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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
MEDFPHPC_00001	4.21e-20	-	-	-	S	-	-	-	KAP family P-loop domain
MEDFPHPC_00002	2.08e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MEDFPHPC_00004	7.47e-148	-	-	-	K	-	-	-	Transcriptional regulator
MEDFPHPC_00005	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
MEDFPHPC_00006	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
MEDFPHPC_00007	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
MEDFPHPC_00008	7.04e-218	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00009	5.11e-259	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MEDFPHPC_00010	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
MEDFPHPC_00011	8.07e-91	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MEDFPHPC_00012	2.34e-205	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MEDFPHPC_00013	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEDFPHPC_00014	3.3e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MEDFPHPC_00015	7.72e-198	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MEDFPHPC_00016	6.61e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
MEDFPHPC_00017	5.75e-98	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MEDFPHPC_00018	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
MEDFPHPC_00020	4.19e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
MEDFPHPC_00021	3.16e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MEDFPHPC_00022	3.29e-279	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MEDFPHPC_00023	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MEDFPHPC_00024	7.64e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MEDFPHPC_00025	2.05e-311	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MEDFPHPC_00026	1.54e-165	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
MEDFPHPC_00027	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
MEDFPHPC_00028	1.53e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MEDFPHPC_00029	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
MEDFPHPC_00030	9.12e-161	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
MEDFPHPC_00031	1e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
MEDFPHPC_00032	1.18e-74	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
MEDFPHPC_00033	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
MEDFPHPC_00034	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MEDFPHPC_00035	7.34e-214	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MEDFPHPC_00036	6.72e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEDFPHPC_00037	1.62e-165	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MEDFPHPC_00038	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
MEDFPHPC_00039	9.19e-254	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MEDFPHPC_00040	1.72e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MEDFPHPC_00041	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MEDFPHPC_00042	1.25e-285	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_00044	1.24e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00045	3.58e-132	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00046	1.44e-144	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00047	3.17e-65	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00048	0.0	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MEDFPHPC_00049	3.65e-204	-	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MEDFPHPC_00050	1.33e-123	-	-	-	-	-	-	-	-
MEDFPHPC_00051	3.41e-168	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
MEDFPHPC_00052	3.3e-204	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MEDFPHPC_00053	6.8e-196	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MEDFPHPC_00054	1.74e-195	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MEDFPHPC_00055	1.05e-175	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MEDFPHPC_00056	2.78e-158	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
MEDFPHPC_00057	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
MEDFPHPC_00058	9.17e-54	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
MEDFPHPC_00059	1.78e-113	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MEDFPHPC_00060	2.22e-182	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
MEDFPHPC_00061	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
MEDFPHPC_00062	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MEDFPHPC_00063	3.44e-237	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_00064	2.89e-141	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
MEDFPHPC_00065	9.39e-230	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
MEDFPHPC_00066	1.89e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEDFPHPC_00067	4.19e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MEDFPHPC_00068	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MEDFPHPC_00069	8.81e-211	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MEDFPHPC_00070	2.9e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00071	1.26e-17	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00072	1.04e-150	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00073	2.71e-215	-	1.1.1.29	-	CH	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_00074	2.28e-32	mleP	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MEDFPHPC_00075	1.95e-45	ydaT	-	-	-	-	-	-	-
MEDFPHPC_00077	1.32e-268	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00078	3.36e-42	tnp1216	-	-	L	ko:K07498	-	ko00000	DDE domain
MEDFPHPC_00079	9.49e-62	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEDFPHPC_00080	1.85e-76	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00081	1.74e-235	ysdE	-	-	P	-	-	-	Citrate transporter
MEDFPHPC_00082	5.53e-242	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00083	3.62e-22	ytgB	-	-	S	-	-	-	Transglycosylase associated protein
MEDFPHPC_00084	1.7e-54	-	-	-	L	ko:K07483	-	ko00000	Homeodomain-like domain
MEDFPHPC_00085	1.49e-33	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00086	1.25e-140	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00087	0.0	cidC	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
MEDFPHPC_00088	0.0	gshR3	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Glutathione reductase
MEDFPHPC_00090	0.0	mycA	4.2.1.53	-	S	ko:K10254	-	ko00000,ko01000	MCRA family
MEDFPHPC_00091	1.2e-31	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_00092	4.67e-55	-	-	-	S	-	-	-	Protein of unknown function (DUF998)
MEDFPHPC_00093	2.79e-97	tnpR	-	-	L	-	-	-	Resolvase, N terminal domain
MEDFPHPC_00094	1.08e-112	-	-	-	K	-	-	-	FR47-like protein
MEDFPHPC_00096	7.93e-290	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00097	5.93e-195	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
MEDFPHPC_00098	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
MEDFPHPC_00099	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_00100	7.65e-261	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_00101	6.74e-118	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
MEDFPHPC_00102	2.42e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
MEDFPHPC_00103	1.07e-129	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
MEDFPHPC_00104	5.62e-120	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00105	5.07e-261	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MEDFPHPC_00106	5.8e-271	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
MEDFPHPC_00107	2.59e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
MEDFPHPC_00108	3.08e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
MEDFPHPC_00109	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
MEDFPHPC_00110	1.91e-114	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
MEDFPHPC_00111	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
MEDFPHPC_00112	4.14e-173	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
MEDFPHPC_00113	8.55e-187	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
MEDFPHPC_00114	5.75e-244	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
MEDFPHPC_00115	2.7e-204	-	-	-	EG	-	-	-	EamA-like transporter family
MEDFPHPC_00116	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
MEDFPHPC_00117	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MEDFPHPC_00118	1.07e-141	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
MEDFPHPC_00119	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MEDFPHPC_00120	0.0	fusA1	-	-	J	-	-	-	elongation factor G
MEDFPHPC_00121	6.2e-271	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
MEDFPHPC_00122	1.65e-106	-	-	-	F	-	-	-	Hydrolase, NUDIX family
MEDFPHPC_00123	2.59e-278	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
MEDFPHPC_00124	1.08e-242	arcT	-	-	E	-	-	-	Dipeptidase
MEDFPHPC_00125	3.51e-253	arcD	-	-	S	-	-	-	C4-dicarboxylate anaerobic carrier
MEDFPHPC_00126	1.06e-225	nylA	3.5.1.4	-	J	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	ko00000,ko00001,ko01000	Belongs to the amidase family
MEDFPHPC_00127	1.67e-57	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00128	3.64e-217	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00129	1.75e-97	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_00130	4.58e-150	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MEDFPHPC_00131	5.91e-200	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MEDFPHPC_00132	2.34e-140	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
MEDFPHPC_00133	6.26e-92	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
MEDFPHPC_00134	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
MEDFPHPC_00135	5.58e-94	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MEDFPHPC_00136	2.47e-221	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MEDFPHPC_00137	1.99e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
MEDFPHPC_00138	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MEDFPHPC_00139	5.06e-151	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
MEDFPHPC_00140	3.86e-209	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
MEDFPHPC_00141	1.8e-151	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00142	6.85e-86	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00143	2.74e-157	butA	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MEDFPHPC_00144	4.53e-238	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_00145	3.97e-34	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MEDFPHPC_00146	2.8e-259	-	-	-	F	ko:K03458	-	ko00000	Permease
MEDFPHPC_00147	7.32e-205	-	-	-	H	-	-	-	Acyl-protein synthetase, LuxE
MEDFPHPC_00148	9.24e-249	-	-	-	C	-	-	-	Acyl-CoA reductase (LuxC)
MEDFPHPC_00149	7.11e-144	-	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	KR domain
MEDFPHPC_00150	2.62e-76	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00151	4.17e-135	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
MEDFPHPC_00152	2.35e-303	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
MEDFPHPC_00153	3.47e-197	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
MEDFPHPC_00154	5.11e-232	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_00155	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
MEDFPHPC_00156	6.96e-206	-	-	-	S	-	-	-	EDD domain protein, DegV family
MEDFPHPC_00157	9.35e-128	-	-	-	-	-	-	-	-
MEDFPHPC_00158	3.78e-167	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
MEDFPHPC_00159	2.5e-153	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MEDFPHPC_00160	1.19e-144	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
MEDFPHPC_00161	9.48e-125	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MEDFPHPC_00162	9.87e-203	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MEDFPHPC_00163	1.02e-297	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
MEDFPHPC_00164	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
MEDFPHPC_00165	2.99e-57	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
MEDFPHPC_00166	5.16e-57	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
MEDFPHPC_00167	1.48e-42	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
MEDFPHPC_00168	1.34e-229	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
MEDFPHPC_00169	2.59e-229	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
MEDFPHPC_00170	2.74e-272	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MEDFPHPC_00171	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
MEDFPHPC_00172	1.67e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MEDFPHPC_00173	2.65e-269	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MEDFPHPC_00174	3.56e-128	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
MEDFPHPC_00175	1.27e-271	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
MEDFPHPC_00176	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MEDFPHPC_00177	7e-269	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MEDFPHPC_00178	5.06e-201	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
MEDFPHPC_00179	1.21e-211	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
MEDFPHPC_00180	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEDFPHPC_00181	2.07e-298	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MEDFPHPC_00182	1.05e-199	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MEDFPHPC_00183	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MEDFPHPC_00184	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
MEDFPHPC_00185	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
MEDFPHPC_00186	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MEDFPHPC_00188	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
MEDFPHPC_00189	1.05e-15	-	-	-	-	-	-	-	-
MEDFPHPC_00190	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
MEDFPHPC_00192	5.36e-299	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
MEDFPHPC_00193	7.28e-08	-	-	-	S	-	-	-	Alpha beta hydrolase
MEDFPHPC_00194	4.84e-168	-	-	-	S	-	-	-	Alpha beta hydrolase
MEDFPHPC_00195	5.98e-33	-	-	-	GM	-	-	-	NAD(P)H-binding
MEDFPHPC_00196	1.73e-101	-	-	-	GM	-	-	-	NAD(P)H-binding
MEDFPHPC_00197	4.15e-192	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MEDFPHPC_00199	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MEDFPHPC_00201	1.25e-62	-	-	-	G	-	-	-	Major Facilitator Superfamily
MEDFPHPC_00202	1.86e-147	-	-	-	G	-	-	-	Major Facilitator Superfamily
MEDFPHPC_00203	2.48e-13	aroH	5.4.99.5	-	E	ko:K04516	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Chorismate mutase
MEDFPHPC_00204	1.35e-246	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MEDFPHPC_00205	1.56e-131	-	-	-	-	-	-	-	-
MEDFPHPC_00206	4.22e-85	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEDFPHPC_00207	7.35e-77	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEDFPHPC_00208	1.43e-79	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MEDFPHPC_00209	2.08e-244	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
MEDFPHPC_00210	1.11e-112	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MEDFPHPC_00211	1.32e-271	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
MEDFPHPC_00212	1.63e-233	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_00213	3.65e-226	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
MEDFPHPC_00214	5.22e-200	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
MEDFPHPC_00215	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
MEDFPHPC_00216	0.0	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
MEDFPHPC_00217	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
MEDFPHPC_00218	2.3e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
MEDFPHPC_00219	2.64e-303	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
MEDFPHPC_00220	3.25e-292	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MEDFPHPC_00221	5.04e-109	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
MEDFPHPC_00222	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
MEDFPHPC_00223	1.09e-231	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MEDFPHPC_00224	4.53e-238	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_00225	1.37e-182	-	-	-	EG	-	-	-	EamA-like transporter family
MEDFPHPC_00226	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
MEDFPHPC_00227	1.04e-26	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
MEDFPHPC_00228	2.98e-71	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MEDFPHPC_00229	4.44e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
MEDFPHPC_00230	2.6e-183	fecE	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MEDFPHPC_00231	1.03e-218	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEDFPHPC_00232	7.91e-95	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
MEDFPHPC_00233	2.34e-47	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
MEDFPHPC_00234	1.67e-249	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MEDFPHPC_00235	2.31e-278	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
MEDFPHPC_00236	2.36e-77	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
MEDFPHPC_00237	2.74e-209	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
MEDFPHPC_00238	4.15e-171	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MEDFPHPC_00240	9.19e-213	-	-	-	H	-	-	-	geranyltranstransferase activity
MEDFPHPC_00241	1.56e-231	-	-	-	-	-	-	-	-
MEDFPHPC_00242	1.11e-52	-	-	-	-	-	-	-	-
MEDFPHPC_00243	4.49e-151	nreC	-	-	K	ko:K07696	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	PFAM regulatory protein LuxR
MEDFPHPC_00244	1.48e-233	nreB	2.7.13.3	-	F	ko:K07683	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Sensor histidine kinase
MEDFPHPC_00245	4.11e-100	nreA	-	-	T	ko:K10851	ko02020,map02020	ko00000,ko00001	GAF domain
MEDFPHPC_00246	6.94e-54	-	-	-	-	-	-	-	-
MEDFPHPC_00247	2.3e-124	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MEDFPHPC_00248	5.2e-106	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MEDFPHPC_00249	4.27e-293	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	MoeA N-terminal region (domain I and II)
MEDFPHPC_00250	1.04e-110	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
MEDFPHPC_00251	1.71e-241	moeB	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
