ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
APGMFHAH_00001 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
APGMFHAH_00003 5.36e-203 ybaS - - S - - - Na -dependent transporter
APGMFHAH_00004 7.76e-182 ybbA - - S ko:K07017 - ko00000 Putative esterase
APGMFHAH_00005 1.43e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_00006 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_00007 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
APGMFHAH_00008 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
APGMFHAH_00009 2.33e-302 ybbC - - S - - - protein conserved in bacteria
APGMFHAH_00010 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
APGMFHAH_00011 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
APGMFHAH_00012 1.04e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_00013 3.51e-190 ybbH - - K - - - transcriptional
APGMFHAH_00014 5.5e-209 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APGMFHAH_00015 3.13e-114 ybbJ - - J - - - acetyltransferase
APGMFHAH_00016 2.43e-100 ybbK - - S - - - Protein of unknown function (DUF523)
APGMFHAH_00022 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_00023 2.73e-152 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
APGMFHAH_00024 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APGMFHAH_00025 5.59e-288 ybbR - - S - - - protein conserved in bacteria
APGMFHAH_00026 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APGMFHAH_00027 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
APGMFHAH_00028 5.87e-54 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APGMFHAH_00029 9.34e-128 alkA 3.2.2.21 - L ko:K01247,ko:K13529 ko03410,map03410 ko00000,ko00001,ko01000,ko03000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APGMFHAH_00030 6.2e-155 adaA - - K ko:K13530 - ko00000,ko01000,ko03000,ko03400 Transcriptional regulator
APGMFHAH_00031 1.06e-128 adaB 2.1.1.63 - L ko:K00567,ko:K10778,ko:K13531 - ko00000,ko01000,ko03000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APGMFHAH_00032 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APGMFHAH_00033 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
APGMFHAH_00034 7.77e-120 ybcF - - P - - - carbonic anhydrase
APGMFHAH_00036 4.6e-63 - - - - - - - -
APGMFHAH_00037 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
APGMFHAH_00038 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
APGMFHAH_00039 2.78e-219 - - - T - - - His Kinase A (phospho-acceptor) domain
APGMFHAH_00041 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
APGMFHAH_00042 1.49e-192 ybdN - - - - - - -
APGMFHAH_00043 7.06e-271 ybdO - - S - - - Domain of unknown function (DUF4885)
APGMFHAH_00044 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_00045 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
APGMFHAH_00046 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
APGMFHAH_00047 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
APGMFHAH_00048 2.46e-310 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
APGMFHAH_00049 1.28e-37 ybyB - - - - - - -
APGMFHAH_00050 0.0 ybeC - - E - - - amino acid
APGMFHAH_00051 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
APGMFHAH_00052 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
APGMFHAH_00053 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
APGMFHAH_00054 8.65e-202 ybfA - - K - - - FR47-like protein
APGMFHAH_00055 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_00056 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_00059 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
APGMFHAH_00060 1.06e-207 ybfH - - EG - - - EamA-like transporter family
APGMFHAH_00061 7.39e-188 ybfI - - K - - - AraC-like ligand binding domain
APGMFHAH_00062 3.63e-43 - - - K - - - sigma factor activity
APGMFHAH_00063 2.73e-28 xhlB - - S - - - SPP1 phage holin
APGMFHAH_00064 1.93e-122 - - GH19 M ko:K03791 - ko00000 Lysin motif
APGMFHAH_00065 2.61e-73 - - - - - - - -
APGMFHAH_00066 1.54e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
APGMFHAH_00067 3.97e-227 mpr - - M - - - Belongs to the peptidase S1B family
APGMFHAH_00069 1.31e-212 - - - S - - - Alpha/beta hydrolase family
APGMFHAH_00070 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APGMFHAH_00071 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
APGMFHAH_00072 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
APGMFHAH_00073 2.25e-59 ybfN - - - - - - -
APGMFHAH_00074 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
APGMFHAH_00075 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_00076 1.16e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
APGMFHAH_00079 5.24e-60 - - - - - - - -
APGMFHAH_00080 1.1e-20 - - - S - - - SMI1 / KNR4 family
APGMFHAH_00081 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
APGMFHAH_00083 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
APGMFHAH_00084 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
APGMFHAH_00085 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APGMFHAH_00086 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
APGMFHAH_00088 7.09e-88 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
APGMFHAH_00089 1.14e-197 yybE - - K - - - Transcriptional regulator
APGMFHAH_00090 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APGMFHAH_00091 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_00092 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
APGMFHAH_00093 7.4e-168 - - - - - - - -
APGMFHAH_00094 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
APGMFHAH_00095 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
APGMFHAH_00096 2.3e-174 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
APGMFHAH_00097 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
APGMFHAH_00099 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
APGMFHAH_00100 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
APGMFHAH_00101 4.01e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
APGMFHAH_00102 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
APGMFHAH_00103 5.83e-140 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APGMFHAH_00104 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
APGMFHAH_00105 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
APGMFHAH_00106 7.73e-176 yqeM - - Q - - - Methyltransferase
APGMFHAH_00107 1.1e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APGMFHAH_00108 3.85e-137 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
APGMFHAH_00109 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
APGMFHAH_00110 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
APGMFHAH_00111 2.36e-22 - - - S - - - YqzM-like protein
APGMFHAH_00112 6.73e-243 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
APGMFHAH_00113 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
APGMFHAH_00114 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
APGMFHAH_00115 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
APGMFHAH_00116 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
APGMFHAH_00117 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
APGMFHAH_00118 2.9e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
APGMFHAH_00119 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
APGMFHAH_00120 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APGMFHAH_00121 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
APGMFHAH_00122 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
APGMFHAH_00123 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
APGMFHAH_00124 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
APGMFHAH_00125 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
APGMFHAH_00126 4.64e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
APGMFHAH_00127 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
APGMFHAH_00128 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
APGMFHAH_00129 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
APGMFHAH_00130 2.06e-190 yqfA - - S - - - UPF0365 protein
APGMFHAH_00131 4.5e-56 yqfB - - - - - - -
APGMFHAH_00132 2.07e-60 yqfC - - S - - - sporulation protein YqfC
APGMFHAH_00133 6e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
APGMFHAH_00134 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
APGMFHAH_00136 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
APGMFHAH_00137 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
APGMFHAH_00138 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
APGMFHAH_00139 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
APGMFHAH_00140 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APGMFHAH_00141 5.29e-27 - - - S - - - YqzL-like protein
APGMFHAH_00142 7.48e-187 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
APGMFHAH_00143 3.01e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
APGMFHAH_00144 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
APGMFHAH_00145 3.29e-144 ccpN - - K - - - CBS domain
APGMFHAH_00146 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
APGMFHAH_00147 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
APGMFHAH_00148 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
APGMFHAH_00149 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
APGMFHAH_00150 2.29e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
APGMFHAH_00151 5.67e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
APGMFHAH_00152 2.44e-265 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APGMFHAH_00153 1.75e-226 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APGMFHAH_00154 3.73e-46 yqfQ - - S - - - YqfQ-like protein
APGMFHAH_00155 1.28e-309 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
APGMFHAH_00156 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
APGMFHAH_00157 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
APGMFHAH_00158 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
APGMFHAH_00159 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
APGMFHAH_00160 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
APGMFHAH_00161 2.04e-81 yqfX - - S - - - membrane
APGMFHAH_00162 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
APGMFHAH_00163 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
APGMFHAH_00164 2.74e-168 yqgB - - S - - - Protein of unknown function (DUF1189)
APGMFHAH_00165 1.17e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
APGMFHAH_00166 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
APGMFHAH_00167 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
APGMFHAH_00168 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
APGMFHAH_00169 5.34e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
APGMFHAH_00170 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
APGMFHAH_00171 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
APGMFHAH_00172 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APGMFHAH_00173 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
APGMFHAH_00174 1.09e-93 yqzC - - S - - - YceG-like family
APGMFHAH_00175 2.81e-67 yqzD - - - - - - -
APGMFHAH_00177 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
APGMFHAH_00178 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
APGMFHAH_00179 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APGMFHAH_00180 3.38e-14 yqgO - - - - - - -
APGMFHAH_00181 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
APGMFHAH_00182 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
APGMFHAH_00183 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
APGMFHAH_00184 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
APGMFHAH_00185 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
APGMFHAH_00186 2.69e-256 yqgU - - - - - - -
APGMFHAH_00187 7.34e-66 yqgV - - S - - - Thiamine-binding protein
APGMFHAH_00188 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
APGMFHAH_00189 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
APGMFHAH_00190 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
APGMFHAH_00191 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
APGMFHAH_00193 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APGMFHAH_00194 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
APGMFHAH_00195 8.73e-233 yqxL - - P - - - Mg2 transporter protein
APGMFHAH_00196 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
APGMFHAH_00197 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APGMFHAH_00198 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
APGMFHAH_00199 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
APGMFHAH_00200 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
APGMFHAH_00201 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
APGMFHAH_00202 1.01e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
APGMFHAH_00203 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
APGMFHAH_00204 2.84e-36 yqzE - - S - - - YqzE-like protein
APGMFHAH_00205 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
APGMFHAH_00206 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
APGMFHAH_00207 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
APGMFHAH_00208 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
APGMFHAH_00209 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
APGMFHAH_00210 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
APGMFHAH_00211 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
APGMFHAH_00212 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
APGMFHAH_00213 2.72e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
APGMFHAH_00214 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APGMFHAH_00215 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APGMFHAH_00216 7.5e-83 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
APGMFHAH_00217 8.8e-202 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
APGMFHAH_00218 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
APGMFHAH_00219 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
APGMFHAH_00220 5.18e-81 yqhP - - - - - - -
APGMFHAH_00221 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
APGMFHAH_00222 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
APGMFHAH_00223 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
APGMFHAH_00224 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
APGMFHAH_00225 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APGMFHAH_00226 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
APGMFHAH_00227 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
APGMFHAH_00228 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
APGMFHAH_00229 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
APGMFHAH_00230 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
APGMFHAH_00231 7.65e-257 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
APGMFHAH_00232 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
APGMFHAH_00233 1.08e-148 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
APGMFHAH_00234 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
APGMFHAH_00235 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
APGMFHAH_00236 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
APGMFHAH_00237 9.55e-88 yqhY - - S - - - protein conserved in bacteria
APGMFHAH_00238 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APGMFHAH_00239 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
APGMFHAH_00240 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APGMFHAH_00241 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
APGMFHAH_00242 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
APGMFHAH_00243 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
APGMFHAH_00244 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
APGMFHAH_00245 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
APGMFHAH_00246 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
APGMFHAH_00247 7.27e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
APGMFHAH_00248 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
APGMFHAH_00250 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
APGMFHAH_00252 4.74e-37 - - - - - - - -
APGMFHAH_00253 3.15e-136 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
APGMFHAH_00254 1.38e-167 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
APGMFHAH_00255 1.91e-279 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
APGMFHAH_00256 1.14e-197 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
APGMFHAH_00257 4.06e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
APGMFHAH_00258 1.85e-264 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
APGMFHAH_00259 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
APGMFHAH_00260 3.58e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
APGMFHAH_00261 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
APGMFHAH_00262 0.0 bkdR - - KT - - - Transcriptional regulator
APGMFHAH_00263 7.1e-198 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
APGMFHAH_00264 7.81e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
APGMFHAH_00265 1.18e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
APGMFHAH_00266 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APGMFHAH_00267 1.58e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APGMFHAH_00268 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APGMFHAH_00269 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APGMFHAH_00270 6.38e-195 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
APGMFHAH_00271 8.11e-222 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_00272 5.76e-212 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APGMFHAH_00273 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
APGMFHAH_00274 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
APGMFHAH_00275 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
APGMFHAH_00276 6.49e-69 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
APGMFHAH_00277 2.47e-53 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
APGMFHAH_00278 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
APGMFHAH_00279 9.84e-128 yqjB - - S - - - protein conserved in bacteria
APGMFHAH_00281 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
APGMFHAH_00282 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APGMFHAH_00283 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
APGMFHAH_00284 4.5e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
APGMFHAH_00285 3.93e-183 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APGMFHAH_00286 2.51e-32 yqzJ - - - - - - -
APGMFHAH_00287 1.84e-299 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APGMFHAH_00288 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APGMFHAH_00289 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APGMFHAH_00290 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
APGMFHAH_00291 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
APGMFHAH_00292 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APGMFHAH_00293 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
APGMFHAH_00294 0.0 rocB - - E - - - arginine degradation protein
APGMFHAH_00295 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APGMFHAH_00296 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
APGMFHAH_00297 2.81e-184 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_00298 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
APGMFHAH_00299 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
APGMFHAH_00300 5.23e-93 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APGMFHAH_00302 1.68e-288 yqjV - - G - - - Major Facilitator Superfamily
APGMFHAH_00304 4.03e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APGMFHAH_00305 1.87e-65 yqiX - - S - - - YolD-like protein
APGMFHAH_00306 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
APGMFHAH_00307 1.52e-76 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
APGMFHAH_00308 3.23e-248 yqkA - - K - - - GrpB protein
APGMFHAH_00309 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
APGMFHAH_00310 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
APGMFHAH_00311 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
APGMFHAH_00312 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
APGMFHAH_00313 2.09e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
APGMFHAH_00314 6.19e-09 - - - S - - - Protein of unknown function (DUF3936)
APGMFHAH_00315 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
APGMFHAH_00316 1.45e-280 yqxK - - L - - - DNA helicase
APGMFHAH_00317 3.18e-77 ansR - - K - - - Transcriptional regulator
APGMFHAH_00318 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
APGMFHAH_00319 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
APGMFHAH_00320 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
APGMFHAH_00321 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
APGMFHAH_00322 1.47e-41 yqkK - - - - - - -
APGMFHAH_00323 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
APGMFHAH_00324 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
APGMFHAH_00325 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
APGMFHAH_00326 1.31e-212 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
APGMFHAH_00327 2.28e-292 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
APGMFHAH_00328 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
APGMFHAH_00329 3.37e-271 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
APGMFHAH_00330 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
APGMFHAH_00331 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
APGMFHAH_00332 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_00333 1.15e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
APGMFHAH_00334 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
APGMFHAH_00335 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
APGMFHAH_00336 6.02e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
APGMFHAH_00337 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
APGMFHAH_00338 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
APGMFHAH_00339 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
APGMFHAH_00340 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
APGMFHAH_00341 3.12e-192 ypuA - - S - - - Secreted protein
APGMFHAH_00342 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APGMFHAH_00343 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APGMFHAH_00346 7.89e-68 - - - M - - - ArpU family transcriptional regulator
APGMFHAH_00348 1.12e-07 - - - S - - - YopX protein
APGMFHAH_00350 1.76e-59 - - - S - - - dUTPase
APGMFHAH_00356 2.78e-08 - - - - - - - -
APGMFHAH_00359 1.76e-10 - - - - - - - -
APGMFHAH_00360 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
APGMFHAH_00361 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
APGMFHAH_00364 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
APGMFHAH_00365 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
APGMFHAH_00368 5.28e-79 - - - - - - - -
APGMFHAH_00369 4.26e-43 - - - S - - - Phage integrase family
APGMFHAH_00370 2.09e-81 - - - S - - - Phage integrase family
APGMFHAH_00372 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
APGMFHAH_00373 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
APGMFHAH_00374 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
APGMFHAH_00375 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
APGMFHAH_00376 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
APGMFHAH_00377 4.9e-48 yvzC - - K - - - transcriptional
APGMFHAH_00378 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
APGMFHAH_00379 2.69e-86 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
APGMFHAH_00380 3.85e-72 yvaP - - K - - - transcriptional
APGMFHAH_00381 3.65e-24 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_00382 1.53e-267 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_00383 1.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
APGMFHAH_00384 5.35e-217 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APGMFHAH_00385 1.27e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
APGMFHAH_00386 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APGMFHAH_00387 1.9e-121 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
APGMFHAH_00388 9.67e-137 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
APGMFHAH_00389 6.08e-222 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
APGMFHAH_00390 6.57e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
APGMFHAH_00391 5.58e-270 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
APGMFHAH_00392 6.82e-128 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
APGMFHAH_00393 2.66e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
APGMFHAH_00394 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
APGMFHAH_00395 5.38e-155 yvbI - - M - - - Membrane
APGMFHAH_00396 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
APGMFHAH_00397 1.18e-97 yvbK - - K - - - acetyltransferase
APGMFHAH_00398 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
APGMFHAH_00399 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
APGMFHAH_00400 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
APGMFHAH_00401 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
APGMFHAH_00402 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APGMFHAH_00403 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APGMFHAH_00404 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APGMFHAH_00405 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
APGMFHAH_00406 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APGMFHAH_00407 6.96e-206 yvbU - - K - - - Transcriptional regulator
APGMFHAH_00408 5.59e-198 yvbV - - EG - - - EamA-like transporter family
APGMFHAH_00409 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_00410 2.7e-187 - - - S - - - Glycosyl hydrolase
APGMFHAH_00411 8.37e-172 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APGMFHAH_00412 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
APGMFHAH_00413 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
APGMFHAH_00414 2.52e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_00415 1.27e-250 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_00416 2.48e-171 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
APGMFHAH_00417 1.99e-207 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
APGMFHAH_00418 7.25e-201 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
APGMFHAH_00419 8.39e-263 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
APGMFHAH_00420 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
APGMFHAH_00421 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
APGMFHAH_00422 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
APGMFHAH_00423 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
APGMFHAH_00424 4.62e-292 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
APGMFHAH_00425 2.33e-235 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_00426 2.79e-145 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
APGMFHAH_00427 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
APGMFHAH_00428 1.22e-306 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
APGMFHAH_00429 5.69e-44 yvfG - - S - - - YvfG protein
APGMFHAH_00430 5.09e-239 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
APGMFHAH_00431 1.5e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
APGMFHAH_00432 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
APGMFHAH_00433 2.62e-138 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APGMFHAH_00434 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APGMFHAH_00435 5.33e-243 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
APGMFHAH_00436 9.86e-262 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
APGMFHAH_00437 3.35e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
APGMFHAH_00438 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
APGMFHAH_00439 5.23e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
APGMFHAH_00440 6.94e-199 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
APGMFHAH_00441 2.49e-278 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
APGMFHAH_00442 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
APGMFHAH_00443 1.6e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
APGMFHAH_00444 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
APGMFHAH_00445 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
APGMFHAH_00446 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
APGMFHAH_00448 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
APGMFHAH_00449 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
APGMFHAH_00450 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
APGMFHAH_00451 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
APGMFHAH_00452 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
APGMFHAH_00453 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
APGMFHAH_00454 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APGMFHAH_00456 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APGMFHAH_00457 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
APGMFHAH_00458 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APGMFHAH_00459 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
APGMFHAH_00460 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
APGMFHAH_00461 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
APGMFHAH_00462 9.28e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
APGMFHAH_00463 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
APGMFHAH_00464 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APGMFHAH_00465 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
APGMFHAH_00466 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
APGMFHAH_00468 5.61e-73 ywlA - - S - - - Uncharacterised protein family (UPF0715)
APGMFHAH_00469 1.14e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
APGMFHAH_00470 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
APGMFHAH_00471 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
APGMFHAH_00472 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
APGMFHAH_00473 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APGMFHAH_00474 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
APGMFHAH_00475 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
APGMFHAH_00476 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APGMFHAH_00477 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APGMFHAH_00478 1.83e-79 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
APGMFHAH_00479 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
APGMFHAH_00480 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APGMFHAH_00481 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
APGMFHAH_00482 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
APGMFHAH_00483 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
APGMFHAH_00484 4.46e-195 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APGMFHAH_00485 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
APGMFHAH_00486 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
APGMFHAH_00487 2.92e-113 ywmA - - - - - - -
APGMFHAH_00488 4.54e-45 ywzB - - S - - - membrane
APGMFHAH_00489 6.59e-172 ywmB - - S - - - TATA-box binding
APGMFHAH_00490 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
APGMFHAH_00491 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
APGMFHAH_00492 6.09e-49 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
APGMFHAH_00493 8.56e-96 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
APGMFHAH_00494 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
APGMFHAH_00496 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
APGMFHAH_00497 2.65e-246 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APGMFHAH_00498 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
APGMFHAH_00499 3.48e-109 ywmF - - S - - - Peptidase M50
APGMFHAH_00500 2.15e-19 csbD - - K - - - CsbD-like
APGMFHAH_00501 0.000282 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
APGMFHAH_00502 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
APGMFHAH_00503 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
APGMFHAH_00504 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
APGMFHAH_00505 4.58e-85 ywnA - - K - - - Transcriptional regulator
APGMFHAH_00506 6.73e-19 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
APGMFHAH_00507 1.42e-112 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
APGMFHAH_00508 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
APGMFHAH_00509 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
APGMFHAH_00510 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APGMFHAH_00511 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
APGMFHAH_00512 6.7e-234 - - - M - - - NeuB family
APGMFHAH_00513 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
APGMFHAH_00514 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
APGMFHAH_00515 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
APGMFHAH_00516 9.05e-93 ywnJ - - S - - - VanZ like family
APGMFHAH_00517 1.72e-134 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
APGMFHAH_00518 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
APGMFHAH_00519 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
APGMFHAH_00520 7.16e-101 - - - - - - - -
APGMFHAH_00521 1.04e-133 yjgF - - Q - - - Isochorismatase family
APGMFHAH_00522 3.63e-305 ywoD - - EGP - - - Major facilitator superfamily
APGMFHAH_00523 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
APGMFHAH_00524 3.25e-309 ywoF - - P - - - Right handed beta helix region
APGMFHAH_00525 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_00526 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
APGMFHAH_00527 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
APGMFHAH_00528 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
APGMFHAH_00529 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
APGMFHAH_00530 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
APGMFHAH_00531 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
APGMFHAH_00532 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
APGMFHAH_00533 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
APGMFHAH_00534 4.66e-186 ywpD - - T - - - Histidine kinase
APGMFHAH_00535 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
APGMFHAH_00536 3.59e-88 ywpF - - S - - - YwpF-like protein
APGMFHAH_00537 2.79e-40 ywpG - - - - - - -
APGMFHAH_00538 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
APGMFHAH_00539 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
APGMFHAH_00540 1.45e-199 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
APGMFHAH_00541 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
APGMFHAH_00542 0.0 ywqB - - S - - - SWIM zinc finger
APGMFHAH_00543 3.6e-25 - - - - - - - -
APGMFHAH_00544 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
APGMFHAH_00545 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
APGMFHAH_00546 1.75e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
APGMFHAH_00547 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APGMFHAH_00548 1.3e-38 ywqG - - S - - - Domain of unknown function (DUF1963)
APGMFHAH_00549 1.45e-108 ywqG - - S - - - Domain of unknown function (DUF1963)
APGMFHAH_00551 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
APGMFHAH_00552 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
APGMFHAH_00553 2.5e-26 - - - - - - - -
APGMFHAH_00554 1.3e-23 - - - - - - - -
APGMFHAH_00555 4.93e-95 ywqJ - - S - - - Pre-toxin TG
APGMFHAH_00556 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
APGMFHAH_00558 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
APGMFHAH_00559 4.73e-209 - - - K - - - Transcriptional regulator
APGMFHAH_00560 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
APGMFHAH_00562 1.32e-230 ydbI - - S - - - AI-2E family transporter
APGMFHAH_00563 1.8e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APGMFHAH_00564 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
APGMFHAH_00565 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
APGMFHAH_00566 1.49e-252 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
APGMFHAH_00567 2.61e-196 ydbD - - P ko:K07217 - ko00000 Catalase
APGMFHAH_00568 3.66e-82 ydbC - - S - - - Domain of unknown function (DUF4937
APGMFHAH_00569 2.17e-78 ydbB - - G - - - Cupin domain
APGMFHAH_00570 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
APGMFHAH_00571 1.23e-189 ydbA - - P - - - EcsC protein family
APGMFHAH_00572 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
APGMFHAH_00573 1.67e-42 ydaS - - S - - - membrane
APGMFHAH_00574 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
APGMFHAH_00575 6.14e-53 - - - - - - - -
APGMFHAH_00577 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
APGMFHAH_00578 1.84e-34 - - - - - - - -
APGMFHAH_00580 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
APGMFHAH_00581 3.6e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
APGMFHAH_00582 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APGMFHAH_00583 1.61e-97 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
APGMFHAH_00584 3.12e-61 ydzA - - EGP - - - Domain of unknown function (DUF3817)
APGMFHAH_00585 5.35e-178 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
APGMFHAH_00586 6.13e-100 ydaG - - S - - - general stress protein
APGMFHAH_00587 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APGMFHAH_00588 6.76e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
APGMFHAH_00589 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_00590 8.25e-127 ydaC - - Q - - - Methyltransferase domain
APGMFHAH_00591 0.0 ydaB - - IQ - - - acyl-CoA ligase
APGMFHAH_00592 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
APGMFHAH_00593 3.5e-219 ycsN - - S - - - Oxidoreductase
APGMFHAH_00594 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
APGMFHAH_00595 1.81e-64 yczJ - - S - - - biosynthesis
APGMFHAH_00597 1.2e-153 ycsK - - E - - - anatomical structure formation involved in morphogenesis
APGMFHAH_00598 1.27e-169 kipR - - K - - - Transcriptional regulator
APGMFHAH_00599 1.29e-234 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
APGMFHAH_00600 2.92e-172 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
APGMFHAH_00601 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
APGMFHAH_00602 1.32e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
APGMFHAH_00603 4.46e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
APGMFHAH_00604 3.15e-176 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
APGMFHAH_00606 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
APGMFHAH_00607 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
APGMFHAH_00608 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
APGMFHAH_00610 5.86e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
APGMFHAH_00611 2.34e-263 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
APGMFHAH_00612 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
APGMFHAH_00613 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
APGMFHAH_00614 1.34e-74 - - - - - - - -
APGMFHAH_00615 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
APGMFHAH_00616 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
APGMFHAH_00617 1.34e-132 ycnI - - S - - - protein conserved in bacteria
APGMFHAH_00618 1.39e-185 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_00619 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
APGMFHAH_00620 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APGMFHAH_00621 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APGMFHAH_00622 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APGMFHAH_00623 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
APGMFHAH_00624 1.68e-60 ycnE - - S - - - Monooxygenase
APGMFHAH_00625 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
APGMFHAH_00626 5.87e-198 ycnC - - K - - - Transcriptional regulator
APGMFHAH_00627 0.0 ycnB - - EGP - - - the major facilitator superfamily
APGMFHAH_00628 1.18e-96 - - - V - - - Restriction endonuclease
APGMFHAH_00629 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
APGMFHAH_00630 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_00631 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_00632 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_00633 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
APGMFHAH_00634 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
APGMFHAH_00635 1.58e-05 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
APGMFHAH_00637 2.18e-97 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
APGMFHAH_00638 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
APGMFHAH_00639 5.43e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_00640 7.57e-278 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
APGMFHAH_00641 1.38e-154 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
APGMFHAH_00642 4.73e-247 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
APGMFHAH_00643 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
APGMFHAH_00644 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
APGMFHAH_00646 0.0 yclG - - M - - - Pectate lyase superfamily protein
APGMFHAH_00647 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
APGMFHAH_00648 6.42e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
APGMFHAH_00649 6.45e-55 yclD - - - - - - -
APGMFHAH_00650 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
APGMFHAH_00651 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
APGMFHAH_00652 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
APGMFHAH_00653 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
APGMFHAH_00654 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
APGMFHAH_00655 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
APGMFHAH_00656 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
APGMFHAH_00657 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
APGMFHAH_00658 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APGMFHAH_00659 2.03e-124 dinB2 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APGMFHAH_00660 8.09e-53 - - - - - - - -
APGMFHAH_00662 4.33e-127 - - - J - - - Acetyltransferase (GNAT) domain
APGMFHAH_00663 4.47e-123 yokK - - S - - - SMI1 / KNR4 family
APGMFHAH_00664 4.07e-53 - - - S - - - SMI1-KNR4 cell-wall
APGMFHAH_00665 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
APGMFHAH_00666 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APGMFHAH_00667 1.14e-131 yokH - - G - - - SMI1 / KNR4 family
APGMFHAH_00668 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
APGMFHAH_00669 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
APGMFHAH_00670 1.18e-171 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
APGMFHAH_00671 1.98e-178 - - - J - - - FR47-like protein
APGMFHAH_00672 7.27e-126 yobS - - K - - - Transcriptional regulator
APGMFHAH_00673 4.49e-168 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
APGMFHAH_00674 8.64e-112 - - - K - - - Bacterial transcription activator, effector binding domain
APGMFHAH_00675 2.76e-220 yobV - - K - - - WYL domain
APGMFHAH_00676 2.58e-121 yobW - - - - - - -
APGMFHAH_00677 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
APGMFHAH_00678 6.28e-114 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APGMFHAH_00679 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
APGMFHAH_00680 1.14e-86 - - - - - - - -
APGMFHAH_00681 8.68e-67 - - - - - - - -
APGMFHAH_00682 1.08e-121 yocC - - - - - - -
APGMFHAH_00683 2.62e-238 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
APGMFHAH_00684 2.81e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
APGMFHAH_00685 4.99e-252 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_00686 1.11e-133 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_00688 1.7e-167 yocH - - M - - - COG1388 FOG LysM repeat
APGMFHAH_00689 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
APGMFHAH_00690 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APGMFHAH_00691 1.79e-86 yocK - - T - - - general stress protein
APGMFHAH_00692 4.29e-70 yocL - - - - - - -
APGMFHAH_00693 6.54e-40 - - - - - - - -
APGMFHAH_00694 1.5e-111 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
APGMFHAH_00695 2.94e-55 yozN - - - - - - -
APGMFHAH_00696 1.83e-49 yocN - - - - - - -
APGMFHAH_00697 2.17e-74 yozO - - S - - - Bacterial PH domain
APGMFHAH_00698 1.91e-42 yozC - - - - - - -
APGMFHAH_00699 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
APGMFHAH_00700 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
APGMFHAH_00701 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
APGMFHAH_00702 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APGMFHAH_00703 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
APGMFHAH_00704 3.02e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
APGMFHAH_00705 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
APGMFHAH_00706 0.0 yojO - - P - - - Von Willebrand factor
APGMFHAH_00707 8.98e-206 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
APGMFHAH_00708 3.62e-142 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
APGMFHAH_00709 1.07e-266 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
APGMFHAH_00710 3.79e-292 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
APGMFHAH_00711 3.69e-142 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
APGMFHAH_00713 5.06e-314 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
APGMFHAH_00714 1.01e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APGMFHAH_00715 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
APGMFHAH_00716 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
APGMFHAH_00717 1.85e-58 - - - - - - - -
APGMFHAH_00718 1.64e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
APGMFHAH_00719 7.43e-107 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
APGMFHAH_00720 5.59e-14 - - - - - - - -
APGMFHAH_00721 1.26e-168 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
APGMFHAH_00722 7.01e-96 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
APGMFHAH_00723 3.97e-84 iolK - - S - - - tautomerase
APGMFHAH_00724 2.63e-73 yodB - - K - - - transcriptional
APGMFHAH_00725 6.44e-139 yodC - - C - - - nitroreductase
APGMFHAH_00726 3.61e-144 yahD - - S ko:K06999 - ko00000 Carboxylesterase
APGMFHAH_00727 5.38e-220 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
APGMFHAH_00728 2.36e-38 - - - S - - - Protein of unknown function (DUF3311)
APGMFHAH_00729 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APGMFHAH_00730 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
APGMFHAH_00731 3.03e-166 yodH - - Q - - - Methyltransferase
APGMFHAH_00732 4.86e-41 yodI - - - - - - -
APGMFHAH_00733 1.33e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
APGMFHAH_00734 6.86e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
APGMFHAH_00735 1.21e-11 - - - - - - - -
APGMFHAH_00736 3.35e-71 yodL - - S - - - YodL-like
APGMFHAH_00737 5.26e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
APGMFHAH_00738 5.18e-34 yozD - - S - - - YozD-like protein
APGMFHAH_00740 7.44e-159 yodN - - - - - - -
APGMFHAH_00741 3.49e-48 yozE - - S - - - Belongs to the UPF0346 family
APGMFHAH_00742 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
APGMFHAH_00743 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
APGMFHAH_00744 1.24e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
APGMFHAH_00745 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
APGMFHAH_00746 9.44e-153 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APGMFHAH_00748 3.28e-315 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APGMFHAH_00750 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
APGMFHAH_00751 5.42e-95 ywiB - - S - - - protein conserved in bacteria
APGMFHAH_00752 3.71e-12 - - - S - - - Bacteriocin subtilosin A
APGMFHAH_00753 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
APGMFHAH_00755 5.02e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
APGMFHAH_00756 1.81e-292 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
APGMFHAH_00757 3.84e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
APGMFHAH_00758 1.17e-315 - - - L - - - Peptidase, M16
APGMFHAH_00760 1.31e-303 ywhL - - CO - - - amine dehydrogenase activity
APGMFHAH_00761 1.57e-96 ywhK - - CO - - - amine dehydrogenase activity
APGMFHAH_00762 1.72e-156 ywhK - - CO - - - amine dehydrogenase activity
APGMFHAH_00763 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
APGMFHAH_00765 2.76e-65 - - - S - - - Aminoacyl-tRNA editing domain
APGMFHAH_00766 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
APGMFHAH_00767 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
APGMFHAH_00768 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
APGMFHAH_00769 2.1e-64 - - - - - - - -
APGMFHAH_00770 1.92e-123 ywhD - - S - - - YwhD family
APGMFHAH_00771 5.45e-153 ywhC - - S - - - Peptidase family M50
APGMFHAH_00772 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
APGMFHAH_00773 1.76e-94 ywhA - - K - - - Transcriptional regulator
APGMFHAH_00774 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APGMFHAH_00776 1.54e-306 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
APGMFHAH_00777 1.1e-103 yffB - - K - - - Transcriptional regulator
APGMFHAH_00778 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
APGMFHAH_00779 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
APGMFHAH_00780 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
APGMFHAH_00781 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
APGMFHAH_00782 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
APGMFHAH_00783 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
APGMFHAH_00784 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_00785 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
APGMFHAH_00786 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
APGMFHAH_00787 3.93e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
APGMFHAH_00788 3.66e-296 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
APGMFHAH_00789 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
APGMFHAH_00790 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
APGMFHAH_00791 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_00792 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
APGMFHAH_00793 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
APGMFHAH_00794 2.2e-274 ywfA - - EGP - - - -transporter
APGMFHAH_00795 4.09e-281 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
APGMFHAH_00796 1.69e-30 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
APGMFHAH_00797 0.0 rocB - - E - - - arginine degradation protein
APGMFHAH_00798 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
APGMFHAH_00799 4.26e-310 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
APGMFHAH_00800 3.7e-101 - - - - - - - -
APGMFHAH_00801 3.73e-113 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
APGMFHAH_00802 2.34e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
APGMFHAH_00803 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
APGMFHAH_00804 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
APGMFHAH_00805 5.26e-236 spsG - - M - - - Spore Coat
APGMFHAH_00806 1.23e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
APGMFHAH_00807 1.13e-270 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
APGMFHAH_00808 4.22e-210 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
APGMFHAH_00809 9.15e-285 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
APGMFHAH_00810 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
APGMFHAH_00811 1.8e-160 spsA - - M - - - Spore Coat
APGMFHAH_00812 3.7e-106 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
APGMFHAH_00813 6.67e-202 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
APGMFHAH_00814 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_00815 3.59e-161 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APGMFHAH_00816 2.49e-256 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
APGMFHAH_00817 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_00818 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APGMFHAH_00819 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
APGMFHAH_00820 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_00821 2.79e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
APGMFHAH_00822 1.1e-228 ykvZ - - K - - - Transcriptional regulator
APGMFHAH_00823 3.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
APGMFHAH_00824 3.99e-09 - - - - - - - -
APGMFHAH_00825 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
APGMFHAH_00826 1.12e-114 stoA - - CO - - - thiol-disulfide
APGMFHAH_00827 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APGMFHAH_00828 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
APGMFHAH_00829 2.6e-39 - - - - - - - -
APGMFHAH_00830 5.43e-35 ykvS - - S - - - protein conserved in bacteria
APGMFHAH_00831 5.19e-60 ykvR - - S - - - Protein of unknown function (DUF3219)
APGMFHAH_00832 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
APGMFHAH_00833 1.69e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
APGMFHAH_00834 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
APGMFHAH_00835 1.07e-159 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APGMFHAH_00836 1.94e-226 ykvI - - S - - - membrane
APGMFHAH_00837 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
APGMFHAH_00838 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
APGMFHAH_00839 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
APGMFHAH_00840 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
APGMFHAH_00841 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
APGMFHAH_00842 5.87e-74 eag - - - - - - -
APGMFHAH_00844 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
APGMFHAH_00845 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
APGMFHAH_00846 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
APGMFHAH_00847 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
APGMFHAH_00848 3.25e-293 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
APGMFHAH_00849 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
APGMFHAH_00850 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APGMFHAH_00851 7.07e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
APGMFHAH_00852 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
APGMFHAH_00854 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APGMFHAH_00855 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_00856 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
APGMFHAH_00857 4.83e-30 ykzE - - - - - - -
APGMFHAH_00859 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
APGMFHAH_00860 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
APGMFHAH_00861 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
APGMFHAH_00862 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
APGMFHAH_00863 3.83e-204 rsgI - - S - - - Anti-sigma factor N-terminus
APGMFHAH_00864 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_00865 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
APGMFHAH_00866 1.71e-143 ykoX - - S - - - membrane-associated protein
APGMFHAH_00867 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
APGMFHAH_00868 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
APGMFHAH_00869 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
APGMFHAH_00870 3.86e-237 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
APGMFHAH_00871 0.0 ykoS - - - - - - -
APGMFHAH_00872 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
APGMFHAH_00873 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
APGMFHAH_00874 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
APGMFHAH_00875 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
APGMFHAH_00876 3.04e-36 ykoL - - - - - - -
APGMFHAH_00877 1.63e-25 - - - - - - - -
APGMFHAH_00878 1.49e-70 tnrA - - K - - - transcriptional
APGMFHAH_00879 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
APGMFHAH_00881 1.45e-08 - - - - - - - -
APGMFHAH_00882 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
APGMFHAH_00883 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
APGMFHAH_00884 6.32e-309 ykoH - - T - - - Histidine kinase
APGMFHAH_00885 5.23e-160 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_00886 1.21e-142 ykoF - - S - - - YKOF-related Family
APGMFHAH_00887 1.39e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
APGMFHAH_00888 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_00889 3.12e-174 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
APGMFHAH_00890 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
APGMFHAH_00891 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_00893 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
APGMFHAH_00894 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
APGMFHAH_00895 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
APGMFHAH_00896 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APGMFHAH_00897 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
APGMFHAH_00898 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
APGMFHAH_00899 1.06e-94 ytfJ - - S - - - Sporulation protein YtfJ
APGMFHAH_00900 2.05e-149 ytfI - - S - - - Protein of unknown function (DUF2953)
APGMFHAH_00901 2.36e-111 yteJ - - S - - - RDD family
APGMFHAH_00902 4.62e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
APGMFHAH_00903 1.69e-189 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APGMFHAH_00904 0.0 ytcJ - - S - - - amidohydrolase
APGMFHAH_00905 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APGMFHAH_00906 2.12e-40 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
APGMFHAH_00907 8.89e-289 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APGMFHAH_00908 2.74e-266 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
APGMFHAH_00909 8.23e-305 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
APGMFHAH_00910 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
APGMFHAH_00911 3.73e-198 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
APGMFHAH_00912 9.83e-141 yttP - - K - - - Transcriptional regulator
APGMFHAH_00913 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
APGMFHAH_00914 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
APGMFHAH_00915 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
APGMFHAH_00917 4.36e-302 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APGMFHAH_00918 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
APGMFHAH_00919 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
APGMFHAH_00920 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
APGMFHAH_00921 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
APGMFHAH_00922 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
APGMFHAH_00923 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
APGMFHAH_00924 1.7e-234 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
APGMFHAH_00925 3.11e-249 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
APGMFHAH_00926 1.57e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
APGMFHAH_00927 2.15e-22 ytxH - - S - - - COG4980 Gas vesicle protein
APGMFHAH_00928 7.61e-26 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
APGMFHAH_00929 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
APGMFHAH_00930 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
APGMFHAH_00931 1.78e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APGMFHAH_00932 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
APGMFHAH_00933 3.17e-75 ytpP - - CO - - - Thioredoxin
APGMFHAH_00934 7.02e-103 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
APGMFHAH_00935 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
APGMFHAH_00936 6.75e-67 ytzB - - S - - - small secreted protein
APGMFHAH_00937 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
APGMFHAH_00938 3.18e-192 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
APGMFHAH_00939 7.53e-157 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
APGMFHAH_00940 9.51e-61 ytzH - - S - - - YtzH-like protein
APGMFHAH_00941 3.02e-192 ytmP - - M - - - Phosphotransferase
APGMFHAH_00942 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
APGMFHAH_00943 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
APGMFHAH_00944 4.92e-212 ytlQ - - - - - - -
APGMFHAH_00945 2.13e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
APGMFHAH_00946 3e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
APGMFHAH_00947 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
APGMFHAH_00948 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
APGMFHAH_00949 2.89e-254 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
APGMFHAH_00950 4.65e-167 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
APGMFHAH_00951 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
APGMFHAH_00952 4.13e-127 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
APGMFHAH_00953 2.88e-271 yjcL - - S - - - Protein of unknown function (DUF819)
APGMFHAH_00955 2.75e-31 int7 - - L - - - Belongs to the 'phage' integrase family
APGMFHAH_00956 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
APGMFHAH_00957 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
APGMFHAH_00959 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
APGMFHAH_00960 5.33e-85 - - - - - - - -
APGMFHAH_00961 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
APGMFHAH_00962 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
APGMFHAH_00963 7.6e-12 - - - S - - - Helix-turn-helix domain
APGMFHAH_00964 2.09e-103 - - - - - - - -
APGMFHAH_00965 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
APGMFHAH_00966 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
APGMFHAH_00967 2.45e-34 - - - K - - - Helix-turn-helix domain
APGMFHAH_00968 7.75e-09 - - - S - - - peptidoglycan catabolic process
APGMFHAH_00974 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
APGMFHAH_00975 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APGMFHAH_00976 1.8e-87 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
APGMFHAH_00978 1.92e-47 - - - - - - - -
APGMFHAH_00979 2.28e-25 - - - - - - - -
APGMFHAH_00980 2.49e-07 - - - - - - - -
APGMFHAH_00981 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
APGMFHAH_00982 2.43e-58 yjcN - - - - - - -
APGMFHAH_00983 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
APGMFHAH_00984 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_00985 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
APGMFHAH_00986 3.33e-72 yjdF3 - - S - - - Protein of unknown function (DUF2992)
APGMFHAH_00987 1.65e-119 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
APGMFHAH_00988 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
APGMFHAH_00989 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APGMFHAH_00990 7.05e-172 yoxB - - - - - - -
APGMFHAH_00991 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
APGMFHAH_00992 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_00993 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
APGMFHAH_00994 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APGMFHAH_00995 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APGMFHAH_00996 1.68e-172 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APGMFHAH_00997 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_00998 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
APGMFHAH_00999 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
APGMFHAH_01000 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
APGMFHAH_01001 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_01002 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
APGMFHAH_01003 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
APGMFHAH_01004 1.14e-124 - - - L - - - Integrase
APGMFHAH_01006 8.34e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
APGMFHAH_01007 1.14e-311 yoeA - - V - - - MATE efflux family protein
APGMFHAH_01008 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
APGMFHAH_01009 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
APGMFHAH_01010 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APGMFHAH_01011 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
APGMFHAH_01012 7.8e-49 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
APGMFHAH_01013 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
APGMFHAH_01014 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
APGMFHAH_01015 6.03e-239 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
APGMFHAH_01016 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APGMFHAH_01017 2.81e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
APGMFHAH_01018 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
APGMFHAH_01019 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
APGMFHAH_01020 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
APGMFHAH_01021 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
APGMFHAH_01022 1.23e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
APGMFHAH_01023 2.01e-134 yngC - - S - - - membrane-associated protein
APGMFHAH_01024 4.54e-209 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
APGMFHAH_01025 1.72e-103 yngA - - S - - - membrane
APGMFHAH_01026 5.64e-35 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
APGMFHAH_01027 1.4e-301 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
APGMFHAH_01028 8.74e-93 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
APGMFHAH_01029 7.49e-90 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
APGMFHAH_01031 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
APGMFHAH_01032 4.68e-250 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
APGMFHAH_01033 5.47e-46 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
APGMFHAH_01034 8.74e-75 ynfC - - - - - - -
APGMFHAH_01035 1.82e-18 - - - - - - - -
APGMFHAH_01036 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APGMFHAH_01037 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
APGMFHAH_01038 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
APGMFHAH_01039 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
APGMFHAH_01040 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
APGMFHAH_01041 3.3e-71 yneQ - - - - - - -
APGMFHAH_01042 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
APGMFHAH_01043 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
APGMFHAH_01045 9.26e-10 - - - S - - - Fur-regulated basic protein B
APGMFHAH_01046 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APGMFHAH_01047 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APGMFHAH_01048 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
APGMFHAH_01049 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
APGMFHAH_01050 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
APGMFHAH_01051 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
APGMFHAH_01052 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
APGMFHAH_01053 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
APGMFHAH_01054 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
APGMFHAH_01055 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
APGMFHAH_01056 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
APGMFHAH_01057 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
APGMFHAH_01058 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APGMFHAH_01059 1.15e-43 ynzC - - S - - - UPF0291 protein
APGMFHAH_01060 5.4e-143 yneB - - L - - - resolvase
APGMFHAH_01061 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
APGMFHAH_01062 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
APGMFHAH_01063 8.86e-96 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
APGMFHAH_01064 1.54e-95 yndM - - S - - - Protein of unknown function (DUF2512)
APGMFHAH_01065 2.68e-174 yndL - - S - - - Replication protein
APGMFHAH_01067 0.0 yndJ - - S - - - YndJ-like protein
APGMFHAH_01068 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
APGMFHAH_01069 2.52e-196 yndG - - S - - - DoxX-like family
APGMFHAH_01070 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
APGMFHAH_01071 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
APGMFHAH_01072 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
APGMFHAH_01075 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
APGMFHAH_01076 8.92e-96 - - - - - - - -
APGMFHAH_01077 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
APGMFHAH_01080 2.43e-162 - - - S - - - Domain of unknown function, YrpD
APGMFHAH_01082 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
APGMFHAH_01085 7.54e-22 - - - - - - - -
APGMFHAH_01086 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
APGMFHAH_01088 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APGMFHAH_01089 3.48e-311 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APGMFHAH_01090 9.79e-143 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
APGMFHAH_01091 0.0 wapA - - M - - - COG3209 Rhs family protein
APGMFHAH_01092 1.09e-94 yxxG - - - - - - -
APGMFHAH_01093 5.25e-111 - - - - - - - -
APGMFHAH_01094 1.12e-82 - - - - - - - -
APGMFHAH_01095 8.76e-99 yxiG - - - - - - -
APGMFHAH_01096 1.85e-177 - - - - - - - -
APGMFHAH_01097 4.99e-121 yxiI - - S - - - Protein of unknown function (DUF2716)
APGMFHAH_01098 1.86e-40 - - - - - - - -
APGMFHAH_01101 1.94e-56 yxiJ - - S - - - YxiJ-like protein
APGMFHAH_01104 8.65e-275 - - - E - - - GDSL-like Lipase/Acylhydrolase
APGMFHAH_01105 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
APGMFHAH_01106 1.8e-290 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
APGMFHAH_01107 2.16e-142 - - - - - - - -
APGMFHAH_01108 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
APGMFHAH_01109 7.21e-183 bglS - - M - - - licheninase activity
APGMFHAH_01110 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
APGMFHAH_01111 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
APGMFHAH_01112 6.3e-61 yxiS - - - - - - -
APGMFHAH_01113 9.87e-132 - - - T - - - Domain of unknown function (DUF4163)
APGMFHAH_01114 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APGMFHAH_01115 2.42e-201 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
APGMFHAH_01116 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
APGMFHAH_01117 9.99e-66 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APGMFHAH_01118 7.21e-60 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APGMFHAH_01119 1.69e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
APGMFHAH_01120 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
APGMFHAH_01121 2.21e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
APGMFHAH_01122 5.01e-276 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
APGMFHAH_01123 2.88e-111 yxjI - - S - - - LURP-one-related
APGMFHAH_01126 1.06e-296 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
APGMFHAH_01127 2.69e-148 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
APGMFHAH_01128 1.25e-242 - - - T - - - Signal transduction histidine kinase
APGMFHAH_01129 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
APGMFHAH_01130 1.74e-250 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
APGMFHAH_01131 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
APGMFHAH_01132 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APGMFHAH_01133 1.3e-208 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
APGMFHAH_01134 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_01135 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
APGMFHAH_01137 0.0 - - - O - - - Peptidase family M48
APGMFHAH_01138 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
APGMFHAH_01139 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
APGMFHAH_01140 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
APGMFHAH_01141 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
APGMFHAH_01142 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
APGMFHAH_01143 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
APGMFHAH_01144 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
APGMFHAH_01145 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
APGMFHAH_01146 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APGMFHAH_01147 1.49e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
APGMFHAH_01148 3.27e-192 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APGMFHAH_01149 7.17e-99 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
APGMFHAH_01150 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
APGMFHAH_01151 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
APGMFHAH_01152 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
APGMFHAH_01153 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APGMFHAH_01154 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
APGMFHAH_01155 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
APGMFHAH_01156 2.13e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
APGMFHAH_01157 6.35e-113 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
APGMFHAH_01158 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APGMFHAH_01159 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
APGMFHAH_01160 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
APGMFHAH_01161 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
APGMFHAH_01162 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APGMFHAH_01163 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
APGMFHAH_01164 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
APGMFHAH_01165 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
APGMFHAH_01166 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
APGMFHAH_01167 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APGMFHAH_01168 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
APGMFHAH_01169 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APGMFHAH_01170 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
APGMFHAH_01171 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
APGMFHAH_01172 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APGMFHAH_01173 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APGMFHAH_01174 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
APGMFHAH_01175 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
APGMFHAH_01176 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
APGMFHAH_01177 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APGMFHAH_01178 2.01e-287 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
APGMFHAH_01179 7.13e-228 ybaC - - S - - - Alpha/beta hydrolase family
APGMFHAH_01180 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
APGMFHAH_01181 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
APGMFHAH_01182 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
APGMFHAH_01183 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
APGMFHAH_01184 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APGMFHAH_01185 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
APGMFHAH_01186 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APGMFHAH_01187 6.89e-151 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
APGMFHAH_01188 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
APGMFHAH_01189 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
APGMFHAH_01190 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
APGMFHAH_01191 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
APGMFHAH_01192 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
APGMFHAH_01193 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APGMFHAH_01194 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
APGMFHAH_01195 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
APGMFHAH_01196 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
APGMFHAH_01197 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
APGMFHAH_01198 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
APGMFHAH_01199 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
APGMFHAH_01200 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
APGMFHAH_01201 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
APGMFHAH_01202 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
APGMFHAH_01203 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
APGMFHAH_01204 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APGMFHAH_01205 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
APGMFHAH_01206 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APGMFHAH_01207 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APGMFHAH_01208 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
APGMFHAH_01209 1.01e-75 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
APGMFHAH_01210 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APGMFHAH_01211 1.1e-196 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APGMFHAH_01212 1.6e-177 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
APGMFHAH_01213 1.51e-182 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
APGMFHAH_01214 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
APGMFHAH_01215 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
APGMFHAH_01216 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
APGMFHAH_01217 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
APGMFHAH_01218 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
APGMFHAH_01219 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
APGMFHAH_01220 1.04e-122 gerD - - - ko:K06294 - ko00000 -
APGMFHAH_01221 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
APGMFHAH_01222 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
APGMFHAH_01223 1.16e-101 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APGMFHAH_01224 9.39e-63 yhcM - - - - - - -
APGMFHAH_01226 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
APGMFHAH_01227 1.42e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
APGMFHAH_01230 3.73e-240 yppC - - S - - - Protein of unknown function (DUF2515)
APGMFHAH_01231 3.2e-150 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
APGMFHAH_01232 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
APGMFHAH_01233 5.81e-121 ypoC - - - - - - -
APGMFHAH_01234 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APGMFHAH_01235 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
APGMFHAH_01236 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
APGMFHAH_01237 7.24e-284 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
APGMFHAH_01238 2.27e-103 ypmB - - S - - - protein conserved in bacteria
APGMFHAH_01239 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
APGMFHAH_01240 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
APGMFHAH_01241 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
APGMFHAH_01242 5.47e-200 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
APGMFHAH_01243 4.85e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
APGMFHAH_01244 4.87e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
APGMFHAH_01245 2.5e-277 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APGMFHAH_01246 2.34e-265 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
APGMFHAH_01247 7.71e-166 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
APGMFHAH_01248 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
APGMFHAH_01249 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
APGMFHAH_01250 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
APGMFHAH_01251 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
APGMFHAH_01252 6.56e-181 ypjB - - S - - - sporulation protein
APGMFHAH_01253 1.15e-125 ypjA - - S - - - membrane
APGMFHAH_01254 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
APGMFHAH_01255 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
APGMFHAH_01256 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
APGMFHAH_01257 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
APGMFHAH_01258 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
APGMFHAH_01259 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
APGMFHAH_01260 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
APGMFHAH_01261 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
APGMFHAH_01262 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
APGMFHAH_01263 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
APGMFHAH_01264 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
APGMFHAH_01265 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
APGMFHAH_01266 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
APGMFHAH_01267 6.08e-230 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
APGMFHAH_01268 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APGMFHAH_01269 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
APGMFHAH_01270 3.86e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
APGMFHAH_01271 1.44e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
APGMFHAH_01272 1.5e-182 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
APGMFHAH_01273 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
APGMFHAH_01274 5.81e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
APGMFHAH_01275 1.1e-168 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
APGMFHAH_01276 8.72e-178 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
APGMFHAH_01277 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
APGMFHAH_01278 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
APGMFHAH_01279 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
APGMFHAH_01280 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
APGMFHAH_01281 8.71e-176 yphF - - - - - - -
APGMFHAH_01282 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
APGMFHAH_01283 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
APGMFHAH_01284 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
APGMFHAH_01285 2.06e-38 ypzH - - - - - - -
APGMFHAH_01286 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
APGMFHAH_01287 2.73e-134 yphA - - - - - - -
APGMFHAH_01288 1.13e-11 - - - S - - - YpzI-like protein
APGMFHAH_01289 4.66e-235 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
APGMFHAH_01290 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
APGMFHAH_01291 2.36e-145 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
APGMFHAH_01292 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
APGMFHAH_01293 2.2e-142 ypfA - - M - - - Flagellar protein YcgR
APGMFHAH_01294 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
APGMFHAH_01295 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
APGMFHAH_01296 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
APGMFHAH_01297 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
APGMFHAH_01298 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
APGMFHAH_01299 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APGMFHAH_01300 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
APGMFHAH_01301 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
APGMFHAH_01302 5.04e-148 ypbE - - M - - - Lysin motif
APGMFHAH_01303 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
APGMFHAH_01304 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
APGMFHAH_01305 1.28e-254 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
APGMFHAH_01306 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
APGMFHAH_01307 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
APGMFHAH_01308 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APGMFHAH_01309 1.32e-171 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
APGMFHAH_01310 1.15e-244 rsiX - - - - - - -
APGMFHAH_01311 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_01312 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_01313 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_01314 6.36e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
APGMFHAH_01315 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
APGMFHAH_01316 1.5e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
APGMFHAH_01317 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
APGMFHAH_01318 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
APGMFHAH_01319 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
APGMFHAH_01320 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
APGMFHAH_01321 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
APGMFHAH_01322 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
APGMFHAH_01323 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
APGMFHAH_01324 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
APGMFHAH_01325 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APGMFHAH_01326 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
APGMFHAH_01327 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APGMFHAH_01328 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
APGMFHAH_01329 2.07e-260 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APGMFHAH_01330 5.98e-72 ypuD - - - - - - -
APGMFHAH_01331 1.67e-125 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
APGMFHAH_01332 1.75e-43 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
APGMFHAH_01334 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APGMFHAH_01336 3.82e-37 - - - - - - - -
APGMFHAH_01337 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
APGMFHAH_01339 3.96e-84 - - - O - - - Papain family cysteine protease
APGMFHAH_01340 1.73e-13 - - - - - - - -
APGMFHAH_01341 4.32e-232 yaaC - - S - - - YaaC-like Protein
APGMFHAH_01342 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
APGMFHAH_01343 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
APGMFHAH_01344 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
APGMFHAH_01345 9.58e-138 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
APGMFHAH_01346 9.79e-296 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
APGMFHAH_01348 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
APGMFHAH_01349 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
APGMFHAH_01350 2.74e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
APGMFHAH_01351 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
APGMFHAH_01352 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
APGMFHAH_01353 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APGMFHAH_01354 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
APGMFHAH_01355 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APGMFHAH_01356 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
APGMFHAH_01357 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
APGMFHAH_01358 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APGMFHAH_01359 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APGMFHAH_01360 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
APGMFHAH_01361 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
APGMFHAH_01362 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
APGMFHAH_01363 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
APGMFHAH_01364 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
APGMFHAH_01365 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
APGMFHAH_01366 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APGMFHAH_01367 1.83e-141 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
APGMFHAH_01368 9.06e-317 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
APGMFHAH_01369 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
APGMFHAH_01370 1.01e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
APGMFHAH_01371 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
APGMFHAH_01372 3.77e-97 - - - S - - - Bacterial PH domain
APGMFHAH_01373 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
APGMFHAH_01374 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
APGMFHAH_01375 1.3e-144 yyaC - - S - - - Sporulation protein YyaC
APGMFHAH_01376 5.34e-227 yyaD - - S - - - Membrane
APGMFHAH_01377 7.41e-45 yyzM - - S - - - protein conserved in bacteria
APGMFHAH_01378 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APGMFHAH_01379 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
APGMFHAH_01380 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
APGMFHAH_01381 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
APGMFHAH_01382 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
APGMFHAH_01383 1.14e-67 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
APGMFHAH_01384 1.75e-92 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
APGMFHAH_01385 1.44e-228 ccpB - - K - - - Transcriptional regulator
APGMFHAH_01386 7.2e-90 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APGMFHAH_01387 1.33e-129 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
APGMFHAH_01388 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
APGMFHAH_01389 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
APGMFHAH_01390 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
APGMFHAH_01391 3.27e-257 tetL - - EGP ko:K08168 - ko00000,ko00002,ko01504,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_01392 1.57e-128 yyaP - - H - - - RibD C-terminal domain
APGMFHAH_01393 1.5e-85 - - - S - - - YjbR
APGMFHAH_01394 4.7e-120 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
APGMFHAH_01395 8.63e-125 yyaS - - S ko:K07149 - ko00000 Membrane
APGMFHAH_01396 4.18e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
APGMFHAH_01397 4.54e-100 yybA - - K - - - transcriptional
APGMFHAH_01398 2.04e-88 - - - S - - - Metallo-beta-lactamase superfamily
APGMFHAH_01399 6.02e-127 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_01400 2.81e-162 yybG - - S - - - Pentapeptide repeat-containing protein
APGMFHAH_01401 2.39e-85 - - - S - - - SnoaL-like domain
APGMFHAH_01402 2.91e-183 - - - - - - - -
APGMFHAH_01403 1.51e-121 - - - K - - - TipAS antibiotic-recognition domain
APGMFHAH_01404 1.01e-307 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_01406 3.19e-90 - - - - - - - -
APGMFHAH_01407 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
APGMFHAH_01408 1.3e-87 yybR - - K - - - Transcriptional regulator
APGMFHAH_01409 2.89e-110 cotF - - M ko:K06329 - ko00000 Spore coat protein
APGMFHAH_01411 1.5e-204 yybS - - S - - - membrane
APGMFHAH_01412 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
APGMFHAH_01413 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
APGMFHAH_01414 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APGMFHAH_01415 3.17e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
APGMFHAH_01416 1.89e-22 yycC - - K - - - YycC-like protein
APGMFHAH_01418 2.87e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
APGMFHAH_01419 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
APGMFHAH_01420 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APGMFHAH_01421 3.02e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APGMFHAH_01426 1.45e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_01427 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_01428 0.0 yycH - - S - - - protein conserved in bacteria
APGMFHAH_01429 3.44e-200 yycI - - S - - - protein conserved in bacteria
APGMFHAH_01430 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
APGMFHAH_01431 9.43e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APGMFHAH_01432 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
APGMFHAH_01433 2.31e-54 sdpR - - K - - - transcriptional
APGMFHAH_01434 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
APGMFHAH_01435 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
APGMFHAH_01436 4.85e-119 - - - - - - - -
APGMFHAH_01437 5.82e-20 - - - - - - - -
APGMFHAH_01438 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
APGMFHAH_01439 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
APGMFHAH_01440 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
APGMFHAH_01442 2.06e-204 - - - S - - - aspartate phosphatase
APGMFHAH_01443 1.17e-18 - - - S - - - aspartate phosphatase
APGMFHAH_01444 3.44e-108 yycN - - K - - - Acetyltransferase
APGMFHAH_01445 7.97e-168 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
APGMFHAH_01446 1.61e-256 yycP - - - - - - -
APGMFHAH_01447 1.58e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
APGMFHAH_01449 8.21e-67 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APGMFHAH_01450 1.43e-54 - - - S - - - LlaJI restriction endonuclease
APGMFHAH_01451 6.97e-115 - - - V - - - AAA domain (dynein-related subfamily)
APGMFHAH_01452 3.24e-203 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
APGMFHAH_01453 3.2e-186 - 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 C-5 cytosine-specific DNA methylase
APGMFHAH_01455 2.89e-105 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
APGMFHAH_01456 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
APGMFHAH_01457 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
APGMFHAH_01458 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
APGMFHAH_01459 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_01460 1.15e-37 - 2.7.1.199 - G ko:K02777,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 phosphoenolpyruvate-dependent sugar phosphotransferase system
APGMFHAH_01461 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
APGMFHAH_01462 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
APGMFHAH_01463 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
APGMFHAH_01464 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APGMFHAH_01465 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
APGMFHAH_01466 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
APGMFHAH_01467 1.27e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
APGMFHAH_01468 3.46e-265 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
APGMFHAH_01469 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
APGMFHAH_01470 2.19e-153 yxaC - - M - - - effector of murein hydrolase
APGMFHAH_01471 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
APGMFHAH_01472 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
APGMFHAH_01473 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_01474 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
APGMFHAH_01475 5.18e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
APGMFHAH_01476 1.46e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
APGMFHAH_01477 1.35e-97 yxaI - - S - - - membrane protein domain
APGMFHAH_01478 7.97e-83 - - - S - - - Family of unknown function (DUF5391)
APGMFHAH_01479 2.54e-43 yxaI - - S - - - membrane protein domain
APGMFHAH_01480 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
APGMFHAH_01481 6.97e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
APGMFHAH_01482 2.81e-191 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
APGMFHAH_01484 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
APGMFHAH_01485 6.88e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APGMFHAH_01486 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APGMFHAH_01487 4.47e-103 - - - T - - - HPP family
APGMFHAH_01488 2.23e-17 - - - S - - - CGNR zinc finger
APGMFHAH_01490 7.27e-55 - - - - - - - -
APGMFHAH_01491 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
APGMFHAH_01492 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
APGMFHAH_01493 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APGMFHAH_01494 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
APGMFHAH_01495 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
APGMFHAH_01496 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
APGMFHAH_01497 8.63e-223 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
APGMFHAH_01498 1.46e-102 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
APGMFHAH_01499 2.23e-173 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
APGMFHAH_01500 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
APGMFHAH_01501 4.4e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
APGMFHAH_01502 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
APGMFHAH_01503 4.69e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
APGMFHAH_01504 2.8e-160 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_01505 7.41e-229 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_01506 6.59e-67 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_01507 5.08e-90 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_01508 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
APGMFHAH_01509 3.45e-76 yxeA - - S - - - Protein of unknown function (DUF1093)
APGMFHAH_01510 1.27e-214 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
APGMFHAH_01511 6.79e-91 - - - - - - - -
APGMFHAH_01512 7.57e-28 yxeD - - - - - - -
APGMFHAH_01513 5.99e-41 yxeE - - - - - - -
APGMFHAH_01516 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
APGMFHAH_01517 1.64e-238 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
APGMFHAH_01518 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APGMFHAH_01519 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APGMFHAH_01520 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
APGMFHAH_01521 6.05e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
APGMFHAH_01522 1.13e-169 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_01523 2.89e-272 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
APGMFHAH_01524 1.87e-316 yxeQ - - S - - - MmgE/PrpD family
APGMFHAH_01525 1.49e-253 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
APGMFHAH_01526 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
APGMFHAH_01527 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
APGMFHAH_01528 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
APGMFHAH_01529 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APGMFHAH_01530 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
APGMFHAH_01531 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
APGMFHAH_01532 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
APGMFHAH_01533 2.55e-306 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
APGMFHAH_01534 4.71e-108 - - - L - - - HaeIII restriction endonuclease
APGMFHAH_01535 1.65e-186 ddeI 2.1.1.37 - L ko:K00558 ko00270,ko01100,ko05206,map00270,map01100,map05206 ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036 DNA (cytosine-5-)-methyltransferase activity
APGMFHAH_01536 8.25e-58 - - - L ko:K07458 - ko00000,ko01000,ko03400 May nick specific sequences that contain T G mispairs resulting from m5C-deamination
APGMFHAH_01538 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
APGMFHAH_01539 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
APGMFHAH_01540 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
APGMFHAH_01541 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
APGMFHAH_01542 1.56e-53 - - - - - - - -
APGMFHAH_01543 1.99e-82 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
APGMFHAH_01544 3.07e-216 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
APGMFHAH_01545 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
APGMFHAH_01546 1.52e-155 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
APGMFHAH_01547 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_01548 5.69e-208 yxxF - - EG - - - EamA-like transporter family
APGMFHAH_01550 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
APGMFHAH_01551 4.59e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APGMFHAH_01552 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
APGMFHAH_01553 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
APGMFHAH_01554 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
APGMFHAH_01555 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
APGMFHAH_01556 2.43e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APGMFHAH_01557 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
APGMFHAH_01558 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
APGMFHAH_01559 9.93e-15 - - - - - - - -
APGMFHAH_01560 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APGMFHAH_01561 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
APGMFHAH_01562 9.79e-102 ykgA - - E - - - Amidinotransferase
APGMFHAH_01563 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
APGMFHAH_01564 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_01565 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APGMFHAH_01566 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
APGMFHAH_01567 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
APGMFHAH_01569 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
APGMFHAH_01570 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_01571 1.23e-223 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APGMFHAH_01572 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APGMFHAH_01573 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
APGMFHAH_01574 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
APGMFHAH_01575 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APGMFHAH_01577 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
APGMFHAH_01578 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APGMFHAH_01579 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
APGMFHAH_01580 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
APGMFHAH_01581 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
APGMFHAH_01582 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
APGMFHAH_01583 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
APGMFHAH_01584 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
APGMFHAH_01585 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
APGMFHAH_01586 5.5e-51 xhlB - - S - - - SPP1 phage holin
APGMFHAH_01587 2.21e-51 xhlA - - S - - - Haemolysin XhlA
APGMFHAH_01588 9.79e-195 xepA - - - - - - -
APGMFHAH_01589 6.35e-31 xkdX - - - - - - -
APGMFHAH_01590 2.7e-68 xkdW - - S - - - XkdW protein
APGMFHAH_01591 0.0 - - - - - - - -
APGMFHAH_01592 4.43e-56 - - - - - - - -
APGMFHAH_01593 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
APGMFHAH_01594 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
APGMFHAH_01595 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
APGMFHAH_01596 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
APGMFHAH_01597 2.31e-232 xkdQ - - G - - - NLP P60 protein
APGMFHAH_01598 1.73e-151 xkdP - - S - - - Lysin motif
APGMFHAH_01599 0.0 xkdO - - L - - - Transglycosylase SLT domain
APGMFHAH_01600 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
APGMFHAH_01601 6.01e-99 xkdM - - S - - - Phage tail tube protein
APGMFHAH_01602 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
APGMFHAH_01603 2.87e-101 xkdJ - - - - - - -
APGMFHAH_01604 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
APGMFHAH_01605 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
APGMFHAH_01606 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
APGMFHAH_01607 3.91e-217 xkdG - - S - - - Phage capsid family
APGMFHAH_01608 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
APGMFHAH_01609 0.0 yqbA - - S - - - portal protein
APGMFHAH_01610 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
APGMFHAH_01611 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
APGMFHAH_01612 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
APGMFHAH_01617 8.72e-152 xkdC - - L - - - Bacterial dnaA protein
APGMFHAH_01618 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
APGMFHAH_01620 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
APGMFHAH_01621 1.79e-143 xkdA - - E - - - IrrE N-terminal-like domain
APGMFHAH_01622 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
APGMFHAH_01623 1.11e-138 yjqB - - S - - - Pfam:DUF867
APGMFHAH_01624 1.35e-80 yjqA - - S - - - Bacterial PH domain
APGMFHAH_01625 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
APGMFHAH_01626 1.09e-34 - - - S - - - YCII-related domain
APGMFHAH_01628 4.48e-22 lytR - - K - - - May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
APGMFHAH_01629 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
APGMFHAH_01630 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APGMFHAH_01631 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
APGMFHAH_01632 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APGMFHAH_01634 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
APGMFHAH_01635 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
APGMFHAH_01636 1.33e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
APGMFHAH_01637 7.15e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
APGMFHAH_01638 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
APGMFHAH_01640 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_01643 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
APGMFHAH_01646 2.3e-158 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
APGMFHAH_01647 2.17e-224 pbpE - - V - - - Beta-lactamase
APGMFHAH_01648 3.77e-79 pbpE - - V - - - Beta-lactamase
APGMFHAH_01649 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
APGMFHAH_01650 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
APGMFHAH_01651 0.0 ybeC - - E - - - amino acid
APGMFHAH_01652 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
APGMFHAH_01653 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
APGMFHAH_01654 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
APGMFHAH_01655 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
APGMFHAH_01657 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
APGMFHAH_01658 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
APGMFHAH_01659 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
APGMFHAH_01660 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
APGMFHAH_01661 3.55e-200 malA - - S - - - Protein of unknown function (DUF1189)
APGMFHAH_01662 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
APGMFHAH_01663 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
APGMFHAH_01664 2.83e-300 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
APGMFHAH_01665 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
APGMFHAH_01666 6.55e-223 yvdE - - K - - - Transcriptional regulator
APGMFHAH_01667 2.66e-137 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
APGMFHAH_01668 1.27e-39 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
APGMFHAH_01669 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
APGMFHAH_01670 1.07e-136 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
APGMFHAH_01671 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APGMFHAH_01672 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
APGMFHAH_01673 3.67e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_01674 2.78e-251 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
APGMFHAH_01675 1.9e-171 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_01676 2.3e-182 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
APGMFHAH_01677 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
APGMFHAH_01678 3.63e-220 whiA - - K ko:K09762 - ko00000 May be required for sporulation
APGMFHAH_01679 6.72e-227 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
APGMFHAH_01680 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
APGMFHAH_01681 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
APGMFHAH_01682 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
APGMFHAH_01683 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
APGMFHAH_01684 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
APGMFHAH_01685 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
APGMFHAH_01687 2.62e-314 - - - - - - - -
APGMFHAH_01688 9.72e-104 - - - - - - - -
APGMFHAH_01689 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
APGMFHAH_01690 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
APGMFHAH_01691 1.88e-166 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APGMFHAH_01692 1.2e-148 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APGMFHAH_01693 2.87e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
APGMFHAH_01694 4.08e-289 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APGMFHAH_01695 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
APGMFHAH_01696 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
APGMFHAH_01697 5.03e-178 yvpB - - NU - - - protein conserved in bacteria
APGMFHAH_01698 1.63e-155 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
APGMFHAH_01699 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
APGMFHAH_01700 1.06e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
APGMFHAH_01701 3.72e-211 yvoD - - P - - - COG0370 Fe2 transport system protein B
APGMFHAH_01702 9.11e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
APGMFHAH_01703 8.52e-216 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
APGMFHAH_01704 2.51e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
APGMFHAH_01705 3.01e-166 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APGMFHAH_01706 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
APGMFHAH_01707 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
APGMFHAH_01708 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
APGMFHAH_01709 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
APGMFHAH_01710 5.8e-221 yvlB - - S - - - Putative adhesin
APGMFHAH_01711 8.09e-65 yvlA - - - - - - -
APGMFHAH_01712 2.25e-45 yvkN - - - - - - -
APGMFHAH_01713 1.68e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APGMFHAH_01714 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
APGMFHAH_01715 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
APGMFHAH_01716 2.54e-42 csbA - - S - - - protein conserved in bacteria
APGMFHAH_01717 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
APGMFHAH_01718 2.76e-129 yvkB - - K - - - Transcriptional regulator
APGMFHAH_01719 3.03e-295 yvkA - - P - - - -transporter
APGMFHAH_01720 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APGMFHAH_01721 1.38e-73 swrA - - S - - - Swarming motility protein
APGMFHAH_01722 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
APGMFHAH_01723 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
APGMFHAH_01724 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
APGMFHAH_01725 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
APGMFHAH_01726 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
APGMFHAH_01727 2e-232 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
APGMFHAH_01728 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
APGMFHAH_01729 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APGMFHAH_01730 2.46e-67 - - - - - - - -
APGMFHAH_01731 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
APGMFHAH_01732 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
APGMFHAH_01733 2.21e-313 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APGMFHAH_01734 9.77e-71 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
APGMFHAH_01735 6.11e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APGMFHAH_01736 4.29e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
APGMFHAH_01737 7.11e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
APGMFHAH_01738 2.81e-91 yviE - - - - - - -
APGMFHAH_01739 3.8e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
APGMFHAH_01740 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
APGMFHAH_01741 3.5e-102 yvyG - - NOU - - - FlgN protein
APGMFHAH_01742 5.05e-52 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
APGMFHAH_01743 6.15e-95 yvyF - - S - - - flagellar protein
APGMFHAH_01744 8.46e-158 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
APGMFHAH_01745 2.06e-43 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
APGMFHAH_01746 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
APGMFHAH_01747 5.06e-198 degV - - S - - - protein conserved in bacteria
APGMFHAH_01748 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_01749 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
APGMFHAH_01750 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
APGMFHAH_01751 1.23e-151 - - - K - - - Transcriptional regulator
APGMFHAH_01752 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
APGMFHAH_01753 1.28e-139 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_01754 4.58e-250 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_01756 1.12e-103 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APGMFHAH_01757 1.23e-157 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
APGMFHAH_01758 4.04e-149 ydfE - - S - - - Flavin reductase like domain
APGMFHAH_01759 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
APGMFHAH_01760 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APGMFHAH_01761 9.99e-197 - - - EG - - - EamA-like transporter family
APGMFHAH_01762 8.66e-186 - - - J - - - GNAT acetyltransferase
APGMFHAH_01763 3.38e-292 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APGMFHAH_01764 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
APGMFHAH_01765 9.32e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
APGMFHAH_01766 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
APGMFHAH_01767 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
APGMFHAH_01768 1.04e-69 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
APGMFHAH_01769 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APGMFHAH_01770 4.66e-197 ydeK - - EG - - - -transporter
APGMFHAH_01771 3.47e-110 - - - K - - - Transcriptional regulator C-terminal region
APGMFHAH_01772 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
APGMFHAH_01773 2.4e-41 - - - S - - - SNARE associated Golgi protein
APGMFHAH_01774 1.27e-142 - - - - - - - -
APGMFHAH_01775 9.12e-36 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
APGMFHAH_01776 3.21e-70 ydeH - - - - - - -
APGMFHAH_01777 1.16e-234 ydeG - - EGP - - - Major facilitator superfamily
APGMFHAH_01778 3.74e-24 ydeG - - EGP - - - Major facilitator superfamily
APGMFHAH_01779 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APGMFHAH_01780 7.56e-209 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
APGMFHAH_01781 5.34e-219 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APGMFHAH_01782 2.44e-210 - - - K - - - AraC-like ligand binding domain
APGMFHAH_01783 4.54e-176 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
APGMFHAH_01785 2.14e-17 - - - Q - - - methyltransferase
APGMFHAH_01786 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
APGMFHAH_01787 0.000751 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
APGMFHAH_01788 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
APGMFHAH_01790 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
APGMFHAH_01792 4.46e-23 - - - - - - - -
APGMFHAH_01793 3.2e-59 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
APGMFHAH_01794 7.66e-99 - - - - - - - -
APGMFHAH_01795 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
APGMFHAH_01796 4.98e-106 yoaW - - - - - - -
APGMFHAH_01797 4.01e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
APGMFHAH_01799 1.4e-104 - - - S - - - Domain of unknown function (DUF3885)
APGMFHAH_01800 4.82e-69 ynaF - - - - - - -
APGMFHAH_01802 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
APGMFHAH_01804 0.0 - - - V - - - Beta-lactamase
APGMFHAH_01808 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
APGMFHAH_01809 5.71e-121 - - - M - - - FR47-like protein
APGMFHAH_01810 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
APGMFHAH_01811 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
APGMFHAH_01812 6.53e-108 yuaE - - S - - - DinB superfamily
APGMFHAH_01813 3.92e-135 yuaD - - - - - - -
APGMFHAH_01814 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
APGMFHAH_01815 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
APGMFHAH_01816 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
APGMFHAH_01817 5.83e-118 yuaB - - - - - - -
APGMFHAH_01818 8.71e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
APGMFHAH_01819 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
APGMFHAH_01820 3.31e-52 yubF - - S - - - yiaA/B two helix domain
APGMFHAH_01821 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APGMFHAH_01822 0.0 yubD - - P - - - Major Facilitator Superfamily
APGMFHAH_01823 3.95e-113 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
APGMFHAH_01825 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
APGMFHAH_01826 1.73e-252 yubA - - S - - - transporter activity
APGMFHAH_01827 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
APGMFHAH_01828 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
APGMFHAH_01829 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
APGMFHAH_01830 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
APGMFHAH_01831 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
APGMFHAH_01832 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
APGMFHAH_01833 1.49e-184 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_01834 8.35e-116 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_01835 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_01836 2.29e-295 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_01837 6.39e-119 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
APGMFHAH_01838 3.4e-283 yhjG - - CH - - - FAD binding domain
APGMFHAH_01839 1.21e-30 yhjG - - CH - - - FAD binding domain
APGMFHAH_01840 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
APGMFHAH_01841 4.87e-141 yhjE - - S - - - SNARE associated Golgi protein
APGMFHAH_01842 1.01e-75 yhjD - - - - - - -
APGMFHAH_01843 1.32e-35 yhjC - - S - - - Protein of unknown function (DUF3311)
APGMFHAH_01844 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APGMFHAH_01845 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
APGMFHAH_01846 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
APGMFHAH_01847 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
APGMFHAH_01848 9.84e-45 yhzC - - S - - - IDEAL
APGMFHAH_01849 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_01850 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
APGMFHAH_01851 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
APGMFHAH_01852 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
APGMFHAH_01853 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
APGMFHAH_01854 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
APGMFHAH_01855 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
APGMFHAH_01856 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
APGMFHAH_01857 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
APGMFHAH_01858 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
APGMFHAH_01859 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
APGMFHAH_01860 7.28e-101 - - - K - - - acetyltransferase
APGMFHAH_01861 1.7e-260 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
APGMFHAH_01862 6.5e-306 yhfN - - O - - - Peptidase M48
APGMFHAH_01863 2.28e-84 yhfM - - - - - - -
APGMFHAH_01864 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
APGMFHAH_01865 1.01e-141 yhfK - - GM - - - NmrA-like family
APGMFHAH_01866 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
APGMFHAH_01867 1.63e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
APGMFHAH_01868 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APGMFHAH_01869 1.79e-92 - - - S - - - ASCH
APGMFHAH_01870 1.55e-252 yhfE - - G - - - peptidase M42
APGMFHAH_01871 2.67e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
APGMFHAH_01872 8.77e-237 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APGMFHAH_01873 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
APGMFHAH_01874 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_01875 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
APGMFHAH_01876 3.99e-230 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
APGMFHAH_01877 6.13e-258 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
APGMFHAH_01878 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
APGMFHAH_01879 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
APGMFHAH_01880 1e-44 - - - C - - - Rubrerythrin
APGMFHAH_01881 1.82e-310 yhfA - - C - - - membrane
APGMFHAH_01882 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
APGMFHAH_01883 2.89e-161 ecsC - - S - - - EcsC protein family
APGMFHAH_01884 2.55e-271 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
APGMFHAH_01885 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
APGMFHAH_01886 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
APGMFHAH_01887 7.5e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APGMFHAH_01888 6.32e-104 trpP - - S - - - Tryptophan transporter TrpP
APGMFHAH_01889 1.74e-54 yhaH - - S - - - YtxH-like protein
APGMFHAH_01890 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
APGMFHAH_01891 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
APGMFHAH_01892 5.71e-116 yhaK - - S - - - Putative zincin peptidase
APGMFHAH_01893 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
APGMFHAH_01894 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
APGMFHAH_01895 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
APGMFHAH_01896 0.0 yhaN - - L - - - AAA domain
APGMFHAH_01897 4.87e-301 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
APGMFHAH_01898 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
APGMFHAH_01899 4.57e-214 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_01900 5.43e-35 - - - S - - - YhzD-like protein
APGMFHAH_01901 3.41e-169 yhaR - - I - - - enoyl-CoA hydratase
APGMFHAH_01903 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
APGMFHAH_01904 1.85e-267 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
APGMFHAH_01905 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
APGMFHAH_01906 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
APGMFHAH_01907 1.29e-261 yhaZ - - L - - - DNA alkylation repair enzyme
APGMFHAH_01908 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
APGMFHAH_01909 4.16e-259 yheB - - S - - - Belongs to the UPF0754 family
APGMFHAH_01910 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
APGMFHAH_01911 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
APGMFHAH_01912 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
APGMFHAH_01913 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
APGMFHAH_01914 1.29e-140 yheG - - GM - - - NAD(P)H-binding
APGMFHAH_01915 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
APGMFHAH_01916 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
APGMFHAH_01917 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
APGMFHAH_01918 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
APGMFHAH_01919 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
APGMFHAH_01920 9.72e-192 nodB1 - - G - - - deacetylase
APGMFHAH_01921 9.4e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
APGMFHAH_01922 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
APGMFHAH_01923 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
APGMFHAH_01924 3.68e-172 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
APGMFHAH_01925 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APGMFHAH_01926 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
APGMFHAH_01927 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
APGMFHAH_01928 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
APGMFHAH_01929 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
APGMFHAH_01930 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
APGMFHAH_01931 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
APGMFHAH_01932 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APGMFHAH_01933 2.74e-243 yhdN - - C - - - Aldo keto reductase
APGMFHAH_01934 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_01935 6.13e-258 yhdL - - S - - - Sigma factor regulator N-terminal
APGMFHAH_01936 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
APGMFHAH_01937 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APGMFHAH_01938 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APGMFHAH_01939 1.01e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
APGMFHAH_01940 8.4e-315 yhdG - - E ko:K03294 - ko00000 amino acid
APGMFHAH_01941 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_01942 8.75e-260 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
APGMFHAH_01943 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_01944 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
APGMFHAH_01945 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
APGMFHAH_01946 1.87e-140 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
APGMFHAH_01947 1.91e-44 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
APGMFHAH_01948 2.42e-140 yagB - - S ko:K06950 - ko00000 phosphohydrolase
APGMFHAH_01949 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
APGMFHAH_01950 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APGMFHAH_01951 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
APGMFHAH_01952 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
APGMFHAH_01953 1.17e-22 degR - - - - - - -
APGMFHAH_01954 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
APGMFHAH_01955 1.54e-37 ypeQ - - S - - - Zinc-finger
APGMFHAH_01956 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
APGMFHAH_01957 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APGMFHAH_01958 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
APGMFHAH_01959 5.23e-05 - - - - ko:K06429 - ko00000 -
APGMFHAH_01960 1.31e-212 ypcP - - L - - - 5'3' exonuclease
APGMFHAH_01961 7.57e-12 - - - - - - - -
APGMFHAH_01962 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
APGMFHAH_01963 0.0 ypbR - - S - - - Dynamin family
APGMFHAH_01964 1.36e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
APGMFHAH_01965 4.08e-41 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
APGMFHAH_01966 1.49e-201 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
APGMFHAH_01967 3.51e-291 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
APGMFHAH_01968 1.65e-128 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
APGMFHAH_01969 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
APGMFHAH_01970 5.8e-224 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
APGMFHAH_01971 2.84e-130 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
APGMFHAH_01972 3.17e-234 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
APGMFHAH_01973 7.8e-238 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
APGMFHAH_01974 5.11e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
APGMFHAH_01975 3.8e-175 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_01976 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
APGMFHAH_01978 2.84e-286 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
APGMFHAH_01979 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
APGMFHAH_01980 3.99e-127 ypsA - - S - - - Belongs to the UPF0398 family
APGMFHAH_01981 1.98e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
APGMFHAH_01982 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
APGMFHAH_01983 6.1e-109 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
APGMFHAH_01984 1.76e-94 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
APGMFHAH_01985 8.72e-68 yppG - - S - - - YppG-like protein
APGMFHAH_01986 9.21e-11 - - - S - - - YppF-like protein
APGMFHAH_01987 3.57e-103 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
APGMFHAH_01988 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
APGMFHAH_01989 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
APGMFHAH_01993 2.98e-53 - - - - - - - -
APGMFHAH_01994 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
APGMFHAH_01995 8.35e-171 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
APGMFHAH_01996 9.99e-59 - - - - - - - -
APGMFHAH_01997 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
APGMFHAH_01998 9.13e-135 ywqM - - K - - - Transcriptional regulator
APGMFHAH_01999 1.35e-102 - - - E - - - amino acid
APGMFHAH_02007 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
APGMFHAH_02008 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
APGMFHAH_02009 1.08e-140 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
APGMFHAH_02010 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_02011 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
APGMFHAH_02012 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
APGMFHAH_02013 1.31e-243 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
APGMFHAH_02014 2.45e-89 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
APGMFHAH_02015 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
APGMFHAH_02016 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
APGMFHAH_02017 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
APGMFHAH_02018 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
APGMFHAH_02019 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APGMFHAH_02020 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
APGMFHAH_02021 1.54e-75 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
APGMFHAH_02022 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
APGMFHAH_02023 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
APGMFHAH_02024 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
APGMFHAH_02025 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
APGMFHAH_02026 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
APGMFHAH_02027 3.58e-257 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
APGMFHAH_02028 4.19e-75 ydbP - - CO - - - Thioredoxin
APGMFHAH_02029 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APGMFHAH_02031 1.49e-26 - - - S - - - Fur-regulated basic protein B
APGMFHAH_02032 5.03e-278 ydbM - - I - - - acyl-CoA dehydrogenase
APGMFHAH_02033 9.32e-70 ydbL - - - - - - -
APGMFHAH_02034 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APGMFHAH_02035 1.24e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_02036 8.37e-258 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
APGMFHAH_02037 4.42e-130 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
APGMFHAH_02038 4.75e-307 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
APGMFHAH_02039 4.66e-257 ycbU - - E - - - Selenocysteine lyase
APGMFHAH_02040 3.43e-154 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
APGMFHAH_02041 3.09e-159 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APGMFHAH_02042 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APGMFHAH_02043 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
APGMFHAH_02044 6.36e-173 ycbR - - T - - - vWA found in TerF C terminus
APGMFHAH_02045 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
APGMFHAH_02046 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
APGMFHAH_02047 1.73e-149 - - - S - - - ABC-2 family transporter protein
APGMFHAH_02048 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_02049 4.37e-214 ycbM - - T - - - Histidine kinase
APGMFHAH_02050 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_02051 4.05e-215 eamA1 - - EG - - - spore germination
APGMFHAH_02052 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
APGMFHAH_02053 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
APGMFHAH_02054 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
APGMFHAH_02055 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
APGMFHAH_02056 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
APGMFHAH_02057 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_02058 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APGMFHAH_02059 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
APGMFHAH_02060 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
APGMFHAH_02061 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_02062 1.77e-237 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
APGMFHAH_02063 0.0 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
APGMFHAH_02064 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
APGMFHAH_02065 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
APGMFHAH_02066 1.25e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
APGMFHAH_02068 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
APGMFHAH_02069 1.01e-172 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
APGMFHAH_02070 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_02071 6.04e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APGMFHAH_02072 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
APGMFHAH_02074 9.96e-22 - - - - - - - -
APGMFHAH_02075 7.74e-301 - - - I - - - Pfam Lipase (class 3)
APGMFHAH_02076 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
APGMFHAH_02077 2.51e-19 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02079 6.79e-11 - - - S - - - Family of unknown function (DUF5316)
APGMFHAH_02081 2.23e-90 - - - S - - - Regulatory protein YrvL
APGMFHAH_02082 9.3e-126 ymcC - - S - - - Membrane
APGMFHAH_02083 1.02e-134 pksA - - K - - - Transcriptional regulator
APGMFHAH_02084 8.03e-81 ymzB - - - - - - -
APGMFHAH_02085 1.88e-207 - - - S - - - Metallo-beta-lactamase superfamily
APGMFHAH_02086 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
APGMFHAH_02088 3.96e-163 ymaC - - S - - - Replication protein
APGMFHAH_02089 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
APGMFHAH_02090 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
APGMFHAH_02091 2.45e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
APGMFHAH_02093 5.41e-76 ymaF - - S - - - YmaF family
APGMFHAH_02094 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
APGMFHAH_02095 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
APGMFHAH_02096 1.63e-31 - - - - - - - -
APGMFHAH_02097 1.2e-30 ymzA - - - - - - -
APGMFHAH_02098 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
APGMFHAH_02099 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APGMFHAH_02100 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APGMFHAH_02101 3.71e-140 - - - - - - - -
APGMFHAH_02102 2.72e-148 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
APGMFHAH_02103 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
APGMFHAH_02104 7.4e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APGMFHAH_02105 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
APGMFHAH_02106 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
APGMFHAH_02107 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
APGMFHAH_02108 3.69e-32 - - - - - - - -
APGMFHAH_02109 1.68e-53 - - - - - - - -
APGMFHAH_02110 4.6e-309 - - - M - - - nucleic acid phosphodiester bond hydrolysis
APGMFHAH_02112 1.68e-13 - - - - - - - -
APGMFHAH_02114 1.46e-105 - - - - - - - -
APGMFHAH_02115 4.13e-51 - - - - - - - -
APGMFHAH_02116 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
APGMFHAH_02117 9.3e-51 ynaC - - - - - - -
APGMFHAH_02118 3.65e-81 ynaC - - - - - - -
APGMFHAH_02119 2.63e-11 - - - - - - - -
APGMFHAH_02120 1e-89 - - - S - - - Phage terminase, small subunit
APGMFHAH_02121 1.37e-277 - - - S - - - Phage Terminase
APGMFHAH_02122 2.58e-14 - - - - - - - -
APGMFHAH_02123 4.77e-273 - - - S - - - Phage portal protein
APGMFHAH_02124 9.36e-135 - - - S - - - peptidase activity
APGMFHAH_02125 4.87e-227 - - - S - - - capsid protein
APGMFHAH_02126 7.93e-09 - - - - - - - -
APGMFHAH_02127 7.91e-39 - - - - - - - -
APGMFHAH_02128 5.25e-34 - - - S - - - Phage gp6-like head-tail connector protein
APGMFHAH_02129 4.59e-64 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
APGMFHAH_02130 1.42e-40 - - - - - - - -
APGMFHAH_02131 9.75e-79 - - - - - - - -
APGMFHAH_02132 1.58e-36 - - - - - - - -
APGMFHAH_02133 4.09e-16 - - - - - - - -
APGMFHAH_02134 0.0 - - - S - - - peptidoglycan catabolic process
APGMFHAH_02135 1.96e-141 - - - S - - - Phage tail protein
APGMFHAH_02136 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
APGMFHAH_02137 0.0 - - - - - - - -
APGMFHAH_02138 2.1e-250 - - - S - - - Domain of unknown function (DUF2479)
APGMFHAH_02141 1.79e-74 - - - S - - - Bacteriophage holin family
APGMFHAH_02142 6.14e-142 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
APGMFHAH_02145 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
APGMFHAH_02148 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_02149 9.98e-128 - - - K - - - Bacterial regulatory proteins, tetR family
APGMFHAH_02150 3.52e-71 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
APGMFHAH_02151 5.79e-97 yvaD - - S - - - Family of unknown function (DUF5360)
APGMFHAH_02152 0.0 - - - S - - - Fusaric acid resistance protein-like
APGMFHAH_02153 7.68e-25 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APGMFHAH_02154 2.92e-88 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APGMFHAH_02155 3.3e-246 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
APGMFHAH_02156 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
APGMFHAH_02157 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
APGMFHAH_02158 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
APGMFHAH_02159 2.42e-172 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
APGMFHAH_02160 3.3e-251 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
APGMFHAH_02161 3.45e-137 bdbD - - O - - - Thioredoxin
APGMFHAH_02162 1.64e-94 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
APGMFHAH_02163 4.54e-205 ytbE - - S - - - reductase
APGMFHAH_02164 5.44e-260 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
APGMFHAH_02165 9.85e-88 ytcD - - K - - - Transcriptional regulator
APGMFHAH_02166 1.22e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
APGMFHAH_02167 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
APGMFHAH_02168 3.44e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APGMFHAH_02169 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
APGMFHAH_02170 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
APGMFHAH_02171 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
APGMFHAH_02172 5.5e-202 ytxC - - S - - - YtxC-like family
APGMFHAH_02174 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
APGMFHAH_02175 1.15e-188 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
APGMFHAH_02176 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_02177 4.62e-165 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
APGMFHAH_02178 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APGMFHAH_02179 5.34e-150 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
APGMFHAH_02181 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
APGMFHAH_02182 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
APGMFHAH_02183 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
APGMFHAH_02184 1.27e-59 ysdA - - S - - - Membrane
APGMFHAH_02185 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
APGMFHAH_02186 3.57e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
APGMFHAH_02187 9.92e-242 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
APGMFHAH_02188 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
APGMFHAH_02189 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
APGMFHAH_02190 6.93e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
APGMFHAH_02191 7.07e-186 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
APGMFHAH_02192 3.72e-282 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
APGMFHAH_02193 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
APGMFHAH_02194 1.94e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
APGMFHAH_02195 2.47e-189 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
APGMFHAH_02196 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
APGMFHAH_02197 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
APGMFHAH_02199 8.17e-52 ysfE 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 lactoylglutathione lyase activity
APGMFHAH_02200 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
APGMFHAH_02201 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
APGMFHAH_02202 1.24e-260 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
APGMFHAH_02203 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
APGMFHAH_02204 7.37e-170 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APGMFHAH_02205 1.81e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
APGMFHAH_02206 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
APGMFHAH_02207 1.47e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APGMFHAH_02208 2.45e-53 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APGMFHAH_02209 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
APGMFHAH_02210 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
APGMFHAH_02211 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
APGMFHAH_02212 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
APGMFHAH_02213 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
APGMFHAH_02214 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02215 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
APGMFHAH_02216 1.74e-177 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
APGMFHAH_02217 8.29e-226 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
APGMFHAH_02219 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
APGMFHAH_02220 1.87e-68 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
APGMFHAH_02221 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
APGMFHAH_02222 4.62e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
APGMFHAH_02223 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
APGMFHAH_02224 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
APGMFHAH_02225 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
APGMFHAH_02226 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
APGMFHAH_02227 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
APGMFHAH_02228 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02229 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
APGMFHAH_02230 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
APGMFHAH_02231 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
APGMFHAH_02232 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
APGMFHAH_02233 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APGMFHAH_02234 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
APGMFHAH_02236 3.36e-181 ysnF - - S - - - protein conserved in bacteria
APGMFHAH_02237 1.38e-84 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
APGMFHAH_02239 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
APGMFHAH_02240 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
APGMFHAH_02241 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APGMFHAH_02242 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APGMFHAH_02243 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
APGMFHAH_02244 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APGMFHAH_02245 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
APGMFHAH_02246 4.53e-239 ysoA - - H - - - Tetratricopeptide repeat
APGMFHAH_02247 2.54e-286 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
APGMFHAH_02248 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
APGMFHAH_02249 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
APGMFHAH_02250 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APGMFHAH_02251 5.14e-137 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
APGMFHAH_02252 4.77e-116 ysxD - - - - - - -
APGMFHAH_02253 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
APGMFHAH_02254 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
APGMFHAH_02255 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
APGMFHAH_02256 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
APGMFHAH_02257 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
APGMFHAH_02258 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
APGMFHAH_02259 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
APGMFHAH_02260 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
APGMFHAH_02261 1.53e-35 - - - - - - - -
APGMFHAH_02262 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
APGMFHAH_02263 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
APGMFHAH_02264 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
APGMFHAH_02265 2.47e-210 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
APGMFHAH_02266 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
APGMFHAH_02267 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
APGMFHAH_02268 2.14e-234 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
APGMFHAH_02269 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
APGMFHAH_02270 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
APGMFHAH_02271 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
APGMFHAH_02272 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
APGMFHAH_02273 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
APGMFHAH_02274 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
APGMFHAH_02275 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
APGMFHAH_02276 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
APGMFHAH_02277 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
APGMFHAH_02278 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
APGMFHAH_02279 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APGMFHAH_02280 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
APGMFHAH_02281 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
APGMFHAH_02282 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
APGMFHAH_02283 7.06e-292 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
APGMFHAH_02284 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
APGMFHAH_02285 3.99e-199 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
APGMFHAH_02286 2.55e-269 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
APGMFHAH_02287 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
APGMFHAH_02288 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APGMFHAH_02289 3.51e-164 yebC - - K - - - transcriptional regulatory protein
APGMFHAH_02290 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
APGMFHAH_02291 3.62e-67 - - - S - - - Family of unknown function (DUF5412)
APGMFHAH_02293 8.28e-85 yrzF - - T - - - serine threonine protein kinase
APGMFHAH_02294 2.92e-23 yrzF - - T - - - serine threonine protein kinase
APGMFHAH_02295 1.53e-245 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
APGMFHAH_02296 3.85e-239 csbX - - EGP - - - the major facilitator superfamily
APGMFHAH_02297 7.54e-66 csbX - - EGP - - - the major facilitator superfamily
APGMFHAH_02298 1.3e-120 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
APGMFHAH_02299 1.64e-136 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
APGMFHAH_02300 3.72e-238 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
APGMFHAH_02301 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
APGMFHAH_02302 2.46e-247 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
APGMFHAH_02303 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
APGMFHAH_02304 1.24e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
APGMFHAH_02305 6.2e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
APGMFHAH_02306 8.64e-145 yrbG - - S - - - membrane
APGMFHAH_02307 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APGMFHAH_02308 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
APGMFHAH_02309 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APGMFHAH_02310 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
APGMFHAH_02311 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
APGMFHAH_02312 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
APGMFHAH_02313 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
APGMFHAH_02314 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APGMFHAH_02315 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
APGMFHAH_02316 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
APGMFHAH_02318 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
APGMFHAH_02319 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
APGMFHAH_02320 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
APGMFHAH_02321 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
APGMFHAH_02322 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02323 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
APGMFHAH_02324 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
APGMFHAH_02325 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
APGMFHAH_02326 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
APGMFHAH_02327 9.73e-106 yrrD - - S - - - protein conserved in bacteria
APGMFHAH_02328 4.87e-41 yrzR - - - - - - -
APGMFHAH_02329 8.96e-11 - - - S - - - Protein of unknown function (DUF3918)
APGMFHAH_02330 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
APGMFHAH_02331 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
APGMFHAH_02332 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
APGMFHAH_02333 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
APGMFHAH_02334 1.25e-241 yrrI - - S - - - AI-2E family transporter
APGMFHAH_02335 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APGMFHAH_02336 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
APGMFHAH_02337 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APGMFHAH_02338 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
APGMFHAH_02339 6.17e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APGMFHAH_02340 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
APGMFHAH_02341 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
APGMFHAH_02342 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
APGMFHAH_02343 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
APGMFHAH_02344 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
APGMFHAH_02345 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
APGMFHAH_02346 2.02e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
APGMFHAH_02347 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
APGMFHAH_02348 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
APGMFHAH_02349 1.14e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APGMFHAH_02350 9.59e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
APGMFHAH_02351 2.45e-268 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
APGMFHAH_02352 6.93e-49 yrhC - - S - - - YrhC-like protein
APGMFHAH_02353 6.05e-103 yrhD - - S - - - Protein of unknown function (DUF1641)
APGMFHAH_02354 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
APGMFHAH_02355 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
APGMFHAH_02357 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
APGMFHAH_02359 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
APGMFHAH_02360 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
APGMFHAH_02361 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APGMFHAH_02362 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
APGMFHAH_02363 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APGMFHAH_02364 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
APGMFHAH_02365 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_02366 1.22e-81 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_02367 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
APGMFHAH_02368 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APGMFHAH_02369 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_02370 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APGMFHAH_02371 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
APGMFHAH_02372 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
APGMFHAH_02373 1.05e-26 yxzF - - - - - - -
APGMFHAH_02374 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
APGMFHAH_02375 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
APGMFHAH_02376 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
APGMFHAH_02377 1.55e-176 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APGMFHAH_02378 2.01e-211 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_02379 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
APGMFHAH_02380 1.63e-39 - - - - - - - -
APGMFHAH_02381 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
APGMFHAH_02382 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_02383 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
APGMFHAH_02384 6.19e-201 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APGMFHAH_02385 3.65e-188 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
APGMFHAH_02386 4.68e-129 ydhK - - M - - - Protein of unknown function (DUF1541)
APGMFHAH_02387 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
APGMFHAH_02388 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
APGMFHAH_02390 5.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
APGMFHAH_02391 1.67e-224 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
APGMFHAH_02392 1.46e-81 - - - - - - - -
APGMFHAH_02393 1.04e-50 - - - - - - - -
APGMFHAH_02394 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APGMFHAH_02395 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
APGMFHAH_02396 0.0 ycxD - - K - - - GntR family transcriptional regulator
APGMFHAH_02397 1.17e-198 ycxC - - EG - - - EamA-like transporter family
APGMFHAH_02398 1.48e-122 - - - S - - - YcxB-like protein
APGMFHAH_02399 1.41e-284 - - - EGP - - - Major Facilitator Superfamily
APGMFHAH_02400 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
APGMFHAH_02401 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
APGMFHAH_02402 0.0 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APGMFHAH_02403 0.0 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APGMFHAH_02404 5.93e-85 hxlR - - K - - - transcriptional
APGMFHAH_02405 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
APGMFHAH_02406 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
APGMFHAH_02407 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_02408 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_02409 6.53e-99 nucA - - M - - - Deoxyribonuclease NucA/NucB
APGMFHAH_02410 3.36e-91 nin - - S - - - Competence protein J (ComJ)
APGMFHAH_02411 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
APGMFHAH_02412 2.42e-27 - - - S - - - AAA domain
APGMFHAH_02413 2.13e-113 - - - S - - - AAA domain
APGMFHAH_02414 2.49e-27 - - - - - - - -
APGMFHAH_02415 1.06e-57 - - - K - - - MarR family
APGMFHAH_02416 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
APGMFHAH_02417 1.11e-96 yckC - - S - - - membrane
APGMFHAH_02420 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
APGMFHAH_02421 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
APGMFHAH_02422 2.26e-123 yciC - - S - - - GTPases (G3E family)
APGMFHAH_02423 2.72e-141 yciC - - S - - - GTPases (G3E family)
APGMFHAH_02424 1.79e-85 - - - M - - - ErfK YbiS YcfS YnhG
APGMFHAH_02425 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
APGMFHAH_02426 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
APGMFHAH_02427 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
APGMFHAH_02428 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
APGMFHAH_02429 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APGMFHAH_02430 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
APGMFHAH_02431 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
APGMFHAH_02432 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
APGMFHAH_02433 7.22e-191 ycgS - - I - - - alpha/beta hydrolase fold
APGMFHAH_02434 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
APGMFHAH_02435 7.72e-195 ycgQ - - S ko:K08986 - ko00000 membrane
APGMFHAH_02436 6.5e-287 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
APGMFHAH_02437 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APGMFHAH_02438 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
APGMFHAH_02439 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
APGMFHAH_02440 1.29e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
APGMFHAH_02441 7.75e-232 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
APGMFHAH_02442 8.95e-225 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
APGMFHAH_02443 4.85e-182 - - - Q - - - ubiE/COQ5 methyltransferase family
APGMFHAH_02444 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
APGMFHAH_02445 1.08e-139 tmrB - - S - - - AAA domain
APGMFHAH_02446 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
APGMFHAH_02447 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
APGMFHAH_02448 8.63e-97 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_02449 2.07e-192 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
APGMFHAH_02450 1.33e-268 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
APGMFHAH_02451 2.38e-82 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
APGMFHAH_02452 1.63e-232 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
APGMFHAH_02453 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
APGMFHAH_02454 2.45e-23 - - - S - - - YrzO-like protein
APGMFHAH_02455 7.28e-218 yrdR - - EG - - - EamA-like transporter family
APGMFHAH_02456 1.4e-203 - - - K - - - Transcriptional regulator
APGMFHAH_02457 3.02e-254 trkA - - P ko:K07222 - ko00000 Oxidoreductase
APGMFHAH_02458 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
APGMFHAH_02460 3.92e-289 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
APGMFHAH_02461 2.12e-65 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
APGMFHAH_02462 1.88e-175 azlC - - E - - - AzlC protein
APGMFHAH_02463 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
APGMFHAH_02464 7.91e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
APGMFHAH_02465 3.11e-289 cypA 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
APGMFHAH_02467 7.38e-131 yrdC - - Q - - - Isochorismatase family
APGMFHAH_02468 1.09e-73 - - - S - - - Protein of unknown function (DUF2568)
APGMFHAH_02470 2.01e-118 yrdA - - S - - - DinB family
APGMFHAH_02471 1.48e-212 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
APGMFHAH_02472 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
APGMFHAH_02473 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
APGMFHAH_02474 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
APGMFHAH_02476 4.22e-164 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
APGMFHAH_02477 2.5e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_02478 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
APGMFHAH_02479 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
APGMFHAH_02480 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_02481 1.19e-191 - - - S - - - Alpha beta hydrolase
APGMFHAH_02482 6.61e-80 - - - T - - - sh3 domain protein
APGMFHAH_02483 1.05e-81 - - - T - - - sh3 domain protein
APGMFHAH_02484 1.1e-85 - - - E - - - Glyoxalase-like domain
APGMFHAH_02485 4.04e-48 yraG - - - ko:K06440 - ko00000 -
APGMFHAH_02486 9.61e-84 yraF - - M - - - Spore coat protein
APGMFHAH_02487 3.71e-283 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
APGMFHAH_02488 6.11e-36 yraE - - - ko:K06440 - ko00000 -
APGMFHAH_02489 4.9e-64 yraD - - M ko:K06439 - ko00000 Spore coat protein
APGMFHAH_02490 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
APGMFHAH_02491 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
APGMFHAH_02492 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
APGMFHAH_02493 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
APGMFHAH_02494 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
APGMFHAH_02495 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
APGMFHAH_02496 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
APGMFHAH_02497 7.63e-107 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
APGMFHAH_02498 2.66e-97 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
APGMFHAH_02499 0.0 levR - - K - - - PTS system fructose IIA component
APGMFHAH_02500 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_02501 5.63e-137 yrhP - - E - - - LysE type translocator
APGMFHAH_02502 1.98e-192 yrhO - - K - - - Archaeal transcriptional regulator TrmB
APGMFHAH_02503 8.25e-49 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_02504 3.16e-51 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_02505 7.4e-193 rsiV - - S - - - Protein of unknown function (DUF3298)
APGMFHAH_02506 0.0 oatA - - I - - - Acyltransferase family
APGMFHAH_02507 6.32e-59 yrhK - - S - - - YrhK-like protein
APGMFHAH_02508 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
APGMFHAH_02509 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
APGMFHAH_02510 1.88e-118 yrhH - - Q - - - methyltransferase
APGMFHAH_02511 1.01e-25 - - - S - - - Protein of unknown function (DUF3813)
APGMFHAH_02512 5.29e-199 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
APGMFHAH_02513 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
APGMFHAH_02514 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
APGMFHAH_02515 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
APGMFHAH_02516 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
APGMFHAH_02517 3.24e-114 yitZ - - G - - - Major Facilitator Superfamily
APGMFHAH_02518 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APGMFHAH_02519 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
APGMFHAH_02520 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
APGMFHAH_02521 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
APGMFHAH_02522 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
APGMFHAH_02523 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
APGMFHAH_02524 4.27e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
APGMFHAH_02525 1.52e-81 ylyA - - T - - - COG1734 DnaK suppressor protein
APGMFHAH_02526 2.71e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
APGMFHAH_02527 5.85e-224 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
APGMFHAH_02528 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
APGMFHAH_02529 2.61e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
APGMFHAH_02530 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
APGMFHAH_02531 4.86e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
APGMFHAH_02532 1.31e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
APGMFHAH_02533 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
APGMFHAH_02534 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
APGMFHAH_02535 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
APGMFHAH_02536 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
APGMFHAH_02537 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
APGMFHAH_02538 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
APGMFHAH_02539 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
APGMFHAH_02540 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
APGMFHAH_02541 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
APGMFHAH_02542 6.89e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
APGMFHAH_02543 2.06e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
APGMFHAH_02544 9.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
APGMFHAH_02545 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
APGMFHAH_02546 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
APGMFHAH_02547 8.41e-202 yloC - - S - - - stress-induced protein
APGMFHAH_02548 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
APGMFHAH_02549 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
APGMFHAH_02550 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
APGMFHAH_02551 4.21e-285 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APGMFHAH_02552 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APGMFHAH_02553 8.3e-110 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APGMFHAH_02554 2.03e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
APGMFHAH_02555 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APGMFHAH_02556 2.16e-263 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APGMFHAH_02557 8.34e-179 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
APGMFHAH_02558 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
APGMFHAH_02559 7.9e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
APGMFHAH_02560 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
APGMFHAH_02561 1.35e-155 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
APGMFHAH_02562 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
APGMFHAH_02563 3.01e-77 yloU - - S - - - protein conserved in bacteria
APGMFHAH_02564 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
APGMFHAH_02565 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
APGMFHAH_02566 2.4e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
APGMFHAH_02567 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APGMFHAH_02568 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
APGMFHAH_02569 8.33e-230 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
APGMFHAH_02570 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
APGMFHAH_02571 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
APGMFHAH_02572 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
APGMFHAH_02573 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
APGMFHAH_02574 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
APGMFHAH_02575 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APGMFHAH_02576 1.67e-114 - - - - - - - -
APGMFHAH_02577 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
APGMFHAH_02578 1.13e-307 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APGMFHAH_02579 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
APGMFHAH_02580 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
APGMFHAH_02581 3.41e-80 ylqD - - S - - - YlqD protein
APGMFHAH_02582 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
APGMFHAH_02583 1.98e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
APGMFHAH_02584 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
APGMFHAH_02585 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APGMFHAH_02586 1.18e-174 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
APGMFHAH_02587 0.0 ylqG - - - - - - -
APGMFHAH_02588 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
APGMFHAH_02589 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
APGMFHAH_02590 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
APGMFHAH_02591 3.48e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
APGMFHAH_02592 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APGMFHAH_02593 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
APGMFHAH_02594 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
APGMFHAH_02595 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
APGMFHAH_02596 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
APGMFHAH_02597 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
APGMFHAH_02598 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
APGMFHAH_02599 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
APGMFHAH_02600 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
APGMFHAH_02601 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
APGMFHAH_02602 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APGMFHAH_02603 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
APGMFHAH_02604 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
APGMFHAH_02605 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
APGMFHAH_02606 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
APGMFHAH_02607 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
APGMFHAH_02608 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
APGMFHAH_02609 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
APGMFHAH_02610 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
APGMFHAH_02611 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
APGMFHAH_02612 1.6e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APGMFHAH_02613 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
APGMFHAH_02614 3.99e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
APGMFHAH_02615 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
APGMFHAH_02616 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
APGMFHAH_02617 1.53e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
APGMFHAH_02618 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APGMFHAH_02619 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APGMFHAH_02620 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
APGMFHAH_02621 3.14e-200 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
APGMFHAH_02622 1.81e-252 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
APGMFHAH_02623 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
APGMFHAH_02624 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
APGMFHAH_02625 1.45e-143 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
APGMFHAH_02626 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
APGMFHAH_02627 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_02628 6.91e-101 ylxL - - - - - - -
APGMFHAH_02629 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
APGMFHAH_02630 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
APGMFHAH_02631 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
APGMFHAH_02632 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
APGMFHAH_02633 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APGMFHAH_02634 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
APGMFHAH_02635 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
APGMFHAH_02636 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
APGMFHAH_02637 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
APGMFHAH_02638 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APGMFHAH_02639 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
APGMFHAH_02640 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
APGMFHAH_02641 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
APGMFHAH_02642 6.16e-63 ylxQ - - J - - - ribosomal protein
APGMFHAH_02643 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
APGMFHAH_02644 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
APGMFHAH_02645 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
APGMFHAH_02646 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
APGMFHAH_02647 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
APGMFHAH_02648 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APGMFHAH_02649 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
APGMFHAH_02650 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
APGMFHAH_02651 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
APGMFHAH_02652 1.53e-56 ymxH - - S - - - YlmC YmxH family
APGMFHAH_02653 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
APGMFHAH_02654 1.36e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
APGMFHAH_02655 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APGMFHAH_02656 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
APGMFHAH_02657 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APGMFHAH_02658 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APGMFHAH_02659 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
APGMFHAH_02660 4.94e-44 - - - S - - - YlzJ-like protein
APGMFHAH_02661 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
APGMFHAH_02662 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02663 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_02664 9.47e-299 albE - - S - - - Peptidase M16
APGMFHAH_02665 2.37e-309 ymfH - - S - - - zinc protease
APGMFHAH_02666 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
APGMFHAH_02667 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
APGMFHAH_02668 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
APGMFHAH_02669 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
APGMFHAH_02670 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APGMFHAH_02671 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
APGMFHAH_02672 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APGMFHAH_02673 1.82e-276 pbpX - - V - - - Beta-lactamase
APGMFHAH_02674 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
APGMFHAH_02675 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
APGMFHAH_02676 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
APGMFHAH_02677 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
APGMFHAH_02678 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APGMFHAH_02679 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
APGMFHAH_02680 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
APGMFHAH_02681 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
APGMFHAH_02682 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
APGMFHAH_02683 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APGMFHAH_02688 5.52e-31 - - - M - - - ArpU family transcriptional regulator
APGMFHAH_02689 4.71e-122 rok - - K - - - Repressor of ComK
APGMFHAH_02690 4.23e-104 ykuV - - CO - - - thiol-disulfide
APGMFHAH_02691 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
APGMFHAH_02692 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
APGMFHAH_02693 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
APGMFHAH_02694 2.67e-274 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
APGMFHAH_02695 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
APGMFHAH_02696 1.3e-104 fld - - C ko:K03839 - ko00000 Flavodoxin
APGMFHAH_02697 1.74e-222 ykuO - - - - - - -
APGMFHAH_02698 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
APGMFHAH_02699 7.61e-215 ccpC - - K - - - Transcriptional regulator
APGMFHAH_02700 6.01e-99 ykuL - - S - - - CBS domain
APGMFHAH_02701 7.83e-38 ykzF - - S - - - Antirepressor AbbA
APGMFHAH_02702 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
APGMFHAH_02703 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
APGMFHAH_02704 2.37e-293 ykuI - - T - - - Diguanylate phosphodiesterase
APGMFHAH_02705 1.83e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_02706 3.48e-212 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
APGMFHAH_02707 5.84e-115 ykuD - - S - - - protein conserved in bacteria
APGMFHAH_02708 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_02709 3.71e-110 ykyB - - S - - - YkyB-like protein
APGMFHAH_02710 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
APGMFHAH_02711 1.05e-22 - - - - - - - -
APGMFHAH_02712 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
APGMFHAH_02713 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_02714 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
APGMFHAH_02715 8.32e-151 ykwD - - J - - - protein with SCP PR1 domains
APGMFHAH_02716 2.96e-245 yceH - - P - - - Belongs to the TelA family
APGMFHAH_02717 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
APGMFHAH_02718 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
APGMFHAH_02719 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
APGMFHAH_02720 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
APGMFHAH_02721 3.75e-141 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
APGMFHAH_02722 1.2e-237 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APGMFHAH_02723 4.63e-173 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APGMFHAH_02724 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APGMFHAH_02725 7.92e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
APGMFHAH_02726 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
APGMFHAH_02727 6.85e-180 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
APGMFHAH_02728 2.93e-45 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
APGMFHAH_02729 5.15e-161 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
APGMFHAH_02730 1.53e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
APGMFHAH_02731 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_02732 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_02733 1.5e-227 ycdA - - S - - - Domain of unknown function (DUF5105)
APGMFHAH_02734 1.29e-182 yccK - - C - - - Aldo keto reductase
APGMFHAH_02735 2.9e-28 yccK - - C - - - Aldo keto reductase
APGMFHAH_02736 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
APGMFHAH_02737 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
APGMFHAH_02738 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
APGMFHAH_02739 6.18e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
APGMFHAH_02740 2.49e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
APGMFHAH_02741 4.32e-78 - - - S - - - RDD family
APGMFHAH_02742 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
APGMFHAH_02743 3.49e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
APGMFHAH_02744 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
APGMFHAH_02745 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APGMFHAH_02746 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APGMFHAH_02747 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
APGMFHAH_02748 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
APGMFHAH_02749 6.97e-189 yerO - - K - - - Transcriptional regulator
APGMFHAH_02750 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APGMFHAH_02751 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
APGMFHAH_02752 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APGMFHAH_02753 1.14e-27 - - - - - - - -
APGMFHAH_02754 0.0 - - - K - - - SIR2-like domain
APGMFHAH_02756 2.84e-72 - - - S - - - Protein of unknown function, DUF600
APGMFHAH_02757 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
APGMFHAH_02759 5.68e-126 - - - L - - - endonuclease activity
APGMFHAH_02760 1.23e-14 - - - S - - - Pfam:DUF1311
APGMFHAH_02761 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
APGMFHAH_02763 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
APGMFHAH_02765 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02766 4.95e-107 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
APGMFHAH_02767 1.23e-195 yesF - - GM - - - NAD(P)H-binding
APGMFHAH_02768 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
APGMFHAH_02769 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
APGMFHAH_02770 1.04e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
APGMFHAH_02771 4.15e-131 yesJ - - K - - - Acetyltransferase (GNAT) family
APGMFHAH_02773 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
APGMFHAH_02774 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_02775 2.41e-199 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
APGMFHAH_02776 7.99e-312 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
APGMFHAH_02777 1.17e-217 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
APGMFHAH_02778 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
APGMFHAH_02779 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
APGMFHAH_02780 0.0 yesS - - K - - - Transcriptional regulator
APGMFHAH_02781 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
APGMFHAH_02782 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
APGMFHAH_02783 2.32e-144 - - - S - - - Protein of unknown function, DUF624
APGMFHAH_02784 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
APGMFHAH_02785 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
APGMFHAH_02786 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
APGMFHAH_02787 2.73e-80 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
APGMFHAH_02788 8.37e-153 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
APGMFHAH_02789 2.97e-193 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
APGMFHAH_02790 2.25e-127 yetA - - - - - - -
APGMFHAH_02791 5.02e-234 yetA - - - - - - -
APGMFHAH_02792 1.71e-209 yetA - - - - - - -
APGMFHAH_02793 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
APGMFHAH_02794 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
APGMFHAH_02795 1.3e-207 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
APGMFHAH_02796 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
APGMFHAH_02797 3.66e-157 yetF - - S - - - membrane
APGMFHAH_02798 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
APGMFHAH_02799 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APGMFHAH_02800 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
APGMFHAH_02801 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
APGMFHAH_02802 1.14e-130 yoaB - - EGP - - - the major facilitator superfamily
APGMFHAH_02803 6.17e-146 yoaB - - EGP - - - the major facilitator superfamily
APGMFHAH_02804 2.23e-112 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
APGMFHAH_02805 7.71e-128 - - - S - - - Protein of unknown function (DUF421)
APGMFHAH_02806 0.0 - - - I - - - PLD-like domain
APGMFHAH_02807 4.61e-63 - - - S - - - Protein of unknown function (DUF421)
APGMFHAH_02808 9.73e-194 - - - S - - - membrane
APGMFHAH_02809 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
APGMFHAH_02810 4.34e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
APGMFHAH_02811 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
APGMFHAH_02812 5.84e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
APGMFHAH_02813 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
APGMFHAH_02815 9.14e-206 - - - P - - - Catalase
APGMFHAH_02816 4.26e-33 - - - S - - - Protein of unknown function (DUF2642)
APGMFHAH_02817 2.28e-13 - - - S - - - TIGRFAM germination protein, Ger(x)C family
APGMFHAH_02818 3.4e-193 - - - EG - - - Spore germination protein
APGMFHAH_02819 5.09e-42 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
APGMFHAH_02820 2.2e-100 - - - - - - - -
APGMFHAH_02821 2.72e-59 - - - L - - - Transposase and inactivated derivatives, TnpA family
APGMFHAH_02822 1.88e-19 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
APGMFHAH_02823 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
APGMFHAH_02824 3.56e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
APGMFHAH_02825 1.79e-145 yoaK - - S - - - Membrane
APGMFHAH_02826 2.19e-247 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
APGMFHAH_02827 1.27e-105 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
APGMFHAH_02830 1.45e-207 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
APGMFHAH_02831 2.59e-64 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
APGMFHAH_02834 8.19e-108 - - - - - - - -
APGMFHAH_02835 1.42e-215 yoaR - - V - - - vancomycin resistance protein
APGMFHAH_02836 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
APGMFHAH_02837 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02838 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
APGMFHAH_02839 1.35e-202 yoaU - - K - - - LysR substrate binding domain
APGMFHAH_02840 3.7e-201 yoaV - - EG - - - EamA-like transporter family
APGMFHAH_02841 1.89e-100 yoaW - - - - - - -
APGMFHAH_02842 4.88e-147 lin0465 - - S - - - DJ-1/PfpI family
APGMFHAH_02843 8.51e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
APGMFHAH_02846 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
APGMFHAH_02847 2.16e-156 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
APGMFHAH_02848 2.11e-49 - - - S - - - TM2 domain
APGMFHAH_02849 1.73e-70 - - - K - - - Helix-turn-helix
APGMFHAH_02852 1.45e-38 - - - - - - - -
APGMFHAH_02854 7.95e-220 - - - S - - - Acetyl xylan esterase (AXE1)
APGMFHAH_02855 2.53e-241 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_02856 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
APGMFHAH_02857 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
APGMFHAH_02858 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
APGMFHAH_02859 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
APGMFHAH_02860 1.22e-68 ytwF - - P - - - Sulfurtransferase
APGMFHAH_02861 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
APGMFHAH_02862 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
APGMFHAH_02863 1.49e-180 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
APGMFHAH_02864 4.05e-267 yttB - - EGP - - - Major facilitator superfamily
APGMFHAH_02865 5.75e-78 yttA - - S - - - Pfam Transposase IS66
APGMFHAH_02866 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
APGMFHAH_02867 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_02868 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
APGMFHAH_02869 2.14e-165 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_02870 9.81e-297 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
APGMFHAH_02871 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_02872 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
APGMFHAH_02873 4.87e-215 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
APGMFHAH_02874 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_02875 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
APGMFHAH_02877 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
APGMFHAH_02878 2.35e-244 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
APGMFHAH_02879 2.75e-136 ytqB - - J - - - Putative rRNA methylase
APGMFHAH_02880 4.81e-276 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
APGMFHAH_02881 6.67e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
APGMFHAH_02882 6.85e-87 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APGMFHAH_02883 1.71e-135 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_02884 2.12e-64 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_02885 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
APGMFHAH_02886 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APGMFHAH_02887 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
APGMFHAH_02888 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
APGMFHAH_02889 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
APGMFHAH_02890 2.77e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
APGMFHAH_02891 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
APGMFHAH_02892 1.32e-183 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APGMFHAH_02893 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
APGMFHAH_02894 7.55e-80 ytkC - - S - - - Bacteriophage holin family
APGMFHAH_02895 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
APGMFHAH_02897 4.78e-95 ytkA - - S - - - YtkA-like
APGMFHAH_02898 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
APGMFHAH_02899 1.27e-133 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
APGMFHAH_02900 1.44e-55 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
APGMFHAH_02901 3e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
APGMFHAH_02902 4.02e-239 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
APGMFHAH_02903 9.9e-34 - - - S - - - Domain of Unknown Function (DUF1540)
APGMFHAH_02904 7.59e-191 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
APGMFHAH_02905 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
APGMFHAH_02906 9.74e-176 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
APGMFHAH_02907 3.77e-217 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
APGMFHAH_02908 1.94e-270 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
APGMFHAH_02909 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
APGMFHAH_02910 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APGMFHAH_02911 4.49e-193 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
APGMFHAH_02912 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
APGMFHAH_02913 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
APGMFHAH_02914 2.49e-168 yteA - - T - - - COG1734 DnaK suppressor protein
APGMFHAH_02915 6.65e-194 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
APGMFHAH_02916 6.8e-309 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
APGMFHAH_02917 2.78e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
APGMFHAH_02918 9.54e-288 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
APGMFHAH_02920 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
APGMFHAH_02921 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
APGMFHAH_02922 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
APGMFHAH_02923 6.09e-96 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
APGMFHAH_02924 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
APGMFHAH_02925 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
APGMFHAH_02926 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
APGMFHAH_02927 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APGMFHAH_02928 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APGMFHAH_02950 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
APGMFHAH_02951 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
APGMFHAH_02952 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
APGMFHAH_02953 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
APGMFHAH_02954 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
APGMFHAH_02956 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
APGMFHAH_02957 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APGMFHAH_02958 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
APGMFHAH_02959 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
APGMFHAH_02960 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
APGMFHAH_02961 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
APGMFHAH_02962 3.57e-236 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
APGMFHAH_02963 1e-101 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
APGMFHAH_02964 1.33e-181 gerBA - - EG ko:K06291,ko:K06310 - ko00000 Spore germination protein
APGMFHAH_02965 2.06e-239 gerBB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
APGMFHAH_02966 3.68e-256 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
APGMFHAH_02967 2.61e-314 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APGMFHAH_02968 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
APGMFHAH_02969 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
APGMFHAH_02970 9.23e-303 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
APGMFHAH_02971 2.29e-29 ywtC - - - - - - -
APGMFHAH_02972 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
APGMFHAH_02973 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
APGMFHAH_02974 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
APGMFHAH_02975 1.68e-224 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
APGMFHAH_02976 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APGMFHAH_02977 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
APGMFHAH_02978 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
APGMFHAH_02979 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
APGMFHAH_02980 1.22e-172 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
APGMFHAH_02981 3.97e-119 batE - - T - - - Sh3 type 3 domain protein
APGMFHAH_02982 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
APGMFHAH_02983 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
APGMFHAH_02984 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
APGMFHAH_02985 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
APGMFHAH_02986 1.37e-217 alsR - - K - - - LysR substrate binding domain
APGMFHAH_02987 9.31e-279 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
APGMFHAH_02988 4.33e-162 ywrJ - - - - - - -
APGMFHAH_02989 7.86e-162 cotB - - - ko:K06325 - ko00000 -
APGMFHAH_02990 2.08e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
APGMFHAH_02991 1e-17 - - - - - - - -
APGMFHAH_02992 1.03e-141 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APGMFHAH_02993 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
APGMFHAH_02994 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
APGMFHAH_02995 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
APGMFHAH_02996 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
APGMFHAH_02997 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
APGMFHAH_02998 1.04e-268 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APGMFHAH_02999 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
APGMFHAH_03000 2.78e-82 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
APGMFHAH_03001 3.74e-122 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
APGMFHAH_03002 6.4e-235 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
APGMFHAH_03004 6.7e-240 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
APGMFHAH_03005 4.16e-301 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
APGMFHAH_03006 1.97e-46 yuiB - - S - - - Putative membrane protein
APGMFHAH_03007 2.69e-150 yuiC - - S - - - protein conserved in bacteria
APGMFHAH_03008 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
APGMFHAH_03009 4.43e-307 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_03010 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
APGMFHAH_03011 1.81e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APGMFHAH_03012 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
APGMFHAH_03013 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
APGMFHAH_03014 1.28e-276 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
APGMFHAH_03015 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
APGMFHAH_03016 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
APGMFHAH_03017 1.21e-143 ywbG - - M - - - effector of murein hydrolase
APGMFHAH_03018 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
APGMFHAH_03019 1.28e-201 ywbI - - K - - - Transcriptional regulator
APGMFHAH_03020 5.39e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
APGMFHAH_03021 1e-145 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
APGMFHAH_03022 0.0 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
APGMFHAH_03023 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
APGMFHAH_03024 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
APGMFHAH_03025 1.26e-144 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
APGMFHAH_03026 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APGMFHAH_03027 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
APGMFHAH_03029 1.98e-157 ywcC - - K - - - transcriptional regulator
APGMFHAH_03030 3.33e-77 gtcA - - S - - - GtrA-like protein
APGMFHAH_03031 6.49e-290 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
APGMFHAH_03032 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
APGMFHAH_03033 5.11e-49 ydaS - - S - - - membrane
APGMFHAH_03034 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
APGMFHAH_03035 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APGMFHAH_03036 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
APGMFHAH_03037 1.12e-83 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
APGMFHAH_03038 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
APGMFHAH_03039 3.69e-260 - - - S - - - Acetyltransferase
APGMFHAH_03040 1.26e-268 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
APGMFHAH_03041 2.31e-178 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
APGMFHAH_03042 2.83e-237 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
APGMFHAH_03043 2.13e-169 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
APGMFHAH_03044 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APGMFHAH_03045 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
APGMFHAH_03046 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
APGMFHAH_03047 2.14e-36 yteV - - S - - - Sporulation protein Cse60
APGMFHAH_03048 2.57e-148 yteU - - S - - - Integral membrane protein
APGMFHAH_03049 5.75e-60 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
APGMFHAH_03050 1.83e-251 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
APGMFHAH_03051 2.27e-92 yteS - - G - - - transport
APGMFHAH_03052 5.61e-277 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
APGMFHAH_03053 1.31e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
APGMFHAH_03054 1.36e-202 ytdP - - K - - - Transcriptional regulator
APGMFHAH_03055 5.52e-276 ytdP - - K - - - Transcriptional regulator
APGMFHAH_03056 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
APGMFHAH_03057 1.02e-191 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
APGMFHAH_03058 1.05e-176 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
APGMFHAH_03059 6.39e-279 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
APGMFHAH_03060 1.08e-242 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
APGMFHAH_03061 6.59e-160 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
APGMFHAH_03062 5.82e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APGMFHAH_03063 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
APGMFHAH_03064 1.11e-179 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
APGMFHAH_03065 7.37e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
APGMFHAH_03066 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
APGMFHAH_03067 7.79e-105 ycgB - - - - - - -
APGMFHAH_03068 0.0 ycgA - - S - - - Membrane
APGMFHAH_03069 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
APGMFHAH_03070 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
APGMFHAH_03071 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
APGMFHAH_03072 5.2e-292 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
APGMFHAH_03073 1.38e-60 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
APGMFHAH_03074 1.19e-260 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
APGMFHAH_03075 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
APGMFHAH_03076 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
APGMFHAH_03077 2.22e-73 yuzD - - S - - - protein conserved in bacteria
APGMFHAH_03078 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
APGMFHAH_03079 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
APGMFHAH_03080 2.57e-221 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
APGMFHAH_03081 3.97e-252 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APGMFHAH_03082 1.67e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
APGMFHAH_03083 1.55e-253 yutH - - S - - - Spore coat protein
APGMFHAH_03084 2.26e-101 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
APGMFHAH_03085 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
APGMFHAH_03086 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
APGMFHAH_03087 3.2e-63 yutD - - S - - - protein conserved in bacteria
APGMFHAH_03088 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APGMFHAH_03089 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
APGMFHAH_03090 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
APGMFHAH_03091 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
APGMFHAH_03092 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
APGMFHAH_03093 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
APGMFHAH_03094 6.51e-181 yunE - - S ko:K07090 - ko00000 membrane transporter protein
APGMFHAH_03095 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
APGMFHAH_03096 2.72e-82 yunG - - - - - - -
APGMFHAH_03097 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
APGMFHAH_03098 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
APGMFHAH_03099 1.56e-295 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
APGMFHAH_03100 1.07e-273 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
APGMFHAH_03101 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
APGMFHAH_03102 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
APGMFHAH_03103 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
APGMFHAH_03104 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
APGMFHAH_03105 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
APGMFHAH_03106 2.47e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
APGMFHAH_03107 8.43e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
APGMFHAH_03108 7.18e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
APGMFHAH_03109 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
APGMFHAH_03110 4.82e-294 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
APGMFHAH_03111 4.42e-216 bsn - - L - - - Ribonuclease
APGMFHAH_03112 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
APGMFHAH_03114 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APGMFHAH_03115 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
APGMFHAH_03116 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
APGMFHAH_03117 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APGMFHAH_03119 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
APGMFHAH_03120 6.11e-106 - - - S - - - Protein of unknown function (DUF2690)
APGMFHAH_03121 2.68e-28 yjfB - - S - - - Putative motility protein
APGMFHAH_03122 2.45e-214 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
APGMFHAH_03123 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
APGMFHAH_03124 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
APGMFHAH_03125 5.56e-290 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
APGMFHAH_03126 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
APGMFHAH_03127 5.25e-113 yjgD - - S - - - Protein of unknown function (DUF1641)
APGMFHAH_03130 4.85e-143 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
APGMFHAH_03132 3.6e-63 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
APGMFHAH_03133 7.79e-205 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
APGMFHAH_03134 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
APGMFHAH_03135 1.11e-41 - - - - - - - -
APGMFHAH_03136 3.54e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
APGMFHAH_03137 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
APGMFHAH_03138 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
APGMFHAH_03139 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
APGMFHAH_03140 1.26e-20 yjlB - - S - - - Cupin domain
APGMFHAH_03141 4.85e-54 yjlB - - S - - - Cupin domain
APGMFHAH_03142 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
APGMFHAH_03143 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
APGMFHAH_03144 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
APGMFHAH_03145 1.81e-315 - - - G ko:K03292 - ko00000 symporter YjmB
APGMFHAH_03146 8.48e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
APGMFHAH_03147 2.09e-242 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
APGMFHAH_03148 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
APGMFHAH_03149 1.83e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_03150 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
APGMFHAH_03151 3.3e-236 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
APGMFHAH_03152 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
APGMFHAH_03153 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
APGMFHAH_03154 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
APGMFHAH_03155 9.46e-198 yknT - - - ko:K06437 - ko00000 -
APGMFHAH_03156 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
APGMFHAH_03157 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APGMFHAH_03158 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
APGMFHAH_03159 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
APGMFHAH_03160 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
APGMFHAH_03161 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APGMFHAH_03162 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
APGMFHAH_03163 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
APGMFHAH_03164 1.31e-150 yknW - - S - - - Yip1 domain
APGMFHAH_03165 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APGMFHAH_03166 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_03167 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
APGMFHAH_03168 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_03169 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
APGMFHAH_03170 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
APGMFHAH_03171 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
APGMFHAH_03172 5.43e-52 ykoA - - - - - - -
APGMFHAH_03173 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APGMFHAH_03174 3.74e-211 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APGMFHAH_03175 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
APGMFHAH_03176 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
APGMFHAH_03177 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
APGMFHAH_03178 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APGMFHAH_03179 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
APGMFHAH_03180 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_03181 4.23e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
APGMFHAH_03182 9.27e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
APGMFHAH_03183 3.34e-267 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
APGMFHAH_03184 9.38e-95 ytwI - - S - - - membrane
APGMFHAH_03185 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
APGMFHAH_03186 3.16e-80 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
APGMFHAH_03187 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
APGMFHAH_03188 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
APGMFHAH_03189 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
APGMFHAH_03190 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APGMFHAH_03191 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
APGMFHAH_03192 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
APGMFHAH_03193 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
APGMFHAH_03194 5.12e-112 ytrI - - - - - - -
APGMFHAH_03195 1.15e-39 - - - - - - - -
APGMFHAH_03196 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
APGMFHAH_03197 2.15e-63 ytpI - - S - - - YtpI-like protein
APGMFHAH_03198 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
APGMFHAH_03199 9.69e-164 yebC - - M - - - Membrane
APGMFHAH_03200 4.65e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
APGMFHAH_03201 1.97e-315 - - - S - - - Domain of unknown function (DUF4179)
APGMFHAH_03202 6.3e-111 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_03203 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
APGMFHAH_03204 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
APGMFHAH_03205 9.17e-285 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
APGMFHAH_03206 3.25e-225 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
APGMFHAH_03207 7.15e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APGMFHAH_03208 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_03209 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
APGMFHAH_03210 7.26e-204 yeaA - - S - - - Protein of unknown function (DUF4003)
APGMFHAH_03211 1.46e-201 - - - I - - - Alpha/beta hydrolase family
APGMFHAH_03212 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
APGMFHAH_03216 4.26e-220 - - - S - - - Alpha/beta hydrolase family
APGMFHAH_03217 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
APGMFHAH_03218 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
APGMFHAH_03219 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APGMFHAH_03220 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
APGMFHAH_03221 1.11e-237 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
APGMFHAH_03222 8.02e-84 ydfP - - S ko:K15977 - ko00000 DoxX
APGMFHAH_03223 3.11e-73 ydfQ - - CO - - - Thioredoxin
APGMFHAH_03224 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
APGMFHAH_03225 2.17e-38 - - - - - - - -
APGMFHAH_03227 6.22e-74 ydfR - - S - - - Protein of unknown function (DUF421)
APGMFHAH_03228 4.9e-36 ydfR - - S - - - Protein of unknown function (DUF421)
APGMFHAH_03229 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
APGMFHAH_03230 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
APGMFHAH_03231 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
APGMFHAH_03232 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
APGMFHAH_03233 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
APGMFHAH_03234 5.76e-70 - - - S - - - DoxX-like family
APGMFHAH_03235 8.04e-111 yycN - - K - - - Acetyltransferase
APGMFHAH_03236 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
APGMFHAH_03237 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
APGMFHAH_03238 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
APGMFHAH_03239 1.79e-267 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_03240 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
APGMFHAH_03243 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
APGMFHAH_03246 2.43e-14 - - - - - - - -
APGMFHAH_03247 5.08e-26 xkdM - - S - - - Phage tail tube protein
APGMFHAH_03249 1.89e-40 - - - - - - - -
APGMFHAH_03250 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
APGMFHAH_03251 1.18e-178 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_03252 1.41e-216 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
APGMFHAH_03253 1.56e-235 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03254 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
APGMFHAH_03255 7.88e-131 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
APGMFHAH_03256 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_03257 2.12e-65 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
APGMFHAH_03258 1.41e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
APGMFHAH_03259 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
APGMFHAH_03260 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
APGMFHAH_03261 9.56e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_03262 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_03263 8.23e-236 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
APGMFHAH_03264 3.24e-250 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
APGMFHAH_03265 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
APGMFHAH_03266 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
APGMFHAH_03267 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
APGMFHAH_03268 1.02e-202 yuxN - - K - - - Transcriptional regulator
APGMFHAH_03269 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_03270 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_03271 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APGMFHAH_03272 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
APGMFHAH_03273 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_03274 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
APGMFHAH_03275 1.26e-18 - - - - - - - -
APGMFHAH_03277 4.13e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
APGMFHAH_03279 2.94e-17 - - - EGP - - - Major Facilitator
APGMFHAH_03280 6.4e-09 - - - J - - - O-methyltransferase
APGMFHAH_03281 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
APGMFHAH_03282 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
APGMFHAH_03284 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
APGMFHAH_03285 3.48e-88 - - - S - - - YusW-like protein
APGMFHAH_03286 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
APGMFHAH_03287 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
APGMFHAH_03288 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
APGMFHAH_03289 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_03290 4.86e-84 yusQ - - S - - - Tautomerase enzyme
APGMFHAH_03291 0.0 yusP - - P - - - Major facilitator superfamily
APGMFHAH_03292 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
APGMFHAH_03293 8.66e-70 yusN - - M - - - Coat F domain
APGMFHAH_03294 2.23e-54 - - - - - - - -
APGMFHAH_03295 1.41e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
APGMFHAH_03296 1.11e-13 - - - S - - - YuzL-like protein
APGMFHAH_03297 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
APGMFHAH_03298 1.82e-276 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
APGMFHAH_03299 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
APGMFHAH_03300 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
APGMFHAH_03301 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
APGMFHAH_03302 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
APGMFHAH_03303 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
APGMFHAH_03304 8.14e-73 yusE - - CO - - - Thioredoxin
APGMFHAH_03305 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
APGMFHAH_03306 1.76e-235 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APGMFHAH_03307 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
APGMFHAH_03308 5.86e-189 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
APGMFHAH_03309 3.06e-60 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
APGMFHAH_03310 3.82e-183 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
APGMFHAH_03311 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
APGMFHAH_03312 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APGMFHAH_03313 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
APGMFHAH_03314 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
APGMFHAH_03315 1.78e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
APGMFHAH_03316 7.18e-86 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
APGMFHAH_03317 3.35e-56 - - - - - - - -
APGMFHAH_03319 2.63e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
APGMFHAH_03320 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
APGMFHAH_03321 2.24e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
APGMFHAH_03322 6.75e-306 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
APGMFHAH_03323 3.54e-199 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
APGMFHAH_03324 4.58e-215 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
APGMFHAH_03325 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
APGMFHAH_03326 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
APGMFHAH_03327 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_03328 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
APGMFHAH_03329 8.22e-98 ykzC - - S - - - Acetyltransferase (GNAT) family
APGMFHAH_03330 1.76e-190 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
APGMFHAH_03331 4.48e-35 ykzI - - - - - - -
APGMFHAH_03332 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
APGMFHAH_03333 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
APGMFHAH_03334 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
APGMFHAH_03335 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
APGMFHAH_03336 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APGMFHAH_03337 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APGMFHAH_03338 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APGMFHAH_03339 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APGMFHAH_03340 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
APGMFHAH_03341 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
APGMFHAH_03342 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
APGMFHAH_03343 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
APGMFHAH_03344 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
APGMFHAH_03345 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
APGMFHAH_03346 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
APGMFHAH_03347 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
APGMFHAH_03348 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
APGMFHAH_03349 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
APGMFHAH_03350 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
APGMFHAH_03351 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
APGMFHAH_03352 1.09e-18 - - - S - - - Uncharacterized protein YkpC
APGMFHAH_03353 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
APGMFHAH_03354 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
APGMFHAH_03355 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
APGMFHAH_03356 2.04e-47 - - - - - - - -
APGMFHAH_03357 3.63e-95 yugU - - S - - - Uncharacterised protein family UPF0047
APGMFHAH_03358 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
APGMFHAH_03359 2.52e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
APGMFHAH_03360 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
APGMFHAH_03361 2.16e-48 - - - - - - - -
APGMFHAH_03362 2.12e-70 mstX - - S - - - Membrane-integrating protein Mistic
APGMFHAH_03363 8.37e-232 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
APGMFHAH_03364 4.22e-95 yugN - - S - - - YugN-like family
APGMFHAH_03366 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
APGMFHAH_03367 2.17e-288 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
APGMFHAH_03368 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
APGMFHAH_03369 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
APGMFHAH_03370 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
APGMFHAH_03371 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
APGMFHAH_03372 6.74e-112 alaR - - K - - - Transcriptional regulator
APGMFHAH_03373 9.89e-201 yugF - - I - - - Hydrolase
APGMFHAH_03374 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
APGMFHAH_03375 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
APGMFHAH_03376 1.87e-98 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_03377 6.33e-150 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_03378 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
APGMFHAH_03379 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
APGMFHAH_03381 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
APGMFHAH_03382 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
APGMFHAH_03383 1.92e-97 yuxK - - S - - - protein conserved in bacteria
APGMFHAH_03384 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
APGMFHAH_03385 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
APGMFHAH_03386 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
APGMFHAH_03387 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
APGMFHAH_03388 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_03389 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
APGMFHAH_03390 1.71e-215 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
APGMFHAH_03391 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
APGMFHAH_03392 1.42e-21 - - - - - - - -
APGMFHAH_03393 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
APGMFHAH_03394 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APGMFHAH_03395 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APGMFHAH_03396 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APGMFHAH_03397 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APGMFHAH_03398 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
APGMFHAH_03399 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
APGMFHAH_03400 9.49e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
APGMFHAH_03401 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_03402 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_03404 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
APGMFHAH_03405 6.29e-10 - - - S - - - DegQ (SacQ) family
APGMFHAH_03407 8.73e-09 yuzC - - - - - - -
APGMFHAH_03408 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
APGMFHAH_03409 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
APGMFHAH_03410 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
APGMFHAH_03411 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
APGMFHAH_03412 1.63e-52 yueH - - S - - - YueH-like protein
APGMFHAH_03413 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
APGMFHAH_03414 1.35e-244 yueF - - S - - - transporter activity
APGMFHAH_03415 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
APGMFHAH_03416 1.19e-32 - - - S - - - Protein of unknown function (DUF2642)
APGMFHAH_03417 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
APGMFHAH_03418 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_03419 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
APGMFHAH_03420 0.0 yueB - - S - - - type VII secretion protein EsaA
APGMFHAH_03421 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
APGMFHAH_03422 4.75e-268 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
APGMFHAH_03423 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
APGMFHAH_03424 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
APGMFHAH_03425 1.03e-292 yukF - - QT - - - Transcriptional regulator
APGMFHAH_03426 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
APGMFHAH_03427 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
APGMFHAH_03428 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
APGMFHAH_03429 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
APGMFHAH_03430 2.59e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
APGMFHAH_03431 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
APGMFHAH_03432 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
APGMFHAH_03433 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
APGMFHAH_03434 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
APGMFHAH_03435 2.88e-141 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
APGMFHAH_03436 1.38e-123 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
APGMFHAH_03437 1.22e-277 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
APGMFHAH_03438 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
APGMFHAH_03439 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
APGMFHAH_03440 1.14e-255 yhjN - - S ko:K07120 - ko00000 membrane
APGMFHAH_03441 7.04e-270 - - - EGP - - - Transmembrane secretion effector
APGMFHAH_03442 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
APGMFHAH_03443 9.3e-102 yhjR - - S - - - Rubrerythrin
APGMFHAH_03444 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
APGMFHAH_03445 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
APGMFHAH_03446 1.34e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
APGMFHAH_03447 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
APGMFHAH_03448 6.4e-65 yisB - - V - - - COG1403 Restriction endonuclease
APGMFHAH_03449 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
APGMFHAH_03450 3.92e-86 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
APGMFHAH_03451 6.07e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
APGMFHAH_03452 6.73e-92 gerPC - - S ko:K06301 - ko00000 Spore germination protein
APGMFHAH_03453 1.76e-47 gerPB - - S ko:K06300 - ko00000 cell differentiation
APGMFHAH_03454 1.82e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
APGMFHAH_03455 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
APGMFHAH_03456 1.09e-221 cotH - - M ko:K06330 - ko00000 Spore Coat
APGMFHAH_03457 3.11e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
APGMFHAH_03458 1.02e-74 yisL - - S - - - UPF0344 protein
APGMFHAH_03459 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
APGMFHAH_03460 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
APGMFHAH_03461 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
APGMFHAH_03462 3.44e-142 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
APGMFHAH_03463 1.01e-310 yisQ - - V - - - Mate efflux family protein
APGMFHAH_03464 1.41e-207 yisR - - K - - - Transcriptional regulator
APGMFHAH_03465 8.71e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
APGMFHAH_03466 5.32e-242 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
APGMFHAH_03467 9.94e-120 yisT - - S - - - DinB family
APGMFHAH_03468 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
APGMFHAH_03469 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
APGMFHAH_03470 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
APGMFHAH_03471 5.29e-198 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
APGMFHAH_03472 9.64e-94 yitH - - K - - - Acetyltransferase (GNAT) domain
APGMFHAH_03473 7.23e-92 - - - S - - - Acetyltransferase (GNAT) domain
APGMFHAH_03474 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
APGMFHAH_03475 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
APGMFHAH_03476 2.75e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
APGMFHAH_03478 7.32e-49 yitR - - S - - - Domain of unknown function (DUF3784)
APGMFHAH_03479 1.45e-198 yitS - - S - - - protein conserved in bacteria
APGMFHAH_03480 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
APGMFHAH_03481 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
APGMFHAH_03482 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
APGMFHAH_03483 1.59e-243 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APGMFHAH_03484 1.81e-41 yazB - - K - - - transcriptional
APGMFHAH_03485 4.56e-115 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APGMFHAH_03486 1.09e-79 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APGMFHAH_03487 7.82e-204 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APGMFHAH_03488 8.89e-214 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
APGMFHAH_03489 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
APGMFHAH_03490 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APGMFHAH_03491 4.4e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
APGMFHAH_03492 5.93e-205 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
APGMFHAH_03493 7.84e-207 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
APGMFHAH_03494 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
APGMFHAH_03495 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APGMFHAH_03496 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
APGMFHAH_03497 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
APGMFHAH_03498 6.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
APGMFHAH_03499 9.3e-167 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
APGMFHAH_03500 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
APGMFHAH_03503 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
APGMFHAH_03504 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
APGMFHAH_03505 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
APGMFHAH_03506 1.91e-66 yabP - - S - - - Sporulation protein YabP
APGMFHAH_03507 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
APGMFHAH_03508 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
APGMFHAH_03509 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
APGMFHAH_03510 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
APGMFHAH_03511 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APGMFHAH_03512 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
APGMFHAH_03513 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
APGMFHAH_03514 2.77e-125 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
APGMFHAH_03515 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APGMFHAH_03516 2.47e-307 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
APGMFHAH_03517 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
APGMFHAH_03518 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
APGMFHAH_03519 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
APGMFHAH_03520 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
APGMFHAH_03521 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
APGMFHAH_03522 5.32e-53 veg - - S - - - protein conserved in bacteria
APGMFHAH_03523 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
APGMFHAH_03524 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
APGMFHAH_03525 6.3e-105 yfiV - - K - - - transcriptional
APGMFHAH_03526 1.49e-147 yfiU - - EGP - - - the major facilitator superfamily
APGMFHAH_03527 2.31e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
APGMFHAH_03528 1.25e-255 yfiS - - EGP - - - Major facilitator superfamily
APGMFHAH_03529 4.68e-138 yfiR - - K - - - Transcriptional regulator
APGMFHAH_03530 2.99e-249 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
APGMFHAH_03531 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
APGMFHAH_03532 1.28e-126 padR - - K - - - transcriptional
APGMFHAH_03533 7.56e-85 - - - J - - - Acetyltransferase (GNAT) domain
APGMFHAH_03534 1.23e-255 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
APGMFHAH_03535 1.15e-261 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
APGMFHAH_03536 2.17e-214 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_03537 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
APGMFHAH_03538 1.75e-245 baeS - - T - - - Histidine kinase
APGMFHAH_03539 1.18e-149 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
APGMFHAH_03540 1.93e-82 yfiD3 - - S - - - DoxX
APGMFHAH_03541 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
APGMFHAH_03542 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
APGMFHAH_03543 0.0 yobO - - M - - - COG5434 Endopolygalacturonase
APGMFHAH_03544 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_03545 8.69e-181 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
APGMFHAH_03546 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
APGMFHAH_03547 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
APGMFHAH_03548 1.94e-270 yfjB - - - - - - -
APGMFHAH_03549 1.02e-184 yfjC - - - - - - -
APGMFHAH_03550 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
APGMFHAH_03551 1e-105 - - - S - - - Family of unknown function (DUF5381)
APGMFHAH_03552 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
APGMFHAH_03553 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
APGMFHAH_03554 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
APGMFHAH_03555 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
APGMFHAH_03556 4.89e-264 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
APGMFHAH_03557 4.56e-243 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
APGMFHAH_03558 1.36e-244 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
APGMFHAH_03560 4.55e-109 yfjM - - S - - - Psort location Cytoplasmic, score
APGMFHAH_03561 7.83e-240 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APGMFHAH_03562 4.32e-59 - - - S - - - YfzA-like protein
APGMFHAH_03563 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APGMFHAH_03564 5.57e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APGMFHAH_03565 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
APGMFHAH_03566 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
APGMFHAH_03569 0.000711 - - - - - - - -
APGMFHAH_03575 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
APGMFHAH_03576 8.03e-81 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
APGMFHAH_03577 2.01e-267 acdA - - I - - - acyl-CoA dehydrogenase
APGMFHAH_03578 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
APGMFHAH_03579 1.82e-275 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
APGMFHAH_03580 3.3e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
APGMFHAH_03607 1.32e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
APGMFHAH_03608 0.0 yvrG - - T - - - Histidine kinase
APGMFHAH_03609 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
APGMFHAH_03610 6.67e-125 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
APGMFHAH_03611 3.46e-26 - - - S - - - YvrJ protein family
APGMFHAH_03612 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
APGMFHAH_03613 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
APGMFHAH_03614 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
APGMFHAH_03615 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_03616 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
APGMFHAH_03617 6.89e-190 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
APGMFHAH_03618 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03619 4.04e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03620 2.57e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
APGMFHAH_03622 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
APGMFHAH_03623 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
APGMFHAH_03624 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
APGMFHAH_03625 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
APGMFHAH_03626 8.87e-215 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
APGMFHAH_03627 1.27e-176 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
APGMFHAH_03628 1.43e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
APGMFHAH_03629 5.09e-200 yvgN - - S - - - reductase
APGMFHAH_03630 7.97e-113 yvgO - - - - - - -
APGMFHAH_03631 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
APGMFHAH_03632 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
APGMFHAH_03633 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APGMFHAH_03634 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
APGMFHAH_03635 3.88e-140 yvgT - - S - - - membrane
APGMFHAH_03636 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
APGMFHAH_03637 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
APGMFHAH_03638 8.95e-60 yfhJ - - S - - - WVELL protein
APGMFHAH_03639 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
APGMFHAH_03640 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
APGMFHAH_03641 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
APGMFHAH_03642 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
APGMFHAH_03643 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
APGMFHAH_03644 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
APGMFHAH_03645 2.26e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
APGMFHAH_03646 1.73e-48 yfhS - - - - - - -
APGMFHAH_03647 5.18e-171 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
APGMFHAH_03648 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
APGMFHAH_03649 2.01e-49 ygaB - - S - - - YgaB-like protein
APGMFHAH_03650 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
APGMFHAH_03651 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
APGMFHAH_03652 5.12e-236 ygaE - - S - - - Membrane
APGMFHAH_03653 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
APGMFHAH_03654 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
APGMFHAH_03655 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
APGMFHAH_03656 5.46e-74 ygzB - - S - - - UPF0295 protein
APGMFHAH_03657 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
APGMFHAH_03658 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APGMFHAH_03659 2.84e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
APGMFHAH_03660 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
APGMFHAH_03661 1.53e-56 yabA - - L - - - Involved in initiation control of chromosome replication
APGMFHAH_03662 5.2e-188 yaaT - - S - - - stage 0 sporulation protein
APGMFHAH_03663 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
APGMFHAH_03664 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
APGMFHAH_03665 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
APGMFHAH_03666 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
APGMFHAH_03667 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
APGMFHAH_03668 1.19e-258 yaaN - - P - - - Belongs to the TelA family
APGMFHAH_03669 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
APGMFHAH_03670 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
APGMFHAH_03671 5.37e-216 gspA - - M - - - General stress
APGMFHAH_03672 3.49e-158 ywaF - - S - - - Integral membrane protein
APGMFHAH_03673 1.25e-114 ywaE - - K - - - Transcriptional regulator
APGMFHAH_03674 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APGMFHAH_03675 9.14e-317 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
APGMFHAH_03676 5.3e-47 - - - - - - - -
APGMFHAH_03677 1.46e-264 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
APGMFHAH_03678 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
APGMFHAH_03679 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
APGMFHAH_03680 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APGMFHAH_03681 5.14e-161 yfmS - - NT - - - chemotaxis protein
APGMFHAH_03682 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
APGMFHAH_03683 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
APGMFHAH_03684 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
APGMFHAH_03685 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
APGMFHAH_03686 2.73e-242 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
APGMFHAH_03687 3.71e-281 yfnE - - S - - - Glycosyltransferase like family 2
APGMFHAH_03688 1.1e-228 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
APGMFHAH_03689 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
APGMFHAH_03690 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
APGMFHAH_03691 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
APGMFHAH_03692 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
APGMFHAH_03693 1.94e-248 yetN - - S - - - Protein of unknown function (DUF3900)
APGMFHAH_03694 5.94e-131 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
APGMFHAH_03695 1.3e-38 yetM - - CH - - - FAD binding domain
APGMFHAH_03696 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
APGMFHAH_03697 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
APGMFHAH_03698 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
APGMFHAH_03699 1.01e-217 yhcP - - - - - - -
APGMFHAH_03700 8.34e-128 yhcQ - - M - - - Spore coat protein
APGMFHAH_03701 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
APGMFHAH_03702 7.24e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
APGMFHAH_03703 1.67e-218 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
APGMFHAH_03704 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
APGMFHAH_03705 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
APGMFHAH_03706 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
APGMFHAH_03707 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
APGMFHAH_03708 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APGMFHAH_03709 1.08e-134 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
APGMFHAH_03710 6.65e-195 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
APGMFHAH_03711 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
APGMFHAH_03712 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APGMFHAH_03713 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
APGMFHAH_03714 2.56e-270 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
APGMFHAH_03715 1.15e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
APGMFHAH_03716 2.7e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
APGMFHAH_03717 1.65e-51 yhdB - - S - - - YhdB-like protein
APGMFHAH_03718 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
APGMFHAH_03719 4.06e-271 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
APGMFHAH_03720 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
APGMFHAH_03721 1.51e-306 ygxB - - M - - - Conserved TM helix
APGMFHAH_03722 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
APGMFHAH_03724 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
APGMFHAH_03725 2.51e-39 yjzC - - S - - - YjzC-like protein
APGMFHAH_03726 1.53e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
APGMFHAH_03727 2.42e-182 yjaU - - I - - - carboxylic ester hydrolase activity
APGMFHAH_03728 6.08e-131 yjaV - - - - - - -
APGMFHAH_03729 3.7e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
APGMFHAH_03730 2.98e-13 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
APGMFHAH_03731 2.67e-38 yjzB - - - - - - -
APGMFHAH_03732 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APGMFHAH_03733 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
APGMFHAH_03734 9.48e-193 yjaZ - - O - - - Zn-dependent protease
APGMFHAH_03735 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_03736 2.07e-237 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_03737 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
APGMFHAH_03738 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APGMFHAH_03739 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APGMFHAH_03740 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
APGMFHAH_03741 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
APGMFHAH_03742 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
APGMFHAH_03743 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APGMFHAH_03744 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
APGMFHAH_03745 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_03746 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
APGMFHAH_03747 1.43e-268 yjbB - - EGP - - - Major Facilitator Superfamily
APGMFHAH_03748 8.88e-132 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APGMFHAH_03749 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
APGMFHAH_03750 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
APGMFHAH_03751 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
APGMFHAH_03752 1.78e-281 coiA - - S ko:K06198 - ko00000 Competence protein
APGMFHAH_03753 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
APGMFHAH_03754 2.68e-28 - - - - - - - -
APGMFHAH_03756 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
APGMFHAH_03757 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
APGMFHAH_03758 1.03e-121 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
APGMFHAH_03759 7.02e-128 yjbK - - S - - - protein conserved in bacteria
APGMFHAH_03760 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
APGMFHAH_03761 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
APGMFHAH_03762 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
APGMFHAH_03763 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
APGMFHAH_03764 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
APGMFHAH_03765 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
APGMFHAH_03766 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APGMFHAH_03767 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
APGMFHAH_03768 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
APGMFHAH_03769 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
APGMFHAH_03770 2.17e-170 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
APGMFHAH_03771 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
APGMFHAH_03772 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
APGMFHAH_03773 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
APGMFHAH_03774 2.09e-103 yjbX - - S - - - Spore coat protein
APGMFHAH_03775 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
APGMFHAH_03776 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
APGMFHAH_03777 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
APGMFHAH_03778 1.51e-18 cotW - - - ko:K06341 - ko00000 -
APGMFHAH_03780 5.03e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
APGMFHAH_03783 1.88e-52 spoVIF - - S - - - Stage VI sporulation protein F
APGMFHAH_03784 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
APGMFHAH_03785 5.19e-50 - - - - - - - -
APGMFHAH_03786 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
APGMFHAH_03787 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
APGMFHAH_03788 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
APGMFHAH_03789 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
APGMFHAH_03790 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
APGMFHAH_03791 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
APGMFHAH_03793 3.69e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
APGMFHAH_03794 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
APGMFHAH_03795 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_03796 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
APGMFHAH_03797 6.19e-39 ywdA - - - - - - -
APGMFHAH_03798 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
APGMFHAH_03799 5.46e-191 ywdF - - S - - - Glycosyltransferase like family 2
APGMFHAH_03800 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
APGMFHAH_03801 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
APGMFHAH_03802 1.08e-63 ywdI - - S - - - Family of unknown function (DUF5327)
APGMFHAH_03803 4.38e-302 ywdJ - - F - - - Xanthine uracil
APGMFHAH_03804 1.59e-78 ywdK - - S - - - small membrane protein
APGMFHAH_03808 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APGMFHAH_03809 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
APGMFHAH_03810 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
APGMFHAH_03811 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
APGMFHAH_03812 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APGMFHAH_03813 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
APGMFHAH_03814 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
APGMFHAH_03815 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
APGMFHAH_03816 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
APGMFHAH_03817 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
APGMFHAH_03818 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
APGMFHAH_03819 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
APGMFHAH_03820 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
APGMFHAH_03821 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
APGMFHAH_03823 1.17e-148 - - - - - - - -
APGMFHAH_03824 5.53e-175 - - - - - - - -
APGMFHAH_03825 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
APGMFHAH_03826 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
APGMFHAH_03827 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
APGMFHAH_03828 4.95e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
APGMFHAH_03829 8.88e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
APGMFHAH_03830 6.04e-227 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APGMFHAH_03831 1.94e-168 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
APGMFHAH_03832 1.47e-202 ydjI - - S - - - virion core protein (lumpy skin disease virus)
APGMFHAH_03833 4.59e-247 - - - S - - - Ion transport 2 domain protein
APGMFHAH_03834 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
APGMFHAH_03835 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
APGMFHAH_03836 1.79e-84 ydjM - - M - - - Lytic transglycolase
APGMFHAH_03837 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
APGMFHAH_03838 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
APGMFHAH_03839 3.26e-72 - - - L - - - transposase activity
APGMFHAH_03841 3.69e-189 yfkD - - S - - - YfkD-like protein
APGMFHAH_03842 1.34e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
APGMFHAH_03843 4.31e-162 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_03844 2.02e-76 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_03845 1.64e-12 - - - - - - - -
APGMFHAH_03846 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
APGMFHAH_03847 1.03e-66 yfkI - - S - - - gas vesicle protein
APGMFHAH_03848 9.78e-107 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APGMFHAH_03849 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
APGMFHAH_03850 5.94e-264 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
APGMFHAH_03851 1.83e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
APGMFHAH_03852 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
APGMFHAH_03853 6.16e-160 frp - - C - - - nitroreductase
APGMFHAH_03854 5.05e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
APGMFHAH_03855 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
APGMFHAH_03856 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_03857 1.36e-32 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
APGMFHAH_03858 0.0 yflA - - E ko:K03310 - ko00000 Sodium alanine symporter
APGMFHAH_03859 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
APGMFHAH_03860 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
APGMFHAH_03861 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
APGMFHAH_03862 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
APGMFHAH_03863 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
APGMFHAH_03864 6.9e-27 yflI - - - - - - -
APGMFHAH_03865 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
APGMFHAH_03866 3.42e-157 yflK - - S - - - protein conserved in bacteria
APGMFHAH_03867 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
APGMFHAH_03868 5.59e-275 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
APGMFHAH_03869 2.82e-191 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
APGMFHAH_03870 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
APGMFHAH_03871 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
APGMFHAH_03872 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
APGMFHAH_03873 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
APGMFHAH_03874 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
APGMFHAH_03875 7.03e-307 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
APGMFHAH_03876 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
APGMFHAH_03877 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
APGMFHAH_03878 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
APGMFHAH_03879 3.18e-218 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03880 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03881 1.4e-192 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
APGMFHAH_03882 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
APGMFHAH_03883 2.45e-268 yfhI - - EGP - - - -transporter
APGMFHAH_03885 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
APGMFHAH_03886 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
APGMFHAH_03887 1.88e-220 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
APGMFHAH_03889 8.86e-35 yfhD - - S - - - YfhD-like protein
APGMFHAH_03890 1.17e-137 yfhC - - C - - - nitroreductase
APGMFHAH_03891 3.1e-214 yfhB - - S - - - PhzF family
APGMFHAH_03892 1.05e-228 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03893 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APGMFHAH_03894 1.28e-229 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
APGMFHAH_03895 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
APGMFHAH_03896 1.58e-36 - - - - - - - -
APGMFHAH_03897 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
APGMFHAH_03898 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
APGMFHAH_03900 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
APGMFHAH_03901 7.4e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
APGMFHAH_03902 2.79e-213 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
APGMFHAH_03903 1.09e-185 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
APGMFHAH_03904 1.89e-275 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
APGMFHAH_03906 2.75e-59 ygaO - - - - - - -
APGMFHAH_03907 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_03909 1.07e-144 yhzB - - S - - - B3/4 domain
APGMFHAH_03910 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APGMFHAH_03911 9.27e-224 yhbB - - S - - - Putative amidase domain
APGMFHAH_03912 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
APGMFHAH_03913 3.73e-133 yhbD - - K - - - Protein of unknown function (DUF4004)
APGMFHAH_03914 1.25e-93 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
APGMFHAH_03915 3.01e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
APGMFHAH_03916 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
APGMFHAH_03917 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
APGMFHAH_03918 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
APGMFHAH_03919 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
APGMFHAH_03920 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
APGMFHAH_03921 4.87e-128 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
APGMFHAH_03922 3.95e-59 yhcC - - - - - - -
APGMFHAH_03923 8.31e-69 - - - - - - - -
APGMFHAH_03924 1.67e-79 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
APGMFHAH_03925 1.54e-154 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_03926 1.25e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
APGMFHAH_03927 9.87e-212 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
APGMFHAH_03928 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
APGMFHAH_03929 6.12e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
APGMFHAH_03930 4.37e-131 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
APGMFHAH_03931 3e-71 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
APGMFHAH_03932 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
APGMFHAH_03933 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
APGMFHAH_03934 1.5e-81 - - - S - - - Immunity protein 70
APGMFHAH_03935 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
APGMFHAH_03936 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
APGMFHAH_03937 3.19e-111 yddI - - - - - - -
APGMFHAH_03938 1.03e-237 yddH - - M - - - Lysozyme-like
APGMFHAH_03939 0.0 yddG - - S - - - maturation of SSU-rRNA
APGMFHAH_03940 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
APGMFHAH_03941 2.21e-242 yddE - - S - - - AAA-like domain
APGMFHAH_03942 2.61e-269 yddE - - S - - - AAA-like domain
APGMFHAH_03943 6.91e-118 yddD - - S - - - TcpE family
APGMFHAH_03944 9.78e-54 yddC - - - - - - -
APGMFHAH_03945 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
APGMFHAH_03947 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
APGMFHAH_03948 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
APGMFHAH_03949 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
APGMFHAH_03950 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
APGMFHAH_03951 0.0 ylaA - - - - - - -
APGMFHAH_03952 1.44e-56 ylaB - - - - - - -
APGMFHAH_03953 2.41e-113 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
APGMFHAH_03955 3.25e-55 ylaE - - - - - - -
APGMFHAH_03956 6.35e-30 - - - S - - - Family of unknown function (DUF5325)
APGMFHAH_03957 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
APGMFHAH_03958 4.4e-63 ylaH - - S - - - YlaH-like protein
APGMFHAH_03959 8.92e-44 ylaI - - S - - - protein conserved in bacteria
APGMFHAH_03960 2e-125 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
APGMFHAH_03961 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
APGMFHAH_03962 2.67e-111 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
APGMFHAH_03963 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
APGMFHAH_03964 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
APGMFHAH_03965 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
APGMFHAH_03966 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
APGMFHAH_03967 2.44e-213 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
APGMFHAH_03968 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
APGMFHAH_03969 2.28e-250 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
APGMFHAH_03970 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APGMFHAH_03971 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
APGMFHAH_03972 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
APGMFHAH_03973 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
APGMFHAH_03974 1.61e-81 ylbA - - S - - - YugN-like family
APGMFHAH_03975 1.53e-97 ylbB - - T - - - COG0517 FOG CBS domain
APGMFHAH_03976 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
APGMFHAH_03977 3.78e-88 ylbD - - S - - - Putative coat protein
APGMFHAH_03978 1.73e-48 ylbE - - S - - - YlbE-like protein
APGMFHAH_03979 6.27e-67 yerC - - S - - - protein conserved in bacteria
APGMFHAH_03980 2.63e-241 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
APGMFHAH_03981 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
APGMFHAH_03982 3.3e-35 - - - S - - - Protein of unknown function (DUF2892)
APGMFHAH_03983 5.84e-292 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
APGMFHAH_03984 1.06e-95 - - - K - - - helix_turn_helix ASNC type
APGMFHAH_03985 5.69e-298 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
APGMFHAH_03986 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
APGMFHAH_03987 8.88e-138 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APGMFHAH_03988 1.71e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
APGMFHAH_03989 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APGMFHAH_03990 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APGMFHAH_03991 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APGMFHAH_03992 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APGMFHAH_03993 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
APGMFHAH_03994 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APGMFHAH_03995 1.24e-276 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APGMFHAH_03996 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APGMFHAH_03997 3.13e-38 yebG - - S - - - NETI protein
APGMFHAH_03998 2.66e-120 yebE - - S - - - UPF0316 protein
APGMFHAH_04000 1.02e-35 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
APGMFHAH_04001 1.69e-45 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
APGMFHAH_04002 6.42e-147 ydgI - - C - - - nitroreductase
APGMFHAH_04003 1.9e-89 - - - K - - - Winged helix DNA-binding domain
APGMFHAH_04004 7.37e-154 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
APGMFHAH_04005 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
APGMFHAH_04006 2.66e-150 ydhC - - K - - - FCD
APGMFHAH_04007 4.21e-121 ydhD - - M - - - Glycosyl hydrolase
APGMFHAH_04008 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
APGMFHAH_04009 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APGMFHAH_04010 3.41e-183 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
APGMFHAH_04011 7.77e-283 yabE - - T - - - protein conserved in bacteria
APGMFHAH_04012 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
APGMFHAH_04013 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
APGMFHAH_04020 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
APGMFHAH_04021 4.36e-52 ylbG - - S - - - UPF0298 protein
APGMFHAH_04022 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
APGMFHAH_04023 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APGMFHAH_04024 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
APGMFHAH_04025 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
APGMFHAH_04026 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
APGMFHAH_04027 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
APGMFHAH_04029 6.94e-117 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
APGMFHAH_04030 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
APGMFHAH_04031 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
APGMFHAH_04032 1.33e-115 ylbP - - K - - - n-acetyltransferase
APGMFHAH_04033 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APGMFHAH_04034 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
APGMFHAH_04035 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
APGMFHAH_04036 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
APGMFHAH_04037 3.42e-68 ftsL - - D - - - Essential cell division protein
APGMFHAH_04038 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
APGMFHAH_04039 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
APGMFHAH_04040 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APGMFHAH_04041 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APGMFHAH_04042 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
APGMFHAH_04043 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
APGMFHAH_04044 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
APGMFHAH_04045 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
APGMFHAH_04046 1.37e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
APGMFHAH_04047 3.45e-146 ylxW - - S - - - protein conserved in bacteria
APGMFHAH_04048 8.67e-132 ylxX - - S - - - protein conserved in bacteria
APGMFHAH_04049 5.37e-76 sbp - - S - - - small basic protein
APGMFHAH_04050 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
APGMFHAH_04051 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APGMFHAH_04052 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
APGMFHAH_04054 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
APGMFHAH_04055 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_04056 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APGMFHAH_04057 6.37e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
APGMFHAH_04058 5.57e-174 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
APGMFHAH_04059 1.12e-65 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
APGMFHAH_04060 3.58e-51 ylmC - - S - - - sporulation protein
APGMFHAH_04061 9.17e-204 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
APGMFHAH_04062 9.03e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APGMFHAH_04063 1.28e-86 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
APGMFHAH_04064 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
APGMFHAH_04065 5e-177 ylmH - - S - - - conserved protein, contains S4-like domain
APGMFHAH_04066 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
APGMFHAH_04067 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
APGMFHAH_04068 6.98e-279 - - - L - - - Transposase
APGMFHAH_04069 4.78e-152 - - - L - - - Bacterial dnaA protein
APGMFHAH_04070 5.6e-173 - - - L - - - Integrase core domain
APGMFHAH_04071 7.55e-59 orfX1 - - L - - - Transposase
APGMFHAH_04072 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
APGMFHAH_04073 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
APGMFHAH_04074 3.04e-59 cgeC - - - ko:K06321 - ko00000 -
APGMFHAH_04075 3.62e-82 cgeA - - - ko:K06319 - ko00000 -
APGMFHAH_04076 4.45e-226 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
APGMFHAH_04077 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
APGMFHAH_04078 1.66e-157 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
APGMFHAH_04079 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
APGMFHAH_04080 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APGMFHAH_04081 4.14e-94 ypoP - - K - - - transcriptional
APGMFHAH_04082 2.35e-288 mepA - - V - - - MATE efflux family protein
APGMFHAH_04083 8.69e-40 ypmT - - S - - - Uncharacterized ympT
APGMFHAH_04084 5.59e-128 ypmS - - S - - - protein conserved in bacteria
APGMFHAH_04085 2.78e-175 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
APGMFHAH_04086 1.24e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
APGMFHAH_04087 2.12e-53 ypmP - - S - - - Protein of unknown function (DUF2535)
APGMFHAH_04088 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
APGMFHAH_04089 5.47e-234 yplP - - K - - - Transcriptional regulator
APGMFHAH_04090 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
APGMFHAH_04091 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
APGMFHAH_04092 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APGMFHAH_04093 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
APGMFHAH_04094 2.01e-147 ypjP - - S - - - YpjP-like protein
APGMFHAH_04095 2.31e-182 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
APGMFHAH_04096 2.78e-98 yphP - - S - - - Belongs to the UPF0403 family
APGMFHAH_04097 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
APGMFHAH_04098 6.9e-27 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_04099 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
APGMFHAH_04100 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APGMFHAH_04101 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
APGMFHAH_04102 1.16e-102 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
APGMFHAH_04103 8.13e-235 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
APGMFHAH_04104 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
APGMFHAH_04105 5.77e-213 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
APGMFHAH_04106 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
APGMFHAH_04107 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
APGMFHAH_04108 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
APGMFHAH_04109 3.25e-137 - - - L - - - DNA ligase (ATP) activity
APGMFHAH_04111 1.13e-64 - - - L - - - DNA ligase (ATP) activity
APGMFHAH_04112 1.15e-115 - - - S - - - DinB family
APGMFHAH_04116 5.03e-53 ydcL - - L - - - Belongs to the 'phage' integrase family
APGMFHAH_04118 4.39e-37 yddA - - - - - - -
APGMFHAH_04121 1.63e-07 - - - L - - - COG2963 Transposase and inactivated derivatives
APGMFHAH_04122 3.57e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
APGMFHAH_04123 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
APGMFHAH_04124 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
APGMFHAH_04125 4.48e-161 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
APGMFHAH_04127 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
APGMFHAH_04128 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
APGMFHAH_04129 1.76e-283 yfkA - - S - - - YfkB-like domain
APGMFHAH_04130 3.26e-36 yfjT - - - - - - -
APGMFHAH_04131 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
APGMFHAH_04132 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
APGMFHAH_04136 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
APGMFHAH_04139 2.71e-103 yjoA - - S - - - DinB family
APGMFHAH_04140 8.36e-81 VCP - - O - - - AAA domain (dynein-related subfamily)

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)