ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
HLLBMAHE_00001 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HLLBMAHE_00002 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HLLBMAHE_00003 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
HLLBMAHE_00004 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HLLBMAHE_00005 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
HLLBMAHE_00006 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLLBMAHE_00007 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HLLBMAHE_00008 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00011 7.47e-233 yaaC - - S - - - YaaC-like Protein
HLLBMAHE_00012 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HLLBMAHE_00013 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLLBMAHE_00014 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HLLBMAHE_00015 9.58e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HLLBMAHE_00016 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HLLBMAHE_00018 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
HLLBMAHE_00019 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
HLLBMAHE_00020 4.25e-275 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
HLLBMAHE_00021 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
HLLBMAHE_00022 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HLLBMAHE_00023 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLLBMAHE_00024 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HLLBMAHE_00025 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HLLBMAHE_00026 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
HLLBMAHE_00027 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
HLLBMAHE_00028 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00031 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
HLLBMAHE_00032 2.58e-130 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HLLBMAHE_00033 8.37e-259 yaaN - - P - - - Belongs to the TelA family
HLLBMAHE_00034 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
HLLBMAHE_00035 2.82e-147 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HLLBMAHE_00036 5.88e-72 yaaQ - - S - - - protein conserved in bacteria
HLLBMAHE_00037 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
HLLBMAHE_00038 6.64e-234 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
HLLBMAHE_00039 5.2e-188 yaaT - - S - - - stage 0 sporulation protein
HLLBMAHE_00040 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
HLLBMAHE_00041 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
HLLBMAHE_00042 4.19e-65 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
HLLBMAHE_00043 7.26e-208 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HLLBMAHE_00044 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
HLLBMAHE_00045 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HLLBMAHE_00046 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
HLLBMAHE_00047 1.91e-283 yabE - - T - - - protein conserved in bacteria
HLLBMAHE_00048 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HLLBMAHE_00049 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HLLBMAHE_00050 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
HLLBMAHE_00051 5.32e-53 veg - - S - - - protein conserved in bacteria
HLLBMAHE_00052 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
HLLBMAHE_00053 2.34e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HLLBMAHE_00054 4.66e-196 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
HLLBMAHE_00055 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
HLLBMAHE_00056 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HLLBMAHE_00057 4.27e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HLLBMAHE_00058 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HLLBMAHE_00059 2.77e-125 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HLLBMAHE_00060 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HLLBMAHE_00061 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
HLLBMAHE_00062 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HLLBMAHE_00063 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
HLLBMAHE_00064 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLLBMAHE_00065 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HLLBMAHE_00066 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HLLBMAHE_00067 1.91e-66 yabP - - S - - - Sporulation protein YabP
HLLBMAHE_00068 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
HLLBMAHE_00069 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
HLLBMAHE_00070 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HLLBMAHE_00073 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
HLLBMAHE_00074 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HLLBMAHE_00075 6.92e-236 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
HLLBMAHE_00076 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HLLBMAHE_00077 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
HLLBMAHE_00078 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HLLBMAHE_00079 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HLLBMAHE_00080 7.84e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HLLBMAHE_00081 5.93e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
HLLBMAHE_00082 3.62e-216 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HLLBMAHE_00083 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLLBMAHE_00084 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
HLLBMAHE_00085 8.89e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
HLLBMAHE_00086 7.82e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HLLBMAHE_00087 1.09e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HLLBMAHE_00088 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HLLBMAHE_00089 1.81e-41 yazB - - K - - - transcriptional
HLLBMAHE_00090 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLLBMAHE_00091 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
HLLBMAHE_00092 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00102 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00103 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
HLLBMAHE_00104 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
HLLBMAHE_00105 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HLLBMAHE_00106 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
HLLBMAHE_00107 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HLLBMAHE_00108 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HLLBMAHE_00109 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
HLLBMAHE_00110 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HLLBMAHE_00111 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HLLBMAHE_00112 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HLLBMAHE_00113 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
HLLBMAHE_00114 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
HLLBMAHE_00115 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HLLBMAHE_00116 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLLBMAHE_00117 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
HLLBMAHE_00118 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
HLLBMAHE_00119 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HLLBMAHE_00120 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
HLLBMAHE_00121 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HLLBMAHE_00122 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HLLBMAHE_00123 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HLLBMAHE_00124 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HLLBMAHE_00125 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
HLLBMAHE_00126 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLLBMAHE_00127 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLLBMAHE_00128 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
HLLBMAHE_00129 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HLLBMAHE_00130 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HLLBMAHE_00131 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HLLBMAHE_00132 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HLLBMAHE_00133 1.83e-230 ybaC - - S - - - Alpha/beta hydrolase family
HLLBMAHE_00134 2.13e-64 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
HLLBMAHE_00135 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HLLBMAHE_00136 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
HLLBMAHE_00137 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HLLBMAHE_00138 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HLLBMAHE_00139 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HLLBMAHE_00140 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HLLBMAHE_00141 6.89e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HLLBMAHE_00142 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HLLBMAHE_00143 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
HLLBMAHE_00144 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HLLBMAHE_00145 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HLLBMAHE_00146 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HLLBMAHE_00147 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HLLBMAHE_00148 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLLBMAHE_00149 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HLLBMAHE_00150 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HLLBMAHE_00151 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HLLBMAHE_00152 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HLLBMAHE_00153 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
HLLBMAHE_00154 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HLLBMAHE_00155 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HLLBMAHE_00156 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HLLBMAHE_00157 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HLLBMAHE_00158 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HLLBMAHE_00159 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
HLLBMAHE_00160 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HLLBMAHE_00161 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HLLBMAHE_00162 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HLLBMAHE_00163 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
HLLBMAHE_00164 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLLBMAHE_00165 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLLBMAHE_00166 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HLLBMAHE_00167 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HLLBMAHE_00168 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HLLBMAHE_00169 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
HLLBMAHE_00170 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
HLLBMAHE_00171 5.12e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
HLLBMAHE_00172 9.05e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HLLBMAHE_00173 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HLLBMAHE_00174 1.04e-122 gerD - - - ko:K06294 - ko00000 -
HLLBMAHE_00175 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
HLLBMAHE_00176 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
HLLBMAHE_00177 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00184 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00185 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00186 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HLLBMAHE_00187 4.71e-203 ybaS - - S - - - Na -dependent transporter
HLLBMAHE_00188 7.04e-73 ybbA - - S ko:K07017 - ko00000 Putative esterase
HLLBMAHE_00189 3.63e-152 yokD 2.3.1.81 - V ko:K00662 - ko00000,ko01000,ko01504 aminoglycoside
HLLBMAHE_00190 4.86e-31 - - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding proteins, family 5 Middle
HLLBMAHE_00191 1.31e-61 thiF 2.7.7.73 - H ko:K03148 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 ThiF family
HLLBMAHE_00192 0.000151 pstB1 - - V ko:K01990,ko:K02003,ko:K02068,ko:K05685 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 lipoprotein transporter activity
HLLBMAHE_00193 4.03e-76 - - - S - - - Major Facilitator Superfamily
HLLBMAHE_00194 3.3e-35 - - - BT - - - Cupin-like domain
HLLBMAHE_00195 1.01e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_00196 2.37e-225 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_00197 5.12e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
HLLBMAHE_00198 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
HLLBMAHE_00199 1.64e-302 ybbC - - S - - - protein conserved in bacteria
HLLBMAHE_00200 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
HLLBMAHE_00201 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
HLLBMAHE_00202 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_00203 3.14e-193 ybbH - - K - - - transcriptional
HLLBMAHE_00204 5.5e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HLLBMAHE_00205 3.13e-114 ybbJ - - J - - - acetyltransferase
HLLBMAHE_00206 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
HLLBMAHE_00212 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_00213 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HLLBMAHE_00214 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLLBMAHE_00215 1.6e-287 ybbR - - S - - - protein conserved in bacteria
HLLBMAHE_00216 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HLLBMAHE_00217 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HLLBMAHE_00218 5.87e-54 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLLBMAHE_00219 9.34e-128 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLLBMAHE_00220 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
HLLBMAHE_00221 1.29e-129 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLLBMAHE_00222 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLLBMAHE_00223 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
HLLBMAHE_00224 7.77e-120 ybcF - - P - - - carbonic anhydrase
HLLBMAHE_00226 4.6e-63 - - - - - - - -
HLLBMAHE_00227 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
HLLBMAHE_00228 1.79e-64 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
HLLBMAHE_00229 4.31e-182 - - - T - - - His Kinase A (phospho-acceptor) domain
HLLBMAHE_00231 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
HLLBMAHE_00232 1.49e-192 ybdN - - - - - - -
HLLBMAHE_00233 8.37e-206 ybdO - - S - - - Domain of unknown function (DUF4885)
HLLBMAHE_00234 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_00235 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
HLLBMAHE_00236 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
HLLBMAHE_00237 2.06e-190 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
HLLBMAHE_00238 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
HLLBMAHE_00239 1.28e-37 ybyB - - - - - - -
HLLBMAHE_00240 0.0 ybeC - - E - - - amino acid
HLLBMAHE_00241 1.11e-207 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
HLLBMAHE_00242 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
HLLBMAHE_00243 1.02e-46 - - - S - - - Protein of unknown function (DUF2651)
HLLBMAHE_00244 1.85e-212 ybfA - - K - - - FR47-like protein
HLLBMAHE_00245 1.3e-284 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_00247 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_00249 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
HLLBMAHE_00250 1.06e-207 ybfH - - EG - - - EamA-like transporter family
HLLBMAHE_00251 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
HLLBMAHE_00252 3.63e-43 - - - K - - - sigma factor activity
HLLBMAHE_00253 2.73e-28 xhlB - - S - - - SPP1 phage holin
HLLBMAHE_00254 4.52e-206 - - GH19 M ko:K03791 - ko00000 Lysin motif
HLLBMAHE_00255 2.61e-73 - - - - - - - -
HLLBMAHE_00256 1.54e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HLLBMAHE_00257 9.75e-228 mpr - - M - - - Belongs to the peptidase S1B family
HLLBMAHE_00259 2.96e-209 - - - S - - - Alpha/beta hydrolase family
HLLBMAHE_00260 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLLBMAHE_00261 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
HLLBMAHE_00262 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HLLBMAHE_00263 5.51e-60 ybfN - - - - - - -
HLLBMAHE_00265 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
HLLBMAHE_00266 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLLBMAHE_00267 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_00268 4.29e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLLBMAHE_00269 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HLLBMAHE_00271 3.29e-259 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HLLBMAHE_00272 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HLLBMAHE_00273 1.06e-232 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
HLLBMAHE_00275 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HLLBMAHE_00276 8.24e-191 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HLLBMAHE_00277 1.36e-15 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HLLBMAHE_00278 3.4e-292 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_00279 1.58e-213 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
HLLBMAHE_00280 5.3e-206 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
HLLBMAHE_00281 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLLBMAHE_00282 7.31e-316 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_00283 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HLLBMAHE_00284 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
HLLBMAHE_00285 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HLLBMAHE_00286 1.34e-121 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HLLBMAHE_00287 1.92e-67 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
HLLBMAHE_00288 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
HLLBMAHE_00289 2.44e-216 eamA1 - - EG - - - spore germination
HLLBMAHE_00290 9.12e-161 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_00291 6.48e-216 ycbM - - T - - - Histidine kinase
HLLBMAHE_00292 1.12e-214 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_00293 4.75e-147 - - - S - - - ABC-2 family transporter protein
HLLBMAHE_00294 2.48e-73 ycbP - - S - - - Protein of unknown function (DUF2512)
HLLBMAHE_00295 6.1e-101 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HLLBMAHE_00296 6.36e-173 ycbR - - T - - - vWA found in TerF C terminus
HLLBMAHE_00297 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
HLLBMAHE_00298 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLLBMAHE_00299 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLLBMAHE_00300 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HLLBMAHE_00301 4.66e-257 ycbU - - E - - - Selenocysteine lyase
HLLBMAHE_00302 2.39e-300 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
HLLBMAHE_00303 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HLLBMAHE_00304 8.37e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HLLBMAHE_00306 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_00307 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLLBMAHE_00308 4.32e-78 - - - S - - - RDD family
HLLBMAHE_00309 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
HLLBMAHE_00310 1.25e-212 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
HLLBMAHE_00311 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HLLBMAHE_00312 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HLLBMAHE_00313 5.64e-257 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_00314 2.9e-28 yccK - - C - - - Aldo keto reductase
HLLBMAHE_00315 1.29e-182 yccK - - C - - - Aldo keto reductase
HLLBMAHE_00316 3.18e-240 ycdA - - S - - - Domain of unknown function (DUF5105)
HLLBMAHE_00317 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_00318 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_00319 2.65e-123 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HLLBMAHE_00320 1.65e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_00321 5.4e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
HLLBMAHE_00322 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HLLBMAHE_00323 2.27e-220 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HLLBMAHE_00324 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLLBMAHE_00325 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLLBMAHE_00326 8.1e-236 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLLBMAHE_00327 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
HLLBMAHE_00328 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HLLBMAHE_00329 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
HLLBMAHE_00330 4.1e-176 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
HLLBMAHE_00331 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
HLLBMAHE_00332 8.49e-245 yceH - - P - - - Belongs to the TelA family
HLLBMAHE_00333 3.26e-72 - - - L - - - transposase activity
HLLBMAHE_00334 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HLLBMAHE_00335 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
HLLBMAHE_00336 1.19e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
HLLBMAHE_00337 1.38e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLLBMAHE_00338 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
HLLBMAHE_00339 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HLLBMAHE_00340 1.16e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
HLLBMAHE_00341 2.4e-277 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
HLLBMAHE_00342 2.63e-210 ycgA - - S - - - Membrane
HLLBMAHE_00343 3.35e-81 ycgA - - S - - - Membrane
HLLBMAHE_00344 2.72e-105 ycgB - - - - - - -
HLLBMAHE_00345 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HLLBMAHE_00346 9.23e-122 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
HLLBMAHE_00347 1.69e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
HLLBMAHE_00348 2.38e-82 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HLLBMAHE_00349 1.33e-268 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HLLBMAHE_00350 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
HLLBMAHE_00351 8.63e-97 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_00352 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
HLLBMAHE_00353 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HLLBMAHE_00354 4.21e-137 tmrB - - S - - - AAA domain
HLLBMAHE_00356 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HLLBMAHE_00357 5.6e-173 - - - L - - - Integrase core domain
HLLBMAHE_00358 7.55e-59 orfX1 - - L - - - Transposase
HLLBMAHE_00359 4.85e-182 - - - Q - - - ubiE/COQ5 methyltransferase family
HLLBMAHE_00360 1.04e-223 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
HLLBMAHE_00361 7.75e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
HLLBMAHE_00362 1.29e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
HLLBMAHE_00363 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HLLBMAHE_00364 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLLBMAHE_00365 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLLBMAHE_00366 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
HLLBMAHE_00367 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
HLLBMAHE_00368 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
HLLBMAHE_00369 7.22e-191 ycgS - - I - - - alpha/beta hydrolase fold
HLLBMAHE_00370 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
HLLBMAHE_00371 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HLLBMAHE_00372 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
HLLBMAHE_00373 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HLLBMAHE_00374 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLLBMAHE_00375 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
HLLBMAHE_00376 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HLLBMAHE_00377 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
HLLBMAHE_00378 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
HLLBMAHE_00379 1.1e-140 yciC - - S - - - GTPases (G3E family)
HLLBMAHE_00380 2.26e-123 yciC - - S - - - GTPases (G3E family)
HLLBMAHE_00381 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HLLBMAHE_00382 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HLLBMAHE_00385 1.11e-96 yckC - - S - - - membrane
HLLBMAHE_00386 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
HLLBMAHE_00387 1.06e-57 - - - K - - - MarR family
HLLBMAHE_00388 2.49e-27 - - - - - - - -
HLLBMAHE_00389 1.16e-154 - - - S - - - AAA domain
HLLBMAHE_00390 7.27e-32 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_00391 1.73e-235 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_00392 4.37e-62 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_00393 3.36e-91 nin - - S - - - Competence protein J (ComJ)
HLLBMAHE_00394 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
HLLBMAHE_00395 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_00396 1.34e-162 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_00397 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
HLLBMAHE_00398 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
HLLBMAHE_00399 5.93e-85 hxlR - - K - - - transcriptional
HLLBMAHE_00400 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_00401 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_00402 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
HLLBMAHE_00403 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
HLLBMAHE_00404 4.92e-285 - - - EGP - - - Major Facilitator Superfamily
HLLBMAHE_00405 6.28e-124 - - - S - - - YcxB-like protein
HLLBMAHE_00406 1.17e-198 ycxC - - EG - - - EamA-like transporter family
HLLBMAHE_00407 0.0 ycxD - - K - - - GntR family transcriptional regulator
HLLBMAHE_00408 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
HLLBMAHE_00409 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
HLLBMAHE_00410 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HLLBMAHE_00411 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HLLBMAHE_00412 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
HLLBMAHE_00413 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
HLLBMAHE_00414 1.55e-113 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HLLBMAHE_00415 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HLLBMAHE_00416 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
HLLBMAHE_00417 6.45e-55 yclD - - - - - - -
HLLBMAHE_00418 1.84e-200 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
HLLBMAHE_00419 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
HLLBMAHE_00420 0.0 yclG - - M - - - Pectate lyase superfamily protein
HLLBMAHE_00422 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HLLBMAHE_00423 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
HLLBMAHE_00424 3.33e-247 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
HLLBMAHE_00425 1.38e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
HLLBMAHE_00426 5.33e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
HLLBMAHE_00427 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_00428 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HLLBMAHE_00429 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HLLBMAHE_00431 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HLLBMAHE_00432 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HLLBMAHE_00434 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_00435 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_00436 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_00437 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
HLLBMAHE_00438 1.61e-26 - - - V - - - Restriction endonuclease
HLLBMAHE_00439 1.07e-52 - - - V - - - Restriction endonuclease
HLLBMAHE_00440 0.0 ycnB - - EGP - - - the major facilitator superfamily
HLLBMAHE_00441 5.87e-198 ycnC - - K - - - Transcriptional regulator
HLLBMAHE_00442 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HLLBMAHE_00443 1.68e-60 ycnE - - S - - - Monooxygenase
HLLBMAHE_00444 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLLBMAHE_00445 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLBMAHE_00446 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLLBMAHE_00447 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLLBMAHE_00448 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
HLLBMAHE_00449 3.27e-184 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_00450 1.34e-132 ycnI - - S - - - protein conserved in bacteria
HLLBMAHE_00451 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
HLLBMAHE_00452 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HLLBMAHE_00453 1.34e-74 - - - - - - - -
HLLBMAHE_00454 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
HLLBMAHE_00455 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_00456 5.99e-87 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HLLBMAHE_00457 4.92e-265 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
HLLBMAHE_00458 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
HLLBMAHE_00460 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLLBMAHE_00461 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
HLLBMAHE_00462 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
HLLBMAHE_00464 3.15e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
HLLBMAHE_00465 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
HLLBMAHE_00466 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
HLLBMAHE_00467 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
HLLBMAHE_00468 2.8e-170 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
HLLBMAHE_00469 3.31e-237 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
HLLBMAHE_00470 1.55e-170 kipR - - K - - - Transcriptional regulator
HLLBMAHE_00471 1.2e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
HLLBMAHE_00473 8.97e-65 yczJ - - S - - - biosynthesis
HLLBMAHE_00474 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
HLLBMAHE_00475 3.5e-219 ycsN - - S - - - Oxidoreductase
HLLBMAHE_00476 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
HLLBMAHE_00477 0.0 ydaB - - IQ - - - acyl-CoA ligase
HLLBMAHE_00478 1e-127 ydaC - - Q - - - Methyltransferase domain
HLLBMAHE_00479 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_00480 6.76e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
HLLBMAHE_00481 4.12e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLLBMAHE_00482 5.24e-101 ydaG - - S - - - general stress protein
HLLBMAHE_00483 2.65e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HLLBMAHE_00484 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
HLLBMAHE_00485 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HLLBMAHE_00486 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLLBMAHE_00487 4.39e-100 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HLLBMAHE_00488 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
HLLBMAHE_00490 1.84e-34 - - - - - - - -
HLLBMAHE_00491 1.13e-64 sdpB - - S - - - Protein conserved in bacteria
HLLBMAHE_00493 6.14e-53 - - - - - - - -
HLLBMAHE_00494 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
HLLBMAHE_00495 1.67e-42 ydaS - - S - - - membrane
HLLBMAHE_00496 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HLLBMAHE_00497 4.3e-190 ydbA - - P - - - EcsC protein family
HLLBMAHE_00498 1.83e-09 gsiB - - S ko:K06884 - ko00000 general stress protein
HLLBMAHE_00499 2.17e-78 ydbB - - G - - - Cupin domain
HLLBMAHE_00500 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
HLLBMAHE_00501 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
HLLBMAHE_00502 4.99e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HLLBMAHE_00503 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HLLBMAHE_00504 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HLLBMAHE_00505 8.93e-290 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLLBMAHE_00506 5.38e-230 ydbI - - S - - - AI-2E family transporter
HLLBMAHE_00507 5.36e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_00508 4.95e-158 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLLBMAHE_00509 9.32e-70 ydbL - - - - - - -
HLLBMAHE_00510 6.12e-279 ydbM - - I - - - acyl-CoA dehydrogenase
HLLBMAHE_00511 1.49e-26 - - - S - - - Fur-regulated basic protein B
HLLBMAHE_00512 2.1e-11 - - - S - - - Fur-regulated basic protein A
HLLBMAHE_00513 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLLBMAHE_00514 4.19e-75 ydbP - - CO - - - Thioredoxin
HLLBMAHE_00515 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
HLLBMAHE_00516 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HLLBMAHE_00517 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HLLBMAHE_00518 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
HLLBMAHE_00519 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
HLLBMAHE_00520 5.12e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
HLLBMAHE_00521 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HLLBMAHE_00522 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
HLLBMAHE_00523 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLLBMAHE_00524 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HLLBMAHE_00525 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
HLLBMAHE_00526 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
HLLBMAHE_00527 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
HLLBMAHE_00528 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HLLBMAHE_00529 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
HLLBMAHE_00530 1.9e-68 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
HLLBMAHE_00531 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HLLBMAHE_00532 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_00533 1.08e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
HLLBMAHE_00534 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
HLLBMAHE_00535 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
HLLBMAHE_00543 4.46e-153 - - - E - - - amino acid
HLLBMAHE_00544 9.13e-135 ywqM - - K - - - Transcriptional regulator
HLLBMAHE_00545 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
HLLBMAHE_00546 9.99e-59 - - - - - - - -
HLLBMAHE_00547 1.65e-48 - - - S ko:K21493 - ko00000,ko01000,ko02048 LXG domain of WXG superfamily
HLLBMAHE_00548 6.98e-279 - - - L - - - Transposase
HLLBMAHE_00549 4.78e-152 - - - L - - - Bacterial dnaA protein
HLLBMAHE_00550 4.95e-97 - - - M - - - nucleic acid phosphodiester bond hydrolysis
HLLBMAHE_00551 1.54e-46 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HLLBMAHE_00552 2.98e-53 - - - - - - - -
HLLBMAHE_00556 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
HLLBMAHE_00557 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
HLLBMAHE_00558 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
HLLBMAHE_00559 5.97e-174 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLLBMAHE_00560 2.44e-210 - - - K - - - AraC-like ligand binding domain
HLLBMAHE_00561 5.34e-219 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HLLBMAHE_00562 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
HLLBMAHE_00563 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLBMAHE_00564 3.74e-24 ydeG - - EGP - - - Major facilitator superfamily
HLLBMAHE_00565 1.16e-234 ydeG - - EGP - - - Major facilitator superfamily
HLLBMAHE_00566 3.21e-70 ydeH - - - - - - -
HLLBMAHE_00567 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_00568 5.75e-135 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
HLLBMAHE_00569 3.64e-142 - - - - - - - -
HLLBMAHE_00570 2.51e-36 - - - S - - - SNARE associated Golgi protein
HLLBMAHE_00571 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
HLLBMAHE_00572 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
HLLBMAHE_00573 4.66e-197 ydeK - - EG - - - -transporter
HLLBMAHE_00574 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLBMAHE_00575 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
HLLBMAHE_00576 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
HLLBMAHE_00577 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
HLLBMAHE_00578 9.32e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HLLBMAHE_00579 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
HLLBMAHE_00580 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLLBMAHE_00582 8.66e-186 - - - J - - - GNAT acetyltransferase
HLLBMAHE_00583 9.99e-197 - - - EG - - - EamA-like transporter family
HLLBMAHE_00584 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLBMAHE_00585 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
HLLBMAHE_00586 4.04e-149 ydfE - - S - - - Flavin reductase like domain
HLLBMAHE_00587 1.5e-158 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLLBMAHE_00588 1.6e-28 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_00589 4.28e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_00590 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
HLLBMAHE_00591 2.2e-222 - - - S - - - Alpha/beta hydrolase family
HLLBMAHE_00592 7.6e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
HLLBMAHE_00593 2.91e-187 - - - K - - - Bacterial transcription activator, effector binding domain
HLLBMAHE_00594 8.64e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLLBMAHE_00595 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
HLLBMAHE_00596 4.51e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HLLBMAHE_00597 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
HLLBMAHE_00598 2.1e-71 ydfQ - - CO - - - Thioredoxin
HLLBMAHE_00599 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
HLLBMAHE_00600 2.17e-38 - - - - - - - -
HLLBMAHE_00602 4.38e-74 ydfR - - S - - - Protein of unknown function (DUF421)
HLLBMAHE_00603 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
HLLBMAHE_00604 1.05e-158 ydfS - - S - - - Protein of unknown function (DUF421)
HLLBMAHE_00605 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLLBMAHE_00606 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
HLLBMAHE_00607 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
HLLBMAHE_00608 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
HLLBMAHE_00609 5.76e-70 - - - S - - - DoxX-like family
HLLBMAHE_00610 8.04e-111 yycN - - K - - - Acetyltransferase
HLLBMAHE_00611 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
HLLBMAHE_00612 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_00613 1.2e-117 - - - S - - - DinB family
HLLBMAHE_00614 3.99e-102 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLLBMAHE_00615 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
HLLBMAHE_00616 3.71e-146 ydgI - - C - - - nitroreductase
HLLBMAHE_00617 1.9e-89 - - - K - - - Winged helix DNA-binding domain
HLLBMAHE_00618 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
HLLBMAHE_00619 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
HLLBMAHE_00620 8.7e-157 ydhC - - K - - - FCD
HLLBMAHE_00621 7.33e-309 ydhD - - M - - - Glycosyl hydrolase
HLLBMAHE_00622 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLLBMAHE_00623 4.28e-163 - - - - - - - -
HLLBMAHE_00624 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HLLBMAHE_00625 9.2e-87 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
HLLBMAHE_00627 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
HLLBMAHE_00628 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
HLLBMAHE_00629 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
HLLBMAHE_00630 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
HLLBMAHE_00631 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_00632 1.44e-68 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_00633 1.55e-127 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLLBMAHE_00634 1.48e-76 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLLBMAHE_00635 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_00636 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
HLLBMAHE_00637 1.12e-210 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
HLLBMAHE_00638 1.46e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HLLBMAHE_00639 4.57e-269 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
HLLBMAHE_00640 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
HLLBMAHE_00643 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_00646 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HLLBMAHE_00647 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
HLLBMAHE_00648 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
HLLBMAHE_00649 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HLLBMAHE_00650 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HLLBMAHE_00652 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_00653 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
HLLBMAHE_00654 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HLLBMAHE_00655 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HLLBMAHE_00656 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HLLBMAHE_00657 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HLLBMAHE_00658 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
HLLBMAHE_00659 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLLBMAHE_00660 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HLLBMAHE_00661 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HLLBMAHE_00662 1.1e-181 - - - L - - - Belongs to the 'phage' integrase family
HLLBMAHE_00663 1.35e-61 xkdA - - E - - - IrrE N-terminal-like domain
HLLBMAHE_00664 2.92e-43 - - - S - - - Protein of unknown function (DUF4064)
HLLBMAHE_00665 4.37e-84 - - - - - - - -
HLLBMAHE_00667 1.01e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
HLLBMAHE_00668 3e-05 - - - K - - - Helix-turn-helix domain
HLLBMAHE_00669 9.71e-48 - - - - - - - -
HLLBMAHE_00670 1.03e-93 - - - K ko:K07741 - ko00000 BRO family, N-terminal domain
HLLBMAHE_00671 4.65e-112 - - - - - - - -
HLLBMAHE_00676 6.5e-141 - - - S - - - YqaJ-like viral recombinase domain
HLLBMAHE_00677 8.2e-115 recT - - L ko:K07455 - ko00000,ko03400 Recombinational DNA repair protein (RecE pathway)
HLLBMAHE_00678 8.71e-44 yqaL - - L - - - DnaD domain protein
HLLBMAHE_00679 1.53e-165 yqaM - - L - - - IstB-like ATP binding protein
HLLBMAHE_00682 6.2e-28 - - - S - - - YopX protein
HLLBMAHE_00683 1.57e-71 - - - S - - - Protein of unknown function (DUF1064)
HLLBMAHE_00685 6.2e-35 yqaO - - S - - - Phage-like element PBSX protein XtrA
HLLBMAHE_00689 7.6e-56 - - - S - - - dUTPase
HLLBMAHE_00691 1.65e-13 - - - S - - - YopX protein
HLLBMAHE_00698 1.77e-103 - - - L - - - Transposase
HLLBMAHE_00701 5.54e-59 - - - L ko:K07474 - ko00000 Terminase small subunit
HLLBMAHE_00702 1.52e-247 - - - S - - - Phage terminase large subunit
HLLBMAHE_00704 7.6e-151 - - - S - - - Phage portal protein, SPP1 Gp6-like
HLLBMAHE_00705 8.8e-116 - - - S - - - Phage Mu protein F like protein
HLLBMAHE_00707 2.5e-54 - - - S - - - Phage minor structural protein GP20
HLLBMAHE_00708 4.89e-61 - - - S - - - viral capsid
HLLBMAHE_00710 3.04e-38 - - - S - - - Phage gp6-like head-tail connector protein
HLLBMAHE_00711 1.86e-36 - - - S - - - Phage head-tail joining protein
HLLBMAHE_00712 1.74e-47 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HLLBMAHE_00713 4.91e-39 - - - S - - - Protein of unknown function (DUF3168)
HLLBMAHE_00714 1.14e-44 - - - S - - - Phage tail tube protein
HLLBMAHE_00715 5.84e-10 chiA - - G - - - Belongs to the glycosyl hydrolase 18 family
HLLBMAHE_00716 2.58e-37 - - - S - - - Phage tail assembly chaperone protein, TAC
HLLBMAHE_00717 4.13e-202 - - - - - - - -
HLLBMAHE_00718 2.37e-12 - - - S - - - phage tail component
HLLBMAHE_00719 8.45e-270 - - - L - - - Phage minor structural protein
HLLBMAHE_00723 1.95e-37 xhlA - - S - - - Haemolysin XhlA
HLLBMAHE_00724 1.58e-41 xhlB - - S - - - SPP1 phage holin
HLLBMAHE_00725 6.56e-137 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HLLBMAHE_00726 7.52e-55 - - - S - - - protein domain associated with
HLLBMAHE_00728 4.75e-38 - - - K - - - Helix-turn-helix domain
HLLBMAHE_00731 2.18e-54 - - - U ko:K03071 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03110 Preprotein translocase subunit SecB
HLLBMAHE_00733 5.94e-119 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
HLLBMAHE_00735 2.28e-72 - - - KOT ko:K07813 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01002 accessory gene regulator B
HLLBMAHE_00736 1.27e-71 - 2.7.13.3 - T ko:K07706 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 protein histidine kinase activity
HLLBMAHE_00738 2.8e-240 lcnDR2 - - V - - - Lanthionine synthetase C-like protein
HLLBMAHE_00741 3.93e-164 - - - V - - - PFAM Lanthionine synthetase
HLLBMAHE_00742 6.02e-266 lanT - - V ko:K06148,ko:K13409,ko:K20344,ko:K20386 ko02010,ko02024,ko04626,map02010,map02024,map04626 ko00000,ko00001,ko00002,ko02000,ko02044 Peptidase C39 family
HLLBMAHE_00743 4.13e-43 - - - - - - - -
HLLBMAHE_00744 1.23e-174 bcrA1 - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_00745 5.74e-124 bcrB1 - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_00746 9.86e-142 mrsE1 - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_00747 7.82e-35 lanR - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
HLLBMAHE_00748 2.62e-144 - - - V ko:K20459 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_00749 4.62e-85 - - - S ko:K20460 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_00750 2.68e-117 - - - S ko:K20461 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_00751 4.21e-220 - - - O ko:K20486 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000,ko01002 COG1404 Subtilisin-like serine proteases
HLLBMAHE_00752 3.53e-202 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HLLBMAHE_00753 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
HLLBMAHE_00754 1.14e-253 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
HLLBMAHE_00755 3.84e-312 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
HLLBMAHE_00756 2.99e-221 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
HLLBMAHE_00757 8.88e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
HLLBMAHE_00758 3.64e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLLBMAHE_00759 3.21e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
HLLBMAHE_00760 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
HLLBMAHE_00761 4.11e-183 - - - S - - - Ion transport 2 domain protein
HLLBMAHE_00762 1.91e-33 - - - S - - - Ion transport 2 domain protein
HLLBMAHE_00763 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_00764 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
HLLBMAHE_00765 1.79e-84 ydjM - - M - - - Lytic transglycolase
HLLBMAHE_00766 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
HLLBMAHE_00767 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HLLBMAHE_00768 3.26e-72 - - - L - - - transposase activity
HLLBMAHE_00770 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
HLLBMAHE_00771 1.46e-201 - - - I - - - Alpha/beta hydrolase family
HLLBMAHE_00772 1.44e-228 yeaA - - S - - - Protein of unknown function (DUF4003)
HLLBMAHE_00773 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
HLLBMAHE_00774 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_00775 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HLLBMAHE_00776 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
HLLBMAHE_00777 3.74e-284 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HLLBMAHE_00778 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
HLLBMAHE_00779 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
HLLBMAHE_00780 6.3e-111 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_00781 1.97e-315 - - - S - - - Domain of unknown function (DUF4179)
HLLBMAHE_00782 4.65e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
HLLBMAHE_00783 9.69e-164 yebC - - M - - - Membrane
HLLBMAHE_00785 2.66e-120 yebE - - S - - - UPF0316 protein
HLLBMAHE_00786 3.13e-38 yebG - - S - - - NETI protein
HLLBMAHE_00787 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HLLBMAHE_00788 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HLLBMAHE_00789 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HLLBMAHE_00790 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
HLLBMAHE_00791 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLLBMAHE_00792 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLLBMAHE_00793 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HLLBMAHE_00794 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HLLBMAHE_00795 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
HLLBMAHE_00796 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HLLBMAHE_00797 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
HLLBMAHE_00798 2.32e-297 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
HLLBMAHE_00799 5.06e-94 - - - K - - - helix_turn_helix ASNC type
HLLBMAHE_00800 1.87e-288 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
HLLBMAHE_00801 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
HLLBMAHE_00802 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
HLLBMAHE_00803 1.25e-239 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
HLLBMAHE_00804 6.27e-67 yerC - - S - - - protein conserved in bacteria
HLLBMAHE_00805 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
HLLBMAHE_00807 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HLLBMAHE_00808 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
HLLBMAHE_00809 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HLLBMAHE_00810 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
HLLBMAHE_00811 3.26e-72 - - - L - - - transposase activity
HLLBMAHE_00812 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HLLBMAHE_00813 3.49e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
HLLBMAHE_00814 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
HLLBMAHE_00815 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLLBMAHE_00816 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLLBMAHE_00817 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HLLBMAHE_00818 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HLLBMAHE_00820 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_00821 6.97e-189 yerO - - K - - - Transcriptional regulator
HLLBMAHE_00822 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HLLBMAHE_00823 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLLBMAHE_00824 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLLBMAHE_00826 4.21e-302 - - - L - - - PFAM transposase IS66
HLLBMAHE_00827 7.21e-74 - - - L ko:K07484 - ko00000 Family membership
HLLBMAHE_00828 2.53e-44 - - - S - - - Family membership
HLLBMAHE_00829 7.19e-10 - - - L - - - PFAM Integrase catalytic
HLLBMAHE_00830 2.17e-268 - - - L - - - PFAM transposase IS116 IS110 IS902 family
HLLBMAHE_00831 8.67e-251 - - - L - - - COG4584 Transposase and inactivated derivatives
HLLBMAHE_00832 2.41e-159 - - - L - - - Bacterial dnaA protein
HLLBMAHE_00833 3.07e-94 - - GT2 M ko:K11936 ko02026,map02026 ko00000,ko00001,ko01000,ko01003,ko02000 glycosyl transferase family 2
HLLBMAHE_00834 1.41e-59 - - - G - - - Cupin 2, conserved barrel domain protein
HLLBMAHE_00835 0.0 - - - E - - - Zn peptidase
HLLBMAHE_00836 2.44e-123 - - - K - - - DNA-templated transcription, initiation
HLLBMAHE_00837 6.66e-43 - - - - - - - -
HLLBMAHE_00838 1.64e-59 - - - - - - - -
HLLBMAHE_00839 3.02e-275 - - - L - - - Protein of unknown function (DUF2800)
HLLBMAHE_00840 5.42e-128 - - - S - - - Protein of unknown function (DUF2815)
HLLBMAHE_00841 0.0 - 2.7.7.7 - L ko:K02334 - ko00000,ko01000 DNA polymerase A domain
HLLBMAHE_00842 0.0 - - - K - - - SIR2-like domain
HLLBMAHE_00844 1.41e-72 - - - S - - - Protein of unknown function, DUF600
HLLBMAHE_00845 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HLLBMAHE_00847 5.68e-126 - - - L - - - endonuclease activity
HLLBMAHE_00848 1.23e-14 - - - S - - - Pfam:DUF1311
HLLBMAHE_00849 1.73e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
HLLBMAHE_00851 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
HLLBMAHE_00853 2.85e-129 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_00854 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
HLLBMAHE_00855 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
HLLBMAHE_00856 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
HLLBMAHE_00857 9.78e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
HLLBMAHE_00859 4.8e-133 yesL - - S - - - Protein of unknown function, DUF624
HLLBMAHE_00860 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_00861 8.25e-162 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HLLBMAHE_00862 1.39e-51 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
HLLBMAHE_00863 2.91e-314 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
HLLBMAHE_00864 5.79e-218 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLLBMAHE_00865 1.25e-21 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLLBMAHE_00866 3.4e-116 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HLLBMAHE_00867 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
HLLBMAHE_00868 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
HLLBMAHE_00869 2.73e-80 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HLLBMAHE_00870 1.47e-153 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HLLBMAHE_00871 3.42e-192 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
HLLBMAHE_00872 2.25e-127 yetA - - - - - - -
HLLBMAHE_00873 5.02e-234 yetA - - - - - - -
HLLBMAHE_00874 1.54e-213 yetA - - - - - - -
HLLBMAHE_00875 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HLLBMAHE_00876 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HLLBMAHE_00877 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLLBMAHE_00878 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HLLBMAHE_00879 3.66e-157 yetF - - S - - - membrane
HLLBMAHE_00880 3.26e-72 - - - L - - - transposase activity
HLLBMAHE_00881 1.04e-139 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HLLBMAHE_00882 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_00883 4.67e-73 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
HLLBMAHE_00884 1.16e-35 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_00885 9.04e-17 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_00886 1.44e-180 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLLBMAHE_00887 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
HLLBMAHE_00888 5.15e-135 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
HLLBMAHE_00889 1.24e-194 - - - EG - - - EamA-like transporter family
HLLBMAHE_00891 7.55e-59 orfX1 - - L - - - Transposase
HLLBMAHE_00892 5.6e-173 - - - L - - - Integrase core domain
HLLBMAHE_00893 2.04e-253 yetN - - S - - - Protein of unknown function (DUF3900)
HLLBMAHE_00894 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HLLBMAHE_00895 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HLLBMAHE_00896 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
HLLBMAHE_00897 1.03e-238 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
HLLBMAHE_00898 1.1e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
HLLBMAHE_00899 6.42e-282 yfnE - - S - - - Glycosyltransferase like family 2
HLLBMAHE_00900 2.73e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
HLLBMAHE_00901 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_00902 1.61e-162 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HLLBMAHE_00903 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
HLLBMAHE_00904 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLLBMAHE_00905 5.14e-161 yfmS - - NT - - - chemotaxis protein
HLLBMAHE_00906 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLLBMAHE_00907 3.09e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
HLLBMAHE_00908 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
HLLBMAHE_00909 1.46e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
HLLBMAHE_00910 5.3e-47 - - - - - - - -
HLLBMAHE_00911 3.26e-72 - - - L - - - transposase activity
HLLBMAHE_00912 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HLLBMAHE_00913 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLLBMAHE_00914 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
HLLBMAHE_00915 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
HLLBMAHE_00916 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_00917 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
HLLBMAHE_00918 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
HLLBMAHE_00919 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_00920 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_00921 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HLLBMAHE_00922 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
HLLBMAHE_00923 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
HLLBMAHE_00924 3.34e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
HLLBMAHE_00925 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
HLLBMAHE_00926 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HLLBMAHE_00927 1.33e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
HLLBMAHE_00928 3.98e-230 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
HLLBMAHE_00929 8.47e-285 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HLLBMAHE_00930 3.43e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HLLBMAHE_00931 6.53e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HLLBMAHE_00932 2.54e-60 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
HLLBMAHE_00933 3.42e-157 yflK - - S - - - protein conserved in bacteria
HLLBMAHE_00934 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
HLLBMAHE_00935 6.9e-27 yflI - - - - - - -
HLLBMAHE_00936 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
HLLBMAHE_00937 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
HLLBMAHE_00938 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HLLBMAHE_00939 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HLLBMAHE_00940 5.41e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
HLLBMAHE_00941 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
HLLBMAHE_00942 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
HLLBMAHE_00943 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_00944 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
HLLBMAHE_00945 5.05e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
HLLBMAHE_00946 6.16e-160 frp - - C - - - nitroreductase
HLLBMAHE_00947 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HLLBMAHE_00948 5.48e-114 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HLLBMAHE_00949 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_00950 6.93e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_00951 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
HLLBMAHE_00952 2.5e-109 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLLBMAHE_00953 1.03e-66 yfkI - - S - - - gas vesicle protein
HLLBMAHE_00954 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
HLLBMAHE_00955 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_00956 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
HLLBMAHE_00957 3.69e-189 yfkD - - S - - - YfkD-like protein
HLLBMAHE_00958 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
HLLBMAHE_00959 1.76e-283 yfkA - - S - - - YfkB-like domain
HLLBMAHE_00960 3.26e-36 yfjT - - - - - - -
HLLBMAHE_00961 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
HLLBMAHE_00962 8.44e-159 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HLLBMAHE_00963 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
HLLBMAHE_00964 2.65e-212 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HLLBMAHE_00965 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HLLBMAHE_00966 4.32e-59 - - - S - - - YfzA-like protein
HLLBMAHE_00967 7.83e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HLLBMAHE_00968 4.55e-109 yfjM - - S - - - Psort location Cytoplasmic, score
HLLBMAHE_00970 3.91e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLLBMAHE_00971 4.56e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLLBMAHE_00972 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLLBMAHE_00973 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLLBMAHE_00974 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
HLLBMAHE_00975 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
HLLBMAHE_00976 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
HLLBMAHE_00977 1e-105 - - - S - - - Family of unknown function (DUF5381)
HLLBMAHE_00978 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
HLLBMAHE_00979 1.02e-184 yfjC - - - - - - -
HLLBMAHE_00980 1.94e-270 yfjB - - - - - - -
HLLBMAHE_00981 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
HLLBMAHE_00982 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLLBMAHE_00983 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
HLLBMAHE_00984 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_00985 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
HLLBMAHE_00986 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
HLLBMAHE_00987 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HLLBMAHE_00988 2.01e-84 yfiD3 - - S - - - DoxX
HLLBMAHE_00989 7.28e-209 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
HLLBMAHE_00990 1.28e-228 - - - K ko:K02099 - ko00000,ko03000 AraC-like ligand binding domain
HLLBMAHE_00991 0.0 yfiG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_00992 5.47e-234 - - - G - - - Xylose isomerase
HLLBMAHE_00993 2.46e-32 - - - S - - - Oxidoreductase
HLLBMAHE_00994 4.36e-249 - - - S - - - Oxidoreductase
HLLBMAHE_00996 1.7e-272 baeS - - T - - - Histidine kinase
HLLBMAHE_00997 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
HLLBMAHE_00998 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_00999 1.25e-265 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_01000 6.93e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HLLBMAHE_01001 1.89e-128 padR - - K - - - transcriptional
HLLBMAHE_01002 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
HLLBMAHE_01003 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HLLBMAHE_01004 4e-128 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
HLLBMAHE_01005 0.0 yfiU - - EGP - - - the major facilitator superfamily
HLLBMAHE_01006 2.11e-103 yfiV - - K - - - transcriptional
HLLBMAHE_01007 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HLLBMAHE_01008 4.47e-230 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HLLBMAHE_01009 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_01010 2.11e-228 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_01011 3.1e-214 yfhB - - S - - - PhzF family
HLLBMAHE_01012 2.87e-138 yfhC - - C - - - nitroreductase
HLLBMAHE_01013 8.86e-35 yfhD - - S - - - YfhD-like protein
HLLBMAHE_01015 1.54e-219 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
HLLBMAHE_01016 1.88e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
HLLBMAHE_01017 2.66e-68 yfhH - - S - - - Protein of unknown function (DUF1811)
HLLBMAHE_01019 2.45e-268 yfhI - - EGP - - - -transporter
HLLBMAHE_01020 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
HLLBMAHE_01021 8.95e-60 yfhJ - - S - - - WVELL protein
HLLBMAHE_01022 1.91e-114 yfhK - - T - - - Bacterial SH3 domain homologues
HLLBMAHE_01023 8.95e-66 yfhL - - S - - - SdpI/YhfL protein family
HLLBMAHE_01024 4.59e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
HLLBMAHE_01025 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLBMAHE_01026 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
HLLBMAHE_01027 1.7e-235 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
HLLBMAHE_01028 1.31e-265 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
HLLBMAHE_01029 1.73e-48 yfhS - - - - - - -
HLLBMAHE_01030 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_01031 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
HLLBMAHE_01032 7.66e-63 ygaB - - S - - - YgaB-like protein
HLLBMAHE_01033 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
HLLBMAHE_01034 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
HLLBMAHE_01035 1.87e-238 ygaE - - S - - - Membrane
HLLBMAHE_01036 1.33e-311 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HLLBMAHE_01037 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
HLLBMAHE_01038 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
HLLBMAHE_01039 3.38e-73 ygzB - - S - - - UPF0295 protein
HLLBMAHE_01040 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
HLLBMAHE_01041 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_01058 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
HLLBMAHE_01059 1.58e-36 - - - - - - - -
HLLBMAHE_01060 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
HLLBMAHE_01061 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HLLBMAHE_01063 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HLLBMAHE_01064 1.23e-176 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HLLBMAHE_01065 5.1e-219 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
HLLBMAHE_01066 8.33e-190 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLLBMAHE_01067 7.68e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
HLLBMAHE_01069 5.64e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HLLBMAHE_01070 5.19e-98 ygaO - - - - - - -
HLLBMAHE_01071 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01073 1.84e-145 yhzB - - S - - - B3/4 domain
HLLBMAHE_01074 2.07e-284 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HLLBMAHE_01075 2.77e-225 yhbB - - S - - - Putative amidase domain
HLLBMAHE_01076 6.53e-113 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HLLBMAHE_01077 1.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
HLLBMAHE_01078 2.17e-94 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HLLBMAHE_01079 2.34e-102 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
HLLBMAHE_01080 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
HLLBMAHE_01081 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
HLLBMAHE_01082 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
HLLBMAHE_01083 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
HLLBMAHE_01084 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
HLLBMAHE_01085 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
HLLBMAHE_01086 3.95e-59 yhcC - - - - - - -
HLLBMAHE_01087 2.06e-69 - - - - - - - -
HLLBMAHE_01088 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01089 3.24e-156 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_01090 1.25e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_01091 8.11e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLLBMAHE_01092 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HLLBMAHE_01093 5.24e-193 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
HLLBMAHE_01094 3.36e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
HLLBMAHE_01095 7.5e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLLBMAHE_01096 2.24e-91 ydcL - - L - - - Belongs to the 'phage' integrase family
HLLBMAHE_01097 1.15e-50 - - - E - - - Pfam:DUF955
HLLBMAHE_01098 2.14e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
HLLBMAHE_01099 2.06e-10 - - - - - - - -
HLLBMAHE_01100 3.34e-47 - - - - - - - -
HLLBMAHE_01102 4.51e-84 - - - S - - - Bacterial protein of unknown function (DUF961)
HLLBMAHE_01103 0.0 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
HLLBMAHE_01104 4.49e-155 ydcQ - - D ko:K03466 - ko00000,ko03036 Ftsk spoiiie family protein
HLLBMAHE_01105 4.47e-255 nicK - - L ko:K07467 - ko00000 Replication initiation factor
HLLBMAHE_01108 1.38e-43 yddA - - - - - - -
HLLBMAHE_01109 2.78e-218 yddB - - S - - - Conjugative transposon protein TcpC
HLLBMAHE_01110 1.63e-52 yddC - - - - - - -
HLLBMAHE_01111 2.82e-117 yddD - - S - - - TcpE family
HLLBMAHE_01112 0.0 yddE - - S - - - AAA-like domain
HLLBMAHE_01113 5.47e-63 - - - S - - - Domain of unknown function (DUF1874)
HLLBMAHE_01114 0.0 yddG - - S - - - maturation of SSU-rRNA
HLLBMAHE_01115 1.85e-240 yddH - - M - - - Lysozyme-like
HLLBMAHE_01116 6.45e-111 yddI - - - - - - -
HLLBMAHE_01117 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
HLLBMAHE_01118 7.39e-72 - - - S - - - Domain of unknown function (DUF4145)
HLLBMAHE_01119 6.13e-84 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_01121 1.19e-114 - - - S - - - Protein of unknown function (DUF2812)
HLLBMAHE_01122 1.31e-64 - - - K - - - Transcriptional regulator PadR-like family
HLLBMAHE_01123 1.96e-71 yhcM - - - - - - -
HLLBMAHE_01124 6.46e-103 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLLBMAHE_01126 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_01127 1.19e-195 yhcP - - - - - - -
HLLBMAHE_01128 1.68e-146 yhcQ - - M - - - Spore coat protein
HLLBMAHE_01129 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HLLBMAHE_01130 1.52e-135 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HLLBMAHE_01131 2.76e-217 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HLLBMAHE_01132 2.47e-88 yhcU - - S - - - Family of unknown function (DUF5365)
HLLBMAHE_01133 1.76e-90 yhcV - - S - - - COG0517 FOG CBS domain
HLLBMAHE_01134 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
HLLBMAHE_01135 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLLBMAHE_01136 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLLBMAHE_01137 8.88e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HLLBMAHE_01138 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
HLLBMAHE_01139 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HLLBMAHE_01140 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HLLBMAHE_01141 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
HLLBMAHE_01142 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_01143 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_01144 1.9e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
HLLBMAHE_01145 1.65e-51 yhdB - - S - - - YhdB-like protein
HLLBMAHE_01146 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
HLLBMAHE_01147 1.14e-273 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HLLBMAHE_01148 1.6e-98 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
HLLBMAHE_01149 1.44e-304 ygxB - - M - - - Conserved TM helix
HLLBMAHE_01150 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
HLLBMAHE_01151 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
HLLBMAHE_01152 1.19e-202 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HLLBMAHE_01153 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01154 1.84e-198 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HLLBMAHE_01155 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLBMAHE_01156 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLBMAHE_01157 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
HLLBMAHE_01158 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
HLLBMAHE_01159 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_01160 6.74e-244 yhdN - - C - - - Aldo keto reductase
HLLBMAHE_01161 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLLBMAHE_01162 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HLLBMAHE_01163 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
HLLBMAHE_01164 2.95e-283 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HLLBMAHE_01165 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
HLLBMAHE_01166 2.04e-65 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLLBMAHE_01167 1.67e-86 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HLLBMAHE_01168 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HLLBMAHE_01169 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
HLLBMAHE_01170 1.13e-237 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
HLLBMAHE_01171 1.98e-178 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HLLBMAHE_01172 4.13e-193 nodB1 - - G - - - deacetylase
HLLBMAHE_01173 9.07e-197 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HLLBMAHE_01174 1.4e-300 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HLLBMAHE_01175 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
HLLBMAHE_01176 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HLLBMAHE_01177 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HLLBMAHE_01178 7.48e-140 yheG - - GM - - - NAD(P)H-binding
HLLBMAHE_01179 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HLLBMAHE_01180 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
HLLBMAHE_01181 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
HLLBMAHE_01182 3.37e-276 yheC - - HJ - - - YheC/D like ATP-grasp
HLLBMAHE_01183 7.19e-260 yheB - - S - - - Belongs to the UPF0754 family
HLLBMAHE_01184 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
HLLBMAHE_01185 1.06e-260 yhaZ - - L - - - DNA alkylation repair enzyme
HLLBMAHE_01186 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
HLLBMAHE_01187 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
HLLBMAHE_01188 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
HLLBMAHE_01189 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HLLBMAHE_01191 2.28e-172 yhaR - - I - - - enoyl-CoA hydratase
HLLBMAHE_01192 9.36e-36 - - - S - - - YhzD-like protein
HLLBMAHE_01193 3.76e-213 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_01194 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
HLLBMAHE_01195 1.57e-299 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
HLLBMAHE_01196 0.0 yhaN - - L - - - AAA domain
HLLBMAHE_01197 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
HLLBMAHE_01198 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
HLLBMAHE_01199 2.33e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HLLBMAHE_01200 1.4e-116 yhaK - - S - - - Putative zincin peptidase
HLLBMAHE_01201 3.46e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
HLLBMAHE_01202 8.17e-147 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
HLLBMAHE_01203 3.89e-54 yhaH - - S - - - YtxH-like protein
HLLBMAHE_01204 9.66e-30 - - - - - - - -
HLLBMAHE_01205 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
HLLBMAHE_01206 2.15e-261 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HLLBMAHE_01207 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HLLBMAHE_01208 6.35e-175 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
HLLBMAHE_01209 3.11e-272 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HLLBMAHE_01210 2.89e-161 ecsC - - S - - - EcsC protein family
HLLBMAHE_01211 3.63e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HLLBMAHE_01212 1.28e-310 yhfA - - C - - - membrane
HLLBMAHE_01213 1e-44 - - - C - - - Rubrerythrin
HLLBMAHE_01214 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
HLLBMAHE_01215 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HLLBMAHE_01216 2.14e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HLLBMAHE_01217 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
HLLBMAHE_01218 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HLLBMAHE_01219 5.79e-132 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01220 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
HLLBMAHE_01221 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLLBMAHE_01222 1.27e-175 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
HLLBMAHE_01224 1.55e-252 yhfE - - G - - - peptidase M42
HLLBMAHE_01225 7.28e-92 - - - S - - - ASCH
HLLBMAHE_01226 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HLLBMAHE_01227 5.93e-183 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HLLBMAHE_01228 1.66e-244 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
HLLBMAHE_01229 1.23e-142 yhfK - - GM - - - NmrA-like family
HLLBMAHE_01230 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HLLBMAHE_01231 2.28e-84 yhfM - - - - - - -
HLLBMAHE_01232 4.58e-306 yhfN - - O - - - Peptidase M48
HLLBMAHE_01233 6.91e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HLLBMAHE_01234 6.23e-102 - - - K - - - acetyltransferase
HLLBMAHE_01235 9.78e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
HLLBMAHE_01236 9.26e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
HLLBMAHE_01237 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
HLLBMAHE_01238 4.25e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HLLBMAHE_01239 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
HLLBMAHE_01240 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
HLLBMAHE_01241 1.85e-260 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
HLLBMAHE_01242 0.0 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
HLLBMAHE_01243 2.24e-203 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_01244 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_01245 9.84e-45 yhzC - - S - - - IDEAL
HLLBMAHE_01246 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
HLLBMAHE_01247 1.04e-215 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HLLBMAHE_01248 2.04e-56 yhjA - - S - - - Excalibur calcium-binding domain
HLLBMAHE_01249 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLLBMAHE_01250 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
HLLBMAHE_01251 4.13e-78 yhjD - - - - - - -
HLLBMAHE_01252 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
HLLBMAHE_01253 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLLBMAHE_01254 4.21e-88 yhjG - - CH - - - FAD binding domain
HLLBMAHE_01255 3.58e-207 yhjG - - CH - - - FAD binding domain
HLLBMAHE_01256 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLLBMAHE_01259 6.05e-270 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
HLLBMAHE_01260 3.98e-257 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HLLBMAHE_01261 4.19e-202 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
HLLBMAHE_01262 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HLLBMAHE_01263 1.46e-237 yhjM - - K - - - Transcriptional regulator
HLLBMAHE_01264 1.02e-258 yhjN - - S ko:K07120 - ko00000 membrane
HLLBMAHE_01265 2.15e-264 - - - EGP - - - Transmembrane secretion effector
HLLBMAHE_01266 3.34e-153 - - - S - - - Sugar transport-related sRNA regulator N-term
HLLBMAHE_01267 2.33e-233 - - - S - - - Sugar transport-related sRNA regulator N-term
HLLBMAHE_01268 7.65e-101 yhjR - - S - - - Rubrerythrin
HLLBMAHE_01269 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
HLLBMAHE_01270 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
HLLBMAHE_01271 4.67e-279 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HLLBMAHE_01272 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
HLLBMAHE_01273 2.15e-63 yisB - - V - - - COG1403 Restriction endonuclease
HLLBMAHE_01274 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
HLLBMAHE_01275 1.53e-83 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
HLLBMAHE_01276 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
HLLBMAHE_01277 3.34e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
HLLBMAHE_01278 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
HLLBMAHE_01279 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
HLLBMAHE_01280 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
HLLBMAHE_01281 7.35e-220 cotH - - M ko:K06330 - ko00000 Spore Coat
HLLBMAHE_01282 2.66e-219 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HLLBMAHE_01283 2.05e-74 yisL - - S - - - UPF0344 protein
HLLBMAHE_01284 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HLLBMAHE_01285 3.68e-132 yisN - - S - - - Protein of unknown function (DUF2777)
HLLBMAHE_01286 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HLLBMAHE_01287 1.85e-115 yizA - - S - - - Damage-inducible protein DinB
HLLBMAHE_01288 1.32e-190 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
HLLBMAHE_01289 1.01e-310 yisQ - - V - - - Mate efflux family protein
HLLBMAHE_01290 1.41e-207 yisR - - K - - - Transcriptional regulator
HLLBMAHE_01291 8.71e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
HLLBMAHE_01292 4.07e-246 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
HLLBMAHE_01293 3.89e-117 yisT - - S - - - DinB family
HLLBMAHE_01294 1.05e-137 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
HLLBMAHE_01295 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HLLBMAHE_01296 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
HLLBMAHE_01297 1.07e-197 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLLBMAHE_01298 4.06e-145 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HLLBMAHE_01299 1.87e-293 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HLLBMAHE_01300 6.43e-183 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HLLBMAHE_01301 1.34e-162 - 3.1.3.71 - H ko:K05979 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the ComB family
HLLBMAHE_01302 4.31e-180 yitD 4.4.1.19 - S ko:K08097 ko00680,ko01120,map00680,map01120 ko00000,ko00001,ko00002,ko01000 synthase
HLLBMAHE_01303 6.62e-140 yitE - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLLBMAHE_01304 5.04e-282 yitF 5.5.1.27 - M ko:K18983 ko00053,map00053 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HLLBMAHE_01305 6.91e-12 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_01306 2.4e-263 yitG - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_01307 4.19e-202 yitH - - K - - - Acetyltransferase (GNAT) domain
HLLBMAHE_01308 7.28e-101 - - - S - - - Acetyltransferase (GNAT) domain
HLLBMAHE_01309 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HLLBMAHE_01310 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
HLLBMAHE_01311 3.08e-201 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
HLLBMAHE_01312 4.16e-122 - - - - - - - -
HLLBMAHE_01313 1.42e-218 - - - - - - - -
HLLBMAHE_01314 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
HLLBMAHE_01315 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
HLLBMAHE_01316 2.9e-118 - - - - - - - -
HLLBMAHE_01317 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
HLLBMAHE_01318 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HLLBMAHE_01319 3.05e-200 yitS - - S - - - protein conserved in bacteria
HLLBMAHE_01320 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HLLBMAHE_01321 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
HLLBMAHE_01322 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
HLLBMAHE_01323 1.92e-08 - - - - - - - -
HLLBMAHE_01324 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HLLBMAHE_01325 1.45e-184 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HLLBMAHE_01326 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
HLLBMAHE_01327 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
HLLBMAHE_01328 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
HLLBMAHE_01329 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
HLLBMAHE_01330 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
HLLBMAHE_01331 1.01e-252 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HLLBMAHE_01332 1.01e-292 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HLLBMAHE_01333 1.27e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
HLLBMAHE_01334 6.59e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
HLLBMAHE_01335 5.48e-261 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HLLBMAHE_01336 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
HLLBMAHE_01337 6.07e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HLLBMAHE_01338 2.51e-39 yjzC - - S - - - YjzC-like protein
HLLBMAHE_01339 8.84e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
HLLBMAHE_01340 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
HLLBMAHE_01341 8.63e-131 yjaV - - - - - - -
HLLBMAHE_01342 7.48e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
HLLBMAHE_01343 1.07e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
HLLBMAHE_01344 4.43e-30 yjzB - - - - - - -
HLLBMAHE_01345 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HLLBMAHE_01346 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HLLBMAHE_01347 2.23e-191 yjaZ - - O - - - Zn-dependent protease
HLLBMAHE_01348 1.02e-232 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_01349 1.15e-234 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_01350 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
HLLBMAHE_01351 6.73e-216 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLLBMAHE_01352 1.03e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLLBMAHE_01353 1.84e-189 yjbA - - S - - - Belongs to the UPF0736 family
HLLBMAHE_01354 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
HLLBMAHE_01355 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HLLBMAHE_01356 2.22e-207 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLLBMAHE_01357 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLLBMAHE_01358 2.64e-247 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_01359 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_01360 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
HLLBMAHE_01361 2.65e-133 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLBMAHE_01362 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HLLBMAHE_01363 2.03e-143 yjbE - - P - - - Integral membrane protein TerC family
HLLBMAHE_01364 6.34e-147 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLLBMAHE_01365 1.03e-280 coiA - - S ko:K06198 - ko00000 Competence protein
HLLBMAHE_01366 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
HLLBMAHE_01367 2.68e-28 - - - - - - - -
HLLBMAHE_01368 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HLLBMAHE_01369 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
HLLBMAHE_01370 3.42e-127 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLLBMAHE_01371 2.1e-129 yjbK - - S - - - protein conserved in bacteria
HLLBMAHE_01372 5.35e-81 yjbL - - S - - - Belongs to the UPF0738 family
HLLBMAHE_01373 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
HLLBMAHE_01374 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLLBMAHE_01375 1.49e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
HLLBMAHE_01376 3.3e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HLLBMAHE_01377 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HLLBMAHE_01378 5.7e-177 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HLLBMAHE_01379 2.32e-138 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
HLLBMAHE_01380 1.09e-275 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
HLLBMAHE_01381 2.18e-41 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
HLLBMAHE_01382 6.78e-174 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HLLBMAHE_01383 6.18e-238 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLLBMAHE_01384 8.38e-192 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HLLBMAHE_01385 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
HLLBMAHE_01386 3.63e-104 yjbX - - S - - - Spore coat protein
HLLBMAHE_01387 4.57e-108 cotZ - - S ko:K06344 - ko00000 Spore coat protein
HLLBMAHE_01388 3.12e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
HLLBMAHE_01389 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
HLLBMAHE_01390 1.51e-18 cotW - - - ko:K06341 - ko00000 -
HLLBMAHE_01392 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
HLLBMAHE_01395 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
HLLBMAHE_01396 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HLLBMAHE_01397 6.31e-51 - - - - - - - -
HLLBMAHE_01398 7.75e-94 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLBMAHE_01399 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
HLLBMAHE_01400 3.17e-176 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
HLLBMAHE_01401 1.62e-272 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HLLBMAHE_01402 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HLLBMAHE_01403 7.14e-128 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
HLLBMAHE_01404 2.88e-271 yjcL - - S - - - Protein of unknown function (DUF819)
HLLBMAHE_01406 3.89e-77 - - - S - - - peptidoglycan catabolic process
HLLBMAHE_01408 4.39e-42 - - - S - - - Protein of unknown function (DUF4238)
HLLBMAHE_01409 5.74e-12 lytB 3.2.1.96 - S ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 dextransucrase activity
HLLBMAHE_01410 1.54e-32 - - - S - - - Domain of unknown function (DUF4917)
HLLBMAHE_01411 8.67e-43 - - - S - - - Protein of unknown function (DUF1433)
HLLBMAHE_01412 1.6e-309 - - - I - - - Pfam Lipase (class 3)
HLLBMAHE_01413 1.56e-56 - - - - - - - -
HLLBMAHE_01415 4.35e-125 - - - V - - - HNH nucleases
HLLBMAHE_01416 2.35e-153 - - - S - - - Abortive infection C-terminus
HLLBMAHE_01418 1.23e-101 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_01419 6.76e-108 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_01420 5.19e-61 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
HLLBMAHE_01421 7.72e-178 - 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl-(Acyl carrier protein) reductase
HLLBMAHE_01422 0.000759 - - - - - - - -
HLLBMAHE_01423 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
HLLBMAHE_01424 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_01425 8.45e-239 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HLLBMAHE_01426 1.86e-75 yjdF3 - - S - - - Protein of unknown function (DUF2992)
HLLBMAHE_01427 3.61e-117 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
HLLBMAHE_01429 3.79e-101 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HLLBMAHE_01430 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
HLLBMAHE_01431 9.41e-69 yjdJ - - S - - - Domain of unknown function (DUF4306)
HLLBMAHE_01432 5.31e-224 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLLBMAHE_01434 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
HLLBMAHE_01435 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
HLLBMAHE_01436 1.95e-30 yjfB - - S - - - Putative motility protein
HLLBMAHE_01437 3.24e-219 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
HLLBMAHE_01438 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
HLLBMAHE_01439 1.22e-133 yjgB - - S - - - Domain of unknown function (DUF4309)
HLLBMAHE_01440 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HLLBMAHE_01441 1.6e-122 yjgD - - S - - - Protein of unknown function (DUF1641)
HLLBMAHE_01443 1.91e-149 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
HLLBMAHE_01445 3.48e-288 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HLLBMAHE_01446 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HLLBMAHE_01447 3.2e-41 - - - - - - - -
HLLBMAHE_01448 3.39e-186 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HLLBMAHE_01449 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
HLLBMAHE_01450 1.14e-174 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
HLLBMAHE_01451 1.81e-224 yjlA - - EG - - - Putative multidrug resistance efflux transporter
HLLBMAHE_01452 1e-117 yjlB - - S - - - Cupin domain
HLLBMAHE_01453 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
HLLBMAHE_01454 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HLLBMAHE_01455 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
HLLBMAHE_01456 5.05e-313 - - - G ko:K03292 - ko00000 symporter YjmB
HLLBMAHE_01457 3.6e-242 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
HLLBMAHE_01458 4.58e-246 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
HLLBMAHE_01459 1.12e-169 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HLLBMAHE_01460 1.16e-76 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
HLLBMAHE_01461 2.23e-195 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_01462 1.53e-286 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
HLLBMAHE_01463 5.71e-237 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
HLLBMAHE_01464 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
HLLBMAHE_01465 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
HLLBMAHE_01466 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
HLLBMAHE_01467 2.71e-103 yjoA - - S - - - DinB family
HLLBMAHE_01468 1.75e-313 VCP - - O - - - AAA domain (dynein-related subfamily)
HLLBMAHE_01469 4.97e-271 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_01471 1.79e-55 - - - S - - - YCII-related domain
HLLBMAHE_01472 6.23e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HLLBMAHE_01473 1.35e-80 yjqA - - S - - - Bacterial PH domain
HLLBMAHE_01474 3.89e-139 yjqB - - S - - - Pfam:DUF867
HLLBMAHE_01475 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
HLLBMAHE_01476 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
HLLBMAHE_01477 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
HLLBMAHE_01479 4.36e-202 xkdB - - K - - - sequence-specific DNA binding
HLLBMAHE_01480 3.55e-151 xkdC - - L - - - Bacterial dnaA protein
HLLBMAHE_01484 3.31e-109 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HLLBMAHE_01485 2.27e-177 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
HLLBMAHE_01486 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
HLLBMAHE_01487 0.0 yqbA - - S - - - portal protein
HLLBMAHE_01488 9.88e-177 xkdF3 - - L - - - Putative phage serine protease XkdF
HLLBMAHE_01489 3.91e-217 xkdG - - S - - - Phage capsid family
HLLBMAHE_01490 1.63e-82 yqbG - - S - - - Protein of unknown function (DUF3199)
HLLBMAHE_01491 1.75e-84 yqbH - - S - - - Domain of unknown function (DUF3599)
HLLBMAHE_01492 2.38e-114 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
HLLBMAHE_01493 8.25e-101 xkdJ - - - - - - -
HLLBMAHE_01494 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
HLLBMAHE_01495 6.01e-99 xkdM - - S - - - Phage tail tube protein
HLLBMAHE_01496 3.34e-101 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
HLLBMAHE_01497 0.0 xkdO - - L - - - Transglycosylase SLT domain
HLLBMAHE_01498 9.32e-156 xkdP - - S - - - Lysin motif
HLLBMAHE_01499 2.31e-232 xkdQ - - G - - - NLP P60 protein
HLLBMAHE_01500 1.45e-51 xkdR - - S - - - Protein of unknown function (DUF2577)
HLLBMAHE_01501 1.89e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
HLLBMAHE_01502 2.08e-242 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HLLBMAHE_01503 3.23e-134 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
HLLBMAHE_01504 4.43e-56 - - - - - - - -
HLLBMAHE_01505 5.3e-131 - - - - - - - -
HLLBMAHE_01507 2.42e-15 xkdX - - - - - - -
HLLBMAHE_01508 9.39e-38 xhlA - - S - - - Haemolysin XhlA
HLLBMAHE_01509 8.12e-53 xhlB - - S - - - SPP1 phage holin
HLLBMAHE_01510 3.73e-208 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HLLBMAHE_01512 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
HLLBMAHE_01513 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
HLLBMAHE_01514 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
HLLBMAHE_01515 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
HLLBMAHE_01516 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_01518 8.6e-308 steT - - E ko:K03294 - ko00000 amino acid
HLLBMAHE_01519 9.42e-232 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HLLBMAHE_01520 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLLBMAHE_01521 2.21e-229 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLBMAHE_01523 2.41e-284 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLLBMAHE_01524 1.16e-178 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
HLLBMAHE_01525 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
HLLBMAHE_01526 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLLBMAHE_01527 4.28e-224 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HLLBMAHE_01528 1.64e-237 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_01529 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
HLLBMAHE_01531 8.23e-226 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
HLLBMAHE_01532 1.14e-255 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
HLLBMAHE_01533 5.97e-209 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLLBMAHE_01534 4.88e-236 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_01535 1.34e-259 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
HLLBMAHE_01536 2.53e-205 ykgA - - E - - - Amidinotransferase
HLLBMAHE_01537 1.55e-119 ykhA - - I - - - Acyl-CoA hydrolase
HLLBMAHE_01538 5.35e-289 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HLLBMAHE_01539 1.15e-13 - - - - - - - -
HLLBMAHE_01540 3.25e-166 ykjA - - S - - - Protein of unknown function (DUF421)
HLLBMAHE_01541 5.07e-125 ykkA - - S - - - Protein of unknown function (DUF664)
HLLBMAHE_01542 3.59e-128 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLLBMAHE_01543 1.27e-72 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
HLLBMAHE_01544 1.36e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
HLLBMAHE_01545 5.81e-218 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HLLBMAHE_01546 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLLBMAHE_01547 1.6e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HLLBMAHE_01548 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
HLLBMAHE_01549 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
HLLBMAHE_01550 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
HLLBMAHE_01551 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
HLLBMAHE_01552 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HLLBMAHE_01553 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HLLBMAHE_01554 3.27e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLLBMAHE_01555 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
HLLBMAHE_01556 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_01557 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
HLLBMAHE_01558 1.21e-142 ykoF - - S - - - YKOF-related Family
HLLBMAHE_01559 1.28e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_01560 6.32e-309 ykoH - - T - - - Histidine kinase
HLLBMAHE_01561 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
HLLBMAHE_01562 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
HLLBMAHE_01563 1.45e-08 - - - - - - - -
HLLBMAHE_01565 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
HLLBMAHE_01566 1.49e-70 tnrA - - K - - - transcriptional
HLLBMAHE_01567 1.63e-25 - - - - - - - -
HLLBMAHE_01568 3.04e-36 ykoL - - - - - - -
HLLBMAHE_01569 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
HLLBMAHE_01570 1.09e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HLLBMAHE_01571 2.38e-127 ykoP - - G - - - polysaccharide deacetylase
HLLBMAHE_01572 9.84e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HLLBMAHE_01573 0.0 ykoS - - - - - - -
HLLBMAHE_01574 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLBMAHE_01575 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
HLLBMAHE_01576 1.25e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HLLBMAHE_01577 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
HLLBMAHE_01578 1.71e-143 ykoX - - S - - - membrane-associated protein
HLLBMAHE_01579 4.63e-227 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HLLBMAHE_01580 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_01581 9.93e-200 rsgI - - S - - - Anti-sigma factor N-terminus
HLLBMAHE_01582 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
HLLBMAHE_01583 1.55e-159 ykrK - - S - - - Domain of unknown function (DUF1836)
HLLBMAHE_01584 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
HLLBMAHE_01585 6.08e-309 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
HLLBMAHE_01587 1.77e-28 ykzE - - - - - - -
HLLBMAHE_01588 3.34e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
HLLBMAHE_01589 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_01590 7.91e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HLLBMAHE_01592 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HLLBMAHE_01593 1.67e-291 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HLLBMAHE_01594 1.99e-193 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HLLBMAHE_01595 7.65e-293 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLLBMAHE_01596 9.72e-295 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HLLBMAHE_01597 1.19e-173 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HLLBMAHE_01598 4.34e-145 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HLLBMAHE_01599 8.7e-123 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HLLBMAHE_01600 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
HLLBMAHE_01602 4.81e-94 eag - - - - - - -
HLLBMAHE_01603 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HLLBMAHE_01604 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
HLLBMAHE_01605 9.91e-170 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HLLBMAHE_01606 2.01e-178 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HLLBMAHE_01607 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
HLLBMAHE_01608 2.02e-228 ykvI - - S - - - membrane
HLLBMAHE_01609 6.42e-161 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HLLBMAHE_01610 4.03e-104 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
HLLBMAHE_01611 5.06e-179 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HLLBMAHE_01612 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HLLBMAHE_01613 9.79e-80 ykvN - - K - - - Transcriptional regulator
HLLBMAHE_01614 9.35e-173 ykvO - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HLLBMAHE_01615 2.67e-62 ykvR - - S - - - Protein of unknown function (DUF3219)
HLLBMAHE_01616 5.43e-35 ykvS - - S - - - protein conserved in bacteria
HLLBMAHE_01617 2.5e-39 - - - - - - - -
HLLBMAHE_01618 2.14e-140 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
HLLBMAHE_01619 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLLBMAHE_01620 5.79e-117 stoA - - CO - - - thiol-disulfide
HLLBMAHE_01621 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HLLBMAHE_01622 3.99e-09 - - - - - - - -
HLLBMAHE_01623 1.93e-264 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HLLBMAHE_01625 5.43e-229 ykvZ - - K - - - Transcriptional regulator
HLLBMAHE_01627 6.87e-168 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
HLLBMAHE_01628 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_01629 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
HLLBMAHE_01630 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HLLBMAHE_01631 6.27e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01632 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
HLLBMAHE_01633 1.52e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLBMAHE_01634 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_01635 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HLLBMAHE_01636 4.39e-17 vgb - - H ko:K18235 - ko00000,ko01000,ko01504 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
HLLBMAHE_01637 5.14e-170 ykwD - - J - - - protein with SCP PR1 domains
HLLBMAHE_01638 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HLLBMAHE_01639 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_01640 1.03e-283 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
HLLBMAHE_01641 1.05e-22 - - - - - - - -
HLLBMAHE_01642 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
HLLBMAHE_01643 3.71e-110 ykyB - - S - - - YkyB-like protein
HLLBMAHE_01644 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_01645 5.84e-115 ykuD - - S - - - protein conserved in bacteria
HLLBMAHE_01646 1.17e-210 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
HLLBMAHE_01647 2.13e-181 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_01648 7.16e-298 ykuI - - T - - - Diguanylate phosphodiesterase
HLLBMAHE_01649 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
HLLBMAHE_01650 3.73e-121 - - - S ko:K09776 - ko00000 Ribonuclease H-like
HLLBMAHE_01651 7.83e-38 ykzF - - S - - - Antirepressor AbbA
HLLBMAHE_01652 5.15e-100 ykuL - - S - - - CBS domain
HLLBMAHE_01653 6.52e-216 ccpC - - K - - - Transcriptional regulator
HLLBMAHE_01654 1.44e-109 - - - C ko:K03839 - ko00000 Flavodoxin domain
HLLBMAHE_01655 3.01e-223 ykuO - - - - - - -
HLLBMAHE_01656 1.03e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
HLLBMAHE_01657 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HLLBMAHE_01658 7.66e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HLLBMAHE_01659 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
HLLBMAHE_01660 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
HLLBMAHE_01661 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
HLLBMAHE_01662 2.45e-103 ykuV - - CO - - - thiol-disulfide
HLLBMAHE_01663 1.78e-120 rok - - K - - - Repressor of ComK
HLLBMAHE_01664 8.12e-199 yknT - - - ko:K06437 - ko00000 -
HLLBMAHE_01665 3.75e-141 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HLLBMAHE_01666 5.34e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HLLBMAHE_01667 4.29e-313 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
HLLBMAHE_01668 1.99e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
HLLBMAHE_01669 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
HLLBMAHE_01670 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HLLBMAHE_01671 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HLLBMAHE_01672 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
HLLBMAHE_01673 9.89e-146 yknW - - S - - - Yip1 domain
HLLBMAHE_01674 9.51e-233 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HLLBMAHE_01675 6.1e-160 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_01676 1.92e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HLLBMAHE_01677 4.29e-175 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01678 1.17e-214 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
HLLBMAHE_01679 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HLLBMAHE_01680 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLLBMAHE_01681 5.43e-52 ykoA - - - - - - -
HLLBMAHE_01682 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HLLBMAHE_01683 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_01684 2.35e-214 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLLBMAHE_01685 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
HLLBMAHE_01686 1.09e-18 - - - S - - - Uncharacterized protein YkpC
HLLBMAHE_01687 6.17e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
HLLBMAHE_01688 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
HLLBMAHE_01689 2.65e-306 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
HLLBMAHE_01690 8.06e-197 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
HLLBMAHE_01691 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HLLBMAHE_01692 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HLLBMAHE_01693 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLLBMAHE_01694 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
HLLBMAHE_01695 3.37e-186 ykrA - - S - - - hydrolases of the HAD superfamily
HLLBMAHE_01696 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLLBMAHE_01697 1.26e-07 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HLLBMAHE_01698 1.06e-138 ykyA - - L - - - Putative cell-wall binding lipoprotein
HLLBMAHE_01699 1.06e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLLBMAHE_01700 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLLBMAHE_01701 1.47e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLLBMAHE_01702 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLLBMAHE_01703 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
HLLBMAHE_01704 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
HLLBMAHE_01705 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
HLLBMAHE_01706 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
HLLBMAHE_01707 2.03e-35 ykzI - - - - - - -
HLLBMAHE_01708 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
HLLBMAHE_01709 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
HLLBMAHE_01710 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HLLBMAHE_01711 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
HLLBMAHE_01712 0.0 ylaA - - - - - - -
HLLBMAHE_01713 1.44e-56 ylaB - - - - - - -
HLLBMAHE_01714 4.16e-114 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_01716 1.74e-57 ylaE - - - - - - -
HLLBMAHE_01717 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
HLLBMAHE_01718 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
HLLBMAHE_01719 8.88e-63 ylaH - - S - - - YlaH-like protein
HLLBMAHE_01720 8.92e-44 ylaI - - S - - - protein conserved in bacteria
HLLBMAHE_01721 1.64e-124 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLLBMAHE_01722 3.76e-316 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
HLLBMAHE_01723 1.09e-110 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HLLBMAHE_01724 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
HLLBMAHE_01725 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
HLLBMAHE_01726 7.05e-271 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HLLBMAHE_01727 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HLLBMAHE_01728 4.72e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HLLBMAHE_01729 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HLLBMAHE_01730 2.38e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HLLBMAHE_01731 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLLBMAHE_01732 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HLLBMAHE_01733 6.09e-70 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HLLBMAHE_01734 1.21e-213 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
HLLBMAHE_01735 1.61e-81 ylbA - - S - - - YugN-like family
HLLBMAHE_01736 1.08e-97 ylbB - - T - - - COG0517 FOG CBS domain
HLLBMAHE_01737 3.61e-255 ylbC - - S - - - protein with SCP PR1 domains
HLLBMAHE_01738 2.66e-88 ylbD - - S - - - Putative coat protein
HLLBMAHE_01739 1.73e-48 ylbE - - S - - - YlbE-like protein
HLLBMAHE_01740 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
HLLBMAHE_01741 4.36e-52 ylbG - - S - - - UPF0298 protein
HLLBMAHE_01742 6.07e-126 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
HLLBMAHE_01743 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HLLBMAHE_01744 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
HLLBMAHE_01745 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HLLBMAHE_01746 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
HLLBMAHE_01747 1.75e-293 ylbM - - S - - - Belongs to the UPF0348 family
HLLBMAHE_01749 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
HLLBMAHE_01750 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
HLLBMAHE_01751 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HLLBMAHE_01752 1.33e-115 ylbP - - K - - - n-acetyltransferase
HLLBMAHE_01753 1.66e-216 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HLLBMAHE_01754 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HLLBMAHE_01755 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
HLLBMAHE_01756 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HLLBMAHE_01757 3.42e-68 ftsL - - D - - - Essential cell division protein
HLLBMAHE_01758 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
HLLBMAHE_01759 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
HLLBMAHE_01760 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HLLBMAHE_01761 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HLLBMAHE_01762 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HLLBMAHE_01763 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
HLLBMAHE_01764 7.74e-257 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HLLBMAHE_01765 3.74e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
HLLBMAHE_01766 1.18e-178 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HLLBMAHE_01767 1.35e-143 ylxW - - S - - - protein conserved in bacteria
HLLBMAHE_01768 6.11e-132 ylxX - - S - - - protein conserved in bacteria
HLLBMAHE_01769 5.37e-76 sbp - - S - - - small basic protein
HLLBMAHE_01770 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HLLBMAHE_01771 2.61e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HLLBMAHE_01772 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
HLLBMAHE_01774 1.17e-217 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HLLBMAHE_01775 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_01776 7.99e-180 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_01777 4.49e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HLLBMAHE_01778 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
HLLBMAHE_01779 3.58e-51 ylmC - - S - - - sporulation protein
HLLBMAHE_01780 1.07e-202 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
HLLBMAHE_01781 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HLLBMAHE_01782 4.47e-87 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HLLBMAHE_01783 1.22e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
HLLBMAHE_01784 1.49e-178 ylmH - - S - - - conserved protein, contains S4-like domain
HLLBMAHE_01785 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
HLLBMAHE_01786 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HLLBMAHE_01787 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
HLLBMAHE_01788 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HLLBMAHE_01789 2.04e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
HLLBMAHE_01790 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HLLBMAHE_01791 7.45e-296 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
HLLBMAHE_01792 4.4e-215 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
HLLBMAHE_01793 0.0 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HLLBMAHE_01794 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
HLLBMAHE_01795 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
HLLBMAHE_01796 7.44e-183 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HLLBMAHE_01797 7.36e-222 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HLLBMAHE_01798 6.56e-164 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HLLBMAHE_01799 8.96e-149 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HLLBMAHE_01801 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
HLLBMAHE_01802 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
HLLBMAHE_01803 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
HLLBMAHE_01804 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
HLLBMAHE_01805 6.89e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
HLLBMAHE_01806 3.56e-188 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
HLLBMAHE_01807 9.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
HLLBMAHE_01808 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
HLLBMAHE_01809 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
HLLBMAHE_01810 8.41e-202 yloC - - S - - - stress-induced protein
HLLBMAHE_01811 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
HLLBMAHE_01812 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
HLLBMAHE_01813 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HLLBMAHE_01814 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HLLBMAHE_01815 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HLLBMAHE_01816 2.38e-109 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HLLBMAHE_01817 2.21e-226 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HLLBMAHE_01818 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HLLBMAHE_01819 5.3e-264 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HLLBMAHE_01820 3.54e-180 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
HLLBMAHE_01821 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
HLLBMAHE_01822 4.57e-214 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HLLBMAHE_01823 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
HLLBMAHE_01824 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
HLLBMAHE_01825 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
HLLBMAHE_01826 3.65e-78 yloU - - S - - - protein conserved in bacteria
HLLBMAHE_01827 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
HLLBMAHE_01828 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HLLBMAHE_01829 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
HLLBMAHE_01830 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HLLBMAHE_01831 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HLLBMAHE_01832 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HLLBMAHE_01833 3.09e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
HLLBMAHE_01834 1.17e-165 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
HLLBMAHE_01835 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
HLLBMAHE_01836 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HLLBMAHE_01837 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
HLLBMAHE_01838 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HLLBMAHE_01839 1.67e-114 - - - - - - - -
HLLBMAHE_01840 8.01e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HLLBMAHE_01841 3.95e-308 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HLLBMAHE_01842 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
HLLBMAHE_01843 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
HLLBMAHE_01844 9.77e-80 ylqD - - S - - - YlqD protein
HLLBMAHE_01845 1.84e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HLLBMAHE_01846 9.8e-177 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
HLLBMAHE_01847 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HLLBMAHE_01848 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HLLBMAHE_01849 1.95e-173 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLLBMAHE_01850 0.0 ylqG - - - - - - -
HLLBMAHE_01851 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
HLLBMAHE_01852 1.94e-268 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HLLBMAHE_01853 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HLLBMAHE_01854 5.15e-215 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
HLLBMAHE_01855 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HLLBMAHE_01856 5.45e-314 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HLLBMAHE_01857 1.13e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
HLLBMAHE_01858 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HLLBMAHE_01859 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HLLBMAHE_01860 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HLLBMAHE_01861 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HLLBMAHE_01862 8.81e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
HLLBMAHE_01863 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
HLLBMAHE_01864 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
HLLBMAHE_01865 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLLBMAHE_01866 9.09e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
HLLBMAHE_01867 1.59e-303 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HLLBMAHE_01868 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
HLLBMAHE_01869 1.51e-78 ylxF - - S - - - MgtE intracellular N domain
HLLBMAHE_01870 3.04e-303 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
HLLBMAHE_01871 2.81e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
HLLBMAHE_01872 1.66e-174 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
HLLBMAHE_01873 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
HLLBMAHE_01874 2.21e-229 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HLLBMAHE_01875 1.38e-253 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HLLBMAHE_01876 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
HLLBMAHE_01877 1.3e-135 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
HLLBMAHE_01878 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
HLLBMAHE_01879 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
HLLBMAHE_01880 6.98e-169 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
HLLBMAHE_01881 7.85e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLLBMAHE_01882 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HLLBMAHE_01883 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
HLLBMAHE_01884 3.14e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
HLLBMAHE_01885 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HLLBMAHE_01886 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
HLLBMAHE_01887 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
HLLBMAHE_01888 5.06e-144 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HLLBMAHE_01889 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HLLBMAHE_01890 1.33e-175 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_01891 4.66e-99 ylxL - - - - - - -
HLLBMAHE_01892 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
HLLBMAHE_01893 2.81e-201 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HLLBMAHE_01894 2.37e-162 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
HLLBMAHE_01895 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HLLBMAHE_01896 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HLLBMAHE_01897 5.77e-179 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
HLLBMAHE_01898 1.39e-276 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HLLBMAHE_01899 4.72e-285 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
HLLBMAHE_01900 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HLLBMAHE_01901 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HLLBMAHE_01903 1.2e-157 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
HLLBMAHE_01904 5.12e-144 - - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC superfamily ATP binding cassette transporter, ABC
HLLBMAHE_01905 2.24e-58 - - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 PFAM Lanthionine synthetase
HLLBMAHE_01906 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
HLLBMAHE_01907 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
HLLBMAHE_01908 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
HLLBMAHE_01909 6.16e-63 ylxQ - - J - - - ribosomal protein
HLLBMAHE_01910 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HLLBMAHE_01911 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
HLLBMAHE_01912 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HLLBMAHE_01913 2.46e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HLLBMAHE_01914 3.84e-231 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
HLLBMAHE_01915 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HLLBMAHE_01916 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HLLBMAHE_01917 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
HLLBMAHE_01918 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
HLLBMAHE_01919 1.53e-56 ymxH - - S - - - YlmC YmxH family
HLLBMAHE_01920 5.3e-208 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
HLLBMAHE_01921 8.17e-141 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HLLBMAHE_01922 6.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HLLBMAHE_01923 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HLLBMAHE_01924 6.39e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HLLBMAHE_01925 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HLLBMAHE_01926 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
HLLBMAHE_01927 4.94e-44 - - - S - - - YlzJ-like protein
HLLBMAHE_01928 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HLLBMAHE_01929 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_01930 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_01931 1.1e-297 albE - - S - - - Peptidase M16
HLLBMAHE_01932 2.37e-309 ymfH - - S - - - zinc protease
HLLBMAHE_01933 1.49e-166 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HLLBMAHE_01934 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
HLLBMAHE_01935 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
HLLBMAHE_01936 3.05e-177 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
HLLBMAHE_01937 1.12e-130 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HLLBMAHE_01938 1.06e-299 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
HLLBMAHE_01939 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HLLBMAHE_01940 2.32e-279 pbpX - - V - - - Beta-lactamase
HLLBMAHE_01941 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
HLLBMAHE_01942 6.18e-195 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
HLLBMAHE_01943 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
HLLBMAHE_01944 2.78e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HLLBMAHE_01945 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLLBMAHE_01946 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HLLBMAHE_01947 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
HLLBMAHE_01948 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
HLLBMAHE_01949 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HLLBMAHE_01950 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HLLBMAHE_01951 1.98e-90 - - - S - - - Regulatory protein YrvL
HLLBMAHE_01952 5.38e-125 ymcC - - S - - - Membrane
HLLBMAHE_01953 2.79e-132 pksA - - K - - - Transcriptional regulator
HLLBMAHE_01954 8.03e-81 ymzB - - - - - - -
HLLBMAHE_01955 1.54e-206 - - - S - - - Metallo-beta-lactamase superfamily
HLLBMAHE_01956 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
HLLBMAHE_01958 3.96e-163 ymaC - - S - - - Replication protein
HLLBMAHE_01959 5.98e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
HLLBMAHE_01960 6.39e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
HLLBMAHE_01961 2.02e-66 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HLLBMAHE_01963 5.41e-76 ymaF - - S - - - YmaF family
HLLBMAHE_01964 1.38e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HLLBMAHE_01965 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HLLBMAHE_01966 1.63e-31 - - - - - - - -
HLLBMAHE_01967 1.2e-30 ymzA - - - - - - -
HLLBMAHE_01968 8.31e-65 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
HLLBMAHE_01969 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLBMAHE_01970 3.34e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLBMAHE_01971 2.61e-140 - - - - - - - -
HLLBMAHE_01972 2.23e-147 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HLLBMAHE_01973 1.33e-225 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
HLLBMAHE_01974 6.07e-292 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HLLBMAHE_01975 1.67e-310 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HLLBMAHE_01976 4.05e-89 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
HLLBMAHE_01977 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
HLLBMAHE_01978 1.65e-47 - - - L - - - Arm DNA-binding domain
HLLBMAHE_01979 1.95e-101 - 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 replicative DNA helicase
HLLBMAHE_01981 5.55e-67 - - - M - - - ArpU family transcriptional regulator
HLLBMAHE_01982 6.41e-21 - - - S - - - PFAM FRG domain
HLLBMAHE_01983 1.14e-64 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
HLLBMAHE_01984 9.51e-26 - - - - - - - -
HLLBMAHE_01986 1.41e-84 - - - Q - - - Collagen triple helix repeat (20 copies)
HLLBMAHE_01987 3.9e-119 - - - M - - - Glycosyltransferase like family
HLLBMAHE_01988 5.8e-156 - - - H - - - Methionine biosynthesis protein MetW
HLLBMAHE_01989 2.03e-246 - - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLBMAHE_01990 1.28e-273 - - - H - - - N-terminal domain of galactosyltransferase
HLLBMAHE_01991 3.38e-125 ynaD - - J - - - Acetyltransferase (GNAT) domain
HLLBMAHE_01993 1.21e-90 - - - S - - - CAAX protease self-immunity
HLLBMAHE_01994 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HLLBMAHE_01995 9.72e-31 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HLLBMAHE_01996 5.26e-152 - - - S - - - Domain of unknown function (DUF3885)
HLLBMAHE_01997 2.36e-53 ynaF - - - - - - -
HLLBMAHE_01999 5.23e-102 - - - E - - - phosphoribosylanthranilate isomerase activity
HLLBMAHE_02000 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
HLLBMAHE_02001 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HLLBMAHE_02002 3.15e-278 xylR - - GK - - - ROK family
HLLBMAHE_02003 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
HLLBMAHE_02004 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
HLLBMAHE_02005 4.16e-144 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HLLBMAHE_02006 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_02007 2.51e-280 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HLLBMAHE_02008 2.24e-106 - - - S - - - Protein of unknown function (DUF2691)
HLLBMAHE_02009 3.51e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HLLBMAHE_02012 1.12e-209 - - - S - - - Thymidylate synthase
HLLBMAHE_02014 2.46e-169 - - - S - - - Domain of unknown function, YrpD
HLLBMAHE_02017 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
HLLBMAHE_02018 1.04e-94 - - - - - - - -
HLLBMAHE_02020 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_02021 1.81e-103 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
HLLBMAHE_02024 0.0 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HLLBMAHE_02025 1.26e-246 yndE7 - - U ko:K06311 - ko00000,ko02000 Spore germination
HLLBMAHE_02026 3.09e-286 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
HLLBMAHE_02027 2.07e-195 yndG - - S - - - DoxX-like family
HLLBMAHE_02028 2e-148 - - - S - - - Domain of unknown function (DUF4166)
HLLBMAHE_02029 0.0 yndJ - - S - - - YndJ-like protein
HLLBMAHE_02031 6.31e-173 yndL - - S - - - Replication protein
HLLBMAHE_02032 7.41e-120 yndM - - S - - - Protein of unknown function (DUF2512)
HLLBMAHE_02033 1.74e-101 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HLLBMAHE_02034 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HLLBMAHE_02035 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HLLBMAHE_02036 3.97e-145 yneB - - L - - - resolvase
HLLBMAHE_02037 1.15e-43 ynzC - - S - - - UPF0291 protein
HLLBMAHE_02038 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HLLBMAHE_02039 6.25e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
HLLBMAHE_02040 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
HLLBMAHE_02041 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
HLLBMAHE_02042 1.18e-164 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
HLLBMAHE_02043 2.12e-77 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
HLLBMAHE_02044 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
HLLBMAHE_02045 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
HLLBMAHE_02046 3.34e-84 cotM - - O ko:K06335 - ko00000 Spore coat protein
HLLBMAHE_02047 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
HLLBMAHE_02048 3.27e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
HLLBMAHE_02049 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HLLBMAHE_02050 7.25e-118 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HLLBMAHE_02051 9.26e-10 - - - S - - - Fur-regulated basic protein B
HLLBMAHE_02053 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
HLLBMAHE_02054 4.02e-95 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
HLLBMAHE_02055 4.68e-71 yneQ - - - - - - -
HLLBMAHE_02056 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
HLLBMAHE_02057 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HLLBMAHE_02058 1.21e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
HLLBMAHE_02059 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLLBMAHE_02060 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HLLBMAHE_02061 1.82e-18 - - - - - - - -
HLLBMAHE_02062 8.74e-75 ynfC - - - - - - -
HLLBMAHE_02063 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
HLLBMAHE_02064 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
HLLBMAHE_02066 1.97e-316 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
HLLBMAHE_02067 0.0 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
HLLBMAHE_02068 1.72e-103 yngA - - S - - - membrane
HLLBMAHE_02069 1.3e-208 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HLLBMAHE_02070 2.01e-134 yngC - - S - - - membrane-associated protein
HLLBMAHE_02071 7.39e-296 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
HLLBMAHE_02072 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLLBMAHE_02073 6.03e-175 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
HLLBMAHE_02074 1.93e-211 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
HLLBMAHE_02075 2.4e-41 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
HLLBMAHE_02076 9.36e-317 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
HLLBMAHE_02077 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLLBMAHE_02078 1.26e-266 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HLLBMAHE_02079 7.53e-32 - - - S - - - Family of unknown function (DUF5367)
HLLBMAHE_02080 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
HLLBMAHE_02081 2.48e-83 yngL - - S - - - Protein of unknown function (DUF1360)
HLLBMAHE_02082 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
HLLBMAHE_02083 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_02084 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_02085 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
HLLBMAHE_02086 1.45e-235 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
HLLBMAHE_02087 9.8e-313 yoeA - - V - - - MATE efflux family protein
HLLBMAHE_02088 2.91e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
HLLBMAHE_02090 9.36e-124 - - - L - - - Integrase
HLLBMAHE_02091 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
HLLBMAHE_02092 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HLLBMAHE_02093 1.69e-198 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_02094 2.11e-210 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HLLBMAHE_02095 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HLLBMAHE_02096 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
HLLBMAHE_02097 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_02098 9.09e-260 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HLLBMAHE_02099 1.58e-184 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLLBMAHE_02100 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HLLBMAHE_02101 2.28e-159 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_02102 4.86e-54 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
HLLBMAHE_02103 4.25e-173 yoxB - - - - - - -
HLLBMAHE_02104 3.84e-121 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HLLBMAHE_02105 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
HLLBMAHE_02106 0.0 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
HLLBMAHE_02107 1.31e-231 yoaD 1.1.1.399, 1.1.1.95 - EH ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLLBMAHE_02108 0.0 yoaE - - C - - - belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLLBMAHE_02109 1.2e-43 yoaF - - - - - - -
HLLBMAHE_02111 6.04e-55 - - - S - - - Protein of unknown function (DUF4025)
HLLBMAHE_02112 3.67e-230 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HLLBMAHE_02113 4.9e-37 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
HLLBMAHE_02114 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
HLLBMAHE_02115 2.61e-171 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
HLLBMAHE_02116 1.79e-145 yoaK - - S - - - Membrane
HLLBMAHE_02117 8.29e-252 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
HLLBMAHE_02118 3.43e-169 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HLLBMAHE_02121 2.97e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HLLBMAHE_02124 2.09e-110 - - - - - - - -
HLLBMAHE_02125 9.34e-190 yoaR - - V - - - vancomycin resistance protein
HLLBMAHE_02126 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
HLLBMAHE_02127 1.21e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_02128 1.63e-190 yoaT - - S - - - Protein of unknown function (DUF817)
HLLBMAHE_02129 6.67e-203 yoaU - - K - - - LysR substrate binding domain
HLLBMAHE_02130 1.11e-202 yoaV - - EG - - - EamA-like transporter family
HLLBMAHE_02131 3.38e-71 yoaW - - - - - - -
HLLBMAHE_02132 3.44e-15 yoaW - - - - - - -
HLLBMAHE_02133 2.07e-148 lin0465 - - S - - - DJ-1/PfpI family
HLLBMAHE_02134 8.16e-212 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
HLLBMAHE_02137 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
HLLBMAHE_02138 7.53e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
HLLBMAHE_02139 7.35e-17 - - - - - - - -
HLLBMAHE_02146 5.11e-96 - - - S - - - Domain of unknown function (DUF4062)
HLLBMAHE_02147 1.72e-94 - - - S - - - Domain of unknown function (DUF4062)
HLLBMAHE_02148 2.87e-43 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HLLBMAHE_02149 4.31e-44 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 photosystem II stabilization
HLLBMAHE_02150 4.81e-152 - - - O - - - Subtilase family
HLLBMAHE_02151 1.23e-134 - - - - - - - -
HLLBMAHE_02152 3.23e-86 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
HLLBMAHE_02153 9.95e-23 - - - - - - - -
HLLBMAHE_02156 8.56e-119 - - - S ko:K21490 - ko00000,ko02048 SMI1 / KNR4 family (SUKH-1)
HLLBMAHE_02157 2.12e-64 - - - UW ko:K21487,ko:K21489,ko:K21491,ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HLLBMAHE_02158 2.34e-284 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HLLBMAHE_02159 1.81e-108 yokH - - G - - - SMI1 / KNR4 family
HLLBMAHE_02160 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
HLLBMAHE_02161 1.75e-69 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
HLLBMAHE_02162 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
HLLBMAHE_02163 1.34e-176 - - - J - - - FR47-like protein
HLLBMAHE_02164 1.53e-127 yobS - - K - - - Transcriptional regulator
HLLBMAHE_02165 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HLLBMAHE_02166 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
HLLBMAHE_02167 2.76e-220 yobV - - K - - - WYL domain
HLLBMAHE_02168 6.07e-120 yobW - - - - - - -
HLLBMAHE_02169 2.72e-67 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
HLLBMAHE_02170 9.39e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLLBMAHE_02171 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
HLLBMAHE_02172 2.6e-185 - - - - - - - -
HLLBMAHE_02173 2.19e-121 yocC - - - - - - -
HLLBMAHE_02174 2.25e-239 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
HLLBMAHE_02175 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
HLLBMAHE_02176 1.74e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_02177 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_02178 2.89e-175 yocH - - M - - - COG1388 FOG LysM repeat
HLLBMAHE_02179 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HLLBMAHE_02180 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLLBMAHE_02181 1.42e-107 yocK - - T - - - general stress protein
HLLBMAHE_02182 3.02e-70 yocL - - - - - - -
HLLBMAHE_02183 2.02e-43 - - - - - - - -
HLLBMAHE_02184 2.69e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLLBMAHE_02185 2.94e-55 yozN - - - - - - -
HLLBMAHE_02186 1.83e-49 yocN - - - - - - -
HLLBMAHE_02187 2.17e-74 yozO - - S - - - Bacterial PH domain
HLLBMAHE_02188 1.91e-42 yozC - - - - - - -
HLLBMAHE_02189 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HLLBMAHE_02190 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
HLLBMAHE_02191 3.91e-211 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
HLLBMAHE_02192 1.45e-298 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HLLBMAHE_02193 1.11e-212 yocS - - S ko:K03453 - ko00000 -transporter
HLLBMAHE_02194 3.16e-265 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HLLBMAHE_02195 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HLLBMAHE_02196 0.0 yojO - - P - - - Von Willebrand factor
HLLBMAHE_02197 4.45e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
HLLBMAHE_02198 7.31e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HLLBMAHE_02199 1.07e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
HLLBMAHE_02200 9.32e-293 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
HLLBMAHE_02201 3.54e-140 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HLLBMAHE_02203 4.85e-312 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
HLLBMAHE_02204 2.05e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLLBMAHE_02205 3.71e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
HLLBMAHE_02206 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
HLLBMAHE_02207 1.85e-58 - - - - - - - -
HLLBMAHE_02208 1.92e-206 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
HLLBMAHE_02209 2.88e-103 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
HLLBMAHE_02210 5.59e-14 - - - - - - - -
HLLBMAHE_02211 1.59e-75 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HLLBMAHE_02212 1.67e-184 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HLLBMAHE_02213 1.14e-83 iolK - - S - - - tautomerase
HLLBMAHE_02214 2.63e-73 yodB - - K - - - transcriptional
HLLBMAHE_02215 1.11e-139 yodC - - C - - - nitroreductase
HLLBMAHE_02216 4.39e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
HLLBMAHE_02217 4.8e-223 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
HLLBMAHE_02218 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
HLLBMAHE_02219 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLLBMAHE_02220 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HLLBMAHE_02221 7.15e-165 yodH - - Q - - - Methyltransferase
HLLBMAHE_02222 4.86e-41 yodI - - - - - - -
HLLBMAHE_02223 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
HLLBMAHE_02224 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
HLLBMAHE_02225 2.08e-12 - - - - - - - -
HLLBMAHE_02226 1.17e-71 yodL - - S - - - YodL-like
HLLBMAHE_02227 4.02e-138 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
HLLBMAHE_02228 5.18e-34 yozD - - S - - - YozD-like protein
HLLBMAHE_02230 1.75e-157 yodN - - - - - - -
HLLBMAHE_02231 7.3e-50 yozE - - S - - - Belongs to the UPF0346 family
HLLBMAHE_02232 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
HLLBMAHE_02233 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
HLLBMAHE_02234 5.27e-197 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
HLLBMAHE_02235 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
HLLBMAHE_02236 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLLBMAHE_02237 1.97e-160 atoD 2.8.3.8, 2.8.3.9 - I ko:K01034 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLLBMAHE_02238 9.36e-317 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HLLBMAHE_02241 2.65e-137 - - - L - - - Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLLBMAHE_02248 3.1e-214 - - - S - - - Calcineurin-like phosphoesterase
HLLBMAHE_02249 2.24e-41 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HLLBMAHE_02250 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_02253 8.14e-203 - - - S - - - Thymidylate synthase
HLLBMAHE_02256 1.9e-20 XK27_09885 - - V - - - COG4767 Glycopeptide antibiotics resistance protein
HLLBMAHE_02257 4.25e-97 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
HLLBMAHE_02258 3.33e-51 - - - O - - - Glutaredoxin
HLLBMAHE_02259 6.84e-85 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLBMAHE_02261 7.53e-123 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLBMAHE_02263 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLBMAHE_02264 2.43e-44 - - - L - - - GIY-YIG catalytic domain
HLLBMAHE_02265 1.41e-174 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HLLBMAHE_02266 2.28e-84 - - - S - - - NrdI Flavodoxin like
HLLBMAHE_02275 1.29e-14 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
HLLBMAHE_02285 4.55e-105 tmk 2.1.1.45, 2.7.4.9 - F ko:K00560,ko:K00943 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 dTDP biosynthetic process
HLLBMAHE_02290 1.52e-149 - - - S - - - protein conserved in bacteria
HLLBMAHE_02291 0.0 - 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HLLBMAHE_02292 0.0 - - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HLLBMAHE_02293 4.7e-286 - - - L - - - DNA primase activity
HLLBMAHE_02294 0.0 - - - J - - - DnaB-like helicase C terminal domain
HLLBMAHE_02295 2.14e-110 - - - - - - - -
HLLBMAHE_02296 6.35e-229 - - - L - - - AAA domain
HLLBMAHE_02297 1.27e-198 - - - - - - - -
HLLBMAHE_02303 1.02e-164 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
HLLBMAHE_02304 4.82e-186 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 - L ko:K01971,ko:K10747 ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450 ko00000,ko00001,ko01000,ko03032,ko03400 ATP-dependent DNA ligase
HLLBMAHE_02305 2.83e-99 - - - - - - - -
HLLBMAHE_02307 7.6e-106 dut 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 deoxyuridine 5'-triphosphate nucleotidohydrolase
HLLBMAHE_02311 1.65e-52 - - - - - - - -
HLLBMAHE_02312 1.56e-64 - - - S - - - Protein of unknown function (DUF1273)
HLLBMAHE_02318 0.000166 - - - S - - - YopX protein
HLLBMAHE_02323 4.78e-46 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_02324 2.89e-226 - - - - - - - -
HLLBMAHE_02325 0.0 - - - S - - - DNA-sulfur modification-associated
HLLBMAHE_02326 2.04e-254 - - - L - - - Belongs to the 'phage' integrase family
HLLBMAHE_02331 4.56e-134 - - - - - - - -
HLLBMAHE_02333 7.9e-19 - - - - - - - -
HLLBMAHE_02334 6e-26 - - - - - - - -
HLLBMAHE_02339 5.78e-68 - - - - - - - -
HLLBMAHE_02340 6.06e-94 - - - S - - - Domain of unknown function (DUF4062)
HLLBMAHE_02341 2.36e-42 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HLLBMAHE_02342 4.98e-106 yoaW - - - - - - -
HLLBMAHE_02343 9.59e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HLLBMAHE_02344 5.43e-69 - - - S - - - Bacteriophage abortive infection AbiH
HLLBMAHE_02351 1.81e-261 - - - - - - - -
HLLBMAHE_02352 1.2e-05 - - - - - - - -
HLLBMAHE_02353 3.04e-54 - - - - - - - -
HLLBMAHE_02356 0.0 - - - - - - - -
HLLBMAHE_02357 5.12e-06 - - - S - - - nucleic acid binding
HLLBMAHE_02358 2.21e-94 - - - - - - - -
HLLBMAHE_02359 3.5e-47 - - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLLBMAHE_02361 2.26e-267 - - - S - - - Calcineurin-like phosphoesterase superfamily domain
HLLBMAHE_02363 8.62e-223 - - - - - - - -
HLLBMAHE_02364 0.0 - - - S - - - Terminase-like family
HLLBMAHE_02365 0.0 - - - - - - - -
HLLBMAHE_02366 0.0 - - - - - - - -
HLLBMAHE_02367 1.02e-121 - - - - - - - -
HLLBMAHE_02368 3.43e-236 - - - - - - - -
HLLBMAHE_02369 2.31e-105 - - - - - - - -
HLLBMAHE_02370 5.6e-85 - - - - - - - -
HLLBMAHE_02372 1.51e-153 - - - - - - - -
HLLBMAHE_02373 1.47e-116 - - - - - - - -
HLLBMAHE_02374 2.4e-169 - - - - - - - -
HLLBMAHE_02375 4.32e-143 - - - - - - - -
HLLBMAHE_02378 1.1e-69 - - - - - - - -
HLLBMAHE_02379 4.21e-10 - - - - - - - -
HLLBMAHE_02380 1.13e-50 - - - - - - - -
HLLBMAHE_02382 7.26e-107 - - - - - - - -
HLLBMAHE_02383 3.29e-84 - - - - - - - -
HLLBMAHE_02384 8.92e-154 - - - L - - - Belongs to the 'phage' integrase family
HLLBMAHE_02386 1.27e-65 - - - - - - - -
HLLBMAHE_02387 0.0 - - - S - - - peptidoglycan catabolic process
HLLBMAHE_02388 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_02389 0.0 - - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HLLBMAHE_02390 5.69e-185 - - - S - - - Phage tail protein
HLLBMAHE_02391 0.0 - - - S - - - Pfam Transposase IS66
HLLBMAHE_02392 2.01e-144 - - - - - - - -
HLLBMAHE_02393 2.16e-53 - - - - - - - -
HLLBMAHE_02395 7.56e-12 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
HLLBMAHE_02396 7.29e-111 - - - S - - - N-acetylmuramoyl-L-alanine amidase activity
HLLBMAHE_02398 4.83e-50 - - - S - - - Bacteriophage holin
HLLBMAHE_02399 1.29e-133 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HLLBMAHE_02401 6.52e-95 - - - - - - - -
HLLBMAHE_02402 2.95e-151 - - - J - - - tRNA cytidylyltransferase activity
HLLBMAHE_02403 8.72e-297 - - - S - - - damaged DNA binding
HLLBMAHE_02404 4.13e-68 - - - S - - - YolD-like protein
HLLBMAHE_02405 1.36e-53 - - - - - - - -
HLLBMAHE_02408 2.83e-104 - - - S - - - SMI1-KNR4 cell-wall
HLLBMAHE_02409 5.39e-216 - - - S - - - Bacterial EndoU nuclease
HLLBMAHE_02410 5.78e-167 - - - V - - - HNH endonuclease
HLLBMAHE_02411 7.8e-87 - - - G - - - SMI1-KNR4 cell-wall
HLLBMAHE_02412 9.4e-48 - - - - - - - -
HLLBMAHE_02413 6.77e-167 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
HLLBMAHE_02414 3.21e-104 - - - S ko:K03824 - ko00000,ko01000 family acetyltransferase
HLLBMAHE_02418 3.56e-301 yokA - - L - - - Recombinase
HLLBMAHE_02419 1.02e-123 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HLLBMAHE_02420 4.13e-102 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
HLLBMAHE_02421 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HLLBMAHE_02422 4.14e-94 ypoP - - K - - - transcriptional
HLLBMAHE_02423 9.99e-290 mepA - - V - - - MATE efflux family protein
HLLBMAHE_02424 8.69e-40 ypmT - - S - - - Uncharacterized ympT
HLLBMAHE_02425 1.95e-128 ypmS - - S - - - protein conserved in bacteria
HLLBMAHE_02426 1.28e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
HLLBMAHE_02427 2.77e-140 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HLLBMAHE_02428 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
HLLBMAHE_02429 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HLLBMAHE_02430 5.7e-236 yplP - - K - - - Transcriptional regulator
HLLBMAHE_02431 8.03e-143 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
HLLBMAHE_02432 6.96e-145 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HLLBMAHE_02433 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HLLBMAHE_02434 6.98e-201 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HLLBMAHE_02435 8.91e-121 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HLLBMAHE_02436 3.47e-148 ypjP - - S - - - YpjP-like protein
HLLBMAHE_02437 6.15e-187 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
HLLBMAHE_02438 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
HLLBMAHE_02439 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
HLLBMAHE_02440 6.98e-205 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
HLLBMAHE_02441 1.91e-137 yagB - - S ko:K06950 - ko00000 phosphohydrolase
HLLBMAHE_02442 1.05e-112 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
HLLBMAHE_02443 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HLLBMAHE_02444 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HLLBMAHE_02445 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
HLLBMAHE_02446 1.17e-22 degR - - - - - - -
HLLBMAHE_02447 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
HLLBMAHE_02448 1.29e-40 ypeQ - - S - - - Zinc-finger
HLLBMAHE_02449 3.16e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
HLLBMAHE_02450 3.27e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HLLBMAHE_02451 6.28e-87 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
HLLBMAHE_02452 5.23e-05 - - - - ko:K06429 - ko00000 -
HLLBMAHE_02453 2.26e-213 ypcP - - L - - - 5'3' exonuclease
HLLBMAHE_02454 1.08e-11 - - - - - - - -
HLLBMAHE_02455 6.77e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
HLLBMAHE_02456 0.0 ypbR - - S - - - Dynamin family
HLLBMAHE_02457 3.33e-113 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
HLLBMAHE_02458 2.63e-265 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
HLLBMAHE_02459 2.03e-290 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HLLBMAHE_02460 5.51e-127 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HLLBMAHE_02461 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HLLBMAHE_02462 4.09e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HLLBMAHE_02463 1.2e-131 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
HLLBMAHE_02464 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
HLLBMAHE_02465 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
HLLBMAHE_02466 2.96e-203 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HLLBMAHE_02467 4.63e-176 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_02468 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_02469 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
HLLBMAHE_02471 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
HLLBMAHE_02472 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HLLBMAHE_02473 3.41e-128 ypsA - - S - - - Belongs to the UPF0398 family
HLLBMAHE_02474 7.21e-301 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
HLLBMAHE_02475 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HLLBMAHE_02476 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
HLLBMAHE_02477 1.02e-93 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
HLLBMAHE_02478 8.72e-68 yppG - - S - - - YppG-like protein
HLLBMAHE_02479 9.21e-11 - - - S - - - YppF-like protein
HLLBMAHE_02480 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
HLLBMAHE_02483 1.7e-236 yppC - - S - - - Protein of unknown function (DUF2515)
HLLBMAHE_02484 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HLLBMAHE_02485 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HLLBMAHE_02486 4.78e-120 ypoC - - - - - - -
HLLBMAHE_02487 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HLLBMAHE_02488 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
HLLBMAHE_02489 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
HLLBMAHE_02490 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
HLLBMAHE_02491 2.66e-102 ypmB - - S - - - protein conserved in bacteria
HLLBMAHE_02492 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
HLLBMAHE_02493 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
HLLBMAHE_02494 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HLLBMAHE_02495 3.69e-198 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HLLBMAHE_02496 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HLLBMAHE_02497 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HLLBMAHE_02498 4.32e-278 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HLLBMAHE_02499 8.18e-266 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
HLLBMAHE_02500 1.89e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
HLLBMAHE_02501 1.03e-92 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
HLLBMAHE_02502 3.98e-188 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HLLBMAHE_02503 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
HLLBMAHE_02504 1.51e-199 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HLLBMAHE_02505 2.79e-182 ypjB - - S - - - sporulation protein
HLLBMAHE_02506 1.98e-126 ypjA - - S - - - membrane
HLLBMAHE_02507 3.31e-190 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
HLLBMAHE_02508 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
HLLBMAHE_02509 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
HLLBMAHE_02510 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
HLLBMAHE_02511 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
HLLBMAHE_02512 1.02e-296 ypiA - - S - - - COG0457 FOG TPR repeat
HLLBMAHE_02513 1.64e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HLLBMAHE_02514 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
HLLBMAHE_02515 1.24e-256 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HLLBMAHE_02516 3.66e-184 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HLLBMAHE_02517 1.04e-291 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HLLBMAHE_02518 1.57e-150 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
HLLBMAHE_02519 4.88e-144 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
HLLBMAHE_02520 2.03e-228 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HLLBMAHE_02521 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HLLBMAHE_02522 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HLLBMAHE_02523 3.31e-262 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HLLBMAHE_02524 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HLLBMAHE_02525 3.03e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
HLLBMAHE_02526 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HLLBMAHE_02527 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLLBMAHE_02528 1.34e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HLLBMAHE_02529 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HLLBMAHE_02530 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HLLBMAHE_02531 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
HLLBMAHE_02532 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HLLBMAHE_02533 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HLLBMAHE_02534 2.14e-176 yphF - - - - - - -
HLLBMAHE_02535 7.09e-27 yphE - - S - - - Protein of unknown function (DUF2768)
HLLBMAHE_02536 1.05e-229 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
HLLBMAHE_02537 5.89e-314 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
HLLBMAHE_02538 5.91e-38 ypzH - - - - - - -
HLLBMAHE_02539 6.18e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
HLLBMAHE_02540 1.11e-133 yphA - - - - - - -
HLLBMAHE_02541 4.62e-11 - - - S - - - YpzI-like protein
HLLBMAHE_02542 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HLLBMAHE_02543 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
HLLBMAHE_02544 7.9e-144 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
HLLBMAHE_02545 2.48e-32 - - - S - - - Family of unknown function (DUF5359)
HLLBMAHE_02546 2.46e-139 ypfA - - M - - - Flagellar protein YcgR
HLLBMAHE_02547 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
HLLBMAHE_02548 6.93e-208 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
HLLBMAHE_02549 4.33e-154 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
HLLBMAHE_02550 1e-221 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
HLLBMAHE_02551 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HLLBMAHE_02552 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HLLBMAHE_02553 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
HLLBMAHE_02554 1.42e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
HLLBMAHE_02555 1.22e-142 ypbE - - M - - - Lysin motif
HLLBMAHE_02556 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
HLLBMAHE_02557 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
HLLBMAHE_02558 3.67e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
HLLBMAHE_02559 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
HLLBMAHE_02560 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HLLBMAHE_02561 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLLBMAHE_02562 1.08e-170 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HLLBMAHE_02563 4.8e-237 rsiX - - - - - - -
HLLBMAHE_02564 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_02565 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_02566 6.88e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_02567 4.67e-279 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HLLBMAHE_02568 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
HLLBMAHE_02569 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HLLBMAHE_02570 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HLLBMAHE_02571 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
HLLBMAHE_02572 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
HLLBMAHE_02573 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLLBMAHE_02574 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
HLLBMAHE_02575 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HLLBMAHE_02576 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HLLBMAHE_02577 1.45e-119 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
HLLBMAHE_02578 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLBMAHE_02579 1.4e-105 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HLLBMAHE_02580 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HLLBMAHE_02581 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
HLLBMAHE_02582 4.17e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HLLBMAHE_02583 5.98e-72 ypuD - - - - - - -
HLLBMAHE_02584 1.18e-132 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
HLLBMAHE_02585 1.02e-42 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
HLLBMAHE_02587 1.5e-33 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLLBMAHE_02588 4.28e-42 - - - S - - - Pfam Transposase IS66
HLLBMAHE_02594 1.23e-105 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HLLBMAHE_02595 8.93e-192 ypuA - - S - - - Secreted protein
HLLBMAHE_02596 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HLLBMAHE_02597 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
HLLBMAHE_02598 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
HLLBMAHE_02599 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
HLLBMAHE_02600 2.45e-245 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
HLLBMAHE_02601 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
HLLBMAHE_02602 3.14e-89 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
HLLBMAHE_02603 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
HLLBMAHE_02604 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_02605 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HLLBMAHE_02606 3e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
HLLBMAHE_02607 9.65e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
HLLBMAHE_02608 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HLLBMAHE_02609 4.59e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
HLLBMAHE_02610 3.75e-212 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
HLLBMAHE_02611 5.51e-50 - - - S - - - Protein of unknown function (DUF4227)
HLLBMAHE_02612 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
HLLBMAHE_02613 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HLLBMAHE_02614 2.97e-41 yqkK - - - - - - -
HLLBMAHE_02615 1.61e-308 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HLLBMAHE_02616 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
HLLBMAHE_02617 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
HLLBMAHE_02618 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
HLLBMAHE_02619 3.18e-77 ansR - - K - - - Transcriptional regulator
HLLBMAHE_02620 1.19e-279 yqxK - - L - - - DNA helicase
HLLBMAHE_02621 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
HLLBMAHE_02622 8.21e-10 - - - S - - - Protein of unknown function (DUF3936)
HLLBMAHE_02623 1.04e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
HLLBMAHE_02624 6.61e-26 yqkE - - S - - - Protein of unknown function (DUF3886)
HLLBMAHE_02625 9.3e-220 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
HLLBMAHE_02626 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
HLLBMAHE_02627 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
HLLBMAHE_02628 6.52e-248 yqkA - - K - - - GrpB protein
HLLBMAHE_02629 6.7e-73 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
HLLBMAHE_02630 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
HLLBMAHE_02631 3.23e-66 yqiX - - S - - - YolD-like protein
HLLBMAHE_02632 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLBMAHE_02634 2.01e-285 yqjV - - G - - - Major Facilitator Superfamily
HLLBMAHE_02636 7.72e-95 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_02637 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
HLLBMAHE_02638 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
HLLBMAHE_02639 1.39e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_02640 3.14e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HLLBMAHE_02641 3.25e-188 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLLBMAHE_02642 0.0 rocB - - E - - - arginine degradation protein
HLLBMAHE_02643 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HLLBMAHE_02644 6.4e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HLLBMAHE_02645 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HLLBMAHE_02646 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HLLBMAHE_02647 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HLLBMAHE_02648 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLLBMAHE_02649 1.84e-299 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HLLBMAHE_02650 1.77e-32 yqzJ - - - - - - -
HLLBMAHE_02651 7.27e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLLBMAHE_02652 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
HLLBMAHE_02653 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
HLLBMAHE_02654 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HLLBMAHE_02655 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
HLLBMAHE_02656 3.43e-128 yqjB - - S - - - protein conserved in bacteria
HLLBMAHE_02657 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
HLLBMAHE_02658 5.2e-166 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HLLBMAHE_02659 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HLLBMAHE_02660 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HLLBMAHE_02661 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
HLLBMAHE_02662 5.53e-210 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HLLBMAHE_02663 3.09e-267 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_02664 2.6e-194 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
HLLBMAHE_02665 7.61e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HLLBMAHE_02666 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HLLBMAHE_02667 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HLLBMAHE_02668 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HLLBMAHE_02669 4.82e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
HLLBMAHE_02670 2.24e-261 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HLLBMAHE_02671 3.02e-199 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
HLLBMAHE_02672 0.0 bkdR - - KT - - - Transcriptional regulator
HLLBMAHE_02673 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
HLLBMAHE_02674 1.46e-207 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HLLBMAHE_02675 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
HLLBMAHE_02676 1.85e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HLLBMAHE_02677 1.42e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
HLLBMAHE_02678 3.99e-198 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
HLLBMAHE_02679 1.1e-278 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
HLLBMAHE_02680 3.39e-168 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
HLLBMAHE_02681 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
HLLBMAHE_02682 2.26e-37 - - - - - - - -
HLLBMAHE_02683 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HLLBMAHE_02685 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HLLBMAHE_02686 1.26e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
HLLBMAHE_02687 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
HLLBMAHE_02688 1.53e-102 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
HLLBMAHE_02689 1.77e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
HLLBMAHE_02690 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HLLBMAHE_02691 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
HLLBMAHE_02692 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLLBMAHE_02693 3.55e-312 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HLLBMAHE_02694 1.07e-200 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HLLBMAHE_02695 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HLLBMAHE_02696 1.65e-88 yqhY - - S - - - protein conserved in bacteria
HLLBMAHE_02697 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HLLBMAHE_02698 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HLLBMAHE_02699 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
HLLBMAHE_02700 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
HLLBMAHE_02701 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
HLLBMAHE_02702 2.19e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
HLLBMAHE_02703 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
HLLBMAHE_02704 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
HLLBMAHE_02705 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
HLLBMAHE_02706 8.22e-217 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
HLLBMAHE_02707 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
HLLBMAHE_02708 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HLLBMAHE_02709 2.99e-249 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
HLLBMAHE_02710 9.59e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
HLLBMAHE_02711 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
HLLBMAHE_02712 2.98e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
HLLBMAHE_02713 5.18e-81 yqhP - - - - - - -
HLLBMAHE_02714 1.21e-210 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
HLLBMAHE_02715 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HLLBMAHE_02716 3.07e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HLLBMAHE_02717 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
HLLBMAHE_02718 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLLBMAHE_02719 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HLLBMAHE_02720 3.31e-262 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
HLLBMAHE_02721 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLLBMAHE_02722 1.77e-194 yqhG - - S - - - Bacterial protein YqhG of unknown function
HLLBMAHE_02723 1.39e-33 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
HLLBMAHE_02724 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
HLLBMAHE_02725 3.14e-182 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
HLLBMAHE_02726 7.4e-98 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
HLLBMAHE_02727 1.21e-150 yqxM - - - ko:K19433 - ko00000 -
HLLBMAHE_02728 1.24e-68 yqzG - - S - - - Protein of unknown function (DUF3889)
HLLBMAHE_02729 2.84e-36 yqzE - - S - - - YqzE-like protein
HLLBMAHE_02730 1.88e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
HLLBMAHE_02731 2.47e-61 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
HLLBMAHE_02732 1.77e-78 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
HLLBMAHE_02733 4e-85 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
HLLBMAHE_02734 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
HLLBMAHE_02735 2.5e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
HLLBMAHE_02736 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HLLBMAHE_02737 7.17e-232 yqxL - - P - - - Mg2 transporter protein
HLLBMAHE_02738 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HLLBMAHE_02739 8.33e-191 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HLLBMAHE_02741 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
HLLBMAHE_02742 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
HLLBMAHE_02743 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
HLLBMAHE_02744 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
HLLBMAHE_02745 7.34e-66 yqgV - - S - - - Thiamine-binding protein
HLLBMAHE_02746 9.37e-257 yqgU - - - - - - -
HLLBMAHE_02747 5.89e-281 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
HLLBMAHE_02748 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
HLLBMAHE_02749 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
HLLBMAHE_02750 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
HLLBMAHE_02751 1.58e-299 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
HLLBMAHE_02752 3.38e-14 yqgO - - - - - - -
HLLBMAHE_02753 3.25e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HLLBMAHE_02754 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
HLLBMAHE_02755 5.57e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
HLLBMAHE_02757 3.42e-68 yqzD - - - - - - -
HLLBMAHE_02758 1.09e-93 yqzC - - S - - - YceG-like family
HLLBMAHE_02759 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLLBMAHE_02760 9.78e-190 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HLLBMAHE_02761 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
HLLBMAHE_02762 2.89e-202 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
HLLBMAHE_02763 1.06e-204 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
HLLBMAHE_02764 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
HLLBMAHE_02765 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
HLLBMAHE_02766 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
HLLBMAHE_02767 8.25e-101 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
HLLBMAHE_02768 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
HLLBMAHE_02769 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
HLLBMAHE_02770 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HLLBMAHE_02771 2.04e-81 yqfX - - S - - - membrane
HLLBMAHE_02772 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
HLLBMAHE_02773 1.43e-105 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
HLLBMAHE_02774 3.83e-199 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HLLBMAHE_02775 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
HLLBMAHE_02776 2.1e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HLLBMAHE_02777 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HLLBMAHE_02778 1.17e-52 yqfQ - - S - - - YqfQ-like protein
HLLBMAHE_02779 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HLLBMAHE_02780 1.79e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HLLBMAHE_02781 6.9e-150 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
HLLBMAHE_02782 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HLLBMAHE_02783 2.79e-254 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HLLBMAHE_02784 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HLLBMAHE_02785 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
HLLBMAHE_02786 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HLLBMAHE_02787 3.29e-144 ccpN - - K - - - CBS domain
HLLBMAHE_02788 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
HLLBMAHE_02789 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
HLLBMAHE_02790 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
HLLBMAHE_02791 5.29e-27 - - - S - - - YqzL-like protein
HLLBMAHE_02792 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HLLBMAHE_02793 6.71e-93 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HLLBMAHE_02794 4.75e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
HLLBMAHE_02795 8.68e-106 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HLLBMAHE_02796 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
HLLBMAHE_02798 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
HLLBMAHE_02799 1.04e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
HLLBMAHE_02800 2.07e-60 yqfC - - S - - - sporulation protein YqfC
HLLBMAHE_02801 5.2e-78 yqfB - - - - - - -
HLLBMAHE_02802 4.35e-192 yqfA - - S - - - UPF0365 protein
HLLBMAHE_02803 3.1e-289 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
HLLBMAHE_02804 2.25e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
HLLBMAHE_02805 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
HLLBMAHE_02806 3.26e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
HLLBMAHE_02807 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
HLLBMAHE_02808 2.79e-178 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HLLBMAHE_02809 2.2e-223 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
HLLBMAHE_02810 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HLLBMAHE_02811 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
HLLBMAHE_02812 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HLLBMAHE_02813 2.44e-241 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HLLBMAHE_02814 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
HLLBMAHE_02815 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HLLBMAHE_02816 1.17e-68 yqxA - - S - - - Protein of unknown function (DUF3679)
HLLBMAHE_02817 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
HLLBMAHE_02818 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HLLBMAHE_02819 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
HLLBMAHE_02820 3.19e-241 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
HLLBMAHE_02821 2.36e-22 - - - S - - - YqzM-like protein
HLLBMAHE_02822 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
HLLBMAHE_02823 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
HLLBMAHE_02824 1.5e-134 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
HLLBMAHE_02825 3.66e-187 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HLLBMAHE_02826 5.67e-178 yqeM - - Q - - - Methyltransferase
HLLBMAHE_02827 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HLLBMAHE_02828 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
HLLBMAHE_02829 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HLLBMAHE_02830 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
HLLBMAHE_02831 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HLLBMAHE_02832 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HLLBMAHE_02833 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
HLLBMAHE_02835 9.11e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
HLLBMAHE_02836 1.68e-176 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
HLLBMAHE_02837 1.09e-133 yqeD - - S - - - SNARE associated Golgi protein
HLLBMAHE_02838 1.42e-212 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
HLLBMAHE_02839 6.34e-169 - - - - - - - -
HLLBMAHE_02840 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
HLLBMAHE_02841 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HLLBMAHE_02842 5.47e-44 - - - L ko:K06400 - ko00000 Recombinase
HLLBMAHE_02843 2.15e-90 psiE - - S ko:K13256 - ko00000 Protein PsiE homolog
HLLBMAHE_02844 3.48e-304 yrkQ - - T - - - Histidine kinase
HLLBMAHE_02845 7.15e-164 yrkP - - T ko:K02483 - ko00000,ko02022 Transcriptional regulator
HLLBMAHE_02846 3.57e-281 yrkO - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
HLLBMAHE_02847 5.41e-134 yrkN - - K - - - Acetyltransferase (GNAT) family
HLLBMAHE_02848 5.71e-126 yrkL - - S ko:K11748 - ko00000,ko02000 Flavodoxin-like fold
HLLBMAHE_02849 3.13e-104 - - - S - - - Protein of unknown function with HXXEE motif
HLLBMAHE_02850 6.77e-155 yrkJ - - S ko:K07090 - ko00000 membrane transporter protein
HLLBMAHE_02851 1.11e-49 yrkI - - O - - - Belongs to the sulfur carrier protein TusA family
HLLBMAHE_02852 6.2e-265 yrkH - - P - - - Rhodanese Homology Domain
HLLBMAHE_02853 2.04e-129 yrkF - - OP - - - Belongs to the sulfur carrier protein TusA family
HLLBMAHE_02854 1.61e-107 yrkE - - O - - - DsrE/DsrF/DrsH-like family
HLLBMAHE_02855 4.38e-52 yrkD - - S - - - protein conserved in bacteria
HLLBMAHE_02856 5.78e-29 - - - - - - - -
HLLBMAHE_02857 2.12e-136 yrkC - - G - - - Cupin domain
HLLBMAHE_02858 3.56e-194 bltR - - K - - - helix_turn_helix, mercury resistance
HLLBMAHE_02859 1.26e-267 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_02860 2.16e-108 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
HLLBMAHE_02861 4.16e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HLLBMAHE_02862 7.04e-23 - - - S - - - YrzO-like protein
HLLBMAHE_02863 5.56e-74 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HLLBMAHE_02864 4.58e-65 yraO - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HLLBMAHE_02865 7e-209 yraN - - K - - - Transcriptional regulator
HLLBMAHE_02866 1.15e-260 yraM - - S - - - PrpF protein
HLLBMAHE_02867 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HLLBMAHE_02868 5.07e-56 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_02869 1.39e-190 - - - S - - - Alpha beta hydrolase
HLLBMAHE_02870 6.61e-80 - - - T - - - sh3 domain protein
HLLBMAHE_02871 2.92e-81 - - - T - - - sh3 domain protein
HLLBMAHE_02872 6.62e-87 - - - E - - - Glyoxalase-like domain
HLLBMAHE_02873 4.19e-50 yraG - - - ko:K06440 - ko00000 -
HLLBMAHE_02874 9.61e-84 yraF - - M - - - Spore coat protein
HLLBMAHE_02875 3.41e-279 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLLBMAHE_02876 1.23e-35 yraE - - - ko:K06440 - ko00000 -
HLLBMAHE_02877 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
HLLBMAHE_02878 3.17e-68 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
HLLBMAHE_02879 4.53e-33 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
HLLBMAHE_02880 2.78e-252 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
HLLBMAHE_02881 1.85e-115 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
HLLBMAHE_02882 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HLLBMAHE_02883 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HLLBMAHE_02884 6.11e-168 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HLLBMAHE_02885 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
HLLBMAHE_02886 2.18e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
HLLBMAHE_02887 0.0 levR - - K - - - PTS system fructose IIA component
HLLBMAHE_02888 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_02889 5.63e-137 yrhP - - E - - - LysE type translocator
HLLBMAHE_02890 2.81e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
HLLBMAHE_02891 9.97e-114 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_02892 1.43e-190 rsiV - - S - - - Protein of unknown function (DUF3298)
HLLBMAHE_02893 0.0 oatA - - I - - - Acyltransferase family
HLLBMAHE_02894 6.32e-59 yrhK - - S - - - YrhK-like protein
HLLBMAHE_02895 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
HLLBMAHE_02896 3.76e-134 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
HLLBMAHE_02897 1.18e-121 yrhH - - Q - - - methyltransferase
HLLBMAHE_02898 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
HLLBMAHE_02900 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
HLLBMAHE_02901 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
HLLBMAHE_02902 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
HLLBMAHE_02903 6.05e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
HLLBMAHE_02904 6.93e-49 yrhC - - S - - - YrhC-like protein
HLLBMAHE_02905 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
HLLBMAHE_02906 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
HLLBMAHE_02907 5.64e-161 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HLLBMAHE_02908 5.71e-152 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
HLLBMAHE_02909 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
HLLBMAHE_02910 1.16e-101 yrrS - - S - - - Protein of unknown function (DUF1510)
HLLBMAHE_02911 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
HLLBMAHE_02912 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HLLBMAHE_02913 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
HLLBMAHE_02914 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
HLLBMAHE_02915 6.3e-222 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
HLLBMAHE_02916 2.32e-153 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
HLLBMAHE_02917 1.77e-240 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HLLBMAHE_02918 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
HLLBMAHE_02919 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HLLBMAHE_02920 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
HLLBMAHE_02921 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HLLBMAHE_02922 1.25e-241 yrrI - - S - - - AI-2E family transporter
HLLBMAHE_02923 5.42e-169 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
HLLBMAHE_02924 1.01e-184 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HLLBMAHE_02925 3.24e-139 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLLBMAHE_02926 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLLBMAHE_02927 5.38e-12 - - - S - - - Protein of unknown function (DUF3918)
HLLBMAHE_02928 8.4e-42 yrzR - - - - - - -
HLLBMAHE_02929 2.39e-106 yrrD - - S - - - protein conserved in bacteria
HLLBMAHE_02930 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HLLBMAHE_02931 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
HLLBMAHE_02932 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HLLBMAHE_02933 1.04e-269 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HLLBMAHE_02934 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_02935 6.98e-303 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HLLBMAHE_02936 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_02937 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HLLBMAHE_02938 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HLLBMAHE_02939 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
HLLBMAHE_02941 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
HLLBMAHE_02942 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HLLBMAHE_02943 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HLLBMAHE_02944 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HLLBMAHE_02945 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
HLLBMAHE_02946 5.09e-63 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
HLLBMAHE_02947 1.08e-112 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
HLLBMAHE_02948 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HLLBMAHE_02949 5.53e-65 yrzD - - S - - - Post-transcriptional regulator
HLLBMAHE_02950 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLLBMAHE_02951 8.28e-143 yrbG - - S - - - membrane
HLLBMAHE_02952 1.46e-96 yrzE - - S - - - Protein of unknown function (DUF3792)
HLLBMAHE_02953 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
HLLBMAHE_02954 1.12e-290 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HLLBMAHE_02955 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HLLBMAHE_02956 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
HLLBMAHE_02957 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HLLBMAHE_02958 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HLLBMAHE_02959 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
HLLBMAHE_02960 0.0 csbX - - EGP - - - the major facilitator superfamily
HLLBMAHE_02961 9.25e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
HLLBMAHE_02962 1.91e-151 yrzF - - T - - - serine threonine protein kinase
HLLBMAHE_02964 6.26e-68 - - - S - - - Family of unknown function (DUF5412)
HLLBMAHE_02965 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
HLLBMAHE_02966 2.47e-164 yebC - - K - - - transcriptional regulatory protein
HLLBMAHE_02967 2.55e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLLBMAHE_02968 9.89e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
HLLBMAHE_02969 1.08e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HLLBMAHE_02970 2.41e-200 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
HLLBMAHE_02971 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
HLLBMAHE_02972 4.76e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HLLBMAHE_02973 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
HLLBMAHE_02974 4.99e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
HLLBMAHE_02975 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
HLLBMAHE_02976 5.59e-308 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HLLBMAHE_02977 1.22e-138 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
HLLBMAHE_02978 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
HLLBMAHE_02979 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
HLLBMAHE_02980 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
HLLBMAHE_02981 3.74e-208 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
HLLBMAHE_02982 1.23e-185 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HLLBMAHE_02983 2.91e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
HLLBMAHE_02984 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HLLBMAHE_02985 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
HLLBMAHE_02986 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
HLLBMAHE_02987 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
HLLBMAHE_02988 1.39e-161 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
HLLBMAHE_02989 1.73e-132 maf - - D ko:K06287 - ko00000 septum formation protein Maf
HLLBMAHE_02990 1.74e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
HLLBMAHE_02991 1.05e-107 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HLLBMAHE_02992 2.22e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
HLLBMAHE_02993 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HLLBMAHE_02994 1.53e-35 - - - - - - - -
HLLBMAHE_02995 1.61e-250 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HLLBMAHE_02996 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
HLLBMAHE_02997 3.53e-312 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
HLLBMAHE_02998 3.7e-233 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
HLLBMAHE_02999 1.01e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
HLLBMAHE_03000 8.91e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HLLBMAHE_03001 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
HLLBMAHE_03002 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HLLBMAHE_03003 4.77e-116 ysxD - - - - - - -
HLLBMAHE_03004 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
HLLBMAHE_03005 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HLLBMAHE_03006 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
HLLBMAHE_03007 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HLLBMAHE_03008 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HLLBMAHE_03009 3.19e-239 ysoA - - H - - - Tetratricopeptide repeat
HLLBMAHE_03010 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLLBMAHE_03011 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HLLBMAHE_03012 1.75e-254 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HLLBMAHE_03013 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HLLBMAHE_03014 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HLLBMAHE_03015 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HLLBMAHE_03016 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
HLLBMAHE_03018 4.36e-103 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
HLLBMAHE_03019 1.11e-203 - - - N - - - domain, Protein
HLLBMAHE_03020 4.78e-183 ysnF - - S - - - protein conserved in bacteria
HLLBMAHE_03022 1.65e-118 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
HLLBMAHE_03023 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HLLBMAHE_03024 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HLLBMAHE_03025 5.65e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
HLLBMAHE_03026 4.49e-194 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
HLLBMAHE_03027 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLLBMAHE_03028 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_03029 2.65e-102 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
HLLBMAHE_03030 2.33e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HLLBMAHE_03031 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
HLLBMAHE_03032 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
HLLBMAHE_03033 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
HLLBMAHE_03034 3.96e-275 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
HLLBMAHE_03035 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HLLBMAHE_03036 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
HLLBMAHE_03037 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
HLLBMAHE_03039 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
HLLBMAHE_03040 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
HLLBMAHE_03041 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
HLLBMAHE_03042 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_03043 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HLLBMAHE_03044 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
HLLBMAHE_03045 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HLLBMAHE_03046 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
HLLBMAHE_03047 3.12e-111 yshB - - S - - - membrane protein, required for colicin V production
HLLBMAHE_03048 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HLLBMAHE_03049 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HLLBMAHE_03050 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLLBMAHE_03051 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HLLBMAHE_03052 3.13e-171 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HLLBMAHE_03053 4.37e-43 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
HLLBMAHE_03054 2.93e-259 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
HLLBMAHE_03055 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
HLLBMAHE_03056 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
HLLBMAHE_03057 8.42e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
HLLBMAHE_03058 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
HLLBMAHE_03059 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
HLLBMAHE_03060 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
HLLBMAHE_03061 7.9e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HLLBMAHE_03062 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
HLLBMAHE_03063 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HLLBMAHE_03064 2.52e-61 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HLLBMAHE_03065 1.46e-87 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
HLLBMAHE_03066 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HLLBMAHE_03067 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
HLLBMAHE_03068 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
HLLBMAHE_03069 4.56e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HLLBMAHE_03070 3.57e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
HLLBMAHE_03071 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
HLLBMAHE_03072 3.65e-59 ysdA - - S - - - Membrane
HLLBMAHE_03073 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HLLBMAHE_03074 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
HLLBMAHE_03075 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HLLBMAHE_03077 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLLBMAHE_03078 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HLLBMAHE_03079 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
HLLBMAHE_03080 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03081 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
HLLBMAHE_03082 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLLBMAHE_03084 2e-204 ytxC - - S - - - YtxC-like family
HLLBMAHE_03085 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
HLLBMAHE_03086 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
HLLBMAHE_03087 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
HLLBMAHE_03088 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HLLBMAHE_03089 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HLLBMAHE_03090 9.99e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLLBMAHE_03091 9.47e-86 ytcD - - K - - - Transcriptional regulator
HLLBMAHE_03092 1.6e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
HLLBMAHE_03093 4.54e-205 ytbE - - S - - - reductase
HLLBMAHE_03094 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HLLBMAHE_03095 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
HLLBMAHE_03096 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HLLBMAHE_03097 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HLLBMAHE_03098 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
HLLBMAHE_03099 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_03100 6.01e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
HLLBMAHE_03101 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
HLLBMAHE_03102 3.2e-265 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
HLLBMAHE_03103 9.38e-95 ytwI - - S - - - membrane
HLLBMAHE_03104 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
HLLBMAHE_03105 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
HLLBMAHE_03106 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
HLLBMAHE_03107 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HLLBMAHE_03108 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HLLBMAHE_03109 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HLLBMAHE_03110 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HLLBMAHE_03111 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
HLLBMAHE_03112 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
HLLBMAHE_03113 5.12e-112 ytrI - - - - - - -
HLLBMAHE_03114 1.15e-39 - - - - - - - -
HLLBMAHE_03115 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
HLLBMAHE_03116 2.15e-63 ytpI - - S - - - YtpI-like protein
HLLBMAHE_03117 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
HLLBMAHE_03118 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
HLLBMAHE_03119 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_03121 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
HLLBMAHE_03122 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
HLLBMAHE_03123 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
HLLBMAHE_03124 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HLLBMAHE_03125 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
HLLBMAHE_03126 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HLLBMAHE_03127 5.02e-90 ytfJ - - S - - - Sporulation protein YtfJ
HLLBMAHE_03128 6.29e-144 ytfI - - S - - - Protein of unknown function (DUF2953)
HLLBMAHE_03129 8.23e-112 yteJ - - S - - - RDD family
HLLBMAHE_03130 3.25e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
HLLBMAHE_03131 8.04e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HLLBMAHE_03133 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03134 0.0 ytcJ - - S - - - amidohydrolase
HLLBMAHE_03135 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLLBMAHE_03136 5.88e-38 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
HLLBMAHE_03137 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HLLBMAHE_03138 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
HLLBMAHE_03139 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
HLLBMAHE_03140 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HLLBMAHE_03141 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HLLBMAHE_03142 9.83e-141 yttP - - K - - - Transcriptional regulator
HLLBMAHE_03143 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_03144 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
HLLBMAHE_03145 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
HLLBMAHE_03146 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HLLBMAHE_03148 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLLBMAHE_03149 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HLLBMAHE_03150 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HLLBMAHE_03151 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
HLLBMAHE_03152 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
HLLBMAHE_03153 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
HLLBMAHE_03154 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
HLLBMAHE_03155 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
HLLBMAHE_03156 3.11e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HLLBMAHE_03157 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
HLLBMAHE_03158 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
HLLBMAHE_03159 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HLLBMAHE_03160 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03162 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
HLLBMAHE_03163 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
HLLBMAHE_03164 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HLLBMAHE_03165 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
HLLBMAHE_03166 3.17e-75 ytpP - - CO - - - Thioredoxin
HLLBMAHE_03167 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HLLBMAHE_03168 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
HLLBMAHE_03169 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
HLLBMAHE_03170 1.17e-67 ytzB - - S - - - small secreted protein
HLLBMAHE_03171 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
HLLBMAHE_03172 3.05e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
HLLBMAHE_03173 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HLLBMAHE_03174 9.51e-61 ytzH - - S - - - YtzH-like protein
HLLBMAHE_03175 3.02e-192 ytmP - - M - - - Phosphotransferase
HLLBMAHE_03176 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
HLLBMAHE_03177 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
HLLBMAHE_03178 9.92e-212 ytlQ - - - - - - -
HLLBMAHE_03179 1.5e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HLLBMAHE_03180 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
HLLBMAHE_03181 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
HLLBMAHE_03182 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
HLLBMAHE_03183 1.12e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
HLLBMAHE_03184 8.04e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLLBMAHE_03185 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
HLLBMAHE_03186 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
HLLBMAHE_03187 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLLBMAHE_03188 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
HLLBMAHE_03189 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
HLLBMAHE_03190 2.14e-36 yteV - - S - - - Sporulation protein Cse60
HLLBMAHE_03192 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
HLLBMAHE_03193 9.64e-94 yteS - - G - - - transport
HLLBMAHE_03194 8.3e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HLLBMAHE_03195 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
HLLBMAHE_03196 1.36e-202 ytdP - - K - - - Transcriptional regulator
HLLBMAHE_03197 2.13e-75 ytdP - - K - - - Transcriptional regulator
HLLBMAHE_03198 1.13e-165 ytdP - - K - - - Transcriptional regulator
HLLBMAHE_03199 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HLLBMAHE_03200 1.19e-190 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HLLBMAHE_03201 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
HLLBMAHE_03202 2e-174 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
HLLBMAHE_03203 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HLLBMAHE_03204 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HLLBMAHE_03205 4.1e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLLBMAHE_03206 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HLLBMAHE_03207 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HLLBMAHE_03208 4.8e-221 - - - S - - - Acetyl xylan esterase (AXE1)
HLLBMAHE_03209 4.37e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_03210 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
HLLBMAHE_03211 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLLBMAHE_03212 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HLLBMAHE_03213 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
HLLBMAHE_03214 1.22e-68 ytwF - - P - - - Sulfurtransferase
HLLBMAHE_03215 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
HLLBMAHE_03216 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
HLLBMAHE_03217 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HLLBMAHE_03218 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
HLLBMAHE_03219 5.71e-41 yttA - - S - - - Pfam Transposase IS66
HLLBMAHE_03220 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
HLLBMAHE_03221 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03222 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
HLLBMAHE_03223 2.23e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_03224 3.99e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HLLBMAHE_03225 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03226 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
HLLBMAHE_03227 4.46e-211 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_03228 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03229 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
HLLBMAHE_03231 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
HLLBMAHE_03232 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
HLLBMAHE_03233 2.75e-136 ytqB - - J - - - Putative rRNA methylase
HLLBMAHE_03234 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
HLLBMAHE_03235 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
HLLBMAHE_03236 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HLLBMAHE_03237 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_03238 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
HLLBMAHE_03239 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HLLBMAHE_03240 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HLLBMAHE_03241 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
HLLBMAHE_03242 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HLLBMAHE_03243 7.95e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HLLBMAHE_03244 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLLBMAHE_03245 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HLLBMAHE_03246 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
HLLBMAHE_03247 1.52e-79 ytkC - - S - - - Bacteriophage holin family
HLLBMAHE_03248 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
HLLBMAHE_03250 4.78e-95 ytkA - - S - - - YtkA-like
HLLBMAHE_03251 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HLLBMAHE_03252 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HLLBMAHE_03253 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
HLLBMAHE_03254 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HLLBMAHE_03255 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HLLBMAHE_03256 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
HLLBMAHE_03257 7.92e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HLLBMAHE_03258 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HLLBMAHE_03259 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HLLBMAHE_03260 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
HLLBMAHE_03261 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HLLBMAHE_03262 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HLLBMAHE_03263 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HLLBMAHE_03264 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HLLBMAHE_03265 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HLLBMAHE_03266 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HLLBMAHE_03267 1.44e-167 yteA - - T - - - COG1734 DnaK suppressor protein
HLLBMAHE_03268 5.69e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
HLLBMAHE_03269 4.1e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLLBMAHE_03270 2.78e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
HLLBMAHE_03271 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
HLLBMAHE_03273 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
HLLBMAHE_03274 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
HLLBMAHE_03275 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
HLLBMAHE_03276 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
HLLBMAHE_03277 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HLLBMAHE_03278 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
HLLBMAHE_03279 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
HLLBMAHE_03280 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HLLBMAHE_03281 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HLLBMAHE_03303 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
HLLBMAHE_03304 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
HLLBMAHE_03305 5.71e-121 - - - M - - - FR47-like protein
HLLBMAHE_03306 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
HLLBMAHE_03307 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
HLLBMAHE_03308 6.53e-108 yuaE - - S - - - DinB superfamily
HLLBMAHE_03309 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03310 1.12e-134 yuaD - - - - - - -
HLLBMAHE_03311 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
HLLBMAHE_03312 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HLLBMAHE_03313 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
HLLBMAHE_03314 5.83e-118 yuaB - - - - - - -
HLLBMAHE_03315 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
HLLBMAHE_03316 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
HLLBMAHE_03317 3.31e-52 yubF - - S - - - yiaA/B two helix domain
HLLBMAHE_03318 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLLBMAHE_03319 0.0 yubD - - P - - - Major Facilitator Superfamily
HLLBMAHE_03320 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
HLLBMAHE_03322 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HLLBMAHE_03323 1.73e-252 yubA - - S - - - transporter activity
HLLBMAHE_03324 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HLLBMAHE_03325 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
HLLBMAHE_03326 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
HLLBMAHE_03327 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HLLBMAHE_03328 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HLLBMAHE_03329 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
HLLBMAHE_03330 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_03331 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_03332 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_03333 2.02e-284 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_03334 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_03335 3.56e-180 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HLLBMAHE_03336 5e-48 - - - - - - - -
HLLBMAHE_03337 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HLLBMAHE_03338 7.23e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
HLLBMAHE_03339 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
HLLBMAHE_03340 2.16e-48 - - - - - - - -
HLLBMAHE_03341 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
HLLBMAHE_03342 1.69e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
HLLBMAHE_03343 2.75e-91 yugN - - S - - - YugN-like family
HLLBMAHE_03345 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
HLLBMAHE_03346 1.2e-285 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
HLLBMAHE_03347 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
HLLBMAHE_03348 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
HLLBMAHE_03349 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
HLLBMAHE_03350 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
HLLBMAHE_03351 6.74e-112 alaR - - K - - - Transcriptional regulator
HLLBMAHE_03352 9.89e-201 yugF - - I - - - Hydrolase
HLLBMAHE_03353 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
HLLBMAHE_03354 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HLLBMAHE_03355 1.39e-207 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03356 9.88e-63 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03357 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
HLLBMAHE_03358 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
HLLBMAHE_03360 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
HLLBMAHE_03361 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
HLLBMAHE_03362 1.92e-97 yuxK - - S - - - protein conserved in bacteria
HLLBMAHE_03363 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
HLLBMAHE_03364 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
HLLBMAHE_03365 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
HLLBMAHE_03366 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_03367 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
HLLBMAHE_03368 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03369 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HLLBMAHE_03370 1.15e-213 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HLLBMAHE_03371 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
HLLBMAHE_03372 1.42e-21 - - - - - - - -
HLLBMAHE_03373 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HLLBMAHE_03374 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLLBMAHE_03375 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLLBMAHE_03376 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLLBMAHE_03377 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLLBMAHE_03378 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HLLBMAHE_03379 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
HLLBMAHE_03380 9.49e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
HLLBMAHE_03381 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_03382 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03384 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
HLLBMAHE_03385 6.29e-10 - - - S - - - DegQ (SacQ) family
HLLBMAHE_03387 8.73e-09 yuzC - - - - - - -
HLLBMAHE_03388 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
HLLBMAHE_03389 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HLLBMAHE_03390 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
HLLBMAHE_03391 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
HLLBMAHE_03392 1.63e-52 yueH - - S - - - YueH-like protein
HLLBMAHE_03393 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
HLLBMAHE_03394 1.35e-244 yueF - - S - - - transporter activity
HLLBMAHE_03395 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
HLLBMAHE_03396 4e-31 - - - S - - - Protein of unknown function (DUF2642)
HLLBMAHE_03397 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
HLLBMAHE_03398 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_03399 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
HLLBMAHE_03400 0.0 yueB - - S - - - type VII secretion protein EsaA
HLLBMAHE_03401 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HLLBMAHE_03402 3.89e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
HLLBMAHE_03403 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
HLLBMAHE_03404 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
HLLBMAHE_03405 2.96e-292 yukF - - QT - - - Transcriptional regulator
HLLBMAHE_03406 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
HLLBMAHE_03407 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
HLLBMAHE_03408 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
HLLBMAHE_03409 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_03410 2.59e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
HLLBMAHE_03411 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
HLLBMAHE_03412 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
HLLBMAHE_03413 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_03414 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
HLLBMAHE_03415 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
HLLBMAHE_03416 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
HLLBMAHE_03417 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
HLLBMAHE_03418 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HLLBMAHE_03419 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
HLLBMAHE_03420 5.21e-148 yuiC - - S - - - protein conserved in bacteria
HLLBMAHE_03421 1.97e-46 yuiB - - S - - - Putative membrane protein
HLLBMAHE_03422 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HLLBMAHE_03423 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
HLLBMAHE_03425 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HLLBMAHE_03426 1.36e-123 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
HLLBMAHE_03427 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
HLLBMAHE_03428 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HLLBMAHE_03429 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLLBMAHE_03430 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
HLLBMAHE_03431 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
HLLBMAHE_03432 5.44e-74 yuzD - - S - - - protein conserved in bacteria
HLLBMAHE_03433 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
HLLBMAHE_03434 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
HLLBMAHE_03435 2.99e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HLLBMAHE_03436 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HLLBMAHE_03437 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
HLLBMAHE_03438 2.57e-252 yutH - - S - - - Spore coat protein
HLLBMAHE_03439 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
HLLBMAHE_03440 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HLLBMAHE_03441 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
HLLBMAHE_03442 3.2e-63 yutD - - S - - - protein conserved in bacteria
HLLBMAHE_03443 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HLLBMAHE_03444 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HLLBMAHE_03445 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
HLLBMAHE_03446 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
HLLBMAHE_03447 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
HLLBMAHE_03448 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
HLLBMAHE_03449 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
HLLBMAHE_03450 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
HLLBMAHE_03451 1.07e-79 yunG - - - - - - -
HLLBMAHE_03452 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HLLBMAHE_03453 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
HLLBMAHE_03454 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
HLLBMAHE_03455 4.37e-273 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
HLLBMAHE_03456 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HLLBMAHE_03457 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HLLBMAHE_03459 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
HLLBMAHE_03460 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HLLBMAHE_03461 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HLLBMAHE_03462 2.47e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HLLBMAHE_03463 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
HLLBMAHE_03464 7.18e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HLLBMAHE_03465 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HLLBMAHE_03466 4.82e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HLLBMAHE_03467 4.42e-216 bsn - - L - - - Ribonuclease
HLLBMAHE_03468 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_03469 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
HLLBMAHE_03470 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
HLLBMAHE_03471 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HLLBMAHE_03472 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
HLLBMAHE_03473 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
HLLBMAHE_03474 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
HLLBMAHE_03475 9.11e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HLLBMAHE_03476 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
HLLBMAHE_03477 2.63e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
HLLBMAHE_03479 3.35e-56 - - - - - - - -
HLLBMAHE_03480 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
HLLBMAHE_03481 4.63e-72 - - - L - - - transposase activity
HLLBMAHE_03482 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_03483 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
HLLBMAHE_03484 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
HLLBMAHE_03485 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
HLLBMAHE_03486 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HLLBMAHE_03487 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
HLLBMAHE_03488 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HLLBMAHE_03489 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HLLBMAHE_03490 1.96e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
HLLBMAHE_03491 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
HLLBMAHE_03492 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HLLBMAHE_03493 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
HLLBMAHE_03494 8.14e-73 yusE - - CO - - - Thioredoxin
HLLBMAHE_03495 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
HLLBMAHE_03496 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
HLLBMAHE_03497 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HLLBMAHE_03498 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
HLLBMAHE_03499 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
HLLBMAHE_03500 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
HLLBMAHE_03501 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
HLLBMAHE_03502 1.11e-13 - - - S - - - YuzL-like protein
HLLBMAHE_03503 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
HLLBMAHE_03504 2.23e-54 - - - - - - - -
HLLBMAHE_03505 8.66e-70 yusN - - M - - - Coat F domain
HLLBMAHE_03506 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
HLLBMAHE_03507 0.0 yusP - - P - - - Major facilitator superfamily
HLLBMAHE_03508 4.86e-84 yusQ - - S - - - Tautomerase enzyme
HLLBMAHE_03509 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_03510 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
HLLBMAHE_03511 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
HLLBMAHE_03512 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLLBMAHE_03513 3.48e-88 - - - S - - - YusW-like protein
HLLBMAHE_03514 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
HLLBMAHE_03516 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
HLLBMAHE_03517 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
HLLBMAHE_03518 6.4e-09 - - - J - - - O-methyltransferase
HLLBMAHE_03519 2.94e-17 - - - EGP - - - Major Facilitator
HLLBMAHE_03521 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
HLLBMAHE_03523 1.26e-18 - - - - - - - -
HLLBMAHE_03524 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HLLBMAHE_03525 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_03526 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
HLLBMAHE_03528 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03529 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLLBMAHE_03530 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_03531 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03532 3.06e-204 yuxN - - K - - - Transcriptional regulator
HLLBMAHE_03533 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HLLBMAHE_03534 2.6e-33 - - - S - - - Protein of unknown function (DUF3970)
HLLBMAHE_03535 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
HLLBMAHE_03536 1.13e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HLLBMAHE_03537 8.74e-243 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
HLLBMAHE_03538 1.1e-139 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_03539 2.35e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03540 7.65e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
HLLBMAHE_03541 6.68e-171 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
HLLBMAHE_03542 8.52e-144 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HLLBMAHE_03543 3.05e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
HLLBMAHE_03544 4.58e-288 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_03545 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
HLLBMAHE_03546 6.62e-312 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HLLBMAHE_03547 9.42e-237 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_03548 8.18e-216 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HLLBMAHE_03549 2.12e-181 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_03550 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
HLLBMAHE_03551 0.0 yvrG - - T - - - Histidine kinase
HLLBMAHE_03552 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_03553 6.16e-33 - - - - - - - -
HLLBMAHE_03554 5.77e-127 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
HLLBMAHE_03555 3.46e-26 - - - S - - - YvrJ protein family
HLLBMAHE_03556 1.53e-290 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
HLLBMAHE_03557 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
HLLBMAHE_03558 6.32e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
HLLBMAHE_03559 3.82e-158 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03560 2.42e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
HLLBMAHE_03561 9.78e-190 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLLBMAHE_03562 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_03563 1.16e-234 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HLLBMAHE_03564 2.57e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLLBMAHE_03566 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
HLLBMAHE_03567 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
HLLBMAHE_03568 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
HLLBMAHE_03569 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
HLLBMAHE_03570 2.97e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
HLLBMAHE_03571 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
HLLBMAHE_03572 6.08e-154 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
HLLBMAHE_03573 6.19e-201 yvgN - - S - - - reductase
HLLBMAHE_03574 9.32e-112 yvgO - - - - - - -
HLLBMAHE_03575 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
HLLBMAHE_03576 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HLLBMAHE_03577 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HLLBMAHE_03578 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
HLLBMAHE_03580 2.34e-139 yvgT - - S - - - membrane
HLLBMAHE_03581 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
HLLBMAHE_03582 3.45e-137 bdbD - - O - - - Thioredoxin
HLLBMAHE_03583 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
HLLBMAHE_03584 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
HLLBMAHE_03585 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
HLLBMAHE_03586 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
HLLBMAHE_03587 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
HLLBMAHE_03588 2.95e-153 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HLLBMAHE_03589 0.0 - - - S - - - Fusaric acid resistance protein-like
HLLBMAHE_03590 5.79e-97 yvaD - - S - - - Family of unknown function (DUF5360)
HLLBMAHE_03591 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
HLLBMAHE_03592 9.98e-128 - - - K - - - Bacterial regulatory proteins, tetR family
HLLBMAHE_03593 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_03597 4.33e-256 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
HLLBMAHE_03598 3.29e-53 - - - - - - - -
HLLBMAHE_03600 2.17e-154 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
HLLBMAHE_03601 7.62e-76 - - - S - - - Bacteriophage holin family
HLLBMAHE_03602 2.14e-07 - - - S - - - Phage uncharacterised protein (Phage_XkdX)
HLLBMAHE_03604 4.24e-65 - - - S - - - Domain of unknown function (DUF2479)
HLLBMAHE_03607 2.66e-61 - - - - - - - -
HLLBMAHE_03608 2.33e-309 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
HLLBMAHE_03609 3.58e-144 - - - S - - - Phage tail protein
HLLBMAHE_03610 0.0 - - - S - - - peptidoglycan catabolic process
HLLBMAHE_03611 1e-16 - - - - - - - -
HLLBMAHE_03612 1.11e-36 - - - - - - - -
HLLBMAHE_03613 9.58e-77 - - - - - - - -
HLLBMAHE_03614 3.8e-30 - - - - - - - -
HLLBMAHE_03615 1.6e-64 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
HLLBMAHE_03616 5.25e-34 - - - S - - - Phage gp6-like head-tail connector protein
HLLBMAHE_03617 4.31e-39 - - - S - - - peptidoglycan catabolic process
HLLBMAHE_03618 8.29e-09 - - - S - - - peptidoglycan catabolic process
HLLBMAHE_03619 1.61e-273 - - - S - - - peptidase activity
HLLBMAHE_03620 2.57e-132 - - - S - - - peptidase activity
HLLBMAHE_03621 4.09e-274 - - - S - - - Phage portal protein
HLLBMAHE_03622 5.41e-14 - - - - - - - -
HLLBMAHE_03623 2.05e-279 - - - S - - - Phage Terminase
HLLBMAHE_03624 4.07e-89 - - - S - - - Phage terminase, small subunit
HLLBMAHE_03625 1.08e-25 - - - - - - - -
HLLBMAHE_03626 1.07e-81 - - - S - - - HNH endonuclease
HLLBMAHE_03631 8.47e-78 - - - L - - - Phage integrase family
HLLBMAHE_03632 6.22e-67 - - - M - - - ArpU family transcriptional regulator
HLLBMAHE_03634 1.92e-44 - - - - - - - -
HLLBMAHE_03642 3.96e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
HLLBMAHE_03643 5.18e-118 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
HLLBMAHE_03646 6.87e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HLLBMAHE_03647 2.34e-57 - - - K - - - Helix-turn-helix XRE-family like proteins
HLLBMAHE_03650 1.67e-77 - - - - - - - -
HLLBMAHE_03651 3.67e-155 - - - S - - - Phage integrase family
HLLBMAHE_03653 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HLLBMAHE_03654 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HLLBMAHE_03655 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
HLLBMAHE_03656 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
HLLBMAHE_03657 1.58e-193 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
HLLBMAHE_03658 4.9e-48 yvzC - - K - - - transcriptional
HLLBMAHE_03659 4.08e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
HLLBMAHE_03660 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
HLLBMAHE_03661 3.85e-72 yvaP - - K - - - transcriptional
HLLBMAHE_03662 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
HLLBMAHE_03663 2.07e-194 spaK 2.7.13.3 - T ko:K20487 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 His Kinase A (phosphoacceptor) domain
HLLBMAHE_03664 1.41e-135 spaR - - K ko:K20488 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 Transcriptional regulatory protein, C terminal
HLLBMAHE_03665 2.99e-103 spaG - - S ko:K20492 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_03666 1.67e-110 spaE - - S ko:K20491 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_03667 7.1e-131 spaF - - V ko:K01990,ko:K20490 ko02010,ko02020,ko02024,map02010,map02020,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03670 1.87e-96 spaC1 - - V ko:K20484 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lanthionine synthetase C-like protein
HLLBMAHE_03671 8.57e-193 - - - V ko:K06147,ko:K06148,ko:K20485 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko02000 ABC transporter
HLLBMAHE_03672 1.64e-230 bsaB - - S ko:K20483 ko02020,ko02024,map02020,map02024 ko00000,ko00001 Lantibiotic dehydratase, C terminus
HLLBMAHE_03673 1.01e-133 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HLLBMAHE_03674 1.13e-218 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLLBMAHE_03675 1.55e-142 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HLLBMAHE_03676 4.07e-268 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLLBMAHE_03677 6.63e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HLLBMAHE_03678 5.59e-136 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HLLBMAHE_03679 3.01e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HLLBMAHE_03680 5.63e-145 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
HLLBMAHE_03681 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HLLBMAHE_03682 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
HLLBMAHE_03683 2.77e-135 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
HLLBMAHE_03684 2.96e-145 yvbH - - S - - - YvbH-like oligomerisation region
HLLBMAHE_03685 1.32e-155 yvbI - - M - - - Membrane
HLLBMAHE_03686 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
HLLBMAHE_03687 9.77e-106 yvbK - - K - - - acetyltransferase
HLLBMAHE_03688 3.81e-219 - - - EGP - - - Major facilitator Superfamily
HLLBMAHE_03689 1.25e-192 - - - - - - - -
HLLBMAHE_03690 5.37e-147 - - - S - - - GlcNAc-PI de-N-acetylase
HLLBMAHE_03691 3.37e-156 - - - C - - - WbqC-like protein family
HLLBMAHE_03692 2.55e-144 - - - M - - - Protein involved in cellulose biosynthesis
HLLBMAHE_03693 2.44e-198 - - - E - - - UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HLLBMAHE_03694 6.08e-188 arnA 4.2.1.46, 5.1.3.2 - M ko:K01710,ko:K01784 ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130 ko00000,ko00001,ko00002,ko01000 GDP-mannose 4,6 dehydratase
HLLBMAHE_03695 3.92e-236 - 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HLLBMAHE_03696 4.53e-274 - 1.1.1.136 - M ko:K13015 ko00520,map00520 ko00000,ko00001,ko01000,ko01005 UDP binding domain
HLLBMAHE_03697 1.22e-208 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HLLBMAHE_03698 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HLLBMAHE_03699 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
HLLBMAHE_03700 7.1e-175 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HLLBMAHE_03701 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
HLLBMAHE_03702 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HLLBMAHE_03703 2.42e-237 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLLBMAHE_03704 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_03705 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
HLLBMAHE_03706 1.04e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLLBMAHE_03707 4.9e-206 yvbU - - K - - - Transcriptional regulator
HLLBMAHE_03708 3.93e-198 yvbV - - EG - - - EamA-like transporter family
HLLBMAHE_03709 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
HLLBMAHE_03710 3.91e-245 - - - S - - - Glycosyl hydrolase
HLLBMAHE_03711 9.77e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLLBMAHE_03712 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HLLBMAHE_03713 9.08e-175 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HLLBMAHE_03714 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
HLLBMAHE_03715 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
HLLBMAHE_03716 7.23e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_03717 8.18e-247 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_03718 2.04e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
HLLBMAHE_03719 6.37e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
HLLBMAHE_03720 4.9e-199 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
HLLBMAHE_03721 5.07e-264 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
HLLBMAHE_03722 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
HLLBMAHE_03723 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
HLLBMAHE_03724 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HLLBMAHE_03725 2.15e-300 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HLLBMAHE_03726 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HLLBMAHE_03727 2.33e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_03728 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
HLLBMAHE_03729 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
HLLBMAHE_03730 4.25e-307 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HLLBMAHE_03731 5.69e-44 yvfG - - S - - - YvfG protein
HLLBMAHE_03732 1.03e-238 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
HLLBMAHE_03733 5.25e-279 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
HLLBMAHE_03734 1.15e-80 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HLLBMAHE_03735 3.72e-138 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLLBMAHE_03736 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLLBMAHE_03737 1.86e-243 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLBMAHE_03738 3.16e-258 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
HLLBMAHE_03739 1.22e-248 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HLLBMAHE_03740 1.03e-263 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
HLLBMAHE_03741 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
HLLBMAHE_03742 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
HLLBMAHE_03743 2.83e-284 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
HLLBMAHE_03744 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
HLLBMAHE_03745 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HLLBMAHE_03746 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
HLLBMAHE_03747 3.57e-98 - - - K ko:K19417 - ko00000,ko03000 transcriptional
HLLBMAHE_03748 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
HLLBMAHE_03750 8.97e-119 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
HLLBMAHE_03751 7.42e-95 - - - S - - - Protein of unknown function (DUF3237)
HLLBMAHE_03752 8.37e-161 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
HLLBMAHE_03753 0.0 pbpE - - V - - - Beta-lactamase
HLLBMAHE_03754 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
HLLBMAHE_03755 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
HLLBMAHE_03756 0.0 ybeC - - E - - - amino acid
HLLBMAHE_03757 2.75e-136 yvdT_1 - - K - - - Transcriptional regulator
HLLBMAHE_03758 1.05e-66 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
HLLBMAHE_03759 1.03e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
HLLBMAHE_03760 1.85e-120 yvdQ - - S - - - Protein of unknown function (DUF3231)
HLLBMAHE_03762 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HLLBMAHE_03763 7.59e-147 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
HLLBMAHE_03764 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
HLLBMAHE_03765 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
HLLBMAHE_03766 8.67e-197 malA - - S - - - Protein of unknown function (DUF1189)
HLLBMAHE_03767 2.79e-189 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
HLLBMAHE_03768 1.18e-308 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
HLLBMAHE_03769 4.89e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
HLLBMAHE_03770 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
HLLBMAHE_03771 1.54e-221 yvdE - - K - - - Transcriptional regulator
HLLBMAHE_03772 4.42e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
HLLBMAHE_03773 7.84e-71 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
HLLBMAHE_03774 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
HLLBMAHE_03775 8.79e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
HLLBMAHE_03776 3.84e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HLLBMAHE_03777 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
HLLBMAHE_03778 4.46e-181 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_03779 3.95e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
HLLBMAHE_03780 1.56e-170 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_03781 5.4e-43 - - - - - - - -
HLLBMAHE_03782 4.45e-180 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
HLLBMAHE_03783 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
HLLBMAHE_03784 4.24e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
HLLBMAHE_03785 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
HLLBMAHE_03786 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
HLLBMAHE_03787 2.39e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HLLBMAHE_03788 1.18e-225 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HLLBMAHE_03789 1.66e-181 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
HLLBMAHE_03790 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
HLLBMAHE_03791 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
HLLBMAHE_03792 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_03794 1.23e-312 - - - - - - - -
HLLBMAHE_03795 2.78e-103 - - - - - - - -
HLLBMAHE_03797 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03798 2.41e-142 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
HLLBMAHE_03799 3.8e-174 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HLLBMAHE_03800 5.38e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HLLBMAHE_03801 1.15e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HLLBMAHE_03802 1.36e-136 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
HLLBMAHE_03803 3e-291 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HLLBMAHE_03804 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HLLBMAHE_03805 9.84e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HLLBMAHE_03806 6.12e-179 yvpB - - NU - - - protein conserved in bacteria
HLLBMAHE_03807 1.05e-151 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
HLLBMAHE_03808 3.58e-119 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
HLLBMAHE_03809 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HLLBMAHE_03810 2.06e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
HLLBMAHE_03811 2.61e-194 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HLLBMAHE_03812 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HLLBMAHE_03813 5.67e-278 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
HLLBMAHE_03814 1.67e-163 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HLLBMAHE_03815 1.23e-170 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
HLLBMAHE_03816 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
HLLBMAHE_03817 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
HLLBMAHE_03818 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
HLLBMAHE_03819 9.16e-218 yvlB - - S - - - Putative adhesin
HLLBMAHE_03820 3.3e-64 yvlA - - - - - - -
HLLBMAHE_03821 2.25e-45 yvkN - - - - - - -
HLLBMAHE_03822 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLLBMAHE_03823 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HLLBMAHE_03824 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HLLBMAHE_03825 2.54e-42 csbA - - S - - - protein conserved in bacteria
HLLBMAHE_03826 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
HLLBMAHE_03827 1.43e-131 yvkB - - K - - - Transcriptional regulator
HLLBMAHE_03828 1.23e-294 yvkA - - P - - - -transporter
HLLBMAHE_03829 3.86e-281 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLLBMAHE_03830 7.98e-73 swrA - - S - - - Swarming motility protein
HLLBMAHE_03831 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
HLLBMAHE_03832 1.1e-198 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HLLBMAHE_03833 1.5e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
HLLBMAHE_03834 2.56e-72 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
HLLBMAHE_03835 1.86e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
HLLBMAHE_03836 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HLLBMAHE_03837 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HLLBMAHE_03838 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HLLBMAHE_03839 7.52e-87 - - - - - - - -
HLLBMAHE_03840 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
HLLBMAHE_03841 5.15e-91 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
HLLBMAHE_03842 1.34e-314 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HLLBMAHE_03843 1.1e-76 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
HLLBMAHE_03844 1.43e-124 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HLLBMAHE_03845 3.02e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HLLBMAHE_03846 2.48e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HLLBMAHE_03847 1.7e-92 yviE - - - - - - -
HLLBMAHE_03848 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
HLLBMAHE_03849 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
HLLBMAHE_03850 1e-101 yvyG - - NOU - - - FlgN protein
HLLBMAHE_03851 4.32e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
HLLBMAHE_03852 1.83e-96 yvyF - - S - - - flagellar protein
HLLBMAHE_03853 1.86e-161 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
HLLBMAHE_03854 1.04e-60 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
HLLBMAHE_03855 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HLLBMAHE_03856 3.56e-198 degV - - S - - - protein conserved in bacteria
HLLBMAHE_03857 7.16e-163 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HLLBMAHE_03858 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HLLBMAHE_03859 2.41e-155 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
HLLBMAHE_03860 9.37e-224 yvhJ - - K - - - Transcriptional regulator
HLLBMAHE_03861 2.1e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HLLBMAHE_03862 8e-295 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
HLLBMAHE_03863 8.42e-187 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
HLLBMAHE_03864 5.79e-147 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
HLLBMAHE_03865 0.0 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
HLLBMAHE_03866 0.0 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLLBMAHE_03867 2.41e-280 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
HLLBMAHE_03868 2.58e-316 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HLLBMAHE_03869 2.12e-143 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HLLBMAHE_03870 0.0 lytC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
HLLBMAHE_03871 1.94e-61 lytB - - D - - - Stage II sporulation protein
HLLBMAHE_03872 1.81e-47 - - - - - - - -
HLLBMAHE_03873 1.13e-218 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HLLBMAHE_03874 7.39e-275 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HLLBMAHE_03876 3.59e-143 - - - M - - - Glycosyl transferases group 1
HLLBMAHE_03877 2.74e-208 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
HLLBMAHE_03878 0.0 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HLLBMAHE_03879 2.48e-170 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
HLLBMAHE_03880 7.34e-69 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
HLLBMAHE_03881 3.39e-111 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HLLBMAHE_03882 1.91e-117 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HLLBMAHE_03883 1.03e-134 tarI 2.7.7.40, 2.7.7.60 - I ko:K00991,ko:K21030 ko00040,ko00900,ko01100,ko01110,ko01130,map00040,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HLLBMAHE_03884 5.68e-186 tarJ 1.1.1.137, 1.1.1.405 - E ko:K05352,ko:K21680 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HLLBMAHE_03885 4.73e-110 tarK 2.7.8.14, 2.7.8.46, 2.7.8.47 - M ko:K18704,ko:K21592 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLLBMAHE_03886 1.42e-235 tarL 2.7.8.14, 2.7.8.47 - M ko:K18704 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HLLBMAHE_03887 6.16e-67 - - - S - - - alpha beta
HLLBMAHE_03888 2.03e-149 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLLBMAHE_03889 8.04e-200 capO 1.1.1.336 - M ko:K02472 ko00520,ko05111,map00520,map05111 ko00000,ko00001,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLLBMAHE_03890 4.19e-148 - - - M - - - DUF based on E. rectale Gene description (DUF3880)
HLLBMAHE_03892 1.29e-198 - - - M - - - Glycosyl transferases group 1
HLLBMAHE_03893 3.18e-161 - - - M - - - Glycosyl transferase group 1 protein
HLLBMAHE_03894 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HLLBMAHE_03895 5.51e-240 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
HLLBMAHE_03896 1.55e-310 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
HLLBMAHE_03897 1.65e-245 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
HLLBMAHE_03898 2.07e-262 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
HLLBMAHE_03899 1.51e-313 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_03900 1.67e-176 ywtF_2 - - K - - - Transcriptional regulator
HLLBMAHE_03901 2.71e-200 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HLLBMAHE_03902 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03904 1.37e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HLLBMAHE_03905 2.29e-29 ywtC - - - - - - -
HLLBMAHE_03906 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HLLBMAHE_03907 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
HLLBMAHE_03908 2.08e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
HLLBMAHE_03909 9.35e-228 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
HLLBMAHE_03910 2.62e-206 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HLLBMAHE_03911 2.28e-84 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HLLBMAHE_03912 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HLLBMAHE_03913 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
HLLBMAHE_03914 3.68e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
HLLBMAHE_03915 3.97e-119 batE - - T - - - Sh3 type 3 domain protein
HLLBMAHE_03916 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
HLLBMAHE_03917 1.2e-123 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
HLLBMAHE_03918 1.84e-187 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
HLLBMAHE_03919 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
HLLBMAHE_03920 3.36e-218 alsR - - K - - - LysR substrate binding domain
HLLBMAHE_03921 9.31e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HLLBMAHE_03922 5.05e-161 ywrJ - - - - - - -
HLLBMAHE_03923 3.72e-174 cotB - - - ko:K06325 - ko00000 -
HLLBMAHE_03924 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
HLLBMAHE_03925 1e-17 - - - - - - - -
HLLBMAHE_03926 1.03e-141 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HLLBMAHE_03927 3.02e-69 - - - S - - - Domain of unknown function (DUF4181)
HLLBMAHE_03928 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
HLLBMAHE_03929 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
HLLBMAHE_03930 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
HLLBMAHE_03931 6.07e-114 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
HLLBMAHE_03933 4.65e-168 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HLLBMAHE_03934 1.36e-71 - - - S - - - MORN repeat variant
HLLBMAHE_03935 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
HLLBMAHE_03936 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
HLLBMAHE_03938 2.42e-195 ywqG - - S - - - Domain of unknown function (DUF1963)
HLLBMAHE_03939 9.4e-313 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HLLBMAHE_03940 1.44e-179 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
HLLBMAHE_03941 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
HLLBMAHE_03942 8.84e-162 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
HLLBMAHE_03943 3.6e-25 - - - - - - - -
HLLBMAHE_03944 0.0 ywqB - - S - - - SWIM zinc finger
HLLBMAHE_03945 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
HLLBMAHE_03946 3.42e-198 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
HLLBMAHE_03947 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HLLBMAHE_03948 6.34e-66 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
HLLBMAHE_03949 2.51e-18 - - - M - - - cell wall anchor domain
HLLBMAHE_03950 1.28e-66 ywpD - - T - - - Histidine kinase
HLLBMAHE_03952 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_03953 1.61e-77 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HLLBMAHE_03954 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HLLBMAHE_03955 5.45e-257 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
HLLBMAHE_03956 4.1e-182 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HLLBMAHE_03957 1.45e-171 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
HLLBMAHE_03958 2.91e-230 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
HLLBMAHE_03959 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
HLLBMAHE_03960 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
HLLBMAHE_03961 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_03962 1.14e-309 ywoF - - P - - - Right handed beta helix region
HLLBMAHE_03963 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
HLLBMAHE_03964 1.54e-306 ywoD - - EGP - - - Major facilitator superfamily
HLLBMAHE_03965 1.22e-132 yjgF - - Q - - - Isochorismatase family
HLLBMAHE_03966 5.89e-100 - - - - - - - -
HLLBMAHE_03967 6.5e-288 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
HLLBMAHE_03968 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
HLLBMAHE_03969 1.21e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
HLLBMAHE_03970 7.75e-94 ywnJ - - S - - - VanZ like family
HLLBMAHE_03971 2.63e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
HLLBMAHE_03972 3.65e-115 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
HLLBMAHE_03973 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
HLLBMAHE_03974 4.73e-234 - - - M - - - NeuB family
HLLBMAHE_03975 1.43e-91 ywnF - - S - - - Family of unknown function (DUF5392)
HLLBMAHE_03976 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLLBMAHE_03977 1.97e-183 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
HLLBMAHE_03978 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
HLLBMAHE_03979 1.69e-144 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
HLLBMAHE_03980 4.58e-85 ywnA - - K - - - Transcriptional regulator
HLLBMAHE_03981 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HLLBMAHE_03982 3.2e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
HLLBMAHE_03983 3.34e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
HLLBMAHE_03984 1.11e-21 csbD - - K - - - CsbD-like
HLLBMAHE_03985 1.21e-109 ywmF - - S - - - Peptidase M50
HLLBMAHE_03986 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_03987 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HLLBMAHE_03988 2.22e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HLLBMAHE_03990 5.87e-155 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HLLBMAHE_03991 7.71e-157 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
HLLBMAHE_03992 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
HLLBMAHE_03993 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLLBMAHE_03994 2.3e-172 ywmB - - S - - - TATA-box binding
HLLBMAHE_03995 4.54e-45 ywzB - - S - - - membrane
HLLBMAHE_03996 7.16e-114 ywmA - - - - - - -
HLLBMAHE_03997 3.89e-72 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
HLLBMAHE_03998 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HLLBMAHE_03999 1.82e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HLLBMAHE_04000 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HLLBMAHE_04001 7.94e-116 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLLBMAHE_04002 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HLLBMAHE_04003 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HLLBMAHE_04004 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
HLLBMAHE_04005 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
HLLBMAHE_04006 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HLLBMAHE_04007 1.25e-302 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HLLBMAHE_04008 1.44e-122 ywlG - - S - - - Belongs to the UPF0340 family
HLLBMAHE_04009 2.35e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
HLLBMAHE_04010 1.58e-100 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HLLBMAHE_04011 4.56e-117 mntP - - P - - - Probably functions as a manganese efflux pump
HLLBMAHE_04012 7.37e-251 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HLLBMAHE_04013 1.79e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
HLLBMAHE_04014 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
HLLBMAHE_04015 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
HLLBMAHE_04017 1.99e-203 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HLLBMAHE_04018 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HLLBMAHE_04019 3.99e-88 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_04020 2.85e-115 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HLLBMAHE_04021 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
HLLBMAHE_04022 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
HLLBMAHE_04023 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
HLLBMAHE_04024 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
HLLBMAHE_04025 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HLLBMAHE_04026 3.51e-225 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
HLLBMAHE_04027 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HLLBMAHE_04028 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HLLBMAHE_04029 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
HLLBMAHE_04030 3.08e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
HLLBMAHE_04031 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
HLLBMAHE_04032 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HLLBMAHE_04033 1.03e-82 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HLLBMAHE_04034 2.98e-269 acdA - - I - - - acyl-CoA dehydrogenase
HLLBMAHE_04035 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
HLLBMAHE_04036 4.55e-285 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HLLBMAHE_04037 1.63e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HLLBMAHE_04038 1.32e-57 ywjC - - - - - - -
HLLBMAHE_04039 1.51e-121 ywjB - - H - - - RibD C-terminal domain
HLLBMAHE_04040 0.0 ywjA - - V ko:K06147 - ko00000,ko02000 ABC transporter
HLLBMAHE_04041 0.0 ywiE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HLLBMAHE_04042 2.06e-159 narI 1.7.5.1 - C ko:K00374 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase (gamma
HLLBMAHE_04043 2.77e-122 narJ - - C ko:K00373 ko02020,map02020 ko00000,ko00001 nitrate reductase
HLLBMAHE_04044 0.0 narH 1.7.5.1 - C ko:K00371 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Nitrate reductase, beta
HLLBMAHE_04045 0.0 narG 1.7.5.1 - C ko:K00370 ko00910,ko01120,ko02020,map00910,map01120,map02020 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLLBMAHE_04046 5.02e-110 arfM - - T ko:K10914 ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111 ko00000,ko00001,ko03000 cyclic nucleotide binding
HLLBMAHE_04047 1.84e-179 ywiC - - S - - - YwiC-like protein
HLLBMAHE_04048 2.3e-168 fnr - - K - - - helix_turn_helix, cAMP Regulatory protein
HLLBMAHE_04049 8.44e-274 narK - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
HLLBMAHE_04050 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
HLLBMAHE_04051 4.64e-96 ywiB - - S - - - protein conserved in bacteria
HLLBMAHE_04052 3.71e-12 - - - S - - - Bacteriocin subtilosin A
HLLBMAHE_04053 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
HLLBMAHE_04055 1.5e-169 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
HLLBMAHE_04056 3.42e-297 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
HLLBMAHE_04057 3.29e-274 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
HLLBMAHE_04058 4.46e-180 - - - L - - - Peptidase, M16
HLLBMAHE_04059 6.5e-117 - - - L - - - Peptidase, M16
HLLBMAHE_04061 1.18e-315 ywhL - - CO - - - amine dehydrogenase activity
HLLBMAHE_04062 1.1e-273 ywhK - - CO - - - amine dehydrogenase activity
HLLBMAHE_04063 9.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HLLBMAHE_04065 2.76e-65 - - - S - - - Aminoacyl-tRNA editing domain
HLLBMAHE_04066 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HLLBMAHE_04067 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HLLBMAHE_04068 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
HLLBMAHE_04069 2.1e-64 - - - - - - - -
HLLBMAHE_04070 1.92e-123 ywhD - - S - - - YwhD family
HLLBMAHE_04071 5.45e-153 ywhC - - S - - - Peptidase family M50
HLLBMAHE_04072 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
HLLBMAHE_04073 1.76e-94 ywhA - - K - - - Transcriptional regulator
HLLBMAHE_04074 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HLLBMAHE_04076 8.75e-300 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
HLLBMAHE_04077 3.15e-103 yffB - - K - - - Transcriptional regulator
HLLBMAHE_04078 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
HLLBMAHE_04079 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
HLLBMAHE_04080 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
HLLBMAHE_04081 5.39e-145 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
HLLBMAHE_04082 2.39e-199 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
HLLBMAHE_04083 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HLLBMAHE_04084 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_04085 9.66e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
HLLBMAHE_04086 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
HLLBMAHE_04087 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
HLLBMAHE_04088 9e-297 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
HLLBMAHE_04089 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HLLBMAHE_04090 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HLLBMAHE_04091 6.34e-178 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HLLBMAHE_04092 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HLLBMAHE_04093 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HLLBMAHE_04094 6.3e-274 ywfA - - EGP - - - -transporter
HLLBMAHE_04095 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HLLBMAHE_04096 0.0 rocB - - E - - - arginine degradation protein
HLLBMAHE_04097 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
HLLBMAHE_04098 2.11e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
HLLBMAHE_04099 6.13e-100 - - - - - - - -
HLLBMAHE_04100 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
HLLBMAHE_04101 8.77e-202 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HLLBMAHE_04102 5.26e-233 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HLLBMAHE_04103 2.5e-176 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HLLBMAHE_04104 4.91e-241 spsG - - M - - - Spore Coat
HLLBMAHE_04105 2.58e-166 spsF - - M ko:K07257 - ko00000 Spore Coat
HLLBMAHE_04106 3.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
HLLBMAHE_04107 1.21e-209 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
HLLBMAHE_04108 6.44e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
HLLBMAHE_04109 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
HLLBMAHE_04110 1.15e-186 spsA - - M - - - Spore Coat
HLLBMAHE_04111 3.62e-112 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HLLBMAHE_04112 1.59e-78 ywdK - - S - - - small membrane protein
HLLBMAHE_04113 1.86e-303 ywdJ - - F - - - Xanthine uracil
HLLBMAHE_04114 2.18e-63 ywdI - - S - - - Family of unknown function (DUF5327)
HLLBMAHE_04115 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
HLLBMAHE_04116 9.47e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HLLBMAHE_04117 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
HLLBMAHE_04119 8.74e-146 ywdD - - - - - - -
HLLBMAHE_04120 7.92e-76 - - - K ko:K10947 - ko00000,ko03000 Transcriptional regulator PadR-like family
HLLBMAHE_04121 2.21e-187 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
HLLBMAHE_04122 6.19e-39 ywdA - - - - - - -
HLLBMAHE_04123 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
HLLBMAHE_04124 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_04125 2.91e-180 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
HLLBMAHE_04126 5.24e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HLLBMAHE_04128 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HLLBMAHE_04129 1.15e-236 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLLBMAHE_04130 1.98e-179 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
HLLBMAHE_04131 8.89e-269 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
HLLBMAHE_04132 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
HLLBMAHE_04133 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HLLBMAHE_04134 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
HLLBMAHE_04135 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HLLBMAHE_04136 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HLLBMAHE_04137 5.11e-49 ydaS - - S - - - membrane
HLLBMAHE_04138 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
HLLBMAHE_04139 1.12e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HLLBMAHE_04140 3.33e-77 gtcA - - S - - - GtrA-like protein
HLLBMAHE_04141 2.81e-157 ywcC - - K - - - transcriptional regulator
HLLBMAHE_04143 7.41e-65 ywcB - - S - - - Protein of unknown function, DUF485
HLLBMAHE_04144 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HLLBMAHE_04145 4.22e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
HLLBMAHE_04146 9.86e-177 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HLLBMAHE_04147 2.46e-85 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
HLLBMAHE_04148 1.7e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
HLLBMAHE_04149 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
HLLBMAHE_04150 7.69e-150 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HLLBMAHE_04151 3.25e-185 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HLLBMAHE_04152 2.7e-203 ywbI - - K - - - Transcriptional regulator
HLLBMAHE_04153 1.1e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HLLBMAHE_04154 1.21e-143 ywbG - - M - - - effector of murein hydrolase
HLLBMAHE_04155 1.29e-280 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
HLLBMAHE_04156 3.13e-38 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
HLLBMAHE_04157 1.02e-280 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
HLLBMAHE_04158 1.99e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
HLLBMAHE_04159 1.52e-105 ywbB - - S - - - Protein of unknown function (DUF2711)
HLLBMAHE_04160 1.66e-20 ywbB - - S - - - Protein of unknown function (DUF2711)
HLLBMAHE_04161 2.71e-314 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLLBMAHE_04162 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
HLLBMAHE_04163 2.4e-311 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_04164 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HLLBMAHE_04165 6.53e-217 gspA - - M - - - General stress
HLLBMAHE_04166 3.64e-160 ywaF - - S - - - Integral membrane protein
HLLBMAHE_04167 1.25e-114 ywaE - - K - - - Transcriptional regulator
HLLBMAHE_04168 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HLLBMAHE_04169 9.14e-317 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
HLLBMAHE_04170 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
HLLBMAHE_04171 7.55e-59 orfX1 - - L - - - Transposase
HLLBMAHE_04172 5.6e-173 - - - L - - - Integrase core domain
HLLBMAHE_04173 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
HLLBMAHE_04174 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_04175 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
HLLBMAHE_04176 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HLLBMAHE_04177 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HLLBMAHE_04178 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_04179 3.02e-82 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_04180 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
HLLBMAHE_04181 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HLLBMAHE_04182 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
HLLBMAHE_04183 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HLLBMAHE_04184 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
HLLBMAHE_04185 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
HLLBMAHE_04186 1.05e-26 yxzF - - - - - - -
HLLBMAHE_04187 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
HLLBMAHE_04188 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HLLBMAHE_04189 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
HLLBMAHE_04190 1.55e-176 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HLLBMAHE_04191 4.23e-213 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_04192 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
HLLBMAHE_04193 1.63e-39 - - - - - - - -
HLLBMAHE_04194 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
HLLBMAHE_04195 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
HLLBMAHE_04196 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
HLLBMAHE_04197 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HLLBMAHE_04198 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
HLLBMAHE_04199 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
HLLBMAHE_04200 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
HLLBMAHE_04201 2.24e-86 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HLLBMAHE_04202 9.68e-228 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
HLLBMAHE_04203 1.8e-306 cimH - - C - - - COG3493 Na citrate symporter
HLLBMAHE_04204 0.0 - - - O - - - Peptidase family M48
HLLBMAHE_04206 8.75e-198 yxkH - - G - - - Polysaccharide deacetylase
HLLBMAHE_04207 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
HLLBMAHE_04208 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
HLLBMAHE_04209 4.47e-107 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLLBMAHE_04210 2.33e-188 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLLBMAHE_04211 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
HLLBMAHE_04212 1.95e-99 yxkC - - S - - - Domain of unknown function (DUF4352)
HLLBMAHE_04213 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
HLLBMAHE_04214 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
HLLBMAHE_04215 2.16e-243 - - - T - - - Signal transduction histidine kinase
HLLBMAHE_04216 4.46e-147 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
HLLBMAHE_04217 1.06e-296 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
HLLBMAHE_04220 2.88e-111 yxjI - - S - - - LURP-one-related
HLLBMAHE_04221 8.66e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HLLBMAHE_04222 2.21e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
HLLBMAHE_04223 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HLLBMAHE_04224 6.9e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HLLBMAHE_04225 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HLLBMAHE_04226 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
HLLBMAHE_04227 1.1e-197 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
HLLBMAHE_04228 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLLBMAHE_04229 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
HLLBMAHE_04230 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
HLLBMAHE_04232 2.28e-63 yxiS - - - - - - -
HLLBMAHE_04233 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
HLLBMAHE_04234 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
HLLBMAHE_04235 3.06e-184 bglS - - M - - - licheninase activity
HLLBMAHE_04236 2.01e-176 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
HLLBMAHE_04237 3.59e-141 - - - - - - - -
HLLBMAHE_04238 4.94e-288 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
HLLBMAHE_04239 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HLLBMAHE_04240 3.67e-276 - - - E - - - GDSL-like Lipase/Acylhydrolase
HLLBMAHE_04243 4.06e-58 yxiJ - - S - - - YxiJ-like protein
HLLBMAHE_04246 1.86e-40 - - - - - - - -
HLLBMAHE_04247 8.21e-50 yxiI - - S - - - Protein of unknown function (DUF2716)
HLLBMAHE_04248 3.42e-173 - - - - - - - -
HLLBMAHE_04251 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
HLLBMAHE_04252 9.7e-68 yxxG - - - - - - -
HLLBMAHE_04253 4.67e-89 yxiG - - - - - - -
HLLBMAHE_04254 4.48e-58 - - - - - - - -
HLLBMAHE_04255 7.15e-28 - - - - - - - -
HLLBMAHE_04256 5.36e-120 - - - S - - - Protein of unknown function (DUF4240)
HLLBMAHE_04257 6.44e-178 - - - - - - - -
HLLBMAHE_04259 1.27e-69 - - - - - - - -
HLLBMAHE_04260 6.47e-100 wapA - - M - - - COG3209 Rhs family protein
HLLBMAHE_04261 3.29e-19 yxiJ - - S - - - YxiJ-like protein
HLLBMAHE_04262 0.0 wapA - - M - - - COG3209 Rhs family protein
HLLBMAHE_04263 1.99e-208 yxxF - - EG - - - EamA-like transporter family
HLLBMAHE_04264 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
HLLBMAHE_04265 2.02e-217 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_04266 1.99e-82 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_04267 1.25e-41 - - - - - - - -
HLLBMAHE_04268 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
HLLBMAHE_04269 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
HLLBMAHE_04270 3.27e-53 yxiC - - S - - - Family of unknown function (DUF5344)
HLLBMAHE_04271 6.24e-36 - - - S - - - Domain of unknown function (DUF5082)
HLLBMAHE_04272 1.51e-75 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
HLLBMAHE_04273 6.07e-130 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HLLBMAHE_04274 1.65e-95 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HLLBMAHE_04275 3.18e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HLLBMAHE_04276 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
HLLBMAHE_04277 1.11e-262 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HLLBMAHE_04278 8.3e-150 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HLLBMAHE_04279 2.02e-220 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HLLBMAHE_04280 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
HLLBMAHE_04281 1.49e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
HLLBMAHE_04282 1.87e-316 yxeQ - - S - - - MmgE/PrpD family
HLLBMAHE_04283 2.89e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
HLLBMAHE_04284 1.95e-170 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_04285 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
HLLBMAHE_04286 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
HLLBMAHE_04287 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HLLBMAHE_04288 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HLLBMAHE_04289 2.61e-235 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
HLLBMAHE_04290 5.69e-194 yxeH - - S - - - hydrolases of the HAD superfamily
HLLBMAHE_04293 7.32e-42 yxeE - - - - - - -
HLLBMAHE_04294 2.66e-28 yxeD - - - - - - -
HLLBMAHE_04295 7.94e-90 - - - - - - - -
HLLBMAHE_04296 1.62e-217 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLLBMAHE_04297 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
HLLBMAHE_04298 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
HLLBMAHE_04299 9.7e-88 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_04300 6.59e-67 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
HLLBMAHE_04301 9.03e-230 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_04302 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_04303 2.43e-205 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HLLBMAHE_04304 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HLLBMAHE_04305 8.87e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
HLLBMAHE_04306 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HLLBMAHE_04307 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
HLLBMAHE_04308 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HLLBMAHE_04309 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HLLBMAHE_04310 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HLLBMAHE_04311 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HLLBMAHE_04312 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HLLBMAHE_04314 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_04315 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
HLLBMAHE_04316 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
HLLBMAHE_04317 7.27e-55 - - - - - - - -
HLLBMAHE_04319 2.23e-17 - - - S - - - CGNR zinc finger
HLLBMAHE_04320 4.47e-103 - - - T - - - HPP family
HLLBMAHE_04321 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_04322 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HLLBMAHE_04323 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
HLLBMAHE_04325 1.7e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
HLLBMAHE_04326 1.24e-22 ygzD - - K ko:K07729 - ko00000,ko03000 transcriptional
HLLBMAHE_04330 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_04332 4.82e-294 - - - V ko:K20344 ko02010,ko02024,map02010,map02024 ko00000,ko00001,ko02000 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HLLBMAHE_04333 1.49e-207 - - - M ko:K20345 ko02024,map02024 ko00000,ko00001,ko02000 HlyD family secretion protein
HLLBMAHE_04335 7.39e-246 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
HLLBMAHE_04336 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
HLLBMAHE_04337 1.72e-229 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
HLLBMAHE_04338 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
HLLBMAHE_04339 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
HLLBMAHE_04340 1.04e-151 yxaC - - M - - - effector of murein hydrolase
HLLBMAHE_04341 3.4e-235 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
HLLBMAHE_04342 1.35e-262 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
HLLBMAHE_04343 2.56e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
HLLBMAHE_04344 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
HLLBMAHE_04345 1.38e-293 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
HLLBMAHE_04346 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HLLBMAHE_04347 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
HLLBMAHE_04348 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
HLLBMAHE_04349 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
HLLBMAHE_04350 1.15e-37 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
HLLBMAHE_04351 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_04352 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
HLLBMAHE_04353 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
HLLBMAHE_04354 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
HLLBMAHE_04355 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_04356 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
HLLBMAHE_04357 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
HLLBMAHE_04358 4.78e-152 - - - L - - - Bacterial dnaA protein
HLLBMAHE_04359 6.98e-279 - - - L - - - Transposase
HLLBMAHE_04360 2.64e-42 - - - - - - - -
HLLBMAHE_04361 0.0 - - - V - - - Abi-like protein
HLLBMAHE_04362 0.0 - - - L - - - Superfamily I DNA and RNA helicases
HLLBMAHE_04363 0.0 - - - L - - - AAA ATPase domain
HLLBMAHE_04364 6.23e-148 - - - S - - - HTH-like domain
HLLBMAHE_04365 1.07e-57 - - - S - - - transposition, DNA-mediated
HLLBMAHE_04367 3.99e-53 - - - - - - - -
HLLBMAHE_04368 1.51e-174 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
HLLBMAHE_04369 1.59e-65 - - - L - - - Transposase
HLLBMAHE_04370 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
HLLBMAHE_04372 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HLLBMAHE_04374 9.49e-89 - - - - - - - -
HLLBMAHE_04375 2.58e-297 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HLLBMAHE_04377 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
HLLBMAHE_04378 7.64e-255 yycP - - - - - - -
HLLBMAHE_04379 7.97e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HLLBMAHE_04380 3.04e-110 yycN - - K - - - Acetyltransferase
HLLBMAHE_04381 8.7e-239 - - - S - - - aspartate phosphatase
HLLBMAHE_04383 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
HLLBMAHE_04384 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
HLLBMAHE_04385 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
HLLBMAHE_04386 5.82e-20 - - - - - - - -
HLLBMAHE_04387 4.85e-119 - - - - - - - -
HLLBMAHE_04388 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
HLLBMAHE_04389 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HLLBMAHE_04390 2.31e-54 sdpR - - K - - - transcriptional
HLLBMAHE_04391 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HLLBMAHE_04392 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HLLBMAHE_04393 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HLLBMAHE_04394 3.44e-200 yycI - - S - - - protein conserved in bacteria
HLLBMAHE_04395 0.0 yycH - - S - - - protein conserved in bacteria
HLLBMAHE_04396 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
HLLBMAHE_04397 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HLLBMAHE_04402 3.02e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HLLBMAHE_04403 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_04404 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
HLLBMAHE_04405 2.87e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
HLLBMAHE_04407 1.89e-22 yycC - - K - - - YycC-like protein
HLLBMAHE_04408 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
HLLBMAHE_04409 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HLLBMAHE_04410 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
HLLBMAHE_04411 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
HLLBMAHE_04412 1.5e-204 yybS - - S - - - membrane
HLLBMAHE_04414 6.83e-109 cotF - - M ko:K06329 - ko00000 Spore coat protein
HLLBMAHE_04415 1.3e-87 yybR - - K - - - Transcriptional regulator
HLLBMAHE_04416 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
HLLBMAHE_04417 3.19e-90 - - - - - - - -
HLLBMAHE_04419 2.37e-306 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_04420 1.51e-121 - - - K - - - TipAS antibiotic-recognition domain
HLLBMAHE_04421 2.91e-183 - - - - - - - -
HLLBMAHE_04422 2.39e-85 - - - S - - - SnoaL-like domain
HLLBMAHE_04423 2.81e-162 yybG - - S - - - Pentapeptide repeat-containing protein
HLLBMAHE_04424 7.55e-59 orfX1 - - L - - - Transposase
HLLBMAHE_04425 1.13e-172 - - - L - - - Integrase core domain
HLLBMAHE_04426 6.02e-127 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
HLLBMAHE_04427 9.45e-84 - - - S - - - Metallo-beta-lactamase superfamily
HLLBMAHE_04428 4.54e-100 yybA - - K - - - transcriptional
HLLBMAHE_04429 2.44e-94 yjcF - - S - - - Acetyltransferase (GNAT) domain
HLLBMAHE_04430 1.74e-124 yyaS - - S ko:K07149 - ko00000 Membrane
HLLBMAHE_04431 7.8e-119 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
HLLBMAHE_04432 1.28e-86 - - - S - - - YjbR
HLLBMAHE_04433 2.44e-67 yyaP - - H - - - RibD C-terminal domain
HLLBMAHE_04434 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
HLLBMAHE_04435 2.59e-36 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HLLBMAHE_04436 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
HLLBMAHE_04437 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
HLLBMAHE_04438 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
HLLBMAHE_04439 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
HLLBMAHE_04440 1.05e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
HLLBMAHE_04441 4.69e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HLLBMAHE_04442 2.14e-154 ccpB - - K - - - Transcriptional regulator
HLLBMAHE_04443 1.32e-60 ccpB - - K - - - Transcriptional regulator
HLLBMAHE_04444 4.01e-185 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
HLLBMAHE_04445 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HLLBMAHE_04446 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HLLBMAHE_04447 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
HLLBMAHE_04448 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HLLBMAHE_04449 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HLLBMAHE_04450 7.41e-45 yyzM - - S - - - protein conserved in bacteria
HLLBMAHE_04451 5.34e-227 yyaD - - S - - - Membrane
HLLBMAHE_04452 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
HLLBMAHE_04453 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
HLLBMAHE_04454 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
HLLBMAHE_04455 3.77e-97 - - - S - - - Bacterial PH domain
HLLBMAHE_04456 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HLLBMAHE_04457 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HLLBMAHE_04458 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HLLBMAHE_04459 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HLLBMAHE_04460 4.32e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
HLLBMAHE_04461 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HLLBMAHE_04462 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HLLBMAHE_04466 4.75e-07 - - - - - - - -
HLLBMAHE_04468 1.33e-36 - - - - - - - -
HLLBMAHE_04474 1.25e-77 - - - - - - - -
HLLBMAHE_04480 1e-12 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_04481 5.07e-20 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
HLLBMAHE_04482 1.09e-199 - - - S - - - Domain of unknown function (DUF5068)
HLLBMAHE_04483 3.19e-42 - - - - - - - -
HLLBMAHE_04484 1.38e-56 - - - L - - - Initiator Replication protein
HLLBMAHE_04485 1.63e-06 - - - S - - - SEC-C motif
HLLBMAHE_04495 8.35e-11 - - - M - - - NlpC P60 family protein
HLLBMAHE_04498 5.86e-29 pilT - - NU ko:K02669 - ko00000,ko02035,ko02044 PFAM Type II secretion system protein E
HLLBMAHE_04510 3.07e-27 - - - K - - - Transcriptional regulator
HLLBMAHE_04511 4.39e-217 - - - L - - - TIGRFAM Transposase, IS605 OrfB, C-terminal
HLLBMAHE_04512 1.39e-37 - - - L - - - DnaD domain protein
HLLBMAHE_04514 0.000533 - - - K ko:K07075,ko:K15773 - ko00000,ko02048,ko03000 sequence-specific DNA binding
HLLBMAHE_04515 1.47e-67 ypuA - - S - - - Protein of unknown function (DUF1002)
HLLBMAHE_04526 2.6e-09 - - - - - - - -
HLLBMAHE_04527 4.66e-68 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
HLLBMAHE_04528 1.7e-177 - - - M - - - Psort location Cellwall, score
HLLBMAHE_04535 4.77e-16 - - - S - - - YolD-like protein
HLLBMAHE_04537 1.48e-34 - - - - - - - -
HLLBMAHE_04538 2.37e-47 - - - L ko:K03630 - ko00000 RadC-like JAB domain
HLLBMAHE_04540 8.48e-171 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_04544 4.71e-55 - - - L ko:K07491 - ko00000 Transposase IS200 like
HLLBMAHE_04545 1.16e-199 - - - L - - - TIGRFAM Transposase, IS605 OrfB, C-terminal
HLLBMAHE_04546 2.54e-53 nucA - - M - - - Deoxyribonuclease NucA/NucB
HLLBMAHE_04552 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_04555 5.68e-118 cysL - - K ko:K21900 - ko00000,ko03000 Bacterial regulatory helix-turn-helix protein, lysR family
HLLBMAHE_04556 3.65e-171 - - - S - - - Conserved hypothetical protein 698
HLLBMAHE_04557 8.41e-45 - - - T - - - AMP binding
HLLBMAHE_04558 1.84e-123 tnpR - - L - - - resolvase
HLLBMAHE_04559 0.0 - - - L - - - Transposase and inactivated derivatives, TnpA family
HLLBMAHE_04560 6.99e-09 - - - S ko:K09167 - ko00000 Bacterial PH domain
HLLBMAHE_04561 1.9e-50 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
HLLBMAHE_04565 6.48e-34 - - - S - - - Repressor of ComK
HLLBMAHE_04566 8.34e-26 - - - K ko:K06284 - ko00000,ko03000 SpoVT / AbrB like domain
HLLBMAHE_04571 4.03e-07 ftsK - - D ko:K03466 - ko00000,ko03036 DNA segregation ATPase FtsK SpoIIIE and related proteins
HLLBMAHE_04583 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_04586 8.99e-39 - - - V ko:K06877,ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
HLLBMAHE_04587 1.49e-112 - - - V ko:K06877,ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
HLLBMAHE_04589 1.39e-86 - - - - - - - -
HLLBMAHE_04590 7.26e-146 - - - L - - - Belongs to the 'phage' integrase family
HLLBMAHE_04591 1.24e-21 - - - - - - - -
HLLBMAHE_04597 4.64e-10 - - - - - - - -
HLLBMAHE_04598 1.25e-13 - - - S - - - YvrJ protein family
HLLBMAHE_04599 1.09e-64 yvrI - - K ko:K03093 - ko00000,ko03021 COG1191 DNA-directed RNA polymerase specialized sigma subunit
HLLBMAHE_04600 1.96e-17 - - - - - - - -
HLLBMAHE_04602 1.92e-19 - - - V - - - VanZ like family
HLLBMAHE_04603 6.11e-23 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
HLLBMAHE_04610 1.26e-113 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
HLLBMAHE_04612 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_04613 3.98e-101 - - - S - - - MepB protein
HLLBMAHE_04616 1.1e-111 - - - S - - - SMART Tetratricopeptide domain protein
HLLBMAHE_04620 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
HLLBMAHE_04633 1.19e-98 - - - S ko:K02004 - ko00000,ko00002,ko02000 bacteriocin-associated integral membrane protein
HLLBMAHE_04634 5.23e-85 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
HLLBMAHE_04643 3.65e-15 - - - - - - - -
HLLBMAHE_04644 2.73e-245 - - - L - - - transposase, IS605 OrfB family
HLLBMAHE_04645 3.1e-75 - - - L ko:K07491 - ko00000 transposase IS200-family protein
HLLBMAHE_04646 4.27e-114 - - - S - - - Fic/DOC family
HLLBMAHE_04648 1.55e-187 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
HLLBMAHE_04649 1.35e-245 - - - L - - - transposase, IS605 OrfB family
HLLBMAHE_04650 1.26e-74 - - - L ko:K07491 - ko00000 transposase IS200-family protein
HLLBMAHE_04651 3.6e-226 - - - L - - - Replication protein
HLLBMAHE_04654 4.06e-89 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
HLLBMAHE_04656 1.64e-38 - - - - - - - -
HLLBMAHE_04658 1.83e-82 - - - O - - - Heat shock 70 kDa protein
HLLBMAHE_04659 1.14e-15 - - - S - - - Helix-turn-helix domain
HLLBMAHE_04661 1.49e-197 - - - S - - - COG0433 Predicted ATPase
HLLBMAHE_04664 4.16e-08 - - - S - - - Conjugative transposon protein TcpC
HLLBMAHE_04667 2.89e-83 - - - S - - - AAA-like domain
HLLBMAHE_04669 4.97e-17 - - - M - - - Psort location CytoplasmicMembrane, score
HLLBMAHE_04671 5.82e-123 - - - M ko:K21471,ko:K21472 - ko00000,ko01000,ko01002,ko01011 lytic transglycosylase activity

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)