MEDFPHPC_00252	0.0	narZ	1.7.5.1	-	C	ko:K00370	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MEDFPHPC_00253	0.0	-	1.7.5.1	-	C	ko:K00371	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	4Fe-4S dicluster domain
MEDFPHPC_00254	2.15e-132	narJ	-	-	C	ko:K00373	ko02020,map02020	ko00000,ko00001	Nitrate reductase delta subunit
MEDFPHPC_00255	6.13e-164	narI	1.7.5.1	-	C	ko:K00374	ko00910,ko01120,ko02020,map00910,map01120,map02020	ko00000,ko00001,ko00002,ko01000	Nitrate reductase
MEDFPHPC_00256	1.77e-234	-	-	-	-	-	-	-	-
MEDFPHPC_00257	8.01e-97	-	-	-	-	-	-	-	-
MEDFPHPC_00258	2.24e-61	-	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
MEDFPHPC_00259	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MEDFPHPC_00260	5.45e-121	-	-	-	V	-	-	-	VanZ like family
MEDFPHPC_00261	5.71e-282	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
MEDFPHPC_00262	5.33e-79	-	-	-	-	-	-	-	-
MEDFPHPC_00263	5.43e-231	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEDFPHPC_00264	2.34e-301	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
MEDFPHPC_00265	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
MEDFPHPC_00266	1.12e-217	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
MEDFPHPC_00267	1.12e-21	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_00268	5.92e-34	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MEDFPHPC_00269	1.35e-70	-	-	-	L	-	-	-	Transposase
MEDFPHPC_00270	2.41e-280	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MEDFPHPC_00271	3.29e-108	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00272	5.56e-105	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00273	1.72e-63	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
MEDFPHPC_00275	5.72e-104	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
MEDFPHPC_00276	1.31e-53	-	-	-	-	-	-	-	-
MEDFPHPC_00277	4.24e-218	-	-	-	GK	-	-	-	ROK family
MEDFPHPC_00278	1.38e-162	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
MEDFPHPC_00279	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
MEDFPHPC_00280	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MEDFPHPC_00281	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MEDFPHPC_00282	1e-71	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEDFPHPC_00283	9e-72	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MEDFPHPC_00284	6.04e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00285	5.18e-126	-	-	-	K	-	-	-	DNA-templated transcription, initiation
MEDFPHPC_00287	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MEDFPHPC_00288	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
MEDFPHPC_00289	5.26e-148	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00290	2.55e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
MEDFPHPC_00291	8.5e-116	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
MEDFPHPC_00292	1.62e-56	yrfB	-	-	C	-	-	-	NADH:flavin oxidoreductase / NADH oxidase family
MEDFPHPC_00293	2.68e-71	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
MEDFPHPC_00294	5.41e-274	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MEDFPHPC_00295	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
MEDFPHPC_00296	1.77e-280	aadAT	-	-	EK	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	ko00000,ko00001,ko01000	Aminotransferase, class I
MEDFPHPC_00297	4.57e-32	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MEDFPHPC_00298	1.09e-136	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MEDFPHPC_00299	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEDFPHPC_00301	6.33e-278	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
MEDFPHPC_00303	2.55e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
MEDFPHPC_00304	2.81e-125	-	-	-	K	-	-	-	Virulence activator alpha C-term
MEDFPHPC_00305	1.37e-103	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
MEDFPHPC_00306	4.96e-24	-	-	-	S	-	-	-	SNARE associated Golgi protein
MEDFPHPC_00307	4.47e-30	-	-	-	S	-	-	-	SNARE associated Golgi protein
MEDFPHPC_00308	1.3e-302	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
MEDFPHPC_00309	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEDFPHPC_00311	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MEDFPHPC_00312	1.07e-101	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MEDFPHPC_00314	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MEDFPHPC_00315	8.78e-206	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
MEDFPHPC_00316	3.19e-208	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MEDFPHPC_00317	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDFPHPC_00318	1.7e-203	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
MEDFPHPC_00320	3.1e-288	-	-	-	-	-	-	-	-
MEDFPHPC_00321	6.24e-245	flp	-	-	V	-	-	-	Beta-lactamase
MEDFPHPC_00322	4.77e-116	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
MEDFPHPC_00323	7.03e-30	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
MEDFPHPC_00324	2.46e-234	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
MEDFPHPC_00325	5.4e-273	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
MEDFPHPC_00326	3.88e-204	rssA	-	-	S	-	-	-	Phospholipase, patatin family
MEDFPHPC_00327	3.05e-211	-	-	-	K	-	-	-	LysR substrate binding domain
MEDFPHPC_00328	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MEDFPHPC_00329	1.78e-108	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
MEDFPHPC_00330	4.52e-141	yicL	-	-	EG	-	-	-	EamA-like transporter family
MEDFPHPC_00331	1.26e-82	-	-	-	-	-	-	-	-
MEDFPHPC_00332	6.64e-42	-	-	-	-	-	-	-	-
MEDFPHPC_00333	2.29e-88	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
MEDFPHPC_00334	2.01e-225	-	-	-	K	-	-	-	WYL domain
MEDFPHPC_00335	2.12e-308	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
MEDFPHPC_00336	6.72e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
MEDFPHPC_00337	2.86e-215	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MEDFPHPC_00338	2.55e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MEDFPHPC_00339	3.29e-259	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
MEDFPHPC_00340	2.3e-275	-	-	-	G	-	-	-	Transporter, major facilitator family protein
MEDFPHPC_00341	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MEDFPHPC_00342	1.71e-201	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MEDFPHPC_00343	4.32e-71	yuxO	-	-	Q	-	-	-	Thioesterase superfamily
MEDFPHPC_00344	2.92e-134	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00345	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00346	1.26e-17	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00347	8.6e-97	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00348	6.06e-117	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00349	3.79e-272	msmK2	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
MEDFPHPC_00350	1.01e-312	-	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
MEDFPHPC_00351	8.34e-194	-	-	-	U	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEDFPHPC_00352	1.37e-181	-	-	-	U	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEDFPHPC_00353	1.35e-116	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00354	1.55e-159	-	-	-	EGP	ko:K08164	-	ko00000,ko02000	Transporter
MEDFPHPC_00355	3.27e-108	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
MEDFPHPC_00356	1.05e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_00357	4.59e-68	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00358	1.93e-43	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
MEDFPHPC_00359	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00360	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00361	3.4e-124	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MEDFPHPC_00362	1.6e-24	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MEDFPHPC_00363	1.51e-88	-	-	-	I	-	-	-	Alpha/beta hydrolase family
MEDFPHPC_00364	1.54e-138	-	-	-	L	-	-	-	Integrase
MEDFPHPC_00365	3.74e-58	-	-	-	K	-	-	-	transcriptional regulator
MEDFPHPC_00366	6.02e-101	-	-	-	GM	-	-	-	NmrA-like family
MEDFPHPC_00367	4.97e-35	-	-	-	C	-	-	-	Flavodoxin
MEDFPHPC_00368	4.67e-58	adh2	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MEDFPHPC_00369	1.82e-32	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MEDFPHPC_00370	1.15e-79	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
MEDFPHPC_00371	4.77e-98	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
MEDFPHPC_00372	8.69e-96	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
MEDFPHPC_00373	5.75e-98	ywnA	-	-	K	-	-	-	Transcriptional regulator
MEDFPHPC_00374	3.18e-206	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
MEDFPHPC_00375	6.02e-137	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MEDFPHPC_00376	2.21e-179	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00377	3.62e-128	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MEDFPHPC_00378	2.67e-155	-	-	-	V	-	-	-	site-specific DNA-methyltransferase (adenine-specific) activity
MEDFPHPC_00380	2.15e-144	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
MEDFPHPC_00381	1.37e-248	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
MEDFPHPC_00382	1.45e-278	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
MEDFPHPC_00383	6.6e-228	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MEDFPHPC_00384	8.4e-259	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
MEDFPHPC_00385	4.61e-120	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MEDFPHPC_00386	4.02e-300	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
MEDFPHPC_00387	1.83e-193	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
MEDFPHPC_00388	3.07e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
MEDFPHPC_00389	1.62e-213	yvgN	-	-	C	-	-	-	Aldo keto reductase
MEDFPHPC_00390	1.81e-200	-	-	-	S	-	-	-	DUF218 domain
MEDFPHPC_00391	7.5e-122	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
MEDFPHPC_00392	8.29e-206	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MEDFPHPC_00393	7.39e-157	-	-	-	S	-	-	-	Phage minor capsid protein 2
MEDFPHPC_00396	3.31e-30	-	-	-	E	-	-	-	Aminotransferase
MEDFPHPC_00397	4.81e-232	-	-	-	E	-	-	-	Aminotransferase
MEDFPHPC_00398	1.64e-188	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MEDFPHPC_00399	6.21e-13	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
MEDFPHPC_00400	5.86e-311	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
MEDFPHPC_00401	2.75e-118	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
MEDFPHPC_00402	1.74e-41	-	-	-	S	-	-	-	Fic/DOC family
MEDFPHPC_00403	1.71e-107	-	-	-	S	-	-	-	Fic/DOC family
MEDFPHPC_00404	1.58e-104	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MEDFPHPC_00405	7.35e-123	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
MEDFPHPC_00406	1.74e-252	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MEDFPHPC_00407	0.0	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
MEDFPHPC_00408	2.91e-153	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
MEDFPHPC_00409	2.34e-42	odh	1.5.1.28	-	C	ko:K04940	-	ko00000,ko01000	NAD NADP octopine nopaline dehydrogenase
MEDFPHPC_00410	5.72e-54	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MEDFPHPC_00411	7.03e-31	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MEDFPHPC_00412	1.92e-11	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MEDFPHPC_00413	2.3e-57	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MEDFPHPC_00414	5.63e-60	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MEDFPHPC_00415	4.89e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MEDFPHPC_00416	4.59e-307	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
MEDFPHPC_00417	3.21e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_00418	1.55e-98	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MEDFPHPC_00419	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MEDFPHPC_00421	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
MEDFPHPC_00422	2.17e-306	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
MEDFPHPC_00423	1.69e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
MEDFPHPC_00424	1.84e-104	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
MEDFPHPC_00425	1.21e-120	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
MEDFPHPC_00426	4.65e-100	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
MEDFPHPC_00427	2.26e-91	-	-	-	S	-	-	-	Belongs to the HesB IscA family
MEDFPHPC_00428	4.6e-220	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
MEDFPHPC_00429	4.2e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
MEDFPHPC_00430	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEDFPHPC_00431	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MEDFPHPC_00432	7.47e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MEDFPHPC_00433	7.34e-217	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
MEDFPHPC_00434	3.55e-195	-	-	-	D	-	-	-	DNA integration
MEDFPHPC_00435	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MEDFPHPC_00436	4.22e-211	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
MEDFPHPC_00437	1.01e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEDFPHPC_00438	9.88e-205	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MEDFPHPC_00439	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
MEDFPHPC_00440	5.75e-135	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
MEDFPHPC_00441	1e-216	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
MEDFPHPC_00442	1.99e-145	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
MEDFPHPC_00443	1.69e-277	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
MEDFPHPC_00444	6.38e-196	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
MEDFPHPC_00445	1.34e-139	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
MEDFPHPC_00446	4.4e-122	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MEDFPHPC_00447	1.03e-241	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MEDFPHPC_00448	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00449	2.95e-282	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MEDFPHPC_00450	1.81e-202	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
MEDFPHPC_00451	2.41e-298	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
MEDFPHPC_00452	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MEDFPHPC_00453	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
MEDFPHPC_00454	1.33e-274	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
MEDFPHPC_00455	3.8e-152	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
MEDFPHPC_00456	2.27e-67	-	-	-	M	-	-	-	Lysin motif
MEDFPHPC_00457	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
MEDFPHPC_00458	1.56e-253	-	-	-	S	-	-	-	Helix-turn-helix domain
MEDFPHPC_00459	2.03e-112	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MEDFPHPC_00460	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
MEDFPHPC_00461	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MEDFPHPC_00462	1.14e-180	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MEDFPHPC_00463	2.23e-89	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MEDFPHPC_00464	1.24e-183	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
MEDFPHPC_00465	6.26e-215	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
MEDFPHPC_00466	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
MEDFPHPC_00467	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
MEDFPHPC_00469	2.31e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
MEDFPHPC_00470	1.64e-199	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MEDFPHPC_00471	3.81e-160	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
MEDFPHPC_00472	6.86e-154	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
MEDFPHPC_00473	9.69e-293	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
MEDFPHPC_00474	3.01e-252	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MEDFPHPC_00475	2.21e-274	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MEDFPHPC_00476	1.49e-179	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MEDFPHPC_00477	5.18e-222	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MEDFPHPC_00478	4.48e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MEDFPHPC_00479	2.59e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MEDFPHPC_00480	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MEDFPHPC_00481	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
MEDFPHPC_00482	1.13e-228	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MEDFPHPC_00483	7.03e-216	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEDFPHPC_00484	2.41e-42	-	-	-	EGP	-	-	-	Major Facilitator
MEDFPHPC_00485	5.81e-58	-	-	-	EGP	-	-	-	Major Facilitator
MEDFPHPC_00486	2.6e-61	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MEDFPHPC_00487	9.2e-58	-	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
MEDFPHPC_00488	2.23e-260	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MEDFPHPC_00489	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MEDFPHPC_00490	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
MEDFPHPC_00491	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
MEDFPHPC_00492	1.25e-198	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
MEDFPHPC_00493	8.91e-218	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MEDFPHPC_00494	1.48e-85	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
MEDFPHPC_00495	3.97e-102	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MEDFPHPC_00496	3.53e-228	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
MEDFPHPC_00497	7.45e-85	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
MEDFPHPC_00498	1.56e-30	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
MEDFPHPC_00499	5.26e-164	-	-	-	F	-	-	-	glutamine amidotransferase
MEDFPHPC_00500	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MEDFPHPC_00501	2.3e-313	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
MEDFPHPC_00502	3.49e-247	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
MEDFPHPC_00503	8.38e-188	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
MEDFPHPC_00504	2.09e-212	-	-	-	G	-	-	-	Phosphotransferase enzyme family
MEDFPHPC_00505	1.3e-214	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
