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ORF_ID	e_value	Gene_name	EC_number	CAZy	COGs	KEGG_ko	KEGG_Pathway	BRITE	Description
IPFFCMEA_00001	3.99e-53	-	-	-	-	-	-	-	-
IPFFCMEA_00003	1.07e-57	-	-	-	S	-	-	-	transposition, DNA-mediated
IPFFCMEA_00004	6.23e-148	-	-	-	S	-	-	-	HTH-like domain
IPFFCMEA_00005	0.0	-	-	-	L	-	-	-	AAA ATPase domain
IPFFCMEA_00006	0.0	-	-	-	L	-	-	-	Superfamily I DNA and RNA helicases
IPFFCMEA_00007	0.0	-	-	-	V	-	-	-	Abi-like protein
IPFFCMEA_00008	6.83e-45	-	-	-	-	-	-	-	-
IPFFCMEA_00009	3.84e-87	res	-	-	L	-	-	-	Resolvase, N terminal domain
IPFFCMEA_00010	6.97e-98	-	3.1.21.3	-	L	ko:K01154	-	ko00000,ko01000,ko02048	Type I restriction modification DNA specificity domain
IPFFCMEA_00011	0.0	hsdM	2.1.1.72	-	V	ko:K03427	-	ko00000,ko01000,ko02048	Type I restriction-modification system
IPFFCMEA_00012	0.0	hsdR	3.1.21.3	-	L	ko:K01153	-	ko00000,ko01000,ko02048	COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
IPFFCMEA_00015	3.17e-170	-	-	-	L	-	-	-	Phage integrase family
IPFFCMEA_00017	4.05e-119	ysnB	-	-	S	ko:K07095	-	ko00000	Phosphoesterase
IPFFCMEA_00018	3.05e-132	rdgB	3.6.1.66	-	F	ko:K02428	ko00230,map00230	ko00000,ko00001,ko01000	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IPFFCMEA_00019	4.12e-170	rph	2.7.7.56	-	J	ko:K00989	-	ko00000,ko01000,ko03016	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IPFFCMEA_00020	8.03e-256	gerM	-	-	S	ko:K06298	-	ko00000	COG5401 Spore germination protein
IPFFCMEA_00021	1.15e-196	murI	3.6.1.66, 5.1.1.3	-	M	ko:K01776,ko:K02428	ko00230,ko00471,ko01100,map00230,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IPFFCMEA_00022	1.6e-98	ysmB	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPFFCMEA_00023	1.81e-41	gerE	-	-	K	ko:K01994	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00024	1.26e-100	ysmA	-	-	S	ko:K07107	-	ko00000,ko01000	thioesterase
IPFFCMEA_00025	1.15e-189	sdhB	1.3.5.1, 1.3.5.4	-	C	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IPFFCMEA_00026	0.0	sdhA	1.3.5.1, 1.3.5.4	-	C	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	ko00000,ko00001,ko00002,ko01000	succinate dehydrogenase
IPFFCMEA_00027	1.35e-140	sdhC	-	-	C	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002	succinate dehydrogenase
IPFFCMEA_00028	8.53e-104	yslB	-	-	S	-	-	-	Protein of unknown function (DUF2507)
IPFFCMEA_00029	1.13e-274	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IPFFCMEA_00030	0.0	uvrC	-	-	L	ko:K03703	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IPFFCMEA_00031	1.12e-69	trxA	-	-	O	ko:K03671	ko04621,ko05418,map04621,map05418	ko00000,ko00001,ko03110	Belongs to the thioredoxin family
IPFFCMEA_00032	0.0	xsa	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	Alpha-L-arabinofuranosidase C-terminus
IPFFCMEA_00034	5e-227	etfA	-	-	C	ko:K03522	-	ko00000,ko04147	Electron transfer flavoprotein
IPFFCMEA_00035	2.58e-179	etfB	-	-	C	ko:K03521	-	ko00000	Electron transfer flavoprotein
IPFFCMEA_00036	5.17e-175	fadB	4.2.1.17	-	I	ko:K13767	ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the enoyl-CoA hydratase isomerase family
IPFFCMEA_00037	5.74e-129	fadR	-	-	K	ko:K13770	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00038	0.0	lcfA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPFFCMEA_00039	3.76e-89	yshE	-	-	S	ko:K08989	-	ko00000	membrane
IPFFCMEA_00040	0.0	mutS2	-	-	L	ko:K07456	ko03430,map03430	ko00000,ko00001,ko03400	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IPFFCMEA_00041	0.0	polX	-	-	L	ko:K02347	-	ko00000,ko03400	COG1796 DNA polymerase IV (family X)
IPFFCMEA_00042	1.09e-111	yshB	-	-	S	-	-	-	membrane protein, required for colicin V production
IPFFCMEA_00043	1.04e-54	zapA	-	-	D	ko:K09888	-	ko00000,ko03036	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IPFFCMEA_00044	8.48e-215	rnhC	3.1.26.4	-	L	ko:K03471	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPFFCMEA_00045	0.0	pheT	6.1.1.20	-	J	ko:K01890	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPFFCMEA_00046	7.36e-250	pheS	6.1.1.20	-	J	ko:K01889	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPFFCMEA_00047	7.68e-172	spoU	-	-	J	ko:K03437	-	ko00000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPFFCMEA_00048	7.54e-44	sspI	-	-	S	ko:K06426	-	ko00000	Belongs to the SspI family
IPFFCMEA_00049	3.19e-263	cdaR_1	-	-	KT	ko:K02647	-	ko00000,ko03000	regulator
IPFFCMEA_00050	0.0	glcD	1.1.3.15	-	C	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001,ko01000	Glycolate oxidase subunit
IPFFCMEA_00051	0.0	glcF	-	-	C	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	ko00000,ko00001	Glycolate oxidase
IPFFCMEA_00052	8.42e-69	-	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase-like domain
IPFFCMEA_00053	0.0	cstA	-	-	T	ko:K06200	-	ko00000	Carbon starvation protein
IPFFCMEA_00054	0.0	abfA	3.2.1.55	GH51	G	ko:K01209	ko00520,map00520	ko00000,ko00001,ko01000	alpha-L-arabinofuranosidase activity
IPFFCMEA_00055	4.28e-190	araQ	-	-	G	ko:K17236	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport system permease
IPFFCMEA_00056	7.9e-218	araP	-	-	G	ko:K17235	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IPFFCMEA_00057	0.0	araN	-	-	G	ko:K17234	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	carbohydrate transport
IPFFCMEA_00058	3.05e-281	araM	1.1.1.261	-	I	ko:K00096	ko00564,map00564	ko00000,ko00001,ko01000	Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IPFFCMEA_00059	2.52e-61	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IPFFCMEA_00060	1.46e-87	araL	-	-	G	ko:K02101	-	ko00000	Haloacid dehalogenase-like hydrolase
IPFFCMEA_00061	1.7e-170	araD	5.1.3.4	-	G	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IPFFCMEA_00062	0.0	araB	2.7.1.16	-	C	ko:K00853	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Belongs to the ribulokinase family
IPFFCMEA_00063	0.0	araA	5.3.1.4	-	G	ko:K01804	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of L-arabinose to L-ribulose
IPFFCMEA_00064	4.56e-241	-	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IPFFCMEA_00065	3.57e-261	ysdC	-	-	G	-	-	-	COG1363 Cellulase M and related proteins
IPFFCMEA_00066	1.96e-89	ysdB	-	-	S	-	-	-	Sigma-w pathway protein YsdB
IPFFCMEA_00067	3.65e-59	ysdA	-	-	S	-	-	-	Membrane
IPFFCMEA_00068	3.26e-76	rplT	-	-	J	ko:K02887	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IPFFCMEA_00069	3.93e-37	rpmI	-	-	J	ko:K02916	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL35 family
IPFFCMEA_00070	1.81e-111	infC	-	-	J	ko:K02520	-	ko00000,ko03012,ko03029	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPFFCMEA_00072	1.53e-149	lrgB	-	-	M	ko:K05339	ko02020,map02020	ko00000,ko00001	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IPFFCMEA_00073	8.47e-85	lrgA	-	-	S	ko:K05338	ko02020,map02020	ko00000,ko00001,ko02000	Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IPFFCMEA_00074	1.96e-166	lytT	-	-	T	ko:K07705	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG3279 Response regulator of the LytR AlgR family
IPFFCMEA_00075	0.0	lytS	2.7.13.3	-	T	ko:K07704	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_00076	1.98e-189	ysaA	3.1.3.5, 3.8.1.2	-	S	ko:K01560,ko:K07025,ko:K08723	ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120	ko00000,ko00001,ko01000	HAD-hyrolase-like
IPFFCMEA_00077	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPFFCMEA_00079	2e-204	ytxC	-	-	S	-	-	-	YtxC-like family
IPFFCMEA_00080	9.77e-144	ytxB	-	-	S	-	-	-	SNARE associated Golgi protein
IPFFCMEA_00081	1.22e-220	dnaI	-	-	L	ko:K11144	-	ko00000,ko03032	Primosomal protein DnaI
IPFFCMEA_00082	0.0	dnaB	-	-	L	ko:K03346	-	ko00000,ko03032	Membrane attachment protein
IPFFCMEA_00083	2.42e-105	nrdR	-	-	K	ko:K07738	-	ko00000,ko03000	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPFFCMEA_00084	2.42e-88	speH	4.1.1.50	-	E	ko:K01611	ko00270,ko00330,ko01100,map00270,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IPFFCMEA_00085	9.99e-246	gapB	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPFFCMEA_00086	1.15e-86	ytcD	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00087	1.6e-254	ytbD	-	-	EGP	ko:K19577	-	ko00000,ko02000	-transporter
IPFFCMEA_00088	4.54e-205	ytbE	-	-	S	-	-	-	reductase
IPFFCMEA_00089	1.63e-125	coaE	2.7.1.24	-	F	ko:K00859	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IPFFCMEA_00090	1.68e-138	ytaF	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IPFFCMEA_00091	4.73e-201	fpg	3.2.2.23, 4.2.99.18	-	L	ko:K10563	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IPFFCMEA_00092	0.0	polA	2.7.7.7	-	L	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	ko00000,ko00001,ko01000,ko03032,ko03400	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPFFCMEA_00093	0.0	phoR	2.7.13.3	-	T	ko:K07636	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase
IPFFCMEA_00094	1.62e-169	phoP	-	-	T	ko:K07658	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_00095	6.01e-217	mdh	1.1.1.27, 1.1.1.37	-	C	ko:K00016,ko:K00024	ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible oxidation of malate to oxaloacetate
IPFFCMEA_00096	2.28e-309	icd	1.1.1.42	-	C	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	br01601,ko00000,ko00001,ko00002,ko01000	isocitrate
IPFFCMEA_00097	3.2e-265	citZ	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IPFFCMEA_00098	0.0	ytcJ	-	-	S	-	-	-	amidohydrolase
IPFFCMEA_00099	0.0	ytcI	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IPFFCMEA_00100	5.88e-38	-	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IPFFCMEA_00101	2.55e-288	thiI	2.8.1.4	-	H	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPFFCMEA_00102	1.59e-265	iscS2	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IPFFCMEA_00103	1.17e-304	braB	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IPFFCMEA_00104	0.0	ezrA	-	-	D	ko:K06286	-	ko00000,ko03036	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IPFFCMEA_00105	1.07e-197	hisK	3.1.3.15	-	E	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IPFFCMEA_00106	9.83e-141	yttP	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00107	1.95e-114	ytsP	1.8.4.14	-	T	ko:K08968	ko00270,map00270	ko00000,ko00001,ko01000	GAF domain-containing protein
IPFFCMEA_00108	0.0	ytrP	-	-	T	-	-	-	COG2199 FOG GGDEF domain
IPFFCMEA_00109	2.01e-141	rpsD	-	-	J	ko:K02986	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPFFCMEA_00111	5.31e-303	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPFFCMEA_00112	0.0	acsA	6.2.1.1	-	I	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko01004	COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IPFFCMEA_00113	3.46e-156	acuA	-	-	K	ko:K04766	-	ko00000,ko01000	Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IPFFCMEA_00114	1.45e-150	acuB	-	-	S	ko:K04767	-	ko00000	Domain in cystathionine beta-synthase and other proteins.
IPFFCMEA_00115	2.58e-290	acuC	-	-	BQ	ko:K04768	-	ko00000	histone deacetylase
IPFFCMEA_00116	1.6e-161	ytxE	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IPFFCMEA_00117	1.18e-187	motP	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IPFFCMEA_00118	4.16e-235	ccpA	-	-	K	ko:K02529	-	ko00000,ko03000	catabolite control protein A
IPFFCMEA_00119	7.64e-250	aroA	2.5.1.54, 5.4.99.5	-	E	ko:K03856,ko:K13853	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IPFFCMEA_00120	6.39e-71	ytxJ	-	-	O	-	-	-	Protein of unknown function (DUF2847)
IPFFCMEA_00121	3.17e-30	ytxH	-	-	S	-	-	-	COG4980 Gas vesicle protein
IPFFCMEA_00122	1.67e-63	ytxG	-	-	S	-	-	-	protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IPFFCMEA_00123	0.0	murC	6.3.2.8	-	M	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Belongs to the MurCDEF family
IPFFCMEA_00124	0.0	sftA	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IPFFCMEA_00125	7.25e-140	ytpR	-	-	J	ko:K06878	-	ko00000	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IPFFCMEA_00126	1.02e-191	ytpQ	-	-	S	-	-	-	Belongs to the UPF0354 family
IPFFCMEA_00127	3.17e-75	ytpP	-	-	CO	-	-	-	Thioredoxin
IPFFCMEA_00128	4.89e-63	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IPFFCMEA_00129	4.88e-29	ytoQ	-	-	S	-	-	-	Nucleoside 2-deoxyribosyltransferase YtoQ
IPFFCMEA_00130	3.71e-261	pepA	3.4.11.7	-	G	ko:K01261,ko:K01269	-	ko00000,ko01000,ko01002	COG1363 Cellulase M and related proteins
IPFFCMEA_00131	1.17e-67	ytzB	-	-	S	-	-	-	small secreted protein
IPFFCMEA_00132	0.0	malS	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IPFFCMEA_00133	3.05e-190	ytnP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPFFCMEA_00134	2.52e-155	trmB	2.1.1.33	-	J	ko:K03439	-	ko00000,ko01000,ko03016	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IPFFCMEA_00135	9.51e-61	ytzH	-	-	S	-	-	-	YtzH-like protein
IPFFCMEA_00136	3.02e-192	ytmP	-	-	M	-	-	-	Phosphotransferase
IPFFCMEA_00137	0.0	amyX	3.2.1.41	CBM48,GH13	G	ko:K01200	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 13 family
IPFFCMEA_00138	2.22e-231	ytlR	-	-	I	-	-	-	Diacylglycerol kinase catalytic domain
IPFFCMEA_00139	9.92e-212	ytlQ	-	-	-	-	-	-	-
IPFFCMEA_00140	1.5e-130	ytlP	3.1.4.58	-	J	ko:K01975	-	ko00000,ko01000,ko03016	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IPFFCMEA_00141	6.05e-221	ytkP	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IPFFCMEA_00142	0.0	ytjP	3.5.1.18	-	E	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Dipeptidase
IPFFCMEA_00143	7.02e-288	pbuO	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IPFFCMEA_00144	1.12e-252	ythQ	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	Bacterial ABC transporter protein EcsB
IPFFCMEA_00145	8.04e-168	ythP	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IPFFCMEA_00146	4.46e-46	ytzE	-	-	K	-	-	-	COG1349 Transcriptional regulators of sugar metabolism
IPFFCMEA_00147	7.43e-170	rsuA	5.4.99.19	-	J	ko:K06183	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IPFFCMEA_00148	0.0	ytgP	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPFFCMEA_00149	6.99e-294	ytfP	-	-	S	ko:K07007	-	ko00000	HI0933-like protein
IPFFCMEA_00150	0.0	opuD	-	-	M	ko:K05020	-	ko00000,ko02000	Belongs to the BCCT transporter (TC 2.A.15) family
IPFFCMEA_00151	2.14e-36	yteV	-	-	S	-	-	-	Sporulation protein Cse60
IPFFCMEA_00153	6.02e-315	yteT	-	-	S	-	-	-	Oxidoreductase family, C-terminal alpha/beta domain
IPFFCMEA_00154	9.64e-94	yteS	-	-	G	-	-	-	transport
IPFFCMEA_00155	8.3e-279	yteR	3.2.1.172	GH105	G	ko:K15532	-	ko00000,ko01000	unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
IPFFCMEA_00156	5.35e-220	lplB13	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IPFFCMEA_00157	1.36e-202	ytdP	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00158	2.13e-75	ytdP	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00159	1.13e-165	ytdP	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00160	0.0	-	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IPFFCMEA_00161	1.19e-190	ytcP	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IPFFCMEA_00162	2.21e-178	ytbQ	1.1.1.203, 1.1.1.388	-	GM	ko:K18981,ko:K19243	ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	NAD dependent epimerase/dehydratase family
IPFFCMEA_00163	2.6e-278	bioI	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IPFFCMEA_00164	2.64e-243	bioB	2.8.1.6	-	H	ko:K01012	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IPFFCMEA_00165	2.68e-159	bioD	6.3.3.3	-	H	ko:K01935	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IPFFCMEA_00166	4.1e-272	bioF	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPFFCMEA_00167	6.14e-235	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IPFFCMEA_00168	6.57e-60	bioA	2.6.1.105, 2.6.1.62	-	H	ko:K00833,ko:K19563	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IPFFCMEA_00169	3.63e-151	bioW	6.2.1.14	-	H	ko:K01906	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IPFFCMEA_00170	4.8e-221	-	-	-	S	-	-	-	Acetyl xylan esterase (AXE1)
IPFFCMEA_00171	4.37e-242	msmR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00172	7.92e-307	msmE	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IPFFCMEA_00173	1.66e-214	amyD	-	-	P	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_00174	7.65e-186	amyC	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IPFFCMEA_00175	0.0	melA	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IPFFCMEA_00176	1.22e-68	ytwF	-	-	P	-	-	-	Sulfurtransferase
IPFFCMEA_00177	0.0	leuS	6.1.1.4	-	J	ko:K01869	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Belongs to the class-I aminoacyl-tRNA synthetase family
IPFFCMEA_00178	3.63e-72	ytvB	-	-	S	-	-	-	Protein of unknown function (DUF4257)
IPFFCMEA_00179	3.82e-183	pfyP	-	-	T	-	-	-	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IPFFCMEA_00180	1.21e-268	yttB	-	-	EGP	-	-	-	Major facilitator superfamily
IPFFCMEA_00181	5.71e-41	yttA	-	-	S	-	-	-	Pfam Transposase IS66
IPFFCMEA_00182	0.0	bceB	-	-	V	ko:K11632,ko:K19080	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter (permease)
IPFFCMEA_00183	3.83e-179	bceA	-	-	V	ko:K02003,ko:K11631,ko:K19079	ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150	ko00000,ko00001,ko00002,ko01504,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_00184	4.53e-239	bceS	2.7.13.3	-	T	ko:K11629,ko:K19077	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	His Kinase A (phosphoacceptor) domain
IPFFCMEA_00185	2.23e-167	graR	-	-	T	ko:K11630,ko:K19078	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01504,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_00186	3.99e-296	ytrF	-	-	V	ko:K02004,ko:K16918	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IPFFCMEA_00187	5.88e-163	ytrE	-	-	V	ko:K16920	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_00188	1.37e-192	-	-	-	-	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	-
IPFFCMEA_00189	4.46e-211	-	-	-	P	ko:K16919	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPFFCMEA_00190	5.96e-207	ytrB	-	-	P	ko:K16921	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_00191	2.68e-87	ytrA	-	-	K	ko:K07979	-	ko00000,ko03000	GntR family transcriptional regulator
IPFFCMEA_00193	1.27e-55	ytzC	-	-	S	-	-	-	Protein of unknown function (DUF2524)
IPFFCMEA_00194	4.06e-245	ytqA	-	-	S	ko:K07139	-	ko00000	Fe-S oxidoreductase
IPFFCMEA_00195	2.75e-136	ytqB	-	-	J	-	-	-	Putative rRNA methylase
IPFFCMEA_00196	2.78e-275	ytpB	4.2.3.130	-	S	ko:K16188	-	ko00000,ko01000	Tetraprenyl-beta-curcumene synthase
IPFFCMEA_00197	2.33e-192	ytpA	3.1.1.5	-	I	ko:K01048	ko00564,map00564	ko00000,ko00001,ko01000	Alpha beta hydrolase
IPFFCMEA_00198	5.88e-88	ytoA	-	-	S	-	-	-	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IPFFCMEA_00199	0.0	ytnA	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_00200	0.0	asnB	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IPFFCMEA_00201	2.26e-286	metK	2.5.1.6	-	H	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IPFFCMEA_00202	0.0	pckA	4.1.1.49	-	C	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IPFFCMEA_00203	5.75e-52	ytmB	-	-	S	-	-	-	Protein of unknown function (DUF2584)
IPFFCMEA_00204	9.48e-191	ytmA	-	-	E	-	-	-	COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IPFFCMEA_00205	7.95e-242	ytlA	-	-	P	ko:K02051	-	ko00000,ko00002,ko02000	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IPFFCMEA_00206	1.5e-184	ytlC	3.6.3.36	-	P	ko:K02049,ko:K10831,ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPFFCMEA_00207	4.43e-182	ytlD	-	-	P	ko:K02050	-	ko00000,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IPFFCMEA_00208	4.47e-113	ytkD	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IPFFCMEA_00209	1.52e-79	ytkC	-	-	S	-	-	-	Bacteriophage holin family
IPFFCMEA_00210	1.8e-99	dps	-	-	P	ko:K04047	-	ko00000,ko03036	Belongs to the Dps family
IPFFCMEA_00212	4.78e-95	ytkA	-	-	S	-	-	-	YtkA-like
IPFFCMEA_00213	8.36e-113	luxS	4.4.1.21	-	T	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	ko00000,ko00001,ko00002,ko01000	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IPFFCMEA_00214	8.96e-134	ytiB	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IPFFCMEA_00215	5.02e-56	rpmE2	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L31
IPFFCMEA_00216	1.03e-315	ythA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IPFFCMEA_00217	1.64e-238	ythB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IPFFCMEA_00218	2.43e-34	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1540)
IPFFCMEA_00219	7.92e-193	mntD	-	-	P	ko:K11709,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
IPFFCMEA_00220	5.85e-293	mntC	-	-	P	ko:K11705,ko:K11708,ko:K19976	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IPFFCMEA_00221	1.5e-179	mntB	3.6.3.35	-	P	ko:K02074,ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IPFFCMEA_00222	3.23e-218	troA	-	-	P	ko:K11707	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IPFFCMEA_00223	1.43e-272	menC	4.2.1.113	-	H	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IPFFCMEA_00224	0.0	menE	6.2.1.26	-	H	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IPFFCMEA_00225	3.45e-200	menB	4.1.3.36	-	H	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IPFFCMEA_00226	9.85e-197	menH	4.2.99.20	-	S	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IPFFCMEA_00227	0.0	menD	2.2.1.9	-	H	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IPFFCMEA_00228	0.0	menF	5.4.4.2	-	HQ	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IPFFCMEA_00229	1.44e-167	yteA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IPFFCMEA_00230	5.69e-195	ytdA	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Nucleotidyl transferase
IPFFCMEA_00231	4.1e-310	ytcA	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPFFCMEA_00232	2.78e-224	ytcB	-	-	M	-	-	-	NAD-dependent epimerase dehydratase
IPFFCMEA_00233	7.32e-292	-	-	-	M	ko:K06338	-	ko00000	Glycosyltransferase Family 4
IPFFCMEA_00235	6.65e-261	cotS	-	-	S	ko:K06337	-	ko00000	Seems to be required for the assembly of the CotSA protein in spores
IPFFCMEA_00236	1.61e-272	cotSA	-	-	M	ko:K06338	-	ko00000	Glycosyl transferases group 1
IPFFCMEA_00237	3.68e-260	cotI	-	-	S	ko:K06331	-	ko00000	Spore coat protein
IPFFCMEA_00238	1.75e-95	ytaB	-	-	T	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	ko00000,ko00001,ko02000	membrane
IPFFCMEA_00239	0.0	glgP	2.4.1.1	GT35	G	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	ko00000,ko00001,ko01000	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IPFFCMEA_00240	0.0	glgA	2.4.1.21	GT5	G	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000,ko01003	Synthesizes alpha-1,4-glucan chains using ADP-glucose
IPFFCMEA_00241	1.58e-239	glgD	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Glucose-1-phosphate adenylyltransferase, GlgD subunit
IPFFCMEA_00242	8.49e-265	glgC	2.7.7.27	-	G	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IPFFCMEA_00243	0.0	glgB	2.4.1.18	CBM48,GH13	G	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IPFFCMEA_00265	5.93e-85	hxlR	-	-	K	-	-	-	transcriptional
IPFFCMEA_00266	5.63e-137	hxlA	4.1.2.43	-	G	ko:K08093	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	3-hexulose-6-phosphate synthase
IPFFCMEA_00267	3.24e-126	hxlB	5.3.1.27	-	G	ko:K08094	ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	SIS domain
IPFFCMEA_00268	9.46e-163	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_00269	3.11e-73	tlpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_00270	7.94e-100	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IPFFCMEA_00271	3.36e-91	nin	-	-	S	-	-	-	Competence protein J (ComJ)
IPFFCMEA_00272	0.0	yckE	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IPFFCMEA_00273	8.9e-22	-	-	-	S	-	-	-	AAA domain
IPFFCMEA_00274	2.13e-113	-	-	-	S	-	-	-	AAA domain
IPFFCMEA_00275	2.49e-27	-	-	-	-	-	-	-	-
IPFFCMEA_00276	1.06e-57	-	-	-	K	-	-	-	MarR family
IPFFCMEA_00277	1.38e-66	yckD	-	-	S	-	-	-	Protein of unknown function (DUF2680)
IPFFCMEA_00278	1.11e-96	yckC	-	-	S	-	-	-	membrane
IPFFCMEA_00281	1.03e-184	yckB	-	-	ET	ko:K02030,ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
IPFFCMEA_00282	3.35e-146	yckA	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPFFCMEA_00283	2.26e-123	yciC	-	-	S	-	-	-	GTPases (G3E family)
IPFFCMEA_00284	2.72e-141	yciC	-	-	S	-	-	-	GTPases (G3E family)
IPFFCMEA_00285	2.12e-87	-	-	-	M	-	-	-	ErfK YbiS YcfS YnhG
IPFFCMEA_00286	2.21e-150	folE2	3.5.4.16	-	S	ko:K09007	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Converts GTP to 7,8-dihydroneopterin triphosphate
IPFFCMEA_00287	5.51e-283	nasA	-	-	P	ko:K02575	ko00910,map00910	ko00000,ko00001,ko00002,ko02000	COG2223 Nitrate nitrite transporter
IPFFCMEA_00288	0.0	nasB	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Assimilatory nitrate reductase (electron transfer subunit)
IPFFCMEA_00289	0.0	nasC	-	-	C	ko:K00372	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPFFCMEA_00290	0.0	nasD	1.7.1.15	-	C	ko:K00362	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IPFFCMEA_00291	1.2e-74	nasE	1.7.1.15	-	P	ko:K00363	ko00910,ko01120,map00910,map01120	ko00000,ko00001,ko00002,ko01000	Nitrite reductase
IPFFCMEA_00292	0.0	nasF	2.1.1.107, 4.2.1.75	-	H	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IPFFCMEA_00293	8.53e-245	ycgT	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	Ferredoxin--NADP reductase
IPFFCMEA_00294	3.3e-200	ycgS	-	-	I	-	-	-	alpha/beta hydrolase fold
IPFFCMEA_00295	3.19e-187	ycgR	-	-	S	ko:K07089	-	ko00000	permeases
IPFFCMEA_00296	3.82e-195	ycgQ	-	-	S	ko:K08986	-	ko00000	membrane
IPFFCMEA_00297	3.92e-288	ycgP	-	-	QT	-	-	-	COG2508 Regulator of polyketide synthase expression
IPFFCMEA_00298	0.0	putP	-	-	E	ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPFFCMEA_00299	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IPFFCMEA_00300	3.63e-218	ycgM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IPFFCMEA_00301	3.69e-185	ycgL	-	-	S	ko:K07074	-	ko00000	Predicted nucleotidyltransferase
IPFFCMEA_00302	1.1e-231	cah	3.1.1.41	-	Q	ko:K01060	ko00311,ko01130,map00311,map01130	ko00000,ko00001,ko01000	Acetyl xylan esterase (AXE1)
IPFFCMEA_00303	5.64e-228	ycgK	-	-	K	ko:K04761	ko02026,map02026	ko00000,ko00001,ko03000	LysR substrate binding domain
IPFFCMEA_00304	1.29e-186	-	-	-	Q	-	-	-	ubiE/COQ5 methyltransferase family
IPFFCMEA_00305	1.05e-136	aroK	2.7.1.71	-	F	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IPFFCMEA_00306	1.31e-140	tmrB	-	-	S	-	-	-	AAA domain
IPFFCMEA_00307	1.83e-191	nadE	6.3.1.5	-	H	ko:K01916	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IPFFCMEA_00308	7.6e-145	ycgI	-	-	S	ko:K09967	-	ko00000	Domain of unknown function (DUF1989)
IPFFCMEA_00309	2.67e-154	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_00310	4.4e-134	ycgH	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_00311	3.07e-194	yqcI	-	-	S	ko:K09190	-	ko00000	YqcI/YcgG family
IPFFCMEA_00312	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IPFFCMEA_00313	2.93e-233	ldh	1.1.1.27	-	C	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	ko00000,ko00001,ko01000,ko04147	Belongs to the LDH MDH superfamily. LDH family
IPFFCMEA_00314	1.31e-121	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IPFFCMEA_00315	0.0	amyE	3.2.1.1	GH13	G	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	ko00000,ko00001,ko01000	alpha-amylase
IPFFCMEA_00316	2.72e-105	ycgB	-	-	-	-	-	-	-
IPFFCMEA_00317	0.0	ycgA	-	-	S	-	-	-	Membrane
IPFFCMEA_00318	4.44e-273	amhX	-	-	S	ko:K14665	-	ko00000,ko01000,ko01002	amidohydrolase
IPFFCMEA_00319	4.73e-209	opuAC	-	-	E	ko:K02001,ko:K02002	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IPFFCMEA_00320	2.1e-186	opuAB	-	-	P	ko:K02001	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	glycine betaine
IPFFCMEA_00321	8.99e-293	opuAA	3.6.3.32	-	E	ko:K02000	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	glycine betaine
IPFFCMEA_00322	4.82e-61	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IPFFCMEA_00323	4.04e-254	-	-	-	EGP	-	-	-	Uncharacterised MFS-type transporter YbfB
IPFFCMEA_00324	2.59e-276	yceI	-	-	P	ko:K08369	-	ko00000,ko02000	Uncharacterised MFS-type transporter YbfB
IPFFCMEA_00325	2.96e-245	yceH	-	-	P	-	-	-	Belongs to the TelA family
IPFFCMEA_00326	0.0	yceG	-	-	S	-	-	-	Putative component of 'biosynthetic module'
IPFFCMEA_00327	1.18e-175	yceF	-	-	P	ko:K05794	-	ko00000	Protein of unknown function (DUF475)
IPFFCMEA_00328	4.97e-138	yceE	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IPFFCMEA_00329	8.9e-137	yceD	-	-	T	ko:K05795	-	ko00000	proteins involved in stress response, homologs of TerZ and
IPFFCMEA_00330	2.53e-139	yceC	3.5.4.33	-	T	ko:K11991	-	ko00000,ko01000,ko03016	proteins involved in stress response, homologs of TerZ and
IPFFCMEA_00331	1.07e-81	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPFFCMEA_00332	6.56e-107	yceB	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPFFCMEA_00333	8.51e-214	penP	3.5.2.6	-	V	ko:K17836,ko:K18766	ko00311,ko01130,ko01501,map00311,map01130,map01501	ko00000,ko00001,ko00002,ko01000,ko01504	beta-lactamase
IPFFCMEA_00334	4.88e-147	lin0465	-	-	S	-	-	-	DJ-1/PfpI family
IPFFCMEA_00335	1.89e-100	yoaW	-	-	-	-	-	-	-
IPFFCMEA_00336	3.7e-201	yoaV	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_00337	1.35e-202	yoaU	-	-	K	-	-	-	LysR substrate binding domain
IPFFCMEA_00338	5.46e-189	yoaT	-	-	S	-	-	-	Protein of unknown function (DUF817)
IPFFCMEA_00339	7e-40	yozG	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00340	3.22e-98	yoaS	-	-	S	-	-	-	Protein of unknown function (DUF2975)
IPFFCMEA_00341	5.78e-215	yoaR	-	-	V	-	-	-	vancomycin resistance protein
IPFFCMEA_00342	2.01e-108	-	-	-	-	-	-	-	-
IPFFCMEA_00345	3.1e-291	oxdD	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IPFFCMEA_00347	1.27e-105	yoqW	-	-	S	-	-	-	Belongs to the SOS response-associated peptidase family
IPFFCMEA_00348	2.87e-119	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IPFFCMEA_00349	1.79e-66	-	4.2.2.10	-	G	ko:K01732	-	ko00000,ko01000	Amb_all
IPFFCMEA_00350	2.09e-144	yoaK	-	-	S	-	-	-	Membrane
IPFFCMEA_00351	3.56e-169	yoaJ	-	-	G	ko:K20628	-	ko00000	Endoglucanase C-terminal domain subunit and related proteins
IPFFCMEA_00352	0.0	yoaI	1.14.14.9	-	Q	ko:K00483	ko00350,ko01120,ko01220,map00350,map01120,map01220	ko00000,ko00001,ko01000	COG2368 Aromatic ring hydroxylase
IPFFCMEA_00353	1.88e-19	yoaH	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	methyl-accepting chemotaxis protein
IPFFCMEA_00354	5.32e-60	-	-	-	L	-	-	-	Transposase and inactivated derivatives, TnpA family
IPFFCMEA_00355	2.2e-100	-	-	-	-	-	-	-	-
IPFFCMEA_00356	5.09e-42	-	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IPFFCMEA_00357	5.92e-194	-	-	-	EG	-	-	-	Spore germination protein
IPFFCMEA_00358	2.28e-13	-	-	-	S	-	-	-	TIGRFAM germination protein, Ger(x)C family
IPFFCMEA_00359	2.56e-34	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IPFFCMEA_00360	7.51e-205	-	-	-	P	-	-	-	Catalase
IPFFCMEA_00362	3.72e-36	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
IPFFCMEA_00363	5.84e-105	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IPFFCMEA_00364	1e-249	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IPFFCMEA_00365	4.34e-75	spoVAE	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IPFFCMEA_00366	1.15e-39	-	-	-	S	-	-	-	Protein of unknown function (DUF1657)
IPFFCMEA_00367	9.73e-194	-	-	-	S	-	-	-	membrane
IPFFCMEA_00368	1.38e-16	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPFFCMEA_00369	1.92e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPFFCMEA_00370	0.0	-	-	-	I	-	-	-	PLD-like domain
IPFFCMEA_00371	7.71e-128	-	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPFFCMEA_00372	2.23e-112	lsrK	2.7.1.189	-	G	ko:K11216	ko02024,map02024	ko00000,ko00001,ko01000	FGGY family of carbohydrate kinases, C-terminal domain
IPFFCMEA_00373	2.24e-300	yoaB	-	-	EGP	-	-	-	the major facilitator superfamily
IPFFCMEA_00374	8.15e-105	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPFFCMEA_00375	7.41e-179	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	AAA domain, putative AbiEii toxin, Type IV TA system
IPFFCMEA_00376	2.92e-120	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IPFFCMEA_00377	6.24e-168	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IPFFCMEA_00378	2.31e-122	yoaA	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPFFCMEA_00379	7.05e-172	yoxB	-	-	-	-	-	-	-
IPFFCMEA_00380	8.07e-53	yoxC	-	-	S	-	-	-	Bacterial protein of unknown function (DUF948)
IPFFCMEA_00381	3.77e-158	fabG	1.1.1.100	-	S	ko:K00059,ko:K07124	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_00382	5.37e-79	rtp	-	-	K	-	-	-	Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IPFFCMEA_00383	1.07e-54	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPFFCMEA_00384	3.43e-100	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPFFCMEA_00385	2.05e-173	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPFFCMEA_00386	2.61e-205	gltC	-	-	K	ko:K09681	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00387	0.0	gltA	1.4.1.13, 1.4.1.14, 1.4.7.1	-	E	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	glutamate synthase
IPFFCMEA_00388	0.0	gltD	1.4.1.13, 1.4.1.14	-	E	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko01000	COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IPFFCMEA_00389	4.18e-237	yogA	-	-	C	ko:K13955	-	ko00000	COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IPFFCMEA_00390	4.34e-201	gltR1	-	-	K	ko:K21959	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00391	0.0	ggt	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IPFFCMEA_00392	3.31e-47	yoeD	-	-	G	-	-	-	Helix-turn-helix domain
IPFFCMEA_00393	1.14e-124	-	-	-	L	-	-	-	Integrase
IPFFCMEA_00395	8.34e-127	yoeB	-	-	S	-	-	-	IseA DL-endopeptidase inhibitor
IPFFCMEA_00396	1.14e-311	yoeA	-	-	V	-	-	-	MATE efflux family protein
IPFFCMEA_00397	1.92e-240	yoxA	5.1.3.3	-	G	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Aldose 1-epimerase
IPFFCMEA_00398	0.0	dacC	3.4.16.4	-	M	ko:K07259	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IPFFCMEA_00399	0.0	-	-	-	Q	ko:K15664,ko:K15666,ko:K15667	ko01054,map01054	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_00400	0.0	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IPFFCMEA_00401	7.8e-49	-	6.3.2.14	-	Q	ko:K02364,ko:K15656,ko:K15668	ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024	ko00000,ko00001,ko01000,ko01008	amino acid activation for nonribosomal peptide biosynthetic process
IPFFCMEA_00402	1.01e-82	yngL	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IPFFCMEA_00403	0.0	yngK	-	-	T	-	-	-	Glycosyl hydrolase-like 10
IPFFCMEA_00404	3.09e-267	yngJ	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IPFFCMEA_00405	0.0	yngI	-	-	IQ	ko:K00666	-	ko00000,ko01000,ko01004	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IPFFCMEA_00406	5.62e-316	yngH	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Biotin carboxylase
IPFFCMEA_00407	7.15e-43	-	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	Biotin carboxyl carrier protein
IPFFCMEA_00408	1.12e-210	yngG	4.1.3.4	-	E	ko:K01640	ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146	ko00000,ko00001,ko00002,ko01000	Hydroxymethylglutaryl-CoA lyase
IPFFCMEA_00409	4.96e-174	yngF	-	-	I	-	-	-	Belongs to the enoyl-CoA hydratase isomerase family
IPFFCMEA_00410	0.0	yngE	-	-	I	-	-	-	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IPFFCMEA_00411	1.74e-294	yngD	-	-	S	ko:K07097	-	ko00000	phosphohydrolase (DHH superfamily)
IPFFCMEA_00412	1.16e-133	yngC	-	-	S	-	-	-	membrane-associated protein
IPFFCMEA_00413	1.07e-207	yngB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IPFFCMEA_00414	1.36e-100	yngA	-	-	S	-	-	-	membrane
IPFFCMEA_00415	8.44e-31	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IPFFCMEA_00416	5.7e-309	xynD	3.2.1.55	CBM6,GH43	G	ko:K15921	ko00520,map00520	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IPFFCMEA_00417	1.89e-31	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
IPFFCMEA_00418	4.5e-242	ynfF	3.2.1.136	GH5	M	ko:K15924	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 30 family
IPFFCMEA_00420	0.0	bglC5	3.2.1.4	GH5,GH9	G	ko:K01179	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	PFAM glycoside hydrolase family 5
IPFFCMEA_00421	0.0	alsT	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IPFFCMEA_00422	8.74e-75	ynfC	-	-	-	-	-	-	-
IPFFCMEA_00423	1.82e-18	-	-	-	-	-	-	-	-
IPFFCMEA_00424	0.0	parC	-	-	L	ko:K02621	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPFFCMEA_00425	0.0	parE	-	-	L	ko:K02622	-	ko00000,ko01000,ko02048,ko03032,ko03036	Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IPFFCMEA_00426	1.72e-90	yneT	-	-	S	ko:K06929	-	ko00000	CoA-binding protein
IPFFCMEA_00427	5.48e-122	plsY	2.3.1.15	-	I	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IPFFCMEA_00428	8.97e-65	yneR	-	-	S	-	-	-	Belongs to the HesB IscA family
IPFFCMEA_00429	3.3e-71	yneQ	-	-	-	-	-	-	-
IPFFCMEA_00430	1.15e-94	yneP	-	-	S	ko:K07107	-	ko00000,ko01000	Thioesterase-like superfamily
IPFFCMEA_00431	6.62e-48	tlp	-	-	S	ko:K06434	-	ko00000	Belongs to the Tlp family
IPFFCMEA_00433	9.26e-10	-	-	-	S	-	-	-	Fur-regulated basic protein B
IPFFCMEA_00434	8.82e-119	yneN	-	-	CO	-	-	-	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPFFCMEA_00435	0.0	citB	4.2.1.3	-	C	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IPFFCMEA_00436	3.75e-21	sspO	-	-	S	ko:K06432	-	ko00000	Belongs to the SspO family
IPFFCMEA_00437	5.65e-27	sspP	-	-	S	ko:K06433	-	ko00000	Belongs to the SspP family
IPFFCMEA_00438	7.02e-86	cotM	-	-	O	ko:K06335	-	ko00000	Spore coat protein
IPFFCMEA_00439	2.79e-97	yneK	-	-	S	-	-	-	Protein of unknown function (DUF2621)
IPFFCMEA_00440	7.34e-66	yqgV	-	-	S	-	-	-	Thiamine-binding protein
IPFFCMEA_00441	2.69e-256	yqgU	-	-	-	-	-	-	-
IPFFCMEA_00442	3.55e-282	yqgT	3.4.19.11	-	E	ko:K01308	-	ko00000,ko01000,ko01002	Gamma-D-glutamyl-L-diamino acid endopeptidase
IPFFCMEA_00443	0.0	yqgS	2.7.8.20	-	M	ko:K01138,ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IPFFCMEA_00444	3.28e-230	glcK	2.7.1.2	-	G	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Glucokinase
IPFFCMEA_00445	9.15e-45	yqgQ	-	-	S	-	-	-	Protein conserved in bacteria
IPFFCMEA_00446	0.0	gluP	3.4.21.105	-	O	ko:K19225	-	ko00000,ko01000,ko01002	membrane protein (homolog of Drosophila rhomboid)
IPFFCMEA_00447	3.38e-14	yqgO	-	-	-	-	-	-	-
IPFFCMEA_00448	4.62e-136	fthC	6.3.3.2	-	H	ko:K01934	ko00670,ko01100,map00670,map01100	ko00000,ko00001,ko01000	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IPFFCMEA_00449	6.25e-29	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IPFFCMEA_00450	1.94e-248	yqgM	2.4.1.250	-	M	ko:K15521	-	ko00000,ko01000	Glycosyl transferases group 1
IPFFCMEA_00452	2.81e-67	yqzD	-	-	-	-	-	-	-
IPFFCMEA_00453	1.09e-93	yqzC	-	-	S	-	-	-	YceG-like family
IPFFCMEA_00454	1.57e-186	pstB	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPFFCMEA_00455	1.14e-188	pstBA	3.6.3.27	-	P	ko:K02036	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IPFFCMEA_00456	5.26e-202	pstA	-	-	P	ko:K02038	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Phosphate transport system permease
IPFFCMEA_00457	7.11e-203	pstC	-	-	P	ko:K02037	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	probably responsible for the translocation of the substrate across the membrane
IPFFCMEA_00458	2.61e-205	pstS	-	-	P	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	ko00000,ko00001,ko00002,ko02000	Phosphate
IPFFCMEA_00459	0.0	pbpA	-	-	M	ko:K21465,ko:K21466	ko00550,map00550	ko00000,ko00001,ko01011	penicillin-binding protein
IPFFCMEA_00460	3.96e-293	yqgE	-	-	EGP	ko:K08222	-	ko00000,ko02000	Major facilitator superfamily
IPFFCMEA_00461	1.59e-148	sodA	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	radicals which are normally produced within the cells and which are toxic to biological systems
IPFFCMEA_00462	2.36e-100	yqgC	-	-	S	ko:K09793	-	ko00000	protein conserved in bacteria
IPFFCMEA_00463	1.12e-167	yqgB	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IPFFCMEA_00464	1.35e-61	yqfZ	-	-	M	ko:K06417	-	ko00000	LysM domain
IPFFCMEA_00465	5.22e-257	ispG	1.17.7.1, 1.17.7.3	-	I	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IPFFCMEA_00466	2.38e-80	yqfX	-	-	S	-	-	-	membrane
IPFFCMEA_00467	8.25e-142	yqfW	-	-	S	ko:K05967	-	ko00000	Belongs to the 5'(3')-deoxyribonucleotidase family
IPFFCMEA_00468	8.59e-107	zur	-	-	P	ko:K02076	-	ko00000,ko03000	Belongs to the Fur family
IPFFCMEA_00469	2.21e-198	yqfU	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPFFCMEA_00470	3.01e-49	yqfT	-	-	S	-	-	-	Protein of unknown function (DUF2624)
IPFFCMEA_00471	1.04e-214	nfo	3.1.21.2	-	L	ko:K01151	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPFFCMEA_00472	1.09e-310	cshB	3.6.4.13	-	JKL	ko:K05592,ko:K18692	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IPFFCMEA_00473	5.01e-47	yqfQ	-	-	S	-	-	-	YqfQ-like protein
IPFFCMEA_00474	1.01e-225	ispH	1.17.7.4	-	IM	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IPFFCMEA_00475	7.29e-267	yqfO	-	-	S	-	-	-	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IPFFCMEA_00476	1.98e-149	trmK	2.1.1.217	-	S	ko:K06967	-	ko00000,ko01000,ko03016	SAM-dependent methyltransferase
IPFFCMEA_00477	1.61e-81	cccA	-	-	C	ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IPFFCMEA_00478	2.29e-253	sigA	-	-	K	ko:K03086	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IPFFCMEA_00479	0.0	dnaG	-	-	L	ko:K02316	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IPFFCMEA_00480	6.03e-114	yqxD	-	-	S	ko:K09768	-	ko00000	Belongs to the UPF0178 family
IPFFCMEA_00481	6.38e-191	yqfL	2.7.11.33, 2.7.4.28	-	S	ko:K09773	-	ko00000,ko01000	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IPFFCMEA_00482	3.29e-144	ccpN	-	-	K	-	-	-	CBS domain
IPFFCMEA_00483	0.0	glyS	6.1.1.14	-	J	ko:K01879	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Glycyl-tRNA synthetase beta subunit
IPFFCMEA_00484	2.12e-222	glyQ	6.1.1.14	-	J	ko:K01878	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	glycyl-tRNA synthetase alpha subunit
IPFFCMEA_00485	2.14e-186	recO	-	-	L	ko:K03584	ko03440,map03440	ko00000,ko00001,ko03400	Involved in DNA repair and RecF pathway recombination
IPFFCMEA_00486	5.29e-27	-	-	-	S	-	-	-	YqzL-like protein
IPFFCMEA_00487	9.98e-215	era	-	-	S	ko:K03595	-	ko00000,ko03009,ko03029	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IPFFCMEA_00488	5.52e-92	cdd	3.5.4.5	-	F	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IPFFCMEA_00489	3.34e-80	dgkA	2.7.1.107, 2.7.1.66	-	M	ko:K00887,ko:K00901	ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231	ko00000,ko00001,ko01000	Diacylglycerol kinase
IPFFCMEA_00490	1.75e-105	ybeY	-	-	S	ko:K07042	-	ko00000,ko03009	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPFFCMEA_00491	0.0	yqfF	-	-	S	ko:K07037	-	ko00000	membrane-associated HD superfamily hydrolase
IPFFCMEA_00493	4.99e-224	phoH	-	-	T	ko:K06217	-	ko00000	Phosphate starvation-inducible protein PhoH
IPFFCMEA_00494	8.52e-242	yqfD	-	-	S	ko:K06438	-	ko00000	Stage IV sporulation
IPFFCMEA_00495	2.07e-60	yqfC	-	-	S	-	-	-	sporulation protein YqfC
IPFFCMEA_00496	2.23e-56	yqfB	-	-	-	-	-	-	-
IPFFCMEA_00497	4.35e-192	yqfA	-	-	S	-	-	-	UPF0365 protein
IPFFCMEA_00498	3.78e-290	yqeZ	-	-	O	ko:K07403	-	ko00000	COG1030 Membrane-bound serine protease (ClpP class)
IPFFCMEA_00499	4.53e-90	yqeY	-	-	S	ko:K09117	-	ko00000	Yqey-like protein
IPFFCMEA_00500	1.03e-26	rpsU	-	-	J	ko:K02970	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bS21 family
IPFFCMEA_00501	4.64e-201	yqeW	-	-	P	ko:K03324	-	ko00000,ko02000	COG1283 Na phosphate symporter
IPFFCMEA_00502	0.0	yqeV	2.8.4.5	-	J	ko:K18707	-	ko00000,ko01000,ko03016	ribosomal protein S12 methylthiotransferase
IPFFCMEA_00503	6.85e-179	rsmE	2.1.1.193	-	J	ko:K09761	-	ko00000,ko01000,ko03009	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IPFFCMEA_00504	2.29e-225	prmA	-	-	J	ko:K02687	-	ko00000,ko01000,ko03009	Methylates ribosomal protein L11
IPFFCMEA_00505	3.41e-257	dnaJ	-	-	O	ko:K03686	-	ko00000,ko03029,ko03110	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IPFFCMEA_00506	0.0	dnaK	-	-	O	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Heat shock 70 kDa protein
IPFFCMEA_00507	4.36e-116	grpE	-	-	O	ko:K03687	-	ko00000,ko03029,ko03110	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPFFCMEA_00508	3.88e-240	hrcA	-	-	K	ko:K03705	-	ko00000,ko03000	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IPFFCMEA_00509	5.86e-276	hemN	-	-	H	-	-	-	Involved in the biosynthesis of porphyrin-containing compound
IPFFCMEA_00510	0.0	lepA	-	-	M	ko:K03596	ko05134,map05134	ko00000,ko00001	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IPFFCMEA_00511	7.06e-70	yqxA	-	-	S	-	-	-	Protein of unknown function (DUF3679)
IPFFCMEA_00512	2.73e-283	spoIIP	-	-	M	ko:K06385	-	ko00000	stage II sporulation protein P
IPFFCMEA_00513	3.42e-258	gpr	3.4.24.78	-	C	ko:K06012	-	ko00000,ko01000,ko01002	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IPFFCMEA_00514	4e-49	rpsT	-	-	J	ko:K02968	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 16S ribosomal RNA
IPFFCMEA_00515	4.06e-244	holA	2.7.7.7	-	L	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III delta subunit
IPFFCMEA_00516	2.36e-22	-	-	-	S	-	-	-	YqzM-like protein
IPFFCMEA_00517	0.0	comEC	-	-	S	ko:K02238	-	ko00000,ko00002,ko02044	Competence protein ComEC
IPFFCMEA_00518	3.25e-137	comEB	3.5.4.12	-	F	ko:K01493	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko02044	ComE operon protein 2
IPFFCMEA_00519	3.69e-135	comEA	-	-	L	ko:K02237	-	ko00000,ko00002,ko02044	COG1555 DNA uptake protein and related DNA-binding proteins
IPFFCMEA_00520	4.46e-188	comER	-	-	E	ko:K02239	-	ko00000,ko00002,ko02044	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPFFCMEA_00521	7.73e-176	yqeM	-	-	Q	-	-	-	Methyltransferase
IPFFCMEA_00522	1.14e-80	rsfS	-	-	J	ko:K09710	-	ko00000,ko03009	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IPFFCMEA_00523	3.95e-132	yqeK	-	-	H	-	-	-	HD superfamily hydrolase involved in NAD metabolism
IPFFCMEA_00524	2.47e-141	nadD	2.7.7.18	-	H	ko:K00969	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IPFFCMEA_00525	8.95e-61	yhbY	-	-	J	ko:K07574	-	ko00000,ko03009	RNA-binding protein containing KH domain, possibly ribosomal protein
IPFFCMEA_00526	8.1e-199	aroE	1.1.1.25	-	E	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IPFFCMEA_00527	4.78e-273	yqeH	-	-	S	ko:K06948	-	ko00000,ko03009	In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IPFFCMEA_00528	2.17e-123	yqeG	-	-	S	ko:K07015	-	ko00000	hydrolase of the HAD superfamily
IPFFCMEA_00530	2.24e-182	yqeF	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPFFCMEA_00531	2.3e-174	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IPFFCMEA_00532	9.36e-135	yqeD	-	-	S	-	-	-	SNARE associated Golgi protein
IPFFCMEA_00533	7.31e-215	yqeC	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconate dehydrogenase
IPFFCMEA_00534	7.4e-168	-	-	-	-	-	-	-	-
IPFFCMEA_00535	2.53e-97	nucB	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IPFFCMEA_00536	7.53e-161	sigK	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_00537	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPFFCMEA_00538	1.14e-197	yybE	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00539	8.28e-87	-	-	-	K	-	-	-	Glyoxalase bleomycin resistance protein dioxygenase
IPFFCMEA_00541	4.93e-266	-	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Aspartate phosphatase response regulator
IPFFCMEA_00542	3.2e-13	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPFFCMEA_00543	1.72e-221	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IPFFCMEA_00544	3.4e-49	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	nucleic acid phosphodiester bond hydrolysis
IPFFCMEA_00546	5.52e-37	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IPFFCMEA_00547	1.1e-20	-	-	-	S	-	-	-	SMI1 / KNR4 family
IPFFCMEA_00548	5.24e-60	-	-	-	-	-	-	-	-
IPFFCMEA_00552	5.5e-37	-	-	-	S	ko:K21492	-	ko00000,ko02048	Suppressor of fused protein (SUFU)
IPFFCMEA_00553	1.89e-40	-	-	-	-	-	-	-	-
IPFFCMEA_00556	6.48e-34	-	-	-	S	-	-	-	Repressor of ComK
IPFFCMEA_00557	8.34e-26	-	-	-	K	ko:K06284	-	ko00000,ko03000	SpoVT / AbrB like domain
IPFFCMEA_00562	4.03e-07	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	DNA segregation ATPase FtsK SpoIIIE and related proteins
IPFFCMEA_00573	1.22e-136	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IPFFCMEA_00575	0.0	-	-	-	D	-	-	-	Phage tail tape measure protein
IPFFCMEA_00578	1.46e-33	-	-	-	-	-	-	-	-
IPFFCMEA_00580	8.3e-40	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IPFFCMEA_00581	8.17e-38	-	-	-	S	-	-	-	Phage head-tail joining protein
IPFFCMEA_00583	5.45e-13	-	-	-	-	-	-	-	-
IPFFCMEA_00584	7.58e-162	-	-	-	S	-	-	-	capsid protein
IPFFCMEA_00585	1.32e-92	-	-	-	S	ko:K06904	-	ko00000	Caudovirus prohead serine protease
IPFFCMEA_00586	1.33e-216	-	-	-	S	-	-	-	portal protein
IPFFCMEA_00588	1.19e-179	terL	-	-	S	-	-	-	Terminase
IPFFCMEA_00589	3.93e-73	-	-	-	L	-	-	-	Terminase, small subunit
IPFFCMEA_00595	2.23e-50	csgA	-	-	S	-	-	-	Sigma-G-dependent sporulation-specific SASP protein
IPFFCMEA_00596	6.92e-41	ybxH	-	-	S	-	-	-	Family of unknown function (DUF5370)
IPFFCMEA_00597	1.24e-191	ybxI	3.5.2.6	-	V	ko:K17838	ko01501,map01501	ko00000,ko00001,ko01000	beta-lactamase
IPFFCMEA_00598	2.99e-311	cypC	1.11.2.4	-	Q	ko:K15629	-	ko00000,ko00199,ko01000	Cytochrome P450
IPFFCMEA_00599	1.28e-37	ybyB	-	-	-	-	-	-	-
IPFFCMEA_00600	0.0	ybeC	-	-	E	-	-	-	amino acid
IPFFCMEA_00601	2.09e-212	glpQ	3.1.3.1, 3.1.4.46	-	C	ko:K01113,ko:K01126	ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	glycerophosphoryl diester phosphodiesterase
IPFFCMEA_00602	0.0	glpT	-	-	G	ko:K02445	-	ko00000,ko02000	-transporter
IPFFCMEA_00603	3.57e-47	-	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IPFFCMEA_00604	8.65e-202	ybfA	-	-	K	-	-	-	FR47-like protein
IPFFCMEA_00605	5.4e-184	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_00606	1.23e-56	ybfB	-	-	G	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_00609	0.0	ybfG	-	-	M	-	-	-	Domain of unknown function (DUF1906)
IPFFCMEA_00611	9.18e-83	ylyA	-	-	T	-	-	-	COG1734 DnaK suppressor protein
IPFFCMEA_00612	3.85e-103	lspA	3.4.23.36	-	MU	ko:K03101	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPFFCMEA_00613	2.38e-223	rluD	5.4.99.23	-	J	ko:K06180	-	ko00000,ko01000,ko03009	Responsible for synthesis of pseudouridine from uracil
IPFFCMEA_00614	4.45e-122	pyrR	2.4.2.9	-	F	ko:K02825	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000,ko03000	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IPFFCMEA_00615	1.3e-294	pyrP	-	-	F	ko:K02824	-	ko00000,ko02000	Xanthine uracil
IPFFCMEA_00616	1.04e-213	pyrB	2.1.3.2	-	F	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the ATCase OTCase family
IPFFCMEA_00617	4.86e-316	pyrC	3.5.2.3	-	F	ko:K01465	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IPFFCMEA_00618	3.76e-269	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IPFFCMEA_00619	0.0	carB	6.3.5.5	-	F	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the CarB family
IPFFCMEA_00620	1.57e-184	pyrK	-	-	C	ko:K02823	ko00240,ko01100,map00240,map01100	ko00000,ko00001	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IPFFCMEA_00621	4.97e-220	pyrD	1.3.1.14	-	F	ko:K17828	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IPFFCMEA_00622	2.67e-163	pyrF	4.1.1.23	-	F	ko:K01591	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IPFFCMEA_00623	3e-147	pyrE	2.4.2.10	-	F	ko:K00762	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPFFCMEA_00624	5.95e-182	cysH	1.8.4.10, 1.8.4.8	-	EH	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the PAPS reductase family. CysH subfamily
IPFFCMEA_00625	2.1e-229	cysP	-	-	P	ko:K16331	-	ko00000,ko02000	phosphate transporter
IPFFCMEA_00626	2.15e-284	sat	2.7.7.4	-	P	ko:K00958	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the sulfate adenylyltransferase family
IPFFCMEA_00627	5.56e-142	cysC	2.7.1.25	-	P	ko:K00860	ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of activated sulfate
IPFFCMEA_00628	6.89e-184	cobA	2.1.1.107	-	H	ko:K02303	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Belongs to the precorrin methyltransferase family
IPFFCMEA_00629	2.06e-187	sirB	4.99.1.4	-	S	ko:K03794	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sirohydrochlorin ferrochelatase
IPFFCMEA_00630	9.28e-108	sirC	1.3.1.76, 4.99.1.4	-	H	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Siroheme synthase
IPFFCMEA_00631	0.0	FbpA	-	-	K	-	-	-	RNA-binding protein homologous to eukaryotic snRNP
IPFFCMEA_00632	0.0	yloB	3.6.3.8	-	P	ko:K01537	-	ko00000,ko01000	COG0474 Cation transport ATPase
IPFFCMEA_00633	8.41e-202	yloC	-	-	S	-	-	-	stress-induced protein
IPFFCMEA_00634	3.97e-54	ylzA	-	-	S	ko:K09777	-	ko00000	Belongs to the UPF0296 family
IPFFCMEA_00635	5.73e-143	gmk	2.7.4.8	-	F	ko:K00942	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko00002,ko01000	Essential for recycling GMP and indirectly, cGMP
IPFFCMEA_00636	6.21e-39	rpoZ	2.7.7.6	-	K	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IPFFCMEA_00637	5.13e-286	coaBC	4.1.1.36, 6.3.2.5	-	H	ko:K01598,ko:K13038	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IPFFCMEA_00638	0.0	priA	-	-	L	ko:K04066	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPFFCMEA_00639	7.97e-108	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPFFCMEA_00640	4.09e-222	fmt	2.1.2.9	-	J	ko:K00604	ko00670,ko00970,map00670,map00970	ko00000,ko00001,ko01000	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPFFCMEA_00641	0.0	sun	2.1.1.176	-	J	ko:K03500	-	ko00000,ko01000,ko03009	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IPFFCMEA_00642	2.07e-261	rlmN	2.1.1.192	-	J	ko:K06941	-	ko00000,ko01000,ko03009	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IPFFCMEA_00643	1.38e-177	stp	3.1.3.16	-	T	ko:K20074	-	ko00000,ko01000,ko01009	phosphatase
IPFFCMEA_00644	0.0	prkC	2.7.11.1	-	KLT	ko:K08884,ko:K12132	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IPFFCMEA_00645	1.37e-215	rsgA	3.1.3.100	-	S	ko:K06949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IPFFCMEA_00646	4.68e-153	rpe	5.1.3.1	-	G	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the ribulose-phosphate 3-epimerase family
IPFFCMEA_00647	8.13e-157	thiN	2.7.6.2	-	H	ko:K00949	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	thiamine pyrophosphokinase
IPFFCMEA_00648	7.06e-36	rpmB	-	-	J	ko:K02902	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL28 family
IPFFCMEA_00649	3.65e-78	yloU	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_00650	0.0	yloV	-	-	S	ko:K07030	-	ko00000	kinase related to dihydroxyacetone kinase
IPFFCMEA_00651	1.45e-153	sdaAB	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IPFFCMEA_00652	1.19e-201	sdaAA	4.3.1.17	-	E	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko01000	L-serine dehydratase
IPFFCMEA_00653	0.0	recG	3.6.4.12	-	L	ko:K03655	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPFFCMEA_00654	6.22e-121	fapR	-	-	K	-	-	-	Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IPFFCMEA_00655	1.68e-229	plsX	2.3.1.15	-	I	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IPFFCMEA_00656	4.39e-217	fabD	2.3.1.39	-	I	ko:K00645,ko:K15327,ko:K15329	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004,ko01008	malonyl CoA-acyl carrier protein transacylase
IPFFCMEA_00657	2.88e-166	fabG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	reductase
IPFFCMEA_00658	1.15e-43	acpP	-	-	IQ	ko:K02078	-	ko00000,ko00001	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPFFCMEA_00659	2.12e-174	rnc	3.1.26.3	-	J	ko:K03685	ko03008,ko05205,map03008,map05205	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IPFFCMEA_00660	0.0	smc	-	-	D	ko:K03529	-	ko00000,ko03036	Required for chromosome condensation and partitioning
IPFFCMEA_00661	3.38e-227	ftsY	-	-	U	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IPFFCMEA_00662	1.67e-114	-	-	-	-	-	-	-	-
IPFFCMEA_00663	5.64e-66	ylxM	-	-	S	ko:K09787	-	ko00000	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IPFFCMEA_00664	1.13e-307	ffh	3.6.5.4	-	U	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko01000,ko02044	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPFFCMEA_00665	1.13e-58	rpsP	-	-	J	ko:K02959	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bS16 family
IPFFCMEA_00666	1.2e-49	ylqC	-	-	S	ko:K06960	-	ko00000	Belongs to the UPF0109 family
IPFFCMEA_00667	3.41e-80	ylqD	-	-	S	-	-	-	YlqD protein
IPFFCMEA_00668	7.5e-122	rimM	-	-	J	ko:K02860	-	ko00000,ko03009	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IPFFCMEA_00669	1.98e-176	trmD	2.1.1.228	-	J	ko:K00554	-	ko00000,ko01000,ko03016	Belongs to the RNA methyltransferase TrmD family
IPFFCMEA_00670	8.14e-75	rplS	-	-	J	ko:K02884	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IPFFCMEA_00671	5.7e-200	rbgA	-	-	S	ko:K14540	-	ko00000,ko03009	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IPFFCMEA_00672	5.83e-175	rnhB	3.1.26.4	-	L	ko:K03470	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPFFCMEA_00673	0.0	ylqG	-	-	-	-	-	-	-
IPFFCMEA_00674	1.7e-59	ylqH	-	-	S	ko:K04061	-	ko00000,ko02044	homolog of the cytoplasmic domain of flagellar protein FhlB
IPFFCMEA_00675	6.77e-269	sucC	6.2.1.5	-	C	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IPFFCMEA_00676	1.53e-213	sucD	6.2.1.5	-	C	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IPFFCMEA_00677	3.48e-213	dprA	-	-	LU	ko:K04096	-	ko00000	Rossmann fold nucleotide-binding protein involved in DNA uptake
IPFFCMEA_00678	0.0	topA	5.99.1.2	-	L	ko:K03168	-	ko00000,ko01000,ko03032,ko03400	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPFFCMEA_00679	2.22e-313	trmFO	2.1.1.74	-	J	ko:K04094	-	ko00000,ko01000,ko03016,ko03036	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IPFFCMEA_00680	6.51e-217	xerC	-	-	L	ko:K03733,ko:K04763	-	ko00000,ko03036	tyrosine recombinase XerC
IPFFCMEA_00681	3.01e-120	hslV	3.4.25.2	-	O	ko:K01419	-	ko00000,ko01000,ko01002	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IPFFCMEA_00682	0.0	hslU	-	-	O	ko:K03667	-	ko00000,ko03110	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IPFFCMEA_00683	1.95e-175	codY	-	-	K	ko:K03706	-	ko00000,ko03000	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IPFFCMEA_00684	9.37e-83	flgB	-	-	N	ko:K02387	ko02040,map02040	ko00000,ko00001,ko02035	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IPFFCMEA_00685	2.16e-98	flgC	-	-	N	ko:K02388	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the flagella basal body rod proteins family
IPFFCMEA_00686	5.5e-53	fliE	-	-	N	ko:K02408	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-basal body
IPFFCMEA_00687	0.0	fliF	-	-	N	ko:K02409	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	The M ring may be actively involved in energy transduction
IPFFCMEA_00688	6.08e-230	fliG	-	-	N	ko:K02410	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IPFFCMEA_00689	4.51e-143	fliH	-	-	NU	ko:K02411	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	COG1317 Flagellar biosynthesis type III secretory pathway protein
IPFFCMEA_00690	3.5e-307	fliI	3.6.3.14	-	NU	ko:K02412	ko02040,map02040	ko00000,ko00001,ko01000,ko02035,ko02044	COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IPFFCMEA_00691	1.79e-91	fliJ	-	-	N	ko:K02413	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar biosynthesis chaperone
IPFFCMEA_00692	1.02e-83	ylxF	-	-	S	-	-	-	MgtE intracellular N domain
IPFFCMEA_00693	1.36e-306	fliK	-	-	N	ko:K02414	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar hook-length control protein
IPFFCMEA_00694	5.67e-96	flgD	-	-	N	ko:K02389	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod modification protein
IPFFCMEA_00695	3.12e-179	flgG	-	-	N	ko:K02390	ko02040,map02040	ko00000,ko00001,ko02035	Flagellar basal body rod
IPFFCMEA_00696	5.59e-78	fliL	-	-	N	ko:K02415	-	ko00000,ko02035	Controls the rotational direction of flagella during chemotaxis
IPFFCMEA_00697	6.61e-231	fliM	-	-	N	ko:K02416	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035	One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IPFFCMEA_00698	1.6e-252	fliY	-	-	N	ko:K02417	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02035,ko02044	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IPFFCMEA_00699	1.22e-76	cheY	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	response regulator
IPFFCMEA_00700	3.99e-130	fliZ	-	-	N	ko:K02418	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthesis protein, FliO
IPFFCMEA_00701	1.21e-141	fliP	-	-	N	ko:K02419	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Plays a role in the flagellum-specific transport system
IPFFCMEA_00702	5.23e-50	fliQ	-	-	N	ko:K02420	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Role in flagellar biosynthesis
IPFFCMEA_00703	1.47e-170	fliR	-	-	N	ko:K02421	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Flagellar biosynthetic protein FliR
IPFFCMEA_00704	3.89e-244	flhB	-	-	N	ko:K02401	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPFFCMEA_00705	0.0	flhA	-	-	N	ko:K02400	ko02040,map02040	ko00000,ko00001,ko02035,ko02044	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IPFFCMEA_00706	8.03e-256	flhF	-	-	N	ko:K02404	-	ko00000,ko02035	Flagellar biosynthesis regulator FlhF
IPFFCMEA_00707	1.81e-199	ylxH	-	-	D	ko:K04562	-	ko00000,ko02035	Belongs to the ParA family
IPFFCMEA_00708	1.49e-251	cheB	3.1.1.61, 3.5.1.44	-	NT	ko:K03412	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IPFFCMEA_00709	0.0	cheA	2.7.13.3	-	NT	ko:K03407	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	COG0643 Chemotaxis protein histidine kinase and related kinases
IPFFCMEA_00710	1.56e-103	cheW	-	-	NT	ko:K03408	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	COG0835 Chemotaxis signal transduction protein
IPFFCMEA_00711	3.42e-142	cheC	-	-	NT	ko:K03410	ko02030,map02030	ko00000,ko00001,ko02035	COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IPFFCMEA_00712	3.34e-112	cheD	3.5.1.44	-	NT	ko:K03411	ko02030,map02030	ko00000,ko00001,ko01000,ko02035	Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IPFFCMEA_00713	6.57e-176	sigD	-	-	K	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	ko00000,ko00001,ko02035,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_00714	6.91e-101	ylxL	-	-	-	-	-	-	-
IPFFCMEA_00715	1.49e-168	rpsB	-	-	J	ko:K02967	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS2 family
IPFFCMEA_00716	9.82e-202	tsf	-	-	J	ko:K02357	-	ko00000,ko03012,ko03029	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPFFCMEA_00717	5.82e-163	pyrH	2.7.4.22	-	F	ko:K09903	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphorylation of UMP to UDP
IPFFCMEA_00718	9.6e-119	frr	-	-	J	ko:K02838	-	ko00000,ko03012	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IPFFCMEA_00719	3.84e-187	uppS	2.5.1.31	-	I	ko:K00806	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPFFCMEA_00720	4.74e-178	cdsA	2.7.7.41	-	S	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	ko00000,ko00001,ko00002,ko01000	Belongs to the CDS family
IPFFCMEA_00721	1.14e-275	dxr	1.1.1.267	-	I	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IPFFCMEA_00722	6.84e-294	rasP	-	-	M	ko:K11749	ko02024,ko04112,map02024,map04112	ko00000,ko00001,ko01000,ko01002	zinc metalloprotease
IPFFCMEA_00723	0.0	proS	6.1.1.15	-	J	ko:K01881	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IPFFCMEA_00724	0.0	polC	2.7.7.7	-	L	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPFFCMEA_00725	1.34e-104	rimP	-	-	S	ko:K09748	-	ko00000,ko03009	Required for maturation of 30S ribosomal subunits
IPFFCMEA_00726	5.49e-261	nusA	-	-	K	ko:K02600	-	ko00000,ko03009,ko03021	Participates in both transcription termination and antitermination
IPFFCMEA_00727	2.01e-57	ylxR	-	-	K	ko:K07742	-	ko00000	nucleic-acid-binding protein implicated in transcription termination
IPFFCMEA_00728	6.16e-63	ylxQ	-	-	J	-	-	-	ribosomal protein
IPFFCMEA_00729	0.0	infB	-	-	J	ko:K02519	-	ko00000,ko03012,ko03029	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPFFCMEA_00730	1.11e-59	ylxP	-	-	S	ko:K09764	-	ko00000	protein conserved in bacteria
IPFFCMEA_00731	3.29e-75	rbfA	-	-	J	ko:K02834	-	ko00000,ko03009	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IPFFCMEA_00732	1.73e-219	truB	5.4.99.25	-	J	ko:K03177,ko:K03483	-	ko00000,ko01000,ko03000,ko03016	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPFFCMEA_00733	2.22e-230	ribF	2.7.1.26, 2.7.7.2	-	H	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the ribF family
IPFFCMEA_00734	7.11e-57	rpsO	-	-	J	ko:K02956	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPFFCMEA_00735	0.0	pnp	2.7.7.8	-	J	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IPFFCMEA_00736	2.4e-231	ylxY	-	-	G	-	-	-	Sporulation protein, polysaccharide deacetylase
IPFFCMEA_00737	1.62e-295	mlpA	-	-	S	-	-	-	Belongs to the peptidase M16 family
IPFFCMEA_00738	1.53e-56	ymxH	-	-	S	-	-	-	YlmC YmxH family
IPFFCMEA_00739	2.16e-207	dpaA	-	-	CH	ko:K06410	-	ko00000	Dipicolinate synthase subunit A
IPFFCMEA_00740	1.36e-139	spoVFB	-	-	H	ko:K06411	-	ko00000	Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IPFFCMEA_00741	4.77e-247	asd	1.2.1.11	-	E	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IPFFCMEA_00742	4.9e-283	dapG	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IPFFCMEA_00743	9.08e-201	dapA	4.3.3.7	-	E	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IPFFCMEA_00744	0.0	rnjB	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPFFCMEA_00745	5.01e-171	tepA	-	-	OU	-	-	-	COG0740 Protease subunit of ATP-dependent Clp proteases
IPFFCMEA_00746	4.94e-44	-	-	-	S	-	-	-	YlzJ-like protein
IPFFCMEA_00747	0.0	ftsK	-	-	D	ko:K03466	-	ko00000,ko03036	Belongs to the FtsK SpoIIIE SftA family
IPFFCMEA_00748	1.28e-171	ymfC	-	-	K	ko:K03710	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00749	5.1e-266	ymfD	-	-	EGP	ko:K08221	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_00750	9.47e-299	albE	-	-	S	-	-	-	Peptidase M16
IPFFCMEA_00751	2.37e-309	ymfH	-	-	S	-	-	-	zinc protease
IPFFCMEA_00752	6.33e-168	ymfI	1.1.1.100	-	S	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IPFFCMEA_00753	5.13e-55	ymfJ	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IPFFCMEA_00754	3.91e-183	ymfK	-	-	S	-	-	-	Protein of unknown function (DUF3388)
IPFFCMEA_00755	3.56e-176	ymfM	-	-	S	ko:K15539	-	ko00000	protein conserved in bacteria
IPFFCMEA_00756	1.36e-131	pgsA	2.7.8.5	-	I	ko:K00995	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPFFCMEA_00757	3.71e-300	cinA	3.5.1.42	-	S	ko:K03742,ko:K03743	ko00760,map00760	ko00000,ko00001,ko01000	Belongs to the CinA family
IPFFCMEA_00758	4.7e-239	recA	-	-	L	ko:K03553	ko03440,map03440	ko00000,ko00001,ko00002,ko03400	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPFFCMEA_00759	1.82e-276	pbpX	-	-	V	-	-	-	Beta-lactamase
IPFFCMEA_00760	4.25e-306	rny	-	-	S	ko:K18682	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	Endoribonuclease that initiates mRNA decay
IPFFCMEA_00761	3.57e-194	ymdB	-	-	S	ko:K02029,ko:K02030,ko:K09769	-	ko00000,ko00002,ko02000	protein conserved in bacteria
IPFFCMEA_00762	2.44e-49	spoVS	-	-	S	ko:K06416	-	ko00000	Stage V sporulation protein S
IPFFCMEA_00763	1.96e-251	tdh	1.1.1.103	-	C	ko:K00060	ko00260,map00260	ko00000,ko00001,ko01000	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IPFFCMEA_00764	1.62e-275	kbl	2.3.1.29, 2.3.1.47	-	H	ko:K00639,ko:K00652	ko00260,ko00780,ko01100,map00260,map00780,map01100	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPFFCMEA_00766	1.12e-07	-	-	-	S	-	-	-	YopX protein
IPFFCMEA_00768	1.76e-59	-	-	-	S	-	-	-	dUTPase
IPFFCMEA_00774	8.23e-215	ygxA	-	-	S	-	-	-	Nucleotidyltransferase-like
IPFFCMEA_00775	5.46e-74	ygzB	-	-	S	-	-	-	UPF0295 protein
IPFFCMEA_00776	2.37e-104	perR	-	-	P	ko:K09825	-	ko00000,ko03000	Belongs to the Fur family
IPFFCMEA_00777	2.92e-113	bcp	1.11.1.15	-	O	ko:K03564	-	ko00000,ko01000	Peroxiredoxin
IPFFCMEA_00778	3.26e-312	gsaB	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IPFFCMEA_00779	8.86e-237	ygaE	-	-	S	-	-	-	Membrane
IPFFCMEA_00780	0.0	ygaD	-	-	V	ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	ABC transporter
IPFFCMEA_00781	8.1e-136	ygaC	-	-	J	ko:K07586	-	ko00000	Belongs to the UPF0374 family
IPFFCMEA_00782	1.88e-63	ygaB	-	-	S	-	-	-	YgaB-like protein
IPFFCMEA_00783	2.35e-14	sspE	-	-	S	ko:K06422	-	ko00000	Small, acid-soluble spore protein, gamma-type
IPFFCMEA_00784	3.13e-172	fabL	1.3.1.104	-	IQ	ko:K10780	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_00785	1.73e-48	yfhS	-	-	-	-	-	-	-
IPFFCMEA_00786	1.99e-266	mutY	-	-	L	ko:K03575	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	A G-specific
IPFFCMEA_00787	2.07e-236	yfhP	-	-	S	ko:K07038	-	ko00000	membrane-bound metal-dependent
IPFFCMEA_00788	0.0	yfhO	-	-	S	-	-	-	Bacterial membrane protein YfhO
IPFFCMEA_00789	3.43e-236	csbB	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPFFCMEA_00790	1.13e-217	yfhM	3.8.1.5	-	S	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Alpha beta hydrolase
IPFFCMEA_00791	6.3e-66	yfhL	-	-	S	-	-	-	SdpI/YhfL protein family
IPFFCMEA_00792	7.22e-119	yfhK	-	-	T	-	-	-	Bacterial SH3 domain homologues
IPFFCMEA_00793	8.95e-60	yfhJ	-	-	S	-	-	-	WVELL protein
IPFFCMEA_00794	2.25e-27	sspK	-	-	S	ko:K06428	-	ko00000	reproduction
IPFFCMEA_00795	2.45e-268	yfhI	-	-	EGP	-	-	-	-transporter
IPFFCMEA_00797	4.58e-69	yfhH	-	-	S	-	-	-	Protein of unknown function (DUF1811)
IPFFCMEA_00798	2.67e-180	recX	-	-	S	ko:K03565	-	ko00000,ko03400	Modulates RecA activity
IPFFCMEA_00799	2.56e-218	yfhF	-	-	S	ko:K07071	-	ko00000	nucleoside-diphosphate sugar epimerase
IPFFCMEA_00801	8.86e-35	yfhD	-	-	S	-	-	-	YfhD-like protein
IPFFCMEA_00802	1.17e-137	yfhC	-	-	C	-	-	-	nitroreductase
IPFFCMEA_00803	9.95e-211	yfhB	-	-	S	-	-	-	PhzF family
IPFFCMEA_00804	5.18e-229	yfhA	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_00805	8.91e-225	yfiZ	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_00806	1.28e-229	yfiY	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IPFFCMEA_00807	0.0	mprF	2.3.2.3	-	S	ko:K14205	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IPFFCMEA_00808	4.26e-103	yfiV	-	-	K	-	-	-	transcriptional
IPFFCMEA_00809	7.8e-22	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IPFFCMEA_00810	1.11e-291	yfiU	-	-	EGP	-	-	-	the major facilitator superfamily
IPFFCMEA_00811	4.67e-127	yfiT	-	-	S	-	-	-	Belongs to the metal hydrolase YfiT family
IPFFCMEA_00812	1.91e-266	yfiS	-	-	EGP	-	-	-	Major facilitator superfamily
IPFFCMEA_00813	4.01e-139	yfiR	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00814	2.68e-252	yfiQ	-	-	G	ko:K21462	-	ko00000	COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IPFFCMEA_00815	7.87e-128	lip	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IPFFCMEA_00816	1.89e-128	padR	-	-	K	-	-	-	transcriptional
IPFFCMEA_00817	3.44e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IPFFCMEA_00818	5.69e-262	-	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	ABC-2 family transporter protein
IPFFCMEA_00819	1.78e-213	drrA	-	-	V	ko:K01990,ko:K09695	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_00820	5.82e-144	yfiK	-	-	KT	ko:K02479	-	ko00000,ko02022	LuxR family transcriptional regulator
IPFFCMEA_00821	1.7e-272	baeS	-	-	T	-	-	-	Histidine kinase
IPFFCMEA_00823	2.97e-208	yfiE	1.13.11.2	-	S	ko:K07104	ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	glyoxalase
IPFFCMEA_00824	1.93e-82	yfiD3	-	-	S	-	-	-	DoxX
IPFFCMEA_00825	0.0	yfiC3	-	-	V	ko:K06147	-	ko00000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPFFCMEA_00826	0.0	yfiB3	-	-	V	ko:K06147	-	ko00000,ko02000	ABC transporter
IPFFCMEA_00827	0.0	glvC	2.7.1.208	-	G	ko:K02749,ko:K02750	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_00828	1.23e-180	-	-	-	K	ko:K03481	-	ko00000,ko03000	Helix-turn-helix domain, rpiR family
IPFFCMEA_00829	0.0	malH	3.2.1.122	GH4	G	ko:K01232	ko00500,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IPFFCMEA_00830	5.59e-61	yfjA	-	-	S	-	-	-	Belongs to the WXG100 family
IPFFCMEA_00831	1.94e-270	yfjB	-	-	-	-	-	-	-
IPFFCMEA_00832	1.02e-184	yfjC	-	-	-	-	-	-	-
IPFFCMEA_00833	1.49e-131	yfjD	-	-	S	-	-	-	Family of unknown function (DUF5381)
IPFFCMEA_00834	1e-105	-	-	-	S	-	-	-	Family of unknown function (DUF5381)
IPFFCMEA_00835	2.9e-74	yfjF	-	-	S	ko:K09771	-	ko00000,ko02000	UPF0060 membrane protein
IPFFCMEA_00836	3.9e-34	sspH	-	-	S	ko:K06425	-	ko00000	Belongs to the SspH family
IPFFCMEA_00837	0.0	acoR	-	-	KQ	ko:K21405	-	ko00000,ko03000	COG3284 Transcriptional activator of acetoin glycerol metabolism
IPFFCMEA_00838	0.0	acoL	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPFFCMEA_00839	4.19e-265	acoC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPFFCMEA_00840	8.81e-241	acoB	-	-	C	ko:K21417	-	ko00000,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPFFCMEA_00841	6.48e-243	acoA	-	-	C	ko:K21416	-	ko00000,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPFFCMEA_00843	7.85e-110	yfjM	-	-	S	-	-	-	Psort location Cytoplasmic, score
IPFFCMEA_00844	1.25e-236	yfjN	-	-	J	-	-	-	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPFFCMEA_00845	3.04e-59	-	-	-	S	-	-	-	YfzA-like protein
IPFFCMEA_00846	0.0	rumA_1	2.1.1.190, 2.1.1.35	-	J	ko:K00557,ko:K03215	-	ko00000,ko01000,ko03009,ko03016	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPFFCMEA_00847	3.92e-214	yfjP	3.2.2.21	-	L	ko:K01247	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IPFFCMEA_00848	1.24e-233	corA	-	-	P	ko:K03284	-	ko00000,ko02000	Mediates influx of magnesium ions
IPFFCMEA_00849	7.99e-193	yfjR	-	-	I	-	-	-	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IPFFCMEA_00850	5.95e-197	pdaA	-	-	G	ko:K01567	-	ko00000,ko01000	deacetylase
IPFFCMEA_00851	3.26e-36	yfjT	-	-	-	-	-	-	-
IPFFCMEA_00852	1.76e-283	yfkA	-	-	S	-	-	-	YfkB-like domain
IPFFCMEA_00853	4.44e-191	yfkC	-	-	M	-	-	-	Mechanosensitive ion channel
IPFFCMEA_00854	3.69e-189	yfkD	-	-	S	-	-	-	YfkD-like protein
IPFFCMEA_00855	5.44e-235	cax	-	-	P	ko:K07300	-	ko00000,ko02000	COG0387 Ca2 H antiporter
IPFFCMEA_00856	1.9e-278	yfkF	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_00857	9.64e-184	yihY	-	-	S	ko:K07058	-	ko00000	Belongs to the UPF0761 family
IPFFCMEA_00858	1.03e-66	yfkI	-	-	S	-	-	-	gas vesicle protein
IPFFCMEA_00859	5.89e-108	yfkJ	3.1.3.48	-	T	ko:K01104	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPFFCMEA_00860	5.99e-41	yfkK	-	-	S	-	-	-	Belongs to the UPF0435 family
IPFFCMEA_00861	6.93e-263	ydiN3	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_00862	1.83e-112	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IPFFCMEA_00863	0.0	yfkN	3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45	-	F	ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IPFFCMEA_00864	6.16e-160	frp	-	-	C	-	-	-	nitroreductase
IPFFCMEA_00865	1.24e-172	treR	-	-	K	ko:K03486	-	ko00000,ko03000	transcriptional
IPFFCMEA_00866	0.0	treC	3.2.1.93	GH13	G	ko:K01226	ko00500,map00500	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPFFCMEA_00867	0.0	treP	2.7.1.201	-	G	ko:K02818,ko:K02819	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_00868	1.43e-41	yfkQ	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IPFFCMEA_00869	1.89e-87	ydhN1	-	-	S	-	-	-	Domain of unknown function (DUF1992)
IPFFCMEA_00870	0.0	yflE	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IPFFCMEA_00871	0.0	nagE	2.7.1.193, 2.7.1.199	-	G	ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IPFFCMEA_00872	1.14e-178	yflG	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IPFFCMEA_00873	1.73e-64	yflH	-	-	S	-	-	-	Protein of unknown function (DUF3243)
IPFFCMEA_00874	6.9e-27	yflI	-	-	-	-	-	-	-
IPFFCMEA_00875	3.16e-25	yflJ	-	-	S	-	-	-	Protein of unknown function (DUF2639)
IPFFCMEA_00876	3.42e-157	yflK	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_00877	2.97e-59	acyP	3.6.1.7	-	C	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	ko00000,ko00001,ko01000	Belongs to the acylphosphatase family
IPFFCMEA_00878	4.6e-274	nos	1.14.14.47	-	C	ko:K00491	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IPFFCMEA_00879	1.7e-192	yflN	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPFFCMEA_00880	5.35e-288	citM	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IPFFCMEA_00881	1.62e-229	yflP	-	-	S	-	-	-	Tripartite tricarboxylate transporter family receptor
IPFFCMEA_00882	2.68e-152	citT	-	-	T	ko:K11638	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	response regulator
IPFFCMEA_00883	0.0	citS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IPFFCMEA_00884	0.0	yflS	-	-	P	ko:K03319	-	ko00000	Sodium:sulfate symporter transmembrane region
IPFFCMEA_00885	1.16e-305	pel	4.2.2.2	-	G	ko:K01728	ko00040,ko02024,map00040,map02024	ko00000,ko00001,ko01000	Pectate lyase
IPFFCMEA_00886	1.71e-76	yflT	-	-	S	-	-	-	Heat induced stress protein YflT
IPFFCMEA_00887	1.06e-31	-	-	-	S	-	-	-	Protein of unknown function (DUF3212)
IPFFCMEA_00888	1.94e-219	yfmC	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IPFFCMEA_00889	8.17e-221	-	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_00890	2.98e-223	fecD	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_00891	1.15e-191	fhuC	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IPFFCMEA_00892	2.84e-240	yfmJ	-	-	S	ko:K07119	-	ko00000	N-terminal domain of oxidoreductase
IPFFCMEA_00894	9.99e-48	ydjO	-	-	S	-	-	-	Cold-inducible protein YdjO
IPFFCMEA_00895	1.46e-201	-	-	-	I	-	-	-	Alpha/beta hydrolase family
IPFFCMEA_00896	6.33e-103	yeaA	-	-	S	-	-	-	Protein of unknown function (DUF4003)
IPFFCMEA_00897	0.0	cotA	1.16.3.3	-	Q	ko:K06324	-	ko00000,ko01000	multicopper oxidases
IPFFCMEA_00898	0.0	gabP	-	-	E	ko:K11735	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_00899	1.76e-198	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPFFCMEA_00900	5.62e-226	yeaC	-	-	S	ko:K03924	-	ko00000,ko01000	COG0714 MoxR-like ATPases
IPFFCMEA_00901	1.07e-283	yeaD	-	-	S	-	-	-	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IPFFCMEA_00902	0.0	yebA	-	-	E	-	-	-	COG1305 Transglutaminase-like enzymes
IPFFCMEA_00903	0.0	guaA	6.3.5.2	-	F	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the synthesis of GMP from XMP
IPFFCMEA_00904	6.3e-111	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_00905	1.15e-314	-	-	-	S	-	-	-	Domain of unknown function (DUF4179)
IPFFCMEA_00906	6.6e-281	pbuG	-	-	S	ko:K06901	-	ko00000,ko02000	permease
IPFFCMEA_00907	5.85e-165	yebC	-	-	M	-	-	-	Membrane
IPFFCMEA_00908	3.07e-142	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPFFCMEA_00909	7.93e-219	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPFFCMEA_00910	1.27e-141	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPFFCMEA_00911	2.46e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IPFFCMEA_00912	3.28e-122	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IPFFCMEA_00913	1.13e-135	opuCD	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPFFCMEA_00914	1.23e-221	opuCC	-	-	M	ko:K05845	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IPFFCMEA_00915	4.63e-144	opuCB	-	-	P	ko:K05846	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1174 ABC-type proline glycine betaine transport systems, permease component
IPFFCMEA_00916	3.23e-269	opuCA	-	-	E	ko:K05847	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IPFFCMEA_00917	8.29e-129	yvbF	-	-	K	ko:K22301	-	ko00000,ko03000	Belongs to the GbsR family
IPFFCMEA_00918	1.32e-133	yvbG	-	-	U	ko:K05595	-	ko00000,ko02000	UPF0056 membrane protein
IPFFCMEA_00919	1.2e-144	yvbH	-	-	S	-	-	-	YvbH-like oligomerisation region
IPFFCMEA_00920	2.66e-155	yvbI	-	-	M	-	-	-	Membrane
IPFFCMEA_00921	0.0	tcaA	-	-	S	ko:K21463	-	ko00000	response to antibiotic
IPFFCMEA_00922	9.77e-106	yvbK	-	-	K	-	-	-	acetyltransferase
IPFFCMEA_00923	1.38e-309	eno	4.2.1.11	-	G	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IPFFCMEA_00924	0.0	gpmI	5.4.2.12	-	G	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of 2-phosphoglycerate and
IPFFCMEA_00925	2.12e-176	tpiA	5.3.1.1	-	G	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IPFFCMEA_00926	1.97e-277	pgk	2.7.2.3	-	F	ko:K00927	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the phosphoglycerate kinase family
IPFFCMEA_00927	5.72e-238	gapA	1.2.1.12	-	G	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IPFFCMEA_00928	4.01e-236	cggR	-	-	K	ko:K05311	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IPFFCMEA_00929	0.0	araE	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPFFCMEA_00930	1.51e-258	araR	-	-	K	ko:K02103	-	ko00000,ko03000	transcriptional
IPFFCMEA_00931	6.01e-245	yvbT	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPFFCMEA_00932	1.99e-205	yvbU	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00933	5.59e-198	yvbV	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_00934	7.07e-307	yvbW	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_00935	2.7e-187	-	-	-	S	-	-	-	Glycosyl hydrolase
IPFFCMEA_00936	6.88e-171	lutC	-	-	S	ko:K00782	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IPFFCMEA_00937	0.0	lutB	-	-	C	ko:K18929	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IPFFCMEA_00938	7.47e-174	lutA	-	-	C	ko:K18928	-	ko00000	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IPFFCMEA_00939	3.88e-57	-	-	-	S	-	-	-	Protein of unknown function (DUF2812)
IPFFCMEA_00940	4.23e-42	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IPFFCMEA_00941	4.36e-136	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_00942	6.28e-251	yvfT	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_00943	8.31e-170	XK27_09830	-	-	V	ko:K01992	-	ko00000,ko00002,ko02000	COG0842 ABC-type multidrug transport system, permease component
IPFFCMEA_00944	1.1e-204	yvfR	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	COG1131 ABC-type multidrug transport system, ATPase component
IPFFCMEA_00945	8.47e-200	rsbQ	-	-	S	ko:K19707	-	ko00000,ko03021	Alpha/beta hydrolase family
IPFFCMEA_00946	1.89e-259	-	3.1.3.3	-	T	ko:K07315	-	ko00000,ko01000,ko03021	response regulator
IPFFCMEA_00947	0.0	ganB	3.2.1.89	-	G	ko:K01224	-	ko00000,ko01000	arabinogalactan
IPFFCMEA_00948	0.0	lacA	3.2.1.23	-	G	ko:K12308	ko00052,map00052	ko00000,ko00001,ko01000	beta-galactosidase
IPFFCMEA_00949	3.82e-194	malG	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IPFFCMEA_00950	5.29e-301	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IPFFCMEA_00951	3.8e-291	cycB	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IPFFCMEA_00952	6.96e-237	lacR	-	-	K	ko:K02529	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_00953	5.87e-147	yvfI	-	-	K	ko:K05799	-	ko00000,ko03000	COG2186 Transcriptional regulators
IPFFCMEA_00954	0.0	lctP	-	-	C	ko:K03303	-	ko00000,ko02000	L-lactate permease
IPFFCMEA_00955	7.32e-143	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IPFFCMEA_00956	4.16e-118	rpoN	-	-	K	ko:K03092	ko02020,ko05111,map02020,map05111	ko00000,ko00001,ko03021	COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IPFFCMEA_00957	5.69e-44	yvfG	-	-	S	-	-	-	YvfG protein
IPFFCMEA_00958	3.07e-240	epsO	-	-	GM	ko:K19431	-	ko00000,ko01000	Exopolysaccharide biosynthesis protein
IPFFCMEA_00959	1.06e-278	epsN	-	-	E	ko:K19430	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IPFFCMEA_00960	3.33e-76	epsM	-	-	GM	ko:K19429	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IPFFCMEA_00961	3.19e-139	epsL	-	-	M	ko:K13012,ko:K19428	-	ko00000,ko01000,ko01005	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IPFFCMEA_00962	0.0	epsK	-	-	S	ko:K19418	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPFFCMEA_00963	5.49e-240	epsJ	-	GT2	S	ko:K19427	-	ko00000,ko01000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPFFCMEA_00964	1.83e-257	epsI	-	-	GM	ko:K19426	-	ko00000,ko01000	pyruvyl transferase
IPFFCMEA_00965	9.61e-246	epsH	-	GT2	S	ko:K19425	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IPFFCMEA_00966	7.25e-264	epsG	-	-	S	ko:K19419	-	ko00000,ko02000	EpsG family
IPFFCMEA_00967	2.06e-277	epsF	-	GT4	M	ko:K19424	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IPFFCMEA_00968	2.16e-202	epsE	-	GT2	M	ko:K19423	-	ko00000,ko01000,ko01003	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPFFCMEA_00969	5.25e-280	epsD	-	GT4	M	ko:K19422	-	ko00000,ko01000	Glycosyl transferase 4-like
IPFFCMEA_00970	0.0	capD	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IPFFCMEA_00971	2.28e-149	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IPFFCMEA_00972	2.78e-158	epsA	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IPFFCMEA_00973	2.07e-97	-	-	-	K	ko:K19417	-	ko00000,ko03000	transcriptional
IPFFCMEA_00974	0.0	pnbA	-	CE10	I	ko:K03929	-	ko00000,ko01000	Belongs to the type-B carboxylesterase lipase family
IPFFCMEA_00976	5.4e-120	padC	-	-	Q	ko:K13727	-	ko00000,ko01000	Phenolic acid decarboxylase
IPFFCMEA_00977	1.18e-60	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
IPFFCMEA_00978	1.27e-22	-	-	-	S	-	-	-	Protein of unknown function (DUF3237)
IPFFCMEA_00979	6.31e-76	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IPFFCMEA_00980	4.86e-23	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IPFFCMEA_00981	1.4e-23	racX	5.1.1.13	-	M	ko:K01779	ko00250,ko01054,map00250,map01054	ko00000,ko00001,ko01000	Belongs to the aspartate glutamate racemases family
IPFFCMEA_00982	2.17e-224	pbpE	-	-	V	-	-	-	Beta-lactamase
IPFFCMEA_00983	3.77e-79	pbpE	-	-	V	-	-	-	Beta-lactamase
IPFFCMEA_00984	0.0	sacB	2.4.1.10, 2.4.1.9	GH68	M	ko:K00692,ko:K20811	ko00500,ko01100,ko02020,map00500,map01100,map02020	ko00000,ko00001,ko01000,ko01003	levansucrase activity
IPFFCMEA_00985	0.0	sacC3	3.2.1.65	GH32	G	ko:K01212	ko00500,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IPFFCMEA_00986	0.0	ybeC	-	-	E	-	-	-	amino acid
IPFFCMEA_00987	4.76e-137	yvdT_1	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_00988	2.57e-67	yvdS	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IPFFCMEA_00989	4.21e-66	yvdR	-	-	P	ko:K11741	-	ko00000,ko02000	Small Multidrug Resistance protein
IPFFCMEA_00990	4.53e-95	yvdQ	-	-	S	-	-	-	Protein of unknown function (DUF3231)
IPFFCMEA_00992	8.17e-135	clpP	3.4.21.92	-	OU	ko:K01358	ko04112,ko04212,map04112,map04212	ko00000,ko00001,ko01000,ko01002	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IPFFCMEA_00993	4.39e-146	pgmB	5.4.2.6	-	S	ko:K01838	ko00500,map00500	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IPFFCMEA_00994	0.0	malL	3.2.1.10	GH13	G	ko:K01182	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPFFCMEA_00995	0.0	yvdK	2.4.1.8	GH65	G	ko:K00691	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Glycoside hydrolase, family 65
IPFFCMEA_00996	1.02e-199	malA	-	-	S	-	-	-	Protein of unknown function (DUF1189)
IPFFCMEA_00997	4.42e-186	malD	-	-	P	ko:K15772	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	transport
IPFFCMEA_00998	2.88e-307	malC	-	-	P	ko:K15771	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1175 ABC-type sugar transport systems, permease components
IPFFCMEA_00999	3.44e-301	mdxE	-	-	G	ko:K02027,ko:K15770,ko:K17237	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2182 Maltose-binding periplasmic proteins domains
IPFFCMEA_01000	0.0	nplT	3.2.1.133, 3.2.1.135, 3.2.1.54	GH13	G	ko:K01208	ko00500,ko01100,map00500,map01100	ko00000,ko00001,ko01000	Alpha amylase, N-terminal ig-like domain
IPFFCMEA_01001	1.54e-221	yvdE	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01002	3.11e-136	yvdD	3.2.2.10	-	S	ko:K06966	ko00230,ko00240,map00230,map00240	ko00000,ko00001,ko01000	Belongs to the LOG family
IPFFCMEA_01003	3.2e-70	yvdC	-	-	S	-	-	-	MazG nucleotide pyrophosphohydrolase domain
IPFFCMEA_01004	0.0	yvdB	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IPFFCMEA_01005	5.3e-137	yvdA	4.2.1.1	-	P	ko:K01673	ko00910,map00910	ko00000,ko00001,ko01000	Reversible hydration of carbon dioxide
IPFFCMEA_01006	5.45e-233	yvcT	1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81	-	CH	ko:K00015,ko:K00090	ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120	ko00000,ko00001,ko01000	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPFFCMEA_01007	0.0	-	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease)
IPFFCMEA_01008	3.67e-180	yxdL_2	-	-	V	ko:K02003,ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_01009	1.68e-252	yvcQ	-	-	T	-	-	-	His Kinase A (phosphoacceptor) domain
IPFFCMEA_01010	3.69e-169	yvcP	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_01011	7.42e-29	-	-	-	-	-	-	-	-
IPFFCMEA_01012	8.35e-185	yvcN	2.3.1.118	-	Q	ko:K00675	-	ko00000,ko01000	Belongs to the arylamine N-acetyltransferase family
IPFFCMEA_01013	3.92e-50	crh	-	-	G	ko:K11184	-	ko00000	Phosphocarrier protein Chr
IPFFCMEA_01014	1.04e-219	whiA	-	-	K	ko:K09762	-	ko00000	May be required for sporulation
IPFFCMEA_01015	5.52e-226	yvcK	-	-	S	-	-	-	Required for morphogenesis under gluconeogenic growth conditions
IPFFCMEA_01016	2.09e-213	yvcJ	-	-	S	ko:K06958	-	ko00000,ko03019	Displays ATPase and GTPase activities
IPFFCMEA_01017	5.65e-116	yvcI	3.6.1.55	-	F	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IPFFCMEA_01018	3.89e-220	trxB	1.8.1.9	-	C	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IPFFCMEA_01019	1.08e-184	spl	-	-	M	ko:K21471	-	ko00000,ko01000,ko01002,ko01011	protein conserved in bacteria
IPFFCMEA_01020	0.0	yvcD	-	-	S	-	-	-	COG0457 FOG TPR repeat
IPFFCMEA_01021	0.0	lmrA	3.6.3.44	-	V	ko:K02021,ko:K18104	ko01501,ko02010,map01501,map02010	ko00000,ko00001,ko00002,ko01000,ko01504,ko02000	ABC transporter
IPFFCMEA_01023	0.0	-	-	-	-	-	-	-	-
IPFFCMEA_01024	3.7e-111	-	-	-	-	-	-	-	-
IPFFCMEA_01025	2.93e-143	hisI	3.5.4.19, 3.6.1.31	-	E	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	belongs to the PRA-CH family
IPFFCMEA_01026	3.97e-176	hisF	-	-	E	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IPFFCMEA_01027	4.61e-167	hisA	5.3.1.16	-	E	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IPFFCMEA_01028	3.29e-146	hisH	-	-	E	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IPFFCMEA_01029	2.02e-138	hisB	4.2.1.19	-	E	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	imidazoleglycerol-phosphate dehydratase
IPFFCMEA_01030	1.81e-292	hisD	1.1.1.23	-	E	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IPFFCMEA_01031	1.06e-147	hisG	2.4.2.17	-	E	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IPFFCMEA_01032	2.42e-281	hisZ	-	-	E	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	ko00000,ko00001,ko00002	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IPFFCMEA_01033	4.31e-179	yvpB	-	-	NU	-	-	-	protein conserved in bacteria
IPFFCMEA_01034	5.68e-156	-	4.2.2.10, 4.2.2.2	-	G	ko:K19551	ko00040,map00040	ko00000,ko00001,ko01000	Pectate lyase
IPFFCMEA_01035	8.8e-241	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IPFFCMEA_01036	0.0	manP	2.7.1.202	-	G	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_01037	0.0	manR	-	-	GKT	ko:K02538,ko:K03491	-	ko00000,ko03000	transcriptional antiterminator
IPFFCMEA_01038	2.43e-58	yjcN	-	-	-	-	-	-	-
IPFFCMEA_01039	3.01e-60	yjcS	-	-	S	-	-	-	Antibiotic biosynthesis monooxygenase
IPFFCMEA_01040	1.08e-60	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_01041	1.12e-33	-	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_01056	5.86e-29	pilT	-	-	NU	ko:K02669	-	ko00000,ko02035,ko02044	PFAM Type II secretion system protein E
IPFFCMEA_01059	8.35e-11	-	-	-	M	-	-	-	NlpC P60 family protein
IPFFCMEA_01069	1.63e-06	-	-	-	S	-	-	-	SEC-C motif
IPFFCMEA_01070	1.38e-56	-	-	-	L	-	-	-	Initiator Replication protein
IPFFCMEA_01071	3.19e-42	-	-	-	-	-	-	-	-
IPFFCMEA_01072	9.42e-201	-	-	-	S	-	-	-	Domain of unknown function (DUF5068)
IPFFCMEA_01073	2.08e-20	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_01074	1e-12	-	-	-	K	ko:K07727	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_01082	1.25e-77	-	-	-	-	-	-	-	-
IPFFCMEA_01088	1.33e-36	-	-	-	-	-	-	-	-
IPFFCMEA_01090	4.75e-07	-	-	-	-	-	-	-	-
IPFFCMEA_01094	1.26e-74	-	-	-	L	ko:K07491	-	ko00000	transposase IS200-family protein
IPFFCMEA_01096	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IPFFCMEA_01097	1.21e-245	namA	1.6.99.1	-	C	ko:K00354	-	ko00000,ko01000	Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IPFFCMEA_01098	3.17e-187	yqjL	-	-	S	-	-	-	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IPFFCMEA_01099	8.59e-27	rpmG	-	-	J	ko:K02913	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL33 family
IPFFCMEA_01100	2.2e-221	rnz	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IPFFCMEA_01101	0.0	zwf	1.1.1.363, 1.1.1.49	-	G	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPFFCMEA_01102	0.0	gnd	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPFFCMEA_01103	1.06e-298	dinB	2.7.7.7	-	L	ko:K02346	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPFFCMEA_01104	4.35e-32	yqzJ	-	-	-	-	-	-	-
IPFFCMEA_01105	1.47e-178	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPFFCMEA_01106	1.57e-177	yqjF	-	-	S	ko:K09166	-	ko00000	Uncharacterized conserved protein (COG2071)
IPFFCMEA_01107	5.26e-259	yqjE	3.4.11.14, 3.4.11.4	-	E	ko:K01258,ko:K01263	-	ko00000,ko01000,ko01002	COG2195 Di- and tripeptidases
IPFFCMEA_01108	0.0	yqjD	2.1.3.15, 6.4.1.3	-	I	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IPFFCMEA_01109	5.45e-94	mce	5.1.99.1	-	E	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0346 Lactoylglutathione lyase and related lyases
IPFFCMEA_01111	9.84e-128	yqjB	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01112	1.73e-221	yqjA	-	-	S	-	-	-	Putative aromatic acid exporter C-terminal domain
IPFFCMEA_01113	1.49e-165	artM	3.6.3.21	-	E	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPFFCMEA_01114	8.94e-143	artQ	-	-	E	ko:K02029	-	ko00000,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPFFCMEA_01115	1.18e-174	artP	-	-	ET	ko:K02030	-	ko00000,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IPFFCMEA_01116	3.79e-101	yqiW	-	-	S	-	-	-	Belongs to the UPF0403 family
IPFFCMEA_01117	4.23e-214	bmrU	-	-	I	-	-	-	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IPFFCMEA_01118	1.79e-266	norA	-	-	EGP	ko:K08153,ko:K19576,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_01119	4.31e-193	-	-	-	K	ko:K19575	-	ko00000,ko00002,ko03000	helix_turn_helix, mercury resistance
IPFFCMEA_01120	3.77e-288	bkdB	2.3.1.12, 2.3.1.168	-	C	ko:K00627,ko:K09699	ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPFFCMEA_01121	6.92e-235	bfmBAB	1.2.4.4	-	C	ko:K00167,ko:K21417	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPFFCMEA_01122	1.11e-237	bfmBAA	1.2.4.4	-	C	ko:K00166	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPFFCMEA_01123	0.0	bfmBC	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPFFCMEA_01124	3.39e-255	buk	2.7.2.7	-	C	ko:K00929	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	Belongs to the acetokinase family
IPFFCMEA_01125	1.92e-262	ldh	1.4.1.9	-	E	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IPFFCMEA_01126	1.18e-196	ptb	2.3.1.19	-	C	ko:K00634	ko00650,ko01100,map00650,map01100	ko00000,ko00001,ko01000	phosphate butyryltransferase
IPFFCMEA_01127	0.0	bkdR	-	-	KT	-	-	-	Transcriptional regulator
IPFFCMEA_01128	1.56e-46	yqzF	-	-	S	-	-	-	Protein of unknown function (DUF2627)
IPFFCMEA_01129	7.23e-208	prpB	4.1.3.30, 5.4.2.9	-	G	ko:K01841,ko:K03417	ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130	ko00000,ko00001,ko01000	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IPFFCMEA_01130	0.0	prpD	4.2.1.79	-	S	ko:K01720	ko00640,map00640	ko00000,ko00001,ko01000	2-methylcitrate dehydratase
IPFFCMEA_01131	3.9e-266	mmgD	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IPFFCMEA_01132	2.01e-267	mmgC	-	-	I	ko:K18244	-	ko00000,ko01000	acyl-CoA dehydrogenase
IPFFCMEA_01133	1.19e-199	mmgB	1.1.1.157	-	I	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	ko00000,ko00001,ko01000	Dehydrogenase
IPFFCMEA_01134	2.59e-277	mmgA	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IPFFCMEA_01135	7.42e-172	yqiK	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IPFFCMEA_01136	5.67e-139	lytC_1	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	Cell wall hydrolase autolysin
IPFFCMEA_01137	4.74e-37	-	-	-	-	-	-	-	-
IPFFCMEA_01138	1.15e-272	yqiG	-	-	C	-	-	-	COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IPFFCMEA_01140	1.89e-186	spo0A	-	-	KT	ko:K07699	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IPFFCMEA_01141	2.54e-303	spoIVB	3.4.21.116	-	M	ko:K06399	-	ko00000,ko01000,ko01002	Stage IV sporulation protein B
IPFFCMEA_01142	0.0	recN	-	-	L	ko:K03631	-	ko00000,ko03400	May be involved in recombinational repair of damaged DNA
IPFFCMEA_01143	3.75e-103	argR	-	-	K	ko:K03402	-	ko00000,ko03000	Regulates arginine biosynthesis genes
IPFFCMEA_01144	2.51e-198	rrmJ	2.1.1.226, 2.1.1.227	-	J	ko:K06442	-	ko00000,ko01000,ko03009	rRNA methylase
IPFFCMEA_01145	0.0	dxs	2.2.1.7	-	H	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IPFFCMEA_01146	4.2e-209	ispA	2.5.1.1, 2.5.1.10, 2.5.1.29	-	H	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IPFFCMEA_01147	1.09e-51	xseB	3.1.11.6	-	L	ko:K03602	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPFFCMEA_01148	1.02e-311	xseA	3.1.11.6	-	L	ko:K03601	ko03430,map03430	ko00000,ko00001,ko01000,ko03400	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IPFFCMEA_01149	1.24e-199	folD	1.5.1.5, 3.5.4.9	-	F	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPFFCMEA_01150	4.8e-86	nusB	-	-	K	ko:K03625	-	ko00000,ko03009,ko03021	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPFFCMEA_01151	9.55e-88	yqhY	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01152	0.0	accC	6.3.4.14, 6.4.1.2	-	I	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IPFFCMEA_01153	3.21e-93	accB	-	-	I	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IPFFCMEA_01154	6.19e-39	ywdA	-	-	-	-	-	-	-
IPFFCMEA_01155	0.0	sacA	3.2.1.26	GH32	G	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	invertase
IPFFCMEA_01156	0.0	sacP	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_01157	8e-178	-	-	-	P	ko:K02598	-	ko00000,ko02000	Formate/nitrite transporter
IPFFCMEA_01158	3.69e-193	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IPFFCMEA_01160	0.0	prtS	3.4.21.110, 3.4.21.96	-	O	ko:K01361,ko:K08652,ko:K14647	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPFFCMEA_01161	2.6e-233	ywcH	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPFFCMEA_01162	1.9e-177	nfrA1	1.5.1.38	-	C	ko:K19285	ko00740,ko01100,map00740,map01100	ko00000,ko00001,ko01000	Oxidoreductase
IPFFCMEA_01163	2.19e-174	rodA	-	-	D	ko:K05837	-	ko00000,ko03036	Belongs to the SEDS family
IPFFCMEA_01165	6.61e-52	ywcE	-	-	S	-	-	-	Required for proper spore morphogenesis. Important for spore germination
IPFFCMEA_01166	1.3e-82	qoxD	1.10.3.12	-	C	ko:K02829	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IPFFCMEA_01167	1.2e-144	qoxC	1.10.3.12	-	C	ko:K02828	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	quinol oxidase, subunit
IPFFCMEA_01168	0.0	qoxB	1.10.3.12	-	C	ko:K02827	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPFFCMEA_01169	6.94e-226	qoxA	1.10.3.12	-	C	ko:K02826	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IPFFCMEA_01170	5.11e-49	ydaS	-	-	S	-	-	-	membrane
IPFFCMEA_01171	0.0	galT	2.7.7.12	-	G	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	ko00000,ko00001,ko00002,ko01000	UDP-glucose--hexose-1-phosphate uridylyltransferase
IPFFCMEA_01172	5.34e-289	galK	2.7.1.6	-	G	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IPFFCMEA_01173	3.33e-77	gtcA	-	-	S	-	-	-	GtrA-like protein
IPFFCMEA_01174	1.98e-157	ywcC	-	-	K	-	-	-	transcriptional regulator
IPFFCMEA_01176	1.23e-63	ywcB	-	-	S	-	-	-	Protein of unknown function, DUF485
IPFFCMEA_01177	0.0	ywcA	-	-	S	ko:K14393	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPFFCMEA_01178	1.47e-143	ywbO	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPFFCMEA_01179	2.54e-307	ywbN	-	-	P	ko:K07223,ko:K16301	-	ko00000,ko01000,ko02000	Dyp-type peroxidase family protein
IPFFCMEA_01180	2.42e-246	ycdO	-	-	P	ko:K07224	-	ko00000,ko02000	periplasmic lipoprotein involved in iron transport
IPFFCMEA_01181	5.68e-314	-	-	-	P	ko:K07243	-	ko00000,ko02000	COG0672 High-affinity Fe2 Pb2 permease
IPFFCMEA_01182	3e-147	thiE	2.5.1.3	-	H	ko:K00788	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IPFFCMEA_01183	5.39e-184	thiM	2.7.1.50	-	H	ko:K00878	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IPFFCMEA_01184	1.28e-201	ywbI	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01185	4.47e-76	ywbH	-	-	S	ko:K06518	-	ko00000,ko02000	Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IPFFCMEA_01186	1.21e-143	ywbG	-	-	M	-	-	-	effector of murein hydrolase
IPFFCMEA_01187	7.14e-276	ywbF	-	-	EGP	ko:K05820	-	ko00000,ko02000	Nucleoside H+ symporter
IPFFCMEA_01188	1.05e-36	ywbE	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2196)
IPFFCMEA_01189	1.28e-276	ywbD	2.1.1.191	-	J	ko:K06969	-	ko00000,ko01000,ko03009	Methyltransferase
IPFFCMEA_01190	8.1e-87	ywbC	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	glyoxalase
IPFFCMEA_01191	2.61e-163	ywbB	-	-	S	-	-	-	Protein of unknown function (DUF2711)
IPFFCMEA_01192	1.81e-311	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPFFCMEA_01193	0.0	epr	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPFFCMEA_01194	4.43e-307	sacX	2.7.1.211	-	G	ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_01195	2.6e-195	sacT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IPFFCMEA_01196	5.37e-216	gspA	-	-	M	-	-	-	General stress
IPFFCMEA_01197	3.49e-158	ywaF	-	-	S	-	-	-	Integral membrane protein
IPFFCMEA_01198	1.25e-114	ywaE	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01199	1.28e-296	tyrS	6.1.1.1	-	J	ko:K01866	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPFFCMEA_01200	0.0	ywaD	3.4.11.10, 3.4.11.6	-	S	ko:K19701	-	ko00000,ko01000,ko01002	PA domain
IPFFCMEA_01201	2.43e-264	mnaA	5.1.3.14	-	M	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	ko00000,ko00001,ko00002,ko01000,ko01005	Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IPFFCMEA_01202	1.64e-204	gtaB	2.7.7.9	-	M	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	UTP-glucose-1-phosphate uridylyltransferase
IPFFCMEA_01203	1.07e-14	-	-	-	L	-	-	-	COG2963 Transposase and inactivated derivatives
IPFFCMEA_01204	2.7e-204	tagH	3.6.3.40	-	GM	ko:K09693	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IPFFCMEA_01205	3.02e-171	tagG	-	-	GM	ko:K09692	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transport permease protein
IPFFCMEA_01207	0.0	tagF2	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IPFFCMEA_01208	0.0	tagF	2.7.8.12	-	M	ko:K09809	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPFFCMEA_01209	2.4e-90	tagD	2.7.7.39	-	IM	ko:K00980	ko00564,map00564	ko00000,ko00001,ko01000	Cytidylyltransferase
IPFFCMEA_01210	4.13e-182	tagA	2.4.1.187	GT26	M	ko:K05946	ko05111,map05111	ko00000,ko00001,ko01000,ko01003	Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IPFFCMEA_01211	1.5e-257	tagB	2.7.8.44	-	M	ko:K21285	-	ko00000,ko01000	glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IPFFCMEA_01212	0.0	lytD	3.2.1.96	-	G	ko:K01227	ko00511,map00511	ko00000,ko00001,ko01000	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPFFCMEA_01213	1.3e-238	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IPFFCMEA_01214	1.05e-250	gerBA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IPFFCMEA_01215	6.06e-61	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IPFFCMEA_01216	7.75e-258	gerBC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IPFFCMEA_01217	8.52e-260	ywtG	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPFFCMEA_01218	3.53e-178	ywtF_2	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01219	1.99e-202	ywtE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IPFFCMEA_01220	3.19e-304	pgdS	-	-	M	-	-	-	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IPFFCMEA_01223	9.18e-172	ydhU	-	-	P	ko:K07217	-	ko00000	Catalase
IPFFCMEA_01224	3.91e-270	ydhT1	3.2.1.78	GH26	G	ko:K01218	ko00051,ko02024,map00051,map02024	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 26 family
IPFFCMEA_01225	1.24e-76	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IPFFCMEA_01226	1.07e-09	manA	5.3.1.8	-	G	ko:K01809	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	mannose-6-phosphate isomerase
IPFFCMEA_01227	3.34e-212	gmuE	2.7.1.4	-	GK	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	COG1940 Transcriptional regulator sugar kinase
IPFFCMEA_01228	2.22e-170	ydhQ	-	-	K	ko:K03492	-	ko00000,ko03000	UTRA
IPFFCMEA_01229	0.0	ydhP	3.2.1.21, 3.2.1.86	GT1	G	ko:K01223,ko:K05350	ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IPFFCMEA_01230	1.2e-114	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPFFCMEA_01231	1.22e-173	celB	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPFFCMEA_01232	2.31e-41	ydhN3	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_01233	2.29e-64	ydhM	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_01234	3.64e-254	ydhL	-	-	EGP	ko:K18567	-	ko00000,ko02000	COG2814 Arabinose efflux permease
IPFFCMEA_01235	5.93e-130	ydhK	-	-	M	-	-	-	Protein of unknown function (DUF1541)
IPFFCMEA_01236	5.22e-229	ydhJ	-	-	S	ko:K06885	-	ko00000	Metal dependent phosphohydrolases with conserved 'HD' motif.
IPFFCMEA_01237	2.78e-110	-	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_01239	5.54e-88	frataxin	-	-	S	ko:K05937	-	ko00000	Domain of unknown function (DU1801)
IPFFCMEA_01240	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IPFFCMEA_01241	4.28e-163	-	-	-	-	-	-	-	-
IPFFCMEA_01242	6.49e-288	ydhE	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IPFFCMEA_01243	5.08e-300	ydhD	-	-	M	-	-	-	Glycosyl hydrolase
IPFFCMEA_01244	1.24e-156	ydhC	-	-	K	-	-	-	FCD
IPFFCMEA_01245	1.77e-155	ydhB	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IPFFCMEA_01246	9.89e-266	tcaB	-	-	EGP	ko:K07552	-	ko00000,ko02000	-transporter
IPFFCMEA_01247	1.9e-89	-	-	-	K	-	-	-	Winged helix DNA-binding domain
IPFFCMEA_01248	6.42e-147	ydgI	-	-	C	-	-	-	nitroreductase
IPFFCMEA_01249	0.0	ydgH	-	-	S	ko:K06994	-	ko00000	drug exporters of the RND superfamily
IPFFCMEA_01250	1.19e-103	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPFFCMEA_01251	6.94e-117	-	-	-	S	-	-	-	DinB family
IPFFCMEA_01252	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_01253	0.0	expZ	-	-	S	ko:K18231	ko02010,map02010	br01600,ko00000,ko00001,ko01504,ko02000	ABC transporter
IPFFCMEA_01254	8.04e-111	yycN	-	-	K	-	-	-	Acetyltransferase
IPFFCMEA_01255	5.76e-70	-	-	-	S	-	-	-	DoxX-like family
IPFFCMEA_01256	2.85e-126	ydgC	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IPFFCMEA_01257	2.19e-56	ydgB	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IPFFCMEA_01258	5.54e-50	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IPFFCMEA_01259	1.28e-98	cotP	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IPFFCMEA_01260	8.96e-160	ydfS	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPFFCMEA_01261	5e-152	ydfR	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPFFCMEA_01263	3.75e-39	-	-	-	-	-	-	-	-
IPFFCMEA_01264	2.4e-21	ydgA	-	-	S	-	-	-	Spore germination protein gerPA/gerPF
IPFFCMEA_01265	2.1e-71	ydfQ	-	-	CO	-	-	-	Thioredoxin
IPFFCMEA_01266	1.28e-61	ydfP	-	-	S	ko:K15977	-	ko00000	DoxX
IPFFCMEA_01267	1.29e-236	ydfO	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IPFFCMEA_01268	7.8e-142	ydfN	-	-	C	ko:K15976	-	ko00000,ko01000	nitroreductase
IPFFCMEA_01269	2.12e-198	ydfM	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPFFCMEA_01270	1.23e-188	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IPFFCMEA_01271	3.77e-149	-	-	-	S	ko:K07150	-	ko00000	Protein of unknown function (DUF554)
IPFFCMEA_01272	4.26e-220	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IPFFCMEA_01275	9.15e-145	yyaC	-	-	S	-	-	-	Sporulation protein YyaC
IPFFCMEA_01276	5.34e-227	yyaD	-	-	S	-	-	-	Membrane
IPFFCMEA_01277	7.41e-45	yyzM	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01278	0.0	yyaE	-	-	C	-	-	-	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IPFFCMEA_01279	5.65e-256	ychF	-	-	J	ko:K06942	-	ko00000,ko03009	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IPFFCMEA_01280	1.01e-61	rpsF	-	-	J	ko:K02990	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Binds together with S18 to 16S ribosomal RNA
IPFFCMEA_01281	1.81e-103	ssb	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IPFFCMEA_01282	4.25e-49	rpsR	-	-	J	ko:K02963	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPFFCMEA_01283	2.07e-187	exoA	3.1.11.2	-	L	ko:K01142	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	exodeoxyribonuclease III
IPFFCMEA_01284	2.65e-60	ccpB	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01285	2.14e-154	ccpB	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01286	4.69e-86	yyaH	4.4.1.5	-	E	ko:K01759	ko00620,map00620	ko00000,ko00001,ko01000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPFFCMEA_01287	3.01e-126	vatD	2.3.1.28, 2.3.1.79	-	S	ko:K00638,ko:K00661,ko:K18234	-	br01600,ko00000,ko01000,ko01504	Bacterial transferase hexapeptide (six repeats)
IPFFCMEA_01288	0.0	-	-	-	EGP	ko:K08369	-	ko00000,ko02000	Major facilitator superfamily
IPFFCMEA_01289	8.54e-215	yyaK	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IPFFCMEA_01290	0.0	yyaL	-	-	O	ko:K06888	-	ko00000	COG1331 Highly conserved protein containing a thioredoxin domain
IPFFCMEA_01291	3.47e-108	-	-	-	L	-	-	-	Bacterial transcription activator, effector binding domain
IPFFCMEA_01292	1.67e-134	yyaP	-	-	H	-	-	-	RibD C-terminal domain
IPFFCMEA_01293	2.25e-15	-	-	-	S	-	-	-	YjbR
IPFFCMEA_01294	2.28e-48	-	-	-	S	-	-	-	YjbR
IPFFCMEA_01295	3.81e-87	-	-	-	K	ko:K19273	-	ko00000,ko01000,ko01504	Acetyltransferase (GNAT) domain
IPFFCMEA_01296	1.55e-125	yyaS	-	-	S	ko:K07149	-	ko00000	Membrane
IPFFCMEA_01297	4.18e-90	yjcF	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_01298	4.54e-100	yybA	-	-	K	-	-	-	transcriptional
IPFFCMEA_01299	4.41e-105	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IPFFCMEA_01300	3.87e-132	yybF	-	-	EGP	ko:K08224	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_01301	6.02e-157	yybG	-	-	S	-	-	-	Pentapeptide repeat-containing protein
IPFFCMEA_01302	5.02e-87	-	-	-	S	-	-	-	SnoaL-like domain
IPFFCMEA_01303	2.05e-183	-	-	-	-	-	-	-	-
IPFFCMEA_01304	7.24e-141	-	-	-	K	-	-	-	TipAS antibiotic-recognition domain
IPFFCMEA_01305	7.94e-200	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_01306	5.21e-70	yybO	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_01308	3.19e-90	-	-	-	-	-	-	-	-
IPFFCMEA_01309	2.83e-209	ppaC	3.6.1.1	-	C	ko:K15986	ko00190,map00190	ko00000,ko00001,ko01000	Inorganic pyrophosphatase
IPFFCMEA_01310	1.3e-87	yybR	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01311	1.71e-67	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IPFFCMEA_01312	6.16e-20	cotF	-	-	M	ko:K06329	-	ko00000	Spore coat protein
IPFFCMEA_01314	4.15e-120	yybS	-	-	S	-	-	-	membrane
IPFFCMEA_01315	1.14e-34	yybS	-	-	S	-	-	-	membrane
IPFFCMEA_01316	0.0	yybT	-	-	T	-	-	-	signaling protein consisting of a modified GGDEF domain and a DHH domain
IPFFCMEA_01317	2.74e-96	rplI	-	-	J	ko:K02939	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IPFFCMEA_01318	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPFFCMEA_01319	1.15e-280	yycB	-	-	P	ko:K03449	-	ko00000,ko02000	COG2807 Cyanate permease
IPFFCMEA_01320	1.89e-22	yycC	-	-	K	-	-	-	YycC-like protein
IPFFCMEA_01322	2.87e-39	yycD	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IPFFCMEA_01323	0.0	dnaB	3.6.4.12	-	L	ko:K02314	ko03030,ko04112,map03030,map04112	ko00000,ko00001,ko01000,ko03032	Participates in initiation and elongation during chromosome replication
IPFFCMEA_01324	3.17e-97	yycE	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPFFCMEA_01325	3.02e-313	purA	6.3.4.4	-	F	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IPFFCMEA_01330	2.07e-172	yycF	-	-	T	ko:K07668	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_01331	0.0	vicK	2.7.13.3	-	T	ko:K07652	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_01332	0.0	yycH	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01333	3.44e-200	yycI	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01334	1.15e-190	vicX	3.1.26.11	-	S	ko:K00784	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IPFFCMEA_01335	2.32e-279	yyxA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPFFCMEA_01336	0.0	rocR	-	-	KT	ko:K06714	-	ko00000,ko03000	COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IPFFCMEA_01337	2.31e-54	sdpR	-	-	K	-	-	-	transcriptional
IPFFCMEA_01338	3.95e-87	yvaZ	-	-	S	-	-	-	Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
IPFFCMEA_01339	6.81e-19	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IPFFCMEA_01340	4.85e-119	-	-	-	-	-	-	-	-
IPFFCMEA_01341	5.82e-20	-	-	-	-	-	-	-	-
IPFFCMEA_01342	1.01e-294	rocD	2.6.1.13	-	E	ko:K00819	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000,ko01007	Catalyzes the interconversion of ornithine to glutamate semialdehyde
IPFFCMEA_01343	0.0	rocE	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPFFCMEA_01344	3.22e-213	rocF	3.5.3.1	-	E	ko:K01476	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IPFFCMEA_01346	2.06e-204	-	-	-	S	-	-	-	aspartate phosphatase
IPFFCMEA_01347	1.17e-18	-	-	-	S	-	-	-	aspartate phosphatase
IPFFCMEA_01348	4.15e-108	yycN	-	-	K	-	-	-	Acetyltransferase
IPFFCMEA_01349	1.02e-86	yycO	-	-	S	-	-	-	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IPFFCMEA_01350	1.37e-22	yycP	-	-	-	-	-	-	-
IPFFCMEA_01351	2.65e-207	yycP	-	-	-	-	-	-	-
IPFFCMEA_01352	4.53e-41	yycQ	-	-	S	-	-	-	Protein of unknown function (DUF2651)
IPFFCMEA_01354	2.12e-296	yycR	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IPFFCMEA_01355	1.64e-89	-	-	-	-	-	-	-	-
IPFFCMEA_01357	5e-106	rlmH	2.1.1.177	-	J	ko:K00783	-	ko00000,ko01000,ko03009	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IPFFCMEA_01359	3.91e-135	-	-	-	L	-	-	-	helicase superfamily c-terminal domain
IPFFCMEA_01360	8.76e-104	fri	-	-	P	ko:K04047	-	ko00000,ko03036	Ferritin-like domain
IPFFCMEA_01361	2.71e-176	yusZ	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_01362	5.75e-160	-	2.3.1.29	-	H	ko:K00639	ko00260,map00260	ko00000,ko00001,ko01000,ko01007	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IPFFCMEA_01363	1.26e-18	-	-	-	-	-	-	-	-
IPFFCMEA_01365	3.05e-20	-	-	-	S	-	-	-	Evidence 4 Homologs of previously reported genes of
IPFFCMEA_01367	2.94e-17	-	-	-	EGP	-	-	-	Major Facilitator
IPFFCMEA_01368	6.4e-09	-	-	-	J	-	-	-	O-methyltransferase
IPFFCMEA_01369	3.54e-95	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC superfamily ATP binding cassette transporter ABC protein
IPFFCMEA_01370	2.98e-14	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IPFFCMEA_01372	0.0	pepF2	-	-	E	-	-	-	COG1164 Oligoendopeptidase F
IPFFCMEA_01373	3.48e-88	-	-	-	S	-	-	-	YusW-like protein
IPFFCMEA_01374	8.74e-196	yusV	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPFFCMEA_01375	3.99e-53	yusU	-	-	S	-	-	-	Protein of unknown function (DUF2573)
IPFFCMEA_01376	5.68e-202	gltR	-	-	K	ko:K21959	-	ko00000,ko03000	LysR substrate binding domain
IPFFCMEA_01377	4.97e-138	yusR	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_01378	4.86e-84	yusQ	-	-	S	-	-	-	Tautomerase enzyme
IPFFCMEA_01379	0.0	yusP	-	-	P	-	-	-	Major facilitator superfamily
IPFFCMEA_01380	6.35e-98	yusO	-	-	K	-	-	-	Iron dependent repressor, N-terminal DNA binding domain
IPFFCMEA_01381	8.66e-70	yusN	-	-	M	-	-	-	Coat F domain
IPFFCMEA_01382	2.23e-54	-	-	-	-	-	-	-	-
IPFFCMEA_01383	8.15e-210	fadM	-	-	E	ko:K00318	ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130	ko00000,ko00001,ko01000	Proline dehydrogenase
IPFFCMEA_01384	1.11e-13	-	-	-	S	-	-	-	YuzL-like protein
IPFFCMEA_01385	0.0	fadN	1.1.1.35	-	I	ko:K07516	ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212	ko00000,ko00001,ko00002,ko01000	3-hydroxyacyl-CoA dehydrogenase
IPFFCMEA_01386	3.15e-277	fadA	2.3.1.16	-	I	ko:K00632	ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212	ko00000,ko00001,ko00002,ko01000	Belongs to the thiolase family
IPFFCMEA_01387	0.0	fadE	1.3.8.1	-	I	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	ko00000,ko00001,ko01000	acyl-CoA dehydrogenase
IPFFCMEA_01388	1.01e-83	yusI	1.20.4.1	-	P	ko:K00537	-	ko00000,ko01000	Belongs to the ArsC family
IPFFCMEA_01389	5.91e-85	gcvH	-	-	E	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002	Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IPFFCMEA_01390	2.11e-53	yusG	-	-	S	-	-	-	Protein of unknown function (DUF2553)
IPFFCMEA_01391	8.9e-96	yusF	-	-	L	ko:K07476	-	ko00000	COG1658 Small primase-like proteins (Toprim domain)
IPFFCMEA_01392	8.14e-73	yusE	-	-	CO	-	-	-	Thioredoxin
IPFFCMEA_01393	1.53e-74	yusD	-	-	S	-	-	-	SCP-2 sterol transfer family
IPFFCMEA_01394	2.15e-236	metN	-	-	P	ko:K02071	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IPFFCMEA_01395	6.5e-126	metI	-	-	P	ko:K02069,ko:K02072	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG2011 ABC-type metal ion transport system, permease component
IPFFCMEA_01396	1.96e-187	metQ	-	-	P	ko:K02072,ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the NlpA lipoprotein family
IPFFCMEA_01397	1.56e-80	yurZ	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPFFCMEA_01398	4.46e-182	sufC	-	-	O	ko:K09013	-	ko00000,ko02000	COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IPFFCMEA_01399	6.1e-312	sufD	-	-	O	ko:K07033,ko:K09015	-	ko00000	assembly protein SufD
IPFFCMEA_01400	2.81e-299	sufS	2.8.1.7, 4.4.1.16	-	E	ko:K11717	ko00450,ko01100,map00450,map01100	ko00000,ko00001,ko01000	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPFFCMEA_01401	6.26e-101	nifU	-	-	C	ko:K04488	-	ko00000	COG0822 NifU homolog involved in Fe-S cluster formation
IPFFCMEA_01402	0.0	sufB	-	-	O	ko:K07033,ko:K09014	-	ko00000	FeS cluster assembly
IPFFCMEA_01403	1.79e-149	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPFFCMEA_01407	7.24e-60	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_01408	1.7e-08	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_01409	4.59e-23	-	-	-	-	-	-	-	-
IPFFCMEA_01411	2.79e-87	-	-	-	L	-	-	-	dnaD_dom DnaD domain protein
IPFFCMEA_01412	2.01e-64	-	-	-	L	ko:K02315,ko:K11144	-	ko00000,ko03032	DNA replication protein
IPFFCMEA_01414	1.88e-09	-	-	-	-	-	-	-	-
IPFFCMEA_01415	1.54e-217	cysK	2.5.1.47	-	E	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the cysteine synthase cystathionine beta- synthase family
IPFFCMEA_01416	2.41e-204	yacD	5.2.1.8	-	O	ko:K07533	-	ko00000,ko01000,ko03110	peptidyl-prolyl isomerase
IPFFCMEA_01417	9.54e-208	hslO	-	-	O	ko:K04083	-	ko00000,ko03110	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IPFFCMEA_01418	6.92e-189	coaX	2.7.1.33	-	F	ko:K03525	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IPFFCMEA_01419	0.0	ftsH	-	-	O	ko:K03798	-	ko00000,ko00002,ko01000,ko01002,ko03110	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPFFCMEA_01420	4.82e-121	hpt	2.4.2.8, 6.3.4.19	-	F	ko:K00760,ko:K15780	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Belongs to the purine pyrimidine phosphoribosyltransferase family
IPFFCMEA_01421	0.0	tilS	2.4.2.8, 6.3.4.19	-	D	ko:K04075,ko:K15780	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000,ko03016	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IPFFCMEA_01422	6.63e-234	yabT	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	serine threonine protein kinase
IPFFCMEA_01423	5.61e-168	yabS	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IPFFCMEA_01424	0.0	spoIIE	3.1.3.16	-	KT	ko:K06382	-	ko00000,ko01000	stage II sporulation protein E
IPFFCMEA_01427	2.49e-82	yabR	-	-	J	ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IPFFCMEA_01428	4.18e-75	divIC	-	-	D	ko:K13052	-	ko00000,ko03036	Septum formation initiator
IPFFCMEA_01429	2.58e-138	yabQ	-	-	S	-	-	-	spore cortex biosynthesis protein
IPFFCMEA_01430	1.91e-66	yabP	-	-	S	-	-	-	Sporulation protein YabP
IPFFCMEA_01431	4.22e-50	yabO	-	-	J	-	-	-	COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IPFFCMEA_01432	0.0	yabN	3.6.1.66	-	S	ko:K02428,ko:K02499	ko00230,map00230	ko00000,ko00001,ko01000,ko03036	COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IPFFCMEA_01433	0.0	yabM	-	-	S	ko:K03328	-	ko00000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPFFCMEA_01434	5.88e-121	spoVT	-	-	K	ko:K04769	-	ko00000,ko03000	stage V sporulation protein
IPFFCMEA_01435	0.0	mfd	-	-	L	ko:K03723	ko03420,map03420	ko00000,ko00001,ko01000,ko03400	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IPFFCMEA_01436	6.36e-54	yabK	-	-	S	-	-	-	Peptide ABC transporter permease
IPFFCMEA_01437	2.03e-135	pth	3.1.1.29	-	J	ko:K01056	-	ko00000,ko01000,ko03012	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IPFFCMEA_01438	1.69e-135	ctc	-	-	J	ko:K02897	ko03010,map03010	ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPFFCMEA_01439	7.08e-223	prs	2.7.6.1	-	F	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPFFCMEA_01440	1.49e-308	glmU	2.3.1.157, 2.7.7.23	-	M	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IPFFCMEA_01441	2.45e-63	spoVG	-	-	D	ko:K06412	-	ko00000	Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IPFFCMEA_01442	3.45e-83	yabJ	3.5.99.10	-	J	ko:K09022	-	ko00000,ko01000	translation initiation inhibitor, yjgF family
IPFFCMEA_01443	3.82e-195	purR	-	-	F	ko:K09685	-	ko00000,ko03000	pur operon repressor
IPFFCMEA_01444	9.53e-207	ispE	2.7.1.148	-	I	ko:K00919,ko:K16924	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko02000	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPFFCMEA_01445	3.96e-37	sspF	-	-	S	ko:K06423	-	ko00000	DNA topological change
IPFFCMEA_01446	5.32e-53	veg	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01447	1.11e-198	yabG	-	-	S	ko:K06436	-	ko00000	peptidase
IPFFCMEA_01448	1.24e-199	ksgA	2.1.1.182	-	J	ko:K02528	-	ko00000,ko01000,ko03009	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IPFFCMEA_01449	2.46e-126	rnmV	3.1.26.8	-	J	ko:K05985	-	ko00000,ko01000	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IPFFCMEA_01450	1.18e-277	yabE	-	-	T	-	-	-	protein conserved in bacteria
IPFFCMEA_01451	5.9e-184	tatD	-	-	L	ko:K03424	-	ko00000,ko01000	hydrolase, TatD
IPFFCMEA_01452	0.0	metG	6.1.1.10	-	J	ko:K01874	ko00450,ko00970,map00450,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPFFCMEA_01453	1.51e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	COG2002 Regulators of stationary sporulation gene expression
IPFFCMEA_01454	2.95e-207	rsmI	2.1.1.198	-	H	ko:K07056	-	ko00000,ko01000,ko03009	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IPFFCMEA_01455	2.84e-63	yazA	-	-	L	ko:K07461	-	ko00000	endonuclease containing a URI domain
IPFFCMEA_01456	4.66e-177	yabB	2.1.1.223	-	S	ko:K07461,ko:K15460	-	ko00000,ko01000,ko03016	Conserved hypothetical protein 95
IPFFCMEA_01457	1.53e-56	yabA	-	-	L	-	-	-	Involved in initiation control of chromosome replication
IPFFCMEA_01458	6.33e-189	yaaT	-	-	S	-	-	-	stage 0 sporulation protein
IPFFCMEA_01459	2.82e-235	holB	2.7.7.7	-	L	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III
IPFFCMEA_01460	1.26e-95	yaaR	-	-	S	ko:K09770	-	ko00000	protein conserved in bacteria
IPFFCMEA_01461	1.02e-72	yaaQ	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01462	4.67e-146	tmk	2.7.4.9	-	F	ko:K00943	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPFFCMEA_01463	0.0	yaaO	-	-	E	-	-	-	Orn Lys Arg decarboxylase
IPFFCMEA_01464	1.19e-258	yaaN	-	-	P	-	-	-	Belongs to the TelA family
IPFFCMEA_01465	6.08e-129	xpaC	-	-	S	-	-	-	5-bromo-4-chloroindolyl phosphate hydrolysis protein
IPFFCMEA_01466	2.21e-42	csfB	-	-	S	-	-	-	Inhibitor of sigma-G Gin
IPFFCMEA_01467	2.52e-122	thiT	-	-	S	ko:K16789	-	ko00000,ko02000	Thiamine transporter protein (Thia_YuaJ)
IPFFCMEA_01468	5.71e-121	-	-	-	M	-	-	-	FR47-like protein
IPFFCMEA_01469	9.14e-258	yuaG	-	-	S	ko:K07192	ko04910,map04910	ko00000,ko00001,ko03036,ko04131,ko04147	protein conserved in bacteria
IPFFCMEA_01470	1.68e-109	yuaF	-	-	OU	-	-	-	Membrane protein implicated in regulation of membrane protease activity
IPFFCMEA_01471	6.53e-108	yuaE	-	-	S	-	-	-	DinB superfamily
IPFFCMEA_01472	1.92e-275	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IPFFCMEA_01473	1.19e-135	-	-	-	S	-	-	-	Phage tail protein
IPFFCMEA_01474	0.0	-	-	-	D	-	-	-	phage tail tape measure protein
IPFFCMEA_01476	1.77e-05	-	-	-	-	-	-	-	-
IPFFCMEA_01477	1.67e-101	-	-	-	N	-	-	-	Phage major tail protein phi13
IPFFCMEA_01479	8.4e-67	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IPFFCMEA_01480	5.23e-52	-	-	-	S	-	-	-	Phage head-tail joining protein
IPFFCMEA_01481	1.4e-50	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IPFFCMEA_01482	1.89e-34	-	-	-	-	-	-	-	-
IPFFCMEA_01483	1.06e-266	-	-	-	S	-	-	-	capsid protein
IPFFCMEA_01484	6.14e-151	-	-	-	OU	-	-	-	Belongs to the peptidase S14 family
IPFFCMEA_01485	2.64e-303	-	-	-	S	-	-	-	Phage portal protein
IPFFCMEA_01487	0.0	-	-	-	S	-	-	-	Terminase
IPFFCMEA_01488	5.19e-102	-	-	-	L	-	-	-	phage terminase small subunit
IPFFCMEA_01489	1.19e-66	-	-	-	V	ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IPFFCMEA_01491	7.11e-39	-	-	-	-	-	-	-	-
IPFFCMEA_01492	1.84e-105	-	-	-	L	-	-	-	Transposase
IPFFCMEA_01494	6e-147	-	-	-	-	-	-	-	-
IPFFCMEA_01495	1.19e-37	-	-	-	-	-	-	-	-
IPFFCMEA_01498	1.78e-34	yqaO	-	-	S	-	-	-	Phage-like element PBSX protein XtrA
IPFFCMEA_01499	2.02e-81	rusA	-	-	L	-	-	-	Endodeoxyribonuclease RusA
IPFFCMEA_01501	6.06e-102	yqaM	-	-	L	-	-	-	IstB-like ATP binding protein
IPFFCMEA_01502	4.69e-96	yqaL	-	-	L	-	-	-	DnaD domain protein
IPFFCMEA_01504	1.8e-87	pi112	-	-	L	-	-	-	PDDEXK-like domain of unknown function (DUF3799)
IPFFCMEA_01505	8.41e-125	-	-	-	-	-	-	-	-
IPFFCMEA_01510	3.14e-110	-	-	-	-	-	-	-	-
IPFFCMEA_01511	1.22e-48	-	-	-	S	-	-	-	DNA binding
IPFFCMEA_01512	1.68e-48	-	-	-	-	-	-	-	-
IPFFCMEA_01513	1.5e-26	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_01514	6.71e-28	-	-	-	K	-	-	-	transcriptional
IPFFCMEA_01515	2.71e-61	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IPFFCMEA_01516	1.91e-182	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPFFCMEA_01517	0.0	groL	-	-	O	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IPFFCMEA_01518	2.14e-58	groS	-	-	O	ko:K04078	-	ko00000,ko03029,ko03110	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPFFCMEA_01519	3e-167	ydiL	-	-	S	ko:K07052	-	ko00000	CAAX protease self-immunity
IPFFCMEA_01520	3.2e-37	ydiK	-	-	S	-	-	-	Domain of unknown function (DUF4305)
IPFFCMEA_01521	3.55e-161	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPFFCMEA_01522	5.48e-31	tatA	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IPFFCMEA_01523	2.14e-148	rex	-	-	K	ko:K01926	-	ko00000,ko03000	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IPFFCMEA_01524	1.46e-117	moaC	4.6.1.17	-	H	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IPFFCMEA_01525	0.0	ydiF	-	-	S	ko:K06158	-	ko00000,ko03012	ABC transporter
IPFFCMEA_01526	1.34e-240	tsaD	2.3.1.234	-	O	ko:K01409	-	ko00000,ko01000,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPFFCMEA_01527	2e-108	rimI	2.3.1.128	-	K	ko:K03789	-	ko00000,ko01000,ko03009	This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IPFFCMEA_01528	2.8e-160	yeaZ	2.3.1.234	-	O	ko:K01409,ko:K14742	-	ko00000,ko01000,ko03016	COG1214 Inactive homolog of metal-dependent proteases
IPFFCMEA_01529	3.68e-112	ydiB	-	-	S	ko:K06925	-	ko00000,ko03016	ATPase or kinase
IPFFCMEA_01530	1.75e-227	thiL	2.7.4.16	-	H	ko:K00946	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IPFFCMEA_01535	9.03e-142	-	-	-	V	ko:K06877,ko:K07451	-	ko00000,ko01000,ko02048	HNH endonuclease
IPFFCMEA_01538	7.26e-146	-	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPFFCMEA_01539	1.24e-21	-	-	-	-	-	-	-	-
IPFFCMEA_01545	4.64e-10	-	-	-	-	-	-	-	-
IPFFCMEA_01546	1.25e-13	-	-	-	S	-	-	-	YvrJ protein family
IPFFCMEA_01547	1.09e-64	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	COG1191 DNA-directed RNA polymerase specialized sigma subunit
IPFFCMEA_01548	1.96e-17	-	-	-	-	-	-	-	-
IPFFCMEA_01550	1.92e-19	-	-	-	V	-	-	-	VanZ like family
IPFFCMEA_01551	6.11e-23	-	-	-	S	ko:K07171	-	ko00000,ko01000,ko02048	PemK-like, MazF-like toxin of type II toxin-antitoxin system
IPFFCMEA_01558	2.14e-109	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_01564	3.15e-59	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IPFFCMEA_01567	1.19e-98	-	-	-	S	ko:K02004	-	ko00000,ko00002,ko02000	bacteriocin-associated integral membrane protein
IPFFCMEA_01568	5.23e-85	-	-	-	V	ko:K02003,ko:K09810	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPFFCMEA_01577	3.65e-15	-	-	-	-	-	-	-	-
IPFFCMEA_01578	8.95e-71	-	-	-	L	-	-	-	transposase, IS605 OrfB family
IPFFCMEA_01579	4.02e-203	glxR	1.1.1.31	-	I	ko:K00020	ko00280,ko01100,map00280,map01100	ko00000,ko00001,ko01000	COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IPFFCMEA_01580	0.0	mcpC	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_01581	6.21e-162	ykwB	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_01582	5.86e-255	splB	4.1.99.14	-	L	ko:K03716	-	ko00000,ko01000	Spore photoproduct lyase
IPFFCMEA_01583	1.54e-51	splA	-	-	S	ko:K06315	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_01584	0.0	ptsI	2.7.3.9	-	G	ko:K08483	ko02060,map02060	ko00000,ko00001,ko01000,ko02000	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IPFFCMEA_01585	1.51e-53	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	phosphocarrier protein HPr
IPFFCMEA_01586	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_01587	4.23e-110	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IPFFCMEA_01588	1.25e-41	glcT	-	-	K	ko:K03480,ko:K03488	-	ko00000,ko03000	antiterminator
IPFFCMEA_01589	2.21e-228	ykvZ	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01590	3.19e-263	ykvY	3.4.13.9	-	E	ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IPFFCMEA_01591	3.99e-09	-	-	-	-	-	-	-	-
IPFFCMEA_01592	0.0	zosA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IPFFCMEA_01593	1.12e-114	stoA	-	-	CO	-	-	-	thiol-disulfide
IPFFCMEA_01594	6.46e-302	ykvU	-	-	S	-	-	-	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPFFCMEA_01595	1.83e-141	ykvT	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell Wall Hydrolase
IPFFCMEA_01596	2.6e-39	-	-	-	-	-	-	-	-
IPFFCMEA_01597	5.43e-35	ykvS	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_01598	8.95e-61	ykvR	-	-	S	-	-	-	Protein of unknown function (DUF3219)
IPFFCMEA_01599	2.36e-125	queF	1.7.1.13	-	S	ko:K09457	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IPFFCMEA_01600	2.41e-177	queE	4.3.99.3	-	H	ko:K10026	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IPFFCMEA_01601	6.96e-105	queD	4.1.2.50, 4.2.3.12	-	H	ko:K01737	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000,ko03016	synthase
IPFFCMEA_01602	2.61e-160	queC	6.3.4.20	-	F	ko:K06920	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000,ko03016	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IPFFCMEA_01603	8.23e-228	ykvI	-	-	S	-	-	-	membrane
IPFFCMEA_01604	0.0	clpE	-	-	O	ko:K03697,ko:K04086	-	ko00000,ko03110	Belongs to the ClpA ClpB family
IPFFCMEA_01605	9.19e-177	motA	-	-	N	ko:K02556	ko02020,ko02030,ko02040,map02020,map02030,map02040	ko00000,ko00001,ko02000,ko02035	flagellar motor
IPFFCMEA_01606	1.51e-166	motB	-	-	N	ko:K02557	ko02030,ko02040,map02030,map02040	ko00000,ko00001,ko02000,ko02035	Flagellar motor protein
IPFFCMEA_01607	5.17e-99	ykvE	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IPFFCMEA_01608	0.0	kinD	2.7.13.3	-	T	ko:K13532	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IPFFCMEA_01609	5.87e-74	eag	-	-	-	-	-	-	-
IPFFCMEA_01611	8.82e-68	-	-	-	S	-	-	-	Protein of unknown function (DUF1232)
IPFFCMEA_01612	1.02e-121	mtnD	1.13.11.53, 1.13.11.54	-	S	ko:K08967	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IPFFCMEA_01613	1.24e-144	mtnB	4.2.1.109	-	E	ko:K08964	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IPFFCMEA_01614	7.2e-175	mtnX	3.1.3.87	-	E	ko:K08966	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IPFFCMEA_01615	2.79e-294	mtnW	5.3.2.5	-	G	ko:K08965	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IPFFCMEA_01616	6.84e-296	mtnE	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IPFFCMEA_01617	3.86e-191	mtnU	3.5.1.3	-	S	ko:K13566	ko00250,map00250	ko00000,ko00001,ko01000	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IPFFCMEA_01618	7.07e-293	mtnK	2.7.1.100	-	F	ko:K00899	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IPFFCMEA_01619	3.8e-252	mtnA	5.3.1.23	-	E	ko:K08963	ko00270,ko01100,map00270,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IPFFCMEA_01621	2.76e-115	ogt	2.1.1.63	-	L	ko:K00567,ko:K13531	-	ko00000,ko01000,ko03400	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPFFCMEA_01622	0.0	kinE	2.7.13.3	-	T	ko:K13533	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_01623	4.75e-244	ykrP	-	-	G	-	-	-	COG3594 Fucose 4-O-acetylase and related acetyltransferases
IPFFCMEA_01624	4.83e-30	ykzE	-	-	-	-	-	-	-
IPFFCMEA_01626	1.82e-310	ktrD	-	-	P	-	-	-	COG0168 Trk-type K transport systems, membrane components
IPFFCMEA_01627	3.97e-199	htpX	-	-	O	ko:K03799	-	ko00000,ko00002,ko01000,ko01002	Belongs to the peptidase M48B family
IPFFCMEA_01628	7.68e-160	ykrK	-	-	S	-	-	-	Domain of unknown function (DUF1836)
IPFFCMEA_01629	1.4e-36	sspD	-	-	S	ko:K06421	-	ko00000	small acid-soluble spore protein
IPFFCMEA_01630	3.83e-204	rsgI	-	-	S	-	-	-	Anti-sigma factor N-terminus
IPFFCMEA_01631	1.8e-167	sigI	-	-	K	ko:K03093	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_01632	1.33e-226	ykoY	-	-	P	-	-	-	COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IPFFCMEA_01633	1.71e-143	ykoX	-	-	S	-	-	-	membrane-associated protein
IPFFCMEA_01634	0.0	ykoW	2.7.7.65	-	T	ko:K21023	ko02025,map02025	ko00000,ko00001,ko01000	Diguanylate cyclase
IPFFCMEA_01635	7.24e-204	ku	-	-	L	ko:K10979	ko03450,map03450	ko00000,ko00001,ko03400	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IPFFCMEA_01636	0.0	ligD	6.5.1.1	-	L	ko:K01971	ko03450,map03450	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA ligase
IPFFCMEA_01637	9.49e-238	ykoT	-	-	M	-	-	-	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPFFCMEA_01638	0.0	ykoS	-	-	-	-	-	-	-
IPFFCMEA_01639	1.2e-195	ykoQ	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IPFFCMEA_01640	2.57e-122	ykoP	-	-	G	-	-	-	polysaccharide deacetylase
IPFFCMEA_01641	6.33e-277	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
IPFFCMEA_01642	9.83e-106	ykoM	-	-	K	ko:K15973	-	ko00000,ko03000	transcriptional
IPFFCMEA_01643	3.04e-36	ykoL	-	-	-	-	-	-	-
IPFFCMEA_01644	1.63e-25	-	-	-	-	-	-	-	-
IPFFCMEA_01645	1.49e-70	tnrA	-	-	K	-	-	-	transcriptional
IPFFCMEA_01646	9.86e-300	mgtE	-	-	P	ko:K06213	-	ko00000,ko02000	Acts as a magnesium transporter
IPFFCMEA_01648	1.45e-08	-	-	-	-	-	-	-	-
IPFFCMEA_01649	1.3e-111	ykoJ	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IPFFCMEA_01650	7.88e-145	ykoI	-	-	S	-	-	-	Peptidase propeptide and YPEB domain
IPFFCMEA_01651	6.05e-307	ykoH	-	-	T	-	-	-	Histidine kinase
IPFFCMEA_01652	1.68e-156	ykoG	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_01653	4.05e-141	ykoF	-	-	S	-	-	-	YKOF-related Family
IPFFCMEA_01654	3.99e-127	ykoE	-	-	S	ko:K16925	-	ko00000,ko00002,ko02000	ABC-type cobalt transport system, permease component
IPFFCMEA_01655	0.0	ykoD	-	-	P	ko:K16786,ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_01656	5.18e-173	ykoC	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Cobalt transport protein
IPFFCMEA_01657	3.99e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPFFCMEA_01658	6.07e-225	isp	-	-	O	ko:K13275	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPFFCMEA_01659	0.0	metE	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IPFFCMEA_01660	5.67e-115	guaD	3.5.4.3	-	FJ	ko:K01487	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	COG0590 Cytosine adenosine deaminases
IPFFCMEA_01661	4.72e-93	ohrB	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IPFFCMEA_01662	1.66e-96	ohrR	-	-	K	-	-	-	COG1846 Transcriptional regulators
IPFFCMEA_01663	2.39e-93	ohrA	-	-	O	-	-	-	Organic hydroperoxide resistance protein
IPFFCMEA_01664	4.59e-289	proA	1.2.1.41	-	E	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IPFFCMEA_01665	3.68e-256	proB	2.7.2.11	-	E	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IPFFCMEA_01666	1.66e-217	purU	3.5.1.10	-	F	ko:K01433	ko00630,ko00670,map00630,map00670	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IPFFCMEA_01667	1.94e-66	ykkD	-	-	P	ko:K18925	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IPFFCMEA_01668	2.99e-71	ykkC	-	-	P	ko:K18924	-	ko00000,ko00002,ko02000	Multidrug resistance protein
IPFFCMEA_01669	2.34e-124	ykkB	-	-	J	-	-	-	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPFFCMEA_01670	2.51e-125	ykkA	-	-	S	-	-	-	Protein of unknown function (DUF664)
IPFFCMEA_01671	1.32e-165	ykjA	-	-	S	-	-	-	Protein of unknown function (DUF421)
IPFFCMEA_01672	9.93e-15	-	-	-	-	-	-	-	-
IPFFCMEA_01673	4.21e-286	hmp	1.14.12.17, 1.18.1.3	-	C	ko:K05916,ko:K15765	ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132	ko00000,ko00001,ko00002,ko01000	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IPFFCMEA_01674	5.42e-120	ykhA	-	-	I	-	-	-	Acyl-CoA hydrolase
IPFFCMEA_01675	9.79e-102	ykgA	-	-	E	-	-	-	Amidinotransferase
IPFFCMEA_01676	5.69e-261	pgl	3.1.1.31	-	G	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	6-phosphogluconolactonase
IPFFCMEA_01677	8.44e-237	ykfD	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_01678	4.03e-207	ykfC	3.4.14.13	-	M	ko:K20742	-	ko00000,ko01000,ko01002	COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IPFFCMEA_01679	3.21e-251	ykfB	5.1.1.20	-	M	ko:K19802	-	ko00000,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IPFFCMEA_01680	5.33e-222	ykfA	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	proteins, homologs of microcin C7 resistance protein MccF
IPFFCMEA_01682	0.0	dppE	-	-	E	ko:K16199	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IPFFCMEA_01683	7.78e-236	dppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_01684	8.28e-222	dppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPFFCMEA_01685	9.7e-204	dppB	-	-	P	ko:K16200	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPFFCMEA_01686	1.4e-196	dppA	-	-	E	ko:K16203	-	ko00000,ko01000,ko01002	D-aminopeptidase
IPFFCMEA_01687	4.95e-180	proG	1.5.1.2	-	E	ko:K00286,ko:K02239	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko02044	Pyrroline-5-carboxylate reductase
IPFFCMEA_01688	2.73e-287	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPFFCMEA_01690	1.28e-228	ykcC	-	GT2	M	ko:K20534	-	ko00000,ko01000,ko01005,ko02000	COG0463 Glycosyltransferases involved in cell wall biogenesis
IPFFCMEA_01691	0.0	ykcB	-	-	M	-	-	-	COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IPFFCMEA_01692	8.07e-233	ykcA	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IPFFCMEA_01693	7.38e-309	steT	-	-	E	ko:K03294	-	ko00000	amino acid
IPFFCMEA_01694	1.85e-144	ykaA	-	-	P	ko:K07220	-	ko00000	COG1392 Phosphate transport regulator (distant homolog of PhoU)
IPFFCMEA_01695	1.54e-225	pit	-	-	P	ko:K03306	-	ko00000	phosphate transporter
IPFFCMEA_01696	1.19e-175	spoIISA	-	-	S	ko:K06388	-	ko00000	Toxin SpoIISA, type II toxin-antitoxin system
IPFFCMEA_01697	1.78e-31	spoIISB	-	-	S	ko:K06389	-	ko00000	Stage II sporulation protein SB
IPFFCMEA_01698	3.2e-209	xlyA	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	n-acetylmuramoyl-L-alanine amidase
IPFFCMEA_01699	1.15e-52	xhlB	-	-	S	-	-	-	SPP1 phage holin
IPFFCMEA_01700	2.21e-51	xhlA	-	-	S	-	-	-	Haemolysin XhlA
IPFFCMEA_01701	9.79e-195	xepA	-	-	-	-	-	-	-
IPFFCMEA_01702	6.35e-31	xkdX	-	-	-	-	-	-	-
IPFFCMEA_01703	2.7e-68	xkdW	-	-	S	-	-	-	XkdW protein
IPFFCMEA_01704	0.0	-	-	-	-	-	-	-	-
IPFFCMEA_01705	4.43e-56	-	-	-	-	-	-	-	-
IPFFCMEA_01706	3.92e-135	-	-	-	S	-	-	-	Uncharacterised protein conserved in bacteria (DUF2313)
IPFFCMEA_01707	7.59e-245	-	-	-	S	-	-	-	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IPFFCMEA_01708	3.82e-90	xkdS	-	-	S	-	-	-	Protein of unknown function (DUF2634)
IPFFCMEA_01709	4.32e-53	xkdR	-	-	S	-	-	-	Protein of unknown function (DUF2577)
IPFFCMEA_01710	2.31e-232	xkdQ	-	-	G	-	-	-	NLP P60 protein
IPFFCMEA_01711	1.73e-151	xkdP	-	-	S	-	-	-	Lysin motif
IPFFCMEA_01712	0.0	xkdO	-	-	L	-	-	-	Transglycosylase SLT domain
IPFFCMEA_01713	9.21e-99	-	-	-	S	-	-	-	Phage XkdN-like tail assembly chaperone protein, TAC
IPFFCMEA_01714	2.45e-98	xkdM	-	-	S	-	-	-	Phage tail tube protein
IPFFCMEA_01715	0.0	xkdK	-	-	S	-	-	-	Phage tail sheath C-terminal domain
IPFFCMEA_01716	2.87e-101	xkdJ	-	-	-	-	-	-	-
IPFFCMEA_01717	5.84e-115	xkdI	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IPFFCMEA_01718	1.05e-85	yqbH	-	-	S	-	-	-	Domain of unknown function (DUF3599)
IPFFCMEA_01719	3.85e-81	yqbG	-	-	S	-	-	-	Protein of unknown function (DUF3199)
IPFFCMEA_01720	3.91e-217	xkdG	-	-	S	-	-	-	Phage capsid family
IPFFCMEA_01721	4.02e-176	xkdF3	-	-	L	-	-	-	Putative phage serine protease XkdF
IPFFCMEA_01722	0.0	yqbA	-	-	S	-	-	-	portal protein
IPFFCMEA_01723	0.0	xtmB	-	-	S	ko:K06909	-	ko00000	phage terminase, large subunit
IPFFCMEA_01724	1.18e-179	xtmA	-	-	L	ko:K07474	-	ko00000	phage terminase small subunit
IPFFCMEA_01725	8.12e-110	xpf	-	-	K	ko:K03088	-	ko00000,ko03021	COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IPFFCMEA_01730	8.72e-152	xkdC	-	-	L	-	-	-	Bacterial dnaA protein
IPFFCMEA_01731	2.52e-201	xkdB	-	-	K	-	-	-	sequence-specific DNA binding
IPFFCMEA_01733	2.01e-74	xre	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_01734	1.53e-144	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IPFFCMEA_01735	4.54e-204	yjqC	-	-	P	ko:K07217	-	ko00000	Catalase
IPFFCMEA_01736	1.11e-138	yjqB	-	-	S	-	-	-	Pfam:DUF867
IPFFCMEA_01737	1.35e-80	yjqA	-	-	S	-	-	-	Bacterial PH domain
IPFFCMEA_01738	3.09e-217	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IPFFCMEA_01739	1.09e-34	-	-	-	S	-	-	-	YCII-related domain
IPFFCMEA_01741	8.59e-272	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_01742	1.9e-177	ycsE	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Sucrose-6F-phosphate phosphohydrolase
IPFFCMEA_01743	1.1e-180	ycsF	-	-	S	ko:K07160	-	ko00000	Belongs to the UPF0271 (lamB) family
IPFFCMEA_01744	1.87e-271	ycsG	-	-	P	-	-	-	COG1914 Mn2 and Fe2 transporters of the NRAMP family
IPFFCMEA_01745	7e-190	ycsI	-	-	S	-	-	-	Belongs to the D-glutamate cyclase family
IPFFCMEA_01746	9.77e-171	kipI	-	-	E	ko:K06351	-	ko00000	Allophanate hydrolase subunit 1
IPFFCMEA_01747	1.99e-238	kipA	-	-	E	ko:K06350	-	ko00000	Allophanate hydrolase subunit 2
IPFFCMEA_01748	1.55e-170	kipR	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01749	5.94e-154	ycsK	-	-	E	-	-	-	anatomical structure formation involved in morphogenesis
IPFFCMEA_01751	8.97e-65	yczJ	-	-	S	-	-	-	biosynthesis
IPFFCMEA_01752	0.0	pbpC	3.4.16.4	-	M	ko:K02545,ko:K21467	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko00002,ko01000,ko01011,ko01504	Penicillin-binding Protein
IPFFCMEA_01753	8.6e-220	ycsN	-	-	S	-	-	-	Oxidoreductase
IPFFCMEA_01754	0.0	mtlR	-	-	K	ko:K03483	-	ko00000,ko03000	transcriptional regulator, MtlR
IPFFCMEA_01755	0.0	ydaB	-	-	IQ	-	-	-	acyl-CoA ligase
IPFFCMEA_01756	1e-127	ydaC	-	-	Q	-	-	-	Methyltransferase domain
IPFFCMEA_01757	3.74e-207	ydaD	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_01758	2.36e-126	ydaE	5.3.1.15	-	S	ko:K09988	ko00040,map00040	ko00000,ko00001,ko01000	Cupin 2, conserved barrel domain protein
IPFFCMEA_01759	8.32e-128	ydaF	-	-	J	ko:K03817	-	ko00000,ko01000,ko03009	COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IPFFCMEA_01760	6.13e-100	ydaG	-	-	S	-	-	-	general stress protein
IPFFCMEA_01761	5.12e-176	amj	-	-	U	-	-	-	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IPFFCMEA_01762	5.19e-60	ydzA	-	-	EGP	-	-	-	Domain of unknown function (DUF3817)
IPFFCMEA_01763	3.95e-98	lrpC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IPFFCMEA_01764	0.0	topB	5.99.1.2	-	L	ko:K03169	-	ko00000,ko01000,ko03032	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IPFFCMEA_01765	5.12e-101	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	Belongs to the Nudix hydrolase family
IPFFCMEA_01766	0.0	ydaP	1.2.3.3	-	EH	ko:K00158	ko00620,ko01100,map00620,map01100	ko00000,ko00001,ko01000	Belongs to the TPP enzyme family
IPFFCMEA_01767	1.84e-34	-	-	-	-	-	-	-	-
IPFFCMEA_01768	2.18e-90	sdpB	-	-	S	-	-	-	Protein conserved in bacteria
IPFFCMEA_01770	6.14e-53	-	-	-	-	-	-	-	-
IPFFCMEA_01771	7.87e-286	mntH	-	-	P	ko:K03322	-	ko00000,ko02000	H( )-stimulated, divalent metal cation uptake system
IPFFCMEA_01772	1.67e-42	ydaS	-	-	S	-	-	-	membrane
IPFFCMEA_01773	7.54e-99	ydaT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2188)
IPFFCMEA_01774	4.3e-190	ydbA	-	-	P	-	-	-	EcsC protein family
IPFFCMEA_01775	8.37e-11	gsiB	-	-	S	ko:K06884	-	ko00000	general stress protein
IPFFCMEA_01776	2.17e-78	ydbB	-	-	G	-	-	-	Cupin domain
IPFFCMEA_01777	1.49e-81	ydbC	-	-	S	-	-	-	Domain of unknown function (DUF4937
IPFFCMEA_01778	6.41e-197	ydbD	-	-	P	ko:K07217	-	ko00000	Catalase
IPFFCMEA_01779	4.99e-251	dctB	-	-	G	-	-	-	COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IPFFCMEA_01780	0.0	dctS	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IPFFCMEA_01781	3.39e-155	dctR	-	-	T	ko:K02475,ko:K11692	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IPFFCMEA_01782	7.33e-289	dctA	-	-	U	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPFFCMEA_01783	1.32e-230	ydbI	-	-	S	-	-	-	AI-2E family transporter
IPFFCMEA_01784	2.66e-218	ydbJ	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_01785	2.99e-159	ydbK	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPFFCMEA_01786	9.32e-70	ydbL	-	-	-	-	-	-	-
IPFFCMEA_01787	1.83e-280	ydbM	-	-	I	-	-	-	acyl-CoA dehydrogenase
IPFFCMEA_01788	1.49e-26	-	-	-	S	-	-	-	Fur-regulated basic protein B
IPFFCMEA_01790	2.72e-202	yeaB	-	-	P	-	-	-	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IPFFCMEA_01791	4.19e-75	ydbP	-	-	CO	-	-	-	Thioredoxin
IPFFCMEA_01792	4.18e-256	ddl	6.3.2.4	-	F	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Belongs to the D-alanine--D-alanine ligase family
IPFFCMEA_01793	0.0	murF	6.3.2.10	-	M	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IPFFCMEA_01794	0.0	cshA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IPFFCMEA_01795	2.12e-107	ydbS	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IPFFCMEA_01796	0.0	ydbT	-	-	S	ko:K08981	-	ko00000	Membrane
IPFFCMEA_01797	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)
IPFFCMEA_01798	1.87e-76	acpS	2.7.8.7	-	I	ko:K00997	ko00770,map00770	ko00000,ko00001,ko01000	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IPFFCMEA_01799	4.66e-234	ydcC	-	-	M	-	-	-	COG2834 Outer membrane lipoprotein-sorting protein
IPFFCMEA_01800	2.07e-281	alr	5.1.1.1, 5.1.1.5	-	E	ko:K01775,ko:K20707	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPFFCMEA_01801	9.49e-57	ndoAI	-	-	K	ko:K07723	-	ko00000,ko02048,ko03000	transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IPFFCMEA_01802	4.34e-75	ndoA	-	-	L	ko:K07171	-	ko00000,ko01000,ko02048	Toxic component of a toxin-antitoxin (TA) module
IPFFCMEA_01803	8.58e-184	rsbR	-	-	T	ko:K17763	-	ko00000,ko03021	Positive regulator of sigma-B
IPFFCMEA_01804	1.8e-74	rsbS	-	-	T	ko:K17762	-	ko00000,ko03021	antagonist
IPFFCMEA_01805	1e-88	rsbT	2.7.11.1	-	T	ko:K17752	-	ko00000,ko01000,ko01001,ko03021	COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IPFFCMEA_01806	1.08e-242	rsbU	3.1.3.3	-	KT	ko:K07315	-	ko00000,ko01000,ko03021	phosphatase
IPFFCMEA_01807	1.97e-70	rsbV	-	-	T	ko:K04749	-	ko00000,ko03021	Belongs to the anti-sigma-factor antagonist family
IPFFCMEA_01808	2.48e-111	rsbW	2.7.11.1	-	F	ko:K04757	-	ko00000,ko01000,ko01001,ko03021	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IPFFCMEA_01809	1.55e-178	sigB	-	-	K	ko:K03090	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_01810	1.86e-141	rsbX	3.1.3.3	-	KT	ko:K05518	-	ko00000,ko01000,ko03021	Sigma factor PP2C-like phosphatases
IPFFCMEA_01811	0.0	tex	-	-	K	ko:K06959	-	ko00000	COG2183 Transcriptional accessory protein
IPFFCMEA_01812	3.74e-108	ydcK	-	-	S	ko:K03095	-	ko00000	Belongs to the SprT family
IPFFCMEA_01820	4.46e-153	-	-	-	E	-	-	-	amino acid
IPFFCMEA_01821	9.13e-135	ywqM	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_01822	4.64e-95	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_01823	9.99e-59	-	-	-	-	-	-	-	-
IPFFCMEA_01824	5.9e-171	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPFFCMEA_01825	1.8e-45	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IPFFCMEA_01826	2.98e-53	-	-	-	-	-	-	-	-
IPFFCMEA_01830	3.49e-145	ydeA	-	-	S	-	-	-	DJ-1/PfpI family
IPFFCMEA_01831	4.22e-41	cspL	-	-	K	ko:K03704	-	ko00000,ko03000	Cold shock
IPFFCMEA_01832	1.45e-102	ydeB	-	-	K	ko:K07736	-	ko00000,ko03000	Transcription factor
IPFFCMEA_01835	1.55e-235	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IPFFCMEA_01838	3.96e-182	yvaG	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_01839	8.9e-131	-	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IPFFCMEA_01840	2.04e-70	yvaE	-	-	P	ko:K03297	-	ko00000,ko02000	Small Multidrug Resistance protein
IPFFCMEA_01841	1.94e-95	yvaD	-	-	S	-	-	-	Family of unknown function (DUF5360)
IPFFCMEA_01842	0.0	-	-	-	S	-	-	-	Fusaric acid resistance protein-like
IPFFCMEA_01843	7.68e-25	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPFFCMEA_01844	2.92e-88	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPFFCMEA_01845	1.99e-247	yvaA	1.1.1.371	-	S	ko:K16044	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IPFFCMEA_01846	6.89e-65	csoR	-	-	S	ko:K21600	-	ko00000,ko03000	transcriptional
IPFFCMEA_01847	3.02e-40	copZ	-	-	P	ko:K07213	ko04978,map04978	ko00000,ko00001	Copper resistance protein CopZ
IPFFCMEA_01848	0.0	copA	3.6.3.54	-	P	ko:K17686	ko01524,ko04016,map01524,map04016	ko00000,ko00001,ko01000	P-type ATPase
IPFFCMEA_01849	8.72e-100	ctsR	-	-	K	ko:K03708	-	ko00000,ko03000	Belongs to the CtsR family
IPFFCMEA_01850	2.36e-74	mcsA	-	-	S	ko:K19411	-	ko00000	protein with conserved CXXC pairs
IPFFCMEA_01851	7.74e-257	mcsB	2.7.14.1	-	E	ko:K19405	-	ko00000,ko01000	Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IPFFCMEA_01852	0.0	clpC	-	-	O	ko:K03696	ko01100,map01100	ko00000,ko03110	Belongs to the ClpA ClpB family
IPFFCMEA_01853	0.0	radA	-	-	O	ko:K04485	-	ko00000,ko03400	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPFFCMEA_01854	3.8e-251	disA	2.7.7.85	-	L	ko:K07067	-	ko00000,ko01000	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IPFFCMEA_01855	2.57e-252	yacL	-	-	S	-	-	-	COG4956 Integral membrane protein (PIN domain superfamily)
IPFFCMEA_01856	3.02e-161	ispD	2.7.7.60	-	I	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IPFFCMEA_01857	1.82e-112	ispF	2.7.7.60, 4.6.1.12	-	I	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IPFFCMEA_01858	0.0	gltX	6.1.1.24	-	J	ko:K09698	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPFFCMEA_01859	5.46e-152	cysE	2.3.1.30	-	E	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	ko00000,ko00001,ko00002,ko01000	Serine acetyltransferase
IPFFCMEA_01860	0.0	cysS	6.1.1.16	-	J	ko:K01883	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-I aminoacyl-tRNA synthetase family
IPFFCMEA_01861	3.52e-96	mrnC	-	-	J	ko:K11145	-	ko00000,ko01000,ko03009	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IPFFCMEA_01862	8.65e-174	trmH	2.1.1.185	-	J	ko:K03218	-	ko00000,ko01000,ko03009	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPFFCMEA_01863	3.31e-114	yacP	-	-	S	ko:K06962	-	ko00000	RNA-binding protein containing a PIN domain
IPFFCMEA_01864	3.27e-149	sigH	-	-	K	ko:K03088,ko:K03091,ko:K12296	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko03000,ko03021	Belongs to the sigma-70 factor family
IPFFCMEA_01865	2.65e-32	secE	-	-	U	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IPFFCMEA_01866	1.37e-124	nusG	-	-	K	ko:K02601	-	ko00000,ko03009,ko03021	Participates in transcription elongation, termination and antitermination
IPFFCMEA_01867	3.4e-93	rplK	-	-	J	ko:K02867	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPFFCMEA_01868	1.82e-162	rplA	-	-	J	ko:K02863	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IPFFCMEA_01869	1.64e-103	rplJ	-	-	J	ko:K02864	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPFFCMEA_01870	2.84e-64	rplL	-	-	J	ko:K02935	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IPFFCMEA_01871	2.43e-138	rsmC	2.1.1.172	-	J	ko:K00564	-	ko00000,ko01000,ko03009	Methyltransferase
IPFFCMEA_01872	0.0	rpoB	2.7.7.6	-	K	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPFFCMEA_01873	0.0	rpoC	2.7.7.6	-	K	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPFFCMEA_01874	1.99e-44	rplGB	-	-	J	ko:K07590	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the eukaryotic ribosomal protein eL8 family
IPFFCMEA_01875	6.67e-94	rpsL	-	-	J	ko:K02950	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPFFCMEA_01876	4.85e-107	rpsG	-	-	J	ko:K02992	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IPFFCMEA_01877	0.0	fusA	-	-	J	ko:K02355	-	ko00000,ko03012,ko03029	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPFFCMEA_01878	1.36e-285	tuf	-	-	J	ko:K02358	-	ko00000,ko03012,ko03029,ko04147	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPFFCMEA_01879	1.83e-230	ybaC	-	-	S	-	-	-	Alpha/beta hydrolase family
IPFFCMEA_01880	2.58e-65	rpsJ	-	-	J	ko:K02946	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Involved in the binding of tRNA to the ribosomes
IPFFCMEA_01881	7.2e-144	rplC	-	-	J	ko:K02906	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPFFCMEA_01882	7.43e-136	rplD	-	-	J	ko:K02926	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Forms part of the polypeptide exit tunnel
IPFFCMEA_01883	3.27e-58	rplW	-	-	J	ko:K02892	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IPFFCMEA_01884	2.72e-200	rplB	-	-	J	ko:K02886	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPFFCMEA_01885	2.83e-62	rpsS	-	-	J	ko:K02965	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPFFCMEA_01886	9.23e-71	rplV	-	-	J	ko:K02890	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPFFCMEA_01887	5.9e-152	rpsC	-	-	J	ko:K02982	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPFFCMEA_01888	1.96e-98	rplP	-	-	J	ko:K02878	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPFFCMEA_01889	1.88e-35	rpmC	-	-	J	ko:K02904	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uL29 family
IPFFCMEA_01890	1.64e-52	rpsQ	-	-	J	ko:K02961	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPFFCMEA_01891	3.62e-79	rplN	-	-	J	ko:K02874	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPFFCMEA_01892	1.43e-67	rplX	-	-	J	ko:K02895	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPFFCMEA_01893	7.72e-122	rplE	-	-	J	ko:K02931	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPFFCMEA_01894	1.43e-39	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPFFCMEA_01895	3.11e-87	rpsH	-	-	J	ko:K02994	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPFFCMEA_01896	4.47e-121	rplF	-	-	J	ko:K02933	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPFFCMEA_01897	2.89e-75	rplR	-	-	J	ko:K02881	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPFFCMEA_01898	9.16e-111	rpsE	-	-	J	ko:K02988	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPFFCMEA_01899	1.59e-33	rpmD	-	-	J	ko:K02907	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L30
IPFFCMEA_01900	7.32e-95	rplO	-	-	J	ko:K02876	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	binds to the 23S rRNA
IPFFCMEA_01901	5.7e-298	secY	-	-	U	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IPFFCMEA_01902	2.51e-157	adk	2.7.4.3	-	F	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IPFFCMEA_01903	2.32e-182	map	3.4.11.18	-	E	ko:K01265	-	ko00000,ko01000,ko01002	Methionine aminopeptidase
IPFFCMEA_01904	2.92e-46	infA	-	-	J	ko:K02518	-	ko00000,ko03012	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPFFCMEA_01905	2.45e-19	rpmJ	-	-	J	ko:K02919	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL36 family
IPFFCMEA_01906	1.09e-75	rpsM	-	-	J	ko:K02952	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IPFFCMEA_01907	3.24e-84	rpsK	-	-	J	ko:K02948	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPFFCMEA_01908	7.01e-217	rpoA	2.7.7.6	-	K	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPFFCMEA_01909	4.27e-77	rplQ	-	-	J	ko:K02879	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein L17
IPFFCMEA_01910	3.05e-199	ecfA1	-	-	P	ko:K16786	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPFFCMEA_01911	2.69e-197	ecfA2	-	-	P	ko:K16787	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPFFCMEA_01912	4.39e-175	ecfT	-	-	P	ko:K16785	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IPFFCMEA_01913	2.51e-181	truA	5.4.99.12	-	J	ko:K06173	-	ko00000,ko01000,ko03016	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IPFFCMEA_01914	1.13e-102	rplM	-	-	J	ko:K02871	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPFFCMEA_01915	4.28e-84	rpsI	-	-	J	ko:K02996	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the universal ribosomal protein uS9 family
IPFFCMEA_01916	1.45e-184	ybaJ	-	-	Q	-	-	-	Methyltransferase domain
IPFFCMEA_01917	2.54e-91	ybaK	-	-	S	-	-	-	Protein of unknown function (DUF2521)
IPFFCMEA_01918	2.22e-170	cwlD	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IPFFCMEA_01919	1.1e-255	mrp	-	-	D	ko:K03593	-	ko00000,ko03029,ko03036	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IPFFCMEA_01920	1.04e-122	gerD	-	-	-	ko:K06294	-	ko00000	-
IPFFCMEA_01921	5.95e-133	kbaA	-	-	S	ko:K06349	-	ko00000	Involved in the activation of the KinB signaling pathway of sporulation
IPFFCMEA_01922	4.31e-181	pdaB	-	-	G	-	-	-	Polysaccharide deacetylase
IPFFCMEA_01923	2.11e-251	galE	5.1.3.2	-	M	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family
IPFFCMEA_01924	3.81e-100	-	-	-	S	-	-	-	Protein of unknown function (DUF1453)
IPFFCMEA_01925	1.76e-166	-	-	-	T	-	-	-	Signal transduction histidine kinase
IPFFCMEA_01926	8.24e-73	-	-	-	T	-	-	-	Signal transduction histidine kinase
IPFFCMEA_01927	2.69e-148	-	-	-	K	ko:K02479	-	ko00000,ko02022	helix_turn_helix, Lux Regulon
IPFFCMEA_01928	1.83e-297	pepT	3.4.11.4	-	E	ko:K01258	-	ko00000,ko01000,ko01002	Cleaves the N-terminal amino acid of tripeptides
IPFFCMEA_01930	2.88e-111	yxjI	-	-	S	-	-	-	LURP-one-related
IPFFCMEA_01931	2.13e-277	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IPFFCMEA_01932	2.21e-275	yxjG	2.1.1.14	-	E	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Methionine synthase
IPFFCMEA_01933	1.67e-175	yxjF	1.1.1.30	-	IQ	ko:K00019	ko00072,ko00650,ko01100,map00072,map00650,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IPFFCMEA_01934	1.69e-150	scoB	2.8.3.5	-	I	ko:K01029	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPFFCMEA_01935	6.6e-168	scoA	2.8.3.5	-	I	ko:K01028	ko00072,ko00280,ko00650,map00072,map00280,map00650	ko00000,ko00001,ko01000	COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IPFFCMEA_01936	0.0	yxjC	-	-	EG	-	-	-	COG2610 H gluconate symporter and related permeases
IPFFCMEA_01937	9.07e-197	yxjB	2.1.1.187	-	Q	ko:K00563	-	ko00000,ko01000,ko03009	Methyltransferase domain
IPFFCMEA_01938	3.47e-268	nupG	-	-	F	ko:K16323	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPFFCMEA_01939	1.51e-91	-	-	-	T	-	-	-	Domain of unknown function (DUF4163)
IPFFCMEA_01940	2.28e-63	yxiS	-	-	-	-	-	-	-
IPFFCMEA_01941	0.0	katE	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IPFFCMEA_01942	2e-284	citH	-	-	C	ko:K03300,ko:K11639	ko02020,map02020	ko00000,ko00001	Citrate transporter
IPFFCMEA_01943	7.21e-183	bglS	-	-	M	-	-	-	licheninase activity
IPFFCMEA_01944	5.66e-193	licT	-	-	K	ko:K03488	-	ko00000,ko03000	transcriptional antiterminator
IPFFCMEA_01945	7.23e-141	-	-	-	-	-	-	-	-
IPFFCMEA_01946	3.8e-292	yxiO	-	-	S	ko:K06902	ko04138,map04138	ko00000,ko00001,ko02000,ko04131	COG2270 Permeases of the major facilitator superfamily
IPFFCMEA_01947	0.0	dbpA	3.6.4.13	-	JKL	ko:K05592	ko03018,map03018	ko00000,ko00001,ko01000,ko03009,ko03019	DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IPFFCMEA_01948	3.52e-274	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPFFCMEA_01951	4.06e-58	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IPFFCMEA_01954	1.86e-40	-	-	-	-	-	-	-	-
IPFFCMEA_01955	8.21e-50	yxiI	-	-	S	-	-	-	Protein of unknown function (DUF2716)
IPFFCMEA_01956	3.42e-173	-	-	-	-	-	-	-	-
IPFFCMEA_01959	6.09e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF2750)
IPFFCMEA_01960	9.7e-68	yxxG	-	-	-	-	-	-	-
IPFFCMEA_01961	4.67e-89	yxiG	-	-	-	-	-	-	-
IPFFCMEA_01962	4.48e-58	-	-	-	-	-	-	-	-
IPFFCMEA_01963	7.13e-100	-	-	-	-	-	-	-	-
IPFFCMEA_01964	8.9e-119	-	-	-	S	-	-	-	Protein of unknown function (DUF4240)
IPFFCMEA_01965	5.06e-175	-	-	-	-	-	-	-	-
IPFFCMEA_01967	1.27e-69	-	-	-	-	-	-	-	-
IPFFCMEA_01968	6.47e-100	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IPFFCMEA_01969	3.29e-19	yxiJ	-	-	S	-	-	-	YxiJ-like protein
IPFFCMEA_01970	0.0	wapA	-	-	M	-	-	-	COG3209 Rhs family protein
IPFFCMEA_01971	5.69e-208	yxxF	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_01972	1.36e-160	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_01973	4.54e-157	-	1.14.11.45	-	E	ko:K20418	-	ko00000,ko01000	2OG-Fe dioxygenase
IPFFCMEA_01974	8.5e-95	yxiE	-	-	T	-	-	-	Belongs to the universal stress protein A family
IPFFCMEA_01975	8.86e-317	bglH	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IPFFCMEA_01976	1.56e-53	-	-	-	-	-	-	-	-
IPFFCMEA_01977	5.35e-102	-	-	-	S	ko:K21494	-	ko00000,ko02048	SMI1 / KNR4 family
IPFFCMEA_01978	0.0	-	-	-	S	ko:K21493	-	ko00000,ko01000,ko02048	nuclease activity
IPFFCMEA_01979	1.33e-52	yxiC	-	-	S	-	-	-	Family of unknown function (DUF5344)
IPFFCMEA_01980	5.38e-37	-	-	-	S	-	-	-	Domain of unknown function (DUF5082)
IPFFCMEA_01981	0.0	-	-	-	L	-	-	-	HKD family nuclease
IPFFCMEA_01982	1.23e-78	mutT	3.6.1.55	-	L	ko:K03574	-	ko00000,ko01000,ko03400	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IPFFCMEA_01983	2.01e-193	-	-	-	L	-	-	-	Protein of unknown function (DUF2726)
IPFFCMEA_01984	1.49e-308	yxiA	3.2.1.99	GH43	G	ko:K06113	-	ko00000,ko01000	Belongs to the glycosyl hydrolase 43 family
IPFFCMEA_01985	0.0	hutU	4.2.1.49	-	E	ko:K01712	ko00340,ko01100,map00340,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IPFFCMEA_01986	2.24e-204	ybgF	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPFFCMEA_01987	8.11e-299	pdp	2.4.2.2	-	F	ko:K00756	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	phosphorylase
IPFFCMEA_01988	1.92e-263	nupC	-	-	F	ko:K11535	-	ko00000,ko02000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPFFCMEA_01989	1.18e-149	deoC	4.1.2.4	-	F	ko:K01619	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IPFFCMEA_01990	7.06e-221	deoR	-	-	K	ko:K05346	-	ko00000,ko03000	COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IPFFCMEA_01991	8.39e-194	-	-	-	S	-	-	-	Domain of Unknown Function (DUF1206)
IPFFCMEA_01992	2.99e-249	eutH	-	-	E	ko:K04023	-	ko00000	Ethanolamine utilisation protein, EutH
IPFFCMEA_01993	0.0	yxeQ	-	-	S	-	-	-	MmgE/PrpD family
IPFFCMEA_01994	4.78e-271	yxeP	-	-	E	ko:K21613	-	ko00000,ko01000,ko01002	hydrolase activity
IPFFCMEA_01995	6.82e-171	yxeO	-	-	P	ko:K16960,ko:K16963	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_01996	3e-148	yxeN	-	-	P	ko:K10009,ko:K16962	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPFFCMEA_01997	4.3e-186	yxeM	-	-	M	ko:K16961	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IPFFCMEA_01998	6.03e-119	yxeL	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_01999	0.0	yxeK	-	-	C	-	-	-	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IPFFCMEA_02000	4.03e-239	yxeI	3.5.1.24	-	M	ko:K01442	ko00120,ko00121,ko01100,map00120,map00121,map01100	ko00000,ko00001,ko01000	Linear amide C-N hydrolases, choloylglycine hydrolase family
IPFFCMEA_02001	3.29e-193	yxeH	-	-	S	-	-	-	hydrolases of the HAD superfamily
IPFFCMEA_02004	5.99e-41	yxeE	-	-	-	-	-	-	-
IPFFCMEA_02005	7.57e-28	yxeD	-	-	-	-	-	-	-
IPFFCMEA_02006	2.17e-302	htrA	3.4.21.107	-	O	ko:K04771	ko01503,ko02020,map01503,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPFFCMEA_02007	6.4e-164	cssR	-	-	T	ko:K07770	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_02008	9.22e-317	cssS	2.7.13.3	-	T	ko:K07650	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_02009	3.06e-204	yuxN	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_02010	0.0	fumC	4.2.1.2	-	C	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	ko00000,ko00001,ko00002,ko01000	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IPFFCMEA_02011	1.06e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF3970)
IPFFCMEA_02012	0.0	gerAA	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IPFFCMEA_02013	7.95e-251	gerAB	-	-	E	ko:K06289,ko:K06292	-	ko00000,ko02000	Spore germination protein
IPFFCMEA_02014	5.54e-234	gerAC	-	-	S	ko:K06290,ko:K06293,ko:K06312	-	ko00000	Spore germination B3/ GerAC like, C-terminal
IPFFCMEA_02015	8.64e-137	vraR	-	-	KT	ko:K07694,ko:K11618	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_02016	3.34e-245	vraS	2.7.13.3	-	T	ko:K07681,ko:K11617	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_02017	5.39e-164	-	-	-	S	ko:K11622	ko02020,map02020	ko00000,ko00001	Cell wall-active antibiotics response 4TMS YvqF
IPFFCMEA_02018	5.74e-172	liaG	-	-	S	ko:K11621	ko02020,map02020	ko00000,ko00001	Putative adhesin
IPFFCMEA_02019	2.85e-142	liaH	-	-	KT	ko:K03969,ko:K11620	ko02020,map02020	ko00000,ko00001,ko00002	COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IPFFCMEA_02020	1.07e-82	liaI	-	-	S	ko:K11619	ko02020,map02020	ko00000,ko00001,ko00002	membrane
IPFFCMEA_02021	1.53e-286	yvqJ	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_02022	5.32e-129	yvqK	2.5.1.17	-	S	ko:K00798	ko00860,ko01100,map00860,map01100	ko00000,ko00001,ko00002,ko01000	Adenosyltransferase
IPFFCMEA_02023	5.43e-311	yvrA	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IPFFCMEA_02024	7.73e-236	btuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_02025	7.32e-219	btuF	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
IPFFCMEA_02026	2.89e-179	yvrD	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_02027	3.79e-219	yvrE	-	-	G	ko:K14274	ko00040,map00040	ko00000,ko00001,ko01000	SMP-30/Gluconolaconase/LRE-like region
IPFFCMEA_02028	0.0	yvrG	-	-	T	-	-	-	Histidine kinase
IPFFCMEA_02029	1.1e-170	yvrH	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_02030	5.07e-32	-	-	-	-	-	-	-	-
IPFFCMEA_02031	1.12e-124	yvrI	-	-	K	ko:K03093	-	ko00000,ko03021	RNA polymerase
IPFFCMEA_02032	3.46e-26	-	-	-	S	-	-	-	YvrJ protein family
IPFFCMEA_02033	3.76e-291	oxdC	4.1.1.2	-	G	ko:K01569	ko00630,ko01100,map00630,map01100	ko00000,ko00001,ko01000	Oxalate decarboxylase
IPFFCMEA_02034	9.89e-86	yvrL	-	-	S	-	-	-	Regulatory protein YrvL
IPFFCMEA_02035	2.21e-272	yvrN	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IPFFCMEA_02036	4.64e-159	yvrO	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_02037	3.44e-229	-	-	-	M	ko:K02005	-	ko00000	Efflux transporter rnd family, mfp subunit
IPFFCMEA_02038	2.92e-191	fhuC	3.6.3.34	-	HP	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter
IPFFCMEA_02039	4.78e-226	fhuG	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_02040	4.04e-235	fhuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_02041	2.57e-224	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_02043	0.0	yvsH	-	-	E	ko:K03294,ko:K03758	-	ko00000,ko02000	Arginine ornithine antiporter
IPFFCMEA_02044	9.37e-23	-	-	-	S	ko:K06427	-	ko00000	Small spore protein J (Spore_SspJ)
IPFFCMEA_02045	2.38e-109	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IPFFCMEA_02046	0.0	yvgJ	-	-	M	ko:K01138	-	ko00000,ko01000	Belongs to the LTA synthase family
IPFFCMEA_02047	2.97e-213	yvgK	-	-	P	ko:K07219	-	ko00000	COG1910 Periplasmic molybdate-binding protein domain
IPFFCMEA_02048	2.11e-175	modA	-	-	P	ko:K02020	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0725 ABC-type molybdate transport system, periplasmic component
IPFFCMEA_02049	1.01e-152	modB	-	-	P	ko:K02018	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4149 ABC-type molybdate transport system, permease component
IPFFCMEA_02050	6.19e-201	yvgN	-	-	S	-	-	-	reductase
IPFFCMEA_02051	9.32e-112	yvgO	-	-	-	-	-	-	-
IPFFCMEA_02052	0.0	yvgP	-	-	P	ko:K03316	-	ko00000	COG0025 NhaP-type Na H and K H antiporters
IPFFCMEA_02053	0.0	cysI	1.8.1.2, 1.8.7.1	-	P	ko:K00381,ko:K00392	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IPFFCMEA_02054	0.0	cysJ	1.8.1.2	-	P	ko:K00380	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IPFFCMEA_02055	0.0	helD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPFFCMEA_02057	6.7e-139	yvgT	-	-	S	-	-	-	membrane
IPFFCMEA_02058	1.99e-95	bdbC	-	-	O	ko:K03611	-	ko00000,ko03110	Required for disulfide bond formation in some proteins
IPFFCMEA_02059	3.45e-137	bdbD	-	-	O	-	-	-	Thioredoxin
IPFFCMEA_02060	0.0	cadA	3.6.3.3, 3.6.3.5	-	P	ko:K01534	-	ko00000,ko01000	COG2217 Cation transport ATPase
IPFFCMEA_02061	5.95e-212	menA	2.5.1.74	-	H	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	Belongs to the MenA family. Type 1 subfamily
IPFFCMEA_02062	0.0	dltA	6.1.1.13	-	Q	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_02063	1.14e-297	dltB	-	-	M	ko:K03739	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	membrane protein involved in D-alanine export
IPFFCMEA_02064	6.83e-50	dltC	6.1.1.13	-	IQ	ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01000,ko01504	Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_02065	4.09e-294	dltD	-	-	M	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	ko00000,ko00001,ko00002,ko01504	COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IPFFCMEA_02066	1.5e-60	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_02067	2.19e-07	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_02068	3.56e-43	dltE	-	-	M	ko:K14189	-	ko00000,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_02069	1.07e-263	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IPFFCMEA_02070	0.0	licH	3.2.1.86	GT4	G	ko:K01222	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IPFFCMEA_02071	8.33e-68	licA	2.7.1.196, 2.7.1.205	-	G	ko:K02759	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_02072	0.0	licC	-	-	G	ko:K02761	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko02000	The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IPFFCMEA_02073	1.89e-67	licB	2.7.1.196, 2.7.1.205	-	G	ko:K02760	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	transporter subunit IIB
IPFFCMEA_02074	0.0	licR	-	-	GKT	ko:K03491	-	ko00000,ko03000	Mga helix-turn-helix domain
IPFFCMEA_02075	1.05e-26	yxzF	-	-	-	-	-	-	-
IPFFCMEA_02076	3.23e-145	yxlJ	3.2.2.21	-	L	ko:K03652	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	Belongs to the DNA glycosylase MPG family
IPFFCMEA_02077	0.0	katX	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IPFFCMEA_02078	3.52e-274	yxlH	-	-	EGP	-	-	-	Major Facilitator Superfamily
IPFFCMEA_02079	1.14e-178	yxlG	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPFFCMEA_02080	3.33e-210	yxlF	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_02081	2.17e-39	yxlE	-	-	S	-	-	-	Phospholipase_D-nuclease N-terminal
IPFFCMEA_02082	1.63e-39	-	-	-	-	-	-	-	-
IPFFCMEA_02083	1.93e-62	yxlC	-	-	S	-	-	-	Family of unknown function (DUF5345)
IPFFCMEA_02084	2.6e-124	sigY	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_02085	0.0	yxlA	-	-	F	ko:K03457	-	ko00000	Belongs to the purine-cytosine permease (2.A.39) family
IPFFCMEA_02086	3.73e-202	nnrD	4.2.1.136, 5.1.99.6	-	G	ko:K17758,ko:K17759	-	ko00000,ko01000	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IPFFCMEA_02087	0.0	cydD	-	-	V	ko:K16012	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding protein
IPFFCMEA_02088	6.35e-53	cydC	-	-	V	ko:K16013	ko02010,map02010	ko00000,ko00001,ko02000	ATP-binding
IPFFCMEA_02089	1.12e-134	yuaD	-	-	-	-	-	-	-
IPFFCMEA_02090	4.26e-292	gbsB	1.1.1.1	-	C	ko:K11440	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	alcohol dehydrogenase
IPFFCMEA_02091	0.0	gbsA	1.2.1.8	-	C	ko:K00130	ko00260,ko01100,map00260,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPFFCMEA_02092	2.9e-122	yuaC	-	-	K	ko:K22109	-	ko00000,ko03000	Belongs to the GbsR family
IPFFCMEA_02093	5.83e-118	yuaB	-	-	-	-	-	-	-
IPFFCMEA_02094	1.06e-156	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IPFFCMEA_02095	1.07e-300	-	-	-	P	ko:K03498	-	ko00000,ko02000	Potassium
IPFFCMEA_02096	3.31e-52	yubF	-	-	S	-	-	-	yiaA/B two helix domain
IPFFCMEA_02097	1.87e-196	-	-	-	NU	-	-	-	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IPFFCMEA_02098	0.0	yubD	-	-	P	-	-	-	Major Facilitator Superfamily
IPFFCMEA_02099	5.39e-111	cdoA	1.13.11.20	-	S	ko:K00456	ko00270,ko00430,ko01100,map00270,map00430,map01100	ko00000,ko00001,ko01000	Cysteine dioxygenase type I
IPFFCMEA_02101	1.73e-182	uppP	3.6.1.27	-	V	ko:K06153	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IPFFCMEA_02102	1.73e-252	yubA	-	-	S	-	-	-	transporter activity
IPFFCMEA_02103	9.11e-236	yulF	-	-	S	ko:K22230	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IPFFCMEA_02104	0.0	rhaA	2.7.1.5, 5.3.1.14	-	G	ko:K00848,ko:K01813	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Belongs to the rhamnose isomerase family
IPFFCMEA_02105	8.22e-72	rhaM	5.1.3.32	-	G	ko:K03534	-	ko00000,ko01000	Involved in the anomeric conversion of L-rhamnose
IPFFCMEA_02106	0.0	rhaB	2.7.1.5	-	G	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	ko00000,ko00001,ko01000	Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
IPFFCMEA_02107	1.42e-172	yulB	-	-	K	ko:K02530,ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IPFFCMEA_02108	0.0	yuxG	-	-	IQ	-	-	-	Class II Aldolase and Adducin N-terminal domain
IPFFCMEA_02109	2.61e-185	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_02110	2.35e-115	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_02111	0.0	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_02112	2.02e-284	mcpA	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_02113	0.0	mcpB	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_02114	6.15e-181	tgl	2.3.2.13	-	H	ko:K00686	-	ko00000,ko01000	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
IPFFCMEA_02115	5e-48	-	-	-	-	-	-	-	-
IPFFCMEA_02116	0.0	yugT	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPFFCMEA_02117	7.23e-300	yugS	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPFFCMEA_02118	4.8e-150	yugP	-	-	S	ko:K06973	-	ko00000	Zn-dependent protease
IPFFCMEA_02119	2.16e-48	-	-	-	-	-	-	-	-
IPFFCMEA_02120	5.01e-69	mstX	-	-	S	-	-	-	Membrane-integrating protein Mistic
IPFFCMEA_02121	1.69e-231	yugO	-	-	P	ko:K10716	-	ko00000,ko02000	COG1226 Kef-type K transport systems
IPFFCMEA_02122	2.75e-91	yugN	-	-	S	-	-	-	YugN-like family
IPFFCMEA_02124	0.0	pgi	5.3.1.9	-	G	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the GPI family
IPFFCMEA_02125	1.2e-285	yugK	-	-	C	ko:K19955	-	ko00000,ko01000	Dehydrogenase
IPFFCMEA_02126	2.85e-287	yugJ	-	-	C	ko:K19955	-	ko00000,ko01000	oxidoreductases, Fe-dependent alcohol dehydrogenase family
IPFFCMEA_02127	2.21e-46	yuzA	-	-	S	ko:K09779	-	ko00000	Domain of unknown function (DUF378)
IPFFCMEA_02128	5e-83	yugI	-	-	J	ko:K07570,ko:K07571	-	ko00000	RNA binding protein (contains ribosomal protein S1 domain)
IPFFCMEA_02129	5.43e-255	yugH	-	-	E	ko:K10907	-	ko00000,ko01000,ko01007	Aminotransferase
IPFFCMEA_02130	6.74e-112	alaR	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_02131	9.89e-201	yugF	-	-	I	-	-	-	Hydrolase
IPFFCMEA_02132	8.84e-52	yugE	-	-	S	-	-	-	Domain of unknown function (DUF1871)
IPFFCMEA_02133	3.32e-286	patB	4.4.1.8	-	E	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko01000,ko01007	COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IPFFCMEA_02134	4.32e-296	kinB2	2.7.13.3	-	T	ko:K07697	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_02135	8.36e-90	kapB	-	-	G	ko:K06347	ko02020,map02020	ko00000,ko00001	Kinase associated protein B
IPFFCMEA_02136	1.71e-149	kapD	-	-	L	ko:K06348	-	ko00000	the KinA pathway to sporulation
IPFFCMEA_02138	4.61e-244	yuxJ	-	-	EGP	-	-	-	Major facilitator superfamily
IPFFCMEA_02139	0.0	pbpD	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555,ko:K18770	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	Penicillin-binding Protein
IPFFCMEA_02140	1.92e-97	yuxK	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02141	4.19e-113	yufK	-	-	S	-	-	-	Family of unknown function (DUF5366)
IPFFCMEA_02142	0.0	malK	2.7.13.3	-	T	ko:K11614,ko:K11637,ko:K11691	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Signal transduction histidine kinase regulating citrate malate metabolism
IPFFCMEA_02143	1.88e-161	dcuR	-	-	T	ko:K02475,ko:K11615	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG4565 Response regulator of citrate malate metabolism
IPFFCMEA_02144	9e-254	tcsA	-	-	S	ko:K02058,ko:K07335	-	ko00000,ko00002,ko02000	ABC-type transport system, periplasmic component surface lipoprotein
IPFFCMEA_02145	0.0	yufO	3.6.3.17	-	S	ko:K02056	-	ko00000,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_02146	1.29e-236	yufP	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IPFFCMEA_02147	1.15e-213	yufQ	-	-	S	ko:K02057	-	ko00000,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IPFFCMEA_02148	9.73e-310	malP	-	-	C	ko:K11616	ko02020,map02020	ko00000,ko00001	COG3493 Na citrate symporter
IPFFCMEA_02149	1.42e-21	-	-	-	-	-	-	-	-
IPFFCMEA_02150	0.0	mrpA	-	-	CP	ko:K05565	-	ko00000,ko02000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IPFFCMEA_02151	7.66e-91	mrpB	-	-	P	ko:K05566	-	ko00000,ko02000	Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPFFCMEA_02152	3.48e-66	mrpC	-	-	P	ko:K05567	-	ko00000,ko02000	Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPFFCMEA_02153	0.0	mrpD	-	-	CP	ko:K05568	-	ko00000,ko02000	Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPFFCMEA_02154	2.12e-102	mrpE	-	-	P	ko:K05569	-	ko00000,ko02000	Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPFFCMEA_02155	2.23e-51	mrpF	-	-	P	ko:K05570	-	ko00000,ko02000	Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IPFFCMEA_02156	8.49e-79	mrpG	-	-	P	ko:K05571	-	ko00000,ko02000	COG1320 Multisubunit Na H antiporter, MnhG subunit
IPFFCMEA_02157	9.49e-84	yuxO	-	-	Q	-	-	-	protein, possibly involved in aromatic compounds catabolism
IPFFCMEA_02158	2.06e-150	comA	-	-	K	ko:K07691	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_02159	0.0	comP	2.7.13.3	-	T	ko:K07680	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_02161	3.33e-168	comQ	-	-	H	ko:K02251	ko02024,map02024	ko00000,ko00001,ko02044	Belongs to the FPP GGPP synthase family
IPFFCMEA_02162	6.29e-10	-	-	-	S	-	-	-	DegQ (SacQ) family
IPFFCMEA_02164	8.73e-09	yuzC	-	-	-	-	-	-	-
IPFFCMEA_02165	6.88e-297	yuxH	-	-	T	-	-	-	signal transduction protein containing EAL and modified HD-GYP domains
IPFFCMEA_02166	0.0	pncB	6.3.4.21	-	H	ko:K00763	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IPFFCMEA_02167	3.82e-133	pncA	-	-	Q	ko:K16788	-	ko00000,ko02000	COG1335 Amidases related to nicotinamidase
IPFFCMEA_02168	8.92e-87	-	-	-	S	-	-	-	Protein of unknown function (DUF1694)
IPFFCMEA_02169	1.63e-52	yueH	-	-	S	-	-	-	YueH-like protein
IPFFCMEA_02170	6.9e-41	yueG	-	-	S	ko:K06299	-	ko00000	Spore germination protein gerPA/gerPF
IPFFCMEA_02171	1.35e-244	yueF	-	-	S	-	-	-	transporter activity
IPFFCMEA_02172	6.59e-92	-	-	-	S	-	-	-	Protein of unknown function (DUF2283)
IPFFCMEA_02173	1.19e-32	-	-	-	S	-	-	-	Protein of unknown function (DUF2642)
IPFFCMEA_02174	3.85e-125	yueE	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IPFFCMEA_02175	6.83e-168	yueD	1.1.1.320	-	IQ	ko:K16216	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_02176	1.78e-96	yueC	-	-	S	-	-	-	Family of unknown function (DUF5383)
IPFFCMEA_02177	0.0	yueB	-	-	S	-	-	-	type VII secretion protein EsaA
IPFFCMEA_02178	0.0	essC	-	-	D	ko:K03466	-	ko00000,ko03036	COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IPFFCMEA_02179	1.93e-267	essB	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukC
IPFFCMEA_02180	1.93e-54	yukD	-	-	S	-	-	-	WXG100 protein secretion system (Wss), protein YukD
IPFFCMEA_02181	3.93e-60	yukE	-	-	S	-	-	-	Belongs to the WXG100 family
IPFFCMEA_02182	2.96e-292	yukF	-	-	QT	-	-	-	Transcriptional regulator
IPFFCMEA_02183	4.02e-262	ald	1.4.1.1	-	E	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	ko00000,ko00001,ko01000	Belongs to the AlaDH PNT family
IPFFCMEA_02184	1.2e-168	yukJ	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2278)
IPFFCMEA_02185	2.02e-47	mbtH	-	-	S	ko:K05375	ko00261,ko01130,map00261,map01130	ko00000,ko00001,ko00002	MbtH-like protein
IPFFCMEA_02186	0.0	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_02187	1.98e-18	dhbF	-	-	Q	ko:K04780	ko01053,map01053	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_02188	2.59e-227	dhbB	3.3.2.1, 6.3.2.14	-	Q	ko:K01252	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	Isochorismatase family
IPFFCMEA_02189	0.0	entE	2.7.7.58, 6.3.2.14	-	Q	ko:K02363,ko:K04783	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000,ko01008	2,3-dihydroxybenzoate-AMP ligase
IPFFCMEA_02190	5.78e-288	dhbC	5.4.4.2	-	HQ	ko:K02361	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Isochorismate synthase
IPFFCMEA_02191	5.83e-178	dhbA	1.3.1.28	-	IQ	ko:K00216	ko01053,ko01110,ko01130,map01053,map01110,map01130	ko00000,ko00001,ko01000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_02192	1.27e-212	eSD	-	-	S	ko:K07017	-	ko00000	Putative esterase
IPFFCMEA_02193	2.36e-157	yuiH	-	-	S	-	-	-	Oxidoreductase molybdopterin binding domain
IPFFCMEA_02194	8.33e-125	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Biotin biosynthesis protein
IPFFCMEA_02195	3.65e-279	yuiF	-	-	S	ko:K07084	-	ko00000,ko02000	antiporter
IPFFCMEA_02196	0.0	pepA	3.4.11.1	-	E	ko:K01255	ko00480,ko01100,map00480,map01100	ko00000,ko00001,ko01000,ko01002	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPFFCMEA_02197	8.63e-102	yuiD	-	-	S	ko:K09775	-	ko00000	protein conserved in bacteria
IPFFCMEA_02198	2.69e-148	yuiC	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02199	1.97e-46	yuiB	-	-	S	-	-	-	Putative membrane protein
IPFFCMEA_02200	1.39e-299	yumB	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IPFFCMEA_02201	1.92e-239	yumC	1.18.1.2, 1.19.1.1	-	C	ko:K21567	-	ko00000,ko01000	reductase
IPFFCMEA_02203	5.26e-234	guaC	1.7.1.7	-	F	ko:K00364	ko00230,map00230	ko00000,ko00001,ko01000	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IPFFCMEA_02204	1.36e-123	paiB	-	-	K	ko:K07734	-	ko00000,ko03000	Putative FMN-binding domain
IPFFCMEA_02205	6.81e-83	erpA	-	-	S	ko:K13628	-	ko00000,ko03016	Belongs to the HesB IscA family
IPFFCMEA_02206	3.9e-208	dapF	5.1.1.7	-	E	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPFFCMEA_02207	6.25e-270	yutK	-	-	F	ko:K03317	-	ko00000	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPFFCMEA_02208	5.2e-186	pdxK	2.7.1.35, 2.7.1.49, 2.7.4.7	-	H	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IPFFCMEA_02209	4.68e-192	ywdF	-	-	S	-	-	-	Glycosyltransferase like family 2
IPFFCMEA_02210	2.32e-166	ung	3.2.2.27	-	L	ko:K03648	ko03410,ko05340,map03410,map05340	ko00000,ko00001,ko01000,ko03400	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IPFFCMEA_02211	0.0	ywdH	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPFFCMEA_02212	1.26e-62	ywdI	-	-	S	-	-	-	Family of unknown function (DUF5327)
IPFFCMEA_02213	1.86e-303	ywdJ	-	-	F	-	-	-	Xanthine uracil
IPFFCMEA_02214	1.59e-78	ywdK	-	-	S	-	-	-	small membrane protein
IPFFCMEA_02215	3.7e-106	gerQ	-	-	S	ko:K06305	-	ko00000	Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IPFFCMEA_02216	8.08e-187	spsA	-	-	M	-	-	-	Spore Coat
IPFFCMEA_02217	0.0	spsB	-	-	M	-	-	-	Capsule polysaccharide biosynthesis protein
IPFFCMEA_02218	3.06e-283	spsC	2.6.1.102	-	E	ko:K13010	ko00520,map00520	ko00000,ko00001,ko01000,ko01005,ko01007	Belongs to the DegT DnrJ EryC1 family
IPFFCMEA_02219	2.01e-208	spsD	2.3.1.210	-	K	ko:K16704	-	ko00000,ko01000	Spore Coat
IPFFCMEA_02220	7.93e-271	pseI	2.5.1.56, 2.5.1.97	-	M	ko:K01654,ko:K15898	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	acid synthase
IPFFCMEA_02221	2.47e-164	spsF	-	-	M	ko:K07257	-	ko00000	Spore Coat
IPFFCMEA_02222	4.71e-239	spsG	-	-	M	-	-	-	Spore Coat
IPFFCMEA_02223	6.13e-177	spsI	2.7.7.24	-	M	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IPFFCMEA_02224	9.08e-234	spsJ	4.2.1.46	-	M	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IPFFCMEA_02225	2.34e-204	rfbD	1.1.1.133	-	M	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IPFFCMEA_02226	1.52e-112	spsL	5.1.3.13	-	M	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	ko00000,ko00001,ko00002,ko01000	Spore Coat
IPFFCMEA_02227	3.7e-101	-	-	-	-	-	-	-	-
IPFFCMEA_02228	5.19e-311	rocG	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IPFFCMEA_02229	0.0	rocA	1.2.1.88	-	C	ko:K00294	ko00250,ko00330,ko01100,map00250,map00330,map01100	ko00000,ko00001,ko01000	Belongs to the aldehyde dehydrogenase family. RocA subfamily
IPFFCMEA_02230	0.0	rocB	-	-	E	-	-	-	arginine degradation protein
IPFFCMEA_02231	0.0	rocC	-	-	E	ko:K02205,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPFFCMEA_02232	3.81e-275	ywfA	-	-	EGP	-	-	-	-transporter
IPFFCMEA_02233	1.39e-37	-	-	-	L	-	-	-	DnaD domain protein
IPFFCMEA_02235	0.000533	-	-	-	K	ko:K07075,ko:K15773	-	ko00000,ko02048,ko03000	sequence-specific DNA binding
IPFFCMEA_02236	1.47e-67	ypuA	-	-	S	-	-	-	Protein of unknown function (DUF1002)
IPFFCMEA_02247	2.17e-10	-	-	-	-	-	-	-	-
IPFFCMEA_02248	4.66e-68	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IPFFCMEA_02249	1.7e-177	-	-	-	M	-	-	-	Psort location Cellwall, score
IPFFCMEA_02256	4.77e-16	-	-	-	S	-	-	-	YolD-like protein
IPFFCMEA_02258	1.48e-34	-	-	-	-	-	-	-	-
IPFFCMEA_02259	2.37e-47	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
IPFFCMEA_02261	8.48e-171	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_02265	4.71e-55	-	-	-	L	ko:K07491	-	ko00000	Transposase IS200 like
IPFFCMEA_02266	6.41e-118	ywjG	-	-	S	-	-	-	Domain of unknown function (DUF2529)
IPFFCMEA_02267	1.07e-81	spo0F	-	-	T	ko:K02490	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG0784 FOG CheY-like receiver
IPFFCMEA_02268	7.82e-204	fbaA	4.1.2.13, 4.1.2.29	-	G	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Aldolase
IPFFCMEA_02269	5.69e-147	tal	2.2.1.2	-	G	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPFFCMEA_02271	2.26e-303	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPFFCMEA_02272	2.03e-224	glpX	3.1.3.11	-	G	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	fructose-1,6-bisphosphatase
IPFFCMEA_02273	5.53e-303	rho	-	-	K	ko:K03628	ko03018,map03018	ko00000,ko00001,ko03019,ko03021	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPFFCMEA_02274	7e-45	rpmE	-	-	J	ko:K02909	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds the 23S rRNA
IPFFCMEA_02275	9.96e-135	tdk	2.7.1.21	-	F	ko:K00857	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	thymidine kinase
IPFFCMEA_02276	0.0	ykwA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IPFFCMEA_02277	3.24e-204	ywkB	-	-	S	ko:K07088	-	ko00000	Membrane transport protein
IPFFCMEA_02278	2.45e-116	racA	-	-	K	ko:K11686	-	ko00000,ko03036	Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IPFFCMEA_02279	1.19e-89	ywkD	-	-	E	ko:K08234	-	ko00000	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPFFCMEA_02280	9.95e-245	prfA	-	-	J	ko:K02835	-	ko00000,ko03012	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPFFCMEA_02281	5.96e-205	prmC	2.1.1.297	-	J	ko:K02493	-	ko00000,ko01000,ko03012	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IPFFCMEA_02283	9.69e-74	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IPFFCMEA_02284	2.29e-152	spoIIR	-	-	S	ko:K06387	-	ko00000	stage II sporulation protein R
IPFFCMEA_02285	2.55e-100	ywlB	-	-	E	-	-	-	Belongs to the acetyltransferase family. ArgA subfamily
IPFFCMEA_02286	2.36e-247	ywlC	2.7.7.87	-	J	ko:K07566	-	ko00000,ko01000,ko03009,ko03016	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IPFFCMEA_02287	6.48e-117	mntP	-	-	P	-	-	-	Probably functions as a manganese efflux pump
IPFFCMEA_02288	9.54e-102	ywlE	3.1.3.48, 3.9.1.2	-	T	ko:K01104,ko:K20201	-	ko00000,ko01000	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IPFFCMEA_02289	9.57e-106	rpiB	5.3.1.6	-	G	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Ribose 5-phosphate isomerase
IPFFCMEA_02290	2.49e-123	ywlG	-	-	S	-	-	-	Belongs to the UPF0340 family
IPFFCMEA_02291	4.36e-303	glyA	2.1.2.1	-	E	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPFFCMEA_02292	5.5e-148	upp	2.4.2.9	-	F	ko:K00761	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko01000	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IPFFCMEA_02293	1.91e-81	atpI	-	-	S	ko:K02116	-	ko00000,ko00194	ATP synthase
IPFFCMEA_02294	6.06e-167	atpB	-	-	C	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko03110	it plays a direct role in the translocation of protons across the membrane
IPFFCMEA_02295	3.01e-36	atpE	-	-	C	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPFFCMEA_02296	2.62e-79	atpF	-	-	C	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPFFCMEA_02297	5.36e-114	atpH	-	-	C	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPFFCMEA_02298	0.0	atpA	3.6.3.14	-	C	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPFFCMEA_02299	1.28e-194	atpG	-	-	C	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPFFCMEA_02300	0.0	atpD	3.6.3.14	-	C	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194,ko01000	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPFFCMEA_02301	2.44e-75	atpC	-	-	C	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	ko00000,ko00001,ko00002,ko00194	Produces ATP from ADP in the presence of a proton gradient across the membrane
IPFFCMEA_02302	2.92e-113	ywmA	-	-	-	-	-	-	-
IPFFCMEA_02303	4.54e-45	ywzB	-	-	S	-	-	-	membrane
IPFFCMEA_02304	6.59e-172	ywmB	-	-	S	-	-	-	TATA-box binding
IPFFCMEA_02305	4.96e-306	murA	2.5.1.7	-	M	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPFFCMEA_02306	3.05e-237	spoIID	-	-	D	ko:K06381	-	ko00000	Stage II sporulation protein D
IPFFCMEA_02307	5.21e-155	ywmC	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IPFFCMEA_02308	3.4e-154	ywmD	-	-	S	ko:K07114	-	ko00000,ko02000	protein containing a von Willebrand factor type A (vWA) domain
IPFFCMEA_02310	9.06e-187	fdhD	-	-	C	ko:K02379	-	ko00000	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IPFFCMEA_02311	1.08e-245	moaA	4.1.99.22	-	H	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IPFFCMEA_02312	6.22e-129	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_02313	8.55e-110	ywmF	-	-	S	-	-	-	Peptidase M50
IPFFCMEA_02314	2.15e-19	csbD	-	-	K	-	-	-	CsbD-like
IPFFCMEA_02315	0.000282	-	-	-	E	ko:K11959	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Receptor family ligand binding region
IPFFCMEA_02316	6.75e-67	ureA	3.5.1.5	-	E	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease gamma subunit family
IPFFCMEA_02317	1.12e-83	ureB	3.5.1.5	-	E	ko:K01429	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	ko00000,ko00001,ko01000	Belongs to the urease beta subunit family
IPFFCMEA_02318	0.0	ureC	3.5.1.5	-	E	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IPFFCMEA_02319	4.58e-85	ywnA	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_02320	6.73e-19	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IPFFCMEA_02321	1.42e-112	ywnB	-	-	S	ko:K07118	-	ko00000	NAD(P)H-binding
IPFFCMEA_02322	1.06e-78	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IPFFCMEA_02323	1.28e-179	mta	-	-	K	ko:K21743	-	ko00000,ko03000	transcriptional
IPFFCMEA_02324	0.0	ywnE	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPFFCMEA_02325	1.05e-91	ywnF	-	-	S	-	-	-	Family of unknown function (DUF5392)
IPFFCMEA_02326	6.7e-234	-	-	-	M	-	-	-	NeuB family
IPFFCMEA_02327	5.63e-17	ywnC	-	-	S	-	-	-	Family of unknown function (DUF5362)
IPFFCMEA_02328	2.12e-114	ywnH	2.3.1.183	-	M	ko:K03823	ko00440,ko01130,map00440,map01130	ko00000,ko00001,ko01000	COG1247 Sortase and related acyltransferases
IPFFCMEA_02329	1.85e-161	spoIIQ	-	-	M	ko:K06386	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IPFFCMEA_02330	9.05e-93	ywnJ	-	-	S	-	-	-	VanZ like family
IPFFCMEA_02331	6.02e-135	bcrC	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	COG0671 Membrane-associated phospholipid phosphatase
IPFFCMEA_02332	4.51e-77	nrgB	-	-	K	ko:K04751	ko02020,map02020	ko00000,ko00001	Belongs to the P(II) protein family
IPFFCMEA_02333	3.76e-287	nrgA	-	-	P	ko:K03320	-	ko00000,ko02000	Ammonium transporter
IPFFCMEA_02334	7.16e-101	-	-	-	-	-	-	-	-
IPFFCMEA_02335	1.04e-133	yjgF	-	-	Q	-	-	-	Isochorismatase family
IPFFCMEA_02336	8.92e-306	ywoD	-	-	EGP	-	-	-	Major facilitator superfamily
IPFFCMEA_02337	0.0	-	-	-	FH	ko:K03457,ko:K10975	-	ko00000,ko02000	COG1953 Cytosine uracil thiamine allantoin permeases
IPFFCMEA_02338	3.25e-309	ywoF	-	-	P	-	-	-	Right handed beta helix region
IPFFCMEA_02339	1.37e-269	ywoG	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_02340	8.45e-92	-	-	-	K	-	-	-	COG1846 Transcriptional regulators
IPFFCMEA_02341	4.88e-59	spoIIID	-	-	K	ko:K06283	-	ko00000,ko03000	Stage III sporulation protein D
IPFFCMEA_02342	1.75e-231	mbl	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein
IPFFCMEA_02343	9.37e-168	flhO	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IPFFCMEA_02344	1.17e-181	flhP	-	-	N	ko:K02392	ko02040,map02040	ko00000,ko00001,ko02035	flagellar basal body
IPFFCMEA_02345	1.5e-254	rapD	-	-	S	ko:K06362	-	ko00000,ko01000	aspartate phosphatase
IPFFCMEA_02346	6.89e-107	fabZ	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IPFFCMEA_02347	7.66e-76	mscL	-	-	M	ko:K03282	-	ko00000,ko02000	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IPFFCMEA_02348	4.66e-186	ywpD	-	-	T	-	-	-	Histidine kinase
IPFFCMEA_02349	3.81e-67	srtA	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	Sortase family
IPFFCMEA_02350	3.59e-88	ywpF	-	-	S	-	-	-	YwpF-like protein
IPFFCMEA_02351	2.79e-40	ywpG	-	-	-	-	-	-	-
IPFFCMEA_02352	4.23e-76	ssbB	-	-	L	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	ko00000,ko00001,ko03029,ko03032,ko03400	Single-stranded DNA-binding protein
IPFFCMEA_02353	4.82e-180	glcR	-	-	K	ko:K22103	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IPFFCMEA_02354	3.57e-200	ywpJ	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IPFFCMEA_02355	0.0	ywqA	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IPFFCMEA_02356	0.0	ywqB	-	-	S	-	-	-	SWIM zinc finger
IPFFCMEA_02357	3.6e-25	-	-	-	-	-	-	-	-
IPFFCMEA_02358	5.33e-163	ywqC	-	-	M	ko:K19420	-	ko00000	biosynthesis protein
IPFFCMEA_02359	1.06e-152	ywqD	2.7.10.2	-	D	ko:K00903	-	ko00000,ko01000,ko01001	COG0489 ATPases involved in chromosome partitioning
IPFFCMEA_02360	5.03e-180	ywqE	3.1.3.48	-	GM	ko:K01104	-	ko00000,ko01000	COG4464 Capsular polysaccharide biosynthesis protein
IPFFCMEA_02361	6.34e-311	ywqF	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPFFCMEA_02362	9.48e-193	ywqG	-	-	S	-	-	-	Domain of unknown function (DUF1963)
IPFFCMEA_02364	8.84e-52	ywqI	-	-	S	-	-	-	Family of unknown function (DUF5344)
IPFFCMEA_02365	3.15e-265	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
IPFFCMEA_02366	2.5e-26	-	-	-	-	-	-	-	-
IPFFCMEA_02367	1.3e-23	-	-	-	-	-	-	-	-
IPFFCMEA_02368	4.93e-95	ywqJ	-	-	S	-	-	-	Pre-toxin TG
IPFFCMEA_02369	9.77e-48	-	-	-	S	ko:K11904,ko:K21493	ko03070,map03070	ko00000,ko00001,ko00002,ko01000,ko02044,ko02048	protein secretion by the type VII secretion system
IPFFCMEA_02371	2.88e-147	nfi	3.1.21.7	-	L	ko:K05982	-	ko00000,ko01000,ko03400	DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IPFFCMEA_02372	4.73e-209	-	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_02373	1.44e-127	ywqN	-	-	S	-	-	-	NAD(P)H-dependent
IPFFCMEA_02375	1.01e-112	ywrA	-	-	P	ko:K07240	-	ko00000,ko02000	COG2059 Chromate transport protein ChrA
IPFFCMEA_02376	6.44e-132	ywrB	-	-	P	ko:K07240	-	ko00000,ko02000	Chromate transporter
IPFFCMEA_02377	2.79e-107	ywrC	-	-	K	ko:K03719	-	ko00000,ko03000,ko03036	Transcriptional regulator
IPFFCMEA_02378	0.0	ywrD	2.3.2.2, 3.4.19.13	-	E	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	ko00000,ko00001,ko01000,ko01002	gamma-glutamyltransferase
IPFFCMEA_02379	2.78e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4181)
IPFFCMEA_02380	5.08e-142	ywrF	-	-	S	-	-	-	COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IPFFCMEA_02381	1e-17	-	-	-	-	-	-	-	-
IPFFCMEA_02382	8.48e-265	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IPFFCMEA_02383	3.02e-44	cotB	-	-	-	ko:K06325	-	ko00000	-
IPFFCMEA_02384	1.06e-162	ywrJ	-	-	-	-	-	-	-
IPFFCMEA_02385	8.01e-263	ywrK	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPFFCMEA_02386	3.36e-218	alsR	-	-	K	-	-	-	LysR substrate binding domain
IPFFCMEA_02387	0.0	alsS	2.2.1.6	-	EH	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TPP enzyme family
IPFFCMEA_02388	1.51e-186	budA	4.1.1.5	-	H	ko:K01575	ko00650,ko00660,map00650,map00660	ko00000,ko00001,ko01000	Alpha-acetolactate decarboxylase
IPFFCMEA_02389	1.24e-125	ywrO	-	-	S	-	-	-	NADPH-quinone reductase (modulator of drug activity B)
IPFFCMEA_02390	3.75e-63	ywsA	-	-	S	-	-	-	Protein of unknown function (DUF3892)
IPFFCMEA_02391	1.14e-118	batE	-	-	T	-	-	-	Sh3 type 3 domain protein
IPFFCMEA_02392	2.59e-203	rbsB	-	-	G	ko:K10439	ko02010,ko02030,map02010,map02030	ko00000,ko00001,ko00002,ko02000	COG1879 ABC-type sugar transport system, periplasmic component
IPFFCMEA_02393	3.35e-203	rbsC	-	-	G	ko:K10440	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family
IPFFCMEA_02394	0.0	rbsA	3.6.3.17	-	G	ko:K10441	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IPFFCMEA_02395	3.12e-82	rbsD	5.4.99.62	-	G	ko:K06726	ko02010,map02010	ko00000,ko00001,ko01000	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IPFFCMEA_02396	8.06e-201	rbsK	2.7.1.15	-	H	ko:K00852	ko00030,map00030	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPFFCMEA_02397	5.85e-225	rbsR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IPFFCMEA_02398	2.21e-233	fni	5.3.3.2	-	C	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IPFFCMEA_02399	7.8e-262	rpsA	-	-	J	ko:K02945	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Ribosomal protein S1
IPFFCMEA_02400	5.8e-146	cmk	2.7.4.25	-	F	ko:K00945	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the cytidylate kinase family. Type 1 subfamily
IPFFCMEA_02401	1.74e-32	-	-	-	S	-	-	-	Family of unknown function (DUF5359)
IPFFCMEA_02402	2.02e-138	ypfA	-	-	M	-	-	-	Flagellar protein YcgR
IPFFCMEA_02403	0.0	ypeB	-	-	H	ko:K06313	-	ko00000	sporulation protein
IPFFCMEA_02404	1.99e-207	sleB	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Spore cortex-lytic enzyme
IPFFCMEA_02405	1.76e-153	prsW	-	-	S	-	-	-	Involved in the degradation of specific anti-sigma factors
IPFFCMEA_02406	2.51e-222	ypdA	1.8.1.9	-	O	ko:K00384	ko00450,map00450	ko00000,ko00001,ko01000	COG0492 Thioredoxin reductase
IPFFCMEA_02407	1.42e-308	gudB	1.4.1.2	-	E	ko:K00260	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	ko00000,ko00001,ko01000	Belongs to the Glu Leu Phe Val dehydrogenases family
IPFFCMEA_02408	5.56e-136	mecB	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IPFFCMEA_02409	4.33e-188	ypbG	-	-	S	ko:K07098	-	ko00000	Calcineurin-like phosphoesterase superfamily domain
IPFFCMEA_02410	4.08e-106	ypbF	-	-	S	-	-	-	Protein of unknown function (DUF2663)
IPFFCMEA_02411	5.04e-148	ypbE	-	-	M	-	-	-	Lysin motif
IPFFCMEA_02412	3.55e-128	ypbD	-	-	S	ko:K07052	-	ko00000	metal-dependent membrane protease
IPFFCMEA_02413	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPFFCMEA_02414	3.14e-255	ypbB	5.1.3.1	-	S	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	protein conserved in bacteria
IPFFCMEA_02415	8.35e-55	fer	-	-	C	ko:K05337	-	ko00000	Ferredoxin
IPFFCMEA_02416	3.07e-122	ribU	-	-	U	-	-	-	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IPFFCMEA_02417	0.0	serA	1.1.1.399, 1.1.1.95	-	E	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPFFCMEA_02418	9.27e-172	aroD	4.2.1.10	-	E	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IPFFCMEA_02419	2.96e-135	rsiX	-	-	-	-	-	-	-
IPFFCMEA_02420	8.11e-17	rsiX	-	-	-	-	-	-	-
IPFFCMEA_02421	1.08e-133	sigX	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_02422	0.0	resE	2.7.13.3	-	T	ko:K07651	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_02423	1.69e-171	resD	-	-	T	ko:K07775	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_02424	1.56e-277	resC	-	-	O	-	-	-	'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IPFFCMEA_02425	0.0	resB	-	-	O	ko:K07399	-	ko00000	COG1333 ResB protein required for cytochrome c biosynthesis
IPFFCMEA_02426	8.71e-128	resA	-	-	CO	-	-	-	Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IPFFCMEA_02427	4.45e-169	rluB	5.4.99.22	-	J	ko:K06178	-	ko00000,ko01000,ko03009	Belongs to the pseudouridine synthase RsuA family
IPFFCMEA_02428	8.62e-114	spmB	-	-	S	ko:K06374	-	ko00000	Spore maturation protein
IPFFCMEA_02429	7.57e-135	spmA	-	-	S	ko:K06373	-	ko00000	Spore maturation protein
IPFFCMEA_02430	1.18e-272	dacB	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IPFFCMEA_02431	2.92e-126	ypuI	-	-	S	-	-	-	Protein of unknown function (DUF3907)
IPFFCMEA_02432	9.54e-134	scpB	-	-	D	ko:K06024	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPFFCMEA_02433	3.82e-167	scpA	-	-	D	ko:K05896	-	ko00000,ko03036	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IPFFCMEA_02434	1.4e-117	ypuF	-	-	S	ko:K09763	-	ko00000	Domain of unknown function (DUF309)
IPFFCMEA_02435	1.12e-83	ribT	-	-	K	ko:K02859	-	ko00000	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_02436	8.41e-107	ribH	2.5.1.78	-	H	ko:K00794	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IPFFCMEA_02437	1.04e-290	ribBA	3.5.4.25, 4.1.99.12	-	H	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IPFFCMEA_02438	2.5e-147	ribE	2.5.1.9	-	H	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Riboflavin synthase
IPFFCMEA_02439	3.42e-259	ribD	1.1.1.193, 3.5.4.26	-	H	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	ko00000,ko00001,ko00002,ko01000	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IPFFCMEA_02440	5.98e-72	ypuD	-	-	-	-	-	-	-
IPFFCMEA_02441	3.63e-120	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPFFCMEA_02443	7.41e-45	ypzJ	-	-	S	ko:K07069	-	ko00000	nucleic-acid-binding protein containing a Zn-ribbon domain
IPFFCMEA_02445	5.68e-58	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPFFCMEA_02447	3.82e-37	-	-	-	-	-	-	-	-
IPFFCMEA_02448	1.22e-29	-	-	-	L	ko:K01173	ko04210,map04210	ko00000,ko00001,ko03029	DNA/RNA non-specific endonuclease
IPFFCMEA_02450	8.16e-77	-	-	-	O	-	-	-	Papain family cysteine protease
IPFFCMEA_02451	1.73e-13	-	-	-	-	-	-	-	-
IPFFCMEA_02453	6.48e-288	brnQ	-	-	E	ko:K03311	-	ko00000	Component of the transport system for branched-chain amino acids
IPFFCMEA_02454	1.97e-66	azlD	-	-	E	-	-	-	Branched-chain amino acid transport protein (AzlD)
IPFFCMEA_02455	9.34e-176	azlC	-	-	E	-	-	-	AzlC protein
IPFFCMEA_02456	4.82e-103	bkdR	-	-	K	-	-	-	helix_turn_helix ASNC type
IPFFCMEA_02457	2.76e-55	yrdF	-	-	K	ko:K03623	-	ko00000	ribonuclease inhibitor
IPFFCMEA_02458	1.74e-131	yrdC	-	-	Q	-	-	-	Isochorismatase family
IPFFCMEA_02459	3.24e-75	-	-	-	S	-	-	-	Protein of unknown function (DUF2568)
IPFFCMEA_02460	2.01e-118	yrdA	-	-	S	-	-	-	DinB family
IPFFCMEA_02461	3.9e-210	aadK	-	-	G	ko:K05593	-	ko00000,ko01000,ko01504	Streptomycin adenylyltransferase
IPFFCMEA_02462	2.45e-245	npd	1.13.12.16	-	S	ko:K00459	ko00910,map00910	ko00000,ko00001,ko01000	COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IPFFCMEA_02463	9.78e-188	murI	5.1.1.3	-	M	ko:K01776	ko00471,ko01100,map00471,map01100	ko00000,ko00001,ko01000,ko01011	Provides the (R)-glutamate required for cell wall biosynthesis
IPFFCMEA_02464	2.39e-162	yrpD	-	-	S	-	-	-	Domain of unknown function, YrpD
IPFFCMEA_02466	4.22e-164	zinT	-	-	S	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
IPFFCMEA_02467	2.5e-121	-	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_02468	4.9e-239	yrpG	-	-	C	-	-	-	Aldo/keto reductase family
IPFFCMEA_02469	2.2e-193	csn	3.2.1.132	-	M	ko:K01233	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IPFFCMEA_02470	6.15e-57	yraL	-	-	S	-	-	-	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_02471	1.19e-191	-	-	-	S	-	-	-	Alpha beta hydrolase
IPFFCMEA_02472	6.61e-80	-	-	-	T	-	-	-	sh3 domain protein
IPFFCMEA_02473	2.92e-81	-	-	-	T	-	-	-	sh3 domain protein
IPFFCMEA_02474	6.62e-87	-	-	-	E	-	-	-	Glyoxalase-like domain
IPFFCMEA_02475	4.19e-50	yraG	-	-	-	ko:K06440	-	ko00000	-
IPFFCMEA_02476	9.61e-84	yraF	-	-	M	-	-	-	Spore coat protein
IPFFCMEA_02477	9.1e-284	adhB	1.1.1.1, 1.1.1.284, 1.2.1.46	-	E	ko:K00121,ko:K00148	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	ko00000,ko00001,ko01000	COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IPFFCMEA_02478	6.11e-36	yraE	-	-	-	ko:K06440	-	ko00000	-
IPFFCMEA_02479	7.23e-66	yraD	-	-	M	ko:K06439	-	ko00000	Spore coat protein
IPFFCMEA_02480	1.83e-67	adhR	-	-	K	ko:K21745	-	ko00000,ko03000	helix_turn_helix, mercury resistance
IPFFCMEA_02481	1.76e-39	yphJ	4.1.1.44	-	S	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	ko00000,ko00001,ko01000	peroxiredoxin activity
IPFFCMEA_02482	4.81e-253	adhA	-	-	C	ko:K13979	-	ko00000,ko01000	alcohol dehydrogenase
IPFFCMEA_02483	1.58e-116	yfkM	3.5.1.124	-	S	ko:K05520	-	ko00000,ko01000,ko01002	protease
IPFFCMEA_02484	0.0	sacC	3.2.1.80	-	G	ko:K03332	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 32 family
IPFFCMEA_02485	1.39e-192	levG	-	-	G	ko:K02771,ko:K02796	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
IPFFCMEA_02486	1.44e-166	levF	-	-	G	ko:K02746,ko:K02795,ko:K11196	ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko02000	COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
IPFFCMEA_02487	4.41e-106	ptnA	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11195	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system mannose fructose sorbose family
IPFFCMEA_02488	4.41e-96	levD	2.7.1.191, 2.7.1.202	-	G	ko:K02793,ko:K02794,ko:K11194	ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	PTS system fructose IIA component
IPFFCMEA_02489	0.0	levR	-	-	K	-	-	-	PTS system fructose IIA component
IPFFCMEA_02490	0.0	aapA	-	-	E	ko:K03293,ko:K11737	-	ko00000,ko02000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_02491	5.63e-137	yrhP	-	-	E	-	-	-	LysE type translocator
IPFFCMEA_02492	3.41e-193	yrhO	-	-	K	-	-	-	Archaeal transcriptional regulator TrmB
IPFFCMEA_02493	2.35e-112	sigV	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_02494	3.51e-191	rsiV	-	-	S	-	-	-	Protein of unknown function (DUF3298)
IPFFCMEA_02495	2.18e-84	oatA	-	-	I	-	-	-	Acyltransferase family
IPFFCMEA_02496	0.0	oatA	-	-	I	-	-	-	Acyltransferase family
IPFFCMEA_02497	2.58e-58	yrhK	-	-	S	-	-	-	YrhK-like protein
IPFFCMEA_02498	0.0	yrhJ	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IPFFCMEA_02499	2.26e-135	-	-	-	K	ko:K22106	-	ko00000,ko03000	Tetracycline repressor, C-terminal all-alpha domain
IPFFCMEA_02500	4.3e-124	yrhH	-	-	Q	-	-	-	methyltransferase
IPFFCMEA_02501	9.39e-08	-	-	-	S	-	-	-	Probable sporulation protein (Bac_small_yrzI)
IPFFCMEA_02502	1.13e-182	yrhG	-	-	P	ko:K21993	-	ko00000,ko02000	Formate nitrite
IPFFCMEA_02504	4.41e-80	yrhF	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IPFFCMEA_02505	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IPFFCMEA_02506	2.46e-102	yrhD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IPFFCMEA_02507	5.71e-48	yrhC	-	-	S	-	-	-	YrhC-like protein
IPFFCMEA_02508	8.55e-269	mccB	4.4.1.1, 4.4.1.2, 4.4.1.8	-	E	ko:K01760,ko:K17217	ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IPFFCMEA_02509	1.66e-216	mccA	2.5.1.134, 2.5.1.47	-	E	ko:K01738,ko:K17216	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Cysteine synthase
IPFFCMEA_02510	3.26e-160	mtnN	3.2.2.9	-	E	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IPFFCMEA_02511	9.86e-153	yrrT	-	-	Q	ko:K17462	ko00270,ko01100,ko01230,map00270,map01100,map01230	ko00000,ko00001,ko00002,ko01000	Could be a S-adenosyl-L-methionine-dependent methyltransferase
IPFFCMEA_02512	4.94e-36	yrzA	-	-	S	-	-	-	Protein of unknown function (DUF2536)
IPFFCMEA_02513	2.02e-102	yrrS	-	-	S	-	-	-	Protein of unknown function (DUF1510)
IPFFCMEA_02514	0.0	pbpI	-	-	M	ko:K21468	-	ko00000,ko01011	Penicillin-binding Protein
IPFFCMEA_02515	1.14e-101	greA	-	-	K	ko:K03624	-	ko00000,ko03021	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IPFFCMEA_02516	4.51e-148	udk	2.7.1.48	-	F	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko01000	Cytidine monophosphokinase
IPFFCMEA_02517	4.62e-313	yrrO	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	COG0826 Collagenase and related proteases
IPFFCMEA_02518	2.57e-221	yrrN	-	-	O	ko:K08303	ko05120,map05120	ko00000,ko00001,ko01000,ko01002	Peptidase U32
IPFFCMEA_02519	6.92e-155	yrrM	2.1.1.104	-	S	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	ko00000,ko00001,ko00002,ko01000	O-methyltransferase
IPFFCMEA_02520	6.17e-241	mltG	-	-	S	ko:K07082	-	ko00000	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IPFFCMEA_02521	2.94e-60	yrzB	-	-	S	-	-	-	Belongs to the UPF0473 family
IPFFCMEA_02522	5.49e-93	yrrK	-	-	L	ko:K07447	-	ko00000,ko01000	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPFFCMEA_02523	2.22e-55	yrzL	-	-	S	-	-	-	Belongs to the UPF0297 family
IPFFCMEA_02524	0.0	alaS	6.1.1.7	-	J	ko:K01872	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPFFCMEA_02525	1.25e-241	yrrI	-	-	S	-	-	-	AI-2E family transporter
IPFFCMEA_02526	2.21e-168	glnQ	-	-	E	ko:K09972,ko:K10041	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPFFCMEA_02527	3.93e-182	glnH	-	-	ET	ko:K09969,ko:K10039	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 3 family
IPFFCMEA_02528	3.27e-15	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_02529	2.25e-57	glnM	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_02530	9.26e-140	glnP	-	-	P	ko:K10040	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_02531	0.0	xylB	2.7.1.17	-	G	ko:K00854	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	xylulose kinase
IPFFCMEA_02532	0.0	xylA	5.3.1.5	-	G	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko01000	Belongs to the xylose isomerase family
IPFFCMEA_02533	6.82e-273	xylR	-	-	GK	-	-	-	ROK family
IPFFCMEA_02534	0.0	xynB	3.2.1.37	GH43	G	ko:K01198	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 43 family
IPFFCMEA_02535	0.0	xynP	-	-	G	ko:K03292	-	ko00000	MFS/sugar transport protein
IPFFCMEA_02536	2.81e-106	-	-	-	E	-	-	-	phosphoribosylanthranilate isomerase activity
IPFFCMEA_02538	2.77e-19	ynaF	-	-	-	-	-	-	-
IPFFCMEA_02539	1.9e-102	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IPFFCMEA_02540	4.84e-09	-	-	-	S	-	-	-	Domain of unknown function (DUF3885)
IPFFCMEA_02541	8.64e-34	-	-	-	K	ko:K07727	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IPFFCMEA_02542	2.38e-11	ywlA	-	-	S	-	-	-	Uncharacterised protein family (UPF0715)
IPFFCMEA_02543	3.24e-93	-	-	-	S	-	-	-	CAAX protease self-immunity
IPFFCMEA_02545	8.3e-126	ynaD	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_02546	2.61e-15	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IPFFCMEA_02547	1.16e-243	cydB	1.10.3.14	-	C	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	Cytochrome d ubiquinol oxidase, subunit II
IPFFCMEA_02548	0.0	cydA	1.10.3.14	-	C	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	ko00000,ko00001,ko00002,ko01000	oxidase, subunit
IPFFCMEA_02549	1.09e-307	cimH	-	-	C	-	-	-	COG3493 Na citrate symporter
IPFFCMEA_02550	0.0	-	-	-	O	-	-	-	Peptidase family M48
IPFFCMEA_02552	1.77e-197	yxkH	-	-	G	-	-	-	Polysaccharide deacetylase
IPFFCMEA_02553	3.44e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_02554	7.85e-210	lrp	-	-	QT	-	-	-	PucR C-terminal helix-turn-helix domain
IPFFCMEA_02555	0.0	aldY	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPFFCMEA_02556	2.29e-188	yxkD	-	-	S	-	-	-	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IPFFCMEA_02557	0.0	yvaQ	-	-	NT	ko:K03406	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko02035	chemotaxis protein
IPFFCMEA_02558	3.85e-72	yvaP	-	-	K	-	-	-	transcriptional
IPFFCMEA_02559	9.82e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	Cro/C1-type HTH DNA-binding domain
IPFFCMEA_02560	6.83e-92	yvaO	-	-	K	ko:K22299	-	ko00000,ko03000	transcriptional
IPFFCMEA_02561	4.9e-48	yvzC	-	-	K	-	-	-	transcriptional
IPFFCMEA_02562	2.84e-194	yvaM	1.11.1.10	-	S	ko:K00433	-	ko00000,ko01000	Serine aminopeptidase, S33
IPFFCMEA_02563	1.87e-35	secG	-	-	U	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit SecG
IPFFCMEA_02564	3.43e-183	est	3.1.1.1	-	S	ko:K03928	-	ko00000,ko01000	Carboxylesterase
IPFFCMEA_02565	0.0	rnr	-	-	K	ko:K12573	ko03018,map03018	ko00000,ko00001,ko01000,ko03016,ko03019	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IPFFCMEA_02566	2.4e-107	smpB	-	-	O	ko:K03664	-	ko00000	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPFFCMEA_02568	2.09e-81	-	-	-	S	-	-	-	Phage integrase family
IPFFCMEA_02569	4.26e-43	-	-	-	S	-	-	-	Phage integrase family
IPFFCMEA_02570	3.21e-78	-	-	-	-	-	-	-	-
IPFFCMEA_02572	9.99e-59	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_02573	2.6e-09	-	-	-	T	ko:K21405	-	ko00000,ko03000	PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
IPFFCMEA_02576	1.81e-114	-	-	-	L	-	-	-	Conserved phage C-terminus (Phg_2220_C)
IPFFCMEA_02577	1.04e-21	-	-	-	L	ko:K02315	-	ko00000,ko03032	IstB-like ATP binding protein
IPFFCMEA_02578	1.76e-10	-	-	-	-	-	-	-	-
IPFFCMEA_02579	1.13e-53	-	-	-	S	-	-	-	COG NOG14552 non supervised orthologous group
IPFFCMEA_02581	1.5e-183	spo0M	-	-	S	ko:K06377	-	ko00000	COG4326 Sporulation control protein
IPFFCMEA_02582	1.58e-36	-	-	-	-	-	-	-	-
IPFFCMEA_02583	5.27e-168	ygaJ	3.4.13.21	-	E	ko:K05995	-	ko00000,ko01000,ko01002	Belongs to the peptidase S51 family
IPFFCMEA_02584	0.0	thiC	4.1.99.17	-	H	ko:K03147	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IPFFCMEA_02586	0.0	katA	1.11.1.6	-	P	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	ko00000,ko00001,ko00002,ko01000	serves to protect cells from the toxic effects of hydrogen peroxide
IPFFCMEA_02587	7.4e-178	ssuB	-	-	P	ko:K15555	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IPFFCMEA_02588	2.79e-213	ssuA	-	-	M	ko:K15553	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	Sulfonate ABC transporter
IPFFCMEA_02589	4.62e-187	ssuC	-	-	P	ko:K15554	ko00920,ko02010,map00920,map02010	ko00000,ko00001,ko00002,ko02000	COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IPFFCMEA_02590	8.96e-274	ssuD	1.14.14.28, 1.14.14.5	-	C	ko:K04091,ko:K20938	ko00920,map00920	ko00000,ko00001,ko01000	Catalyzes the desulfonation of aliphatic sulfonates
IPFFCMEA_02593	1.96e-54	rpsN	-	-	J	ko:K02954	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPFFCMEA_02594	6.32e-99	ygaO	-	-	-	-	-	-	-
IPFFCMEA_02595	1.48e-39	-	-	-	K	ko:K07729	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_02597	1.07e-144	yhzB	-	-	S	-	-	-	B3/4 domain
IPFFCMEA_02598	1.7e-283	queG	1.17.99.6	-	C	ko:K18979	-	ko00000,ko01000,ko03016	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IPFFCMEA_02599	9.27e-224	yhbB	-	-	S	-	-	-	Putative amidase domain
IPFFCMEA_02600	1.08e-111	cspR	2.1.1.207	-	J	ko:K03216	-	ko00000,ko01000,ko03016	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IPFFCMEA_02601	3.97e-142	yhbD	-	-	K	-	-	-	Protein of unknown function (DUF4004)
IPFFCMEA_02602	1.53e-94	yhbE	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IPFFCMEA_02603	3.01e-105	yhbF	-	-	M	-	-	-	COG1664 Integral membrane protein CcmA involved in cell shape determination
IPFFCMEA_02604	0.0	prkA	-	-	T	ko:K07180	-	ko00000	Ser protein kinase
IPFFCMEA_02605	1.21e-286	yhbH	-	-	S	ko:K09786	-	ko00000	Belongs to the UPF0229 family
IPFFCMEA_02606	1.29e-101	yhbI	-	-	K	ko:K15973	-	ko00000,ko03000	DNA-binding transcription factor activity
IPFFCMEA_02607	2.67e-133	yhbJ	-	-	V	-	-	-	COG1566 Multidrug resistance efflux pump
IPFFCMEA_02608	0.0	yhcA	-	-	EGP	ko:K03446	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IPFFCMEA_02609	1.4e-127	yhcB	1.6.5.2	-	S	ko:K03809	ko00130,ko01110,map00130,map01110	ko00000,ko00001,ko01000	Belongs to the WrbA family
IPFFCMEA_02610	3.95e-59	yhcC	-	-	-	-	-	-	-
IPFFCMEA_02611	2.06e-69	-	-	-	-	-	-	-	-
IPFFCMEA_02612	1.95e-78	yhcF	-	-	K	ko:K07979	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_02613	1.32e-155	yhcG	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_02614	5.09e-210	yhcH	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_02615	5.71e-211	yhcI	-	-	S	ko:K01992	-	ko00000,ko00002,ko02000	COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IPFFCMEA_02616	1.91e-42	cspB	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IPFFCMEA_02617	4.31e-192	metQ_3	-	-	M	ko:K02073	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the nlpA lipoprotein family
IPFFCMEA_02618	4.78e-249	yhcK	2.7.7.65	-	T	ko:K18967	-	ko00000,ko01000,ko02000	COG2199 FOG GGDEF domain
IPFFCMEA_02619	2.62e-301	tcyP	-	-	U	ko:K06956	-	ko00000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPFFCMEA_02620	1.22e-249	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IPFFCMEA_02621	1.5e-81	-	-	-	S	-	-	-	Immunity protein 70
IPFFCMEA_02625	6.72e-60	ydcL	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPFFCMEA_02627	4.39e-37	yddA	-	-	-	-	-	-	-
IPFFCMEA_02631	2.61e-223	yddB	-	-	S	-	-	-	Conjugative transposon protein TcpC
IPFFCMEA_02632	9.78e-54	yddC	-	-	-	-	-	-	-
IPFFCMEA_02633	6.91e-118	yddD	-	-	S	-	-	-	TcpE family
IPFFCMEA_02634	1.59e-270	yddE	-	-	S	-	-	-	AAA-like domain
IPFFCMEA_02635	2.21e-242	yddE	-	-	S	-	-	-	AAA-like domain
IPFFCMEA_02636	1.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF1874)
IPFFCMEA_02637	0.0	yddG	-	-	S	-	-	-	maturation of SSU-rRNA
IPFFCMEA_02638	1.03e-237	yddH	-	-	M	-	-	-	Lysozyme-like
IPFFCMEA_02639	3.19e-111	yddI	-	-	-	-	-	-	-
IPFFCMEA_02640	3.04e-87	yddJ	-	-	S	-	-	-	Domain of unknown function with cystatin-like fold (DUF4467)
IPFFCMEA_02641	2.1e-71	-	-	-	S	-	-	-	Domain of unknown function (DUF4145)
IPFFCMEA_02642	2.45e-83	-	-	-	S	ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_02644	9.39e-63	yhcM	-	-	-	-	-	-	-
IPFFCMEA_02645	9.32e-108	yhcN	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPFFCMEA_02646	2.37e-17	-	-	-	L	ko:K07497	-	ko00000	COG2801 Transposase and inactivated derivatives
IPFFCMEA_02647	1.22e-167	-	-	-	L	-	-	-	Phage integrase, N-terminal SAM-like domain
IPFFCMEA_02648	6.05e-53	-	-	-	S	-	-	-	SprT-like family
IPFFCMEA_02649	1.9e-23	-	-	-	S	-	-	-	YolD-like protein
IPFFCMEA_02650	5.46e-218	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IPFFCMEA_02661	5.56e-84	-	-	-	L	-	-	-	DNA (cytosine-5-)-methyltransferase activity
IPFFCMEA_02664	1.75e-37	-	-	-	-	-	-	-	-
IPFFCMEA_02667	1.91e-45	-	-	-	L	ko:K03630	-	ko00000	RadC-like JAB domain
IPFFCMEA_02669	2.43e-26	-	-	-	-	-	-	-	-
IPFFCMEA_02671	8.82e-61	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IPFFCMEA_02679	9.71e-32	-	-	-	-	-	-	-	-
IPFFCMEA_02681	8.75e-80	-	-	-	NU	-	-	-	StbA protein
IPFFCMEA_02682	6.76e-139	repE	-	-	K	-	-	-	Primase C terminal 1 (PriCT-1)
IPFFCMEA_02683	3.98e-202	-	-	-	S	-	-	-	COG0433 Predicted ATPase
IPFFCMEA_02684	6.31e-62	-	-	-	S	-	-	-	Replication-relaxation
IPFFCMEA_02686	3.82e-45	-	-	-	S	-	-	-	Conjugative transposon protein TcpC
IPFFCMEA_02689	2.29e-312	-	-	-	S	-	-	-	AAA-like domain
IPFFCMEA_02691	2.04e-60	-	-	-	A	-	-	-	Non-essential cell division protein that could be required for efficient cell constriction
IPFFCMEA_02692	4.51e-13	-	-	-	-	-	-	-	-
IPFFCMEA_02693	7.82e-143	-	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Transglycosylase SLT domain
IPFFCMEA_02695	7.68e-58	yvsG	-	-	S	ko:K07038	-	ko00000	LexA-binding, inner membrane-associated putative hydrolase
IPFFCMEA_02697	3.16e-38	-	-	-	-	-	-	-	-
IPFFCMEA_02698	8.96e-11	-	-	-	S	-	-	-	Protein of unknown function (DUF3918)
IPFFCMEA_02699	8.4e-42	yrzR	-	-	-	-	-	-	-
IPFFCMEA_02700	2.79e-105	yrrD	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02701	0.0	recD2	3.1.11.5	-	L	ko:K03581	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IPFFCMEA_02702	1.01e-20	yrrB	-	-	S	-	-	-	COG0457 FOG TPR repeat
IPFFCMEA_02703	5.64e-279	mnmA	2.8.1.13	-	J	ko:K00566	ko04122,map04122	ko00000,ko00001,ko01000,ko03016	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IPFFCMEA_02704	2.56e-270	iscS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IPFFCMEA_02705	8.12e-93	cymR	-	-	K	ko:K17472	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_02706	6.69e-301	rarA	-	-	L	ko:K07478	-	ko00000	COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IPFFCMEA_02707	2.29e-176	yrvM	-	-	H	ko:K22132	-	ko00000,ko03016	COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IPFFCMEA_02708	0.0	aspS	6.1.1.12	-	J	ko:K01876	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPFFCMEA_02709	3e-310	hisS	6.1.1.21	-	J	ko:K01892	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	histidyl-tRNA synthetase
IPFFCMEA_02711	0.0	lytH	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	COG3103 SH3 domain protein
IPFFCMEA_02712	1.36e-90	dtd	-	-	J	ko:K07560	-	ko00000,ko01000,ko03016	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IPFFCMEA_02713	0.0	relA	2.7.6.5	-	KT	ko:K00951	ko00230,map00230	ko00000,ko00001,ko01000	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPFFCMEA_02714	2.53e-118	apt	2.4.2.7	-	F	ko:K00759	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000,ko04147	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IPFFCMEA_02715	0.0	recJ	-	-	L	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	ko00000,ko00001,ko01000,ko03400	Single-stranded-DNA-specific exonuclease RecJ
IPFFCMEA_02716	1.07e-64	yrvD	-	-	S	-	-	-	Lipopolysaccharide assembly protein A domain
IPFFCMEA_02717	5.35e-113	trkA1	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IPFFCMEA_02718	0.0	secD	-	-	U	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPFFCMEA_02719	1.93e-65	yrzD	-	-	S	-	-	-	Post-transcriptional regulator
IPFFCMEA_02720	0.0	spoVB	-	-	S	ko:K06409	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPFFCMEA_02721	8.64e-145	yrbG	-	-	S	-	-	-	membrane
IPFFCMEA_02722	2.16e-98	yrzE	-	-	S	-	-	-	Protein of unknown function (DUF3792)
IPFFCMEA_02723	1.29e-52	yajC	-	-	U	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Preprotein translocase subunit YajC
IPFFCMEA_02724	4.74e-292	tgt	2.4.2.29	-	F	ko:K00773	-	ko00000,ko01000,ko03016	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IPFFCMEA_02725	6.03e-248	queA	2.4.99.17	-	J	ko:K07568	-	ko00000,ko01000,ko03016	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IPFFCMEA_02726	2.91e-30	yrzS	-	-	S	-	-	-	Protein of unknown function (DUF2905)
IPFFCMEA_02727	9.14e-239	ruvB	3.6.4.12	-	L	ko:K03551	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IPFFCMEA_02728	2.84e-137	ruvA	3.6.4.12	-	L	ko:K03550	ko03440,map03440	ko00000,ko00001,ko01000,ko03400	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IPFFCMEA_02729	6.46e-121	bofC	-	-	S	ko:K06318	-	ko00000	BofC C-terminal domain
IPFFCMEA_02730	0.0	csbX	-	-	EGP	-	-	-	the major facilitator superfamily
IPFFCMEA_02731	1.67e-247	idhA	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, NAD-binding Rossmann fold
IPFFCMEA_02732	1.91e-151	yrzF	-	-	T	-	-	-	serine threonine protein kinase
IPFFCMEA_02734	2.55e-67	-	-	-	S	-	-	-	Family of unknown function (DUF5412)
IPFFCMEA_02735	0.0	yrbD	-	-	E	ko:K03310	-	ko00000	Sodium alanine symporter
IPFFCMEA_02736	3.51e-164	yebC	-	-	K	-	-	-	transcriptional regulatory protein
IPFFCMEA_02737	5.13e-70	-	-	-	S	ko:K06345	-	ko00000	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPFFCMEA_02738	3.45e-217	safA	-	-	M	ko:K06370	-	ko00000	spore coat assembly protein SafA
IPFFCMEA_02739	4.41e-270	nadA	2.5.1.72	-	H	ko:K03517	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IPFFCMEA_02740	1.02e-201	nadC	2.4.2.19	-	H	ko:K00767	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the NadC ModD family
IPFFCMEA_02741	0.0	nadB	1.4.3.16	-	H	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of L-aspartate to iminoaspartate
IPFFCMEA_02742	1.17e-290	nifS	2.8.1.7	-	E	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	Cysteine desulfurase
IPFFCMEA_02743	5.02e-123	yrxA	-	-	S	ko:K07105	-	ko00000	small molecule binding protein (contains 3H domain)
IPFFCMEA_02744	2.54e-209	pheA	4.2.1.51	-	E	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Prephenate dehydratase
IPFFCMEA_02745	4.75e-96	pheB	5.4.99.5	-	S	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the UPF0735 family
IPFFCMEA_02746	9.66e-309	obg	-	-	S	ko:K03979	-	ko00000,ko01000,ko03009	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IPFFCMEA_02747	4.25e-139	spo0B	-	-	T	ko:K06375	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko01000	Sporulation initiation phospho-transferase B, C-terminal
IPFFCMEA_02748	2.7e-61	rpmA	-	-	J	ko:K02899	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	Belongs to the bacterial ribosomal protein bL27 family
IPFFCMEA_02749	2.66e-74	ysxB	-	-	J	ko:K07584	-	ko00000	ribosomal protein
IPFFCMEA_02750	6.34e-66	rplU	-	-	J	ko:K02888	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011	This protein binds to 23S rRNA in the presence of protein L20
IPFFCMEA_02751	1.52e-207	spoIVFB	-	-	S	ko:K06402	-	ko00000,ko01000,ko01002	Stage IV sporulation protein
IPFFCMEA_02752	7.44e-187	spoIVFA	-	-	M	ko:K06401	-	ko00000	COG0739 Membrane proteins related to metalloendopeptidases
IPFFCMEA_02753	4.13e-186	minD	-	-	D	ko:K03609	-	ko00000,ko03036,ko04812	Belongs to the ParA family
IPFFCMEA_02754	4.3e-158	minC	-	-	D	ko:K03610	-	ko00000,ko03036,ko04812	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IPFFCMEA_02755	8.72e-111	mreD	-	-	M	ko:K03571	-	ko00000,ko03036	shape-determining protein
IPFFCMEA_02756	7.78e-202	mreC	-	-	M	ko:K03570	-	ko00000,ko03036	Involved in formation and maintenance of cell shape
IPFFCMEA_02757	5.26e-235	mreB	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod shape-determining protein MreB
IPFFCMEA_02758	2.4e-162	radC	-	-	E	ko:K03630	-	ko00000	Belongs to the UPF0758 family
IPFFCMEA_02759	2.02e-131	maf	-	-	D	ko:K06287	-	ko00000	septum formation protein Maf
IPFFCMEA_02760	2.47e-210	spoIIB	-	-	S	ko:K06380	-	ko00000	Sporulation related domain
IPFFCMEA_02761	1.28e-108	comC	3.4.23.43	-	NOU	ko:K02236,ko:K02654	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IPFFCMEA_02762	6.38e-315	folC	6.3.2.12, 6.3.2.17	-	H	ko:K11754	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the folylpolyglutamate synthase family
IPFFCMEA_02763	0.0	valS	6.1.1.9	-	J	ko:K01873	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IPFFCMEA_02764	1.53e-35	-	-	-	-	-	-	-	-
IPFFCMEA_02765	2.39e-252	ysxE	-	-	S	-	-	-	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IPFFCMEA_02766	0.0	spoVID	-	-	M	ko:K06417	-	ko00000	stage VI sporulation protein D
IPFFCMEA_02767	1.44e-311	hemL	5.4.3.8	-	H	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Glutamate-1-semialdehyde aminotransferase
IPFFCMEA_02768	2.14e-232	hemB	4.2.1.24	-	H	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the ALAD family
IPFFCMEA_02769	4.13e-183	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IPFFCMEA_02770	6.27e-220	hemC	2.5.1.61	-	H	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IPFFCMEA_02771	6.56e-187	hemX	-	-	O	ko:K02497	-	ko00000	cytochrome C
IPFFCMEA_02772	6.39e-316	hemA	1.2.1.70	-	H	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IPFFCMEA_02773	4.77e-116	ysxD	-	-	-	-	-	-	-
IPFFCMEA_02774	7.6e-139	engB	-	-	D	ko:K03978	-	ko00000,ko03036	Necessary for normal cell division and for the maintenance of normal septation
IPFFCMEA_02775	0.0	lon	3.4.21.53	-	O	ko:K01338	ko04112,map04112	ko00000,ko00001,ko01000,ko01002	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPFFCMEA_02776	0.0	lonB	3.4.21.53	-	LO	ko:K04076	-	ko00000,ko01000,ko01002	Belongs to the peptidase S16 family
IPFFCMEA_02777	1.15e-296	clpX	-	-	O	ko:K03544	ko04112,map04112	ko00000,ko00001,ko03110	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IPFFCMEA_02778	5.98e-285	tig	-	-	D	ko:K03545	-	ko00000	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IPFFCMEA_02779	2.62e-238	ysoA	-	-	H	-	-	-	Tetratricopeptide repeat
IPFFCMEA_02780	4.4e-149	leuD	4.2.1.33, 4.2.1.35	-	E	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPFFCMEA_02781	0.0	leuC	4.2.1.33, 4.2.1.35	-	E	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IPFFCMEA_02782	2.04e-253	leuB	1.1.1.85	-	CE	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IPFFCMEA_02783	0.0	leuA	2.3.3.13	-	E	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IPFFCMEA_02784	9.59e-245	ilvC	1.1.1.86	-	EH	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IPFFCMEA_02785	5.05e-110	ilvN	2.2.1.6	-	E	ko:K01653,ko:K16785	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IPFFCMEA_02786	0.0	ilvB	2.2.1.6	-	E	ko:K01652,ko:K16787	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Acetolactate synthase
IPFFCMEA_02787	3.28e-46	ysnE	-	-	K	ko:K03829	-	ko00000,ko01000	acetyltransferase
IPFFCMEA_02788	3.36e-181	ysnF	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02789	0.0	ybgF	-	-	E	ko:K02205,ko:K03293,ko:K16235,ko:K16236	-	ko00000,ko02000	amino acid
IPFFCMEA_02790	1.83e-233	mmuM	2.1.1.10	-	H	ko:K00547	ko00270,ko01100,ko01110,map00270,map01100,map01110	ko00000,ko00001,ko01000	homocysteine
IPFFCMEA_02791	2.77e-37	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IPFFCMEA_02792	2.97e-270	agcS	-	-	E	ko:K03310,ko:K11626	ko02020,map02020	ko00000,ko00001	Sodium alanine symporter
IPFFCMEA_02793	4.35e-238	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IPFFCMEA_02794	5.88e-293	glnJ	2.7.13.3	-	T	ko:K07717	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_02795	5.76e-216	glnL	-	-	T	ko:K07719	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Regulator
IPFFCMEA_02796	4.1e-222	ycbC	4.2.1.41	-	EM	ko:K01707	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	5-dehydro-4-deoxyglucarate dehydratase activity
IPFFCMEA_02797	0.0	ycbD	-	-	C	ko:K22187	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPFFCMEA_02798	0.0	gudP	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_02799	0.0	gudD	4.2.1.40	-	M	ko:K01706	ko00053,ko01100,map00053,map01100	ko00000,ko00001,ko01000	Belongs to the mandelate racemase muconate lactonizing enzyme family
IPFFCMEA_02800	7.68e-160	ycbG	-	-	K	ko:K05799	-	ko00000,ko03000	FCD
IPFFCMEA_02801	0.0	garD	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IPFFCMEA_02802	3.51e-222	ycbJ	-	-	S	ko:K06979	-	br01600,ko00000,ko00002,ko01504	Macrolide 2'-phosphotransferase
IPFFCMEA_02803	8.73e-33	rtpA	-	-	K	-	-	-	Tryptophan RNA-binding attenuator protein inhibitory protein
IPFFCMEA_02804	2.85e-215	eamA1	-	-	EG	-	-	-	spore germination
IPFFCMEA_02805	5.28e-160	ycbL	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_02806	4.37e-214	ycbM	-	-	T	-	-	-	Histidine kinase
IPFFCMEA_02807	5.55e-215	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_02808	1.73e-149	-	-	-	S	-	-	-	ABC-2 family transporter protein
IPFFCMEA_02809	1.82e-75	ycbP	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IPFFCMEA_02810	1.82e-102	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IPFFCMEA_02811	1.81e-39	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
IPFFCMEA_02812	1.87e-96	tagE	2.4.1.52	GT4	M	ko:K00712	-	ko00000,ko01000,ko01003	Glycosyl transferases group 1
IPFFCMEA_02813	8.18e-07	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IPFFCMEA_02814	2.45e-34	-	-	-	K	-	-	-	Helix-turn-helix domain
IPFFCMEA_02815	3.5e-35	-	-	-	K	-	-	-	Helix-turn-helix domain
IPFFCMEA_02816	1.14e-20	-	-	-	S	-	-	-	peptidoglycan catabolic process
IPFFCMEA_02817	7.12e-37	-	-	-	-	-	-	-	-
IPFFCMEA_02818	8.25e-61	-	-	-	S	-	-	-	Restriction endonuclease
IPFFCMEA_02819	1.33e-160	ynaC	-	-	-	-	-	-	-
IPFFCMEA_02820	2.11e-66	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IPFFCMEA_02821	1.03e-305	-	-	-	I	-	-	-	Pfam Lipase (class 3)
IPFFCMEA_02822	9.96e-22	-	-	-	-	-	-	-	-
IPFFCMEA_02823	0.0	secA	-	-	U	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IPFFCMEA_02824	2.33e-231	prfB	-	-	J	ko:K02836	-	ko00000,ko03012	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPFFCMEA_02825	1.31e-184	yvjA	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPFFCMEA_02826	3.78e-74	cccB	-	-	C	ko:K12263,ko:K13300	-	ko00000	COG2010 Cytochrome c, mono- and diheme variants
IPFFCMEA_02827	3.03e-159	ftsE	-	-	D	ko:K09812	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	cell division ATP-binding protein FtsE
IPFFCMEA_02828	5.45e-199	ftsX	-	-	D	ko:K09811	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko03036	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IPFFCMEA_02829	0.0	ctpB	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IPFFCMEA_02830	1.38e-73	swrA	-	-	S	-	-	-	Swarming motility protein
IPFFCMEA_02831	3.17e-280	minJ	-	-	O	-	-	-	COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPFFCMEA_02832	3.03e-295	yvkA	-	-	P	-	-	-	-transporter
IPFFCMEA_02833	1.43e-131	yvkB	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_02834	0.0	yvkC	2.7.9.2	-	GT	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Phosphotransferase
IPFFCMEA_02835	2.54e-42	csbA	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02836	0.0	uvrB	-	-	L	ko:K03702	ko03420,map03420	ko00000,ko00001,ko03400	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IPFFCMEA_02837	0.0	uvrA	-	-	L	ko:K03701	ko03420,map03420	ko00000,ko00001,ko03400	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IPFFCMEA_02838	3.03e-147	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPFFCMEA_02839	2.25e-45	yvkN	-	-	-	-	-	-	-
IPFFCMEA_02840	8.09e-65	yvlA	-	-	-	-	-	-	-
IPFFCMEA_02841	5.54e-219	yvlB	-	-	S	-	-	-	Putative adhesin
IPFFCMEA_02842	1.5e-36	yvlC	-	-	KT	ko:K03973	-	ko00000,ko02048,ko03000	PspC domain
IPFFCMEA_02843	3.8e-66	yvlD	-	-	S	ko:K08972	-	ko00000	Membrane
IPFFCMEA_02844	1.52e-185	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPFFCMEA_02845	3.81e-28	yezD	-	-	S	-	-	-	Uncharacterized small protein (DUF2292)
IPFFCMEA_02846	4.23e-134	yetJ	-	-	S	ko:K06890	-	ko00000	Belongs to the BI1 family
IPFFCMEA_02847	1.3e-38	yetM	-	-	CH	-	-	-	FAD binding domain
IPFFCMEA_02848	5.94e-131	mrr2	-	-	L	ko:K07448	-	ko00000,ko02048	restriction endonuclease
IPFFCMEA_02849	1.94e-248	yetN	-	-	S	-	-	-	Protein of unknown function (DUF3900)
IPFFCMEA_02850	0.0	cypD	1.14.14.1, 1.6.2.4	-	C	ko:K14338	ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120	ko00000,ko00001,ko00199,ko01000	Belongs to the cytochrome P450 family
IPFFCMEA_02851	0.0	ltaS	2.7.8.20	-	M	ko:K19005	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000	Belongs to the LTA synthase family
IPFFCMEA_02852	5.07e-189	yfnH	2.7.7.33	-	JM	ko:K00978	ko00500,ko00520,ko01100,map00500,map00520,map01100	ko00000,ko00001,ko01000	Nucleotidyl transferase
IPFFCMEA_02853	4.79e-220	yfnG	4.2.1.45, 4.2.1.46	-	M	ko:K01709,ko:K01710	ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130	ko00000,ko00001,ko00002,ko01000	dehydratase
IPFFCMEA_02854	2.69e-229	yfnF	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IPFFCMEA_02855	6.7e-284	yfnE	-	-	S	-	-	-	Glycosyltransferase like family 2
IPFFCMEA_02856	2.34e-243	yfnD	-	-	M	-	-	-	Nucleotide-diphospho-sugar transferase
IPFFCMEA_02857	7.24e-267	fsr	-	-	P	ko:K08223	-	ko00000,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_02858	2.05e-165	yfnB	3.8.1.2	-	S	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	ko00000,ko00001,ko01000	Haloacid dehalogenase-like hydrolase
IPFFCMEA_02859	2.4e-312	yfnA	-	-	E	ko:K03294	-	ko00000	amino acid
IPFFCMEA_02860	0.0	yfmT	1.2.1.3, 1.2.1.67	-	C	ko:K00128,ko:K21802	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPFFCMEA_02861	5.14e-161	yfmS	-	-	NT	-	-	-	chemotaxis protein
IPFFCMEA_02862	0.0	yfmR	-	-	S	ko:K15738	-	ko00000,ko02000	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPFFCMEA_02863	4.39e-97	yfmQ	-	-	S	-	-	-	Uncharacterised protein from bacillus cereus group
IPFFCMEA_02864	3.54e-90	yfmP	-	-	K	ko:K21902	-	ko00000,ko03000	transcriptional
IPFFCMEA_02865	3.59e-265	yfmO	-	-	EGP	ko:K08221	-	ko00000,ko02000	Major facilitator superfamily
IPFFCMEA_02866	2.1e-39	-	-	-	-	-	-	-	-
IPFFCMEA_02867	3.01e-225	argF	2.1.3.3	-	E	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IPFFCMEA_02868	0.0	carB	6.3.5.5	-	EF	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase ammonia chain
IPFFCMEA_02869	3.3e-262	carA	6.3.5.5	-	F	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	ko00000,ko00001,ko00002,ko01000	Carbamoyl-phosphate synthetase glutamine chain
IPFFCMEA_02870	1.14e-276	argD	2.6.1.11, 2.6.1.17	-	E	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	acetylornithine aminotransferase
IPFFCMEA_02871	1.81e-175	argB	2.7.2.8	-	E	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the acetylglutamate kinase family. ArgB subfamily
IPFFCMEA_02872	1.37e-290	argJ	2.3.1.1, 2.3.1.35	-	E	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IPFFCMEA_02873	3.52e-253	argC	1.2.1.38	-	E	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IPFFCMEA_02874	1.68e-37	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IPFFCMEA_02875	5.71e-69	yitZ	-	-	G	-	-	-	Major Facilitator Superfamily
IPFFCMEA_02876	0.0	yitY	-	-	C	-	-	-	D-arabinono-1,4-lactone oxidase
IPFFCMEA_02877	1.74e-31	-	-	-	S	-	-	-	Proteolipid membrane potential modulator
IPFFCMEA_02878	4.63e-68	yitW	-	-	S	-	-	-	metal-sulfur cluster biosynthetic enzyme
IPFFCMEA_02879	1.19e-183	yitV	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IPFFCMEA_02880	6.18e-198	yitU	3.1.3.104	-	S	ko:K21064	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000	hydrolases of the HAD superfamily
IPFFCMEA_02881	1.92e-08	-	-	-	-	-	-	-	-
IPFFCMEA_02882	1.01e-25	-	-	-	S	-	-	-	Protein of unknown function (DUF3813)
IPFFCMEA_02883	9.69e-94	ipi	-	-	S	-	-	-	Intracellular proteinase inhibitor
IPFFCMEA_02884	2.29e-189	yitT	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPFFCMEA_02885	4.16e-198	yitS	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02886	0.0	nprB	3.4.24.28	-	E	ko:K01400,ko:K08777	ko02024,map02024	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IPFFCMEA_02887	4.59e-59	yitR	-	-	S	-	-	-	Domain of unknown function (DUF3784)
IPFFCMEA_02888	2.9e-118	-	-	-	-	-	-	-	-
IPFFCMEA_02889	8.46e-77	-	-	-	K	-	-	-	Transcriptional regulator PadR-like family
IPFFCMEA_02890	3.29e-127	-	-	-	S	-	-	-	Sporulation delaying protein SdpA
IPFFCMEA_02891	1.42e-218	-	-	-	-	-	-	-	-
IPFFCMEA_02892	2.41e-121	-	-	-	-	-	-	-	-
IPFFCMEA_02893	3.91e-204	yitL	-	-	S	ko:K00243	-	ko00000	protein conserved in bacteria
IPFFCMEA_02894	1.75e-76	yitK	-	-	S	ko:K09767	-	ko00000	Belongs to the UPF0234 family
IPFFCMEA_02895	0.0	yitJ	1.5.1.20, 2.1.1.10	-	E	ko:K00297,ko:K00547	ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IPFFCMEA_02896	2.95e-91	-	-	-	S	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_02897	1.77e-96	yitH	-	-	K	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_02898	1.52e-197	yisY	1.11.1.10	-	I	ko:K00433	-	ko00000,ko01000	hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IPFFCMEA_02899	2.15e-96	yisX	-	-	S	-	-	-	Pentapeptide repeats (9 copies)
IPFFCMEA_02900	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPFFCMEA_02901	5.19e-138	argO	-	-	S	ko:K06895	-	ko00000,ko02000	Lysine exporter protein LysE YggA
IPFFCMEA_02902	9.94e-120	yisT	-	-	S	-	-	-	DinB family
IPFFCMEA_02903	5.32e-242	yisS	1.1.1.18, 1.1.1.369, 1.1.1.370	-	S	ko:K00010,ko:K16043	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IPFFCMEA_02904	8.71e-234	rbsR	-	-	K	ko:K02529,ko:K03484	-	ko00000,ko03000	helix_turn _helix lactose operon repressor
IPFFCMEA_02905	1.41e-207	yisR	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_02906	1.68e-309	yisQ	-	-	V	-	-	-	Mate efflux family protein
IPFFCMEA_02907	3.44e-142	crtM	2.5.1.32, 2.5.1.99	-	I	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01006	phytoene
IPFFCMEA_02908	0.0	asnO	6.3.5.4	-	E	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	ko00000,ko00001,ko01000,ko01002	Asparagine synthase
IPFFCMEA_02909	6.1e-131	yisN	-	-	S	-	-	-	Protein of unknown function (DUF2777)
IPFFCMEA_02910	4.41e-131	folE	3.5.4.16	-	H	ko:K01495	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	GTP cyclohydrolase
IPFFCMEA_02911	5.13e-46	mtrB	-	-	K	ko:K06285	-	ko00000,ko03000	Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IPFFCMEA_02912	7.17e-177	hepS	2.5.1.30	-	H	ko:K00805	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IPFFCMEA_02913	5.46e-169	menG	2.1.1.163, 2.1.1.201	-	H	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IPFFCMEA_02914	4.09e-249	hepT	2.5.1.30, 2.5.1.83	-	H	ko:K00805,ko:K21275	ko00900,ko01110,map00900,map01110	ko00000,ko00001,ko01000,ko01006	Belongs to the FPP GGPP synthase family
IPFFCMEA_02915	2.17e-104	ndk	2.7.4.6	-	F	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	ko00000,ko00001,ko00002,ko01000,ko04131	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IPFFCMEA_02916	3.69e-183	cheR	2.1.1.80	-	NT	ko:K00575	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko01000,ko02035	COG1352 Methylase of chemotaxis methyl-accepting proteins
IPFFCMEA_02917	5.88e-277	aroC	4.2.3.5	-	E	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IPFFCMEA_02918	3.86e-261	aroB	4.2.3.4	-	E	ko:K01735	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IPFFCMEA_02919	9.82e-84	aroH	5.4.99.5	-	E	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IPFFCMEA_02920	0.0	trpE	4.1.3.27	-	EH	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	ko00000,ko00001,ko00002,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPFFCMEA_02921	2.37e-227	trpD	2.4.2.18, 4.1.3.27	-	E	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IPFFCMEA_02922	2.95e-145	trpC	4.1.1.48, 5.3.1.24	-	E	ko:K01609,ko:K13498	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpC family
IPFFCMEA_02923	2.6e-149	trpF	5.3.1.24	-	E	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the TrpF family
IPFFCMEA_02924	1.09e-293	trpB	4.2.1.20, 5.3.1.24	-	E	ko:K01696,ko:K01817	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IPFFCMEA_02925	3.14e-185	trpA	4.2.1.20	-	E	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IPFFCMEA_02926	2.6e-258	hisC	2.6.1.9	-	E	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPFFCMEA_02927	1.21e-264	tyrA	1.3.1.12	-	E	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	prephenate dehydrogenase
IPFFCMEA_02928	9.49e-300	aroA	2.5.1.19	-	E	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IPFFCMEA_02929	3.56e-297	ypiA	-	-	S	-	-	-	COG0457 FOG TPR repeat
IPFFCMEA_02930	1.29e-129	ypiB	-	-	S	-	-	-	Belongs to the UPF0302 family
IPFFCMEA_02931	5.55e-100	ypiF	-	-	S	-	-	-	Protein of unknown function (DUF2487)
IPFFCMEA_02932	3.35e-126	qcrA	-	-	C	ko:K03886	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Menaquinol-cytochrome c reductase
IPFFCMEA_02933	8.76e-166	qcrB	-	-	C	ko:K03887	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	COG1290 Cytochrome b subunit of the bc complex
IPFFCMEA_02934	5.71e-191	qcrC	-	-	C	ko:K03888	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002	Menaquinol-cytochrome c reductase cytochrome b c subunit
IPFFCMEA_02935	1.15e-125	ypjA	-	-	S	-	-	-	membrane
IPFFCMEA_02936	6.56e-181	ypjB	-	-	S	-	-	-	sporulation protein
IPFFCMEA_02937	3.7e-200	ypjC	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPFFCMEA_02938	1.01e-73	ypjD	-	-	S	-	-	-	Nucleotide pyrophosphohydrolase
IPFFCMEA_02939	2.4e-189	dapB	1.17.1.8	-	E	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IPFFCMEA_02940	2.52e-93	mgsA	4.2.3.3	-	G	ko:K01734	ko00640,ko01120,map00640,map01120	ko00000,ko00001,ko01000	methylglyoxal synthase
IPFFCMEA_02941	2.21e-165	bshB1	-	-	S	ko:K01463	-	ko00000,ko01000	proteins, LmbE homologs
IPFFCMEA_02942	2.45e-267	bshA	-	GT4	M	ko:K00754	-	ko00000,ko01000	N-acetyl-alpha-D-glucosaminyl L-malate synthase
IPFFCMEA_02943	1.83e-279	cca	2.7.7.72	-	J	ko:K00974	ko03013,map03013	ko00000,ko00001,ko01000,ko03016	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IPFFCMEA_02944	6.91e-234	birA	6.3.4.15	-	K	ko:K03524	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko01000,ko03000	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IPFFCMEA_02945	9.79e-194	panB	2.1.2.11	-	H	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IPFFCMEA_02946	1.57e-199	panC	6.3.2.1	-	H	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IPFFCMEA_02947	4.16e-85	panD	4.1.1.11	-	H	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IPFFCMEA_02948	0.0	dinG	3.6.4.12	-	L	ko:K03722	-	ko00000,ko01000,ko03400	helicase involved in DNA repair and perhaps also replication
IPFFCMEA_02949	1.52e-32	ypmA	-	-	S	-	-	-	Protein of unknown function (DUF4264)
IPFFCMEA_02950	2.66e-102	ypmB	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_02951	4.37e-285	aspB	2.6.1.1, 2.6.1.14	-	E	ko:K00812,ko:K22457	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IPFFCMEA_02952	0.0	asnS	6.1.1.22	-	J	ko:K01893	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	asparaginyl-tRNA
IPFFCMEA_02953	6.62e-165	dnaD	-	-	L	ko:K02086	-	ko00000	DNA replication protein DnaD
IPFFCMEA_02954	3.57e-158	nth	4.2.99.18	-	L	ko:K10773	ko03410,map03410	ko00000,ko00001,ko01000,ko03400	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPFFCMEA_02955	1.43e-121	ypoC	-	-	-	-	-	-	-
IPFFCMEA_02956	0.0	ponA	2.4.1.129, 3.4.16.4	GT51	M	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IPFFCMEA_02957	1.3e-149	recU	-	-	L	ko:K03700	-	ko00000,ko03400	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IPFFCMEA_02958	2.52e-238	yppC	-	-	S	-	-	-	Protein of unknown function (DUF2515)
IPFFCMEA_02961	7.9e-10	yppE	-	-	S	-	-	-	Bacterial domain of unknown function (DUF1798)
IPFFCMEA_02962	9.21e-11	-	-	-	S	-	-	-	YppF-like protein
IPFFCMEA_02963	8.36e-66	yppG	-	-	S	-	-	-	YppG-like protein
IPFFCMEA_02964	2.41e-92	hspX	-	-	O	ko:K06335,ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IPFFCMEA_02965	2.59e-110	ypqE	-	-	G	ko:K02777	ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111	ko00000,ko00001,ko00002,ko01000,ko02000	COG2190 Phosphotransferase system IIA components
IPFFCMEA_02966	0.0	yprA	-	-	L	ko:K06877	-	ko00000	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IPFFCMEA_02967	2.81e-298	yprB	-	-	L	ko:K07502	-	ko00000	RNase_H superfamily
IPFFCMEA_02968	1.39e-127	ypsA	-	-	S	-	-	-	Belongs to the UPF0398 family
IPFFCMEA_02969	2.97e-60	gpsB	-	-	D	-	-	-	Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IPFFCMEA_02970	1.16e-285	ypsC	-	-	L	ko:K07444	-	ko00000,ko01000	Belongs to the methyltransferase superfamily
IPFFCMEA_02972	0.0	ypvA	3.6.4.12	-	KL	ko:K03722	-	ko00000,ko01000,ko03400	COG1199 Rad3-related DNA helicases
IPFFCMEA_02973	3.12e-174	kduD	1.1.1.127	-	IQ	ko:K00065	ko00040,map00040	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_02974	7.26e-204	kduI	5.3.1.17	-	G	ko:K01815	ko00040,map00040	ko00000,ko00001,ko01000	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IPFFCMEA_02975	4.32e-235	kdgR	-	-	K	ko:K02525	-	ko00000,ko03000	transcriptional
IPFFCMEA_02976	1.15e-236	kdgK	2.7.1.45	-	G	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	COG0524 Sugar kinases, ribokinase family
IPFFCMEA_02977	5.97e-132	kdgA	4.1.2.14, 4.1.3.42	-	G	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	2-dehydro-3-deoxy-phosphogluconate aldolase
IPFFCMEA_02978	2.36e-223	kdgT	-	-	P	ko:K02526	-	ko00000,ko02000	The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
IPFFCMEA_02979	0.0	ypwA	3.4.17.19	-	E	ko:K01299	-	ko00000,ko01000,ko01002	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IPFFCMEA_02980	9.13e-126	xpt	2.4.2.22	-	F	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	ko00000,ko00001,ko01000	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IPFFCMEA_02981	8.61e-292	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IPFFCMEA_02982	1.49e-201	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IPFFCMEA_02983	4.08e-41	bcsA	-	-	Q	ko:K16167	-	ko00000,ko01008	Naringenin-chalcone synthase
IPFFCMEA_02984	1.36e-112	ypbQ	-	-	S	ko:K16168	-	ko00000,ko01008	protein conserved in bacteria
IPFFCMEA_02985	0.0	ypbR	-	-	S	-	-	-	Dynamin family
IPFFCMEA_02986	1.66e-51	ypbS	-	-	S	-	-	-	Protein of unknown function (DUF2533)
IPFFCMEA_02987	1.08e-11	-	-	-	-	-	-	-	-
IPFFCMEA_02988	2.26e-213	ypcP	-	-	L	-	-	-	5'3' exonuclease
IPFFCMEA_02989	2.59e-05	-	-	-	-	ko:K06429	-	ko00000	-
IPFFCMEA_02990	1.27e-86	rnhA	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	Ribonuclease
IPFFCMEA_02991	6.59e-136	ypdP	-	-	S	ko:K09125	-	ko00000	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IPFFCMEA_02992	1.56e-160	ypeP	3.1.26.4	-	L	ko:K03469	ko03030,map03030	ko00000,ko00001,ko01000,ko03032	COG0328 Ribonuclease HI
IPFFCMEA_02993	1.54e-37	ypeQ	-	-	S	-	-	-	Zinc-finger
IPFFCMEA_02994	1.05e-40	-	-	-	S	-	-	-	Protein of unknown function (DUF2564)
IPFFCMEA_02995	1.17e-22	degR	-	-	-	-	-	-	-
IPFFCMEA_02996	2.54e-42	cspD	-	-	K	ko:K03704	-	ko00000,ko03000	Cold-shock protein
IPFFCMEA_02997	1.28e-276	ugtP	2.4.1.315	GT28	M	ko:K03429	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko01000,ko01003	Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IPFFCMEA_02998	1.01e-223	metAA	2.3.1.46	-	E	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IPFFCMEA_02999	5.2e-113	bsaA	1.11.1.9	-	O	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	ko00000,ko00001,ko01000	Belongs to the glutathione peroxidase family
IPFFCMEA_03000	7.22e-142	yagB	-	-	S	ko:K06950	-	ko00000	phosphohydrolase
IPFFCMEA_03001	8.52e-206	ypgR	-	-	C	-	-	-	COG0694 Thioredoxin-like proteins and domains
IPFFCMEA_03002	0.0	ilvD	4.2.1.9	-	E	ko:K01687,ko:K16786	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the IlvD Edd family
IPFFCMEA_03003	9.69e-99	yphP	-	-	S	-	-	-	Belongs to the UPF0403 family
IPFFCMEA_03004	5.05e-186	ypiP	-	-	AJ	-	-	-	Putative SAM-dependent methyltransferase
IPFFCMEA_03005	2.01e-147	ypjP	-	-	S	-	-	-	YpjP-like protein
IPFFCMEA_03006	1.8e-120	ltrC	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IPFFCMEA_03007	7.88e-121	dfrA	1.5.1.3	-	H	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPFFCMEA_03008	4.7e-143	ypkP	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IPFFCMEA_03009	6.6e-142	yplQ	-	-	S	ko:K11068	-	ko00000,ko02042	protein, Hemolysin III
IPFFCMEA_03010	5.47e-234	yplP	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03011	1.04e-309	ilvA	4.3.1.19	-	E	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPFFCMEA_03012	1.28e-54	ypmP	-	-	S	-	-	-	Protein of unknown function (DUF2535)
IPFFCMEA_03013	1.24e-135	ypmQ	-	-	S	ko:K07152	-	ko00000,ko03029	protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IPFFCMEA_03014	2.58e-178	ypmR	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPFFCMEA_03015	4.59e-127	ypmS	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03016	1.24e-39	ypmT	-	-	S	-	-	-	Uncharacterized ympT
IPFFCMEA_03017	1.65e-288	mepA	-	-	V	-	-	-	MATE efflux family protein
IPFFCMEA_03018	4.14e-94	ypoP	-	-	K	-	-	-	transcriptional
IPFFCMEA_03019	9.83e-133	msrB	1.8.4.11, 1.8.4.12	-	O	ko:K07304,ko:K12267	-	ko00000,ko01000	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IPFFCMEA_03020	7.13e-103	msrB	1.8.4.12	-	O	ko:K07305	-	ko00000,ko01000	peptide methionine sulfoxide reductase
IPFFCMEA_03021	5.51e-156	-	-	-	GM	ko:K19421	-	ko00000	Polysaccharide biosynthesis protein
IPFFCMEA_03022	1.34e-278	phy	3.1.3.8	-	I	ko:K01083	ko00562,map00562	ko00000,ko00001,ko01000	Myo-inositol-hexaphosphate 3-phosphohydrolase
IPFFCMEA_03023	4.45e-226	cgeB	-	-	S	ko:K06320	-	ko00000	Spore maturation protein
IPFFCMEA_03024	3.62e-82	cgeA	-	-	-	ko:K06319	-	ko00000	-
IPFFCMEA_03025	1.76e-58	cgeC	-	-	-	ko:K06321	-	ko00000	-
IPFFCMEA_03026	0.0	cgeD	-	-	M	ko:K06322	-	ko00000	maturation of the outermost layer of the spore
IPFFCMEA_03027	1.97e-184	yiiD	-	-	K	ko:K06323	-	ko00000	acetyltransferase
IPFFCMEA_03029	3.28e-315	yodT	-	-	H	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPFFCMEA_03031	1.15e-58	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPFFCMEA_03032	3.66e-78	atoA	2.8.3.8, 2.8.3.9	-	I	ko:K01035	ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020	ko00000,ko00001,ko01000	COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IPFFCMEA_03033	0.0	yodQ	3.5.1.16, 3.5.1.18	-	E	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Acetylornithine deacetylase
IPFFCMEA_03034	3.56e-195	yodP	2.3.1.264	-	K	ko:K21935	-	ko00000,ko01000	Acetyltransferase (GNAT) family
IPFFCMEA_03035	0.0	kamA	5.4.3.2	-	E	ko:K01843	ko00310,map00310	ko00000,ko00001,ko01000	lysine 2,3-aminomutase
IPFFCMEA_03036	3.44e-63	yokU	-	-	S	-	-	-	YokU-like protein, putative antitoxin
IPFFCMEA_03037	2.1e-49	yozE	-	-	S	-	-	-	Belongs to the UPF0346 family
IPFFCMEA_03038	7.44e-159	yodN	-	-	-	-	-	-	-
IPFFCMEA_03040	5.18e-34	yozD	-	-	S	-	-	-	YozD-like protein
IPFFCMEA_03041	5.26e-134	yodM	3.6.1.27	-	I	ko:K19302	ko00550,map00550	ko00000,ko00001,ko01000,ko01011	Acid phosphatase homologues
IPFFCMEA_03042	1.17e-71	yodL	-	-	S	-	-	-	YodL-like
IPFFCMEA_03043	2.08e-12	-	-	-	-	-	-	-	-
IPFFCMEA_03044	1.68e-163	deoD	2.4.2.1	-	F	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Purine nucleoside phosphorylase
IPFFCMEA_03045	7.71e-189	yodJ	3.4.17.14	-	M	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	D-alanyl-D-alanine carboxypeptidase
IPFFCMEA_03046	2.81e-40	yodI	-	-	-	-	-	-	-
IPFFCMEA_03047	3.03e-166	yodH	-	-	Q	-	-	-	Methyltransferase
IPFFCMEA_03048	0.0	ctpA	3.4.21.102	-	M	ko:K03797	-	ko00000,ko01000,ko01002	Belongs to the peptidase S41A family
IPFFCMEA_03049	0.0	yodF	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPFFCMEA_03050	3.36e-38	-	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IPFFCMEA_03051	5.61e-222	yodE	-	-	E	ko:K15975	-	ko00000	COG0346 Lactoylglutathione lyase and related lyases
IPFFCMEA_03052	2.17e-145	yahD	-	-	S	ko:K06999	-	ko00000	Carboxylesterase
IPFFCMEA_03053	1.92e-140	yodC	-	-	C	-	-	-	nitroreductase
IPFFCMEA_03054	2.63e-73	yodB	-	-	K	-	-	-	transcriptional
IPFFCMEA_03055	5.64e-84	iolK	-	-	S	-	-	-	tautomerase
IPFFCMEA_03056	3.6e-287	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IPFFCMEA_03057	1.13e-13	-	-	-	-	-	-	-	-
IPFFCMEA_03058	8.34e-104	yozR	-	-	S	-	-	-	COG0071 Molecular chaperone (small heat shock protein)
IPFFCMEA_03059	6.68e-207	rarD	-	-	S	ko:K05786	-	ko00000,ko02000	-transporter
IPFFCMEA_03060	1.85e-58	-	-	-	-	-	-	-	-
IPFFCMEA_03061	2.32e-79	yojF	-	-	S	-	-	-	Protein of unknown function (DUF1806)
IPFFCMEA_03062	1.84e-161	yojG	-	-	S	ko:K22135	-	ko00000,ko01000	deacetylase
IPFFCMEA_03063	2.91e-193	-	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPFFCMEA_03064	1.69e-312	norM	-	-	V	ko:K03327	-	ko00000,ko02000	Multidrug efflux pump
IPFFCMEA_03066	2.14e-141	dacB	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPFFCMEA_03067	3.12e-291	yojK	-	-	CG	-	-	-	UDP-glucoronosyl and UDP-glucosyl transferase
IPFFCMEA_03068	2.48e-262	-	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IPFFCMEA_03069	4.94e-140	sodC	1.15.1.1	-	P	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	ko00000,ko00001,ko01000	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IPFFCMEA_03070	7.38e-205	yojN	-	-	S	ko:K04748	-	ko00000	ATPase family associated with various cellular activities (AAA)
IPFFCMEA_03071	0.0	yojO	-	-	P	-	-	-	Von Willebrand factor
IPFFCMEA_03072	0.0	odhA	1.2.4.2	-	C	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IPFFCMEA_03073	1.05e-263	odhB	2.3.1.61	-	C	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IPFFCMEA_03074	5.48e-213	yocS	-	-	S	ko:K03453	-	ko00000	-transporter
IPFFCMEA_03075	3.57e-299	yocR	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IPFFCMEA_03076	1.3e-206	sodF	1.15.1.1	-	P	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	ko00000,ko00001,ko01000	Superoxide dismutase
IPFFCMEA_03077	0.0	sqhC	4.2.1.137	-	I	ko:K18115	-	ko00000,ko01000	COG1657 Squalene cyclase
IPFFCMEA_03078	0.0	dhaS	1.2.1.3, 1.2.1.39	-	C	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPFFCMEA_03079	1.91e-42	yozC	-	-	-	-	-	-	-
IPFFCMEA_03080	2.17e-74	yozO	-	-	S	-	-	-	Bacterial PH domain
IPFFCMEA_03081	1.83e-49	yocN	-	-	-	-	-	-	-
IPFFCMEA_03082	2.94e-55	yozN	-	-	-	-	-	-	-
IPFFCMEA_03083	5.43e-114	yocM	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Belongs to the small heat shock protein (HSP20) family
IPFFCMEA_03084	3.93e-41	-	-	-	-	-	-	-	-
IPFFCMEA_03085	2.81e-55	yocL	-	-	-	-	-	-	-
IPFFCMEA_03086	2.87e-107	yocK	-	-	T	-	-	-	general stress protein
IPFFCMEA_03087	1.46e-147	azoR	-	-	I	ko:K01118	-	ko00000,ko01000	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IPFFCMEA_03088	0.0	recQ	3.6.4.12	-	L	ko:K03654	ko03018,map03018	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPFFCMEA_03089	6.78e-174	yocH	-	-	M	-	-	-	COG1388 FOG LysM repeat
IPFFCMEA_03091	4.71e-135	desR	-	-	T	ko:K02479,ko:K07693	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_03092	4.09e-251	desK	2.7.13.3	-	T	ko:K07778	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_03093	3.99e-258	des	1.14.19.23, 1.14.19.45	-	I	ko:K10255	ko02020,map02020	ko00000,ko00001,ko01000,ko01004	fatty acid desaturase
IPFFCMEA_03094	1.41e-242	yocD	3.4.17.13	-	V	ko:K01297	-	ko00000,ko01000,ko01002,ko01011	peptidase S66
IPFFCMEA_03095	7.04e-118	yocC	-	-	-	-	-	-	-
IPFFCMEA_03096	8.69e-184	-	-	-	-	-	-	-	-
IPFFCMEA_03097	3.97e-119	yozB	-	-	S	ko:K08976	-	ko00000	membrane
IPFFCMEA_03100	0.0	glmS	2.6.1.16	-	M	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	ko00000,ko00001,ko01000,ko01002	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IPFFCMEA_03101	0.0	glmM	5.4.2.10	-	G	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	ko00000,ko00001,ko01000	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPFFCMEA_03102	3.55e-291	ybbR	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03103	5.43e-189	dacA	2.7.7.85	-	S	ko:K18672	-	ko00000,ko01000	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IPFFCMEA_03104	3.19e-151	rsiW	-	-	K	-	-	-	Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IPFFCMEA_03105	9.27e-127	sigW	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_03111	9.88e-100	ybbK	-	-	S	-	-	-	Protein of unknown function (DUF523)
IPFFCMEA_03112	8.99e-114	ybbJ	-	-	J	-	-	-	acetyltransferase
IPFFCMEA_03113	1.64e-210	murQ	4.2.1.126	-	G	ko:K07106	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IPFFCMEA_03114	3.14e-193	ybbH	-	-	K	-	-	-	transcriptional
IPFFCMEA_03115	2.09e-303	ybbF	2.7.1.211	-	G	ko:K02808,ko:K02809,ko:K02810	ko00500,ko02060,map00500,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_03116	0.0	ybbE	3.4.16.4	-	V	ko:K21469	ko00550,map00550	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the UPF0214 family
IPFFCMEA_03117	0.0	ybbD	3.2.1.52	-	G	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	ko00000,ko00001,ko00002,ko01000	Belongs to the glycosyl hydrolase 3 family
IPFFCMEA_03118	8.03e-21	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03119	6.63e-270	ybbC	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03120	0.0	ybbB	-	-	K	ko:K21701	-	ko00000,ko03000	COG2207 AraC-type DNA-binding domain-containing proteins
IPFFCMEA_03121	2.54e-216	feuA	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Iron-uptake system-binding protein
IPFFCMEA_03122	5.81e-226	feuB	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_03123	1.43e-227	feuC	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_03124	7.76e-182	ybbA	-	-	S	ko:K07017	-	ko00000	Putative esterase
IPFFCMEA_03125	5.36e-203	ybaS	-	-	S	-	-	-	Na -dependent transporter
IPFFCMEA_03127	0.0	ybaR	-	-	P	ko:K03321	-	ko00000,ko02000	COG0659 Sulfate permease and related transporters (MFS superfamily)
IPFFCMEA_03128	2.13e-150	tuaA	-	-	M	-	-	-	COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IPFFCMEA_03129	1.82e-300	tuaB	-	-	S	ko:K03328,ko:K16694,ko:K16695	-	ko00000,ko02000	COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IPFFCMEA_03130	4.98e-256	tuaC	-	GT4	GM	ko:K16697	-	ko00000,ko01000,ko01003	Teichuronic acid
IPFFCMEA_03131	1.16e-301	tuaD	1.1.1.22	-	M	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IPFFCMEA_03133	4.47e-315	tuaE	-	-	M	ko:K16705	-	ko00000	Teichuronic acid biosynthesis protein
IPFFCMEA_03134	4.16e-137	tuaF	-	-	M	ko:K16706	-	ko00000	protein involved in exopolysaccharide biosynthesis
IPFFCMEA_03135	1.33e-174	tuaG	-	GT2	M	ko:K16698	-	ko00000,ko01000,ko01003	Glycosyltransferase like family 2
IPFFCMEA_03136	7.15e-298	tuaH	-	-	M	ko:K16699	-	ko00000,ko01000,ko01003	Teichuronic acid biosynthesis glycosyltransferase tuaH
IPFFCMEA_03137	2.99e-231	tagO	2.7.8.33, 2.7.8.35	-	M	ko:K02851	-	ko00000,ko01000,ko01003,ko01005	COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IPFFCMEA_03139	4.26e-100	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_03142	1.03e-50	-	-	-	S	-	-	-	Psort location CytoplasmicMembrane, score
IPFFCMEA_03146	1.23e-151	-	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03147	1.94e-136	yvyE	3.4.13.9	-	S	ko:K01271	-	ko00000,ko01000,ko01002	Domain of unknown function (DUF1949)
IPFFCMEA_03148	2.94e-247	degS	2.7.13.3	-	T	ko:K07777	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IPFFCMEA_03149	2.92e-162	degU	-	-	KT	ko:K02479,ko:K07692	ko02020,ko02024,map02020,map02024	ko00000,ko00001,ko00002,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_03150	1.24e-198	degV	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03151	0.0	comFA	-	-	L	ko:K02240	-	ko00000,ko00002,ko02044	COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IPFFCMEA_03152	1.26e-61	comFB	-	-	S	ko:K02241	-	ko00000,ko00002,ko02044	Late competence development protein ComFB
IPFFCMEA_03153	2.26e-162	comFC	-	-	S	ko:K02242	-	ko00000,ko00002,ko02044	Phosphoribosyl transferase domain
IPFFCMEA_03154	1.06e-95	yvyF	-	-	S	-	-	-	flagellar protein
IPFFCMEA_03155	8.72e-53	flgM	-	-	KNU	ko:K02398	ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040	ko00000,ko00001,ko02035	Negative regulator of flagellin synthesis
IPFFCMEA_03156	7.06e-102	yvyG	-	-	NOU	-	-	-	FlgN protein
IPFFCMEA_03157	0.0	flgK	-	-	N	ko:K02396	ko02040,map02040	ko00000,ko00001,ko02035	flagellar hook-associated protein
IPFFCMEA_03158	7.66e-197	flgL	-	-	N	ko:K02397	ko02040,map02040	ko00000,ko00001,ko02035	Belongs to the bacterial flagellin family
IPFFCMEA_03159	6.92e-92	yviE	-	-	-	-	-	-	-
IPFFCMEA_03160	1.23e-96	fliW	-	-	S	ko:K13626	-	ko00000,ko02035	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IPFFCMEA_03161	1.05e-40	csrA	-	-	T	ko:K03563	ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111	ko00000,ko00001,ko03019	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IPFFCMEA_03162	4.34e-157	hag	-	-	N	ko:K02406	ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134	ko00000,ko00001,ko02035	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IPFFCMEA_03163	3.03e-74	flaG	-	-	N	ko:K06603	-	ko00000,ko02035	flagellar protein FlaG
IPFFCMEA_03164	0.0	fliD	-	-	N	ko:K02407	ko02040,map02040	ko00000,ko00001,ko02035	morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IPFFCMEA_03165	6.02e-90	fliS	-	-	N	ko:K02422	ko02040,map02040	ko00000,ko00001,ko02035	flagellar protein FliS
IPFFCMEA_03166	8.69e-09	fliT	-	-	S	ko:K02423	ko02040,map02040	ko00000,ko00001,ko02035	bacterial-type flagellum organization
IPFFCMEA_03167	2.46e-67	-	-	-	-	-	-	-	-
IPFFCMEA_03168	1.73e-132	hpf	-	-	J	ko:K05808	-	ko00000,ko03009	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPFFCMEA_03169	0.0	gyrA	5.99.1.3	-	L	ko:K02469	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPFFCMEA_03170	0.0	gyrB	5.99.1.3	-	L	ko:K02470	-	ko00000,ko01000,ko03032,ko03400	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPFFCMEA_03171	1.25e-51	yaaB	-	-	S	-	-	-	Domain of unknown function (DUF370)
IPFFCMEA_03172	1.85e-263	recF	-	-	L	ko:K03629	ko03440,map03440	ko00000,ko00001,ko03400	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPFFCMEA_03173	2.24e-45	yaaA	-	-	S	ko:K14761	-	ko00000,ko03009	S4 domain
IPFFCMEA_03174	9.88e-263	dnaN	2.7.7.7	-	L	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IPFFCMEA_03175	0.0	dnaA	-	-	L	ko:K02313	ko02020,ko04112,map02020,map04112	ko00000,ko00001,ko03032,ko03036	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPFFCMEA_03176	1.64e-70	rnpA	3.1.26.5	-	J	ko:K03536	-	ko00000,ko01000,ko03016	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IPFFCMEA_03177	9.29e-179	yidC	-	-	U	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	ko00000,ko00001,ko00002,ko02044,ko03029	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IPFFCMEA_03178	4.32e-140	jag	-	-	S	ko:K06346	-	ko00000	single-stranded nucleic acid binding R3H
IPFFCMEA_03179	0.0	mnmE	-	-	S	ko:K03650	-	ko00000,ko01000,ko03016	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPFFCMEA_03180	0.0	gidA	-	-	D	ko:K03495	-	ko00000,ko03016,ko03036	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IPFFCMEA_03181	8.33e-167	rsmG	2.1.1.170	-	J	ko:K03501	-	ko00000,ko01000,ko03009,ko03036	Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IPFFCMEA_03182	9e-193	noc	-	-	D	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IPFFCMEA_03183	3.77e-97	-	-	-	S	-	-	-	Bacterial PH domain
IPFFCMEA_03184	4.79e-173	soj	-	-	D	ko:K03496	-	ko00000,ko03036,ko04812	COG1192 ATPases involved in chromosome partitioning
IPFFCMEA_03185	3.96e-191	spo0J	-	-	K	ko:K03497	-	ko00000,ko03000,ko03036,ko04812	Belongs to the ParB family
IPFFCMEA_03186	3.26e-72	-	-	-	L	-	-	-	transposase activity
IPFFCMEA_03187	2.88e-186	-	-	-	L	ko:K07497	-	ko00000	Molecular Function DNA binding, Biological Process DNA recombination
IPFFCMEA_03189	0.0	gerKA	-	-	EG	ko:K06295,ko:K06307	-	ko00000	Spore germination protein
IPFFCMEA_03190	1.22e-289	gerKC	-	-	S	ko:K06297	-	ko00000	spore germination
IPFFCMEA_03191	5.28e-244	gerKB	-	-	F	ko:K06296	-	ko00000,ko02000	Spore germination protein
IPFFCMEA_03192	1.33e-152	yclH	-	-	P	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter
IPFFCMEA_03193	5.23e-274	yclI	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	ABC transporter (permease) YclI
IPFFCMEA_03194	2.09e-164	yclJ	-	-	T	ko:K02483	-	ko00000,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_03195	0.0	yclK	-	-	T	-	-	-	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IPFFCMEA_03196	7.71e-98	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPFFCMEA_03198	7.93e-06	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IPFFCMEA_03199	0.0	lysC	2.7.2.4	-	E	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the aspartokinase family
IPFFCMEA_03201	1.09e-205	yclN	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_03202	3.16e-209	yclO	-	-	P	ko:K02015	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IPFFCMEA_03203	2.29e-175	yclP	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_03204	4.69e-212	yclQ	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4607 ABC-type enterochelin transport system, periplasmic component
IPFFCMEA_03205	0.0	ycnB	-	-	EGP	-	-	-	the major facilitator superfamily
IPFFCMEA_03206	5.87e-198	ycnC	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03207	2.12e-174	-	1.5.1.39	-	C	ko:K10678,ko:K19286	ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120	ko00000,ko00001,ko01000	Oxidoreductase
IPFFCMEA_03208	1.68e-60	ycnE	-	-	S	-	-	-	Monooxygenase
IPFFCMEA_03209	6.51e-69	yczG	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IPFFCMEA_03210	0.0	gabR	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPFFCMEA_03211	3.26e-311	gabT	2.6.1.19, 2.6.1.22	-	E	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko01007	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPFFCMEA_03212	0.0	gabD	1.2.1.16, 1.2.1.20, 1.2.1.79	-	C	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPFFCMEA_03213	1.67e-190	glcU	-	-	U	ko:K05340	-	ko00000,ko02000	Glucose uptake
IPFFCMEA_03214	3.27e-184	gdh	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_03215	1.34e-132	ycnI	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03216	0.0	ycnJ	-	-	P	ko:K14166	-	ko00000,ko02000	protein, homolog of Cu resistance protein CopC
IPFFCMEA_03217	2.03e-136	ycnK	-	-	K	ko:K21601	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IPFFCMEA_03218	1.34e-74	-	-	-	-	-	-	-	-
IPFFCMEA_03219	0.0	mtlA	2.7.1.197	-	G	ko:K02799,ko:K02800	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG2213 Phosphotransferase system, mannitol-specific IIBC component
IPFFCMEA_03220	8.3e-95	mtlF	2.7.1.197	-	G	ko:K02798	ko00051,ko02060,map00051,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IPFFCMEA_03221	1.41e-264	mtlD	1.1.1.17	-	G	ko:K00009	ko00051,map00051	ko00000,ko00001,ko01000	COG0246 Mannitol-1-phosphate altronate dehydrogenases
IPFFCMEA_03222	1.01e-256	ycsA	1.1.1.83, 1.1.1.93, 4.1.1.73	-	CE	ko:K07246	ko00630,ko00650,map00630,map00650	ko00000,ko00001,ko01000	Tartrate dehydrogenase
IPFFCMEA_03224	1.25e-96	lepB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPFFCMEA_03225	1.32e-24	-	-	-	Q	-	-	-	COG0412 Dienelactone hydrolase and related enzymes
IPFFCMEA_03226	2.68e-87	ycsD	4.2.1.59	-	I	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	FabA-like domain
IPFFCMEA_03243	1.62e-207	ydjN	-	-	U	-	-	-	Involved in the tonB-independent uptake of proteins
IPFFCMEA_03244	1.79e-84	ydjM	-	-	M	-	-	-	Lytic transglycolase
IPFFCMEA_03245	3.5e-249	ydjL	1.1.1.264, 1.1.1.303, 1.1.1.4	-	E	ko:K00004,ko:K00098	ko00650,map00650	ko00000,ko00001,ko01000	Dehydrogenase
IPFFCMEA_03246	0.0	iolT	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPFFCMEA_03247	1.91e-33	-	-	-	S	-	-	-	Ion transport 2 domain protein
IPFFCMEA_03248	4.11e-183	-	-	-	S	-	-	-	Ion transport 2 domain protein
IPFFCMEA_03249	3.61e-203	ydjI	-	-	S	-	-	-	virion core protein (lumpy skin disease virus)
IPFFCMEA_03250	3.21e-167	ydjH	-	-	S	ko:K06872	-	ko00000	COG1512 Beta-propeller domains of methanol dehydrogenase type
IPFFCMEA_03251	3.64e-228	ydjG	-	-	L	-	-	-	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPFFCMEA_03252	8.88e-147	pspA	-	-	KT	ko:K03969	-	ko00000	Phage shock protein A
IPFFCMEA_03253	4.95e-220	ydjE	2.7.1.4	-	G	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	ko00000,ko00001,ko01000	pfkB family carbohydrate kinase
IPFFCMEA_03254	0.0	gutP	-	-	G	ko:K03292,ko:K16248	-	ko00000,ko02000	MFS/sugar transport protein
IPFFCMEA_03255	2.5e-257	gutB	1.1.1.14	-	E	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	ko00000,ko00001,ko00002,ko01000	Dehydrogenase
IPFFCMEA_03256	0.0	gutR	-	-	K	ko:K16247	-	ko00000,ko03000	NB-ARC domain
IPFFCMEA_03257	5.53e-175	-	-	-	-	-	-	-	-
IPFFCMEA_03258	1.17e-148	-	-	-	-	-	-	-	-
IPFFCMEA_03262	5.85e-35	-	-	-	U	-	-	-	Preprotein translocase subunit SecB
IPFFCMEA_03264	6.75e-38	-	-	-	K	-	-	-	Helix-turn-helix domain
IPFFCMEA_03266	7.52e-55	-	-	-	S	-	-	-	protein domain associated with
IPFFCMEA_03268	6.57e-233	-	-	-	A	ko:K21491	-	ko00000,ko01000,ko02048	Pre-toxin TG
IPFFCMEA_03269	8.88e-87	-	-	-	S	-	-	-	Immunity protein 70
IPFFCMEA_03270	7.81e-167	xlyB	3.5.1.28	-	M	ko:K01447	-	ko00000,ko01000	N-acetylmuramoyl-L-alanine amidase
IPFFCMEA_03271	3.19e-41	xhlB	-	-	S	-	-	-	SPP1 phage holin
IPFFCMEA_03272	1.81e-37	bhlA	-	-	S	-	-	-	BhlA holin family
IPFFCMEA_03275	2.23e-90	-	-	-	S	-	-	-	Regulatory protein YrvL
IPFFCMEA_03276	9.3e-126	ymcC	-	-	S	-	-	-	Membrane
IPFFCMEA_03277	1.02e-134	pksA	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03278	8.03e-81	ymzB	-	-	-	-	-	-	-
IPFFCMEA_03279	6.55e-208	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IPFFCMEA_03280	0.0	aprX	-	-	O	ko:K17734	-	ko00000,ko01000,ko01002	Belongs to the peptidase S8 family
IPFFCMEA_03282	3.96e-163	ymaC	-	-	S	-	-	-	Replication protein
IPFFCMEA_03283	1.03e-105	ymaD	-	-	O	-	-	-	redox protein, regulator of disulfide bond formation
IPFFCMEA_03284	1.57e-73	ebrB	-	-	P	ko:K03297,ko:K11814,ko:K11815	-	ko00000,ko00002,ko02000	COG2076 Membrane transporters of cations and cationic drugs
IPFFCMEA_03285	2.45e-67	ebrA	-	-	P	ko:K11814	-	ko00000,ko00002,ko02000	Small Multidrug Resistance protein
IPFFCMEA_03287	5.41e-76	ymaF	-	-	S	-	-	-	YmaF family
IPFFCMEA_03288	3.95e-223	miaA	2.5.1.75	-	J	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	ko00000,ko00001,ko01000,ko01006,ko03016	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPFFCMEA_03289	1.28e-45	hfq	-	-	J	ko:K03666	ko02024,ko03018,ko05111,map02024,map03018,map05111	ko00000,ko00001,ko03019,ko03036	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IPFFCMEA_03290	1.63e-31	-	-	-	-	-	-	-	-
IPFFCMEA_03291	1.2e-30	ymzA	-	-	-	-	-	-	-
IPFFCMEA_03292	5.01e-66	nrdI	-	-	F	ko:K03647	-	ko00000	Probably involved in ribonucleotide reductase function
IPFFCMEA_03293	0.0	nrdE	1.17.4.1	-	F	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPFFCMEA_03294	1.65e-243	nrdF	1.17.4.1	-	F	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPFFCMEA_03295	2.24e-141	-	-	-	-	-	-	-	-
IPFFCMEA_03296	1.16e-149	cwlC	3.5.1.28	-	M	ko:K01448	ko01503,map01503	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	n-acetylmuramoyl-L-alanine amidase
IPFFCMEA_03297	2.29e-226	spoVK	-	-	O	ko:K06413	-	ko00000	stage V sporulation protein K
IPFFCMEA_03298	1.82e-293	hflX	-	-	S	ko:K03665	-	ko00000,ko03009	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPFFCMEA_03299	1.37e-309	ynbB	-	-	P	-	-	-	COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IPFFCMEA_03300	9.94e-90	glnR	-	-	K	ko:K03713,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000,ko03000	transcriptional
IPFFCMEA_03301	0.0	glnA	6.3.1.2	-	E	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	ko00000,ko00001,ko01000,ko04147	glutamine synthetase
IPFFCMEA_03302	3.69e-32	-	-	-	-	-	-	-	-
IPFFCMEA_03303	1.68e-53	-	-	-	-	-	-	-	-
IPFFCMEA_03304	4.6e-309	-	-	-	M	-	-	-	nucleic acid phosphodiester bond hydrolysis
IPFFCMEA_03306	1.68e-13	-	-	-	-	-	-	-	-
IPFFCMEA_03308	1.46e-105	-	-	-	-	-	-	-	-
IPFFCMEA_03309	4.13e-51	-	-	-	-	-	-	-	-
IPFFCMEA_03310	4.13e-116	-	-	-	G	-	-	-	SMI1-KNR4 cell-wall
IPFFCMEA_03311	9.3e-51	ynaC	-	-	-	-	-	-	-
IPFFCMEA_03312	3.65e-81	ynaC	-	-	-	-	-	-	-
IPFFCMEA_03313	3.02e-117	-	-	-	L	-	-	-	Replication protein
IPFFCMEA_03314	4.78e-32	-	-	-	-	-	-	-	-
IPFFCMEA_03315	8.23e-39	-	-	-	-	-	-	-	-
IPFFCMEA_03317	9.8e-302	pre	-	-	D	-	-	-	plasmid recombination enzyme
IPFFCMEA_03318	6.29e-100	-	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03321	1.12e-154	rapE	-	-	S	ko:K06363	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IPFFCMEA_03322	6.22e-224	-	-	-	L	-	-	-	Replication protein
IPFFCMEA_03323	9.8e-22	-	-	-	-	-	-	-	-
IPFFCMEA_03324	1.02e-27	-	-	-	K	ko:K07729	-	ko00000,ko03000	Helix-turn-helix XRE-family like proteins
IPFFCMEA_03325	0.0	-	-	-	IQ	ko:K15641,ko:K16398,ko:K16417,ko:K20788	ko01052,map01052	ko00000,ko00001,ko01008	PKS_KR
IPFFCMEA_03326	1.42e-56	-	-	-	S	-	-	-	MepB protein
IPFFCMEA_03327	8.33e-58	-	-	-	S	-	-	-	Metallo-beta-lactamase superfamily
IPFFCMEA_03328	0.0	ndhF	1.6.5.3	-	CP	ko:K05577	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IPFFCMEA_03329	0.0	ybcC	-	-	S	ko:K09822	-	ko00000	Belongs to the UPF0753 family
IPFFCMEA_03330	1.34e-120	ybcF	-	-	P	-	-	-	carbonic anhydrase
IPFFCMEA_03331	5.59e-64	-	-	-	-	-	-	-	-
IPFFCMEA_03332	3.6e-80	ybcI	-	-	S	-	-	-	Uncharacterized conserved protein (DUF2294)
IPFFCMEA_03333	1.55e-65	-	-	-	T	ko:K02483	-	ko00000,ko02022	Transcriptional regulatory protein, C terminal
IPFFCMEA_03334	1.89e-70	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
IPFFCMEA_03335	2.05e-131	-	-	-	T	-	-	-	His Kinase A (phospho-acceptor) domain
IPFFCMEA_03337	3.26e-177	ybdM	2.7.11.1	-	KLT	ko:K08884	-	ko00000,ko01000,ko01001	Protein tyrosine kinase
IPFFCMEA_03338	1.49e-192	ybdN	-	-	-	-	-	-	-
IPFFCMEA_03339	4.65e-276	ybdO	-	-	S	-	-	-	Domain of unknown function (DUF4885)
IPFFCMEA_03340	0.0	ybxG	-	-	E	ko:K03293	-	ko00000	COG1113 Gamma-aminobutyrate permease and related permeases
IPFFCMEA_03341	1.88e-172	adcB	-	-	P	ko:K09816	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IPFFCMEA_03342	2.32e-169	adcC	-	-	P	ko:K02074,ko:K09817	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IPFFCMEA_03343	1.95e-221	adcA	-	-	P	ko:K09815	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the bacterial solute-binding protein 9 family
IPFFCMEA_03344	0.0	malL	3.2.1.10, 3.2.1.20	GH13,GH31	G	ko:K01182,ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	ko00000,ko00001,ko01000	COG0366 Glycosidases
IPFFCMEA_03345	7.67e-177	-	1.1.1.47	-	IQ	ko:K00034	ko00030,ko01120,ko01200,map00030,map01120,map01200	ko00000,ko00001,ko01000	Enoyl-(Acyl carrier protein) reductase
IPFFCMEA_03346	1.65e-247	rapJ	-	-	S	ko:K06368	-	ko00000,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_03347	1.53e-122	-	-	-	M	ko:K17733	-	ko00000,ko01000,ko01002,ko01011	D-alanyl-D-alanine carboxypeptidase
IPFFCMEA_03348	0.0	ycdC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_03349	0.0	ycdB	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_03350	6.38e-229	ycdA	-	-	S	-	-	-	Domain of unknown function (DUF5105)
IPFFCMEA_03351	4.58e-68	yccK	-	-	C	-	-	-	Aldo keto reductase
IPFFCMEA_03352	2.9e-28	yccK	-	-	C	-	-	-	Aldo keto reductase
IPFFCMEA_03353	9.75e-258	-	-	-	CP	ko:K09696	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPFFCMEA_03354	5.41e-171	natA	3.6.3.7	-	CP	ko:K01990,ko:K09697	ko02010,ko02020,map02010,map02020	ko00000,ko00001,ko00002,ko01000,ko02000	ATPases associated with a variety of cellular activities
IPFFCMEA_03355	6.86e-163	natR	-	-	T	ko:K02477,ko:K11641	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	LytTr DNA-binding domain
IPFFCMEA_03356	6.18e-213	natK	2.7.13.3	-	T	ko:K11640	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	GHKL domain
IPFFCMEA_03357	7.13e-255	yccF	-	-	K	ko:K07039	-	ko00000	SEC-C motif
IPFFCMEA_03358	4.32e-78	-	-	-	S	-	-	-	RDD family
IPFFCMEA_03359	4e-147	-	3.1.1.3	-	S	ko:K01046	ko00561,ko01100,map00561,map01100	ko00000,ko00001,ko00002,ko01000	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IPFFCMEA_03360	8.02e-256	ansB	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IPFFCMEA_03361	7.64e-131	lmrA	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IPFFCMEA_03362	1.45e-301	lmrB	-	-	EGP	ko:K18926	-	ko00000,ko00002,ko02000	the major facilitator superfamily
IPFFCMEA_03363	1.39e-258	ycbU	-	-	E	-	-	-	Selenocysteine lyase
IPFFCMEA_03364	4.68e-152	pcp	3.4.19.3	-	O	ko:K01304	-	ko00000,ko01000,ko01002	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IPFFCMEA_03365	3.61e-158	tatC	-	-	U	ko:K03118	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IPFFCMEA_03366	3.12e-38	tatAD	-	-	U	ko:K03116	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02044	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IPFFCMEA_03367	0.0	phoD	3.1.3.1	-	P	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko01000	COG3540 Phosphodiesterase alkaline phosphatase D
IPFFCMEA_03368	3.83e-174	ycbR	-	-	T	-	-	-	vWA found in TerF C terminus
IPFFCMEA_03369	1.46e-283	capB	-	-	M	ko:K01932	-	ko00000,ko01000	COG0769 UDP-N-acetylmuramyl tripeptide synthase
IPFFCMEA_03370	8.44e-91	capC	-	-	S	ko:K22116	-	ko00000	biosynthesis protein
IPFFCMEA_03371	1.33e-277	capA	-	-	M	ko:K07282	-	ko00000	enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IPFFCMEA_03372	2.29e-29	ywtC	-	-	-	-	-	-	-
IPFFCMEA_03373	2.51e-39	yjzC	-	-	S	-	-	-	YjzC-like protein
IPFFCMEA_03374	2.17e-23	yjzD	-	-	S	-	-	-	Protein of unknown function (DUF2929)
IPFFCMEA_03375	5.69e-181	yjaU	-	-	I	-	-	-	carboxylic ester hydrolase activity
IPFFCMEA_03376	5.2e-132	yjaV	-	-	-	-	-	-	-
IPFFCMEA_03377	5.26e-234	med	-	-	S	ko:K05519,ko:K07335	-	ko00000,ko03000	Transcriptional activator protein med
IPFFCMEA_03378	8.86e-35	comZ	-	-	S	ko:K02254	-	ko00000,ko02044	ComZ
IPFFCMEA_03379	2.67e-38	yjzB	-	-	-	-	-	-	-
IPFFCMEA_03380	1.61e-221	fabH	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPFFCMEA_03381	3.06e-302	fabF	2.3.1.179	-	I	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IPFFCMEA_03382	9.48e-193	yjaZ	-	-	O	-	-	-	Zn-dependent protease
IPFFCMEA_03383	6.15e-234	appD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_03384	2.82e-235	appF	-	-	E	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_03385	0.0	appA	-	-	E	ko:K02035	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0747 ABC-type dipeptide transport system, periplasmic component
IPFFCMEA_03386	1.04e-219	appB	-	-	P	ko:K02033	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPFFCMEA_03387	8.44e-208	appC	-	-	EP	ko:K02034	ko02024,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPFFCMEA_03388	3.18e-190	yjbA	-	-	S	-	-	-	Belongs to the UPF0736 family
IPFFCMEA_03389	6.15e-235	trpS	6.1.1.2	-	J	ko:K01867	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Tryptophanyl-tRNA synthetase
IPFFCMEA_03390	0.0	oppA	-	-	E	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	ABC transporter substrate-binding protein
IPFFCMEA_03391	3.44e-211	oppB	-	-	P	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPFFCMEA_03392	7.55e-212	oppC	-	-	EP	ko:K15582,ko:K16201	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IPFFCMEA_03393	3.92e-249	oppD	-	-	P	ko:K02031,ko:K15583,ko:K16202	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_03394	4.43e-220	oppF	-	-	E	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_03395	1.18e-267	yjbB	-	-	EGP	-	-	-	Major Facilitator Superfamily
IPFFCMEA_03396	2.77e-54	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_03397	1.41e-63	yjbC	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_03398	1.01e-87	spxA	-	-	K	ko:K16509	-	ko00000	Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IPFFCMEA_03399	4.1e-143	yjbE	-	-	P	-	-	-	Integral membrane protein TerC family
IPFFCMEA_03400	3.98e-150	mecA	-	-	NOT	ko:K16511	-	ko00000	Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IPFFCMEA_03401	9.9e-279	coiA	-	-	S	ko:K06198	-	ko00000	Competence protein
IPFFCMEA_03402	0.0	pepF	-	-	E	ko:K08602	-	ko00000,ko01000,ko01002	oligoendopeptidase F
IPFFCMEA_03403	2.68e-28	-	-	-	-	-	-	-	-
IPFFCMEA_03404	1.32e-218	yjbH	-	-	Q	-	-	-	dithiol-disulfide isomerase involved in polyketide biosynthesis
IPFFCMEA_03405	8.58e-94	yjbI	-	-	S	ko:K06886	-	ko00000	Bacterial-like globin
IPFFCMEA_03406	3.61e-122	yjbJ	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPFFCMEA_03407	7.02e-128	yjbK	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03408	4.41e-80	yjbL	-	-	S	-	-	-	Belongs to the UPF0738 family
IPFFCMEA_03409	5.06e-145	yjbM	2.7.6.5	-	S	ko:K07816	ko00230,map00230	ko00000,ko00001,ko01000	GTP pyrophosphokinase
IPFFCMEA_03410	2.94e-194	nadK	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPFFCMEA_03411	3.01e-202	rluD	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IPFFCMEA_03412	1.15e-180	prpE	3.1.3.16, 3.6.1.41	-	T	ko:K01090,ko:K01525	ko00230,map00230	ko00000,ko00001,ko01000	Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IPFFCMEA_03413	0.0	yjbQ	-	-	P	ko:K03455,ko:K03499	-	ko00000,ko02000	Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IPFFCMEA_03414	1.91e-175	tenA	3.5.99.2	-	K	ko:K03707	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IPFFCMEA_03415	4.49e-136	tenI	5.3.99.10	-	H	ko:K10810	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000,ko03000	Transcriptional regulator TenI
IPFFCMEA_03416	1.73e-272	thiO	1.4.3.19, 1.4.5.1	-	E	ko:K00285,ko:K03153	ko00360,ko00730,ko01100,map00360,map00730,map01100	ko00000,ko00001,ko01000	Glycine oxidase
IPFFCMEA_03417	2.56e-40	thiS	-	-	H	ko:K03154	ko04122,map04122	ko00000,ko00001	thiamine diphosphate biosynthetic process
IPFFCMEA_03418	1.86e-171	thiG	2.8.1.10	-	H	ko:K03149	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IPFFCMEA_03419	2.41e-235	thiF	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IPFFCMEA_03420	4.85e-191	thiD	2.7.1.49, 2.7.4.7	-	H	ko:K00941	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko00002,ko01000	Phosphomethylpyrimidine kinase
IPFFCMEA_03421	1.23e-182	fabI	1.3.1.10, 1.3.1.9	-	I	ko:K00208	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Enoyl- acyl-carrier-protein reductase NADH
IPFFCMEA_03422	2.09e-103	yjbX	-	-	S	-	-	-	Spore coat protein
IPFFCMEA_03423	3.92e-107	cotZ	-	-	S	ko:K06344	-	ko00000	Spore coat protein
IPFFCMEA_03424	6.3e-124	cotY	-	-	S	ko:K06343	-	ko00000	Spore coat protein Z
IPFFCMEA_03425	1.03e-62	cotX	-	-	S	ko:K06342	-	ko00000	Spore Coat Protein X and V domain
IPFFCMEA_03426	1.51e-18	cotW	-	-	-	ko:K06341	-	ko00000	-
IPFFCMEA_03428	1.23e-75	yjcA	-	-	S	-	-	-	Protein of unknown function (DUF1360)
IPFFCMEA_03431	5.39e-52	spoVIF	-	-	S	-	-	-	Stage VI sporulation protein F
IPFFCMEA_03432	0.0	yjcD	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	DNA helicase
IPFFCMEA_03433	6.31e-51	-	-	-	-	-	-	-	-
IPFFCMEA_03434	2.22e-93	yjcF	-	-	S	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_03435	1.2e-121	yjcG	-	-	J	-	-	-	Belongs to the 2H phosphoesterase superfamily. YjcG family
IPFFCMEA_03436	1.63e-178	yjcH	-	-	P	ko:K07214	-	ko00000	COG2382 Enterochelin esterase and related enzymes
IPFFCMEA_03437	1.98e-273	metB	2.5.1.48	-	E	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IPFFCMEA_03438	1.84e-280	metC	4.4.1.8	-	E	ko:K01760	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000	cystathionine
IPFFCMEA_03439	2.79e-125	yjcK	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Alanine acetyltransferase
IPFFCMEA_03440	8.25e-271	yjcL	-	-	S	-	-	-	Protein of unknown function (DUF819)
IPFFCMEA_03442	1.71e-48	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPFFCMEA_03443	3.95e-23	int7	-	-	L	-	-	-	Belongs to the 'phage' integrase family
IPFFCMEA_03444	3.48e-43	xkdA	-	-	E	-	-	-	IrrE N-terminal-like domain
IPFFCMEA_03446	1.19e-42	-	-	-	S	-	-	-	Protein of unknown function (DUF4064)
IPFFCMEA_03447	5.33e-85	-	-	-	-	-	-	-	-
IPFFCMEA_03448	6.49e-58	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_03449	8.62e-21	-	-	-	K	-	-	-	Helix-turn-helix XRE-family like proteins
IPFFCMEA_03450	7.6e-12	-	-	-	S	-	-	-	Helix-turn-helix domain
IPFFCMEA_03451	2.09e-103	-	-	-	-	-	-	-	-
IPFFCMEA_03452	8.94e-317	yhdG	-	-	E	ko:K03294	-	ko00000	amino acid
IPFFCMEA_03453	2.89e-308	yhdH	-	-	S	ko:K03308	-	ko00000	Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IPFFCMEA_03454	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPFFCMEA_03455	1.75e-100	-	-	-	K	-	-	-	COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IPFFCMEA_03456	4.27e-59	yhdK	-	-	S	-	-	-	Sigma-M inhibitor protein
IPFFCMEA_03457	2.05e-256	yhdL	-	-	S	-	-	-	Sigma factor regulator N-terminal
IPFFCMEA_03458	3.24e-113	sigM	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_03459	1.12e-242	yhdN	-	-	C	-	-	-	Aldo keto reductase
IPFFCMEA_03460	3.9e-143	plsC	2.3.1.51	-	I	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01004	Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IPFFCMEA_03461	2.18e-304	yhdP	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPFFCMEA_03462	3.44e-97	cueR	-	-	K	ko:K11923	-	ko00000,ko03000	transcriptional
IPFFCMEA_03463	3.35e-92	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IPFFCMEA_03464	3.62e-171	yhdR	2.6.1.1	-	E	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko01000,ko01007	Aminotransferase
IPFFCMEA_03465	0.0	yhdT	-	-	P	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPFFCMEA_03466	2.48e-66	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPFFCMEA_03467	5.83e-87	crcB	-	-	D	ko:K06199	-	ko00000,ko02000	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IPFFCMEA_03468	9.03e-173	yhdW	3.1.4.46	-	C	ko:K01126	ko00564,map00564	ko00000,ko00001,ko01000	glycerophosphoryl diester phosphodiesterase
IPFFCMEA_03469	3.7e-09	yhdX	-	-	S	-	-	-	Uncharacterized protein YhdX
IPFFCMEA_03470	1.06e-258	yhdY	-	-	M	ko:K16052	-	ko00000,ko02000	Mechanosensitive ion channel
IPFFCMEA_03471	9.4e-177	cobB	-	-	K	ko:K12410	-	ko00000,ko01000	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IPFFCMEA_03472	9.72e-192	nodB1	-	-	G	-	-	-	deacetylase
IPFFCMEA_03473	2.6e-196	dat	2.6.1.21	-	E	ko:K00824	ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100	ko00000,ko00001,ko01000,ko01007	Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IPFFCMEA_03474	3.45e-301	nhaC	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IPFFCMEA_03475	1.53e-108	nhaX	-	-	T	-	-	-	Belongs to the universal stress protein A family
IPFFCMEA_03476	0.0	yheI	-	-	V	ko:K18216,ko:K18889	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPFFCMEA_03477	0.0	yheH	-	-	V	ko:K06147,ko:K18217,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko01504,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPFFCMEA_03478	1.29e-140	yheG	-	-	GM	-	-	-	NAD(P)H-binding
IPFFCMEA_03479	1.25e-38	sspB	-	-	S	ko:K06418,ko:K06419,ko:K06420	-	ko00000	spore protein
IPFFCMEA_03480	2.27e-49	yheE	-	-	S	-	-	-	Family of unknown function (DUF5342)
IPFFCMEA_03481	0.0	yheD	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IPFFCMEA_03482	2.77e-275	yheC	-	-	HJ	-	-	-	YheC/D like ATP-grasp
IPFFCMEA_03483	1.19e-258	yheB	-	-	S	-	-	-	Belongs to the UPF0754 family
IPFFCMEA_03484	7.46e-72	yheA	-	-	S	-	-	-	Belongs to the UPF0342 family
IPFFCMEA_03485	2.11e-131	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IPFFCMEA_03486	3.3e-92	yhaZ	-	-	L	-	-	-	DNA alkylation repair enzyme
IPFFCMEA_03487	8.7e-198	yhaX	-	-	S	-	-	-	haloacid dehalogenase-like hydrolase
IPFFCMEA_03488	0.0	hemZ	-	-	H	-	-	-	coproporphyrinogen III oxidase
IPFFCMEA_03489	4.36e-266	yhaU	-	-	P	ko:K03455	-	ko00000	COG0475 Kef-type K transport systems, membrane components
IPFFCMEA_03490	6.51e-114	-	-	-	P	ko:K07228	-	ko00000	regulatory, ligand-binding protein related to C-terminal domains of K channels
IPFFCMEA_03492	1.45e-170	yhaR	-	-	I	-	-	-	enoyl-CoA hydratase
IPFFCMEA_03493	1.89e-35	-	-	-	S	-	-	-	YhzD-like protein
IPFFCMEA_03494	5.56e-215	yhaQ	-	-	S	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_03495	5.14e-272	yhaP	-	-	CP	ko:K01992	-	ko00000,ko00002,ko02000	COG1668 ABC-type Na efflux pump, permease component
IPFFCMEA_03496	8.42e-302	yhaO	-	-	L	ko:K03547	-	ko00000,ko03400	DNA repair exonuclease
IPFFCMEA_03497	0.0	yhaN	-	-	L	-	-	-	AAA domain
IPFFCMEA_03498	5.22e-228	yhaM	-	-	L	ko:K03698	-	ko00000,ko01000,ko03019	Shows a 3'-5' exoribonuclease activity
IPFFCMEA_03499	1.88e-39	yhaL	-	-	S	-	-	-	Sporulation protein YhaL
IPFFCMEA_03500	4.7e-161	prsA	5.2.1.8	-	M	ko:K01802,ko:K07533	-	ko00000,ko01000,ko03110	plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IPFFCMEA_03501	5.71e-116	yhaK	-	-	S	-	-	-	Putative zincin peptidase
IPFFCMEA_03502	1.2e-72	yhaI	-	-	S	-	-	-	Protein of unknown function (DUF1878)
IPFFCMEA_03503	4.92e-148	hpr	-	-	K	ko:K09682	-	ko00000,ko03000	Negative regulator of protease production and sporulation
IPFFCMEA_03504	1.74e-54	yhaH	-	-	S	-	-	-	YtxH-like protein
IPFFCMEA_03505	3.36e-30	-	-	-	-	-	-	-	-
IPFFCMEA_03506	1.28e-103	trpP	-	-	S	-	-	-	Tryptophan transporter TrpP
IPFFCMEA_03507	1.84e-262	serC	2.6.1.52	-	E	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IPFFCMEA_03508	3.5e-106	hit	-	-	FG	ko:K02503	-	ko00000,ko04147	COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IPFFCMEA_03509	2.7e-176	ecsA	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	transporter (ATP-binding protein)
IPFFCMEA_03510	4.23e-270	ecsB	-	-	U	ko:K01992	-	ko00000,ko00002,ko02000	ABC transporter
IPFFCMEA_03511	2.89e-161	ecsC	-	-	S	-	-	-	EcsC protein family
IPFFCMEA_03512	1.27e-290	yhaA	-	-	E	ko:K01436	-	ko00000,ko01000,ko01002	COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IPFFCMEA_03513	2.7e-312	yhfA	-	-	C	-	-	-	membrane
IPFFCMEA_03514	1e-44	-	-	-	C	-	-	-	Rubrerythrin
IPFFCMEA_03515	1.31e-118	traP	1.14.99.57	-	S	ko:K21481	-	ko00000,ko01000	enzyme involved in biosynthesis of extracellular polysaccharides
IPFFCMEA_03516	0.0	pbpF	2.4.1.129, 3.4.16.4	GT51	M	ko:K12555	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IPFFCMEA_03517	1.24e-257	hemE	4.1.1.37	-	H	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IPFFCMEA_03518	3.28e-229	hemH	4.99.1.1, 4.99.1.9	-	H	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the ferrous insertion into protoporphyrin IX
IPFFCMEA_03519	0.0	hemY	1.3.3.15, 1.3.3.4	-	H	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IPFFCMEA_03520	6.76e-131	yhgD	-	-	K	ko:K09017	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_03521	0.0	yhgE	-	-	S	ko:K01421	-	ko00000	YhgE Pip N-terminal domain protein
IPFFCMEA_03522	1.96e-111	-	-	GH19	M	ko:K03791	-	ko00000	Lysin motif
IPFFCMEA_03523	2.61e-73	-	-	-	-	-	-	-	-
IPFFCMEA_03524	1.54e-269	purT	2.1.2.2	-	F	ko:K08289	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IPFFCMEA_03525	3.97e-227	mpr	-	-	M	-	-	-	Belongs to the peptidase S1B family
IPFFCMEA_03527	1.31e-212	-	-	-	S	-	-	-	Alpha/beta hydrolase family
IPFFCMEA_03528	6.9e-124	pssA	2.7.8.8	-	I	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IPFFCMEA_03529	7.07e-112	ybfM	-	-	S	-	-	-	SNARE associated Golgi protein
IPFFCMEA_03530	6.15e-190	psd	4.1.1.65	-	I	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IPFFCMEA_03531	2.25e-59	ybfN	-	-	-	-	-	-	-
IPFFCMEA_03532	0.0	-	-	-	S	ko:K06880	-	ko00000,ko01000,ko01504	Erythromycin esterase
IPFFCMEA_03533	5.14e-214	ybfP	-	-	K	ko:K13653	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_03534	2.35e-244	ybfQ	-	-	S	ko:K07146	-	ko00000	Belongs to the UPF0176 family
IPFFCMEA_03535	4.25e-273	gltP	-	-	C	ko:K11102	-	ko00000,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPFFCMEA_03536	0.0	ptsG	2.7.1.199	-	G	ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118	ko00010,ko00520,ko02060,map00010,map00520,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_03537	4.29e-174	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPFFCMEA_03538	2.91e-165	-	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IPFFCMEA_03540	1.25e-258	ilvE	2.6.1.42	-	E	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Branched-chain amino acid aminotransferase
IPFFCMEA_03541	2.51e-98	yneJ	-	-	O	-	-	-	COG4846 Membrane protein involved in cytochrome C biogenesis
IPFFCMEA_03542	7.38e-78	ccdB	-	-	T	ko:K03413	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	cheY-homologous receiver domain
IPFFCMEA_03543	4.13e-165	ccdA	-	-	O	ko:K06196	-	ko00000,ko02000	cytochrome c biogenesis protein
IPFFCMEA_03544	4.59e-21	ynzD	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IPFFCMEA_03545	4.36e-39	yneF	-	-	S	ko:K09976	-	ko00000	UPF0154 protein
IPFFCMEA_03546	2.18e-106	yneE	-	-	S	-	-	-	Sporulation inhibitor of replication protein sirA
IPFFCMEA_03547	0.0	tkt	2.2.1.1	-	G	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IPFFCMEA_03548	1.15e-43	ynzC	-	-	S	-	-	-	UPF0291 protein
IPFFCMEA_03549	5.4e-143	yneB	-	-	L	-	-	-	resolvase
IPFFCMEA_03550	8.5e-65	yneA	-	-	D	-	-	-	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IPFFCMEA_03551	7.22e-142	lexA	3.4.21.88	-	K	ko:K01356	-	ko00000,ko00002,ko01000,ko01002,ko03400	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPFFCMEA_03552	5.34e-97	fosB	-	-	H	ko:K11210,ko:K21252	-	ko00000,ko01000,ko01504	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IPFFCMEA_03553	1.75e-118	yndM	-	-	S	-	-	-	Protein of unknown function (DUF2512)
IPFFCMEA_03554	6.31e-173	yndL	-	-	S	-	-	-	Replication protein
IPFFCMEA_03557	0.0	yndJ	-	-	S	-	-	-	YndJ-like protein
IPFFCMEA_03558	2.87e-147	-	-	-	S	-	-	-	Domain of unknown function (DUF4166)
IPFFCMEA_03559	2.52e-196	yndG	-	-	S	-	-	-	DoxX-like family
IPFFCMEA_03560	5.45e-112	-	-	-	S	ko:K06293,ko:K06312	-	ko00000	Spore germination protein
IPFFCMEA_03561	1.82e-181	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IPFFCMEA_03562	9.36e-65	yndD1	-	-	EG	ko:K06288,ko:K06291,ko:K06310	-	ko00000	Spore germination protein
IPFFCMEA_03565	3.12e-104	yndB	-	-	S	-	-	-	Activator of Hsp90 ATPase homolog 1-like protein
IPFFCMEA_03566	8.92e-96	-	-	-	-	-	-	-	-
IPFFCMEA_03567	2.37e-34	tatA	-	-	U	ko:K03116,ko:K03117,ko:K03646	ko03060,ko03070,map03060,map03070	ko00000,ko00001,ko00002,ko02000,ko02044	protein secretion
IPFFCMEA_03570	2.43e-162	-	-	-	S	-	-	-	Domain of unknown function, YrpD
IPFFCMEA_03572	7.89e-210	thyA	2.1.1.45	-	F	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	ko00000,ko00001,ko00002,ko01000	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IPFFCMEA_03575	7.54e-22	-	-	-	-	-	-	-	-
IPFFCMEA_03576	1.22e-101	yncF	3.6.1.23	-	F	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	ko00000,ko00001,ko00002,ko01000,ko03400	Deoxyuridine 5'-triphosphate
IPFFCMEA_03578	4.34e-281	alr	5.1.1.1	-	E	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	ko00000,ko00001,ko01000,ko01011	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IPFFCMEA_03579	0.0	-	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPFFCMEA_03580	7.18e-145	yokF	3.1.31.1	-	L	ko:K01174	-	ko00000,ko01000	RNA catabolic process
IPFFCMEA_03582	3.72e-204	yhdF	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_03583	1.45e-258	citA	2.3.3.1	-	C	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	br01601,ko00000,ko00001,ko00002,ko01000	Belongs to the citrate synthase family
IPFFCMEA_03584	4.93e-210	citR	-	-	K	ko:K19242	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_03585	7.21e-204	lytE	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IPFFCMEA_03586	0.0	phoB	3.1.3.1	-	P	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	Belongs to the alkaline phosphatase family
IPFFCMEA_03587	0.0	spoVR	-	-	S	ko:K06415	-	ko00000	Stage V sporulation protein R
IPFFCMEA_03588	5.04e-305	ygxB	-	-	M	-	-	-	Conserved TM helix
IPFFCMEA_03589	3.38e-216	yhcP	-	-	-	-	-	-	-
IPFFCMEA_03590	7.05e-124	yhcQ	-	-	M	-	-	-	Spore coat protein
IPFFCMEA_03591	0.0	yhcR	3.1.3.5, 3.1.3.6, 3.1.4.16	-	F	ko:K01081,ko:K01119,ko:K08693	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IPFFCMEA_03592	1.25e-134	yhcS	3.4.22.70	-	M	ko:K07284	-	ko00000,ko01000,ko01002,ko01011	COG3764 Sortase (surface protein transpeptidase)
IPFFCMEA_03593	8.26e-219	rluA	5.4.99.23, 5.4.99.28, 5.4.99.29	-	J	ko:K06177,ko:K06180	-	ko00000,ko01000,ko03009,ko03016	Responsible for synthesis of pseudouridine from uracil
IPFFCMEA_03594	4.27e-89	yhcU	-	-	S	-	-	-	Family of unknown function (DUF5365)
IPFFCMEA_03595	7.16e-90	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IPFFCMEA_03596	1.24e-154	yhcW	-	-	S	ko:K07025	-	ko00000	hydrolase
IPFFCMEA_03597	0.0	yhcX	-	-	K	-	-	-	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IPFFCMEA_03598	0.0	yhxA	-	-	E	-	-	-	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IPFFCMEA_03599	5.35e-135	glpP	-	-	K	ko:K02443	-	ko00000,ko03000	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IPFFCMEA_03600	5.7e-196	glpF	-	-	G	ko:K02440	-	ko00000,ko02000	Belongs to the MIP aquaporin (TC 1.A.8) family
IPFFCMEA_03601	0.0	glpK	2.7.1.30	-	C	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	ko00000,ko00001,ko01000,ko04147	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IPFFCMEA_03602	0.0	glpD	1.1.3.21, 1.1.5.3	-	C	ko:K00105,ko:K00111	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IPFFCMEA_03603	0.0	pgcA	5.4.2.2	-	G	ko:K01835	ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoglucomutase
IPFFCMEA_03604	1.54e-271	yhcY	2.7.13.3	-	T	ko:K02480	-	ko00000,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_03605	9.41e-145	yhcZ	-	-	K	ko:K02479	-	ko00000,ko02022	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_03606	1.9e-115	yhdA	1.7.1.6	-	S	ko:K03206	-	ko00000,ko01000	NADPH-dependent FMN reductase
IPFFCMEA_03607	1.65e-51	yhdB	-	-	S	-	-	-	YhdB-like protein
IPFFCMEA_03608	1.02e-71	yhdC	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IPFFCMEA_03609	1.32e-272	lytF	-	CBM50	M	ko:K19220,ko:K19223,ko:K19224	-	ko00000,ko01000,ko01002,ko01011	COG1388 FOG LysM repeat
IPFFCMEA_03610	5.58e-99	nsrR	-	-	K	ko:K13771	ko05132,map05132	ko00000,ko00001,ko03000	Transcriptional regulator
IPFFCMEA_03611	3.35e-56	-	-	-	-	-	-	-	-
IPFFCMEA_03613	2.63e-264	yurR	1.4.5.1	-	E	ko:K00285	ko00360,map00360	ko00000,ko00001,ko01000	COG0665 Glycine D-amino acid oxidases (deaminating)
IPFFCMEA_03614	1.2e-87	yurQ	-	-	L	-	-	-	COG0322 Nuclease subunit of the excinuclease complex
IPFFCMEA_03615	9.11e-236	frlB	-	-	M	ko:K10708	-	ko00000,ko01000	Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IPFFCMEA_03616	2.46e-308	yurO	-	-	G	ko:K10117	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1653 ABC-type sugar transport system, periplasmic component
IPFFCMEA_03617	2.05e-198	yurN	-	-	G	ko:K10118	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPFFCMEA_03618	1.29e-89	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IPFFCMEA_03619	4.53e-107	-	-	-	P	ko:K10119	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0395 ABC-type sugar transport system, permease component
IPFFCMEA_03620	9.57e-209	-	2.7.1.218	-	G	ko:K10710	-	ko00000,ko01000	pfkB family carbohydrate kinase
IPFFCMEA_03621	8.71e-175	frlR1	-	-	K	ko:K03710,ko:K10711	-	ko00000,ko03000	UTRA
IPFFCMEA_03622	2.83e-261	msmX	-	-	P	ko:K10112	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Belongs to the ABC transporter superfamily
IPFFCMEA_03623	4.42e-216	bsn	-	-	L	-	-	-	Ribonuclease
IPFFCMEA_03624	4.82e-294	pucF	3.5.3.9	-	E	ko:K02083	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000,ko01002	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IPFFCMEA_03625	9.52e-303	pucG	2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51	-	E	ko:K00830,ko:K00839	ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146	ko00000,ko00001,ko00002,ko01000,ko01007	COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IPFFCMEA_03626	7.18e-234	pucA	1.17.1.4	-	O	ko:K00087,ko:K07402	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IPFFCMEA_03627	4.18e-141	pucB	1.17.1.4, 2.7.7.76	-	S	ko:K00087,ko:K07141	ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120	ko00000,ko00001,ko00002,ko01000	MobA-like NTP transferase domain
IPFFCMEA_03628	2.47e-187	pucC	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03519	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IPFFCMEA_03629	0.0	pucD	1.17.1.4	-	C	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IPFFCMEA_03630	1.7e-122	-	1.17.1.4, 1.2.5.3	-	C	ko:K00087,ko:K03518	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IPFFCMEA_03631	0.000154	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IPFFCMEA_03633	2.09e-72	pucM	3.5.2.17	-	S	ko:K07127	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000,ko02000	Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
IPFFCMEA_03634	0.0	-	1.7.3.3, 4.1.1.97	-	Q	ko:K16838	ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
IPFFCMEA_03635	4.37e-273	pbuX	-	-	F	ko:K16169,ko:K16170	-	ko00000,ko02000	xanthine
IPFFCMEA_03636	2.82e-298	pbuX	-	-	F	ko:K03458,ko:K16169,ko:K16170	-	ko00000,ko02000	Permease family
IPFFCMEA_03637	0.0	pucR	-	-	QT	ko:K09684	-	ko00000,ko03000	COG2508 Regulator of polyketide synthase expression
IPFFCMEA_03638	0.0	allB	3.5.2.5	-	F	ko:K01466	ko00230,ko01100,ko01120,map00230,map01100,map01120	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IPFFCMEA_03639	1.07e-79	yunG	-	-	-	-	-	-	-
IPFFCMEA_03640	4.26e-220	yunF	-	-	S	-	-	-	Protein of unknown function DUF72
IPFFCMEA_03641	7.59e-180	yunE	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IPFFCMEA_03642	0.0	yunD	3.1.3.5	-	F	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	ko00000,ko00001,ko01000	Belongs to the 5'-nucleotidase family
IPFFCMEA_03643	5.67e-64	yunC	-	-	S	-	-	-	Domain of unknown function (DUF1805)
IPFFCMEA_03644	3.49e-169	yunB	-	-	S	-	-	-	Sporulation protein YunB (Spo_YunB)
IPFFCMEA_03645	1.08e-251	lytH	-	-	M	ko:K21472	-	ko00000,ko01000,ko01002,ko01011	Peptidase, M23
IPFFCMEA_03646	1.37e-215	lipA	2.8.1.8	-	H	ko:K03644	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IPFFCMEA_03647	1.34e-144	yutC	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPFFCMEA_03648	3.2e-63	yutD	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03649	1.61e-97	yutE	-	-	S	-	-	-	Protein of unknown function DUF86
IPFFCMEA_03650	2.13e-182	nagD	3.1.3.41	-	G	ko:K01101	ko00627,ko01120,map00627,map01120	ko00000,ko00001,ko01000	Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IPFFCMEA_03651	3.34e-112	yutG	3.1.3.27	-	I	ko:K01095	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	COG1267 Phosphatidylglycerophosphatase A and related proteins
IPFFCMEA_03652	2.57e-252	yutH	-	-	S	-	-	-	Spore coat protein
IPFFCMEA_03653	6.79e-307	hom	1.1.1.3	-	E	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	homoserine dehydrogenase
IPFFCMEA_03654	9.76e-253	thrC	4.2.3.1	-	E	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IPFFCMEA_03655	2.99e-220	thrB	2.7.1.39	-	E	ko:K00872	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IPFFCMEA_03656	0.0	yuxL	3.4.19.1	-	EU	ko:K01303	-	ko00000,ko01000,ko01002	peptidase
IPFFCMEA_03657	1.26e-47	yutI	-	-	O	-	-	-	COG0694 Thioredoxin-like proteins and domains
IPFFCMEA_03658	5.44e-74	yuzD	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03659	1.12e-253	yutJ	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IPFFCMEA_03660	1.74e-52	yuzB	-	-	S	-	-	-	Belongs to the UPF0349 family
IPFFCMEA_03662	5.95e-306	srfAA	-	-	Q	ko:K15654,ko:K15655,ko:K16119	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_03663	9.65e-91	-	-	-	-	-	-	-	-
IPFFCMEA_03664	1.55e-215	fhuD	-	-	P	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_03665	5.95e-77	yxeA	-	-	S	-	-	-	Protein of unknown function (DUF1093)
IPFFCMEA_03666	0.0	yxdM	-	-	V	ko:K11636	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter (permease)
IPFFCMEA_03667	8.64e-178	yxdL	-	-	V	ko:K11635	ko02020,map02020	ko00000,ko00001,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_03668	1.75e-227	yxdK	2.7.13.3	-	T	ko:K11633	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_03669	9.37e-159	yxdJ	-	-	T	ko:K02483,ko:K11634	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IPFFCMEA_03670	3.3e-203	fbaA	4.1.2.13, 4.1.2.29	-	F	ko:K01624,ko:K03339	ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IPFFCMEA_03671	2.29e-193	iolI	5.3.99.11	-	G	ko:K06606	ko00562,ko01120,map00562,map01120	ko00000,ko00001,ko01000	Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IPFFCMEA_03672	1.08e-212	iolH	-	-	G	ko:K06605	-	ko00000	Xylose isomerase-like TIM barrel
IPFFCMEA_03673	4.44e-251	iolG	1.1.1.18, 1.1.1.369	-	S	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IPFFCMEA_03674	1.34e-294	iolF	-	-	EGP	ko:K06610	-	ko00000,ko02000	Major facilitator superfamily
IPFFCMEA_03675	4.99e-222	iolE	4.2.1.44	-	G	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IPFFCMEA_03676	0.0	iolD	3.7.1.22	-	E	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IPFFCMEA_03677	1.75e-227	iolC	2.7.1.92	-	G	ko:K03338	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IPFFCMEA_03678	2.43e-200	iolB	5.3.1.30	-	G	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	ko00000,ko00001,ko01000	Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IPFFCMEA_03679	0.0	iolA	1.2.1.18, 1.2.1.27	-	C	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IPFFCMEA_03680	1.56e-177	iolR	-	-	K	ko:K06608,ko:K11534	-	ko00000,ko03000	COG1349 Transcriptional regulators of sugar metabolism
IPFFCMEA_03681	2.04e-223	iolS	-	-	C	ko:K06607	-	ko00000,ko01000	Aldo keto reductase
IPFFCMEA_03682	7.27e-55	-	-	-	-	-	-	-	-
IPFFCMEA_03684	2.23e-17	-	-	-	S	-	-	-	CGNR zinc finger
IPFFCMEA_03685	1.05e-101	-	-	-	T	-	-	-	HPP family
IPFFCMEA_03686	2.22e-38	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPFFCMEA_03687	2.4e-233	csbC	-	-	U	ko:K02100,ko:K06609,ko:K08139	ko04113,map04113	ko00000,ko00001,ko02000	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
IPFFCMEA_03688	0.0	htpG	-	-	O	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	Molecular chaperone. Has ATPase activity
IPFFCMEA_03690	9.3e-23	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IPFFCMEA_03691	1.65e-155	yxbG	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IPFFCMEA_03692	6.97e-264	yxbF	-	-	K	-	-	-	Bacterial regulatory proteins, tetR family
IPFFCMEA_03693	3.42e-313	aldX	1.2.1.3	-	C	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the aldehyde dehydrogenase family
IPFFCMEA_03694	2.54e-43	yxaI	-	-	S	-	-	-	membrane protein domain
IPFFCMEA_03695	7.97e-83	-	-	-	S	-	-	-	Family of unknown function (DUF5391)
IPFFCMEA_03696	1.35e-97	yxaI	-	-	S	-	-	-	membrane protein domain
IPFFCMEA_03697	1.46e-283	-	-	-	P	ko:K07148	-	ko00000	Protein of unknown function (DUF418)
IPFFCMEA_03698	5.18e-251	-	1.13.11.24	-	S	ko:K07155	-	ko00000,ko01000	AraC-like ligand binding domain
IPFFCMEA_03699	1.12e-129	yxaF	-	-	K	ko:K18939	-	ko00000,ko00002,ko03000	Transcriptional regulator
IPFFCMEA_03700	2.49e-254	yxnA	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_03701	6.83e-94	-	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPFFCMEA_03702	2.53e-78	-	-	-	S	ko:K06518	-	ko00000,ko02000	LrgA family
IPFFCMEA_03703	2.19e-153	yxaC	-	-	M	-	-	-	effector of murein hydrolase
IPFFCMEA_03704	7.3e-245	-	-	-	GM	ko:K19426	-	ko00000,ko01000	Polysaccharide pyruvyl transferase
IPFFCMEA_03705	2e-264	glxK	2.7.1.165	-	G	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	ko00000,ko00001,ko01000	Belongs to the glycerate kinase type-1 family
IPFFCMEA_03706	1.27e-163	gntR	-	-	K	ko:K11476	-	ko00000,ko03000	transcriptional
IPFFCMEA_03707	0.0	gntK	2.7.1.12	-	G	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko01000	Belongs to the FGGY kinase family
IPFFCMEA_03708	1.18e-294	gntP	-	-	EG	ko:K03299	-	ko00000,ko02000	COG2610 H gluconate symporter and related permeases
IPFFCMEA_03709	0.0	gntZ	1.1.1.343, 1.1.1.44	-	G	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IPFFCMEA_03710	2.68e-135	ahpC	1.11.1.15	-	O	ko:K03386	ko04214,map04214	ko00000,ko00001,ko01000,ko04147	Alkyl hydroperoxide reductase
IPFFCMEA_03711	0.0	ahpF	-	-	O	ko:K03387	-	ko00000,ko01000	Alkyl hydroperoxide reductase
IPFFCMEA_03712	0.0	bglA	3.2.1.86	GT1	G	ko:K01223	ko00010,ko00500,map00010,map00500	ko00000,ko00001,ko01000	Belongs to the glycosyl hydrolase 1 family
IPFFCMEA_03713	4.15e-14	bglP	-	-	G	ko:K02755,ko:K02756,ko:K02757	ko02060,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	phosphotransferase system
IPFFCMEA_03714	1.95e-159	yydK	-	-	K	ko:K03489	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_03715	9.5e-153	-	-	-	S	ko:K16916	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC-2 family transporter protein
IPFFCMEA_03716	8.4e-143	-	-	-	P	ko:K16917	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	ABC transporter
IPFFCMEA_03717	0.0	fbp	3.1.3.11	-	G	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	ko00000,ko00001,ko00002,ko01000	Firmicute fructose-1,6-bisphosphatase
IPFFCMEA_03718	9.06e-47	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
IPFFCMEA_03719	1.66e-100	hsp	-	-	O	ko:K13993	ko04141,map04141	ko00000,ko00001,ko03110	Hsp20/alpha crystallin family
IPFFCMEA_03720	6.92e-17	cwlJ	3.5.1.28	-	M	ko:K01449	-	ko00000,ko01000	Cell wall
IPFFCMEA_03721	2.82e-122	yhjH	-	-	K	-	-	-	helix_turn_helix multiple antibiotic resistance protein
IPFFCMEA_03722	0.0	yhjG	-	-	CH	-	-	-	FAD binding domain
IPFFCMEA_03723	3.09e-118	spsB	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPFFCMEA_03724	2.82e-140	yhjE	-	-	S	-	-	-	SNARE associated Golgi protein
IPFFCMEA_03725	4.13e-78	yhjD	-	-	-	-	-	-	-
IPFFCMEA_03726	1.61e-36	yhjC	-	-	S	-	-	-	Protein of unknown function (DUF3311)
IPFFCMEA_03727	0.0	yhjB	-	-	E	ko:K03307	-	ko00000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPFFCMEA_03728	4.64e-53	yhjA	-	-	S	-	-	-	Excalibur calcium-binding domain
IPFFCMEA_03729	6.46e-210	yhxD	-	-	IQ	-	-	-	Enoyl-(Acyl carrier protein) reductase
IPFFCMEA_03730	2.19e-141	comK	-	-	K	ko:K02250	ko02024,map02024	ko00000,ko00001,ko02044,ko03000	Competence transcription factor
IPFFCMEA_03731	9.84e-45	yhzC	-	-	S	-	-	-	IDEAL
IPFFCMEA_03732	3.72e-202	yhxC	-	-	IQ	-	-	-	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_03733	3.74e-37	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IPFFCMEA_03734	4.28e-149	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IPFFCMEA_03735	1.18e-120	yhfW	-	-	CE	-	-	-	COG0665 Glycine D-amino acid oxidases (deaminating)
IPFFCMEA_03736	6.15e-259	hemAT	-	-	NT	ko:K06595	-	ko00000,ko02035	chemotaxis protein
IPFFCMEA_03737	1.47e-118	bioY	-	-	S	ko:K03523	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	BioY family
IPFFCMEA_03738	0.0	vraA	6.2.1.3	-	IQ	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IPFFCMEA_03739	6.04e-250	yhfS	2.3.1.9	-	I	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the thiolase family
IPFFCMEA_03740	9.64e-141	yhfR	5.4.2.12	-	G	ko:K15634,ko:K15640	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Belongs to the phosphoglycerate mutase family
IPFFCMEA_03741	9.92e-135	spoIIIAH	-	-	S	ko:K06397	-	ko00000	SpoIIIAH-like protein
IPFFCMEA_03742	7.6e-149	spoIIIAG	-	-	S	ko:K06396	-	ko00000	stage III sporulation protein AG
IPFFCMEA_03743	1.28e-131	spoIIIAF	-	-	S	ko:K06395	-	ko00000	Stage III sporulation protein AF (Spore_III_AF)
IPFFCMEA_03744	3.11e-256	spoIIIAE	-	-	S	ko:K06394	-	ko00000	stage III sporulation protein AE
IPFFCMEA_03745	1.93e-77	spoIIIAD	-	-	S	ko:K06393	-	ko00000	Stage III sporulation protein AD
IPFFCMEA_03746	1.63e-39	spoIIIAC	-	-	S	ko:K06392	-	ko00000	stage III sporulation protein AC
IPFFCMEA_03747	3.29e-110	spoIIIAB	-	-	S	ko:K06391	-	ko00000	Stage III sporulation protein
IPFFCMEA_03748	1.22e-218	spoIIIAA	-	-	S	ko:K06390	-	ko00000	stage III sporulation protein AA
IPFFCMEA_03749	6.96e-50	yqhV	-	-	S	-	-	-	Protein of unknown function (DUF2619)
IPFFCMEA_03750	4.8e-128	efp	-	-	J	ko:K02356	-	ko00000,ko03012	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPFFCMEA_03751	3.65e-250	yqhT	3.4.11.9, 3.4.13.9	-	E	ko:K01262,ko:K01271	-	ko00000,ko01000,ko01002	COG0006 Xaa-Pro aminopeptidase
IPFFCMEA_03752	1.17e-101	aroQ	4.2.1.10	-	E	ko:K03786	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a trans-dehydration via an enolate intermediate
IPFFCMEA_03753	8.02e-121	yqhR	-	-	S	-	-	-	Conserved membrane protein YqhR
IPFFCMEA_03754	1.48e-220	yqhQ	-	-	S	-	-	-	Protein of unknown function (DUF1385)
IPFFCMEA_03755	5.18e-81	yqhP	-	-	-	-	-	-	-
IPFFCMEA_03756	1.41e-209	yqhO	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IPFFCMEA_03757	1.97e-97	mntR	-	-	K	ko:K03709	-	ko00000,ko03000	Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IPFFCMEA_03758	2.63e-203	lipM	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IPFFCMEA_03759	2.51e-81	yqhL	-	-	P	-	-	-	COG0607 Rhodanese-related sulfurtransferase
IPFFCMEA_03760	0.0	gcvPB	1.4.4.2	-	E	ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPFFCMEA_03761	0.0	gcvPA	1.4.4.2	-	E	ko:K00282	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	ko00000,ko00001,ko01000	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IPFFCMEA_03762	7.79e-261	gcvT	2.1.2.10	-	E	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	ko00000,ko00001,ko00002,ko01000	The glycine cleavage system catalyzes the degradation of glycine
IPFFCMEA_03763	0.0	yqhH	-	-	L	-	-	-	COG0553 Superfamily II DNA RNA helicases, SNF2 family
IPFFCMEA_03764	1.52e-195	yqhG	-	-	S	-	-	-	Bacterial protein YqhG of unknown function
IPFFCMEA_03765	4.84e-34	sinI	-	-	S	ko:K06372	-	ko00000	Anti-repressor SinI
IPFFCMEA_03766	2.14e-71	sinR	-	-	K	ko:K19449	-	ko00000,ko03000	transcriptional
IPFFCMEA_03767	3.67e-181	tasA_1	-	-	S	ko:K06336	-	ko00000,ko01002	Cell division protein FtsN
IPFFCMEA_03768	4.27e-97	sipW	3.4.21.89	-	U	ko:K13280	ko03060,map03060	ko00000,ko00001,ko01000,ko01002	Signal peptidase
IPFFCMEA_03769	9.33e-155	yqxM	-	-	-	ko:K19433	-	ko00000	-
IPFFCMEA_03770	6.36e-71	yqzG	-	-	S	-	-	-	Protein of unknown function (DUF3889)
IPFFCMEA_03771	2.84e-36	yqzE	-	-	S	-	-	-	YqzE-like protein
IPFFCMEA_03772	3.78e-57	-	-	-	S	ko:K02249	-	ko00000,ko00002,ko02044	ComG operon protein 7
IPFFCMEA_03773	4.1e-60	comGF	-	-	U	ko:K02246,ko:K02248	-	ko00000,ko00002,ko02044	Putative Competence protein ComGF
IPFFCMEA_03774	3.45e-76	comGE	-	-	-	ko:K02247	-	ko00000,ko00002,ko02044	-
IPFFCMEA_03775	1.13e-92	gspH	-	-	NU	ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926	ko03070,ko05111,map03070,map05111	ko00000,ko00001,ko00002,ko02035,ko02044	protein transport across the cell outer membrane
IPFFCMEA_03776	5.33e-63	comGC	-	-	U	ko:K02245	-	ko00000,ko00002,ko02044	Required for transformation and DNA binding
IPFFCMEA_03777	7.16e-218	comGB	-	-	NU	ko:K02244	-	ko00000,ko00002,ko02044	COG1459 Type II secretory pathway, component PulF
IPFFCMEA_03778	9.05e-257	comGA	-	-	NU	ko:K02243	-	ko00000,ko00002,ko02044	COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPFFCMEA_03779	3.73e-09	yhcV	-	-	S	-	-	-	COG0517 FOG CBS domain
IPFFCMEA_03780	8.73e-233	yqxL	-	-	P	-	-	-	Mg2 transporter protein
IPFFCMEA_03781	2.01e-305	yqhB	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPFFCMEA_03782	4.82e-190	yqhA	-	-	T	ko:K17763	-	ko00000,ko03021	COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IPFFCMEA_03784	7.79e-85	yqgZ	1.20.4.1	-	P	ko:K00537,ko:K16509	-	ko00000,ko01000	Belongs to the ArsC family
IPFFCMEA_03785	1.46e-50	yqgY	-	-	S	-	-	-	Protein of unknown function (DUF2626)
IPFFCMEA_03787	4.72e-211	ctaA	-	-	O	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	ko00000,ko00001,ko00002,ko03029	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IPFFCMEA_03788	1.7e-208	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IPFFCMEA_03789	9.7e-252	ctaC	1.9.3.1	-	C	ko:K02275	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IPFFCMEA_03790	0.0	ctaD	1.9.3.1	-	C	ko:K02274	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IPFFCMEA_03791	1.84e-145	ctaE	1.9.3.1	-	C	ko:K02276	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IPFFCMEA_03792	1.75e-69	ctaF	1.9.3.1	-	C	ko:K02277	ko00190,ko01100,map00190,map01100	ko00000,ko00001,ko00002,ko01000	COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IPFFCMEA_03793	9.56e-211	ctaG	-	-	S	ko:K02862	-	ko00000	cytochrome c oxidase
IPFFCMEA_03794	1.61e-81	ylbA	-	-	S	-	-	-	YugN-like family
IPFFCMEA_03795	1.53e-97	ylbB	-	-	T	-	-	-	COG0517 FOG CBS domain
IPFFCMEA_03796	4.39e-256	ylbC	-	-	S	-	-	-	protein with SCP PR1 domains
IPFFCMEA_03797	3.78e-88	ylbD	-	-	S	-	-	-	Putative coat protein
IPFFCMEA_03798	1.73e-48	ylbE	-	-	S	-	-	-	YlbE-like protein
IPFFCMEA_03799	2.34e-97	ylbF	-	-	S	-	-	-	Belongs to the UPF0342 family
IPFFCMEA_03800	4.36e-52	ylbG	-	-	S	-	-	-	UPF0298 protein
IPFFCMEA_03801	1.43e-124	rsmD	2.1.1.171	-	L	ko:K08316	-	ko00000,ko01000,ko03009	Methyltransferase
IPFFCMEA_03802	3.8e-111	coaD	2.7.7.3	-	H	ko:K00954	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IPFFCMEA_03803	9.11e-281	ylbJ	-	-	S	-	-	-	Sporulation integral membrane protein YlbJ
IPFFCMEA_03804	2.56e-176	ylbK	-	-	S	ko:K07001	-	ko00000	esterase of the alpha-beta hydrolase superfamily
IPFFCMEA_03805	7.81e-239	ylbL	-	-	T	ko:K07177	ko02024,map02024	ko00000,ko00001,ko01002	Belongs to the peptidase S16 family
IPFFCMEA_03806	1.67e-291	ylbM	-	-	S	-	-	-	Belongs to the UPF0348 family
IPFFCMEA_03808	1.15e-115	ylbN	-	-	S	ko:K07040	-	ko00000	metal-binding, possibly nucleic acid-binding protein
IPFFCMEA_03809	1.71e-37	rpmF	-	-	J	ko:K02911	ko03010,map03010	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	Belongs to the bacterial ribosomal protein bL32 family
IPFFCMEA_03810	1.35e-106	ylbO	-	-	S	ko:K06314	-	ko00000,ko03000	SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IPFFCMEA_03811	1.33e-115	ylbP	-	-	K	-	-	-	n-acetyltransferase
IPFFCMEA_03812	3.22e-214	panE	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPFFCMEA_03813	0.0	bshC	-	-	S	ko:K22136	-	ko00000	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IPFFCMEA_03814	9.82e-102	mraZ	-	-	K	ko:K03925	-	ko00000	Belongs to the MraZ family
IPFFCMEA_03815	1.66e-218	rsmH	2.1.1.199	-	J	ko:K03438	-	ko00000,ko01000,ko03009	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IPFFCMEA_03816	3.42e-68	ftsL	-	-	D	-	-	-	Essential cell division protein
IPFFCMEA_03817	0.0	pbpX	-	-	M	ko:K08724,ko:K12552,ko:K12556	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IPFFCMEA_03818	0.0	spoVD	-	-	M	ko:K08384	ko00550,map00550	ko00000,ko00001,ko01011	stage V sporulation protein D
IPFFCMEA_03819	0.0	murE	6.3.2.13	-	M	ko:K01928	ko00300,ko00550,map00300,map00550	ko00000,ko00001,ko01000,ko01011	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPFFCMEA_03820	9.59e-220	mraY	2.7.8.13	-	M	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	ko00000,ko00001,ko01000,ko01011	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPFFCMEA_03821	0.0	murD	6.3.2.9	-	M	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPFFCMEA_03822	6.64e-237	spoVE	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IPFFCMEA_03823	3.15e-256	murG	2.4.1.227	GT28	M	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	ko00000,ko00001,ko01000,ko01011	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPFFCMEA_03824	1.3e-211	murB	1.3.1.98	-	M	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	ko00000,ko00001,ko01000,ko01011	cell wall formation
IPFFCMEA_03825	2.77e-177	divIB	-	-	D	ko:K03589	ko04112,map04112	ko00000,ko00001,ko03036	Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IPFFCMEA_03826	1.35e-143	ylxW	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03827	8.67e-132	ylxX	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_03828	5.37e-76	sbp	-	-	S	-	-	-	small basic protein
IPFFCMEA_03829	4.88e-299	ftsA	-	-	D	ko:K03590	ko04112,map04112	ko00000,ko00001,ko03036,ko04812	Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IPFFCMEA_03830	1.84e-260	ftsZ	-	-	D	ko:K03531	ko04112,map04112	ko00000,ko00001,ko02048,ko03036,ko04812	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPFFCMEA_03831	0.0	bpr	-	-	O	ko:K13276	-	ko00000,ko01000,ko01002,ko03110	COG1404 Subtilisin-like serine proteases
IPFFCMEA_03833	3.49e-219	spoIIGA	-	-	M	ko:K06383	-	ko00000,ko01000,ko01002	aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IPFFCMEA_03834	1.48e-160	sigE	-	-	K	ko:K03091	-	ko00000,ko03021	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_03835	6.57e-179	sigG	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_03836	6.37e-188	ylmA	3.6.3.34	-	P	ko:K02013	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IPFFCMEA_03837	0.0	argE	-	-	E	ko:K20895	ko00730,ko01100,map00730,map01100	ko00000,ko00001,ko01000	Acetylornithine deacetylase
IPFFCMEA_03838	4.19e-50	ylmC	-	-	S	-	-	-	sporulation protein
IPFFCMEA_03839	7.53e-203	ylmD	-	-	S	ko:K05810	-	ko00000,ko01000	Belongs to the multicopper oxidase YfiH RL5 family
IPFFCMEA_03840	3.15e-162	ylmE	-	-	S	ko:K06997	-	ko00000	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IPFFCMEA_03841	5.44e-88	sepF	-	-	D	ko:K09772	-	ko00000,ko03036	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IPFFCMEA_03842	1.74e-53	ylmG	-	-	S	ko:K02221	-	ko00000,ko02044	membrane
IPFFCMEA_03843	2.03e-176	ylmH	-	-	S	-	-	-	conserved protein, contains S4-like domain
IPFFCMEA_03844	6.44e-100	divIVA	-	-	D	ko:K04074	-	ko00000,ko03036	Cell division initiation protein
IPFFCMEA_03845	0.0	ileS	6.1.1.5	-	J	ko:K01870	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPFFCMEA_03846	5.89e-230	yaaC	-	-	S	-	-	-	YaaC-like Protein
IPFFCMEA_03847	0.0	guaB	1.1.1.205	-	F	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko04147	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IPFFCMEA_03848	3.75e-316	dacA	3.4.16.4	-	M	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IPFFCMEA_03849	3.7e-202	pdxS	4.3.3.6	-	H	ko:K06215	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IPFFCMEA_03850	5.55e-137	pdxT	4.3.3.6	-	H	ko:K08681	ko00750,map00750	ko00000,ko00001,ko01000	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IPFFCMEA_03851	4.64e-294	serS	6.1.1.11	-	J	ko:K01875	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPFFCMEA_03853	3.72e-159	dck	2.7.1.74, 2.7.1.76	-	F	ko:K15519	ko00230,ko00240,ko01100,map00230,map00240,map01100	ko00000,ko00001,ko01000	Deoxycytidine kinase
IPFFCMEA_03854	5.73e-149	dgk	2.7.1.113	-	F	ko:K15518	ko00230,map00230	ko00000,ko00001,ko01000	Deoxyguanosine kinase
IPFFCMEA_03855	7.55e-271	yaaH	-	-	M	ko:K06306	-	ko00000	Glycoside Hydrolase Family
IPFFCMEA_03856	5.64e-125	yaaI	-	-	Q	-	-	-	COG1335 Amidases related to nicotinamidase
IPFFCMEA_03857	1.05e-108	tadA	3.5.4.33	-	FJ	ko:K11991	-	ko00000,ko01000,ko03016	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IPFFCMEA_03858	0.0	dnaX	2.7.7.7	-	L	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPFFCMEA_03859	8.75e-55	yaaK	-	-	S	ko:K09747	-	ko00000	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPFFCMEA_03860	8.53e-142	recR	-	-	L	ko:K06187	ko03440,map03440	ko00000,ko00001,ko03400	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPFFCMEA_03861	1.55e-42	yaaL	-	-	S	-	-	-	Protein of unknown function (DUF2508)
IPFFCMEA_03862	5.3e-49	bofA	-	-	S	ko:K06317	-	ko00000	Sigma-K factor-processing regulatory protein BofA
IPFFCMEA_03863	8.04e-188	nadK2	2.7.1.23	-	G	ko:K00858	ko00760,ko01100,map00760,map01100	ko00000,ko00001,ko01000	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IPFFCMEA_03864	3.25e-228	sppA	-	-	OU	ko:K04773	-	ko00000,ko01000,ko01002	signal peptide peptidase SppA
IPFFCMEA_03865	8.23e-112	yteJ	-	-	S	-	-	-	RDD family
IPFFCMEA_03866	6.29e-144	ytfI	-	-	S	-	-	-	Protein of unknown function (DUF2953)
IPFFCMEA_03867	5.02e-90	ytfJ	-	-	S	-	-	-	Sporulation protein YtfJ
IPFFCMEA_03868	1.93e-116	tpx	1.11.1.15	-	O	ko:K11065	-	ko00000,ko01000	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IPFFCMEA_03869	6.26e-223	ytxK	2.1.1.72	-	L	ko:K00571	-	ko00000,ko01000,ko02048	DNA methylase
IPFFCMEA_03870	4.69e-281	ackA	2.7.2.1	-	F	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IPFFCMEA_03871	3.31e-114	moaB	2.7.7.75	-	H	ko:K03638	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	May be involved in the biosynthesis of molybdopterin
IPFFCMEA_03872	1.06e-297	argG	6.3.4.5	-	E	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	ko00000,ko00001,ko00002,ko01000,ko04147	Belongs to the argininosuccinate synthase family. Type 1 subfamily
IPFFCMEA_03873	0.0	argH	4.3.2.1	-	E	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000,ko04147	argininosuccinate lyase
IPFFCMEA_03875	8.04e-182	ytkK	1.1.1.100	-	IQ	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_03876	1.91e-166	ytkL	-	-	S	-	-	-	Belongs to the UPF0173 family
IPFFCMEA_03877	1.13e-308	ytoI	-	-	K	-	-	-	transcriptional regulator containing CBS domains
IPFFCMEA_03878	2.15e-63	ytpI	-	-	S	-	-	-	YtpI-like protein
IPFFCMEA_03879	1.24e-230	nrnA	3.1.13.3, 3.1.3.7	-	S	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	ko00000,ko00001,ko01000,ko03400	COG0618 Exopolyphosphatase-related proteins
IPFFCMEA_03880	1.15e-39	-	-	-	-	-	-	-	-
IPFFCMEA_03881	5.12e-112	ytrI	-	-	-	-	-	-	-
IPFFCMEA_03882	2.45e-75	ytrH	-	-	S	-	-	-	Sporulation protein YtrH
IPFFCMEA_03883	0.0	dnaE	2.7.7.7	-	L	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	DNA polymerase
IPFFCMEA_03884	1.21e-286	ytsJ	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	Malate dehydrogenase
IPFFCMEA_03885	5.1e-207	accD	2.1.3.15, 6.4.1.2	-	I	ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IPFFCMEA_03886	9.82e-234	accA	2.1.3.15, 6.4.1.2	-	I	ko:K01962	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	ko00000,ko00001,ko00002,ko01000	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IPFFCMEA_03887	4.65e-229	pfkA	2.7.1.11	-	F	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IPFFCMEA_03888	0.0	pyk	2.7.1.40	-	G	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	Belongs to the pyruvate kinase family
IPFFCMEA_03889	2.71e-81	fxsA	-	-	S	ko:K07113	-	ko00000	COG3030 Protein affecting phage T7 exclusion by the F plasmid
IPFFCMEA_03890	2.24e-244	ytvI	-	-	S	-	-	-	sporulation integral membrane protein YtvI
IPFFCMEA_03891	9.38e-95	ytwI	-	-	S	-	-	-	membrane
IPFFCMEA_03892	3.21e-305	-	-	-	L	-	-	-	COG3328 Transposase and inactivated derivatives
IPFFCMEA_03893	3.86e-10	-	-	-	S	-	-	-	Family of unknown function (DUF5316)
IPFFCMEA_03895	8.21e-15	-	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03896	2.07e-303	pepS	-	-	E	ko:K19689	-	ko00000,ko01000,ko01002	COG2309 Leucyl aminopeptidase (aminopeptidase T)
IPFFCMEA_03897	1.09e-18	-	-	-	S	-	-	-	Uncharacterized protein YkpC
IPFFCMEA_03898	8.77e-234	mreBH	-	-	D	ko:K03569	-	ko00000,ko02048,ko03036,ko04812	Rod-share determining protein MreBH
IPFFCMEA_03899	2.63e-58	abrB	-	-	K	ko:K06284	-	ko00000,ko03000	of stationary sporulation gene expression
IPFFCMEA_03900	0.0	yhfL	6.2.1.3	-	IQ	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	AMP-binding enzyme C-terminal domain
IPFFCMEA_03901	1.01e-141	yhfK	-	-	GM	-	-	-	NmrA-like family
IPFFCMEA_03902	4.06e-245	lplJ	6.3.1.20	-	H	ko:K03800	ko00785,ko01100,map00785,map01100	ko00000,ko00001,ko01000	Lipoate-protein ligase
IPFFCMEA_03903	1.63e-180	yhfI	-	-	S	-	-	-	COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IPFFCMEA_03904	4.77e-289	gltT	-	-	C	ko:K03309,ko:K11102,ko:K11103	ko02020,map02020	ko00000,ko00001,ko02000	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IPFFCMEA_03905	1.79e-92	-	-	-	S	-	-	-	ASCH
IPFFCMEA_03906	1.55e-252	yhfE	-	-	G	-	-	-	peptidase M42
IPFFCMEA_03907	3.8e-177	yhfC	-	-	S	-	-	-	Putative membrane peptidase family (DUF2324)
IPFFCMEA_03908	1.77e-236	fabHB	2.3.1.180	-	I	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	ko00000,ko00001,ko00002,ko01000,ko01004	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IPFFCMEA_03909	1.62e-307	acm2	3.2.1.17	-	NU	ko:K01185	-	ko00000,ko01000	Prophage endopeptidase tail
IPFFCMEA_03910	1.96e-141	-	-	-	S	-	-	-	Phage tail protein
IPFFCMEA_03911	0.0	-	-	-	S	-	-	-	peptidoglycan catabolic process
IPFFCMEA_03912	4.09e-16	-	-	-	-	-	-	-	-
IPFFCMEA_03913	1.58e-36	-	-	-	-	-	-	-	-
IPFFCMEA_03914	9.75e-79	-	-	-	-	-	-	-	-
IPFFCMEA_03915	1.42e-40	-	-	-	-	-	-	-	-
IPFFCMEA_03916	1.54e-62	-	-	-	S	-	-	-	Bacteriophage HK97-gp10, putative tail-component
IPFFCMEA_03917	1.23e-32	-	-	-	S	-	-	-	Phage gp6-like head-tail connector protein
IPFFCMEA_03918	1.23e-39	-	-	-	S	-	-	-	peptidoglycan catabolic process
IPFFCMEA_03919	8.02e-09	-	-	-	S	-	-	-	peptidoglycan catabolic process
IPFFCMEA_03920	3.43e-227	-	-	-	S	-	-	-	capsid protein
IPFFCMEA_03921	9.36e-135	-	-	-	S	-	-	-	peptidase activity
IPFFCMEA_03922	4.77e-273	-	-	-	S	-	-	-	Phage portal protein
IPFFCMEA_03923	2.58e-14	-	-	-	-	-	-	-	-
IPFFCMEA_03924	1.6e-276	-	-	-	S	-	-	-	Phage Terminase
IPFFCMEA_03925	1e-89	-	-	-	S	-	-	-	Phage terminase, small subunit
IPFFCMEA_03926	2.63e-11	-	-	-	-	-	-	-	-
IPFFCMEA_03929	0.000711	-	-	-	-	-	-	-	-
IPFFCMEA_03930	1.63e-09	-	-	-	-	-	-	-	-
IPFFCMEA_03931	6.99e-09	-	-	-	S	ko:K09167	-	ko00000	Bacterial PH domain
IPFFCMEA_03932	1.88e-51	ydbT	-	-	S	ko:K08981	-	ko00000	Bacterial PH domain
IPFFCMEA_03934	1.36e-37	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPFFCMEA_03935	2.02e-48	dinB2	-	-	L	ko:K03502	-	ko00000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPFFCMEA_03936	4.84e-85	-	-	-	S	-	-	-	damaged DNA binding
IPFFCMEA_03937	2.34e-14	-	-	-	S	-	-	-	YolD-like protein
IPFFCMEA_03940	1.06e-127	-	-	-	J	-	-	-	Acetyltransferase (GNAT) domain
IPFFCMEA_03941	7.01e-129	yokK	-	-	S	-	-	-	SMI1 / KNR4 family
IPFFCMEA_03942	3.18e-101	-	-	-	S	-	-	-	SMI1-KNR4 cell-wall
IPFFCMEA_03943	1.35e-111	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IPFFCMEA_03944	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPFFCMEA_03945	2.8e-132	yokH	-	-	G	-	-	-	SMI1 / KNR4 family
IPFFCMEA_03946	0.0	iaaM	1.4.3.4	-	E	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	ko00000,ko00001,ko00002,ko01000	COG1231 Monoamine oxidase
IPFFCMEA_03947	9e-72	csaA	-	-	J	ko:K06878	-	ko00000	tRNA-binding protein
IPFFCMEA_03948	5.45e-173	yobQ	-	-	K	-	-	-	helix_turn_helix, arabinose operon control protein
IPFFCMEA_03949	2.81e-178	-	-	-	J	-	-	-	FR47-like protein
IPFFCMEA_03950	6.23e-127	yobS	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_03951	1.29e-167	yobT	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPFFCMEA_03952	4.8e-111	-	-	-	K	-	-	-	Bacterial transcription activator, effector binding domain
IPFFCMEA_03953	1.73e-221	yobV	-	-	K	-	-	-	WYL domain
IPFFCMEA_03954	7.38e-121	yobW	-	-	-	-	-	-	-
IPFFCMEA_03955	8.12e-69	czrA	-	-	K	ko:K22043	-	ko00000,ko03000	transcriptional
IPFFCMEA_03956	3.28e-157	yocA	-	-	M	-	-	-	COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IPFFCMEA_03957	9.04e-156	ybbM	-	-	S	ko:K02069	-	ko00000,ko00002,ko02000	transport system, permease component
IPFFCMEA_03958	2.79e-175	yjkB	-	-	P	ko:K02068	-	ko00000,ko00002,ko02000	ATPases associated with a variety of cellular activities
IPFFCMEA_03959	8.95e-225	yjlA	-	-	EG	-	-	-	Putative multidrug resistance efflux transporter
IPFFCMEA_03960	1.26e-20	yjlB	-	-	S	-	-	-	Cupin domain
IPFFCMEA_03961	4.85e-54	yjlB	-	-	S	-	-	-	Cupin domain
IPFFCMEA_03962	1.39e-87	yjlC	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IPFFCMEA_03963	2.15e-280	yjlD	1.6.99.3	-	C	ko:K03885	ko00190,map00190	ko00000,ko00001,ko01000	NADH dehydrogenase
IPFFCMEA_03964	0.0	uxaC	5.3.1.12	-	G	ko:K01812	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	glucuronate isomerase
IPFFCMEA_03965	1.13e-165	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IPFFCMEA_03966	8.14e-128	-	-	-	G	ko:K03292	-	ko00000	symporter YjmB
IPFFCMEA_03967	1.03e-241	allD	1.1.1.350	-	C	ko:K00073	ko00230,ko01120,map00230,map01120	ko00000,ko00001,ko01000	Belongs to the LDH2 MDH2 oxidoreductase family
IPFFCMEA_03968	1.53e-244	yjmD	1.1.1.380	-	E	ko:K08322	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko01000	Alcohol dehydrogenase GroES-like domain
IPFFCMEA_03969	1.08e-270	uxuA	4.2.1.8	-	G	ko:K01686	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the dehydration of D-mannonate
IPFFCMEA_03970	1.83e-194	yjmF	-	-	IQ	-	-	-	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_03971	4.58e-288	exuT	-	-	G	ko:K03535,ko:K08191	-	ko00000,ko02000	Sugar (and other) transporter
IPFFCMEA_03972	1.15e-236	exuR	-	-	K	ko:K02529	-	ko00000,ko03000	transcriptional
IPFFCMEA_03973	0.0	uxaB	1.1.1.58	-	G	ko:K00041	ko00040,ko01100,map00040,map01100	ko00000,ko00001,ko00002,ko01000	tagaturonate reductase activity
IPFFCMEA_03974	0.0	uxaA	4.2.1.42, 4.2.1.7	-	G	ko:K01685,ko:K01708	ko00040,ko00053,ko01100,map00040,map00053,map01100	ko00000,ko00001,ko00002,ko01000	Altronate
IPFFCMEA_03975	4.56e-167	yjnA	-	-	S	ko:K07090	-	ko00000	membrane transporter protein
IPFFCMEA_03981	2.54e-53	nucA	-	-	M	-	-	-	Deoxyribonuclease NucA/NucB
IPFFCMEA_03982	3.45e-158	-	-	-	L	-	-	-	TIGRFAM Transposase, IS605 OrfB, C-terminal
IPFFCMEA_03984	2.66e-120	yebE	-	-	S	-	-	-	UPF0316 protein
IPFFCMEA_03985	3.13e-38	yebG	-	-	S	-	-	-	NETI protein
IPFFCMEA_03986	2.28e-108	purE	5.4.99.18	-	F	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IPFFCMEA_03987	1.24e-276	purK	6.3.4.18	-	F	ko:K01589	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IPFFCMEA_03988	6.85e-315	purB	4.3.2.2	-	F	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IPFFCMEA_03989	5.86e-168	purC	6.3.2.6	-	F	ko:K01923	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the SAICAR synthetase family
IPFFCMEA_03990	3.79e-52	purS	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPFFCMEA_03991	1.15e-167	purQ	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPFFCMEA_03992	0.0	purL	6.3.5.3	-	F	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IPFFCMEA_03993	0.0	purF	2.4.2.14	-	F	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPFFCMEA_03994	9.88e-240	purM	6.3.3.1	-	F	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Phosphoribosylformylglycinamidine cyclo-ligase
IPFFCMEA_03995	3.62e-137	purN	2.1.2.2	-	F	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IPFFCMEA_03996	0.0	purH	2.1.2.3, 3.5.4.10	-	F	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	ko00000,ko00001,ko00002,ko01000,ko04147	Bifunctional purine biosynthesis protein PurH
IPFFCMEA_03997	5.45e-296	purD	6.3.4.13	-	F	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Belongs to the GARS family
IPFFCMEA_03998	7.5e-92	-	-	-	K	-	-	-	helix_turn_helix ASNC type
IPFFCMEA_03999	1.49e-240	-	-	-	E	ko:K16263	-	ko00000,ko02000	Amino acid permease
IPFFCMEA_04000	3.45e-37	-	-	-	S	-	-	-	Protein of unknown function (DUF2892)
IPFFCMEA_04001	0.0	yerA	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	adenine deaminase
IPFFCMEA_04002	9.58e-244	yerB	-	-	S	-	-	-	Protein of unknown function (DUF3048) C-terminal domain
IPFFCMEA_04003	6.27e-67	yerC	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_04004	0.0	yerD	1.4.7.1	-	E	ko:K00284	ko00630,ko00910,ko01120,map00630,map00910,map01120	ko00000,ko00001,ko01000	Belongs to the glutamate synthase family
IPFFCMEA_04006	5.63e-157	pcrB	-	-	I	ko:K07094	-	ko00000,ko01000	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IPFFCMEA_04007	0.0	pcrA	3.6.4.12	-	L	ko:K03657	ko03420,ko03430,map03420,map03430	ko00000,ko00001,ko01000,ko03400	ATP-dependent DNA helicase
IPFFCMEA_04008	0.0	ligA	6.5.1.2	-	L	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	ko00000,ko00001,ko01000,ko03032,ko03400	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPFFCMEA_04009	1.77e-281	camS	-	-	S	-	-	-	COG4851 Protein involved in sex pheromone biosynthesis
IPFFCMEA_04010	2.45e-250	yerI	-	-	S	-	-	-	homoserine kinase type II (protein kinase fold)
IPFFCMEA_04011	2.29e-160	sapB	-	-	S	ko:K07507	-	ko00000,ko02000	MgtC SapB transporter
IPFFCMEA_04012	0.0	putP	-	-	E	ko:K03307,ko:K11928	-	ko00000,ko02000	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPFFCMEA_04013	7.37e-61	gatC	6.3.5.6, 6.3.5.7	-	J	ko:K02435	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPFFCMEA_04014	0.0	gatA	6.3.5.6, 6.3.5.7	-	J	ko:K02433	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IPFFCMEA_04015	0.0	gatB	6.3.5.6, 6.3.5.7	-	J	ko:K02434	ko00970,ko01100,map00970,map01100	ko00000,ko00001,ko01000,ko03029	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPFFCMEA_04016	2.08e-190	yerO	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04017	0.0	swrC	-	-	V	ko:K03296	-	ko00000	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IPFFCMEA_04018	1.8e-218	dagK	2.7.1.107	-	I	ko:K07029	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	ko00000,ko00001,ko01000	COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IPFFCMEA_04019	0.0	rlmCD	2.1.1.190	-	J	ko:K03215	-	ko00000,ko01000,ko03009	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IPFFCMEA_04020	0.0	-	-	-	L	-	-	-	Type III restriction enzyme res subunit
IPFFCMEA_04024	1.59e-124	rapA	-	-	S	ko:K06359,ko:K06360,ko:K06367	ko02024,map02024	ko00000,ko00001,ko01000	Response regulator aspartate phosphatase
IPFFCMEA_04026	5.1e-36	-	-	-	-	-	-	-	-
IPFFCMEA_04027	3.39e-98	-	-	-	S	-	-	-	Protein of unknown function, DUF600
IPFFCMEA_04028	0.0	-	-	-	L	-	-	-	nucleic acid phosphodiester bond hydrolysis
IPFFCMEA_04030	2.44e-127	-	-	-	L	-	-	-	endonuclease activity
IPFFCMEA_04031	1.23e-14	-	-	-	S	-	-	-	Pfam:DUF1311
IPFFCMEA_04032	4.97e-271	rapH	-	-	S	ko:K06366	ko02024,map02024	ko00000,ko00001,ko01000	Tetratricopeptide repeat
IPFFCMEA_04034	6.29e-162	yeeN	-	-	K	-	-	-	transcriptional regulatory protein
IPFFCMEA_04036	7.28e-132	dhaR3	-	-	K	ko:K16137	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_04037	4.59e-101	yesE	-	-	S	ko:K06893	-	ko00000	SnoaL-like domain
IPFFCMEA_04038	1.87e-192	yesF	-	-	GM	-	-	-	NAD(P)H-binding
IPFFCMEA_04039	3.8e-60	cotJA	-	-	S	ko:K06332	-	ko00000	Spore coat associated protein JA (CotJA)
IPFFCMEA_04040	2.31e-61	cotJB	-	-	S	ko:K06333	-	ko00000	CotJB protein
IPFFCMEA_04041	6.05e-133	cotJC	-	-	P	ko:K06334	-	ko00000	Spore Coat
IPFFCMEA_04042	1.19e-130	yesJ	-	-	K	-	-	-	Acetyltransferase (GNAT) family
IPFFCMEA_04043	2.56e-132	yesL	-	-	S	-	-	-	Protein of unknown function, DUF624
IPFFCMEA_04044	0.0	yesM	2.7.13.3	-	T	ko:K07718	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_04045	7.1e-163	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IPFFCMEA_04046	1.32e-69	-	-	-	K	ko:K07720	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	helix_turn_helix, arabinose operon control protein
IPFFCMEA_04047	6.85e-313	yesO	-	-	G	ko:K02027	-	ko00000,ko00002,ko02000	Bacterial extracellular solute-binding protein
IPFFCMEA_04048	6.98e-77	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPFFCMEA_04049	3.57e-120	yesP	-	-	G	ko:K02025	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPFFCMEA_04050	8.84e-211	-	-	-	P	ko:K02026	-	ko00000,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPFFCMEA_04051	8e-254	-	3.2.1.172	GH105	S	ko:K15532	-	ko00000,ko01000	Glycosyl Hydrolase Family 88
IPFFCMEA_04052	0.0	yesS	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04053	5.05e-171	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPFFCMEA_04054	1.07e-164	yesU	-	-	S	-	-	-	Domain of unknown function (DUF1961)
IPFFCMEA_04055	4.69e-144	-	-	-	S	-	-	-	Protein of unknown function, DUF624
IPFFCMEA_04056	0.0	-	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IPFFCMEA_04057	0.0	yesX	4.2.2.23, 4.2.2.24	PL11	E	ko:K18197,ko:K18198	-	ko00000,ko01000	cell wall organization
IPFFCMEA_04058	7.51e-159	-	-	-	E	-	-	-	GDSL-like Lipase/Acylhydrolase
IPFFCMEA_04059	0.0	-	3.2.1.23	-	G	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	ko00000,ko00001,ko01000	beta-galactosidase activity
IPFFCMEA_04060	2.25e-127	yetA	-	-	-	-	-	-	-
IPFFCMEA_04061	0.0	yetA	-	-	-	-	-	-	-
IPFFCMEA_04062	0.0	lplA	-	-	G	ko:K17318	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Bacterial extracellular solute-binding protein
IPFFCMEA_04063	1.18e-226	lplB	-	-	G	ko:K17319	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG4209 ABC-type polysaccharide transport system, permease component
IPFFCMEA_04064	7.85e-209	-	-	-	G	ko:K17320	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Binding-protein-dependent transport system inner membrane component
IPFFCMEA_04065	0.0	-	3.2.1.22	-	G	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	ko00000,ko00001,ko01000	Family 4 glycosyl hydrolase
IPFFCMEA_04066	3.66e-157	yetF	-	-	S	-	-	-	membrane
IPFFCMEA_04067	1.57e-71	yetG	1.14.99.48	-	S	ko:K07145	ko00860,ko01110,map00860,map01110	ko00000,ko00001,ko01000	Antibiotic biosynthesis monooxygenase
IPFFCMEA_04068	2.47e-85	yetH	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPFFCMEA_04072	3.5e-269	glcP	-	-	G	ko:K08174	-	ko00000,ko02000	Major Facilitator Superfamily
IPFFCMEA_04073	9.38e-256	-	1.1.1.18, 1.1.1.361, 1.1.1.369	-	S	ko:K00010,ko:K18652	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	ko00000,ko00001,ko01000	Oxidoreductase family, C-terminal alpha/beta domain
IPFFCMEA_04074	8.81e-204	ntdB	3.1.3.24, 3.1.3.92	-	S	ko:K07024,ko:K18654	ko00500,map00500	ko00000,ko00001,ko01000	Sucrose-6F-phosphate phosphohydrolase
IPFFCMEA_04075	0.0	-	2.6.1.104	-	E	ko:K18653	-	ko00000,ko01000	Belongs to the DegT DnrJ EryC1 family
IPFFCMEA_04076	5.09e-238	yhjM	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04077	5.04e-259	yhjN	-	-	S	ko:K07120	-	ko00000	membrane
IPFFCMEA_04078	1.36e-267	-	-	-	EGP	-	-	-	Transmembrane secretion effector
IPFFCMEA_04079	0.0	-	-	-	S	-	-	-	Sugar transport-related sRNA regulator N-term
IPFFCMEA_04080	6.29e-100	yhjR	-	-	S	-	-	-	Rubrerythrin
IPFFCMEA_04081	0.0	rexB	3.6.4.12	-	L	ko:K16899	-	ko00000,ko01000,ko03400	ATP-dependent helicase deoxyribonuclease subunit B
IPFFCMEA_04082	0.0	addA	3.6.4.12	-	L	ko:K16898	-	ko00000,ko01000,ko03400	ATP-dependent helicase nuclease subunit A
IPFFCMEA_04083	3.84e-278	sbcD	-	-	L	ko:K03547	-	ko00000,ko03400	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IPFFCMEA_04084	0.0	sbcC	-	-	L	ko:K03546	-	ko00000,ko03400	COG0419 ATPase involved in DNA repair
IPFFCMEA_04085	7.78e-66	yisB	-	-	V	-	-	-	COG1403 Restriction endonuclease
IPFFCMEA_04086	3.3e-43	gerPF	-	-	S	ko:K06299,ko:K06304	-	ko00000	Spore germination protein gerPA/gerPF
IPFFCMEA_04087	4.08e-88	gerPE	-	-	S	ko:K06303	-	ko00000	Spore germination protein GerPE
IPFFCMEA_04088	1.49e-33	gerPD	-	-	S	ko:K06302	-	ko00000	Spore germination protein
IPFFCMEA_04089	1e-93	gerPC	-	-	S	ko:K06301	-	ko00000	Spore germination protein
IPFFCMEA_04090	1.02e-46	gerPB	-	-	S	ko:K06300	-	ko00000	cell differentiation
IPFFCMEA_04091	7.41e-45	gerPA	-	-	S	ko:K06299	-	ko00000	Spore germination protein
IPFFCMEA_04092	1.52e-32	yisI	-	-	S	-	-	-	Spo0E like sporulation regulatory protein
IPFFCMEA_04093	1.88e-222	cotH	-	-	M	ko:K06330	-	ko00000	Spore Coat
IPFFCMEA_04094	3.11e-218	yisK	-	-	Q	-	-	-	COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IPFFCMEA_04095	1.02e-74	yisL	-	-	S	-	-	-	UPF0344 protein
IPFFCMEA_04096	0.0	wprA	-	-	O	ko:K13274	-	ko00000,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPFFCMEA_04098	1.8e-177	gmT1	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPFFCMEA_04099	2.44e-210	-	-	-	K	-	-	-	AraC-like ligand binding domain
IPFFCMEA_04100	2.27e-220	ydeD	-	-	EG	-	-	-	COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IPFFCMEA_04101	7.62e-210	ydeE	-	-	K	ko:K13653	-	ko00000,ko03000	AraC family transcriptional regulator
IPFFCMEA_04102	0.0	-	-	-	K	-	-	-	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPFFCMEA_04103	1.34e-196	ydeG	-	-	EGP	-	-	-	Major facilitator superfamily
IPFFCMEA_04104	4.72e-134	ydeI	-	-	S	-	-	-	Bacteriocin-protection, YdeI or OmpD-Associated
IPFFCMEA_04105	0.0	argS	6.1.1.19	-	J	ko:K01887	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	Arginyl-tRNA synthetase
IPFFCMEA_04106	5.42e-95	ywiB	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_04107	3.71e-12	-	-	-	S	-	-	-	Bacteriocin subtilosin A
IPFFCMEA_04108	0.0	-	-	-	C	ko:K22227	-	ko00000	Fe-S oxidoreductases
IPFFCMEA_04110	5.02e-168	-	-	-	V	ko:K01990	-	ko00000,ko00002,ko02000	ABC transporter
IPFFCMEA_04111	1.81e-292	mgtA	3.6.3.2	-	P	ko:K01531,ko:K16905	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	ATPase, P-type transporting, HAD superfamily, subfamily IC
IPFFCMEA_04112	3.84e-273	-	2.7.1.26, 2.7.7.2	-	L	ko:K07263,ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	ko00000,ko00001,ko00002,ko01000,ko01002	Peptidase, M16
IPFFCMEA_04113	1.17e-315	-	-	-	L	-	-	-	Peptidase, M16
IPFFCMEA_04115	1.31e-303	ywhL	-	-	CO	-	-	-	amine dehydrogenase activity
IPFFCMEA_04116	1.57e-96	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IPFFCMEA_04117	1.72e-156	ywhK	-	-	CO	-	-	-	amine dehydrogenase activity
IPFFCMEA_04118	3.28e-99	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPFFCMEA_04120	2.76e-65	-	-	-	S	-	-	-	Aminoacyl-tRNA editing domain
IPFFCMEA_04121	2.1e-215	speB	3.5.3.11	-	E	ko:K01480	ko00330,ko01100,map00330,map01100	ko00000,ko00001,ko00002,ko01000	Belongs to the arginase family
IPFFCMEA_04122	1.93e-204	speE	2.5.1.16	-	E	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IPFFCMEA_04123	0.0	pbpG	2.4.1.129, 3.4.16.4	GT51	M	ko:K21464	ko00550,map00550	ko00000,ko00001,ko01000,ko01003,ko01011	penicillin-binding protein
IPFFCMEA_04124	2.1e-64	-	-	-	-	-	-	-	-
IPFFCMEA_04125	1.92e-123	ywhD	-	-	S	-	-	-	YwhD family
IPFFCMEA_04126	3.29e-154	ywhC	-	-	S	-	-	-	Peptidase family M50
IPFFCMEA_04127	1.43e-35	dmpI	5.3.2.6	-	G	ko:K01821	ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220	ko00000,ko00001,ko00002,ko01000	4-oxalocrotonate tautomerase
IPFFCMEA_04128	1.45e-93	ywhA	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04129	0.0	thrS	6.1.1.3	-	J	ko:K01868	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPFFCMEA_04131	1.54e-306	mmr	-	-	U	ko:K08166	-	ko00000,ko02000	Major Facilitator Superfamily
IPFFCMEA_04132	1.1e-103	yffB	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04133	1.47e-115	ywgA	-	-	-	ko:K09388	-	ko00000	-
IPFFCMEA_04134	0.0	ywfO	-	-	S	ko:K06885	-	ko00000	COG1078 HD superfamily phosphohydrolases
IPFFCMEA_04135	8.55e-49	ywzC	-	-	S	-	-	-	Belongs to the UPF0741 family
IPFFCMEA_04136	6.58e-146	rsfA_1	-	-	-	ko:K06314	-	ko00000,ko03000	-
IPFFCMEA_04137	5.88e-200	ywfM	-	-	EG	ko:K03298	-	ko00000,ko02000	EamA-like transporter family
IPFFCMEA_04138	4.16e-197	lipL	2.3.1.200, 2.3.1.204	-	H	ko:K16869,ko:K18821	-	ko00000,ko01000	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IPFFCMEA_04139	3.73e-209	cysL	-	-	K	ko:K21900	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_04140	1.67e-224	pta	2.3.1.8, 3.6.3.21	-	C	ko:K00625,ko:K02028	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	ko00000,ko00001,ko00002,ko01000,ko02000	In Salmonella this enzyme is required for ethanolamine catabolism
IPFFCMEA_04141	1.4e-186	ywfI	-	-	C	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	ko00000,ko00001,ko01000	May function as heme-dependent peroxidase
IPFFCMEA_04142	1.95e-175	ywfH	-	-	IQ	ko:K19550	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Enoyl-(Acyl carrier protein) reductase
IPFFCMEA_04143	3.03e-294	ywfG	-	-	E	ko:K08969,ko:K19549	ko00270,ko01100,ko01130,map00270,map01100,map01130	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase class I and II
IPFFCMEA_04144	3.21e-267	bacE	-	-	EGP	ko:K19552	-	ko00000,ko02000	Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
IPFFCMEA_04145	0.0	bacD	6.3.2.49	-	F	ko:K13037	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IPFFCMEA_04146	1.33e-179	bacC	1.1.1.385	-	IQ	ko:K19548	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_04147	1.24e-175	bacB	5.3.3.19	-	S	ko:K19547	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IPFFCMEA_04148	5.11e-146	bacA	4.1.1.100	-	E	ko:K19546	ko01130,map01130	ko00000,ko00001,ko00002,ko01000	Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IPFFCMEA_04149	7.27e-26	-	-	-	K	-	-	-	Cro/C1-type HTH DNA-binding domain
IPFFCMEA_04151	4.71e-122	rok	-	-	K	-	-	-	Repressor of ComK
IPFFCMEA_04152	4.23e-104	ykuV	-	-	CO	-	-	-	thiol-disulfide
IPFFCMEA_04153	9.78e-130	ykuU	-	-	O	-	-	-	Alkyl hydroperoxide reductase
IPFFCMEA_04154	4.1e-181	ykuT	-	-	M	ko:K22044	-	ko00000,ko02000	Mechanosensitive ion channel
IPFFCMEA_04155	7.23e-51	ykuS	-	-	S	-	-	-	Belongs to the UPF0180 family
IPFFCMEA_04156	4.43e-273	hipO	3.5.1.47	-	E	ko:K05823	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01002	Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IPFFCMEA_04157	1.31e-125	dapH	2.3.1.117, 2.3.1.89	-	E	ko:K00674,ko:K05822	ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IPFFCMEA_04158	2.95e-101	fld	-	-	C	ko:K03839	-	ko00000	Flavodoxin
IPFFCMEA_04159	1.74e-222	ykuO	-	-	-	-	-	-	-
IPFFCMEA_04160	6.35e-113	-	-	-	C	ko:K03839	-	ko00000	Flavodoxin domain
IPFFCMEA_04161	7.61e-215	ccpC	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04162	6.01e-99	ykuL	-	-	S	-	-	-	CBS domain
IPFFCMEA_04163	7.83e-38	ykzF	-	-	S	-	-	-	Antirepressor AbbA
IPFFCMEA_04164	6.44e-122	-	-	-	S	ko:K09776	-	ko00000	Ribonuclease H-like
IPFFCMEA_04165	5.16e-50	ykuJ	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_04166	1.76e-298	ykuI	-	-	T	-	-	-	Diguanylate phosphodiesterase
IPFFCMEA_04167	2.6e-182	fadH	1.3.1.34	-	IQ	ko:K00219	-	ko00000,ko01000	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IPFFCMEA_04168	1.42e-211	ykuE	-	-	S	ko:K07098	-	ko00000	Metallophosphoesterase
IPFFCMEA_04169	5.84e-115	ykuD	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_04170	2.55e-305	ykuC	-	-	EGP	-	-	-	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_04171	3.71e-110	ykyB	-	-	S	-	-	-	YkyB-like protein
IPFFCMEA_04172	4.95e-216	cheV	-	-	T	ko:K03408,ko:K03415	ko02020,ko02030,map02020,map02030	ko00000,ko00001,ko00002,ko02022,ko02035	Chemotaxis protein CheV
IPFFCMEA_04173	1.05e-22	-	-	-	-	-	-	-	-
IPFFCMEA_04174	1.78e-284	patA	-	-	E	ko:K00841	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	ko00000,ko00001,ko00002,ko01000,ko01007	Aminotransferase
IPFFCMEA_04175	0.0	kinA	2.7.13.3	-	T	ko:K02491	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_04176	0.0	pbp2b	-	-	M	ko:K00687,ko:K12553,ko:K21465,ko:K21466	ko00550,ko01100,ko01501,map00550,map01100,map01501	ko00000,ko00001,ko01000,ko01011	Penicillin-binding Protein
IPFFCMEA_04177	8.32e-151	ykwD	-	-	J	-	-	-	protein with SCP PR1 domains
IPFFCMEA_04179	3.1e-75	-	-	-	L	ko:K07491	-	ko00000	transposase IS200-family protein
IPFFCMEA_04180	4.27e-114	-	-	-	S	-	-	-	Fic/DOC family
IPFFCMEA_04182	1.55e-187	rapA1	-	-	S	ko:K06359,ko:K06361	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPFFCMEA_04183	3.97e-69	-	-	-	L	-	-	-	transposase, IS605 OrfB family
IPFFCMEA_04184	4.95e-140	-	-	-	-	-	-	-	-
IPFFCMEA_04185	2.4e-41	-	-	-	S	-	-	-	SNARE associated Golgi protein
IPFFCMEA_04186	3.3e-19	ptsH	-	-	G	ko:K11189	-	ko00000,ko02000	PTS HPr component phosphorylation site
IPFFCMEA_04187	2.44e-110	-	-	-	K	-	-	-	Transcriptional regulator C-terminal region
IPFFCMEA_04188	4.66e-197	ydeK	-	-	EG	-	-	-	-transporter
IPFFCMEA_04189	0.0	ydeL	-	-	K	ko:K00375	-	ko00000,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPFFCMEA_04190	2.49e-95	ydeM1	-	-	I	-	-	-	N-terminal half of MaoC dehydratase
IPFFCMEA_04191	1.37e-134	-	-	-	S	ko:K07002	-	ko00000	Serine hydrolase
IPFFCMEA_04192	1.02e-72	-	-	-	K	-	-	-	HxlR-like helix-turn-helix
IPFFCMEA_04193	9.32e-194	ydeO	-	-	S	-	-	-	Uncharacterized protein conserved in bacteria (DUF2179)
IPFFCMEA_04194	3e-75	arsR	-	-	K	ko:K03892,ko:K22043	-	ko00000,ko03000	transcriptional
IPFFCMEA_04195	1.75e-294	arsB	-	-	P	ko:K03893	-	ko00000,ko02000	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IPFFCMEA_04196	8.66e-186	-	-	-	J	-	-	-	GNAT acetyltransferase
IPFFCMEA_04197	9.99e-197	-	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_04198	0.0	ydfD	-	-	K	ko:K18907	-	ko00000,ko00002,ko01504,ko03000	COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IPFFCMEA_04199	1.54e-232	-	4.1.1.86	-	E	ko:K13745	ko00260,ko01120,map00260,map01120	ko00000,ko00001,ko01000	Pyridoxal-dependent decarboxylase conserved domain
IPFFCMEA_04200	4.04e-149	ydfE	-	-	S	-	-	-	Flavin reductase like domain
IPFFCMEA_04201	5.24e-159	ydfF	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IPFFCMEA_04202	1.15e-20	-	-	-	S	-	-	-	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IPFFCMEA_04204	3.75e-249	ydfH	2.7.13.3	-	T	ko:K11623	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	Histidine kinase
IPFFCMEA_04205	1.55e-140	ydfI	-	-	K	ko:K11624	ko02020,map02020	ko00000,ko00001,ko00002,ko02022	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IPFFCMEA_04206	0.0	ydfJ	-	-	S	ko:K06994,ko:K11625	ko02020,map02020	ko00000,ko00001	drug exporters of the RND superfamily
IPFFCMEA_04207	1.96e-302	srfAB	-	-	Q	ko:K15654,ko:K15655,ko:K16120	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IPFFCMEA_04208	0.0	srfAC	-	-	Q	ko:K15656,ko:K16121	ko01054,ko02024,map01054,map02024	ko00000,ko00001,ko01008	COG1020 Non-ribosomal peptide synthetase modules and related proteins
IPFFCMEA_04209	1.63e-179	srfAD	-	-	Q	ko:K15657	ko02024,map02024	ko00000,ko00001,ko01008	thioesterase
IPFFCMEA_04210	4.92e-285	-	-	-	EGP	-	-	-	Major Facilitator Superfamily
IPFFCMEA_04211	1.48e-122	-	-	-	S	-	-	-	YcxB-like protein
IPFFCMEA_04212	1.17e-198	ycxC	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_04213	0.0	ycxD	-	-	K	-	-	-	GntR family transcriptional regulator
IPFFCMEA_04214	8.24e-146	sfp	-	-	H	ko:K06133	ko00770,map00770	ko00000,ko00001,ko01000	Belongs to the P-Pant transferase superfamily
IPFFCMEA_04215	6.13e-148	yczE	-	-	S	ko:K07149	-	ko00000	membrane
IPFFCMEA_04216	7.11e-172	tcyC	-	-	E	ko:K10010	ko02010,map02010	ko00000,ko00001,ko00002,ko01000,ko02000	COG1126 ABC-type polar amino acid transport system, ATPase component
IPFFCMEA_04217	4.6e-157	tcyB	-	-	P	ko:K10009	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG0765 ABC-type amino acid transport system, permease component
IPFFCMEA_04218	4.3e-188	tcyA	-	-	ET	ko:K02424	ko02010,map02010	ko00000,ko00001,ko00002,ko02000,ko02035	Belongs to the bacterial solute-binding protein 3 family
IPFFCMEA_04219	1.25e-207	yclA	-	-	K	ko:K21755	-	ko00000,ko03000	LysR substrate binding domain
IPFFCMEA_04220	2.24e-140	ubiX	2.5.1.129	-	H	ko:K03186	ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IPFFCMEA_04221	0.0	yclC	4.1.1.61, 4.1.1.98	-	H	ko:K01612,ko:K03182,ko:K16874	ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220	ko00000,ko00001,ko00002,ko01000	Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IPFFCMEA_04222	4.02e-52	-	4.1.1.61	-	S	ko:K21759	ko00627,ko01120,ko01220,map00627,map01120,map01220	ko00000,ko00001,ko01000	response to toxic substance
IPFFCMEA_04223	6.45e-55	yclD	-	-	-	-	-	-	-
IPFFCMEA_04224	6.42e-201	yclE	3.4.11.5	-	S	ko:K01259	ko00330,map00330	ko00000,ko00001,ko01000,ko01002	Alpha beta hydrolase
IPFFCMEA_04225	0.0	dtpT	-	-	E	ko:K03305	-	ko00000	amino acid peptide transporter
IPFFCMEA_04226	0.0	yclG	-	-	M	-	-	-	Pectate lyase superfamily protein
IPFFCMEA_04227	2.17e-118	-	2.3.1.128	-	J	ko:K03790	-	ko00000,ko01000,ko03009	Acetyltransferase (GNAT) domain
IPFFCMEA_04229	9.69e-104	ebsC	-	-	S	ko:K03976	-	ko00000,ko01000,ko03016	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IPFFCMEA_04230	6.12e-40	-	-	-	S	-	-	-	Domain of unknown function (DUF4177)
IPFFCMEA_04231	2.7e-68	yjdJ	-	-	S	-	-	-	Domain of unknown function (DUF4306)
IPFFCMEA_04232	8.79e-223	ctaB	2.5.1.141	-	O	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IPFFCMEA_04234	0.0	yjeA	3.5.1.104	-	G	ko:K22278	-	ko00000,ko01000	Polysaccharide deacetylase
IPFFCMEA_04235	9.03e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF2690)
IPFFCMEA_04236	1.13e-29	yjfB	-	-	S	-	-	-	Putative motility protein
IPFFCMEA_04237	1.93e-62	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IPFFCMEA_04238	3.15e-136	yjfC	-	-	O	-	-	-	Predicted Zn-dependent protease (DUF2268)
IPFFCMEA_04239	2.8e-89	yjgA	-	-	T	-	-	-	Protein of unknown function (DUF2809)
IPFFCMEA_04240	4.08e-132	yjgB	-	-	S	-	-	-	Domain of unknown function (DUF4309)
IPFFCMEA_04241	0.0	yjgC	1.17.1.9	-	C	ko:K00123	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	ko00000,ko00001,ko01000	formate dehydrogenase (NAD+) activity
IPFFCMEA_04242	5.25e-113	yjgD	-	-	S	-	-	-	Protein of unknown function (DUF1641)
IPFFCMEA_04244	8.38e-144	yjhB	3.6.1.13	-	F	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	ADP-ribose pyrophosphatase
IPFFCMEA_04246	4.06e-287	yjiB	1.14.14.46, 1.14.15.13	-	C	ko:K15468,ko:K16593,ko:K17474	ko00780,ko01100,map00780,map01100	ko00000,ko00001,ko00002,ko00199,ko01000,ko01008	Cytochrome P450
IPFFCMEA_04247	1.76e-279	yjiC	-	-	CG	-	-	-	COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IPFFCMEA_04248	1.11e-41	-	-	-	-	-	-	-	-
IPFFCMEA_04249	5.02e-188	hemD	4.2.1.75	-	H	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	ko00000,ko00001,ko00002,ko01000	Uroporphyrinogen-III synthase
IPFFCMEA_04250	2.73e-28	xhlB	-	-	S	-	-	-	SPP1 phage holin
IPFFCMEA_04251	3.63e-43	-	-	-	K	-	-	-	sigma factor activity
IPFFCMEA_04252	2.88e-185	ybfI	-	-	K	-	-	-	AraC-like ligand binding domain
IPFFCMEA_04253	5.01e-133	ybfH	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_04254	1.59e-65	-	-	-	L	-	-	-	Transposase
IPFFCMEA_04255	3.23e-222	yhfQ	-	-	M	ko:K02016	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	Periplasmic binding protein
IPFFCMEA_04256	2.4e-232	yhfP	1.1.1.1	-	C	ko:K00001	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	ko00000,ko00001,ko01000	Quinone oxidoreductase
IPFFCMEA_04257	5.98e-100	-	-	-	K	-	-	-	acetyltransferase
IPFFCMEA_04258	6.91e-260	aprE	3.4.21.62	-	O	ko:K01342,ko:K13277	ko02024,map02024	ko00000,ko00001,ko01000,ko01002,ko03110	Belongs to the peptidase S8 family
IPFFCMEA_04259	9.64e-308	yhfN	-	-	O	-	-	-	Peptidase M48
IPFFCMEA_04260	7.65e-83	yhfM	-	-	-	-	-	-	-
IPFFCMEA_04261	3.29e-104	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IPFFCMEA_04262	4.49e-136	rapK	-	-	S	ko:K06369	ko02024,map02024	ko00000,ko00001,ko01000	aspartate phosphatase
IPFFCMEA_04266	9.33e-108	-	-	-	S	-	-	-	Protein of unknown function (DUF3800)
IPFFCMEA_04267	8.64e-97	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPFFCMEA_04268	4.66e-41	ppiB	5.2.1.8	-	O	ko:K03768	-	ko00000,ko01000,ko03110	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IPFFCMEA_04269	3.12e-192	ypuA	-	-	S	-	-	-	Secreted protein
IPFFCMEA_04270	0.0	lysA	4.1.1.20	-	E	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IPFFCMEA_04271	0.0	spoVAF	-	-	EG	ko:K06408	-	ko00000	Stage V sporulation protein AF
IPFFCMEA_04272	1.85e-143	-	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IPFFCMEA_04273	2.15e-75	spoVAEB	-	-	S	ko:K06407	-	ko00000	stage V sporulation protein
IPFFCMEA_04274	8.55e-246	spoVAD	-	-	I	ko:K06406	-	ko00000	Stage V sporulation protein AD
IPFFCMEA_04275	6.71e-102	spoVAC	-	-	S	ko:K06405	-	ko00000	stage V sporulation protein AC
IPFFCMEA_04276	5.43e-90	spoVAB	-	-	S	ko:K06404	-	ko00000	Stage V sporulation protein AB
IPFFCMEA_04277	4.7e-143	spoVAA	-	-	S	ko:K06403	-	ko00000	Stage V sporulation protein AA
IPFFCMEA_04278	1.18e-174	sigF	-	-	K	ko:K03091	-	ko00000,ko03021	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPFFCMEA_04279	6.78e-100	spoIIAB	2.7.11.1	-	F	ko:K06379	-	ko00000,ko01000	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IPFFCMEA_04280	1.98e-76	spoIIAA	-	-	T	ko:K06378	-	ko00000	Belongs to the anti-sigma-factor antagonist family
IPFFCMEA_04281	8.27e-272	dacF	3.4.16.4	-	M	ko:K07258	ko00550,ko01100,map00550,map01100	ko00000,ko00001,ko01000,ko01002,ko01011	Belongs to the peptidase S11 family
IPFFCMEA_04282	1.39e-190	punA	2.4.2.1, 2.4.2.28	-	F	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	ko00000,ko00001,ko00002,ko01000	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IPFFCMEA_04283	3.77e-291	deoB	5.4.2.7	-	G	ko:K01839	ko00030,ko00230,map00030,map00230	ko00000,ko00001,ko01000	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IPFFCMEA_04284	2.26e-213	xerD	-	-	L	ko:K04763	-	ko00000,ko03036	recombinase XerD
IPFFCMEA_04285	2.73e-50	-	-	-	S	-	-	-	Protein of unknown function (DUF4227)
IPFFCMEA_04286	2.26e-104	fur	-	-	P	ko:K03711	-	ko00000,ko03000	Belongs to the Fur family
IPFFCMEA_04287	1.96e-139	spoIIM	-	-	S	ko:K06384	-	ko00000	Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IPFFCMEA_04288	1.47e-41	yqkK	-	-	-	-	-	-	-
IPFFCMEA_04289	3.95e-309	mleA	1.1.1.38	-	C	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	ko00000,ko00001,ko01000	malic enzyme
IPFFCMEA_04290	0.0	mleN	-	-	C	ko:K03315	-	ko00000,ko02000	Na H antiporter
IPFFCMEA_04291	0.0	aspA	4.3.1.1	-	E	ko:K01744	ko00250,ko01100,map00250,map01100	ko00000,ko00001,ko01000	Aspartate ammonia-lyase
IPFFCMEA_04292	1.77e-238	ansA	3.5.1.1	-	EJ	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	ko00000,ko00001,ko01000	L-asparaginase
IPFFCMEA_04293	3.18e-77	ansR	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04294	1.45e-280	yqxK	-	-	L	-	-	-	DNA helicase
IPFFCMEA_04295	4.07e-120	nudF	3.6.1.13	-	L	ko:K01515	ko00230,map00230	ko00000,ko00001,ko01000	Belongs to the Nudix hydrolase family
IPFFCMEA_04296	6.19e-09	-	-	-	S	-	-	-	Protein of unknown function (DUF3936)
IPFFCMEA_04297	2.09e-214	yqkF	-	-	C	-	-	-	oxidoreductases (related to aryl-alcohol dehydrogenases)
IPFFCMEA_04298	8.04e-27	yqkE	-	-	S	-	-	-	Protein of unknown function (DUF3886)
IPFFCMEA_04299	4.61e-222	yqkD	-	-	S	ko:K06889	-	ko00000	COG1073 Hydrolases of the alpha beta superfamily
IPFFCMEA_04300	1.12e-53	yqkC	-	-	S	-	-	-	Protein of unknown function (DUF2552)
IPFFCMEA_04301	6.17e-73	yqkB	-	-	S	-	-	-	Belongs to the HesB IscA family
IPFFCMEA_04302	3.23e-248	yqkA	-	-	K	-	-	-	GrpB protein
IPFFCMEA_04303	1.52e-76	yqjZ	-	-	S	-	-	-	enzyme involved in biosynthesis of extracellular polysaccharides
IPFFCMEA_04304	5.46e-113	yqjY	-	-	K	ko:K06977	-	ko00000	acetyltransferase
IPFFCMEA_04305	1.87e-65	yqiX	-	-	S	-	-	-	YolD-like protein
IPFFCMEA_04306	1.46e-304	polYB	2.7.7.7	-	L	ko:K02346,ko:K03502	-	ko00000,ko01000,ko03400	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPFFCMEA_04308	4.23e-287	yqjV	-	-	G	-	-	-	Major Facilitator Superfamily
IPFFCMEA_04310	2.21e-94	yqjT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPFFCMEA_04311	2.69e-228	coaA	2.7.1.33	-	F	ko:K00867	ko00770,ko01100,map00770,map01100	ko00000,ko00001,ko00002,ko01000	Pantothenic acid kinase
IPFFCMEA_04312	0.0	dsdA	4.3.1.18	-	E	ko:K01753	ko00260,map00260	ko00000,ko00001,ko01000	Belongs to the serine threonine dehydratase family. DsdA subfamily
IPFFCMEA_04313	6.89e-185	yqjQ	-	-	S	ko:K07124	-	ko00000	Belongs to the short-chain dehydrogenases reductases (SDR) family
IPFFCMEA_04314	1.56e-227	yqjP	-	-	S	-	-	-	COG0491 Zn-dependent hydrolases, including glyoxylases
IPFFCMEA_04315	1.96e-189	proC	1.5.1.2	-	E	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IPFFCMEA_04316	4.78e-152	-	-	-	L	-	-	-	Bacterial dnaA protein
IPFFCMEA_04317	6.98e-279	-	-	-	L	-	-	-	Transposase
IPFFCMEA_04318	2e-169	-	-	-	-	-	-	-	-
IPFFCMEA_04319	5.85e-164	-	-	-	-	-	-	-	-
IPFFCMEA_04320	0.0	miaB	2.8.4.3	-	J	ko:K06168	-	ko00000,ko01000,ko03016	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPFFCMEA_04321	1.27e-89	ymcA	3.6.3.21	-	S	ko:K02028	-	ko00000,ko00002,ko01000,ko02000	Belongs to the UPF0342 family
IPFFCMEA_04322	1.74e-119	cotE	-	-	S	ko:K06328	-	ko00000	Spore coat protein
IPFFCMEA_04323	0.0	mutS	-	-	L	ko:K03555	ko03430,map03430	ko00000,ko00001,ko03400	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPFFCMEA_04324	0.0	mutL	-	-	L	ko:K03572	ko03430,map03430	ko00000,ko00001,ko03400	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IPFFCMEA_04329	5.52e-31	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IPFFCMEA_04330	5.89e-58	-	-	-	L	-	-	-	Phage integrase family
IPFFCMEA_04337	0.0	pabB	2.6.1.85	-	EH	ko:K01665	ko00790,map00790	ko00000,ko00001,ko01000	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IPFFCMEA_04338	2.44e-136	pabA	2.6.1.85	-	EH	ko:K01664	ko00790,map00790	ko00000,ko00001,ko01000	Anthranilate synthase
IPFFCMEA_04339	2.09e-212	pabC	4.1.3.38	-	EH	ko:K02619	ko00790,map00790	ko00000,ko00001,ko01000	4-amino-4-deoxychorismate lyase
IPFFCMEA_04340	5.28e-202	folP	2.5.1.15	-	H	ko:K00796	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IPFFCMEA_04341	3.8e-80	folB	1.13.11.81, 4.1.2.25, 5.1.99.8	-	H	ko:K01633	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IPFFCMEA_04342	1.31e-114	folK	2.7.6.3	-	H	ko:K00950	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko00002,ko01000	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IPFFCMEA_04343	1.81e-41	yazB	-	-	K	-	-	-	transcriptional
IPFFCMEA_04344	3.75e-242	dus	-	-	J	ko:K05540	-	ko00000,ko01000,ko03016	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPFFCMEA_04345	0.0	lysS	6.1.1.6	-	J	ko:K04567	ko00970,map00970	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	Belongs to the class-II aminoacyl-tRNA synthetase family
IPFFCMEA_04346	0.0	pyc	6.4.1.1	-	C	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	ko00000,ko00001,ko00002,ko01000	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IPFFCMEA_04347	2.35e-269	ftsW	-	-	D	ko:K03588	ko04112,map04112	ko00000,ko00001,ko02000,ko03036	Belongs to the SEDS family
IPFFCMEA_04348	6.94e-59	ylaN	-	-	S	-	-	-	Belongs to the UPF0358 family
IPFFCMEA_04349	3.49e-219	glsA	3.5.1.2	-	E	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	ko00000,ko00001,ko01000	Belongs to the glutaminase family
IPFFCMEA_04350	9.32e-112	ylaL	-	-	S	-	-	-	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IPFFCMEA_04351	1.41e-315	ylaK	-	-	T	ko:K07175	-	ko00000	ATPase related to phosphate starvation-inducible protein PhoH
IPFFCMEA_04352	2.44e-126	ylaJ	-	-	S	-	-	-	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IPFFCMEA_04353	8.92e-44	ylaI	-	-	S	-	-	-	protein conserved in bacteria
IPFFCMEA_04354	4.4e-63	ylaH	-	-	S	-	-	-	YlaH-like protein
IPFFCMEA_04355	0.0	typA	-	-	T	ko:K06207	-	ko00000	GTP-binding protein TypA
IPFFCMEA_04356	2.21e-30	-	-	-	S	-	-	-	Family of unknown function (DUF5325)
IPFFCMEA_04357	1.74e-57	ylaE	-	-	-	-	-	-	-
IPFFCMEA_04359	1.79e-56	ylaC	-	-	K	ko:K03088	-	ko00000,ko03021	Belongs to the sigma-70 factor family. ECF subfamily
IPFFCMEA_04360	1.44e-56	ylaB	-	-	-	-	-	-	-
IPFFCMEA_04361	0.0	ylaA	-	-	-	-	-	-	-
IPFFCMEA_04362	0.0	mpl	3.4.24.28, 3.4.24.29	-	E	ko:K01400,ko:K01401,ko:K19351	ko01503,ko05150,map01503,map05150	ko00000,ko00001,ko01000,ko01002	Peptidase M4
IPFFCMEA_04363	1.01e-220	-	-	-	Q	-	-	-	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IPFFCMEA_04364	1.17e-97	ykzC	-	-	S	-	-	-	Acetyltransferase (GNAT) family
IPFFCMEA_04365	2.61e-192	suhB	3.1.3.25	-	G	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	ko00000,ko00001,ko00002,ko01000	Inositol monophosphatase
IPFFCMEA_04366	4.48e-35	ykzI	-	-	-	-	-	-	-
IPFFCMEA_04367	2.15e-151	yktB	-	-	S	-	-	-	Belongs to the UPF0637 family
IPFFCMEA_04368	6.37e-55	yktA	-	-	S	-	-	-	Belongs to the UPF0223 family
IPFFCMEA_04369	0.0	speA	4.1.1.17, 4.1.1.19	-	E	ko:K01581,ko:K01585	ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130	ko00000,ko00001,ko00002,ko01000	Arginine
IPFFCMEA_04371	5.08e-26	xkdM	-	-	S	-	-	-	Phage tail tube protein
IPFFCMEA_04372	2.43e-14	-	-	-	-	-	-	-	-
IPFFCMEA_04375	7.44e-05	-	-	-	S	-	-	-	Bacillus cereus group antimicrobial protein
IPFFCMEA_04378	1.24e-194	bltR	-	-	K	-	-	-	helix_turn_helix, mercury resistance
IPFFCMEA_04379	1.08e-268	blt	-	-	EGP	ko:K08153,ko:K19578	-	ko00000,ko00002,ko02000	COG0477 Permeases of the major facilitator superfamily
IPFFCMEA_04380	7.23e-107	bltD	2.3.1.57	-	K	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	ko00000,ko00001,ko00002,ko01000	FR47-like protein
IPFFCMEA_04386	3.09e-63	-	-	-	S	-	-	-	dUTPase
IPFFCMEA_04391	1.86e-98	yfmK	2.3.1.128	-	K	ko:K03790	-	ko00000,ko01000,ko03009	acetyltransferase
IPFFCMEA_04392	1.4e-261	yfmL	-	-	L	-	-	-	COG0513 Superfamily II DNA and RNA helicases
IPFFCMEA_04393	0.0	yheS_1	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPFFCMEA_04394	1.76e-303	papA4	-	-	Q	ko:K12240	ko01053,map01053	ko00000,ko00001,ko01008	synthase
IPFFCMEA_04397	1.79e-74	-	-	-	S	-	-	-	Bacteriophage holin family
IPFFCMEA_04398	4.55e-83	slp	-	-	CO	-	-	-	COG0526, thiol-disulfide isomerase and thioredoxins
IPFFCMEA_04399	0.0	pdhD	1.8.1.4	-	C	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IPFFCMEA_04400	5.96e-301	pdhC	2.3.1.12	-	C	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	br01601,ko00000,ko00001,ko00002,ko01000	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IPFFCMEA_04401	3.52e-227	pdhB	1.2.4.1	-	C	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IPFFCMEA_04402	1.51e-258	pdhA	1.2.4.1	-	C	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	br01601,ko00000,ko00001,ko00002,ko01000	COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IPFFCMEA_04403	6.82e-149	ykyA	-	-	L	-	-	-	Putative cell-wall binding lipoprotein
IPFFCMEA_04404	2.24e-19	-	-	-	S	-	-	-	Protein of unknown function (Tiny_TM_bacill)
IPFFCMEA_04405	3.96e-131	def	3.5.1.88	-	J	ko:K01462	-	ko00000,ko01000	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IPFFCMEA_04406	8.28e-187	ykrA	-	-	S	-	-	-	hydrolases of the HAD superfamily
IPFFCMEA_04407	8.98e-42	ykzG	-	-	S	-	-	-	Belongs to the UPF0356 family
IPFFCMEA_04408	0.0	rnjA	-	-	S	ko:K12574	ko03018,map03018	ko00000,ko00001,ko01000,ko03019	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPFFCMEA_04409	0.0	ade	3.5.4.2	-	F	ko:K01486	ko00230,ko01100,map00230,map01100	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IPFFCMEA_04410	1.68e-148	ktrA	-	-	P	ko:K03499	-	ko00000,ko02000	COG0569 K transport systems, NAD-binding component
IPFFCMEA_04411	8.84e-206	ykqA	-	-	P	-	-	-	Gamma-glutamyl cyclotransferase, AIG2-like
IPFFCMEA_04412	6.77e-276	kinC	2.7.13.3	-	T	ko:K07698	ko02020,map02020	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	COG0642 Signal transduction histidine kinase
IPFFCMEA_04414	0.0	yvnB	-	-	Q	-	-	-	Calcineurin-like phosphoesterase
IPFFCMEA_04415	5.23e-172	yvoA	-	-	K	ko:K03710	-	ko00000,ko03000	transcriptional
IPFFCMEA_04416	1.74e-165	nagB	3.5.99.6	-	G	ko:K02564	ko00520,ko01100,map00520,map01100	ko00000,ko00001,ko01000	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IPFFCMEA_04417	5.07e-281	nagA	3.5.1.25	-	G	ko:K01443	ko00520,ko01130,map00520,map01130	ko00000,ko00001,ko01000	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IPFFCMEA_04418	3.62e-217	hprK	-	-	F	ko:K06023	-	ko00000,ko01000	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IPFFCMEA_04419	3.18e-195	lgt	-	-	M	ko:K13292	-	ko00000,ko01000	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IPFFCMEA_04420	4.16e-208	yvoD	-	-	P	-	-	-	COG0370 Fe2 transport system protein B
IPFFCMEA_04421	3.05e-153	ppaX	3.6.1.1	-	S	ko:K06019	ko00190,map00190	ko00000,ko00001,ko01000	Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IPFFCMEA_04422	5.94e-118	yvoF	2.3.1.79	-	S	ko:K00661	-	ko00000,ko01000	COG0110 Acetyltransferase (isoleucine patch superfamily)
IPFFCMEA_04423	1.13e-11	-	-	-	S	-	-	-	YpzI-like protein
IPFFCMEA_04424	1.11e-133	yphA	-	-	-	-	-	-	-
IPFFCMEA_04425	4.35e-207	yphB	-	-	S	ko:K05739	-	ko00000	YIEGIA protein
IPFFCMEA_04426	2.06e-38	ypzH	-	-	-	-	-	-	-
IPFFCMEA_04427	5.72e-316	der	-	-	S	ko:K03977	-	ko00000,ko03009	GTPase that plays an essential role in the late steps of ribosome biogenesis
IPFFCMEA_04428	2.01e-243	gpsA	1.1.1.94	-	I	ko:K00057	ko00564,ko01110,map00564,map01110	ko00000,ko00001,ko01000	Glycerol-3-phosphate dehydrogenase
IPFFCMEA_04429	1.43e-26	yphE	-	-	S	-	-	-	Protein of unknown function (DUF2768)
IPFFCMEA_04430	8.71e-176	yphF	-	-	-	-	-	-	-
IPFFCMEA_04431	0.0	spoIVA	-	-	S	ko:K06398	-	ko00000	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IPFFCMEA_04432	1.07e-57	hbs	-	-	L	ko:K03530	-	ko00000,ko03032,ko03036,ko03400	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IPFFCMEA_04433	4.02e-109	-	-	-	S	ko:K21488	-	ko00000,ko02048	SMI1-KNR4 cell-wall
IPFFCMEA_04434	0.0	-	-	-	L	ko:K21487	-	ko00000,ko01000,ko02048	A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IPFFCMEA_04436	2.51e-13	-	-	-	-	-	-	-	-
IPFFCMEA_04437	1.25e-56	-	-	-	K	-	-	-	helix_turn_helix, Arsenical Resistance Operon Repressor
IPFFCMEA_04438	2.06e-85	yurT	-	-	E	-	-	-	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IPFFCMEA_04439	1.93e-213	panE1	1.1.1.169	-	H	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	ko00000,ko00001,ko00002,ko01000	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IPFFCMEA_04440	0.0	ykpA	-	-	S	-	-	-	COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IPFFCMEA_04441	5.43e-52	ykoA	-	-	-	-	-	-	-
IPFFCMEA_04442	1.72e-134	sipT	3.4.21.89	-	U	ko:K03100	ko02024,ko03060,map02024,map03060	ko00000,ko00001,ko01000,ko01002	Belongs to the peptidase S26 family
IPFFCMEA_04443	0.0	fruA	2.7.1.202	-	GT	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	ko00000,ko00001,ko00002,ko01000,ko02000	COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IPFFCMEA_04444	9.99e-216	pfkB	2.7.1.56	-	G	ko:K00882	ko00051,map00051	ko00000,ko00001,ko01000	Belongs to the carbohydrate kinase PfkB family
IPFFCMEA_04445	1.75e-174	fruR	-	-	K	ko:K03436	-	ko00000,ko03000	Transcriptional regulator
IPFFCMEA_04446	5.51e-265	yknZ	-	-	V	ko:K02004	-	ko00000,ko00002,ko02000	COG0577 ABC-type antimicrobial peptide transport system, permease component
IPFFCMEA_04447	3.53e-159	yknY	-	-	V	ko:K02003	-	ko00000,ko00002,ko02000	ABC transporter, ATP-binding protein
IPFFCMEA_04448	8.16e-234	yknX	-	-	M	ko:K02005,ko:K13888	-	ko00000,ko00002,ko02000	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPFFCMEA_04449	1.31e-150	yknW	-	-	S	-	-	-	Yip1 domain
IPFFCMEA_04450	0.0	yknV	-	-	V	ko:K02021,ko:K06147,ko:K18890	ko02010,map02010	ko00000,ko00001,ko00002,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPFFCMEA_04451	0.0	yknU	-	-	V	ko:K06147,ko:K11085	ko02010,map02010	ko00000,ko00001,ko01000,ko02000	COG1132 ABC-type multidrug transport system, ATPase and permease components
IPFFCMEA_04452	2.82e-44	moaD	-	-	H	ko:K03636	ko04122,map04122	ko00000,ko00001	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IPFFCMEA_04453	6.61e-110	moaE	2.8.1.12	-	H	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	ko00000,ko00001,ko01000	COG0314 Molybdopterin converting factor, large subunit
IPFFCMEA_04454	8.11e-121	mobB	-	-	H	ko:K03753	-	ko00000	molybdopterin-guanine dinucleotide biosynthesis protein
IPFFCMEA_04455	7.12e-312	moeA	2.10.1.1	-	H	ko:K03750	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	molybdopterin
IPFFCMEA_04456	7.59e-245	moeB	2.7.7.73, 2.7.7.80	-	H	ko:K03148,ko:K21029	ko00730,ko01100,ko04122,map00730,map01100,map04122	ko00000,ko00001,ko01000	COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IPFFCMEA_04457	9.21e-142	mobA	2.7.7.77	-	H	ko:K03752	ko00790,ko01100,map00790,map01100	ko00000,ko00001,ko01000	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IPFFCMEA_04458	9.46e-198	yknT	-	-	-	ko:K06437	-	ko00000	-
IPFFCMEA_04461	3.07e-27	-	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04471	0.0	pyrG	6.3.4.2	-	F	ko:K01937	ko00240,ko01100,map00240,map01100	ko00000,ko00001,ko00002,ko01000	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IPFFCMEA_04472	3.27e-80	rpoE	-	-	K	ko:K03048	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	br01611,ko00000,ko00001,ko00002,ko03021,ko03400	Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IPFFCMEA_04473	5.77e-267	acdA	-	-	I	-	-	-	acyl-CoA dehydrogenase
IPFFCMEA_04474	0.0	ywjF	-	-	C	-	-	-	COG0247 Fe-S oxidoreductase
IPFFCMEA_04475	4.28e-274	clsB	-	-	I	ko:K06131	ko00564,ko01100,map00564,map01100	ko00000,ko00001,ko01000	Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IPFFCMEA_04476	3.3e-234	uvsE	-	-	L	ko:K13281	-	ko00000,ko01000	Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IPFFCMEA_04479	9.58e-67	-	-	-	M	-	-	-	ArpU family transcriptional regulator
IPFFCMEA_04480	1.6e-94	-	-	-	L	-	-	-	Phage integrase family
IPFFCMEA_04481	8.22e-48	-	-	-	S	-	-	-	Protein of unknown function (DUF1433)
IPFFCMEA_04482	1.02e-297	yrkA	-	-	S	-	-	-	COG1253 Hemolysins and related proteins containing CBS domains
IPFFCMEA_04483	2.45e-23	-	-	-	S	-	-	-	YrzO-like protein
IPFFCMEA_04484	3.17e-212	yrdR	-	-	EG	-	-	-	EamA-like transporter family
IPFFCMEA_04485	1.4e-203	-	-	-	K	-	-	-	Transcriptional regulator
IPFFCMEA_04486	1.23e-253	trkA	-	-	P	ko:K07222	-	ko00000	Oxidoreductase
IPFFCMEA_04487	9.05e-207	czcD	-	-	P	ko:K16264	-	ko00000,ko02000	COG1230 Co Zn Cd efflux system component
IPFFCMEA_04488	1.18e-252	-	-	-	L	-	-	-	COG3385 FOG Transposase and inactivated derivatives
IPFFCMEA_04489	1.91e-31	yqgW	-	-	S	-	-	-	Protein of unknown function (DUF2759)
IPFFCMEA_04490	1.3e-156	yqgX	3.1.2.6	-	S	ko:K01069	ko00620,map00620	ko00000,ko00001,ko01000	COG0491 Zn-dependent hydrolases, including glyoxylases
IPFFCMEA_04491	5.6e-173	-	-	-	L	-	-	-	Integrase core domain
IPFFCMEA_04492	7.55e-59	orfX1	-	-	L	-	-	-	Transposase
IPFFCMEA_04493	2.47e-268	VCP	-	-	O	-	-	-	AAA domain (dynein-related subfamily)
IPFFCMEA_04494	2.71e-103	yjoA	-	-	S	-	-	-	DinB family
IPFFCMEA_04501	2.53e-139	ydcA	-	-	S	-	-	-	membrane protein (homolog of Drosophila rhomboid)