Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HKLHMGCA_00020	1.08e-117	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HKLHMGCA_00021	6.62e-177	yhfI	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HKLHMGCA_00022	9.28e-89	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKLHMGCA_00023	7.12e-170	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HKLHMGCA_00024	1.85e-263	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HKLHMGCA_00025	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HKLHMGCA_00026	2.24e-148	yjbH	-	-	Q	-	-	-	Thioredoxin
HKLHMGCA_00027	9.08e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKLHMGCA_00028	1.29e-193	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKLHMGCA_00029	6.31e-222	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKLHMGCA_00030	7.21e-150	cutC	-	-	P	ko:K06201	-	ko00000	Participates in the control of copper homeostasis
HKLHMGCA_00031	1.6e-246	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HKLHMGCA_00032	2.68e-75	srlB	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKLHMGCA_00033	9.52e-264	XK27_05220	-	-	S	-	-	-	AI-2E family transporter
HKLHMGCA_00034	4.82e-55	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKLHMGCA_00035	1.3e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HKLHMGCA_00037	3.59e-301	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKLHMGCA_00038	2.5e-147	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HKLHMGCA_00039	1.41e-124	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKLHMGCA_00040	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKLHMGCA_00041	4.1e-223	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKLHMGCA_00042	3.22e-82	-	-	-	S	-	-	-	Protein of unknown function (DUF3397)
HKLHMGCA_00043	1.35e-100	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HKLHMGCA_00044	1.74e-224	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKLHMGCA_00045	7.01e-76	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HKLHMGCA_00046	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKLHMGCA_00047	2.81e-231	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKLHMGCA_00048	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKLHMGCA_00049	5e-253	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKLHMGCA_00050	2.34e-208	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKLHMGCA_00051	2.05e-311	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKLHMGCA_00052	9.39e-295	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKLHMGCA_00053	1.56e-93	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKLHMGCA_00054	6.45e-49	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HKLHMGCA_00055	2.06e-187	ylmH	-	-	S	-	-	-	S4 domain protein
HKLHMGCA_00056	6.52e-124	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HKLHMGCA_00057	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKLHMGCA_00058	1.41e-241	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKLHMGCA_00059	3.51e-125	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HKLHMGCA_00060	7.74e-47	-	-	-	-	-	-	-	-
HKLHMGCA_00061	5.85e-158	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKLHMGCA_00062	4.88e-276	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKLHMGCA_00063	4.94e-75	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HKLHMGCA_00064	6.7e-285	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKLHMGCA_00065	9.64e-307	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HKLHMGCA_00066	4.64e-150	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HKLHMGCA_00067	4.17e-153	-	-	-	N	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00068	4.97e-248	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKLHMGCA_00069	0.0	-	-	-	N	-	-	-	domain, Protein
HKLHMGCA_00070	2.41e-157	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HKLHMGCA_00071	1.02e-155	-	-	-	S	-	-	-	repeat protein
HKLHMGCA_00072	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKLHMGCA_00073	5.35e-220	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLHMGCA_00074	2.62e-168	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NlpC P60 family protein
HKLHMGCA_00075	1.78e-38	-	-	-	-	-	-	-	-
HKLHMGCA_00076	3.45e-240	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKLHMGCA_00077	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLHMGCA_00078	4.86e-45	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HKLHMGCA_00079	6.45e-111	-	-	-	-	-	-	-	-
HKLHMGCA_00080	3.95e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKLHMGCA_00081	4.94e-268	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HKLHMGCA_00082	8.65e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HKLHMGCA_00083	2.36e-285	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKLHMGCA_00084	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HKLHMGCA_00085	2.15e-209	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	L-malate dehydrogenase activity
HKLHMGCA_00086	2.64e-62	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HKLHMGCA_00087	1.23e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HKLHMGCA_00088	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HKLHMGCA_00089	7.94e-195	-	-	-	-	-	-	-	-
HKLHMGCA_00090	5.85e-56	-	-	-	-	-	-	-	-
HKLHMGCA_00091	1.3e-67	-	-	-	-	-	-	-	-
HKLHMGCA_00092	0.0	icaA	-	-	M	-	-	-	Glycosyl transferase family group 2
HKLHMGCA_00093	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_00094	2.51e-261	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HKLHMGCA_00095	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKLHMGCA_00096	1.91e-66	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HKLHMGCA_00097	7.08e-131	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HKLHMGCA_00098	2.56e-110	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HKLHMGCA_00099	3.01e-251	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HKLHMGCA_00100	5.47e-157	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HKLHMGCA_00101	1.01e-115	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HKLHMGCA_00102	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKLHMGCA_00103	4.44e-84	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HKLHMGCA_00104	2.42e-239	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HKLHMGCA_00105	1.18e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HKLHMGCA_00106	2.9e-56	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKLHMGCA_00107	4.48e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKLHMGCA_00108	1.29e-200	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKLHMGCA_00109	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKLHMGCA_00110	9.76e-203	-	-	-	S	-	-	-	Tetratricopeptide repeat
HKLHMGCA_00111	4.38e-286	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKLHMGCA_00112	3.21e-288	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKLHMGCA_00113	7.8e-300	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKLHMGCA_00114	9.6e-143	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HKLHMGCA_00115	1.3e-65	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HKLHMGCA_00116	6.47e-95	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKLHMGCA_00117	5.12e-31	-	-	-	-	-	-	-	-
HKLHMGCA_00118	0.0	glnPH2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKLHMGCA_00119	3.97e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00120	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKLHMGCA_00121	1.22e-116	epsB	-	-	M	-	-	-	biosynthesis protein
HKLHMGCA_00122	1.09e-33	epsB	-	-	M	-	-	-	biosynthesis protein
HKLHMGCA_00123	2.02e-156	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKLHMGCA_00124	5.54e-189	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKLHMGCA_00125	8.71e-231	cps4D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKLHMGCA_00126	3.31e-164	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HKLHMGCA_00127	7.3e-86	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HKLHMGCA_00128	8.84e-137	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HKLHMGCA_00129	9.2e-243	cps4G	-	-	M	-	-	-	Glycosyltransferase Family 4
HKLHMGCA_00130	1.91e-297	-	-	-	-	-	-	-	-
HKLHMGCA_00131	3.4e-228	cps4I	-	-	M	-	-	-	Glycosyltransferase like family 2
HKLHMGCA_00132	9.54e-88	cps4J	-	-	S	-	-	-	MatE
HKLHMGCA_00133	4.34e-220	cps4J	-	-	S	-	-	-	MatE
HKLHMGCA_00134	0.0	-	3.1.4.53	-	S	ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKLHMGCA_00135	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase System
HKLHMGCA_00136	4.24e-218	pfkB	2.7.1.56	-	H	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HKLHMGCA_00137	3.02e-175	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	DeoR C terminal sensor domain
HKLHMGCA_00138	1.55e-311	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKLHMGCA_00139	6.62e-62	-	-	-	-	-	-	-	-
HKLHMGCA_00140	8.34e-228	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKLHMGCA_00141	7.09e-180	-	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_00142	1.84e-67	-	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HKLHMGCA_00143	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HKLHMGCA_00144	1.52e-120	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKLHMGCA_00145	3.58e-129	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_00146	6.75e-269	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKLHMGCA_00147	2.84e-75	ybjQ	-	-	S	-	-	-	Belongs to the UPF0145 family
HKLHMGCA_00148	6.34e-178	-	-	-	Q	-	-	-	Methyltransferase
HKLHMGCA_00149	1.75e-43	-	-	-	-	-	-	-	-
HKLHMGCA_00150	8.67e-75	int3	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_00156	4.16e-51	-	-	-	S	-	-	-	Membrane
HKLHMGCA_00159	2.9e-24	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKLHMGCA_00161	6.04e-87	-	-	-	S	-	-	-	DNA binding
HKLHMGCA_00169	1.87e-24	-	-	-	-	-	-	-	-
HKLHMGCA_00172	7.13e-42	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HKLHMGCA_00173	2.4e-186	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HKLHMGCA_00175	4.83e-61	-	-	-	-	-	-	-	-
HKLHMGCA_00176	2.1e-17	-	-	-	-	-	-	-	-
HKLHMGCA_00178	2.21e-50	-	-	-	S	-	-	-	YopX protein
HKLHMGCA_00180	1.9e-232	-	-	-	-	-	-	-	-
HKLHMGCA_00183	4.83e-47	-	-	-	S	-	-	-	Transcriptional regulator, RinA family
HKLHMGCA_00186	5.72e-117	-	-	-	L	-	-	-	HNH nucleases
HKLHMGCA_00187	1.29e-102	-	-	-	S	-	-	-	Phage terminase, small subunit
HKLHMGCA_00188	0.0	-	-	-	S	-	-	-	Phage Terminase
HKLHMGCA_00189	2.72e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF1056)
HKLHMGCA_00190	6.97e-284	-	-	-	S	-	-	-	Phage portal protein
HKLHMGCA_00191	6e-166	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HKLHMGCA_00192	1.86e-269	-	-	-	S	-	-	-	peptidase activity
HKLHMGCA_00193	1.97e-66	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKLHMGCA_00194	6.96e-76	-	-	-	S	-	-	-	Phage head-tail joining protein
HKLHMGCA_00195	3.74e-85	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HKLHMGCA_00196	7.47e-74	-	-	-	S	-	-	-	Protein of unknown function (DUF806)
HKLHMGCA_00197	1.59e-135	-	-	-	S	-	-	-	Phage tail tube protein
HKLHMGCA_00198	1.58e-74	-	-	-	S	-	-	-	Phage tail assembly chaperone proteins, TAC
HKLHMGCA_00199	5.71e-33	-	-	-	-	-	-	-	-
HKLHMGCA_00200	0.0	-	-	-	D	-	-	-	domain protein
HKLHMGCA_00201	0.0	-	-	-	S	-	-	-	Phage tail protein
HKLHMGCA_00202	0.0	-	-	-	S	-	-	-	Phage minor structural protein
HKLHMGCA_00203	3.47e-186	-	-	-	-	-	-	-	-
HKLHMGCA_00206	3.51e-99	-	-	-	-	-	-	-	-
HKLHMGCA_00207	9.89e-33	-	-	-	-	-	-	-	-
HKLHMGCA_00208	2.31e-257	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKLHMGCA_00209	1.46e-46	-	-	-	S	-	-	-	Haemolysin XhlA
HKLHMGCA_00210	3.33e-56	-	-	-	S	-	-	-	Bacteriophage holin
HKLHMGCA_00212	1.96e-293	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Cell cycle protein
HKLHMGCA_00213	3.06e-234	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_00214	3.64e-144	-	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_00215	3.82e-184	-	-	-	P	ko:K02049	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKLHMGCA_00216	1.89e-282	ywtF_2	-	-	K	-	-	-	Cell envelope-related transcriptional attenuator domain
HKLHMGCA_00217	2.19e-131	-	-	-	L	-	-	-	Helix-turn-helix domain
HKLHMGCA_00218	1.14e-226	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	Glycosyltransferase like family 2
HKLHMGCA_00219	3.81e-87	-	-	-	-	-	-	-	-
HKLHMGCA_00220	1.38e-98	-	-	-	-	-	-	-	-
HKLHMGCA_00221	1.56e-276	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HKLHMGCA_00222	7.8e-123	-	-	-	-	-	-	-	-
HKLHMGCA_00223	7.22e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKLHMGCA_00224	7.68e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
HKLHMGCA_00225	3.96e-44	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HKLHMGCA_00226	8.8e-155	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HKLHMGCA_00227	2.11e-171	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HKLHMGCA_00228	5.67e-64	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HKLHMGCA_00229	1.92e-239	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMGCA_00230	2.92e-172	-	-	-	S	ko:K07025	-	ko00000	Haloacid dehalogenase-like hydrolase
HKLHMGCA_00231	6.33e-185	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HKLHMGCA_00232	1.88e-194	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKLHMGCA_00233	3.01e-165	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HKLHMGCA_00234	9.83e-113	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKLHMGCA_00235	3.17e-190	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKLHMGCA_00236	1.13e-175	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HKLHMGCA_00237	4.64e-294	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HKLHMGCA_00238	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKLHMGCA_00239	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLHMGCA_00240	9.74e-108	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HKLHMGCA_00241	4.46e-275	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HKLHMGCA_00242	2.95e-65	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HKLHMGCA_00243	3.28e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HKLHMGCA_00244	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKLHMGCA_00245	3.04e-71	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKLHMGCA_00246	0.0	-	-	-	G	-	-	-	Major Facilitator
HKLHMGCA_00247	3.67e-275	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKLHMGCA_00248	1.63e-121	-	-	-	-	-	-	-	-
HKLHMGCA_00249	1.24e-297	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKLHMGCA_00250	5.99e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HKLHMGCA_00251	2.41e-113	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKLHMGCA_00252	8.94e-221	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKLHMGCA_00253	1.53e-241	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKLHMGCA_00254	1.19e-169	budA	4.1.1.5	-	Q	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HKLHMGCA_00255	4.42e-248	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKLHMGCA_00256	4.52e-111	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKLHMGCA_00257	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HKLHMGCA_00258	2.54e-266	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKLHMGCA_00259	8.49e-266	pbpX2	-	-	V	-	-	-	Beta-lactamase
HKLHMGCA_00260	8.59e-27	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HKLHMGCA_00261	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMGCA_00262	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HKLHMGCA_00263	5.75e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMGCA_00264	1.68e-312	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKLHMGCA_00265	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKLHMGCA_00266	1.01e-158	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_00269	1.73e-67	-	-	-	-	-	-	-	-
HKLHMGCA_00270	4.78e-65	-	-	-	-	-	-	-	-
HKLHMGCA_00271	5.28e-146	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HKLHMGCA_00272	2.04e-226	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HKLHMGCA_00273	3.13e-172	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKLHMGCA_00274	2.56e-76	-	-	-	-	-	-	-	-
HKLHMGCA_00275	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKLHMGCA_00276	8.2e-102	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKLHMGCA_00277	2.43e-150	yjcF	-	-	J	-	-	-	HAD-hyrolase-like
HKLHMGCA_00278	2.97e-210	-	-	-	G	-	-	-	Fructosamine kinase
HKLHMGCA_00279	4.01e-200	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	N-acetylmuramoyl-L-alanine amidase
HKLHMGCA_00280	2.47e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HKLHMGCA_00281	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HKLHMGCA_00282	2.61e-132	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLHMGCA_00283	4.35e-204	yitT	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHMGCA_00284	1.84e-284	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKLHMGCA_00285	1.42e-217	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKLHMGCA_00286	3.5e-164	-	-	-	C	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKLHMGCA_00287	2.32e-194	yqfL	2.7.11.33, 2.7.4.28	-	F	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKLHMGCA_00288	1.09e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HKLHMGCA_00289	9.21e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HKLHMGCA_00290	4.81e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HKLHMGCA_00291	7.7e-110	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKLHMGCA_00292	1.15e-94	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HKLHMGCA_00293	7.92e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKLHMGCA_00294	2.84e-189	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HKLHMGCA_00295	8.64e-224	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HKLHMGCA_00296	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HKLHMGCA_00297	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKLHMGCA_00298	1.74e-251	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKLHMGCA_00299	1.18e-85	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKLHMGCA_00300	4.94e-213	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00301	4.14e-190	-	-	-	-	-	-	-	-
HKLHMGCA_00302	6.08e-253	-	-	-	-	-	-	-	-
HKLHMGCA_00303	2.02e-168	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKLHMGCA_00304	6.19e-208	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00305	0.000138	yjdF	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HKLHMGCA_00306	1.28e-148	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKLHMGCA_00307	5.53e-94	-	-	-	K	-	-	-	MarR family
HKLHMGCA_00308	6.64e-109	-	-	-	K	ko:K03827	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKLHMGCA_00310	4.17e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_00311	1.27e-174	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKLHMGCA_00312	1.46e-265	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKLHMGCA_00313	1.51e-132	desR	-	-	K	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, Lux Regulon
HKLHMGCA_00314	0.0	nox4	-	-	C	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKLHMGCA_00316	3.78e-221	cryZ	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKLHMGCA_00317	5.72e-207	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_00318	1.74e-101	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2255)
HKLHMGCA_00319	1.39e-143	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_00320	7.24e-204	-	-	-	S	-	-	-	Alpha beta hydrolase
HKLHMGCA_00321	2.49e-167	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKLHMGCA_00322	2.31e-132	thgA3	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKLHMGCA_00323	1.77e-145	-	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	haloacid dehalogenase-like hydrolase
HKLHMGCA_00325	1.31e-29	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_00326	8.13e-90	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_00327	2.15e-07	-	-	-	K	-	-	-	transcriptional regulator
HKLHMGCA_00328	5.58e-274	-	-	-	S	-	-	-	membrane
HKLHMGCA_00329	1.51e-105	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00330	0.0	-	-	-	S	-	-	-	Zinc finger, swim domain protein
HKLHMGCA_00331	8.09e-146	-	-	-	GM	-	-	-	epimerase
HKLHMGCA_00332	6.34e-90	-	-	-	S	-	-	-	Protein of unknown function (DUF1722)
HKLHMGCA_00333	2.65e-93	spx2	-	-	P	ko:K16509	-	ko00000	ArsC family
HKLHMGCA_00334	1.4e-137	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	NUDIX domain
HKLHMGCA_00335	1.68e-176	-	-	-	K	ko:K22103	-	ko00000,ko03000	DeoR C terminal sensor domain
HKLHMGCA_00336	1.64e-126	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKLHMGCA_00337	4.68e-244	nox	-	-	P	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKLHMGCA_00338	7.53e-264	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKLHMGCA_00339	4.38e-102	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_00340	1.32e-306	-	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Major Facilitator Superfamily
HKLHMGCA_00341	1.04e-308	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKLHMGCA_00342	5.65e-174	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKLHMGCA_00343	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKLHMGCA_00344	1.02e-230	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKLHMGCA_00345	4.8e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HKLHMGCA_00346	1.93e-266	-	-	-	-	-	-	-	-
HKLHMGCA_00347	6.11e-118	yetL	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_00348	1.06e-69	-	-	-	P	-	-	-	Rhodanese Homology Domain
HKLHMGCA_00349	0.0	pps	2.7.9.2	-	H	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HKLHMGCA_00350	2.74e-112	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_00351	2.08e-213	drrA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_00352	5.09e-165	drrB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 type transporter
HKLHMGCA_00353	1.75e-295	-	-	-	M	-	-	-	O-Antigen ligase
HKLHMGCA_00354	6.85e-164	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HKLHMGCA_00355	1.09e-249	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKLHMGCA_00356	3.17e-299	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HKLHMGCA_00357	0.0	clpB	-	-	O	ko:K03695	ko04213,map04213	ko00000,ko00001,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKLHMGCA_00359	1.37e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKLHMGCA_00360	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HKLHMGCA_00361	8.69e-230	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKLHMGCA_00362	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HKLHMGCA_00363	2.51e-98	ytwI	-	-	S	-	-	-	Protein of unknown function (DUF441)
HKLHMGCA_00364	7.94e-218	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HKLHMGCA_00365	3.13e-211	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HKLHMGCA_00366	3.99e-92	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKLHMGCA_00367	7.1e-176	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKLHMGCA_00368	1.3e-132	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKLHMGCA_00369	2.69e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKLHMGCA_00370	2.24e-126	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKLHMGCA_00371	1.72e-245	-	-	-	S	-	-	-	Helix-turn-helix domain
HKLHMGCA_00372	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKLHMGCA_00373	1.25e-39	-	-	-	M	-	-	-	Lysin motif
HKLHMGCA_00374	1.27e-151	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HKLHMGCA_00375	9.4e-280	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HKLHMGCA_00376	4.84e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HKLHMGCA_00377	5.57e-55	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKLHMGCA_00378	7.1e-292	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HKLHMGCA_00379	7.48e-192	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKLHMGCA_00380	1.39e-185	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKLHMGCA_00381	1.27e-291	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKLHMGCA_00382	6.46e-109	-	-	-	-	-	-	-	-
HKLHMGCA_00383	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00384	4.04e-242	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKLHMGCA_00385	1.8e-119	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKLHMGCA_00386	2.03e-189	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKLHMGCA_00387	5.66e-207	XK27_03630	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HKLHMGCA_00388	3.29e-147	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HKLHMGCA_00389	9.33e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HKLHMGCA_00390	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HKLHMGCA_00391	0.0	qacA	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_00392	1.43e-251	XK27_00915	-	-	C	-	-	-	Luciferase-like monooxygenase
HKLHMGCA_00393	3.53e-160	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKLHMGCA_00394	1.27e-222	-	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HKLHMGCA_00395	7.05e-219	cpsY	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKLHMGCA_00396	5.13e-292	XK27_05470	-	-	E	-	-	-	Methionine synthase
HKLHMGCA_00398	2.25e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKLHMGCA_00399	1.01e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLHMGCA_00400	8.11e-203	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HKLHMGCA_00401	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKLHMGCA_00402	0.0	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKLHMGCA_00403	1.5e-227	xerC	-	-	D	ko:K03733,ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family. XerC subfamily
HKLHMGCA_00404	6.84e-121	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKLHMGCA_00405	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKLHMGCA_00406	1.27e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HKLHMGCA_00407	2.4e-137	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKLHMGCA_00408	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLHMGCA_00409	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKLHMGCA_00410	5.43e-228	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_00411	3.21e-215	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HKLHMGCA_00412	3.8e-105	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HKLHMGCA_00413	9.17e-126	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLHMGCA_00414	1.07e-43	-	-	-	S	-	-	-	YozE SAM-like fold
HKLHMGCA_00415	4.19e-203	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HKLHMGCA_00416	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKLHMGCA_00417	1.18e-310	-	-	-	M	-	-	-	Glycosyl transferase family group 2
HKLHMGCA_00418	3.22e-87	-	-	-	-	-	-	-	-
HKLHMGCA_00419	0.0	gshR1	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKLHMGCA_00420	1.48e-98	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_00421	3.29e-121	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKLHMGCA_00422	0.0	tarL	2.7.8.14, 2.7.8.47	-	H	ko:K18704	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKLHMGCA_00423	2.89e-273	tarK	2.7.8.14, 2.7.8.46, 2.7.8.47	-	H	ko:K18704,ko:K21592	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKLHMGCA_00424	1.17e-181	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKLHMGCA_00425	8.6e-31	tarJ	1.1.1.137, 1.1.1.405	-	E	ko:K05352,ko:K21680	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HKLHMGCA_00426	2.13e-151	tarI	2.7.7.40, 2.7.7.60	-	I	ko:K00991,ko:K21030	ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HKLHMGCA_00427	8.23e-291	-	-	-	-	-	-	-	-
HKLHMGCA_00428	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HKLHMGCA_00429	7.79e-78	-	-	-	-	-	-	-	-
HKLHMGCA_00430	2.79e-181	-	-	-	-	-	-	-	-
HKLHMGCA_00431	7.45e-313	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKLHMGCA_00432	1.05e-176	XK27_00890	-	-	S	ko:K08974	-	ko00000	Domain of unknown function (DUF368)
HKLHMGCA_00433	9.3e-167	yejC	-	-	S	-	-	-	Protein of unknown function (DUF1003)
HKLHMGCA_00434	1.33e-67	XK27_08430	-	-	S	-	-	-	Staphylococcal protein of unknown function (DUF960)
HKLHMGCA_00436	6e-268	pmrB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKLHMGCA_00437	4.87e-191	-	-	-	C	-	-	-	Domain of unknown function (DUF4931)
HKLHMGCA_00438	2.37e-65	-	-	-	-	-	-	-	-
HKLHMGCA_00439	2.29e-36	-	-	-	-	-	-	-	-
HKLHMGCA_00440	1.96e-168	-	-	-	S	-	-	-	Protein of unknown function (DUF975)
HKLHMGCA_00441	2.47e-101	yjcF	3.5.4.33, 4.4.1.8	-	K	ko:K02348,ko:K11991,ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007,ko03016	protein acetylation
HKLHMGCA_00442	1.11e-205	-	-	-	S	-	-	-	EDD domain protein, DegV family
HKLHMGCA_00443	8.03e-87	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_00444	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKLHMGCA_00445	4.74e-208	-	-	-	S	-	-	-	Putative esterase
HKLHMGCA_00446	3.53e-169	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_00447	6.74e-117	ybaK	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKLHMGCA_00448	1.74e-178	-	-	-	-	-	-	-	-
HKLHMGCA_00449	4.85e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHMGCA_00450	8.05e-179	rrp8	-	-	K	-	-	-	LytTr DNA-binding domain
HKLHMGCA_00451	1.7e-118	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKLHMGCA_00452	1.55e-79	-	-	-	-	-	-	-	-
HKLHMGCA_00453	2.61e-96	hsp2	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKLHMGCA_00454	2.97e-76	-	-	-	-	-	-	-	-
HKLHMGCA_00455	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HKLHMGCA_00456	1.18e-114	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HKLHMGCA_00457	0.0	nhaP3	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKLHMGCA_00458	2.03e-271	yttB	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_00459	4.71e-81	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_00460	1.27e-219	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKLHMGCA_00461	4.71e-74	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKLHMGCA_00462	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKLHMGCA_00463	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	Bacterial regulatory proteins, gntR family
HKLHMGCA_00464	1.02e-277	araT2	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKLHMGCA_00465	1.21e-183	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKLHMGCA_00466	3.59e-26	-	-	-	-	-	-	-	-
HKLHMGCA_00467	2.09e-169	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKLHMGCA_00468	5.73e-208	mleR	-	-	K	-	-	-	LysR family
HKLHMGCA_00469	1.29e-148	-	-	-	GM	-	-	-	NAD(P)H-binding
HKLHMGCA_00470	3.86e-124	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKLHMGCA_00471	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HKLHMGCA_00472	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HKLHMGCA_00473	9.44e-219	oroP	-	-	S	ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Putative inner membrane exporter, YdcZ
HKLHMGCA_00474	6.64e-146	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKLHMGCA_00475	1.55e-161	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKLHMGCA_00476	1.04e-218	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKLHMGCA_00477	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKLHMGCA_00478	2.76e-271	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKLHMGCA_00479	2.38e-310	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKLHMGCA_00480	1.22e-220	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HKLHMGCA_00481	7.13e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKLHMGCA_00482	0.0	pucR_2	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
HKLHMGCA_00483	3.1e-305	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HKLHMGCA_00484	5.67e-280	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	Permease family
HKLHMGCA_00485	2.24e-206	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_00486	1.25e-199	-	-	-	T	-	-	-	EAL domain
HKLHMGCA_00487	3.73e-121	-	-	-	-	-	-	-	-
HKLHMGCA_00488	0.0	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKLHMGCA_00489	6.93e-162	-	-	-	E	-	-	-	Methionine synthase
HKLHMGCA_00490	9.06e-279	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HKLHMGCA_00491	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HKLHMGCA_00492	5.35e-133	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKLHMGCA_00493	2.97e-243	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HKLHMGCA_00494	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKLHMGCA_00495	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHMGCA_00496	1.63e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHMGCA_00497	1.17e-55	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKLHMGCA_00498	3.39e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HKLHMGCA_00499	5.8e-270	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKLHMGCA_00500	3.77e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKLHMGCA_00501	7.9e-305	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
HKLHMGCA_00502	9.92e-143	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKLHMGCA_00503	2.01e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HKLHMGCA_00504	2.04e-189	ptp3	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKLHMGCA_00505	3.44e-152	cah	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HKLHMGCA_00506	4.15e-191	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_00507	3.7e-233	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	Asparaginase
HKLHMGCA_00508	8.34e-178	cysA	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00509	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKLHMGCA_00510	4.76e-56	-	-	-	-	-	-	-	-
HKLHMGCA_00511	8.2e-81	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HKLHMGCA_00512	7.89e-212	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00513	3.41e-190	-	-	-	-	-	-	-	-
HKLHMGCA_00514	2.7e-104	usp5	-	-	T	-	-	-	universal stress protein
HKLHMGCA_00515	1.08e-47	-	-	-	-	-	-	-	-
HKLHMGCA_00516	4.02e-95	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKLHMGCA_00517	1.76e-114	-	-	-	-	-	-	-	-
HKLHMGCA_00518	4.87e-66	-	-	-	-	-	-	-	-
HKLHMGCA_00519	4.79e-13	-	-	-	-	-	-	-	-
HKLHMGCA_00520	8.32e-297	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKLHMGCA_00521	1.16e-110	-	-	-	F	-	-	-	belongs to the nudix hydrolase family
HKLHMGCA_00522	1.02e-149	-	-	-	-	-	-	-	-
HKLHMGCA_00523	1.21e-69	-	-	-	-	-	-	-	-
HKLHMGCA_00524	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKLHMGCA_00525	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HKLHMGCA_00526	1.33e-185	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKLHMGCA_00527	4.72e-40	-	-	-	S	-	-	-	Pentapeptide repeats (8 copies)
HKLHMGCA_00528	3.55e-143	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKLHMGCA_00529	3.24e-132	-	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HKLHMGCA_00530	2.26e-91	-	-	-	FG	-	-	-	Scavenger mRNA decapping enzyme C-term binding
HKLHMGCA_00531	1.62e-173	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKLHMGCA_00532	3.94e-49	XK27_01315	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HKLHMGCA_00533	9.97e-269	ybhE	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKLHMGCA_00534	3.64e-293	-	-	-	S	-	-	-	Sterol carrier protein domain
HKLHMGCA_00535	3.26e-262	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HKLHMGCA_00536	7.54e-115	yrxA	-	-	S	ko:K07105	-	ko00000	3H domain
HKLHMGCA_00537	2.97e-68	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKLHMGCA_00538	2.44e-42	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKLHMGCA_00540	3.13e-99	-	-	-	L	-	-	-	Transposase DDE domain
HKLHMGCA_00541	3.33e-89	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKLHMGCA_00542	2.23e-40	-	-	-	-	-	-	-	-
HKLHMGCA_00543	9.82e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HKLHMGCA_00544	9.56e-89	-	-	-	S	-	-	-	Phage regulatory protein Rha (Phage_pRha)
HKLHMGCA_00545	1.63e-187	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HKLHMGCA_00546	1.6e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKLHMGCA_00547	1.19e-201	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKLHMGCA_00548	6.87e-50	veg	-	-	S	-	-	-	Biofilm formation stimulator VEG
HKLHMGCA_00549	2.26e-209	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKLHMGCA_00550	1.9e-230	-	-	-	S	ko:K06889	-	ko00000	Prolyl oligopeptidase family
HKLHMGCA_00551	8.05e-166	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKLHMGCA_00552	6.39e-169	znuB	-	-	U	ko:K02075,ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKLHMGCA_00553	2.95e-57	-	-	-	S	-	-	-	ankyrin repeats
HKLHMGCA_00554	5.3e-49	-	-	-	-	-	-	-	-
HKLHMGCA_00555	1.96e-189	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HKLHMGCA_00556	5.78e-292	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKLHMGCA_00557	2.13e-191	bla1	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKLHMGCA_00558	3.26e-228	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKLHMGCA_00559	2.82e-236	-	-	-	S	-	-	-	DUF218 domain
HKLHMGCA_00560	2.49e-178	-	-	-	-	-	-	-	-
HKLHMGCA_00561	1.45e-191	yxeH	-	-	S	-	-	-	hydrolase
HKLHMGCA_00562	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HKLHMGCA_00563	6.05e-198	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	biotin lipoate A B protein ligase
HKLHMGCA_00564	2.87e-101	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HKLHMGCA_00565	2.96e-89	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKLHMGCA_00566	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKLHMGCA_00567	8.29e-312	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKLHMGCA_00568	2.28e-290	sdaC	-	-	E	ko:K03837	-	ko00000,ko02000	amino acid
HKLHMGCA_00569	7.51e-159	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HKLHMGCA_00570	2.31e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HKLHMGCA_00571	1.55e-168	-	-	-	S	-	-	-	YheO-like PAS domain
HKLHMGCA_00572	4.01e-36	-	-	-	-	-	-	-	-
HKLHMGCA_00573	2.08e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLHMGCA_00574	6.26e-306	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKLHMGCA_00575	1.91e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HKLHMGCA_00576	1.49e-273	-	-	-	J	-	-	-	translation release factor activity
HKLHMGCA_00577	3.14e-164	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HKLHMGCA_00578	5.35e-121	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HKLHMGCA_00579	1.78e-191	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HKLHMGCA_00580	1.84e-189	-	-	-	-	-	-	-	-
HKLHMGCA_00581	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKLHMGCA_00582	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKLHMGCA_00583	9.32e-81	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKLHMGCA_00584	5e-275	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKLHMGCA_00585	2.58e-85	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKLHMGCA_00586	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKLHMGCA_00587	1.13e-247	-	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_00588	7.44e-203	-	-	-	U	ko:K02050	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_00589	2.02e-171	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKLHMGCA_00590	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKLHMGCA_00591	2.61e-260	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HKLHMGCA_00592	3.61e-244	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKLHMGCA_00593	3.39e-294	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKLHMGCA_00594	2.36e-166	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HKLHMGCA_00595	4.28e-274	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HKLHMGCA_00596	2.63e-241	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKLHMGCA_00597	1.3e-110	queT	-	-	S	-	-	-	QueT transporter
HKLHMGCA_00598	5.29e-211	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKLHMGCA_00599	8.1e-157	pepL	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKLHMGCA_00600	4.87e-148	-	-	-	S	-	-	-	(CBS) domain
HKLHMGCA_00601	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HKLHMGCA_00602	1.61e-225	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKLHMGCA_00603	1.43e-129	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKLHMGCA_00604	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKLHMGCA_00605	0.0	yabM	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKLHMGCA_00606	7.72e-57	yabO	-	-	J	-	-	-	S4 domain protein
HKLHMGCA_00608	2.02e-83	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HKLHMGCA_00609	1.07e-103	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HKLHMGCA_00610	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKLHMGCA_00611	4.3e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HKLHMGCA_00612	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKLHMGCA_00613	1.93e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKLHMGCA_00614	5.33e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLHMGCA_00615	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HKLHMGCA_00616	2.83e-58	-	-	-	L	ko:K07473	-	ko00000,ko02048	Addiction module antitoxin, RelB DinJ family
HKLHMGCA_00617	1.91e-49	-	-	-	M	-	-	-	LysM domain protein
HKLHMGCA_00618	5.22e-19	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKLHMGCA_00619	9.04e-155	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKLHMGCA_00620	5.42e-142	-	-	-	GK	-	-	-	ROK family
HKLHMGCA_00621	3.26e-293	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKLHMGCA_00622	2.42e-238	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKLHMGCA_00623	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HKLHMGCA_00624	1.07e-213	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HKLHMGCA_00625	4.94e-197	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKLHMGCA_00626	1.94e-149	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKLHMGCA_00627	6.75e-157	-	-	-	-	-	-	-	-
HKLHMGCA_00628	2.78e-273	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKLHMGCA_00629	0.0	mdr	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_00630	9.73e-50	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HKLHMGCA_00631	1.09e-256	-	-	-	N	-	-	-	Cell shape-determining protein MreB
HKLHMGCA_00632	0.0	-	-	-	S	-	-	-	Pfam Methyltransferase
HKLHMGCA_00633	0.0	tagE2	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKLHMGCA_00634	0.0	tagE3	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKLHMGCA_00635	9.32e-40	-	-	-	-	-	-	-	-
HKLHMGCA_00636	3.03e-122	mraW1	-	-	J	-	-	-	Putative rRNA methylase
HKLHMGCA_00637	2.95e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HKLHMGCA_00638	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHMGCA_00639	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HKLHMGCA_00640	5.04e-176	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HKLHMGCA_00641	3.03e-193	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKLHMGCA_00642	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HKLHMGCA_00643	9.54e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKLHMGCA_00644	1.45e-258	ugpC	3.6.3.20	-	E	ko:K05816,ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the ABC transporter superfamily
HKLHMGCA_00645	3.93e-222	ugpA	-	-	U	ko:K02025,ko:K05814	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_00646	6.16e-193	ugpE	-	-	G	ko:K05815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_00647	0.0	ugpB	-	-	G	ko:K05813	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKLHMGCA_00648	5.45e-162	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HKLHMGCA_00649	2.07e-155	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKLHMGCA_00650	3.55e-72	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKLHMGCA_00651	1.48e-315	XK27_06930	-	-	V	ko:K01421	-	ko00000	domain protein
HKLHMGCA_00653	3.03e-135	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	Transport permease protein
HKLHMGCA_00654	3.06e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_00655	2.57e-226	-	-	-	K	ko:K01990	-	ko00000,ko00002,ko02000	LytTr DNA-binding domain
HKLHMGCA_00657	6.96e-198	mrsA1	1.8.4.11	-	O	ko:K07304	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKLHMGCA_00658	5.2e-85	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_00659	1.91e-150	-	-	-	GM	-	-	-	NAD(P)H-binding
HKLHMGCA_00660	9.36e-205	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKLHMGCA_00661	1.14e-190	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKLHMGCA_00662	7.83e-140	-	-	-	-	-	-	-	-
HKLHMGCA_00663	8.83e-285	pltK	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKLHMGCA_00664	9.01e-179	agrA	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKLHMGCA_00665	5.37e-74	-	-	-	-	-	-	-	-
HKLHMGCA_00666	4.56e-78	-	-	-	-	-	-	-	-
HKLHMGCA_00667	3.54e-145	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_00668	2.2e-111	ohrR	-	-	K	ko:K18906	-	ko00000,ko00002,ko01504,ko03000	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_00669	2.95e-117	-	-	-	-	-	-	-	-
HKLHMGCA_00670	7.12e-62	-	-	-	-	-	-	-	-
HKLHMGCA_00671	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HKLHMGCA_00674	4.29e-87	-	-	-	-	-	-	-	-
HKLHMGCA_00675	9.03e-16	-	-	-	-	-	-	-	-
HKLHMGCA_00676	1.12e-236	-	-	-	-	-	-	-	-
HKLHMGCA_00677	4.91e-117	gtcA1	-	-	S	-	-	-	Teichoic acid glycosylation protein
HKLHMGCA_00678	8.01e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1516)
HKLHMGCA_00679	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKLHMGCA_00680	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKLHMGCA_00681	0.0	-	-	-	S	-	-	-	Protein conserved in bacteria
HKLHMGCA_00682	2.98e-291	sat	2.7.7.4	-	H	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HKLHMGCA_00683	3.72e-145	cysC	2.7.1.25	-	F	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HKLHMGCA_00684	2.54e-225	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain
HKLHMGCA_00685	0.0	astA	2.8.2.22	-	M	ko:K01023	-	ko00000,ko01000	Arylsulfotransferase Ig-like domain
HKLHMGCA_00686	0.0	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HKLHMGCA_00687	1.51e-48	-	-	-	-	-	-	-	-
HKLHMGCA_00688	5.79e-21	-	-	-	-	-	-	-	-
HKLHMGCA_00689	2.22e-55	-	-	-	S	-	-	-	transglycosylase associated protein
HKLHMGCA_00690	4e-40	-	-	-	S	-	-	-	CsbD-like
HKLHMGCA_00691	1.06e-53	-	-	-	-	-	-	-	-
HKLHMGCA_00692	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKLHMGCA_00693	8.39e-38	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HKLHMGCA_00694	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKLHMGCA_00695	1.48e-218	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HKLHMGCA_00696	5.03e-182	-	-	-	U	ko:K10716	-	ko00000,ko02000	Ion channel
HKLHMGCA_00697	1.25e-66	-	-	-	-	-	-	-	-
HKLHMGCA_00698	3.23e-58	-	-	-	-	-	-	-	-
HKLHMGCA_00699	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKLHMGCA_00700	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKLHMGCA_00701	3.86e-192	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKLHMGCA_00702	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HKLHMGCA_00703	1.38e-156	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKLHMGCA_00704	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKLHMGCA_00705	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKLHMGCA_00706	3.36e-247	galM2	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKLHMGCA_00707	8.61e-251	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKLHMGCA_00708	1.77e-262	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HKLHMGCA_00709	1.1e-230	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HKLHMGCA_00710	1.48e-217	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HKLHMGCA_00711	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HKLHMGCA_00712	2.53e-107	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HKLHMGCA_00713	3.1e-289	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HKLHMGCA_00714	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKLHMGCA_00715	3.25e-165	dnaD	-	-	L	ko:K02086	-	ko00000	Replication initiation and membrane attachment
HKLHMGCA_00717	1.34e-237	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKLHMGCA_00718	2.45e-142	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_00719	1.58e-203	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKLHMGCA_00720	5.32e-109	-	-	-	T	-	-	-	Universal stress protein family
HKLHMGCA_00721	0.0	ftpA	-	-	P	ko:K02011	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_00722	8.06e-234	ftpB	-	-	P	ko:K02012	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKLHMGCA_00723	8.03e-229	phnT	3.6.3.30	-	P	ko:K02010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HKLHMGCA_00724	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HKLHMGCA_00725	3.6e-152	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKLHMGCA_00726	2.12e-142	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HKLHMGCA_00727	9.98e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKLHMGCA_00729	1.44e-282	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HKLHMGCA_00730	1.26e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_00731	1.55e-309	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKLHMGCA_00732	4.17e-186	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HKLHMGCA_00733	9.19e-95	-	-	-	S	-	-	-	SnoaL-like domain
HKLHMGCA_00734	9.63e-307	-	-	-	M	-	-	-	Glycosyltransferase, group 2 family protein
HKLHMGCA_00735	3.46e-267	mccF	-	-	V	-	-	-	LD-carboxypeptidase
HKLHMGCA_00736	2.75e-100	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_00737	1.23e-311	-	-	-	M	ko:K07273	-	ko00000	hydrolase, family 25
HKLHMGCA_00738	1.38e-232	-	-	-	V	-	-	-	LD-carboxypeptidase
HKLHMGCA_00739	4.35e-159	-	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKLHMGCA_00740	1.9e-156	-	-	-	P	ko:K01990	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKLHMGCA_00741	6.79e-249	-	-	-	-	-	-	-	-
HKLHMGCA_00742	3.03e-186	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HKLHMGCA_00743	8.53e-268	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	FAD dependent oxidoreductase
HKLHMGCA_00744	3.28e-87	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HKLHMGCA_00745	5.04e-82	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HKLHMGCA_00746	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HKLHMGCA_00747	1.65e-97	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKLHMGCA_00748	9.72e-225	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKLHMGCA_00749	1.9e-115	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKLHMGCA_00750	1.71e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HKLHMGCA_00751	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HKLHMGCA_00752	2.01e-145	-	-	-	G	-	-	-	Phosphoglycerate mutase family
HKLHMGCA_00753	7.75e-93	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HKLHMGCA_00755	2.24e-167	cat	2.3.1.28	-	V	ko:K19271	-	br01600,ko00000,ko01000,ko01504	Chloramphenicol acetyltransferase
HKLHMGCA_00756	2.08e-92	-	-	-	S	-	-	-	LuxR family transcriptional regulator
HKLHMGCA_00757	3.42e-176	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2087)
HKLHMGCA_00759	1.27e-115	-	-	-	F	-	-	-	NUDIX domain
HKLHMGCA_00760	4.87e-205	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00761	9.28e-171	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKLHMGCA_00762	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HKLHMGCA_00763	0.0	aapA	-	-	M	-	-	-	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HKLHMGCA_00764	2.81e-181	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_00765	1.47e-51	-	-	-	S	ko:K07343	-	ko00000	TfoX C-terminal domain
HKLHMGCA_00766	3.05e-289	hpk9	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKLHMGCA_00767	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_00768	2.69e-99	-	-	-	-	-	-	-	-
HKLHMGCA_00769	5.14e-246	-	-	-	S	-	-	-	Cell surface protein
HKLHMGCA_00770	3.48e-136	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00771	1.55e-224	-	-	-	C	-	-	-	Alcohol dehydrogenase GroES-like domain
HKLHMGCA_00772	1.27e-90	-	-	-	S	-	-	-	Iron-sulphur cluster biosynthesis
HKLHMGCA_00773	3.89e-148	-	-	-	S	-	-	-	GyrI-like small molecule binding domain
HKLHMGCA_00774	7.66e-237	ynjC	-	-	S	-	-	-	Cell surface protein
HKLHMGCA_00775	2.7e-131	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00776	1.47e-83	-	-	-	-	-	-	-	-
HKLHMGCA_00777	3.5e-302	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HKLHMGCA_00778	4.13e-157	-	-	-	-	-	-	-	-
HKLHMGCA_00779	4.31e-149	-	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKLHMGCA_00780	3.25e-81	ytcD	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKLHMGCA_00781	1.81e-272	-	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_00782	7.81e-148	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKLHMGCA_00783	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKLHMGCA_00784	1.27e-170	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKLHMGCA_00785	4.17e-281	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKLHMGCA_00787	1.03e-126	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00788	6.24e-215	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_00789	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HKLHMGCA_00790	0.0	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKLHMGCA_00791	4.41e-54	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKLHMGCA_00792	1.62e-62	-	-	-	S	-	-	-	Domain of unknown function (DUF1905)
HKLHMGCA_00793	1.27e-83	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKLHMGCA_00794	3.27e-170	-	-	-	S	-	-	-	KR domain
HKLHMGCA_00795	1.66e-125	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00796	3.47e-244	-	1.1.1.219	-	GM	ko:K00091	-	ko00000,ko01000	Male sterility protein
HKLHMGCA_00797	1.09e-130	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKLHMGCA_00798	2.21e-226	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKLHMGCA_00799	0.0	yfjF	-	-	U	-	-	-	Sugar (and other) transporter
HKLHMGCA_00800	7.57e-141	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00801	3.35e-217	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HKLHMGCA_00802	6.37e-188	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKLHMGCA_00803	1.81e-228	fhuB	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMGCA_00804	1.92e-218	fhuG	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKLHMGCA_00805	3.74e-120	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00806	7.95e-201	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_00807	2.47e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_00808	4.01e-96	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HKLHMGCA_00809	1.5e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKLHMGCA_00810	6.41e-84	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_00811	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKLHMGCA_00812	1.07e-115	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKLHMGCA_00813	3.25e-96	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKLHMGCA_00814	1.1e-115	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00815	1.6e-261	-	-	-	NU	-	-	-	Mycoplasma protein of unknown function, DUF285
HKLHMGCA_00816	6.88e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00817	0.0	lepA2	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKLHMGCA_00818	0.0	nhaP4	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKLHMGCA_00819	1.07e-200	-	3.6.1.22	-	L	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	ko00000,ko00001,ko01000	NADH pyrophosphatase zinc ribbon domain
HKLHMGCA_00820	1.06e-205	-	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_00821	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKLHMGCA_00822	0.0	-	-	-	S	-	-	-	MucBP domain
HKLHMGCA_00823	2.43e-87	gcsH1	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Glycine cleavage H-protein
HKLHMGCA_00824	2.59e-228	-	-	-	-	-	-	-	-
HKLHMGCA_00825	2.11e-104	-	-	-	-	-	-	-	-
HKLHMGCA_00826	3.47e-47	-	-	-	-	-	-	-	-
HKLHMGCA_00827	0.0	uvrB3	3.1.12.1	-	KL	ko:K07464	-	ko00000,ko01000,ko02048	DEAD_2
HKLHMGCA_00828	2.03e-75	-	-	-	-	-	-	-	-
HKLHMGCA_00829	9.17e-285	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHMGCA_00830	1.26e-100	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKLHMGCA_00831	1.24e-99	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_00832	9.59e-288	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKLHMGCA_00833	2.18e-53	-	-	-	-	-	-	-	-
HKLHMGCA_00834	3.07e-264	potD	-	-	P	ko:K11069	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_00835	1.31e-179	potC	-	-	P	ko:K11070	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_00836	3.14e-190	potB	-	-	P	ko:K11071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_00837	1.46e-262	potA	3.6.3.30, 3.6.3.31	-	P	ko:K02010,ko:K11072	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HKLHMGCA_00838	1.5e-124	-	-	-	K	-	-	-	Cupin domain
HKLHMGCA_00839	8.08e-110	-	-	-	S	-	-	-	ASCH
HKLHMGCA_00840	1.88e-111	-	-	-	K	-	-	-	GNAT family
HKLHMGCA_00841	1.19e-114	-	-	-	K	-	-	-	acetyltransferase
HKLHMGCA_00842	2.06e-30	-	-	-	-	-	-	-	-
HKLHMGCA_00843	5.05e-79	-	-	-	K	ko:K07979	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKLHMGCA_00844	7.53e-208	-	-	-	V	ko:K01990,ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_00845	1.08e-243	-	-	-	-	-	-	-	-
HKLHMGCA_00846	0.0	acdH	1.1.1.1, 1.2.1.10, 1.2.1.87	-	C	ko:K04072,ko:K13922	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00640,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00640,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Aldehyde dehydrogenase family
HKLHMGCA_00847	8.16e-207	fba	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Fructose-1,6-bisphosphate aldolase, class II
HKLHMGCA_00849	5.55e-304	xylP1	-	-	G	-	-	-	MFS/sugar transport protein
HKLHMGCA_00850	1.43e-170	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HKLHMGCA_00851	7.28e-42	-	-	-	-	-	-	-	-