MEDFPHPC_00506	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
MEDFPHPC_00508	1.85e-201	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MEDFPHPC_00509	9.61e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
MEDFPHPC_00510	1.06e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MEDFPHPC_00511	1.19e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00512	3.56e-135	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
MEDFPHPC_00513	2.67e-144	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
MEDFPHPC_00515	9.37e-51	-	2.7.1.200	-	G	ko:K02774	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MEDFPHPC_00516	1.84e-275	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MEDFPHPC_00517	1.66e-59	-	2.7.1.200	-	GT	ko:K02773	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEDFPHPC_00518	1.61e-175	-	-	-	K	ko:K02538	-	ko00000,ko03000	PRD domain
MEDFPHPC_00519	1.52e-60	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
MEDFPHPC_00521	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00522	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00523	1.92e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00524	7.14e-192	-	-	-	ET	ko:K16957	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEDFPHPC_00525	5.62e-140	-	-	-	U	ko:K16959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
MEDFPHPC_00526	7e-92	-	-	-	P	ko:K16958	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEDFPHPC_00527	2.48e-172	tcyC2	-	-	E	ko:K10010,ko:K16960	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MEDFPHPC_00528	7.47e-235	-	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen decarboxylase (URO-D)
MEDFPHPC_00529	4.33e-260	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
MEDFPHPC_00530	9.64e-271	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
MEDFPHPC_00531	4.12e-108	-	-	-	K	-	-	-	Transcriptional regulator
MEDFPHPC_00532	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MEDFPHPC_00533	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MEDFPHPC_00534	4.23e-76	-	-	-	-	-	-	-	-
MEDFPHPC_00535	2.38e-171	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MEDFPHPC_00536	6.12e-230	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
MEDFPHPC_00537	2.79e-71	-	-	-	-	-	-	-	-
MEDFPHPC_00539	3.92e-220	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
MEDFPHPC_00540	2.18e-110	-	-	-	S	-	-	-	integral membrane protein
MEDFPHPC_00541	3.68e-86	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEDFPHPC_00542	9.26e-289	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00543	6.7e-43	-	-	-	S	-	-	-	CRISPR-associated protein (Cas_Csn2)
MEDFPHPC_00544	1.69e-46	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEDFPHPC_00545	1.19e-91	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEDFPHPC_00546	5.04e-10	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MEDFPHPC_00547	0.0	cas9	-	-	L	ko:K09952	-	ko00000,ko01000,ko02048	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MEDFPHPC_00548	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEDFPHPC_00549	1.28e-181	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MEDFPHPC_00550	1.1e-184	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MEDFPHPC_00551	6.88e-144	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MEDFPHPC_00552	1.08e-188	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
MEDFPHPC_00553	4.18e-89	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
MEDFPHPC_00554	7.87e-45	-	-	-	V	ko:K07052	-	ko00000	CAAX protease self-immunity
MEDFPHPC_00556	3.9e-90	-	-	-	K	-	-	-	LysR substrate binding domain
MEDFPHPC_00557	3.86e-206	-	1.1.1.90	-	C	ko:K00055	ko00350,ko00360,ko00622,ko00623,ko01100,ko01120,ko01220,map00350,map00360,map00622,map00623,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Zn-dependent alcohol dehydrogenases, class III
MEDFPHPC_00558	1.07e-125	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEDFPHPC_00559	1.2e-201	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MEDFPHPC_00560	5.05e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MEDFPHPC_00561	3.64e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
MEDFPHPC_00562	7.4e-131	cadD	-	-	P	-	-	-	Cadmium resistance transporter
MEDFPHPC_00563	7.66e-151	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MEDFPHPC_00564	1.19e-81	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MEDFPHPC_00565	2.61e-280	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MEDFPHPC_00568	2.66e-36	-	-	-	C	-	-	-	Flavodoxin
MEDFPHPC_00569	5e-252	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MEDFPHPC_00570	2.41e-134	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
MEDFPHPC_00571	7.27e-286	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MEDFPHPC_00572	1.28e-102	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MEDFPHPC_00573	9.68e-154	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEDFPHPC_00574	6.83e-37	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_00575	3.21e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_00576	1.39e-40	-	-	-	S	-	-	-	Transglycosylase associated protein
MEDFPHPC_00577	8.47e-106	-	-	-	S	-	-	-	cog cog1302
MEDFPHPC_00578	5.24e-33	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
MEDFPHPC_00579	6.51e-122	-	-	-	-	-	-	-	-
MEDFPHPC_00580	1.71e-284	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00581	3.9e-167	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00582	9.61e-305	-	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEDFPHPC_00583	2.1e-246	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
MEDFPHPC_00584	1.4e-27	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_00585	1.86e-24	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
MEDFPHPC_00586	5.29e-111	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MEDFPHPC_00587	4.83e-36	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00588	2.32e-279	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_00589	4.67e-254	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MEDFPHPC_00590	1.93e-133	-	-	-	C	-	-	-	aldo keto reductase
MEDFPHPC_00591	1.28e-136	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
MEDFPHPC_00593	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MEDFPHPC_00594	6.35e-255	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MEDFPHPC_00595	5.11e-67	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
MEDFPHPC_00596	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MEDFPHPC_00597	2.27e-122	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MEDFPHPC_00598	8.87e-77	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MEDFPHPC_00600	3.15e-260	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MEDFPHPC_00601	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
MEDFPHPC_00602	1.97e-86	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MEDFPHPC_00603	3.31e-242	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MEDFPHPC_00604	1.35e-80	-	-	-	-	-	-	-	-
MEDFPHPC_00605	5.64e-156	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_00606	5.39e-150	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00607	0.0	-	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MEDFPHPC_00608	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, catalytic domain protein
MEDFPHPC_00609	1.66e-222	-	-	-	K	ko:K02529,ko:K03604	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEDFPHPC_00610	4.74e-176	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Belongs to the DNA polymerase type-Y family
MEDFPHPC_00611	9.06e-69	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_00612	7.42e-75	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_00613	1.49e-165	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEDFPHPC_00615	7.93e-290	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00616	2.1e-269	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00617	3.72e-50	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MEDFPHPC_00618	1.93e-110	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MEDFPHPC_00619	2.23e-313	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MEDFPHPC_00620	8.39e-233	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
MEDFPHPC_00621	3.09e-212	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MEDFPHPC_00622	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MEDFPHPC_00623	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MEDFPHPC_00624	3.19e-66	ylxQ	-	-	J	-	-	-	ribosomal protein
MEDFPHPC_00625	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
MEDFPHPC_00626	7.81e-282	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
MEDFPHPC_00627	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
MEDFPHPC_00628	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
MEDFPHPC_00629	4.36e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
MEDFPHPC_00630	1.49e-252	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MEDFPHPC_00631	4.76e-262	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MEDFPHPC_00632	5.88e-176	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
MEDFPHPC_00633	3.26e-275	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
MEDFPHPC_00634	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEDFPHPC_00635	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MEDFPHPC_00636	4.84e-295	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
MEDFPHPC_00637	9.58e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
MEDFPHPC_00638	1.01e-180	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MEDFPHPC_00639	5.35e-121	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MEDFPHPC_00640	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
MEDFPHPC_00641	5.63e-196	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MEDFPHPC_00642	1.28e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
MEDFPHPC_00643	8.95e-61	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
MEDFPHPC_00644	1.62e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
MEDFPHPC_00645	2.94e-148	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
MEDFPHPC_00646	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
MEDFPHPC_00647	3.28e-48	ynzC	-	-	S	-	-	-	UPF0291 protein
MEDFPHPC_00648	5.09e-148	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MEDFPHPC_00649	4.1e-272	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
MEDFPHPC_00650	9e-127	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_00651	1.78e-110	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_00652	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_00653	3.02e-35	yitW	-	-	S	-	-	-	DNA methyltransferase
MEDFPHPC_00654	2.18e-141	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MEDFPHPC_00655	9.39e-82	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
MEDFPHPC_00658	2.9e-08	-	-	-	IQ	-	-	-	oxidoreductase activity
MEDFPHPC_00659	8.35e-107	-	-	-	S	-	-	-	Carboxymuconolactone decarboxylase family
MEDFPHPC_00662	2.26e-23	-	-	-	-	-	-	-	-
MEDFPHPC_00663	1.12e-07	-	2.1.1.72, 3.1.21.3	-	V	ko:K01153,ko:K01154,ko:K03427	-	ko00000,ko01000,ko02048	site-specific DNA-methyltransferase (adenine-specific) activity
MEDFPHPC_00664	2.72e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MEDFPHPC_00665	2.77e-185	cylB	-	-	V	ko:K11051	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 type transporter
MEDFPHPC_00666	4.66e-197	cylA	-	-	V	ko:K11050	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MEDFPHPC_00667	4.04e-129	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
MEDFPHPC_00668	1.7e-147	-	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
MEDFPHPC_00669	0.0	-	-	-	M	ko:K01992	-	ko00000,ko00002,ko02000	Exporter of polyketide antibiotics
MEDFPHPC_00670	5.69e-207	ybhF_1	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
MEDFPHPC_00671	6.32e-157	-	-	-	-	-	-	-	-
MEDFPHPC_00672	2e-81	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEDFPHPC_00673	1.19e-150	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEDFPHPC_00674	8.33e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_00675	2.1e-216	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_00676	2.19e-271	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00677	4.57e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_00678	1.54e-57	-	-	-	S	-	-	-	AAA domain
MEDFPHPC_00679	0.0	-	-	-	S	-	-	-	Protein of unknown function DUF262
MEDFPHPC_00680	6.45e-27	-	-	-	-	-	-	-	-
MEDFPHPC_00681	7.93e-290	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00682	1.38e-67	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00683	7.17e-184	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00684	1.14e-95	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_00685	2.54e-96	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_00687	1.38e-120	-	-	-	-	-	-	-	-
MEDFPHPC_00688	8.2e-102	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
MEDFPHPC_00689	3.68e-231	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEDFPHPC_00691	5.21e-146	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
MEDFPHPC_00694	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
MEDFPHPC_00695	2.29e-236	-	-	-	EGP	-	-	-	Major Facilitator
MEDFPHPC_00697	5e-253	gldA	1.1.1.6	-	C	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	ko00000,ko00001,ko01000	dehydrogenase
MEDFPHPC_00698	4.78e-60	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00699	4.29e-167	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00700	6.02e-68	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
MEDFPHPC_00701	3.03e-74	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
MEDFPHPC_00702	1.97e-57	-	-	-	S	-	-	-	Protein conserved in bacteria
MEDFPHPC_00703	5.94e-87	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MEDFPHPC_00704	2.14e-17	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
MEDFPHPC_00705	1.71e-48	-	-	-	K	-	-	-	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MEDFPHPC_00706	2.7e-09	adhR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MEDFPHPC_00707	5.9e-191	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
MEDFPHPC_00708	3.19e-238	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_00709	1.71e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
MEDFPHPC_00710	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MEDFPHPC_00711	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
MEDFPHPC_00712	1.24e-197	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
MEDFPHPC_00713	8.64e-225	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MEDFPHPC_00714	5.73e-316	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MEDFPHPC_00715	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MEDFPHPC_00716	4.63e-173	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00718	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
MEDFPHPC_00719	1.26e-138	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
MEDFPHPC_00720	5.9e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MEDFPHPC_00721	9.07e-297	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MEDFPHPC_00722	4.94e-288	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MEDFPHPC_00723	5.46e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
MEDFPHPC_00724	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEDFPHPC_00725	3.31e-81	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MEDFPHPC_00726	1.42e-194	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MEDFPHPC_00727	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MEDFPHPC_00728	3.39e-46	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
MEDFPHPC_00729	1.63e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
MEDFPHPC_00730	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
MEDFPHPC_00731	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
MEDFPHPC_00732	3.46e-126	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
MEDFPHPC_00733	5.62e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
MEDFPHPC_00734	5.91e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MEDFPHPC_00735	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
MEDFPHPC_00736	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
MEDFPHPC_00737	3.64e-271	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
MEDFPHPC_00738	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
MEDFPHPC_00739	3.26e-176	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
MEDFPHPC_00740	4.44e-65	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
MEDFPHPC_00741	8.59e-133	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MEDFPHPC_00742	6.12e-98	-	-	-	-	-	-	-	-
MEDFPHPC_00743	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
MEDFPHPC_00744	1.15e-236	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
MEDFPHPC_00745	2.39e-98	-	-	-	P	-	-	-	ArsC family
MEDFPHPC_00746	1.55e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEDFPHPC_00747	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MEDFPHPC_00748	9.37e-159	-	-	-	S	-	-	-	repeat protein
MEDFPHPC_00749	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
MEDFPHPC_00750	1.08e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MEDFPHPC_00751	0.0	-	-	-	S	-	-	-	amidohydrolase
MEDFPHPC_00752	3.43e-283	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MEDFPHPC_00753	4.55e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
MEDFPHPC_00754	3.96e-163	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MEDFPHPC_00755	2.68e-08	-	-	-	-	-	-	-	-
MEDFPHPC_00756	1.28e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
MEDFPHPC_00757	9.99e-44	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MEDFPHPC_00758	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MEDFPHPC_00760	3.58e-142	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
MEDFPHPC_00761	2.39e-184	ylmH	-	-	S	-	-	-	S4 domain protein
MEDFPHPC_00762	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
