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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HOHILHGE_00001	3.8e-316	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HOHILHGE_00002	1.77e-261	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HOHILHGE_00003	1.45e-46	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain protein YaaA
HOHILHGE_00004	1.06e-259	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HOHILHGE_00005	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOHILHGE_00006	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HOHILHGE_00007	6.02e-64	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HOHILHGE_00008	9.82e-151	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HOHILHGE_00009	1.33e-47	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HOHILHGE_00010	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HOHILHGE_00011	2.63e-99	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOHILHGE_00012	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HOHILHGE_00013	6.24e-268	-	-	-	E	-	-	-	Major Facilitator Superfamily
HOHILHGE_00014	1.22e-78	-	-	-	-	-	-	-	-
HOHILHGE_00017	3.69e-168	yycF	-	-	K	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HOHILHGE_00018	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOHILHGE_00019	9.96e-304	yycH	-	-	S	-	-	-	YycH protein
HOHILHGE_00020	1.96e-183	yycI	-	-	S	-	-	-	YycH protein
HOHILHGE_00021	5.27e-195	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	domain protein
HOHILHGE_00022	6.12e-266	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	serine protease
HOHILHGE_00023	5.84e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HOHILHGE_00024	3.03e-94	ywnA	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_00025	1.14e-225	malR1	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOHILHGE_00026	0.0	malT	-	-	G	ko:K16211	-	ko00000,ko02000	Major Facilitator
HOHILHGE_00027	0.0	mapA	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	hydrolase, family 65, central catalytic
HOHILHGE_00028	7.69e-150	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	beta-phosphoglucomutase
HOHILHGE_00029	1.56e-136	ysdA	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	transmembrane transport
HOHILHGE_00030	4.75e-87	ysdB	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00031	1.65e-241	-	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOHILHGE_00032	6.65e-234	-	-	-	D	ko:K06889	-	ko00000	Alpha beta
HOHILHGE_00033	3.41e-232	ldhD	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_00034	2.3e-276	-	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOHILHGE_00035	7.83e-46	-	-	-	-	-	-	-	-
HOHILHGE_00036	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	associated with various cellular activities
HOHILHGE_00037	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOHILHGE_00038	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HOHILHGE_00039	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HOHILHGE_00040	2.09e-209	-	-	-	C	-	-	-	Aldo keto reductase
HOHILHGE_00041	0.0	glpQ4	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	phosphodiesterase
HOHILHGE_00042	1.05e-85	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HOHILHGE_00043	1.88e-236	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HOHILHGE_00044	2.56e-163	ybhF_2	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HOHILHGE_00045	3.7e-92	-	-	-	K	-	-	-	transcriptional regulator
HOHILHGE_00046	2.81e-212	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOHILHGE_00047	2.91e-316	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HOHILHGE_00048	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HOHILHGE_00049	2.3e-123	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HOHILHGE_00050	1.68e-168	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HOHILHGE_00051	4.18e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HOHILHGE_00052	7.17e-37	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
HOHILHGE_00053	8.98e-41	gntT	-	-	EG	-	-	-	gluconate transmembrane transporter activity
HOHILHGE_00054	5.65e-62	-	-	-	-	-	-	-	-
HOHILHGE_00055	0.0	tagE6	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HOHILHGE_00056	0.0	-	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Poly(Glycerol-phosphate) alpha-glucosyltransferase
HOHILHGE_00057	1.83e-195	metQ	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOHILHGE_00058	3.32e-242	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOHILHGE_00059	4.3e-141	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOHILHGE_00060	1.05e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HOHILHGE_00061	3.25e-311	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOHILHGE_00062	8.02e-250	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOHILHGE_00063	7.63e-155	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HOHILHGE_00064	2.66e-307	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HOHILHGE_00065	1.54e-47	dltC	6.1.1.13	-	J	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOHILHGE_00066	2.16e-304	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	MBOAT, membrane-bound O-acyltransferase family
HOHILHGE_00067	0.0	dltA	6.1.1.13	-	H	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HOHILHGE_00068	9.8e-09	dltX	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HOHILHGE_00069	3.68e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HOHILHGE_00070	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	Putative exonuclease SbcCD, C subunit
HOHILHGE_00071	1.06e-314	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HOHILHGE_00073	7.14e-280	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00074	5.36e-90	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_00075	3.07e-264	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00076	3.27e-108	-	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	UbiA prenyltransferase family
HOHILHGE_00077	1.35e-237	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOHILHGE_00078	2.53e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HOHILHGE_00079	9.36e-287	glnP	-	-	P	ko:K02029,ko:K02030,ko:K10036	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HOHILHGE_00080	1.1e-175	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00081	6.54e-309	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOHILHGE_00082	0.0	-	1.8.1.7	-	C	ko:K00383,ko:K21739	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	Pyridine nucleotide-disulfide oxidoreductase
HOHILHGE_00083	9.26e-289	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00084	8.45e-77	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_00085	5.55e-185	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00086	4.43e-272	nupG	-	-	F	ko:K03317,ko:K11535,ko:K16323	-	ko00000,ko02000	Nucleoside transporter
HOHILHGE_00087	1.89e-184	rihA	3.2.2.1	-	F	ko:K01239,ko:K01250,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	Nucleoside
HOHILHGE_00088	8.66e-172	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of a guanine in 16S rRNA
HOHILHGE_00089	9.45e-209	noc	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOHILHGE_00090	1.02e-186	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HOHILHGE_00091	4.22e-41	yyzM	-	-	S	-	-	-	Bacterial protein of unknown function (DUF951)
HOHILHGE_00092	2.13e-255	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HOHILHGE_00093	5.36e-172	-	-	-	S	-	-	-	Protein of unknown function (DUF1129)
HOHILHGE_00094	9.48e-262	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HOHILHGE_00095	1.27e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00096	1.03e-219	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOHILHGE_00097	9.6e-170	epsB	-	-	M	-	-	-	biosynthesis protein
HOHILHGE_00098	3.37e-149	ywqD	-	-	D	-	-	-	Capsular exopolysaccharide family
HOHILHGE_00099	5.4e-176	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	PHP domain protein
HOHILHGE_00100	8.42e-114	capM	-	-	M	ko:K13012	-	ko00000,ko01005	Bacterial sugar transferase
HOHILHGE_00101	3.38e-89	-	-	GT4	G	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like domain
HOHILHGE_00102	3.7e-75	-	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HOHILHGE_00103	3.5e-101	-	-	-	-	-	-	-	-
HOHILHGE_00105	3.73e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00107	3.93e-290	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00108	8.33e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
HOHILHGE_00109	3.11e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HOHILHGE_00110	1.46e-51	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00111	6.71e-31	epsJ2	-	-	S	-	-	-	Glycosyltransferase like family 2
HOHILHGE_00112	3.33e-31	-	-	-	GM	-	-	-	Glycosyltransferase like family 2
HOHILHGE_00113	4.24e-77	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HOHILHGE_00114	3.23e-154	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HOHILHGE_00115	1.01e-98	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00116	4.9e-163	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00117	4.17e-55	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HOHILHGE_00118	3.69e-195	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HOHILHGE_00119	1.31e-119	-	-	-	S	ko:K09705	-	ko00000	Cupin superfamily (DUF985)
HOHILHGE_00120	1.06e-158	vanR	-	-	K	-	-	-	response regulator
HOHILHGE_00121	2.96e-265	hpk31	-	-	T	-	-	-	Histidine kinase
HOHILHGE_00122	1.2e-262	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOHILHGE_00123	1.99e-183	-	-	-	E	-	-	-	AzlC protein
HOHILHGE_00124	2.22e-78	-	-	-	S	-	-	-	branched-chain amino acid
HOHILHGE_00125	1.09e-129	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HOHILHGE_00126	2.36e-290	cfa	2.1.1.79	-	M	ko:K00574	-	ko00000,ko01000	cyclopropane-fatty-acyl-phospholipid synthase
HOHILHGE_00127	3.05e-34	-	-	-	K	-	-	-	transcriptional regulator
HOHILHGE_00128	1.3e-12	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOHILHGE_00129	2e-223	ydbI	-	-	K	-	-	-	AI-2E family transporter
HOHILHGE_00130	0.0	fhs	6.3.4.3	-	F	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Belongs to the formate--tetrahydrofolate ligase family
HOHILHGE_00131	1.17e-105	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HOHILHGE_00132	9.71e-275	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HOHILHGE_00133	0.0	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HOHILHGE_00134	5.4e-219	hrpQ	4.6.1.1	-	T	ko:K01768,ko:K03220,ko:K10914	ko00230,ko02020,ko02024,ko02025,ko02026,ko04113,ko04213,ko05111,map00230,map02020,map02024,map02025,map02026,map04113,map04213,map05111	ko00000,ko00001,ko00002,ko01000,ko02044,ko03000	histone H2A K63-linked ubiquitination
HOHILHGE_00135	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HOHILHGE_00136	4.36e-14	nagZ	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Glycosyl hydrolase family 3 N terminal domain
HOHILHGE_00137	5.04e-173	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HOHILHGE_00138	1.36e-50	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOHILHGE_00139	4.87e-164	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOHILHGE_00140	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HOHILHGE_00141	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HOHILHGE_00142	4.8e-251	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HOHILHGE_00143	8.9e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HOHILHGE_00144	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HOHILHGE_00145	4.56e-306	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HOHILHGE_00146	1.15e-169	gpmA	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOHILHGE_00147	1.35e-283	araT	2.6.1.57	-	E	ko:K00832,ko:K00841	ko00270,ko00300,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01230,map00270,map00300,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOHILHGE_00148	5.81e-226	-	-	-	-	-	-	-	-
HOHILHGE_00149	1.52e-67	-	-	-	S	-	-	-	Cupredoxin-like domain
HOHILHGE_00150	1.55e-66	-	-	-	S	-	-	-	Cupredoxin-like domain
HOHILHGE_00151	0.0	copA	3.6.3.3, 3.6.3.5, 3.6.3.54	-	P	ko:K01534,ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HOHILHGE_00152	1.41e-34	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_00153	6.79e-59	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
HOHILHGE_00154	3.06e-43	yejD	2.4.2.6	-	F	ko:K08728	ko00240,map00240	ko00000,ko00001,ko01000	nucleoside 2-deoxyribosyltransferase
HOHILHGE_00155	8.34e-101	-	-	-	-	-	-	-	-
HOHILHGE_00157	4.26e-112	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00158	1.59e-54	yodA	-	-	S	-	-	-	Tautomerase enzyme
HOHILHGE_00159	1.09e-05	crp2	-	-	K	ko:K10914,ko:K21562	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	ko00000,ko00001,ko03000	helix_turn_helix, cAMP Regulatory protein
HOHILHGE_00160	7.18e-153	pnb	-	-	C	-	-	-	nitroreductase
HOHILHGE_00161	3.31e-106	-	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha/beta hydrolase family
HOHILHGE_00163	1.25e-10	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HOHILHGE_00164	4.56e-06	-	-	-	K	-	-	-	LysR substrate binding domain
HOHILHGE_00165	4.54e-60	-	-	-	C	-	-	-	Aldo keto reductase
HOHILHGE_00166	1.46e-05	-	-	-	S	-	-	-	CsbD-like
HOHILHGE_00168	7.43e-08	-	-	-	C	-	-	-	Aldo/keto reductase family
HOHILHGE_00169	1.65e-107	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_00170	4.04e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00171	3.35e-115	-	-	-	P	-	-	-	Cadmium resistance transporter
HOHILHGE_00172	8.68e-44	ydzE	-	-	EG	-	-	-	spore germination
HOHILHGE_00173	6.04e-71	-	4.1.1.44	-	O	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HOHILHGE_00174	1.04e-199	isdF	-	-	U	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HOHILHGE_00175	3.01e-179	-	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00176	3.73e-300	proP	-	-	EGP	ko:K03761,ko:K03762	-	ko00000,ko02000	Sugar (and other) transporter
HOHILHGE_00177	1.64e-202	xth	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HOHILHGE_00178	8.34e-101	-	-	-	-	-	-	-	-
HOHILHGE_00179	9.4e-231	-	1.1.1.26	-	CH	ko:K00015	ko00630,ko01100,ko01110,ko01120,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_00180	1.24e-24	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class-V
HOHILHGE_00181	3.04e-238	fdrA	-	-	C	ko:K02381	-	ko00000	CoA-ligase
HOHILHGE_00182	2.51e-184	rihA	-	-	F	ko:K01250	-	ko00000,ko01000	Inosine-uridine preferring nucleoside hydrolase
HOHILHGE_00183	1.58e-159	-	-	-	C	-	-	-	nitroreductase
HOHILHGE_00184	6.62e-175	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOHILHGE_00185	4.33e-70	-	-	-	S	-	-	-	Mazg nucleotide pyrophosphohydrolase
HOHILHGE_00186	1.12e-224	adh1	1.1.1.1	-	E	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HOHILHGE_00187	0.0	pepN	3.4.11.2	-	E	ko:K01256	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	aminopeptidase
HOHILHGE_00188	8.25e-46	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Oxidoreductase, aldo keto reductase family protein
HOHILHGE_00189	1.42e-152	akr5f	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	reductase
HOHILHGE_00190	3.41e-88	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_00191	4.27e-110	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_00193	1.75e-180	nfrA	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	nitroreductase
HOHILHGE_00195	1.1e-197	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOHILHGE_00196	1.5e-257	napA	-	-	P	-	-	-	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HOHILHGE_00197	0.0	-	-	-	L	-	-	-	DNA helicase
HOHILHGE_00198	3.78e-220	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HOHILHGE_00199	2.36e-287	mvaA	1.1.1.88, 2.3.1.9	-	C	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the HMG-CoA reductase family
HOHILHGE_00200	7.53e-239	-	-	-	-	-	-	-	-
HOHILHGE_00201	1.56e-163	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	SIR2 family
HOHILHGE_00202	1.32e-269	blt	-	-	EGP	ko:K08153	-	ko00000,ko00002,ko02000	transporter
HOHILHGE_00203	1.59e-205	yunF	-	-	F	-	-	-	Protein of unknown function DUF72
HOHILHGE_00204	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HOHILHGE_00205	1.5e-185	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD family
HOHILHGE_00206	3.77e-127	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HOHILHGE_00207	8.42e-204	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HOHILHGE_00208	4.72e-204	ispE	2.7.1.148	-	F	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HOHILHGE_00209	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00210	3.47e-213	psaA	-	-	P	ko:K02077,ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HOHILHGE_00211	5.45e-121	adcC	-	-	P	ko:K02074,ko:K09817,ko:K11710	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HOHILHGE_00212	2.81e-166	-	-	-	U	ko:K02075	-	ko00000,ko00002,ko02000	ABC 3 transport family
HOHILHGE_00213	4.31e-193	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HOHILHGE_00214	2.72e-299	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HOHILHGE_00215	1.27e-226	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOHILHGE_00216	6.2e-77	-	-	-	-	-	-	-	-
HOHILHGE_00217	9.64e-183	yidA	-	-	S	-	-	-	hydrolase
HOHILHGE_00218	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	HD domain protein
HOHILHGE_00219	5.23e-97	ywiB	-	-	S	-	-	-	Domain of unknown function (DUF1934)
HOHILHGE_00220	8.05e-95	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HOHILHGE_00221	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HOHILHGE_00222	4.36e-302	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HOHILHGE_00223	3.85e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HOHILHGE_00224	1.69e-37	-	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HOHILHGE_00225	5.38e-158	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	sortase family
HOHILHGE_00226	6.07e-60	ptpA	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HOHILHGE_00227	1.66e-119	lemA	-	-	S	ko:K03744	-	ko00000	LemA family
HOHILHGE_00228	1.34e-202	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HOHILHGE_00229	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HOHILHGE_00230	0.0	cshA	3.6.4.13	-	F	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HOHILHGE_00231	1.18e-78	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HOHILHGE_00232	4.04e-264	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HOHILHGE_00233	5.83e-74	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HOHILHGE_00234	3.71e-147	-	-	-	S	-	-	-	(CBS) domain
HOHILHGE_00235	1.13e-131	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HOHILHGE_00236	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HOHILHGE_00237	2.47e-53	yabO	-	-	J	-	-	-	S4 domain protein
HOHILHGE_00238	5.88e-74	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HOHILHGE_00239	6.71e-113	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding
HOHILHGE_00240	0.0	tilS	2.4.2.8, 6.3.4.19	-	J	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HOHILHGE_00241	3.52e-124	hpt	2.4.2.8	-	F	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the purine pyrimidine phosphoribosyltransferase family
HOHILHGE_00242	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HOHILHGE_00243	3.89e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HOHILHGE_00244	2.64e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HOHILHGE_00245	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HOHILHGE_00248	8.34e-101	-	-	-	-	-	-	-	-
HOHILHGE_00251	1.14e-72	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOHILHGE_00252	3.65e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00253	3.36e-62	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HOHILHGE_00254	6.64e-41	-	-	-	P	ko:K06901	-	ko00000,ko02000	secondary active sulfate transmembrane transporter activity
HOHILHGE_00255	1.13e-87	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HOHILHGE_00256	5.26e-76	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOHILHGE_00257	2.63e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00258	1.02e-295	gdhA	1.4.1.4	-	E	ko:K00262	ko00220,ko00250,ko00910,ko01100,map00220,map00250,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HOHILHGE_00259	0.0	nox	1.6.3.4	-	C	ko:K17869	-	ko00000,ko01000	NADH oxidase
HOHILHGE_00260	0.0	npr	1.11.1.1	-	C	ko:K05910	-	ko00000,ko01000	NADH oxidase
HOHILHGE_00261	1.06e-190	-	-	-	S	-	-	-	hydrolase
HOHILHGE_00262	2.27e-289	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00263	2.23e-139	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00264	3.23e-225	-	-	-	D	-	-	-	nuclear chromosome segregation
HOHILHGE_00265	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HOHILHGE_00266	2.08e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00267	6.34e-314	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00268	4.19e-23	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOHILHGE_00269	6.02e-269	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00270	1.65e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOHILHGE_00273	2.49e-144	-	-	-	-	-	-	-	-
HOHILHGE_00274	7.44e-169	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HOHILHGE_00275	8.7e-166	yvoA_2	-	-	K	ko:K03710	-	ko00000,ko03000	UbiC transcription regulator-associated domain protein
HOHILHGE_00276	0.0	pncB	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOHILHGE_00277	5.46e-195	nadE	6.3.1.5	-	F	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HOHILHGE_00278	0.0	tex	-	-	K	ko:K06959	-	ko00000	Tex-like protein N-terminal domain protein
HOHILHGE_00279	2e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HOHILHGE_00281	4.47e-314	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00282	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 2 family
HOHILHGE_00283	3.2e-241	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HOHILHGE_00284	1.25e-212	-	-	-	S	ko:K07088	-	ko00000	Sodium Bile acid symporter family
HOHILHGE_00285	3.86e-165	gpmA1	5.4.2.11	-	G	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HOHILHGE_00286	2.09e-211	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOHILHGE_00287	0.0	pepC	3.4.22.40	-	E	ko:K01372	-	ko00000,ko01000,ko01002	Peptidase C1-like family
HOHILHGE_00288	6.31e-55	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HOHILHGE_00289	2.02e-41	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	transferase hexapeptide repeat
HOHILHGE_00290	6.11e-159	-	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOHILHGE_00291	7.63e-72	HA62_12640	-	-	S	ko:K06975	-	ko00000	GCN5-related N-acetyl-transferase
HOHILHGE_00292	3.82e-122	dut	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	dUTP diphosphatase
HOHILHGE_00293	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HOHILHGE_00294	1.58e-263	yacL	-	-	S	-	-	-	domain protein
HOHILHGE_00295	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HOHILHGE_00296	7.92e-129	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HOHILHGE_00297	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HOHILHGE_00298	5.09e-93	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HOHILHGE_00299	6.81e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOHILHGE_00300	7.6e-133	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HOHILHGE_00301	6.86e-28	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOHILHGE_00302	2.48e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HOHILHGE_00303	1.18e-126	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HOHILHGE_00304	3.34e-68	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HOHILHGE_00305	1.96e-156	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HOHILHGE_00306	1.47e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00307	2.05e-166	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_00308	4.29e-310	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HOHILHGE_00309	3.88e-107	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HOHILHGE_00310	8.24e-71	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HOHILHGE_00311	1.21e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00312	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	ubiquinol oxidase
HOHILHGE_00313	4.87e-236	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase subunit II
HOHILHGE_00314	0.0	cydC	-	-	CO	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HOHILHGE_00315	0.0	cydD	-	-	CO	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HOHILHGE_00316	0.0	adhE	1.1.1.1, 1.2.1.10	-	C	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	belongs to the iron- containing alcohol dehydrogenase family
HOHILHGE_00317	0.0	brnQ	-	-	U	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HOHILHGE_00318	1.04e-248	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOHILHGE_00319	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOHILHGE_00320	6.56e-48	nrdH	-	-	O	ko:K06191	-	ko00000	Glutaredoxin
HOHILHGE_00321	3.69e-113	tadA	3.5.4.33	-	F	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HOHILHGE_00323	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOHILHGE_00324	3.97e-60	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HOHILHGE_00325	6.48e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HOHILHGE_00326	2.06e-28	-	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HOHILHGE_00327	2.81e-148	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HOHILHGE_00328	3.74e-69	yaaQ	-	-	S	-	-	-	Cyclic-di-AMP receptor
HOHILHGE_00329	6.77e-247	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HOHILHGE_00330	2.47e-74	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HOHILHGE_00331	9.46e-201	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HOHILHGE_00332	1.91e-187	fat	3.1.2.21	-	I	ko:K01071	ko00061,ko01100,map00061,map01100	ko00000,ko00001,ko01000,ko01004	Acyl-ACP thioesterase
HOHILHGE_00333	0.0	ppx3	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HOHILHGE_00334	0.0	ppk	2.7.4.1	-	P	ko:K00937	ko00190,ko03018,map00190,map03018	ko00000,ko00001,ko01000,ko03019	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HOHILHGE_00335	9.23e-219	ppx	3.6.1.11, 3.6.1.40	-	FP	ko:K01524	ko00230,map00230	ko00000,ko00001,ko01000	exopolyphosphatase
HOHILHGE_00336	2.86e-245	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HOHILHGE_00337	2.06e-198	-	-	-	KT	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	YcbB domain
HOHILHGE_00338	2.08e-239	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HOHILHGE_00339	8.23e-218	arcC	2.7.2.2	-	E	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	ko00000,ko00001,ko01000	Belongs to the carbamate kinase family
HOHILHGE_00340	1.91e-302	arcA	3.5.3.6	-	E	ko:K01478	ko00220,ko01100,ko01110,ko01130,map00220,map01100,map01110,map01130	ko00000,ko00001,ko01000	Arginine
HOHILHGE_00341	0.0	arcD	-	-	E	ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HOHILHGE_00342	1.74e-274	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HOHILHGE_00343	2.67e-273	arcT	-	-	E	-	-	-	Aminotransferase
HOHILHGE_00344	1.32e-165	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	Universal bacterial protein YeaZ
HOHILHGE_00345	5.33e-141	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	Ribosomal-protein-alanine acetyltransferase
HOHILHGE_00346	1.17e-246	tsaD	2.3.1.234	-	J	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HOHILHGE_00348	3.83e-100	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOHILHGE_00349	6.02e-94	-	-	-	K	-	-	-	Transcriptional regulator, MarR family
HOHILHGE_00350	2.43e-215	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HOHILHGE_00351	1.7e-45	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOHILHGE_00352	2.64e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	Malonyl CoA-acyl carrier protein transacylase
HOHILHGE_00353	8.92e-164	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HOHILHGE_00354	7.65e-291	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HOHILHGE_00355	3.46e-94	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOHILHGE_00356	1.13e-97	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HOHILHGE_00357	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HOHILHGE_00358	2.25e-206	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HOHILHGE_00359	5.43e-181	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	alpha subunit
HOHILHGE_00360	1.55e-174	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HOHILHGE_00361	1.67e-117	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HOHILHGE_00362	7.03e-223	birA	6.3.4.15	-	H	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HOHILHGE_00363	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter, ATP-binding protein
HOHILHGE_00364	8.05e-149	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HOHILHGE_00365	5.71e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HOHILHGE_00366	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HOHILHGE_00367	0.0	ydaO	-	-	E	-	-	-	amino acid
HOHILHGE_00368	4.12e-50	-	-	-	-	-	-	-	-
HOHILHGE_00369	4e-147	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	YigZ family
HOHILHGE_00370	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	Helicase C-terminal domain protein
HOHILHGE_00371	8.42e-164	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Competence protein
HOHILHGE_00372	4.64e-124	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HOHILHGE_00373	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HOHILHGE_00374	1.45e-257	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HOHILHGE_00375	1.97e-70	-	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain protein
HOHILHGE_00376	4.15e-69	yvlD	-	-	S	ko:K08972	-	ko00000	Mycobacterial 4 TMS phage holin, superfamily IV
HOHILHGE_00377	2.39e-227	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HOHILHGE_00378	4.38e-208	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HOHILHGE_00379	6.13e-234	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HOHILHGE_00380	7.64e-220	galU	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HOHILHGE_00381	1.51e-188	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Carbon-nitrogen hydrolase
HOHILHGE_00382	1.21e-286	mtnE	-	-	E	ko:K08969	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOHILHGE_00383	6.21e-241	ykpB	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HOHILHGE_00384	2.15e-99	yphH	-	-	S	-	-	-	Cupin domain
HOHILHGE_00385	7.29e-166	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HOHILHGE_00386	3.3e-198	metA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HOHILHGE_00387	1.04e-215	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HOHILHGE_00388	3.96e-253	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HOHILHGE_00389	1.08e-215	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HOHILHGE_00390	2.38e-168	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOHILHGE_00391	0.0	pgm	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HOHILHGE_00392	1.19e-143	yfbR	-	-	S	ko:K07023	-	ko00000	HD containing hydrolase-like enzyme
HOHILHGE_00394	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HOHILHGE_00395	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HOHILHGE_00396	8.41e-260	-	-	-	-	-	-	-	-
HOHILHGE_00397	1.45e-201	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HOHILHGE_00398	1.84e-236	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HOHILHGE_00399	1.58e-212	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HOHILHGE_00400	4.18e-155	-	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HOHILHGE_00401	2.96e-132	clpP	3.4.21.92	-	O	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HOHILHGE_00409	2.66e-119	-	-	-	S	ko:K06919	-	ko00000	D5 N terminal like
HOHILHGE_00410	4.68e-195	-	-	-	L	-	-	-	DNA replication protein
HOHILHGE_00413	1.4e-10	-	-	-	S	-	-	-	Helix-turn-helix domain
HOHILHGE_00414	1.87e-112	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOHILHGE_00415	7.63e-250	int2	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HOHILHGE_00416	1.71e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00417	3.82e-23	-	-	-	-	-	-	-	-
HOHILHGE_00418	1.31e-244	gap	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HOHILHGE_00419	1.21e-286	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HOHILHGE_00420	2.92e-184	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOHILHGE_00422	0.0	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HOHILHGE_00423	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HOHILHGE_00424	0.0	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOHILHGE_00425	6.82e-46	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HOHILHGE_00426	0.0	rnr	-	-	J	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HOHILHGE_00427	4.66e-110	smpB	-	-	J	ko:K03664	-	ko00000	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HOHILHGE_00428	2.36e-139	-	-	-	-	-	-	-	-
HOHILHGE_00429	2.52e-172	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HOHILHGE_00430	9.74e-229	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	phosphate acetyltransferase
HOHILHGE_00431	4.21e-105	ydiB	-	-	O	ko:K06925	-	ko00000,ko03016	Hydrolase, P-loop family
HOHILHGE_00432	5.51e-118	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOHILHGE_00433	4e-133	dnaQ	2.7.7.7	-	L	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HOHILHGE_00434	2.34e-212	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation
HOHILHGE_00435	3.25e-192	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HOHILHGE_00436	1.19e-151	ybbR	-	-	S	-	-	-	YbbR-like protein
HOHILHGE_00437	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HOHILHGE_00438	7.85e-227	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00439	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HOHILHGE_00440	2.55e-68	-	-	-	-	-	-	-	-
HOHILHGE_00441	1.17e-262	oatA	-	-	I	-	-	-	Acyltransferase
HOHILHGE_00442	3.53e-192	XK27_02985	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOHILHGE_00443	1.15e-106	lytE	-	-	M	-	-	-	Lysin motif
HOHILHGE_00444	6.96e-222	-	-	-	S	-	-	-	Conserved hypothetical protein 698
HOHILHGE_00445	9.98e-215	-	-	-	K	-	-	-	LysR substrate binding domain
HOHILHGE_00446	1.8e-165	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HOHILHGE_00447	1.28e-190	yitS	-	-	S	-	-	-	EDD domain protein, DegV family
HOHILHGE_00448	2.94e-115	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HOHILHGE_00449	1.5e-231	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Peroxidase
HOHILHGE_00450	2.22e-231	manL	2.7.1.191, 2.7.1.202	-	G	ko:K02769,ko:K02793,ko:K02794	ko00051,ko00520,ko01100,ko01120,ko02060,map00051,map00520,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system sorbose subfamily IIB component
HOHILHGE_00451	2.38e-164	manY	-	-	G	ko:K02746,ko:K02795	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system
HOHILHGE_00452	1.37e-219	manN	-	-	G	ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	system, mannose fructose sorbose family IID component
HOHILHGE_00453	1.04e-75	manO	-	-	S	-	-	-	Domain of unknown function (DUF956)
HOHILHGE_00454	3.45e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00456	2.53e-125	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_00457	6.86e-18	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_00458	2.91e-168	yclJ	-	-	K	ko:K02483	-	ko00000,ko02022	response regulator
HOHILHGE_00459	0.0	yclK	-	-	T	-	-	-	Histidine kinase
HOHILHGE_00460	2.05e-195	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HOHILHGE_00461	5.83e-310	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00462	1.88e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Peroxiredoxin
HOHILHGE_00463	0.0	-	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Thioredoxin domain
HOHILHGE_00464	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HOHILHGE_00466	5.84e-110	-	-	-	K	-	-	-	GNAT family
HOHILHGE_00467	1.94e-153	XK27_08875	-	-	O	-	-	-	PFAM peptidase M10A and M12B, matrixin and adamalysin
HOHILHGE_00468	3.74e-205	yvgN	-	-	S	-	-	-	Aldo keto reductase
HOHILHGE_00469	6.37e-185	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HOHILHGE_00470	1.5e-167	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Belongs to the alpha-acetolactate decarboxylase family
HOHILHGE_00472	2.67e-75	-	-	-	-	-	-	-	-
HOHILHGE_00474	5.8e-14	-	-	-	-	-	-	-	-
HOHILHGE_00475	4.17e-102	-	-	-	K	-	-	-	Winged helix-turn-helix DNA-binding
HOHILHGE_00476	0.0	ycfI	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00477	6.77e-54	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOHILHGE_00478	1.1e-172	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOHILHGE_00479	4.21e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_00480	9.81e-194	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00481	9.52e-143	yfiC	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HOHILHGE_00482	3.76e-245	ampC	-	-	V	-	-	-	Beta-lactamase
HOHILHGE_00483	0.0	cls	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOHILHGE_00484	2.31e-63	-	-	-	-	-	-	-	-
HOHILHGE_00485	2.15e-180	-	-	-	S	ko:K07009	-	ko00000	CobB/CobQ-like glutamine amidotransferase domain
HOHILHGE_00486	0.0	murE2	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Domain of unknown function (DUF1727)
HOHILHGE_00487	1.78e-139	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HOHILHGE_00488	1.53e-207	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HOHILHGE_00489	9.13e-202	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HOHILHGE_00490	1.32e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HOHILHGE_00491	4.46e-294	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HOHILHGE_00492	3.86e-149	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HOHILHGE_00493	1.35e-250	yibE	-	-	S	-	-	-	overlaps another CDS with the same product name
HOHILHGE_00494	7.81e-165	yibF	-	-	S	-	-	-	overlaps another CDS with the same product name
HOHILHGE_00495	1.28e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Permease
HOHILHGE_00496	4.65e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HOHILHGE_00497	2.13e-27	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOHILHGE_00498	4.35e-77	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HOHILHGE_00499	3.51e-119	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HOHILHGE_00500	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HOHILHGE_00501	1.78e-213	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HOHILHGE_00502	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HOHILHGE_00503	1.19e-88	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HOHILHGE_00504	8.07e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF1146)
HOHILHGE_00505	1.97e-277	-	-	-	M	-	-	-	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)
HOHILHGE_00506	9.42e-234	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Cell shape determining protein MreB Mrl
HOHILHGE_00507	7.67e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2969)
HOHILHGE_00508	5.09e-283	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HOHILHGE_00510	1.9e-231	-	-	-	S	-	-	-	Protein of unknown function (DUF2785)
HOHILHGE_00511	5.85e-275	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HOHILHGE_00512	1.99e-194	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HOHILHGE_00513	6.08e-107	uspA	-	-	T	-	-	-	universal stress protein
HOHILHGE_00515	6.16e-299	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HOHILHGE_00516	2.31e-110	XK27_05190	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HOHILHGE_00517	1.52e-98	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase
HOHILHGE_00518	6.31e-171	-	-	-	S	-	-	-	Membrane
HOHILHGE_00519	1.17e-187	-	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HOHILHGE_00520	8.61e-35	-	-	-	S	-	-	-	YjcQ protein
HOHILHGE_00523	5.1e-140	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HOHILHGE_00524	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HOHILHGE_00525	3.37e-272	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HOHILHGE_00526	1.18e-291	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HOHILHGE_00527	8.87e-275	yojA	-	-	EG	ko:K03299	-	ko00000,ko02000	GntP family permease
HOHILHGE_00528	6.39e-260	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HOHILHGE_00529	1.3e-47	-	-	-	M	-	-	-	LysM domain
HOHILHGE_00530	1.19e-50	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HOHILHGE_00531	4.31e-194	is18	-	-	L	-	-	-	Integrase core domain
HOHILHGE_00532	2.2e-315	sufI	-	-	Q	-	-	-	Multicopper oxidase
HOHILHGE_00533	5.09e-61	sufI	-	-	Q	-	-	-	Multicopper oxidase
HOHILHGE_00534	1.26e-34	-	-	-	-	-	-	-	-
HOHILHGE_00535	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00536	1.89e-101	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00537	4.15e-176	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00538	2.53e-242	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00539	4.04e-67	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HOHILHGE_00540	5.61e-66	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HOHILHGE_00541	5.68e-283	citP	-	-	C	-	-	-	Na citrate symporter
HOHILHGE_00542	2.81e-259	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HOHILHGE_00543	4.86e-14	citR	-	-	K	-	-	-	Transcriptional regulator, contains sigma factor-related N-terminal domain
HOHILHGE_00544	1.2e-210	-	-	-	L	ko:K07482	-	ko00000	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00545	3.83e-53	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HOHILHGE_00546	9.6e-32	pinR1	-	-	L	-	-	-	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HOHILHGE_00548	3.11e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HOHILHGE_00549	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HOHILHGE_00550	1.89e-316	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HOHILHGE_00551	5.3e-150	radC	-	-	L	ko:K03630	-	ko00000	DNA repair protein
HOHILHGE_00552	4.47e-231	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	cell shape determining protein MreB
HOHILHGE_00553	2.27e-186	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HOHILHGE_00554	9.04e-120	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	rod shape-determining protein MreD
HOHILHGE_00555	3.81e-142	yecS_2	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HOHILHGE_00556	6.63e-147	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00557	3.88e-204	aatB	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HOHILHGE_00558	4.68e-298	ymfF	-	-	S	-	-	-	Peptidase M16 inactive domain protein
HOHILHGE_00559	0.0	ymfH	-	-	S	-	-	-	Peptidase M16
HOHILHGE_00560	2.15e-146	-	-	-	S	-	-	-	Helix-turn-helix domain
HOHILHGE_00561	9.93e-130	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HOHILHGE_00562	3.8e-292	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HOHILHGE_00563	7.88e-245	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HOHILHGE_00564	2.27e-305	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HOHILHGE_00565	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HOHILHGE_00566	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HOHILHGE_00567	1.77e-135	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HOHILHGE_00568	3.61e-243	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HOHILHGE_00569	1.79e-225	-	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	queuine tRNA-ribosyltransferase activity
HOHILHGE_00570	1.11e-68	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase
HOHILHGE_00571	2.8e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	DHHA1 domain protein
HOHILHGE_00572	4.66e-298	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HOHILHGE_00573	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HOHILHGE_00574	1.06e-57	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HOHILHGE_00575	4.97e-97	yrrK	-	-	J	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HOHILHGE_00576	3.84e-53	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HOHILHGE_00577	3.2e-211	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOHILHGE_00578	2.23e-119	cvpA	-	-	S	-	-	-	Colicin V production protein
HOHILHGE_00579	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HOHILHGE_00580	3.92e-70	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOHILHGE_00581	6.22e-285	-	-	-	P	-	-	-	Chloride transporter, ClC family
HOHILHGE_00582	2.56e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00583	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_00584	8.44e-195	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00585	1.96e-120	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HOHILHGE_00586	3.69e-189	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HOHILHGE_00587	6.24e-139	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HOHILHGE_00588	2.25e-121	-	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HOHILHGE_00589	8.33e-192	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOHILHGE_00590	1.06e-200	ykuT	-	-	M	ko:K16052,ko:K22044	-	ko00000,ko02000	mechanosensitive ion channel
HOHILHGE_00591	5.14e-68	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HOHILHGE_00592	4.62e-92	-	-	-	-	-	-	-	-
HOHILHGE_00593	1.8e-271	pepQ	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HOHILHGE_00594	3.29e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HOHILHGE_00595	5.46e-179	-	-	-	-	-	-	-	-
HOHILHGE_00596	5.01e-172	yebC	-	-	K	-	-	-	Transcriptional regulatory protein
HOHILHGE_00597	2.74e-111	-	-	-	M	-	-	-	PFAM NLP P60 protein
HOHILHGE_00598	6.94e-149	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HOHILHGE_00599	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HOHILHGE_00600	1.72e-212	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00601	2.07e-133	ykcB	-	-	M	-	-	-	Dolichyl-phosphate-mannose-protein mannosyltransferase
HOHILHGE_00602	1.28e-226	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	Type II IV secretion system protein
HOHILHGE_00603	4.8e-209	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	type II secretion system
HOHILHGE_00604	8.88e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	competence protein ComGC
HOHILHGE_00609	6.17e-203	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	N-6 DNA Methylase
HOHILHGE_00610	7.86e-286	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HOHILHGE_00611	2.53e-242	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00612	7.82e-147	-	-	-	S	-	-	-	Calcineurin-like phosphoesterase
HOHILHGE_00613	9.43e-127	yutD	-	-	S	-	-	-	Protein of unknown function (DUF1027)
HOHILHGE_00614	4.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HOHILHGE_00615	2.65e-21	-	-	-	S	-	-	-	Protein of unknown function (DUF1461)
HOHILHGE_00616	8.3e-142	dedA	-	-	S	ko:K03975	-	ko00000	SNARE-like domain protein
HOHILHGE_00617	8.34e-101	-	-	-	-	-	-	-	-
HOHILHGE_00638	1.12e-90	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HOHILHGE_00639	7.24e-151	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HOHILHGE_00640	2.41e-262	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HOHILHGE_00641	1.03e-147	yjbH	-	-	Q	-	-	-	Thioredoxin
HOHILHGE_00642	3.03e-158	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	RelA SpoT domain protein
HOHILHGE_00643	5.27e-194	nadK	2.7.1.23	-	F	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HOHILHGE_00644	4.25e-218	yjbO	5.4.99.23	-	G	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOHILHGE_00645	4.25e-248	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HOHILHGE_00646	2.63e-206	rrmA	2.1.1.187	-	H	ko:K00563,ko:K10947	-	ko00000,ko01000,ko03000,ko03009	Methyltransferase
HOHILHGE_00647	8.44e-109	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00648	9.5e-21	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HOHILHGE_00649	6.74e-122	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HOHILHGE_00650	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HOHILHGE_00651	4.5e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF4044)
HOHILHGE_00652	6.91e-76	-	-	-	-	-	-	-	-
HOHILHGE_00653	4.43e-103	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HOHILHGE_00654	5.37e-221	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HOHILHGE_00655	4.29e-30	ftsL	-	-	D	-	-	-	Cell division protein FtsL
HOHILHGE_00656	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOHILHGE_00657	1.82e-226	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HOHILHGE_00658	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HOHILHGE_00659	2.06e-259	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HOHILHGE_00660	1.49e-190	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HOHILHGE_00661	4.88e-300	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HOHILHGE_00662	9.01e-294	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HOHILHGE_00663	1.5e-101	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HOHILHGE_00664	7.27e-56	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	YGGT family
HOHILHGE_00665	1.75e-186	ylmH	-	-	S	-	-	-	S4 domain protein
HOHILHGE_00666	6.19e-143	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	DivIVA domain protein
HOHILHGE_00668	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HOHILHGE_00669	2.83e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HOHILHGE_00670	1.28e-126	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HOHILHGE_00671	9.41e-09	-	-	-	-	-	-	-	-
HOHILHGE_00672	3.26e-162	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HOHILHGE_00673	6.47e-76	XK27_04120	-	-	S	-	-	-	Putative amino acid metabolism
HOHILHGE_00674	4.17e-284	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HOHILHGE_00675	0.0	-	-	-	S	-	-	-	amidohydrolase
HOHILHGE_00676	3.1e-218	hdhL	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HOHILHGE_00677	1.11e-156	pgm6	-	-	G	-	-	-	phosphoglycerate mutase
HOHILHGE_00678	2.69e-158	-	-	-	S	-	-	-	repeat protein
HOHILHGE_00679	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HOHILHGE_00680	6.32e-227	prs2	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HOHILHGE_00681	1.49e-97	-	-	-	L	-	-	-	Transposase DDE domain
HOHILHGE_00682	7.87e-88	-	-	-	L	-	-	-	Putative transposase of IS4/5 family (DUF4096)
HOHILHGE_00683	1.14e-96	-	-	-	P	-	-	-	ArsC family
HOHILHGE_00684	1.99e-237	-	-	-	I	-	-	-	Diacylglycerol kinase catalytic
HOHILHGE_00685	8.83e-43	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HOHILHGE_00686	6.12e-98	-	-	-	-	-	-	-	-
HOHILHGE_00687	3.5e-132	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HOHILHGE_00688	3.66e-64	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HOHILHGE_00689	1.96e-177	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the inositol monophosphatase superfamily
HOHILHGE_00690	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HOHILHGE_00691	4.63e-274	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HOHILHGE_00692	1.31e-63	ylbG	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2129)
HOHILHGE_00693	1.27e-128	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	RNA methyltransferase, RsmD family
HOHILHGE_00694	8.39e-114	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HOHILHGE_00695	5.62e-252	lon	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HOHILHGE_00696	4.22e-127	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	Competence protein ComEA
HOHILHGE_00697	8.66e-116	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HOHILHGE_00698	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HOHILHGE_00699	6.65e-236	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HOHILHGE_00700	4.12e-47	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HOHILHGE_00701	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HOHILHGE_00702	4.24e-19	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HOHILHGE_00703	2.48e-146	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HOHILHGE_00704	6.85e-71	gshAB	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HOHILHGE_00705	0.0	rnjB	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOHILHGE_00706	5.46e-207	-	-	-	S	-	-	-	Tetratricopeptide repeat
HOHILHGE_00707	1.42e-287	tuf	-	-	J	ko:K02358,ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HOHILHGE_00708	1.91e-298	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HOHILHGE_00709	2.06e-297	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HOHILHGE_00710	2.97e-137	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HOHILHGE_00711	5.48e-70	-	-	-	S	-	-	-	mazG nucleotide pyrophosphohydrolase
HOHILHGE_00713	3.97e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00714	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HOHILHGE_00715	9.56e-317	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOHILHGE_00716	2.38e-222	rnz	3.1.26.11	-	J	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HOHILHGE_00717	4.34e-198	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HOHILHGE_00718	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HOHILHGE_00719	2.41e-123	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HOHILHGE_00720	5.5e-80	-	-	-	S	-	-	-	Domain of unknown function (DUF4440)
HOHILHGE_00721	5.43e-195	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_00722	1.11e-27	ldhA	1.1.1.28	-	C	ko:K03778,ko:K18347	ko00620,ko01120,ko01502,ko02020,map00620,map01120,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01504	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_00723	1.6e-165	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_00724	9.5e-21	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HOHILHGE_00725	8.44e-109	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00726	2.72e-138	mhpD	-	-	Q	ko:K02509	ko00350,ko01120,map00350,map01120	ko00000,ko00001,ko01000	hydratase
HOHILHGE_00727	3.54e-57	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HOHILHGE_00728	1.34e-126	ydeQ	-	-	S	ko:K11748	-	ko00000,ko02000	Flavodoxin-like fold
HOHILHGE_00729	5.66e-57	-	-	-	S	-	-	-	Protein conserved in bacteria
HOHILHGE_00730	1.23e-73	-	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HOHILHGE_00731	1.56e-67	-	-	-	S	-	-	-	Sugar efflux transporter for intercellular exchange
HOHILHGE_00732	5.56e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_00733	5.94e-211	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00734	2.61e-242	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_00736	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Aluminium induced protein
HOHILHGE_00737	1.42e-20	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HOHILHGE_00739	3.84e-233	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOHILHGE_00740	9.97e-103	-	-	-	F	-	-	-	Nucleoside 2-deoxyribosyltransferase
HOHILHGE_00741	3.55e-123	-	-	-	-	-	-	-	-
HOHILHGE_00743	7.54e-13	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_00744	4.4e-259	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_00745	3.99e-155	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_00746	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HOHILHGE_00747	0.0	frdA	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOHILHGE_00748	6.6e-58	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOHILHGE_00749	1.13e-114	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOHILHGE_00750	7.82e-315	citP	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HOHILHGE_00751	1.49e-223	citR	-	-	K	-	-	-	sugar-binding domain protein
HOHILHGE_00752	2.08e-140	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HOHILHGE_00753	3.73e-103	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00754	2.92e-106	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00755	6e-267	mae	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme, NAD binding domain
HOHILHGE_00756	1.32e-249	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HOHILHGE_00757	3.36e-61	citD	-	-	C	ko:K01646	ko02020,map02020	ko00000,ko00001	Covalent carrier of the coenzyme of citrate lyase
HOHILHGE_00758	1.77e-208	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HOHILHGE_00759	0.0	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HOHILHGE_00760	0.0	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HOHILHGE_00761	1.06e-185	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HOHILHGE_00762	1.45e-35	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00763	7.6e-288	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00764	0.0	uvrA2	-	-	L	-	-	-	ABC transporter
HOHILHGE_00765	2.29e-273	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00766	3.13e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HOHILHGE_00767	2.91e-70	sdhB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	Serine dehydratase beta chain
HOHILHGE_00768	9.37e-92	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HOHILHGE_00769	4.14e-42	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HOHILHGE_00770	2.87e-34	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HOHILHGE_00771	2.84e-37	-	-	-	M	-	-	-	domain protein
HOHILHGE_00772	1.4e-56	-	-	-	M	-	-	-	LPXTG-motif cell wall anchor domain protein
HOHILHGE_00773	2.57e-35	lutA	-	-	C	ko:K18928	-	ko00000	Cysteine-rich domain
HOHILHGE_00774	4.28e-274	mvaS	2.3.3.10	-	I	ko:K01641	ko00072,ko00280,ko00650,ko00900,ko01100,ko01110,ko01130,map00072,map00280,map00650,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA synthase
HOHILHGE_00775	4.36e-149	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HOHILHGE_00776	1.97e-49	ynzC	-	-	S	-	-	-	UPF0291 protein
HOHILHGE_00777	1.05e-36	XK26_06720	-	-	S	ko:K09976	-	ko00000	Uncharacterised protein family (UPF0154)
HOHILHGE_00778	3.58e-147	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Acyltransferase
HOHILHGE_00779	2.3e-174	yabB	2.1.1.223	-	L	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HOHILHGE_00780	2.67e-62	yazA	-	-	L	ko:K07461	-	ko00000	GIY-YIG catalytic domain protein
HOHILHGE_00781	3.67e-180	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HOHILHGE_00782	6.85e-197	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HOHILHGE_00783	6.84e-167	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HOHILHGE_00784	4.39e-120	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HOHILHGE_00785	2.22e-184	uppS	2.5.1.31	-	H	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HOHILHGE_00786	4.75e-173	cdsA	2.7.7.41	-	I	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HOHILHGE_00787	7.35e-290	rseP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HOHILHGE_00788	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HOHILHGE_00789	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HOHILHGE_00790	3.13e-273	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine
HOHILHGE_00791	1.89e-172	argB	2.7.2.8	-	F	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HOHILHGE_00792	1.22e-264	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HOHILHGE_00793	6.79e-249	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HOHILHGE_00794	2.42e-261	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HOHILHGE_00795	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOHILHGE_00796	8.99e-109	rimP	-	-	J	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HOHILHGE_00797	6.7e-283	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HOHILHGE_00798	3.71e-64	ylxR	-	-	K	ko:K07742	-	ko00000	Protein of unknown function (DUF448)
HOHILHGE_00799	5.5e-67	ylxQ	-	-	J	-	-	-	ribosomal protein
HOHILHGE_00800	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HOHILHGE_00801	1.49e-77	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HOHILHGE_00802	3.22e-214	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HOHILHGE_00803	3.14e-228	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HOHILHGE_00804	2.37e-165	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_00805	3.86e-314	-	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOHILHGE_00806	2.11e-167	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00807	3.93e-72	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOHILHGE_00808	4.76e-75	-	-	-	L	-	-	-	Helix-turn-helix domain
HOHILHGE_00809	1.09e-271	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00810	1.04e-32	traI	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HOHILHGE_00811	3.87e-114	-	-	-	-	-	-	-	-
HOHILHGE_00812	3.37e-96	asp1	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HOHILHGE_00813	3.42e-41	-	-	-	S	-	-	-	Transglycosylase associated protein
HOHILHGE_00814	2.59e-137	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00815	7.94e-75	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00816	1.58e-79	-	-	-	-	-	-	-	-
HOHILHGE_00817	8.11e-241	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HOHILHGE_00818	1.69e-87	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOHILHGE_00819	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HOHILHGE_00820	1.9e-261	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HOHILHGE_00821	2.18e-121	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HOHILHGE_00822	2.15e-11	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOHILHGE_00823	2.73e-49	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HOHILHGE_00824	4.55e-74	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HOHILHGE_00825	2.63e-69	hisE	3.6.1.31	-	E	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	phosphoribosyl-ATP diphosphatase activity
HOHILHGE_00826	1.28e-254	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HOHILHGE_00827	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HOHILHGE_00828	1.37e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_00830	5.07e-143	pgm1	-	-	G	-	-	-	phosphoglycerate mutase
HOHILHGE_00831	6.56e-125	-	-	-	C	-	-	-	aldo keto reductase
HOHILHGE_00832	4.3e-252	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HOHILHGE_00833	1.03e-282	serA	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_00834	3.13e-158	-	-	-	L	-	-	-	Transposase and inactivated derivatives IS30 family
HOHILHGE_00835	2.29e-42	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HOHILHGE_00836	1.65e-18	-	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HOHILHGE_00837	2.43e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00838	3.86e-282	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Aminotransferase class V
HOHILHGE_00840	7.41e-313	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00841	4.21e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_00842	2.34e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00843	2.74e-46	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	ThiS family
HOHILHGE_00844	9.1e-22	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HOHILHGE_00845	2.33e-58	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HOHILHGE_00846	2e-102	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HOHILHGE_00847	3.34e-104	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
HOHILHGE_00848	4.71e-148	narK	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	Major Facilitator Superfamily
HOHILHGE_00849	1.94e-76	-	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HOHILHGE_00850	1.85e-207	-	-	-	K	ko:K20480	ko02024,map02024	ko00000,ko00001,ko03000	Helix-turn-helix
HOHILHGE_00851	1.33e-167	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HOHILHGE_00852	1.37e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_00853	7.85e-175	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOHILHGE_00854	2.6e-75	-	-	-	L	-	-	-	Helix-turn-helix domain
HOHILHGE_00855	1.07e-178	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00856	1.29e-14	ydgH	-	-	S	ko:K06994	-	ko00000	MMPL family
HOHILHGE_00857	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HOHILHGE_00858	9.42e-122	-	-	-	V	-	-	-	VanZ like family
HOHILHGE_00859	1.4e-282	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HOHILHGE_00860	1.08e-78	-	-	-	-	-	-	-	-
HOHILHGE_00861	5.2e-229	-	-	-	K	ko:K02525	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOHILHGE_00862	7.81e-300	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	Gluconate
HOHILHGE_00863	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HOHILHGE_00864	1.12e-217	-	-	-	K	ko:K20375	ko02024,map02024	ko00000,ko00001,ko03000	Transcriptional activator, Rgg GadR MutR family
HOHILHGE_00867	1.37e-10	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HOHILHGE_00868	8.75e-169	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
HOHILHGE_00869	3.24e-50	pacL2	3.6.3.2, 3.6.3.6, 3.6.3.8	-	P	ko:K01531,ko:K01535,ko:K01537,ko:K12952	ko00190,map00190	ko00000,ko00001,ko01000	P-type ATPase
HOHILHGE_00870	1.8e-72	-	3.6.3.6, 3.6.3.8	-	P	ko:K01535,ko:K01537,ko:K12955	ko00190,map00190	ko00000,ko00001,ko01000	ATPase, P-type (transporting), HAD superfamily, subfamily IC
HOHILHGE_00871	1.24e-33	-	3.6.3.6	-	P	ko:K01535	ko00190,map00190	ko00000,ko00001,ko01000	Cation transporter/ATPase, N-terminus
HOHILHGE_00873	1.71e-105	atkY	-	-	K	ko:K02171	ko01501,map01501	ko00000,ko00001,ko00002,ko01504,ko03000	Copper transport repressor CopY TcrY
HOHILHGE_00874	3.92e-55	-	-	-	-	-	-	-	-
HOHILHGE_00875	2.04e-205	-	-	-	GK	-	-	-	ROK family
HOHILHGE_00876	2.9e-164	-	-	-	C	-	-	-	Oxidoreductase NAD-binding domain
HOHILHGE_00877	0.0	ubiB	-	-	S	ko:K03688	-	ko00000	ABC1 family
HOHILHGE_00878	6.33e-133	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HOHILHGE_00879	2.51e-90	-	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HOHILHGE_00880	3.49e-72	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOHILHGE_00881	7.4e-71	crcB	-	-	U	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HOHILHGE_00882	6.38e-197	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOHILHGE_00883	3.21e-54	-	-	-	L	-	-	-	Helix-turn-helix domain
HOHILHGE_00884	2.41e-128	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HOHILHGE_00886	0.0	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HOHILHGE_00887	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HOHILHGE_00888	2.92e-145	ybbL	-	-	S	ko:K02068	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00889	3.62e-169	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	Uncharacterised protein family (UPF0014)
HOHILHGE_00890	3.21e-143	glpQ1	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HOHILHGE_00891	7.69e-74	arsC	1.20.4.1	-	T	ko:K03741	-	ko00000,ko01000	Low molecular weight phosphotyrosine protein phosphatase
HOHILHGE_00892	1.62e-275	-	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	succinyl-diaminopimelate desuccinylase
HOHILHGE_00893	0.0	guaD	3.5.4.3	-	F	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Amidohydrolase family
HOHILHGE_00894	4.88e-197	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00895	1.11e-59	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00896	5.69e-280	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_00898	8.93e-185	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HOHILHGE_00900	1.6e-269	-	-	-	I	-	-	-	transferase activity, transferring acyl groups other than amino-acyl groups
HOHILHGE_00902	1.26e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HOHILHGE_00903	2.92e-127	-	-	-	K	-	-	-	Virulence activator alpha C-term
HOHILHGE_00904	3.37e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Belongs to the NDK family
HOHILHGE_00905	8.86e-70	-	-	-	S	-	-	-	SNARE associated Golgi protein
HOHILHGE_00906	5.06e-300	-	-	-	N	ko:K09384	-	ko00000	Uncharacterized conserved protein (DUF2075)
HOHILHGE_00907	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HOHILHGE_00909	0.0	yifK	-	-	E	ko:K03293	-	ko00000	Amino acid permease
HOHILHGE_00910	1.21e-240	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_00912	0.0	pepDA	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOHILHGE_00913	1.11e-208	endA	-	-	F	ko:K15051	-	ko00000	DNA RNA non-specific endonuclease
HOHILHGE_00914	6.72e-210	-	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	3-hydroxyacyl-CoA dehydrogenase
HOHILHGE_00915	0.0	-	-	-	I	-	-	-	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HOHILHGE_00916	5.3e-207	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOHILHGE_00918	7.93e-291	-	-	-	-	-	-	-	-
HOHILHGE_00919	2.37e-249	flp	-	-	V	-	-	-	Beta-lactamase
HOHILHGE_00920	8.23e-117	pgpA	-	-	I	-	-	-	Phosphatidylglycerophosphatase A
HOHILHGE_00921	2.7e-76	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOHILHGE_00922	1.46e-58	-	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HOHILHGE_00923	8.22e-233	XK27_12525	-	-	S	-	-	-	AI-2E family transporter
HOHILHGE_00924	1.27e-271	atoB	1.1.1.88, 2.3.1.9	-	I	ko:K00054,ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HOHILHGE_00925	3.32e-205	rssA	-	-	S	-	-	-	Phospholipase, patatin family
HOHILHGE_00926	1.69e-208	-	-	-	K	-	-	-	LysR substrate binding domain
HOHILHGE_00927	5.69e-13	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOHILHGE_00928	0.0	-	1.3.5.4	-	C	ko:K00244	ko00020,ko00190,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,map00020,map00190,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020	ko00000,ko00001,ko00002,ko01000	FAD binding domain
HOHILHGE_00929	1.18e-106	-	-	-	S	-	-	-	Domain of unknown function (DUF4352)
HOHILHGE_00930	2.02e-144	yicL	-	-	EG	-	-	-	EamA-like transporter family
HOHILHGE_00931	1.53e-83	-	-	-	-	-	-	-	-
HOHILHGE_00933	5.05e-45	-	-	-	-	-	-	-	-
HOHILHGE_00934	2.29e-88	-	-	-	S	-	-	-	pyridoxamine 5-phosphate
HOHILHGE_00935	7.32e-228	-	-	-	K	-	-	-	WYL domain
HOHILHGE_00936	7.71e-311	XK27_08635	-	-	S	ko:K09157	-	ko00000	UPF0210 protein
HOHILHGE_00937	1.65e-53	XK27_08630	-	-	T	ko:K07166	-	ko00000	Belongs to the UPF0237 family
HOHILHGE_00938	3.34e-214	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HOHILHGE_00939	7.93e-270	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HOHILHGE_00940	1.99e-260	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HOHILHGE_00941	3.12e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00942	6.19e-100	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_00943	1.21e-135	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_00944	8.68e-35	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOHILHGE_00945	6.76e-10	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HOHILHGE_00946	1.79e-214	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00947	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HOHILHGE_00948	1.03e-87	citC	6.2.1.22	-	H	ko:K01910	ko02020,map02020	ko00000,ko00001,ko01000	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HOHILHGE_00949	9.29e-183	citE	4.1.3.34	-	G	ko:K01644	ko02020,map02020	ko00000,ko00001,ko01000	Belongs to the HpcH HpaI aldolase family
HOHILHGE_00950	6.75e-273	citF	2.8.3.10	-	H	ko:K01643	ko02020,map02020	ko00000,ko00001,ko01000	Citrate (pro-3S)-lyase alpha chain
HOHILHGE_00951	8.78e-111	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HOHILHGE_00952	1.14e-44	citG	2.4.2.52	-	H	ko:K05966	ko02020,map02020	ko00000,ko00001,ko01000	2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HOHILHGE_00954	6.82e-53	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HOHILHGE_00955	1.04e-136	-	-	-	L	-	-	-	Integrase
HOHILHGE_00956	7.52e-133	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HOHILHGE_00957	8.33e-61	-	-	-	L	ko:K07483	-	ko00000	Transposase
HOHILHGE_00958	2.63e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_00959	2.43e-52	-	-	-	L	-	-	-	Helix-turn-helix domain
HOHILHGE_00960	2.99e-93	-	-	-	L	ko:K07497	-	ko00000	hmm pf00665
HOHILHGE_00961	2.11e-65	-	-	-	M	-	-	-	Protein of unknown function (DUF3737)
HOHILHGE_00962	2.68e-100	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOHILHGE_00963	1.55e-61	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOHILHGE_00965	2.4e-282	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00966	3.78e-109	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HOHILHGE_00967	3.81e-111	-	-	-	U	ko:K05340	-	ko00000,ko02000	sugar transport
HOHILHGE_00968	5.08e-14	-	-	-	S	-	-	-	NAD(P)H dehydrogenase (quinone) activity
HOHILHGE_00969	3.79e-30	-	-	-	GM	-	-	-	NmrA-like family
HOHILHGE_00971	1.35e-71	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HOHILHGE_00972	1.2e-60	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_00973	5.38e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_00974	2.2e-167	-	-	-	L	-	-	-	Probable transposase
HOHILHGE_00975	5.38e-29	-	-	-	EGP	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HOHILHGE_00976	2.5e-13	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOHILHGE_00977	9.99e-40	paiA	2.3.1.57	-	K	ko:K22441	-	ko00000,ko01000	Acetyltransferase (GNAT) domain
HOHILHGE_00978	5.23e-97	-	-	-	O	ko:K07397	-	ko00000	OsmC-like protein
HOHILHGE_00979	9.93e-99	ywnA	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_00980	2.24e-206	proWY	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, substrate-binding protein, QAT family
HOHILHGE_00981	2.98e-137	proWZ	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOHILHGE_00982	1.62e-181	proV	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_00983	5.36e-130	-	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, permease protein
HOHILHGE_00984	1.86e-167	-	-	-	C	-	-	-	Zinc-binding dehydrogenase
HOHILHGE_00985	6.24e-245	bdhA	1.1.1.14, 1.1.1.264, 1.1.1.303, 1.1.1.4	-	C	ko:K00004,ko:K00008,ko:K00098	ko00040,ko00051,ko00650,ko01100,map00040,map00051,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Zinc-binding dehydrogenase
HOHILHGE_00986	4.4e-41	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOHILHGE_00987	2.41e-216	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase, class I
HOHILHGE_00988	6.33e-226	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HOHILHGE_00989	2.31e-256	xerS	-	-	L	ko:K04763	-	ko00000,ko03036	Belongs to the 'phage' integrase family
HOHILHGE_00990	1.65e-52	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOHILHGE_00992	8.3e-264	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	Isocitrate/isopropylmalate dehydrogenase
HOHILHGE_00993	6.38e-194	pdxK	2.7.1.35	-	H	ko:K00868	ko00750,ko01100,map00750,map01100	ko00000,ko00001,ko01000	Phosphomethylpyrimidine kinase
HOHILHGE_00994	2.16e-104	-	-	-	S	-	-	-	ECF-type riboflavin transporter, S component
HOHILHGE_00996	1.86e-20	yvgN	-	-	C	-	-	-	Aldo keto reductase
HOHILHGE_00997	8.19e-132	yvgN	-	-	C	-	-	-	Aldo keto reductase
HOHILHGE_00998	3.41e-205	-	-	-	S	-	-	-	DUF218 domain
HOHILHGE_01000	1.41e-06	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2316)
HOHILHGE_01001	3.05e-121	-	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HOHILHGE_01002	4.32e-172	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOHILHGE_01003	6.15e-26	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOHILHGE_01004	3.85e-141	-	-	-	S	-	-	-	Phage minor capsid protein 2
HOHILHGE_01007	1.47e-266	-	-	-	E	-	-	-	Aminotransferase
HOHILHGE_01008	2.26e-234	-	4.3.1.12	-	E	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	ko00000,ko00001,ko01000	Ornithine cyclodeaminase/mu-crystallin family
HOHILHGE_01009	4.19e-134	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HOHILHGE_01010	1.18e-17	-	-	-	EGP	ko:K08368	-	ko00000,ko02000	Sugar (and other) transporter
HOHILHGE_01011	5.38e-125	-	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Phosphoribosyl transferase domain
HOHILHGE_01012	5.5e-118	-	-	-	S	-	-	-	Fic/DOC family
HOHILHGE_01013	1.31e-110	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOHILHGE_01014	4.09e-136	lacA	2.3.1.18, 2.3.1.79	-	S	ko:K00633,ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOHILHGE_01015	2.21e-255	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HOHILHGE_01016	6.96e-163	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01017	2.91e-166	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_01018	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01019	1.43e-07	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
HOHILHGE_01020	7.66e-308	-	-	-	E	ko:K03758	-	ko00000,ko02000	Amino acid permease
HOHILHGE_01021	8.34e-153	-	-	-	M	-	-	-	racemase activity, acting on amino acids and derivatives
HOHILHGE_01022	9.08e-197	-	-	-	C	-	-	-	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
HOHILHGE_01023	3.45e-26	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOHILHGE_01024	3e-60	eriC	-	-	P	ko:K03281	-	ko00000	chloride
HOHILHGE_01025	3.57e-22	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOHILHGE_01027	1.95e-308	yhjX	-	-	P	ko:K08177	-	ko00000,ko02000	Major Facilitator Superfamily
HOHILHGE_01028	1.57e-19	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HOHILHGE_01029	0.0	rarA	-	-	L	ko:K07478	-	ko00000	recombination factor protein RarA
HOHILHGE_01031	0.0	-	-	-	EP	-	-	-	Psort location Cytoplasmic, score
HOHILHGE_01032	3.75e-307	codA	3.5.4.1	-	F	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	ko00000,ko00001,ko01000	cytosine deaminase
HOHILHGE_01033	9.78e-312	-	-	-	U	-	-	-	Belongs to the purine-cytosine permease (2.A.39) family
HOHILHGE_01034	9.1e-105	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HOHILHGE_01035	5.98e-121	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	Acetyltransferase (GNAT) domain
HOHILHGE_01036	6.11e-96	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HOHILHGE_01037	3.9e-90	-	-	-	S	-	-	-	Belongs to the HesB IscA family
HOHILHGE_01038	1.87e-219	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	inorganic pyrophosphatase
HOHILHGE_01039	2.08e-122	-	-	-	S	ko:K08996	-	ko00000	Protein of unknown function (DUF1440)
HOHILHGE_01040	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOHILHGE_01041	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HOHILHGE_01042	5.26e-134	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HOHILHGE_01043	2.19e-218	lacX	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HOHILHGE_01044	2.24e-198	-	-	-	D	-	-	-	DNA integration
HOHILHGE_01045	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HOHILHGE_01046	3.47e-210	dprA	-	-	LU	ko:K04096	-	ko00000	DNA protecting protein DprA
HOHILHGE_01047	2.05e-180	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HOHILHGE_01048	1.78e-207	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HOHILHGE_01049	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HOHILHGE_01050	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01051	4.96e-104	ypmS	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2140)
HOHILHGE_01052	3.49e-217	-	-	-	E	-	-	-	lipolytic protein G-D-S-L family
HOHILHGE_01053	9.86e-146	cat	2.3.1.79	-	S	ko:K00661,ko:K18234	-	ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HOHILHGE_01054	1.27e-272	-	1.1.1.399, 1.1.1.95	-	EH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	D-isomer specific 2-hydroxyacid dehydrogenase
HOHILHGE_01055	3.03e-194	WQ51_01275	-	-	S	-	-	-	EDD domain protein, DegV family
HOHILHGE_01056	1.82e-137	hlyIII	-	-	S	ko:K11068	-	ko00000,ko02042	protein, hemolysin III
HOHILHGE_01057	1.04e-120	folA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HOHILHGE_01058	8.83e-243	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HOHILHGE_01059	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01060	6.2e-284	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOHILHGE_01061	3.71e-211	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
HOHILHGE_01062	2.07e-299	XK27_05225	-	-	S	-	-	-	Tetratricopeptide repeat protein
HOHILHGE_01063	2.65e-53	hup	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HOHILHGE_01064	1.29e-313	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HOHILHGE_01065	6.57e-275	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HOHILHGE_01066	2.29e-153	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HOHILHGE_01067	1.78e-75	-	-	-	M	-	-	-	Lysin motif
HOHILHGE_01068	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase RecQ
HOHILHGE_01069	1.34e-254	-	-	-	S	-	-	-	Helix-turn-helix domain
HOHILHGE_01070	1.18e-111	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HOHILHGE_01071	1.68e-167	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HOHILHGE_01072	3.2e-131	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HOHILHGE_01073	1.18e-182	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HOHILHGE_01074	6.14e-87	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HOHILHGE_01075	1.21e-174	xerD	-	-	D	ko:K04763	-	ko00000,ko03036	recombinase XerD
HOHILHGE_01076	3.62e-214	yitL	-	-	S	ko:K00243	-	ko00000	S1 domain
HOHILHGE_01077	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HOHILHGE_01078	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HOHILHGE_01080	2.07e-300	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HOHILHGE_01081	4.03e-200	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HOHILHGE_01082	8.01e-162	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HOHILHGE_01083	3.26e-152	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	domain protein
HOHILHGE_01084	8.31e-294	ktrB	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium uptake protein
HOHILHGE_01085	2.89e-250	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HOHILHGE_01086	3.27e-276	aspC	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HOHILHGE_01087	2.21e-181	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HOHILHGE_01088	4.26e-221	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HOHILHGE_01089	6.36e-278	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HOHILHGE_01090	2.59e-114	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HOHILHGE_01091	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HOHILHGE_01092	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HOHILHGE_01093	3.39e-230	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HOHILHGE_01094	2.86e-215	apbE	2.7.1.180	-	H	ko:K03734	-	ko00000,ko01000	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HOHILHGE_01095	9.86e-42	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_01096	1.68e-91	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_01097	1.15e-66	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01098	1.78e-284	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_01099	1.91e-261	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HOHILHGE_01100	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HOHILHGE_01101	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HOHILHGE_01102	3.59e-240	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HOHILHGE_01103	2.62e-200	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HOHILHGE_01104	7.33e-217	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HOHILHGE_01105	7.34e-86	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HOHILHGE_01106	1.38e-102	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HOHILHGE_01107	3.02e-229	phoH	-	-	T	ko:K06217	-	ko00000	phosphate starvation-inducible protein PhoH
HOHILHGE_01108	3.73e-94	yqeY	-	-	S	ko:K09117	-	ko00000	YqeY-like protein
HOHILHGE_01109	3.81e-31	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HOHILHGE_01110	2.6e-164	-	-	-	F	-	-	-	glutamine amidotransferase
HOHILHGE_01111	2.83e-81	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_01112	2.32e-208	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_01113	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HOHILHGE_01114	3.98e-314	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HOHILHGE_01115	2.99e-248	-	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HOHILHGE_01116	4.44e-226	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Ami_3
HOHILHGE_01117	4.58e-216	-	-	-	G	-	-	-	Phosphotransferase enzyme family
HOHILHGE_01118	5.14e-208	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine S-methyltransferase
HOHILHGE_01119	9.99e-147	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_01120	1.45e-197	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to
HOHILHGE_01121	3.35e-270	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Homoserine dehydrogenase
HOHILHGE_01123	4.47e-175	-	-	-	IQ	-	-	-	KR domain
HOHILHGE_01124	2.14e-196	cjaA	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter substrate-binding protein
HOHILHGE_01125	3.4e-174	glnQ	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01126	3.24e-147	glnP7	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter permease
HOHILHGE_01127	3.25e-145	glnP9	-	-	P	ko:K02029	-	ko00000,ko00002,ko02000	ABC transporter, permease protein
HOHILHGE_01129	1.23e-32	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HOHILHGE_01130	3.06e-79	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HOHILHGE_01131	4.43e-86	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Cys/Met metabolism PLP-dependent enzyme
HOHILHGE_01132	1.23e-273	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HOHILHGE_01133	7.99e-106	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_01134	3.12e-100	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HOHILHGE_01135	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HOHILHGE_01136	4.23e-76	-	-	-	-	-	-	-	-
HOHILHGE_01137	1.75e-173	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HOHILHGE_01138	3.03e-230	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Ribosomal protein L11 methyltransferase
HOHILHGE_01139	4.82e-72	-	-	-	-	-	-	-	-
HOHILHGE_01141	5.81e-222	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HOHILHGE_01142	6.18e-122	-	-	-	S	-	-	-	integral membrane protein
HOHILHGE_01143	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOHILHGE_01144	7.27e-118	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOHILHGE_01145	8.89e-39	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HOHILHGE_01146	5.43e-185	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HOHILHGE_01147	1.18e-54	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOHILHGE_01148	1.66e-59	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HOHILHGE_01149	2.77e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HOHILHGE_01150	6.23e-92	psiE	-	-	S	ko:K13256	-	ko00000	Phosphate-starvation-inducible E
HOHILHGE_01151	4.53e-127	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOHILHGE_01152	2.95e-202	-	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOHILHGE_01153	5.05e-136	msrA	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HOHILHGE_01154	1.81e-150	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HOHILHGE_01155	1.01e-128	cadD	-	-	P	-	-	-	Cadmium resistance transporter
HOHILHGE_01156	1.92e-302	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01157	5.98e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_01158	1.18e-42	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HOHILHGE_01159	8.77e-23	moaE	2.8.1.12	-	H	ko:K03635,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	MoaE protein
HOHILHGE_01160	1.27e-270	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_01161	4.44e-292	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HOHILHGE_01162	2.45e-70	yitW	-	-	S	-	-	-	Iron-sulfur cluster assembly protein
HOHILHGE_01163	4.95e-25	-	-	-	S	-	-	-	Domain of unknown function (DUF1858)
HOHILHGE_01164	0.0	XK27_04775	-	-	S	ko:K09155	-	ko00000	PAS domain
HOHILHGE_01165	3.04e-133	-	-	-	EG	-	-	-	EamA-like transporter family
HOHILHGE_01166	3.13e-40	-	-	-	EG	-	-	-	EamA-like transporter family
HOHILHGE_01167	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01168	4.52e-240	fecB	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HOHILHGE_01169	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	assembly protein SufB
HOHILHGE_01170	2.14e-110	nifU	-	-	C	ko:K04488	-	ko00000	SUF system FeS assembly protein, NifU family
HOHILHGE_01171	2.14e-297	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HOHILHGE_01172	2.57e-310	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	FeS assembly protein SufD
HOHILHGE_01173	6.61e-186	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	FeS assembly ATPase SufC
HOHILHGE_01174	2e-45	feoA	-	-	P	ko:K04758	-	ko00000,ko02000	FeoA domain
HOHILHGE_01175	1.24e-213	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HOHILHGE_01176	9.89e-226	feoB	-	-	P	ko:K04759	-	ko00000,ko02000	transporter of a GTP-driven Fe(2 ) uptake system
HOHILHGE_01177	1.25e-31	-	-	-	S	-	-	-	Virus attachment protein p12 family
HOHILHGE_01178	3.15e-201	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	1,4-dihydroxy-2-naphthoate
HOHILHGE_01179	6.05e-225	hepT	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOHILHGE_01180	2.41e-235	-	1.1.1.28	-	CH	ko:K03778	ko00620,ko01120,map00620,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_01181	1.5e-277	aspB3	-	-	E	-	-	-	DegT/DnrJ/EryC1/StrS aminotransferase family
HOHILHGE_01182	3.56e-115	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HOHILHGE_01183	2.18e-246	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HOHILHGE_01184	1.51e-298	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HOHILHGE_01185	2.06e-121	-	-	-	-	-	-	-	-
HOHILHGE_01186	4.42e-271	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HOHILHGE_01187	8.93e-14	tyrA	4.2.1.51, 5.4.99.5	-	E	ko:K04516,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	chorismate mutase
HOHILHGE_01188	4.99e-273	-	-	-	G	-	-	-	Major Facilitator Superfamily
HOHILHGE_01190	0.0	dtpT	-	-	U	ko:K03305	-	ko00000	amino acid peptide transporter
HOHILHGE_01192	2.24e-196	supH	-	-	S	-	-	-	Sucrose-6F-phosphate phosphohydrolase
HOHILHGE_01193	1.07e-202	-	-	-	GM	-	-	-	NAD(P)H-binding
HOHILHGE_01194	2.95e-203	-	-	-	S	-	-	-	Alpha beta hydrolase
HOHILHGE_01195	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01196	1.37e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01197	7.75e-121	lmrB	-	-	U	ko:K18926	-	ko00000,ko00002,ko02000	Belongs to the major facilitator superfamily
HOHILHGE_01199	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HOHILHGE_01200	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01201	3.46e-65	-	-	-	-	-	-	-	-
HOHILHGE_01202	0.0	kup	-	-	P	ko:K03549	-	ko00000,ko02000	Transport of potassium into the cell
HOHILHGE_01204	0.0	glpK	2.7.1.30	-	F	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HOHILHGE_01205	4.64e-36	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Belongs to the 4-oxalocrotonate tautomerase family
HOHILHGE_01206	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	TrkA C-terminal domain protein
HOHILHGE_01207	0.0	pepD4	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOHILHGE_01208	2.82e-204	-	-	-	S	-	-	-	Alpha/beta hydrolase of unknown function (DUF915)
HOHILHGE_01209	1.77e-299	pts13C	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HOHILHGE_01210	3.52e-57	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOHILHGE_01211	1.26e-213	prpA3	3.1.3.16	-	T	ko:K01090	-	ko00000,ko01000	Calcineurin-like phosphoesterase superfamily domain
HOHILHGE_01212	3.85e-202	-	-	-	EGP	ko:K18934	-	ko00000,ko02000	Major Facilitator Superfamily
HOHILHGE_01213	1.16e-267	mdtG2	-	-	EGP	ko:K08161	-	ko00000,ko02000	Transporter, major facilitator family protein
HOHILHGE_01214	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HOHILHGE_01215	2.98e-270	-	-	-	EGP	ko:K08196	-	ko00000,ko02000	Major Facilitator
HOHILHGE_01216	6.18e-21	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HOHILHGE_01217	3.39e-64	lysR	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_01218	4.46e-22	rlrB	-	-	K	-	-	-	LysR substrate binding domain protein
HOHILHGE_01219	1.67e-272	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOHILHGE_01220	4.77e-248	lplA	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HOHILHGE_01221	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	Dehydrogenase
HOHILHGE_01222	2.54e-274	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HOHILHGE_01223	6.09e-228	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Transketolase, C-terminal domain protein
HOHILHGE_01224	4.9e-232	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	Dehydrogenase E1 component
HOHILHGE_01225	3.2e-70	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	decarboxylase
HOHILHGE_01226	5.84e-57	azlD	-	-	E	-	-	-	Branched-chain amino acid transport
HOHILHGE_01227	4.17e-95	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HOHILHGE_01228	3.8e-27	azlC	-	-	E	-	-	-	azaleucine resistance protein AzlC
HOHILHGE_01229	0.0	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Threonine synthase
HOHILHGE_01230	1.62e-294	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HOHILHGE_01231	1.4e-202	thrB	2.7.1.39	-	F	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HOHILHGE_01232	2.42e-127	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HOHILHGE_01233	1.24e-146	ylbE	-	-	GM	-	-	-	NAD(P)H-binding
HOHILHGE_01234	1.19e-151	yagB	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOHILHGE_01235	1.55e-170	yaaA	-	-	S	ko:K09861	-	ko00000	Belongs to the UPF0246 family
HOHILHGE_01236	9.35e-128	-	-	-	-	-	-	-	-
HOHILHGE_01237	2.72e-203	-	-	-	S	-	-	-	EDD domain protein, DegV family
HOHILHGE_01238	3.06e-178	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01239	0.0	FbpA	-	-	K	-	-	-	Fibronectin-binding protein
HOHILHGE_01240	2.03e-123	-	-	-	P	-	-	-	nitric oxide dioxygenase activity
HOHILHGE_01241	5.61e-63	-	-	-	C	-	-	-	Flavodoxin
HOHILHGE_01242	1.29e-26	-	-	-	S	-	-	-	Bacterial transferase hexapeptide (six repeats)
HOHILHGE_01244	5.85e-84	-	1.1.1.346	-	S	ko:K06221	-	ko00000,ko01000	Aldo/keto reductase family
HOHILHGE_01245	3.08e-100	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01247	2.61e-134	-	-	-	K	-	-	-	Bacterial regulatory helix-turn-helix protein, lysR family
HOHILHGE_01248	1.78e-154	-	4.2.1.1	-	P	ko:K01674	ko00910,map00910	ko00000,ko00001,ko01000	Eukaryotic-type carbonic anhydrase
HOHILHGE_01249	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOHILHGE_01250	2.43e-263	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarA family
HOHILHGE_01251	2.12e-222	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOHILHGE_01252	1.27e-99	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HOHILHGE_01253	8.6e-93	esbA	-	-	S	-	-	-	Family of unknown function (DUF5322)
HOHILHGE_01254	1.73e-89	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease HI
HOHILHGE_01255	1.36e-139	XK27_02070	-	-	S	ko:K07078	-	ko00000	Nitroreductase family
HOHILHGE_01256	8.4e-200	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HOHILHGE_01257	4.1e-153	yckA	-	-	E	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOHILHGE_01258	1.05e-05	-	-	-	M	-	-	-	Glycosyltransferase like family 2
HOHILHGE_01259	5.17e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01260	9.03e-279	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HOHILHGE_01261	5.76e-107	-	-	-	F	-	-	-	Hydrolase, NUDIX family
HOHILHGE_01262	4.18e-269	-	-	-	S	ko:K06915	-	ko00000	AAA-like domain
HOHILHGE_01263	0.0	fusA1	-	-	J	-	-	-	elongation factor G
HOHILHGE_01264	9.5e-21	-	-	-	L	-	-	-	transposase and inactivated derivatives, IS30 family
HOHILHGE_01265	8.44e-109	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01266	2.08e-75	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HOHILHGE_01267	1.21e-141	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HOHILHGE_01268	5.72e-151	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HOHILHGE_01269	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein 1A
HOHILHGE_01270	9.03e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HOHILHGE_01271	2.73e-242	tas3	-	-	C	ko:K19265	-	ko00000,ko01000	Aldo keto reductase family protein
HOHILHGE_01272	1.21e-186	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
HOHILHGE_01273	1.69e-172	dnaD	-	-	L	ko:K02086	-	ko00000	DnaD domain protein
HOHILHGE_01274	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Asparaginyl-tRNA synthetase
HOHILHGE_01275	2.23e-113	ypmB	-	-	S	-	-	-	Protein conserved in bacteria
HOHILHGE_01276	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HOHILHGE_01277	6.21e-214	mvk	2.7.1.36	-	I	ko:K00869	ko00900,ko01100,ko01110,ko01130,ko04146,map00900,map01100,map01110,map01130,map04146	ko00000,ko00001,ko00002,ko01000	mevalonate kinase
HOHILHGE_01278	3.68e-231	mvaD	4.1.1.33	-	I	ko:K01597	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	diphosphomevalonate decarboxylase
HOHILHGE_01279	2.36e-270	mvaK2	2.7.4.2	-	I	ko:K00938	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	phosphomevalonate kinase
HOHILHGE_01280	5.29e-263	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HOHILHGE_01281	2.13e-117	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01282	1.52e-129	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HOHILHGE_01283	9.79e-122	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HOHILHGE_01284	2.1e-114	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HOHILHGE_01285	0.0	rsmF	-	-	J	-	-	-	NOL1 NOP2 sun family protein
HOHILHGE_01286	1.07e-197	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolase
HOHILHGE_01287	3.21e-213	pyrD	1.3.1.14, 1.3.98.1	-	F	ko:K00226,ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HOHILHGE_01288	1.87e-203	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOHILHGE_01289	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthase
HOHILHGE_01290	5.96e-264	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HOHILHGE_01291	3.8e-311	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HOHILHGE_01292	4.85e-232	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HOHILHGE_01293	8.56e-71	ycsI	-	-	S	-	-	-	Protein of unknown function (DUF1445)
HOHILHGE_01294	5.94e-100	cas2	-	-	L	ko:K09951	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas2CT1978)
HOHILHGE_01295	1.46e-158	cas1	-	-	L	ko:K15342	-	ko00000,ko02048,ko03400	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HOHILHGE_01296	9.63e-90	casE	-	-	S	ko:K19126	-	ko00000,ko02048	CRISPR_assoc
HOHILHGE_01297	1.33e-80	casD	-	-	S	ko:K19125	-	ko00000,ko02048	CRISPR-associated protein (Cas_Cas5)
HOHILHGE_01298	1.1e-163	casC	-	-	L	ko:K19124	-	ko00000,ko02048	CT1975-like protein
HOHILHGE_01299	3.93e-52	-	-	-	S	ko:K19046	-	ko00000,ko02048	CRISPR-associated protein Cse2 (CRISPR_cse2)
HOHILHGE_01300	8.43e-190	casA	-	-	L	ko:K19123	-	ko00000,ko02048	the current gene model (or a revised gene model) may contain a frame shift
HOHILHGE_01301	0.0	cas3	-	-	L	ko:K07012	-	ko00000,ko01000,ko02048	CRISPR-associated helicase cas3
HOHILHGE_01302	6.59e-76	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HOHILHGE_01303	0.0	-	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOHILHGE_01304	8.69e-180	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HOHILHGE_01305	1.52e-114	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HOHILHGE_01306	7.55e-53	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HOHILHGE_01307	4.94e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HOHILHGE_01308	1.13e-157	phoU	-	-	P	ko:K02039	-	ko00000	Plays a role in the regulation of phosphate uptake
HOHILHGE_01309	5.22e-176	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HOHILHGE_01310	7.93e-182	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease protein PstA
HOHILHGE_01311	3.76e-193	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HOHILHGE_01312	1.65e-176	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HOHILHGE_01313	1.59e-24	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HOHILHGE_01314	7.02e-123	-	-	-	K	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Transcriptional regulatory protein, C-terminal domain protein
HOHILHGE_01315	1.94e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01316	2.46e-106	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01317	3.31e-120	-	-	-	G	-	-	-	Belongs to the carbohydrate kinase PfkB family
HOHILHGE_01318	2.63e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01319	2.67e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01320	6.25e-225	-	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HOHILHGE_01321	4.98e-187	-	-	-	O	-	-	-	ADP-ribosylglycohydrolase
HOHILHGE_01322	1.32e-272	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_01323	2.63e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01324	1.35e-134	pncA	-	-	Q	-	-	-	Isochorismatase family
HOHILHGE_01325	7.25e-295	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOHILHGE_01326	1.31e-165	-	-	-	F	-	-	-	NUDIX domain
HOHILHGE_01327	0.0	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOHILHGE_01328	4.94e-75	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HOHILHGE_01329	5.67e-282	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOHILHGE_01330	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HOHILHGE_01331	3.99e-166	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HOHILHGE_01332	1.65e-47	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HOHILHGE_01333	3.48e-212	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HOHILHGE_01334	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HOHILHGE_01335	0.0	yloV	-	-	S	ko:K07030	-	ko00000	DAK2 domain fusion protein YloV
HOHILHGE_01336	2.03e-75	yloU	-	-	S	-	-	-	Asp23 family, cell envelope-related function
HOHILHGE_01337	5.82e-35	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HOHILHGE_01338	4.34e-159	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HOHILHGE_01339	1.1e-151	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HOHILHGE_01340	1.53e-211	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HOHILHGE_01341	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HOHILHGE_01342	3.95e-168	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HOHILHGE_01343	1.06e-313	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HOHILHGE_01344	9.3e-223	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HOHILHGE_01345	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HOHILHGE_01346	3.44e-281	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HOHILHGE_01347	6.37e-60	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HOHILHGE_01348	1.03e-146	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HOHILHGE_01350	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HOHILHGE_01351	4.92e-99	argR2	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HOHILHGE_01352	1.14e-189	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	Ribosomal RNA large subunit methyltransferase J
HOHILHGE_01353	2.81e-200	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HOHILHGE_01354	1.64e-25	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOHILHGE_01355	0.0	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HOHILHGE_01356	1.16e-205	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HOHILHGE_01357	1.9e-89	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HOHILHGE_01358	2.1e-94	WQ51_04310	-	-	S	ko:K10947	-	ko00000,ko03000	Asp23 family, cell envelope-related function
HOHILHGE_01359	4.18e-263	pepP	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	Creatinase/Prolidase N-terminal domain
HOHILHGE_01360	8.74e-62	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HOHILHGE_01361	1.2e-70	ysxB	-	-	J	ko:K07584	-	ko00000	Cysteine protease Prp
HOHILHGE_01362	1.89e-67	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HOHILHGE_01363	3.17e-149	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_01365	1.1e-120	-	-	-	S	-	-	-	Protein conserved in bacteria
HOHILHGE_01366	4.05e-227	-	-	-	-	-	-	-	-
HOHILHGE_01367	1.56e-200	-	-	-	-	-	-	-	-
HOHILHGE_01368	4.76e-19	-	-	-	-	-	-	-	-
HOHILHGE_01369	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HOHILHGE_01370	2.56e-220	miaA	2.5.1.75	-	F	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HOHILHGE_01371	2.04e-32	WQ51_02665	-	-	S	-	-	-	Protein of unknown function (DUF3042)
HOHILHGE_01372	5.91e-93	yqhL	-	-	P	-	-	-	Rhodanese-like protein
HOHILHGE_01373	1.01e-228	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HOHILHGE_01374	1.14e-48	yqgQ	-	-	S	-	-	-	Bacterial protein of unknown function (DUF910)
HOHILHGE_01375	4.06e-133	gluP	3.4.21.105	-	S	ko:K19225	-	ko00000,ko01000,ko01002	Peptidase, S54 family
HOHILHGE_01376	4.45e-128	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HOHILHGE_01377	7.58e-30	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HOHILHGE_01378	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HOHILHGE_01379	0.0	-	-	-	S	-	-	-	membrane
HOHILHGE_01380	1.81e-103	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOHILHGE_01381	2.93e-151	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HOHILHGE_01382	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOHILHGE_01383	1.49e-251	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HOHILHGE_01384	1.44e-78	yodB	-	-	K	-	-	-	Transcriptional regulator, HxlR family
HOHILHGE_01385	1.37e-115	XK27_09705	-	-	S	ko:K06950	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOHILHGE_01386	1.84e-180	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HOHILHGE_01387	3.32e-61	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HOHILHGE_01388	1.18e-198	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOHILHGE_01389	4.54e-91	def2	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins
HOHILHGE_01390	1.8e-296	-	-	-	V	-	-	-	MatE
HOHILHGE_01391	1.53e-100	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01392	3.97e-153	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_01393	1.52e-213	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01394	5.9e-51	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01395	2.83e-81	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_01396	0.0	arlS	2.7.13.3	-	T	ko:K18940	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HOHILHGE_01397	1.38e-155	csrR	-	-	K	-	-	-	response regulator
HOHILHGE_01398	7.89e-38	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HOHILHGE_01399	1.61e-125	ylbN	-	-	S	ko:K07040	-	ko00000	Uncharacterized ACR, COG1399
HOHILHGE_01400	4.6e-271	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HOHILHGE_01401	4.64e-178	yqeM	-	-	Q	-	-	-	Methyltransferase
HOHILHGE_01402	4.64e-76	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HOHILHGE_01403	5.53e-145	yqeK	-	-	H	-	-	-	Hydrolase, HD family
HOHILHGE_01404	5.4e-119	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HOHILHGE_01405	1.38e-65	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein
HOHILHGE_01406	6.57e-275	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	Ribosome biogenesis GTPase YqeH
HOHILHGE_01407	6.88e-125	yqeG	-	-	S	ko:K07015	-	ko00000	HAD phosphatase, family IIIA
HOHILHGE_01408	7.57e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HOHILHGE_01409	2.58e-24	-	-	-	S	-	-	-	Protein of unknown function (DUF1275)
HOHILHGE_01410	4.67e-75	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HOHILHGE_01411	5.22e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HOHILHGE_01412	6.95e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HOHILHGE_01413	3.11e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HOHILHGE_01414	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	replication initiation and membrane attachment
HOHILHGE_01415	1.99e-104	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HOHILHGE_01416	6.89e-136	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HOHILHGE_01417	7.57e-208	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HOHILHGE_01418	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HOHILHGE_01419	4.66e-178	yfhR3	-	-	S	ko:K06889	-	ko00000	Serine hydrolase (FSH1)
HOHILHGE_01420	2.5e-75	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01421	1.24e-146	ybhL	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HOHILHGE_01422	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HOHILHGE_01423	4.53e-152	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HOHILHGE_01424	1.53e-72	ytpP	-	-	CO	-	-	-	Thioredoxin
HOHILHGE_01425	1.61e-74	-	-	-	S	-	-	-	Small secreted protein
HOHILHGE_01426	9.51e-161	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HOHILHGE_01427	3.82e-275	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HOHILHGE_01428	1.06e-170	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01429	4.29e-101	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	histidine triad
HOHILHGE_01431	6.67e-192	prsA	5.2.1.8	-	M	ko:K07533	-	ko00000,ko01000,ko03110	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HOHILHGE_01432	4.48e-231	yhaM	-	-	S	ko:K03698	-	ko00000,ko01000,ko03019	Metal dependent phosphohydrolases with conserved 'HD' motif.
HOHILHGE_01433	3.95e-73	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HOHILHGE_01434	0.0	pbp2A	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HOHILHGE_01435	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HOHILHGE_01437	2.3e-51	-	-	-	-	-	-	-	-
HOHILHGE_01439	4.95e-256	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	dihydropteroate synthase
HOHILHGE_01440	5.11e-133	folQ	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Ham1 family
HOHILHGE_01441	1.03e-302	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HOHILHGE_01442	3.23e-133	folE	2.7.6.3, 3.5.4.16	-	F	ko:K00950,ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase 1
HOHILHGE_01443	1.77e-119	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HOHILHGE_01444	8.2e-81	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HOHILHGE_01445	4.79e-151	XK27_07085	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOHILHGE_01446	1.51e-233	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	Periplasmic binding proteins and sugar binding domain of LacI family
HOHILHGE_01447	1.71e-143	-	-	-	-	-	-	-	-
HOHILHGE_01448	3.06e-150	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HOHILHGE_01449	3.27e-240	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOHILHGE_01450	0.0	-	-	-	S	-	-	-	Putative peptidoglycan binding domain
HOHILHGE_01451	1.65e-112	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HOHILHGE_01452	0.0	pepV	3.5.1.18	-	E	ko:K01270,ko:K01274,ko:K01439	ko00300,ko00480,ko01100,ko01120,ko01230,map00300,map00480,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	dipeptidase PepV
HOHILHGE_01453	3.83e-198	nnrD	4.2.1.136, 5.1.99.6	-	H	ko:K17758,ko:K17759	-	ko00000,ko01000	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HOHILHGE_01454	3.87e-80	-	-	-	S	-	-	-	Domain of unknown function DUF302
HOHILHGE_01455	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	Polysaccharide biosynthesis protein
HOHILHGE_01456	1.64e-55	-	-	-	-	-	-	-	-
HOHILHGE_01457	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HOHILHGE_01458	2.41e-162	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HOHILHGE_01459	5.97e-284	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HOHILHGE_01460	1.87e-180	proB	2.7.2.11	-	F	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HOHILHGE_01461	3.78e-271	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HOHILHGE_01462	2.19e-271	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_01463	1.84e-63	-	-	-	-	-	-	-	-
HOHILHGE_01464	1.79e-214	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01465	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HOHILHGE_01466	6.37e-125	tag1	3.2.2.20	-	L	ko:K01246	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	glycosylase
HOHILHGE_01467	0.0	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_01468	3.59e-111	perR	-	-	P	ko:K03711,ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HOHILHGE_01469	3.17e-314	cycA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	Amino acid permease
HOHILHGE_01470	3.91e-31	-	-	-	-	-	-	-	-
HOHILHGE_01474	5.23e-160	-	-	-	K	-	-	-	Transcriptional regulator, TetR family
HOHILHGE_01475	2.79e-102	hsp1	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HOHILHGE_01476	7.27e-112	ykhA	3.1.2.20	-	I	ko:K01073	-	ko00000,ko01000	Thioesterase superfamily
HOHILHGE_01477	2.24e-96	-	-	-	M	-	-	-	LysM domain protein
HOHILHGE_01478	8.26e-143	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HOHILHGE_01479	1.47e-70	adh	1.1.1.1	-	C	ko:K00001,ko:K18369	ko00010,ko00071,ko00350,ko00625,ko00626,ko00640,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00640,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding dehydrogenase
HOHILHGE_01480	1.52e-300	-	-	-	F	ko:K03458	-	ko00000	Permease
HOHILHGE_01481	9.88e-205	-	-	-	O	-	-	-	Uncharacterized protein family (UPF0051)
HOHILHGE_01482	2.99e-144	nrdG	1.97.1.4	-	O	ko:K04068	-	ko00000,ko01000	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HOHILHGE_01483	0.0	nrdD	1.1.98.6	-	F	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Ribonucleoside-triphosphate reductase
HOHILHGE_01484	6.44e-145	arpJ	-	-	P	ko:K02029,ko:K02030	-	ko00000,ko00002,ko02000	ABC transporter permease
HOHILHGE_01485	1.67e-183	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Bacterial periplasmic substrate-binding proteins
HOHILHGE_01486	2.87e-10	emrE	-	-	U	ko:K03297,ko:K11741	-	ko00000,ko02000	PFAM small multidrug resistance protein
HOHILHGE_01487	8.21e-07	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_01489	1.47e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_01499	8.34e-101	-	-	-	-	-	-	-	-
HOHILHGE_01502	3.84e-51	-	-	-	S	-	-	-	Protein of unknown function (DUF1797)
HOHILHGE_01503	1.62e-230	mprF	-	-	I	ko:K07027	-	ko00000,ko02000	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOHILHGE_01504	1.28e-253	cpoA	2.4.1.208	GT4	M	ko:K13677,ko:K13678	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HOHILHGE_01505	3.25e-293	pimB	2.4.1.337	GT4	M	ko:K19002	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Glycosyltransferase, group 1 family protein
HOHILHGE_01506	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOHILHGE_01507	6.14e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPR
HOHILHGE_01508	2.41e-07	-	-	-	-	-	-	-	-
HOHILHGE_01509	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HOHILHGE_01510	2.91e-165	-	-	-	F	-	-	-	NUDIX domain
HOHILHGE_01511	5.82e-141	pncA	-	-	Q	-	-	-	Isochorismatase family
HOHILHGE_01512	0.0	nadC2	6.3.4.21	-	F	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HOHILHGE_01513	9.42e-125	-	-	-	S	-	-	-	Pfam:DUF3816
HOHILHGE_01514	3.86e-181	-	-	-	G	-	-	-	MucBP domain
HOHILHGE_01515	5.54e-172	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HOHILHGE_01516	1.81e-207	-	-	-	EG	-	-	-	EamA-like transporter family
HOHILHGE_01517	5.6e-314	yxbA	6.3.1.12	-	S	ko:K17810	-	ko00000,ko01000	ATP-grasp enzyme
HOHILHGE_01519	1.29e-198	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01520	2.08e-84	-	-	-	K	-	-	-	Transcriptional regulator, GntR family
HOHILHGE_01521	4.41e-218	rfbB	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HOHILHGE_01522	2.21e-100	-	-	-	S	-	-	-	Bacterial membrane protein, YfhO
HOHILHGE_01523	7.39e-127	-	-	-	S	ko:K07011	-	ko00000	Glycosyltransferase like family 2
HOHILHGE_01524	2.62e-119	-	-	-	M	-	-	-	transferase activity, transferring glycosyl groups
HOHILHGE_01525	0.0	prfC	-	-	J	ko:K02837	-	ko00000,ko03012	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HOHILHGE_01526	1.43e-208	ykoT	-	-	M	-	-	-	Glycosyl transferase family 2
HOHILHGE_01527	2.3e-215	yueF	-	-	S	-	-	-	AI-2E family transporter
HOHILHGE_01528	3.27e-204	yfdH	-	GT2	M	ko:K12999	-	ko00000,ko01000,ko01003,ko01005	Glycosyltransferase, group 2 family protein
HOHILHGE_01529	8.03e-10	-	-	-	-	-	-	-	-
HOHILHGE_01530	2.53e-115	-	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	NLP P60 protein
HOHILHGE_01531	1.86e-71	-	-	CBM50	NU	ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOHILHGE_01532	1.71e-86	csd1	3.5.1.28	-	M	ko:K01447,ko:K17733,ko:K19117	-	ko00000,ko01000,ko01002,ko01011,ko02048	N-Acetylmuramoyl-L-alanine amidase
HOHILHGE_01533	5.02e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01534	9.81e-257	cps1C	-	-	S	ko:K03328	-	ko00000	Membrane protein involved in the export of O-antigen and teichoic acid
HOHILHGE_01535	9.78e-281	glf	5.4.99.9	-	M	ko:K01854	ko00052,ko00520,map00052,map00520	ko00000,ko00001,ko01000	UDP-galactopyranose mutase
HOHILHGE_01536	5.6e-62	cps3I	-	-	G	-	-	-	Acyltransferase family
HOHILHGE_01537	4.2e-41	-	-	-	M	-	-	-	biosynthesis protein
HOHILHGE_01538	9.54e-117	cps3F	-	-	-	-	-	-	-
HOHILHGE_01539	4.7e-189	cps1D	-	-	M	-	-	-	Domain of unknown function (DUF4422)
HOHILHGE_01540	8.21e-151	rfbP	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	Bacterial sugar transferase
HOHILHGE_01541	1.61e-185	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Regulatory protein RecX
HOHILHGE_01543	4.37e-43	-	-	-	S	-	-	-	Protein of unknown function (DUF2922)
HOHILHGE_01544	5.86e-192	rbn	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HOHILHGE_01545	0.0	XK27_08315	-	-	M	-	-	-	Sulfatase
HOHILHGE_01546	2.04e-288	XK27_08315	-	-	M	-	-	-	Sulfatase
HOHILHGE_01547	1.18e-165	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_01548	4.75e-61	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01549	3.92e-213	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine Aminopeptidase
HOHILHGE_01550	6.75e-101	ykuP	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HOHILHGE_01551	1.38e-98	gtcA	-	-	S	-	-	-	Teichoic acid glycosylation protein
HOHILHGE_01553	2.35e-304	yfmL	-	-	L	-	-	-	DEAD DEAH box helicase
HOHILHGE_01554	7.01e-244	mocA	-	-	S	-	-	-	Oxidoreductase
HOHILHGE_01555	5.17e-83	-	-	-	S	-	-	-	Domain of unknown function (DUF4828)
HOHILHGE_01556	1.04e-133	-	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HOHILHGE_01557	1.51e-204	-	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily
HOHILHGE_01558	0.0	gshA	6.3.2.2	-	H	ko:K01919	ko00270,ko00480,ko01100,map00270,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the glutamate--cysteine ligase type 1 family
HOHILHGE_01559	3.67e-180	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOHILHGE_01560	4.1e-44	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HOHILHGE_01561	0.0	ykpA	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HOHILHGE_01562	2.41e-111	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HOHILHGE_01563	7.08e-133	-	-	-	-	-	-	-	-
HOHILHGE_01564	3.25e-275	brpA	-	-	K	-	-	-	Cell envelope-like function transcriptional attenuator common domain protein
HOHILHGE_01565	2.39e-131	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HOHILHGE_01566	4.01e-81	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOHILHGE_01567	4.81e-59	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HOHILHGE_01568	8.81e-129	ogt	2.1.1.63	-	L	ko:K00567	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HOHILHGE_01569	9.54e-134	-	-	-	S	-	-	-	CAAX protease self-immunity
HOHILHGE_01571	3.8e-31	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HOHILHGE_01572	1.79e-214	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01573	1.26e-147	-	-	-	Q	-	-	-	Methyltransferase domain
HOHILHGE_01574	6.76e-112	-	1.5.1.40	-	S	ko:K06988	-	ko00000,ko01000	NADP oxidoreductase coenzyme F420-dependent
HOHILHGE_01575	2.49e-65	-	-	-	K	-	-	-	2 iron, 2 sulfur cluster binding
HOHILHGE_01576	0.0	sufI	-	-	Q	-	-	-	Multicopper oxidase
HOHILHGE_01577	4.18e-111	-	-	-	S	ko:K19055	-	ko00000,ko01000,ko03016	Aminoacyl-tRNA editing domain
HOHILHGE_01578	1.32e-95	-	3.5.3.18	-	E	ko:K01482	-	ko00000,ko01000,ko04147	Amidinotransferase
HOHILHGE_01580	3.23e-242	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter NhaC
HOHILHGE_01581	1.42e-131	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HOHILHGE_01582	4.71e-36	-	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HOHILHGE_01584	2.37e-231	-	-	-	S	ko:K07035	-	ko00000	Phosphotransferase system, EIIC
HOHILHGE_01585	1.57e-32	-	-	-	D	ko:K19158	-	ko00000,ko01000,ko02048	mRNA cleavage
HOHILHGE_01586	9.21e-19	-	-	-	D	-	-	-	Antitoxin component of a toxin-antitoxin (TA) module
HOHILHGE_01587	2.94e-135	-	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HOHILHGE_01588	9.82e-156	ribB	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HOHILHGE_01590	1.39e-81	-	-	-	S	-	-	-	YjbR
HOHILHGE_01591	7.47e-148	-	-	-	S	ko:K07126	-	ko00000	Sel1-like repeats.
HOHILHGE_01592	4.88e-101	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01593	2.1e-269	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family
HOHILHGE_01594	4.75e-232	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	DegT/DnrJ/EryC1/StrS aminotransferase family
HOHILHGE_01595	7.74e-257	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HOHILHGE_01596	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	L-aspartate oxidase
HOHILHGE_01597	0.0	lacL	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	hydrolase activity, hydrolyzing O-glycosyl compounds
HOHILHGE_01598	2.24e-236	lacM	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase
HOHILHGE_01599	1.8e-50	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOHILHGE_01600	4.55e-162	melA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOHILHGE_01601	3.08e-286	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01603	2.53e-242	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_01604	2.21e-255	-	-	-	C	-	-	-	Belongs to the LDH2 MDH2 oxidoreductase family
HOHILHGE_01605	8.48e-241	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_01606	2.2e-221	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01607	5.25e-140	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
HOHILHGE_01608	2.48e-62	-	-	-	L	ko:K07483	-	ko00000	Transposase
HOHILHGE_01609	6.28e-218	-	-	-	L	ko:K07497	-	ko00000	Integrase core domain
HOHILHGE_01610	6.59e-140	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_01612	3.56e-255	-	2.1.1.72	-	L	ko:K07318	-	ko00000,ko01000,ko02048	D12 class N6 adenine-specific DNA methyltransferase
HOHILHGE_01614	3.2e-76	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01615	8.22e-197	-	-	-	L	-	-	-	Restriction endonuclease FokI, C terminal
HOHILHGE_01616	7.63e-124	-	2.1.1.72	-	L	ko:K06223	ko03430,map03430	ko00000,ko00001,ko01000,ko02048,ko03032,ko03400	DNA methyltransferase
HOHILHGE_01617	5.05e-84	-	-	-	S	-	-	-	AAA ATPase domain
HOHILHGE_01618	1.95e-33	-	-	-	S	-	-	-	AAA ATPase domain
HOHILHGE_01619	7.48e-38	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HOHILHGE_01620	8.31e-75	-	-	-	L	-	-	-	ATPase involved in DNA repair
HOHILHGE_01622	2.4e-19	-	-	-	-	-	-	-	-
HOHILHGE_01623	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01625	8.08e-95	-	-	-	K	-	-	-	DNA-templated transcription, initiation
HOHILHGE_01626	1.21e-36	-	-	-	-	-	-	-	-
HOHILHGE_01627	1.63e-62	-	-	-	-	-	-	-	-
HOHILHGE_01628	6.02e-269	-	-	-	L	-	-	-	Protein of unknown function (DUF2800)
HOHILHGE_01629	5.04e-124	-	-	-	S	-	-	-	Protein of unknown function (DUF2815)
HOHILHGE_01630	0.0	-	2.7.7.7	-	L	ko:K02334	-	ko00000,ko01000	DNA polymerase
HOHILHGE_01631	5.66e-79	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOHILHGE_01632	0.0	-	-	-	S	ko:K06919	-	ko00000	Phage plasmid primase, P4
HOHILHGE_01633	1.85e-54	-	-	-	S	-	-	-	VRR_NUC
HOHILHGE_01634	1.18e-307	-	-	-	L	-	-	-	SNF2 family N-terminal domain
HOHILHGE_01635	8.04e-101	-	-	-	-	-	-	-	-
HOHILHGE_01636	1.56e-126	-	-	-	-	-	-	-	-
HOHILHGE_01637	2.31e-292	-	-	-	KL	-	-	-	DNA methylase
HOHILHGE_01639	7.59e-101	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOHILHGE_01640	2.4e-41	-	-	-	S	-	-	-	Domain of unknown function (DUF5049)
HOHILHGE_01641	0.0	-	-	-	S	-	-	-	overlaps another CDS with the same product name
HOHILHGE_01642	6.35e-293	-	-	-	S	-	-	-	Phage portal protein
HOHILHGE_01643	2.85e-141	-	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S14 family
HOHILHGE_01644	7.85e-251	-	-	-	S	-	-	-	Phage capsid family
HOHILHGE_01645	5.76e-53	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HOHILHGE_01646	7.16e-79	-	-	-	S	-	-	-	Phage head-tail joining protein
HOHILHGE_01647	1.98e-81	-	-	-	S	-	-	-	Bacteriophage holin family
HOHILHGE_01648	1.49e-114	-	-	-	M	-	-	-	Glycosyl hydrolases family 25
HOHILHGE_01649	4.34e-41	-	-	-	-	-	-	-	-
HOHILHGE_01650	0.0	-	-	-	L	-	-	-	Recombinase zinc beta ribbon domain
HOHILHGE_01651	0.0	-	-	-	L	-	-	-	Recombinase
HOHILHGE_01652	5.77e-149	-	-	-	L	ko:K07448	-	ko00000,ko02048	Mrr N-terminal domain
HOHILHGE_01653	0.0	rumA_2	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HOHILHGE_01654	8.8e-238	dagK	2.7.1.107	-	G	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	Lipid kinase
HOHILHGE_01655	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOHILHGE_01656	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HOHILHGE_01657	4.92e-65	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HOHILHGE_01658	7.88e-233	camS	-	-	S	-	-	-	sex pheromone
HOHILHGE_01659	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HOHILHGE_01660	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HOHILHGE_01661	1.24e-278	purK2	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HOHILHGE_01662	9.17e-131	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HOHILHGE_01663	2.33e-142	acmA	3.2.1.17, 3.2.1.96	-	NU	ko:K01185,ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	mannosyl-glycoprotein
HOHILHGE_01664	8.64e-178	budC	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HOHILHGE_01665	1.6e-83	-	-	-	S	-	-	-	interspecies interaction between organisms
HOHILHGE_01666	3.28e-154	-	-	-	S	-	-	-	interspecies interaction between organisms
HOHILHGE_01667	2.78e-85	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HOHILHGE_01668	7.91e-104	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HOHILHGE_01669	8.08e-188	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HOHILHGE_01670	9.63e-178	ecfT	-	-	U	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOHILHGE_01671	5.6e-193	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HOHILHGE_01672	1.02e-80	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HOHILHGE_01673	1.41e-216	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOHILHGE_01674	8.02e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HOHILHGE_01675	1.32e-76	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOHILHGE_01676	6.38e-20	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HOHILHGE_01677	1.69e-45	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HOHILHGE_01678	2.16e-156	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HOHILHGE_01679	7.83e-301	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HOHILHGE_01680	3.5e-92	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to the 23S rRNA
HOHILHGE_01681	6.96e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HOHILHGE_01682	3.59e-113	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HOHILHGE_01683	5.55e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HOHILHGE_01684	2.05e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HOHILHGE_01685	7.64e-88	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HOHILHGE_01686	2.46e-40	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HOHILHGE_01687	1.75e-123	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOHILHGE_01688	1.28e-65	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HOHILHGE_01689	2.55e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HOHILHGE_01690	4.48e-55	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HOHILHGE_01691	1.35e-38	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HOHILHGE_01692	2.78e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HOHILHGE_01693	3.43e-156	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HOHILHGE_01694	2.63e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HOHILHGE_01695	1.51e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HOHILHGE_01696	3.32e-203	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOHILHGE_01697	2.76e-60	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HOHILHGE_01698	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HOHILHGE_01699	5.89e-153	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HOHILHGE_01700	3.14e-66	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HOHILHGE_01701	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HOHILHGE_01702	4.15e-108	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HOHILHGE_01703	3.58e-93	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HOHILHGE_01704	7.05e-40	pilD	3.4.23.43	-	NOU	ko:K02236,ko:K02506,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	aspartic-type endopeptidase activity
HOHILHGE_01705	1.18e-272	-	-	-	-	-	-	-	-
HOHILHGE_01706	2.92e-173	puuD	-	-	S	ko:K07010	-	ko00000,ko01002	peptidase C26
HOHILHGE_01707	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOHILHGE_01708	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HOHILHGE_01709	1.72e-136	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOHILHGE_01710	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HOHILHGE_01711	2.13e-101	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HOHILHGE_01712	6.91e-233	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_01713	5.56e-289	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01714	7.92e-247	adhP	1.1.1.1	-	C	ko:K00001,ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	alcohol dehydrogenase
HOHILHGE_01715	4.84e-170	XK27_07210	-	-	S	-	-	-	B3 4 domain
HOHILHGE_01716	1.49e-154	-	-	-	J	-	-	-	2'-5' RNA ligase superfamily
HOHILHGE_01717	4.19e-37	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Maltose acetyltransferase
HOHILHGE_01718	9.79e-96	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01719	2.05e-166	-	-	-	L	-	-	-	PFAM transposase, IS4 family protein
HOHILHGE_01720	1e-60	rmeB	-	-	K	-	-	-	transcriptional regulator, MerR family
HOHILHGE_01721	6.8e-93	thiW	-	-	S	-	-	-	Thiamine-precursor transporter protein (ThiW)
HOHILHGE_01722	1.09e-53	-	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HOHILHGE_01723	1.38e-188	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HOHILHGE_01724	2.51e-58	-	-	-	IQ	-	-	-	reductase
HOHILHGE_01725	5.16e-15	fabG1	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOHILHGE_01731	4.69e-151	dgk2	-	-	F	-	-	-	deoxynucleoside kinase
HOHILHGE_01732	0.0	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HOHILHGE_01734	4.9e-199	-	-	-	I	-	-	-	alpha/beta hydrolase fold
HOHILHGE_01735	2.11e-147	-	-	-	I	-	-	-	phosphatase
HOHILHGE_01736	8.17e-107	-	-	-	S	-	-	-	Threonine/Serine exporter, ThrE
HOHILHGE_01737	1.36e-161	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOHILHGE_01738	1.72e-40	cspC	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock protein
HOHILHGE_01739	2.06e-157	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	iron dependent repressor
HOHILHGE_01740	6.19e-209	-	-	-	P	ko:K16264	-	ko00000,ko02000	cation diffusion facilitator family transporter
HOHILHGE_01741	2e-145	-	-	-	S	-	-	-	membrane
HOHILHGE_01742	2.14e-138	-	-	-	S	-	-	-	VIT family
HOHILHGE_01743	1.68e-108	-	-	-	T	-	-	-	Belongs to the universal stress protein A family
HOHILHGE_01744	1.18e-28	elaA	-	-	S	ko:K02348	-	ko00000	acyltransferase COG2153
HOHILHGE_01745	1.08e-282	-	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HOHILHGE_01746	0.0	rnjA	-	-	J	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HOHILHGE_01747	7.8e-76	-	-	-	-	-	-	-	-
HOHILHGE_01748	1.62e-95	-	-	-	K	-	-	-	MerR HTH family regulatory protein
HOHILHGE_01749	0.0	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOHILHGE_01750	2.85e-151	-	-	-	S	-	-	-	Domain of unknown function (DUF4811)
HOHILHGE_01751	3.51e-187	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HOHILHGE_01752	4.76e-214	yjbO	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HOHILHGE_01754	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HOHILHGE_01755	2.36e-137	-	3.5.1.124	-	S	ko:K03152	-	ko00000,ko01000,ko01002	DJ-1/PfpI family
HOHILHGE_01756	3.88e-241	-	-	-	I	-	-	-	Alpha beta
HOHILHGE_01757	9.52e-286	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01758	7.77e-152	-	3.2.2.27	-	L	ko:K21929	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Uracil-DNA glycosylase
HOHILHGE_01759	0.0	-	-	-	S	-	-	-	Putative threonine/serine exporter
HOHILHGE_01760	1.12e-209	mleR2	-	-	K	-	-	-	LysR family transcriptional regulator
HOHILHGE_01761	2.67e-222	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01762	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_01763	6.7e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01764	3.49e-27	mleS	1.1.1.38, 4.1.1.101	-	C	ko:K00027,ko:K22212	ko00620,ko01120,ko01200,ko02020,map00620,map01120,map01200,map02020	ko00000,ko00001,ko01000	Malic enzyme
HOHILHGE_01765	1.27e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01766	3.79e-16	mleR	-	-	K	-	-	-	LysR family
HOHILHGE_01767	3.03e-26	mleR	-	-	K	-	-	-	LysR family
HOHILHGE_01768	2.2e-16	-	-	-	I	ko:K01066	-	ko00000,ko01000	COG0657 Esterase lipase
HOHILHGE_01770	1.87e-139	ppiB	5.2.1.8	-	G	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HOHILHGE_01771	0.0	scrA	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HOHILHGE_01772	2.26e-247	adh	1.1.1.1	-	C	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Zinc-binding alcohol dehydrogenase family protein
HOHILHGE_01773	0.0	scrB	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HOHILHGE_01774	0.0	-	-	-	S	ko:K13730	ko05100,map05100	ko00000,ko00001	Uncharacterized protein conserved in bacteria (DUF2252)
HOHILHGE_01775	1.71e-211	-	-	-	K	-	-	-	LysR substrate binding domain
HOHILHGE_01776	4.52e-211	-	-	-	S	-	-	-	Polyphosphate nucleotide phosphotransferase, PPK2 family
HOHILHGE_01777	5.32e-142	-	-	-	-	-	-	-	-
HOHILHGE_01779	3.03e-125	potE	-	-	E	-	-	-	Amino Acid
HOHILHGE_01780	8.12e-200	potE	-	-	E	-	-	-	Amino Acid
HOHILHGE_01781	8.88e-216	-	-	-	V	-	-	-	Beta-lactamase enzyme family
HOHILHGE_01782	1.21e-285	dacA	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HOHILHGE_01783	1.28e-126	-	-	-	-	-	-	-	-
HOHILHGE_01784	1.74e-252	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Lactonase, 7-bladed beta-propeller
HOHILHGE_01785	1.47e-136	-	-	-	I	-	-	-	PAP2 superfamily
HOHILHGE_01786	1.32e-70	-	-	-	S	-	-	-	MazG-like family
HOHILHGE_01787	0.0	-	-	-	L	-	-	-	Helicase C-terminal domain protein
HOHILHGE_01788	4.51e-92	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	NUDIX domain
HOHILHGE_01789	8.98e-122	-	-	-	K	-	-	-	transcriptional regulator
HOHILHGE_01790	3.59e-35	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOHILHGE_01791	1.14e-38	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOHILHGE_01792	2.23e-200	ycnB	-	-	U	-	-	-	Belongs to the major facilitator superfamily
HOHILHGE_01795	8.11e-52	-	-	-	S	-	-	-	Cytochrome B5
HOHILHGE_01796	1.62e-115	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOHILHGE_01797	1.74e-273	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	methionine synthase, vitamin-B12 independent
HOHILHGE_01798	8.61e-22	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HOHILHGE_01799	5.59e-250	asnA	6.3.1.1	-	F	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	ko00000,ko00001,ko01000	aspartate--ammonia ligase
HOHILHGE_01800	9.52e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01801	5.56e-19	-	-	-	NU	-	-	-	mannosyl-glycoprotein
HOHILHGE_01802	2.33e-120	-	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HOHILHGE_01803	0.0	umuC	-	-	L	ko:K03502	-	ko00000,ko03400	impB/mucB/samB family C-terminal domain
HOHILHGE_01804	5.95e-106	-	-	-	S	-	-	-	Psort location Cytoplasmic, score
HOHILHGE_01805	5.78e-14	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOHILHGE_01806	1.95e-290	-	-	-	L	-	-	-	MULE transposase domain
HOHILHGE_01807	5.17e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01808	8.24e-61	-	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HOHILHGE_01809	2.1e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HOHILHGE_01810	2.35e-243	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HOHILHGE_01811	1.59e-86	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HOHILHGE_01812	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Acetyl-CoA carboxylase biotin carboxylase subunit
HOHILHGE_01813	4.11e-172	-	-	-	S	ko:K07160	-	ko00000	LamB/YcsF family
HOHILHGE_01814	1e-270	ycsG	-	-	P	-	-	-	Natural resistance-associated macrophage protein
HOHILHGE_01815	5.01e-189	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_01816	6.71e-47	-	-	-	EGP	-	-	-	Major Facilitator
HOHILHGE_01817	0.0	-	1.8.1.7	-	C	ko:K00383	ko00480,ko04918,map00480,map04918	ko00000,ko00001,ko01000	pyridine nucleotide-disulfide oxidoreductase
HOHILHGE_01818	3.23e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOHILHGE_01819	7.51e-193	-	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HOHILHGE_01821	0.0	gabT	2.6.1.19, 5.1.1.21	-	E	ko:K00823,ko:K20708	ko00250,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HOHILHGE_01822	0.0	ctrA	-	-	E	ko:K03294	-	ko00000	amino acid
HOHILHGE_01823	1.23e-105	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOHILHGE_01824	9.92e-10	-	-	-	S	-	-	-	NADPH-dependent FMN reductase
HOHILHGE_01825	8.79e-201	yneP	-	-	L	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HOHILHGE_01826	1.87e-39	-	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	Hexapeptide repeat of succinyl-transferase
HOHILHGE_01827	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HOHILHGE_01828	4.82e-303	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HOHILHGE_01829	0.0	-	-	-	M	-	-	-	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HOHILHGE_01830	7.76e-41	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_01831	7.21e-15	-	1.3.1.9	-	S	ko:K02371	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Nitronate monooxygenase
HOHILHGE_01832	7.84e-71	-	-	-	K	-	-	-	Helix-turn-helix domain
HOHILHGE_01833	4.09e-136	-	-	-	S	-	-	-	Domain of unknown function (DUF4767)
HOHILHGE_01834	6.5e-10	-	-	-	-	-	-	-	-
HOHILHGE_01835	9.52e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01836	6.52e-17	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_01837	5.87e-51	-	-	-	L	ko:K07483	-	ko00000	Transposase and inactivated derivatives
HOHILHGE_01838	2.07e-85	is18	-	-	L	-	-	-	Integrase core domain
HOHILHGE_01839	1.64e-67	is18	-	-	L	-	-	-	COG2801 Transposase and inactivated derivatives
HOHILHGE_01840	2.64e-287	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01841	4.68e-119	ram2	3.2.1.40	-	G	ko:K05989	-	ko00000,ko01000	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HOHILHGE_01842	5.55e-127	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HOHILHGE_01843	1.39e-28	-	-	-	T	-	-	-	Region found in RelA / SpoT proteins
HOHILHGE_01844	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HOHILHGE_01845	7.54e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01846	7.31e-133	dar	1.1.1.304, 1.1.1.76	-	IQ	ko:K03366	ko00650,map00650	ko00000,ko00001,ko01000	reductase
HOHILHGE_01847	4.13e-104	luxS	4.4.1.21	-	H	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HOHILHGE_01848	2.13e-165	metQ1	-	-	P	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HOHILHGE_01849	2.31e-120	metI	-	-	P	ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter permease
HOHILHGE_01850	7.97e-166	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HOHILHGE_01853	7.76e-100	dltr	-	-	K	-	-	-	response regulator
HOHILHGE_01854	4.79e-12	sptS	-	-	T	-	-	-	Histidine kinase
HOHILHGE_01855	1.15e-119	sptS	-	-	T	-	-	-	Histidine kinase
HOHILHGE_01856	1.61e-223	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HOHILHGE_01857	7.5e-95	-	-	-	K	-	-	-	acetyltransferase
HOHILHGE_01858	4.29e-174	-	-	-	IQ	-	-	-	dehydrogenase reductase
HOHILHGE_01859	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HOHILHGE_01860	1.58e-203	-	-	-	EG	-	-	-	EamA-like transporter family
HOHILHGE_01861	9.06e-125	-	-	-	L	ko:K07483,ko:K09936	ko02024,map02024	ko00000,ko00001,ko02000	Helix-turn-helix domain
HOHILHGE_01862	1.79e-214	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01863	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HOHILHGE_01864	1.45e-152	-	-	-	S	ko:K03975	-	ko00000	SNARE associated Golgi protein
HOHILHGE_01865	1.92e-155	pgm3	-	-	G	-	-	-	phosphoglycerate mutase
HOHILHGE_01866	1.69e-296	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HOHILHGE_01867	1.22e-141	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HOHILHGE_01868	1.99e-103	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HOHILHGE_01869	2.05e-172	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HOHILHGE_01870	0.0	-	-	-	E	-	-	-	amino acid
HOHILHGE_01871	9.24e-114	-	-	-	K	-	-	-	FR47-like protein
HOHILHGE_01872	1.85e-179	-	-	-	L	-	-	-	PFAM Integrase catalytic region
HOHILHGE_01873	6.65e-309	yhgE	-	-	V	ko:K01421	-	ko00000	domain protein
HOHILHGE_01874	9.96e-121	-	-	-	K	-	-	-	Transcriptional regulator (TetR family)
HOHILHGE_01875	3.24e-250	galM	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of alpha and beta anomers of maltose
HOHILHGE_01876	9.59e-215	-	-	-	-	-	-	-	-
HOHILHGE_01877	4.69e-10	-	3.2.1.14	GH18	-	ko:K01183	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	-
HOHILHGE_01878	7.28e-110	zur	-	-	P	ko:K02076,ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HOHILHGE_01879	1.36e-136	gmk2	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Guanylate kinase
HOHILHGE_01880	3.66e-94	-	-	-	F	-	-	-	Nudix hydrolase
HOHILHGE_01881	2.83e-260	yhdG	-	-	E	ko:K03294	-	ko00000	Amino Acid
HOHILHGE_01882	9.52e-303	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01883	1.03e-105	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_01884	0.0	pepX	3.4.14.11	-	E	ko:K01281	-	ko00000,ko01000,ko01002	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HOHILHGE_01885	2.25e-226	-	3.4.11.5	-	E	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Releases the N-terminal proline from various substrates
HOHILHGE_01886	5.93e-149	-	-	-	S	-	-	-	HAD hydrolase, family IA, variant
HOHILHGE_01887	0.0	-	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2325)
HOHILHGE_01888	8.41e-235	-	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HOHILHGE_01889	9.26e-218	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Ribonucleotide reductase, small chain
HOHILHGE_01890	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HOHILHGE_01891	1.64e-108	nrdI	-	-	F	ko:K03647	-	ko00000	NrdI Flavodoxin like
HOHILHGE_01892	8.3e-141	yciB	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HOHILHGE_01893	3.17e-260	yngD	-	-	S	ko:K07097	-	ko00000	DHHA1 domain
HOHILHGE_01894	0.0	-	-	-	S	-	-	-	ABC transporter, ATP-binding protein
HOHILHGE_01895	3.13e-228	ABC-SBP	-	-	S	ko:K01989	-	ko00000,ko00002,ko02000	ABC transporter
HOHILHGE_01896	3.09e-192	XK27_08840	-	-	U	ko:K05832	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HOHILHGE_01897	1.32e-170	XK27_08845	-	-	S	ko:K05833	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01899	6.23e-286	amt	-	-	P	ko:K03320	-	ko00000,ko02000	ammonium transporter
HOHILHGE_01900	4.32e-297	mepA	-	-	V	ko:K18908	-	ko00000,ko00002,ko01504,ko02000	MATE efflux family protein
HOHILHGE_01901	5.58e-217	scrK	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	ROK family
HOHILHGE_01902	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HOHILHGE_01903	4e-234	fruR3	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOHILHGE_01904	5.72e-206	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	Dehydrogenase
HOHILHGE_01905	1.72e-213	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOHILHGE_01906	8.69e-281	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_01907	5.92e-58	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
HOHILHGE_01908	1.89e-149	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01909	8.45e-75	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HOHILHGE_01910	3.93e-180	yceF	-	-	P	ko:K05794	-	ko00000	membrane
HOHILHGE_01911	5.56e-213	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HOHILHGE_01912	1.6e-218	corA	-	-	P	ko:K03284	-	ko00000,ko02000	CorA-like Mg2+ transporter protein
HOHILHGE_01913	5.59e-308	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_01914	4.34e-299	pbuX	-	-	F	ko:K03458,ko:K16169	-	ko00000,ko02000	xanthine permease
HOHILHGE_01915	4.57e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_01916	3.09e-17	-	-	-	L	ko:K07483	-	ko00000	Helix-turn-helix domain
HOHILHGE_01917	5.85e-192	qorB	1.6.5.2	-	GM	ko:K19267	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	NmrA-like family
HOHILHGE_01918	3.31e-162	pgm3	-	-	G	-	-	-	phosphoglycerate mutase family
HOHILHGE_01919	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HOHILHGE_01920	4.34e-109	-	-	-	-	-	-	-	-
HOHILHGE_01921	1.41e-239	-	-	-	L	ko:K07482	-	ko00000	Helix-turn-helix domain
HOHILHGE_01922	6.32e-141	flp	-	-	K	ko:K21562	-	ko00000,ko03000	helix_turn_helix, cAMP Regulatory protein
HOHILHGE_01923	6.6e-129	dpsB	-	-	P	-	-	-	Belongs to the Dps family
HOHILHGE_01924	9.17e-45	copZ	-	-	P	-	-	-	Heavy-metal-associated domain
HOHILHGE_01925	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	P-type ATPase
HOHILHGE_01926	1.51e-235	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HOHILHGE_01927	3.41e-231	iunH1	3.2.2.1	-	F	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	ko00000,ko00001,ko01000	nucleoside hydrolase
HOHILHGE_01928	1.66e-130	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HOHILHGE_01929	0.0	-	-	-	S	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01930	3.54e-148	-	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HOHILHGE_01931	6.26e-23	-	-	-	-	-	-	-	-
HOHILHGE_01932	0.0	nhaK	-	-	P	ko:K03316	-	ko00000	Sodium proton antiporter
HOHILHGE_01933	8.85e-243	lplL	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Bacterial lipoate protein ligase C-terminus
HOHILHGE_01934	9.46e-96	-	-	-	O	-	-	-	OsmC-like protein
HOHILHGE_01935	9.85e-236	ybcH	-	-	D	ko:K06889	-	ko00000	Alpha beta
HOHILHGE_01936	2.22e-98	-	-	-	K	-	-	-	Transcriptional regulator
HOHILHGE_01937	8.75e-200	-	-	-	-	-	-	-	-
HOHILHGE_01938	7.95e-12	-	-	-	-	-	-	-	-
HOHILHGE_01939	1.79e-77	-	-	-	-	-	-	-	-
HOHILHGE_01940	2.16e-98	uspA3	-	-	T	-	-	-	universal stress protein
HOHILHGE_01942	3.45e-175	hflC	-	-	O	ko:K04087	-	ko00000,ko00002,ko01000	prohibitin homologues
HOHILHGE_01943	9.06e-313	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	Major Facilitator Superfamily
HOHILHGE_01944	0.0	tkt	2.2.1.1	-	H	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HOHILHGE_01945	4.63e-173	tal	2.2.1.2	-	H	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase/Fructose-6-phosphate aldolase
HOHILHGE_01946	1.5e-158	rpiA	5.3.1.6	-	G	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HOHILHGE_01947	8.17e-98	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01948	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HOHILHGE_01949	6.31e-26	fucP	-	-	G	ko:K02429	-	ko00000,ko02000	Major Facilitator Superfamily
HOHILHGE_01950	7.37e-224	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HOHILHGE_01951	0.0	-	-	-	G	ko:K02775	ko00052,ko01100,ko02060,map00052,map01100,map02060	ko00000,ko00001,ko00002,ko02000	PTS system Galactitol-specific IIC component
HOHILHGE_01952	1.19e-87	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HOHILHGE_01953	4.15e-135	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HOHILHGE_01954	0.0	potE	-	-	E	-	-	-	Amino Acid
HOHILHGE_01955	1.76e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01957	0.0	xfp	4.1.2.22, 4.1.2.9	-	G	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	ko00000,ko00001,ko01000	Phosphoketolase
HOHILHGE_01958	1.05e-182	-	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HOHILHGE_01959	8.99e-168	gntR	-	-	K	-	-	-	UbiC transcription regulator-associated domain protein
HOHILHGE_01960	4.23e-115	ebsC	-	-	J	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HOHILHGE_01961	1.8e-165	-	-	-	-	-	-	-	-
HOHILHGE_01962	0.0	pepD2	-	-	E	ko:K08659	-	ko00000,ko01000,ko01002	Dipeptidase
HOHILHGE_01963	4.35e-198	-	-	-	G	-	-	-	Xylose isomerase domain protein TIM barrel
HOHILHGE_01964	5.69e-111	-	-	-	K	-	-	-	Domain of unknown function (DUF1836)
HOHILHGE_01965	3.54e-116	-	-	-	GM	-	-	-	epimerase
HOHILHGE_01966	0.0	yhdP	-	-	S	-	-	-	Transporter associated domain
HOHILHGE_01967	1.24e-108	nrdI	-	-	F	ko:K03647	-	ko00000	Belongs to the NrdI family
HOHILHGE_01968	1.81e-98	-	-	-	S	ko:K04750	-	ko00000	3-demethylubiquinone-9 3-methyltransferase
HOHILHGE_01969	5.17e-220	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01970	8.11e-263	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	Transporter, major facilitator family protein
HOHILHGE_01971	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HOHILHGE_01972	0.0	gnd	1.1.1.343, 1.1.1.44	-	H	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HOHILHGE_01973	6.11e-106	usp5	-	-	T	-	-	-	universal stress protein
HOHILHGE_01974	3.07e-103	-	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	AsnC family
HOHILHGE_01975	7.6e-65	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOHILHGE_01976	1.62e-82	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HOHILHGE_01977	1.36e-98	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HOHILHGE_01978	1.72e-83	-	-	-	K	ko:K02525	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HOHILHGE_01979	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HOHILHGE_01980	2.61e-298	gltT	-	-	U	ko:K03309,ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HOHILHGE_01981	6.15e-161	-	-	-	S	-	-	-	Membrane
HOHILHGE_01982	0.0	lacS	-	-	G	ko:K11104,ko:K16209	-	ko00000,ko02000	Transporter
HOHILHGE_01983	0.0	rafA	3.2.1.22	-	G	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	alpha-galactosidase
HOHILHGE_01984	1.76e-99	-	-	-	L	-	-	-	Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HOHILHGE_01985	1.18e-229	galR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HOHILHGE_01986	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HOHILHGE_01987	1.71e-284	galK	2.7.1.6	-	F	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HOHILHGE_01988	6.63e-232	celE3	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase family
HOHILHGE_01989	1.26e-85	-	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Tyrosine phosphatase family
HOHILHGE_01990	2.44e-125	-	-	-	S	ko:K06910	-	ko00000	Phosphatidylethanolamine-binding protein
HOHILHGE_01991	1.21e-48	-	-	-	-	-	-	-	-
HOHILHGE_01992	4.14e-174	-	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_01993	4.27e-155	-	-	-	U	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HOHILHGE_01994	1.09e-180	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HOHILHGE_01995	9.08e-71	-	-	-	-	-	-	-	-
HOHILHGE_01996	1.65e-214	-	1.1.1.399, 1.1.1.95	-	CH	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HOHILHGE_01997	2.88e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HOHILHGE_01998	8.41e-186	pnuC	-	-	H	ko:K03811	-	ko00000,ko02000	nicotinamide mononucleotide transporter
HOHILHGE_01999	2.74e-117	ymdB	-	-	S	-	-	-	Macro domain protein
HOHILHGE_02000	0.0	pepO	-	-	O	ko:K07386	-	ko00000,ko01000,ko01002	Peptidase family M13
HOHILHGE_02001	1.73e-290	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HOHILHGE_02002	5.69e-53	-	-	-	-	-	-	-	-
HOHILHGE_02003	6.87e-268	-	-	-	S	-	-	-	Putative metallopeptidase domain
HOHILHGE_02004	6.68e-262	-	-	-	S	-	-	-	associated with various cellular activities
HOHILHGE_02005	4.71e-149	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HOHILHGE_02006	1.36e-85	yeaO	-	-	S	-	-	-	Protein of unknown function, DUF488
HOHILHGE_02008	2.32e-161	yrkL	-	-	S	-	-	-	Flavodoxin-like fold
HOHILHGE_02009	8.76e-73	-	-	-	-	-	-	-	-
HOHILHGE_02010	1.76e-139	nnrE	5.1.99.6	-	H	ko:K17759	-	ko00000,ko01000	Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HOHILHGE_02011	6.55e-126	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HOHILHGE_02012	1.68e-138	-	-	-	-	-	-	-	-
HOHILHGE_02013	1.11e-35	-	-	-	-	-	-	-	-
HOHILHGE_02014	1.11e-95	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOHILHGE_02015	6.82e-103	scrR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	Transcriptional regulator, LacI family
HOHILHGE_02016	1.63e-311	-	3.2.1.17	CBM50	NU	ko:K01185,ko:K02395,ko:K19223	-	ko00000,ko01000,ko01002,ko01011,ko02035	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HOHILHGE_02017	1.22e-86	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_02018	5.33e-199	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_02019	1.45e-60	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	Transcriptional regulator, ArsR family
HOHILHGE_02020	1.24e-98	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HOHILHGE_02021	2.78e-156	lolD	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HOHILHGE_02022	4.71e-208	yxeA	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter permease
HOHILHGE_02023	3.73e-137	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HOHILHGE_02024	4.04e-111	-	-	-	E	-	-	-	Zinc-binding dehydrogenase
HOHILHGE_02025	2e-304	-	-	-	L	ko:K07496	-	ko00000	transposase, IS605 OrfB family
HOHILHGE_02026	2.26e-288	B4168_4126	-	-	L	ko:K07493	-	ko00000	Transposase
HOHILHGE_02027	6.08e-312	tnpA1	-	-	L	-	-	-	PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HOHILHGE_02028	0.0	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HOHILHGE_02029	1.56e-62	-	-	-	-	-	-	-	-
HOHILHGE_02030	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HOHILHGE_02031	3.12e-63	-	-	-	L	-	-	-	nuclease
HOHILHGE_02032	8.47e-207	-	-	-	F	ko:K15051	-	ko00000	DNA/RNA non-specific endonuclease
HOHILHGE_02033	1.14e-145	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HOHILHGE_02034	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOHILHGE_02035	0.0	murE	6.3.2.13, 6.3.2.7	-	M	ko:K01928,ko:K05362	ko00300,ko00550,ko01100,map00300,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HOHILHGE_02036	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HOHILHGE_02037	1.25e-283	lysP	-	-	E	ko:K03293,ko:K11733	-	ko00000,ko02000	amino acid
HOHILHGE_02038	1.03e-75	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HOHILHGE_02039	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HOHILHGE_02040	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HOHILHGE_02041	4.65e-184	jag	-	-	S	ko:K06346	-	ko00000	R3H domain protein
HOHILHGE_02042	1.43e-186	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOHILHGE_02043	5.32e-75	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HOHILHGE_02044	7.96e-21	rpmH	-	-	J	ko:K02914	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL34 family