HKLHMGCA_00852	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKLHMGCA_00853	6.4e-54	-	-	-	-	-	-	-	-
HKLHMGCA_00854	4.41e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HKLHMGCA_00855	5.83e-225	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKLHMGCA_00856	4.03e-81	-	-	-	S	-	-	-	CHY zinc finger
HKLHMGCA_00857	2.58e-283	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKLHMGCA_00858	6.39e-280	-	-	-	-	-	-	-	-
HKLHMGCA_00859	8.13e-199	tagG	-	-	U	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HKLHMGCA_00860	9.42e-258	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKLHMGCA_00861	6.53e-58	-	-	-	-	-	-	-	-
HKLHMGCA_00862	4.63e-119	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKLHMGCA_00863	0.0	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKLHMGCA_00864	1.66e-305	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HKLHMGCA_00865	7.39e-226	hicD1	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKLHMGCA_00866	8.95e-60	-	-	-	-	-	-	-	-
HKLHMGCA_00867	1.05e-132	zmp1	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKLHMGCA_00868	6.87e-153	rpiA2	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HKLHMGCA_00869	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HKLHMGCA_00870	5.34e-72	-	-	-	S	ko:K08987	-	ko00000	Protein of unknown function (DUF1304)
HKLHMGCA_00871	5.33e-124	yxkA	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKLHMGCA_00872	1.96e-295	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKLHMGCA_00873	5.89e-108	-	-	-	K	-	-	-	Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HKLHMGCA_00874	2.16e-103	-	-	-	-	-	-	-	-
HKLHMGCA_00875	3.45e-103	accB3	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKLHMGCA_00876	1.49e-223	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HKLHMGCA_00877	2.42e-207	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_00878	4.06e-102	-	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA-DNA hybrid ribonuclease activity
HKLHMGCA_00879	0.0	proWX	-	-	EM	ko:K05845,ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKLHMGCA_00880	2.7e-230	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00881	0.0	gshR	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKLHMGCA_00882	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKLHMGCA_00883	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	C-terminal domain of alpha-glycerophosphate oxidase
HKLHMGCA_00884	2.14e-174	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMGCA_00885	0.0	-	-	-	M	-	-	-	domain protein
HKLHMGCA_00886	8.33e-90	-	-	-	M	-	-	-	dTDP-4-dehydrorhamnose reductase activity
HKLHMGCA_00887	1.82e-34	-	-	-	S	-	-	-	Immunity protein 74
HKLHMGCA_00888	5.01e-226	-	-	-	-	-	-	-	-
HKLHMGCA_00889	1.24e-11	-	-	-	S	-	-	-	Immunity protein 22
HKLHMGCA_00890	5.89e-131	-	-	-	S	-	-	-	ankyrin repeats
HKLHMGCA_00891	1.3e-49	-	-	-	-	-	-	-	-
HKLHMGCA_00892	8.53e-28	-	-	-	-	-	-	-	-
HKLHMGCA_00893	5.52e-64	-	-	-	U	-	-	-	nuclease activity
HKLHMGCA_00894	5.89e-90	-	-	-	-	-	-	-	-
HKLHMGCA_00895	1.32e-29	-	-	-	-	-	-	-	-
HKLHMGCA_00897	5.87e-22	-	-	-	-	-	-	-	-
HKLHMGCA_00898	3.27e-81	-	-	-	-	-	-	-	-
HKLHMGCA_00899	4.67e-250	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HKLHMGCA_00900	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKLHMGCA_00901	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HKLHMGCA_00902	1.95e-140	aqpZ	-	-	U	ko:K06188	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMGCA_00903	3.31e-282	-	-	-	S	-	-	-	associated with various cellular activities
HKLHMGCA_00904	4.67e-316	-	-	-	S	-	-	-	Putative metallopeptidase domain
HKLHMGCA_00905	1.03e-65	-	-	-	-	-	-	-	-
HKLHMGCA_00906	8.19e-134	yezE	-	-	K	ko:K16137	-	ko00000,ko03000	Bacterial regulatory proteins, tetR family
HKLHMGCA_00907	7.83e-60	-	-	-	-	-	-	-	-
HKLHMGCA_00908	4.23e-129	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00909	8.67e-160	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00910	1.83e-235	-	-	-	S	-	-	-	Cell surface protein
HKLHMGCA_00911	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKLHMGCA_00912	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HKLHMGCA_00913	5.23e-107	yoaA	-	-	J	-	-	-	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HKLHMGCA_00914	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HKLHMGCA_00915	1.82e-152	rcfA	-	-	K	ko:K21562	-	ko00000,ko03000	Transcriptional regulator, Crp Fnr family
HKLHMGCA_00916	2.98e-44	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HKLHMGCA_00917	1.74e-125	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HKLHMGCA_00918	1.01e-26	-	-	-	-	-	-	-	-
HKLHMGCA_00919	4.82e-55	yrkD	-	-	S	-	-	-	Metal-sensitive transcriptional repressor
HKLHMGCA_00920	2.34e-72	trxA3	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Thioredoxin-like domain
HKLHMGCA_00921	2.71e-182	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMGCA_00922	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HKLHMGCA_00923	1.98e-232	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKLHMGCA_00924	1.5e-165	-	-	-	S	-	-	-	Gram-negative-bacterium-type cell wall biogenesis
HKLHMGCA_00925	3.42e-174	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKLHMGCA_00926	2.07e-154	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HKLHMGCA_00927	7.46e-35	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HKLHMGCA_00928	1.12e-134	-	-	-	K	-	-	-	transcriptional regulator
HKLHMGCA_00930	9.39e-84	-	-	-	-	-	-	-	-
HKLHMGCA_00932	5.77e-81	-	-	-	-	-	-	-	-
HKLHMGCA_00933	6.18e-71	-	-	-	-	-	-	-	-
HKLHMGCA_00934	2.75e-96	-	-	-	M	-	-	-	PFAM NLP P60 protein
HKLHMGCA_00935	0.0	gadB	4.1.1.15, 4.1.2.27	-	E	ko:K01580,ko:K01634	ko00250,ko00410,ko00430,ko00600,ko00650,ko01100,ko01110,ko01120,ko02024,ko04071,ko04727,ko04940,map00250,map00410,map00430,map00600,map00650,map01100,map01110,map01120,map02024,map04071,map04727,map04940	ko00000,ko00001,ko00002,ko01000	Belongs to the group II decarboxylase family
HKLHMGCA_00936	4.45e-38	-	-	-	-	-	-	-	-
HKLHMGCA_00937	0.0	pckA	4.1.1.49	-	H	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Phosphoenolpyruvate carboxykinase
HKLHMGCA_00938	3.81e-150	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_00939	5.33e-114	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKLHMGCA_00940	2.74e-175	yesN	-	-	T	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HKLHMGCA_00941	5.48e-171	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_00942	6.48e-244	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKLHMGCA_00943	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_00944	1.39e-211	-	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HKLHMGCA_00945	1.58e-66	-	-	-	-	-	-	-	-
HKLHMGCA_00946	6.47e-124	-	-	-	K	ko:K22041	-	ko00000,ko03000	transcriptional regulator
HKLHMGCA_00947	5.94e-118	ymdB	-	-	S	-	-	-	Macro domain protein
HKLHMGCA_00948	2.69e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKLHMGCA_00949	1.5e-56	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKLHMGCA_00950	1.7e-101	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKLHMGCA_00951	2.57e-171	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKLHMGCA_00952	9.19e-208	yvgN	-	-	C	-	-	-	Aldo keto reductase
HKLHMGCA_00954	8.84e-182	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKLHMGCA_00955	0.0	yfkN	3.1.3.6, 3.1.4.16	-	F	ko:K01119	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKLHMGCA_00956	0.0	pacL3	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	Cation transporter/ATPase, N-terminus
HKLHMGCA_00957	1.14e-110	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HKLHMGCA_00958	6.1e-101	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HKLHMGCA_00959	5.99e-231	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKLHMGCA_00960	1.03e-281	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKLHMGCA_00961	1.4e-286	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_00964	5.94e-40	-	-	-	-	-	-	-	-
HKLHMGCA_00965	3.37e-141	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKLHMGCA_00966	5.93e-73	-	-	-	S	-	-	-	branched-chain amino acid
HKLHMGCA_00967	4.83e-166	-	-	-	E	-	-	-	branched-chain amino acid
HKLHMGCA_00968	6.77e-116	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HKLHMGCA_00969	7.28e-303	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKLHMGCA_00970	5.61e-273	hpk31	-	-	T	-	-	-	Histidine kinase
HKLHMGCA_00971	1.14e-159	vanR	-	-	K	-	-	-	response regulator
HKLHMGCA_00972	1.39e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HKLHMGCA_00973	3.3e-208	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKLHMGCA_00974	3.49e-270	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKLHMGCA_00975	3.49e-160	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HKLHMGCA_00976	6.6e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKLHMGCA_00977	1.4e-40	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HKLHMGCA_00978	7.16e-201	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKLHMGCA_00979	1.01e-175	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	Sporulation initiation inhibitor
HKLHMGCA_00980	8.63e-191	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HKLHMGCA_00981	1.81e-168	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HKLHMGCA_00982	1.66e-288	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Nucleoside
HKLHMGCA_00983	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKLHMGCA_00984	1.49e-188	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_00985	3.36e-216	-	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_00986	2.07e-302	-	-	-	EK	-	-	-	Aminotransferase, class I
HKLHMGCA_00987	2.13e-167	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKLHMGCA_00988	2.11e-158	tcyB	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_00989	3.02e-176	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_00990	1.26e-161	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HKLHMGCA_00991	1.07e-127	-	-	-	KT	-	-	-	response to antibiotic
HKLHMGCA_00992	2.86e-68	-	-	-	K	ko:K10947	-	ko00000,ko03000	Transcriptional regulator
HKLHMGCA_00993	1.73e-132	-	-	-	S	-	-	-	Protein of unknown function (DUF1700)
HKLHMGCA_00994	1.13e-200	-	-	-	S	-	-	-	Putative adhesin
HKLHMGCA_00995	0.0	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_00996	6.31e-64	pts26BCA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_00997	0.0	malL	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKLHMGCA_00998	6.12e-232	purR2	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HKLHMGCA_00999	3.73e-263	-	-	-	S	-	-	-	DUF218 domain
HKLHMGCA_01000	2.44e-165	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HKLHMGCA_01001	2.93e-151	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_01002	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLHMGCA_01003	6.26e-101	-	-	-	-	-	-	-	-
HKLHMGCA_01004	2.69e-194	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HKLHMGCA_01005	3.54e-190	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKLHMGCA_01006	2.24e-116	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKLHMGCA_01007	0.0	mngB	3.2.1.170	GH38	G	ko:K15524	-	ko00000,ko01000	Glycosyl hydrolases family 38 N-terminal domain
HKLHMGCA_01008	6.69e-155	fptC	-	-	U	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase system, EIIC
HKLHMGCA_01009	2.52e-35	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKLHMGCA_01010	5.55e-22	-	-	-	G	ko:K11203	-	ko00000,ko00002,ko02000	PTS system, fructose subfamily
HKLHMGCA_01011	2.11e-104	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHMGCA_01012	4.08e-101	-	-	-	K	-	-	-	MerR family regulatory protein
HKLHMGCA_01013	7.54e-200	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_01014	0.0	pts28ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_01015	5.08e-164	nth2	-	-	L	ko:K07457	-	ko00000	Base excision DNA repair protein, HhH-GPD family
HKLHMGCA_01017	8.66e-130	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKLHMGCA_01018	3.43e-303	-	-	-	S	-	-	-	module of peptide synthetase
HKLHMGCA_01019	1.78e-139	-	-	-	-	-	-	-	-
HKLHMGCA_01020	1.55e-114	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HKLHMGCA_01021	1.23e-53	-	-	-	S	-	-	-	Enterocin A Immunity
HKLHMGCA_01022	6.17e-71	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HKLHMGCA_01024	4.93e-170	cps3A	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HKLHMGCA_01025	3.67e-226	cps3B	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HKLHMGCA_01026	6.91e-283	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKLHMGCA_01027	5.58e-260	cps3D	-	-	-	-	-	-	-
HKLHMGCA_01028	3.98e-143	cps3E	-	-	-	-	-	-	-
HKLHMGCA_01029	2.03e-208	cps3F	-	-	-	-	-	-	-
HKLHMGCA_01030	1.75e-256	cps3H	-	-	-	-	-	-	-
HKLHMGCA_01031	5.67e-257	cps3I	-	-	G	-	-	-	Acyltransferase family
HKLHMGCA_01032	2.94e-190	cps3J	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HKLHMGCA_01033	1.71e-304	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HKLHMGCA_01034	4.83e-151	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HKLHMGCA_01035	2.59e-69	-	-	-	-	-	-	-	-
HKLHMGCA_01036	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HKLHMGCA_01037	1.17e-42	-	-	-	-	-	-	-	-
HKLHMGCA_01038	5.7e-36	-	-	-	-	-	-	-	-
HKLHMGCA_01039	3.82e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HKLHMGCA_01040	1.39e-169	-	-	-	-	-	-	-	-
HKLHMGCA_01041	3.93e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HKLHMGCA_01042	6.62e-138	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HKLHMGCA_01043	5.34e-168	lytE	-	-	M	-	-	-	NlpC/P60 family
HKLHMGCA_01044	8.01e-64	-	-	-	K	-	-	-	sequence-specific DNA binding
HKLHMGCA_01045	7.17e-39	-	-	-	S	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HKLHMGCA_01046	4.22e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKLHMGCA_01047	1.13e-257	yueF	-	-	S	-	-	-	AI-2E family transporter
HKLHMGCA_01048	3.5e-93	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKLHMGCA_01049	7.89e-290	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HKLHMGCA_01050	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HKLHMGCA_01051	4.77e-216	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HKLHMGCA_01052	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKLHMGCA_01053	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HKLHMGCA_01054	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_01055	2.12e-252	-	-	-	M	-	-	-	MucBP domain
HKLHMGCA_01056	1.36e-208	lysR5	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_01057	4.78e-171	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKLHMGCA_01058	3.85e-76	ywjH	-	-	S	-	-	-	Protein of unknown function (DUF1634)
HKLHMGCA_01059	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_01060	3.44e-210	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMGCA_01061	3.59e-241	oppC	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMGCA_01062	2.81e-257	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKLHMGCA_01063	5.67e-231	oppF	-	-	P	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKLHMGCA_01064	3.4e-85	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKLHMGCA_01065	2.5e-132	-	-	-	L	-	-	-	Integrase
HKLHMGCA_01066	0.0	clpE	-	-	O	ko:K03697	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HKLHMGCA_01067	5.6e-41	-	-	-	-	-	-	-	-
HKLHMGCA_01068	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HKLHMGCA_01069	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKLHMGCA_01070	1.41e-285	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKLHMGCA_01071	2.04e-254	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HKLHMGCA_01072	2.16e-241	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLHMGCA_01073	8.93e-290	dacA2	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HKLHMGCA_01074	5.8e-291	araT	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKLHMGCA_01075	1.56e-46	ykuJ	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HKLHMGCA_01076	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKLHMGCA_01077	9.54e-65	-	-	-	K	-	-	-	sequence-specific DNA binding
HKLHMGCA_01082	1.38e-19	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKLHMGCA_01083	2.05e-231	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKLHMGCA_01084	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKLHMGCA_01085	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKLHMGCA_01086	1.98e-122	citX	2.7.7.61	-	HI	ko:K05964	ko02020,map02020	ko00000,ko00001,ko01000	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HKLHMGCA_01087	1.25e-204	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HKLHMGCA_01088	6.5e-215	mleR	-	-	K	-	-	-	LysR family
HKLHMGCA_01089	0.0	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HKLHMGCA_01090	2.6e-212	mleP2	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HKLHMGCA_01091	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKLHMGCA_01092	4.37e-128	-	-	-	S	-	-	-	ECF transporter, substrate-specific component
HKLHMGCA_01093	6.07e-33	-	-	-	-	-	-	-	-
HKLHMGCA_01094	0.0	-	-	-	S	ko:K06889	-	ko00000	Alpha beta
HKLHMGCA_01095	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HKLHMGCA_01096	7.76e-234	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HKLHMGCA_01097	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HKLHMGCA_01098	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HKLHMGCA_01099	1.02e-121	-	-	-	S	-	-	-	L,D-transpeptidase catalytic domain
HKLHMGCA_01100	1.24e-66	-	-	-	S	-	-	-	protein conserved in bacteria
HKLHMGCA_01101	4.87e-234	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKLHMGCA_01102	4.92e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKLHMGCA_01103	3.86e-235	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKLHMGCA_01104	3.41e-146	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HKLHMGCA_01105	8.19e-134	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKLHMGCA_01106	1.13e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HKLHMGCA_01107	1.39e-279	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKLHMGCA_01108	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HKLHMGCA_01109	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKLHMGCA_01110	3.86e-262	camS	-	-	S	-	-	-	sex pheromone
HKLHMGCA_01111	5.11e-67	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLHMGCA_01112	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKLHMGCA_01113	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKLHMGCA_01114	1.59e-242	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HKLHMGCA_01115	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKLHMGCA_01116	5.56e-130	yobS	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_01117	0.0	yfgQ	-	-	P	ko:K12952	-	ko00000,ko01000	E1-E2 ATPase
HKLHMGCA_01118	2.75e-304	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01119	1.94e-213	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_01120	9.33e-195	gntR	-	-	K	-	-	-	rpiR family
HKLHMGCA_01121	1.67e-177	lys	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKLHMGCA_01122	7.34e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HKLHMGCA_01123	6.22e-43	cspP	-	-	K	ko:K03704	-	ko00000,ko03000	'Cold-shock' DNA-binding domain
HKLHMGCA_01124	1.94e-245	mocA	-	-	S	-	-	-	Oxidoreductase
HKLHMGCA_01125	5.62e-316	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HKLHMGCA_01127	3.93e-99	-	-	-	T	-	-	-	Universal stress protein family
HKLHMGCA_01128	5.45e-314	pts14C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01129	1.93e-210	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_01130	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01131	0.0	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_01132	3.72e-200	bglG4	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKLHMGCA_01133	0.0	pbg9	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01134	0.0	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01135	0.0	pts33BCA	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_01136	6.59e-75	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKLHMGCA_01137	4.12e-108	bglG5	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKLHMGCA_01138	0.0	treP	2.4.1.64	GH65	G	ko:K05342	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKLHMGCA_01139	1.08e-221	cytR	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKLHMGCA_01140	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HKLHMGCA_01141	0.0	agl	3.2.1.20	GH31	G	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 31 family
HKLHMGCA_01143	1.91e-235	cbh	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKLHMGCA_01144	7.09e-184	yxeH	-	-	S	-	-	-	hydrolase
HKLHMGCA_01145	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKLHMGCA_01146	1.02e-147	tal	2.2.1.2	-	F	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKLHMGCA_01147	1.17e-305	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKLHMGCA_01148	7.29e-61	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
HKLHMGCA_01149	1.58e-101	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHMGCA_01150	0.0	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHMGCA_01151	9.14e-146	gph3	-	-	S	-	-	-	Haloacid dehalogenase-like hydrolase
HKLHMGCA_01152	5.26e-247	-	1.1.1.14	-	C	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HKLHMGCA_01153	8.37e-296	gatC	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
HKLHMGCA_01154	6e-60	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKLHMGCA_01155	3.99e-106	-	2.7.1.200, 2.7.1.204	-	G	ko:K02773,ko:K20112	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HKLHMGCA_01156	1.83e-146	-	-	-	K	ko:K02444	-	ko00000,ko03000	DeoR C terminal sensor domain
HKLHMGCA_01157	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HKLHMGCA_01158	3.76e-180	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKLHMGCA_01159	6.47e-95	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKLHMGCA_01160	7.3e-210	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKLHMGCA_01161	3.89e-205	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKLHMGCA_01162	0.0	-	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKLHMGCA_01163	4.01e-263	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKLHMGCA_01164	9.03e-173	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKLHMGCA_01165	4.66e-197	nanK	-	-	GK	-	-	-	ROK family
HKLHMGCA_01166	1.86e-210	nanA	4.1.3.3	-	EM	ko:K01639	ko00520,map00520	ko00000,ko00001,ko01000	Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HKLHMGCA_01167	2.13e-159	nanE	5.1.3.9	-	G	ko:K01788	ko00520,map00520	ko00000,ko00001,ko01000	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HKLHMGCA_01168	2.28e-291	-	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase
HKLHMGCA_01169	2.43e-91	-	-	-	S	-	-	-	Pyrimidine dimer DNA glycosylase
HKLHMGCA_01170	2.1e-116	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKLHMGCA_01171	1.06e-16	-	-	-	-	-	-	-	-
HKLHMGCA_01172	1.96e-21	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
HKLHMGCA_01173	0.0	katA	1.11.1.6	-	C	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	Belongs to the catalase family
HKLHMGCA_01174	1.32e-101	nrp	-	-	K	ko:K16509	-	ko00000	ArsC family
HKLHMGCA_01175	7.42e-174	-	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKLHMGCA_01176	2.18e-211	blpH	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKLHMGCA_01177	9.62e-19	-	-	-	-	-	-	-	-
HKLHMGCA_01178	1.51e-85	-	-	-	KOT	ko:K07813	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01002	May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HKLHMGCA_01179	0.0	clpL	-	-	O	ko:K04086	-	ko00000,ko03110	C-terminal, D2-small domain, of ClpB protein
HKLHMGCA_01181	4.64e-255	lctO	1.13.12.4	-	C	ko:K00467,ko:K10530	ko00620,map00620	ko00000,ko00001,ko01000	L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HKLHMGCA_01182	0.0	pox4	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKLHMGCA_01183	5.03e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_01184	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKLHMGCA_01185	6.96e-83	pts38A	2.7.1.198	-	G	ko:K02781	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system glucitol/sorbitol-specific IIA component
HKLHMGCA_01186	5.88e-233	srlE	2.7.1.198	-	G	ko:K02782,ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Sorbitol phosphotransferase enzyme II N-terminus
HKLHMGCA_01187	1.23e-129	srlA	-	-	G	ko:K02783	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko02000	PTS system enzyme II sorbitol-specific factor
HKLHMGCA_01188	3.33e-113	srlM1	-	-	K	-	-	-	Glucitol operon activator protein (GutM)
HKLHMGCA_01189	0.0	srlM	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HKLHMGCA_01190	1.56e-185	srlD2	1.1.1.140	-	IQ	ko:K00068	ko00051,map00051	ko00000,ko00001,ko01000	NAD dependent epimerase/dehydratase family
HKLHMGCA_01191	2.53e-209	rbsU	-	-	U	ko:K06216	-	ko00000,ko02000	ribose uptake protein RbsU
HKLHMGCA_01192	4.99e-88	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKLHMGCA_01193	7.82e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKLHMGCA_01194	4.04e-241	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HKLHMGCA_01195	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HKLHMGCA_01196	2.51e-103	-	-	-	T	-	-	-	Universal stress protein family
HKLHMGCA_01197	7.43e-130	padR	-	-	K	-	-	-	Virulence activator alpha C-term
HKLHMGCA_01198	2.71e-135	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HKLHMGCA_01199	6.11e-187	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HKLHMGCA_01200	3.66e-113	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_01201	4.69e-202	degV1	-	-	S	-	-	-	DegV family
HKLHMGCA_01202	1.67e-79	-	-	-	K	-	-	-	Bacteriophage CI repressor helix-turn-helix domain
HKLHMGCA_01203	0.0	pepE	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	aminopeptidase
HKLHMGCA_01205	2.76e-141	sip3	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKLHMGCA_01206	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_01208	2.23e-211	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF916)
HKLHMGCA_01209	1.31e-143	-	-	-	S	-	-	-	Cell surface protein
HKLHMGCA_01210	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKLHMGCA_01211	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKLHMGCA_01212	2.26e-171	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HKLHMGCA_01213	2.26e-306	-	-	-	Q	-	-	-	Imidazolonepropionase and related amidohydrolases
HKLHMGCA_01214	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_01215	1.55e-158	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLHMGCA_01216	3.74e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HKLHMGCA_01217	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKLHMGCA_01218	8.19e-267	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKLHMGCA_01219	3.82e-51	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HKLHMGCA_01220	7.24e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKLHMGCA_01221	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLHMGCA_01222	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKLHMGCA_01223	1.71e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HKLHMGCA_01224	1.59e-95	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKLHMGCA_01225	2.69e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKLHMGCA_01226	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HKLHMGCA_01227	3.44e-95	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKLHMGCA_01228	8.77e-317	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HKLHMGCA_01229	4.96e-289	yttB	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_01230	9e-184	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKLHMGCA_01231	1.88e-291	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKLHMGCA_01233	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_01234	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKLHMGCA_01235	5.02e-277	glgC	2.7.7.27	-	H	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKLHMGCA_01236	3.49e-269	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HKLHMGCA_01237	0.0	glgA	2.4.1.21	GT5	F	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKLHMGCA_01238	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKLHMGCA_01239	0.0	malZ	3.2.1.20, 3.2.1.41	CBM48,GH13,GH31	G	ko:K01187,ko:K01200	ko00052,ko00500,ko01100,ko01110,map00052,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HKLHMGCA_01241	2.4e-183	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKLHMGCA_01242	1.1e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKLHMGCA_01243	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
HKLHMGCA_01244	3.21e-104	-	-	-	S	-	-	-	Pyridoxamine 5'-phosphate oxidase
HKLHMGCA_01245	4.37e-43	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein domain
HKLHMGCA_01246	2.54e-50	-	-	-	-	-	-	-	-
HKLHMGCA_01248	2.22e-169	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKLHMGCA_01249	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKLHMGCA_01250	3.55e-313	yycH	-	-	S	-	-	-	YycH protein
HKLHMGCA_01251	3.54e-195	yycI	-	-	S	-	-	-	YycH protein
HKLHMGCA_01252	1.71e-200	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HKLHMGCA_01253	1.5e-253	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HKLHMGCA_01254	6.08e-107	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKLHMGCA_01255	2.84e-123	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_01256	0.0	-	-	-	C	-	-	-	Belongs to the aldehyde dehydrogenase family
HKLHMGCA_01257	8.48e-215	-	-	-	L	-	-	-	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HKLHMGCA_01258	5.97e-157	ung2	-	-	L	-	-	-	Uracil-DNA glycosylase
HKLHMGCA_01259	1.34e-153	pnb	-	-	C	-	-	-	nitroreductase
HKLHMGCA_01260	4.95e-86	-	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	6-pyruvoyl tetrahydropterin synthase
HKLHMGCA_01261	1.57e-150	-	-	-	S	-	-	-	Elongation factor G-binding protein, N-terminal
HKLHMGCA_01262	0.0	-	-	-	C	-	-	-	FMN_bind
HKLHMGCA_01263	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKLHMGCA_01264	1.46e-204	-	-	-	K	-	-	-	LysR family
HKLHMGCA_01265	2.49e-95	-	-	-	C	-	-	-	FMN binding
HKLHMGCA_01266	4.48e-98	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKLHMGCA_01267	1.66e-210	-	-	-	S	-	-	-	KR domain
HKLHMGCA_01268	5.74e-204	adc	4.1.1.4	-	Q	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	ko00000,ko00001,ko00002,ko01000	Acetoacetate decarboxylase (ADC)
HKLHMGCA_01269	5.07e-157	ydgI	-	-	C	-	-	-	Nitroreductase family
HKLHMGCA_01270	0.0	-	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HKLHMGCA_01271	1.56e-154	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HKLHMGCA_01272	1.27e-247	pva1	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKLHMGCA_01273	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKLHMGCA_01274	6.86e-175	ptp1	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKLHMGCA_01275	0.0	hpaH	1.14.14.8, 1.14.14.9	-	Q	ko:K00483,ko:K16901	ko00350,ko00380,ko01120,ko01220,map00350,map00380,map01120,map01220	ko00000,ko00001,ko01000	4-hydroxyphenylacetate
HKLHMGCA_01276	1.36e-105	-	-	-	S	-	-	-	ASCH
HKLHMGCA_01277	4.35e-165	-	-	-	F	-	-	-	glutamine amidotransferase
HKLHMGCA_01278	1.67e-220	-	-	-	K	-	-	-	WYL domain
HKLHMGCA_01279	6.65e-152	azoR	-	-	C	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKLHMGCA_01280	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HKLHMGCA_01281	7.44e-51	-	-	-	S	-	-	-	Protein of unknown function
HKLHMGCA_01282	2.84e-81	-	-	-	S	-	-	-	Protein of unknown function
HKLHMGCA_01283	4.28e-195	-	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_01284	7.65e-121	yfbM	-	-	K	-	-	-	FR47-like protein
HKLHMGCA_01285	1.4e-162	-	-	-	S	-	-	-	DJ-1/PfpI family
HKLHMGCA_01286	3.14e-230	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKLHMGCA_01287	1.02e-63	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_01288	5.98e-302	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HKLHMGCA_01289	5.21e-214	pepI	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKLHMGCA_01290	7.76e-181	XK27_08125	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HKLHMGCA_01291	2.38e-99	-	-	-	-	-	-	-	-
HKLHMGCA_01292	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKLHMGCA_01293	2.4e-180	-	-	-	-	-	-	-	-
HKLHMGCA_01294	4.07e-05	-	-	-	-	-	-	-	-
HKLHMGCA_01295	5.66e-184	ant1	2.7.7.47	-	H	ko:K00984	-	ko00000,ko01000,ko01504	Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HKLHMGCA_01296	1.67e-54	-	-	-	-	-	-	-	-
HKLHMGCA_01297	4.29e-166	-	-	-	P	ko:K02006	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_01298	9.79e-192	-	-	-	P	ko:K02008	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HKLHMGCA_01299	1.84e-235	cbiM	-	-	P	ko:K02007	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	PDGLE domain
HKLHMGCA_01300	1.39e-156	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
HKLHMGCA_01301	7.9e-306	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HKLHMGCA_01302	2.65e-162	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKLHMGCA_01303	2.03e-179	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKLHMGCA_01304	6.32e-99	larC2	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Protein of unknown function DUF111
HKLHMGCA_01305	1.19e-170	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMGCA_01306	5.24e-193	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HKLHMGCA_01307	3.52e-227	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HKLHMGCA_01308	9.25e-176	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKLHMGCA_01309	1.18e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HKLHMGCA_01310	4.96e-139	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKLHMGCA_01311	2.4e-260	thiP	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKLHMGCA_01312	3.4e-174	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HKLHMGCA_01313	8.61e-155	-	-	-	L	-	-	-	HIRAN domain
HKLHMGCA_01314	9.94e-202	-	-	-	L	-	-	-	HIRAN domain
HKLHMGCA_01315	5.04e-109	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HKLHMGCA_01316	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HKLHMGCA_01317	1.27e-159	-	-	-	-	-	-	-	-
HKLHMGCA_01318	4.17e-191	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HKLHMGCA_01319	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HKLHMGCA_01320	1.23e-199	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKLHMGCA_01321	5.67e-64	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HKLHMGCA_01322	9.93e-127	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
HKLHMGCA_01323	0.0	pacL1	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKLHMGCA_01324	5.46e-183	-	-	-	F	-	-	-	Phosphorylase superfamily
HKLHMGCA_01325	2.92e-38	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HKLHMGCA_01326	1.72e-142	azo1	1.5.1.36, 1.7.1.6	-	S	ko:K03206,ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	NADPH-dependent FMN reductase
HKLHMGCA_01327	2.11e-97	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_01328	3.99e-96	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKLHMGCA_01329	5.51e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF3021)
HKLHMGCA_01330	5.38e-290	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HKLHMGCA_01331	3.98e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_01332	2.79e-274	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HKLHMGCA_01334	3.08e-148	morA	-	-	S	-	-	-	reductase
HKLHMGCA_01335	8.21e-213	-	1.1.1.65	-	C	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	ko00000,ko00001,ko01000	Aldo keto reductase
HKLHMGCA_01336	1.92e-106	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase like
HKLHMGCA_01337	0.0	l1n	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	Myosin-crossreactive antigen
HKLHMGCA_01338	4.29e-102	-	-	-	-	-	-	-	-
HKLHMGCA_01339	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_01340	3.75e-267	-	-	-	C	-	-	-	Oxidoreductase
HKLHMGCA_01341	3.28e-193	cbiQ	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKLHMGCA_01342	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_01343	2.57e-128	-	-	-	S	ko:K16924	-	ko00000,ko00002,ko02000	UPF0397 protein
HKLHMGCA_01345	4.37e-167	-	-	-	K	ko:K03492	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKLHMGCA_01346	4.14e-72	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
HKLHMGCA_01347	6.08e-180	-	-	-	-	-	-	-	-
HKLHMGCA_01348	1.57e-191	-	-	-	-	-	-	-	-
HKLHMGCA_01349	3.37e-115	-	-	-	-	-	-	-	-
HKLHMGCA_01350	1.01e-184	dhrS4	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Oxidoreductase, short chain dehydrogenase reductase family protein
HKLHMGCA_01351	2.46e-217	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_01352	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
HKLHMGCA_01353	8.03e-151	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HKLHMGCA_01354	0.0	etfA	1.3.1.108	-	C	ko:K03522,ko:K22432	-	ko00000,ko01000,ko04147	Electron transfer flavoprotein FAD-binding domain
HKLHMGCA_01355	2.04e-99	-	-	-	T	-	-	-	ECF transporter, substrate-specific component
HKLHMGCA_01357	1.85e-121	XK27_02085	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_01358	9.56e-243	dhaK2	2.7.1.28, 2.7.1.29, 4.6.1.15	-	G	ko:K00863	ko00051,ko00561,ko00680,ko01100,ko01120,ko01200,ko04622,map00051,map00561,map00680,map01100,map01120,map01200,map04622	ko00000,ko00001,ko00002,ko01000	Dak1 domain
HKLHMGCA_01359	1.58e-238	dhaK	2.7.1.121	-	G	ko:K05878	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak1 domain
HKLHMGCA_01360	2.75e-131	dhaL	2.7.1.121	-	S	ko:K05879	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Dak2
HKLHMGCA_01361	6.76e-75	dhaM	2.7.1.121	-	S	ko:K05881	ko00561,map00561	ko00000,ko00001,ko01000,ko02000	PTS system fructose IIA component
HKLHMGCA_01362	4e-172	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMGCA_01363	2.65e-245	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKLHMGCA_01364	1.83e-231	yvdE	-	-	K	-	-	-	helix_turn _helix lactose operon repressor
HKLHMGCA_01365	0.0	malA1	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain
HKLHMGCA_01366	9.45e-299	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HKLHMGCA_01367	3.74e-302	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_01368	2.83e-206	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_01369	2.91e-190	malA	-	-	S	-	-	-	maltodextrose utilization protein MalA
HKLHMGCA_01370	0.0	malS	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	Glycogen debranching enzyme, glucanotransferase domain
HKLHMGCA_01371	2.44e-267	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKLHMGCA_01372	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HKLHMGCA_01373	0.0	-	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Glycosyl hydrolase family 85
HKLHMGCA_01374	9.17e-52	ygbF	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HKLHMGCA_01375	1.27e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HKLHMGCA_01376	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKLHMGCA_01377	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_01378	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HKLHMGCA_01379	2.4e-230	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HKLHMGCA_01380	1.5e-73	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKLHMGCA_01381	4.34e-281	-	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKLHMGCA_01382	1.92e-209	-	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	nadph quinone reductase
HKLHMGCA_01383	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKLHMGCA_01384	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKLHMGCA_01385	2.22e-207	mleR	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_01386	0.0	-	-	-	M	-	-	-	domain protein
HKLHMGCA_01388	1.03e-201	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKLHMGCA_01389	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_01390	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_01391	7.83e-38	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_01392	1.31e-102	yiaC	-	-	K	ko:K03826	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HKLHMGCA_01393	1.19e-277	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMGCA_01394	1.24e-259	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKLHMGCA_01395	1.11e-146	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HKLHMGCA_01396	2.49e-229	yghZ	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKLHMGCA_01397	6.33e-46	-	-	-	-	-	-	-	-
HKLHMGCA_01398	1.35e-78	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HKLHMGCA_01399	4.56e-210	fbpA	-	-	K	-	-	-	Domain of unknown function (DUF814)
HKLHMGCA_01400	1.29e-278	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHMGCA_01401	3.81e-18	-	-	-	-	-	-	-	-
HKLHMGCA_01402	3.18e-77	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKLHMGCA_01403	5.66e-74	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKLHMGCA_01404	0.0	-	-	-	S	ko:K18231,ko:K19349	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ATPases associated with a variety of cellular activities
HKLHMGCA_01405	1.75e-149	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	cobalt transport
HKLHMGCA_01406	0.0	-	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKLHMGCA_01407	1.43e-131	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC transporter permease
HKLHMGCA_01408	2.28e-114	gpo	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HKLHMGCA_01409	1.77e-200	dkgB	-	-	S	-	-	-	reductase
HKLHMGCA_01410	1.28e-102	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKLHMGCA_01411	1.2e-91	-	-	-	-	-	-	-	-
HKLHMGCA_01412	1.06e-168	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKLHMGCA_01413	9.01e-221	-	-	-	P	-	-	-	Major Facilitator Superfamily
HKLHMGCA_01414	1.37e-283	-	-	-	C	-	-	-	FAD dependent oxidoreductase
HKLHMGCA_01415	4.94e-126	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_01416	0.0	pepD1	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKLHMGCA_01417	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKLHMGCA_01418	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	Mga helix-turn-helix domain
HKLHMGCA_01419	5.33e-103	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01420	1.06e-281	mtlD	1.1.1.17	-	C	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	mannitol-1-phosphate 5-dehydrogenase activity
HKLHMGCA_01421	2.84e-110	-	-	-	-	-	-	-	-
HKLHMGCA_01422	4.81e-76	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKLHMGCA_01423	5.92e-67	-	-	-	-	-	-	-	-
HKLHMGCA_01424	1.22e-125	-	-	-	-	-	-	-	-
HKLHMGCA_01425	2.98e-90	-	-	-	-	-	-	-	-
HKLHMGCA_01426	1.2e-106	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HKLHMGCA_01427	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HKLHMGCA_01428	2.21e-127	-	-	-	S	ko:K19784	-	ko00000	NADPH-dependent FMN reductase
HKLHMGCA_01429	1.89e-159	-	-	-	K	-	-	-	helix_turn_helix gluconate operon transcriptional repressor
HKLHMGCA_01430	1.93e-289	pts3C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01431	6.14e-53	-	-	-	-	-	-	-	-
HKLHMGCA_01432	1.08e-268	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKLHMGCA_01433	5.16e-271	dho	3.5.2.3	-	S	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Amidohydrolase family
HKLHMGCA_01434	2.92e-258	selA	2.9.1.1	-	H	ko:K01042	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko01000	L-seryl-tRNA selenium transferase
HKLHMGCA_01435	1.22e-166	-	4.1.2.14	-	S	ko:K17463	ko00030,ko01100,ko01120,map00030,map01100,map01120	ko00000,ko00001,ko00002,ko01000	KDGP aldolase
HKLHMGCA_01436	7.87e-243	-	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	pfkB family carbohydrate kinase
HKLHMGCA_01437	2.13e-124	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Bacterial transferase hexapeptide (six repeats)
HKLHMGCA_01438	1.17e-267	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HKLHMGCA_01439	7.54e-211	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HKLHMGCA_01440	6.72e-203	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HKLHMGCA_01441	1.27e-181	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKLHMGCA_01442	7.55e-58	-	-	-	S	-	-	-	Protein of unknown function (DUF2089)
HKLHMGCA_01443	2.21e-56	-	-	-	-	-	-	-	-
HKLHMGCA_01444	1.68e-166	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKLHMGCA_01445	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
HKLHMGCA_01446	0.0	pts4ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HKLHMGCA_01447	0.0	pts5ABC	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKLHMGCA_01448	6.12e-184	-	-	-	-	-	-	-	-
HKLHMGCA_01449	1.21e-94	tagD	2.7.7.15, 2.7.7.39	-	IM	ko:K00968,ko:K00980	ko00440,ko00564,ko01100,ko05231,map00440,map00564,map01100,map05231	ko00000,ko00001,ko00002,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKLHMGCA_01450	8.12e-306	tagB	2.7.8.12, 2.7.8.45	-	M	ko:K09809,ko:K21591	-	ko00000,ko01000	glycerophosphotransferase
HKLHMGCA_01451	0.0	tagF2	2.7.8.12	-	H	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKLHMGCA_01452	3.37e-129	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKLHMGCA_01453	2.73e-92	-	-	-	-	-	-	-	-
HKLHMGCA_01454	2.26e-269	-	-	-	S	ko:K09963	-	ko00000	Bacterial protein of unknown function (DUF871)
HKLHMGCA_01455	5.64e-201	-	-	-	G	-	-	-	BadF/BadG/BcrA/BcrD ATPase family
HKLHMGCA_01456	5.07e-211	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKLHMGCA_01457	1.87e-316	pts29C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01458	5.44e-174	-	-	-	K	-	-	-	UTRA domain
HKLHMGCA_01459	2.63e-200	estA	-	-	S	-	-	-	Putative esterase
HKLHMGCA_01460	4.93e-82	-	-	-	-	-	-	-	-
HKLHMGCA_01461	1.12e-262	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKLHMGCA_01462	1.73e-215	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKLHMGCA_01463	5.56e-212	-	-	-	G	-	-	-	Xylose isomerase-like TIM barrel
HKLHMGCA_01464	1.64e-202	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl-(Acyl carrier protein) reductase
HKLHMGCA_01465	8.13e-206	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLHMGCA_01466	1.71e-207	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLHMGCA_01467	1.4e-282	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKLHMGCA_01468	4.62e-224	-	-	-	K	-	-	-	Transcriptional regulator, LysR family
HKLHMGCA_01469	1.12e-212	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLHMGCA_01470	3.65e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKLHMGCA_01471	1.23e-228	apbE3	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLHMGCA_01472	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKLHMGCA_01473	2.02e-85	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HKLHMGCA_01474	8.93e-249	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HKLHMGCA_01475	3.69e-232	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKLHMGCA_01476	4.27e-253	galM3	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKLHMGCA_01477	0.0	lacP	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HKLHMGCA_01478	0.0	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKLHMGCA_01479	1.64e-238	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HKLHMGCA_01480	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HKLHMGCA_01481	1.65e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKLHMGCA_01482	1.26e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKLHMGCA_01483	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HKLHMGCA_01484	1.19e-234	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HKLHMGCA_01485	3.4e-100	-	-	-	K	ko:K07726	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HKLHMGCA_01486	6.22e-140	fic	-	-	D	ko:K04095	-	ko00000,ko03036	Fic/DOC family
HKLHMGCA_01487	5.27e-235	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKLHMGCA_01488	5.06e-298	-	-	-	P	ko:K06610	-	ko00000,ko02000	Major Facilitator Superfamily
HKLHMGCA_01489	0.0	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKLHMGCA_01490	5.02e-294	-	-	-	P	ko:K06610	-	ko00000,ko02000	Sugar (and other) transporter
HKLHMGCA_01491	0.0	-	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKLHMGCA_01492	1.13e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding protein-like domain
HKLHMGCA_01493	8.86e-298	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01494	2.81e-90	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKLHMGCA_01495	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HKLHMGCA_01496	5.67e-212	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	-beta-galactosidase
HKLHMGCA_01497	1.11e-84	-	-	-	-	-	-	-	-
HKLHMGCA_01498	2e-98	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	general stress protein
HKLHMGCA_01499	5.16e-141	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKLHMGCA_01500	8.38e-152	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HKLHMGCA_01501	4.69e-151	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HKLHMGCA_01502	7.18e-189	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKLHMGCA_01503	1.96e-116	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HKLHMGCA_01504	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HKLHMGCA_01505	1.66e-150	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKLHMGCA_01506	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKLHMGCA_01507	6.4e-280	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHMGCA_01508	1.56e-236	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HKLHMGCA_01510	6.46e-113	-	-	-	S	-	-	-	Prokaryotic N-terminal methylation motif
HKLHMGCA_01511	3.03e-27	-	-	-	-	ko:K02671	-	ko00000,ko02035,ko02044	-
HKLHMGCA_01512	4.29e-108	-	-	-	NU	ko:K02246	-	ko00000,ko00002,ko02044	general secretion pathway protein
HKLHMGCA_01513	1.97e-72	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HKLHMGCA_01514	6.2e-242	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HKLHMGCA_01515	2.57e-224	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HKLHMGCA_01516	2.06e-205	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKLHMGCA_01517	2.21e-168	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HKLHMGCA_01518	2.44e-65	-	-	-	S	ko:K09004	-	ko00000	DsrE/DsrF-like family
HKLHMGCA_01519	7.88e-211	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HKLHMGCA_01520	5.44e-232	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HKLHMGCA_01521	8.96e-275	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKLHMGCA_01522	9.11e-106	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_01523	1.6e-96	-	-	-	-	-	-	-	-
HKLHMGCA_01524	1.88e-75	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKLHMGCA_01525	1.9e-201	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HKLHMGCA_01526	6.72e-289	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKLHMGCA_01527	2.29e-112	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKLHMGCA_01528	7.94e-114	ykuL	-	-	S	-	-	-	(CBS) domain
HKLHMGCA_01529	4.03e-125	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HKLHMGCA_01530	8.49e-144	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKLHMGCA_01531	5.06e-194	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HKLHMGCA_01532	1.45e-161	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HKLHMGCA_01533	3e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HKLHMGCA_01534	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKLHMGCA_01535	1.06e-49	-	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKLHMGCA_01536	1.31e-63	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HKLHMGCA_01537	5.39e-96	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKLHMGCA_01538	5e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HKLHMGCA_01539	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKLHMGCA_01540	2.79e-316	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKLHMGCA_01541	8.32e-227	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HKLHMGCA_01542	2.48e-276	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKLHMGCA_01543	1.26e-61	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKLHMGCA_01544	9.91e-289	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKLHMGCA_01545	5.87e-256	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKLHMGCA_01546	2.62e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKLHMGCA_01547	2.83e-138	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKLHMGCA_01548	2.83e-114	-	-	-	-	-	-	-	-
HKLHMGCA_01549	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HKLHMGCA_01550	1.3e-91	-	-	-	-	-	-	-	-
HKLHMGCA_01551	4.08e-187	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKLHMGCA_01552	3.84e-260	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKLHMGCA_01555	6.36e-32	-	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HKLHMGCA_01558	2.81e-154	-	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HKLHMGCA_01564	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	C-terminal repeat of topoisomerase
HKLHMGCA_01565	1.59e-124	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
HKLHMGCA_01566	1.74e-79	Z012_00440	-	-	L	ko:K07483	-	ko00000	transposase activity
HKLHMGCA_01567	2.01e-17	XK27_07075	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01577	3.41e-52	-	-	-	S	-	-	-	Protein of unknown function (DUF3102)
HKLHMGCA_01579	2.29e-118	-	-	-	M	-	-	-	CHAP domain
HKLHMGCA_01581	1.46e-116	-	-	-	S	-	-	-	COG0433 Predicted ATPase
HKLHMGCA_01585	1.11e-115	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
HKLHMGCA_01586	1.55e-78	-	-	-	D	-	-	-	AAA domain
HKLHMGCA_01588	1.57e-296	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKLHMGCA_01589	3.41e-47	-	-	-	-	-	-	-	-
HKLHMGCA_01590	5.11e-44	-	-	-	-	-	-	-	-
HKLHMGCA_01591	7.03e-64	-	-	-	KLT	-	-	-	serine threonine protein kinase
HKLHMGCA_01592	1.47e-126	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_01594	1.57e-176	-	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HKLHMGCA_01595	9.73e-06	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKLHMGCA_01598	1.18e-123	-	-	-	L	-	-	-	Resolvase, N terminal domain
HKLHMGCA_01599	3.74e-125	-	-	-	V	-	-	-	VanZ like family
HKLHMGCA_01600	1.26e-247	-	-	-	V	-	-	-	Beta-lactamase
HKLHMGCA_01601	0.0	pflB	2.3.1.54	-	C	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	ko00000,ko00001,ko01000	Pyruvate formate lyase-like
HKLHMGCA_01602	1.12e-206	pflA	1.97.1.4	-	C	ko:K04069	-	ko00000,ko01000	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKLHMGCA_01603	8.93e-71	-	-	-	S	-	-	-	Pfam:DUF59
HKLHMGCA_01604	6.07e-223	ydhF	-	-	S	-	-	-	Aldo keto reductase
HKLHMGCA_01605	2.42e-127	-	-	-	FG	-	-	-	HIT domain
HKLHMGCA_01606	9.9e-49	-	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HKLHMGCA_01607	4.29e-101	-	-	-	-	-	-	-	-
HKLHMGCA_01608	8.79e-156	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKLHMGCA_01609	0.0	-	-	-	U	ko:K03451	-	ko00000	Belongs to the BCCT transporter (TC 2.A.15) family
HKLHMGCA_01610	0.0	cadA	-	-	P	-	-	-	P-type ATPase
HKLHMGCA_01612	2.32e-160	-	-	-	S	-	-	-	YjbR
HKLHMGCA_01613	3.05e-281	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HKLHMGCA_01614	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKLHMGCA_01615	7.12e-256	glmS2	-	-	M	-	-	-	SIS domain
HKLHMGCA_01616	3.58e-36	-	-	-	S	-	-	-	Belongs to the LOG family
HKLHMGCA_01617	0.0	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HKLHMGCA_01618	1.81e-316	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HKLHMGCA_01619	4.58e-216	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_01620	4.75e-112	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HKLHMGCA_01621	6.47e-208	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_01622	2.14e-86	-	-	-	K	ko:K22296	-	ko00000,ko03000	Winged helix DNA-binding domain
HKLHMGCA_01623	9.97e-94	spxA	-	-	P	ko:K16509	-	ko00000	ArsC family
HKLHMGCA_01624	3.46e-87	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HKLHMGCA_01625	1.7e-70	-	-	-	-	-	-	-	-
HKLHMGCA_01626	4.98e-275	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific adenine glycosylase
HKLHMGCA_01627	1.22e-81	-	-	-	-	-	-	-	-
HKLHMGCA_01628	1.36e-112	-	-	-	-	-	-	-	-
HKLHMGCA_01629	4.58e-103	hsp3	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HKLHMGCA_01630	3.78e-73	-	-	-	-	-	-	-	-
HKLHMGCA_01631	4.79e-21	-	-	-	-	-	-	-	-
HKLHMGCA_01632	3.57e-150	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_01633	2.52e-107	-	-	-	S	ko:K02348	-	ko00000	GNAT family
HKLHMGCA_01634	9.43e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_01635	2.66e-155	-	-	-	S	-	-	-	membrane
HKLHMGCA_01636	1.47e-144	-	-	-	S	-	-	-	VIT family
HKLHMGCA_01637	4.38e-243	pva2	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HKLHMGCA_01638	0.0	copB	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKLHMGCA_01639	8.01e-97	copR	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HKLHMGCA_01640	4.26e-54	-	-	-	-	-	-	-	-
HKLHMGCA_01641	3.43e-96	-	-	-	S	-	-	-	COG NOG18757 non supervised orthologous group
HKLHMGCA_01642	8.8e-315	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HKLHMGCA_01643	0.0	-	-	-	S	-	-	-	membrane
HKLHMGCA_01644	4.29e-26	-	-	-	S	-	-	-	NUDIX domain
HKLHMGCA_01645	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKLHMGCA_01646	1.15e-235	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HKLHMGCA_01647	1.17e-100	-	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	Nucleoside 2-deoxyribosyltransferase
HKLHMGCA_01648	4.43e-129	-	-	-	-	-	-	-	-
HKLHMGCA_01649	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HKLHMGCA_01650	9.9e-144	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKLHMGCA_01651	6.59e-227	-	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_01652	2.41e-233	-	-	-	M	-	-	-	Peptidase family S41
HKLHMGCA_01653	3.91e-58	-	-	-	-	-	-	-	-
HKLHMGCA_01654	3.54e-153	-	-	-	-	-	-	-	-
HKLHMGCA_01655	1.03e-240	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHMGCA_01656	0.0	yhaN	-	-	L	-	-	-	AAA domain
HKLHMGCA_01657	4.47e-296	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	Ser Thr phosphatase family protein
HKLHMGCA_01658	9.94e-71	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HKLHMGCA_01659	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HKLHMGCA_01660	2.43e-18	-	-	-	-	-	-	-	-
HKLHMGCA_01661	2.07e-102	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKLHMGCA_01662	5.58e-271	arcT	-	-	E	-	-	-	Aminotransferase
HKLHMGCA_01663	8.08e-133	argO	-	-	S	ko:K06895	-	ko00000,ko02000	LysE type translocator
HKLHMGCA_01664	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	Alanine-glyoxylate amino-transferase
HKLHMGCA_01665	1.65e-46	dltC2	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKLHMGCA_01666	1.72e-148	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HKLHMGCA_01667	7.06e-271	-	-	-	EGP	ko:K08218	ko01501,map01501	ko00000,ko00001,ko00002,ko02000	Major facilitator Superfamily
HKLHMGCA_01668	8.06e-26	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01669	0.0	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01670	1.02e-285	-	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01671	4.9e-64	-	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKLHMGCA_01672	2.37e-68	lacF	2.7.1.196, 2.7.1.205, 2.7.1.207	-	G	ko:K02759,ko:K02786	ko00052,ko00500,ko01100,ko02060,map00052,map00500,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKLHMGCA_01673	1.34e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKLHMGCA_01674	0.0	celR	-	-	K	-	-	-	PRD domain
HKLHMGCA_01675	6.25e-138	-	-	-	-	-	-	-	-
HKLHMGCA_01676	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKLHMGCA_01677	4.64e-106	-	-	-	-	-	-	-	-
HKLHMGCA_01678	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HKLHMGCA_01679	8.2e-102	yybD	-	-	S	ko:K02348	-	ko00000	Acetyltransferase (GNAT) domain
HKLHMGCA_01682	1.79e-42	-	-	-	-	-	-	-	-
HKLHMGCA_01683	6.28e-316	dinF	-	-	V	-	-	-	MatE
HKLHMGCA_01684	2.55e-90	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_01685	9.06e-35	-	-	-	M	-	-	-	domain protein
HKLHMGCA_01687	3.25e-133	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HKLHMGCA_01688	8.88e-55	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HKLHMGCA_01689	1.23e-108	lytT	-	-	K	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator receiver
HKLHMGCA_01690	1.27e-314	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	LytS YhcK-type transmembrane receptor domain protein
HKLHMGCA_01693	1.53e-125	-	-	-	S	-	-	-	Protease prsW family
HKLHMGCA_01694	3.7e-123	-	-	-	L	-	-	-	Resolvase, N terminal domain
HKLHMGCA_01696	8.72e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKLHMGCA_01697	9.33e-249	-	-	-	U	ko:K07085	-	ko00000	Predicted Permease Membrane Region
HKLHMGCA_01698	5.32e-298	aspD	4.1.1.12	-	E	ko:K09758	ko00250,ko00270,ko01100,ko01230,map00250,map00270,map01100,map01230	ko00000,ko00001,ko01000	Aminotransferase class I and II
HKLHMGCA_01699	1.48e-81	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKLHMGCA_01700	8.72e-163	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKLHMGCA_01701	5.07e-290	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKLHMGCA_01702	9.81e-112	-	-	-	K	-	-	-	LysR family
HKLHMGCA_01703	3.37e-136	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
HKLHMGCA_01704	4.67e-236	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
HKLHMGCA_01705	7.52e-100	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
HKLHMGCA_01706	1.02e-142	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HKLHMGCA_01707	3.19e-107	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
HKLHMGCA_01709	8.43e-32	-	-	-	-	-	-	-	-
HKLHMGCA_01710	0.0	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKLHMGCA_01711	1.92e-71	-	-	-	-	-	-	-	-
HKLHMGCA_01712	1.14e-78	-	-	-	-	-	-	-	-
HKLHMGCA_01713	9.36e-111	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_01714	6.36e-241	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_01715	2.63e-44	-	-	-	-	-	-	-	-
HKLHMGCA_01716	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKLHMGCA_01717	0.0	-	-	-	L	-	-	-	MobA MobL family protein
HKLHMGCA_01718	4.32e-23	-	-	-	-	-	-	-	-
HKLHMGCA_01720	3.24e-27	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_01721	1.32e-19	-	-	-	K	-	-	-	Helix-turn-helix
HKLHMGCA_01722	7.71e-126	-	-	-	K	-	-	-	ORF6N domain
HKLHMGCA_01723	1.53e-11	-	-	-	-	-	-	-	-
HKLHMGCA_01729	7.4e-52	-	-	-	S	-	-	-	Siphovirus Gp157
HKLHMGCA_01730	1.64e-200	-	-	-	S	-	-	-	helicase activity
HKLHMGCA_01731	1.17e-10	-	-	-	S	-	-	-	HNH endonuclease
HKLHMGCA_01732	3.53e-93	-	-	-	L	-	-	-	AAA domain
HKLHMGCA_01733	4.96e-27	-	-	-	-	-	-	-	-
HKLHMGCA_01734	3.84e-96	-	-	-	S	-	-	-	Bifunctional DNA primase/polymerase, N-terminal
HKLHMGCA_01735	3.08e-163	-	-	-	S	ko:K06919	-	ko00000	Virulence-associated protein E
HKLHMGCA_01736	5.43e-51	-	-	-	S	-	-	-	hydrolase activity, acting on ester bonds
HKLHMGCA_01737	6.06e-05	-	-	-	-	-	-	-	-
HKLHMGCA_01738	2.52e-139	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HKLHMGCA_01739	5.06e-29	-	-	-	-	-	-	-	-
HKLHMGCA_01741	3.33e-43	-	-	-	-	-	-	-	-
HKLHMGCA_01747	5.46e-13	-	-	-	-	-	-	-	-
HKLHMGCA_01748	2.45e-213	-	-	-	S	-	-	-	Terminase
HKLHMGCA_01749	7.12e-128	-	-	-	S	-	-	-	Phage portal protein
HKLHMGCA_01750	2.3e-70	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Clp protease
HKLHMGCA_01751	1.83e-140	-	-	-	S	-	-	-	Phage capsid family
HKLHMGCA_01752	2.16e-27	-	-	-	-	-	-	-	-
HKLHMGCA_01753	4.2e-34	-	-	-	-	-	-	-	-
HKLHMGCA_01754	3.9e-49	-	-	-	-	-	-	-	-
HKLHMGCA_01755	1.1e-41	-	-	-	-	-	-	-	-
HKLHMGCA_01756	4.99e-67	-	-	-	S	-	-	-	Phage tail tube protein
HKLHMGCA_01758	2.5e-189	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
HKLHMGCA_01759	3.89e-67	-	-	-	S	-	-	-	phage tail
HKLHMGCA_01760	1.61e-77	-	-	-	M	-	-	-	Prophage endopeptidase tail
HKLHMGCA_01761	4.76e-05	-	-	-	C	-	-	-	Glycerophosphoryl diester phosphodiesterase family
HKLHMGCA_01763	5.1e-106	mutR	-	-	K	ko:K20373,ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	sequence-specific DNA binding
HKLHMGCA_01764	1.81e-273	-	-	-	EGP	ko:K02030	-	ko00000,ko00002,ko02000	Drug resistance transporter Bcr CflA subfamily
HKLHMGCA_01765	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKLHMGCA_01766	4.64e-92	-	-	-	F	-	-	-	DNA mismatch repair protein MutT
HKLHMGCA_01767	1.12e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HKLHMGCA_01768	2.14e-171	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HKLHMGCA_01769	5.43e-228	-	-	-	-	-	-	-	-
HKLHMGCA_01770	1.37e-290	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HKLHMGCA_01771	1.36e-214	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKLHMGCA_01772	1.2e-243	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLHMGCA_01773	1.6e-77	chpA	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKLHMGCA_01774	5.9e-46	-	-	-	-	-	-	-	-
HKLHMGCA_01775	1.69e-97	-	-	-	S	-	-	-	Domain of unknown function (DUF3284)
HKLHMGCA_01776	9.68e-34	-	-	-	-	-	-	-	-
HKLHMGCA_01777	0.0	chbC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01778	2.69e-166	-	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HKLHMGCA_01779	2.35e-243	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHMGCA_01780	5.87e-181	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HKLHMGCA_01781	0.0	-	-	-	L	-	-	-	DNA helicase
HKLHMGCA_01782	4.23e-64	axe	-	-	K	ko:K21498	-	ko00000,ko02048	Helix-turn-helix XRE-family like proteins
HKLHMGCA_01783	1.59e-145	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01784	1.86e-143	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01785	8.02e-152	plnU	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01786	1.83e-140	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01787	1.17e-306	mesE	-	-	M	ko:K12293,ko:K20345	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko02000	Transport protein ComB
HKLHMGCA_01788	3.13e-278	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKLHMGCA_01789	1.65e-199	comA	-	-	V	ko:K06147,ko:K06148,ko:K12292,ko:K20344	ko02010,ko02020,ko02024,map02010,map02020,map02024	ko00000,ko00001,ko01000,ko02000	ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HKLHMGCA_01790	2.59e-19	-	-	-	-	-	-	-	-
HKLHMGCA_01791	1.93e-31	plnF	-	-	-	-	-	-	-
HKLHMGCA_01792	8.15e-167	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01793	1.73e-148	plnD	-	-	K	ko:K07707	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HKLHMGCA_01794	5.31e-285	-	-	-	M	-	-	-	Glycosyl transferases group 1
HKLHMGCA_01795	1.38e-30	-	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HKLHMGCA_01796	4.05e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKLHMGCA_01797	9.59e-09	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKLHMGCA_01799	1.09e-55	-	-	-	S	-	-	-	zinc-ribbon domain
HKLHMGCA_01800	3.77e-24	-	-	-	-	-	-	-	-
HKLHMGCA_01801	3.4e-201	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HKLHMGCA_01802	1.02e-102	uspA3	-	-	T	-	-	-	universal stress protein
HKLHMGCA_01803	5.87e-166	-	-	-	K	ko:K03710	-	ko00000,ko03000	helix_turn_helix gluconate operon transcriptional repressor
HKLHMGCA_01804	1.49e-112	-	2.7.1.191	-	K	ko:K02745,ko:K02794,ko:K10984	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKLHMGCA_01805	5.2e-185	-	-	-	G	ko:K02746,ko:K10985	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sorbose-specific iic component
HKLHMGCA_01806	3.82e-188	agaD	-	-	G	ko:K02747,ko:K02796,ko:K10986	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system mannose/fructose/sorbose family IID component
HKLHMGCA_01807	1.63e-95	-	-	-	G	ko:K02744	ko00052,ko02060,map00052,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKLHMGCA_01808	0.0	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Bacterial SH3 domain
HKLHMGCA_01809	1e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HKLHMGCA_01810	4.15e-78	-	-	-	-	-	-	-	-
HKLHMGCA_01811	4.05e-98	-	-	-	-	-	-	-	-
HKLHMGCA_01812	6.94e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2798)
HKLHMGCA_01813	1.57e-71	-	-	-	-	-	-	-	-
HKLHMGCA_01814	3.89e-62	-	-	-	-	-	-	-	-
HKLHMGCA_01815	6.69e-263	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HKLHMGCA_01816	9.89e-74	ytpP	-	-	CO	-	-	-	Thioredoxin
HKLHMGCA_01817	1.97e-185	-	-	-	S	ko:K06889	-	ko00000	Dienelactone hydrolase family
HKLHMGCA_01818	5.82e-89	-	-	-	-	-	-	-	-
HKLHMGCA_01819	0.0	spxB	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKLHMGCA_01820	4.83e-64	-	-	-	-	-	-	-	-
HKLHMGCA_01821	3.68e-77	-	-	-	-	-	-	-	-
HKLHMGCA_01823	2.64e-210	-	-	-	-	-	-	-	-
HKLHMGCA_01824	1.4e-95	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_01825	0.0	pepF2	-	-	E	-	-	-	Oligopeptidase F
HKLHMGCA_01826	4.62e-223	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKLHMGCA_01827	7.2e-61	-	-	-	S	-	-	-	Enterocin A Immunity
HKLHMGCA_01828	8.34e-86	lexA	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator, GntR family
HKLHMGCA_01829	5e-162	skfE	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_01830	2.66e-172	-	-	-	-	-	-	-	-
HKLHMGCA_01831	9.38e-139	pncA	-	-	Q	-	-	-	Isochorismatase family
HKLHMGCA_01832	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKLHMGCA_01833	3.07e-65	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKLHMGCA_01834	0.0	nhaP2	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKLHMGCA_01835	8.97e-253	yhhX	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HKLHMGCA_01836	9.51e-49	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKLHMGCA_01837	1.55e-49	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKLHMGCA_01838	4.07e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HKLHMGCA_01839	9.95e-92	-	-	-	S	-	-	-	Oxidoreductase family, NAD-binding Rossmann fold
HKLHMGCA_01840	4.16e-150	-	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKLHMGCA_01841	1.48e-201	ccpB	-	-	K	-	-	-	lacI family
HKLHMGCA_01842	2.2e-157	-	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKLHMGCA_01843	3.45e-209	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKLHMGCA_01844	1.23e-228	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HKLHMGCA_01845	2.57e-128	-	-	-	C	-	-	-	Nitroreductase family
HKLHMGCA_01846	6.04e-217	-	-	-	S	-	-	-	Polyphosphate kinase 2 (PPK2)
HKLHMGCA_01847	2.35e-247	-	-	-	S	-	-	-	domain, Protein
HKLHMGCA_01848	2.14e-183	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_01849	4.01e-236	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HKLHMGCA_01850	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKLHMGCA_01851	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HKLHMGCA_01852	3e-98	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_01853	0.0	-	-	-	M	-	-	-	domain protein
HKLHMGCA_01854	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKLHMGCA_01855	1.26e-143	-	-	-	S	-	-	-	Protein of unknown function (DUF1211)
HKLHMGCA_01856	1.45e-46	-	-	-	-	-	-	-	-
HKLHMGCA_01857	9.88e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HKLHMGCA_01858	1.69e-255	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKLHMGCA_01859	4.54e-126	-	-	-	J	-	-	-	glyoxalase III activity
HKLHMGCA_01860	2.49e-190	-	-	-	GM	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_01861	4.73e-118	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HKLHMGCA_01862	6.7e-74	-	-	-	S	-	-	-	Domain of unknown function (DU1801)
HKLHMGCA_01863	7.28e-213	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HKLHMGCA_01864	1.24e-281	ysaA	-	-	V	-	-	-	RDD family
HKLHMGCA_01865	3.2e-208	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Histidinol phosphate phosphatase, HisJ
HKLHMGCA_01866	4.44e-273	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKLHMGCA_01867	1.69e-151	hisG	2.4.2.17	-	F	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKLHMGCA_01868	1.92e-299	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKLHMGCA_01869	2.46e-139	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HKLHMGCA_01870	2.23e-142	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKLHMGCA_01871	6.84e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKLHMGCA_01872	1.27e-172	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKLHMGCA_01873	6.12e-78	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HKLHMGCA_01874	1.07e-68	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HKLHMGCA_01875	4.48e-257	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKLHMGCA_01876	4.99e-125	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKLHMGCA_01877	1.01e-176	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HKLHMGCA_01878	9.51e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HKLHMGCA_01879	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKLHMGCA_01880	1.32e-178	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_01881	7.03e-195	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKLHMGCA_01882	1.13e-225	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_01883	1.53e-213	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HKLHMGCA_01884	6.08e-312	metY	2.5.1.49	-	E	ko:K01740	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko01000	Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HKLHMGCA_01885	1.01e-293	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HKLHMGCA_01886	3.45e-209	-	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKLHMGCA_01887	4.37e-241	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKLHMGCA_01888	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKLHMGCA_01889	9.2e-62	-	-	-	-	-	-	-	-
HKLHMGCA_01890	3.9e-105	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKLHMGCA_01891	9.24e-140	-	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HKLHMGCA_01892	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKLHMGCA_01893	2.58e-274	-	-	-	T	-	-	-	diguanylate cyclase
HKLHMGCA_01894	1.11e-45	-	-	-	-	-	-	-	-
HKLHMGCA_01895	2.29e-48	-	-	-	-	-	-	-	-
HKLHMGCA_01896	5.92e-107	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HKLHMGCA_01897	2.47e-222	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	NlpC/P60 family
HKLHMGCA_01898	1.65e-206	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_01900	2.68e-32	-	-	-	-	-	-	-	-
HKLHMGCA_01901	8.05e-178	-	-	-	F	-	-	-	NUDIX domain
HKLHMGCA_01902	6.83e-274	yceI	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major Facilitator
HKLHMGCA_01903	1.86e-64	-	-	-	-	-	-	-	-
HKLHMGCA_01904	6.24e-120	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HKLHMGCA_01906	1.48e-217	-	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_01907	6.12e-51	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HKLHMGCA_01908	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HKLHMGCA_01909	1.45e-173	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HKLHMGCA_01910	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HKLHMGCA_01911	1.83e-277	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	S-adenosylmethionine-dependent methyltransferase
HKLHMGCA_01912	2.51e-200	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKLHMGCA_01913	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HKLHMGCA_01914	2.1e-33	-	-	-	-	-	-	-	-
HKLHMGCA_01915	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_01916	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKLHMGCA_01917	0.0	-	3.6.3.44	-	P	ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter transmembrane region
HKLHMGCA_01918	4.63e-24	-	-	-	-	-	-	-	-
HKLHMGCA_01919	2.16e-26	-	-	-	-	-	-	-	-
HKLHMGCA_01920	9.35e-24	-	-	-	-	-	-	-	-
HKLHMGCA_01921	9.35e-24	-	-	-	-	-	-	-	-
HKLHMGCA_01922	1.07e-26	-	-	-	-	-	-	-	-
HKLHMGCA_01923	1.56e-22	-	-	-	-	-	-	-	-
HKLHMGCA_01924	3.26e-24	-	-	-	-	-	-	-	-
HKLHMGCA_01925	6.58e-24	-	-	-	-	-	-	-	-
HKLHMGCA_01928	6.19e-208	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_01929	1.2e-206	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HKLHMGCA_01930	1.66e-211	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HKLHMGCA_01931	2.45e-101	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HKLHMGCA_01932	0.0	ycaM	-	-	E	-	-	-	amino acid
HKLHMGCA_01933	2.38e-164	aroC1	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Type I 3-dehydroquinase
HKLHMGCA_01934	4.3e-44	-	-	-	-	-	-	-	-
HKLHMGCA_01935	0.0	-	-	-	M	-	-	-	Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HKLHMGCA_01936	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKLHMGCA_01937	1.17e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HKLHMGCA_01938	0.0	-	-	-	-	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	-
HKLHMGCA_01939	3.78e-132	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKLHMGCA_01940	4.12e-226	serA1	-	-	EH	-	-	-	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HKLHMGCA_01941	2.25e-73	-	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_01942	1.2e-107	-	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_01943	2.05e-233	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKLHMGCA_01944	5.06e-196	-	-	-	S	-	-	-	hydrolase
HKLHMGCA_01945	7.63e-107	-	-	-	-	-	-	-	-
HKLHMGCA_01946	1.75e-156	pgm7	-	-	G	-	-	-	Phosphoglycerate mutase family
HKLHMGCA_01947	1.4e-181	epsV	-	-	S	-	-	-	glycosyl transferase family 2
HKLHMGCA_01948	6.37e-169	gntR	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKLHMGCA_01949	1.86e-64	pts20B	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKLHMGCA_01950	6.7e-74	celC	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose Cellobiose specific IIA subunit
HKLHMGCA_01951	0.0	pbg5	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01952	0.0	pbg4	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_01953	9.53e-317	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HKLHMGCA_01954	9.59e-157	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01955	1.32e-170	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_01956	4.87e-156	vex2	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_01957	8.31e-292	vex3	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	MacB-like periplasmic core domain
HKLHMGCA_01958	0.0	-	-	-	S	-	-	-	Leucine-rich repeat (LRR) protein
HKLHMGCA_01959	5.62e-137	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKLHMGCA_01960	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HKLHMGCA_01961	1.17e-135	-	-	-	K	-	-	-	transcriptional regulator
HKLHMGCA_01962	1.41e-141	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HKLHMGCA_01963	1.49e-63	-	-	-	-	-	-	-	-
HKLHMGCA_01964	0.0	loxD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	FAD linked oxidases, C-terminal domain
HKLHMGCA_01965	7.18e-236	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKLHMGCA_01966	2.87e-56	-	-	-	-	-	-	-	-
HKLHMGCA_01967	3.35e-75	-	-	-	-	-	-	-	-
HKLHMGCA_01968	6.86e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_01969	1.96e-167	yidA	-	-	K	-	-	-	Helix-turn-helix domain, rpiR family
HKLHMGCA_01970	2.42e-65	-	-	-	-	-	-	-	-
HKLHMGCA_01971	1.9e-165	rrp2	-	-	K	-	-	-	Transcriptional regulatory protein, C terminal
HKLHMGCA_01972	0.0	hpk2	-	-	T	-	-	-	Histidine kinase
HKLHMGCA_01973	2.39e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_01974	0.0	ydiC	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_01975	1.55e-55	-	-	-	-	-	-	-	-
HKLHMGCA_01976	4.48e-52	-	-	-	-	-	-	-	-
HKLHMGCA_01977	1.15e-152	-	-	-	-	-	-	-	-
HKLHMGCA_01978	5.71e-301	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKLHMGCA_01979	8.62e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_01980	8.9e-96	ywnA	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_01981	1.8e-46	-	-	-	-	-	-	-	-
HKLHMGCA_01982	3.41e-107	-	-	-	L	-	-	-	Transposase DDE domain
HKLHMGCA_01983	2.52e-76	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKLHMGCA_01984	1.09e-280	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKLHMGCA_01985	0.0	-	-	-	P	-	-	-	Cation transporter/ATPase, N-terminus
HKLHMGCA_01986	7.27e-57	-	-	-	-	-	-	-	-
HKLHMGCA_01987	4.68e-192	-	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	CobQ CobB MinD ParA nucleotide binding domain protein
HKLHMGCA_01988	2.07e-46	-	-	-	-	-	-	-	-
HKLHMGCA_01989	5.2e-224	repA	-	-	S	-	-	-	Replication initiator protein A
HKLHMGCA_01990	9.37e-159	-	-	-	S	-	-	-	Fic/DOC family
HKLHMGCA_01991	3.34e-52	-	-	-	-	-	-	-	-
HKLHMGCA_01992	3.11e-34	-	-	-	-	-	-	-	-
HKLHMGCA_01993	0.0	traA	-	-	L	-	-	-	MobA MobL family protein
HKLHMGCA_01995	3.26e-94	-	-	-	-	-	-	-	-
HKLHMGCA_01996	6.32e-66	-	-	-	S	-	-	-	Cag pathogenicity island, type IV secretory system
HKLHMGCA_01997	8.94e-70	-	-	-	-	-	-	-	-
HKLHMGCA_01998	4.48e-152	-	-	-	-	-	-	-	-
HKLHMGCA_01999	0.0	traE	-	-	U	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_02000	2.05e-298	-	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HKLHMGCA_02001	1.59e-208	-	-	-	M	-	-	-	CHAP domain
HKLHMGCA_02002	2.17e-76	-	-	-	-	-	-	-	-
HKLHMGCA_02003	9.67e-59	-	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HKLHMGCA_02004	3.88e-87	-	-	-	-	-	-	-	-
HKLHMGCA_02005	1.07e-293	traK	-	-	U	ko:K03205	ko03070,map03070	ko00000,ko00001,ko00002,ko02044	TraM recognition site of TraD and TraG
HKLHMGCA_02007	6.64e-95	-	-	-	-	-	-	-	-
HKLHMGCA_02008	0.0	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKLHMGCA_02009	7.54e-44	-	-	-	-	-	-	-	-
HKLHMGCA_02010	4.39e-79	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_02011	3.04e-122	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKLHMGCA_02012	1.33e-87	-	-	-	-	-	-	-	-
HKLHMGCA_02014	1.78e-35	-	-	-	V	-	-	-	Abi-like protein
HKLHMGCA_02015	7.95e-66	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_02017	7.21e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKLHMGCA_02018	1.71e-302	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HKLHMGCA_02019	5.34e-107	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HKLHMGCA_02020	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HKLHMGCA_02021	6.3e-95	-	-	-	-	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	-
HKLHMGCA_02022	0.0	pacL	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	P-type ATPase
HKLHMGCA_02023	5.27e-197	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKLHMGCA_02024	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKLHMGCA_02025	3.99e-177	tagA	2.4.1.187	GT26	F	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKLHMGCA_02026	5.41e-160	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HKLHMGCA_02027	2.4e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKLHMGCA_02028	5.35e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKLHMGCA_02029	1.06e-195	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HKLHMGCA_02030	1.86e-246	ysdE	-	-	P	-	-	-	Citrate transporter
HKLHMGCA_02031	3.62e-211	pphA	3.1.3.16	-	T	ko:K07313	-	ko00000,ko01000	Calcineurin-like phosphoesterase
HKLHMGCA_02032	1.38e-71	-	-	-	S	-	-	-	Cupin domain
HKLHMGCA_02033	5.21e-65	-	-	-	S	-	-	-	Cupin 2, conserved barrel domain protein
HKLHMGCA_02036	8.34e-60	-	-	-	L	ko:K07482	-	ko00000	Integrase core domain
HKLHMGCA_02037	2.01e-132	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKLHMGCA_02038	0.0	ybeC	-	-	E	-	-	-	amino acid
HKLHMGCA_02040	6.61e-77	-	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_02041	1e-98	-	-	-	S	ko:K06889	-	ko00000	X-Pro dipeptidyl-peptidase (S15 family)
HKLHMGCA_02042	1.56e-56	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_02043	1.66e-214	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HKLHMGCA_02044	7.99e-92	-	-	-	-	-	-	-	-
HKLHMGCA_02045	6.54e-168	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_02046	7.62e-222	-	-	-	C	-	-	-	C4-dicarboxylate transmembrane transporter activity
HKLHMGCA_02047	2.15e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HKLHMGCA_02048	1.37e-119	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HKLHMGCA_02049	6.7e-102	yphH	-	-	S	-	-	-	Cupin domain
HKLHMGCA_02050	3.55e-79	-	-	-	I	-	-	-	sulfurtransferase activity
HKLHMGCA_02051	3.83e-178	gdh	1.1.1.47, 1.1.1.53	-	IQ	ko:K00034,ko:K00038	ko00030,ko00140,ko01100,ko01120,ko01200,map00030,map00140,map01100,map01120,map01200	ko00000,ko00001,ko01000	reductase
HKLHMGCA_02052	2.4e-151	-	-	-	GM	-	-	-	NAD(P)H-binding
HKLHMGCA_02053	2.31e-277	-	-	-	-	-	-	-	-
HKLHMGCA_02054	3.5e-308	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_02055	1.45e-97	-	-	-	V	ko:K06147,ko:K18892	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_02056	0.0	XK27_09600	-	-	V	ko:K06147,ko:K18891	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02057	3.1e-288	amd	-	-	E	-	-	-	Peptidase family M20/M25/M40
HKLHMGCA_02058	2.96e-209	yhxD	-	-	IQ	-	-	-	KR domain
HKLHMGCA_02060	1.97e-92	-	-	-	-	-	-	-	-
HKLHMGCA_02061	4.78e-183	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_02062	0.0	-	-	-	E	-	-	-	Amino Acid
HKLHMGCA_02063	1.67e-86	lysM	-	-	M	-	-	-	LysM domain
HKLHMGCA_02064	4.2e-286	dhaT	1.1.1.202	-	C	ko:K00086	ko00561,ko00640,map00561,map00640	ko00000,ko00001,ko01000	Dehydrogenase
HKLHMGCA_02065	6.8e-272	adhC	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
HKLHMGCA_02066	0.0	copA	3.6.3.3, 3.6.3.4, 3.6.3.5, 3.6.3.54	-	P	ko:K01533,ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HKLHMGCA_02067	1.49e-58	-	-	-	S	-	-	-	Cupredoxin-like domain
HKLHMGCA_02068	1.36e-84	-	-	-	S	-	-	-	Cupredoxin-like domain
HKLHMGCA_02069	6.46e-49	-	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HKLHMGCA_02070	4.73e-169	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKLHMGCA_02071	1.29e-31	-	3.1.4.17, 3.1.4.53	-	S	ko:K01120,ko:K03651	ko00230,ko02025,map00230,map02025	ko00000,ko00001,ko01000	Calcineurin-like phosphoesterase
HKLHMGCA_02072	2.8e-135	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_02073	9.76e-83	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	LrgA family
HKLHMGCA_02074	2.88e-164	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	LrgB-like family
HKLHMGCA_02075	3.84e-186	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HKLHMGCA_02076	4.22e-34	-	-	-	-	-	-	-	-
HKLHMGCA_02077	1.48e-152	yugP	-	-	S	ko:K06973	-	ko00000	Putative neutral zinc metallopeptidase
HKLHMGCA_02078	0.0	-	1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31	-	Q	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	ko00000,ko00001,ko01000	Flavin containing amine oxidoreductase
HKLHMGCA_02079	6.72e-209	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Squalene/phytoene synthase
HKLHMGCA_02080	4.68e-235	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HKLHMGCA_02081	1.01e-251	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HKLHMGCA_02082	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
HKLHMGCA_02083	2.05e-72	-	-	-	S	-	-	-	Enterocin A Immunity
HKLHMGCA_02084	3.66e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKLHMGCA_02085	0.0	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKLHMGCA_02086	4.17e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKLHMGCA_02087	6.97e-134	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKLHMGCA_02088	4.29e-33	amiF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Oligopeptide/dipeptide transporter, C-terminal region
HKLHMGCA_02089	1.84e-241	oppD	-	-	P	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HKLHMGCA_02090	2.53e-200	-	-	-	EP	ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKLHMGCA_02091	0.0	amiC	-	-	U	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_02092	0.0	amiA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding proteins, family 5 Middle
HKLHMGCA_02093	5.9e-187	ptp2	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HKLHMGCA_02094	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKLHMGCA_02096	1.08e-75	-	-	-	-	-	-	-	-
HKLHMGCA_02097	1.88e-63	-	-	-	K	-	-	-	DNA-binding transcription factor activity
HKLHMGCA_02098	3.12e-79	-	-	-	S	-	-	-	SnoaL-like domain
HKLHMGCA_02099	3.66e-74	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKLHMGCA_02100	2.88e-105	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HKLHMGCA_02101	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMGCA_02102	5.14e-216	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HKLHMGCA_02103	6.91e-234	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HKLHMGCA_02104	1.23e-62	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKLHMGCA_02105	4.75e-305	-	-	-	EGP	-	-	-	MFS transporter, metabolite H symporter (MHS) family protein
HKLHMGCA_02106	9.89e-199	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HKLHMGCA_02107	3.24e-222	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKLHMGCA_02108	9.33e-224	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKLHMGCA_02109	4.63e-123	-	-	-	L	-	-	-	Resolvase, N terminal domain
HKLHMGCA_02111	1.11e-50	-	-	-	L	ko:K07483	-	ko00000	Transposase
HKLHMGCA_02112	3.59e-51	-	-	-	L	-	-	-	4.5 Transposon and IS
HKLHMGCA_02113	5.61e-98	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_02114	2.47e-125	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HKLHMGCA_02115	9.58e-35	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HKLHMGCA_02116	1.86e-256	pkn2	-	-	KLT	-	-	-	Protein tyrosine kinase
HKLHMGCA_02117	3.32e-210	-	-	-	-	-	-	-	-
HKLHMGCA_02118	3.66e-295	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKLHMGCA_02119	2.92e-143	-	-	-	-	-	-	-	-
HKLHMGCA_02120	9.28e-271	xylR	-	-	GK	-	-	-	ROK family
HKLHMGCA_02121	1.6e-233	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKLHMGCA_02122	5.06e-168	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKLHMGCA_02123	6.79e-53	-	-	-	-	-	-	-	-
HKLHMGCA_02124	7.85e-114	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02125	2.5e-66	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKLHMGCA_02126	1.92e-115	-	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKLHMGCA_02127	2e-62	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_02128	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	C-terminus of AA_permease
HKLHMGCA_02130	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKLHMGCA_02131	1.07e-211	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHMGCA_02132	1.54e-228	ydbI	-	-	K	-	-	-	AI-2E family transporter
HKLHMGCA_02133	1.68e-276	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HKLHMGCA_02134	1.15e-77	-	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKLHMGCA_02135	1.97e-60	qacH	-	-	U	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HKLHMGCA_02136	2.94e-149	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HKLHMGCA_02137	7.27e-73	-	-	-	K	ko:K21903	-	ko00000,ko03000	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_02138	1.3e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HKLHMGCA_02139	6.74e-148	-	-	-	-	-	-	-	-
HKLHMGCA_02140	9.26e-230	-	-	-	S	-	-	-	MobA/MobL family
HKLHMGCA_02141	0.000891	-	-	-	S	-	-	-	Protein of unknown function (DUF3847)
HKLHMGCA_02142	2.4e-129	-	-	-	S	-	-	-	NgoFVII restriction endonuclease
HKLHMGCA_02144	4.87e-50	-	-	-	L	-	-	-	Transposase
HKLHMGCA_02145	5.57e-115	-	-	-	L	-	-	-	Transposase
HKLHMGCA_02146	1.57e-82	-	-	-	S	-	-	-	Initiator Replication protein
HKLHMGCA_02147	4.33e-09	-	-	-	S	-	-	-	Protein of unknown function, DUF536
HKLHMGCA_02148	1.72e-190	nlaXM	2.1.1.37	-	H	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	cytosine-specific methyltransferase
HKLHMGCA_02151	9.04e-78	yafQ	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
HKLHMGCA_02152	1.15e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HKLHMGCA_02153	2.65e-139	-	-	-	L	-	-	-	Integrase
HKLHMGCA_02154	3.95e-172	inlJ	-	-	M	-	-	-	MucBP domain
HKLHMGCA_02155	0.0	-	-	-	D	-	-	-	nuclear chromosome segregation
HKLHMGCA_02156	1.27e-109	-	-	-	K	-	-	-	MarR family
HKLHMGCA_02157	1.09e-56	-	-	-	-	-	-	-	-
HKLHMGCA_02158	1.28e-51	-	-	-	-	-	-	-	-
HKLHMGCA_02159	2.54e-289	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_02160	1.1e-06	-	-	-	K	ko:K07727	-	ko00000,ko03000	transcriptional regulator
HKLHMGCA_02162	3.96e-13	-	-	-	-	-	-	-	-
HKLHMGCA_02164	3.18e-41	-	-	-	-	-	-	-	-
HKLHMGCA_02165	9.72e-184	-	-	-	L	-	-	-	DNA replication protein
HKLHMGCA_02166	1.94e-257	-	-	-	S	-	-	-	Virulence-associated protein E
HKLHMGCA_02167	9.25e-65	-	-	-	S	-	-	-	Virulence-associated protein E
HKLHMGCA_02168	3.36e-96	-	-	-	-	-	-	-	-
HKLHMGCA_02170	8.91e-64	-	-	-	S	-	-	-	Head-tail joining protein
HKLHMGCA_02171	2.59e-89	-	-	-	L	-	-	-	HNH endonuclease
HKLHMGCA_02172	6.36e-108	-	-	-	L	-	-	-	overlaps another CDS with the same product name
HKLHMGCA_02173	0.0	terL	-	-	S	-	-	-	overlaps another CDS with the same product name
HKLHMGCA_02174	0.000349	-	-	-	-	-	-	-	-
HKLHMGCA_02175	1.84e-261	-	-	-	S	-	-	-	Phage portal protein
HKLHMGCA_02176	0.0	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HKLHMGCA_02177	1.62e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKLHMGCA_02178	7.78e-76	-	-	-	-	-	-	-	-
HKLHMGCA_02181	8.08e-40	-	-	-	-	-	-	-	-
HKLHMGCA_02184	2.96e-182	icaB	-	-	G	-	-	-	Polysaccharide deacetylase
HKLHMGCA_02185	5.63e-89	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKLHMGCA_02186	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02187	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HKLHMGCA_02188	5.37e-182	-	-	-	-	-	-	-	-
HKLHMGCA_02189	1.33e-77	-	-	-	-	-	-	-	-
HKLHMGCA_02190	1.9e-260	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HKLHMGCA_02191	2.1e-41	-	-	-	-	-	-	-	-
HKLHMGCA_02192	2.65e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HKLHMGCA_02193	4.95e-250	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HKLHMGCA_02194	1.83e-175	cobQ	-	-	S	ko:K07009	-	ko00000	glutamine amidotransferase
HKLHMGCA_02195	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HKLHMGCA_02196	5e-141	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HKLHMGCA_02197	1.88e-251	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKLHMGCA_02198	3.44e-204	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKLHMGCA_02199	7.28e-243	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKLHMGCA_02200	3.04e-297	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKLHMGCA_02201	7.81e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKLHMGCA_02202	1.44e-293	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HKLHMGCA_02203	6.85e-165	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HKLHMGCA_02204	3.66e-37	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLHMGCA_02205	7.68e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKLHMGCA_02206	5.83e-118	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKLHMGCA_02207	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKLHMGCA_02208	9.14e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKLHMGCA_02209	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKLHMGCA_02210	5.95e-74	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HKLHMGCA_02211	1.2e-314	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKLHMGCA_02212	1.68e-132	-	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKLHMGCA_02213	1.44e-230	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HKLHMGCA_02214	1.52e-57	ytjA	-	-	S	ko:K08998	-	ko00000	Could be involved in insertion of integral membrane proteins into the membrane
HKLHMGCA_02215	2.54e-46	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HKLHMGCA_02216	2.15e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HKLHMGCA_02217	3.2e-64	gcsH2	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	glycine cleavage
HKLHMGCA_02218	2.24e-239	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKLHMGCA_02219	2.1e-151	metI	-	-	U	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02220	3.03e-191	metQ	-	-	M	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HKLHMGCA_02221	3.34e-215	hicD3	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HKLHMGCA_02222	3.26e-227	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HKLHMGCA_02223	7.55e-242	-	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKLHMGCA_02224	3.78e-272	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HKLHMGCA_02225	0.0	glpQ3	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	Glycerophosphoryl diester phosphodiesterase family
HKLHMGCA_02226	4.7e-207	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_02227	8.1e-261	bla2	3.5.2.6	-	V	ko:K17836	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	Beta-lactamase enzyme family
HKLHMGCA_02228	2.37e-107	uspA	-	-	T	-	-	-	universal stress protein
HKLHMGCA_02229	1.34e-52	-	-	-	-	-	-	-	-
HKLHMGCA_02230	7.27e-303	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKLHMGCA_02231	0.0	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HKLHMGCA_02232	4.54e-59	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_02233	2.6e-141	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKLHMGCA_02234	4e-105	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKLHMGCA_02235	4.02e-145	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HKLHMGCA_02236	2.15e-137	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKLHMGCA_02237	5.28e-105	yebR	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HKLHMGCA_02238	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKLHMGCA_02240	2.59e-277	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HKLHMGCA_02241	7.66e-292	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKLHMGCA_02242	6.39e-299	gshF	6.3.2.2	-	H	ko:K01919,ko:K16786,ko:K16787	ko00270,ko00480,ko01100,ko02010,map00270,map00480,map01100,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the glutamate--cysteine ligase type 1 family
HKLHMGCA_02243	3.56e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKLHMGCA_02244	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKLHMGCA_02245	5.62e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKLHMGCA_02246	1.15e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HKLHMGCA_02247	1.74e-211	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HKLHMGCA_02248	3.76e-184	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HKLHMGCA_02249	9.47e-115	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HKLHMGCA_02250	3.81e-150	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKLHMGCA_02251	1.23e-187	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HKLHMGCA_02252	1.89e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02253	3.17e-149	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02254	2.61e-199	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HKLHMGCA_02255	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HKLHMGCA_02256	5.88e-295	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HKLHMGCA_02257	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HKLHMGCA_02258	4.71e-171	ymfM	-	-	S	ko:K15539	-	ko00000	Helix-turn-helix domain
HKLHMGCA_02259	1.92e-127	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKLHMGCA_02260	3.83e-295	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HKLHMGCA_02261	2.43e-264	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKLHMGCA_02262	6.57e-291	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HKLHMGCA_02263	6.18e-197	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	YmdB-like protein
HKLHMGCA_02264	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKLHMGCA_02265	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKLHMGCA_02267	4.56e-154	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKLHMGCA_02268	1.84e-261	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HKLHMGCA_02269	3.41e-187	-	3.1.3.102, 3.1.3.104, 3.1.3.23	-	G	ko:K07757,ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKLHMGCA_02270	3.21e-210	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_02271	7.15e-130	-	-	-	S	-	-	-	hydrolase
HKLHMGCA_02272	4.34e-48	-	-	-	S	-	-	-	hydrolase
HKLHMGCA_02273	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HKLHMGCA_02274	1.78e-264	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKLHMGCA_02276	2.2e-149	-	-	-	-	-	-	-	-
HKLHMGCA_02277	2.21e-137	-	-	-	-	-	-	-	-
HKLHMGCA_02278	4.26e-242	-	-	-	S	-	-	-	MobA/MobL family
HKLHMGCA_02282	2.69e-35	-	-	-	-	-	-	-	-
HKLHMGCA_02284	2.03e-182	-	-	-	-	-	-	-	-
HKLHMGCA_02287	3.56e-152	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKLHMGCA_02289	1.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKLHMGCA_02290	4.17e-55	-	-	-	K	-	-	-	prlF antitoxin for toxin YhaV_toxin
HKLHMGCA_02291	1.39e-118	XK27_09665	-	-	G	ko:K15640	-	ko00000	Phosphoglycerate mutase family
HKLHMGCA_02292	0.0	-	-	-	M	-	-	-	MucBP domain
HKLHMGCA_02293	1.42e-08	-	-	-	-	-	-	-	-
HKLHMGCA_02294	1.27e-115	-	-	-	S	-	-	-	AAA domain
HKLHMGCA_02295	1.97e-175	-	-	-	K	-	-	-	sequence-specific DNA binding
HKLHMGCA_02296	1.05e-121	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_02297	6.52e-219	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_02298	0.0	-	-	-	C	-	-	-	FMN_bind
HKLHMGCA_02300	1.9e-148	-	-	-	K	ko:K03489	-	ko00000,ko03000	UTRA
HKLHMGCA_02301	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_02302	7.36e-316	celD	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_02303	2.09e-85	-	-	-	-	-	-	-	-
HKLHMGCA_02304	5.15e-16	-	-	-	-	-	-	-	-
HKLHMGCA_02305	5.61e-54	pcaC	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKLHMGCA_02306	4.83e-31	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_02307	5.98e-85	-	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HKLHMGCA_02308	2.23e-279	-	-	-	S	-	-	-	Membrane
HKLHMGCA_02309	1.04e-59	-	-	-	S	-	-	-	Protein of unknown function (DUF3781)
HKLHMGCA_02310	1.31e-139	yoaZ	-	-	S	-	-	-	intracellular protease amidase
HKLHMGCA_02311	2.33e-56	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKLHMGCA_02313	1.23e-108	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKLHMGCA_02314	1.44e-33	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HKLHMGCA_02315	5.97e-61	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKLHMGCA_02316	0.000211	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HKLHMGCA_02317	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HKLHMGCA_02318	9.41e-280	-	-	-	S	-	-	-	PglZ domain
HKLHMGCA_02319	6.01e-200	-	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HKLHMGCA_02320	3.85e-81	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Glycerol-3-phosphate cytidylyltransferase
HKLHMGCA_02321	1.11e-07	-	-	-	C	-	-	-	Polysaccharide pyruvyl transferase
HKLHMGCA_02322	3.28e-49	-	-	-	M	-	-	-	PFAM Glycosyl transferase family 2
HKLHMGCA_02323	2.67e-35	-	-	-	M	-	-	-	O-Antigen ligase
HKLHMGCA_02324	1.37e-88	-	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKLHMGCA_02325	1.78e-87	cps4F	-	-	M	-	-	-	Glycosyl transferases group 1
HKLHMGCA_02326	1.05e-80	tuaA	-	-	M	-	-	-	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HKLHMGCA_02327	2.32e-06	-	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Male sterility protein
HKLHMGCA_02328	8.64e-40	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKLHMGCA_02329	1.36e-94	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKLHMGCA_02330	5.7e-146	epsB	-	-	M	-	-	-	biosynthesis protein
HKLHMGCA_02331	2e-234	-	-	-	V	-	-	-	Beta-lactamase
HKLHMGCA_02332	4.54e-54	-	-	-	-	-	-	-	-
HKLHMGCA_02334	8.83e-317	-	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_02335	5.61e-216	-	-	-	P	ko:K02077	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKLHMGCA_02336	4.08e-107	cvpA	-	-	S	-	-	-	Colicin V production protein
HKLHMGCA_02337	9.61e-84	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKLHMGCA_02338	1.59e-121	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HKLHMGCA_02339	1.04e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HKLHMGCA_02340	5.04e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HKLHMGCA_02341	3.59e-130	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HKLHMGCA_02342	1.37e-271	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HKLHMGCA_02343	1.31e-122	tag2	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HKLHMGCA_02344	1.31e-188	yisK	3.7.1.5, 4.1.1.68	-	Q	ko:K05921,ko:K16164	ko00350,ko01100,ko01120,ko01220,map00350,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Fumarylacetoacetate (FAA) hydrolase family
HKLHMGCA_02345	2.57e-212	yjdB	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKLHMGCA_02346	5.21e-62	-	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIA subunit
HKLHMGCA_02347	8.07e-182	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HKLHMGCA_02348	3.07e-84	-	-	-	S	-	-	-	Putative inner membrane protein (DUF1819)
HKLHMGCA_02349	1.15e-93	-	-	-	S	-	-	-	Domain of unknown function (DUF1788)
HKLHMGCA_02350	0.0	-	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HKLHMGCA_02352	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HKLHMGCA_02353	5.23e-77	yafQ	-	-	S	ko:K19157	-	ko00000,ko01000,ko02048	endonuclease activity
HKLHMGCA_02354	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HKLHMGCA_02355	1.26e-137	-	-	-	L	-	-	-	Integrase
HKLHMGCA_02356	1.58e-46	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HKLHMGCA_02357	1.53e-174	-	-	-	S	-	-	-	Protein of unknown function (DUF1524)
HKLHMGCA_02358	1.32e-20	lsgF	-	-	M	-	-	-	Glycosyltransferases involved in cell wall biogenesis
HKLHMGCA_02359	1.19e-159	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
HKLHMGCA_02360	9.36e-227	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
HKLHMGCA_02361	1.87e-172	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HKLHMGCA_02362	9.25e-161	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HKLHMGCA_02363	6.63e-161	epsB	-	-	M	-	-	-	biosynthesis protein
HKLHMGCA_02364	8.91e-161	-	-	-	S	-	-	-	Polysaccharide biosynthesis protein
HKLHMGCA_02365	3.92e-52	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKLHMGCA_02366	2.58e-71	-	-	-	S	-	-	-	Polysaccharide pyruvyl transferase
HKLHMGCA_02367	3.6e-211	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HKLHMGCA_02368	5.58e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF805)
HKLHMGCA_02369	5.28e-100	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKLHMGCA_02370	6.05e-108	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
HKLHMGCA_02371	2.05e-55	-	-	-	-	-	-	-	-
HKLHMGCA_02372	5.93e-60	ycnE	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HKLHMGCA_02373	9.96e-147	-	1.14.99.53	AA10	S	ko:K21713	-	ko00000,ko01000	Lytic polysaccharide mono-oxygenase, cellulose-degrading
HKLHMGCA_02374	1.05e-41	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKLHMGCA_02375	1.33e-273	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HKLHMGCA_02376	8.23e-39	-	-	-	-	-	-	-	-
HKLHMGCA_02377	1.48e-71	-	-	-	-	-	-	-	-
HKLHMGCA_02378	1.14e-193	-	-	-	O	-	-	-	Band 7 protein
HKLHMGCA_02379	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_02380	6.05e-121	-	-	-	K	-	-	-	transcriptional regulator
HKLHMGCA_02381	4.4e-246	rsgA_2	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKLHMGCA_02382	2.01e-113	ykhA	-	-	I	-	-	-	Thioesterase superfamily
HKLHMGCA_02383	7.52e-207	-	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_02384	1.48e-161	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKLHMGCA_02385	5.01e-129	-	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HKLHMGCA_02386	9.34e-175	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HKLHMGCA_02387	4.82e-179	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HKLHMGCA_02388	6.43e-203	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKLHMGCA_02389	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HKLHMGCA_02390	1.71e-91	fabZ2	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HKLHMGCA_02391	2.14e-95	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKLHMGCA_02392	7.64e-290	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKLHMGCA_02393	1.26e-162	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HKLHMGCA_02394	3.47e-215	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HKLHMGCA_02395	6.16e-48	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLHMGCA_02396	1.62e-229	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKLHMGCA_02397	8.55e-99	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKLHMGCA_02398	1.62e-229	yneE	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_02399	6.84e-186	yneD	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_02401	1.49e-77	-	-	-	S	-	-	-	Protein of unknown function (DUF1648)
HKLHMGCA_02402	1.26e-176	adhB	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKLHMGCA_02403	7.96e-273	hipO1	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	Peptidase family M20/M25/M40
HKLHMGCA_02404	1.62e-276	-	-	-	E	-	-	-	glutamate:sodium symporter activity
HKLHMGCA_02405	1.95e-88	ybbJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HKLHMGCA_02406	2.04e-226	-	1.6.5.5	-	C	ko:K00344	-	ko00000,ko01000	Zinc-binding dehydrogenase
HKLHMGCA_02407	5.89e-126	entB	-	-	Q	-	-	-	Isochorismatase family
HKLHMGCA_02408	4.82e-183	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKLHMGCA_02409	6.25e-288	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKLHMGCA_02410	1.57e-142	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HKLHMGCA_02411	1.2e-165	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HKLHMGCA_02412	6.03e-226	trpD	2.4.2.18, 4.1.3.27	-	F	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKLHMGCA_02413	8.08e-135	trpG	4.1.3.27	-	EH	ko:K01658	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Peptidase C26
HKLHMGCA_02414	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Anthranilate synthase component I, N terminal region
HKLHMGCA_02416	0.0	XK27_00765	-	-	-	ko:K01992	-	ko00000,ko00002,ko02000	-
HKLHMGCA_02417	2.05e-179	ecsA_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKLHMGCA_02418	9.06e-112	-	-	-	-	-	-	-	-
HKLHMGCA_02419	0.0	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HKLHMGCA_02420	3.2e-70	-	-	-	-	-	-	-	-
HKLHMGCA_02421	3.15e-78	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKLHMGCA_02422	1.57e-179	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HKLHMGCA_02423	6.42e-123	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKLHMGCA_02424	9.99e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HKLHMGCA_02425	1.6e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HKLHMGCA_02426	7.69e-300	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKLHMGCA_02427	1.46e-77	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKLHMGCA_02428	2.85e-293	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKLHMGCA_02429	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HKLHMGCA_02430	4.49e-167	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKLHMGCA_02431	3.33e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKLHMGCA_02432	2.17e-244	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKLHMGCA_02433	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKLHMGCA_02434	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HKLHMGCA_02435	7.09e-76	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKLHMGCA_02436	1.61e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HKLHMGCA_02437	7.5e-160	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HKLHMGCA_02438	3.16e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HKLHMGCA_02439	1.21e-209	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKLHMGCA_02440	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HKLHMGCA_02441	1.62e-173	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HKLHMGCA_02442	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKLHMGCA_02443	1.01e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKLHMGCA_02444	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKLHMGCA_02445	5.04e-278	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKLHMGCA_02446	3.93e-41	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKLHMGCA_02447	2.83e-144	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HKLHMGCA_02448	8.28e-73	-	-	-	-	-	-	-	-
HKLHMGCA_02449	1.36e-136	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HKLHMGCA_02450	3.8e-224	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKLHMGCA_02451	7.11e-135	opuCB	-	-	E	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02452	4.51e-284	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02453	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HKLHMGCA_02454	5.28e-100	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HKLHMGCA_02455	4.49e-192	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HKLHMGCA_02456	7.16e-201	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKLHMGCA_02457	7.55e-44	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHMGCA_02458	2.81e-313	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKLHMGCA_02459	4.82e-194	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKLHMGCA_02460	2.82e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKLHMGCA_02461	1.7e-96	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HKLHMGCA_02462	1.43e-129	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKLHMGCA_02463	3.49e-248	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HKLHMGCA_02464	2.33e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HKLHMGCA_02465	7.97e-71	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HKLHMGCA_02466	1.55e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HKLHMGCA_02467	3.32e-124	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_02468	9.81e-27	-	-	-	-	-	-	-	-
HKLHMGCA_02471	2.97e-41	-	-	-	-	-	-	-	-
HKLHMGCA_02472	3.11e-73	-	-	-	-	-	-	-	-
HKLHMGCA_02473	8.37e-126	-	-	-	S	-	-	-	Protein conserved in bacteria
HKLHMGCA_02474	1.34e-232	-	-	-	-	-	-	-	-
HKLHMGCA_02475	4.11e-206	-	-	-	-	-	-	-	-
HKLHMGCA_02476	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HKLHMGCA_02477	7.79e-85	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	Transcriptional regulator
HKLHMGCA_02478	3.8e-224	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKLHMGCA_02479	7.77e-179	glpQ	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HKLHMGCA_02480	1.44e-31	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HKLHMGCA_02481	1.15e-89	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HKLHMGCA_02482	1.62e-141	pepE	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HKLHMGCA_02483	2.6e-231	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HKLHMGCA_02484	6.33e-46	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HKLHMGCA_02485	3.52e-153	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HKLHMGCA_02486	9.29e-132	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKLHMGCA_02487	5.33e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKLHMGCA_02488	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HKLHMGCA_02489	0.0	-	-	-	S	-	-	-	membrane
HKLHMGCA_02490	2.5e-71	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HKLHMGCA_02491	2.33e-98	-	-	-	K	-	-	-	LytTr DNA-binding domain
HKLHMGCA_02492	3.78e-143	-	-	-	S	-	-	-	membrane
HKLHMGCA_02493	1.09e-105	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKLHMGCA_02494	7.5e-146	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HKLHMGCA_02495	6.11e-249	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKLHMGCA_02496	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLHMGCA_02497	6.88e-257	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKLHMGCA_02498	4.45e-83	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKLHMGCA_02499	1.72e-120	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHMGCA_02500	3.67e-178	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLHMGCA_02501	1.37e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HKLHMGCA_02502	1.4e-208	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKLHMGCA_02503	1.77e-122	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKLHMGCA_02504	9.59e-289	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKLHMGCA_02505	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HKLHMGCA_02506	1.93e-218	ubiA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HKLHMGCA_02507	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKLHMGCA_02508	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HKLHMGCA_02509	3.12e-311	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HKLHMGCA_02510	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKLHMGCA_02511	1.09e-223	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKLHMGCA_02512	3.06e-124	-	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKLHMGCA_02513	3.66e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HKLHMGCA_02514	3.04e-280	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HKLHMGCA_02515	3.3e-180	yqeM	-	-	Q	-	-	-	Methyltransferase
HKLHMGCA_02516	1.06e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKLHMGCA_02517	1.71e-149	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HKLHMGCA_02518	4.19e-153	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKLHMGCA_02519	2.19e-67	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HKLHMGCA_02520	3.81e-276	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HKLHMGCA_02521	1.34e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HKLHMGCA_02522	8.99e-114	-	-	-	-	-	-	-	-
HKLHMGCA_02523	9.51e-317	yijG	-	GT2	M	ko:K11936	ko02026,map02026	ko00000,ko00001,ko01000,ko01003,ko02000	Glycosyl transferase
HKLHMGCA_02524	2.39e-175	racD	5.1.1.13	-	G	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HKLHMGCA_02525	1.64e-83	ydeP	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HKLHMGCA_02526	1.18e-250	qor	1.1.1.1, 1.6.5.5	-	C	ko:K00001,ko:K00344	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HKLHMGCA_02527	7.03e-307	-	-	-	L	ko:K07478	-	ko00000	AAA C-terminal domain
HKLHMGCA_02528	4.59e-73	-	-	-	-	-	-	-	-
HKLHMGCA_02529	6.88e-73	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKLHMGCA_02530	6.92e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HKLHMGCA_02531	2.37e-109	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKLHMGCA_02532	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKLHMGCA_02533	3.5e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HKLHMGCA_02534	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HKLHMGCA_02535	1.58e-117	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKLHMGCA_02536	1.92e-133	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKLHMGCA_02537	3.19e-202	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKLHMGCA_02538	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKLHMGCA_02539	8.51e-155	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HKLHMGCA_02540	1.04e-141	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HKLHMGCA_02541	4.07e-60	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKLHMGCA_02542	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HKLHMGCA_02543	2.71e-108	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HKLHMGCA_02544	3.17e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKLHMGCA_02545	5.21e-311	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HKLHMGCA_02546	1.1e-184	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HKLHMGCA_02547	2.87e-47	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HKLHMGCA_02548	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HKLHMGCA_02549	3.04e-29	-	-	-	S	-	-	-	Virus attachment protein p12 family
HKLHMGCA_02550	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HKLHMGCA_02551	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HKLHMGCA_02552	1.29e-148	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKLHMGCA_02553	2.94e-71	ytzB	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HKLHMGCA_02554	4.7e-156	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKLHMGCA_02555	7.24e-197	ytmP	-	-	M	-	-	-	Choline/ethanolamine kinase
HKLHMGCA_02556	8.17e-285	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_02557	6.35e-174	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02558	3.6e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HKLHMGCA_02559	4.06e-65	-	-	-	-	-	-	-	-
HKLHMGCA_02560	1.09e-196	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKLHMGCA_02561	1.78e-153	draG	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HKLHMGCA_02562	5.76e-135	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_02563	2.82e-138	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_02564	9.64e-248	-	-	-	S	-	-	-	Fn3-like domain
HKLHMGCA_02565	1.65e-80	-	-	-	-	-	-	-	-
HKLHMGCA_02566	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_02567	5.19e-309	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKLHMGCA_02568	4.89e-146	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_02569	3.3e-151	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HKLHMGCA_02570	1.96e-137	-	-	-	-	-	-	-	-
HKLHMGCA_02571	5.21e-137	-	-	-	S	ko:K09962	-	ko00000	Nucleotidyltransferase
HKLHMGCA_02572	1.23e-106	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKLHMGCA_02573	4.9e-283	ribA	3.5.4.25, 4.1.99.12	-	H	ko:K02858,ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HKLHMGCA_02574	8.71e-111	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HKLHMGCA_02575	4.26e-218	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKLHMGCA_02576	1.7e-112	-	-	-	S	-	-	-	membrane
HKLHMGCA_02577	0.0	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HKLHMGCA_02578	4.4e-273	pbpX	-	-	V	-	-	-	Beta-lactamase
HKLHMGCA_02579	4.75e-267	mnaA	5.1.3.14	-	G	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKLHMGCA_02580	1.23e-200	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HKLHMGCA_02581	3.98e-169	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HKLHMGCA_02582	3.69e-277	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HKLHMGCA_02593	3.26e-119	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HKLHMGCA_02594	1.5e-235	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HKLHMGCA_02595	2.07e-123	-	-	-	-	-	-	-	-
HKLHMGCA_02596	1.58e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_02597	1.78e-201	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKLHMGCA_02598	1.24e-144	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKLHMGCA_02599	1.98e-184	lipA	-	-	I	-	-	-	Carboxylesterase family
HKLHMGCA_02600	1.21e-35	-	-	-	-	-	-	-	-
HKLHMGCA_02602	4.84e-38	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HKLHMGCA_02603	2.14e-33	mpr	-	-	E	-	-	-	Trypsin-like serine protease
HKLHMGCA_02604	1.09e-56	-	-	-	L	-	-	-	4.5 Transposon and IS
HKLHMGCA_02605	4.48e-78	-	-	-	S	-	-	-	Bacterial toxin of type II toxin-antitoxin system, YafQ
HKLHMGCA_02606	1.11e-59	-	-	-	D	ko:K19159	-	ko00000,ko02048	Antitoxin component of a toxin-antitoxin (TA) module
HKLHMGCA_02607	2.65e-139	-	-	-	L	-	-	-	Integrase
HKLHMGCA_02608	1.71e-38	-	-	-	-	-	-	-	-
HKLHMGCA_02609	8.02e-110	-	-	-	S	-	-	-	Pfam:DUF3816
HKLHMGCA_02610	3.47e-306	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKLHMGCA_02611	1.27e-143	-	-	-	-	-	-	-	-
HKLHMGCA_02612	1.08e-229	-	-	-	M	ko:K07273	-	ko00000	Glycosyl hydrolases family 25
HKLHMGCA_02613	9.06e-184	-	-	-	S	-	-	-	Peptidase_C39 like family
HKLHMGCA_02614	1.04e-120	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HKLHMGCA_02615	1.32e-116	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HKLHMGCA_02616	0.0	-	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	FtsX-like permease family
HKLHMGCA_02617	5.02e-227	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HKLHMGCA_02618	7.52e-315	-	-	-	EGP	-	-	-	Transporter, major facilitator family protein
HKLHMGCA_02619	8.24e-58	ywfI	-	-	S	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	Chlorite dismutase
HKLHMGCA_02620	5.46e-16	-	-	-	K	-	-	-	FRG
HKLHMGCA_02621	7.81e-247	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKLHMGCA_02622	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKLHMGCA_02623	5.83e-182	-	-	-	L	-	-	-	COG3547 Transposase and inactivated derivatives
HKLHMGCA_02624	1.57e-232	-	3.3.1.1	-	H	ko:K01251	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	adenosylhomocysteinase activity
HKLHMGCA_02625	2.44e-54	-	-	-	-	-	-	-	-
HKLHMGCA_02626	1.91e-34	-	-	-	-	-	-	-	-
HKLHMGCA_02627	1.78e-269	traA	-	-	L	-	-	-	MobA MobL family protein
HKLHMGCA_02628	4.96e-187	traA	-	-	L	-	-	-	MobA MobL family protein
HKLHMGCA_02629	5.35e-274	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HKLHMGCA_02630	7.66e-26	-	-	-	-	-	-	-	-
HKLHMGCA_02631	2.41e-219	-	-	-	L	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_02632	3.2e-76	-	-	-	T	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
HKLHMGCA_02633	2.22e-59	-	-	-	T	ko:K07172	-	ko00000,ko02048	Antidote-toxin recognition MazE, bacterial antitoxin
HKLHMGCA_02634	9.24e-140	-	-	-	L	-	-	-	Integrase
HKLHMGCA_02635	3.72e-21	-	-	-	-	-	-	-	-
HKLHMGCA_02636	5.09e-55	-	-	-	-	-	-	-	-
HKLHMGCA_02637	2.54e-42	cspA	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKLHMGCA_02638	2.77e-77	-	-	-	-	-	-	-	-
HKLHMGCA_02639	9.37e-198	-	-	-	L	-	-	-	Initiator Replication protein
HKLHMGCA_02640	9.99e-71	-	-	-	-	-	-	-	-
HKLHMGCA_02641	3.64e-149	-	-	-	S	-	-	-	Adenine-specific methyltransferase EcoRI
HKLHMGCA_02642	6.75e-210	-	-	-	V	-	-	-	Protein of unknown function DUF262
HKLHMGCA_02643	6.76e-17	-	-	-	L	-	-	-	Integrase
HKLHMGCA_02644	2.92e-38	-	-	-	-	-	-	-	-
HKLHMGCA_02645	1.71e-241	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKLHMGCA_02646	9.17e-126	gbuC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKLHMGCA_02647	1.14e-143	gbuB	-	-	E	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HKLHMGCA_02648	4.91e-233	gbuA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HKLHMGCA_02649	1.71e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HKLHMGCA_02650	1.05e-275	minJ	-	-	O	-	-	-	Domain present in PSD-95, Dlg, and ZO-1/2.
HKLHMGCA_02651	1.49e-170	phoP	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HKLHMGCA_02652	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HKLHMGCA_02653	6.91e-201	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKLHMGCA_02654	4.48e-206	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HKLHMGCA_02655	5.04e-200	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HKLHMGCA_02656	9.78e-190	pstB2	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLHMGCA_02657	2.69e-178	pstB1	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKLHMGCA_02658	1.55e-150	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HKLHMGCA_02659	2.78e-65	pspC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	positive regulation of macromolecule biosynthetic process
HKLHMGCA_02660	6.77e-70	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HKLHMGCA_02661	2.55e-225	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKLHMGCA_02662	3.62e-212	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKLHMGCA_02663	1.98e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HKLHMGCA_02664	1.13e-218	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HKLHMGCA_02665	3.69e-159	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKLHMGCA_02666	0.0	nox	-	-	C	-	-	-	NADH oxidase
HKLHMGCA_02667	8.65e-226	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKLHMGCA_02668	4.31e-141	yviA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HKLHMGCA_02669	7.54e-99	-	-	-	S	-	-	-	Protein of unknown function (DUF3290)
HKLHMGCA_02670	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HKLHMGCA_02671	2.4e-169	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKLHMGCA_02672	0.0	nox2	-	-	S	-	-	-	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HKLHMGCA_02673	1.89e-134	aad	3.4.13.22	-	E	ko:K08641	ko01502,ko02020,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HKLHMGCA_02674	5.33e-268	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HKLHMGCA_02675	3.85e-151	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HKLHMGCA_02676	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKLHMGCA_02677	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKLHMGCA_02678	2.21e-113	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKLHMGCA_02679	3.06e-301	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKLHMGCA_02680	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HKLHMGCA_02681	8.62e-114	-	-	-	S	-	-	-	Short repeat of unknown function (DUF308)
HKLHMGCA_02682	2e-206	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HKLHMGCA_02683	1.46e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HKLHMGCA_02684	1.21e-215	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HKLHMGCA_02685	0.0	oppA	-	-	E	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter, substratebinding protein
HKLHMGCA_02686	3.64e-224	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMGCA_02687	5.11e-133	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKLHMGCA_02689	1.14e-311	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	Sigma-54 factor, core binding domain
HKLHMGCA_02690	9.53e-241	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	Putative sugar-binding domain
HKLHMGCA_02691	2.02e-245	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKLHMGCA_02692	1.31e-285	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HKLHMGCA_02693	7.15e-179	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKLHMGCA_02694	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKLHMGCA_02695	2.42e-169	-	-	-	-	-	-	-	-
HKLHMGCA_02696	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HKLHMGCA_02697	1.76e-43	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HKLHMGCA_02698	6.35e-178	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Serine aminopeptidase, S33
HKLHMGCA_02699	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKLHMGCA_02700	9.78e-107	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HKLHMGCA_02701	0.0	-	-	-	M	-	-	-	Domain of unknown function (DUF5011)
HKLHMGCA_02702	0.0	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_02703	9.36e-171	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02704	7.98e-137	-	-	-	-	-	-	-	-
HKLHMGCA_02705	1.98e-199	ycsE	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HKLHMGCA_02706	5.71e-174	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKLHMGCA_02707	5e-227	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HKLHMGCA_02708	1.29e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HKLHMGCA_02709	2.52e-114	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_02710	2.41e-129	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKLHMGCA_02711	1.03e-197	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HKLHMGCA_02712	1.03e-211	ysjB	-	-	S	ko:K03810	-	ko00000	Oxidoreductase family, NAD-binding Rossmann fold
HKLHMGCA_02713	2.54e-213	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HKLHMGCA_02714	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HKLHMGCA_02715	3.07e-119	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_02716	5.68e-156	-	-	-	S	-	-	-	Protein of unknown function (DUF1361)
HKLHMGCA_02717	3.39e-191	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKLHMGCA_02718	2.18e-182	ybbR	-	-	S	-	-	-	YbbR-like protein
HKLHMGCA_02719	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKLHMGCA_02720	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKLHMGCA_02721	1.28e-157	-	-	-	T	-	-	-	EAL domain
HKLHMGCA_02722	3.27e-189	-	3.1.3.23	-	S	ko:K07757	-	ko00000,ko01000	Sucrose-6F-phosphate phosphohydrolase
HKLHMGCA_02723	1.21e-135	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_02724	4.87e-262	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HKLHMGCA_02725	3.38e-70	-	-	-	-	-	-	-	-
HKLHMGCA_02726	2.49e-95	-	-	-	-	-	-	-	-
HKLHMGCA_02727	2.87e-168	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HKLHMGCA_02728	3.51e-197	-	-	-	G	ko:K08217	-	br01600,ko00000,ko01504,ko02000	Transmembrane secretion effector
HKLHMGCA_02729	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKLHMGCA_02730	6.37e-186	-	-	-	-	-	-	-	-
HKLHMGCA_02732	5.45e-94	spx1	-	-	P	ko:K16509	-	ko00000	ArsC family
HKLHMGCA_02733	3.88e-46	-	-	-	-	-	-	-	-
HKLHMGCA_02734	2.08e-117	-	-	-	V	-	-	-	VanZ like family
HKLHMGCA_02735	1.24e-313	-	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_02736	4.45e-226	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKLHMGCA_02737	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HKLHMGCA_02738	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HKLHMGCA_02739	6.68e-197	licD	-	-	M	ko:K07271	-	ko00000,ko01000	LicD family
HKLHMGCA_02740	6.16e-107	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_02741	1.36e-27	-	-	-	-	-	-	-	-
HKLHMGCA_02742	1.79e-287	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HKLHMGCA_02743	0.0	pox1	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKLHMGCA_02744	1.06e-195	ribC1	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HKLHMGCA_02745	0.0	pox2	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HKLHMGCA_02746	3.45e-231	pepR	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HKLHMGCA_02747	1.23e-229	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKLHMGCA_02748	0.0	oatA	-	-	I	-	-	-	Acyltransferase
HKLHMGCA_02749	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HKLHMGCA_02750	1.89e-90	-	-	-	O	-	-	-	OsmC-like protein
HKLHMGCA_02751	1.09e-60	-	-	-	-	-	-	-	-
HKLHMGCA_02752	0.0	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HKLHMGCA_02753	6.12e-115	-	-	-	-	-	-	-	-
HKLHMGCA_02754	1.23e-189	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HKLHMGCA_02755	7.48e-96	-	-	-	F	-	-	-	Nudix hydrolase
HKLHMGCA_02756	1.48e-27	-	-	-	-	-	-	-	-
HKLHMGCA_02757	2.45e-134	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HKLHMGCA_02758	4.76e-105	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HKLHMGCA_02759	8.84e-18	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HKLHMGCA_02760	1.01e-188	-	-	-	-	-	-	-	-
HKLHMGCA_02761	6.94e-146	gph1	3.1.3.18	-	S	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	ko00000,ko00001,ko01000	HAD hydrolase, family IA, variant
HKLHMGCA_02762	7.9e-269	aspC	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HKLHMGCA_02763	1.03e-217	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKLHMGCA_02764	5.2e-54	-	-	-	-	-	-	-	-
HKLHMGCA_02766	2.3e-172	glnQ	-	-	E	ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02767	3.39e-190	glnH	-	-	ET	ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HKLHMGCA_02768	3.14e-140	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02769	1.27e-141	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02770	6.03e-109	-	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKLHMGCA_02771	7.77e-197	-	-	-	K	ko:K03488	-	ko00000,ko03000	CAT RNA binding domain
HKLHMGCA_02772	0.0	-	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKLHMGCA_02773	3.16e-182	-	3.5.1.105	-	G	ko:K03478	-	ko00000,ko01000	YdjC-like protein
HKLHMGCA_02774	0.0	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HKLHMGCA_02775	1.26e-95	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HKLHMGCA_02776	8.87e-191	-	-	-	S	-	-	-	Sulfite exporter TauE/SafE
HKLHMGCA_02777	8.83e-93	-	-	-	K	-	-	-	MarR family
HKLHMGCA_02778	3.22e-269	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKLHMGCA_02779	2.93e-109	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HKLHMGCA_02780	1.81e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_02781	1.7e-299	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKLHMGCA_02782	4.6e-102	rppH3	-	-	F	-	-	-	NUDIX domain
HKLHMGCA_02783	1.95e-61	sugE	-	-	U	ko:K11741	-	ko00000,ko02000	Multidrug resistance protein
HKLHMGCA_02784	1.61e-36	-	-	-	-	-	-	-	-
HKLHMGCA_02785	1.35e-165	pgm3	-	-	G	-	-	-	Phosphoglycerate mutase family
HKLHMGCA_02786	2.07e-161	gpm2	-	-	G	-	-	-	Phosphoglycerate mutase family
HKLHMGCA_02787	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HKLHMGCA_02788	4.16e-227	-	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HKLHMGCA_02789	1.11e-143	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HKLHMGCA_02790	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HKLHMGCA_02791	2.08e-211	fabK	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HKLHMGCA_02792	1.22e-227	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HKLHMGCA_02793	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HKLHMGCA_02795	0.0	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HKLHMGCA_02796	3.61e-76	yeeA	-	-	V	-	-	-	Type II restriction enzyme, methylase subunits
HKLHMGCA_02797	0.0	-	-	-	L	-	-	-	DEAD-like helicases superfamily
HKLHMGCA_02798	3.66e-162	yeeC	-	-	P	-	-	-	T5orf172
HKLHMGCA_02801	1.96e-81	-	-	-	L	-	-	-	AAA domain
HKLHMGCA_02802	6.18e-130	-	-	-	K	-	-	-	Transcriptional regulator, AbiEi antitoxin
HKLHMGCA_02803	9.75e-176	-	-	-	S	-	-	-	Nucleotidyl transferase AbiEii toxin, Type IV TA system
HKLHMGCA_02804	3.01e-38	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_02805	1.04e-69	-	-	-	-	-	-	-	-
HKLHMGCA_02806	8.89e-80	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_02807	1.57e-140	XK27_07075	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_02808	1.22e-242	-	-	-	S	-	-	-	Cysteine-rich secretory protein family
HKLHMGCA_02809	1.59e-64	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HKLHMGCA_02810	1.96e-117	-	-	-	D	-	-	-	nuclear chromosome segregation
HKLHMGCA_02811	6.46e-111	-	-	-	-	-	-	-	-
HKLHMGCA_02812	2.25e-204	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HKLHMGCA_02813	6.35e-69	-	-	-	-	-	-	-	-
HKLHMGCA_02814	8.49e-60	-	-	-	S	-	-	-	MORN repeat
HKLHMGCA_02815	0.0	XK27_09800	-	-	I	-	-	-	Acyltransferase family
HKLHMGCA_02816	1.81e-50	ydaS	-	-	S	-	-	-	Transglycosylase associated protein
HKLHMGCA_02817	1.95e-116	-	-	-	-	-	-	-	-
HKLHMGCA_02818	5.74e-32	-	-	-	-	-	-	-	-
HKLHMGCA_02819	1.1e-93	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKLHMGCA_02820	1.04e-94	asp2	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HKLHMGCA_02821	5.35e-65	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HKLHMGCA_02824	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HKLHMGCA_02825	1.5e-194	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HKLHMGCA_02828	4.58e-230	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_02830	2.15e-189	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_02831	0.0	-	-	-	LV	-	-	-	Eco57I restriction-modification methylase
HKLHMGCA_02832	7.54e-130	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
HKLHMGCA_02833	0.0	-	2.7.7.49	-	L	ko:K00986	-	ko00000,ko01000	PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HKLHMGCA_02834	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HKLHMGCA_02835	3.43e-58	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HKLHMGCA_02836	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HKLHMGCA_02837	2.12e-115	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HKLHMGCA_02838	9.1e-206	XK27_10395	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKLHMGCA_02841	3.61e-246	mob	-	-	D	-	-	-	Plasmid recombination enzyme
HKLHMGCA_02842	1.57e-213	-	-	-	L	-	-	-	Replication protein
HKLHMGCA_02844	1.25e-93	-	-	-	-	-	-	-	-
HKLHMGCA_02845	1.85e-82	-	-	-	-	-	-	-	-
HKLHMGCA_02846	5.73e-221	-	-	-	S	-	-	-	Virulence-associated protein E
HKLHMGCA_02847	1.84e-31	-	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HKLHMGCA_02848	5.76e-105	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HKLHMGCA_02849	1.65e-110	iolG	1.1.1.18, 1.1.1.369	-	G	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)
HKLHMGCA_02850	8.02e-18	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HKLHMGCA_02851	1.35e-55	-	-	-	S	-	-	-	COG NOG38524 non supervised orthologous group
HKLHMGCA_02852	1.46e-92	-	-	-	-	-	-	-	-
HKLHMGCA_02853	7.26e-80	-	-	-	-	-	-	-	-
HKLHMGCA_02854	3.21e-172	-	-	-	S	-	-	-	Virulence-associated protein E
HKLHMGCA_02855	1.95e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HKLHMGCA_02856	3.82e-188	-	-	-	KT	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_02857	3.41e-295	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKLHMGCA_02858	1.86e-123	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HKLHMGCA_02859	1.4e-239	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02860	7.14e-157	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02861	2.27e-116	-	-	-	T	ko:K16923	-	ko00000,ko00002,ko02000	phosphorelay sensor kinase activity
HKLHMGCA_02862	8.13e-238	iunH3	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Inosine-uridine preferring nucleoside hydrolase
HKLHMGCA_02863	1.39e-124	ywjB	-	-	H	-	-	-	RibD C-terminal domain
HKLHMGCA_02864	8.02e-258	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKLHMGCA_02865	9.01e-155	-	-	-	S	-	-	-	Membrane
HKLHMGCA_02866	3.49e-198	mleP3	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HKLHMGCA_02867	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Fumarase C C-terminus
HKLHMGCA_02868	3.04e-261	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HKLHMGCA_02869	1.99e-160	-	3.8.1.2	-	S	ko:K01560	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKLHMGCA_02870	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKLHMGCA_02871	2.33e-103	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKLHMGCA_02872	7.96e-127	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKLHMGCA_02873	4.38e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HKLHMGCA_02874	1.19e-193	rlrG	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HKLHMGCA_02875	0.0	tagE5	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HKLHMGCA_02876	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HKLHMGCA_02878	9.92e-88	-	-	-	M	-	-	-	LysM domain
HKLHMGCA_02879	1.6e-119	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Methyltransferase
HKLHMGCA_02880	9.97e-214	natA	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02881	7.88e-269	natB	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HKLHMGCA_02882	6.27e-166	-	-	-	S	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HKLHMGCA_02883	4.72e-72	cmd	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Carboxymuconolactone decarboxylase family
HKLHMGCA_02884	4.77e-100	yphH	-	-	S	-	-	-	Cupin domain
HKLHMGCA_02885	5.19e-103	-	-	-	K	-	-	-	transcriptional regulator, MerR family
HKLHMGCA_02886	1.46e-299	dapE	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HKLHMGCA_02887	0.0	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HKLHMGCA_02888	1.74e-156	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_02890	1.19e-150	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKLHMGCA_02891	3.18e-141	thgA3	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HKLHMGCA_02892	1.03e-150	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HKLHMGCA_02894	4.86e-111	-	-	-	-	-	-	-	-
HKLHMGCA_02895	1.04e-110	yvbK	-	-	K	-	-	-	GNAT family
HKLHMGCA_02896	9.76e-50	-	-	-	-	-	-	-	-
HKLHMGCA_02897	2.81e-64	-	-	-	-	-	-	-	-
HKLHMGCA_02898	7.44e-143	pgm8	-	-	G	-	-	-	Histidine phosphatase superfamily (branch 1)
HKLHMGCA_02899	6.09e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HKLHMGCA_02900	6.13e-200	-	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_02901	1.52e-135	-	-	-	GM	-	-	-	NAD(P)H-binding
HKLHMGCA_02902	1.66e-247	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HKLHMGCA_02903	1.18e-193	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HKLHMGCA_02904	1.28e-45	-	-	-	-	-	-	-	-
HKLHMGCA_02905	2.1e-99	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKLHMGCA_02906	2.97e-124	maa	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose O-acetyltransferase
HKLHMGCA_02907	5.89e-161	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HKLHMGCA_02908	2.31e-79	-	-	-	-	-	-	-	-
HKLHMGCA_02909	5.29e-131	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HKLHMGCA_02910	2.33e-283	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HKLHMGCA_02911	1.07e-131	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HKLHMGCA_02912	1.8e-249	-	-	-	C	-	-	-	Aldo/keto reductase family
HKLHMGCA_02914	0.0	mdlB	-	-	V	ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_02915	0.0	mdlA	-	-	V	ko:K06148,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_02916	6.27e-316	-	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_02920	1.03e-314	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HKLHMGCA_02921	3.01e-124	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HKLHMGCA_02922	6.88e-71	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_02923	4.88e-196	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HKLHMGCA_02924	1.34e-132	yokL3	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HKLHMGCA_02925	1.24e-125	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKLHMGCA_02926	1.38e-168	-	-	-	M	-	-	-	Phosphotransferase enzyme family
HKLHMGCA_02927	3.18e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_02928	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HKLHMGCA_02929	1.9e-189	-	3.1.3.102, 3.1.3.104	-	S	ko:K20861	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HKLHMGCA_02930	0.0	-	-	-	S	-	-	-	Predicted membrane protein (DUF2207)
HKLHMGCA_02931	0.0	uvrA3	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	excinuclease ABC
HKLHMGCA_02932	9.48e-265	-	-	-	EGP	-	-	-	Major facilitator Superfamily
HKLHMGCA_02933	7.97e-222	ropB	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_02934	2.33e-296	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	Vacuole effluxer Atg22 like
HKLHMGCA_02935	0.0	npp	-	-	S	-	-	-	type I phosphodiesterase nucleotide pyrophosphatase
HKLHMGCA_02936	2.85e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKLHMGCA_02937	6.11e-169	treR	-	-	K	ko:K03486	-	ko00000,ko03000	UTRA
HKLHMGCA_02938	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_02939	2e-52	-	-	-	S	-	-	-	Cytochrome B5
HKLHMGCA_02940	8.68e-118	pts21A	-	-	G	ko:K02755	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKLHMGCA_02941	1.11e-65	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HKLHMGCA_02942	5.08e-194	-	-	-	T	-	-	-	Diguanylate cyclase, GGDEF domain
HKLHMGCA_02943	1.63e-162	-	-	-	T	-	-	-	Putative diguanylate phosphodiesterase
HKLHMGCA_02944	3.83e-135	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HKLHMGCA_02945	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HKLHMGCA_02946	1.56e-108	-	-	-	-	-	-	-	-
HKLHMGCA_02947	6.98e-95	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HKLHMGCA_02948	3.08e-241	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLHMGCA_02949	1.26e-245	dus	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKLHMGCA_02950	7.16e-30	-	-	-	-	-	-	-	-
HKLHMGCA_02951	1.84e-134	-	-	-	-	-	-	-	-
HKLHMGCA_02952	3.46e-210	-	-	-	K	-	-	-	LysR substrate binding domain
HKLHMGCA_02953	4.34e-314	-	-	-	P	-	-	-	Sodium:sulfate symporter transmembrane region
HKLHMGCA_02954	0.0	-	4.1.1.98	-	H	ko:K03182	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HKLHMGCA_02955	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HKLHMGCA_02956	1.61e-183	-	-	-	S	-	-	-	zinc-ribbon domain
HKLHMGCA_02958	4.29e-50	-	-	-	-	-	-	-	-
HKLHMGCA_02959	1.48e-171	-	-	-	S	ko:K06889	-	ko00000	Alpha/beta hydrolase family
HKLHMGCA_02960	1.93e-230	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HKLHMGCA_02961	0.0	-	-	-	I	-	-	-	acetylesterase activity
HKLHMGCA_02962	6.55e-295	-	-	-	M	-	-	-	Collagen binding domain
HKLHMGCA_02963	8.08e-205	yicL	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_02964	3.03e-166	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HKLHMGCA_02965	1.44e-226	-	4.1.1.52	-	S	ko:K22213	-	ko00000,ko01000	Amidohydrolase
HKLHMGCA_02966	4.68e-141	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HKLHMGCA_02967	1.85e-51	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HKLHMGCA_02968	4.54e-208	ypbG	2.7.1.2	-	GK	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	ROK family
HKLHMGCA_02969	0.0	ybfG	-	-	M	-	-	-	peptidoglycan-binding domain-containing protein
HKLHMGCA_02970	9.86e-117	-	-	-	-	-	-	-	-
HKLHMGCA_02971	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HKLHMGCA_02972	7.39e-121	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HKLHMGCA_02973	5.85e-204	ccpB	-	-	K	-	-	-	lacI family
HKLHMGCA_02974	2.21e-154	yceE	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HKLHMGCA_02975	3.29e-153	ydgI3	-	-	C	-	-	-	Nitroreductase family
HKLHMGCA_02976	0.0	nagE	2.7.1.193, 2.7.1.199, 2.7.1.208	-	G	ko:K02777,ko:K02802,ko:K02803,ko:K02804,ko:K20107,ko:K20108,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system, EIIB
HKLHMGCA_02977	4.21e-150	-	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HKLHMGCA_02978	1.01e-198	WQ51_06230	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HKLHMGCA_02979	5.98e-217	XK27_00670	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HKLHMGCA_02980	0.0	-	-	-	-	-	-	-	-
HKLHMGCA_02981	4.71e-81	-	-	-	-	-	-	-	-
HKLHMGCA_02982	9.55e-243	-	-	-	S	-	-	-	Cell surface protein
HKLHMGCA_02983	1.27e-137	-	-	-	S	-	-	-	WxL domain surface cell wall-binding
HKLHMGCA_02984	5.06e-82	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKLHMGCA_02985	1.09e-42	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HKLHMGCA_02986	2.78e-158	livF	-	-	E	ko:K01996	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter
HKLHMGCA_02987	1.74e-178	livG	-	-	E	ko:K01995	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid ATP-binding cassette transporter
HKLHMGCA_02988	1.61e-193	livM	-	-	E	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKLHMGCA_02989	9.73e-197	livH	-	-	U	ko:K01997	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Branched-chain amino acid transport system / permease component
HKLHMGCA_02990	1.04e-269	livJ	-	-	E	ko:K01999	ko02010,ko02024,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HKLHMGCA_02992	1.15e-43	-	-	-	-	-	-	-	-
HKLHMGCA_02993	6.9e-168	zmp3	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKLHMGCA_02994	2.88e-106	gtcA3	-	-	S	-	-	-	GtrA-like protein
HKLHMGCA_02995	3.35e-157	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_02996	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HKLHMGCA_02997	1.18e-94	usp2	-	-	T	-	-	-	Belongs to the universal stress protein A family
HKLHMGCA_02998	7.03e-62	-	-	-	-	-	-	-	-
HKLHMGCA_02999	1.81e-150	-	-	-	S	-	-	-	SNARE associated Golgi protein
HKLHMGCA_03000	8.58e-65	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HKLHMGCA_03001	7.89e-124	-	-	-	P	-	-	-	Cadmium resistance transporter
HKLHMGCA_03002	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HKLHMGCA_03003	0.0	-	-	-	P	-	-	-	Concanavalin A-like lectin/glucanases superfamily
HKLHMGCA_03004	2.03e-84	-	-	-	-	-	-	-	-
HKLHMGCA_03005	1.93e-205	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HKLHMGCA_03006	1.21e-73	-	-	-	-	-	-	-	-
HKLHMGCA_03007	1.24e-194	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_03008	3.91e-100	pts23A	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HKLHMGCA_03009	7.47e-70	ptcB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
HKLHMGCA_03010	0.0	pts23C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKLHMGCA_03011	0.0	pbg6	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HKLHMGCA_03012	7.8e-238	-	-	-	GM	-	-	-	Male sterility protein
HKLHMGCA_03013	2.1e-99	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_03014	2.18e-99	-	-	-	M	-	-	-	LysM domain
HKLHMGCA_03015	1.44e-128	-	-	-	M	-	-	-	Lysin motif
HKLHMGCA_03016	1.4e-138	-	-	-	S	-	-	-	SdpI/YhfL protein family
HKLHMGCA_03017	1.58e-72	nudA	-	-	S	-	-	-	ASCH
HKLHMGCA_03018	2.74e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKLHMGCA_03019	1.41e-118	-	-	-	-	-	-	-	-
HKLHMGCA_03020	6.68e-156	tag	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Methyladenine glycosylase
HKLHMGCA_03021	1.22e-272	-	-	-	T	-	-	-	diguanylate cyclase
HKLHMGCA_03022	4.65e-91	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HKLHMGCA_03023	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HKLHMGCA_03024	1.43e-57	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKLHMGCA_03025	6.88e-151	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
HKLHMGCA_03026	2.66e-38	-	-	-	-	-	-	-	-
HKLHMGCA_03027	1e-62	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HKLHMGCA_03028	1.58e-47	-	-	-	C	-	-	-	Flavodoxin
HKLHMGCA_03029	1.2e-208	-	-	-	S	ko:K06889	-	ko00000	Hydrolases of the alpha beta superfamily
HKLHMGCA_03030	2.62e-173	-	-	-	C	-	-	-	Aldo/keto reductase family
HKLHMGCA_03031	5.31e-102	-	-	-	GM	-	-	-	NmrA-like family
HKLHMGCA_03032	1.91e-44	-	-	-	C	-	-	-	Flavodoxin
HKLHMGCA_03033	0.0	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HKLHMGCA_03034	4.86e-84	-	-	-	S	-	-	-	Protein of unknown function (DUF1398)
HKLHMGCA_03035	2.55e-65	-	-	-	-	-	-	-	-
HKLHMGCA_03036	7.21e-35	-	-	-	-	-	-	-	-
HKLHMGCA_03037	7.03e-158	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HKLHMGCA_03038	1.19e-252	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-type multidrug transport system, permease component
HKLHMGCA_03039	8.66e-152	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_03040	1.33e-149	ypgQ	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HKLHMGCA_03041	3.77e-278	-	-	-	EGP	-	-	-	Major Facilitator
HKLHMGCA_03042	4.02e-304	xylP	-	-	G	-	-	-	MFS/sugar transport protein
HKLHMGCA_03043	8.99e-133	-	-	-	-	-	-	-	-
HKLHMGCA_03044	2.78e-75	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HKLHMGCA_03046	9.92e-122	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKLHMGCA_03047	7.29e-171	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
HKLHMGCA_03048	1.91e-38	-	-	-	-	-	-	-	-
HKLHMGCA_03049	2.58e-68	-	-	-	-	-	-	-	-
HKLHMGCA_03050	1.15e-05	-	-	-	-	-	-	-	-
HKLHMGCA_03051	1.87e-54	-	-	-	-	-	-	-	-
HKLHMGCA_03052	2.9e-139	-	-	-	-	-	-	-	-
HKLHMGCA_03053	7.62e-97	-	-	-	-	-	-	-	-
HKLHMGCA_03055	2.03e-31	-	-	-	S	-	-	-	Family of unknown function (DUF5388)
HKLHMGCA_03056	1.18e-184	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKLHMGCA_03057	7.1e-126	soj	-	-	D	-	-	-	CobQ CobB MinD ParA nucleotide binding domain protein
HKLHMGCA_03059	3.41e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKLHMGCA_03060	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKLHMGCA_03061	1.27e-129	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKLHMGCA_03062	2.94e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HKLHMGCA_03063	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HKLHMGCA_03064	3.7e-149	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HKLHMGCA_03065	1.09e-197	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HKLHMGCA_03066	7.29e-247	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	transferase
HKLHMGCA_03067	0.0	ydaO	-	-	E	-	-	-	amino acid
HKLHMGCA_03068	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKLHMGCA_03069	9.82e-55	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKLHMGCA_03070	2.38e-140	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HKLHMGCA_03071	3.67e-154	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKLHMGCA_03072	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HKLHMGCA_03073	3.62e-249	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKLHMGCA_03074	5.74e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKLHMGCA_03075	4.66e-131	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HKLHMGCA_03076	6.84e-167	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HKLHMGCA_03077	3.46e-242	phnD	-	-	P	ko:K02044	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter
HKLHMGCA_03078	9.33e-177	phnC	3.6.3.28	-	P	ko:K02041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HKLHMGCA_03079	6.51e-178	phnE2	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphonate ABC transporter permease
HKLHMGCA_03080	1.11e-182	phnE1	-	-	U	ko:K02042	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HKLHMGCA_03081	1.97e-187	phnX	3.11.1.1	-	E	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the HAD-like hydrolase superfamily. PhnX family
HKLHMGCA_03082	2.09e-267	phnW	2.6.1.37	-	E	ko:K03430	ko00440,ko01100,ko01120,map00440,map01100,map01120	ko00000,ko00001,ko01000,ko01007	Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HKLHMGCA_03083	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HKLHMGCA_03084	3.17e-191	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HKLHMGCA_03085	1.26e-211	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKLHMGCA_03086	8.46e-77	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HKLHMGCA_03087	2.33e-239	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HKLHMGCA_03088	1.39e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HKLHMGCA_03089	1.28e-152	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKLHMGCA_03090	1.01e-51	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HKLHMGCA_03091	6.22e-140	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKLHMGCA_03092	2.05e-62	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKLHMGCA_03093	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKLHMGCA_03094	7.57e-119	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKLHMGCA_03095	6.7e-141	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HKLHMGCA_03096	8.42e-50	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HKLHMGCA_03097	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMGCA_03098	2.47e-253	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKLHMGCA_03099	5.82e-141	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HKLHMGCA_03100	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKLHMGCA_03101	2.07e-87	-	-	-	L	-	-	-	nuclease
HKLHMGCA_03102	1.01e-226	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HKLHMGCA_03103	5.6e-25	chpA	-	-	T	ko:K07171,ko:K18841	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HKLHMGCA_03104	4.3e-35	-	-	-	T	ko:K07172	-	ko00000,ko02048	SpoVT / AbrB like domain
HKLHMGCA_03105	6.18e-54	-	-	-	S	-	-	-	Bacteriophage holin
HKLHMGCA_03106	3.48e-59	-	-	-	-	-	-	-	-
HKLHMGCA_03107	1.5e-256	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKLHMGCA_03108	8.33e-34	-	-	-	-	-	-	-	-
HKLHMGCA_03109	1.05e-56	-	-	-	LM	-	-	-	DNA recombination
HKLHMGCA_03113	1.67e-126	-	-	-	S	-	-	-	Domain of unknown function (DUF2479)
HKLHMGCA_03114	3.83e-213	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HKLHMGCA_03115	0.0	-	-	-	M	-	-	-	Prophage endopeptidase tail
HKLHMGCA_03116	1.38e-172	-	-	-	S	-	-	-	phage tail
HKLHMGCA_03117	0.0	-	-	-	D	-	-	-	domain protein
HKLHMGCA_03119	3.57e-109	-	-	-	S	-	-	-	Phage tail assembly chaperone protein, TAC
HKLHMGCA_03120	6.46e-117	-	-	-	-	-	-	-	-
HKLHMGCA_03121	1.37e-81	-	-	-	-	-	-	-	-
HKLHMGCA_03122	4.59e-121	-	-	-	-	-	-	-	-
HKLHMGCA_03123	5.25e-65	-	-	-	-	-	-	-	-
HKLHMGCA_03124	8.92e-75	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HKLHMGCA_03125	6.73e-245	gpG	-	-	-	-	-	-	-
HKLHMGCA_03126	5.68e-105	-	-	-	S	-	-	-	Domain of unknown function (DUF4355)
HKLHMGCA_03127	4.06e-216	-	-	-	S	-	-	-	Phage Mu protein F like protein
HKLHMGCA_03128	0.0	-	-	-	S	-	-	-	Phage portal protein, SPP1 Gp6-like
HKLHMGCA_03129	0.0	-	-	-	S	ko:K06909	-	ko00000	Phage terminase, large subunit
HKLHMGCA_03130	1.58e-112	-	-	-	L	ko:K07474	-	ko00000	Terminase small subunit
HKLHMGCA_03131	1.1e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2829)
HKLHMGCA_03132	1.25e-86	-	-	-	K	-	-	-	IrrE N-terminal-like domain
HKLHMGCA_03133	2.3e-174	-	-	-	-	-	-	-	-
HKLHMGCA_03138	1.34e-28	-	-	-	S	-	-	-	YopX protein
HKLHMGCA_03140	7.79e-85	-	-	-	L	-	-	-	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HKLHMGCA_03141	3.55e-110	-	-	-	-	-	-	-	-
HKLHMGCA_03143	3.44e-64	-	-	-	K	ko:K07741	-	ko00000	AntA/AntB antirepressor
HKLHMGCA_03144	3.24e-67	-	-	-	-	-	-	-	-
HKLHMGCA_03145	1.65e-213	-	-	-	L	-	-	-	Domain of unknown function (DUF4373)
HKLHMGCA_03146	9.87e-79	-	-	-	-	-	-	-	-
HKLHMGCA_03147	8e-70	-	-	-	S	-	-	-	Bacteriophage Mu Gam like protein
HKLHMGCA_03149	1.22e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1351)
HKLHMGCA_03152	4.59e-121	-	-	-	-	-	-	-	-
HKLHMGCA_03155	2.57e-07	-	-	-	K	-	-	-	Transcriptional
HKLHMGCA_03156	1.61e-81	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_03157	4.71e-98	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HKLHMGCA_03158	1.94e-40	-	-	-	S	-	-	-	TerB N-terminal domain
HKLHMGCA_03162	6.3e-293	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HKLHMGCA_03164	2.76e-74	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKLHMGCA_03165	3.72e-105	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKLHMGCA_03166	2.69e-158	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKLHMGCA_03167	9.76e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKLHMGCA_03168	2.81e-202	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HKLHMGCA_03169	1.89e-128	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HKLHMGCA_03170	1e-39	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKLHMGCA_03171	4.55e-31	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HKLHMGCA_03172	1.12e-130	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Sigma-70 region 2
HKLHMGCA_03173	3.4e-126	yacP	-	-	S	ko:K06962	-	ko00000	YacP-like NYN domain
HKLHMGCA_03174	1.49e-177	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKLHMGCA_03175	1.35e-92	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKLHMGCA_03176	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HKLHMGCA_03177	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKLHMGCA_03178	4.91e-265	yacL	-	-	S	-	-	-	domain protein
HKLHMGCA_03179	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKLHMGCA_03180	9.43e-127	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HKLHMGCA_03181	5.96e-69	yjdJ	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HKLHMGCA_03182	1.62e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HKLHMGCA_03183	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HKLHMGCA_03184	1.85e-156	zmp2	-	-	O	-	-	-	Zinc-dependent metalloprotease
HKLHMGCA_03185	1.91e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HKLHMGCA_03186	8.57e-227	-	-	-	EG	-	-	-	EamA-like transporter family
HKLHMGCA_03187	7.53e-215	mleP2	-	-	S	ko:K07088	-	ko00000	Transporter, auxin efflux carrier (AEC) family protein
HKLHMGCA_03188	6.55e-234	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKLHMGCA_03189	1.23e-177	accA1	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HKLHMGCA_03190	3.66e-184	accD1	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKLHMGCA_03191	1.7e-315	accC1	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase C-terminal domain
HKLHMGCA_03192	9.24e-85	accB1	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin-requiring enzyme
HKLHMGCA_03193	3.67e-228	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKLHMGCA_03194	4.5e-113	manX	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKLHMGCA_03195	7.19e-94	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HKLHMGCA_03196	0.0	levR	-	-	K	-	-	-	Sigma-54 interaction domain
HKLHMGCA_03197	9.05e-85	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HKLHMGCA_03198	8.89e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HKLHMGCA_03199	2.43e-174	manM	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HKLHMGCA_03200	2.63e-217	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HKLHMGCA_03201	2.27e-197	-	-	-	G	-	-	-	Peptidase_C39 like family
HKLHMGCA_03202	6.5e-85	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HKLHMGCA_03203	1.24e-37	hol	-	-	S	-	-	-	Bacteriophage holin
HKLHMGCA_03205	3.35e-30	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	O-acyltransferase activity
HKLHMGCA_03206	1.9e-153	-	-	-	S	-	-	-	Plasmid replication protein
HKLHMGCA_03208	1.65e-101	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HKLHMGCA_03210	8.03e-28	-	-	-	-	-	-	-	-
HKLHMGCA_03211	1.08e-172	-	-	-	L	-	-	-	Primase C terminal 1 (PriCT-1)
HKLHMGCA_03212	2.71e-38	-	-	-	-	-	-	-	-
HKLHMGCA_03215	2.62e-192	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKLHMGCA_03216	8.53e-152	-	-	-	L	-	-	-	Helix-turn-helix domain
HKLHMGCA_03217	7e-208	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HKLHMGCA_03218	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HKLHMGCA_03219	9.11e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HKLHMGCA_03220	1.23e-58	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HKLHMGCA_03221	5.31e-242	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HKLHMGCA_03222	3.88e-264	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HKLHMGCA_03223	8.69e-230	citR	-	-	K	-	-	-	sugar-binding domain protein
HKLHMGCA_03224	0.0	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKLHMGCA_03225	9.2e-215	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HKLHMGCA_03226	1.18e-66	-	-	-	-	-	-	-	-
HKLHMGCA_03227	1.73e-221	mntA	-	-	P	ko:K19975,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HKLHMGCA_03228	3.54e-180	mtsB	-	-	U	ko:K19972,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC 3 transport family
HKLHMGCA_03229	8.31e-170	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HKLHMGCA_03230	1.57e-196	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HKLHMGCA_03231	1.28e-253	-	-	-	K	-	-	-	Helix-turn-helix domain
HKLHMGCA_03232	5.21e-226	ttdA	4.2.1.32	-	C	ko:K03779	ko00630,map00630	ko00000,ko00001,ko01000	Fumarate hydratase (Fumerase)
HKLHMGCA_03233	1.41e-147	-	4.2.1.2, 4.2.1.32	-	C	ko:K01676,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible hydration of fumarate to (S)- malate
HKLHMGCA_03234	4.33e-69	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HKLHMGCA_03235	0.0	-	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HKLHMGCA_03236	1.23e-251	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKLHMGCA_03237	3.3e-235	aroF	2.5.1.54	-	E	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	DAHP synthetase I family
HKLHMGCA_03238	2.25e-209	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKLHMGCA_03239	0.0	tkt2	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKLHMGCA_03240	1.35e-261	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HKLHMGCA_03241	2.46e-235	-	-	-	S	-	-	-	Membrane
HKLHMGCA_03242	4.92e-209	yitS	-	-	S	-	-	-	Uncharacterised protein, DegV family COG1307
HKLHMGCA_03243	8.98e-86	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HKLHMGCA_03244	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKLHMGCA_03245	3.06e-194	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKLHMGCA_03246	2.39e-184	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHMGCA_03247	2.01e-211	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHMGCA_03248	1.98e-197	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKLHMGCA_03249	1.07e-264	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HKLHMGCA_03250	3.19e-194	-	-	-	S	-	-	-	FMN_bind
HKLHMGCA_03251	0.0	ndh	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HKLHMGCA_03252	5.37e-112	-	-	-	S	-	-	-	NusG domain II
HKLHMGCA_03253	1.41e-122	hepA	2.5.1.30	-	S	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase component I
HKLHMGCA_03254	1.02e-233	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HKLHMGCA_03255	7.76e-81	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HKLHMGCA_03256	2.19e-220	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHMGCA_03257	7.71e-82	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKLHMGCA_03258	9.65e-79	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKLHMGCA_03259	9.87e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKLHMGCA_03260	1.84e-160	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKLHMGCA_03261	5.95e-300	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKLHMGCA_03262	1.32e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HKLHMGCA_03263	8.44e-34	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HKLHMGCA_03264	5.32e-109	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKLHMGCA_03265	1.75e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKLHMGCA_03266	2.14e-123	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKLHMGCA_03267	4.99e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKLHMGCA_03268	3.53e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKLHMGCA_03269	1.38e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKLHMGCA_03270	2.98e-78	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKLHMGCA_03271	1.96e-54	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKLHMGCA_03272	1.11e-33	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HKLHMGCA_03273	8.29e-100	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKLHMGCA_03274	5.46e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKLHMGCA_03275	3.59e-69	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKLHMGCA_03276	1.85e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKLHMGCA_03277	6.61e-193	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKLHMGCA_03278	2.27e-59	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKLHMGCA_03279	9.83e-141	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HKLHMGCA_03280	4.34e-145	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKLHMGCA_03281	4.46e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HKLHMGCA_03282	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKLHMGCA_03283	1.19e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKLHMGCA_03284	4.19e-92	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKLHMGCA_03285	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHMGCA_03286	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKLHMGCA_03287	1.16e-140	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HKLHMGCA_03288	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HKLHMGCA_03289	9.78e-102	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HKLHMGCA_03297	1.62e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKLHMGCA_03298	1.11e-148	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HKLHMGCA_03299	1.29e-153	dacB	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HKLHMGCA_03300	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HKLHMGCA_03301	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HKLHMGCA_03302	9.82e-118	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_03303	7.14e-128	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HKLHMGCA_03304	3.88e-198	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKLHMGCA_03305	4.15e-153	-	-	-	I	-	-	-	phosphatase
HKLHMGCA_03306	2.34e-242	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HKLHMGCA_03307	4.49e-99	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HKLHMGCA_03308	4.6e-169	-	-	-	S	-	-	-	Putative threonine/serine exporter
HKLHMGCA_03309	1.78e-42	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HKLHMGCA_03310	2.94e-155	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HKLHMGCA_03311	1.36e-77	-	-	-	-	-	-	-	-
HKLHMGCA_03312	7.79e-112	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKLHMGCA_03313	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HKLHMGCA_03314	2.72e-152	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HKLHMGCA_03315	1.46e-170	-	-	-	-	-	-	-	-
HKLHMGCA_03316	1.75e-47	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HKLHMGCA_03317	1.43e-155	azlC	-	-	E	-	-	-	branched-chain amino acid
HKLHMGCA_03318	2.41e-66	azlD	-	-	S	-	-	-	Branched-chain amino acid transport protein (AzlD)
HKLHMGCA_03319	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HKLHMGCA_03320	2.42e-281	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Amino acid kinase family
HKLHMGCA_03321	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKLHMGCA_03322	0.0	xylP2	-	-	G	-	-	-	symporter
HKLHMGCA_03323	2.98e-246	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HKLHMGCA_03324	2.74e-63	-	-	-	-	-	-	-	-
HKLHMGCA_03325	1.5e-156	gpm5	-	-	G	-	-	-	Phosphoglycerate mutase family
HKLHMGCA_03326	4.97e-132	-	-	-	K	-	-	-	FR47-like protein
HKLHMGCA_03327	8.44e-163	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HKLHMGCA_03328	1.89e-277	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HKLHMGCA_03329	1.86e-242	-	-	-	-	-	-	-	-
HKLHMGCA_03330	2.91e-179	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HKLHMGCA_03331	5.06e-68	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HKLHMGCA_03332	9.95e-211	rluD2	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HKLHMGCA_03333	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HKLHMGCA_03334	4.95e-44	-	-	-	L	-	-	-	leucine-zipper of insertion element IS481
HKLHMGCA_03335	9.05e-55	-	-	-	-	-	-	-	-
HKLHMGCA_03336	1.32e-290	-	-	-	L	-	-	-	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HKLHMGCA_03337	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HKLHMGCA_03338	3.39e-255	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HKLHMGCA_03339	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HKLHMGCA_03340	4.71e-149	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKLHMGCA_03341	4.13e-104	-	-	-	K	-	-	-	Transcriptional regulator
HKLHMGCA_03343	1.43e-71	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKLHMGCA_03344	4.49e-74	-	-	-	L	-	-	-	Transposase DDE domain
HKLHMGCA_03345	3.07e-203	is18	-	-	L	-	-	-	Integrase core domain
HKLHMGCA_03347	1.59e-107	-	2.7.13.3	-	T	ko:K07706	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HKLHMGCA_03348	2.06e-234	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
HKLHMGCA_03349	1.02e-161	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
HKLHMGCA_03350	5.8e-46	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HKLHMGCA_03351	5.81e-88	-	-	-	L	-	-	-	Transposase