MEDFPHPC_00763	8.67e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MEDFPHPC_00764	3.01e-292	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MEDFPHPC_00765	7.72e-297	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MEDFPHPC_00766	3.51e-189	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MEDFPHPC_00767	2.31e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MEDFPHPC_00768	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MEDFPHPC_00769	5.43e-228	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MEDFPHPC_00770	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MEDFPHPC_00771	5.28e-31	ftsL	-	-	D	-	-	-	Cell division protein FtsL
MEDFPHPC_00772	3.63e-219	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MEDFPHPC_00773	1.81e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
MEDFPHPC_00774	9.82e-76	-	-	-	-	-	-	-	-
MEDFPHPC_00775	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
MEDFPHPC_00776	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
MEDFPHPC_00777	2.01e-123	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MEDFPHPC_00778	6.94e-202	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
MEDFPHPC_00779	2.11e-248	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MEDFPHPC_00780	1.55e-220	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MEDFPHPC_00781	2.61e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MEDFPHPC_00782	1.75e-157	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
MEDFPHPC_00783	1.03e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
MEDFPHPC_00784	9.03e-258	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
MEDFPHPC_00785	2.07e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MEDFPHPC_00786	4.57e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MEDFPHPC_00807	8.34e-101	-	-	-	-	-	-	-	-
MEDFPHPC_00808	1.32e-138	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
MEDFPHPC_00809	1.35e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
MEDFPHPC_00810	1.01e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MEDFPHPC_00811	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
MEDFPHPC_00812	2.73e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MEDFPHPC_00813	1.3e-284	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MEDFPHPC_00814	4.86e-200	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
MEDFPHPC_00819	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
MEDFPHPC_00820	1.68e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
MEDFPHPC_00821	7.71e-228	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
MEDFPHPC_00822	0.0	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
MEDFPHPC_00823	2.23e-111	-	-	-	M	-	-	-	PFAM NLP P60 protein
MEDFPHPC_00824	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
MEDFPHPC_00825	2.71e-179	-	-	-	-	-	-	-	-
MEDFPHPC_00826	1.4e-236	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
MEDFPHPC_00827	2.55e-271	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
MEDFPHPC_00828	4.62e-92	-	-	-	-	-	-	-	-
MEDFPHPC_00829	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MEDFPHPC_00830	6.13e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
MEDFPHPC_00831	1.18e-191	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MEDFPHPC_00832	2.16e-119	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
MEDFPHPC_00833	4.21e-137	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MEDFPHPC_00834	7.44e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
MEDFPHPC_00835	7.99e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
MEDFPHPC_00836	7.31e-259	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_00837	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_00838	2.08e-283	-	-	-	P	-	-	-	Chloride transporter, ClC family
MEDFPHPC_00839	1.66e-71	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MEDFPHPC_00840	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MEDFPHPC_00841	6.13e-117	cvpA	-	-	S	-	-	-	Colicin V production protein
MEDFPHPC_00842	1.46e-207	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MEDFPHPC_00843	3.99e-55	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
MEDFPHPC_00844	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MEDFPHPC_00845	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
MEDFPHPC_00846	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MEDFPHPC_00847	4.66e-298	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MEDFPHPC_00848	1.81e-228	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
MEDFPHPC_00849	3.17e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MEDFPHPC_00850	2.85e-222	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
MEDFPHPC_00851	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MEDFPHPC_00852	8.79e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MEDFPHPC_00853	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MEDFPHPC_00854	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MEDFPHPC_00855	1.32e-297	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
MEDFPHPC_00856	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MEDFPHPC_00857	2.68e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
MEDFPHPC_00858	2.34e-128	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MEDFPHPC_00859	1.64e-151	-	-	-	S	-	-	-	Helix-turn-helix domain
MEDFPHPC_00860	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
MEDFPHPC_00861	9.05e-296	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
MEDFPHPC_00862	3.88e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
MEDFPHPC_00863	2.81e-148	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00864	1.09e-141	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MEDFPHPC_00865	3.68e-119	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
MEDFPHPC_00866	1.95e-187	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
MEDFPHPC_00867	1.34e-232	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
MEDFPHPC_00868	1.03e-147	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
MEDFPHPC_00869	6.9e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MEDFPHPC_00870	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MEDFPHPC_00871	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MEDFPHPC_00874	3.27e-19	-	-	-	S	-	-	-	zinc-ribbon domain
MEDFPHPC_00875	1.16e-50	-	-	-	-	-	-	-	-
MEDFPHPC_00876	6.29e-45	-	-	-	M	-	-	-	LysM domain
MEDFPHPC_00877	1.35e-261	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
MEDFPHPC_00878	1.32e-276	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
MEDFPHPC_00879	3.93e-290	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MEDFPHPC_00880	4.79e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
MEDFPHPC_00881	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MEDFPHPC_00882	5.96e-139	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MEDFPHPC_00885	2.8e-20	-	-	-	S	-	-	-	YjcQ protein
MEDFPHPC_00886	1.74e-189	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MEDFPHPC_00887	2.3e-173	-	-	-	S	-	-	-	Membrane
MEDFPHPC_00888	5.1e-97	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
MEDFPHPC_00889	1.9e-109	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
MEDFPHPC_00890	2.15e-299	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
MEDFPHPC_00892	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
MEDFPHPC_00893	5.45e-192	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEDFPHPC_00894	7.02e-268	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00895	2.78e-273	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
MEDFPHPC_00896	2.29e-229	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
MEDFPHPC_00898	2.82e-280	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
MEDFPHPC_00899	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
MEDFPHPC_00900	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
MEDFPHPC_00901	5.41e-275	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
MEDFPHPC_00902	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
MEDFPHPC_00903	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
MEDFPHPC_00904	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MEDFPHPC_00905	7.25e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MEDFPHPC_00906	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MEDFPHPC_00907	1.23e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEDFPHPC_00908	1.31e-78	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MEDFPHPC_00909	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MEDFPHPC_00910	5.66e-168	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
MEDFPHPC_00911	1.1e-295	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
MEDFPHPC_00912	7.81e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
MEDFPHPC_00913	4.71e-251	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
MEDFPHPC_00914	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MEDFPHPC_00915	1.49e-292	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MEDFPHPC_00916	8.89e-246	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MEDFPHPC_00917	1.07e-200	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MEDFPHPC_00918	4.39e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MEDFPHPC_00919	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
MEDFPHPC_00920	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
MEDFPHPC_00921	7.49e-181	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
MEDFPHPC_00922	2.31e-63	-	-	-	-	-	-	-	-
MEDFPHPC_00923	1.02e-192	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDFPHPC_00924	7.23e-76	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDFPHPC_00925	1.91e-45	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDFPHPC_00926	8.86e-244	ampC	-	-	V	-	-	-	Beta-lactamase
MEDFPHPC_00927	0.0	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
MEDFPHPC_00928	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_00929	8.08e-100	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
MEDFPHPC_00930	4.15e-14	-	-	-	-	-	-	-	-
MEDFPHPC_00932	1.55e-74	-	-	-	-	-	-	-	-
MEDFPHPC_00934	1.06e-167	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
MEDFPHPC_00935	4.49e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEDFPHPC_00936	7.54e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
MEDFPHPC_00937	3.36e-154	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
MEDFPHPC_00938	5.95e-99	-	-	-	K	-	-	-	GNAT family
MEDFPHPC_00940	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MEDFPHPC_00941	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
MEDFPHPC_00942	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
MEDFPHPC_00943	4.26e-54	-	-	-	K	-	-	-	AraC-like ligand binding domain
MEDFPHPC_00944	2.81e-60	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_00945	1.71e-35	bglB	3.2.1.21	GH3	G	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Glycosyl hydrolase family 3 C-terminal domain
MEDFPHPC_00946	0.0	-	-	-	G	-	-	-	Right handed beta helix region
MEDFPHPC_00947	8.52e-317	-	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
MEDFPHPC_00948	4.01e-128	rhaS2	-	-	K	-	-	-	Transcriptional regulator, AraC family
MEDFPHPC_00949	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Xylulose kinase
MEDFPHPC_00950	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
MEDFPHPC_00951	0.0	xylT	-	-	EGP	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEDFPHPC_00952	2.12e-274	xylR	-	-	GK	-	-	-	ROK family
MEDFPHPC_00953	2.91e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
MEDFPHPC_00954	0.0	yclK	-	-	T	-	-	-	Histidine kinase
MEDFPHPC_00955	1.14e-169	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
MEDFPHPC_00957	7.33e-76	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
MEDFPHPC_00958	3.23e-218	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
MEDFPHPC_00959	1.95e-163	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
MEDFPHPC_00960	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
MEDFPHPC_00961	7.04e-126	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MEDFPHPC_00962	2.9e-63	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
MEDFPHPC_00963	6.93e-114	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MEDFPHPC_00964	1.49e-189	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
MEDFPHPC_00965	1.56e-163	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
MEDFPHPC_00966	1.93e-212	-	-	-	K	-	-	-	LysR substrate binding domain
MEDFPHPC_00967	2.83e-221	-	-	-	S	-	-	-	Conserved hypothetical protein 698
MEDFPHPC_00968	6.82e-106	lytE	-	-	M	-	-	-	Lysin motif
MEDFPHPC_00969	1.75e-192	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
MEDFPHPC_00970	1.1e-260	oatA	-	-	I	-	-	-	Acyltransferase
MEDFPHPC_00971	2.55e-68	-	-	-	-	-	-	-	-
MEDFPHPC_00972	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MEDFPHPC_00973	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MEDFPHPC_00974	8e-150	ybbR	-	-	S	-	-	-	YbbR-like protein
MEDFPHPC_00975	1.09e-190	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MEDFPHPC_00976	1.35e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
MEDFPHPC_00977	4.67e-132	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MEDFPHPC_00978	5.51e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
MEDFPHPC_00979	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
MEDFPHPC_00980	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
MEDFPHPC_00981	4.35e-173	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MEDFPHPC_00982	2.02e-140	-	-	-	-	-	-	-	-
MEDFPHPC_00983	3.83e-109	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MEDFPHPC_00984	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MEDFPHPC_00985	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
MEDFPHPC_00986	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
MEDFPHPC_00987	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
MEDFPHPC_00988	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MEDFPHPC_00989	8.38e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MEDFPHPC_00990	8.52e-287	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
MEDFPHPC_00991	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MEDFPHPC_00992	9.05e-22	-	-	-	-	-	-	-	-
MEDFPHPC_00993	7.49e-18	-	-	-	L	-	-	-	Plasmid pRiA4b ORF-3-like protein
MEDFPHPC_00995	1.73e-268	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_00996	5.72e-196	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_00997	2.46e-102	tspO	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	TspO/MBR family
MEDFPHPC_00998	1.53e-19	-	-	-	-	-	-	-	-
MEDFPHPC_00999	5.17e-271	-	-	-	L	ko:K07485	-	ko00000	Transposase
MEDFPHPC_01003	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MEDFPHPC_01004	3.3e-152	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MEDFPHPC_01005	6.71e-214	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
MEDFPHPC_01006	3.31e-239	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
MEDFPHPC_01007	1.45e-201	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
MEDFPHPC_01008	1.56e-255	-	-	-	-	-	-	-	-
MEDFPHPC_01009	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MEDFPHPC_01010	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MEDFPHPC_01012	1.24e-145	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
MEDFPHPC_01013	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MEDFPHPC_01014	1.63e-173	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MEDFPHPC_01015	2.76e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MEDFPHPC_01016	4.82e-254	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
MEDFPHPC_01017	1.16e-212	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
MEDFPHPC_01018	4.5e-196	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
MEDFPHPC_01019	4.74e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MEDFPHPC_01020	1.11e-101	yphH	-	-	S	-	-	-	Cupin domain
MEDFPHPC_01021	3.44e-238	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MEDFPHPC_01022	1.58e-282	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MEDFPHPC_01023	4.33e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
MEDFPHPC_01024	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
MEDFPHPC_01025	5.26e-235	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
MEDFPHPC_01026	1.31e-209	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MEDFPHPC_01027	6.84e-227	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MEDFPHPC_01028	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
MEDFPHPC_01029	2.7e-68	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
MEDFPHPC_01030	2.5e-258	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MEDFPHPC_01031	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MEDFPHPC_01032	3.26e-122	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MEDFPHPC_01033	4.17e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
MEDFPHPC_01034	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
MEDFPHPC_01035	9.05e-144	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
MEDFPHPC_01036	4.12e-50	-	-	-	-	-	-	-	-
MEDFPHPC_01037	0.0	ydaO	-	-	E	-	-	-	amino acid
MEDFPHPC_01038	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MEDFPHPC_01039	8.11e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MEDFPHPC_01040	3.83e-147	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MEDFPHPC_01041	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
MEDFPHPC_01042	4.74e-221	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MEDFPHPC_01043	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
MEDFPHPC_01044	3.12e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
MEDFPHPC_01045	1.1e-180	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
MEDFPHPC_01046	3.74e-205	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MEDFPHPC_01047	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MEDFPHPC_01048	6.55e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEDFPHPC_01049	3.33e-92	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEDFPHPC_01050	1.32e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MEDFPHPC_01051	5.38e-165	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
MEDFPHPC_01052	1.86e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
