MKNPMADF_01247	2.83e-69	-	-	-	-	-	-	-	-
MKNPMADF_01248	1.39e-83	-	-	-	-	-	-	-	-
MKNPMADF_01249	5.39e-88	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MKNPMADF_01250	5.58e-76	-	-	-	-	-	-	-	-
MKNPMADF_01251	1.56e-103	-	-	-	-	-	-	-	-
MKNPMADF_01252	1.28e-65	-	-	-	-	-	-	-	-
MKNPMADF_01253	3.82e-20	binR	-	-	L	-	-	-	COG1961 Site-specific recombinases, DNA invertase Pin homologs
MKNPMADF_01254	5.62e-146	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_01255	2.53e-265	-	-	-	S	-	-	-	Platelet-activating factor acetylhydrolase, isoform II
MKNPMADF_01256	1.02e-98	yuxK	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_01257	4.37e-124	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
MKNPMADF_01258	0.0	-	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKNPMADF_01259	4.59e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
MKNPMADF_01260	1.05e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
MKNPMADF_01261	3.84e-94	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKNPMADF_01262	0.0	spaK	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	His Kinase A (phosphoacceptor) domain
MKNPMADF_01263	2.14e-155	spaR	-	-	K	ko:K20488	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C terminal
MKNPMADF_01264	2.09e-167	spaG	-	-	S	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKNPMADF_01265	5.28e-160	spaE	-	-	S	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
MKNPMADF_01266	3.36e-154	spaF	-	-	V	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_01267	2.03e-217	yisR1	3.2.1.23	-	K	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	AraC-like ligand binding domain
MKNPMADF_01268	0.0	-	-	-	S	ko:K09955	-	ko00000	Beta-L-arabinofuranosidase, GH127
MKNPMADF_01269	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_01270	6.87e-216	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01271	5.51e-193	malG	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01272	9.8e-124	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKNPMADF_01273	5.31e-85	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_01274	2.51e-261	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
MKNPMADF_01275	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_01276	1.05e-80	-	-	-	K	-	-	-	LysR substrate binding domain
MKNPMADF_01277	6.33e-93	-	-	-	K	-	-	-	LysR substrate binding domain
MKNPMADF_01278	6.69e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKNPMADF_01279	2.07e-199	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
MKNPMADF_01280	0.0	dld	1.1.2.4, 1.1.3.15	-	C	ko:K00102,ko:K00104	ko00620,ko00630,ko01100,ko01110,ko01120,ko01130,map00620,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MKNPMADF_01281	0.0	-	-	-	T	-	-	-	COG0642 Signal transduction histidine kinase
MKNPMADF_01282	2.68e-105	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKNPMADF_01283	8.93e-249	sbp	-	-	P	ko:K02048	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG1613 ABC-type sulfate transport system, periplasmic component
MKNPMADF_01284	1.19e-172	cysT	-	-	O	ko:K02046	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0555 ABC-type sulfate transport system, permease component
MKNPMADF_01285	1.6e-175	cysW	-	-	P	ko:K02047	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG4208 ABC-type sulfate transport system, permease component
MKNPMADF_01286	2.58e-252	cysA	3.6.3.25	-	P	ko:K02045	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MKNPMADF_01287	5.3e-238	-	-	-	-	-	-	-	-
MKNPMADF_01288	1.6e-177	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	transport system, ATPase component
MKNPMADF_01289	5.7e-218	-	-	-	S	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKNPMADF_01290	3.35e-222	-	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	transport system, periplasmic component
MKNPMADF_01291	3.01e-292	-	-	-	S	ko:K07112	-	ko00000	Sulphur transport
MKNPMADF_01292	0.0	XK27_11280	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MKNPMADF_01293	2.22e-232	dppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_01294	6.16e-236	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_01295	0.0	hbpA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_01296	2.31e-232	dppB	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_01297	3.84e-204	dppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_01298	1.84e-199	pepI	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha/beta hydrolase family
MKNPMADF_01299	1.27e-81	gpm5	3.1.3.3, 5.4.2.11	-	G	ko:K01834,ko:K22305	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	alpha-ribazole phosphatase activity
MKNPMADF_01300	8.48e-132	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01301	7.83e-301	-	-	-	V	-	-	-	MatE
MKNPMADF_01302	4.56e-175	-	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKNPMADF_01303	2.12e-183	ptxC	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_01304	3.49e-175	phnE	-	-	P	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_01305	1.8e-179	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MKNPMADF_01306	2.01e-215	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
MKNPMADF_01307	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKNPMADF_01308	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKNPMADF_01309	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_01310	1.01e-292	kinB3	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_01311	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKNPMADF_01312	0.0	glpD	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MKNPMADF_01313	2.79e-120	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MKNPMADF_01314	1.87e-305	alsT	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MKNPMADF_01315	3.85e-298	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKNPMADF_01316	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
MKNPMADF_01317	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
MKNPMADF_01318	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_01319	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
MKNPMADF_01320	2.57e-160	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
MKNPMADF_01321	3.12e-110	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
MKNPMADF_01322	4.18e-261	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MKNPMADF_01323	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKNPMADF_01324	1.17e-169	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_01325	4.33e-207	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MKNPMADF_01326	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKNPMADF_01327	2.05e-231	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
MKNPMADF_01328	4.91e-302	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKNPMADF_01329	2.07e-75	-	-	-	-	-	-	-	-
MKNPMADF_01330	5.13e-61	-	-	-	K	-	-	-	SpoVT / AbrB like domain
MKNPMADF_01331	1.81e-54	-	-	-	-	-	-	-	-
MKNPMADF_01332	5.77e-145	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Caulimovirus viroplasmin
MKNPMADF_01333	2.49e-310	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MKNPMADF_01334	1.88e-309	-	1.14.13.59	-	Q	ko:K03897	ko00310,ko01120,map00310,map01120	ko00000,ko00001,ko01000	L-lysine 6-monooxygenase (NADPH-requiring)
MKNPMADF_01335	0.0	kat	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKNPMADF_01336	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
MKNPMADF_01337	8.05e-167	-	-	-	-	-	-	-	-
MKNPMADF_01338	6.68e-240	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MKNPMADF_01339	4.16e-314	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
MKNPMADF_01340	1.21e-29	-	-	-	S	-	-	-	Fur-regulated basic protein B
MKNPMADF_01343	1.97e-188	yfkD	-	-	S	-	-	-	YfkD-like protein
MKNPMADF_01344	3.26e-277	yfkA	-	-	S	-	-	-	YfkB-like domain
MKNPMADF_01345	1.02e-146	-	-	-	G	ko:K15640	-	ko00000	Belongs to the phosphoglycerate mutase family
MKNPMADF_01346	1.57e-314	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKNPMADF_01347	4.58e-181	-	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
MKNPMADF_01348	1.29e-189	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
MKNPMADF_01350	3.45e-209	-	-	-	O	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
MKNPMADF_01351	9.82e-92	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_01352	1.14e-107	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_01353	2.96e-146	surE	3.1.3.5	-	S	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Survival protein SurE
MKNPMADF_01354	3.78e-175	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_01355	5.67e-236	-	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01356	1.84e-172	-	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKNPMADF_01357	2.29e-81	-	-	-	-	-	-	-	-
MKNPMADF_01358	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKNPMADF_01359	1.41e-243	mccF	-	-	V	-	-	-	LD-carboxypeptidase
MKNPMADF_01360	1.36e-65	-	-	-	-	-	-	-	-
MKNPMADF_01361	6.23e-213	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
MKNPMADF_01362	1.03e-177	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
MKNPMADF_01363	8.82e-68	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
MKNPMADF_01364	9.25e-30	-	-	-	S	-	-	-	YpzG-like protein
MKNPMADF_01365	2.33e-237	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
MKNPMADF_01366	2.22e-256	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
MKNPMADF_01367	2.34e-162	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_01368	2.23e-77	-	-	-	-	-	-	-	-
MKNPMADF_01369	5.62e-27	yfhS	-	-	-	-	-	-	-
MKNPMADF_01370	9.29e-169	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_01371	1.43e-21	-	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
MKNPMADF_01372	2.94e-133	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
MKNPMADF_01373	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
MKNPMADF_01374	1.04e-234	ygaE	-	-	S	-	-	-	Membrane
MKNPMADF_01375	1.68e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MKNPMADF_01376	4.67e-114	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
MKNPMADF_01377	1.8e-220	ghrA	-	-	EH	-	-	-	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNPMADF_01378	6.47e-64	-	-	-	S	-	-	-	Cyclic-di-AMP receptor
MKNPMADF_01379	1.18e-103	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MKNPMADF_01380	6.28e-75	ygzB	-	-	S	-	-	-	UPF0295 protein
MKNPMADF_01397	0.0	yobO	-	-	M	-	-	-	Pectate lyase superfamily protein
MKNPMADF_01399	4.98e-10	-	-	-	S	-	-	-	Protein of unknown function (DUF3533)
MKNPMADF_01400	1.18e-61	-	-	-	K	-	-	-	ArsR family transcriptional regulator
MKNPMADF_01401	1.88e-249	ybcL	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MKNPMADF_01402	9.22e-45	-	-	-	M	-	-	-	Host cell surface-exposed lipoprotein
MKNPMADF_01403	1.3e-79	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01404	1.21e-135	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_01405	6.89e-42	-	-	-	E	-	-	-	lactoylglutathione lyase activity
MKNPMADF_01406	7.14e-111	-	-	-	F	-	-	-	uridine kinase
MKNPMADF_01407	1.3e-155	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_01408	1.51e-299	pbpE	-	-	V	-	-	-	Beta-lactamase
MKNPMADF_01409	4.79e-107	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
MKNPMADF_01410	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
MKNPMADF_01411	2.54e-208	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_01412	0.0	lacZ	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MKNPMADF_01413	0.0	-	-	-	G	-	-	-	alpha-L-rhamnosidase
MKNPMADF_01414	0.0	-	-	-	K	-	-	-	Mga helix-turn-helix domain
MKNPMADF_01415	6.12e-278	-	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	amidohydrolase
MKNPMADF_01416	1.88e-67	-	-	-	S	-	-	-	PRD domain
MKNPMADF_01417	2.68e-79	-	-	-	S	-	-	-	Glycine-rich SFCGS
MKNPMADF_01418	6.36e-78	-	-	-	S	-	-	-	Domain of unknown function (DUF4312)
MKNPMADF_01419	9.36e-179	-	-	-	S	-	-	-	Domain of unknown function (DUF4311)
MKNPMADF_01420	8.24e-146	-	-	-	S	-	-	-	Domain of unknown function (DUF4310)
MKNPMADF_01421	1.01e-251	selA	2.9.1.1	-	E	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
MKNPMADF_01422	2.12e-164	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
MKNPMADF_01423	2.19e-88	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MKNPMADF_01424	8.96e-228	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_01425	5.33e-236	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKNPMADF_01426	8.46e-65	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MKNPMADF_01427	5.03e-122	-	-	-	K	-	-	-	Winged helix DNA-binding domain
MKNPMADF_01428	8.12e-173	-	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MKNPMADF_01429	8.55e-135	-	-	-	K	-	-	-	TetR family transcriptional regulator
MKNPMADF_01430	2.47e-33	-	-	-	CH	-	-	-	FAD binding domain
MKNPMADF_01431	7.89e-142	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKNPMADF_01432	1.11e-173	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MKNPMADF_01433	2.08e-146	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_01434	2.88e-220	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
MKNPMADF_01435	4.23e-76	ydzF	-	-	K	-	-	-	HxlR-like helix-turn-helix
MKNPMADF_01436	3.41e-78	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_01437	7.2e-76	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01438	5.91e-297	serS3	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKNPMADF_01439	3.27e-167	-	-	-	L	-	-	-	DNA alkylation repair enzyme
MKNPMADF_01440	5.45e-146	-	-	-	S	-	-	-	AAA domain
MKNPMADF_01441	2.7e-118	-	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Phosphoglycerate mutase family
MKNPMADF_01442	4.16e-245	-	-	-	T	-	-	-	Signal transduction histidine kinase
MKNPMADF_01443	2.39e-138	-	-	-	KT	-	-	-	LuxR family transcriptional regulator
MKNPMADF_01444	6.26e-218	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKNPMADF_01445	1.16e-271	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKNPMADF_01446	6.9e-240	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKNPMADF_01447	1.26e-184	gspA	-	-	M	-	-	-	Glycosyl transferase family 8
MKNPMADF_01448	1.08e-83	yxjI	-	-	S	-	-	-	LURP-one-related
MKNPMADF_01449	1.93e-189	adcA	-	-	P	ko:K09815,ko:K09818	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MKNPMADF_01450	9.34e-162	-	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKNPMADF_01451	1.45e-120	p20	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKNPMADF_01452	3.13e-62	-	-	-	-	-	-	-	-
MKNPMADF_01453	7.8e-135	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKNPMADF_01454	0.0	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
MKNPMADF_01455	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K06931,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKNPMADF_01456	1.8e-69	-	-	-	S	-	-	-	Regulatory protein YrvL
MKNPMADF_01457	6.63e-234	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
MKNPMADF_01458	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKNPMADF_01459	5.85e-92	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	Reverse transcriptase (RNA-dependent DNA polymerase)
MKNPMADF_01460	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
MKNPMADF_01461	1.77e-112	-	-	-	-	-	-	-	-
MKNPMADF_01462	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_01463	1.56e-252	pamO	-	-	P	ko:K07222	-	ko00000	Flavin-binding monooxygenase-like
MKNPMADF_01464	0.0	scrA5	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_01465	0.0	bglC1	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MKNPMADF_01466	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKNPMADF_01467	4.85e-193	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
MKNPMADF_01468	1.79e-117	-	-	-	S	-	-	-	MepB protein
MKNPMADF_01469	1.52e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_01470	3.08e-164	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
MKNPMADF_01471	1.81e-80	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_01472	2.98e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKNPMADF_01473	7.25e-145	-	-	-	-	-	-	-	-
MKNPMADF_01474	4.42e-249	yhfE	-	-	G	-	-	-	peptidase M42
MKNPMADF_01475	5.28e-105	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MKNPMADF_01476	2.47e-125	yhzB	-	-	S	-	-	-	B3/4 domain
MKNPMADF_01477	4.83e-277	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MKNPMADF_01478	2.23e-119	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKNPMADF_01479	6.92e-101	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_01480	9.22e-213	yhbB	-	-	S	-	-	-	Putative amidase domain
MKNPMADF_01481	7.16e-114	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKNPMADF_01482	2.08e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
MKNPMADF_01483	2.27e-69	-	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MKNPMADF_01484	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
MKNPMADF_01485	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
MKNPMADF_01486	5.21e-111	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKNPMADF_01487	4.26e-131	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKNPMADF_01488	4.66e-177	cysA1	-	-	S	-	-	-	AAA domain
MKNPMADF_01489	4.51e-281	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
MKNPMADF_01492	9.24e-200	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01493	0.0	-	-	-	EGP	-	-	-	the major facilitator superfamily
MKNPMADF_01494	6.26e-222	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKNPMADF_01495	6.07e-189	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
MKNPMADF_01497	2.91e-104	-	-	-	S	-	-	-	Protein of unknown function (DUF664)
MKNPMADF_01498	0.0	-	-	-	G	ko:K10297	-	ko00000,ko04121	Right handed beta helix region
MKNPMADF_01499	3.19e-205	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_01500	0.0	-	-	-	E	ko:K03307	-	ko00000	Sodium:solute symporter family
MKNPMADF_01501	2.21e-164	-	-	-	K	ko:K03710	-	ko00000,ko03000	UTRA
MKNPMADF_01502	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MKNPMADF_01503	3.27e-169	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
MKNPMADF_01504	9.47e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKNPMADF_01505	6.82e-170	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKNPMADF_01506	1.96e-161	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
MKNPMADF_01507	1.3e-284	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MKNPMADF_01508	8.12e-151	-	-	-	Q	-	-	-	Fumarylacetoacetate (FAA) hydrolase family
MKNPMADF_01509	8.67e-171	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MKNPMADF_01511	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKNPMADF_01512	1.61e-156	sfsA	-	-	S	ko:K06206	-	ko00000	Sugar fermentation stimulation protein
MKNPMADF_01513	0.0	-	1.1.5.3	-	C	ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
MKNPMADF_01514	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
MKNPMADF_01515	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
MKNPMADF_01516	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_01517	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_01518	1.01e-292	avtA	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MKNPMADF_01519	5.61e-264	-	-	-	L	ko:K07487	-	ko00000	Transposase
MKNPMADF_01520	4.1e-193	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Peptidase family M48
MKNPMADF_01521	3.52e-124	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MKNPMADF_01522	1.97e-275	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MKNPMADF_01523	0.0	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
MKNPMADF_01524	3.93e-41	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
MKNPMADF_01525	1.3e-170	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
MKNPMADF_01526	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKNPMADF_01528	1.38e-274	-	-	-	-	-	-	-	-
MKNPMADF_01529	1.72e-101	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
MKNPMADF_01530	8.44e-262	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_01531	1.11e-204	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
MKNPMADF_01532	1.71e-30	-	-	-	-	-	-	-	-
MKNPMADF_01534	1.98e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
MKNPMADF_01535	2.8e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MKNPMADF_01536	6.54e-198	yhaX	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKNPMADF_01538	1.47e-66	-	-	-	-	-	-	-	-
MKNPMADF_01539	2.7e-159	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_01540	0.0	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_01541	4.85e-231	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
MKNPMADF_01542	1.14e-57	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
MKNPMADF_01543	2.97e-211	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKNPMADF_01544	2.48e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKNPMADF_01545	8.43e-141	-	-	-	S	-	-	-	Protein conserved in bacteria
MKNPMADF_01546	1.67e-140	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
MKNPMADF_01547	1.23e-66	yhaH	-	-	D	-	-	-	gas vesicle protein
MKNPMADF_01548	4.71e-263	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKNPMADF_01549	5.23e-97	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MKNPMADF_01550	8.06e-177	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
MKNPMADF_01551	1.35e-282	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_01552	4.46e-165	ecsC	-	-	S	-	-	-	EcsC protein family
MKNPMADF_01553	1.59e-156	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
MKNPMADF_01554	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKNPMADF_01555	5.06e-260	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MKNPMADF_01556	2.93e-233	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
MKNPMADF_01557	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MKNPMADF_01559	4.46e-132	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
MKNPMADF_01560	7.15e-295	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKNPMADF_01561	3.91e-95	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
MKNPMADF_01562	1.11e-206	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
MKNPMADF_01563	4.96e-118	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
MKNPMADF_01564	5.12e-266	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKNPMADF_01565	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
MKNPMADF_01566	4.42e-188	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
MKNPMADF_01567	5.5e-262	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MKNPMADF_01568	8.41e-234	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
MKNPMADF_01569	4.74e-25	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKNPMADF_01570	1.3e-82	-	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	cytochrome c oxidase subunit II
MKNPMADF_01571	1.83e-112	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
MKNPMADF_01572	6.43e-133	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKNPMADF_01573	6.39e-234	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKNPMADF_01574	1.03e-37	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
MKNPMADF_01575	1.7e-238	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKNPMADF_01576	4.38e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKNPMADF_01577	1.58e-50	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
MKNPMADF_01578	2.71e-76	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
MKNPMADF_01579	3.82e-94	-	-	-	S	-	-	-	membrane
MKNPMADF_01580	7.4e-41	yodI	-	-	-	-	-	-	-
MKNPMADF_01581	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKNPMADF_01582	9.5e-30	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
MKNPMADF_01583	6.1e-294	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKNPMADF_01584	3.84e-192	secF	-	-	U	ko:K03074,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MKNPMADF_01585	5.69e-50	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
MKNPMADF_01586	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MKNPMADF_01587	1.64e-119	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKNPMADF_01588	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKNPMADF_01589	1.26e-95	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKNPMADF_01590	2.37e-130	-	-	-	L	ko:K07482	-	ko00000	Integrase
MKNPMADF_01591	5.96e-240	-	-	-	K	-	-	-	LacI family transcriptional regulator
MKNPMADF_01592	5.08e-182	thuA	-	-	G	-	-	-	Trehalose utilisation
MKNPMADF_01593	8.24e-248	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_01594	1.35e-255	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
MKNPMADF_01596	3.22e-306	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MKNPMADF_01597	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MKNPMADF_01598	8.64e-273	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MKNPMADF_01599	5.89e-66	-	-	-	-	-	-	-	-
MKNPMADF_01600	1.67e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MKNPMADF_01601	2.48e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MKNPMADF_01602	7.73e-139	rsfA	-	-	S	ko:K06314	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_01603	2.58e-293	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MKNPMADF_01604	8.4e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_01605	1.04e-268	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKNPMADF_01606	1.05e-275	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKNPMADF_01607	5.69e-81	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKNPMADF_01608	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKNPMADF_01609	1.14e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_01610	1.11e-41	yrzR	-	-	-	-	-	-	-
MKNPMADF_01611	1.8e-232	yrrI	-	-	S	-	-	-	AI-2E family transporter
MKNPMADF_01612	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKNPMADF_01613	1.32e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MKNPMADF_01614	1.28e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKNPMADF_01615	2.04e-43	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MKNPMADF_01616	2.35e-266	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKNPMADF_01617	3.15e-146	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
MKNPMADF_01618	4.67e-147	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MKNPMADF_01619	2.58e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKNPMADF_01620	6.64e-17	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
MKNPMADF_01621	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
MKNPMADF_01622	2.91e-191	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MKNPMADF_01623	2.39e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKNPMADF_01625	1.03e-100	-	-	-	-	-	-	-	-
MKNPMADF_01626	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKNPMADF_01627	1.13e-187	-	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKNPMADF_01628	1.43e-181	-	-	-	P	ko:K02031	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
MKNPMADF_01629	3.7e-204	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MKNPMADF_01630	9.56e-194	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01631	9.47e-137	arpR	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_01632	0.0	-	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Starch/carbohydrate-binding module (family 53)
MKNPMADF_01633	5.94e-70	-	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKNPMADF_01634	4.16e-134	XK27_06885	-	-	L	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MKNPMADF_01635	9.51e-239	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MKNPMADF_01636	0.0	-	-	-	S	-	-	-	Membrane
MKNPMADF_01637	2.33e-283	hipO3	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
MKNPMADF_01638	1.42e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
MKNPMADF_01639	7.36e-159	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKNPMADF_01640	2.85e-222	-	-	-	P	-	-	-	Transporter associated domain
MKNPMADF_01641	2.24e-34	-	-	-	-	-	-	-	-
MKNPMADF_01644	1.91e-69	-	-	-	-	-	-	-	-
MKNPMADF_01645	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
MKNPMADF_01646	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKNPMADF_01647	2.15e-73	nirD	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
MKNPMADF_01648	0.0	nirB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MKNPMADF_01649	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MKNPMADF_01650	1.84e-281	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
MKNPMADF_01651	0.0	-	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MKNPMADF_01653	2.4e-191	thiD	2.5.1.3, 2.7.1.49, 2.7.4.7	-	H	ko:K00941,ko:K14153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKNPMADF_01654	5.78e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKNPMADF_01655	1.13e-81	-	-	-	P	ko:K05571	-	ko00000,ko02000	Na+/H+ antiporter subunit
MKNPMADF_01656	4.41e-52	-	-	-	P	ko:K05570	-	ko00000,ko02000	Multiple resistance and pH regulation protein F (MrpF / PhaF)
MKNPMADF_01657	8.91e-106	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_01658	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_01659	1.13e-66	mnhC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_01660	4.26e-93	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MKNPMADF_01661	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MKNPMADF_01663	1.52e-125	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
MKNPMADF_01664	1.68e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MKNPMADF_01665	3.71e-197	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKNPMADF_01666	2.17e-62	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
MKNPMADF_01667	4.08e-137	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKNPMADF_01668	8.22e-138	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
MKNPMADF_01669	7.46e-81	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKNPMADF_01670	8.76e-201	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
MKNPMADF_01671	1.62e-172	-	-	-	S	-	-	-	Methyltransferase domain
MKNPMADF_01672	3.39e-189	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKNPMADF_01673	3.02e-129	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
MKNPMADF_01674	9.98e-140	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MKNPMADF_01675	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MKNPMADF_01676	9.62e-09	-	-	-	S	-	-	-	YqzM-like protein
MKNPMADF_01677	6.51e-226	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MKNPMADF_01678	1.15e-48	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MKNPMADF_01679	2.82e-259	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MKNPMADF_01680	2.07e-262	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
MKNPMADF_01681	1.03e-68	-	-	-	-	-	-	-	-
MKNPMADF_01682	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKNPMADF_01683	7.46e-279	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
MKNPMADF_01684	1.7e-238	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKNPMADF_01685	2.88e-110	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKNPMADF_01686	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MKNPMADF_01687	3.2e-265	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKNPMADF_01688	1.86e-217	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
MKNPMADF_01689	2.47e-168	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKNPMADF_01690	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
MKNPMADF_01691	1.48e-172	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKNPMADF_01692	7.22e-282	gltT	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKNPMADF_01693	7.06e-147	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKNPMADF_01694	3.1e-218	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MKNPMADF_01695	1.39e-204	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MKNPMADF_01696	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MKNPMADF_01697	5.23e-91	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
MKNPMADF_01698	8.29e-282	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
MKNPMADF_01699	1.34e-153	yqfA	-	-	S	-	-	-	UPF0365 protein
MKNPMADF_01700	1.1e-83	-	-	-	-	-	-	-	-
MKNPMADF_01701	1e-62	yqfC	-	-	S	-	-	-	sporulation protein YqfC
MKNPMADF_01702	7.45e-278	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
MKNPMADF_01703	2.65e-220	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
MKNPMADF_01704	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
MKNPMADF_01705	1.88e-106	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKNPMADF_01706	1.82e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MKNPMADF_01707	9.11e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MKNPMADF_01708	5.78e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKNPMADF_01709	2.53e-25	-	-	-	S	-	-	-	YqzL-like protein
MKNPMADF_01710	1.88e-176	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MKNPMADF_01712	4.79e-219	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MKNPMADF_01713	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MKNPMADF_01714	5.23e-144	ccpN	-	-	K	-	-	-	CBS domain
MKNPMADF_01715	1.01e-183	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKNPMADF_01716	3.16e-102	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
MKNPMADF_01717	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKNPMADF_01718	1.45e-257	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKNPMADF_01719	6.91e-84	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
MKNPMADF_01720	3.74e-151	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MKNPMADF_01721	1.48e-250	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKNPMADF_01722	3.02e-227	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MKNPMADF_01723	1.93e-110	-	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
MKNPMADF_01724	2.66e-89	yqfQ	-	-	S	-	-	-	YqfQ-like protein
MKNPMADF_01725	2.75e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKNPMADF_01726	2.53e-208	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKNPMADF_01728	1.88e-272	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MKNPMADF_01729	3.27e-168	-	-	-	M	-	-	-	Transglycosylase SLT domain
MKNPMADF_01730	3.99e-183	zurA	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKNPMADF_01731	2.12e-179	zurM	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKNPMADF_01732	1.06e-99	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MKNPMADF_01733	4.23e-49	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
MKNPMADF_01735	1e-138	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
MKNPMADF_01736	1.97e-85	yqfX	-	-	S	-	-	-	membrane
MKNPMADF_01737	1.01e-254	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MKNPMADF_01738	8.72e-71	fimV	-	-	NU	ko:K08086,ko:K15845	ko05120,map05120	ko00000,ko00001	translation initiation factor activity
MKNPMADF_01739	7.02e-227	-	-	-	EGP	ko:K08221	-	ko00000,ko02000	Sugar (and other) transporter
MKNPMADF_01740	3.64e-193	ypuA	-	-	S	-	-	-	Secreted protein
MKNPMADF_01741	7.69e-147	-	-	-	O	-	-	-	NfeD-like C-terminal, partner-binding
MKNPMADF_01742	1.22e-246	XK27_00915	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_01743	0.0	yjbB	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
MKNPMADF_01749	1.93e-149	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
MKNPMADF_01750	3.55e-296	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
MKNPMADF_01752	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	penicillin-binding protein
MKNPMADF_01753	9.67e-99	-	-	-	S	-	-	-	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKNPMADF_01754	5.25e-79	-	-	-	-	-	-	-	-
MKNPMADF_01755	2.38e-157	-	-	-	G	-	-	-	PFAM Glycoside hydrolase 15-related
MKNPMADF_01756	6.04e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MKNPMADF_01757	7.02e-122	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKNPMADF_01758	8.93e-180	-	-	-	S	-	-	-	Integral membrane protein DUF92
MKNPMADF_01759	9.49e-238	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MKNPMADF_01760	3.2e-303	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MKNPMADF_01762	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
MKNPMADF_01763	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Bacillus/Clostridium GerA spore germination protein
MKNPMADF_01764	5.83e-87	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MKNPMADF_01765	5.26e-106	-	-	-	-	-	-	-	-
MKNPMADF_01766	1.37e-10	yqgQ	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_01767	2.54e-222	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MKNPMADF_01768	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
MKNPMADF_01769	9.41e-140	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MKNPMADF_01770	1.28e-37	-	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	ThiS family
MKNPMADF_01771	2.03e-179	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MKNPMADF_01772	3.33e-265	thiO	1.4.3.19	-	E	ko:K03153	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
MKNPMADF_01773	4.95e-180	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKNPMADF_01774	6.28e-124	-	-	-	-	-	-	-	-
MKNPMADF_01775	3.18e-238	yqgV	-	-	S	-	-	-	Thiamine-binding protein
MKNPMADF_01776	1.23e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_01777	3.32e-119	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
MKNPMADF_01778	1.05e-171	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
MKNPMADF_01779	4.16e-42	-	-	-	-	-	-	-	-
MKNPMADF_01780	3.54e-67	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_01781	2.58e-41	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MKNPMADF_01782	0.0	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKNPMADF_01783	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKNPMADF_01784	3.01e-102	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MKNPMADF_01785	3.22e-119	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKNPMADF_01786	3.7e-166	pbuO_1	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MKNPMADF_01787	3.56e-213	-	-	-	F	-	-	-	GHKL domain
MKNPMADF_01788	1.84e-214	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
MKNPMADF_01789	5.73e-120	yqjB	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_01791	9.49e-89	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
MKNPMADF_01792	1.86e-247	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
MKNPMADF_01793	6.35e-120	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MKNPMADF_01795	1.95e-89	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
MKNPMADF_01796	4.89e-102	-	-	-	S	-	-	-	Pfam Polyketide cyclase dehydrase and lipid transport
MKNPMADF_01797	7.62e-97	ykuL	-	-	S	-	-	-	CBS domain
MKNPMADF_01798	1.01e-55	-	-	-	-	-	-	-	-
MKNPMADF_01799	0.0	apr	-	-	O	-	-	-	Belongs to the peptidase S8 family
MKNPMADF_01800	1.31e-176	yibQ	-	-	S	ko:K09798	-	ko00000	protein conserved in bacteria
MKNPMADF_01801	3.57e-62	tnrA	-	-	K	-	-	-	transcriptional
MKNPMADF_01802	3.09e-66	-	-	-	-	-	-	-	-
MKNPMADF_01804	2.06e-313	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKNPMADF_01805	5.04e-162	-	-	-	P	ko:K08714	-	ko00000,ko02000	Polycystin cation channel
MKNPMADF_01806	1.99e-180	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKNPMADF_01807	1.26e-286	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKNPMADF_01808	1.63e-258	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKNPMADF_01809	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MKNPMADF_01810	4.32e-233	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
MKNPMADF_01811	5.25e-108	-	-	-	V	-	-	-	COG4767 Glycopeptide antibiotics resistance protein
MKNPMADF_01812	1.48e-69	ogt	-	-	L	ko:K07443	-	ko00000	Methyltransferase
MKNPMADF_01813	1.97e-125	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
MKNPMADF_01814	1.59e-105	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
MKNPMADF_01815	1.04e-118	-	-	-	S	-	-	-	UPF0316 protein
MKNPMADF_01816	9.59e-268	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MKNPMADF_01817	2.18e-289	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_01818	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Cache domain
MKNPMADF_01819	4.87e-252	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKNPMADF_01820	1.01e-193	-	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01821	9.45e-187	-	-	-	G	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_01822	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
MKNPMADF_01823	1.47e-179	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKNPMADF_01824	1.6e-106	-	-	-	CO	-	-	-	Thioredoxin-like
MKNPMADF_01826	2.38e-116	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
MKNPMADF_01827	6.83e-140	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MKNPMADF_01828	8.92e-111	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MKNPMADF_01829	8.77e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
MKNPMADF_01830	4.74e-211	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
MKNPMADF_01831	2.73e-284	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKNPMADF_01832	6.82e-292	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
MKNPMADF_01833	4.19e-92	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
MKNPMADF_01834	6.17e-153	-	-	-	J	-	-	-	translation release factor activity
MKNPMADF_01835	4.2e-302	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
MKNPMADF_01836	3.18e-29	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MKNPMADF_01837	1.68e-69	-	-	-	-	-	-	-	-
MKNPMADF_01838	2.22e-108	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
MKNPMADF_01839	4.73e-175	-	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MKNPMADF_01840	1.21e-268	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKNPMADF_01841	7.27e-73	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
MKNPMADF_01842	7.62e-97	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MKNPMADF_01843	7.67e-175	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKNPMADF_01844	4.62e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MKNPMADF_01845	1.18e-103	-	-	-	S	ko:K06405	-	ko00000	Pfam:SpoVA
MKNPMADF_01846	1.62e-232	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MKNPMADF_01847	5.03e-75	-	-	-	S	ko:K06407	-	ko00000	Pfam:SpoVA
MKNPMADF_01848	2.18e-138	spoVAEA	-	-	S	ko:K06407	-	ko00000	Stage V sporulation protein AE
MKNPMADF_01849	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
MKNPMADF_01850	2.81e-316	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKNPMADF_01851	4.61e-106	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKNPMADF_01852	3.88e-83	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
MKNPMADF_01853	3.17e-201	ccpC	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_01855	7.21e-261	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MKNPMADF_01856	5.99e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKNPMADF_01857	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
MKNPMADF_01858	1.24e-204	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MKNPMADF_01859	7.41e-201	hgd	1.1.1.31, 1.1.1.60	-	I	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	ko00000,ko00001,ko01000	3-hydroxyisobutyrate dehydrogenase
MKNPMADF_01860	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_01861	1.21e-241	-	-	-	I	-	-	-	3-hydroxyisobutyryl-CoA hydrolase
MKNPMADF_01862	1.75e-142	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MKNPMADF_01863	2.43e-284	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MKNPMADF_01864	4.15e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKNPMADF_01865	2.94e-103	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
MKNPMADF_01866	5.32e-160	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKNPMADF_01867	1.78e-127	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKNPMADF_01868	1.67e-135	-	-	-	K	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
MKNPMADF_01869	0.0	acoD	-	-	C	ko:K00138	ko00010,ko00620,ko01100,ko01110,ko01120,map00010,map00620,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family
MKNPMADF_01870	2.19e-216	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
MKNPMADF_01871	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKNPMADF_01872	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
MKNPMADF_01873	1.89e-59	-	-	-	S	-	-	-	ATP synthase, subunit b
MKNPMADF_01874	5.02e-158	-	-	-	S	-	-	-	membrane
MKNPMADF_01875	9.36e-60	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKNPMADF_01876	1.28e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
MKNPMADF_01877	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
MKNPMADF_01878	1.46e-73	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
MKNPMADF_01879	8.25e-270	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKNPMADF_01880	2.51e-130	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
MKNPMADF_01881	5.76e-102	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
MKNPMADF_01882	3.81e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKNPMADF_01883	5.91e-125	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MKNPMADF_01884	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
MKNPMADF_01885	1.13e-272	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MKNPMADF_01886	2.69e-167	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_01887	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_01888	1.02e-237	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_01889	4.79e-176	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MKNPMADF_01890	2.67e-124	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
MKNPMADF_01892	5e-175	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MKNPMADF_01893	3.62e-316	nox	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKNPMADF_01894	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNPMADF_01895	2.28e-57	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
MKNPMADF_01896	3.55e-223	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
MKNPMADF_01897	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKNPMADF_01898	2.26e-129	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
MKNPMADF_01901	4.37e-68	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_01902	1.44e-48	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_01904	7.6e-288	-	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyl Transferase
MKNPMADF_01905	2.38e-251	-	-	GT4	M	ko:K13678	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MKNPMADF_01906	8.81e-226	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKNPMADF_01908	9.47e-281	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MKNPMADF_01909	4.62e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MKNPMADF_01910	3.81e-183	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
MKNPMADF_01911	7.58e-213	ycgE	-	-	K	ko:K22491	-	ko00000,ko03000	MerR family transcriptional regulator
MKNPMADF_01912	9.54e-140	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKNPMADF_01913	2.22e-161	-	-	-	T	-	-	-	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_01914	0.0	-	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKNPMADF_01915	2.89e-228	-	-	-	-	-	-	-	-
MKNPMADF_01916	2.52e-302	gudB	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKNPMADF_01917	5.03e-230	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
MKNPMADF_01918	1.32e-224	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MKNPMADF_01919	3.4e-145	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
MKNPMADF_01920	4.79e-35	-	-	-	-	-	-	-	-
MKNPMADF_01921	3.72e-262	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKNPMADF_01922	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MKNPMADF_01923	0.0	metH	2.1.1.13	-	E	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
MKNPMADF_01924	6.22e-209	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
MKNPMADF_01925	1.76e-314	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
MKNPMADF_01926	5.7e-168	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MKNPMADF_01927	7.57e-135	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	1-acyl-sn-glycerol-3-phosphate acyltransferase
MKNPMADF_01928	2.39e-257	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MKNPMADF_01930	1.29e-314	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MKNPMADF_01931	2.91e-132	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKNPMADF_01932	3.58e-237	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MKNPMADF_01933	2.5e-52	-	-	-	S	-	-	-	Stage VI sporulation protein F
MKNPMADF_01934	8.81e-10	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
MKNPMADF_01935	5.33e-171	yphF	-	-	-	-	-	-	-
MKNPMADF_01936	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MKNPMADF_01937	6.78e-130	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
MKNPMADF_01938	1.85e-48	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MKNPMADF_01939	9.52e-73	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	heptaprenyl diphosphate synthase
MKNPMADF_01940	6.12e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKNPMADF_01941	8.07e-202	ubiA	2.5.1.39	-	H	ko:K03179	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MKNPMADF_01942	2.24e-203	mqnA	4.2.1.151	-	S	ko:K11782	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
MKNPMADF_01943	6.62e-231	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKNPMADF_01944	6.26e-101	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MKNPMADF_01945	4.6e-179	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
MKNPMADF_01946	2.07e-280	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKNPMADF_01947	8.18e-245	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKNPMADF_01948	3.24e-77	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MKNPMADF_01949	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKNPMADF_01950	2.3e-231	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKNPMADF_01951	1.41e-166	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
MKNPMADF_01952	2.49e-148	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosylanthranilate isomerase activity
MKNPMADF_01953	2.34e-283	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKNPMADF_01954	1.33e-187	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKNPMADF_01955	2.83e-262	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKNPMADF_01956	2.48e-254	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MKNPMADF_01957	6.7e-301	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKNPMADF_01958	1.62e-295	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKNPMADF_01959	3.4e-126	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
MKNPMADF_01960	8.38e-103	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
MKNPMADF_01961	1.48e-118	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
MKNPMADF_01962	8.39e-159	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
MKNPMADF_01963	3.57e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
MKNPMADF_01964	1e-138	ypjA	-	-	S	-	-	-	membrane
MKNPMADF_01965	2.48e-177	-	-	-	S	-	-	-	Sporulation protein YpjB (SpoYpjB)
MKNPMADF_01966	1.72e-151	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
MKNPMADF_01967	3.62e-270	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
MKNPMADF_01968	3.86e-202	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKNPMADF_01969	1.56e-78	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
MKNPMADF_01970	5.39e-180	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKNPMADF_01971	4.83e-98	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
MKNPMADF_01972	1.71e-105	-	-	-	M	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_01973	1.14e-295	hint	6.5.1.3	-	S	ko:K14415	-	ko00000,ko01000,ko03016	tRNA-splicing ligase RtcB
MKNPMADF_01974	3.33e-51	-	-	-	-	-	-	-	-
MKNPMADF_01975	4.81e-94	yyaT	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_01976	3.97e-175	-	-	-	Q	-	-	-	Methyltransferase domain
MKNPMADF_01977	3.03e-68	-	-	-	-	-	-	-	-
MKNPMADF_01978	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKNPMADF_01979	1.24e-116	-	-	-	S	-	-	-	Protein of unknown function (DUF1706)
MKNPMADF_01980	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKNPMADF_01981	5.62e-165	yodH	-	-	Q	-	-	-	Methyltransferase
MKNPMADF_01982	3.37e-193	-	-	-	M	-	-	-	3D domain
MKNPMADF_01983	4.73e-212	-	-	-	M	-	-	-	3D domain
MKNPMADF_01984	9.08e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKNPMADF_01985	4.69e-261	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MKNPMADF_01986	3.98e-188	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
MKNPMADF_01987	8.73e-132	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MKNPMADF_01988	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKNPMADF_01989	1.23e-181	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MKNPMADF_01990	1.11e-138	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MKNPMADF_01991	3.51e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MKNPMADF_01992	1.82e-74	orfX1	-	-	L	-	-	-	Transposase
MKNPMADF_01993	1.77e-160	-	-	-	L	-	-	-	Integrase core domain
MKNPMADF_01994	1.61e-145	-	-	CBM50	M	ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
MKNPMADF_01995	4.41e-289	-	-	-	S	-	-	-	Acetyltransferase
MKNPMADF_01996	3.33e-133	yvdT	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_01997	1.02e-234	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_01998	1.89e-173	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
MKNPMADF_01999	5.07e-236	ywcH1	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_02000	2.09e-213	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
MKNPMADF_02001	7.26e-265	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKNPMADF_02002	3.75e-63	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
MKNPMADF_02003	0.0	asbA	-	-	Q	-	-	-	Siderophore biosynthesis protein
MKNPMADF_02004	0.0	asbB	-	-	Q	-	-	-	IucA / IucC family
MKNPMADF_02005	1.77e-280	asbC	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	AMP-binding enzyme C-terminal domain
MKNPMADF_02006	9.05e-55	asbD	-	-	IQ	-	-	-	Phosphopantetheine attachment site
MKNPMADF_02007	3.63e-231	asbE	-	-	IQ	-	-	-	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKNPMADF_02008	7.17e-199	asbF	4.2.1.118	-	G	ko:K15652	ko00400,ko01110,ko01130,map00400,map01110,map01130	ko00000,ko00001,ko01000	Xylose isomerase-like TIM barrel
MKNPMADF_02009	2.43e-125	-	3.1.3.82, 3.1.3.83	-	E	ko:K03273	ko00540,ko01100,map00540,map01100	ko00000,ko00001,ko00002,ko01000,ko01005	D,D-heptose 1,7-bisphosphate phosphatase
MKNPMADF_02010	1.05e-309	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
MKNPMADF_02011	4.45e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MKNPMADF_02012	6.8e-161	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
MKNPMADF_02013	5.72e-188	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
MKNPMADF_02015	2.78e-71	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
MKNPMADF_02016	1.28e-06	-	-	-	S	-	-	-	Putative methionine and alanine importer, small subunit
MKNPMADF_02017	0.0	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKNPMADF_02018	2.03e-69	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MKNPMADF_02019	2.61e-52	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MKNPMADF_02020	9.78e-89	-	-	-	-	-	-	-	-
MKNPMADF_02021	2.99e-57	-	-	-	-	-	-	-	-
MKNPMADF_02022	1.21e-269	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_02023	7.87e-56	-	-	-	-	-	-	-	-
MKNPMADF_02024	1.28e-145	-	-	-	-	-	-	-	-
MKNPMADF_02025	1.14e-94	-	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
MKNPMADF_02026	1.78e-195	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MKNPMADF_02027	2.95e-117	-	-	-	K	-	-	-	Virulence activator alpha C-term
MKNPMADF_02028	5.94e-101	-	-	-	S	-	-	-	Domain of unknown function (DUF4188)
MKNPMADF_02029	1.51e-15	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
MKNPMADF_02030	2.2e-199	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_02031	1.23e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKNPMADF_02032	1.4e-119	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKNPMADF_02034	7.29e-18	-	-	-	-	-	-	-	-
MKNPMADF_02036	3.04e-38	-	-	-	K	-	-	-	Cupin
MKNPMADF_02037	2.68e-56	-	-	-	C	-	-	-	Nitroreductase family
MKNPMADF_02038	5.87e-38	-	-	-	C	-	-	-	Nitroreductase
MKNPMADF_02039	1.66e-128	-	-	-	K	-	-	-	AraC family transcriptional regulator
MKNPMADF_02040	3.06e-74	-	-	-	E	-	-	-	LysE type translocator
MKNPMADF_02041	3.87e-73	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
MKNPMADF_02042	9.82e-06	-	-	-	F	-	-	-	NUDIX domain
MKNPMADF_02043	2.58e-225	-	3.4.11.5	-	I	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
MKNPMADF_02044	1.34e-88	-	-	-	S	-	-	-	Bacterial PH domain
MKNPMADF_02045	1.67e-59	-	-	-	S	-	-	-	Belongs to the LOG family
MKNPMADF_02046	4.35e-115	-	-	-	C	-	-	-	HEAT repeats
MKNPMADF_02047	6.47e-132	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MKNPMADF_02048	1.43e-48	-	-	-	K	-	-	-	COG0202 DNA-directed RNA polymerase, alpha subunit 40 kD subunit
MKNPMADF_02049	1.98e-139	-	-	-	S	-	-	-	Golgi phosphoprotein 3 (GPP34)
MKNPMADF_02050	1.61e-191	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKNPMADF_02051	2.45e-178	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
MKNPMADF_02052	7.36e-172	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
MKNPMADF_02053	2.57e-255	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
MKNPMADF_02054	7.67e-106	yocK	-	-	T	-	-	-	general stress protein
MKNPMADF_02055	8.76e-75	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2200)
MKNPMADF_02056	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKNPMADF_02057	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKNPMADF_02058	1.47e-91	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
MKNPMADF_02059	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKNPMADF_02060	1.29e-234	opuBA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKNPMADF_02061	1.02e-188	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_02062	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MKNPMADF_02063	4.86e-174	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MKNPMADF_02064	8.33e-96	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Glycosyl hydrolase family 1
MKNPMADF_02065	4.51e-69	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
MKNPMADF_02066	4.72e-257	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNPMADF_02067	7.94e-61	licB2	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_02068	2.1e-91	-	-	-	S	ko:K07149	-	ko00000	Membrane
MKNPMADF_02069	0.0	-	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
MKNPMADF_02070	3.79e-173	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_02071	1.5e-121	-	-	-	U	-	-	-	MarC family integral membrane protein
MKNPMADF_02072	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MKNPMADF_02073	1.96e-69	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MKNPMADF_02074	1.02e-109	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKNPMADF_02075	4.22e-269	-	-	-	G	-	-	-	Transmembrane secretion effector
MKNPMADF_02076	2.04e-27	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
MKNPMADF_02077	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MKNPMADF_02078	1.08e-66	-	-	-	-	-	-	-	-
MKNPMADF_02079	6.31e-79	-	-	-	S	-	-	-	Src homology 3 domains
MKNPMADF_02080	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
MKNPMADF_02081	1.65e-246	-	-	-	E	-	-	-	Spore germination protein
MKNPMADF_02082	2.12e-251	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MKNPMADF_02084	0.0	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKNPMADF_02085	1.65e-212	-	-	-	NT	-	-	-	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
MKNPMADF_02086	8.13e-82	-	-	-	-	-	-	-	-
MKNPMADF_02087	2.86e-81	-	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
MKNPMADF_02088	0.0	-	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Thiamine pyrophosphate enzyme, central domain
MKNPMADF_02089	1.32e-223	-	-	-	S	-	-	-	Oxidoreductase
MKNPMADF_02090	1.29e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MKNPMADF_02091	5.5e-51	-	-	-	-	-	-	-	-
MKNPMADF_02092	5.79e-88	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids
MKNPMADF_02093	1.53e-63	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKNPMADF_02094	2.87e-126	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MKNPMADF_02095	3.2e-07	cotD	-	-	S	ko:K06327	-	ko00000	Inner spore coat protein D
MKNPMADF_02096	3.28e-277	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
MKNPMADF_02097	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MKNPMADF_02098	0.0	pepF	-	-	E	-	-	-	oligoendopeptidase F
MKNPMADF_02099	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
MKNPMADF_02100	2.3e-237	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MKNPMADF_02101	5.46e-259	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MKNPMADF_02102	2.07e-116	-	-	-	-	-	-	-	-
MKNPMADF_02103	5.9e-137	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
MKNPMADF_02104	5.03e-229	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKNPMADF_02105	1.31e-24	-	-	-	-	-	-	-	-
MKNPMADF_02106	7.58e-188	ycsE	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKNPMADF_02107	1.1e-108	-	-	-	-	-	-	-	-
MKNPMADF_02108	2.9e-05	-	-	-	S	ko:K06376	-	ko00000	Spo0E like sporulation regulatory protein
MKNPMADF_02109	1.43e-198	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKNPMADF_02110	1.54e-80	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
MKNPMADF_02111	8.96e-51	-	-	-	-	-	-	-	-
MKNPMADF_02112	1.16e-146	ypjP	-	-	S	-	-	-	YpjP-like protein
MKNPMADF_02113	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MKNPMADF_02114	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
MKNPMADF_02116	1.12e-196	telA	-	-	P	-	-	-	Belongs to the TelA family
MKNPMADF_02117	1.34e-209	-	-	-	-	-	-	-	-
MKNPMADF_02118	2.09e-244	-	-	-	S	-	-	-	Protein of unknown function (DUF2777)
MKNPMADF_02119	8.45e-304	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
MKNPMADF_02120	5.84e-110	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MKNPMADF_02121	2.16e-39	-	-	-	-	-	-	-	-
MKNPMADF_02122	2.63e-195	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
MKNPMADF_02123	4.86e-176	-	-	-	T	-	-	-	Calcineurin-like phosphoesterase superfamily domain
MKNPMADF_02124	6.98e-95	-	-	-	CO	-	-	-	Thioredoxin-like
MKNPMADF_02125	3.12e-100	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
MKNPMADF_02126	3.7e-70	yusE	-	-	CO	-	-	-	cell redox homeostasis
MKNPMADF_02127	1.16e-214	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKNPMADF_02128	5.49e-124	yraA	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MKNPMADF_02129	7.48e-299	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKNPMADF_02130	2.9e-26	-	-	-	-	-	-	-	-
MKNPMADF_02131	9.46e-67	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
MKNPMADF_02132	1.29e-111	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MKNPMADF_02134	2.05e-202	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
MKNPMADF_02135	1.41e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKNPMADF_02136	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKNPMADF_02137	0.0	ypbR	-	-	S	-	-	-	Dynamin family
MKNPMADF_02138	1.45e-157	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKNPMADF_02139	1.14e-161	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
MKNPMADF_02140	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
MKNPMADF_02141	1.59e-104	ypmB	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_02142	8.74e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
MKNPMADF_02144	1.96e-311	mtaD	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MKNPMADF_02145	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MKNPMADF_02146	2.89e-223	-	-	-	S	-	-	-	Tetratricopeptide repeat
MKNPMADF_02147	5.68e-83	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MKNPMADF_02148	1.64e-209	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MKNPMADF_02149	3.28e-193	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MKNPMADF_02150	4.28e-226	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKNPMADF_02151	1.71e-246	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKNPMADF_02152	8.93e-246	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
MKNPMADF_02153	2.3e-161	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
MKNPMADF_02154	1.59e-25	-	-	-	-	-	-	-	-
MKNPMADF_02156	1.5e-187	-	-	-	S	-	-	-	Nucleotidyltransferase domain
MKNPMADF_02158	2.86e-210	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
MKNPMADF_02159	1.11e-230	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MKNPMADF_02160	7.66e-136	-	-	-	S	-	-	-	CAAX protease self-immunity
MKNPMADF_02161	7.67e-162	-	-	-	K	ko:K11922	-	ko00000,ko03000	UTRA
MKNPMADF_02162	1.96e-310	glvA	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKNPMADF_02163	7.68e-172	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides
MKNPMADF_02164	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MKNPMADF_02166	5.73e-23	-	-	-	-	-	-	-	-
MKNPMADF_02170	1.04e-106	-	-	-	-	-	-	-	-
MKNPMADF_02171	5.53e-159	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MKNPMADF_02172	0.0	-	4.3.2.2, 5.5.1.2	-	F	ko:K01756,ko:K01857	ko00230,ko00250,ko00362,ko01100,ko01110,ko01120,ko01130,ko01220,map00230,map00250,map00362,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko00002,ko01000	Adenylosuccinate lyase C-terminus
MKNPMADF_02173	0.0	-	2.7.1.199, 2.7.1.208	-	G	ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02060,map00010,map00500,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_02174	2.79e-171	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
MKNPMADF_02176	1.1e-32	-	-	-	-	-	-	-	-
MKNPMADF_02177	1.38e-68	-	-	-	S	-	-	-	DinB superfamily
MKNPMADF_02178	5.49e-48	-	-	-	L	ko:K07483	-	ko00000	Transposase
MKNPMADF_02179	2.6e-125	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
MKNPMADF_02180	0.0	-	-	-	L	-	-	-	Transposase
MKNPMADF_02181	2.28e-172	-	-	-	L	-	-	-	IstB-like ATP binding protein
MKNPMADF_02188	3.95e-12	-	-	-	S	-	-	-	DNA-dependent transcription, initiation
MKNPMADF_02189	8.18e-124	-	-	-	S	-	-	-	Pfam:Peptidase_M78
MKNPMADF_02191	3.35e-293	-	-	-	S	-	-	-	membrane
MKNPMADF_02192	7.3e-271	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
MKNPMADF_02194	3.73e-90	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
MKNPMADF_02195	2.99e-143	mucD	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKNPMADF_02196	3.3e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
MKNPMADF_02197	1.15e-160	bshB2	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
MKNPMADF_02198	2.96e-212	-	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	Helix-hairpin-helix class 2 (Pol1 family) motifs
MKNPMADF_02199	7.25e-133	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_02200	6.1e-116	yocC	-	-	-	-	-	-	-
MKNPMADF_02201	1.32e-74	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
MKNPMADF_02202	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKNPMADF_02203	1.46e-198	yvgN	-	-	S	-	-	-	reductase
MKNPMADF_02204	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MKNPMADF_02205	2.42e-26	-	-	-	L	-	-	-	Transposase IS200 like
MKNPMADF_02206	9.15e-45	yozC	-	-	-	-	-	-	-
MKNPMADF_02207	2.89e-251	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MKNPMADF_02208	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MKNPMADF_02210	2.6e-233	-	-	-	Q	-	-	-	O-methyltransferase
MKNPMADF_02211	2.16e-150	-	-	-	M	ko:K21471,ko:K21472	-	ko00000,ko01000,ko01002,ko01011	lytic transglycosylase activity
MKNPMADF_02213	2.17e-97	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
MKNPMADF_02214	0.0	-	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKNPMADF_02216	3.78e-213	sagG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKNPMADF_02217	5.97e-158	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKNPMADF_02218	1.93e-146	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
MKNPMADF_02219	3.03e-238	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_02220	3.83e-132	-	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
MKNPMADF_02221	9.26e-123	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MKNPMADF_02222	6.34e-154	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MKNPMADF_02223	7.73e-99	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
MKNPMADF_02224	5.27e-161	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MKNPMADF_02225	1.69e-297	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
MKNPMADF_02226	2.92e-312	agcS	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MKNPMADF_02227	4.11e-52	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MKNPMADF_02228	4.7e-57	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
MKNPMADF_02229	2.19e-67	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MKNPMADF_02230	2.33e-142	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
MKNPMADF_02231	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKNPMADF_02232	7.16e-236	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MKNPMADF_02233	1.13e-57	-	-	-	S	-	-	-	DNA alkylation repair protein
MKNPMADF_02234	8.19e-267	-	-	-	I	ko:K01066	-	ko00000,ko01000	COG0657 Esterase lipase
MKNPMADF_02235	6.64e-114	msrA	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKNPMADF_02236	7.87e-66	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MKNPMADF_02238	2.72e-201	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
MKNPMADF_02239	6.75e-216	-	3.4.13.19	-	E	ko:K01273	-	ko00000,ko00537,ko01000,ko01002,ko04147	COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog
MKNPMADF_02240	1.76e-90	hspX	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MKNPMADF_02241	9.86e-44	-	-	-	S	-	-	-	YppG-like protein
MKNPMADF_02242	5.18e-31	-	-	-	-	-	-	-	-
MKNPMADF_02243	3.93e-294	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
MKNPMADF_02244	9.32e-189	-	-	-	I	-	-	-	Hydrolase
MKNPMADF_02245	5.83e-230	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MKNPMADF_02246	4.8e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MKNPMADF_02247	1.62e-194	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKNPMADF_02248	2.92e-98	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MKNPMADF_02249	0.0	spoVK_1	-	-	O	-	-	-	stage V sporulation protein K
MKNPMADF_02250	1.95e-175	-	-	-	P	ko:K07245	-	ko00000,ko02000	Copper resistance protein D
MKNPMADF_02251	3.93e-17	sspN	-	-	S	ko:K06431	-	ko00000	Small acid-soluble spore protein N family
MKNPMADF_02252	2.3e-06	-	-	-	S	-	-	-	Fur-regulated basic protein B
MKNPMADF_02254	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MKNPMADF_02256	1.22e-19	-	-	-	-	-	-	-	-
MKNPMADF_02257	2.41e-106	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
MKNPMADF_02258	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_02259	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
MKNPMADF_02260	8.21e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
MKNPMADF_02261	5.21e-93	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
MKNPMADF_02262	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKNPMADF_02263	2.51e-46	ynzC	-	-	S	-	-	-	UPF0291 protein
MKNPMADF_02264	1.62e-148	yneB	-	-	L	-	-	-	resolvase
MKNPMADF_02266	8.11e-145	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKNPMADF_02267	3.58e-282	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
MKNPMADF_02269	1.48e-271	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKNPMADF_02271	2.59e-119	-	-	-	FG	-	-	-	Domain of unknown function (DUF4269)
MKNPMADF_02272	2.21e-64	-	-	-	-	-	-	-	-
MKNPMADF_02273	1.97e-174	-	-	-	K	-	-	-	helix_turn_helix isocitrate lyase regulation
MKNPMADF_02274	1.18e-178	-	-	-	Q	-	-	-	Domain of unknown function (DUF2437)
MKNPMADF_02275	0.0	glcB	2.3.3.9	-	C	ko:K01638	ko00620,ko00630,ko01100,ko01110,ko01120,ko01200,map00620,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MKNPMADF_02276	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
MKNPMADF_02277	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MKNPMADF_02278	2.15e-284	-	-	-	C	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	FAD binding domain
MKNPMADF_02279	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MKNPMADF_02280	4.83e-312	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MKNPMADF_02281	1.66e-219	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
MKNPMADF_02282	5.03e-232	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKNPMADF_02283	1.24e-47	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MKNPMADF_02284	3.47e-215	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKNPMADF_02285	1.73e-172	-	-	-	J	-	-	-	Putative SAM-dependent methyltransferase
MKNPMADF_02286	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKNPMADF_02287	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKNPMADF_02288	1.13e-133	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
MKNPMADF_02289	3.04e-86	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
MKNPMADF_02290	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MKNPMADF_02291	1.7e-194	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
MKNPMADF_02292	7.82e-51	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
MKNPMADF_02293	1.76e-190	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
MKNPMADF_02294	3.81e-293	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MKNPMADF_02295	1.81e-147	-	-	-	L	-	-	-	DNA recombination
MKNPMADF_02296	8.1e-10	-	-	-	-	-	-	-	-
MKNPMADF_02297	0.0	-	-	-	L	-	-	-	AAA domain
MKNPMADF_02298	3.32e-239	-	-	-	L	-	-	-	Calcineurin-like phosphoesterase superfamily domain
MKNPMADF_02299	3.46e-242	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKNPMADF_02300	0.0	deaD	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKNPMADF_02301	9.93e-285	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MKNPMADF_02302	2.85e-128	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKNPMADF_02303	4.82e-180	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
MKNPMADF_02304	5.43e-180	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
MKNPMADF_02305	1.34e-51	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
MKNPMADF_02306	5.32e-153	ymfI	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_02307	7.42e-314	ymfH	-	-	S	-	-	-	zinc protease
MKNPMADF_02308	6.05e-290	albE	-	-	S	-	-	-	Peptidase M16
MKNPMADF_02309	4.82e-165	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_02310	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MKNPMADF_02311	1.37e-06	-	-	-	S	-	-	-	YlzJ-like protein
MKNPMADF_02312	3.79e-165	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
MKNPMADF_02313	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKNPMADF_02314	7.16e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKNPMADF_02315	2.52e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MKNPMADF_02316	1.03e-243	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKNPMADF_02317	1.32e-138	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MKNPMADF_02318	4.5e-203	spoVFA	-	-	E	ko:K06410	-	ko00000	subunit a
MKNPMADF_02319	1.52e-48	ymxH	-	-	S	-	-	-	YlmC YmxH family
MKNPMADF_02320	5.66e-278	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
MKNPMADF_02321	7.88e-244	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
MKNPMADF_02322	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MKNPMADF_02323	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKNPMADF_02324	2.77e-222	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MKNPMADF_02325	2.88e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKNPMADF_02326	2.49e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKNPMADF_02327	2.96e-55	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
MKNPMADF_02328	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKNPMADF_02329	3.53e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
MKNPMADF_02330	1.66e-56	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
MKNPMADF_02331	3.99e-257	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MKNPMADF_02332	1.1e-103	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MKNPMADF_02333	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKNPMADF_02334	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKNPMADF_02335	3.5e-290	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MKNPMADF_02336	7.52e-263	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MKNPMADF_02337	3.35e-175	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MKNPMADF_02338	1.76e-186	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKNPMADF_02339	3.08e-115	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKNPMADF_02340	3.37e-160	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MKNPMADF_02341	2.05e-199	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKNPMADF_02342	2.3e-170	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MKNPMADF_02343	1.99e-05	ylxL	-	-	-	-	-	-	-
MKNPMADF_02344	1e-170	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKNPMADF_02345	4.45e-109	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MKNPMADF_02346	1.02e-136	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MKNPMADF_02347	9.45e-208	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MKNPMADF_02348	2.84e-123	-	-	-	-	-	-	-	-
MKNPMADF_02349	1.37e-222	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
MKNPMADF_02350	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKNPMADF_02351	2.3e-237	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MKNPMADF_02352	2.52e-167	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
MKNPMADF_02353	8.01e-54	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
MKNPMADF_02354	5.99e-145	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
MKNPMADF_02355	4.36e-133	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
MKNPMADF_02356	1.05e-77	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
MKNPMADF_02357	3.16e-261	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MKNPMADF_02358	7.63e-224	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKNPMADF_02359	9.32e-92	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
MKNPMADF_02360	1.26e-37	flbD	-	-	N	ko:K02385	-	ko00000,ko02035	protein, possibly involved in motility
MKNPMADF_02361	2.96e-174	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
MKNPMADF_02362	1.05e-93	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
MKNPMADF_02363	1.95e-259	-	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein FliK
MKNPMADF_02365	5.98e-90	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
MKNPMADF_02366	3.41e-312	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MKNPMADF_02367	9.58e-103	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
MKNPMADF_02368	1.32e-227	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MKNPMADF_02369	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
MKNPMADF_02370	2.85e-51	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
MKNPMADF_02371	5.12e-96	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
MKNPMADF_02372	2.38e-86	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MKNPMADF_02373	2.27e-174	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MKNPMADF_02374	1.13e-295	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKNPMADF_02375	2.12e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKNPMADF_02376	1.53e-213	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
MKNPMADF_02377	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKNPMADF_02378	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKNPMADF_02379	2.49e-215	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
MKNPMADF_02380	3.09e-215	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MKNPMADF_02381	5.15e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MKNPMADF_02382	6.44e-94	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	FlhB HrpN YscU SpaS Family
MKNPMADF_02384	1.54e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKNPMADF_02386	3.3e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKNPMADF_02387	2.39e-132	sipS	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MKNPMADF_02388	2.69e-11	-	-	-	-	-	-	-	-
MKNPMADF_02389	5.47e-110	MA20_20600	1.14.17.3	-	CO	ko:K00504	-	ko00000,ko01000	amine dehydrogenase activity
MKNPMADF_02390	4.61e-147	-	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	amidotransferase, A subunit
MKNPMADF_02392	1.86e-93	-	4.1.2.52	-	G	ko:K02510	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
MKNPMADF_02394	2.95e-262	aldHT_2	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
MKNPMADF_02395	3.42e-227	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
MKNPMADF_02396	1.03e-66	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_02397	3.3e-148	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
MKNPMADF_02398	1.62e-195	-	-	-	E	-	-	-	aminopeptidase
MKNPMADF_02399	6.63e-76	-	-	-	J	-	-	-	YjgF/chorismate_mutase-like, putative endoribonuclease
MKNPMADF_02400	6.89e-154	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Dihydrodipicolinate synthetase family
MKNPMADF_02401	1.76e-09	-	-	-	L	ko:K07491	-	ko00000	Transposase
MKNPMADF_02402	1.35e-73	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKNPMADF_02403	0.0	-	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl tRNA synthetase N terminal dom
MKNPMADF_02404	2.12e-167	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MKNPMADF_02405	2.18e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKNPMADF_02406	2.5e-90	-	-	-	S	-	-	-	YlqD protein
MKNPMADF_02407	1.11e-45	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MKNPMADF_02408	7.93e-59	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MKNPMADF_02409	9.78e-312	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKNPMADF_02410	5.45e-68	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKNPMADF_02411	3.38e-226	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKNPMADF_02412	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MKNPMADF_02413	1.67e-14	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
MKNPMADF_02414	1.55e-177	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKNPMADF_02415	1.35e-42	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKNPMADF_02416	1.16e-161	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MKNPMADF_02417	3.45e-214	fabD	2.3.1.39	-	I	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	malonyl CoA-acyl carrier protein transacylase
MKNPMADF_02418	2.9e-228	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKNPMADF_02419	2.17e-127	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MKNPMADF_02420	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKNPMADF_02421	1.55e-195	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MKNPMADF_02422	1.51e-155	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
MKNPMADF_02423	2.19e-190	yitS	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_02424	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
MKNPMADF_02425	1.81e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_02426	4.09e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MKNPMADF_02427	2.6e-149	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MKNPMADF_02428	2.01e-210	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKNPMADF_02429	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MKNPMADF_02430	5.6e-170	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MKNPMADF_02431	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKNPMADF_02432	1.43e-224	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKNPMADF_02433	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKNPMADF_02434	3.81e-274	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKNPMADF_02435	2.67e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKNPMADF_02436	9.15e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MKNPMADF_02437	1.15e-52	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
MKNPMADF_02438	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MKNPMADF_02439	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
MKNPMADF_02440	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MKNPMADF_02442	1.54e-145	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKNPMADF_02443	1.64e-138	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKNPMADF_02444	2.36e-157	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKNPMADF_02445	2.73e-211	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKNPMADF_02446	4.28e-179	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MKNPMADF_02447	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
MKNPMADF_02448	2.25e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MKNPMADF_02449	7.03e-306	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKNPMADF_02450	4.18e-207	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MKNPMADF_02451	5.35e-288	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
MKNPMADF_02452	1.55e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKNPMADF_02453	2.76e-217	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MKNPMADF_02454	3.71e-95	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKNPMADF_02455	1.4e-140	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
MKNPMADF_02456	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKNPMADF_02457	1.53e-95	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
MKNPMADF_02458	3.38e-173	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
MKNPMADF_02459	7.03e-58	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
MKNPMADF_02460	1.13e-91	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKNPMADF_02461	2.77e-151	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MKNPMADF_02462	2.85e-184	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
MKNPMADF_02463	5.13e-61	ylmC	-	-	S	-	-	-	sporulation protein
MKNPMADF_02464	1.05e-180	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKNPMADF_02465	8.95e-161	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MKNPMADF_02466	8.42e-205	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MKNPMADF_02467	3.4e-240	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKNPMADF_02468	4.62e-292	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKNPMADF_02470	4.2e-165	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKNPMADF_02471	1.47e-246	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKNPMADF_02472	2.89e-308	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKNPMADF_02473	1.16e-216	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKNPMADF_02474	3.53e-310	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKNPMADF_02475	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKNPMADF_02476	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
MKNPMADF_02478	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MKNPMADF_02479	2.26e-62	ftsL	-	-	D	-	-	-	cell division protein FtsL
MKNPMADF_02480	2.98e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKNPMADF_02481	4.81e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MKNPMADF_02482	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MKNPMADF_02484	3.84e-184	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKNPMADF_02485	5.16e-120	ylbP	-	-	K	-	-	-	n-acetyltransferase
MKNPMADF_02486	4.09e-98	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MKNPMADF_02487	7.12e-36	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MKNPMADF_02488	3.32e-119	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
MKNPMADF_02489	3.06e-282	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MKNPMADF_02490	2.96e-243	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MKNPMADF_02491	1.17e-177	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MKNPMADF_02492	1.04e-271	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
MKNPMADF_02493	7.39e-108	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKNPMADF_02494	2.67e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
MKNPMADF_02495	4.19e-84	-	-	-	S	-	-	-	Methylthioribose kinase
MKNPMADF_02496	4.89e-63	ylbG	-	-	S	-	-	-	UPF0298 protein
MKNPMADF_02497	6.75e-91	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
MKNPMADF_02498	2.29e-177	-	-	-	HJ	ko:K05844	-	ko00000,ko01000,ko03009	Prokaryotic glutathione synthetase, ATP-grasp domain
MKNPMADF_02499	7.5e-43	ylbE	-	-	S	-	-	-	YlbE-like protein
MKNPMADF_02500	1.09e-91	ylbD	-	-	S	-	-	-	Putative coat protein
MKNPMADF_02501	1.38e-108	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	protein, possibly involved in aromatic compounds catabolism
MKNPMADF_02502	1.31e-248	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
MKNPMADF_02503	7.74e-83	ylbA	-	-	S	-	-	-	YugN-like family
MKNPMADF_02504	1.95e-109	-	-	-	-	-	-	-	-
MKNPMADF_02505	2.65e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
MKNPMADF_02506	2.95e-68	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MKNPMADF_02507	7.21e-143	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MKNPMADF_02508	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MKNPMADF_02509	2.38e-253	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MKNPMADF_02510	3.05e-203	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MKNPMADF_02511	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKNPMADF_02512	1.92e-56	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
MKNPMADF_02513	3.07e-119	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MKNPMADF_02514	0.0	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
MKNPMADF_02515	1.3e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_02516	3.51e-67	ylaH	-	-	S	-	-	-	YlaH-like protein
MKNPMADF_02517	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MKNPMADF_02518	1.13e-17	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
MKNPMADF_02519	9.17e-210	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MKNPMADF_02520	1.2e-194	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
MKNPMADF_02521	7.8e-149	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
MKNPMADF_02522	2.47e-52	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MKNPMADF_02523	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
MKNPMADF_02524	1.54e-268	-	-	-	O	-	-	-	Peptidase family M48
MKNPMADF_02525	7.93e-167	pdaA_2	3.5.1.104	-	G	ko:K01567,ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
MKNPMADF_02526	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
MKNPMADF_02527	1.1e-85	-	-	-	CO	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	cell redox homeostasis
MKNPMADF_02528	2.82e-206	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_02529	7.93e-222	-	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_02530	0.0	appA_2	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_02531	3.71e-236	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_02532	1.77e-238	appD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_02533	1.76e-207	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase (reverse transcriptase)
MKNPMADF_02534	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKNPMADF_02535	6.67e-248	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKNPMADF_02536	2.48e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKNPMADF_02537	7.59e-256	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKNPMADF_02538	2.94e-131	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
MKNPMADF_02539	1.23e-12	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
MKNPMADF_02540	4.29e-130	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKNPMADF_02541	1.81e-41	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MKNPMADF_02542	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKNPMADF_02543	2.58e-147	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
MKNPMADF_02544	7.23e-107	ykuV	-	-	CO	-	-	-	thiol-disulfide
MKNPMADF_02545	3.15e-131	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
MKNPMADF_02546	3.84e-162	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
MKNPMADF_02547	1.46e-50	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
MKNPMADF_02548	2.75e-267	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKNPMADF_02549	4.33e-279	-	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-III
MKNPMADF_02550	2.28e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKNPMADF_02551	5.05e-186	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MKNPMADF_02552	3.41e-234	-	-	-	T	-	-	-	Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNPMADF_02553	3.35e-248	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
MKNPMADF_02554	2.69e-117	copC	-	-	S	ko:K07156	-	ko00000,ko02000	CopC domain
MKNPMADF_02555	1.29e-226	ytvI	-	-	S	-	-	-	AI-2E family transporter
MKNPMADF_02556	1.29e-131	yhfK	-	-	GM	-	-	-	NmrA-like family
MKNPMADF_02557	5.15e-272	-	-	-	E	-	-	-	Peptidase family M28
MKNPMADF_02558	3.74e-241	-	-	-	C	-	-	-	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MKNPMADF_02560	1.5e-124	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MKNPMADF_02561	1.35e-38	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Heavy-metal-associated domain
MKNPMADF_02562	6.7e-62	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
MKNPMADF_02563	3.94e-41	-	-	-	-	-	-	-	-
MKNPMADF_02564	7.18e-186	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKNPMADF_02565	1.09e-95	-	-	-	S	-	-	-	Transcriptional regulator
MKNPMADF_02566	4.13e-35	-	-	-	-	-	-	-	-
MKNPMADF_02567	3.65e-68	-	-	-	S	-	-	-	dUTPase
MKNPMADF_02571	2.87e-88	-	-	-	Q	-	-	-	DNA (cytosine-5-)-methyltransferase activity
MKNPMADF_02573	6.41e-49	-	-	-	S	-	-	-	Protein of unknwon function (DUF3310)
MKNPMADF_02574	5.13e-30	-	-	-	-	-	-	-	-
MKNPMADF_02575	5.47e-125	-	-	-	L	-	-	-	ERCC4 domain
MKNPMADF_02576	7.84e-80	-	-	-	-	-	-	-	-
MKNPMADF_02577	0.0	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
MKNPMADF_02578	2.67e-101	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MKNPMADF_02579	2.33e-212	-	-	-	D	-	-	-	AAA domain
MKNPMADF_02580	6.2e-109	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
MKNPMADF_02581	1.85e-26	-	-	-	-	-	-	-	-
MKNPMADF_02583	3.24e-60	-	-	-	-	-	-	-	-
MKNPMADF_02585	3.34e-81	-	-	-	S	ko:K07741	-	ko00000	Phage regulatory protein Rha (Phage_pRha)
MKNPMADF_02587	5.19e-18	-	-	-	-	-	-	-	-
MKNPMADF_02588	2.48e-30	-	-	-	-	-	-	-	-
MKNPMADF_02589	5.88e-61	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_02590	4.22e-109	-	-	-	E	-	-	-	Zn peptidase
MKNPMADF_02593	8.52e-29	-	-	-	-	-	-	-	-
MKNPMADF_02594	1e-51	yqiX	-	-	S	-	-	-	YolD-like protein
MKNPMADF_02595	8e-175	ligB	6.5.1.1, 6.5.1.6, 6.5.1.7	-	L	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	ko00000,ko00001,ko01000,ko03032,ko03400	ATP-dependent DNA ligase
MKNPMADF_02598	1.28e-123	-	3.5.1.28	-	V	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
MKNPMADF_02599	1.15e-82	-	-	-	S	-	-	-	Bacteriophage holin family
MKNPMADF_02600	1.09e-298	-	-	-	L	-	-	-	Prophage endopeptidase tail
MKNPMADF_02604	0.0	-	-	-	-	-	-	-	-
MKNPMADF_02605	0.0	-	-	-	M	-	-	-	Peptidase_G2, IMC autoproteolytic cleavage domain
MKNPMADF_02606	7.03e-192	-	-	-	S	-	-	-	Phage tail protein
MKNPMADF_02607	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
MKNPMADF_02610	5.98e-142	-	-	-	N	-	-	-	phage major tail protein, phi13 family
MKNPMADF_02611	2.25e-72	-	-	-	-	-	-	-	-
MKNPMADF_02612	5.58e-15	-	-	-	S	-	-	-	TIGRFAM phage protein, HK97 gp10 family
MKNPMADF_02613	5.64e-75	-	-	-	S	-	-	-	Phage head-tail joining protein
MKNPMADF_02614	6.47e-64	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MKNPMADF_02615	2.65e-79	-	-	-	N	-	-	-	Bacterial Ig-like domain 2
MKNPMADF_02616	6.81e-291	-	-	-	S	-	-	-	capsid protein
MKNPMADF_02617	1.7e-122	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
MKNPMADF_02618	7.1e-277	-	-	-	S	-	-	-	Phage portal protein
MKNPMADF_02619	5.39e-35	-	-	-	-	-	-	-	-
MKNPMADF_02620	0.0	-	-	-	S	-	-	-	Terminase
MKNPMADF_02621	7.13e-110	-	-	-	L	-	-	-	phage terminase small subunit
MKNPMADF_02622	1.91e-89	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
MKNPMADF_02626	1.24e-87	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKNPMADF_02628	3.78e-76	-	-	-	-	-	-	-	-
MKNPMADF_02629	2.39e-98	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
MKNPMADF_02630	2.82e-280	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKNPMADF_02631	1.82e-230	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKNPMADF_02632	4.02e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKNPMADF_02633	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MKNPMADF_02634	3.44e-261	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKNPMADF_02635	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
MKNPMADF_02636	5.51e-47	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
MKNPMADF_02637	2.54e-139	-	-	-	M	-	-	-	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKNPMADF_02638	4.46e-183	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MKNPMADF_02639	6.95e-300	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
MKNPMADF_02640	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MKNPMADF_02641	2.64e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MKNPMADF_02642	1.01e-187	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
MKNPMADF_02643	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKNPMADF_02644	1.28e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MKNPMADF_02645	2.03e-47	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKNPMADF_02646	2.98e-270	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKNPMADF_02647	3.22e-85	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKNPMADF_02648	2.43e-86	yqhY	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_02649	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MKNPMADF_02650	2.63e-98	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKNPMADF_02651	3.08e-74	-	-	-	-	-	-	-	-
MKNPMADF_02652	1.41e-115	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
MKNPMADF_02653	2.88e-144	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
MKNPMADF_02654	2.2e-118	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
MKNPMADF_02655	2.67e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
MKNPMADF_02656	6.3e-54	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
MKNPMADF_02657	1.98e-40	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
MKNPMADF_02658	4.86e-107	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
MKNPMADF_02659	1.03e-211	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
MKNPMADF_02660	2.71e-48	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
MKNPMADF_02661	7.6e-61	-	-	-	S	-	-	-	YfzA-like protein
MKNPMADF_02662	8.98e-122	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKNPMADF_02663	7.96e-127	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKNPMADF_02664	3.62e-247	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MKNPMADF_02665	6.03e-114	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
MKNPMADF_02666	3.77e-74	-	-	-	-	-	-	-	-
MKNPMADF_02667	3.17e-208	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
MKNPMADF_02668	3.81e-100	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MKNPMADF_02669	1.43e-250	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
MKNPMADF_02670	7.77e-199	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MKNPMADF_02671	0.0	uvrD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKNPMADF_02672	3.56e-196	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MKNPMADF_02673	1.34e-81	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
MKNPMADF_02674	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKNPMADF_02675	9.28e-317	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MKNPMADF_02676	2.23e-258	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
MKNPMADF_02677	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKNPMADF_02678	8.12e-196	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
MKNPMADF_02680	7.25e-153	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
MKNPMADF_02681	2.65e-48	B4168_0554	-	-	S	-	-	-	Protein of unknown function (DUF2626)
MKNPMADF_02684	2.01e-102	-	-	-	-	-	-	-	-
MKNPMADF_02686	1.46e-91	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
MKNPMADF_02687	3.92e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
MKNPMADF_02688	3.58e-55	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
MKNPMADF_02698	1.81e-230	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
MKNPMADF_02699	4.07e-225	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MKNPMADF_02700	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKNPMADF_02701	1.03e-72	-	-	-	-	-	-	-	-
MKNPMADF_02702	3.22e-97	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
MKNPMADF_02703	1.24e-07	-	-	-	-	-	-	-	-
MKNPMADF_02705	1.7e-174	-	-	-	-	-	-	-	-
MKNPMADF_02706	9.98e-157	-	-	-	-	-	-	-	-
MKNPMADF_02707	3.28e-178	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
MKNPMADF_02708	2.43e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF1360)
MKNPMADF_02709	8.28e-177	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MKNPMADF_02710	7.23e-208	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MKNPMADF_02711	7.48e-193	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKNPMADF_02712	4.17e-142	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
MKNPMADF_02713	3.08e-81	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
MKNPMADF_02714	9.57e-120	yjbK	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_02715	1.32e-132	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MKNPMADF_02716	1.67e-95	yjbI	-	-	S	ko:K06886	-	ko00000	COG2346 Truncated hemoglobins
MKNPMADF_02717	4.97e-219	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
MKNPMADF_02719	4.69e-254	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MKNPMADF_02720	1.11e-147	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MKNPMADF_02721	2.03e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKNPMADF_02723	6.86e-126	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_02724	6.91e-296	-	-	-	S	-	-	-	Putative glycosyl hydrolase domain
MKNPMADF_02725	1.9e-12	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
MKNPMADF_02726	3.02e-144	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
MKNPMADF_02727	1.76e-127	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MKNPMADF_02728	9.58e-132	-	-	-	CO	-	-	-	Redoxin
MKNPMADF_02730	1.56e-232	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
MKNPMADF_02731	1.94e-15	-	-	-	-	-	-	-	-
MKNPMADF_02732	2.71e-181	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
MKNPMADF_02733	5.49e-197	yjaZ	-	-	O	-	-	-	Zn-dependent protease
MKNPMADF_02734	2.48e-175	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
MKNPMADF_02735	1.75e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MKNPMADF_02736	1.6e-171	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
MKNPMADF_02738	4.53e-132	-	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
MKNPMADF_02740	0.0	-	2.7.7.19, 2.7.7.72	-	J	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	Poly A polymerase head domain
MKNPMADF_02741	7.41e-294	fabF	2.3.1.179	-	I	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKNPMADF_02742	8.46e-212	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKNPMADF_02744	5.14e-19	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	Competence protein ComG
MKNPMADF_02745	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MKNPMADF_02746	2.18e-184	-	5.1.3.2	-	GM	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MKNPMADF_02747	1.73e-150	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
MKNPMADF_02748	3.33e-215	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKNPMADF_02749	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
MKNPMADF_02750	2.17e-266	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MKNPMADF_02751	3.95e-272	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
MKNPMADF_02752	5.5e-165	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MKNPMADF_02753	1.41e-284	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKNPMADF_02754	2.11e-249	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKNPMADF_02755	9.21e-212	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
MKNPMADF_02756	1.24e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKNPMADF_02757	2.72e-102	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_02758	4.2e-139	-	-	-	-	-	-	-	-
MKNPMADF_02759	4.35e-282	ywqB	-	-	S	-	-	-	zinc ion binding
MKNPMADF_02760	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
MKNPMADF_02762	1.4e-16	-	-	-	S	-	-	-	Intracellular proteinase inhibitor
MKNPMADF_02763	8.93e-187	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKNPMADF_02764	4.15e-187	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MKNPMADF_02765	9.73e-55	-	-	-	-	-	-	-	-
MKNPMADF_02766	5.57e-83	ytwF	-	-	P	-	-	-	Sulfurtransferase
MKNPMADF_02767	5.62e-116	-	-	-	-	-	-	-	-
MKNPMADF_02768	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MKNPMADF_02769	3.16e-196	ykgA	-	-	E	-	-	-	Amidinotransferase
MKNPMADF_02770	1.31e-63	-	-	-	S	-	-	-	IDEAL
MKNPMADF_02771	0.0	asnH	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MKNPMADF_02772	3e-88	cheW	-	-	NT	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	chemotaxis
MKNPMADF_02773	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
MKNPMADF_02774	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MKNPMADF_02775	0.0	addB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	exonuclease activity
MKNPMADF_02776	7.61e-81	-	-	-	-	-	-	-	-
MKNPMADF_02777	1.67e-141	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MKNPMADF_02778	1.5e-184	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKNPMADF_02779	1.23e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKNPMADF_02780	2.52e-205	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
MKNPMADF_02781	4.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MKNPMADF_02782	2.34e-211	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MKNPMADF_02783	4.62e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MKNPMADF_02784	5.83e-100	-	-	-	S	-	-	-	DinB family
MKNPMADF_02785	0.0	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
MKNPMADF_02786	2.21e-166	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MKNPMADF_02787	1.41e-264	-	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
MKNPMADF_02788	4.16e-150	ung2	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil DNA glycosylase superfamily
MKNPMADF_02790	1.88e-273	-	-	-	Q	-	-	-	COG1228 Imidazolonepropionase and related amidohydrolases
MKNPMADF_02791	2.47e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	SpoVT / AbrB like domain
MKNPMADF_02792	1.58e-59	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MKNPMADF_02793	5.37e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
MKNPMADF_02794	5.22e-65	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MKNPMADF_02795	0.0	cafA	-	-	J	ko:K08301	-	ko00000,ko01000,ko03009,ko03019	ribonuclease, Rne Rng family
MKNPMADF_02796	3.38e-172	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
MKNPMADF_02797	6.87e-163	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MKNPMADF_02798	1.93e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MKNPMADF_02799	9.17e-118	-	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MKNPMADF_02800	2.17e-97	-	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaC family
MKNPMADF_02801	6.33e-119	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
MKNPMADF_02802	6.84e-183	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
MKNPMADF_02803	3.82e-157	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKNPMADF_02804	1.48e-103	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
MKNPMADF_02805	2.41e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MKNPMADF_02806	1.99e-238	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
MKNPMADF_02807	2.9e-156	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
MKNPMADF_02808	1.66e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
MKNPMADF_02809	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
MKNPMADF_02810	3.61e-246	-	-	-	-	ko:K06380	-	ko00000	-
MKNPMADF_02811	1.82e-145	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MKNPMADF_02812	8.29e-293	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MKNPMADF_02813	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKNPMADF_02814	1.27e-37	-	-	-	-	-	-	-	-
MKNPMADF_02815	1.08e-139	-	-	-	-	-	-	-	-
MKNPMADF_02816	5.51e-239	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MKNPMADF_02817	2.7e-198	-	-	-	-	-	-	-	-
MKNPMADF_02818	7.35e-226	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
MKNPMADF_02819	3.38e-310	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
MKNPMADF_02820	3.02e-228	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
MKNPMADF_02821	2.87e-169	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MKNPMADF_02822	8.46e-212	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MKNPMADF_02823	5.2e-186	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
MKNPMADF_02824	3.42e-313	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MKNPMADF_02825	5.13e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MKNPMADF_02826	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MKNPMADF_02827	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
MKNPMADF_02828	2.85e-303	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKNPMADF_02829	8.96e-292	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKNPMADF_02830	4.97e-227	ysoA	-	-	O	-	-	-	COG0457 FOG TPR repeat
MKNPMADF_02831	4.07e-144	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKNPMADF_02832	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MKNPMADF_02833	1.12e-245	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MKNPMADF_02834	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MKNPMADF_02835	2.5e-235	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MKNPMADF_02836	3.55e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MKNPMADF_02837	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
MKNPMADF_02838	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
MKNPMADF_02839	1.35e-92	-	-	-	-	-	-	-	-
MKNPMADF_02840	0.0	-	-	-	M	-	-	-	Glycosyl transferase family group 2
MKNPMADF_02841	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
MKNPMADF_02842	1.2e-132	-	-	-	L	-	-	-	Integrase core domain
MKNPMADF_02843	2.83e-163	-	3.1.21.3	-	V	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
MKNPMADF_02844	1.15e-302	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
MKNPMADF_02845	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
MKNPMADF_02847	1.53e-14	-	-	-	-	-	-	-	-
MKNPMADF_02850	6.23e-123	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MKNPMADF_02851	5.31e-136	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKNPMADF_02852	1.89e-173	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MKNPMADF_02853	1.42e-236	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
MKNPMADF_02854	3.62e-248	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
MKNPMADF_02855	3.13e-42	-	-	-	C	-	-	-	4Fe-4S binding domain
MKNPMADF_02856	5.03e-191	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MKNPMADF_02857	1.34e-103	ysmB	-	-	K	-	-	-	transcriptional
MKNPMADF_02858	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKNPMADF_02859	2.33e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
MKNPMADF_02860	2.77e-45	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_02861	1.71e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
MKNPMADF_02862	1.2e-185	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MKNPMADF_02863	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
MKNPMADF_02864	5.12e-145	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
MKNPMADF_02865	7.08e-293	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
MKNPMADF_02866	7.17e-99	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MKNPMADF_02867	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKNPMADF_02868	1.37e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MKNPMADF_02869	4.22e-219	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
MKNPMADF_02870	3.49e-172	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
MKNPMADF_02871	3.35e-170	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MKNPMADF_02872	1.59e-131	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_02873	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKNPMADF_02874	4.19e-87	yshE	-	-	S	ko:K08989	-	ko00000	membrane
MKNPMADF_02875	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKNPMADF_02876	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
MKNPMADF_02877	8.3e-117	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
MKNPMADF_02878	4.31e-44	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKNPMADF_02879	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKNPMADF_02880	4.56e-244	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKNPMADF_02881	3.92e-164	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKNPMADF_02882	3.13e-42	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
MKNPMADF_02884	1.53e-24	-	-	-	-	-	-	-	-
MKNPMADF_02885	8.37e-257	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
MKNPMADF_02886	1.12e-85	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
MKNPMADF_02887	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKNPMADF_02888	9.32e-70	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
MKNPMADF_02889	5.42e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKNPMADF_02890	3.08e-39	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MKNPMADF_02891	2.34e-110	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKNPMADF_02892	3.18e-264	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
MKNPMADF_02893	2.79e-153	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_02894	1.29e-296	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKNPMADF_02895	2.55e-167	-	-	-	-	-	-	-	-
MKNPMADF_02896	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
MKNPMADF_02897	1.49e-224	-	-	-	C	-	-	-	Aldo/keto reductase family
MKNPMADF_02898	5.91e-234	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_02899	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKNPMADF_02900	6.73e-208	ytxC	-	-	S	-	-	-	YtxC-like family
MKNPMADF_02901	7.83e-285	mqnC	1.21.98.1	-	H	ko:K11784	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2)
MKNPMADF_02902	1.66e-217	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MKNPMADF_02903	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
MKNPMADF_02904	4.36e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKNPMADF_02905	1.6e-85	-	-	-	-	-	-	-	-
MKNPMADF_02906	1.05e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MKNPMADF_02907	6.76e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKNPMADF_02908	2.94e-128	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKNPMADF_02909	5.02e-134	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKNPMADF_02910	1.4e-197	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKNPMADF_02911	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKNPMADF_02912	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
MKNPMADF_02913	2.8e-170	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_02914	2.74e-96	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	helix_turn_helix ASNC type
MKNPMADF_02915	9.96e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
MKNPMADF_02916	3.09e-306	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
MKNPMADF_02917	5.73e-263	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKNPMADF_02918	4.98e-96	-	-	-	S	-	-	-	UPF0756 membrane protein
MKNPMADF_02919	4.09e-78	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
MKNPMADF_02920	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MKNPMADF_02921	3.27e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKNPMADF_02922	1.97e-228	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MKNPMADF_02923	1.1e-196	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKNPMADF_02924	2.38e-148	lutR_1	-	-	K	ko:K05799	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MKNPMADF_02925	4.23e-287	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
MKNPMADF_02926	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MKNPMADF_02927	4.62e-70	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
MKNPMADF_02928	1.03e-117	ytrI	-	-	-	-	-	-	-
MKNPMADF_02929	3.08e-213	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
MKNPMADF_02930	3.35e-11	ytpI	-	-	S	-	-	-	YtpI-like protein
MKNPMADF_02931	2.37e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
MKNPMADF_02933	3.84e-162	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
MKNPMADF_02934	2.05e-255	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
MKNPMADF_02935	4.51e-84	-	-	-	-	-	-	-	-
MKNPMADF_02936	4.14e-177	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_02938	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MKNPMADF_02939	1.18e-294	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKNPMADF_02941	1.03e-212	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	3'-5' exoribonuclease yhaM
MKNPMADF_02942	2.04e-275	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKNPMADF_02943	1.33e-228	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
MKNPMADF_02944	3.92e-110	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKNPMADF_02945	1.77e-250	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_02946	1.19e-97	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
MKNPMADF_02947	1.49e-154	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
MKNPMADF_02948	1.82e-126	yteJ	-	-	S	-	-	-	RDD family
MKNPMADF_02949	2.68e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
MKNPMADF_02950	7.95e-37	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MKNPMADF_02951	1.78e-283	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKNPMADF_02952	1.07e-262	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
MKNPMADF_02953	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKNPMADF_02954	2.54e-181	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MKNPMADF_02955	6.15e-146	yttP	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_02956	7.5e-19	-	-	-	L	ko:K07496	-	ko00000	Transposase
MKNPMADF_02957	1.88e-112	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MKNPMADF_02958	4.92e-142	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKNPMADF_02959	3.55e-297	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKNPMADF_02960	0.0	pbp1B	2.4.1.129	GT51	M	ko:K03693,ko:K12551	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	COG0744 Membrane carboxypeptidase (penicillin-binding protein)
MKNPMADF_02961	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKNPMADF_02962	2.34e-154	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MKNPMADF_02963	1.55e-142	acuB	-	-	S	ko:K04767	-	ko00000	Acetoin utilization protein AcuB
MKNPMADF_02964	2.28e-293	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
MKNPMADF_02965	5.04e-237	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MKNPMADF_02966	1.18e-251	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MKNPMADF_02967	1.14e-27	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
MKNPMADF_02968	1.68e-84	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKNPMADF_02969	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MKNPMADF_02970	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MKNPMADF_02971	6.41e-134	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKNPMADF_02972	5.66e-187	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
MKNPMADF_02973	1.15e-73	ytpP	-	-	CO	-	-	-	Thioredoxin
MKNPMADF_02974	1.06e-183	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MKNPMADF_02975	7.88e-100	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
MKNPMADF_02976	6.99e-112	yjjX	-	-	F	-	-	-	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MKNPMADF_02977	4.52e-262	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
MKNPMADF_02978	5.27e-64	ytzB	-	-	-	-	-	-	-
MKNPMADF_02979	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKNPMADF_02981	9.14e-197	ytmP	-	-	M	-	-	-	Phosphotransferase
MKNPMADF_02982	1.04e-209	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MKNPMADF_02983	4.58e-161	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_02984	7.62e-68	-	-	-	S	-	-	-	PFAM Uncharacterised protein family UPF0150
MKNPMADF_02985	1.65e-268	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKNPMADF_02986	6.01e-246	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MKNPMADF_02987	1.28e-224	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MKNPMADF_02988	6.62e-262	lpdA	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKNPMADF_02989	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
MKNPMADF_02990	1.19e-143	cidB	-	-	M	-	-	-	effector of murein hydrolase
MKNPMADF_02991	1.03e-77	-	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MKNPMADF_02992	2.67e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MKNPMADF_02993	9.53e-213	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MKNPMADF_02994	1.99e-205	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MKNPMADF_02995	7.71e-138	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_02996	3.45e-143	-	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
MKNPMADF_02997	6.52e-98	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MKNPMADF_02998	4.69e-43	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
MKNPMADF_02999	7.12e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MKNPMADF_03000	4.05e-266	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MKNPMADF_03001	9.29e-253	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MKNPMADF_03002	0.0	ytgP	-	-	S	ko:K03328,ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKNPMADF_03003	5.13e-209	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
MKNPMADF_03004	2.85e-89	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
MKNPMADF_03005	1.46e-287	yhaA1	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MKNPMADF_03006	1.31e-259	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
MKNPMADF_03007	2.95e-48	-	-	-	-	-	-	-	-
MKNPMADF_03008	1.12e-99	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MKNPMADF_03009	9.49e-169	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MKNPMADF_03010	1.3e-301	-	-	-	S	ko:K12941	-	ko00000,ko01002	amidohydrolase
MKNPMADF_03011	4.62e-103	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MKNPMADF_03012	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MKNPMADF_03013	2.07e-221	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MKNPMADF_03014	1.95e-244	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
MKNPMADF_03016	2.09e-131	ytqB	-	-	J	-	-	-	Putative rRNA methylase
MKNPMADF_03017	9.47e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
MKNPMADF_03018	1.3e-194	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
MKNPMADF_03019	3.24e-96	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MKNPMADF_03020	2.35e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKNPMADF_03021	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MKNPMADF_03023	3.06e-193	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MKNPMADF_03024	1.39e-230	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKNPMADF_03025	6.58e-175	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKNPMADF_03026	1.53e-175	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKNPMADF_03027	1.96e-108	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
MKNPMADF_03028	1.58e-284	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_03029	5.16e-110	ywpF	-	-	S	-	-	-	YwpF-like protein
MKNPMADF_03031	7.16e-280	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MKNPMADF_03032	1.2e-141	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
MKNPMADF_03033	1.52e-154	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
MKNPMADF_03034	2.62e-138	-	-	-	V	ko:K07448	-	ko00000,ko02048	Restriction endonuclease
MKNPMADF_03035	5.59e-223	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
MKNPMADF_03036	1.19e-192	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_03037	5.22e-197	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_03038	1.01e-206	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_03039	1.17e-128	pgpB3	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
MKNPMADF_03040	1.61e-296	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKNPMADF_03041	1.49e-97	-	-	-	S	-	-	-	Putative small multi-drug export protein
MKNPMADF_03042	2.82e-95	-	-	-	S	-	-	-	DinB superfamily
MKNPMADF_03043	1.34e-76	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
MKNPMADF_03044	1.42e-108	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
MKNPMADF_03045	3.16e-207	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MKNPMADF_03046	1.2e-211	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
MKNPMADF_03047	1.2e-48	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MKNPMADF_03049	2.25e-29	-	-	-	-	-	-	-	-
MKNPMADF_03050	5.95e-92	yugN	-	-	S	-	-	-	YugN-like family
MKNPMADF_03051	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MKNPMADF_03052	7.51e-262	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MKNPMADF_03053	1.16e-286	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
MKNPMADF_03054	2.41e-45	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
MKNPMADF_03055	7.86e-77	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
MKNPMADF_03056	3.03e-257	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
MKNPMADF_03057	4.96e-174	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKNPMADF_03058	3.31e-283	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
MKNPMADF_03059	4.23e-110	alaR	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03060	6.22e-107	-	-	-	L	-	-	-	Transposase IS200 like
MKNPMADF_03061	1.06e-110	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKNPMADF_03062	1.73e-182	-	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MKNPMADF_03063	1.81e-55	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKNPMADF_03064	5.33e-288	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
MKNPMADF_03065	5.93e-60	-	-	-	-	-	-	-	-
MKNPMADF_03066	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MKNPMADF_03067	1.5e-101	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
MKNPMADF_03068	1.84e-140	yuiC	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03069	2.61e-61	yuiB	-	-	S	-	-	-	Putative membrane protein
MKNPMADF_03070	1.27e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKNPMADF_03071	3.18e-237	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
MKNPMADF_03072	1.52e-262	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
MKNPMADF_03073	2.29e-92	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MKNPMADF_03074	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
MKNPMADF_03075	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
MKNPMADF_03076	1.34e-197	-	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MKNPMADF_03077	4.06e-140	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
MKNPMADF_03078	2.5e-79	yutM	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
MKNPMADF_03079	3.32e-13	-	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
MKNPMADF_03080	5.12e-267	mqnE	2.5.1.120	-	H	ko:K18285	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
MKNPMADF_03081	7.49e-206	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKNPMADF_03082	9.92e-57	-	-	-	-	-	-	-	-
MKNPMADF_03083	3.63e-54	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
MKNPMADF_03084	0.0	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MKNPMADF_03085	5.36e-68	yuzD	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03086	4.25e-49	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
MKNPMADF_03087	4.67e-202	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKNPMADF_03088	4.81e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MKNPMADF_03089	1.46e-304	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MKNPMADF_03090	3.55e-258	yutH	-	-	S	-	-	-	Spore coat protein
MKNPMADF_03091	1.37e-109	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
MKNPMADF_03092	4.77e-167	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKNPMADF_03093	1.78e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
MKNPMADF_03094	1.79e-59	-	-	-	-	-	-	-	-
MKNPMADF_03095	6.09e-67	yutD	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03096	4.63e-119	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MKNPMADF_03097	4.43e-222	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MKNPMADF_03098	9.51e-254	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
MKNPMADF_03099	0.0	-	-	-	C	ko:K18218	-	ko00000,ko00002,ko01504,ko02000	Na+/H+ antiporter family
MKNPMADF_03100	2.12e-177	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
MKNPMADF_03101	2.2e-115	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKNPMADF_03102	1.35e-198	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKNPMADF_03103	7.97e-65	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
MKNPMADF_03104	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
MKNPMADF_03105	6.45e-176	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MKNPMADF_03106	2.02e-214	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
MKNPMADF_03107	1.7e-84	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MKNPMADF_03108	1.26e-67	-	-	-	-	-	-	-	-
MKNPMADF_03109	7.58e-190	-	-	-	-	-	-	-	-
MKNPMADF_03111	1.03e-53	-	-	-	-	-	-	-	-
MKNPMADF_03112	8.46e-53	-	-	-	-	-	-	-	-
MKNPMADF_03113	1.86e-56	-	-	-	-	-	-	-	-
MKNPMADF_03114	2.05e-200	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MKNPMADF_03115	8.5e-55	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKNPMADF_03116	4.37e-45	-	-	-	S	-	-	-	Pathogenicity locus
MKNPMADF_03117	1.32e-102	-	-	-	H	-	-	-	RibD C-terminal domain
MKNPMADF_03118	3.03e-196	-	-	-	S	-	-	-	Phosphotransferase enzyme family
MKNPMADF_03119	7.66e-116	yvbU	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03120	3.81e-143	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	COG2814 Arabinose efflux permease
MKNPMADF_03121	5.74e-218	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MKNPMADF_03122	2.24e-174	msmR	-	-	K	-	-	-	AraC family transcriptional regulator
MKNPMADF_03123	2.71e-233	-	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo/keto reductase family
MKNPMADF_03124	3.43e-178	-	-	-	Q	-	-	-	Methyltransferase domain
MKNPMADF_03125	1.75e-270	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKNPMADF_03126	1.01e-298	bglH7	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
MKNPMADF_03127	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_03128	2.32e-154	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
MKNPMADF_03129	1.51e-23	-	-	-	S	-	-	-	YhfH-like protein
MKNPMADF_03130	2.73e-301	aceA	4.1.3.1	-	C	ko:K01637	ko00630,ko01100,ko01110,ko01120,ko01200,map00630,map01100,map01110,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Isocitrate lyase
MKNPMADF_03131	5.13e-117	-	-	-	T	-	-	-	Transcriptional regulator
MKNPMADF_03132	5.46e-195	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_03133	2.45e-98	nodB1	-	-	G	-	-	-	deacetylase
MKNPMADF_03134	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
MKNPMADF_03135	2.18e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
MKNPMADF_03136	1.44e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKNPMADF_03137	6.58e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
MKNPMADF_03138	8.04e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MKNPMADF_03139	4.09e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MKNPMADF_03140	2.26e-214	-	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MKNPMADF_03141	1.55e-122	-	-	-	S	-	-	-	Cobalamin adenosyltransferase
MKNPMADF_03142	1.39e-197	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
MKNPMADF_03143	8.61e-147	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MKNPMADF_03144	1.1e-234	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNPMADF_03145	6.74e-84	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MKNPMADF_03146	5.61e-82	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MKNPMADF_03147	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
MKNPMADF_03148	3.25e-269	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
MKNPMADF_03149	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
MKNPMADF_03150	2.87e-272	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKNPMADF_03151	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
MKNPMADF_03152	1.24e-157	-	-	-	S	-	-	-	Glycosyltransferase like family
MKNPMADF_03154	6.85e-07	-	-	-	-	-	-	-	-
MKNPMADF_03155	2.62e-139	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MKNPMADF_03156	6.5e-306	gabT	2.6.1.19	-	E	ko:K00823	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKNPMADF_03157	1.97e-310	-	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03158	3.31e-79	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNPMADF_03160	1.31e-103	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MKNPMADF_03161	1.27e-80	-	-	-	L	ko:K07496	-	ko00000	Transposase
MKNPMADF_03162	1e-78	-	-	-	S	ko:K15977	-	ko00000	DoxX
MKNPMADF_03163	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKNPMADF_03164	3.69e-179	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
MKNPMADF_03165	1.06e-176	-	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	COG1647 Esterase lipase
MKNPMADF_03166	1.23e-223	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_03167	1.94e-37	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
MKNPMADF_03168	3.2e-100	yclD	-	-	-	-	-	-	-
MKNPMADF_03169	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
MKNPMADF_03170	5.58e-93	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter TctB family
MKNPMADF_03171	6.75e-220	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MKNPMADF_03172	1.25e-282	-	4.2.1.158	-	M	ko:K20022	-	ko00000,ko01000	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain
MKNPMADF_03173	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_03174	1.72e-213	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MKNPMADF_03175	2.63e-149	-	-	-	K	-	-	-	FCD
MKNPMADF_03176	5.85e-33	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
MKNPMADF_03180	9.59e-305	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKNPMADF_03181	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
MKNPMADF_03182	3.78e-169	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKNPMADF_03183	5.42e-275	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MKNPMADF_03184	4.9e-239	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKNPMADF_03185	2.48e-229	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MKNPMADF_03186	8.73e-259	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKNPMADF_03188	3.02e-53	XAC3035	-	-	O	ko:K06191	-	ko00000	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MKNPMADF_03189	3.27e-295	sigL	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MKNPMADF_03191	6.73e-133	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKNPMADF_03192	1.73e-287	-	-	-	E	-	-	-	Peptidase dimerisation domain
MKNPMADF_03193	8.04e-72	-	-	-	S	ko:K09940	-	ko00000	Domain of unknown function (DUF4870)
MKNPMADF_03194	9.01e-272	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MKNPMADF_03195	2.12e-138	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKNPMADF_03196	3.91e-215	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKNPMADF_03197	2.76e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
MKNPMADF_03198	4.57e-51	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
MKNPMADF_03199	1.97e-228	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MKNPMADF_03200	3e-225	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MKNPMADF_03201	4.57e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MKNPMADF_03202	4.29e-116	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Nudix hydrolase
MKNPMADF_03203	8.31e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKNPMADF_03204	2.1e-247	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
MKNPMADF_03205	3.21e-306	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
MKNPMADF_03206	8.43e-157	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKNPMADF_03207	8.84e-138	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_03208	8.46e-161	-	-	-	K	-	-	-	FR47-like protein
MKNPMADF_03209	3.31e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
MKNPMADF_03210	5.18e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKNPMADF_03211	2.47e-164	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKNPMADF_03212	1.92e-147	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKNPMADF_03213	3.1e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
MKNPMADF_03214	8.59e-290	hisD	1.1.1.23, 1.1.1.308	-	E	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKNPMADF_03215	3.41e-144	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKNPMADF_03216	6.37e-278	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKNPMADF_03217	2.89e-105	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
MKNPMADF_03218	2.32e-151	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MKNPMADF_03219	5.6e-204	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
MKNPMADF_03220	5.06e-196	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKNPMADF_03221	2.18e-218	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKNPMADF_03222	2.08e-63	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
MKNPMADF_03223	7.33e-16	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MKNPMADF_03224	3.17e-201	yvlB	-	-	S	-	-	-	Putative adhesin
MKNPMADF_03225	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKNPMADF_03226	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKNPMADF_03227	3.73e-216	yoaV3	-	-	EG	-	-	-	EamA-like transporter family
MKNPMADF_03228	3.27e-258	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKNPMADF_03229	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
MKNPMADF_03230	3.6e-156	-	-	-	D	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	peptidase
MKNPMADF_03231	8.93e-194	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MKNPMADF_03232	3.53e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
MKNPMADF_03233	3.22e-189	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
MKNPMADF_03234	1.02e-232	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKNPMADF_03235	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKNPMADF_03236	6.07e-126	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKNPMADF_03237	4.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	cold-shock protein
MKNPMADF_03238	3.79e-189	-	-	-	-	-	-	-	-
MKNPMADF_03240	3.64e-86	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
MKNPMADF_03241	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MKNPMADF_03242	2.52e-63	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
MKNPMADF_03243	1.96e-45	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MKNPMADF_03244	7.62e-97	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MKNPMADF_03245	5.69e-238	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
MKNPMADF_03246	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
MKNPMADF_03247	2.18e-07	yvyG	-	-	NOU	-	-	-	Flagellar biosynthesis protein FlgN
MKNPMADF_03248	3.56e-52	-	-	-	N	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Anti-sigma-28 factor, FlgM
MKNPMADF_03249	1.28e-97	yvyF	-	-	S	-	-	-	flagellar protein
MKNPMADF_03250	5e-161	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
MKNPMADF_03251	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MKNPMADF_03252	3.68e-191	degV	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03253	4.63e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKNPMADF_03254	7.16e-257	degS	2.7.13.3	-	T	ko:K07683,ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MKNPMADF_03255	1.29e-147	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
MKNPMADF_03256	1.51e-131	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKNPMADF_03257	0.0	oppA1	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_03258	8.72e-203	oppC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	binding-protein-dependent transport systems inner membrane component
MKNPMADF_03259	4.99e-225	oppB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_03260	2.59e-190	oppF	-	-	P	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03261	1.47e-244	oppD	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03262	5.98e-105	-	-	-	K	ko:K03718	-	ko00000,ko03000	helix_turn_helix ASNC type
MKNPMADF_03263	7.86e-245	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03264	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MKNPMADF_03265	1.4e-206	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKNPMADF_03266	0.0	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKNPMADF_03267	0.0	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKNPMADF_03268	7.06e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
MKNPMADF_03269	1.81e-171	-	-	-	I	-	-	-	CDP-alcohol phosphatidyltransferase
MKNPMADF_03270	2.36e-292	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MKNPMADF_03271	0.0	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MKNPMADF_03272	5.17e-249	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKNPMADF_03273	2.25e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MKNPMADF_03274	4.03e-83	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
MKNPMADF_03275	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKNPMADF_03276	3.1e-246	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKNPMADF_03277	6.94e-146	ymaB	-	-	S	-	-	-	MutT family
MKNPMADF_03278	1.68e-126	pncA	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
MKNPMADF_03279	9.09e-34	-	-	-	-	-	-	-	-
MKNPMADF_03280	1.38e-277	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
MKNPMADF_03281	1.21e-165	fabG9	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_03282	0.0	cscA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKNPMADF_03283	0.0	-	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	invertase
MKNPMADF_03284	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03285	4.03e-207	lplC7	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
MKNPMADF_03286	4.79e-224	-	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
MKNPMADF_03287	3.84e-233	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	transcriptional
MKNPMADF_03288	2.83e-128	-	-	-	-	-	-	-	-
MKNPMADF_03289	9.03e-256	-	-	-	E	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_03290	3.42e-201	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03291	2.42e-206	-	-	-	G	ko:K02025,ko:K17238	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03292	2.98e-315	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03293	0.0	-	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MKNPMADF_03294	2.95e-29	-	-	-	K	-	-	-	sequence-specific DNA binding
MKNPMADF_03295	8.83e-69	-	-	-	K	-	-	-	sequence-specific DNA binding
MKNPMADF_03296	3.74e-204	-	-	-	S	-	-	-	NYN domain
MKNPMADF_03297	1.81e-155	-	-	-	-	-	-	-	-
MKNPMADF_03299	1.24e-81	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
MKNPMADF_03300	2.21e-157	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_03301	3.81e-168	-	-	-	-	-	-	-	-
MKNPMADF_03304	4.69e-28	-	-	-	K	ko:K07729,ko:K20388	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
MKNPMADF_03305	2.31e-141	-	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
MKNPMADF_03306	1.15e-179	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MKNPMADF_03307	2.08e-112	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03308	8.19e-143	yrzF	-	-	KLT	-	-	-	serine threonine protein kinase
MKNPMADF_03309	6.45e-12	-	-	-	-	-	-	-	-
MKNPMADF_03310	3.77e-52	-	-	-	-	-	-	-	-
MKNPMADF_03311	1.02e-260	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_03312	3.12e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKNPMADF_03314	1.77e-235	-	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKNPMADF_03315	1.67e-161	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNPMADF_03316	2.03e-130	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
MKNPMADF_03317	6.48e-202	yobV	-	-	K	-	-	-	WYL domain
MKNPMADF_03318	9.97e-114	dinB	-	-	S	-	-	-	DinB family
MKNPMADF_03319	1.83e-191	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
MKNPMADF_03320	7.91e-220	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKNPMADF_03321	4.24e-271	-	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_03323	5.72e-210	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MKNPMADF_03324	7.37e-138	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
MKNPMADF_03325	9.42e-122	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MKNPMADF_03326	2.28e-172	-	-	-	L	-	-	-	IstB-like ATP binding protein
MKNPMADF_03327	0.0	-	-	-	L	-	-	-	Transposase
MKNPMADF_03333	2.45e-248	-	-	-	UW	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
MKNPMADF_03338	1e-48	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_03339	1.4e-164	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_03340	1.49e-234	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MKNPMADF_03341	7.15e-178	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
MKNPMADF_03342	1.16e-88	-	-	-	-	-	-	-	-
MKNPMADF_03343	0.0	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKNPMADF_03344	3.84e-299	-	-	-	M	-	-	-	-O-antigen
MKNPMADF_03345	3.26e-70	-	-	-	-	-	-	-	-
MKNPMADF_03346	3.77e-248	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKNPMADF_03347	5.24e-188	-	-	-	S	-	-	-	Glycosyl transferase family 2
MKNPMADF_03348	0.0	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
MKNPMADF_03349	1.44e-146	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03350	9.49e-143	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Iron/manganese superoxide dismutases, C-terminal domain
MKNPMADF_03351	2.71e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1450)
MKNPMADF_03352	1.82e-41	-	-	-	C	-	-	-	4Fe-4S binding domain
MKNPMADF_03353	4.05e-88	-	-	-	S	ko:K09957	-	ko00000	Putative glycolipid-binding
MKNPMADF_03354	5.08e-300	-	-	-	S	ko:K12940	-	ko00000,ko01002	Peptidase dimerisation domain
MKNPMADF_03355	0.0	-	-	-	H	ko:K12942	-	ko00000	AbgT putative transporter family
MKNPMADF_03356	0.0	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	amidohydrolase
MKNPMADF_03357	2.86e-304	-	-	-	KT	-	-	-	transcriptional regulatory protein
MKNPMADF_03358	1.14e-185	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
MKNPMADF_03359	5.48e-261	thrCA	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Pyridoxal-phosphate dependent enzyme
MKNPMADF_03361	6.55e-109	-	-	-	M	ko:K01993	-	ko00000	PFAM secretion protein HlyD family protein
MKNPMADF_03362	7.4e-179	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
MKNPMADF_03363	2.5e-245	ybhR	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
MKNPMADF_03364	1e-147	ycfA	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03365	1.1e-84	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Chalcone and stilbene synthases, N-terminal domain
MKNPMADF_03366	1.26e-10	tlp	-	-	S	ko:K06434	-	ko00000	spore protein
MKNPMADF_03368	1.04e-110	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Phosphatidylglycerophosphatase A
MKNPMADF_03369	6.41e-100	-	-	-	-	-	-	-	-
MKNPMADF_03370	1.1e-196	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
MKNPMADF_03371	1.78e-97	fruD	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNPMADF_03372	0.0	fruC	2.7.1.202	-	G	ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_03373	3.47e-215	fruK-1	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
MKNPMADF_03374	2.19e-180	rpl	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
MKNPMADF_03375	1.91e-205	XK27_03180	-	-	T	-	-	-	Belongs to the universal stress protein A family
MKNPMADF_03377	3.99e-64	-	-	-	-	-	-	-	-
MKNPMADF_03378	1.73e-73	-	-	-	-	-	-	-	-
MKNPMADF_03379	3.66e-252	-	-	-	E	ko:K02055	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0687 Spermidine putrescine-binding periplasmic protein
MKNPMADF_03380	2.38e-222	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MKNPMADF_03381	8.85e-179	-	-	-	E	ko:K02054,ko:K11071	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1176 ABC-type spermidine putrescine transport system, permease component I
MKNPMADF_03382	3.46e-171	potC3	-	-	P	ko:K02053	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03383	2.11e-248	potA11	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKNPMADF_03384	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Adenine deaminase C-terminal domain
MKNPMADF_03385	0.0	M1-554	-	-	G	-	-	-	Endonuclease Exonuclease Phosphatase
MKNPMADF_03386	6.13e-19	-	-	-	S	-	-	-	Inner spore coat protein D
MKNPMADF_03387	9.91e-80	-	-	-	FJ	-	-	-	tRNA wobble adenosine to inosine editing
MKNPMADF_03388	1.51e-199	-	-	-	P	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_03389	5.44e-201	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03390	1.96e-291	-	-	-	G	-	-	-	ABC transporter substrate-binding protein
MKNPMADF_03391	9.11e-236	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKNPMADF_03392	0.0	ltaS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
MKNPMADF_03393	5.1e-163	lacR	-	-	K	ko:K02530	-	ko00000,ko03000	DeoR C terminal sensor domain
MKNPMADF_03394	3.18e-282	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKNPMADF_03395	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MKNPMADF_03396	0.0	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKNPMADF_03397	1.16e-213	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MKNPMADF_03399	0.0	mdr	-	-	EGP	-	-	-	the major facilitator superfamily
MKNPMADF_03400	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
MKNPMADF_03401	2.25e-209	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
MKNPMADF_03402	4.37e-65	-	-	-	-	-	-	-	-
MKNPMADF_03403	1.06e-30	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	Capsular polysaccharide biosynthesis protein
MKNPMADF_03404	2.8e-168	yvcP	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_03405	5.13e-244	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
MKNPMADF_03406	9e-181	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_03407	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
MKNPMADF_03409	0.0	-	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MKNPMADF_03410	7.66e-196	-	-	-	S	-	-	-	CAAX amino terminal protease family protein
MKNPMADF_03411	7.12e-207	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase (reverse transcriptase)
MKNPMADF_03412	8.18e-215	-	-	-	K	-	-	-	Putative sugar-binding domain
MKNPMADF_03413	1.1e-78	-	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
MKNPMADF_03414	3.4e-231	-	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol sorbitol-specific transporter subunit IIB
MKNPMADF_03415	3.57e-114	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
MKNPMADF_03416	1.83e-87	-	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
MKNPMADF_03417	1.24e-299	-	-	-	E	-	-	-	SAF
MKNPMADF_03418	2.31e-48	-	-	-	G	-	-	-	PTS HPr component phosphorylation site
MKNPMADF_03419	3.19e-148	-	-	-	-	-	-	-	-
MKNPMADF_03420	5.53e-119	-	-	-	S	-	-	-	VanZ like family
MKNPMADF_03421	2.74e-101	yybA	-	-	K	-	-	-	transcriptional
MKNPMADF_03422	7.8e-119	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_03423	8.21e-220	ssuA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKNPMADF_03424	1.01e-133	ssuC_2	-	-	P	ko:K02050,ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03425	1.63e-198	ssuB	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKNPMADF_03426	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MKNPMADF_03427	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MKNPMADF_03428	8.71e-258	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
MKNPMADF_03429	3.65e-291	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
MKNPMADF_03430	6.23e-180	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKNPMADF_03431	1.96e-226	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MKNPMADF_03432	1.57e-14	-	-	-	Q	ko:K02614	ko00360,map00360	ko00000,ko00001,ko01000	Thioesterase superfamily
MKNPMADF_03433	1.3e-14	mazE	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
MKNPMADF_03434	1.07e-52	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKNPMADF_03435	4.47e-31	topA2	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Topoisomerase IA
MKNPMADF_03437	0.0	-	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MKNPMADF_03438	8.74e-67	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_03439	3.56e-141	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
MKNPMADF_03440	7.87e-111	-	-	-	-	-	-	-	-
MKNPMADF_03441	3.69e-187	M1-276	-	-	-	-	-	-	-
MKNPMADF_03442	1.94e-268	ysh1	-	-	J	-	-	-	Metallo-beta-lactamase superfamily
MKNPMADF_03443	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03444	4.56e-243	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03445	2.81e-233	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MKNPMADF_03446	3.92e-206	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03447	7.53e-73	-	-	-	S	-	-	-	Family of unknown function (DUF5367)
MKNPMADF_03448	1.52e-129	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_03450	2.68e-200	-	-	-	EG	-	-	-	EamA-like transporter family
MKNPMADF_03451	2.79e-313	ywoF	-	-	P	-	-	-	Right handed beta helix region
MKNPMADF_03452	3.71e-122	mutT	3.6.1.13, 3.6.1.55	-	L	ko:K01515,ko:K03574	ko00230,map00230	ko00000,ko00001,ko01000,ko03400	nUDIX hydrolase
MKNPMADF_03453	1.43e-81	-	-	-	S	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNPMADF_03454	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
MKNPMADF_03455	1.43e-188	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03456	8.08e-206	-	-	-	G	-	-	-	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03457	1.75e-267	-	3.2.1.180	GH88	O	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MKNPMADF_03458	8.52e-212	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_03459	1.46e-284	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_03460	1.93e-266	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_03461	4.83e-129	-	-	-	K	-	-	-	AraC-like ligand binding domain
MKNPMADF_03462	4.49e-182	inoDHR	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_03463	4.18e-200	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03464	2.28e-219	ugpA7	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03465	0.0	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein
MKNPMADF_03466	2.45e-268	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_03467	1.76e-177	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
MKNPMADF_03468	1.54e-217	-	-	-	K	-	-	-	Cupin domain
MKNPMADF_03469	1.46e-240	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_03470	1.07e-77	-	-	-	S	-	-	-	Protein of unknown function, DUF393
MKNPMADF_03471	2.74e-189	yfhB	-	-	S	-	-	-	PhzF family
MKNPMADF_03472	1.35e-132	-	-	-	V	-	-	-	Beta-lactamase
MKNPMADF_03473	5.59e-116	plsY1	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKNPMADF_03474	0.0	-	-	-	E	-	-	-	Aminotransferase class-V
MKNPMADF_03475	0.0	-	-	-	M	-	-	-	Sulfatase
MKNPMADF_03476	1.67e-86	-	-	-	E	ko:K07032	-	ko00000	lactoylglutathione lyase activity
MKNPMADF_03477	9.73e-193	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MKNPMADF_03478	2.07e-139	-	-	-	K	-	-	-	LysR substrate binding domain
MKNPMADF_03479	3.01e-156	-	-	-	S	-	-	-	Sulfatase-modifying factor enzyme 1
MKNPMADF_03480	2.42e-130	-	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Putative N-acetylmannosamine-6-phosphate epimerase
MKNPMADF_03481	2.48e-60	ptbA	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, glucose subfamily, IIA
MKNPMADF_03482	1.72e-259	-	-	-	P	-	-	-	Sulfatase
MKNPMADF_03483	9.08e-294	ptsG	2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02778,ko:K02779,ko:K02790,ko:K02791	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
MKNPMADF_03484	2.17e-112	-	-	-	K	ko:K11922	-	ko00000,ko03000	Regulates the succiny-lCoA synthetase operon
MKNPMADF_03485	1.42e-103	-	-	-	S	ko:K07090	-	ko00000	Sulfite exporter TauE/SafE
MKNPMADF_03486	3.26e-200	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MKNPMADF_03487	1.34e-40	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
MKNPMADF_03488	3.03e-190	araQ	-	-	P	ko:K10190,ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_03489	9.42e-203	-	-	-	G	ko:K10189	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03490	3.91e-305	-	-	-	G	ko:K10188	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_03491	3.06e-64	-	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MKNPMADF_03492	4.95e-150	-	-	-	E	-	-	-	AzlC protein
MKNPMADF_03493	1.19e-122	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_03494	3.21e-210	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	RNA-directed DNA polymerase (reverse transcriptase)
MKNPMADF_03495	2.48e-49	M1-753	-	-	M	-	-	-	FR47-like protein
MKNPMADF_03497	2.15e-48	ydaS	-	-	S	-	-	-	membrane
MKNPMADF_03498	1.8e-117	ywmF	-	-	S	-	-	-	Peptidase M50
MKNPMADF_03499	1.24e-298	-	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MKNPMADF_03500	1.9e-147	ypgQ	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
MKNPMADF_03501	3.9e-35	-	-	-	-	-	-	-	-
MKNPMADF_03502	0.0	apc3	-	-	EQ	-	-	-	Hydantoinase/oxoprolinase
MKNPMADF_03503	1.2e-260	-	-	-	S	ko:K09703	-	ko00000	Protein of unknown function (DUF917)
MKNPMADF_03504	1.73e-275	-	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
MKNPMADF_03505	4.17e-133	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_03506	7.52e-173	-	-	-	K	-	-	-	acetyltransferase
MKNPMADF_03507	4.68e-104	-	-	-	S	ko:K06385	-	ko00000	Stage II sporulation protein P (SpoIIP)
MKNPMADF_03508	1.29e-198	-	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein kinase domain
MKNPMADF_03509	5.62e-75	-	-	-	FG	ko:K02503	-	ko00000,ko04147	HIT domain
MKNPMADF_03510	6.57e-209	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNPMADF_03511	1.81e-57	-	-	-	S	ko:K06361,ko:K06365,ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Histidine kinase
MKNPMADF_03512	1.56e-114	-	-	-	-	-	-	-	-
MKNPMADF_03514	1.62e-228	-	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
MKNPMADF_03515	4.31e-296	-	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03516	0.0	-	3.5.4.28, 3.5.4.31	-	F	ko:K12960	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MKNPMADF_03517	2.11e-292	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKNPMADF_03518	3.32e-305	hutI	3.5.2.7	-	Q	ko:K01468	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Imidazolone-5-propionate hydrolase
MKNPMADF_03519	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MKNPMADF_03520	0.0	-	-	-	T	-	-	-	COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MKNPMADF_03521	1.12e-271	-	-	-	G	-	-	-	Transmembrane secretion effector
MKNPMADF_03522	3.24e-245	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_03523	1.57e-134	desR	-	-	K	ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
MKNPMADF_03524	5.63e-145	-	-	-	-	-	-	-	-
MKNPMADF_03525	1.76e-196	-	-	-	K	ko:K03488	-	ko00000,ko03000	antiterminator
MKNPMADF_03526	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MKNPMADF_03527	8.62e-223	-	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
MKNPMADF_03528	8.54e-123	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
MKNPMADF_03529	4.35e-61	-	-	-	-	-	-	-	-
MKNPMADF_03530	0.000204	-	-	-	S	-	-	-	Pfam Methyltransferase
MKNPMADF_03531	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
MKNPMADF_03532	2.15e-262	gatD	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
MKNPMADF_03533	2.33e-29	-	-	-	-	-	-	-	-
MKNPMADF_03534	6.2e-241	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKNPMADF_03535	8.53e-287	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
MKNPMADF_03536	8.66e-56	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_03537	5.29e-100	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNPMADF_03538	0.0	-	-	-	GKT	-	-	-	COG3711 Transcriptional antiterminator
MKNPMADF_03539	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
MKNPMADF_03540	4.02e-239	-	-	-	-	-	-	-	-
MKNPMADF_03541	6.07e-133	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
MKNPMADF_03542	7.32e-220	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
MKNPMADF_03543	2.94e-141	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MKNPMADF_03544	2.83e-249	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
MKNPMADF_03545	1.37e-117	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MKNPMADF_03546	6.4e-258	siaT_3	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MKNPMADF_03547	3.92e-110	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_03548	1.22e-227	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
MKNPMADF_03549	6.34e-230	regR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
MKNPMADF_03550	1.4e-69	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator PadR-like family
MKNPMADF_03551	4.46e-94	-	-	-	-	-	-	-	-
MKNPMADF_03552	9.73e-98	-	-	-	-	-	-	-	-
MKNPMADF_03553	1.79e-76	-	-	-	EGP	-	-	-	Major facilitator superfamily
MKNPMADF_03554	9.36e-71	-	-	-	S	-	-	-	PFAM Glycosyl transferase family 2
MKNPMADF_03555	1.23e-07	-	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
MKNPMADF_03556	4.95e-70	-	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	TIGRFAM glutamine amidotransferase of anthranilate synthase
MKNPMADF_03557	3.78e-107	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MKNPMADF_03558	1.47e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase, Mutator family
MKNPMADF_03560	5.19e-251	ysdC_3	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	M42 glutamyl aminopeptidase
MKNPMADF_03561	6.91e-55	M1-485	-	-	S	-	-	-	Membrane
MKNPMADF_03562	6.94e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
MKNPMADF_03563	2.24e-227	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKNPMADF_03564	7.71e-186	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
MKNPMADF_03565	2.53e-170	-	-	-	S	ko:K06976	-	ko00000	GNAT acetyltransferase
MKNPMADF_03566	0.0	-	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
MKNPMADF_03567	0.0	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
MKNPMADF_03568	6.58e-34	-	-	-	-	-	-	-	-
MKNPMADF_03569	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
MKNPMADF_03570	1.02e-42	-	-	-	-	-	-	-	-
MKNPMADF_03571	1.76e-160	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_03572	1.61e-165	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	ABC transporter permease
MKNPMADF_03573	5.86e-220	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03574	4.36e-178	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
MKNPMADF_03575	1.26e-166	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
MKNPMADF_03576	1.73e-141	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
MKNPMADF_03577	7.73e-139	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MKNPMADF_03578	6.56e-233	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_03579	1.22e-159	yvqF	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
MKNPMADF_03580	8.85e-131	-	-	-	-	-	-	-	-
MKNPMADF_03581	3.99e-07	liaI	-	-	-	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	-
MKNPMADF_03582	7.91e-147	-	-	-	S	-	-	-	Cupin
MKNPMADF_03583	0.0	-	-	-	M	-	-	-	glycoside hydrolase family 81
MKNPMADF_03584	2.44e-243	cytR	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKNPMADF_03585	3e-185	-	-	-	P	ko:K10242	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_03586	1.32e-200	araP	-	-	P	ko:K10189,ko:K10241,ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM binding-protein-dependent transport systems inner membrane component
MKNPMADF_03587	9.73e-252	-	-	-	G	ko:K10240	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PFAM extracellular solute-binding protein family 1
MKNPMADF_03588	1.54e-155	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MKNPMADF_03589	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKNPMADF_03590	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKNPMADF_03591	2.86e-215	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_03592	9.9e-216	-	-	-	K	-	-	-	WYL domain
MKNPMADF_03593	2.33e-143	-	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKNPMADF_03594	6.84e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKNPMADF_03595	1.03e-194	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
MKNPMADF_03596	4.85e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
MKNPMADF_03597	5.09e-208	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_03598	0.0	gdhA	1.4.1.2, 1.4.1.4	-	E	ko:K00260,ko:K00262	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
MKNPMADF_03599	4.44e-175	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKNPMADF_03600	7.25e-215	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_03601	1.73e-254	-	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
MKNPMADF_03602	1.17e-170	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MKNPMADF_03603	2.42e-72	-	-	-	S	-	-	-	Dinitrogenase iron-molybdenum cofactor
MKNPMADF_03604	1.09e-308	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_03605	7.82e-107	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
MKNPMADF_03606	4e-204	ytlI3	-	-	K	ko:K21960	-	ko00000,ko03000	LysR substrate binding domain
MKNPMADF_03607	3.46e-112	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MKNPMADF_03608	4.47e-155	-	-	-	S	-	-	-	membrane
MKNPMADF_03609	1.03e-37	-	-	-	S	-	-	-	spore protein
MKNPMADF_03610	8.83e-39	-	-	-	S	ko:K06418,ko:K06419	-	ko00000	spore protein
MKNPMADF_03611	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MKNPMADF_03613	4.62e-194	yerO	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03614	1.22e-159	-	-	-	-	-	-	-	-
MKNPMADF_03615	1.25e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
MKNPMADF_03616	8.89e-80	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
MKNPMADF_03617	2.07e-141	-	-	-	Q	-	-	-	Methyltransferase domain
MKNPMADF_03618	5.9e-180	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
MKNPMADF_03619	2.54e-10	-	-	-	-	-	-	-	-
MKNPMADF_03620	4.68e-282	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKNPMADF_03621	5.8e-215	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
MKNPMADF_03622	9.69e-222	-	-	-	P	ko:K07217	-	ko00000	Catalase
MKNPMADF_03623	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2254)
MKNPMADF_03624	5.28e-202	-	-	-	E	ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Glycine betaine ABC transporter
MKNPMADF_03625	3.92e-305	-	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
MKNPMADF_03626	7.1e-176	srtB	3.4.22.70	-	S	ko:K08600	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MKNPMADF_03627	7.05e-172	fepC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_03628	1.64e-217	fhuB11	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_03629	1.88e-199	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_03630	0.0	-	-	-	M	-	-	-	Cell surface protein
MKNPMADF_03631	1.25e-143	isdC	-	-	M	-	-	-	NEAr Transporter domain
MKNPMADF_03632	4.89e-70	isdG	1.14.99.48	-	C	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the biliverdin in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron
MKNPMADF_03633	1.36e-220	fhuG7	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_03634	3.73e-213	fhuD11	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MKNPMADF_03635	7.74e-280	adhB	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MKNPMADF_03636	2.09e-171	-	-	-	S	-	-	-	Methyltransferase domain
MKNPMADF_03637	1.7e-141	-	-	-	K	-	-	-	Bacterial transcriptional repressor C-terminal
MKNPMADF_03638	0.0	-	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
MKNPMADF_03639	1.13e-277	-	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
MKNPMADF_03640	6.85e-159	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MKNPMADF_03641	4.31e-194	gltR3	-	-	K	-	-	-	LysR substrate binding domain
MKNPMADF_03642	4.61e-221	-	3.8.1.3	-	S	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
MKNPMADF_03643	9e-191	-	5.1.3.22	-	G	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Xylose isomerase-like TIM barrel
MKNPMADF_03644	3.57e-236	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
MKNPMADF_03645	6.92e-236	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_03646	7.46e-188	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03647	2.45e-217	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03648	1.16e-304	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03649	9.3e-275	-	-	-	GK	-	-	-	ROK family
MKNPMADF_03650	3.56e-279	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MKNPMADF_03651	7.19e-83	yqiX	-	-	S	-	-	-	YolD-like protein
MKNPMADF_03653	3.02e-06	sda	-	-	S	ko:K06371	-	ko00000	sporulation
MKNPMADF_03654	1.87e-121	-	-	-	K	-	-	-	Mga helix-turn-helix domain
MKNPMADF_03655	1.61e-209	-	-	-	K	-	-	-	Mga helix-turn-helix domain
MKNPMADF_03656	2.17e-62	-	-	-	-	-	-	-	-
MKNPMADF_03657	9.92e-110	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
MKNPMADF_03658	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MKNPMADF_03659	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase
MKNPMADF_03660	8.44e-248	dctP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKNPMADF_03661	0.0	-	-	-	-	-	-	-	-
MKNPMADF_03662	5.6e-210	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
MKNPMADF_03663	7.09e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKNPMADF_03664	1.25e-150	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
MKNPMADF_03666	2.96e-208	-	-	-	V	-	-	-	VanW like protein
MKNPMADF_03667	2.4e-118	-	-	-	V	-	-	-	(ABC) transporter
MKNPMADF_03668	7.19e-58	-	-	-	K	ko:K10947	-	ko00000,ko03000	PadR family transcriptional regulator
MKNPMADF_03669	1.41e-144	yqeB	-	-	-	-	-	-	-
MKNPMADF_03670	2.16e-130	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MKNPMADF_03671	3.54e-193	yojH	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MKNPMADF_03672	0.0	-	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKNPMADF_03673	1.52e-114	-	1.8.5.2	-	S	ko:K16937	ko00920,ko01120,map00920,map01120	ko00000,ko00001,ko01000	DoxX
MKNPMADF_03674	4.27e-33	-	-	-	-	-	-	-	-
MKNPMADF_03675	6.6e-79	-	-	-	-	-	-	-	-
MKNPMADF_03676	3.09e-141	-	-	-	K	ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MKNPMADF_03678	3.93e-199	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MKNPMADF_03679	7.29e-245	-	-	-	G	-	-	-	Xylose isomerase
MKNPMADF_03680	1.03e-179	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03681	3.21e-216	-	-	-	P	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03682	1.12e-285	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03683	5.89e-231	-	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
MKNPMADF_03684	1.4e-235	-	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MKNPMADF_03685	2.74e-129	-	-	-	L	ko:K07482	-	ko00000	Integrase
MKNPMADF_03686	2.78e-73	-	-	-	S	-	-	-	Ketosteroid isomerase-related protein
MKNPMADF_03687	1.1e-182	-	-	-	K	-	-	-	Helix-turn-helix domain
MKNPMADF_03688	2.25e-216	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MKNPMADF_03689	1.02e-195	dkgB	-	-	S	-	-	-	Aldo/keto reductase family
MKNPMADF_03690	3.68e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKNPMADF_03691	8.22e-292	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
MKNPMADF_03692	6.94e-169	-	-	-	S	-	-	-	Nucleotidyltransferase domain
MKNPMADF_03693	2.23e-196	-	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
MKNPMADF_03694	1.32e-153	-	-	-	KT	-	-	-	Forkhead associated domain
MKNPMADF_03695	1.04e-305	amaB_2	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKNPMADF_03696	3.31e-195	yuiI	-	-	S	ko:K07017	-	ko00000	Putative esterase
MKNPMADF_03697	2.8e-232	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_03698	7.05e-227	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_03699	3.61e-220	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
MKNPMADF_03700	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
MKNPMADF_03701	3.57e-101	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03702	1.31e-161	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
MKNPMADF_03703	7.82e-59	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_03704	3.32e-225	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MKNPMADF_03705	8.34e-228	ectD	1.14.11.55	-	Q	ko:K10674	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Phytanoyl-CoA dioxygenase (PhyH)
MKNPMADF_03706	2.31e-219	-	-	-	-	-	-	-	-
MKNPMADF_03707	3.67e-299	gerKA	-	-	EG	ko:K06295	-	ko00000	Spore germination protein
MKNPMADF_03708	3.55e-225	gerKB	-	-	E	-	-	-	Spore germination protein
MKNPMADF_03709	1.97e-239	gerKC	-	-	S	-	-	-	Spore germination B3/ GerAC like, C-terminal
MKNPMADF_03710	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
MKNPMADF_03711	1.38e-171	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_03712	0.0	-	-	-	S	-	-	-	Chlorophyllase enzyme
MKNPMADF_03713	4.32e-80	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNPMADF_03714	0.0	-	-	-	GKT	-	-	-	Mga helix-turn-helix domain
MKNPMADF_03715	6.64e-216	-	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKNPMADF_03716	1.07e-58	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
MKNPMADF_03717	1.35e-268	-	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
MKNPMADF_03718	1.32e-190	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MKNPMADF_03720	7.41e-131	-	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MKNPMADF_03721	1.33e-06	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
MKNPMADF_03722	1.24e-198	-	2.1.1.184	-	J	ko:K00561	-	br01600,ko00000,ko01000,ko01504,ko03009	Ribosomal RNA adenine dimethylases
MKNPMADF_03724	4.02e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4260)
MKNPMADF_03725	3.12e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_03726	2.67e-250	-	6.3.5.5	-	S	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	ATP-grasp domain
MKNPMADF_03727	8.73e-261	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Peptidase dimerisation domain
MKNPMADF_03728	1.29e-118	-	-	-	S	-	-	-	DinB superfamily
MKNPMADF_03730	6.62e-163	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKNPMADF_03731	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
MKNPMADF_03732	1.09e-293	yvfO	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
MKNPMADF_03733	6.25e-185	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MKNPMADF_03734	5.38e-308	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MKNPMADF_03735	3.17e-298	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MKNPMADF_03736	2.06e-233	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_03737	0.0	-	-	-	-	-	-	-	-
MKNPMADF_03738	0.0	-	-	-	-	-	-	-	-
MKNPMADF_03739	2.37e-123	-	-	-	-	-	-	-	-
MKNPMADF_03741	4.62e-193	yxxF	-	-	EG	-	-	-	EamA-like transporter family
MKNPMADF_03742	1.39e-189	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03743	0.0	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Fibronectin type III-like domain
MKNPMADF_03744	2.35e-188	XK27_01805	-	-	M	-	-	-	Glycosyltransferase like family 2
MKNPMADF_03745	5.23e-117	-	-	-	-	-	-	-	-
MKNPMADF_03746	0.0	-	3.2.1.21, 3.2.1.52	GH3	G	ko:K01207,ko:K05349	ko00460,ko00500,ko00520,ko00531,ko00940,ko01100,ko01110,ko01501,map00460,map00500,map00520,map00531,map00940,map01100,map01110,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
MKNPMADF_03747	0.0	-	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 3 family
MKNPMADF_03748	8.15e-145	gltC_1	-	-	K	-	-	-	DNA-binding transcription factor activity
MKNPMADF_03749	6.87e-226	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MKNPMADF_03750	4.65e-129	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKNPMADF_03751	3.01e-192	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_03752	1.68e-228	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_03753	6.8e-233	-	-	-	E	-	-	-	Amidinotransferase
MKNPMADF_03754	0.0	-	-	-	E	-	-	-	Sodium:solute symporter family
MKNPMADF_03755	5.19e-170	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_03756	2.99e-239	-	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKNPMADF_03757	2.08e-265	-	-	-	S	-	-	-	Erythromycin esterase
MKNPMADF_03758	7.91e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_03759	1.82e-217	-	-	-	S	-	-	-	Choline/ethanolamine kinase
MKNPMADF_03760	1.69e-71	-	-	-	-	-	-	-	-
MKNPMADF_03761	0.0	-	-	-	-	-	-	-	-
MKNPMADF_03762	7.46e-120	-	-	-	-	-	-	-	-
MKNPMADF_03763	8.58e-85	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03764	7.49e-95	-	-	-	-	-	-	-	-
MKNPMADF_03767	1.9e-113	-	-	-	-	-	-	-	-
MKNPMADF_03768	8.02e-222	-	-	-	-	-	-	-	-
MKNPMADF_03769	6.55e-149	-	-	-	-	-	-	-	-
MKNPMADF_03770	1.14e-205	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
MKNPMADF_03771	1.33e-205	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MKNPMADF_03772	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MKNPMADF_03773	5.42e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MKNPMADF_03774	9.82e-202	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKNPMADF_03775	6.36e-231	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
MKNPMADF_03776	8.99e-226	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
MKNPMADF_03778	1.8e-222	-	-	-	L	ko:K07496	-	ko00000	Transposase
MKNPMADF_03779	4.74e-47	suhB	3.1.3.25, 3.1.3.7	-	G	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	ko00000,ko00001,ko00002,ko01000,ko03016	inositol monophosphate 1-phosphatase activity
MKNPMADF_03780	5.52e-129	-	-	-	L	-	-	-	Domain of unknown function (DUF4357)
MKNPMADF_03781	2.39e-106	-	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Helix-hairpin-helix motif
MKNPMADF_03783	1.27e-58	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
MKNPMADF_03784	0.0	-	2.7.13.3	-	T	ko:K20487	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKNPMADF_03785	1.24e-156	-	-	-	T	-	-	-	Transcriptional regulatory protein, C terminal
MKNPMADF_03786	1.51e-161	-	-	-	-	-	-	-	-
MKNPMADF_03787	3.04e-159	-	-	-	S	-	-	-	ABC-2 family transporter protein
MKNPMADF_03788	8.87e-158	pstB13	-	-	V	-	-	-	AAA domain, putative AbiEii toxin, Type IV TA system
MKNPMADF_03789	3.1e-131	-	-	-	H	-	-	-	Flavoprotein
MKNPMADF_03790	0.0	spaC1	-	-	V	ko:K20484	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lanthionine synthetase C-like protein
MKNPMADF_03791	0.0	bsaB	-	-	S	ko:K20483	ko02020,ko02024,map02020,map02024	ko00000,ko00001	Lantibiotic dehydratase, C terminus
MKNPMADF_03792	2.63e-209	XK27_06795	-	-	K	ko:K20391	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
MKNPMADF_03793	0.0	yvcC1	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
MKNPMADF_03795	5.23e-171	-	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MKNPMADF_03796	3.01e-192	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03797	4e-180	-	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03798	2.07e-170	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MKNPMADF_03799	4.56e-181	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03800	1.2e-311	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKNPMADF_03802	6.04e-71	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MKNPMADF_03803	1.12e-127	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
MKNPMADF_03804	0.0	-	-	-	M	-	-	-	cell wall anchor domain
MKNPMADF_03805	3.74e-98	-	-	-	T	-	-	-	Bacterial transcriptional activator domain
MKNPMADF_03806	1.45e-256	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_03808	5.15e-229	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_03809	4.04e-252	rspA	4.2.1.8	-	M	ko:K08323	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
MKNPMADF_03810	1.1e-115	-	-	-	K	-	-	-	Helix-turn-helix domain
MKNPMADF_03811	2.13e-26	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKNPMADF_03814	7.52e-176	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
MKNPMADF_03815	1.23e-39	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_03816	6.31e-78	yoaS	-	-	S	-	-	-	membrane
MKNPMADF_03817	7.13e-132	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
MKNPMADF_03818	3.17e-71	yyaQ	-	-	S	-	-	-	Protein conserved in bacteria
MKNPMADF_03819	6.9e-200	kbaY	4.1.2.13, 4.1.2.40	-	G	ko:K01624,ko:K08302	ko00010,ko00030,ko00051,ko00052,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00052,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway
MKNPMADF_03820	8.15e-242	-	1.1.1.14, 1.1.1.251	-	C	ko:K00008,ko:K00094	ko00040,ko00051,ko00052,ko01100,map00040,map00051,map00052,map01100	ko00000,ko00001,ko00002,ko01000	Alcohol dehydrogenase GroES-like domain
MKNPMADF_03821	2.91e-311	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3775 Phosphotransferase system, galactitol-specific IIC component
MKNPMADF_03822	2.76e-55	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG3414 Phosphotransferase system, galactitol-specific IIB component
MKNPMADF_03823	1.32e-101	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNPMADF_03824	9.72e-182	-	-	-	K	ko:K02530	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
MKNPMADF_03825	2.98e-218	lacC	2.7.1.144	-	G	ko:K00917	ko00052,ko01100,map00052,map01100	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
MKNPMADF_03826	3.58e-87	yqjY	-	-	K	ko:K06977	-	ko00000	Acetyltransferase (GNAT) domain
MKNPMADF_03827	6.41e-126	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
MKNPMADF_03828	5.49e-48	-	-	-	L	ko:K07483	-	ko00000	Transposase
MKNPMADF_03829	1.73e-108	-	-	-	S	-	-	-	Protein of unknown function with HXXEE motif
MKNPMADF_03831	1.12e-94	-	-	-	-	-	-	-	-
MKNPMADF_03832	5.63e-176	glvR	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
MKNPMADF_03833	0.0	malP	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_03834	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKNPMADF_03835	1.33e-125	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
MKNPMADF_03836	0.0	-	-	-	C	-	-	-	FAD dependent oxidoreductase
MKNPMADF_03837	5.43e-191	ugpE3	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03838	1.66e-217	-	-	-	U	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03839	4.99e-312	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03840	0.0	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_03841	1.5e-174	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKNPMADF_03842	0.0	-	-	-	G	-	-	-	beta-fructofuranosidase activity
MKNPMADF_03844	5.46e-111	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MKNPMADF_03845	7.66e-166	-	-	-	S	-	-	-	CRISPR-associated endoribonuclease Cas6
MKNPMADF_03846	1.62e-132	-	-	-	-	-	-	-	-
MKNPMADF_03847	1.17e-188	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKNPMADF_03848	1.17e-141	-	-	-	L	-	-	-	RAMP superfamily
MKNPMADF_03849	0.0	-	-	-	S	-	-	-	Psort location Cytoplasmic, score 8.87
MKNPMADF_03850	1.04e-158	-	-	-	-	-	-	-	-
MKNPMADF_03852	0.0	-	-	-	M	-	-	-	Belongs to the BCCT transporter (TC 2.A.15) family
MKNPMADF_03854	5.23e-102	-	-	-	S	-	-	-	yiaA/B two helix domain
MKNPMADF_03855	0.0	-	-	-	M	-	-	-	Glycosyl hydrolase family 59
MKNPMADF_03856	1.78e-244	-	-	-	S	-	-	-	Heparinase II/III-like protein
MKNPMADF_03857	4.53e-284	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2264)
MKNPMADF_03858	1.33e-208	-	3.2.1.180	GH88	O	ko:K18581	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
MKNPMADF_03859	2.75e-192	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKNPMADF_03860	1.38e-269	-	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_03861	1.43e-246	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03862	3.19e-177	-	-	-	G	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03863	3.59e-173	-	-	-	G	-	-	-	ABC transporter (permease)
MKNPMADF_03865	0.0	-	-	-	-	-	-	-	-
MKNPMADF_03866	4.05e-102	-	-	-	-	-	-	-	-
MKNPMADF_03867	6.97e-135	-	-	-	-	-	-	-	-
MKNPMADF_03868	6.62e-233	-	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein domain
MKNPMADF_03869	1.7e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKNPMADF_03870	0.0	-	-	-	S	ko:K07793	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite tricarboxylate transporter TctA family
MKNPMADF_03872	8.64e-227	-	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
MKNPMADF_03873	2.45e-215	-	4.3.3.7	-	EM	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Dihydrodipicolinate synthetase family
MKNPMADF_03874	1.27e-221	-	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Bacterial fructose-1,6-bisphosphatase, glpX-encoded
MKNPMADF_03875	1.98e-141	-	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
MKNPMADF_03876	3.73e-239	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
MKNPMADF_03877	6.17e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose/Galactose Isomerase
MKNPMADF_03878	3.1e-172	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MKNPMADF_03879	2.28e-173	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_03880	9.61e-271	-	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MKNPMADF_03881	9.17e-303	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
MKNPMADF_03882	6.56e-64	-	-	-	S	ko:K07068	-	ko00000	DUF35 OB-fold domain, acyl-CoA-associated
MKNPMADF_03883	1.34e-260	-	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Thiolase, C-terminal domain
MKNPMADF_03884	0.0	-	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MKNPMADF_03885	2.25e-118	-	-	-	S	-	-	-	DNA-binding protein with PD1-like DNA-binding motif
MKNPMADF_03886	8.64e-177	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_03887	3.28e-271	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
MKNPMADF_03888	2.6e-107	-	-	-	G	ko:K11689	ko02020,map02020	ko00000,ko00001,ko02000	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_03889	9.18e-242	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKNPMADF_03890	3.21e-168	-	-	-	K	ko:K19333	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_03891	8.09e-260	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKNPMADF_03894	5.2e-54	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
MKNPMADF_03895	6.56e-222	-	-	-	P	ko:K07217	-	ko00000	Catalase
MKNPMADF_03896	1.66e-216	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
MKNPMADF_03897	2.23e-263	-	-	-	L	ko:K07487	-	ko00000	Transposase
MKNPMADF_03898	0.0	-	-	-	F	-	-	-	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine
MKNPMADF_03899	2.54e-77	ydeP9	-	-	K	-	-	-	HxlR-like helix-turn-helix
MKNPMADF_03900	2.85e-207	-	-	-	S	ko:K06911	-	ko00000	Belongs to the pirin family
MKNPMADF_03901	1.98e-201	ycnC	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03902	1.11e-171	-	-	-	S	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
MKNPMADF_03903	0.000275	rapA	-	-	S	ko:K06359,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKNPMADF_03904	3.3e-94	lysR1	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03905	3.35e-232	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_03906	4.66e-153	-	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MKNPMADF_03907	1.11e-126	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03908	1.6e-305	oppF	-	-	P	ko:K02031,ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03909	6.48e-200	ytnJ	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_03911	5.54e-81	ssuE	1.5.1.38	-	S	ko:K00299	ko00740,ko00920,ko01100,map00740,map00920,map01100	ko00000,ko00001,ko01000	FMN reductase
MKNPMADF_03912	2.85e-187	hipO2	-	-	E	ko:K01436,ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
MKNPMADF_03913	7.86e-68	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_03914	7.9e-38	ytnI	-	-	O	-	-	-	COG0695 Glutaredoxin and related proteins
MKNPMADF_03915	2.47e-59	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_03916	8.38e-105	yxeO	-	-	E	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	amino acid ABC transporter ATP-binding protein
MKNPMADF_03917	1.31e-89	yxeN	-	-	E	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03918	5.97e-64	-	-	-	ET	ko:K02030,ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	extracellular solute-binding
MKNPMADF_03919	3.76e-110	ytmO	-	-	C	-	-	-	Alkane 1-monooxygenase
MKNPMADF_03920	2.91e-208	ytnJ	-	-	C	-	-	-	Monooxygenase
MKNPMADF_03921	2.61e-221	-	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_03922	3.59e-110	-	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MKNPMADF_03923	3.94e-77	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
MKNPMADF_03924	4.21e-143	metN_1	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNPMADF_03925	5.42e-101	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	NLPA lipoprotein
MKNPMADF_03926	3.65e-87	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MKNPMADF_03927	6.19e-42	-	-	-	L	-	-	-	Transposase
MKNPMADF_03928	1.13e-156	-	-	-	L	ko:K07497	-	ko00000	HTH-like domain
MKNPMADF_03929	4.22e-84	ykuG	-	-	M	-	-	-	Putative peptidoglycan binding domain
MKNPMADF_03930	4.78e-46	-	-	-	-	-	-	-	-
MKNPMADF_03931	8.34e-198	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKNPMADF_03932	6.07e-165	-	-	-	S	ko:K07010	-	ko00000,ko01002	Peptidase C26
MKNPMADF_03933	7.75e-258	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKNPMADF_03934	1.68e-177	-	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
MKNPMADF_03935	0.0	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_03936	0.0	sfuB	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03937	1.05e-250	fbpC	3.6.3.30	-	P	ko:K02010,ko:K02052	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKNPMADF_03938	1.25e-239	-	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_03940	6.2e-114	-	-	-	-	-	-	-	-
MKNPMADF_03941	3.89e-285	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MKNPMADF_03942	1.26e-286	-	-	-	S	ko:K12941,ko:K21613	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MKNPMADF_03943	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
MKNPMADF_03944	3.89e-284	-	-	-	E	-	-	-	Peptidase family M28
MKNPMADF_03945	2.36e-246	-	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03946	6.4e-233	-	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_03947	1.12e-214	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	N-terminal TM domain of oligopeptide transport permease C
MKNPMADF_03948	3.52e-201	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_03949	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKNPMADF_03951	3.47e-210	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03952	2.83e-249	-	-	-	L	ko:K07486	-	ko00000	COG3547 Transposase and inactivated derivatives
MKNPMADF_03953	4.66e-196	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
MKNPMADF_03954	1.93e-265	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
MKNPMADF_03955	1.13e-66	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
MKNPMADF_03956	7.7e-67	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_03957	1.43e-291	celD	2.7.1.207	-	G	ko:K02761,ko:K02787,ko:K02788	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNPMADF_03958	6.38e-61	-	-	-	-	-	-	-	-
MKNPMADF_03959	4.18e-315	-	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MKNPMADF_03961	3.24e-143	-	-	-	S	-	-	-	CAAX protease self-immunity
MKNPMADF_03962	2.28e-113	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
MKNPMADF_03963	0.0	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
MKNPMADF_03969	3.8e-138	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MKNPMADF_03972	2.59e-41	-	-	-	L	ko:K07483	-	ko00000	Transposase
MKNPMADF_03973	1.41e-58	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
MKNPMADF_03974	1.62e-87	ytcD	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_03975	3.41e-128	-	1.6.5.2	-	S	ko:K00355	ko00130,ko01110,ko05200,ko05225,ko05418,map00130,map01110,map05200,map05225,map05418	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
MKNPMADF_03977	1.59e-144	-	-	-	S	-	-	-	Enoyl-(Acyl carrier protein) reductase
MKNPMADF_03978	2.14e-65	-	-	-	S	-	-	-	Agrobacterium tumefaciens protein Atu4866
MKNPMADF_03979	1.05e-162	-	-	-	K	-	-	-	AraC-type transcriptional regulator N-terminus
MKNPMADF_03980	2.28e-172	-	-	-	L	-	-	-	IstB-like ATP binding protein
MKNPMADF_03981	0.0	-	-	-	L	-	-	-	Transposase
MKNPMADF_03983	2.58e-29	-	-	-	S	-	-	-	Domain of unknown function (DUF3784)
MKNPMADF_03984	5.15e-305	-	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MKNPMADF_03985	1.97e-99	cps1C	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MKNPMADF_03986	2.04e-63	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MKNPMADF_03987	4.33e-14	-	-	-	M	-	-	-	O-Antigen ligase
MKNPMADF_03988	3.31e-134	-	-	-	M	-	-	-	Glycosyl transferases group 1
MKNPMADF_03989	2.11e-88	-	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
MKNPMADF_03990	1.19e-102	-	-	-	GM	-	-	-	NAD(P)H-binding
MKNPMADF_03991	5.2e-160	-	-	-	F	-	-	-	ATP-grasp domain
MKNPMADF_03992	2.52e-196	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
MKNPMADF_03993	1.98e-308	pglF	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
MKNPMADF_03994	7.42e-199	-	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MKNPMADF_03995	8.01e-201	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MKNPMADF_03999	6.12e-227	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
MKNPMADF_04000	1.99e-260	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MKNPMADF_04001	5.16e-233	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
MKNPMADF_04002	0.0	gerAA	-	-	EG	ko:K06288,ko:K06310	-	ko00000	Spore germination protein
MKNPMADF_04003	1.43e-248	-	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MKNPMADF_04004	1.02e-129	-	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
MKNPMADF_04005	1.9e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
MKNPMADF_04006	1.85e-58	-	-	-	-	-	-	-	-
MKNPMADF_04010	4.19e-63	-	-	-	S	-	-	-	LXG domain of WXG superfamily
MKNPMADF_04011	2.12e-23	-	-	-	S	-	-	-	Family of unknown function (DUF5344)
MKNPMADF_04012	1.22e-100	-	-	-	S	-	-	-	Bacterial PH domain
MKNPMADF_04013	1.88e-167	ycdF	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Short-chain dehydrogenase reductase sdr
MKNPMADF_04014	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
MKNPMADF_04015	1.97e-151	mdmC1	-	-	S	-	-	-	O-methyltransferase
MKNPMADF_04016	3.01e-197	-	-	-	K	-	-	-	LysR substrate binding domain
MKNPMADF_04017	3.23e-58	sdpR	-	-	K	-	-	-	transcriptional
MKNPMADF_04018	3.48e-132	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MKNPMADF_04019	3.61e-171	-	-	-	G	-	-	-	Phosphoenolpyruvate phosphomutase
MKNPMADF_04020	1.17e-205	-	-	-	E	-	-	-	Glyoxalase-like domain
MKNPMADF_04021	4.1e-237	-	-	-	P	ko:K02051,ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
MKNPMADF_04022	6.08e-177	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MKNPMADF_04023	7.02e-163	ssuB	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system
MKNPMADF_04024	4.48e-109	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
MKNPMADF_04025	1.64e-229	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system ascorbate-specific transporter subunit IIC
MKNPMADF_04026	2.06e-42	-	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_04027	3.48e-219	-	2.7.1.194	-	GKT	ko:K02821,ko:K03483	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000,ko03000	COG3711 Transcriptional antiterminator
MKNPMADF_04028	1.5e-189	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MKNPMADF_04029	7.55e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_04030	2.12e-178	-	-	-	S	-	-	-	Alpha/beta hydrolase family
MKNPMADF_04031	2.42e-236	-	-	-	GM	-	-	-	NAD dependent epimerase/dehydratase family
MKNPMADF_04033	0.0	tetM	-	-	J	ko:K18220	-	br01600,ko00000,ko01504	Elongation factor G, domain IV
MKNPMADF_04035	1.37e-292	-	-	-	S	-	-	-	Putative esterase
MKNPMADF_04036	2.73e-118	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
MKNPMADF_04037	5.71e-52	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
MKNPMADF_04038	5.75e-152	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
MKNPMADF_04040	8.24e-271	-	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
MKNPMADF_04041	2.29e-308	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MKNPMADF_04042	0.0	-	-	-	S	-	-	-	Membrane
MKNPMADF_04043	3.78e-74	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MKNPMADF_04044	1.19e-224	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MKNPMADF_04045	6.69e-114	-	-	-	S	-	-	-	OHCU decarboxylase
MKNPMADF_04046	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MKNPMADF_04047	7.44e-297	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKNPMADF_04048	2.55e-310	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MKNPMADF_04049	2.32e-121	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MKNPMADF_04050	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MKNPMADF_04051	1.15e-202	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MKNPMADF_04052	4.28e-129	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
MKNPMADF_04053	6.78e-225	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MKNPMADF_04054	7.16e-232	-	-	-	P	-	-	-	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MKNPMADF_04055	7.26e-185	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_04056	1.55e-179	-	-	-	P	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKNPMADF_04058	1.55e-239	-	-	-	P	-	-	-	NMT1-like family
MKNPMADF_04059	5.82e-192	-	-	-	P	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_04060	3.65e-173	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MKNPMADF_04061	0.0	fhuB5	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MKNPMADF_04062	1.69e-232	cbrA5	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ferrichrome ABC transporter substrate-binding protein
MKNPMADF_04063	3.22e-69	-	-	-	FG	ko:K02503	-	ko00000,ko04147	Scavenger mRNA decapping enzyme C-term binding
MKNPMADF_04064	4.01e-100	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
MKNPMADF_04065	1.11e-101	-	-	-	S	-	-	-	ASCH
MKNPMADF_04066	0.0	-	-	-	G	-	-	-	Belongs to the glycosyl hydrolase 2 family
MKNPMADF_04067	0.0	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
MKNPMADF_04068	2.18e-157	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNPMADF_04069	3.84e-231	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_04070	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MKNPMADF_04071	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MKNPMADF_04072	1.3e-218	scrR	-	-	K	ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MKNPMADF_04073	2.7e-145	ydgI	-	-	C	-	-	-	nitroreductase
MKNPMADF_04074	7.32e-79	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_04075	8.24e-144	-	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
MKNPMADF_04076	4.77e-12	-	-	-	-	-	-	-	-
MKNPMADF_04077	7.95e-172	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
MKNPMADF_04078	2.25e-267	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
MKNPMADF_04079	6.8e-227	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MKNPMADF_04080	1.06e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MKNPMADF_04081	0.0	-	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
MKNPMADF_04082	1.87e-220	-	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_04083	1.03e-205	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_04084	2.31e-175	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MKNPMADF_04085	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MKNPMADF_04086	4.68e-158	-	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
MKNPMADF_04087	1.46e-117	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_04088	6.11e-27	-	-	-	-	-	-	-	-
MKNPMADF_04089	2.12e-27	tnpB	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MKNPMADF_04091	5e-100	-	-	-	-	-	-	-	-
MKNPMADF_04092	1.77e-94	-	5.3.1.1	-	J	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Triosephosphate isomerase
MKNPMADF_04093	2.04e-63	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MKNPMADF_04094	9.4e-67	-	-	-	G	-	-	-	Ribose/Galactose Isomerase
MKNPMADF_04095	7.55e-153	-	-	-	G	-	-	-	Dak1 domain
MKNPMADF_04096	4.23e-95	-	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Pfam:DUF1498
MKNPMADF_04097	3.25e-190	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
MKNPMADF_04098	3.1e-45	-	-	-	G	-	-	-	PTS system, Lactose/Cellobiose specific IIB subunit
MKNPMADF_04099	7.71e-64	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNPMADF_04100	5.27e-170	-	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-bisphosphate aldolase class-II
MKNPMADF_04101	2.2e-77	-	-	-	K	-	-	-	DeoR C terminal sensor domain
MKNPMADF_04102	0.0	gltD	1.3.1.1	-	E	ko:K17722	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MKNPMADF_04103	3.54e-295	preA	1.3.1.1	-	CF	ko:K17723	ko00240,ko00410,ko00770,ko01100,map00240,map00410,map00770,map01100	ko00000,ko00001,ko00002,ko01000	dihydroorotate dehydrogenase
MKNPMADF_04104	0.0	hydA	3.5.2.2	-	F	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Amidohydrolase family
MKNPMADF_04106	6.58e-293	-	3.5.1.6, 3.5.1.87	-	E	ko:K06016	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MKNPMADF_04107	0.0	-	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKNPMADF_04108	1.57e-83	-	-	-	F	-	-	-	PFAM AIG2 family protein
MKNPMADF_04109	5.61e-29	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MKNPMADF_04110	3.41e-205	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_04113	3.96e-226	-	-	-	S	-	-	-	Tetratricopeptide repeat
MKNPMADF_04114	0.0	-	-	-	T	-	-	-	Domain present in phytochromes and cGMP-specific phosphodiesterases.
MKNPMADF_04115	0.0	-	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_04116	4.65e-195	-	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MKNPMADF_04117	3.64e-178	-	-	-	S	-	-	-	Protein of unknown function (DUF3100)
MKNPMADF_04118	7.53e-94	-	-	-	S	-	-	-	An automated process has identified a potential problem with this gene model
MKNPMADF_04119	2.49e-181	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
MKNPMADF_04120	6.06e-156	epsB	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
MKNPMADF_04121	2.53e-149	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
MKNPMADF_04122	1.42e-217	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MKNPMADF_04123	6.74e-101	-	-	-	S	-	-	-	Tetratrico peptide repeat
MKNPMADF_04124	7.21e-65	-	-	-	E	-	-	-	LysE type translocator
MKNPMADF_04125	4.82e-118	ydbC	-	-	G	-	-	-	Domain of unknown function (DUF4937
MKNPMADF_04126	4.71e-88	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_04127	7.42e-102	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
MKNPMADF_04128	1.73e-97	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
MKNPMADF_04129	5.4e-22	-	-	-	G	-	-	-	Major Facilitator Superfamily
MKNPMADF_04130	1.47e-70	-	-	-	G	-	-	-	Major Facilitator Superfamily
MKNPMADF_04131	4.35e-282	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MKNPMADF_04132	7.86e-242	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MKNPMADF_04133	5.45e-207	tagU	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MKNPMADF_04134	5.58e-59	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MKNPMADF_04135	2.55e-287	-	-	-	-	-	-	-	-
MKNPMADF_04136	5.12e-306	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKNPMADF_04137	3.63e-289	lytE	-	-	M	-	-	-	NlpC/P60 family
MKNPMADF_04139	1.88e-183	-	-	-	Q	-	-	-	N-acetyltransferase
MKNPMADF_04140	6.23e-102	yisT	-	-	S	-	-	-	DinB family
MKNPMADF_04141	2.04e-117	-	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MKNPMADF_04142	0.0	pip	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
MKNPMADF_04143	1.55e-94	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKNPMADF_04144	1.81e-172	estA	-	CE1	S	ko:K03930	-	ko00000,ko01000	Putative esterase
MKNPMADF_04145	4.67e-139	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKNPMADF_04146	2.51e-239	-	-	-	S	ko:K06308	-	ko00000	Spore germination B3/ GerAC like, C-terminal
MKNPMADF_04147	8.97e-253	-	-	-	E	-	-	-	Spore germination protein
MKNPMADF_04148	0.0	-	-	-	P	-	-	-	Spore gernimation protein GerA
MKNPMADF_04149	2.57e-78	-	-	-	S	-	-	-	DNA-directed RNA polymerase subunit beta
MKNPMADF_04150	5.39e-179	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MKNPMADF_04151	1.6e-177	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
MKNPMADF_04152	1.9e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
MKNPMADF_04153	1.68e-60	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
MKNPMADF_04154	1.6e-60	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MKNPMADF_04155	2.08e-68	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
MKNPMADF_04156	1.35e-168	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
MKNPMADF_04157	5.47e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
MKNPMADF_04158	7.83e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKNPMADF_04159	4.51e-21	ywmB	-	-	S	-	-	-	TATA-box binding
MKNPMADF_04160	3.58e-73	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MKNPMADF_04161	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKNPMADF_04162	3.25e-193	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKNPMADF_04163	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKNPMADF_04164	2.89e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKNPMADF_04165	2.37e-47	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKNPMADF_04166	2.78e-28	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKNPMADF_04167	3.41e-170	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MKNPMADF_04168	1.25e-10	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase I chain
MKNPMADF_04169	4.29e-40	-	-	-	S	-	-	-	Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter
MKNPMADF_04170	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
MKNPMADF_04171	1.76e-114	panZ	-	-	K	-	-	-	-acetyltransferase
MKNPMADF_04172	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKNPMADF_04173	8.8e-302	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKNPMADF_04174	6.32e-122	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MKNPMADF_04175	1.59e-104	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
MKNPMADF_04176	8.18e-182	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	Chemotaxis
MKNPMADF_04177	3.25e-92	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKNPMADF_04178	1.61e-119	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
MKNPMADF_04179	1.29e-76	-	-	-	S	-	-	-	Regulator of ribonuclease activity B
MKNPMADF_04180	5.07e-230	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKNPMADF_04181	1.3e-94	ywlB	1.20.4.1, 2.3.1.1	-	E	ko:K00537,ko:K00619	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetyltransferase family. ArgA subfamily
MKNPMADF_04182	5.49e-142	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
MKNPMADF_04183	3.3e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKNPMADF_04184	1.04e-230	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKNPMADF_04185	0.0	cdr	1.11.1.1	-	P	ko:K05910	-	ko00000,ko01000	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKNPMADF_04186	1.69e-97	-	-	-	-	-	-	-	-
MKNPMADF_04187	1.27e-140	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MKNPMADF_04188	2.08e-54	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MKNPMADF_04189	2.94e-300	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKNPMADF_04190	3.14e-228	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
MKNPMADF_04191	4.31e-280	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKNPMADF_04192	8.05e-149	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKNPMADF_04193	9.14e-204	fbaA	4.1.2.13	-	G	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
MKNPMADF_04194	1.05e-77	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	response regulator
MKNPMADF_04195	1.29e-112	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
MKNPMADF_04196	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKNPMADF_04197	2.54e-90	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKNPMADF_04198	4.32e-140	kstR2_2	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_04199	1.57e-260	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
MKNPMADF_04200	6.82e-192	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
MKNPMADF_04201	2.87e-270	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
MKNPMADF_04202	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
MKNPMADF_04203	1.67e-271	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MKNPMADF_04204	6.27e-95	-	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
MKNPMADF_04205	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MKNPMADF_04206	1.05e-97	ywiB	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_04207	5.79e-214	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
MKNPMADF_04208	3.6e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MKNPMADF_04209	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MKNPMADF_04210	2.71e-198	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_04211	0.0	-	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MKNPMADF_04212	1.95e-127	ywhD	-	-	S	-	-	-	YwhD family
MKNPMADF_04213	1.65e-247	-	-	-	F	-	-	-	S-adenosylhomocysteine deaminase activity
MKNPMADF_04214	2.4e-160	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
MKNPMADF_04215	9.83e-37	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
MKNPMADF_04216	3.97e-57	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
MKNPMADF_04218	9.17e-116	ywgA	-	-	-	ko:K09388	-	ko00000	-
MKNPMADF_04219	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
MKNPMADF_04220	9.03e-264	gltP	-	-	C	-	-	-	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKNPMADF_04221	7.65e-185	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MKNPMADF_04222	4.3e-231	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
MKNPMADF_04223	4.29e-180	-	5.3.3.18	-	I	ko:K15866	ko00360,ko01120,map00360,map01120	ko00000,ko00001,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
MKNPMADF_04224	2.61e-184	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
MKNPMADF_04225	5.82e-180	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKNPMADF_04226	3.16e-64	-	-	-	-	-	-	-	-
MKNPMADF_04227	3.05e-245	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
MKNPMADF_04228	6.98e-210	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MKNPMADF_04229	1.46e-207	natA1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_04230	9.31e-84	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
MKNPMADF_04231	7.33e-163	-	-	-	-	-	-	-	-
MKNPMADF_04232	6.58e-101	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
MKNPMADF_04233	5.01e-106	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MKNPMADF_04234	4.91e-78	ywdK	-	-	S	-	-	-	small membrane protein
MKNPMADF_04235	1.58e-140	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNPMADF_04236	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKNPMADF_04237	1.79e-61	-	-	-	S	-	-	-	Family of unknown function (DUF5327)
MKNPMADF_04238	1.24e-170	polC1	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases
MKNPMADF_04239	8.8e-214	-	-	-	T	ko:K07182	-	ko00000	Putative nucleotidyltransferase substrate binding domain
MKNPMADF_04240	7.97e-294	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
MKNPMADF_04241	3.31e-222	-	-	-	S	ko:K07120	-	ko00000	Pfam:AmoA
MKNPMADF_04242	1.91e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKNPMADF_04243	2.54e-297	-	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_04244	1.29e-190	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MKNPMADF_04245	0.0	hutH	4.3.1.3	-	E	ko:K01745	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Histidine ammonia-lyase
MKNPMADF_04246	8.36e-63	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
MKNPMADF_04247	1.65e-159	-	-	-	E	-	-	-	AzlC protein
MKNPMADF_04248	0.0	gntR9	-	-	K	-	-	-	Alanine-glyoxylate amino-transferase
MKNPMADF_04249	6.65e-146	XK27_07210	-	-	S	-	-	-	B3/4 domain
MKNPMADF_04250	6.59e-296	megL	4.4.1.11	-	E	ko:K01761	ko00270,ko00450,map00270,map00450	ko00000,ko00001,ko01000	methionine gamma-lyase
MKNPMADF_04251	1.21e-240	-	-	-	I	-	-	-	Fatty acid desaturase
MKNPMADF_04252	0.0	-	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	Glutamine synthetase, catalytic domain
MKNPMADF_04253	1.72e-91	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
MKNPMADF_04254	3.78e-96	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_04255	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKNPMADF_04256	2.81e-101	bdbA	-	-	CO	-	-	-	Thioredoxin
MKNPMADF_04257	3.44e-91	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
MKNPMADF_04258	0.0	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
MKNPMADF_04260	3.41e-108	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
MKNPMADF_04261	6.6e-241	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
MKNPMADF_04262	5.38e-167	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
MKNPMADF_04263	5.02e-311	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
MKNPMADF_04264	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKNPMADF_04265	3.44e-281	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
MKNPMADF_04266	4.66e-56	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
MKNPMADF_04267	2.09e-72	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
MKNPMADF_04268	2.04e-128	-	-	-	S	-	-	-	UPF0302 domain
MKNPMADF_04269	7.92e-192	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MKNPMADF_04270	3.27e-204	XK27_03890	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MKNPMADF_04271	1.14e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MKNPMADF_04272	1.8e-221	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MKNPMADF_04274	8.04e-187	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
MKNPMADF_04275	0.0	dapE	-	-	E	-	-	-	Peptidase dimerisation domain
MKNPMADF_04276	5.24e-278	-	-	-	S	-	-	-	Acetyltransferase
MKNPMADF_04277	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKNPMADF_04278	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKNPMADF_04279	1.31e-269	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
MKNPMADF_04280	1.96e-121	-	-	-	S	-	-	-	DinB superfamily
MKNPMADF_04281	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
MKNPMADF_04282	0.0	ywjA	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MKNPMADF_04283	1.66e-216	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
MKNPMADF_04284	2.15e-139	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MKNPMADF_04285	6.82e-141	yrbG	-	-	S	-	-	-	membrane
MKNPMADF_04286	3.44e-209	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MKNPMADF_04287	1.28e-105	hxlB	5.3.1.27	-	M	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
MKNPMADF_04288	1.02e-123	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Orotidine 5'-phosphate decarboxylase / HUMPS family
MKNPMADF_04289	7.63e-58	hxlR	-	-	K	-	-	-	HxlR-like helix-turn-helix
MKNPMADF_04290	1.99e-194	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKNPMADF_04292	8.28e-176	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
MKNPMADF_04293	9.27e-219	-	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
MKNPMADF_04294	2.15e-131	-	-	-	K	-	-	-	GrpB protein
MKNPMADF_04295	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKNPMADF_04296	4.73e-97	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
MKNPMADF_04297	2.82e-117	-	-	-	-	-	-	-	-
MKNPMADF_04298	0.0	-	-	-	-	-	-	-	-
MKNPMADF_04299	3.28e-87	-	-	-	-	-	-	-	-
MKNPMADF_04300	4.06e-84	-	-	-	-	-	-	-	-
MKNPMADF_04301	4.41e-96	-	-	-	S	-	-	-	GNAT acetyltransferase
MKNPMADF_04302	1.32e-250	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKNPMADF_04304	0.0	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_04306	0.0	-	-	-	-	-	-	-	-
MKNPMADF_04307	3.51e-145	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_04308	3.47e-106	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	pfam abc
MKNPMADF_04309	4.27e-130	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	NMT1-like family
MKNPMADF_04310	1.8e-121	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MKNPMADF_04311	9.62e-66	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
MKNPMADF_04312	1.05e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF4242)
MKNPMADF_04313	1.07e-114	-	-	-	I	-	-	-	acyl-CoA dehydrogenase
MKNPMADF_04314	0.0	sdcS	-	-	P	ko:K14445	-	ko00000,ko02000	Sodium:sulfate symporter transmembrane region
MKNPMADF_04315	9.25e-155	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
MKNPMADF_04316	0.0	-	2.7.13.3	-	T	ko:K02476,ko:K11614,ko:K11637	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
MKNPMADF_04317	1.84e-147	M1-740	-	-	I	-	-	-	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MKNPMADF_04318	6.16e-209	-	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MKNPMADF_04319	4.52e-77	-	-	-	S	-	-	-	CHY zinc finger
MKNPMADF_04320	5.71e-284	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MKNPMADF_04323	1.14e-57	sdpI	-	-	S	-	-	-	integral membrane protein
MKNPMADF_04324	1.18e-275	-	-	-	EGP	-	-	-	Transmembrane secretion effector
MKNPMADF_04325	1.67e-125	-	-	-	S	ko:K09962	-	ko00000	protein conserved in bacteria
MKNPMADF_04326	3.9e-171	ubiE	-	-	Q	-	-	-	Methyltransferase type 11
MKNPMADF_04327	1.85e-300	-	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MKNPMADF_04328	2.2e-60	phhB	3.5.4.33, 4.2.1.96	-	H	ko:K01724,ko:K11991	ko00790,map00790	ko00000,ko00001,ko01000,ko03016,ko04147	pterin-4-alpha-carbinolamine dehydratase
MKNPMADF_04329	7.06e-74	eaeH	-	-	M	ko:K13735	ko05100,map05100	ko00000,ko00001	LysM domain
MKNPMADF_04330	1.38e-88	-	-	-	S	-	-	-	YtkA-like
MKNPMADF_04331	0.0	-	-	-	T	-	-	-	Histidine kinase
MKNPMADF_04332	9.73e-155	-	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_04333	4.3e-230	-	-	-	S	-	-	-	amine dehydrogenase activity
MKNPMADF_04334	1.81e-239	-	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
MKNPMADF_04336	6.66e-43	-	-	-	-	-	-	-	-
MKNPMADF_04337	1.83e-10	-	-	-	-	-	-	-	-
MKNPMADF_04338	7.15e-137	M1-1017	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MKNPMADF_04339	3.5e-70	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_04340	2.72e-135	-	-	-	S	-	-	-	DUF218 domain
MKNPMADF_04341	6.56e-190	degV	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_04342	0.0	mutS1	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKNPMADF_04343	1.33e-52	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKNPMADF_04344	2.26e-288	yciC	-	-	S	-	-	-	GTPases (G3E family)
MKNPMADF_04345	4.46e-165	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
MKNPMADF_04347	4.53e-239	mhqA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
MKNPMADF_04348	0.0	-	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182	ko00130,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the UbiD family
MKNPMADF_04349	8.72e-147	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MKNPMADF_04350	6.11e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MKNPMADF_04351	3.63e-305	atoE	-	-	I	ko:K02106	ko02020,map02020	ko00000,ko00001	Short chain fatty acid transporter
MKNPMADF_04352	3.72e-239	malR	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_04353	3.96e-190	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
MKNPMADF_04354	1.83e-314	-	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
MKNPMADF_04355	2.26e-303	malE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
MKNPMADF_04356	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
MKNPMADF_04358	6.73e-305	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
MKNPMADF_04359	4.17e-283	codB	-	-	F	ko:K10974	-	ko00000,ko02000	cytosine purines uracil thiamine allantoin
MKNPMADF_04360	0.0	-	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MKNPMADF_04361	2.25e-284	lhgO	1.1.5.3	-	S	ko:K00111,ko:K15736	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
MKNPMADF_04362	1e-279	-	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
MKNPMADF_04363	0.0	-	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
MKNPMADF_04364	2.28e-149	-	-	-	K	-	-	-	COG2186 Transcriptional regulators
MKNPMADF_04365	2.34e-151	-	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
MKNPMADF_04366	0.0	-	-	-	S	-	-	-	Tripartite ATP-independent periplasmic transporter, DctM component
MKNPMADF_04367	1.03e-235	-	-	-	S	ko:K07080	-	ko00000	NMT1-like family
MKNPMADF_04368	2.81e-200	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
MKNPMADF_04369	2.16e-244	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
MKNPMADF_04370	2.43e-270	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MKNPMADF_04371	8.57e-98	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_04372	1.45e-236	-	-	-	G	-	-	-	Bacterial extracellular solute-binding protein, family 7
MKNPMADF_04373	5.63e-154	kdgR	-	-	K	-	-	-	FCD
MKNPMADF_04374	1.13e-247	yjmC	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MKNPMADF_04375	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
MKNPMADF_04376	7.87e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MKNPMADF_04377	5.43e-122	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
MKNPMADF_04378	4.1e-214	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
MKNPMADF_04379	9.37e-96	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
MKNPMADF_04380	9.43e-139	-	-	-	S	-	-	-	CGNR zinc finger
MKNPMADF_04381	1.45e-102	-	-	-	-	-	-	-	-
MKNPMADF_04382	0.0	-	-	-	T	-	-	-	Carbon starvation protein
MKNPMADF_04383	8.01e-173	-	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
MKNPMADF_04384	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_04385	1.36e-131	-	-	-	K	-	-	-	Transcriptional regulator
MKNPMADF_04386	0.0	ydfJ	-	-	S	ko:K07003	-	ko00000	MMPL family
MKNPMADF_04387	1.2e-255	-	-	-	S	-	-	-	domain protein
MKNPMADF_04388	1.74e-226	oppF3	-	-	E	ko:K02032	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_04389	1.49e-224	oppD3	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_04390	1.23e-203	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_04391	6.02e-220	appB	-	-	P	ko:K02033,ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_04392	0.0	-	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
MKNPMADF_04393	5.96e-12	-	-	-	-	-	-	-	-
MKNPMADF_04394	1.47e-113	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
MKNPMADF_04395	1.12e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MKNPMADF_04397	1.35e-157	-	-	-	G	-	-	-	Class II Aldolase and Adducin N-terminal domain
MKNPMADF_04398	1.7e-268	-	-	-	G	-	-	-	COG1593 TRAP-type C4-dicarboxylate transport system, large permease component
MKNPMADF_04399	1.06e-100	-	-	-	G	-	-	-	Tripartite ATP-independent periplasmic transporters, DctQ component
MKNPMADF_04400	4.79e-91	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKNPMADF_04401	1.43e-107	-	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MKNPMADF_04402	9.87e-239	tdh	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
MKNPMADF_04403	3.44e-141	-	-	-	K	-	-	-	FCD domain
MKNPMADF_04404	1.73e-306	-	2.7.1.219, 2.7.1.220	-	S	ko:K22129	-	ko00000,ko01000	Putative nucleotide-binding of sugar-metabolising enzyme
MKNPMADF_04405	7.26e-71	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
MKNPMADF_04407	5.54e-73	-	-	-	S	-	-	-	nucleotidyltransferase activity
MKNPMADF_04408	5.06e-20	-	-	-	Q	ko:K15256	-	ko00000,ko01000,ko03016	O-methyltransferase
MKNPMADF_04410	0.0	XK27_03440	3.1.21.5	-	V	ko:K01156	-	ko00000,ko01000,ko02048	Type III restriction enzyme, res subunit
MKNPMADF_04411	1.01e-170	mod	2.1.1.72	-	L	ko:K00571,ko:K07316	-	ko00000,ko01000,ko02048	DNA methylase
MKNPMADF_04412	1.46e-146	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent DNA helicase activity
MKNPMADF_04413	0.0	-	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MKNPMADF_04414	2.04e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKNPMADF_04415	4.04e-267	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MKNPMADF_04416	7.76e-189	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MKNPMADF_04417	1.16e-207	yycI	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_04418	7.39e-309	yycH	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_04419	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MKNPMADF_04420	2.06e-170	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MKNPMADF_04426	3.15e-314	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKNPMADF_04427	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MKNPMADF_04428	1.41e-88	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
MKNPMADF_04429	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MKNPMADF_04430	5.05e-187	yybS	-	-	S	-	-	-	membrane
MKNPMADF_04431	4.32e-48	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKNPMADF_04432	4.66e-89	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKNPMADF_04433	3.39e-60	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MKNPMADF_04434	1.39e-246	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKNPMADF_04435	1.19e-37	yyzM	-	-	S	-	-	-	protein conserved in bacteria
MKNPMADF_04436	1.18e-229	yyaD	-	-	S	-	-	-	Membrane
MKNPMADF_04437	3.3e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
MKNPMADF_04438	4.44e-273	-	-	-	E	-	-	-	Aminotransferase class-V
MKNPMADF_04439	2.89e-192	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MKNPMADF_04440	3.38e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
MKNPMADF_04441	1.49e-191	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MKNPMADF_04442	2.39e-165	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MKNPMADF_04443	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKNPMADF_04444	4.9e-315	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKNPMADF_04445	9.02e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
MKNPMADF_04446	1.24e-177	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKNPMADF_04447	2.54e-72	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKNPMADF_04448	3.58e-22	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MKNPMADF_04449	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKNPMADF_04450	3.45e-264	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKNPMADF_04451	1.15e-43	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
MKNPMADF_04452	2.58e-255	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKNPMADF_04453	9.83e-12	yqbO1	-	-	S	-	-	-	Domain of unknown function (DUF370)
MKNPMADF_04454	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKNPMADF_04455	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKNPMADF_04456	1.59e-11	-	-	-	-	-	-	-	-
MKNPMADF_04457	7.47e-234	-	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNPMADF_04458	3.67e-123	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Bacitracin ABC transporter permease
MKNPMADF_04459	1.6e-17	-	-	-	-	-	-	-	-
MKNPMADF_04460	8.78e-185	yaaC	-	-	S	-	-	-	YaaC-like Protein
MKNPMADF_04461	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MKNPMADF_04462	1.62e-304	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MKNPMADF_04463	4.49e-280	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKNPMADF_04464	1.3e-185	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MKNPMADF_04465	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
MKNPMADF_04466	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MKNPMADF_04467	4.4e-288	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
MKNPMADF_04468	4.62e-238	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase
MKNPMADF_04469	3.13e-309	nhaC_2	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
MKNPMADF_04470	3.52e-297	-	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MKNPMADF_04471	6.52e-290	-	2.5.1.48, 4.4.1.11	-	E	ko:K01739,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MKNPMADF_04472	3.6e-286	-	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MKNPMADF_04473	1.16e-241	-	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MKNPMADF_04474	0.0	gabD_2	1.2.1.9	-	C	ko:K00131	ko00010,ko00030,ko01100,ko01120,ko01200,map00010,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MKNPMADF_04475	1.59e-79	-	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
MKNPMADF_04476	2.39e-184	glnH	-	-	ET	ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Ligated ion channel L-glutamate- and glycine-binding site
MKNPMADF_04477	1.23e-141	glnP	-	-	E	ko:K02029,ko:K10037,ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Polar amino acid ABC transporter, inner membrane subunit
MKNPMADF_04478	1.95e-161	-	3.6.3.21	-	E	ko:K02028,ko:K10038	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
MKNPMADF_04479	1.11e-241	-	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_04480	6.47e-245	-	-	-	P	ko:K02031,ko:K16202	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MKNPMADF_04481	3.19e-214	-	-	-	EP	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_04482	1.83e-203	-	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNPMADF_04483	0.0	gsiB_3	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
MKNPMADF_04485	6.95e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKNPMADF_04486	7.88e-131	clpP1	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKNPMADF_04487	1.57e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Sigma-70, region 4
MKNPMADF_04488	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKNPMADF_04489	4.53e-51	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKNPMADF_04490	9.21e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKNPMADF_04491	1.6e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MKNPMADF_04492	7.11e-29	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA