Read a JSON File

ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
HFAPHBKH_00001	1.01e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
HFAPHBKH_00002	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
HFAPHBKH_00003	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HFAPHBKH_00004	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HFAPHBKH_00005	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
HFAPHBKH_00006	1.03e-141	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFAPHBKH_00007	1e-17	-	-	-	-	-	-	-	-
HFAPHBKH_00008	2.08e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HFAPHBKH_00009	7.86e-162	cotB	-	-	-	ko:K06325	-	ko00000	-
HFAPHBKH_00010	4.33e-162	ywrJ	-	-	-	-	-	-	-
HFAPHBKH_00011	9.31e-279	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HFAPHBKH_00012	1.37e-217	alsR	-	-	K	-	-	-	LysR substrate binding domain
HFAPHBKH_00013	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
HFAPHBKH_00014	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
HFAPHBKH_00015	1.24e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
HFAPHBKH_00016	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
HFAPHBKH_00017	3.97e-119	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
HFAPHBKH_00018	1.22e-172	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
HFAPHBKH_00019	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFAPHBKH_00020	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HFAPHBKH_00021	3.12e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFAPHBKH_00022	8.06e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFAPHBKH_00023	1.68e-224	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HFAPHBKH_00024	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
HFAPHBKH_00025	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
HFAPHBKH_00026	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HFAPHBKH_00027	2.29e-29	ywtC	-	-	-	-	-	-	-
HFAPHBKH_00028	9.23e-303	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HFAPHBKH_00029	1.99e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HFAPHBKH_00030	3.53e-178	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00031	2.61e-314	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_00032	3.68e-256	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HFAPHBKH_00033	2.06e-239	gerBB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HFAPHBKH_00034	1.33e-181	gerBA	-	-	EG	ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFAPHBKH_00035	1e-101	gerBA	-	-	EG	ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFAPHBKH_00036	3.57e-236	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFAPHBKH_00037	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFAPHBKH_00038	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HFAPHBKH_00039	4.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HFAPHBKH_00040	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
HFAPHBKH_00041	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HFAPHBKH_00042	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HFAPHBKH_00044	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
HFAPHBKH_00045	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HFAPHBKH_00046	1.07e-14	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
HFAPHBKH_00047	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFAPHBKH_00048	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFAPHBKH_00049	4.48e-22	lytR	-	-	K	-	-	-	May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HFAPHBKH_00050	1.75e-149	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HFAPHBKH_00051	1.82e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFAPHBKH_00052	4.98e-256	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
HFAPHBKH_00053	1.16e-301	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFAPHBKH_00055	4.47e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
HFAPHBKH_00056	4.16e-137	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
HFAPHBKH_00057	1.33e-174	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HFAPHBKH_00058	7.15e-298	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
HFAPHBKH_00059	2.99e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HFAPHBKH_00061	4.26e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_00064	1.03e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
HFAPHBKH_00067	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00068	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
HFAPHBKH_00069	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HFAPHBKH_00070	2.92e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_00071	5.06e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00072	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HFAPHBKH_00073	2.06e-43	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
HFAPHBKH_00074	8.46e-158	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
HFAPHBKH_00075	6.15e-95	yvyF	-	-	S	-	-	-	flagellar protein
HFAPHBKH_00076	5.05e-52	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
HFAPHBKH_00077	3.5e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
HFAPHBKH_00078	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
HFAPHBKH_00079	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
HFAPHBKH_00080	6.92e-92	yviE	-	-	-	-	-	-	-
HFAPHBKH_00081	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HFAPHBKH_00082	4.29e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HFAPHBKH_00083	7.45e-148	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HFAPHBKH_00084	9.77e-71	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
HFAPHBKH_00085	2.21e-313	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HFAPHBKH_00086	6.02e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
HFAPHBKH_00087	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
HFAPHBKH_00088	2.46e-67	-	-	-	-	-	-	-	-
HFAPHBKH_00089	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFAPHBKH_00090	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFAPHBKH_00091	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFAPHBKH_00092	1.31e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFAPHBKH_00093	3.78e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HFAPHBKH_00094	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
HFAPHBKH_00095	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HFAPHBKH_00096	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HFAPHBKH_00097	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
HFAPHBKH_00098	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFAPHBKH_00099	3.03e-295	yvkA	-	-	P	-	-	-	-transporter
HFAPHBKH_00100	2.76e-129	yvkB	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00101	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
HFAPHBKH_00102	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00103	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFAPHBKH_00104	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFAPHBKH_00105	1.68e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HFAPHBKH_00106	2.25e-45	yvkN	-	-	-	-	-	-	-
HFAPHBKH_00107	8.09e-65	yvlA	-	-	-	-	-	-	-
HFAPHBKH_00108	5.8e-221	yvlB	-	-	S	-	-	-	Putative adhesin
HFAPHBKH_00109	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
HFAPHBKH_00110	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
HFAPHBKH_00111	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
HFAPHBKH_00112	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
HFAPHBKH_00113	2.03e-164	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFAPHBKH_00114	1.19e-279	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
HFAPHBKH_00115	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFAPHBKH_00116	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFAPHBKH_00117	3.05e-210	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
HFAPHBKH_00118	8.05e-149	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HFAPHBKH_00119	5.29e-121	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HFAPHBKH_00120	3.83e-154	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
HFAPHBKH_00121	1.44e-177	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
HFAPHBKH_00122	2.82e-280	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HFAPHBKH_00123	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HFAPHBKH_00124	1.43e-289	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFAPHBKH_00125	2.87e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
HFAPHBKH_00126	1.2e-148	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFAPHBKH_00127	1.88e-166	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HFAPHBKH_00128	3.97e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HFAPHBKH_00129	2.93e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
HFAPHBKH_00130	9.72e-104	-	-	-	-	-	-	-	-
HFAPHBKH_00131	2.62e-314	-	-	-	-	-	-	-	-
HFAPHBKH_00133	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
HFAPHBKH_00134	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
HFAPHBKH_00135	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
HFAPHBKH_00136	3.89e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFAPHBKH_00137	9.76e-117	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HFAPHBKH_00138	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
HFAPHBKH_00139	6.72e-227	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
HFAPHBKH_00140	3.63e-220	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
HFAPHBKH_00141	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
HFAPHBKH_00142	2.3e-182	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
HFAPHBKH_00143	4.67e-172	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_00144	2.78e-251	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
HFAPHBKH_00145	3.67e-180	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_00146	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
HFAPHBKH_00147	5.45e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFAPHBKH_00148	1.07e-136	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HFAPHBKH_00149	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HFAPHBKH_00150	1.27e-39	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
HFAPHBKH_00151	2.66e-137	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
HFAPHBKH_00152	6.55e-223	yvdE	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00153	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
HFAPHBKH_00154	2.83e-300	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HFAPHBKH_00155	2.88e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HFAPHBKH_00156	2.29e-188	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HFAPHBKH_00157	1.02e-199	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HFAPHBKH_00158	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
HFAPHBKH_00159	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFAPHBKH_00160	7.59e-147	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFAPHBKH_00161	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFAPHBKH_00163	4.53e-95	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
HFAPHBKH_00164	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
HFAPHBKH_00165	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HFAPHBKH_00166	4.76e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00167	0.0	ybeC	-	-	E	-	-	-	amino acid
HFAPHBKH_00168	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HFAPHBKH_00169	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
HFAPHBKH_00170	3.77e-79	pbpE	-	-	V	-	-	-	Beta-lactamase
HFAPHBKH_00171	2.17e-224	pbpE	-	-	V	-	-	-	Beta-lactamase
HFAPHBKH_00172	2.3e-158	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
HFAPHBKH_00173	1.27e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HFAPHBKH_00174	1.18e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
HFAPHBKH_00175	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
HFAPHBKH_00177	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
HFAPHBKH_00178	2.07e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
HFAPHBKH_00179	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HFAPHBKH_00180	1.6e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HFAPHBKH_00181	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HFAPHBKH_00182	2.49e-278	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
HFAPHBKH_00183	6.94e-199	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFAPHBKH_00184	8.38e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFAPHBKH_00185	7.25e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
HFAPHBKH_00186	3.35e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
HFAPHBKH_00187	9.86e-262	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
HFAPHBKH_00188	5.33e-243	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFAPHBKH_00189	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFAPHBKH_00190	2.62e-138	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HFAPHBKH_00191	3.33e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
HFAPHBKH_00192	1.5e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
HFAPHBKH_00193	5.09e-239	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
HFAPHBKH_00194	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
HFAPHBKH_00195	2.75e-303	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HFAPHBKH_00196	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFAPHBKH_00197	5.87e-147	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
HFAPHBKH_00198	6.96e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_00199	3.8e-291	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
HFAPHBKH_00200	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
HFAPHBKH_00201	6.34e-193	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
HFAPHBKH_00202	3.31e-251	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HFAPHBKH_00203	1.2e-245	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
HFAPHBKH_00204	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
HFAPHBKH_00205	1.21e-255	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
HFAPHBKH_00206	2.83e-198	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
HFAPHBKH_00207	1.83e-203	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
HFAPHBKH_00208	8.31e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HFAPHBKH_00209	3.79e-252	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_00210	2.52e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_00211	8.72e-173	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HFAPHBKH_00212	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HFAPHBKH_00213	7.7e-168	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HFAPHBKH_00214	2.7e-187	-	-	-	S	-	-	-	Glycosyl hydrolase
HFAPHBKH_00215	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_00216	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_00217	1.99e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00218	6.01e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFAPHBKH_00219	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
HFAPHBKH_00220	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_00221	4.01e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HFAPHBKH_00222	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFAPHBKH_00223	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
HFAPHBKH_00224	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFAPHBKH_00225	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
HFAPHBKH_00226	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFAPHBKH_00227	1.18e-97	yvbK	-	-	K	-	-	-	acetyltransferase
HFAPHBKH_00228	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
HFAPHBKH_00229	2.28e-156	yvbI	-	-	M	-	-	-	Membrane
HFAPHBKH_00230	3.31e-103	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
HFAPHBKH_00231	1.32e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
HFAPHBKH_00232	6.82e-128	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HFAPHBKH_00233	3.23e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HFAPHBKH_00234	3.8e-143	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFAPHBKH_00235	4.28e-222	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFAPHBKH_00236	1.13e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFAPHBKH_00237	3.28e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
HFAPHBKH_00238	1.73e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HFAPHBKH_00239	1.55e-142	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFAPHBKH_00240	1.13e-218	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HFAPHBKH_00241	9.2e-144	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
HFAPHBKH_00242	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00243	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
HFAPHBKH_00244	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HFAPHBKH_00245	6.83e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
HFAPHBKH_00246	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
HFAPHBKH_00247	2.84e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
HFAPHBKH_00248	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
HFAPHBKH_00249	6.92e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
HFAPHBKH_00250	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFAPHBKH_00251	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HFAPHBKH_00253	3.67e-155	-	-	-	S	-	-	-	Phage integrase family
HFAPHBKH_00254	5.28e-79	-	-	-	-	-	-	-	-
HFAPHBKH_00257	9.99e-59	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFAPHBKH_00258	2.6e-09	-	-	-	T	ko:K21405	-	ko00000,ko03000	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HFAPHBKH_00261	1.81e-114	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
HFAPHBKH_00262	1.04e-21	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
HFAPHBKH_00263	1.76e-10	-	-	-	-	-	-	-	-
HFAPHBKH_00266	2.78e-08	-	-	-	-	-	-	-	-
HFAPHBKH_00273	8.04e-54	-	-	-	S	-	-	-	dUTPase
HFAPHBKH_00276	7.89e-68	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HFAPHBKH_00277	1.6e-94	-	-	-	L	-	-	-	Phage integrase family
HFAPHBKH_00279	1.38e-19	-	-	-	-	-	-	-	-
HFAPHBKH_00281	7.85e-84	-	-	-	S	-	-	-	HNH endonuclease
HFAPHBKH_00282	3.27e-27	-	-	-	-	-	-	-	-
HFAPHBKH_00283	2.87e-89	-	-	-	S	-	-	-	Phage terminase, small subunit
HFAPHBKH_00284	4.13e-279	-	-	-	S	-	-	-	Phage Terminase
HFAPHBKH_00285	5.41e-14	-	-	-	-	-	-	-	-
HFAPHBKH_00286	3.21e-271	-	-	-	S	-	-	-	Phage portal protein
HFAPHBKH_00287	9.36e-135	-	-	-	S	-	-	-	peptidase activity
HFAPHBKH_00288	2.18e-230	-	-	-	S	-	-	-	capsid protein
HFAPHBKH_00289	7.93e-09	-	-	-	-	-	-	-	-
HFAPHBKH_00290	7.91e-39	-	-	-	-	-	-	-	-
HFAPHBKH_00291	5.25e-34	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
HFAPHBKH_00292	4.59e-64	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFAPHBKH_00293	9.75e-79	-	-	-	-	-	-	-	-
HFAPHBKH_00294	1.58e-36	-	-	-	-	-	-	-	-
HFAPHBKH_00295	4.09e-16	-	-	-	-	-	-	-	-
HFAPHBKH_00296	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
HFAPHBKH_00297	1.96e-141	-	-	-	S	-	-	-	Phage tail protein
HFAPHBKH_00298	1.14e-307	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HFAPHBKH_00299	0.0	-	-	-	-	-	-	-	-
HFAPHBKH_00300	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
HFAPHBKH_00301	1.19e-260	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
HFAPHBKH_00302	1.38e-60	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFAPHBKH_00303	5.2e-292	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
HFAPHBKH_00304	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HFAPHBKH_00305	4.73e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
HFAPHBKH_00306	4.44e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
HFAPHBKH_00307	0.0	ycgA	-	-	S	-	-	-	Membrane
HFAPHBKH_00308	7.79e-105	ycgB	-	-	-	-	-	-	-
HFAPHBKH_00309	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HFAPHBKH_00310	7.37e-121	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
HFAPHBKH_00311	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
HFAPHBKH_00312	2.38e-82	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFAPHBKH_00313	1.33e-268	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
HFAPHBKH_00314	2.07e-192	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
HFAPHBKH_00315	8.63e-97	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_00316	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
HFAPHBKH_00317	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFAPHBKH_00318	1.08e-139	tmrB	-	-	S	-	-	-	AAA domain
HFAPHBKH_00319	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HFAPHBKH_00320	4.85e-182	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
HFAPHBKH_00321	3.64e-224	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
HFAPHBKH_00322	7.75e-232	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
HFAPHBKH_00323	1.29e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
HFAPHBKH_00324	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HFAPHBKH_00325	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HFAPHBKH_00326	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFAPHBKH_00327	6.5e-287	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
HFAPHBKH_00328	7.72e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
HFAPHBKH_00329	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
HFAPHBKH_00330	7.22e-191	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
HFAPHBKH_00331	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
HFAPHBKH_00332	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HFAPHBKH_00333	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
HFAPHBKH_00334	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFAPHBKH_00335	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFAPHBKH_00336	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
HFAPHBKH_00337	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
HFAPHBKH_00338	2.21e-150	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
HFAPHBKH_00339	1.79e-85	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
HFAPHBKH_00340	2.72e-141	yciC	-	-	S	-	-	-	GTPases (G3E family)
HFAPHBKH_00341	2.26e-123	yciC	-	-	S	-	-	-	GTPases (G3E family)
HFAPHBKH_00342	3.35e-146	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFAPHBKH_00343	1.03e-184	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HFAPHBKH_00346	1.11e-96	yckC	-	-	S	-	-	-	membrane
HFAPHBKH_00347	1.38e-66	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
HFAPHBKH_00348	1.06e-57	-	-	-	K	-	-	-	MarR family
HFAPHBKH_00349	2.49e-27	-	-	-	-	-	-	-	-
HFAPHBKH_00350	2.13e-113	-	-	-	S	-	-	-	AAA domain
HFAPHBKH_00351	2.42e-27	-	-	-	S	-	-	-	AAA domain
HFAPHBKH_00352	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFAPHBKH_00353	3.36e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
HFAPHBKH_00354	6.53e-99	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HFAPHBKH_00355	3.11e-73	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00356	9.46e-163	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00357	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
HFAPHBKH_00358	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
HFAPHBKH_00359	6.05e-86	hxlR	-	-	K	-	-	-	transcriptional
HFAPHBKH_00360	0.0	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFAPHBKH_00361	0.0	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFAPHBKH_00362	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
HFAPHBKH_00363	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
HFAPHBKH_00364	1.41e-284	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFAPHBKH_00365	1.48e-122	-	-	-	S	-	-	-	YcxB-like protein
HFAPHBKH_00366	1.17e-198	ycxC	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_00367	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
HFAPHBKH_00368	8.24e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
HFAPHBKH_00369	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
HFAPHBKH_00370	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFAPHBKH_00371	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFAPHBKH_00372	4.3e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
HFAPHBKH_00373	1.25e-207	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
HFAPHBKH_00374	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HFAPHBKH_00375	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HFAPHBKH_00376	4.02e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
HFAPHBKH_00377	6.45e-55	yclD	-	-	-	-	-	-	-
HFAPHBKH_00378	6.42e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
HFAPHBKH_00379	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
HFAPHBKH_00380	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
HFAPHBKH_00382	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HFAPHBKH_00383	1.22e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
HFAPHBKH_00384	4.73e-247	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
HFAPHBKH_00385	1.38e-154	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
HFAPHBKH_00386	7.57e-278	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
HFAPHBKH_00387	5.43e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_00388	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HFAPHBKH_00389	2.18e-97	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFAPHBKH_00391	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HFAPHBKH_00392	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFAPHBKH_00394	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_00395	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_00396	5.63e-176	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_00397	1.4e-213	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
HFAPHBKH_00398	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
HFAPHBKH_00399	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00400	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HFAPHBKH_00401	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
HFAPHBKH_00402	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFAPHBKH_00403	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFAPHBKH_00404	3.26e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFAPHBKH_00405	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFAPHBKH_00406	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
HFAPHBKH_00407	1.39e-185	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_00408	1.34e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00409	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
HFAPHBKH_00410	2.03e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFAPHBKH_00411	1.34e-74	-	-	-	-	-	-	-	-
HFAPHBKH_00412	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
HFAPHBKH_00413	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HFAPHBKH_00414	2.34e-263	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
HFAPHBKH_00415	5.86e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
HFAPHBKH_00417	4.68e-92	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFAPHBKH_00418	9.88e-27	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
HFAPHBKH_00419	2.29e-88	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
HFAPHBKH_00421	3.15e-176	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
HFAPHBKH_00422	4.46e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
HFAPHBKH_00423	1.32e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
HFAPHBKH_00424	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
HFAPHBKH_00425	2.8e-170	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
HFAPHBKH_00426	3.31e-237	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
HFAPHBKH_00427	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00428	1.2e-153	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
HFAPHBKH_00430	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
HFAPHBKH_00431	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
HFAPHBKH_00432	3.5e-219	ycsN	-	-	S	-	-	-	Oxidoreductase
HFAPHBKH_00433	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
HFAPHBKH_00434	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
HFAPHBKH_00435	4.09e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
HFAPHBKH_00436	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_00437	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
HFAPHBKH_00438	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFAPHBKH_00439	6.13e-100	ydaG	-	-	S	-	-	-	general stress protein
HFAPHBKH_00440	5.35e-178	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HFAPHBKH_00441	3.12e-61	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
HFAPHBKH_00442	1.61e-97	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
HFAPHBKH_00443	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFAPHBKH_00444	7.58e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HFAPHBKH_00445	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
HFAPHBKH_00448	1.84e-34	-	-	-	-	-	-	-	-
HFAPHBKH_00449	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
HFAPHBKH_00451	6.14e-53	-	-	-	-	-	-	-	-
HFAPHBKH_00452	7.87e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
HFAPHBKH_00453	1.67e-42	ydaS	-	-	S	-	-	-	membrane
HFAPHBKH_00454	7.54e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HFAPHBKH_00455	1.23e-189	ydbA	-	-	P	-	-	-	EcsC protein family
HFAPHBKH_00456	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
HFAPHBKH_00457	2.17e-78	ydbB	-	-	G	-	-	-	Cupin domain
HFAPHBKH_00458	3.66e-82	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
HFAPHBKH_00459	2.61e-196	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
HFAPHBKH_00460	1.49e-252	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HFAPHBKH_00461	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFAPHBKH_00462	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HFAPHBKH_00463	1.8e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFAPHBKH_00464	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
HFAPHBKH_00465	2.28e-219	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_00466	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFAPHBKH_00467	3.12e-68	ydbL	-	-	-	-	-	-	-
HFAPHBKH_00468	5.03e-278	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
HFAPHBKH_00469	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
HFAPHBKH_00471	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFAPHBKH_00472	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
HFAPHBKH_00473	3.58e-257	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
HFAPHBKH_00474	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFAPHBKH_00475	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFAPHBKH_00476	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
HFAPHBKH_00477	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
HFAPHBKH_00478	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
HFAPHBKH_00479	1.54e-75	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFAPHBKH_00480	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
HFAPHBKH_00481	2.07e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFAPHBKH_00482	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HFAPHBKH_00483	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
HFAPHBKH_00484	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
HFAPHBKH_00485	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
HFAPHBKH_00486	2.45e-89	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HFAPHBKH_00487	1.31e-243	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
HFAPHBKH_00488	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
HFAPHBKH_00489	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HFAPHBKH_00490	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_00491	1.08e-140	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
HFAPHBKH_00494	4.42e-105	ydcG	-	-	S	-	-	-	EVE domain
HFAPHBKH_00495	1.79e-100	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFAPHBKH_00496	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
HFAPHBKH_00497	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
HFAPHBKH_00505	5.14e-269	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFAPHBKH_00506	1.65e-118	-	-	-	E	-	-	-	IrrE N-terminal-like domain
HFAPHBKH_00507	1.91e-81	-	-	-	K	-	-	-	Transcriptional
HFAPHBKH_00508	8.96e-24	-	-	-	-	-	-	-	-
HFAPHBKH_00509	1.35e-55	-	-	-	-	-	-	-	-
HFAPHBKH_00511	1.84e-83	-	-	-	S	-	-	-	Bacterial protein of unknown function (DUF961)
HFAPHBKH_00512	0.0	ydcQ	-	-	D	ko:K03466	-	ko00000,ko03036	Ftsk spoiiie family protein
HFAPHBKH_00513	2.58e-254	nicK	-	-	L	ko:K07467	-	ko00000	Replication initiation factor
HFAPHBKH_00514	2.68e-23	-	-	-	S	-	-	-	Domain of Unknown Function with PDB structure (DUF3850)
HFAPHBKH_00517	2.49e-63	yddA	-	-	-	-	-	-	-
HFAPHBKH_00518	1.29e-223	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
HFAPHBKH_00519	9.78e-54	yddC	-	-	-	-	-	-	-
HFAPHBKH_00520	1.7e-118	yddD	-	-	S	-	-	-	TcpE family
HFAPHBKH_00521	0.0	yddE	-	-	S	-	-	-	AAA-like domain
HFAPHBKH_00522	3.29e-73	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
HFAPHBKH_00523	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
HFAPHBKH_00524	1.56e-128	-	-	-	-	-	-	-	-
HFAPHBKH_00525	2.82e-235	yddH	-	-	M	-	-	-	Lysozyme-like
HFAPHBKH_00526	1.11e-111	yddI	-	-	-	-	-	-	-
HFAPHBKH_00527	5.28e-83	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HFAPHBKH_00528	4.67e-90	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_00530	5.32e-43	-	-	-	G	-	-	-	Toxic component of a toxin-antitoxin (TA) module. An RNase
HFAPHBKH_00531	4.81e-95	-	-	-	T	-	-	-	NACHT domain
HFAPHBKH_00532	4.46e-153	-	-	-	E	-	-	-	amino acid
HFAPHBKH_00533	9.13e-135	ywqM	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00534	4.64e-95	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_00535	9.99e-59	-	-	-	-	-	-	-	-
HFAPHBKH_00536	2.79e-39	-	-	-	S	-	-	-	LXG domain of WXG superfamily
HFAPHBKH_00537	2.64e-35	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_00538	1.38e-66	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
HFAPHBKH_00539	2.09e-103	-	-	-	-	-	-	-	-
HFAPHBKH_00540	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
HFAPHBKH_00541	8.62e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFAPHBKH_00542	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFAPHBKH_00543	5.33e-85	-	-	-	-	-	-	-	-
HFAPHBKH_00544	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
HFAPHBKH_00546	3.48e-43	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFAPHBKH_00547	3.95e-23	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFAPHBKH_00548	2.75e-31	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFAPHBKH_00550	1.91e-146	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
HFAPHBKH_00551	1.21e-61	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
HFAPHBKH_00552	8.01e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
HFAPHBKH_00553	4.32e-279	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFAPHBKH_00554	3.82e-271	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFAPHBKH_00555	2.6e-175	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
HFAPHBKH_00556	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
HFAPHBKH_00557	7.08e-72	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFAPHBKH_00558	6.31e-51	-	-	-	-	-	-	-	-
HFAPHBKH_00559	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFAPHBKH_00560	1.88e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
HFAPHBKH_00563	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HFAPHBKH_00565	1.51e-18	cotW	-	-	-	ko:K06341	-	ko00000	-
HFAPHBKH_00566	1.03e-62	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
HFAPHBKH_00567	3.12e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
HFAPHBKH_00568	4.57e-108	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
HFAPHBKH_00569	2.09e-103	yjbX	-	-	S	-	-	-	Spore coat protein
HFAPHBKH_00570	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
HFAPHBKH_00571	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFAPHBKH_00572	2.41e-235	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HFAPHBKH_00573	1.86e-171	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HFAPHBKH_00574	2.56e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
HFAPHBKH_00575	1.73e-272	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
HFAPHBKH_00576	4.49e-136	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
HFAPHBKH_00577	1.91e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFAPHBKH_00578	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFAPHBKH_00579	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HFAPHBKH_00580	3.01e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFAPHBKH_00581	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFAPHBKH_00582	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
HFAPHBKH_00583	4.41e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
HFAPHBKH_00584	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00585	1.03e-121	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFAPHBKH_00586	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
HFAPHBKH_00587	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HFAPHBKH_00589	2.68e-28	-	-	-	-	-	-	-	-
HFAPHBKH_00590	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
HFAPHBKH_00591	1.78e-281	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
HFAPHBKH_00592	3.98e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HFAPHBKH_00593	4.1e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
HFAPHBKH_00594	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFAPHBKH_00595	8.88e-132	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFAPHBKH_00596	1.43e-268	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFAPHBKH_00597	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_00598	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_00599	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFAPHBKH_00600	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFAPHBKH_00601	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFAPHBKH_00602	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
HFAPHBKH_00603	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
HFAPHBKH_00604	8.44e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFAPHBKH_00605	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFAPHBKH_00606	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
HFAPHBKH_00607	2.07e-237	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_00608	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_00609	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
HFAPHBKH_00610	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFAPHBKH_00611	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFAPHBKH_00612	2.67e-38	yjzB	-	-	-	-	-	-	-
HFAPHBKH_00613	2.98e-13	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
HFAPHBKH_00614	3.7e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
HFAPHBKH_00615	6.08e-131	yjaV	-	-	-	-	-	-	-
HFAPHBKH_00616	2.42e-182	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
HFAPHBKH_00617	1.53e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
HFAPHBKH_00618	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
HFAPHBKH_00620	1.52e-209	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HFAPHBKH_00621	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
HFAPHBKH_00622	6.46e-265	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HFAPHBKH_00623	1.11e-102	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HFAPHBKH_00624	2.32e-95	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
HFAPHBKH_00625	4.16e-200	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
HFAPHBKH_00626	6.65e-280	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFAPHBKH_00627	9.7e-168	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFAPHBKH_00628	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
HFAPHBKH_00629	4.74e-37	-	-	-	-	-	-	-	-
HFAPHBKH_00630	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HFAPHBKH_00632	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HFAPHBKH_00633	7.27e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
HFAPHBKH_00634	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
HFAPHBKH_00635	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
HFAPHBKH_00636	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
HFAPHBKH_00637	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFAPHBKH_00638	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFAPHBKH_00639	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFAPHBKH_00640	1.02e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFAPHBKH_00641	1.24e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFAPHBKH_00642	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFAPHBKH_00643	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00644	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HFAPHBKH_00645	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFAPHBKH_00646	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
HFAPHBKH_00647	1.08e-148	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
HFAPHBKH_00648	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
HFAPHBKH_00649	7.65e-257	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
HFAPHBKH_00650	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
HFAPHBKH_00651	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
HFAPHBKH_00652	3.29e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
HFAPHBKH_00653	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
HFAPHBKH_00654	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
HFAPHBKH_00655	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFAPHBKH_00656	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HFAPHBKH_00657	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
HFAPHBKH_00658	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
HFAPHBKH_00659	1.48e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
HFAPHBKH_00660	5.18e-81	yqhP	-	-	-	-	-	-	-
HFAPHBKH_00661	1.41e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HFAPHBKH_00662	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HFAPHBKH_00663	8.8e-202	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HFAPHBKH_00664	7.5e-83	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
HFAPHBKH_00665	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HFAPHBKH_00666	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HFAPHBKH_00667	2.72e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
HFAPHBKH_00668	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HFAPHBKH_00669	1.52e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
HFAPHBKH_00670	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
HFAPHBKH_00671	3.69e-72	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
HFAPHBKH_00672	3.67e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
HFAPHBKH_00673	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
HFAPHBKH_00674	9.33e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
HFAPHBKH_00675	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HFAPHBKH_00676	2.84e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
HFAPHBKH_00677	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
HFAPHBKH_00678	1.01e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
HFAPHBKH_00679	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
HFAPHBKH_00680	1.13e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
HFAPHBKH_00681	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
HFAPHBKH_00682	7.16e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
HFAPHBKH_00683	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HFAPHBKH_00684	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HFAPHBKH_00685	8.73e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
HFAPHBKH_00686	2.01e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFAPHBKH_00687	4.82e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFAPHBKH_00689	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
HFAPHBKH_00690	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
HFAPHBKH_00691	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
HFAPHBKH_00692	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
HFAPHBKH_00693	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
HFAPHBKH_00694	2.69e-256	yqgU	-	-	-	-	-	-	-
HFAPHBKH_00695	3.55e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
HFAPHBKH_00696	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HFAPHBKH_00697	3.28e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
HFAPHBKH_00698	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
HFAPHBKH_00699	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
HFAPHBKH_00700	3.38e-14	yqgO	-	-	-	-	-	-	-
HFAPHBKH_00701	4.62e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFAPHBKH_00702	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFAPHBKH_00703	1.94e-248	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
HFAPHBKH_00705	2.81e-67	yqzD	-	-	-	-	-	-	-
HFAPHBKH_00706	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
HFAPHBKH_00707	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFAPHBKH_00708	1.14e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFAPHBKH_00709	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
HFAPHBKH_00710	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
HFAPHBKH_00711	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
HFAPHBKH_00712	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
HFAPHBKH_00713	8.92e-290	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
HFAPHBKH_00714	1.31e-147	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
HFAPHBKH_00715	1.17e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
HFAPHBKH_00716	2.74e-168	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
HFAPHBKH_00717	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
HFAPHBKH_00718	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HFAPHBKH_00719	2.04e-81	yqfX	-	-	S	-	-	-	membrane
HFAPHBKH_00720	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
HFAPHBKH_00721	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
HFAPHBKH_00722	2.21e-198	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFAPHBKH_00723	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
HFAPHBKH_00724	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HFAPHBKH_00725	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFAPHBKH_00726	1.05e-48	yqfQ	-	-	S	-	-	-	YqfQ-like protein
HFAPHBKH_00727	1.01e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HFAPHBKH_00728	2.44e-265	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFAPHBKH_00729	1.98e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
HFAPHBKH_00730	2.29e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
HFAPHBKH_00731	2.79e-254	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFAPHBKH_00732	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFAPHBKH_00733	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
HFAPHBKH_00734	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HFAPHBKH_00735	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
HFAPHBKH_00736	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
HFAPHBKH_00737	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
HFAPHBKH_00738	2.14e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
HFAPHBKH_00739	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
HFAPHBKH_00740	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFAPHBKH_00741	5.52e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HFAPHBKH_00742	3.34e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
HFAPHBKH_00743	1.75e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFAPHBKH_00744	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
HFAPHBKH_00746	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
HFAPHBKH_00747	8.52e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
HFAPHBKH_00748	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
HFAPHBKH_00749	2.23e-56	yqfB	-	-	-	-	-	-	-
HFAPHBKH_00750	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
HFAPHBKH_00751	3.78e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
HFAPHBKH_00752	4.53e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
HFAPHBKH_00753	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
HFAPHBKH_00754	3.26e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
HFAPHBKH_00755	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
HFAPHBKH_00756	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFAPHBKH_00757	2.29e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
HFAPHBKH_00758	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFAPHBKH_00759	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
HFAPHBKH_00760	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFAPHBKH_00761	3.88e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFAPHBKH_00762	1.68e-275	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
HFAPHBKH_00763	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFAPHBKH_00764	2.37e-68	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
HFAPHBKH_00765	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
HFAPHBKH_00766	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HFAPHBKH_00767	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
HFAPHBKH_00768	2.35e-243	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
HFAPHBKH_00769	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
HFAPHBKH_00770	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
HFAPHBKH_00771	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
HFAPHBKH_00772	3.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
HFAPHBKH_00773	1.1e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFAPHBKH_00774	7.73e-176	yqeM	-	-	Q	-	-	-	Methyltransferase
HFAPHBKH_00775	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFAPHBKH_00776	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
HFAPHBKH_00777	5.83e-140	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFAPHBKH_00778	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
HFAPHBKH_00779	4.01e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFAPHBKH_00780	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HFAPHBKH_00781	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
HFAPHBKH_00783	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFAPHBKH_00784	2.3e-174	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HFAPHBKH_00785	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
HFAPHBKH_00786	7.31e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
HFAPHBKH_00787	7.4e-168	-	-	-	-	-	-	-	-
HFAPHBKH_00788	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
HFAPHBKH_00789	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_00790	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFAPHBKH_00791	1.14e-197	yybE	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00792	7.09e-88	-	-	-	K	-	-	-	Glyoxalase bleomycin resistance protein dioxygenase
HFAPHBKH_00794	4.93e-266	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
HFAPHBKH_00795	3.2e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HFAPHBKH_00796	1.72e-221	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_00797	3.4e-49	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_00799	5.52e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HFAPHBKH_00800	1.1e-20	-	-	-	S	-	-	-	SMI1 / KNR4 family
HFAPHBKH_00801	5.24e-60	-	-	-	-	-	-	-	-
HFAPHBKH_00804	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
HFAPHBKH_00805	1.55e-140	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_00806	3.75e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_00808	1.12e-103	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFAPHBKH_00809	1.23e-157	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
HFAPHBKH_00810	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
HFAPHBKH_00811	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
HFAPHBKH_00812	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFAPHBKH_00813	9.99e-197	-	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_00814	8.66e-186	-	-	-	J	-	-	-	GNAT acetyltransferase
HFAPHBKH_00815	3.38e-292	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HFAPHBKH_00816	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
HFAPHBKH_00817	9.32e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFAPHBKH_00818	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
HFAPHBKH_00819	1.37e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
HFAPHBKH_00820	1.04e-69	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
HFAPHBKH_00821	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFAPHBKH_00822	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
HFAPHBKH_00823	2.44e-110	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
HFAPHBKH_00824	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
HFAPHBKH_00825	2.51e-36	-	-	-	S	-	-	-	SNARE associated Golgi protein
HFAPHBKH_00826	3.64e-142	-	-	-	-	-	-	-	-
HFAPHBKH_00827	5.75e-135	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
HFAPHBKH_00828	1.12e-70	ydeH	-	-	-	-	-	-	-
HFAPHBKH_00829	1.73e-236	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HFAPHBKH_00830	3.74e-24	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
HFAPHBKH_00831	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFAPHBKH_00832	7.62e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
HFAPHBKH_00833	5.34e-219	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFAPHBKH_00834	2.44e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
HFAPHBKH_00835	4.54e-176	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HFAPHBKH_00836	3.57e-103	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
HFAPHBKH_00837	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
HFAPHBKH_00838	3.49e-145	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
HFAPHBKH_00842	2.98e-53	-	-	-	-	-	-	-	-
HFAPHBKH_00843	1.54e-46	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
HFAPHBKH_00844	4.95e-97	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_00845	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
HFAPHBKH_00846	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HFAPHBKH_00847	1.22e-277	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
HFAPHBKH_00848	1.38e-123	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
HFAPHBKH_00849	2.88e-141	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
HFAPHBKH_00850	1.27e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
HFAPHBKH_00851	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_00852	5.78e-288	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HFAPHBKH_00853	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
HFAPHBKH_00854	2.59e-227	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
HFAPHBKH_00855	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFAPHBKH_00856	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
HFAPHBKH_00857	1.7e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
HFAPHBKH_00858	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
HFAPHBKH_00859	1.03e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
HFAPHBKH_00860	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
HFAPHBKH_00861	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
HFAPHBKH_00862	1.93e-267	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
HFAPHBKH_00863	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HFAPHBKH_00864	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
HFAPHBKH_00865	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
HFAPHBKH_00866	6.83e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_00867	3.85e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HFAPHBKH_00868	1.19e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HFAPHBKH_00869	6.59e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
HFAPHBKH_00870	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
HFAPHBKH_00871	6.9e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
HFAPHBKH_00872	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
HFAPHBKH_00873	8.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
HFAPHBKH_00874	3.82e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
HFAPHBKH_00875	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFAPHBKH_00876	6.88e-297	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
HFAPHBKH_00877	8.73e-09	yuzC	-	-	-	-	-	-	-
HFAPHBKH_00879	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
HFAPHBKH_00880	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
HFAPHBKH_00882	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_00883	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_00884	9.49e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
HFAPHBKH_00885	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
HFAPHBKH_00886	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFAPHBKH_00887	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFAPHBKH_00888	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFAPHBKH_00889	3.48e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFAPHBKH_00890	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HFAPHBKH_00891	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HFAPHBKH_00892	1.42e-21	-	-	-	-	-	-	-	-
HFAPHBKH_00893	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
HFAPHBKH_00894	1.71e-215	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFAPHBKH_00895	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
HFAPHBKH_00896	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_00897	9e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
HFAPHBKH_00898	1.88e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
HFAPHBKH_00899	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFAPHBKH_00900	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
HFAPHBKH_00901	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00902	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
HFAPHBKH_00903	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
HFAPHBKH_00905	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
HFAPHBKH_00906	8.36e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
HFAPHBKH_00907	4.32e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_00908	3.32e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HFAPHBKH_00909	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
HFAPHBKH_00910	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
HFAPHBKH_00911	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00912	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
HFAPHBKH_00913	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HFAPHBKH_00914	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
HFAPHBKH_00915	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
HFAPHBKH_00916	1.26e-287	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
HFAPHBKH_00917	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
HFAPHBKH_00919	4.22e-95	yugN	-	-	S	-	-	-	YugN-like family
HFAPHBKH_00920	8.37e-232	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
HFAPHBKH_00921	2.12e-70	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
HFAPHBKH_00922	2.16e-48	-	-	-	-	-	-	-	-
HFAPHBKH_00923	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
HFAPHBKH_00924	2.52e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFAPHBKH_00925	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFAPHBKH_00926	4.25e-94	yugU	-	-	S	-	-	-	Uncharacterised protein family UPF0047
HFAPHBKH_00927	1.44e-47	-	-	-	-	-	-	-	-
HFAPHBKH_00928	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
HFAPHBKH_00929	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00930	2.29e-295	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00931	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00932	8.35e-116	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00933	1.49e-184	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_00934	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
HFAPHBKH_00935	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFAPHBKH_00936	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HFAPHBKH_00937	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
HFAPHBKH_00938	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
HFAPHBKH_00939	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HFAPHBKH_00940	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
HFAPHBKH_00941	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HFAPHBKH_00943	3.95e-113	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
HFAPHBKH_00944	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
HFAPHBKH_00945	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFAPHBKH_00946	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
HFAPHBKH_00947	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
HFAPHBKH_00948	8.71e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HFAPHBKH_00949	5.83e-118	yuaB	-	-	-	-	-	-	-
HFAPHBKH_00950	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
HFAPHBKH_00951	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFAPHBKH_00952	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
HFAPHBKH_00953	3.92e-135	yuaD	-	-	-	-	-	-	-
HFAPHBKH_00954	2.81e-107	yuaE	-	-	S	-	-	-	DinB superfamily
HFAPHBKH_00955	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
HFAPHBKH_00956	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
HFAPHBKH_00957	5.71e-121	-	-	-	M	-	-	-	FR47-like protein
HFAPHBKH_00958	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
HFAPHBKH_00959	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
HFAPHBKH_00960	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFAPHBKH_00961	1.45e-198	yitS	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_00962	7.32e-49	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
HFAPHBKH_00964	2.75e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
HFAPHBKH_00965	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
HFAPHBKH_00966	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HFAPHBKH_00967	7.23e-92	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_00968	9.64e-94	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_00969	1.3e-198	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HFAPHBKH_00970	7.53e-97	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
HFAPHBKH_00971	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFAPHBKH_00972	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
HFAPHBKH_00973	9.94e-120	yisT	-	-	S	-	-	-	DinB family
HFAPHBKH_00974	5.32e-242	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
HFAPHBKH_00975	8.71e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
HFAPHBKH_00976	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_00977	1.01e-310	yisQ	-	-	V	-	-	-	Mate efflux family protein
HFAPHBKH_00978	3.44e-142	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
HFAPHBKH_00979	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFAPHBKH_00980	6.1e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
HFAPHBKH_00981	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFAPHBKH_00982	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
HFAPHBKH_00983	3.11e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HFAPHBKH_00984	1.09e-221	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
HFAPHBKH_00985	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HFAPHBKH_00986	1.82e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
HFAPHBKH_00987	1.76e-47	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
HFAPHBKH_00988	6.73e-92	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
HFAPHBKH_00989	6.07e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
HFAPHBKH_00990	3.92e-86	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
HFAPHBKH_00991	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
HFAPHBKH_00992	6.4e-65	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
HFAPHBKH_00993	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
HFAPHBKH_00994	5.45e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFAPHBKH_00995	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
HFAPHBKH_00996	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
HFAPHBKH_00997	9.3e-102	yhjR	-	-	S	-	-	-	Rubrerythrin
HFAPHBKH_00998	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
HFAPHBKH_00999	1.73e-270	-	-	-	EGP	-	-	-	Transmembrane secretion effector
HFAPHBKH_01000	1.38e-256	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
HFAPHBKH_01001	6.39e-119	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFAPHBKH_01002	3.4e-283	yhjG	-	-	CH	-	-	-	FAD binding domain
HFAPHBKH_01003	1.21e-30	yhjG	-	-	CH	-	-	-	FAD binding domain
HFAPHBKH_01004	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFAPHBKH_01005	4.87e-141	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
HFAPHBKH_01006	1.01e-75	yhjD	-	-	-	-	-	-	-
HFAPHBKH_01007	1.32e-35	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HFAPHBKH_01008	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFAPHBKH_01009	1.68e-55	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
HFAPHBKH_01010	8.19e-213	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFAPHBKH_01011	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
HFAPHBKH_01012	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
HFAPHBKH_01013	7.82e-204	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_01014	4.09e-238	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HFAPHBKH_01015	1.18e-120	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
HFAPHBKH_01016	8.74e-259	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
HFAPHBKH_01017	8.51e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
HFAPHBKH_01018	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HFAPHBKH_01019	2.11e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
HFAPHBKH_01020	1.13e-139	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
HFAPHBKH_01021	5.35e-221	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
HFAPHBKH_01022	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
HFAPHBKH_01023	7.28e-101	-	-	-	K	-	-	-	acetyltransferase
HFAPHBKH_01024	1.7e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFAPHBKH_01025	6.5e-306	yhfN	-	-	O	-	-	-	Peptidase M48
HFAPHBKH_01026	2.28e-84	yhfM	-	-	-	-	-	-	-
HFAPHBKH_01027	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
HFAPHBKH_01028	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
HFAPHBKH_01029	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
HFAPHBKH_01030	1.15e-180	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HFAPHBKH_01031	5.56e-288	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFAPHBKH_01032	1.53e-93	-	-	-	S	-	-	-	ASCH
HFAPHBKH_01033	1.27e-251	yhfE	-	-	G	-	-	-	peptidase M42
HFAPHBKH_01034	2.67e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
HFAPHBKH_01035	1.34e-126	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFAPHBKH_01036	2.47e-90	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFAPHBKH_01037	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
HFAPHBKH_01038	6.76e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_01039	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HFAPHBKH_01040	3.99e-230	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
HFAPHBKH_01041	6.13e-258	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HFAPHBKH_01042	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFAPHBKH_01043	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
HFAPHBKH_01044	1e-44	-	-	-	C	-	-	-	Rubrerythrin
HFAPHBKH_01045	1.82e-310	yhfA	-	-	C	-	-	-	membrane
HFAPHBKH_01046	1.27e-290	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HFAPHBKH_01047	2.89e-161	ecsC	-	-	S	-	-	-	EcsC protein family
HFAPHBKH_01048	2.55e-271	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFAPHBKH_01049	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
HFAPHBKH_01050	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HFAPHBKH_01051	7.5e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HFAPHBKH_01052	6.32e-104	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
HFAPHBKH_01053	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
HFAPHBKH_01054	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
HFAPHBKH_01055	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
HFAPHBKH_01056	5.71e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
HFAPHBKH_01057	4.7e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFAPHBKH_01058	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
HFAPHBKH_01059	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
HFAPHBKH_01060	0.0	yhaN	-	-	L	-	-	-	AAA domain
HFAPHBKH_01061	5.46e-300	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
HFAPHBKH_01062	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
HFAPHBKH_01063	4.57e-214	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_01064	5.43e-35	-	-	-	S	-	-	-	YhzD-like protein
HFAPHBKH_01065	3.41e-169	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
HFAPHBKH_01067	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HFAPHBKH_01068	1.85e-267	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
HFAPHBKH_01069	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
HFAPHBKH_01070	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
HFAPHBKH_01071	1.29e-261	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
HFAPHBKH_01072	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
HFAPHBKH_01073	4.16e-259	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
HFAPHBKH_01074	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HFAPHBKH_01075	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
HFAPHBKH_01076	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
HFAPHBKH_01077	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HFAPHBKH_01078	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
HFAPHBKH_01079	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFAPHBKH_01080	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFAPHBKH_01081	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFAPHBKH_01082	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HFAPHBKH_01083	2.6e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HFAPHBKH_01084	9.72e-192	nodB1	-	-	G	-	-	-	deacetylase
HFAPHBKH_01085	9.4e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HFAPHBKH_01086	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
HFAPHBKH_01087	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
HFAPHBKH_01088	9.03e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
HFAPHBKH_01089	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFAPHBKH_01090	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFAPHBKH_01091	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFAPHBKH_01092	3.62e-171	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFAPHBKH_01093	3.35e-92	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFAPHBKH_01094	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
HFAPHBKH_01095	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFAPHBKH_01096	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HFAPHBKH_01097	2.74e-243	yhdN	-	-	C	-	-	-	Aldo keto reductase
HFAPHBKH_01098	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_01099	6.13e-258	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
HFAPHBKH_01100	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
HFAPHBKH_01101	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFAPHBKH_01102	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HFAPHBKH_01103	1.01e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HFAPHBKH_01104	8.4e-315	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
HFAPHBKH_01105	3.72e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_01106	8.75e-260	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HFAPHBKH_01107	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_01108	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HFAPHBKH_01109	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HFAPHBKH_01110	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFAPHBKH_01111	3.17e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
HFAPHBKH_01112	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
HFAPHBKH_01114	2.87e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
HFAPHBKH_01115	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
HFAPHBKH_01116	3.17e-97	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFAPHBKH_01117	3.02e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFAPHBKH_01122	1.45e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_01123	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_01124	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01125	3.44e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01126	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HFAPHBKH_01127	9.43e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFAPHBKH_01128	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HFAPHBKH_01129	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
HFAPHBKH_01130	3.95e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HFAPHBKH_01131	6.81e-19	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
HFAPHBKH_01132	4.85e-119	-	-	-	-	-	-	-	-
HFAPHBKH_01133	5.82e-20	-	-	-	-	-	-	-	-
HFAPHBKH_01134	1.01e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
HFAPHBKH_01135	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFAPHBKH_01136	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HFAPHBKH_01138	2.06e-204	-	-	-	S	-	-	-	aspartate phosphatase
HFAPHBKH_01139	1.17e-18	-	-	-	S	-	-	-	aspartate phosphatase
HFAPHBKH_01140	2.97e-108	yycN	-	-	K	-	-	-	Acetyltransferase
HFAPHBKH_01141	3.24e-167	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HFAPHBKH_01142	7.64e-255	yycP	-	-	-	-	-	-	-
HFAPHBKH_01143	1.58e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HFAPHBKH_01145	8.21e-67	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFAPHBKH_01146	1.43e-54	-	-	-	S	-	-	-	LlaJI restriction endonuclease
HFAPHBKH_01147	6.97e-115	-	-	-	V	-	-	-	AAA domain (dynein-related subfamily)
HFAPHBKH_01148	3.24e-203	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HFAPHBKH_01149	3.2e-186	-	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	C-5 cytosine-specific DNA methylase
HFAPHBKH_01151	2.89e-105	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFAPHBKH_01152	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
HFAPHBKH_01153	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFAPHBKH_01154	9.5e-153	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFAPHBKH_01155	1.95e-159	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_01156	1.15e-37	-	2.7.1.199	-	G	ko:K02777,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFAPHBKH_01157	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFAPHBKH_01158	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
HFAPHBKH_01159	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
HFAPHBKH_01160	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFAPHBKH_01161	2.05e-295	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HFAPHBKH_01162	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
HFAPHBKH_01163	4.42e-164	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
HFAPHBKH_01164	1.16e-263	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
HFAPHBKH_01165	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
HFAPHBKH_01166	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
HFAPHBKH_01167	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
HFAPHBKH_01168	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFAPHBKH_01169	2.49e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_01170	1.12e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HFAPHBKH_01171	5.18e-251	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
HFAPHBKH_01172	1.46e-283	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
HFAPHBKH_01173	1.35e-97	yxaI	-	-	S	-	-	-	membrane protein domain
HFAPHBKH_01174	7.97e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
HFAPHBKH_01175	2.54e-43	yxaI	-	-	S	-	-	-	membrane protein domain
HFAPHBKH_01176	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFAPHBKH_01177	6.97e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFAPHBKH_01178	1.7e-23	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFAPHBKH_01180	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
HFAPHBKH_01181	2.4e-233	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_01182	2.22e-38	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_01183	4.47e-103	-	-	-	T	-	-	-	HPP family
HFAPHBKH_01184	2.23e-17	-	-	-	S	-	-	-	CGNR zinc finger
HFAPHBKH_01186	7.27e-55	-	-	-	-	-	-	-	-
HFAPHBKH_01187	3.52e-224	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
HFAPHBKH_01188	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFAPHBKH_01189	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFAPHBKH_01190	1.41e-199	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HFAPHBKH_01191	1.23e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HFAPHBKH_01192	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HFAPHBKH_01193	1.23e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HFAPHBKH_01194	1.21e-23	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HFAPHBKH_01195	2.8e-231	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
HFAPHBKH_01196	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HFAPHBKH_01197	4.4e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
HFAPHBKH_01198	2.29e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HFAPHBKH_01199	4.69e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HFAPHBKH_01200	2.8e-160	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_01201	9.03e-230	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_01202	6.59e-67	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_01203	5.08e-90	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_01204	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HFAPHBKH_01205	3.45e-76	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
HFAPHBKH_01206	1.27e-214	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFAPHBKH_01207	6.79e-91	-	-	-	-	-	-	-	-
HFAPHBKH_01208	7.57e-28	yxeD	-	-	-	-	-	-	-
HFAPHBKH_01209	5.99e-41	yxeE	-	-	-	-	-	-	-
HFAPHBKH_01212	3.29e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
HFAPHBKH_01213	1.64e-238	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
HFAPHBKH_01214	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFAPHBKH_01215	6.03e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFAPHBKH_01216	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HFAPHBKH_01217	6.05e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFAPHBKH_01218	1.13e-169	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_01219	2.89e-272	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
HFAPHBKH_01220	1.87e-316	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
HFAPHBKH_01221	1.49e-253	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
HFAPHBKH_01222	8.39e-194	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
HFAPHBKH_01223	7.06e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HFAPHBKH_01224	1.18e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFAPHBKH_01225	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFAPHBKH_01226	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
HFAPHBKH_01227	2.24e-204	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFAPHBKH_01228	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HFAPHBKH_01229	2.55e-306	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HFAPHBKH_01230	4.71e-108	-	-	-	L	-	-	-	HaeIII restriction endonuclease
HFAPHBKH_01231	1.65e-186	ddeI	2.1.1.37	-	L	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	DNA (cytosine-5-)-methyltransferase activity
HFAPHBKH_01232	8.25e-58	-	-	-	L	ko:K07458	-	ko00000,ko01000,ko03400	May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HFAPHBKH_01234	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
HFAPHBKH_01235	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
HFAPHBKH_01236	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
HFAPHBKH_01237	5.35e-102	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
HFAPHBKH_01238	1.56e-53	-	-	-	-	-	-	-	-
HFAPHBKH_01239	1.99e-82	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFAPHBKH_01240	3.07e-216	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFAPHBKH_01241	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
HFAPHBKH_01242	1.52e-155	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
HFAPHBKH_01243	1.36e-160	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_01244	5.69e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_01246	1.46e-264	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
HFAPHBKH_01247	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
HFAPHBKH_01248	4.39e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
HFAPHBKH_01249	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFAPHBKH_01250	1.58e-130	yfmS	-	-	NT	-	-	-	chemotaxis protein
HFAPHBKH_01251	1.09e-18	yfmS	-	-	NT	-	-	-	chemotaxis protein
HFAPHBKH_01252	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFAPHBKH_01253	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
HFAPHBKH_01254	2.05e-165	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
HFAPHBKH_01255	7.24e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_01256	2.73e-242	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HFAPHBKH_01257	3.71e-281	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
HFAPHBKH_01258	1.1e-228	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
HFAPHBKH_01259	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
HFAPHBKH_01260	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
HFAPHBKH_01261	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HFAPHBKH_01262	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HFAPHBKH_01263	1.94e-248	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
HFAPHBKH_01264	5.94e-131	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
HFAPHBKH_01265	1.3e-38	yetM	-	-	CH	-	-	-	FAD binding domain
HFAPHBKH_01266	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
HFAPHBKH_01267	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
HFAPHBKH_01268	7.83e-183	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFAPHBKH_01269	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFAPHBKH_01270	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
HFAPHBKH_01271	3.66e-157	yetF	-	-	S	-	-	-	membrane
HFAPHBKH_01272	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HFAPHBKH_01273	1.3e-207	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFAPHBKH_01274	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HFAPHBKH_01275	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFAPHBKH_01276	1.71e-209	yetA	-	-	-	-	-	-	-
HFAPHBKH_01277	5.02e-234	yetA	-	-	-	-	-	-	-
HFAPHBKH_01278	2.25e-127	yetA	-	-	-	-	-	-	-
HFAPHBKH_01279	2.97e-193	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HFAPHBKH_01280	8.37e-153	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HFAPHBKH_01281	2.73e-80	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
HFAPHBKH_01282	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFAPHBKH_01283	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HFAPHBKH_01284	3.4e-116	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
HFAPHBKH_01285	1.25e-21	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFAPHBKH_01286	1.17e-217	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFAPHBKH_01287	7.99e-312	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFAPHBKH_01288	2.41e-199	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
HFAPHBKH_01289	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_01290	2.56e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
HFAPHBKH_01292	4.15e-131	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
HFAPHBKH_01293	1.04e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
HFAPHBKH_01294	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
HFAPHBKH_01295	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
HFAPHBKH_01296	1.23e-195	yesF	-	-	GM	-	-	-	NAD(P)H-binding
HFAPHBKH_01297	4.95e-107	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
HFAPHBKH_01298	7.28e-132	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_01300	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
HFAPHBKH_01302	4.97e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HFAPHBKH_01303	1.23e-14	-	-	-	S	-	-	-	Pfam:DUF1311
HFAPHBKH_01304	5.68e-126	-	-	-	L	-	-	-	endonuclease activity
HFAPHBKH_01306	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_01307	1.41e-72	-	-	-	S	-	-	-	Protein of unknown function, DUF600
HFAPHBKH_01309	0.0	-	-	-	K	-	-	-	SIR2-like domain
HFAPHBKH_01310	1.14e-27	-	-	-	-	-	-	-	-
HFAPHBKH_01311	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFAPHBKH_01312	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HFAPHBKH_01313	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFAPHBKH_01314	6.97e-189	yerO	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_01315	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFAPHBKH_01316	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFAPHBKH_01317	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFAPHBKH_01318	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFAPHBKH_01319	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
HFAPHBKH_01320	3.49e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
HFAPHBKH_01321	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFAPHBKH_01322	6.3e-105	yfiV	-	-	K	-	-	-	transcriptional
HFAPHBKH_01323	7.84e-145	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
HFAPHBKH_01324	2.31e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
HFAPHBKH_01325	1.25e-255	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
HFAPHBKH_01326	4.68e-138	yfiR	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_01327	2.99e-249	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HFAPHBKH_01328	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HFAPHBKH_01329	1.28e-126	padR	-	-	K	-	-	-	transcriptional
HFAPHBKH_01330	7.56e-85	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_01331	1.23e-255	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
HFAPHBKH_01332	1.15e-261	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFAPHBKH_01333	5.93e-201	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_01334	2.78e-110	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HFAPHBKH_01335	2.15e-09	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
HFAPHBKH_01336	4.16e-251	baeS	-	-	T	-	-	-	Histidine kinase
HFAPHBKH_01338	4.36e-249	-	-	-	S	-	-	-	Oxidoreductase
HFAPHBKH_01339	2.46e-32	-	-	-	S	-	-	-	Oxidoreductase
HFAPHBKH_01340	5.47e-234	-	-	-	G	-	-	-	Xylose isomerase
HFAPHBKH_01341	0.0	yfiG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_01342	1.28e-228	-	-	-	K	ko:K02099	-	ko00000,ko03000	AraC-like ligand binding domain
HFAPHBKH_01343	7.28e-209	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
HFAPHBKH_01344	2.01e-84	yfiD3	-	-	S	-	-	-	DoxX
HFAPHBKH_01345	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFAPHBKH_01346	5.1e-96	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFAPHBKH_01347	1.52e-204	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
HFAPHBKH_01348	0.0	yobO	-	-	M	-	-	-	COG5434 Endopolygalacturonase
HFAPHBKH_01349	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_01350	8.69e-181	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
HFAPHBKH_01351	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HFAPHBKH_01352	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
HFAPHBKH_01353	1.94e-270	yfjB	-	-	-	-	-	-	-
HFAPHBKH_01354	1.02e-184	yfjC	-	-	-	-	-	-	-
HFAPHBKH_01355	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
HFAPHBKH_01356	1e-105	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
HFAPHBKH_01357	6.86e-73	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
HFAPHBKH_01358	3.9e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
HFAPHBKH_01359	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
HFAPHBKH_01360	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFAPHBKH_01361	3.01e-258	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFAPHBKH_01362	4.56e-243	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFAPHBKH_01363	1.12e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFAPHBKH_01365	3.74e-108	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
HFAPHBKH_01366	9.53e-241	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFAPHBKH_01367	4.32e-59	-	-	-	S	-	-	-	YfzA-like protein
HFAPHBKH_01368	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFAPHBKH_01369	5.57e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFAPHBKH_01370	1.24e-233	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
HFAPHBKH_01371	7.99e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HFAPHBKH_01372	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
HFAPHBKH_01373	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
HFAPHBKH_01374	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
HFAPHBKH_01375	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HFAPHBKH_01376	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
HFAPHBKH_01377	2.53e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
HFAPHBKH_01378	8.1e-236	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFAPHBKH_01379	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HFAPHBKH_01380	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HFAPHBKH_01381	2.27e-220	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFAPHBKH_01382	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFAPHBKH_01383	9.73e-180	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
HFAPHBKH_01384	2.93e-45	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_01385	5.15e-161	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_01386	1.53e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HFAPHBKH_01387	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_01388	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_01389	7.48e-239	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
HFAPHBKH_01390	1.29e-182	yccK	-	-	C	-	-	-	Aldo keto reductase
HFAPHBKH_01391	2.9e-28	yccK	-	-	C	-	-	-	Aldo keto reductase
HFAPHBKH_01392	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFAPHBKH_01393	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFAPHBKH_01394	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
HFAPHBKH_01395	6.18e-213	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
HFAPHBKH_01396	2.49e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
HFAPHBKH_01397	4.32e-78	-	-	-	S	-	-	-	RDD family
HFAPHBKH_01398	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HFAPHBKH_01399	8.37e-258	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HFAPHBKH_01400	4.42e-130	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
HFAPHBKH_01401	4.75e-307	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HFAPHBKH_01402	4.66e-257	ycbU	-	-	E	-	-	-	Selenocysteine lyase
HFAPHBKH_01403	3.43e-154	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HFAPHBKH_01404	3.09e-159	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HFAPHBKH_01405	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HFAPHBKH_01406	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
HFAPHBKH_01407	6.36e-173	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
HFAPHBKH_01408	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
HFAPHBKH_01409	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HFAPHBKH_01410	1.73e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
HFAPHBKH_01411	5.55e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_01412	4.37e-214	ycbM	-	-	T	-	-	-	Histidine kinase
HFAPHBKH_01413	5.28e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_01414	4.05e-215	eamA1	-	-	EG	-	-	-	spore germination
HFAPHBKH_01415	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
HFAPHBKH_01416	3.51e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
HFAPHBKH_01417	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HFAPHBKH_01418	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
HFAPHBKH_01419	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HFAPHBKH_01420	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_01421	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFAPHBKH_01422	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
HFAPHBKH_01423	5.76e-216	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
HFAPHBKH_01424	5.88e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_01425	1.77e-237	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HFAPHBKH_01426	0.0	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HFAPHBKH_01427	1.83e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
HFAPHBKH_01428	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFAPHBKH_01429	1.25e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFAPHBKH_01431	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HFAPHBKH_01432	1.01e-172	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFAPHBKH_01433	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_01434	6.04e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFAPHBKH_01435	1.16e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
HFAPHBKH_01436	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_01437	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
HFAPHBKH_01438	2.25e-59	ybfN	-	-	-	-	-	-	-
HFAPHBKH_01439	6.15e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HFAPHBKH_01440	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
HFAPHBKH_01441	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFAPHBKH_01442	1.31e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFAPHBKH_01444	3.97e-227	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
HFAPHBKH_01445	1.54e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFAPHBKH_01446	2.61e-73	-	-	-	-	-	-	-	-
HFAPHBKH_01447	1.93e-122	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
HFAPHBKH_01448	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
HFAPHBKH_01449	3.63e-43	-	-	-	K	-	-	-	sigma factor activity
HFAPHBKH_01450	7.39e-188	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
HFAPHBKH_01451	1.06e-207	ybfH	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_01452	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
HFAPHBKH_01455	6.21e-57	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_01456	5.4e-184	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_01457	8.65e-202	ybfA	-	-	K	-	-	-	FR47-like protein
HFAPHBKH_01458	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
HFAPHBKH_01459	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
HFAPHBKH_01460	2.09e-212	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
HFAPHBKH_01461	0.0	ybeC	-	-	E	-	-	-	amino acid
HFAPHBKH_01462	1.28e-37	ybyB	-	-	-	-	-	-	-
HFAPHBKH_01463	2.46e-310	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
HFAPHBKH_01464	1.24e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
HFAPHBKH_01465	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
HFAPHBKH_01466	2.23e-50	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
HFAPHBKH_01467	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_01468	7.06e-271	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
HFAPHBKH_01469	1.49e-192	ybdN	-	-	-	-	-	-	-
HFAPHBKH_01470	1.96e-178	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
HFAPHBKH_01472	2.78e-219	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
HFAPHBKH_01473	1.55e-65	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
HFAPHBKH_01474	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HFAPHBKH_01475	4.6e-63	-	-	-	-	-	-	-	-
HFAPHBKH_01477	1.63e-121	ybcF	-	-	P	-	-	-	carbonic anhydrase
HFAPHBKH_01478	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
HFAPHBKH_01479	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HFAPHBKH_01480	1.29e-129	adaB	2.1.1.63	-	L	ko:K00567,ko:K10778,ko:K13531	-	ko00000,ko01000,ko03000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFAPHBKH_01481	6.2e-155	adaA	-	-	K	ko:K13530	-	ko00000,ko01000,ko03000,ko03400	Transcriptional regulator
HFAPHBKH_01482	4.2e-61	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFAPHBKH_01483	2.05e-231	ydaD_3	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
HFAPHBKH_01484	1.97e-53	-	-	-	-	-	-	-	-
HFAPHBKH_01485	1.68e-274	fdh	1.1.1.1, 1.1.1.284	-	E	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFAPHBKH_01486	1.01e-306	-	-	-	-	-	-	-	-
HFAPHBKH_01487	0.0	-	-	-	L	-	-	-	Tn7-like transposition protein D
HFAPHBKH_01488	0.0	-	-	-	L	-	-	-	Bacterial TniB protein
HFAPHBKH_01489	0.0	-	-	-	L	-	-	-	Mu transposase, C-terminal
HFAPHBKH_01490	1.55e-159	tnsA	-	-	L	-	-	-	TnsA endonuclease N terminal
HFAPHBKH_01491	5.87e-54	alkA	3.2.2.21	-	L	ko:K01247,ko:K13529	ko03410,map03410	ko00000,ko00001,ko01000,ko03000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HFAPHBKH_01492	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFAPHBKH_01493	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFAPHBKH_01494	5.59e-288	ybbR	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01495	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFAPHBKH_01496	2.73e-152	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HFAPHBKH_01497	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_01503	2.43e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
HFAPHBKH_01504	3.13e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
HFAPHBKH_01505	5.5e-209	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HFAPHBKH_01506	3.51e-190	ybbH	-	-	K	-	-	-	transcriptional
HFAPHBKH_01507	1.04e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_01508	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
HFAPHBKH_01509	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
HFAPHBKH_01510	2.33e-302	ybbC	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01511	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
HFAPHBKH_01512	2.54e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
HFAPHBKH_01513	5.81e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_01514	1.43e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_01515	7.76e-182	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
HFAPHBKH_01516	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
HFAPHBKH_01518	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
HFAPHBKH_01520	1e-89	-	-	-	S	-	-	-	Phage terminase, small subunit
HFAPHBKH_01521	8.79e-12	-	-	-	-	-	-	-	-
HFAPHBKH_01522	5.53e-84	-	-	-	S	-	-	-	HNH endonuclease
HFAPHBKH_01529	5.89e-58	-	-	-	L	-	-	-	Phage integrase family
HFAPHBKH_01530	5.52e-31	-	-	-	M	-	-	-	ArpU family transcriptional regulator
HFAPHBKH_01535	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFAPHBKH_01536	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFAPHBKH_01537	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
HFAPHBKH_01538	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
HFAPHBKH_01539	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HFAPHBKH_01540	1.62e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFAPHBKH_01541	1.96e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HFAPHBKH_01542	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
HFAPHBKH_01543	3.57e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
HFAPHBKH_01544	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
HFAPHBKH_01545	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
HFAPHBKH_01546	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFAPHBKH_01547	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
HFAPHBKH_01548	1.36e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFAPHBKH_01549	3.56e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
HFAPHBKH_01550	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
HFAPHBKH_01551	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HFAPHBKH_01552	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HFAPHBKH_01553	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
HFAPHBKH_01554	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
HFAPHBKH_01555	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_01556	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_01557	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFAPHBKH_01558	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
HFAPHBKH_01559	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
HFAPHBKH_01560	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFAPHBKH_01561	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFAPHBKH_01562	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFAPHBKH_01563	4.77e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFAPHBKH_01564	1.36e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HFAPHBKH_01565	2.16e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
HFAPHBKH_01566	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
HFAPHBKH_01567	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
HFAPHBKH_01568	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
HFAPHBKH_01569	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HFAPHBKH_01570	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFAPHBKH_01571	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
HFAPHBKH_01572	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFAPHBKH_01573	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFAPHBKH_01574	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
HFAPHBKH_01575	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFAPHBKH_01576	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
HFAPHBKH_01577	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
HFAPHBKH_01578	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
HFAPHBKH_01579	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
HFAPHBKH_01580	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFAPHBKH_01581	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFAPHBKH_01582	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
HFAPHBKH_01583	1.14e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HFAPHBKH_01584	4.74e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
HFAPHBKH_01585	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFAPHBKH_01586	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFAPHBKH_01587	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
HFAPHBKH_01588	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFAPHBKH_01589	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
HFAPHBKH_01590	6.91e-101	ylxL	-	-	-	-	-	-	-
HFAPHBKH_01591	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_01592	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HFAPHBKH_01593	1.45e-143	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HFAPHBKH_01594	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
HFAPHBKH_01595	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
HFAPHBKH_01596	4.27e-251	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HFAPHBKH_01597	3.14e-200	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
HFAPHBKH_01598	8.03e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
HFAPHBKH_01599	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HFAPHBKH_01600	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HFAPHBKH_01601	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
HFAPHBKH_01602	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
HFAPHBKH_01603	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
HFAPHBKH_01604	1.3e-135	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
HFAPHBKH_01605	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
HFAPHBKH_01606	1.38e-253	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HFAPHBKH_01607	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HFAPHBKH_01608	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
HFAPHBKH_01609	1.42e-175	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
HFAPHBKH_01610	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
HFAPHBKH_01611	1.36e-306	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
HFAPHBKH_01612	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
HFAPHBKH_01613	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
HFAPHBKH_01614	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HFAPHBKH_01615	4.51e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
HFAPHBKH_01616	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HFAPHBKH_01617	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
HFAPHBKH_01618	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
HFAPHBKH_01619	7.54e-99	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
HFAPHBKH_01620	1.33e-82	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HFAPHBKH_01621	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HFAPHBKH_01622	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HFAPHBKH_01623	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HFAPHBKH_01624	6.51e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
HFAPHBKH_01625	5.45e-314	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HFAPHBKH_01626	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFAPHBKH_01627	2.66e-217	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
HFAPHBKH_01628	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HFAPHBKH_01629	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HFAPHBKH_01630	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
HFAPHBKH_01631	0.0	ylqG	-	-	-	-	-	-	-
HFAPHBKH_01632	1.18e-174	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFAPHBKH_01633	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFAPHBKH_01634	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFAPHBKH_01635	1.98e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
HFAPHBKH_01636	7.5e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFAPHBKH_01637	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
HFAPHBKH_01638	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
HFAPHBKH_01639	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
HFAPHBKH_01640	1.13e-307	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFAPHBKH_01641	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFAPHBKH_01642	1.67e-114	-	-	-	-	-	-	-	-
HFAPHBKH_01643	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFAPHBKH_01644	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
HFAPHBKH_01645	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFAPHBKH_01646	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFAPHBKH_01647	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
HFAPHBKH_01648	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
HFAPHBKH_01649	8.33e-230	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFAPHBKH_01650	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HFAPHBKH_01651	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFAPHBKH_01652	2.4e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HFAPHBKH_01653	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
HFAPHBKH_01654	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
HFAPHBKH_01655	3.01e-77	yloU	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01656	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
HFAPHBKH_01657	1.15e-156	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
HFAPHBKH_01658	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
HFAPHBKH_01659	7.9e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFAPHBKH_01660	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFAPHBKH_01661	8.34e-179	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
HFAPHBKH_01662	2.16e-263	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HFAPHBKH_01663	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFAPHBKH_01664	2.03e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFAPHBKH_01665	8.3e-110	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFAPHBKH_01666	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFAPHBKH_01667	4.21e-285	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFAPHBKH_01668	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFAPHBKH_01669	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
HFAPHBKH_01670	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
HFAPHBKH_01671	6.91e-201	yloC	-	-	S	-	-	-	stress-induced protein
HFAPHBKH_01672	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
HFAPHBKH_01673	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
HFAPHBKH_01674	9.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
HFAPHBKH_01675	2.06e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
HFAPHBKH_01676	6.89e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
HFAPHBKH_01677	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
HFAPHBKH_01678	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
HFAPHBKH_01679	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
HFAPHBKH_01680	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
HFAPHBKH_01681	3e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFAPHBKH_01682	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFAPHBKH_01683	4.97e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFAPHBKH_01684	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HFAPHBKH_01685	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
HFAPHBKH_01686	1.86e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFAPHBKH_01687	0.0	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFAPHBKH_01688	5.99e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
HFAPHBKH_01689	8.02e-291	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
HFAPHBKH_01690	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFAPHBKH_01691	2.38e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
HFAPHBKH_01692	3.85e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFAPHBKH_01693	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HFAPHBKH_01694	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFAPHBKH_01695	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
HFAPHBKH_01696	2.03e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
HFAPHBKH_01697	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
HFAPHBKH_01698	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFAPHBKH_01699	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFAPHBKH_01700	7.53e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
HFAPHBKH_01701	3.58e-51	ylmC	-	-	S	-	-	-	sporulation protein
HFAPHBKH_01702	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
HFAPHBKH_01703	6.37e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HFAPHBKH_01704	6.57e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_01705	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_01706	3.49e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HFAPHBKH_01708	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
HFAPHBKH_01709	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFAPHBKH_01710	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFAPHBKH_01711	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
HFAPHBKH_01712	8.67e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01713	3.45e-146	ylxW	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01714	1.37e-177	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFAPHBKH_01715	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
HFAPHBKH_01716	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFAPHBKH_01717	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFAPHBKH_01718	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFAPHBKH_01719	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFAPHBKH_01720	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFAPHBKH_01721	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
HFAPHBKH_01722	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFAPHBKH_01723	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
HFAPHBKH_01724	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFAPHBKH_01725	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
HFAPHBKH_01726	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HFAPHBKH_01727	3.22e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFAPHBKH_01728	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
HFAPHBKH_01729	1.35e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HFAPHBKH_01730	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
HFAPHBKH_01731	6.94e-117	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
HFAPHBKH_01733	1.67e-291	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
HFAPHBKH_01734	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
HFAPHBKH_01735	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFAPHBKH_01736	3.41e-183	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
HFAPHBKH_01737	7.77e-283	yabE	-	-	T	-	-	-	protein conserved in bacteria
HFAPHBKH_01738	2.46e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFAPHBKH_01739	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFAPHBKH_01740	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
HFAPHBKH_01741	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_01742	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
HFAPHBKH_01743	9.53e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFAPHBKH_01744	3.82e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
HFAPHBKH_01745	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
HFAPHBKH_01746	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HFAPHBKH_01747	2.47e-307	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFAPHBKH_01748	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFAPHBKH_01749	2.77e-125	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HFAPHBKH_01750	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFAPHBKH_01751	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
HFAPHBKH_01752	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFAPHBKH_01753	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
HFAPHBKH_01754	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFAPHBKH_01755	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HFAPHBKH_01756	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HFAPHBKH_01757	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
HFAPHBKH_01758	2.58e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
HFAPHBKH_01759	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
HFAPHBKH_01760	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
HFAPHBKH_01763	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
HFAPHBKH_01764	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFAPHBKH_01765	6.63e-234	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
HFAPHBKH_01766	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFAPHBKH_01767	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
HFAPHBKH_01768	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFAPHBKH_01769	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HFAPHBKH_01770	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFAPHBKH_01771	2.41e-204	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
HFAPHBKH_01772	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFAPHBKH_01773	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFAPHBKH_01774	2.44e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
HFAPHBKH_01775	8.89e-214	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
HFAPHBKH_01776	7.82e-204	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFAPHBKH_01777	1.09e-79	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFAPHBKH_01778	4.56e-115	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFAPHBKH_01779	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
HFAPHBKH_01780	1.59e-243	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFAPHBKH_01781	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
HFAPHBKH_01782	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
HFAPHBKH_01783	2.17e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
HFAPHBKH_01785	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFAPHBKH_01786	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
HFAPHBKH_01787	2.7e-68	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
HFAPHBKH_01788	8.79e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HFAPHBKH_01790	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
HFAPHBKH_01791	6.11e-106	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
HFAPHBKH_01792	2.68e-28	yjfB	-	-	S	-	-	-	Putative motility protein
HFAPHBKH_01793	2.45e-214	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
HFAPHBKH_01794	1.38e-59	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
HFAPHBKH_01795	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
HFAPHBKH_01796	5.56e-290	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HFAPHBKH_01797	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HFAPHBKH_01798	5.25e-113	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HFAPHBKH_01801	4.85e-143	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
HFAPHBKH_01803	4.06e-287	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFAPHBKH_01804	1.76e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HFAPHBKH_01805	1.11e-41	-	-	-	-	-	-	-	-
HFAPHBKH_01806	4.81e-184	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HFAPHBKH_01807	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
HFAPHBKH_01808	1.55e-172	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
HFAPHBKH_01809	2.36e-220	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
HFAPHBKH_01810	2.18e-112	yjlB	-	-	S	-	-	-	Cupin domain
HFAPHBKH_01811	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HFAPHBKH_01812	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFAPHBKH_01813	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
HFAPHBKH_01814	1.86e-164	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HFAPHBKH_01815	1.23e-129	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
HFAPHBKH_01816	4.2e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
HFAPHBKH_01817	2.09e-242	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
HFAPHBKH_01818	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
HFAPHBKH_01819	1.83e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_01820	4.58e-288	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
HFAPHBKH_01821	8.11e-237	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
HFAPHBKH_01822	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
HFAPHBKH_01823	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
HFAPHBKH_01824	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFAPHBKH_01825	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
HFAPHBKH_01826	6.08e-314	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
HFAPHBKH_01827	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_01829	1.09e-34	-	-	-	S	-	-	-	YCII-related domain
HFAPHBKH_01830	3.09e-217	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFAPHBKH_01831	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
HFAPHBKH_01832	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
HFAPHBKH_01833	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
HFAPHBKH_01834	1.79e-143	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
HFAPHBKH_01835	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
HFAPHBKH_01837	2.07e-200	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
HFAPHBKH_01838	8.72e-152	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
HFAPHBKH_01843	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HFAPHBKH_01844	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
HFAPHBKH_01845	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
HFAPHBKH_01846	0.0	yqbA	-	-	S	-	-	-	portal protein
HFAPHBKH_01847	4.02e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
HFAPHBKH_01848	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
HFAPHBKH_01849	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
HFAPHBKH_01850	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
HFAPHBKH_01851	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFAPHBKH_01852	2.87e-101	xkdJ	-	-	-	-	-	-	-
HFAPHBKH_01853	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
HFAPHBKH_01854	6.01e-99	xkdM	-	-	S	-	-	-	Phage tail tube protein
HFAPHBKH_01855	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
HFAPHBKH_01856	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
HFAPHBKH_01857	1.73e-151	xkdP	-	-	S	-	-	-	Lysin motif
HFAPHBKH_01858	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
HFAPHBKH_01859	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
HFAPHBKH_01860	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
HFAPHBKH_01861	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HFAPHBKH_01862	3.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
HFAPHBKH_01863	4.43e-56	-	-	-	-	-	-	-	-
HFAPHBKH_01864	0.0	-	-	-	-	-	-	-	-
HFAPHBKH_01865	2.7e-68	xkdW	-	-	S	-	-	-	XkdW protein
HFAPHBKH_01866	6.35e-31	xkdX	-	-	-	-	-	-	-
HFAPHBKH_01867	9.79e-195	xepA	-	-	-	-	-	-	-
HFAPHBKH_01868	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
HFAPHBKH_01869	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
HFAPHBKH_01870	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HFAPHBKH_01871	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
HFAPHBKH_01872	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
HFAPHBKH_01873	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
HFAPHBKH_01874	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
HFAPHBKH_01875	1.81e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
HFAPHBKH_01876	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HFAPHBKH_01877	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HFAPHBKH_01878	1.28e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFAPHBKH_01880	2.73e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFAPHBKH_01881	4.95e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
HFAPHBKH_01882	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
HFAPHBKH_01883	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFAPHBKH_01884	1.23e-223	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFAPHBKH_01885	7.78e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_01886	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFAPHBKH_01888	5.33e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
HFAPHBKH_01889	3.21e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
HFAPHBKH_01890	4.03e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HFAPHBKH_01891	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_01892	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
HFAPHBKH_01893	9.79e-102	ykgA	-	-	E	-	-	-	Amidinotransferase
HFAPHBKH_01894	5.42e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
HFAPHBKH_01895	4.21e-286	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFAPHBKH_01896	9.93e-15	-	-	-	-	-	-	-	-
HFAPHBKH_01897	1.32e-165	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_01898	2.51e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
HFAPHBKH_01899	2.43e-126	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFAPHBKH_01900	2.99e-71	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HFAPHBKH_01901	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
HFAPHBKH_01902	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HFAPHBKH_01903	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFAPHBKH_01904	4.59e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFAPHBKH_01905	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HFAPHBKH_01906	1.66e-96	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
HFAPHBKH_01907	4.72e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
HFAPHBKH_01908	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
HFAPHBKH_01909	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HFAPHBKH_01910	1.49e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFAPHBKH_01911	3.27e-192	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFAPHBKH_01912	1.63e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFAPHBKH_01913	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HFAPHBKH_01914	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFAPHBKH_01915	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFAPHBKH_01916	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
HFAPHBKH_01917	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_01918	4.23e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
HFAPHBKH_01919	9.27e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
HFAPHBKH_01920	3.34e-267	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
HFAPHBKH_01921	9.38e-95	ytwI	-	-	S	-	-	-	membrane
HFAPHBKH_01922	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
HFAPHBKH_01923	3.16e-80	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
HFAPHBKH_01924	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
HFAPHBKH_01925	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HFAPHBKH_01926	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HFAPHBKH_01927	5.1e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFAPHBKH_01928	1.21e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HFAPHBKH_01929	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
HFAPHBKH_01930	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
HFAPHBKH_01931	5.12e-112	ytrI	-	-	-	-	-	-	-
HFAPHBKH_01932	1.15e-39	-	-	-	-	-	-	-	-
HFAPHBKH_01933	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
HFAPHBKH_01934	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
HFAPHBKH_01935	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
HFAPHBKH_01936	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
HFAPHBKH_01937	3.28e-181	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_01939	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
HFAPHBKH_01940	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFAPHBKH_01941	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
HFAPHBKH_01942	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFAPHBKH_01943	6.26e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
HFAPHBKH_01944	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HFAPHBKH_01945	1.06e-94	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
HFAPHBKH_01946	5.03e-150	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
HFAPHBKH_01947	2.36e-111	yteJ	-	-	S	-	-	-	RDD family
HFAPHBKH_01948	4.62e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
HFAPHBKH_01949	1.69e-189	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFAPHBKH_01950	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
HFAPHBKH_01951	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HFAPHBKH_01952	2.12e-40	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
HFAPHBKH_01953	8.89e-289	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFAPHBKH_01954	2.74e-266	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HFAPHBKH_01955	8.23e-305	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFAPHBKH_01956	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFAPHBKH_01957	3.73e-198	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HFAPHBKH_01958	9.83e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_01959	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
HFAPHBKH_01960	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
HFAPHBKH_01961	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFAPHBKH_01963	4.36e-302	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFAPHBKH_01964	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HFAPHBKH_01965	3.46e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HFAPHBKH_01966	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
HFAPHBKH_01967	1.79e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
HFAPHBKH_01968	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HFAPHBKH_01969	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HFAPHBKH_01970	1.7e-234	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
HFAPHBKH_01971	3.11e-249	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HFAPHBKH_01972	1.57e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
HFAPHBKH_01973	2.15e-22	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
HFAPHBKH_01974	7.61e-26	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFAPHBKH_01975	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
HFAPHBKH_01976	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
HFAPHBKH_01977	1.78e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFAPHBKH_01978	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
HFAPHBKH_01979	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
HFAPHBKH_01980	7.02e-103	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
HFAPHBKH_01981	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
HFAPHBKH_01982	6.75e-67	ytzB	-	-	S	-	-	-	small secreted protein
HFAPHBKH_01983	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
HFAPHBKH_01984	3.18e-192	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFAPHBKH_01985	7.53e-157	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFAPHBKH_01986	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
HFAPHBKH_01987	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
HFAPHBKH_01988	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
HFAPHBKH_01989	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
HFAPHBKH_01990	4.92e-212	ytlQ	-	-	-	-	-	-	-
HFAPHBKH_01991	2.13e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HFAPHBKH_01992	3e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
HFAPHBKH_01993	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
HFAPHBKH_01994	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFAPHBKH_01995	2.89e-254	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
HFAPHBKH_01996	4.65e-167	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFAPHBKH_01997	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
HFAPHBKH_01998	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
HFAPHBKH_01999	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
HFAPHBKH_02000	7.1e-198	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
HFAPHBKH_02001	7.81e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFAPHBKH_02002	1.18e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
HFAPHBKH_02003	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFAPHBKH_02004	1.58e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFAPHBKH_02005	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFAPHBKH_02006	3.77e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFAPHBKH_02007	6.38e-195	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
HFAPHBKH_02008	8.11e-222	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_02009	5.76e-212	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HFAPHBKH_02010	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
HFAPHBKH_02011	1.18e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HFAPHBKH_02012	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
HFAPHBKH_02013	1.49e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFAPHBKH_02014	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
HFAPHBKH_02015	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02017	5.45e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
HFAPHBKH_02018	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HFAPHBKH_02019	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
HFAPHBKH_02020	4.5e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
HFAPHBKH_02021	3.93e-183	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFAPHBKH_02022	2.51e-32	yqzJ	-	-	-	-	-	-	-
HFAPHBKH_02023	1.84e-299	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFAPHBKH_02024	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFAPHBKH_02025	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFAPHBKH_02026	2.2e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFAPHBKH_02027	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
HFAPHBKH_02028	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HFAPHBKH_02029	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HFAPHBKH_02030	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HFAPHBKH_02031	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFAPHBKH_02032	1.56e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFAPHBKH_02033	2.81e-184	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_02034	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
HFAPHBKH_02035	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
HFAPHBKH_02036	5.23e-93	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFAPHBKH_02038	1.68e-288	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
HFAPHBKH_02040	4.7e-303	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFAPHBKH_02041	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
HFAPHBKH_02042	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
HFAPHBKH_02043	1.52e-76	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
HFAPHBKH_02044	3.23e-248	yqkA	-	-	K	-	-	-	GrpB protein
HFAPHBKH_02045	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
HFAPHBKH_02046	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
HFAPHBKH_02047	4.61e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HFAPHBKH_02048	8.04e-27	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
HFAPHBKH_02049	2.09e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
HFAPHBKH_02050	6.19e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
HFAPHBKH_02051	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
HFAPHBKH_02052	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
HFAPHBKH_02053	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02054	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
HFAPHBKH_02055	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
HFAPHBKH_02056	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
HFAPHBKH_02057	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HFAPHBKH_02058	1.47e-41	yqkK	-	-	-	-	-	-	-
HFAPHBKH_02059	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HFAPHBKH_02060	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
HFAPHBKH_02061	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
HFAPHBKH_02062	1.31e-212	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
HFAPHBKH_02063	2.28e-292	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFAPHBKH_02064	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HFAPHBKH_02065	3.37e-271	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFAPHBKH_02066	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
HFAPHBKH_02067	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HFAPHBKH_02068	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_02069	1.15e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
HFAPHBKH_02070	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
HFAPHBKH_02071	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HFAPHBKH_02072	6.02e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HFAPHBKH_02073	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HFAPHBKH_02074	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HFAPHBKH_02075	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
HFAPHBKH_02076	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFAPHBKH_02077	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
HFAPHBKH_02078	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFAPHBKH_02079	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFAPHBKH_02082	6.41e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
HFAPHBKH_02083	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
HFAPHBKH_02084	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
HFAPHBKH_02085	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFAPHBKH_02087	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFAPHBKH_02088	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
HFAPHBKH_02089	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HFAPHBKH_02090	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
HFAPHBKH_02091	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
HFAPHBKH_02092	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
HFAPHBKH_02093	9.28e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
HFAPHBKH_02094	2.45e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HFAPHBKH_02095	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFAPHBKH_02096	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFAPHBKH_02097	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFAPHBKH_02099	5.61e-73	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HFAPHBKH_02100	1.14e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
HFAPHBKH_02101	2.55e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
HFAPHBKH_02102	2.36e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFAPHBKH_02103	6.48e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
HFAPHBKH_02104	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFAPHBKH_02105	9.57e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
HFAPHBKH_02106	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
HFAPHBKH_02107	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFAPHBKH_02108	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFAPHBKH_02109	1.83e-79	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
HFAPHBKH_02110	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
HFAPHBKH_02111	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFAPHBKH_02112	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFAPHBKH_02113	5.36e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFAPHBKH_02114	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFAPHBKH_02115	1.82e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFAPHBKH_02116	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFAPHBKH_02117	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
HFAPHBKH_02118	2.92e-113	ywmA	-	-	-	-	-	-	-
HFAPHBKH_02119	4.54e-45	ywzB	-	-	S	-	-	-	membrane
HFAPHBKH_02120	6.59e-172	ywmB	-	-	S	-	-	-	TATA-box binding
HFAPHBKH_02121	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFAPHBKH_02122	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
HFAPHBKH_02123	6.09e-49	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFAPHBKH_02124	8.56e-96	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFAPHBKH_02125	3.4e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
HFAPHBKH_02127	9.06e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HFAPHBKH_02128	2.65e-246	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HFAPHBKH_02129	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_02130	3.48e-109	ywmF	-	-	S	-	-	-	Peptidase M50
HFAPHBKH_02131	2.15e-19	csbD	-	-	K	-	-	-	CsbD-like
HFAPHBKH_02132	0.000282	-	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
HFAPHBKH_02133	6.75e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
HFAPHBKH_02134	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
HFAPHBKH_02135	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HFAPHBKH_02136	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02137	6.73e-19	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HFAPHBKH_02138	1.42e-112	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
HFAPHBKH_02139	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HFAPHBKH_02140	1.28e-179	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
HFAPHBKH_02141	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFAPHBKH_02142	1.05e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
HFAPHBKH_02143	6.7e-234	-	-	-	M	-	-	-	NeuB family
HFAPHBKH_02144	5.63e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
HFAPHBKH_02145	2.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
HFAPHBKH_02146	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HFAPHBKH_02147	9.05e-93	ywnJ	-	-	S	-	-	-	VanZ like family
HFAPHBKH_02148	1.72e-134	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
HFAPHBKH_02149	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
HFAPHBKH_02150	3.76e-287	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
HFAPHBKH_02151	7.16e-101	-	-	-	-	-	-	-	-
HFAPHBKH_02152	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
HFAPHBKH_02153	3.63e-305	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
HFAPHBKH_02154	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
HFAPHBKH_02155	3.25e-309	ywoF	-	-	P	-	-	-	Right handed beta helix region
HFAPHBKH_02156	3.21e-268	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_02157	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
HFAPHBKH_02158	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
HFAPHBKH_02159	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
HFAPHBKH_02160	4.16e-171	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HFAPHBKH_02161	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
HFAPHBKH_02162	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
HFAPHBKH_02163	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFAPHBKH_02164	7.66e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFAPHBKH_02165	4.66e-186	ywpD	-	-	T	-	-	-	Histidine kinase
HFAPHBKH_02166	3.81e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
HFAPHBKH_02167	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
HFAPHBKH_02168	2.79e-40	ywpG	-	-	-	-	-	-	-
HFAPHBKH_02169	4.23e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
HFAPHBKH_02170	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
HFAPHBKH_02171	1.45e-199	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HFAPHBKH_02172	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
HFAPHBKH_02173	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
HFAPHBKH_02174	3.6e-25	-	-	-	-	-	-	-	-
HFAPHBKH_02175	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
HFAPHBKH_02176	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
HFAPHBKH_02177	1.75e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
HFAPHBKH_02178	6.34e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFAPHBKH_02179	1.3e-38	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HFAPHBKH_02180	1.45e-108	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
HFAPHBKH_02182	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
HFAPHBKH_02183	3.15e-265	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_02184	2.5e-26	-	-	-	-	-	-	-	-
HFAPHBKH_02185	1.3e-23	-	-	-	-	-	-	-	-
HFAPHBKH_02186	4.93e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
HFAPHBKH_02187	9.77e-48	-	-	-	S	ko:K11904,ko:K21493	ko03070,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko02048	protein secretion by the type VII secretion system
HFAPHBKH_02189	2.88e-147	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HFAPHBKH_02190	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02191	1.44e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
HFAPHBKH_02193	0.0	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HFAPHBKH_02194	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
HFAPHBKH_02195	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HFAPHBKH_02196	1.09e-307	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
HFAPHBKH_02197	0.0	-	-	-	O	-	-	-	Peptidase family M48
HFAPHBKH_02199	1.77e-197	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
HFAPHBKH_02200	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_02201	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
HFAPHBKH_02202	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HFAPHBKH_02203	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HFAPHBKH_02204	1.74e-250	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFAPHBKH_02205	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
HFAPHBKH_02206	1.25e-242	-	-	-	T	-	-	-	Signal transduction histidine kinase
HFAPHBKH_02207	2.69e-148	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
HFAPHBKH_02208	1.06e-296	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
HFAPHBKH_02210	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
HFAPHBKH_02211	5.01e-276	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HFAPHBKH_02212	2.21e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
HFAPHBKH_02213	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HFAPHBKH_02214	1.69e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HFAPHBKH_02215	7.21e-60	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFAPHBKH_02216	9.99e-66	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFAPHBKH_02217	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
HFAPHBKH_02218	2.42e-201	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
HFAPHBKH_02219	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFAPHBKH_02220	9.87e-132	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
HFAPHBKH_02221	6.3e-61	yxiS	-	-	-	-	-	-	-
HFAPHBKH_02222	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HFAPHBKH_02223	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HFAPHBKH_02224	7.21e-183	bglS	-	-	M	-	-	-	licheninase activity
HFAPHBKH_02225	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HFAPHBKH_02226	2.16e-142	-	-	-	-	-	-	-	-
HFAPHBKH_02227	1.8e-290	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
HFAPHBKH_02228	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HFAPHBKH_02229	8.65e-275	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFAPHBKH_02232	1.94e-56	yxiJ	-	-	S	-	-	-	YxiJ-like protein
HFAPHBKH_02235	1.86e-40	-	-	-	-	-	-	-	-
HFAPHBKH_02236	4.99e-121	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
HFAPHBKH_02237	1.85e-177	-	-	-	-	-	-	-	-
HFAPHBKH_02238	8.76e-99	yxiG	-	-	-	-	-	-	-
HFAPHBKH_02239	1.12e-82	-	-	-	-	-	-	-	-
HFAPHBKH_02240	5.25e-111	-	-	-	-	-	-	-	-
HFAPHBKH_02241	1.09e-94	yxxG	-	-	-	-	-	-	-
HFAPHBKH_02242	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
HFAPHBKH_02243	3.57e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
HFAPHBKH_02244	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFAPHBKH_02245	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
HFAPHBKH_02246	4.48e-161	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HFAPHBKH_02248	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
HFAPHBKH_02249	6.27e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02250	2.63e-241	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
HFAPHBKH_02251	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
HFAPHBKH_02252	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
HFAPHBKH_02253	7.12e-293	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
HFAPHBKH_02254	6.15e-95	-	-	-	K	-	-	-	helix_turn_helix ASNC type
HFAPHBKH_02255	9.43e-297	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
HFAPHBKH_02256	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
HFAPHBKH_02257	3.62e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFAPHBKH_02258	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
HFAPHBKH_02259	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFAPHBKH_02260	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFAPHBKH_02261	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFAPHBKH_02262	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFAPHBKH_02263	5.86e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
HFAPHBKH_02264	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFAPHBKH_02265	2.69e-277	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFAPHBKH_02266	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFAPHBKH_02267	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
HFAPHBKH_02268	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
HFAPHBKH_02270	9.69e-164	yebC	-	-	M	-	-	-	Membrane
HFAPHBKH_02271	4.65e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
HFAPHBKH_02272	1.97e-315	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
HFAPHBKH_02273	6.3e-111	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_02274	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
HFAPHBKH_02275	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
HFAPHBKH_02276	2.63e-284	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HFAPHBKH_02277	3.25e-225	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
HFAPHBKH_02278	7.15e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFAPHBKH_02279	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_02280	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
HFAPHBKH_02281	7.26e-204	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
HFAPHBKH_02282	1.46e-201	-	-	-	I	-	-	-	Alpha/beta hydrolase family
HFAPHBKH_02283	9.99e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
HFAPHBKH_02285	2.83e-237	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFAPHBKH_02286	2.31e-178	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
HFAPHBKH_02287	1.26e-268	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
HFAPHBKH_02288	3.69e-260	-	-	-	S	-	-	-	Acetyltransferase
HFAPHBKH_02289	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
HFAPHBKH_02290	1.12e-83	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HFAPHBKH_02291	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
HFAPHBKH_02292	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFAPHBKH_02293	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HFAPHBKH_02294	5.11e-49	ydaS	-	-	S	-	-	-	membrane
HFAPHBKH_02295	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
HFAPHBKH_02296	6.49e-290	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFAPHBKH_02297	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
HFAPHBKH_02298	1.98e-157	ywcC	-	-	K	-	-	-	transcriptional regulator
HFAPHBKH_02300	1.23e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
HFAPHBKH_02301	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFAPHBKH_02302	1.26e-144	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
HFAPHBKH_02303	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
HFAPHBKH_02304	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
HFAPHBKH_02305	0.0	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
HFAPHBKH_02306	1e-145	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFAPHBKH_02307	5.39e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFAPHBKH_02308	1.28e-201	ywbI	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02309	4.47e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HFAPHBKH_02310	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
HFAPHBKH_02311	7.14e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
HFAPHBKH_02312	1.05e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
HFAPHBKH_02313	1.28e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
HFAPHBKH_02314	8.1e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
HFAPHBKH_02315	2.61e-163	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
HFAPHBKH_02316	1.81e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFAPHBKH_02317	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFAPHBKH_02318	4.43e-307	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_02319	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HFAPHBKH_02320	6.17e-241	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFAPHBKH_02321	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
HFAPHBKH_02322	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFAPHBKH_02323	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
HFAPHBKH_02324	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFAPHBKH_02325	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
HFAPHBKH_02326	7.7e-169	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
HFAPHBKH_02327	5.2e-187	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
HFAPHBKH_02328	2.66e-138	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFAPHBKH_02329	3.77e-139	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFAPHBKH_02330	5.38e-12	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
HFAPHBKH_02331	8.4e-42	yrzR	-	-	-	-	-	-	-
HFAPHBKH_02332	2.79e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02333	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFAPHBKH_02334	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
HFAPHBKH_02335	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFAPHBKH_02336	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HFAPHBKH_02337	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_02338	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HFAPHBKH_02339	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HFAPHBKH_02340	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HFAPHBKH_02341	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
HFAPHBKH_02343	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
HFAPHBKH_02346	4.26e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase family
HFAPHBKH_02347	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
HFAPHBKH_02348	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HFAPHBKH_02349	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFAPHBKH_02350	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
HFAPHBKH_02351	4.51e-237	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HFAPHBKH_02352	8.02e-84	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
HFAPHBKH_02353	2.1e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
HFAPHBKH_02354	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HFAPHBKH_02355	2.17e-38	-	-	-	-	-	-	-	-
HFAPHBKH_02357	1.78e-73	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_02358	4.9e-36	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_02359	8.96e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_02360	1.28e-98	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFAPHBKH_02361	5.54e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HFAPHBKH_02362	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
HFAPHBKH_02363	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFAPHBKH_02364	5.76e-70	-	-	-	S	-	-	-	DoxX-like family
HFAPHBKH_02365	8.04e-111	yycN	-	-	K	-	-	-	Acetyltransferase
HFAPHBKH_02366	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
HFAPHBKH_02367	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_02368	5.94e-118	-	-	-	S	-	-	-	DinB family
HFAPHBKH_02369	2.06e-104	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFAPHBKH_02370	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
HFAPHBKH_02371	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
HFAPHBKH_02372	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
HFAPHBKH_02373	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
HFAPHBKH_02374	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
HFAPHBKH_02375	5.42e-95	ywiB	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02376	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
HFAPHBKH_02377	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
HFAPHBKH_02379	5.02e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
HFAPHBKH_02380	1.81e-292	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
HFAPHBKH_02381	3.84e-273	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
HFAPHBKH_02382	1.17e-315	-	-	-	L	-	-	-	Peptidase, M16
HFAPHBKH_02384	1.31e-303	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
HFAPHBKH_02385	1.57e-96	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HFAPHBKH_02386	1.72e-156	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
HFAPHBKH_02387	3.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFAPHBKH_02389	2.76e-65	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
HFAPHBKH_02390	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
HFAPHBKH_02391	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HFAPHBKH_02392	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFAPHBKH_02393	2.1e-64	-	-	-	-	-	-	-	-
HFAPHBKH_02394	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
HFAPHBKH_02395	5.45e-153	ywhC	-	-	S	-	-	-	Peptidase family M50
HFAPHBKH_02396	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
HFAPHBKH_02397	1.76e-94	ywhA	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02398	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFAPHBKH_02400	1.54e-306	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
HFAPHBKH_02401	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02402	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
HFAPHBKH_02403	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
HFAPHBKH_02404	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
HFAPHBKH_02405	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
HFAPHBKH_02406	5.88e-200	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
HFAPHBKH_02407	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HFAPHBKH_02408	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_02409	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
HFAPHBKH_02410	3.43e-187	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
HFAPHBKH_02411	7.94e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
HFAPHBKH_02412	9e-297	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
HFAPHBKH_02413	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
HFAPHBKH_02414	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HFAPHBKH_02415	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_02416	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HFAPHBKH_02417	1.71e-144	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HFAPHBKH_02418	1.09e-274	ywfA	-	-	EGP	-	-	-	-transporter
HFAPHBKH_02419	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
HFAPHBKH_02420	1.09e-42	rocB	-	-	E	-	-	-	arginine degradation protein
HFAPHBKH_02421	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
HFAPHBKH_02422	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
HFAPHBKH_02423	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFAPHBKH_02424	3.7e-101	-	-	-	-	-	-	-	-
HFAPHBKH_02425	3.73e-113	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
HFAPHBKH_02426	1.92e-203	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFAPHBKH_02427	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFAPHBKH_02428	7.45e-178	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HFAPHBKH_02429	6.41e-237	spsG	-	-	M	-	-	-	Spore Coat
HFAPHBKH_02430	4.64e-169	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
HFAPHBKH_02431	1.95e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
HFAPHBKH_02432	4.22e-210	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
HFAPHBKH_02433	6.44e-285	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
HFAPHBKH_02434	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
HFAPHBKH_02435	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
HFAPHBKH_02436	3.62e-112	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HFAPHBKH_02437	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
HFAPHBKH_02438	1.53e-302	ywdJ	-	-	F	-	-	-	Xanthine uracil
HFAPHBKH_02439	2.18e-63	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
HFAPHBKH_02440	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFAPHBKH_02441	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFAPHBKH_02442	5.46e-191	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
HFAPHBKH_02443	5.2e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
HFAPHBKH_02444	6.19e-39	ywdA	-	-	-	-	-	-	-
HFAPHBKH_02445	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
HFAPHBKH_02446	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_02447	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
HFAPHBKH_02448	3.69e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
HFAPHBKH_02450	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
HFAPHBKH_02452	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
HFAPHBKH_02453	1.73e-13	-	-	-	-	-	-	-	-
HFAPHBKH_02454	3.96e-84	-	-	-	O	-	-	-	Papain family cysteine protease
HFAPHBKH_02456	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
HFAPHBKH_02457	3.82e-37	-	-	-	-	-	-	-	-
HFAPHBKH_02459	5.68e-58	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFAPHBKH_02461	1.75e-43	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
HFAPHBKH_02462	1.67e-125	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFAPHBKH_02463	5.98e-72	ypuD	-	-	-	-	-	-	-
HFAPHBKH_02464	2.07e-260	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFAPHBKH_02465	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
HFAPHBKH_02466	1.04e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HFAPHBKH_02467	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFAPHBKH_02468	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFAPHBKH_02469	1.4e-117	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
HFAPHBKH_02470	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFAPHBKH_02471	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFAPHBKH_02472	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
HFAPHBKH_02473	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFAPHBKH_02474	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
HFAPHBKH_02475	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
HFAPHBKH_02476	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFAPHBKH_02477	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HFAPHBKH_02478	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
HFAPHBKH_02479	1.56e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HFAPHBKH_02480	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_02481	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_02482	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_02483	1.15e-244	rsiX	-	-	-	-	-	-	-
HFAPHBKH_02484	1.32e-171	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HFAPHBKH_02485	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFAPHBKH_02486	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFAPHBKH_02487	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
HFAPHBKH_02488	1.28e-254	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
HFAPHBKH_02489	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFAPHBKH_02490	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
HFAPHBKH_02491	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
HFAPHBKH_02492	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
HFAPHBKH_02493	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HFAPHBKH_02494	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HFAPHBKH_02495	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
HFAPHBKH_02496	2.51e-222	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
HFAPHBKH_02497	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
HFAPHBKH_02498	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
HFAPHBKH_02499	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
HFAPHBKH_02500	1.09e-142	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
HFAPHBKH_02501	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
HFAPHBKH_02502	2.36e-145	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
HFAPHBKH_02503	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
HFAPHBKH_02504	4.66e-235	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFAPHBKH_02505	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
HFAPHBKH_02506	2.73e-134	yphA	-	-	-	-	-	-	-
HFAPHBKH_02507	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
HFAPHBKH_02508	2.06e-38	ypzH	-	-	-	-	-	-	-
HFAPHBKH_02509	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
HFAPHBKH_02510	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
HFAPHBKH_02511	1.43e-26	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
HFAPHBKH_02512	8.71e-176	yphF	-	-	-	-	-	-	-
HFAPHBKH_02513	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HFAPHBKH_02514	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFAPHBKH_02515	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
HFAPHBKH_02516	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HFAPHBKH_02517	8.72e-178	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HFAPHBKH_02518	1.1e-168	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFAPHBKH_02519	5.81e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
HFAPHBKH_02520	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HFAPHBKH_02521	1.5e-182	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
HFAPHBKH_02522	1.44e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFAPHBKH_02523	3.86e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HFAPHBKH_02524	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HFAPHBKH_02525	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFAPHBKH_02526	6.08e-230	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFAPHBKH_02527	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
HFAPHBKH_02528	2.6e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
HFAPHBKH_02529	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HFAPHBKH_02530	3.14e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HFAPHBKH_02531	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HFAPHBKH_02532	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
HFAPHBKH_02533	9.49e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFAPHBKH_02534	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
HFAPHBKH_02535	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
HFAPHBKH_02536	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
HFAPHBKH_02537	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
HFAPHBKH_02538	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
HFAPHBKH_02539	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
HFAPHBKH_02540	1.15e-125	ypjA	-	-	S	-	-	-	membrane
HFAPHBKH_02541	6.56e-181	ypjB	-	-	S	-	-	-	sporulation protein
HFAPHBKH_02542	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
HFAPHBKH_02543	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
HFAPHBKH_02544	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFAPHBKH_02545	1.03e-92	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
HFAPHBKH_02546	2.69e-166	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
HFAPHBKH_02547	1.41e-266	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
HFAPHBKH_02548	1.06e-278	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFAPHBKH_02549	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFAPHBKH_02550	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HFAPHBKH_02551	1.57e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HFAPHBKH_02552	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HFAPHBKH_02553	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
HFAPHBKH_02554	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
HFAPHBKH_02555	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02556	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
HFAPHBKH_02557	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
HFAPHBKH_02558	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
HFAPHBKH_02559	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFAPHBKH_02560	1.43e-121	ypoC	-	-	-	-	-	-	-
HFAPHBKH_02561	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
HFAPHBKH_02562	1.3e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFAPHBKH_02563	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
HFAPHBKH_02566	1.42e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
HFAPHBKH_02567	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
HFAPHBKH_02568	8.72e-68	yppG	-	-	S	-	-	-	YppG-like protein
HFAPHBKH_02569	1.76e-94	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFAPHBKH_02570	6.1e-109	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
HFAPHBKH_02571	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HFAPHBKH_02572	1.98e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
HFAPHBKH_02573	3.99e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
HFAPHBKH_02574	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFAPHBKH_02575	3.32e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
HFAPHBKH_02577	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
HFAPHBKH_02578	3.12e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_02579	7.26e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HFAPHBKH_02580	7.8e-238	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
HFAPHBKH_02581	4.02e-237	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
HFAPHBKH_02582	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
HFAPHBKH_02583	2.36e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HFAPHBKH_02584	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HFAPHBKH_02585	9.13e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFAPHBKH_02586	8.61e-292	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HFAPHBKH_02587	1.49e-201	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HFAPHBKH_02588	4.08e-41	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
HFAPHBKH_02589	1.36e-112	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
HFAPHBKH_02590	0.0	ypbR	-	-	S	-	-	-	Dynamin family
HFAPHBKH_02591	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
HFAPHBKH_02592	7.57e-12	-	-	-	-	-	-	-	-
HFAPHBKH_02593	1.31e-212	ypcP	-	-	L	-	-	-	5'3' exonuclease
HFAPHBKH_02594	5.23e-05	-	-	-	-	ko:K06429	-	ko00000	-
HFAPHBKH_02595	1.27e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
HFAPHBKH_02596	6.59e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HFAPHBKH_02597	1.56e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
HFAPHBKH_02598	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
HFAPHBKH_02599	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
HFAPHBKH_02600	1.17e-22	degR	-	-	-	-	-	-	-
HFAPHBKH_02601	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HFAPHBKH_02602	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HFAPHBKH_02603	1.01e-223	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFAPHBKH_02604	5.2e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
HFAPHBKH_02605	2.42e-140	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
HFAPHBKH_02606	4.68e-203	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
HFAPHBKH_02607	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
HFAPHBKH_02608	2.78e-98	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
HFAPHBKH_02609	2.31e-182	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
HFAPHBKH_02610	2.01e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
HFAPHBKH_02611	1.8e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HFAPHBKH_02612	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFAPHBKH_02613	4.7e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HFAPHBKH_02614	6.6e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
HFAPHBKH_02615	5.47e-234	yplP	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02616	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFAPHBKH_02617	2.12e-53	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
HFAPHBKH_02618	1.24e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HFAPHBKH_02619	2.78e-175	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
HFAPHBKH_02620	5.59e-128	ypmS	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02621	8.69e-40	ypmT	-	-	S	-	-	-	Uncharacterized ympT
HFAPHBKH_02622	2.35e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
HFAPHBKH_02623	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
HFAPHBKH_02624	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFAPHBKH_02625	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
HFAPHBKH_02626	1.36e-156	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
HFAPHBKH_02627	1.34e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
HFAPHBKH_02628	4.45e-226	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
HFAPHBKH_02629	3.62e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
HFAPHBKH_02630	3.04e-59	cgeC	-	-	-	ko:K06321	-	ko00000	-
HFAPHBKH_02631	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
HFAPHBKH_02632	1.97e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
HFAPHBKH_02634	3.28e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFAPHBKH_02636	9.44e-153	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HFAPHBKH_02637	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
HFAPHBKH_02638	1.24e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
HFAPHBKH_02639	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
HFAPHBKH_02640	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
HFAPHBKH_02641	3.49e-48	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
HFAPHBKH_02642	7.44e-159	yodN	-	-	-	-	-	-	-
HFAPHBKH_02644	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
HFAPHBKH_02645	5.26e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
HFAPHBKH_02646	3.35e-71	yodL	-	-	S	-	-	-	YodL-like
HFAPHBKH_02647	2.08e-12	-	-	-	-	-	-	-	-
HFAPHBKH_02648	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
HFAPHBKH_02649	1.33e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
HFAPHBKH_02650	4.86e-41	yodI	-	-	-	-	-	-	-
HFAPHBKH_02651	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
HFAPHBKH_02652	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
HFAPHBKH_02653	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFAPHBKH_02654	2.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
HFAPHBKH_02655	5.38e-220	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
HFAPHBKH_02656	3.61e-144	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
HFAPHBKH_02657	6.44e-139	yodC	-	-	C	-	-	-	nitroreductase
HFAPHBKH_02658	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
HFAPHBKH_02659	3.97e-84	iolK	-	-	S	-	-	-	tautomerase
HFAPHBKH_02660	7.01e-96	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HFAPHBKH_02661	1.26e-168	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
HFAPHBKH_02662	5.59e-14	-	-	-	-	-	-	-	-
HFAPHBKH_02663	7.43e-107	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
HFAPHBKH_02664	1.64e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
HFAPHBKH_02665	1.85e-58	-	-	-	-	-	-	-	-
HFAPHBKH_02666	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
HFAPHBKH_02667	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
HFAPHBKH_02668	1.01e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HFAPHBKH_02669	5.06e-314	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
HFAPHBKH_02671	3.69e-142	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFAPHBKH_02672	3.79e-292	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
HFAPHBKH_02673	1.07e-266	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HFAPHBKH_02674	3.62e-142	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HFAPHBKH_02675	8.98e-206	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
HFAPHBKH_02676	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
HFAPHBKH_02677	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HFAPHBKH_02678	3.02e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HFAPHBKH_02679	5.48e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
HFAPHBKH_02680	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HFAPHBKH_02681	1.3e-206	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
HFAPHBKH_02682	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
HFAPHBKH_02683	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
HFAPHBKH_02684	1.91e-42	yozC	-	-	-	-	-	-	-
HFAPHBKH_02685	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
HFAPHBKH_02686	1.83e-49	yocN	-	-	-	-	-	-	-
HFAPHBKH_02687	2.94e-55	yozN	-	-	-	-	-	-	-
HFAPHBKH_02688	1.5e-111	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
HFAPHBKH_02689	6.54e-40	-	-	-	-	-	-	-	-
HFAPHBKH_02690	4.29e-70	yocL	-	-	-	-	-	-	-
HFAPHBKH_02691	1.42e-107	yocK	-	-	T	-	-	-	general stress protein
HFAPHBKH_02692	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFAPHBKH_02693	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFAPHBKH_02694	1.7e-167	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
HFAPHBKH_02696	1.11e-133	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_02697	4.99e-252	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_02698	1.14e-257	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
HFAPHBKH_02699	2.62e-238	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
HFAPHBKH_02700	1.08e-121	yocC	-	-	-	-	-	-	-
HFAPHBKH_02701	8.68e-67	-	-	-	-	-	-	-	-
HFAPHBKH_02702	1.14e-86	-	-	-	-	-	-	-	-
HFAPHBKH_02703	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
HFAPHBKH_02704	6.28e-114	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HFAPHBKH_02705	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
HFAPHBKH_02706	2.58e-121	yobW	-	-	-	-	-	-	-
HFAPHBKH_02707	2.76e-220	yobV	-	-	K	-	-	-	WYL domain
HFAPHBKH_02708	8.64e-112	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
HFAPHBKH_02709	4.49e-168	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFAPHBKH_02710	7.27e-126	yobS	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02711	1.98e-178	-	-	-	J	-	-	-	FR47-like protein
HFAPHBKH_02712	1.18e-171	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
HFAPHBKH_02713	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
HFAPHBKH_02714	4.84e-55	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
HFAPHBKH_02715	8.27e-278	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
HFAPHBKH_02716	1.14e-131	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
HFAPHBKH_02717	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HFAPHBKH_02718	1.35e-111	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HFAPHBKH_02719	7.57e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
HFAPHBKH_02720	4.05e-128	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
HFAPHBKH_02721	1.06e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_02723	8.09e-53	-	-	-	-	-	-	-	-
HFAPHBKH_02724	6.76e-87	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HFAPHBKH_02725	2.02e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
HFAPHBKH_02726	2.47e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
HFAPHBKH_02727	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HFAPHBKH_02728	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
HFAPHBKH_02729	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFAPHBKH_02730	1.53e-35	-	-	-	-	-	-	-	-
HFAPHBKH_02731	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HFAPHBKH_02732	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
HFAPHBKH_02733	1.44e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HFAPHBKH_02734	2.14e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
HFAPHBKH_02735	4.13e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
HFAPHBKH_02736	6.27e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HFAPHBKH_02737	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
HFAPHBKH_02738	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HFAPHBKH_02739	4.77e-116	ysxD	-	-	-	-	-	-	-
HFAPHBKH_02740	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
HFAPHBKH_02741	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HFAPHBKH_02742	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
HFAPHBKH_02743	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFAPHBKH_02744	2.54e-286	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFAPHBKH_02745	4.53e-239	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
HFAPHBKH_02746	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFAPHBKH_02747	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HFAPHBKH_02748	2.04e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HFAPHBKH_02749	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFAPHBKH_02750	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HFAPHBKH_02751	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HFAPHBKH_02752	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
HFAPHBKH_02754	1.38e-84	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
HFAPHBKH_02755	3.36e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02757	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
HFAPHBKH_02758	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFAPHBKH_02759	4.12e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HFAPHBKH_02760	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
HFAPHBKH_02761	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFAPHBKH_02762	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFAPHBKH_02763	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_02764	1.26e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
HFAPHBKH_02765	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HFAPHBKH_02766	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
HFAPHBKH_02767	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
HFAPHBKH_02768	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
HFAPHBKH_02769	4.62e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
HFAPHBKH_02770	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFAPHBKH_02771	1.87e-68	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
HFAPHBKH_02772	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
HFAPHBKH_02774	8.29e-226	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
HFAPHBKH_02775	1.74e-177	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
HFAPHBKH_02776	5.17e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
HFAPHBKH_02777	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_02778	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFAPHBKH_02779	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
HFAPHBKH_02780	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFAPHBKH_02781	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
HFAPHBKH_02782	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
HFAPHBKH_02783	2.45e-53	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HFAPHBKH_02784	1.47e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFAPHBKH_02785	1.8e-87	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
HFAPHBKH_02786	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HFAPHBKH_02787	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
HFAPHBKH_02793	7.75e-09	-	-	-	S	-	-	-	peptidoglycan catabolic process
HFAPHBKH_02794	2.45e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
HFAPHBKH_02795	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFAPHBKH_02796	1.87e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
HFAPHBKH_02797	3.77e-52	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
HFAPHBKH_02798	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HFAPHBKH_02799	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
HFAPHBKH_02800	1.5e-204	yybS	-	-	S	-	-	-	membrane
HFAPHBKH_02802	2.89e-110	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
HFAPHBKH_02803	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02804	2.83e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
HFAPHBKH_02805	3.19e-90	-	-	-	-	-	-	-	-
HFAPHBKH_02807	1.01e-307	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_02808	2.61e-122	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
HFAPHBKH_02809	2.91e-183	-	-	-	-	-	-	-	-
HFAPHBKH_02810	2.39e-85	-	-	-	S	-	-	-	SnoaL-like domain
HFAPHBKH_02811	2.81e-162	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
HFAPHBKH_02812	6.02e-127	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_02813	2.04e-88	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HFAPHBKH_02814	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
HFAPHBKH_02815	4.18e-90	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_02816	8.63e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
HFAPHBKH_02817	4.7e-120	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
HFAPHBKH_02818	1.5e-85	-	-	-	S	-	-	-	YjbR
HFAPHBKH_02819	1.57e-128	yyaP	-	-	H	-	-	-	RibD C-terminal domain
HFAPHBKH_02820	3.27e-257	tetL	-	-	EGP	ko:K08168	-	ko00000,ko00002,ko01504,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_02821	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
HFAPHBKH_02822	2.1e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFAPHBKH_02823	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
HFAPHBKH_02824	1.33e-129	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
HFAPHBKH_02825	7.2e-90	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFAPHBKH_02826	1.44e-228	ccpB	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_02827	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
HFAPHBKH_02828	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFAPHBKH_02829	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFAPHBKH_02830	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
HFAPHBKH_02831	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFAPHBKH_02832	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFAPHBKH_02833	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_02834	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
HFAPHBKH_02835	1.3e-144	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
HFAPHBKH_02836	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
HFAPHBKH_02837	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
HFAPHBKH_02838	3.77e-97	-	-	-	S	-	-	-	Bacterial PH domain
HFAPHBKH_02839	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HFAPHBKH_02840	1.01e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HFAPHBKH_02841	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFAPHBKH_02842	9.06e-317	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFAPHBKH_02843	1.83e-141	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
HFAPHBKH_02844	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFAPHBKH_02845	1.64e-70	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFAPHBKH_02846	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFAPHBKH_02847	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFAPHBKH_02848	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
HFAPHBKH_02849	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFAPHBKH_02850	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
HFAPHBKH_02851	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFAPHBKH_02852	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFAPHBKH_02853	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
HFAPHBKH_02854	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
HFAPHBKH_02855	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
HFAPHBKH_02856	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HFAPHBKH_02857	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HFAPHBKH_02858	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
HFAPHBKH_02859	1.45e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
HFAPHBKH_02860	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
HFAPHBKH_02861	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFAPHBKH_02862	1.51e-182	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFAPHBKH_02863	1.6e-177	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFAPHBKH_02864	1.1e-196	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFAPHBKH_02865	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFAPHBKH_02866	1.01e-75	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
HFAPHBKH_02867	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFAPHBKH_02868	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFAPHBKH_02869	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFAPHBKH_02870	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
HFAPHBKH_02871	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFAPHBKH_02872	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HFAPHBKH_02873	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFAPHBKH_02874	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFAPHBKH_02875	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
HFAPHBKH_02876	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
HFAPHBKH_02877	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFAPHBKH_02878	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFAPHBKH_02879	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFAPHBKH_02880	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFAPHBKH_02881	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFAPHBKH_02882	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFAPHBKH_02883	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFAPHBKH_02884	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFAPHBKH_02885	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFAPHBKH_02886	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
HFAPHBKH_02887	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFAPHBKH_02888	6.89e-151	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFAPHBKH_02889	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFAPHBKH_02890	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFAPHBKH_02891	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFAPHBKH_02892	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFAPHBKH_02893	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
HFAPHBKH_02894	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFAPHBKH_02895	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
HFAPHBKH_02896	7.13e-228	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
HFAPHBKH_02897	2.01e-287	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFAPHBKH_02898	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFAPHBKH_02899	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFAPHBKH_02900	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFAPHBKH_02901	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
HFAPHBKH_02902	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFAPHBKH_02903	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFAPHBKH_02904	2.43e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
HFAPHBKH_02905	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFAPHBKH_02906	1.64e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFAPHBKH_02907	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFAPHBKH_02908	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFAPHBKH_02909	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
HFAPHBKH_02910	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFAPHBKH_02911	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
HFAPHBKH_02912	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
HFAPHBKH_02913	1.43e-172	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFAPHBKH_02914	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFAPHBKH_02915	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
HFAPHBKH_02916	5.46e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
HFAPHBKH_02917	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFAPHBKH_02918	6.35e-113	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HFAPHBKH_02919	2.13e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HFAPHBKH_02920	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
HFAPHBKH_02921	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HFAPHBKH_02922	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFAPHBKH_02923	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
HFAPHBKH_02924	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HFAPHBKH_02925	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
HFAPHBKH_02926	7.17e-99	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
HFAPHBKH_02927	2.45e-83	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_02929	9.39e-63	yhcM	-	-	-	-	-	-	-
HFAPHBKH_02930	3.11e-106	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFAPHBKH_02931	1.01e-217	yhcP	-	-	-	-	-	-	-
HFAPHBKH_02932	1.06e-140	yhcQ	-	-	M	-	-	-	Spore coat protein
HFAPHBKH_02933	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFAPHBKH_02934	2.08e-133	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
HFAPHBKH_02935	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
HFAPHBKH_02936	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
HFAPHBKH_02937	7.16e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
HFAPHBKH_02938	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
HFAPHBKH_02939	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HFAPHBKH_02940	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFAPHBKH_02941	1.08e-134	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HFAPHBKH_02942	6.65e-195	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
HFAPHBKH_02943	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFAPHBKH_02944	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HFAPHBKH_02945	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
HFAPHBKH_02946	2.56e-270	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_02947	1.15e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_02948	2.7e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
HFAPHBKH_02949	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
HFAPHBKH_02950	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
HFAPHBKH_02951	1.16e-270	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
HFAPHBKH_02952	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
HFAPHBKH_02953	5.29e-307	ygxB	-	-	M	-	-	-	Conserved TM helix
HFAPHBKH_02954	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
HFAPHBKH_02956	4.37e-131	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HFAPHBKH_02957	3e-71	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
HFAPHBKH_02958	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFAPHBKH_02959	1.22e-249	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HFAPHBKH_02960	1.5e-81	-	-	-	S	-	-	-	Immunity protein 70
HFAPHBKH_02964	5.03e-53	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
HFAPHBKH_02966	4.39e-37	yddA	-	-	-	-	-	-	-
HFAPHBKH_02970	2.61e-223	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
HFAPHBKH_02971	9.78e-54	yddC	-	-	-	-	-	-	-
HFAPHBKH_02972	6.91e-118	yddD	-	-	S	-	-	-	TcpE family
HFAPHBKH_02973	2.61e-269	yddE	-	-	S	-	-	-	AAA-like domain
HFAPHBKH_02974	2.21e-242	yddE	-	-	S	-	-	-	AAA-like domain
HFAPHBKH_02975	1.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
HFAPHBKH_02976	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
HFAPHBKH_02977	1.03e-237	yddH	-	-	M	-	-	-	Lysozyme-like
HFAPHBKH_02978	3.19e-111	yddI	-	-	-	-	-	-	-
HFAPHBKH_02979	3.04e-87	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
HFAPHBKH_02980	2.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
HFAPHBKH_02981	2.52e-149	ywaC	2.7.6.5	-	S	ko:K00951,ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	protein conserved in bacteria
HFAPHBKH_02982	7.02e-128	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
HFAPHBKH_02983	5.85e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
HFAPHBKH_02984	1.01e-64	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
HFAPHBKH_02985	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
HFAPHBKH_02986	4.87e-34	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFAPHBKH_02987	1.39e-107	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFAPHBKH_02988	1.91e-245	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
HFAPHBKH_02989	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
HFAPHBKH_02990	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
HFAPHBKH_02991	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
HFAPHBKH_02992	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HFAPHBKH_02993	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
HFAPHBKH_02994	1.64e-94	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
HFAPHBKH_02995	3.88e-140	yvgT	-	-	S	-	-	-	membrane
HFAPHBKH_02996	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
HFAPHBKH_02997	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HFAPHBKH_02998	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HFAPHBKH_02999	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
HFAPHBKH_03000	9.32e-112	yvgO	-	-	-	-	-	-	-
HFAPHBKH_03001	6.19e-201	yvgN	-	-	S	-	-	-	reductase
HFAPHBKH_03002	1.01e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
HFAPHBKH_03003	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
HFAPHBKH_03004	2.97e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
HFAPHBKH_03005	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
HFAPHBKH_03006	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
HFAPHBKH_03007	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
HFAPHBKH_03008	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
HFAPHBKH_03010	2.57e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFAPHBKH_03011	4.04e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_03012	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_03013	6.89e-190	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFAPHBKH_03014	3.44e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
HFAPHBKH_03015	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03016	3.36e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFAPHBKH_03017	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
HFAPHBKH_03018	3.76e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HFAPHBKH_03019	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
HFAPHBKH_03020	6.67e-125	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
HFAPHBKH_03021	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_03022	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
HFAPHBKH_03023	1.32e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
HFAPHBKH_03025	6.92e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
HFAPHBKH_03026	2.57e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
HFAPHBKH_03027	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
HFAPHBKH_03028	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
HFAPHBKH_03029	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFAPHBKH_03030	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
HFAPHBKH_03031	2.02e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
HFAPHBKH_03032	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
HFAPHBKH_03033	9.86e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
HFAPHBKH_03034	1.14e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFAPHBKH_03035	9.59e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
HFAPHBKH_03036	2.45e-268	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
HFAPHBKH_03037	6.93e-49	yrhC	-	-	S	-	-	-	YrhC-like protein
HFAPHBKH_03038	6.05e-103	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
HFAPHBKH_03039	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
HFAPHBKH_03040	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
HFAPHBKH_03042	1.13e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
HFAPHBKH_03044	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
HFAPHBKH_03045	1.88e-118	yrhH	-	-	Q	-	-	-	methyltransferase
HFAPHBKH_03046	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
HFAPHBKH_03047	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
HFAPHBKH_03048	6.32e-59	yrhK	-	-	S	-	-	-	YrhK-like protein
HFAPHBKH_03049	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
HFAPHBKH_03050	7.4e-193	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
HFAPHBKH_03051	3.16e-51	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_03052	8.25e-49	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_03053	1.98e-192	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
HFAPHBKH_03054	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
HFAPHBKH_03055	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_03056	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
HFAPHBKH_03057	2.66e-97	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
HFAPHBKH_03058	7.63e-107	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
HFAPHBKH_03059	1.75e-167	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HFAPHBKH_03060	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HFAPHBKH_03061	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
HFAPHBKH_03062	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HFAPHBKH_03063	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
HFAPHBKH_03064	1.76e-39	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
HFAPHBKH_03065	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
HFAPHBKH_03066	4.9e-64	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
HFAPHBKH_03067	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
HFAPHBKH_03068	3.71e-283	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HFAPHBKH_03069	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
HFAPHBKH_03070	4.04e-48	yraG	-	-	-	ko:K06440	-	ko00000	-
HFAPHBKH_03071	1.1e-85	-	-	-	E	-	-	-	Glyoxalase-like domain
HFAPHBKH_03072	1.05e-81	-	-	-	T	-	-	-	sh3 domain protein
HFAPHBKH_03073	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
HFAPHBKH_03074	2.61e-172	-	-	-	S	-	-	-	Alpha beta hydrolase
HFAPHBKH_03075	8.42e-55	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_03076	2.2e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HFAPHBKH_03077	5.72e-238	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
HFAPHBKH_03078	3.7e-123	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_03079	6.26e-168	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HFAPHBKH_03081	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
HFAPHBKH_03082	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
HFAPHBKH_03083	2.45e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HFAPHBKH_03084	1.48e-212	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
HFAPHBKH_03085	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
HFAPHBKH_03087	1.09e-73	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
HFAPHBKH_03088	7.38e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
HFAPHBKH_03090	5.51e-283	cypA	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFAPHBKH_03091	3.92e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
HFAPHBKH_03092	4.45e-99	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
HFAPHBKH_03093	2.1e-117	azlC	-	-	E	-	-	-	AzlC protein
HFAPHBKH_03094	2.79e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
HFAPHBKH_03095	9.63e-290	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
HFAPHBKH_03097	9.05e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
HFAPHBKH_03098	1.23e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
HFAPHBKH_03099	1.4e-203	-	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03100	3.17e-212	yrdR	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_03101	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
HFAPHBKH_03102	1.02e-297	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
HFAPHBKH_03103	5.5e-37	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
HFAPHBKH_03104	1.89e-40	-	-	-	-	-	-	-	-
HFAPHBKH_03106	5.08e-26	xkdM	-	-	S	-	-	-	Phage tail tube protein
HFAPHBKH_03107	2.43e-14	-	-	-	-	-	-	-	-
HFAPHBKH_03110	7.44e-05	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
HFAPHBKH_03113	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
HFAPHBKH_03114	1.79e-267	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_03115	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
HFAPHBKH_03116	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFAPHBKH_03117	8.03e-81	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFAPHBKH_03118	2.01e-267	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
HFAPHBKH_03119	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
HFAPHBKH_03120	1.82e-275	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HFAPHBKH_03121	3.3e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HFAPHBKH_03122	1.88e-254	-	-	-	L	-	-	-	COG3666 Transposase and inactivated derivatives
HFAPHBKH_03124	1.92e-47	-	-	-	-	-	-	-	-
HFAPHBKH_03125	2.28e-25	-	-	-	-	-	-	-	-
HFAPHBKH_03126	2.49e-07	-	-	-	-	-	-	-	-
HFAPHBKH_03127	3.01e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
HFAPHBKH_03128	2.43e-58	yjcN	-	-	-	-	-	-	-
HFAPHBKH_03129	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
HFAPHBKH_03130	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_03131	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFAPHBKH_03132	3.33e-72	yjdF3	-	-	S	-	-	-	Protein of unknown function (DUF2992)
HFAPHBKH_03133	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
HFAPHBKH_03134	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_03135	4.34e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFAPHBKH_03137	1.22e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
HFAPHBKH_03138	7.54e-22	-	-	-	-	-	-	-	-
HFAPHBKH_03141	7.89e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFAPHBKH_03143	2.43e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
HFAPHBKH_03146	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
HFAPHBKH_03147	8.92e-96	-	-	-	-	-	-	-	-
HFAPHBKH_03148	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
HFAPHBKH_03151	9.36e-65	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFAPHBKH_03152	1.82e-181	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFAPHBKH_03153	5.45e-112	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
HFAPHBKH_03154	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
HFAPHBKH_03155	2.87e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
HFAPHBKH_03156	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
HFAPHBKH_03159	1.55e-173	yndL	-	-	S	-	-	-	Replication protein
HFAPHBKH_03160	3.11e-95	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
HFAPHBKH_03161	5.34e-97	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HFAPHBKH_03162	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFAPHBKH_03163	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HFAPHBKH_03164	5.4e-143	yneB	-	-	L	-	-	-	resolvase
HFAPHBKH_03165	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
HFAPHBKH_03166	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFAPHBKH_03167	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
HFAPHBKH_03168	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
HFAPHBKH_03169	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
HFAPHBKH_03170	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
HFAPHBKH_03171	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
HFAPHBKH_03172	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
HFAPHBKH_03173	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
HFAPHBKH_03174	7.02e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
HFAPHBKH_03175	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
HFAPHBKH_03176	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
HFAPHBKH_03177	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFAPHBKH_03178	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HFAPHBKH_03179	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
HFAPHBKH_03181	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
HFAPHBKH_03182	1.15e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
HFAPHBKH_03183	2.71e-70	yneQ	-	-	-	-	-	-	-
HFAPHBKH_03184	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
HFAPHBKH_03185	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFAPHBKH_03186	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
HFAPHBKH_03187	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFAPHBKH_03188	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFAPHBKH_03189	1.82e-18	-	-	-	-	-	-	-	-
HFAPHBKH_03190	8.74e-75	ynfC	-	-	-	-	-	-	-
HFAPHBKH_03191	6.11e-302	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
HFAPHBKH_03192	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
HFAPHBKH_03194	2.36e-315	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
HFAPHBKH_03195	7.79e-269	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HFAPHBKH_03196	5.64e-35	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
HFAPHBKH_03197	1.72e-103	yngA	-	-	S	-	-	-	membrane
HFAPHBKH_03198	4.54e-209	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
HFAPHBKH_03199	2.01e-134	yngC	-	-	S	-	-	-	membrane-associated protein
HFAPHBKH_03200	1.23e-294	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
HFAPHBKH_03201	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HFAPHBKH_03202	4.96e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
HFAPHBKH_03203	1.12e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
HFAPHBKH_03204	7.15e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
HFAPHBKH_03205	2.81e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
HFAPHBKH_03206	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HFAPHBKH_03207	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HFAPHBKH_03208	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
HFAPHBKH_03209	1.01e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
HFAPHBKH_03210	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
HFAPHBKH_03211	8.82e-37	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
HFAPHBKH_03212	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFAPHBKH_03213	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
HFAPHBKH_03214	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
HFAPHBKH_03215	1.14e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
HFAPHBKH_03216	8.34e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
HFAPHBKH_03218	1.14e-124	-	-	-	L	-	-	-	Integrase
HFAPHBKH_03219	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
HFAPHBKH_03220	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
HFAPHBKH_03221	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03222	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HFAPHBKH_03223	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HFAPHBKH_03224	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
HFAPHBKH_03225	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03226	2.05e-173	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFAPHBKH_03227	3.43e-100	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFAPHBKH_03228	1.07e-54	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFAPHBKH_03229	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HFAPHBKH_03230	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03231	8.07e-53	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
HFAPHBKH_03232	7.05e-172	yoxB	-	-	-	-	-	-	-
HFAPHBKH_03233	2.31e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFAPHBKH_03234	6.24e-168	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFAPHBKH_03235	2.92e-120	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
HFAPHBKH_03236	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
HFAPHBKH_03237	8.15e-105	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
HFAPHBKH_03238	2.24e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
HFAPHBKH_03239	2.23e-112	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
HFAPHBKH_03240	7.71e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_03241	0.0	-	-	-	I	-	-	-	PLD-like domain
HFAPHBKH_03242	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_03243	1.38e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
HFAPHBKH_03244	2.67e-191	-	-	-	S	-	-	-	membrane
HFAPHBKH_03245	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HFAPHBKH_03246	4.34e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
HFAPHBKH_03247	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
HFAPHBKH_03248	5.84e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
HFAPHBKH_03249	8.11e-62	-	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFAPHBKH_03250	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
HFAPHBKH_03252	9.14e-206	-	-	-	P	-	-	-	Catalase
HFAPHBKH_03253	4.26e-33	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
HFAPHBKH_03254	2.28e-13	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
HFAPHBKH_03255	3.4e-193	-	-	-	EG	-	-	-	Spore germination protein
HFAPHBKH_03256	5.09e-42	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HFAPHBKH_03257	2.2e-100	-	-	-	-	-	-	-	-
HFAPHBKH_03258	2.72e-59	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
HFAPHBKH_03259	1.88e-19	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
HFAPHBKH_03260	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
HFAPHBKH_03261	3.56e-169	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
HFAPHBKH_03262	1.79e-145	yoaK	-	-	S	-	-	-	Membrane
HFAPHBKH_03263	2.19e-247	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
HFAPHBKH_03264	2.28e-67	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
HFAPHBKH_03267	1.45e-207	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HFAPHBKH_03268	2.59e-64	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
HFAPHBKH_03271	8.19e-108	-	-	-	-	-	-	-	-
HFAPHBKH_03272	1.42e-215	yoaR	-	-	V	-	-	-	vancomycin resistance protein
HFAPHBKH_03273	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
HFAPHBKH_03274	7e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03275	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
HFAPHBKH_03276	1.35e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
HFAPHBKH_03277	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
HFAPHBKH_03278	1.89e-100	yoaW	-	-	-	-	-	-	-
HFAPHBKH_03279	4.88e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
HFAPHBKH_03280	8.51e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
HFAPHBKH_03283	0.0	pps	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	phosphoenolpyruvate synthase
HFAPHBKH_03284	2.16e-156	xlnB	3.2.1.8	-	G	ko:K01181	-	ko00000,ko01000	Glycosyl hydrolases family 11
HFAPHBKH_03285	2.11e-49	-	-	-	S	-	-	-	TM2 domain
HFAPHBKH_03286	1.73e-70	-	-	-	K	-	-	-	Helix-turn-helix
HFAPHBKH_03289	1.45e-38	-	-	-	-	-	-	-	-
HFAPHBKH_03290	3.12e-174	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
HFAPHBKH_03291	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03292	1.39e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
HFAPHBKH_03293	2.97e-143	ykoF	-	-	S	-	-	-	YKOF-related Family
HFAPHBKH_03294	1.23e-158	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_03295	4.78e-203	ykoH	-	-	T	-	-	-	Histidine kinase
HFAPHBKH_03296	2.94e-84	ykoH	-	-	T	-	-	-	Histidine kinase
HFAPHBKH_03297	1.3e-90	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFAPHBKH_03298	3.72e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
HFAPHBKH_03299	1.45e-08	-	-	-	-	-	-	-	-
HFAPHBKH_03301	1.99e-299	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
HFAPHBKH_03302	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
HFAPHBKH_03303	1.63e-25	-	-	-	-	-	-	-	-
HFAPHBKH_03304	3.04e-36	ykoL	-	-	-	-	-	-	-
HFAPHBKH_03305	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HFAPHBKH_03306	4.75e-91	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HFAPHBKH_03307	7.02e-116	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HFAPHBKH_03308	1.44e-128	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
HFAPHBKH_03309	2.07e-196	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
HFAPHBKH_03310	0.0	ykoS	-	-	-	-	-	-	-
HFAPHBKH_03311	3.86e-237	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFAPHBKH_03312	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
HFAPHBKH_03313	7.24e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HFAPHBKH_03314	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
HFAPHBKH_03315	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
HFAPHBKH_03316	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HFAPHBKH_03317	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HFAPHBKH_03318	3.83e-204	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
HFAPHBKH_03319	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
HFAPHBKH_03320	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
HFAPHBKH_03321	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
HFAPHBKH_03322	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
HFAPHBKH_03324	4.83e-30	ykzE	-	-	-	-	-	-	-
HFAPHBKH_03325	4.75e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
HFAPHBKH_03326	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_03327	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFAPHBKH_03329	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HFAPHBKH_03330	7.07e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HFAPHBKH_03331	3.86e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HFAPHBKH_03332	6.84e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFAPHBKH_03333	3.25e-293	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HFAPHBKH_03334	7.2e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HFAPHBKH_03335	1.24e-144	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HFAPHBKH_03336	1.02e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HFAPHBKH_03337	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
HFAPHBKH_03339	5.87e-74	eag	-	-	-	-	-	-	-
HFAPHBKH_03340	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HFAPHBKH_03341	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
HFAPHBKH_03342	1.51e-166	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
HFAPHBKH_03343	9.19e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
HFAPHBKH_03344	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
HFAPHBKH_03345	1.94e-226	ykvI	-	-	S	-	-	-	membrane
HFAPHBKH_03346	1.07e-159	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HFAPHBKH_03347	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
HFAPHBKH_03348	1.69e-177	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HFAPHBKH_03349	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HFAPHBKH_03350	5.19e-60	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
HFAPHBKH_03351	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03352	2.6e-39	-	-	-	-	-	-	-	-
HFAPHBKH_03353	1.83e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
HFAPHBKH_03354	6.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFAPHBKH_03355	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
HFAPHBKH_03356	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
HFAPHBKH_03357	3.99e-09	-	-	-	-	-	-	-	-
HFAPHBKH_03358	3.19e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
HFAPHBKH_03359	1.1e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03361	2.79e-167	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
HFAPHBKH_03362	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_03363	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
HFAPHBKH_03364	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFAPHBKH_03365	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03366	2.49e-256	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
HFAPHBKH_03367	3.59e-161	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFAPHBKH_03368	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
HFAPHBKH_03369	6.67e-202	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HFAPHBKH_03370	6.75e-306	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HFAPHBKH_03371	3.54e-199	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
HFAPHBKH_03372	4.58e-215	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HFAPHBKH_03373	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
HFAPHBKH_03374	7.46e-176	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
HFAPHBKH_03375	2.83e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
HFAPHBKH_03376	4.42e-216	bsn	-	-	L	-	-	-	Ribonuclease
HFAPHBKH_03377	4.82e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HFAPHBKH_03378	9.52e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HFAPHBKH_03379	7.18e-234	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HFAPHBKH_03380	8.43e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
HFAPHBKH_03381	2.47e-187	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HFAPHBKH_03382	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HFAPHBKH_03383	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HFAPHBKH_03384	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HFAPHBKH_03385	2.09e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HFAPHBKH_03386	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HFAPHBKH_03387	1.07e-273	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
HFAPHBKH_03388	1.56e-295	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
HFAPHBKH_03389	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
HFAPHBKH_03390	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HFAPHBKH_03391	2.72e-82	yunG	-	-	-	-	-	-	-
HFAPHBKH_03392	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
HFAPHBKH_03393	6.51e-181	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFAPHBKH_03394	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFAPHBKH_03395	5.67e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
HFAPHBKH_03396	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
HFAPHBKH_03397	1.08e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
HFAPHBKH_03398	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFAPHBKH_03399	1.34e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFAPHBKH_03400	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03401	1.61e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
HFAPHBKH_03402	2.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFAPHBKH_03403	2.26e-101	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
HFAPHBKH_03404	1.55e-253	yutH	-	-	S	-	-	-	Spore coat protein
HFAPHBKH_03405	1.67e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
HFAPHBKH_03406	3.97e-252	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HFAPHBKH_03407	2.57e-221	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HFAPHBKH_03408	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
HFAPHBKH_03409	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
HFAPHBKH_03410	2.22e-73	yuzD	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03411	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFAPHBKH_03412	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
HFAPHBKH_03413	1.04e-268	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HFAPHBKH_03414	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFAPHBKH_03415	2.78e-82	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
HFAPHBKH_03416	3.74e-122	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
HFAPHBKH_03417	6.4e-235	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFAPHBKH_03419	6.7e-240	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
HFAPHBKH_03420	4.16e-301	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
HFAPHBKH_03421	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
HFAPHBKH_03422	2.69e-150	yuiC	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03424	7.23e-99	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
HFAPHBKH_03425	5.09e-304	pre	-	-	D	-	-	-	plasmid recombination enzyme
HFAPHBKH_03426	1.81e-108	-	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03428	2.37e-251	-	-	-	L	-	-	-	Replication protein
HFAPHBKH_03432	6.12e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
HFAPHBKH_03433	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
HFAPHBKH_03434	9.87e-212	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFAPHBKH_03435	1.25e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03436	1.54e-154	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03437	1.67e-79	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03438	8.31e-69	-	-	-	-	-	-	-	-
HFAPHBKH_03439	3.95e-59	yhcC	-	-	-	-	-	-	-
HFAPHBKH_03440	4.87e-128	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
HFAPHBKH_03441	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
HFAPHBKH_03442	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
HFAPHBKH_03443	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
HFAPHBKH_03444	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
HFAPHBKH_03445	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
HFAPHBKH_03446	3.01e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HFAPHBKH_03447	1.25e-93	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
HFAPHBKH_03448	3.73e-133	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
HFAPHBKH_03449	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFAPHBKH_03450	4.41e-222	yhbB	-	-	S	-	-	-	Putative amidase domain
HFAPHBKH_03451	9.85e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HFAPHBKH_03452	1.58e-146	yhzB	-	-	S	-	-	-	B3/4 domain
HFAPHBKH_03454	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03455	3.81e-100	ygaO	-	-	-	-	-	-	-
HFAPHBKH_03456	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFAPHBKH_03458	1.09e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
HFAPHBKH_03459	3.79e-186	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HFAPHBKH_03460	2.08e-218	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
HFAPHBKH_03461	2.06e-185	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HFAPHBKH_03462	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HFAPHBKH_03464	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HFAPHBKH_03465	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
HFAPHBKH_03466	1.58e-36	-	-	-	-	-	-	-	-
HFAPHBKH_03467	1.5e-183	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
HFAPHBKH_03468	1.18e-178	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03469	1.41e-216	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HFAPHBKH_03470	1.56e-235	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_03471	5.43e-311	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HFAPHBKH_03472	7.88e-131	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
HFAPHBKH_03473	1.53e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_03474	2.12e-65	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
HFAPHBKH_03475	1.41e-142	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HFAPHBKH_03476	8.15e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
HFAPHBKH_03477	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
HFAPHBKH_03478	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_03479	8.64e-137	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HFAPHBKH_03480	8.23e-236	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
HFAPHBKH_03481	3.24e-250	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
HFAPHBKH_03482	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
HFAPHBKH_03483	1.06e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
HFAPHBKH_03484	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFAPHBKH_03485	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03486	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_03487	6.4e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_03488	2.17e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFAPHBKH_03489	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
HFAPHBKH_03490	2.71e-176	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03491	5.75e-160	-	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFAPHBKH_03492	1.26e-18	-	-	-	-	-	-	-	-
HFAPHBKH_03494	3.05e-20	-	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HFAPHBKH_03496	2.94e-17	-	-	-	EGP	-	-	-	Major Facilitator
HFAPHBKH_03497	6.4e-09	-	-	-	J	-	-	-	O-methyltransferase
HFAPHBKH_03498	3.54e-95	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC superfamily ATP binding cassette transporter ABC protein
HFAPHBKH_03499	2.98e-14	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
HFAPHBKH_03501	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
HFAPHBKH_03502	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
HFAPHBKH_03503	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFAPHBKH_03504	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
HFAPHBKH_03505	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
HFAPHBKH_03506	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03507	4.86e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
HFAPHBKH_03508	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
HFAPHBKH_03509	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
HFAPHBKH_03510	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
HFAPHBKH_03511	2.23e-54	-	-	-	-	-	-	-	-
HFAPHBKH_03512	1.41e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
HFAPHBKH_03513	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
HFAPHBKH_03514	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
HFAPHBKH_03515	1.82e-276	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
HFAPHBKH_03516	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
HFAPHBKH_03517	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
HFAPHBKH_03518	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HFAPHBKH_03519	2.11e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
HFAPHBKH_03520	8.9e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
HFAPHBKH_03521	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
HFAPHBKH_03522	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
HFAPHBKH_03523	1.76e-235	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFAPHBKH_03524	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
HFAPHBKH_03525	5.86e-189	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
HFAPHBKH_03526	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFAPHBKH_03527	3.82e-183	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HFAPHBKH_03528	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
HFAPHBKH_03529	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFAPHBKH_03530	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
HFAPHBKH_03531	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
HFAPHBKH_03532	5.91e-85	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFAPHBKH_03533	3.35e-56	-	-	-	-	-	-	-	-
HFAPHBKH_03535	2.63e-264	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
HFAPHBKH_03536	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
HFAPHBKH_03537	2.24e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HFAPHBKH_03554	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
HFAPHBKH_03555	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
HFAPHBKH_03556	8.77e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
HFAPHBKH_03557	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
HFAPHBKH_03558	4.59e-307	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
HFAPHBKH_03559	8.84e-206	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
HFAPHBKH_03560	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
HFAPHBKH_03561	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFAPHBKH_03562	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFAPHBKH_03563	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
HFAPHBKH_03564	8.28e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
HFAPHBKH_03565	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFAPHBKH_03566	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
HFAPHBKH_03567	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
HFAPHBKH_03568	1.51e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HFAPHBKH_03569	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HFAPHBKH_03570	5.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFAPHBKH_03571	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HFAPHBKH_03572	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
HFAPHBKH_03574	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
HFAPHBKH_03575	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
HFAPHBKH_03576	2.15e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
HFAPHBKH_03577	4.48e-35	ykzI	-	-	-	-	-	-	-
HFAPHBKH_03578	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
HFAPHBKH_03579	1.17e-97	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
HFAPHBKH_03580	1.01e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HFAPHBKH_03581	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
HFAPHBKH_03582	0.0	ylaA	-	-	-	-	-	-	-
HFAPHBKH_03583	1.44e-56	ylaB	-	-	-	-	-	-	-
HFAPHBKH_03584	1.79e-56	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_03587	2.14e-17	-	-	-	Q	-	-	-	methyltransferase
HFAPHBKH_03588	4.01e-33	-	2.7.7.80	-	H	ko:K21029	ko04122,map04122	ko00000,ko00001,ko01000	ThiF family
HFAPHBKH_03589	0.000751	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Methyltransferase small domain
HFAPHBKH_03590	3.91e-52	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HFAPHBKH_03592	1.57e-121	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
HFAPHBKH_03594	4.46e-23	-	-	-	-	-	-	-	-
HFAPHBKH_03595	3.2e-59	yoaQ	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
HFAPHBKH_03596	7.66e-99	-	-	-	-	-	-	-	-
HFAPHBKH_03597	3.46e-10	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HFAPHBKH_03598	4.98e-106	yoaW	-	-	-	-	-	-	-
HFAPHBKH_03599	4.01e-36	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
HFAPHBKH_03601	1.4e-104	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
HFAPHBKH_03602	4.82e-69	ynaF	-	-	-	-	-	-	-
HFAPHBKH_03604	3.11e-12	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
HFAPHBKH_03606	0.0	-	-	-	V	-	-	-	Beta-lactamase
HFAPHBKH_03610	6.14e-142	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
HFAPHBKH_03613	1.55e-235	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HFAPHBKH_03616	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03617	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFAPHBKH_03618	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFAPHBKH_03619	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFAPHBKH_03620	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
HFAPHBKH_03621	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
HFAPHBKH_03622	5.35e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
HFAPHBKH_03623	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HFAPHBKH_03624	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
HFAPHBKH_03625	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFAPHBKH_03626	1.43e-143	yrbG	-	-	S	-	-	-	membrane
HFAPHBKH_03627	8.81e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
HFAPHBKH_03628	1.24e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
HFAPHBKH_03629	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFAPHBKH_03630	2.46e-247	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HFAPHBKH_03631	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
HFAPHBKH_03632	3.72e-238	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFAPHBKH_03633	1.64e-136	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFAPHBKH_03634	1.3e-120	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
HFAPHBKH_03635	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
HFAPHBKH_03636	1.53e-245	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
HFAPHBKH_03637	2.92e-23	yrzF	-	-	T	-	-	-	serine threonine protein kinase
HFAPHBKH_03638	8.28e-85	yrzF	-	-	T	-	-	-	serine threonine protein kinase
HFAPHBKH_03640	3.62e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
HFAPHBKH_03641	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HFAPHBKH_03642	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
HFAPHBKH_03643	5.13e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFAPHBKH_03644	3.45e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
HFAPHBKH_03645	2.55e-269	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFAPHBKH_03646	1.02e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
HFAPHBKH_03647	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
HFAPHBKH_03648	7.06e-292	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
HFAPHBKH_03649	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
HFAPHBKH_03650	2.54e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
HFAPHBKH_03651	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
HFAPHBKH_03652	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFAPHBKH_03653	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
HFAPHBKH_03654	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
HFAPHBKH_03655	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
HFAPHBKH_03656	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
HFAPHBKH_03657	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
HFAPHBKH_03658	7.44e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
HFAPHBKH_03659	4.13e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
HFAPHBKH_03660	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HFAPHBKH_03661	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
HFAPHBKH_03662	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
HFAPHBKH_03663	2.14e-234	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
HFAPHBKH_03664	4.93e-65	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
HFAPHBKH_03666	4.72e-160	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
HFAPHBKH_03667	1.62e-233	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
HFAPHBKH_03668	3.62e-86	-	-	-	S	-	-	-	Immunity protein 70
HFAPHBKH_03669	3.4e-146	-	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
HFAPHBKH_03671	9.14e-317	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
HFAPHBKH_03672	1.28e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFAPHBKH_03673	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03674	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
HFAPHBKH_03675	5.37e-216	gspA	-	-	M	-	-	-	General stress
HFAPHBKH_03682	7.47e-233	yaaC	-	-	S	-	-	-	YaaC-like Protein
HFAPHBKH_03683	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HFAPHBKH_03684	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
HFAPHBKH_03685	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HFAPHBKH_03686	9.58e-138	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HFAPHBKH_03687	9.79e-296	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFAPHBKH_03689	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
HFAPHBKH_03690	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
HFAPHBKH_03691	2.74e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
HFAPHBKH_03692	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
HFAPHBKH_03693	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFAPHBKH_03694	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFAPHBKH_03695	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFAPHBKH_03696	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFAPHBKH_03697	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
HFAPHBKH_03698	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
HFAPHBKH_03708	7.95e-220	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
HFAPHBKH_03709	2.53e-241	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03710	7.92e-307	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
HFAPHBKH_03711	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
HFAPHBKH_03712	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
HFAPHBKH_03713	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
HFAPHBKH_03714	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
HFAPHBKH_03715	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
HFAPHBKH_03716	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
HFAPHBKH_03717	1.49e-180	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HFAPHBKH_03718	4.05e-267	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
HFAPHBKH_03719	5.75e-78	yttA	-	-	S	-	-	-	Pfam Transposase IS66
HFAPHBKH_03720	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
HFAPHBKH_03721	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03722	4.53e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
HFAPHBKH_03723	2.14e-165	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HFAPHBKH_03724	9.81e-297	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFAPHBKH_03725	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03726	1.37e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
HFAPHBKH_03727	4.87e-215	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
HFAPHBKH_03728	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03729	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
HFAPHBKH_03731	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
HFAPHBKH_03732	2.35e-244	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
HFAPHBKH_03733	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
HFAPHBKH_03734	4.81e-276	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
HFAPHBKH_03735	6.67e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
HFAPHBKH_03736	1.13e-85	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HFAPHBKH_03737	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
HFAPHBKH_03738	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
HFAPHBKH_03739	3.07e-284	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFAPHBKH_03740	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HFAPHBKH_03741	5.75e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
HFAPHBKH_03742	9.48e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HFAPHBKH_03743	2.77e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HFAPHBKH_03744	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
HFAPHBKH_03745	1.32e-183	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HFAPHBKH_03746	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
HFAPHBKH_03747	7.55e-80	ytkC	-	-	S	-	-	-	Bacteriophage holin family
HFAPHBKH_03748	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
HFAPHBKH_03750	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
HFAPHBKH_03751	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFAPHBKH_03752	1.27e-133	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
HFAPHBKH_03753	1.44e-55	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
HFAPHBKH_03754	3e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
HFAPHBKH_03755	4.02e-239	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HFAPHBKH_03756	9.9e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
HFAPHBKH_03757	7.59e-191	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HFAPHBKH_03758	5.85e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HFAPHBKH_03759	9.74e-176	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HFAPHBKH_03760	3.77e-217	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
HFAPHBKH_03761	1.94e-270	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HFAPHBKH_03762	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFAPHBKH_03763	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFAPHBKH_03764	4.49e-193	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HFAPHBKH_03765	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HFAPHBKH_03766	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
HFAPHBKH_03767	2.49e-168	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
HFAPHBKH_03768	6.65e-194	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
HFAPHBKH_03769	6.8e-309	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HFAPHBKH_03770	2.78e-224	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
HFAPHBKH_03771	9.54e-288	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
HFAPHBKH_03773	6.65e-261	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
HFAPHBKH_03774	1.61e-272	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
HFAPHBKH_03775	3.68e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
HFAPHBKH_03776	6.09e-96	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
HFAPHBKH_03777	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HFAPHBKH_03778	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
HFAPHBKH_03779	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
HFAPHBKH_03780	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HFAPHBKH_03781	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HFAPHBKH_03803	3.01e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFAPHBKH_03804	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
HFAPHBKH_03805	3.3e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
HFAPHBKH_03806	1.14e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
HFAPHBKH_03807	1.81e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
HFAPHBKH_03808	1.37e-290	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFAPHBKH_03809	3.52e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HFAPHBKH_03810	3.24e-114	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
HFAPHBKH_03811	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
HFAPHBKH_03812	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
HFAPHBKH_03813	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
HFAPHBKH_03814	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
HFAPHBKH_03815	5.29e-199	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
HFAPHBKH_03816	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
HFAPHBKH_03817	8.32e-151	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
HFAPHBKH_03818	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
HFAPHBKH_03819	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_03820	1.78e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
HFAPHBKH_03821	1.05e-22	-	-	-	-	-	-	-	-
HFAPHBKH_03822	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
HFAPHBKH_03823	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
HFAPHBKH_03824	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_03825	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03826	3.48e-212	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
HFAPHBKH_03827	1.83e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_03828	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
HFAPHBKH_03829	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03830	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
HFAPHBKH_03831	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
HFAPHBKH_03832	6.01e-99	ykuL	-	-	S	-	-	-	CBS domain
HFAPHBKH_03833	7.61e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03834	6.35e-113	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
HFAPHBKH_03835	1.74e-222	ykuO	-	-	-	-	-	-	-
HFAPHBKH_03836	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
HFAPHBKH_03837	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFAPHBKH_03838	4.43e-273	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFAPHBKH_03839	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
HFAPHBKH_03840	2.37e-180	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
HFAPHBKH_03841	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
HFAPHBKH_03842	4.23e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
HFAPHBKH_03843	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
HFAPHBKH_03844	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
HFAPHBKH_03845	6.08e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
HFAPHBKH_03846	1.19e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
HFAPHBKH_03847	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
HFAPHBKH_03848	4.67e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFAPHBKH_03849	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_03850	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
HFAPHBKH_03851	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
HFAPHBKH_03852	5.2e-188	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
HFAPHBKH_03853	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
HFAPHBKH_03854	4.66e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
HFAPHBKH_03855	2.84e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
HFAPHBKH_03856	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFAPHBKH_03857	5.95e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
HFAPHBKH_03859	1.27e-20	-	-	-	S	-	-	-	D-Ala-teichoic acid biosynthesis protein
HFAPHBKH_03860	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFAPHBKH_03861	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
HFAPHBKH_03862	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFAPHBKH_03863	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFAPHBKH_03864	1.5e-60	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03865	1.22e-81	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
HFAPHBKH_03866	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
HFAPHBKH_03867	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HFAPHBKH_03868	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_03869	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFAPHBKH_03870	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
HFAPHBKH_03871	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
HFAPHBKH_03872	1.05e-26	yxzF	-	-	-	-	-	-	-
HFAPHBKH_03873	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
HFAPHBKH_03874	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
HFAPHBKH_03875	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
HFAPHBKH_03876	1.55e-176	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HFAPHBKH_03877	2.01e-211	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03878	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
HFAPHBKH_03879	1.63e-39	-	-	-	-	-	-	-	-
HFAPHBKH_03880	1.93e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
HFAPHBKH_03881	2.6e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
HFAPHBKH_03882	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
HFAPHBKH_03883	6.19e-201	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFAPHBKH_03884	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
HFAPHBKH_03885	6.35e-53	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
HFAPHBKH_03886	6.58e-300	-	-	-	-	-	-	-	-
HFAPHBKH_03887	1.22e-136	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
HFAPHBKH_03889	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
HFAPHBKH_03892	1.46e-33	-	-	-	-	-	-	-	-
HFAPHBKH_03894	8.3e-40	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
HFAPHBKH_03895	8.17e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
HFAPHBKH_03897	5.45e-13	-	-	-	-	-	-	-	-
HFAPHBKH_03898	7.58e-162	-	-	-	S	-	-	-	capsid protein
HFAPHBKH_03899	1.32e-92	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
HFAPHBKH_03900	1.33e-216	-	-	-	S	-	-	-	portal protein
HFAPHBKH_03902	1.19e-179	terL	-	-	S	-	-	-	Terminase
HFAPHBKH_03903	3.93e-73	-	-	-	L	-	-	-	Terminase, small subunit
HFAPHBKH_03909	2.62e-78	-	-	-	-	-	-	-	-
HFAPHBKH_03911	3.98e-25	-	-	-	S	-	-	-	YopX protein
HFAPHBKH_03913	6.85e-103	-	-	-	-	-	-	-	-
HFAPHBKH_03914	1.82e-120	-	-	-	S	-	-	-	nuclease activity
HFAPHBKH_03915	3.9e-85	-	-	-	-	-	-	-	-
HFAPHBKH_03916	0.0	-	-	-	S	-	-	-	hydrolase activity
HFAPHBKH_03917	3.5e-97	-	-	-	S	-	-	-	Protein of unknown function (DUF669)
HFAPHBKH_03918	1.15e-07	-	-	-	-	-	-	-	-
HFAPHBKH_03919	2.75e-217	-	-	-	S	-	-	-	AAA domain
HFAPHBKH_03920	8.9e-119	-	-	-	S	-	-	-	DNA protection
HFAPHBKH_03922	4.38e-29	-	-	-	S	-	-	-	Uncharacterized protein YqaH
HFAPHBKH_03925	1.62e-12	-	-	-	K	-	-	-	helix-turn-helix
HFAPHBKH_03926	4.93e-83	-	-	-	S	-	-	-	sequence-specific DNA binding
HFAPHBKH_03927	4.72e-92	-	-	-	S	-	-	-	Pfam:Peptidase_M78
HFAPHBKH_03928	2.55e-284	-	-	-	S	-	-	-	Recombinase
HFAPHBKH_03929	3.74e-211	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFAPHBKH_03930	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFAPHBKH_03931	5.43e-52	ykoA	-	-	-	-	-	-	-
HFAPHBKH_03932	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
HFAPHBKH_03933	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HFAPHBKH_03934	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
HFAPHBKH_03935	1.75e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_03936	5.51e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
HFAPHBKH_03937	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
HFAPHBKH_03938	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFAPHBKH_03939	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
HFAPHBKH_03940	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFAPHBKH_03941	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
HFAPHBKH_03942	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HFAPHBKH_03943	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
HFAPHBKH_03944	8.11e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
HFAPHBKH_03945	7.12e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
HFAPHBKH_03946	7.59e-245	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HFAPHBKH_03947	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HFAPHBKH_03948	9.46e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
HFAPHBKH_03949	4.54e-205	ytbE	-	-	S	-	-	-	reductase
HFAPHBKH_03950	5.44e-260	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
HFAPHBKH_03951	9.85e-88	ytcD	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_03952	1.22e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFAPHBKH_03953	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HFAPHBKH_03954	3.44e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFAPHBKH_03955	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
HFAPHBKH_03956	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
HFAPHBKH_03957	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
HFAPHBKH_03958	5.5e-202	ytxC	-	-	S	-	-	-	YtxC-like family
HFAPHBKH_03960	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFAPHBKH_03961	1.15e-188	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
HFAPHBKH_03962	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
HFAPHBKH_03963	4.62e-165	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
HFAPHBKH_03964	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HFAPHBKH_03965	5.34e-150	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HFAPHBKH_03967	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFAPHBKH_03968	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
HFAPHBKH_03969	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFAPHBKH_03970	1.27e-59	ysdA	-	-	S	-	-	-	Membrane
HFAPHBKH_03971	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
HFAPHBKH_03972	3.57e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
HFAPHBKH_03973	9.92e-242	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
HFAPHBKH_03974	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
HFAPHBKH_03975	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
HFAPHBKH_03976	6.93e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HFAPHBKH_03977	7.07e-186	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
HFAPHBKH_03978	3.72e-282	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HFAPHBKH_03979	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HFAPHBKH_03980	1.94e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
HFAPHBKH_03981	2.47e-189	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
HFAPHBKH_03982	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
HFAPHBKH_03983	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
HFAPHBKH_03985	8.17e-52	ysfE	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	lactoylglutathione lyase activity
HFAPHBKH_03986	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
HFAPHBKH_03987	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
HFAPHBKH_03988	1.24e-260	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
HFAPHBKH_03989	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
HFAPHBKH_03990	7.37e-170	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFAPHBKH_03991	1.81e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFAPHBKH_03992	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFAPHBKH_03993	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
HFAPHBKH_03994	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HFAPHBKH_03995	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFAPHBKH_03996	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HFAPHBKH_03997	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HFAPHBKH_03998	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
HFAPHBKH_03999	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
HFAPHBKH_04000	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFAPHBKH_04001	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFAPHBKH_04003	1.17e-148	-	-	-	-	-	-	-	-
HFAPHBKH_04004	5.53e-175	-	-	-	-	-	-	-	-
HFAPHBKH_04005	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
HFAPHBKH_04006	2.5e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
HFAPHBKH_04007	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
HFAPHBKH_04008	1.22e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
HFAPHBKH_04009	3.64e-59	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HFAPHBKH_04010	8.87e-76	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
HFAPHBKH_04011	1.42e-225	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFAPHBKH_04012	1.64e-86	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HFAPHBKH_04013	3.73e-64	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
HFAPHBKH_04014	6.97e-201	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
HFAPHBKH_04015	2.65e-246	-	-	-	S	-	-	-	Ion transport 2 domain protein
HFAPHBKH_04016	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFAPHBKH_04017	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
HFAPHBKH_04018	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
HFAPHBKH_04019	1.62e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
HFAPHBKH_04020	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFAPHBKH_04021	2e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HFAPHBKH_04022	2.8e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
HFAPHBKH_04023	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
HFAPHBKH_04024	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HFAPHBKH_04027	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
HFAPHBKH_04028	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
HFAPHBKH_04029	3.65e-81	ynaC	-	-	-	-	-	-	-
HFAPHBKH_04030	9.3e-51	ynaC	-	-	-	-	-	-	-
HFAPHBKH_04031	4.13e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
HFAPHBKH_04032	4.13e-51	-	-	-	-	-	-	-	-
HFAPHBKH_04033	1.46e-105	-	-	-	-	-	-	-	-
HFAPHBKH_04035	1.68e-13	-	-	-	-	-	-	-	-
HFAPHBKH_04037	4.6e-309	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
HFAPHBKH_04038	1.68e-53	-	-	-	-	-	-	-	-
HFAPHBKH_04039	3.69e-32	-	-	-	-	-	-	-	-
HFAPHBKH_04040	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
HFAPHBKH_04041	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
HFAPHBKH_04042	1.37e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HFAPHBKH_04043	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFAPHBKH_04044	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
HFAPHBKH_04045	2.72e-148	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
HFAPHBKH_04046	2.24e-141	-	-	-	-	-	-	-	-
HFAPHBKH_04047	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFAPHBKH_04048	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFAPHBKH_04049	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
HFAPHBKH_04050	1.2e-30	ymzA	-	-	-	-	-	-	-
HFAPHBKH_04051	1.63e-31	-	-	-	-	-	-	-	-
HFAPHBKH_04052	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HFAPHBKH_04053	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFAPHBKH_04054	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
HFAPHBKH_04056	2.45e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
HFAPHBKH_04057	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
HFAPHBKH_04058	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
HFAPHBKH_04059	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
HFAPHBKH_04061	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
HFAPHBKH_04062	1.88e-207	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
HFAPHBKH_04063	8.03e-81	ymzB	-	-	-	-	-	-	-
HFAPHBKH_04064	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_04065	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
HFAPHBKH_04066	2.23e-90	-	-	-	S	-	-	-	Regulatory protein YrvL
HFAPHBKH_04067	3.26e-72	-	-	-	L	-	-	-	transposase activity
HFAPHBKH_04068	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
HFAPHBKH_04069	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
HFAPHBKH_04070	1.34e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
HFAPHBKH_04071	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_04072	1.64e-12	-	-	-	-	-	-	-	-
HFAPHBKH_04073	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
HFAPHBKH_04074	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
HFAPHBKH_04075	9.78e-107	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFAPHBKH_04076	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
HFAPHBKH_04077	5.94e-264	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
HFAPHBKH_04078	1.83e-112	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
HFAPHBKH_04079	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
HFAPHBKH_04080	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
HFAPHBKH_04081	5.05e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
HFAPHBKH_04082	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
HFAPHBKH_04083	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_04084	1.36e-32	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
HFAPHBKH_04085	0.0	yflA	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
HFAPHBKH_04086	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
HFAPHBKH_04087	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
HFAPHBKH_04088	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HFAPHBKH_04089	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
HFAPHBKH_04090	1.73e-64	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
HFAPHBKH_04091	6.9e-27	yflI	-	-	-	-	-	-	-
HFAPHBKH_04092	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
HFAPHBKH_04093	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_04094	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
HFAPHBKH_04095	5.59e-275	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HFAPHBKH_04096	2.82e-191	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
HFAPHBKH_04097	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
HFAPHBKH_04098	1.31e-163	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HFAPHBKH_04099	7.81e-39	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
HFAPHBKH_04100	2.68e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
HFAPHBKH_04101	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
HFAPHBKH_04102	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
HFAPHBKH_04103	7.03e-307	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
HFAPHBKH_04104	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
HFAPHBKH_04105	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
HFAPHBKH_04106	1.94e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HFAPHBKH_04107	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_04108	2.98e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_04109	1.4e-192	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
HFAPHBKH_04110	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
HFAPHBKH_04111	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
HFAPHBKH_04112	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
HFAPHBKH_04113	7.22e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
HFAPHBKH_04114	6.3e-66	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
HFAPHBKH_04115	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
HFAPHBKH_04116	6.93e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
HFAPHBKH_04117	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
HFAPHBKH_04118	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
HFAPHBKH_04119	2.26e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
HFAPHBKH_04120	1.73e-48	yfhS	-	-	-	-	-	-	-
HFAPHBKH_04121	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HFAPHBKH_04122	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
HFAPHBKH_04123	2.01e-49	ygaB	-	-	S	-	-	-	YgaB-like protein
HFAPHBKH_04124	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
HFAPHBKH_04125	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
HFAPHBKH_04126	5.12e-236	ygaE	-	-	S	-	-	-	Membrane
HFAPHBKH_04127	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
HFAPHBKH_04128	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
HFAPHBKH_04129	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
HFAPHBKH_04130	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
HFAPHBKH_04131	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
HFAPHBKH_04133	2.13e-169	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
HFAPHBKH_04134	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HFAPHBKH_04135	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
HFAPHBKH_04136	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
HFAPHBKH_04137	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
HFAPHBKH_04138	2.57e-148	yteU	-	-	S	-	-	-	Integral membrane protein
HFAPHBKH_04139	5.75e-60	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HFAPHBKH_04140	1.83e-251	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
HFAPHBKH_04141	2.27e-92	yteS	-	-	G	-	-	-	transport
HFAPHBKH_04142	5.61e-277	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HFAPHBKH_04143	1.31e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
HFAPHBKH_04144	1.36e-202	ytdP	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_04145	5.52e-276	ytdP	-	-	K	-	-	-	Transcriptional regulator
HFAPHBKH_04146	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
HFAPHBKH_04147	1.02e-191	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
HFAPHBKH_04148	1.05e-176	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
HFAPHBKH_04149	6.39e-279	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
HFAPHBKH_04150	1.08e-242	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HFAPHBKH_04151	6.59e-160	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HFAPHBKH_04152	5.82e-272	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HFAPHBKH_04153	0.0	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HFAPHBKH_04154	1.11e-179	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HFAPHBKH_04155	1.28e-229	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
HFAPHBKH_04156	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_04157	1.42e-226	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFAPHBKH_04158	3.33e-209	yfhB	-	-	S	-	-	-	PhzF family
HFAPHBKH_04159	4.57e-135	yfhC	-	-	C	-	-	-	nitroreductase
HFAPHBKH_04160	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
HFAPHBKH_04162	1.73e-216	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
HFAPHBKH_04163	2.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
HFAPHBKH_04164	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
HFAPHBKH_04165	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HFAPHBKH_04166	1.4e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
HFAPHBKH_04167	1.86e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
HFAPHBKH_04168	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
HFAPHBKH_04170	9.96e-22	-	-	-	-	-	-	-	-
HFAPHBKH_04171	1.56e-300	-	-	-	I	-	-	-	Pfam Lipase (class 3)
HFAPHBKH_04172	1.62e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
HFAPHBKH_04173	2.51e-19	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
HFAPHBKH_04175	6.79e-11	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
HFAPHBKH_04177	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
HFAPHBKH_04178	1.24e-156	ydhC	-	-	K	-	-	-	FCD
HFAPHBKH_04179	5.08e-300	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
HFAPHBKH_04180	6.49e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HFAPHBKH_04181	4.28e-163	-	-	-	-	-	-	-	-
HFAPHBKH_04182	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
HFAPHBKH_04183	5.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
HFAPHBKH_04185	2.78e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
HFAPHBKH_04186	5.22e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
HFAPHBKH_04187	5.93e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
HFAPHBKH_04188	3.64e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
HFAPHBKH_04189	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_04190	2.31e-41	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
HFAPHBKH_04191	1.22e-173	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFAPHBKH_04192	1.2e-114	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFAPHBKH_04193	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
HFAPHBKH_04194	2.22e-170	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
HFAPHBKH_04195	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
HFAPHBKH_04196	1.07e-09	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFAPHBKH_04197	1.24e-76	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
HFAPHBKH_04198	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
HFAPHBKH_04199	9.18e-172	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
HFAPHBKH_04202	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
HFAPHBKH_04203	3.26e-36	yfjT	-	-	-	-	-	-	-
HFAPHBKH_04204	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
HFAPHBKH_04205	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
HFAPHBKH_04206	1e-255	-	-	-	L	-	-	-	Helix-turn-helix domain of resolvase
HFAPHBKH_04207	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
HFAPHBKH_04210	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
HFAPHBKH_04211	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
HFAPHBKH_04212	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
HFAPHBKH_04213	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFAPHBKH_04214	1.43e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
HFAPHBKH_04215	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
HFAPHBKH_04216	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
HFAPHBKH_04217	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
HFAPHBKH_04218	3.78e-88	ylbD	-	-	S	-	-	-	Putative coat protein
HFAPHBKH_04219	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
HFAPHBKH_04220	1.53e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
HFAPHBKH_04221	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
HFAPHBKH_04222	9.56e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
HFAPHBKH_04223	1.75e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HFAPHBKH_04224	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HFAPHBKH_04225	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFAPHBKH_04226	2.28e-250	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HFAPHBKH_04227	1.15e-206	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HFAPHBKH_04228	4.72e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HFAPHBKH_04229	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HFAPHBKH_04230	2.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
HFAPHBKH_04231	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
HFAPHBKH_04232	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
HFAPHBKH_04233	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HFAPHBKH_04234	1.41e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
HFAPHBKH_04235	2.44e-126	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HFAPHBKH_04236	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
HFAPHBKH_04237	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
HFAPHBKH_04238	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
HFAPHBKH_04239	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
HFAPHBKH_04240	1.74e-57	ylaE	-	-	-	-	-	-	-