MEDFPHPC_01053	4.18e-46	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MEDFPHPC_01054	4.21e-216	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MEDFPHPC_01055	1.32e-97	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
MEDFPHPC_01056	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MEDFPHPC_01058	2.87e-247	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MEDFPHPC_01059	7.57e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
MEDFPHPC_01060	1.13e-166	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
MEDFPHPC_01061	2.56e-271	arcT	-	-	E	-	-	-	Aminotransferase
MEDFPHPC_01062	8.27e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MEDFPHPC_01063	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
MEDFPHPC_01064	1.99e-304	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
MEDFPHPC_01065	4.08e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
MEDFPHPC_01066	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MEDFPHPC_01067	2.96e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MEDFPHPC_01068	1.02e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
MEDFPHPC_01069	6.74e-244	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
MEDFPHPC_01070	2.27e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MEDFPHPC_01071	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MEDFPHPC_01072	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MEDFPHPC_01073	6.67e-188	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
MEDFPHPC_01074	2.83e-202	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MEDFPHPC_01075	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
MEDFPHPC_01076	1.12e-245	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
MEDFPHPC_01077	2.25e-70	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
MEDFPHPC_01078	6.36e-145	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MEDFPHPC_01079	1.39e-26	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
MEDFPHPC_01080	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MEDFPHPC_01081	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MEDFPHPC_01082	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MEDFPHPC_01084	2.29e-107	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MEDFPHPC_01085	2.21e-46	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
MEDFPHPC_01086	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEDFPHPC_01087	1.48e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEDFPHPC_01088	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MEDFPHPC_01090	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
MEDFPHPC_01091	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MEDFPHPC_01092	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MEDFPHPC_01093	1.4e-235	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
MEDFPHPC_01094	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
MEDFPHPC_01095	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MEDFPHPC_01096	6.43e-106	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MEDFPHPC_01097	1.82e-311	steT	-	-	E	ko:K03294	-	ko00000	amino acid
MEDFPHPC_01098	2.53e-242	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MEDFPHPC_01099	2.78e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MEDFPHPC_01100	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MEDFPHPC_01101	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
MEDFPHPC_01102	1.01e-31	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MEDFPHPC_01103	7.09e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MEDFPHPC_01104	4.4e-132	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
MEDFPHPC_01105	1.01e-173	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEDFPHPC_01106	1.25e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MEDFPHPC_01107	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MEDFPHPC_01108	9.63e-130	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
MEDFPHPC_01109	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MEDFPHPC_01110	1.58e-263	yacL	-	-	S	-	-	-	domain protein
MEDFPHPC_01111	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MEDFPHPC_01112	3.27e-123	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
MEDFPHPC_01113	7.63e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
MEDFPHPC_01114	7.96e-259	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01115	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01116	1.4e-148	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEDFPHPC_01117	6.69e-142	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MEDFPHPC_01118	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
MEDFPHPC_01119	2.99e-219	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01120	2.97e-211	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MEDFPHPC_01121	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEDFPHPC_01122	1.19e-210	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
MEDFPHPC_01123	2.16e-239	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
MEDFPHPC_01124	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
MEDFPHPC_01126	5.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
MEDFPHPC_01127	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
MEDFPHPC_01128	1.1e-194	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MEDFPHPC_01129	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEDFPHPC_01130	5.03e-165	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
MEDFPHPC_01131	3.69e-169	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
MEDFPHPC_01132	1.34e-148	-	-	-	-	-	-	-	-
MEDFPHPC_01135	2.64e-209	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
MEDFPHPC_01136	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
MEDFPHPC_01137	9.97e-214	-	-	-	D	-	-	-	nuclear chromosome segregation
MEDFPHPC_01138	2.8e-190	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_01140	5.5e-66	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_01141	2.22e-34	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_01144	8.34e-101	-	-	-	-	-	-	-	-
MEDFPHPC_01148	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
MEDFPHPC_01149	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MEDFPHPC_01150	4.73e-209	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MEDFPHPC_01151	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MEDFPHPC_01152	3.01e-125	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
MEDFPHPC_01153	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MEDFPHPC_01154	2.74e-112	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
MEDFPHPC_01155	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
MEDFPHPC_01156	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
MEDFPHPC_01157	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MEDFPHPC_01158	7.98e-132	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MEDFPHPC_01159	1.51e-146	-	-	-	S	-	-	-	(CBS) domain
MEDFPHPC_01160	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
MEDFPHPC_01161	6.25e-268	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MEDFPHPC_01162	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MEDFPHPC_01163	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MEDFPHPC_01164	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MEDFPHPC_01165	1.9e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
MEDFPHPC_01166	1.94e-118	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
MEDFPHPC_01167	4.28e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MEDFPHPC_01168	5.15e-259	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01169	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01170	6.28e-157	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
MEDFPHPC_01171	5.53e-42	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MEDFPHPC_01172	6.13e-10	mdtG	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MEDFPHPC_01173	1.25e-07	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
MEDFPHPC_01174	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
MEDFPHPC_01175	1.25e-301	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MEDFPHPC_01176	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MEDFPHPC_01177	9.7e-86	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MEDFPHPC_01178	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
MEDFPHPC_01179	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
MEDFPHPC_01180	6.51e-181	yidA	-	-	S	-	-	-	hydrolase
MEDFPHPC_01181	1.89e-73	-	-	-	-	-	-	-	-
MEDFPHPC_01182	8.23e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MEDFPHPC_01183	2.72e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MEDFPHPC_01184	6.12e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
MEDFPHPC_01185	8.05e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
MEDFPHPC_01186	1.29e-119	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
MEDFPHPC_01187	2.73e-210	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
MEDFPHPC_01188	7.82e-203	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MEDFPHPC_01189	1.2e-203	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MEDFPHPC_01190	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MEDFPHPC_01191	1.29e-186	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
MEDFPHPC_01192	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MEDFPHPC_01193	3.89e-206	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
MEDFPHPC_01194	5.57e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
MEDFPHPC_01195	9.4e-165	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
MEDFPHPC_01196	1.35e-239	-	-	-	-	-	-	-	-
MEDFPHPC_01197	4.16e-281	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
MEDFPHPC_01198	7.63e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
MEDFPHPC_01199	0.0	-	-	-	L	-	-	-	DNA helicase
MEDFPHPC_01200	8.65e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MEDFPHPC_01201	3.69e-196	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MEDFPHPC_01203	4.13e-179	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
MEDFPHPC_01205	2.12e-114	-	-	-	K	-	-	-	Transcriptional regulator
MEDFPHPC_01206	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
MEDFPHPC_01207	5.19e-251	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MEDFPHPC_01208	7.2e-69	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
MEDFPHPC_01209	1.34e-174	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MEDFPHPC_01210	2.52e-156	-	-	-	C	-	-	-	nitroreductase
MEDFPHPC_01211	1.18e-223	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
MEDFPHPC_01212	8.04e-163	cpkA	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Amino acid kinase family
MEDFPHPC_01213	4.16e-19	-	-	-	S	-	-	-	Protein of unknown function (DUF2877)
MEDFPHPC_01214	4.43e-274	-	-	-	C	-	-	-	Protein of unknown function (DUF1116)
MEDFPHPC_01215	5.71e-303	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
MEDFPHPC_01216	4.67e-258	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
MEDFPHPC_01217	2.8e-162	ylbA	3.5.3.26	-	S	ko:K14977	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	protein, possibly involved in glyoxylate utilization
MEDFPHPC_01218	2.5e-288	allC	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	Peptidase family M20/M25/M40
MEDFPHPC_01219	1.17e-283	-	3.5.2.3, 3.5.2.5	-	F	ko:K01465,ko:K01466	ko00230,ko00240,ko01100,ko01120,map00230,map00240,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MEDFPHPC_01220	7.68e-161	-	-	-	FH	ko:K03457	-	ko00000	Permease for cytosine/purines, uracil, thiamine, allantoin
MEDFPHPC_01221	4.19e-85	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MEDFPHPC_01222	1.39e-234	-	-	-	QT	ko:K09684	-	ko00000,ko03000	Purine catabolism regulatory protein-like family
MEDFPHPC_01223	5.86e-194	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
MEDFPHPC_01224	9.02e-229	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_01225	4.83e-100	-	-	-	-	-	-	-	-
MEDFPHPC_01226	1.16e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
MEDFPHPC_01227	3.09e-58	-	-	-	-	-	-	-	-
MEDFPHPC_01228	4.14e-08	-	-	-	M	-	-	-	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MEDFPHPC_01230	1.21e-257	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01231	7.48e-92	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01232	1.58e-301	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
MEDFPHPC_01233	2.12e-179	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01234	1.38e-188	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MEDFPHPC_01235	8.93e-193	isdE	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
MEDFPHPC_01236	5.34e-129	-	-	-	M	ko:K14193	ko05150,map05150	ko00000,ko00001	Iron Transport-associated domain
MEDFPHPC_01237	0.0	-	-	-	M	-	-	-	Iron Transport-associated domain
MEDFPHPC_01238	9.23e-45	-	-	-	M	-	-	-	Iron Transport-associated domain
MEDFPHPC_01239	4.25e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MEDFPHPC_01240	1.24e-298	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01241	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01242	2.02e-116	-	-	-	P	-	-	-	Cadmium resistance transporter
MEDFPHPC_01243	4.48e-35	-	-	-	C	-	-	-	Aldo/keto reductase family
MEDFPHPC_01245	0.000957	-	-	-	S	-	-	-	CsbD-like
MEDFPHPC_01246	8.56e-81	-	-	-	C	-	-	-	Aldo keto reductase
MEDFPHPC_01249	2.15e-71	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
MEDFPHPC_01250	9.52e-286	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01251	3.57e-59	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01252	4.36e-30	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
MEDFPHPC_01253	4.65e-149	pnb	-	-	C	-	-	-	nitroreductase
MEDFPHPC_01254	1.15e-06	-	-	-	K	ko:K01420	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
MEDFPHPC_01255	4.81e-57	yodA	-	-	S	-	-	-	Tautomerase enzyme
MEDFPHPC_01256	1.97e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MEDFPHPC_01257	7.74e-278	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01261	8.34e-101	-	-	-	-	-	-	-	-
MEDFPHPC_01262	6.87e-117	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
MEDFPHPC_01263	2.75e-197	-	-	-	EGP	-	-	-	Major Facilitator
MEDFPHPC_01264	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
MEDFPHPC_01265	3.67e-65	-	-	-	S	-	-	-	Cupredoxin-like domain
MEDFPHPC_01266	1.77e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
MEDFPHPC_01267	5.57e-224	-	-	-	-	-	-	-	-
MEDFPHPC_01268	1.35e-283	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MEDFPHPC_01269	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MEDFPHPC_01270	4.42e-260	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01271	4.94e-39	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01272	1.81e-307	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
MEDFPHPC_01273	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
MEDFPHPC_01274	5.36e-138	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MEDFPHPC_01275	1.61e-249	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
MEDFPHPC_01276	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MEDFPHPC_01277	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEDFPHPC_01278	9.43e-162	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEDFPHPC_01279	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MEDFPHPC_01280	1.51e-174	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
MEDFPHPC_01281	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
MEDFPHPC_01282	6.3e-218	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
MEDFPHPC_01283	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MEDFPHPC_01284	4.61e-273	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MEDFPHPC_01285	3.93e-104	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MEDFPHPC_01286	7.65e-261	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01287	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01288	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
MEDFPHPC_01289	2.72e-221	ydbI	-	-	K	-	-	-	AI-2E family transporter
MEDFPHPC_01290	2.42e-281	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01292	2.39e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
MEDFPHPC_01293	5.58e-79	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
MEDFPHPC_01294	4.31e-76	-	-	-	S	-	-	-	branched-chain amino acid
MEDFPHPC_01295	6.89e-177	-	-	-	E	-	-	-	AzlC protein
MEDFPHPC_01296	4.4e-265	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MEDFPHPC_01297	4.21e-265	hpk31	-	-	T	-	-	-	Histidine kinase
MEDFPHPC_01298	3.03e-158	vanR	-	-	K	-	-	-	response regulator
MEDFPHPC_01299	3.61e-09	-	-	-	S	-	-	-	Acyltransferase family
MEDFPHPC_01300	1.51e-199	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_01301	6.42e-80	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MEDFPHPC_01302	4.45e-130	-	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MEDFPHPC_01303	3.67e-21	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_01305	1.21e-63	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MEDFPHPC_01306	2.02e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01307	5.75e-52	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MEDFPHPC_01308	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
MEDFPHPC_01309	1.84e-39	-	-	-	M	-	-	-	Glycosyltransferase like family 2
MEDFPHPC_01311	5e-102	-	-	-	M	-	-	-	Glycosyltransferase sugar-binding region containing DXD motif
MEDFPHPC_01312	1.61e-59	-	-	-	S	-	-	-	Glycosyltransferase like family 2
MEDFPHPC_01313	2.34e-88	-	-	-	M	-	-	-	Glycosyl transferase family 2
MEDFPHPC_01314	4.78e-13	-	-	-	M	-	-	-	Glycosyl transferase family 2
MEDFPHPC_01315	2.09e-121	tuaA	-	-	M	-	-	-	Bacterial sugar transferase
MEDFPHPC_01316	5.79e-167	cps2D	5.1.3.2, 5.1.3.25	-	M	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	ko00000,ko00001,ko00002,ko01000	RmlD substrate binding domain
MEDFPHPC_01317	1.33e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
MEDFPHPC_01318	2.57e-148	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
MEDFPHPC_01319	1.12e-168	epsB	-	-	M	-	-	-	biosynthesis protein
MEDFPHPC_01320	1.64e-216	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MEDFPHPC_01321	8.13e-263	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEDFPHPC_01322	2.28e-173	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
MEDFPHPC_01323	2.13e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MEDFPHPC_01324	1.78e-42	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
MEDFPHPC_01325	7.2e-187	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MEDFPHPC_01326	2.71e-208	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
MEDFPHPC_01327	6.1e-172	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
MEDFPHPC_01328	3.82e-184	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
MEDFPHPC_01329	2.45e-269	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
MEDFPHPC_01330	3.18e-315	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MEDFPHPC_01331	1.1e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01332	1.48e-283	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
MEDFPHPC_01334	9.49e-238	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
MEDFPHPC_01335	5.92e-58	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01336	2.85e-287	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01338	4.3e-314	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MEDFPHPC_01339	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
MEDFPHPC_01340	8.66e-277	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MEDFPHPC_01341	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
MEDFPHPC_01342	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEDFPHPC_01343	7.53e-305	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
MEDFPHPC_01344	1.54e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MEDFPHPC_01345	2.28e-308	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MEDFPHPC_01346	4.39e-154	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
MEDFPHPC_01347	4.62e-249	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
MEDFPHPC_01348	1.14e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEDFPHPC_01349	2.48e-274	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
MEDFPHPC_01350	1.67e-138	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
MEDFPHPC_01351	2.73e-241	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MEDFPHPC_01352	1.29e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
MEDFPHPC_01353	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
MEDFPHPC_01354	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
MEDFPHPC_01355	1.33e-60	-	-	-	-	-	-	-	-
MEDFPHPC_01356	9.17e-15	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
MEDFPHPC_01357	6.19e-149	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MEDFPHPC_01358	5.85e-169	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MEDFPHPC_01359	8.04e-124	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MEDFPHPC_01360	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
MEDFPHPC_01361	8.33e-315	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MEDFPHPC_01362	2.81e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MEDFPHPC_01363	6.44e-122	-	-	-	K	-	-	-	transcriptional regulator
MEDFPHPC_01364	1.32e-165	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
MEDFPHPC_01365	3.79e-236	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MEDFPHPC_01366	1.5e-85	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
MEDFPHPC_01367	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
MEDFPHPC_01368	1.04e-209	-	-	-	C	-	-	-	Aldo keto reductase
MEDFPHPC_01369	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
MEDFPHPC_01370	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MEDFPHPC_01371	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MEDFPHPC_01372	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
MEDFPHPC_01373	4.71e-47	-	-	-	-	-	-	-	-
MEDFPHPC_01374	2.57e-273	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
MEDFPHPC_01375	6.32e-228	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_01376	4.3e-84	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
MEDFPHPC_01377	8.07e-102	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
MEDFPHPC_01378	4.45e-149	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MEDFPHPC_01379	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
MEDFPHPC_01380	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
MEDFPHPC_01381	1.55e-223	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEDFPHPC_01382	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
MEDFPHPC_01383	1.67e-104	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MEDFPHPC_01384	3.87e-269	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
MEDFPHPC_01385	9.11e-196	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
MEDFPHPC_01386	9.32e-182	yycI	-	-	S	-	-	-	YycH protein
MEDFPHPC_01387	2.34e-302	yycH	-	-	S	-	-	-	YycH protein
MEDFPHPC_01388	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEDFPHPC_01389	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
MEDFPHPC_01392	6.3e-81	-	-	-	-	-	-	-	-
MEDFPHPC_01393	2.96e-266	-	-	-	E	-	-	-	Major Facilitator Superfamily
MEDFPHPC_01394	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
MEDFPHPC_01395	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MEDFPHPC_01396	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
MEDFPHPC_01397	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MEDFPHPC_01398	3.58e-153	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MEDFPHPC_01399	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
MEDFPHPC_01400	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEDFPHPC_01401	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MEDFPHPC_01402	9.75e-256	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MEDFPHPC_01403	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
MEDFPHPC_01404	2.16e-262	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MEDFPHPC_01405	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MEDFPHPC_01407	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family
MEDFPHPC_01408	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MEDFPHPC_01409	4.1e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEDFPHPC_01410	2.27e-191	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
MEDFPHPC_01411	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MEDFPHPC_01412	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MEDFPHPC_01413	9.86e-74	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MEDFPHPC_01414	5.31e-285	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MEDFPHPC_01415	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
MEDFPHPC_01416	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEDFPHPC_01417	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MEDFPHPC_01418	1.16e-146	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
MEDFPHPC_01419	1.98e-202	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
MEDFPHPC_01420	1.01e-111	-	-	-	L	-	-	-	nuclease
MEDFPHPC_01421	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MEDFPHPC_01422	8.9e-48	-	-	-	-	-	-	-	-
MEDFPHPC_01423	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
MEDFPHPC_01424	6.45e-240	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
MEDFPHPC_01425	2.63e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEDFPHPC_01426	1.41e-209	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MEDFPHPC_01427	2.9e-158	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01428	3.05e-99	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
MEDFPHPC_01429	3.55e-61	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
MEDFPHPC_01430	2.43e-299	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEDFPHPC_01431	3.21e-213	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEDFPHPC_01432	9.16e-35	-	-	-	-	-	-	-	-
MEDFPHPC_01433	1.98e-280	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01434	3.97e-137	-	-	-	-	-	-	-	-
MEDFPHPC_01435	9.3e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MEDFPHPC_01436	1.76e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MEDFPHPC_01437	7.49e-74	-	-	-	-	-	-	-	-
MEDFPHPC_01438	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
MEDFPHPC_01440	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
MEDFPHPC_01441	8.13e-150	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
MEDFPHPC_01442	3.17e-260	-	-	-	S	-	-	-	associated with various cellular activities
MEDFPHPC_01443	1.55e-264	-	-	-	S	-	-	-	Putative metallopeptidase domain
MEDFPHPC_01444	1.65e-58	-	-	-	-	-	-	-	-
MEDFPHPC_01445	3.5e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
MEDFPHPC_01446	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
MEDFPHPC_01447	1.16e-118	ymdB	-	-	S	-	-	-	Macro domain protein
MEDFPHPC_01448	1.02e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MEDFPHPC_01449	1.66e-100	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEDFPHPC_01450	2.44e-216	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_01451	4.33e-69	-	-	-	-	-	-	-	-
MEDFPHPC_01452	1.8e-179	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
MEDFPHPC_01453	4.27e-155	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
MEDFPHPC_01454	5.64e-172	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01455	1.21e-48	-	-	-	-	-	-	-	-
MEDFPHPC_01456	2.74e-122	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
MEDFPHPC_01457	5.38e-182	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
MEDFPHPC_01458	9.04e-230	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
MEDFPHPC_01459	7.25e-286	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MEDFPHPC_01460	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
MEDFPHPC_01461	1.1e-228	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
MEDFPHPC_01462	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
MEDFPHPC_01463	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
MEDFPHPC_01464	1.39e-171	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01465	6.15e-161	-	-	-	S	-	-	-	Membrane
MEDFPHPC_01466	1.29e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MEDFPHPC_01467	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
MEDFPHPC_01468	5.62e-228	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MEDFPHPC_01469	3.03e-128	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_01470	1.1e-179	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MEDFPHPC_01471	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
MEDFPHPC_01472	2.13e-106	usp5	-	-	T	-	-	-	universal stress protein
MEDFPHPC_01473	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MEDFPHPC_01474	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MEDFPHPC_01475	2.08e-265	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
MEDFPHPC_01476	1.49e-97	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
MEDFPHPC_01477	7.2e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
MEDFPHPC_01478	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
MEDFPHPC_01479	3.97e-115	-	-	-	GM	-	-	-	epimerase
MEDFPHPC_01480	9.84e-112	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
MEDFPHPC_01481	1.16e-183	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01482	9.3e-71	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01483	1.25e-197	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
MEDFPHPC_01484	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
MEDFPHPC_01485	5.15e-165	-	-	-	-	-	-	-	-
MEDFPHPC_01486	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MEDFPHPC_01487	3.13e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
MEDFPHPC_01488	1.62e-186	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MEDFPHPC_01489	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
MEDFPHPC_01490	0.0	potE	-	-	E	-	-	-	Amino Acid
MEDFPHPC_01491	8.77e-237	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
MEDFPHPC_01492	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
MEDFPHPC_01493	3.52e-25	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01494	2.26e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_01495	3.57e-59	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01496	2.34e-286	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01497	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEDFPHPC_01498	4.9e-167	-	-	-	K	ko:K02538,ko:K03483,ko:K03491	-	ko00000,ko03000	PRD domain
MEDFPHPC_01499	2.33e-19	-	-	-	H	-	-	-	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEDFPHPC_01500	9.93e-69	-	2.7.1.202	-	G	ko:K02768	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEDFPHPC_01501	1.55e-53	-	2.7.1.202	-	G	ko:K02769	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system, Lactose/Cellobiose specific IIB subunit
MEDFPHPC_01502	2.27e-183	-	-	-	G	ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	Phosphotransferase System
MEDFPHPC_01503	1.21e-138	-	-	-	G	ko:K17195	ko00051,ko01120,map00051,map01120	ko00000,ko00001,ko01000	Ribulose-phosphate 3 epimerase family
MEDFPHPC_01504	2.37e-165	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MEDFPHPC_01505	4.36e-162	-	-	-	G	ko:K03483	-	ko00000,ko03000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEDFPHPC_01506	5.41e-56	-	2.7.1.194	-	G	ko:K02821	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MEDFPHPC_01507	7.59e-54	ulaB	2.7.1.194	-	G	ko:K02822	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	Phosphotransferase system galactitol-specific IIB component
MEDFPHPC_01508	1.58e-244	ulaA	-	-	S	ko:K03475	ko00053,ko01100,ko01120,ko02060,map00053,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko02000	PTS system sugar-specific permease component
MEDFPHPC_01509	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEDFPHPC_01510	5.24e-159	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MEDFPHPC_01511	2.3e-173	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
MEDFPHPC_01512	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MEDFPHPC_01513	1.69e-11	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MEDFPHPC_01514	1.2e-268	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
MEDFPHPC_01515	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
MEDFPHPC_01517	7.24e-97	uspA3	-	-	T	-	-	-	universal stress protein
MEDFPHPC_01518	1.79e-77	-	-	-	-	-	-	-	-
MEDFPHPC_01519	4.83e-10	-	-	-	-	-	-	-	-
MEDFPHPC_01520	1.84e-201	-	-	-	-	-	-	-	-
MEDFPHPC_01521	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
MEDFPHPC_01522	1.34e-233	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
MEDFPHPC_01523	2.71e-95	-	-	-	O	-	-	-	OsmC-like protein
MEDFPHPC_01524	3.09e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
MEDFPHPC_01525	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
MEDFPHPC_01526	3.57e-22	-	-	-	-	-	-	-	-
MEDFPHPC_01527	8.34e-147	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
MEDFPHPC_01528	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01529	6.78e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MEDFPHPC_01530	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
MEDFPHPC_01531	1.24e-234	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
MEDFPHPC_01532	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
MEDFPHPC_01533	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
MEDFPHPC_01534	5.42e-128	dpsB	-	-	P	-	-	-	Belongs to the Dps family
MEDFPHPC_01535	3.13e-141	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
MEDFPHPC_01536	6.07e-40	-	-	-	-	-	-	-	-
MEDFPHPC_01537	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEDFPHPC_01538	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
MEDFPHPC_01539	1.18e-191	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
MEDFPHPC_01540	5.81e-76	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MEDFPHPC_01541	1.36e-194	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
MEDFPHPC_01542	4.59e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
MEDFPHPC_01543	1.53e-210	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
MEDFPHPC_01544	3.51e-183	yceF	-	-	P	ko:K05794	-	ko00000	membrane
MEDFPHPC_01545	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MEDFPHPC_01546	5.5e-210	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MEDFPHPC_01547	3.31e-205	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
MEDFPHPC_01548	2.82e-234	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
MEDFPHPC_01549	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
MEDFPHPC_01550	5.36e-215	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
MEDFPHPC_01551	2.36e-198	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MEDFPHPC_01552	2.22e-67	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
MEDFPHPC_01553	1.79e-285	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
MEDFPHPC_01554	5.36e-170	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01555	3.09e-192	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
MEDFPHPC_01556	1.49e-226	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
MEDFPHPC_01557	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MEDFPHPC_01558	1.91e-261	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
MEDFPHPC_01560	3.38e-140	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
MEDFPHPC_01561	7.8e-107	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
MEDFPHPC_01562	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MEDFPHPC_01563	1.79e-215	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
MEDFPHPC_01564	1.15e-232	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
MEDFPHPC_01565	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
MEDFPHPC_01566	2.7e-145	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
MEDFPHPC_01567	2.73e-227	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
MEDFPHPC_01568	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MEDFPHPC_01569	5.72e-261	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
MEDFPHPC_01570	8.63e-93	-	-	-	F	-	-	-	Nudix hydrolase
MEDFPHPC_01571	3.22e-135	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
MEDFPHPC_01572	1.03e-109	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
MEDFPHPC_01573	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
MEDFPHPC_01574	1.66e-215	-	-	-	-	-	-	-	-
MEDFPHPC_01575	2.66e-249	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
MEDFPHPC_01576	2.35e-119	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
MEDFPHPC_01577	2.51e-309	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
MEDFPHPC_01578	1.24e-101	-	-	-	-	-	-	-	-
MEDFPHPC_01580	2.32e-235	ydaM	-	-	M	-	-	-	Glycosyl transferase family group 2
MEDFPHPC_01581	6.93e-154	-	-	-	G	-	-	-	Glycosyl hydrolases family 8
MEDFPHPC_01582	1.71e-176	-	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	UDP-N-acetylglucosamine 2-epimerase
MEDFPHPC_01583	1.75e-134	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MEDFPHPC_01584	6.88e-129	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01585	5.23e-69	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01586	0.0	-	-	-	E	-	-	-	amino acid
MEDFPHPC_01587	1.19e-171	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
MEDFPHPC_01588	2.43e-263	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MEDFPHPC_01589	6.6e-294	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MEDFPHPC_01590	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
MEDFPHPC_01591	5.9e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
MEDFPHPC_01592	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
MEDFPHPC_01593	1.93e-204	-	-	-	EG	-	-	-	EamA-like transporter family
MEDFPHPC_01594	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MEDFPHPC_01595	1.5e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
MEDFPHPC_01596	8.35e-137	-	-	-	K	-	-	-	acetyltransferase
MEDFPHPC_01597	4.62e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
MEDFPHPC_01598	2.55e-165	sptS	-	-	T	-	-	-	Histidine kinase
MEDFPHPC_01599	6.69e-101	dltr	-	-	K	-	-	-	response regulator
MEDFPHPC_01600	7.85e-145	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
MEDFPHPC_01601	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
MEDFPHPC_01602	1.72e-242	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_01603	3.01e-146	-	-	-	-	-	-	-	-
MEDFPHPC_01604	1.95e-134	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
MEDFPHPC_01605	6.7e-72	-	-	-	K	-	-	-	Helix-turn-helix domain
MEDFPHPC_01606	8.61e-50	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
MEDFPHPC_01607	2.01e-96	-	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Arginase family
MEDFPHPC_01608	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01609	1.8e-259	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01610	2.12e-77	-	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MEDFPHPC_01611	9.57e-43	-	2.2.1.7	-	HI	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	1-deoxy-D-xylulose-5-phosphate synthase
MEDFPHPC_01612	1.32e-155	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEDFPHPC_01613	0.0	yhcA	-	-	V	ko:K02003,ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01614	1.69e-72	-	-	-	S	-	-	-	FMN_bind
MEDFPHPC_01615	7.32e-83	-	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MEDFPHPC_01616	3.07e-166	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
MEDFPHPC_01617	1.03e-66	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
MEDFPHPC_01618	5.88e-68	cpg2	3.4.17.11	-	E	ko:K01295	-	ko00000,ko01000,ko01002	Peptidase dimerisation domain
MEDFPHPC_01619	1.54e-50	-	-	-	M	-	-	-	Rib/alpha-like repeat
MEDFPHPC_01620	1.14e-290	ylbB	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
MEDFPHPC_01621	7.02e-124	-	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01622	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEDFPHPC_01623	1.21e-296	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
MEDFPHPC_01624	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
MEDFPHPC_01625	5.52e-68	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
MEDFPHPC_01626	1.63e-196	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
MEDFPHPC_01627	2.09e-35	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MEDFPHPC_01628	9.53e-30	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MEDFPHPC_01629	1.72e-316	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
MEDFPHPC_01630	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MEDFPHPC_01632	9.15e-194	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
MEDFPHPC_01633	3.77e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
MEDFPHPC_01634	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
MEDFPHPC_01635	3.85e-261	-	-	-	EGP	-	-	-	Major Facilitator
MEDFPHPC_01636	1.73e-271	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
MEDFPHPC_01637	8.18e-163	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
MEDFPHPC_01638	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
MEDFPHPC_01639	1.44e-73	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MEDFPHPC_01640	1.59e-241	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
MEDFPHPC_01641	3.49e-169	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
MEDFPHPC_01642	3.88e-22	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MEDFPHPC_01643	6.2e-56	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
MEDFPHPC_01644	4.89e-105	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
MEDFPHPC_01645	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
MEDFPHPC_01646	2.42e-122	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
MEDFPHPC_01647	3.07e-135	-	-	-	NU	-	-	-	mannosyl-glycoprotein
MEDFPHPC_01648	1.09e-218	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
MEDFPHPC_01649	1.4e-53	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
MEDFPHPC_01650	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01651	2.51e-298	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01652	1.74e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
MEDFPHPC_01653	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MEDFPHPC_01654	4.14e-121	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
MEDFPHPC_01655	1.79e-49	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_01656	2.72e-164	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MEDFPHPC_01657	7.18e-160	rcfB	-	-	K	-	-	-	Crp-like helix-turn-helix domain
MEDFPHPC_01658	1.01e-304	larA	5.1.2.1	-	S	ko:K22373	ko00620,map00620	ko00000,ko00001,ko01000	Domain of unknown function (DUF2088)
MEDFPHPC_01659	2.75e-167	larB	-	-	S	ko:K06898	-	ko00000	AIR carboxylase
MEDFPHPC_01660	1.97e-296	larC	4.99.1.12	-	S	ko:K09121	-	ko00000,ko01000	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MEDFPHPC_01661	1.56e-165	glpF	-	-	U	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
MEDFPHPC_01662	4.65e-191	larE	-	-	S	ko:K06864	-	ko00000	NAD synthase
MEDFPHPC_01663	1.45e-234	hoxN	-	-	U	ko:K07241	-	ko00000,ko02000	High-affinity nickel-transport protein
MEDFPHPC_01664	7.82e-50	-	-	-	S	-	-	-	Cytochrome B5
MEDFPHPC_01667	7.07e-286	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MEDFPHPC_01668	3.13e-122	-	-	-	K	-	-	-	transcriptional regulator
MEDFPHPC_01669	9.11e-92	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
MEDFPHPC_01670	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
MEDFPHPC_01671	7.63e-72	-	-	-	S	-	-	-	MazG-like family
MEDFPHPC_01672	2.09e-136	-	-	-	I	-	-	-	PAP2 superfamily
MEDFPHPC_01673	1.78e-151	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MEDFPHPC_01674	2.07e-79	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
MEDFPHPC_01675	9.69e-122	-	-	-	-	-	-	-	-
MEDFPHPC_01676	4.04e-284	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
MEDFPHPC_01677	3.86e-193	-	-	-	V	-	-	-	Beta-lactamase enzyme family
MEDFPHPC_01678	0.0	potE	-	-	E	-	-	-	Amino Acid
MEDFPHPC_01679	1.15e-279	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01681	8.82e-141	-	-	-	-	-	-	-	-
MEDFPHPC_01682	9.11e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
MEDFPHPC_01683	5.73e-210	-	-	-	K	-	-	-	LysR substrate binding domain
MEDFPHPC_01684	3.44e-09	-	-	-	GM	-	-	-	NAD(P)H-binding
MEDFPHPC_01685	1.28e-58	-	-	-	GM	-	-	-	NmrA-like family
MEDFPHPC_01686	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
MEDFPHPC_01687	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
MEDFPHPC_01688	2.36e-249	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
MEDFPHPC_01689	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
MEDFPHPC_01690	2.18e-138	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MEDFPHPC_01692	4.3e-34	nlhH_1	-	-	I	ko:K01066	-	ko00000,ko01000	acetylesterase activity
MEDFPHPC_01693	2.24e-98	mleR	-	-	K	-	-	-	LysR family
MEDFPHPC_01694	3.78e-290	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
MEDFPHPC_01695	2.47e-234	XK27_09615	1.5.1.36	-	S	ko:K19784,ko:K22393	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	reductase
MEDFPHPC_01696	3.53e-117	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MEDFPHPC_01697	9.29e-283	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MEDFPHPC_01698	7.48e-269	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
MEDFPHPC_01699	4.12e-287	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
MEDFPHPC_01700	2.63e-208	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
MEDFPHPC_01701	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
MEDFPHPC_01702	6.93e-155	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
MEDFPHPC_01703	2.62e-239	-	-	-	I	-	-	-	Alpha beta
MEDFPHPC_01704	1.66e-137	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
MEDFPHPC_01705	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEDFPHPC_01707	2.99e-217	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
MEDFPHPC_01708	0.0	araB	2.7.1.16	-	G	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	carbohydrate kinase FGGY
MEDFPHPC_01709	1.06e-175	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MEDFPHPC_01710	2.07e-260	araR	-	-	K	ko:K02103	-	ko00000,ko03000	Transcriptional regulator
MEDFPHPC_01711	1.57e-314	araP	-	-	U	-	-	-	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MEDFPHPC_01712	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
MEDFPHPC_01713	1.3e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
MEDFPHPC_01714	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
MEDFPHPC_01715	7.71e-94	-	-	-	K	-	-	-	MerR HTH family regulatory protein
MEDFPHPC_01716	1.15e-77	-	-	-	-	-	-	-	-
MEDFPHPC_01717	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MEDFPHPC_01718	1.87e-283	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MEDFPHPC_01719	5.89e-29	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
MEDFPHPC_01720	1.44e-109	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MEDFPHPC_01721	2.24e-140	-	-	-	S	-	-	-	VIT family
MEDFPHPC_01722	9.24e-151	-	-	-	S	-	-	-	membrane
MEDFPHPC_01723	1.25e-208	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
MEDFPHPC_01724	8.41e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
MEDFPHPC_01725	1.72e-40	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
MEDFPHPC_01726	7.5e-159	-	-	-	S	-	-	-	Putative threonine/serine exporter
MEDFPHPC_01727	4.05e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
MEDFPHPC_01728	2.47e-146	-	-	-	I	-	-	-	phosphatase
MEDFPHPC_01729	2.43e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
MEDFPHPC_01731	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
MEDFPHPC_01732	6.66e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MEDFPHPC_01738	5.13e-115	-	-	-	IQ	-	-	-	reductase
MEDFPHPC_01739	5.86e-190	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MEDFPHPC_01740	3.92e-68	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
MEDFPHPC_01741	2.77e-92	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
MEDFPHPC_01742	2.01e-46	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
MEDFPHPC_01743	1.05e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
MEDFPHPC_01744	4.84e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
MEDFPHPC_01745	2.65e-245	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
MEDFPHPC_01746	3.54e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01747	6.36e-103	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
MEDFPHPC_01748	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MEDFPHPC_01749	4.92e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEDFPHPC_01750	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEDFPHPC_01751	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEDFPHPC_01752	4.84e-172	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
MEDFPHPC_01753	1.01e-273	-	-	-	-	-	-	-	-
MEDFPHPC_01754	1.77e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
MEDFPHPC_01755	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MEDFPHPC_01756	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MEDFPHPC_01757	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MEDFPHPC_01758	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
MEDFPHPC_01759	8.37e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MEDFPHPC_01760	3.16e-137	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
MEDFPHPC_01761	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MEDFPHPC_01762	1.35e-202	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MEDFPHPC_01763	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MEDFPHPC_01764	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MEDFPHPC_01765	2.49e-149	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MEDFPHPC_01766	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MEDFPHPC_01767	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
MEDFPHPC_01768	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MEDFPHPC_01769	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MEDFPHPC_01770	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MEDFPHPC_01771	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MEDFPHPC_01772	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MEDFPHPC_01773	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MEDFPHPC_01774	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MEDFPHPC_01775	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MEDFPHPC_01776	2.08e-112	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MEDFPHPC_01777	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
MEDFPHPC_01778	4.09e-91	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
MEDFPHPC_01779	1.36e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MEDFPHPC_01780	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MEDFPHPC_01781	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MEDFPHPC_01782	2.6e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
MEDFPHPC_01783	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MEDFPHPC_01784	1.62e-83	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MEDFPHPC_01785	4.94e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MEDFPHPC_01786	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
MEDFPHPC_01787	2.91e-191	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEDFPHPC_01788	2.06e-201	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEDFPHPC_01789	5.57e-177	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MEDFPHPC_01790	6.37e-185	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MEDFPHPC_01791	4.58e-103	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MEDFPHPC_01792	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
MEDFPHPC_01793	1.61e-40	-	-	-	S	-	-	-	interspecies interaction between organisms
MEDFPHPC_01794	8.74e-21	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
MEDFPHPC_01795	3.01e-162	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01796	7.78e-62	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01797	2.92e-38	-	-	-	S	-	-	-	interspecies interaction between organisms
MEDFPHPC_01798	2.48e-177	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
MEDFPHPC_01799	1.58e-140	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
MEDFPHPC_01800	3.74e-130	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MEDFPHPC_01801	1.76e-278	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MEDFPHPC_01802	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
MEDFPHPC_01803	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MEDFPHPC_01804	6.46e-232	camS	-	-	S	-	-	-	sex pheromone
MEDFPHPC_01805	2.85e-64	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEDFPHPC_01806	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MEDFPHPC_01807	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MEDFPHPC_01808	2.07e-236	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
MEDFPHPC_01809	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MEDFPHPC_01810	2.76e-109	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
MEDFPHPC_01811	1.97e-111	-	-	-	K	-	-	-	Psort location CytoplasmicMembrane, score
MEDFPHPC_01812	6.46e-157	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
MEDFPHPC_01813	2.3e-80	-	-	-	S	-	-	-	YjbR
MEDFPHPC_01815	2.41e-156	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MEDFPHPC_01816	5.16e-77	-	-	-	S	-	-	-	Domain of unknown function (DUF3841)
MEDFPHPC_01817	3.17e-65	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_01818	8.93e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_01820	1.69e-215	kdpA	-	-	P	-	-	-	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MEDFPHPC_01821	8.3e-178	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MEDFPHPC_01822	6.56e-136	kdpB	3.6.3.12	-	P	ko:K01547	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MEDFPHPC_01823	3.07e-45	kdpC	3.6.3.12	-	P	ko:K01548	ko02020,map02020	ko00000,ko00001,ko01000	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
MEDFPHPC_01824	2.06e-161	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
MEDFPHPC_01825	7.78e-222	kdpD	2.7.13.3	-	T	ko:K07646	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEDFPHPC_01826	5.72e-81	kdpE	-	-	KT	ko:K07667	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	transcriptional regulatory protein
MEDFPHPC_01827	2.05e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
MEDFPHPC_01828	1.11e-109	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MEDFPHPC_01829	0.0	trePP	2.4.1.216, 2.4.1.8	GH65	G	ko:K00691,ko:K03731	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycosyl hydrolase family 65 central catalytic domain
MEDFPHPC_01830	2.02e-35	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
MEDFPHPC_01831	4.56e-168	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
MEDFPHPC_01832	1.76e-110	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_01833	2.69e-23	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_01834	3.79e-19	-	-	-	L	-	-	-	PFAM Integrase catalytic region
MEDFPHPC_01835	1.72e-21	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_01836	9.37e-58	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_01837	1.36e-22	-	-	-	-	-	-	-	-
MEDFPHPC_01838	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
MEDFPHPC_01839	3.37e-96	-	-	-	S	-	-	-	cog cog1302
MEDFPHPC_01840	5.24e-33	-	-	-	S	-	-	-	Small integral membrane protein (DUF2273)
MEDFPHPC_01841	6.51e-122	-	-	-	-	-	-	-	-
MEDFPHPC_01842	1.81e-112	-	-	-	L	ko:K07497	-	ko00000	PFAM Integrase catalytic region
MEDFPHPC_01843	1.86e-24	-	-	-	L	ko:K07483	-	ko00000	PFAM transposase IS3 IS911 family protein
MEDFPHPC_01844	1.23e-233	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
MEDFPHPC_01847	1.31e-181	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
MEDFPHPC_01849	6.85e-244	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
MEDFPHPC_01851	9.4e-97	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
MEDFPHPC_01852	3.19e-44	ddaH	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	dimethylargininase activity
MEDFPHPC_01853	1.3e-114	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
MEDFPHPC_01854	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
MEDFPHPC_01855	7.65e-39	-	-	-	S	ko:K08987	-	ko00000	membrane
MEDFPHPC_01856	3.68e-67	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
MEDFPHPC_01857	3.11e-68	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
MEDFPHPC_01858	2.65e-149	-	-	-	Q	-	-	-	Methyltransferase domain
MEDFPHPC_01860	1.85e-131	-	-	-	S	-	-	-	CAAX protease self-immunity
MEDFPHPC_01861	4.71e-124	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MEDFPHPC_01863	3.21e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_01864	2.8e-262	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
MEDFPHPC_01865	4.82e-20	-	-	-	K	-	-	-	Cupin domain
MEDFPHPC_01866	1.39e-130	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
MEDFPHPC_01867	4.91e-271	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
MEDFPHPC_01868	7.36e-135	-	-	-	-	-	-	-	-
MEDFPHPC_01869	2.41e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
MEDFPHPC_01870	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
MEDFPHPC_01871	1.43e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
MEDFPHPC_01872	5.83e-177	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
MEDFPHPC_01873	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
MEDFPHPC_01874	2.61e-205	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
MEDFPHPC_01875	7.35e-134	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
MEDFPHPC_01876	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
MEDFPHPC_01877	2.18e-243	mocA	-	-	S	-	-	-	Oxidoreductase
MEDFPHPC_01878	1.37e-306	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
MEDFPHPC_01881	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
MEDFPHPC_01882	1.66e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
MEDFPHPC_01883	1.17e-214	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
MEDFPHPC_01884	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
MEDFPHPC_01885	1.61e-189	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MEDFPHPC_01886	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
MEDFPHPC_01888	2.39e-187	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
MEDFPHPC_01889	4.95e-152	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
MEDFPHPC_01890	2.33e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
MEDFPHPC_01891	2.37e-117	cps3F	-	-	-	-	-	-	-
MEDFPHPC_01892	3.15e-08	epsB	-	-	M	-	-	-	biosynthesis protein
MEDFPHPC_01893	4.65e-279	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
MEDFPHPC_01894	4.33e-257	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
MEDFPHPC_01895	7.66e-87	-	-	-	S	-	-	-	enterobacterial common antigen metabolic process
MEDFPHPC_01896	6.98e-91	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MEDFPHPC_01897	5.4e-88	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
MEDFPHPC_01898	3.93e-290	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_01899	2.02e-217	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01900	3.3e-75	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_01901	5.95e-152	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_01902	5.31e-235	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
MEDFPHPC_01904	4.66e-23	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MEDFPHPC_01905	9.16e-53	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MEDFPHPC_01906	2.14e-51	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
MEDFPHPC_01907	2.48e-52	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
MEDFPHPC_01908	2.34e-36	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MEDFPHPC_01909	4.8e-59	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
MEDFPHPC_01910	1.95e-79	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
MEDFPHPC_01911	2.15e-10	-	-	-	-	-	-	-	-
MEDFPHPC_01912	3.81e-203	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
MEDFPHPC_01913	1.13e-213	yueF	-	-	S	-	-	-	AI-2E family transporter
MEDFPHPC_01914	5.22e-211	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
MEDFPHPC_01915	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MEDFPHPC_01916	6.47e-120	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MEDFPHPC_01917	2.99e-126	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
MEDFPHPC_01918	4.38e-100	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
MEDFPHPC_01919	1.47e-216	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MEDFPHPC_01920	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
MEDFPHPC_01921	9.46e-201	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_01924	1.6e-313	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
MEDFPHPC_01925	4.26e-206	-	-	-	EG	-	-	-	EamA-like transporter family
MEDFPHPC_01926	4.96e-175	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MEDFPHPC_01927	9.48e-182	-	-	-	G	-	-	-	MucBP domain
MEDFPHPC_01928	8.07e-126	-	-	-	S	-	-	-	Pfam:DUF3816
MEDFPHPC_01929	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MEDFPHPC_01930	7.08e-142	pncA	-	-	Q	-	-	-	Isochorismatase family
MEDFPHPC_01931	4.63e-162	-	-	-	F	-	-	-	NUDIX domain
MEDFPHPC_01932	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
MEDFPHPC_01934	1.24e-52	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
MEDFPHPC_01935	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MEDFPHPC_01936	2.56e-290	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MEDFPHPC_01937	5.2e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
MEDFPHPC_01938	9.34e-230	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MEDFPHPC_01939	1.9e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
MEDFPHPC_01942	8.34e-101	-	-	-	-	-	-	-	-
MEDFPHPC_01953	4.13e-21	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
MEDFPHPC_01954	3.93e-182	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
MEDFPHPC_01955	7.19e-142	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
MEDFPHPC_01956	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
MEDFPHPC_01957	1.22e-143	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MEDFPHPC_01958	1.44e-197	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
MEDFPHPC_01959	1.07e-300	-	-	-	F	ko:K03458	-	ko00000	Permease
MEDFPHPC_01960	1.62e-87	-	-	-	M	-	-	-	LysM domain protein
MEDFPHPC_01961	4.21e-111	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
MEDFPHPC_01962	2.29e-101	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
MEDFPHPC_01963	1.55e-152	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
MEDFPHPC_01966	3.91e-31	-	-	-	-	-	-	-	-
MEDFPHPC_01967	2.23e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
MEDFPHPC_01968	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
MEDFPHPC_01969	0.0	-	-	-	EGP	-	-	-	Major Facilitator
MEDFPHPC_01970	1.12e-121	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
MEDFPHPC_01971	3.23e-64	-	-	-	-	-	-	-	-
MEDFPHPC_01972	2.97e-268	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MEDFPHPC_01973	2.1e-177	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MEDFPHPC_01974	5.12e-285	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MEDFPHPC_01975	6.62e-160	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
MEDFPHPC_01976	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
MEDFPHPC_01977	4.03e-56	-	-	-	-	-	-	-	-
MEDFPHPC_01978	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
MEDFPHPC_01979	9.22e-37	-	-	-	S	-	-	-	Domain of unknown function DUF302
MEDFPHPC_01980	8.92e-194	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MEDFPHPC_01981	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
MEDFPHPC_01982	6.74e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
MEDFPHPC_01983	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
MEDFPHPC_01984	1.59e-20	-	-	-	L	ko:K07482	-	ko00000	PFAM Integrase, catalytic core
MEDFPHPC_01985	1.04e-236	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MEDFPHPC_01986	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
MEDFPHPC_01987	1.11e-139	-	-	-	-	-	-	-	-
MEDFPHPC_01988	5.25e-234	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
MEDFPHPC_01989	2.89e-152	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
MEDFPHPC_01990	2.44e-82	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MEDFPHPC_01991	4.35e-120	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MEDFPHPC_01992	3.23e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
MEDFPHPC_01993	1.4e-300	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
MEDFPHPC_01994	1.07e-134	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
MEDFPHPC_01995	3.48e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
MEDFPHPC_01997	4.43e-49	-	-	-	-	-	-	-	-
MEDFPHPC_01999	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
MEDFPHPC_02000	2.48e-10	-	-	-	L	-	-	-	MULE transposase domain
MEDFPHPC_02001	1.94e-303	dinF	-	-	V	-	-	-	MatE
MEDFPHPC_02002	3.07e-91	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
MEDFPHPC_02004	2e-93	ysnF	-	-	S	-	-	-	Heat induced stress protein YflT
MEDFPHPC_02005	4.8e-54	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_02006	1.05e-74	-	-	-	L	-	-	-	Helix-turn-helix domain
MEDFPHPC_02007	4.77e-216	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
MEDFPHPC_02008	1.36e-212	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
MEDFPHPC_02009	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_02010	1.4e-90	-	-	-	S	-	-	-	Nuclease-related domain
MEDFPHPC_02011	3.18e-194	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
MEDFPHPC_02012	1.99e-47	-	-	-	L	-	-	-	Transposase DDE domain
MEDFPHPC_02013	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
MEDFPHPC_02014	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
MEDFPHPC_02015	5.02e-228	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
MEDFPHPC_02016	5.47e-191	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MEDFPHPC_02018	1.23e-100	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
MEDFPHPC_02019	1.5e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
MEDFPHPC_02020	1.74e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
MEDFPHPC_02021	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MEDFPHPC_02022	6.83e-76	-	-	-	S	-	-	-	Small secreted protein
MEDFPHPC_02023	8.85e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
MEDFPHPC_02024	1.11e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEDFPHPC_02025	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
MEDFPHPC_02026	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
MEDFPHPC_02027	3.83e-177	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
MEDFPHPC_02028	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MEDFPHPC_02029	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MEDFPHPC_02030	1.39e-135	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MEDFPHPC_02031	1.64e-103	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MEDFPHPC_02032	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
MEDFPHPC_02033	3.11e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
MEDFPHPC_02034	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MEDFPHPC_02035	2.49e-35	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
MEDFPHPC_02036	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MEDFPHPC_02038	1.89e-122	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
MEDFPHPC_02039	6.04e-271	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
MEDFPHPC_02040	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
MEDFPHPC_02041	5.4e-119	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MEDFPHPC_02042	2.25e-144	yqeK	-	-	H	-	-	-	Hydrolase, HD family
MEDFPHPC_02043	5.63e-77	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MEDFPHPC_02044	2.47e-173	yqeM	-	-	Q	-	-	-	Methyltransferase
MEDFPHPC_02045	3.78e-270	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
MEDFPHPC_02046	9.71e-127	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
MEDFPHPC_02047	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
MEDFPHPC_02048	5.62e-155	csrR	-	-	K	-	-	-	response regulator
MEDFPHPC_02049	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
MEDFPHPC_02050	2.56e-296	-	-	-	V	-	-	-	MatE
MEDFPHPC_02051	5.31e-90	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
MEDFPHPC_02052	9.66e-198	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MEDFPHPC_02053	8.13e-62	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
MEDFPHPC_02054	5.9e-177	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MEDFPHPC_02055	5.12e-117	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
MEDFPHPC_02056	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
MEDFPHPC_02057	2.58e-252	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MEDFPHPC_02058	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MEDFPHPC_02059	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
MEDFPHPC_02060	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MEDFPHPC_02061	0.0	-	-	-	S	-	-	-	membrane
MEDFPHPC_02062	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
MEDFPHPC_02063	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
MEDFPHPC_02064	5.19e-127	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MEDFPHPC_02065	4.24e-135	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
MEDFPHPC_02066	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
MEDFPHPC_02067	8.69e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
MEDFPHPC_02068	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
MEDFPHPC_02069	3.51e-33	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
MEDFPHPC_02070	1.48e-219	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MEDFPHPC_02071	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
MEDFPHPC_02072	4.76e-19	-	-	-	-	-	-	-	-
MEDFPHPC_02073	1.34e-201	-	-	-	-	-	-	-	-
MEDFPHPC_02074	3.19e-224	-	-	-	-	-	-	-	-
MEDFPHPC_02075	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
MEDFPHPC_02076	2.05e-256	-	-	-	S	-	-	-	Phage integrase family
MEDFPHPC_02079	1e-29	-	-	-	-	-	-	-	-
MEDFPHPC_02080	3.24e-90	-	-	-	-	-	-	-	-
MEDFPHPC_02081	6.94e-70	-	-	-	S	-	-	-	sequence-specific DNA binding
MEDFPHPC_02082	1.66e-06	-	-	-	K	ko:K21498	-	ko00000,ko02048	addiction module antidote protein, HigA family
MEDFPHPC_02083	6.31e-179	-	-	-	S	-	-	-	DNA binding
MEDFPHPC_02096	2.31e-11	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
MEDFPHPC_02099	2.05e-91	-	-	-	S	-	-	-	AAA domain
MEDFPHPC_02100	3.31e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
MEDFPHPC_02101	3.07e-90	-	-	-	S	-	-	-	Putative HNHc nuclease
MEDFPHPC_02102	4.46e-83	-	-	-	L	-	-	-	DnaD domain protein
MEDFPHPC_02103	2.66e-54	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
MEDFPHPC_02106	4.41e-47	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
MEDFPHPC_02110	1.21e-66	-	-	-	K	-	-	-	Protein of unknown function (DUF4065)
MEDFPHPC_02111	6.64e-44	doc	-	-	S	ko:K07341	-	ko00000,ko02048	Fic/DOC family
MEDFPHPC_02112	7.13e-42	-	-	-	L	-	-	-	HNH nucleases
MEDFPHPC_02113	9.42e-53	-	-	-	L	-	-	-	Phage terminase, small subunit
MEDFPHPC_02114	0.0	-	-	-	S	-	-	-	Phage Terminase
MEDFPHPC_02116	5.52e-180	-	-	-	S	-	-	-	portal protein
MEDFPHPC_02117	1.22e-99	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
MEDFPHPC_02118	1.14e-153	-	-	-	S	-	-	-	Phage capsid family
MEDFPHPC_02119	5.01e-39	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
MEDFPHPC_02120	1.79e-43	-	-	-	S	-	-	-	Phage head-tail joining protein
MEDFPHPC_02121	3.23e-25	-	-	-	-	-	-	-	-
MEDFPHPC_02122	1.11e-30	-	-	-	-	-	-	-	-
MEDFPHPC_02123	8.91e-64	-	-	-	S	-	-	-	Phage tail tube protein
MEDFPHPC_02125	1.25e-301	-	-	-	L	-	-	-	Phage tail tape measure protein TP901
MEDFPHPC_02126	2.54e-101	-	-	-	S	-	-	-	Phage tail protein
MEDFPHPC_02127	3.02e-185	rny	-	-	D	ko:K12088,ko:K18682	ko03018,ko05120,map03018,map05120	ko00000,ko00001,ko00002,ko01000,ko02044,ko03019	peptidase
MEDFPHPC_02128	1.4e-64	spoIVFA	-	GT2,GT4	D	ko:K05802,ko:K06401,ko:K20444,ko:K22051	-	ko00000,ko01000,ko01005,ko02000	peptidase
MEDFPHPC_02132	2.12e-72	-	-	-	-	-	-	-	-
MEDFPHPC_02136	1.35e-199	-	-	-	M	-	-	-	hydrolase, family 25
MEDFPHPC_02137	1.92e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase
MEDFPHPC_02138	4.21e-20	-	-	-	S	-	-	-	KAP family P-loop domain
MEDFPHPC_02139	2.08e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
MEDFPHPC_02140	1.51e-199	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
MEDFPHPC_02141	3.61e-09	-	-	-	S	-	-	-	Acyltransferase family
MEDFPHPC_02142	3.21e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase