ORF_ID e_value Gene_name EC_number CAZy COGs KEGG_ko KEGG_Pathway BRITE Description
PGHHMJKG_00002 2.66e-120 yebE - - S - - - UPF0316 protein
PGHHMJKG_00003 3.13e-38 yebG - - S - - - NETI protein
PGHHMJKG_00004 2.28e-108 purE 5.4.99.18 - F ko:K01588 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PGHHMJKG_00005 2.69e-277 purK 6.3.4.18 - F ko:K01589 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PGHHMJKG_00006 6.85e-315 purB 4.3.2.2 - F ko:K01756 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PGHHMJKG_00007 5.86e-168 purC 6.3.2.6 - F ko:K01923 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the SAICAR synthetase family
PGHHMJKG_00008 3.79e-52 purS 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGHHMJKG_00009 1.15e-167 purQ 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGHHMJKG_00010 0.0 purL 6.3.5.3 - F ko:K01952 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PGHHMJKG_00011 0.0 purF 2.4.2.14 - F ko:K00764 ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PGHHMJKG_00012 9.88e-240 purM 6.3.3.1 - F ko:K01933 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoribosylformylglycinamidine cyclo-ligase
PGHHMJKG_00013 3.62e-137 purN 2.1.2.2 - F ko:K11175 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PGHHMJKG_00014 0.0 purH 2.1.2.3, 3.5.4.10 - F ko:K00602 ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523 ko00000,ko00001,ko00002,ko01000,ko04147 Bifunctional purine biosynthesis protein PurH
PGHHMJKG_00015 5.45e-296 purD 6.3.4.13 - F ko:K01945 ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the GARS family
PGHHMJKG_00016 7.5e-92 - - - K - - - helix_turn_helix ASNC type
PGHHMJKG_00017 1.49e-240 - - - E ko:K16263 - ko00000,ko02000 Amino acid permease
PGHHMJKG_00018 3.45e-37 - - - S - - - Protein of unknown function (DUF2892)
PGHHMJKG_00019 0.0 yerA 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 adenine deaminase
PGHHMJKG_00020 9.58e-244 yerB - - S - - - Protein of unknown function (DUF3048) C-terminal domain
PGHHMJKG_00021 6.27e-67 yerC - - S - - - protein conserved in bacteria
PGHHMJKG_00022 0.0 yerD 1.4.7.1 - E ko:K00284 ko00630,ko00910,ko01120,map00630,map00910,map01120 ko00000,ko00001,ko01000 Belongs to the glutamate synthase family
PGHHMJKG_00024 7.43e-160 pcrB - - I ko:K07094 - ko00000,ko01000 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PGHHMJKG_00025 0.0 pcrA 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA helicase
PGHHMJKG_00026 0.0 ligA 6.5.1.2 - L ko:K01972 ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430 ko00000,ko00001,ko01000,ko03032,ko03400 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PGHHMJKG_00027 1.77e-281 camS - - S - - - COG4851 Protein involved in sex pheromone biosynthesis
PGHHMJKG_00028 4.95e-250 yerI - - S - - - homoserine kinase type II (protein kinase fold)
PGHHMJKG_00029 2.29e-160 sapB - - S ko:K07507 - ko00000,ko02000 MgtC SapB transporter
PGHHMJKG_00030 0.0 putP - - E ko:K03307,ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGHHMJKG_00031 7.37e-61 gatC 6.3.5.6, 6.3.5.7 - J ko:K02435 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGHHMJKG_00032 0.0 gatA 6.3.5.6, 6.3.5.7 - J ko:K02433 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PGHHMJKG_00033 0.0 gatB 6.3.5.6, 6.3.5.7 - J ko:K02434 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko01000,ko03029 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PGHHMJKG_00034 2.08e-190 yerO - - K - - - Transcriptional regulator
PGHHMJKG_00035 0.0 swrC - - V ko:K03296 - ko00000 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PGHHMJKG_00036 1.8e-218 dagK 2.7.1.107 - I ko:K07029 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko01000 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PGHHMJKG_00037 0.0 rlmCD 2.1.1.190 - J ko:K03215 - ko00000,ko01000,ko03009 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGHHMJKG_00038 0.0 - - - L - - - Type III restriction enzyme res subunit
PGHHMJKG_00042 1.59e-124 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_00044 5.1e-36 - - - - - - - -
PGHHMJKG_00045 3.39e-98 - - - S - - - Protein of unknown function, DUF600
PGHHMJKG_00046 0.0 - - - L - - - nucleic acid phosphodiester bond hydrolysis
PGHHMJKG_00048 2.44e-127 - - - L - - - endonuclease activity
PGHHMJKG_00049 1.23e-14 - - - S - - - Pfam:DUF1311
PGHHMJKG_00050 4.97e-271 rapH - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
PGHHMJKG_00052 6.29e-162 yeeN - - K - - - transcriptional regulatory protein
PGHHMJKG_00054 7.28e-132 dhaR3 - - K ko:K16137 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00055 4.59e-101 yesE - - S ko:K06893 - ko00000 SnoaL-like domain
PGHHMJKG_00056 1.13e-193 yesF - - GM - - - NAD(P)H-binding
PGHHMJKG_00057 3.8e-60 cotJA - - S ko:K06332 - ko00000 Spore coat associated protein JA (CotJA)
PGHHMJKG_00058 2.31e-61 cotJB - - S ko:K06333 - ko00000 CotJB protein
PGHHMJKG_00059 6.05e-133 cotJC - - P ko:K06334 - ko00000 Spore Coat
PGHHMJKG_00060 1.19e-130 yesJ - - K - - - Acetyltransferase (GNAT) family
PGHHMJKG_00061 2.56e-132 yesL - - S - - - Protein of unknown function, DUF624
PGHHMJKG_00062 0.0 yesM 2.7.13.3 - T ko:K07718 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_00063 7.1e-163 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
PGHHMJKG_00064 1.32e-69 - - - K ko:K07720 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 helix_turn_helix, arabinose operon control protein
PGHHMJKG_00065 6.85e-313 yesO - - G ko:K02027 - ko00000,ko00002,ko02000 Bacterial extracellular solute-binding protein
PGHHMJKG_00066 6.98e-77 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PGHHMJKG_00067 3.57e-120 yesP - - G ko:K02025 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PGHHMJKG_00068 8.84e-211 - - - P ko:K02026 - ko00000,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PGHHMJKG_00069 8e-254 - 3.2.1.172 GH105 S ko:K15532 - ko00000,ko01000 Glycosyl Hydrolase Family 88
PGHHMJKG_00070 0.0 yesS - - K - - - Transcriptional regulator
PGHHMJKG_00071 5.05e-171 - - - E - - - GDSL-like Lipase/Acylhydrolase
PGHHMJKG_00072 1.07e-164 yesU - - S - - - Domain of unknown function (DUF1961)
PGHHMJKG_00073 4.69e-144 - - - S - - - Protein of unknown function, DUF624
PGHHMJKG_00074 0.0 - 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
PGHHMJKG_00075 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E ko:K18197,ko:K18198 - ko00000,ko01000 cell wall organization
PGHHMJKG_00076 7.51e-159 - - - E - - - GDSL-like Lipase/Acylhydrolase
PGHHMJKG_00077 0.0 - 3.2.1.23 - G ko:K01190 ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100 ko00000,ko00001,ko01000 beta-galactosidase activity
PGHHMJKG_00078 2.25e-127 yetA - - - - - - -
PGHHMJKG_00079 0.0 yetA - - - - - - -
PGHHMJKG_00080 0.0 lplA - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PGHHMJKG_00081 1.18e-226 lplB - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
PGHHMJKG_00082 7.85e-209 - - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PGHHMJKG_00083 0.0 - 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PGHHMJKG_00084 3.66e-157 yetF - - S - - - membrane
PGHHMJKG_00085 1.57e-71 yetG 1.14.99.48 - S ko:K07145 ko00860,ko01110,map00860,map01110 ko00000,ko00001,ko01000 Antibiotic biosynthesis monooxygenase
PGHHMJKG_00086 2.47e-85 yetH - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHHMJKG_00092 3.09e-63 - - - S - - - dUTPase
PGHHMJKG_00099 1.75e-227 thiL 2.7.4.16 - H ko:K00946 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PGHHMJKG_00100 3.68e-112 ydiB - - S ko:K06925 - ko00000,ko03016 ATPase or kinase
PGHHMJKG_00101 2.8e-160 yeaZ 2.3.1.234 - O ko:K01409,ko:K14742 - ko00000,ko01000,ko03016 COG1214 Inactive homolog of metal-dependent proteases
PGHHMJKG_00102 2e-108 rimI 2.3.1.128 - K ko:K03789 - ko00000,ko01000,ko03009 This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PGHHMJKG_00103 1.34e-240 tsaD 2.3.1.234 - O ko:K01409 - ko00000,ko01000,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PGHHMJKG_00104 0.0 ydiF - - S ko:K06158 - ko00000,ko03012 ABC transporter
PGHHMJKG_00105 1.46e-117 moaC 4.6.1.17 - H ko:K03637 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PGHHMJKG_00106 2.14e-148 rex - - K ko:K01926 - ko00000,ko03000 Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PGHHMJKG_00107 5.48e-31 tatA - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PGHHMJKG_00108 3.55e-161 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGHHMJKG_00109 3.2e-37 ydiK - - S - - - Domain of unknown function (DUF4305)
PGHHMJKG_00110 3e-167 ydiL - - S ko:K07052 - ko00000 CAAX protease self-immunity
PGHHMJKG_00111 2.14e-58 groS - - O ko:K04078 - ko00000,ko03029,ko03110 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PGHHMJKG_00112 0.0 groL - - O ko:K04077 ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PGHHMJKG_00113 1.91e-182 - - - L - - - Belongs to the 'phage' integrase family
PGHHMJKG_00114 2.71e-61 xkdA - - E - - - IrrE N-terminal-like domain
PGHHMJKG_00115 6.71e-28 - - - K - - - transcriptional
PGHHMJKG_00116 1.5e-26 - - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_00117 1.68e-48 - - - - - - - -
PGHHMJKG_00118 1.22e-48 - - - S - - - DNA binding
PGHHMJKG_00119 3.14e-110 - - - - - - - -
PGHHMJKG_00124 8.41e-125 - - - - - - - -
PGHHMJKG_00125 1.8e-87 pi112 - - L - - - PDDEXK-like domain of unknown function (DUF3799)
PGHHMJKG_00127 4.69e-96 yqaL - - L - - - DnaD domain protein
PGHHMJKG_00128 6.06e-102 yqaM - - L - - - IstB-like ATP binding protein
PGHHMJKG_00130 2.02e-81 rusA - - L - - - Endodeoxyribonuclease RusA
PGHHMJKG_00131 1.78e-34 yqaO - - S - - - Phage-like element PBSX protein XtrA
PGHHMJKG_00134 1.19e-37 - - - - - - - -
PGHHMJKG_00135 6e-147 - - - - - - - -
PGHHMJKG_00137 1.84e-105 - - - L - - - Transposase
PGHHMJKG_00138 7.11e-39 - - - - - - - -
PGHHMJKG_00140 1.19e-66 - - - V ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
PGHHMJKG_00141 5.19e-102 - - - L - - - phage terminase small subunit
PGHHMJKG_00142 0.0 - - - S - - - Terminase
PGHHMJKG_00144 2.64e-303 - - - S - - - Phage portal protein
PGHHMJKG_00145 6.14e-151 - - - OU - - - Belongs to the peptidase S14 family
PGHHMJKG_00146 1.06e-266 - - - S - - - capsid protein
PGHHMJKG_00147 1.89e-34 - - - - - - - -
PGHHMJKG_00148 1.4e-50 - - - S - - - Phage gp6-like head-tail connector protein
PGHHMJKG_00149 5.23e-52 - - - S - - - Phage head-tail joining protein
PGHHMJKG_00150 8.4e-67 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PGHHMJKG_00152 1.67e-101 - - - N - - - Phage major tail protein phi13
PGHHMJKG_00153 1.77e-05 - - - - - - - -
PGHHMJKG_00155 0.0 - - - D - - - phage tail tape measure protein
PGHHMJKG_00156 1.19e-135 - - - S - - - Phage tail protein
PGHHMJKG_00157 1.92e-275 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
PGHHMJKG_00163 1.76e-59 - - - S - - - dUTPase
PGHHMJKG_00165 1.12e-07 - - - S - - - YopX protein
PGHHMJKG_00167 9.15e-145 yyaC - - S - - - Sporulation protein YyaC
PGHHMJKG_00168 5.34e-227 yyaD - - S - - - Membrane
PGHHMJKG_00169 7.41e-45 yyzM - - S - - - protein conserved in bacteria
PGHHMJKG_00170 0.0 yyaE - - C - - - Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PGHHMJKG_00171 5.65e-256 ychF - - J ko:K06942 - ko00000,ko03009 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PGHHMJKG_00172 1.01e-61 rpsF - - J ko:K02990 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Binds together with S18 to 16S ribosomal RNA
PGHHMJKG_00173 1.81e-103 ssb - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PGHHMJKG_00174 4.25e-49 rpsR - - J ko:K02963 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PGHHMJKG_00175 2.07e-187 exoA 3.1.11.2 - L ko:K01142 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 exodeoxyribonuclease III
PGHHMJKG_00176 2.65e-60 ccpB - - K - - - Transcriptional regulator
PGHHMJKG_00177 2.14e-154 ccpB - - K - - - Transcriptional regulator
PGHHMJKG_00178 4.69e-86 yyaH 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHHMJKG_00179 3.01e-126 vatD 2.3.1.28, 2.3.1.79 - S ko:K00638,ko:K00661,ko:K18234 - br01600,ko00000,ko01000,ko01504 Bacterial transferase hexapeptide (six repeats)
PGHHMJKG_00180 0.0 - - - EGP ko:K08369 - ko00000,ko02000 Major facilitator superfamily
PGHHMJKG_00181 2.1e-215 yyaK - - S ko:K07052 - ko00000 CAAX protease self-immunity
PGHHMJKG_00182 0.0 yyaL - - O ko:K06888 - ko00000 COG1331 Highly conserved protein containing a thioredoxin domain
PGHHMJKG_00183 3.47e-108 - - - L - - - Bacterial transcription activator, effector binding domain
PGHHMJKG_00184 1.67e-134 yyaP - - H - - - RibD C-terminal domain
PGHHMJKG_00185 2.25e-15 - - - S - - - YjbR
PGHHMJKG_00186 2.28e-48 - - - S - - - YjbR
PGHHMJKG_00187 3.81e-87 - - - K ko:K19273 - ko00000,ko01000,ko01504 Acetyltransferase (GNAT) domain
PGHHMJKG_00188 1.55e-125 yyaS - - S ko:K07149 - ko00000 Membrane
PGHHMJKG_00189 4.18e-90 yjcF - - S - - - Acetyltransferase (GNAT) domain
PGHHMJKG_00190 4.54e-100 yybA - - K - - - transcriptional
PGHHMJKG_00191 4.41e-105 - - - S - - - Metallo-beta-lactamase superfamily
PGHHMJKG_00192 3.87e-132 yybF - - EGP ko:K08224 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_00193 6.02e-157 yybG - - S - - - Pentapeptide repeat-containing protein
PGHHMJKG_00194 5.02e-87 - - - S - - - SnoaL-like domain
PGHHMJKG_00195 2.05e-183 - - - - - - - -
PGHHMJKG_00196 7.24e-141 - - - K - - - TipAS antibiotic-recognition domain
PGHHMJKG_00197 7.94e-200 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_00198 5.21e-70 yybO - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_00200 3.19e-90 - - - - - - - -
PGHHMJKG_00201 2.83e-209 ppaC 3.6.1.1 - C ko:K15986 ko00190,map00190 ko00000,ko00001,ko01000 Inorganic pyrophosphatase
PGHHMJKG_00202 1.3e-87 yybR - - K - - - Transcriptional regulator
PGHHMJKG_00203 1.71e-67 cotF - - M ko:K06329 - ko00000 Spore coat protein
PGHHMJKG_00204 6.16e-20 cotF - - M ko:K06329 - ko00000 Spore coat protein
PGHHMJKG_00206 4.15e-120 yybS - - S - - - membrane
PGHHMJKG_00207 1.14e-34 yybS - - S - - - membrane
PGHHMJKG_00208 0.0 yybT - - T - - - signaling protein consisting of a modified GGDEF domain and a DHH domain
PGHHMJKG_00209 2.74e-96 rplI - - J ko:K02939 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PGHHMJKG_00210 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PGHHMJKG_00211 1.15e-280 yycB - - P ko:K03449 - ko00000,ko02000 COG2807 Cyanate permease
PGHHMJKG_00212 1.89e-22 yycC - - K - - - YycC-like protein
PGHHMJKG_00214 2.87e-39 yycD - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PGHHMJKG_00215 0.0 dnaB 3.6.4.12 - L ko:K02314 ko03030,ko04112,map03030,map04112 ko00000,ko00001,ko01000,ko03032 Participates in initiation and elongation during chromosome replication
PGHHMJKG_00216 3.17e-97 yycE - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHHMJKG_00217 3.02e-313 purA 6.3.4.4 - F ko:K01939 ko00230,ko00250,ko01100,map00230,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PGHHMJKG_00222 2.07e-172 yycF - - T ko:K07668 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_00223 0.0 vicK 2.7.13.3 - T ko:K07652 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_00224 0.0 yycH - - S - - - protein conserved in bacteria
PGHHMJKG_00225 3.44e-200 yycI - - S - - - protein conserved in bacteria
PGHHMJKG_00226 1.15e-190 vicX 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PGHHMJKG_00227 2.32e-279 yyxA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGHHMJKG_00228 0.0 rocR - - KT ko:K06714 - ko00000,ko03000 COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PGHHMJKG_00229 2.31e-54 sdpR - - K - - - transcriptional
PGHHMJKG_00230 3.95e-87 yvaZ - - S - - - Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PGHHMJKG_00231 6.81e-19 - - - S - - - Sporulation delaying protein SdpA
PGHHMJKG_00232 4.85e-119 - - - - - - - -
PGHHMJKG_00233 5.82e-20 - - - - - - - -
PGHHMJKG_00234 1.01e-294 rocD 2.6.1.13 - E ko:K00819 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000,ko01007 Catalyzes the interconversion of ornithine to glutamate semialdehyde
PGHHMJKG_00235 0.0 rocE - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PGHHMJKG_00236 3.22e-213 rocF 3.5.3.1 - E ko:K01476 ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PGHHMJKG_00238 2.06e-204 - - - S - - - aspartate phosphatase
PGHHMJKG_00239 1.17e-18 - - - S - - - aspartate phosphatase
PGHHMJKG_00240 4.15e-108 yycN - - K - - - Acetyltransferase
PGHHMJKG_00241 3.06e-156 yycO - - S - - - Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PGHHMJKG_00242 1.37e-22 yycP - - - - - - -
PGHHMJKG_00243 2.65e-207 yycP - - - - - - -
PGHHMJKG_00244 4.53e-41 yycQ - - S - - - Protein of unknown function (DUF2651)
PGHHMJKG_00246 2.12e-296 yycR 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PGHHMJKG_00247 1.64e-89 - - - - - - - -
PGHHMJKG_00249 5e-106 rlmH 2.1.1.177 - J ko:K00783 - ko00000,ko01000,ko03009 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PGHHMJKG_00251 3.91e-135 - - - L - - - helicase superfamily c-terminal domain
PGHHMJKG_00252 1.59e-65 - - - L - - - Transposase
PGHHMJKG_00253 3.17e-176 - - - L ko:K07497 - ko00000 COG2801 Transposase and inactivated derivatives
PGHHMJKG_00254 3.99e-53 - - - - - - - -
PGHHMJKG_00256 1.07e-57 - - - S - - - transposition, DNA-mediated
PGHHMJKG_00257 6.23e-148 - - - S - - - HTH-like domain
PGHHMJKG_00258 0.0 - - - L - - - AAA ATPase domain
PGHHMJKG_00259 0.0 - - - L - - - Superfamily I DNA and RNA helicases
PGHHMJKG_00260 0.0 - - - V - - - Abi-like protein
PGHHMJKG_00261 6.83e-45 - - - - - - - -
PGHHMJKG_00262 4.95e-180 proG 1.5.1.2 - E ko:K00286,ko:K02239 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko02044 Pyrroline-5-carboxylate reductase
PGHHMJKG_00263 2.73e-287 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGHHMJKG_00265 1.28e-228 ykcC - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PGHHMJKG_00266 0.0 ykcB - - M - - - COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PGHHMJKG_00267 8.07e-233 ykcA - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PGHHMJKG_00268 1.81e-309 steT - - E ko:K03294 - ko00000 amino acid
PGHHMJKG_00269 1.85e-144 ykaA - - P ko:K07220 - ko00000 COG1392 Phosphate transport regulator (distant homolog of PhoU)
PGHHMJKG_00270 1.54e-225 pit - - P ko:K03306 - ko00000 phosphate transporter
PGHHMJKG_00271 1.19e-175 spoIISA - - S ko:K06388 - ko00000 Toxin SpoIISA, type II toxin-antitoxin system
PGHHMJKG_00272 1.78e-31 spoIISB - - S ko:K06389 - ko00000 Stage II sporulation protein SB
PGHHMJKG_00273 3.2e-209 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PGHHMJKG_00274 1.15e-52 xhlB - - S - - - SPP1 phage holin
PGHHMJKG_00275 2.21e-51 xhlA - - S - - - Haemolysin XhlA
PGHHMJKG_00276 9.79e-195 xepA - - - - - - -
PGHHMJKG_00277 6.35e-31 xkdX - - - - - - -
PGHHMJKG_00278 2.7e-68 xkdW - - S - - - XkdW protein
PGHHMJKG_00279 0.0 - - - - - - - -
PGHHMJKG_00280 4.43e-56 - - - - - - - -
PGHHMJKG_00281 3.92e-135 - - - S - - - Uncharacterised protein conserved in bacteria (DUF2313)
PGHHMJKG_00282 7.59e-245 - - - S - - - Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PGHHMJKG_00283 3.82e-90 xkdS - - S - - - Protein of unknown function (DUF2634)
PGHHMJKG_00284 4.32e-53 xkdR - - S - - - Protein of unknown function (DUF2577)
PGHHMJKG_00285 2.31e-232 xkdQ - - G - - - NLP P60 protein
PGHHMJKG_00286 1.73e-151 xkdP - - S - - - Lysin motif
PGHHMJKG_00287 0.0 xkdO - - L - - - Transglycosylase SLT domain
PGHHMJKG_00288 9.21e-99 - - - S - - - Phage XkdN-like tail assembly chaperone protein, TAC
PGHHMJKG_00289 2.45e-98 xkdM - - S - - - Phage tail tube protein
PGHHMJKG_00290 0.0 xkdK - - S - - - Phage tail sheath C-terminal domain
PGHHMJKG_00291 2.87e-101 xkdJ - - - - - - -
PGHHMJKG_00292 5.84e-115 xkdI - - S - - - Bacteriophage HK97-gp10, putative tail-component
PGHHMJKG_00293 1.05e-85 yqbH - - S - - - Domain of unknown function (DUF3599)
PGHHMJKG_00294 3.85e-81 yqbG - - S - - - Protein of unknown function (DUF3199)
PGHHMJKG_00295 3.91e-217 xkdG - - S - - - Phage capsid family
PGHHMJKG_00296 4.02e-176 xkdF3 - - L - - - Putative phage serine protease XkdF
PGHHMJKG_00297 0.0 yqbA - - S - - - portal protein
PGHHMJKG_00298 0.0 xtmB - - S ko:K06909 - ko00000 phage terminase, large subunit
PGHHMJKG_00299 1.18e-179 xtmA - - L ko:K07474 - ko00000 phage terminase small subunit
PGHHMJKG_00300 8.12e-110 xpf - - K ko:K03088 - ko00000,ko03021 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PGHHMJKG_00305 8.72e-152 xkdC - - L - - - Bacterial dnaA protein
PGHHMJKG_00306 2.52e-201 xkdB - - K - - - sequence-specific DNA binding
PGHHMJKG_00308 2.01e-74 xre - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_00309 1.53e-144 xkdA - - E - - - IrrE N-terminal-like domain
PGHHMJKG_00310 4.54e-204 yjqC - - P ko:K07217 - ko00000 Catalase
PGHHMJKG_00311 1.11e-138 yjqB - - S - - - Pfam:DUF867
PGHHMJKG_00312 1.35e-80 yjqA - - S - - - Bacterial PH domain
PGHHMJKG_00313 3.09e-217 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PGHHMJKG_00314 1.09e-34 - - - S - - - YCII-related domain
PGHHMJKG_00316 8.59e-272 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_00317 6.25e-270 yutK - - F ko:K03317 - ko00000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGHHMJKG_00318 3.9e-208 dapF 5.1.1.7 - E ko:K01778 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PGHHMJKG_00319 6.81e-83 erpA - - S ko:K13628 - ko00000,ko03016 Belongs to the HesB IscA family
PGHHMJKG_00320 1.36e-123 paiB - - K ko:K07734 - ko00000,ko03000 Putative FMN-binding domain
PGHHMJKG_00321 5.26e-234 guaC 1.7.1.7 - F ko:K00364 ko00230,map00230 ko00000,ko00001,ko01000 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PGHHMJKG_00323 1.92e-239 yumC 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 reductase
PGHHMJKG_00324 1.39e-299 yumB 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PGHHMJKG_00325 1.97e-46 yuiB - - S - - - Putative membrane protein
PGHHMJKG_00326 2.69e-148 yuiC - - S - - - protein conserved in bacteria
PGHHMJKG_00327 8.63e-102 yuiD - - S ko:K09775 - ko00000 protein conserved in bacteria
PGHHMJKG_00328 0.0 pepA 3.4.11.1 - E ko:K01255 ko00480,ko01100,map00480,map01100 ko00000,ko00001,ko01000,ko01002 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PGHHMJKG_00329 3.65e-279 yuiF - - S ko:K07084 - ko00000,ko02000 antiporter
PGHHMJKG_00330 8.33e-125 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Biotin biosynthesis protein
PGHHMJKG_00331 2.36e-157 yuiH - - S - - - Oxidoreductase molybdopterin binding domain
PGHHMJKG_00332 1.27e-212 eSD - - S ko:K07017 - ko00000 Putative esterase
PGHHMJKG_00333 5.83e-178 dhbA 1.3.1.28 - IQ ko:K00216 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_00334 5.78e-288 dhbC 5.4.4.2 - HQ ko:K02361 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PGHHMJKG_00335 0.0 entE 2.7.7.58, 6.3.2.14 - Q ko:K02363,ko:K04783 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 2,3-dihydroxybenzoate-AMP ligase
PGHHMJKG_00336 2.59e-227 dhbB 3.3.2.1, 6.3.2.14 - Q ko:K01252 ko01053,ko01110,ko01130,map01053,map01110,map01130 ko00000,ko00001,ko01000,ko01008 Isochorismatase family
PGHHMJKG_00337 0.0 dhbF - - Q ko:K04780 ko01053,map01053 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHHMJKG_00338 2.02e-47 mbtH - - S ko:K05375 ko00261,ko01130,map00261,map01130 ko00000,ko00001,ko00002 MbtH-like protein
PGHHMJKG_00339 1.2e-168 yukJ - - S - - - Uncharacterized conserved protein (DUF2278)
PGHHMJKG_00340 4.02e-262 ald 1.4.1.1 - E ko:K00259 ko00250,ko00430,ko01100,map00250,map00430,map01100 ko00000,ko00001,ko01000 Belongs to the AlaDH PNT family
PGHHMJKG_00341 2.96e-292 yukF - - QT - - - Transcriptional regulator
PGHHMJKG_00342 3.93e-60 yukE - - S - - - Belongs to the WXG100 family
PGHHMJKG_00343 1.93e-54 yukD - - S - - - WXG100 protein secretion system (Wss), protein YukD
PGHHMJKG_00344 1.93e-267 essB - - S - - - WXG100 protein secretion system (Wss), protein YukC
PGHHMJKG_00345 0.0 essC - - D ko:K03466 - ko00000,ko03036 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PGHHMJKG_00346 0.0 yueB - - S - - - type VII secretion protein EsaA
PGHHMJKG_00347 1.78e-96 yueC - - S - - - Family of unknown function (DUF5383)
PGHHMJKG_00348 6.83e-168 yueD 1.1.1.320 - IQ ko:K16216 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_00349 3.85e-125 yueE - - S ko:K06950 - ko00000 phosphohydrolase
PGHHMJKG_00350 1.19e-32 - - - S - - - Protein of unknown function (DUF2642)
PGHHMJKG_00351 6.59e-92 - - - S - - - Protein of unknown function (DUF2283)
PGHHMJKG_00352 1.35e-244 yueF - - S - - - transporter activity
PGHHMJKG_00353 6.9e-41 yueG - - S ko:K06299 - ko00000 Spore germination protein gerPA/gerPF
PGHHMJKG_00354 1.63e-52 yueH - - S - - - YueH-like protein
PGHHMJKG_00355 8.92e-87 - - - S - - - Protein of unknown function (DUF1694)
PGHHMJKG_00356 3.82e-133 pncA - - Q ko:K16788 - ko00000,ko02000 COG1335 Amidases related to nicotinamidase
PGHHMJKG_00357 0.0 pncB 6.3.4.21 - H ko:K00763 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PGHHMJKG_00358 6.88e-297 yuxH - - T - - - signal transduction protein containing EAL and modified HD-GYP domains
PGHHMJKG_00359 8.73e-09 yuzC - - - - - - -
PGHHMJKG_00361 6.29e-10 - - - S - - - DegQ (SacQ) family
PGHHMJKG_00362 3.33e-168 comQ - - H ko:K02251 ko02024,map02024 ko00000,ko00001,ko02044 Belongs to the FPP GGPP synthase family
PGHHMJKG_00364 0.0 comP 2.7.13.3 - T ko:K07680 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_00365 2.06e-150 comA - - K ko:K07691 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_00366 9.49e-84 yuxO - - Q - - - protein, possibly involved in aromatic compounds catabolism
PGHHMJKG_00367 8.49e-79 mrpG - - P ko:K05571 - ko00000,ko02000 COG1320 Multisubunit Na H antiporter, MnhG subunit
PGHHMJKG_00368 2.23e-51 mrpF - - P ko:K05570 - ko00000,ko02000 Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PGHHMJKG_00369 2.12e-102 mrpE - - P ko:K05569 - ko00000,ko02000 Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PGHHMJKG_00370 0.0 mrpD - - CP ko:K05568 - ko00000,ko02000 Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PGHHMJKG_00371 3.48e-66 mrpC - - P ko:K05567 - ko00000,ko02000 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PGHHMJKG_00372 7.66e-91 mrpB - - P ko:K05566 - ko00000,ko02000 Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PGHHMJKG_00373 0.0 mrpA - - CP ko:K05565 - ko00000,ko02000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PGHHMJKG_00374 1.42e-21 - - - - - - - -
PGHHMJKG_00375 9.73e-310 malP - - C ko:K11616 ko02020,map02020 ko00000,ko00001 COG3493 Na citrate symporter
PGHHMJKG_00376 1.15e-213 yufQ - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGHHMJKG_00377 1.29e-236 yufP - - S ko:K02057 - ko00000,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGHHMJKG_00378 0.0 yufO 3.6.3.17 - S ko:K02056 - ko00000,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_00379 9e-254 tcsA - - S ko:K02058,ko:K07335 - ko00000,ko00002,ko02000 ABC-type transport system, periplasmic component surface lipoprotein
PGHHMJKG_00380 1.88e-161 dcuR - - T ko:K02475,ko:K11615 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PGHHMJKG_00381 0.0 malK 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PGHHMJKG_00382 4.19e-113 yufK - - S - - - Family of unknown function (DUF5366)
PGHHMJKG_00383 1.92e-97 yuxK - - S - - - protein conserved in bacteria
PGHHMJKG_00384 0.0 pbpD 2.4.1.129, 3.4.16.4 GT51 M ko:K12555,ko:K18770 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 Penicillin-binding Protein
PGHHMJKG_00385 4.61e-244 yuxJ - - EGP - - - Major facilitator superfamily
PGHHMJKG_00387 1.71e-149 kapD - - L ko:K06348 - ko00000 the KinA pathway to sporulation
PGHHMJKG_00388 8.36e-90 kapB - - G ko:K06347 ko02020,map02020 ko00000,ko00001 Kinase associated protein B
PGHHMJKG_00389 4.32e-296 kinB2 2.7.13.3 - T ko:K07697 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_00390 3.32e-286 patB 4.4.1.8 - E ko:K14155 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko01000,ko01007 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PGHHMJKG_00391 8.84e-52 yugE - - S - - - Domain of unknown function (DUF1871)
PGHHMJKG_00392 9.89e-201 yugF - - I - - - Hydrolase
PGHHMJKG_00393 6.74e-112 alaR - - K - - - Transcriptional regulator
PGHHMJKG_00394 5.43e-255 yugH - - E ko:K10907 - ko00000,ko01000,ko01007 Aminotransferase
PGHHMJKG_00395 5e-83 yugI - - J ko:K07570,ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PGHHMJKG_00396 2.21e-46 yuzA - - S ko:K09779 - ko00000 Domain of unknown function (DUF378)
PGHHMJKG_00397 2.85e-287 yugJ - - C ko:K19955 - ko00000,ko01000 oxidoreductases, Fe-dependent alcohol dehydrogenase family
PGHHMJKG_00398 1.2e-285 yugK - - C ko:K19955 - ko00000,ko01000 Dehydrogenase
PGHHMJKG_00399 0.0 pgi 5.3.1.9 - G ko:K01810 ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the GPI family
PGHHMJKG_00401 2.75e-91 yugN - - S - - - YugN-like family
PGHHMJKG_00402 1.69e-231 yugO - - P ko:K10716 - ko00000,ko02000 COG1226 Kef-type K transport systems
PGHHMJKG_00403 5.01e-69 mstX - - S - - - Membrane-integrating protein Mistic
PGHHMJKG_00404 2.16e-48 - - - - - - - -
PGHHMJKG_00405 4.8e-150 yugP - - S ko:K06973 - ko00000 Zn-dependent protease
PGHHMJKG_00406 7.23e-300 yugS - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PGHHMJKG_00407 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PGHHMJKG_00408 5e-48 - - - - - - - -
PGHHMJKG_00409 6.15e-181 tgl 2.3.2.13 - H ko:K00686 - ko00000,ko01000 Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links
PGHHMJKG_00410 0.0 mcpB - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_00411 2.02e-284 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_00412 0.0 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_00413 2.35e-115 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_00414 2.61e-185 mcpA - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_00415 0.0 yuxG - - IQ - - - Class II Aldolase and Adducin N-terminal domain
PGHHMJKG_00416 1.42e-172 yulB - - K ko:K02530,ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PGHHMJKG_00417 0.0 rhaB 2.7.1.5 - G ko:K00848 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PGHHMJKG_00418 8.22e-72 rhaM 5.1.3.32 - G ko:K03534 - ko00000,ko01000 Involved in the anomeric conversion of L-rhamnose
PGHHMJKG_00419 0.0 rhaA 2.7.1.5, 5.3.1.14 - G ko:K00848,ko:K01813 ko00040,ko00051,ko01120,map00040,map00051,map01120 ko00000,ko00001,ko01000 Belongs to the rhamnose isomerase family
PGHHMJKG_00420 9.11e-236 yulF - - S ko:K22230 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PGHHMJKG_00421 1.73e-252 yubA - - S - - - transporter activity
PGHHMJKG_00422 1.73e-182 uppP 3.6.1.27 - V ko:K06153 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PGHHMJKG_00424 5.39e-111 cdoA 1.13.11.20 - S ko:K00456 ko00270,ko00430,ko01100,map00270,map00430,map01100 ko00000,ko00001,ko01000 Cysteine dioxygenase type I
PGHHMJKG_00425 0.0 yubD - - P - - - Major Facilitator Superfamily
PGHHMJKG_00426 1.87e-196 - - - NU - - - Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGHHMJKG_00427 3.31e-52 yubF - - S - - - yiaA/B two helix domain
PGHHMJKG_00428 1.07e-300 - - - P ko:K03498 - ko00000,ko02000 Potassium
PGHHMJKG_00429 1.06e-156 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PGHHMJKG_00430 5.83e-118 yuaB - - - - - - -
PGHHMJKG_00431 2.9e-122 yuaC - - K ko:K22109 - ko00000,ko03000 Belongs to the GbsR family
PGHHMJKG_00432 0.0 gbsA 1.2.1.8 - C ko:K00130 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PGHHMJKG_00433 4.26e-292 gbsB 1.1.1.1 - C ko:K11440 ko00260,ko01100,map00260,map01100 ko00000,ko00001,ko00002,ko01000 alcohol dehydrogenase
PGHHMJKG_00434 1.12e-134 yuaD - - - - - - -
PGHHMJKG_00437 1.45e-38 - - - - - - - -
PGHHMJKG_00440 1.73e-70 - - - K - - - Helix-turn-helix
PGHHMJKG_00441 2.11e-49 - - - S - - - TM2 domain
PGHHMJKG_00442 2.62e-157 xlnB 3.2.1.8 - G ko:K01181 - ko00000,ko01000 Glycosyl hydrolases family 11
PGHHMJKG_00443 0.0 pps 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 phosphoenolpyruvate synthase
PGHHMJKG_00446 8.51e-214 penP 3.5.2.6 - V ko:K17836,ko:K18766 ko00311,ko01130,ko01501,map00311,map01130,map01501 ko00000,ko00001,ko00002,ko01000,ko01504 beta-lactamase
PGHHMJKG_00447 4.88e-147 lin0465 - - S - - - DJ-1/PfpI family
PGHHMJKG_00448 1.89e-100 yoaW - - - - - - -
PGHHMJKG_00449 3.7e-201 yoaV - - EG - - - EamA-like transporter family
PGHHMJKG_00450 1.35e-202 yoaU - - K - - - LysR substrate binding domain
PGHHMJKG_00451 5.46e-189 yoaT - - S - - - Protein of unknown function (DUF817)
PGHHMJKG_00452 7e-40 yozG - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00453 3.22e-98 yoaS - - S - - - Protein of unknown function (DUF2975)
PGHHMJKG_00454 5.78e-215 yoaR - - V - - - vancomycin resistance protein
PGHHMJKG_00455 2.01e-108 - - - - - - - -
PGHHMJKG_00458 3.1e-291 oxdD 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PGHHMJKG_00460 1.27e-105 yoqW - - S - - - Belongs to the SOS response-associated peptidase family
PGHHMJKG_00461 2.87e-119 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
PGHHMJKG_00462 1.79e-66 - 4.2.2.10 - G ko:K01732 - ko00000,ko01000 Amb_all
PGHHMJKG_00463 1.79e-145 yoaK - - S - - - Membrane
PGHHMJKG_00464 3.56e-169 yoaJ - - G ko:K20628 - ko00000 Endoglucanase C-terminal domain subunit and related proteins
PGHHMJKG_00465 0.0 yoaI 1.14.14.9 - Q ko:K00483 ko00350,ko01120,ko01220,map00350,map01120,map01220 ko00000,ko00001,ko01000 COG2368 Aromatic ring hydroxylase
PGHHMJKG_00466 1.88e-19 yoaH - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 methyl-accepting chemotaxis protein
PGHHMJKG_00467 5.32e-60 - - - L - - - Transposase and inactivated derivatives, TnpA family
PGHHMJKG_00468 2.2e-100 - - - - - - - -
PGHHMJKG_00469 5.09e-42 - 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PGHHMJKG_00470 5.92e-194 - - - EG - - - Spore germination protein
PGHHMJKG_00471 2.28e-13 - - - S - - - TIGRFAM germination protein, Ger(x)C family
PGHHMJKG_00472 2.56e-34 - - - S - - - Protein of unknown function (DUF2642)
PGHHMJKG_00473 7.51e-205 - - - P - - - Catalase
PGHHMJKG_00475 3.72e-36 - - - S - - - Protein of unknown function (DUF1657)
PGHHMJKG_00476 5.84e-105 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PGHHMJKG_00477 1e-249 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PGHHMJKG_00478 4.34e-75 spoVAE - - S ko:K06407 - ko00000 stage V sporulation protein
PGHHMJKG_00479 1.15e-39 - - - S - - - Protein of unknown function (DUF1657)
PGHHMJKG_00480 9.73e-194 - - - S - - - membrane
PGHHMJKG_00481 1.38e-16 - - - S - - - Protein of unknown function (DUF421)
PGHHMJKG_00482 1.92e-92 - - - S - - - Protein of unknown function (DUF421)
PGHHMJKG_00483 0.0 - - - I - - - PLD-like domain
PGHHMJKG_00484 7.71e-128 - - - S - - - Protein of unknown function (DUF421)
PGHHMJKG_00485 2.23e-112 lsrK 2.7.1.189 - G ko:K11216 ko02024,map02024 ko00000,ko00001,ko01000 FGGY family of carbohydrate kinases, C-terminal domain
PGHHMJKG_00486 2.24e-300 yoaB - - EGP - - - the major facilitator superfamily
PGHHMJKG_00487 8.15e-105 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PGHHMJKG_00488 7.41e-179 - - - V ko:K01990 - ko00000,ko00002,ko02000 AAA domain, putative AbiEii toxin, Type IV TA system
PGHHMJKG_00489 2.92e-120 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PGHHMJKG_00490 6.24e-168 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PGHHMJKG_00491 2.31e-122 yoaA 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGHHMJKG_00492 7.05e-172 yoxB - - - - - - -
PGHHMJKG_00493 8.07e-53 yoxC - - S - - - Bacterial protein of unknown function (DUF948)
PGHHMJKG_00494 3.77e-158 fabG 1.1.1.100 - S ko:K00059,ko:K07124 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_00495 5.37e-79 rtp - - K - - - Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PGHHMJKG_00496 1.07e-54 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGHHMJKG_00497 3.43e-100 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGHHMJKG_00498 2.05e-173 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGHHMJKG_00499 2.61e-205 gltC - - K ko:K09681 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00500 0.0 gltA 1.4.1.13, 1.4.1.14, 1.4.7.1 - E ko:K00265,ko:K00284 ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 glutamate synthase
PGHHMJKG_00501 0.0 gltD 1.4.1.13, 1.4.1.14 - E ko:K00266 ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko01000 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PGHHMJKG_00502 4.18e-237 yogA - - C ko:K13955 - ko00000 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PGHHMJKG_00503 4.34e-201 gltR1 - - K ko:K21959 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00504 0.0 ggt 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PGHHMJKG_00505 3.31e-47 yoeD - - G - - - Helix-turn-helix domain
PGHHMJKG_00506 1.14e-124 - - - L - - - Integrase
PGHHMJKG_00508 8.34e-127 yoeB - - S - - - IseA DL-endopeptidase inhibitor
PGHHMJKG_00509 1.14e-311 yoeA - - V - - - MATE efflux family protein
PGHHMJKG_00510 1.92e-240 yoxA 5.1.3.3 - G ko:K01785 ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Aldose 1-epimerase
PGHHMJKG_00511 0.0 dacC 3.4.16.4 - M ko:K07259 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PGHHMJKG_00512 0.0 - - - Q ko:K15664,ko:K15666,ko:K15667 ko01054,map01054 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHHMJKG_00513 0.0 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
PGHHMJKG_00514 7.8e-49 - 6.3.2.14 - Q ko:K02364,ko:K15656,ko:K15668 ko01053,ko01054,ko01110,ko01130,ko02024,map01053,map01054,map01110,map01130,map02024 ko00000,ko00001,ko01000,ko01008 amino acid activation for nonribosomal peptide biosynthetic process
PGHHMJKG_00515 1.01e-82 yngL - - S - - - Protein of unknown function (DUF1360)
PGHHMJKG_00516 0.0 yngK - - T - - - Glycosyl hydrolase-like 10
PGHHMJKG_00517 3.09e-267 yngJ 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PGHHMJKG_00518 0.0 yngI - - IQ ko:K00666 - ko00000,ko01000,ko01004 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGHHMJKG_00519 5.62e-316 yngH 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Biotin carboxylase
PGHHMJKG_00520 7.15e-43 - - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 Biotin carboxyl carrier protein
PGHHMJKG_00521 1.12e-210 yngG 4.1.3.4 - E ko:K01640 ko00072,ko00280,ko00281,ko00650,ko01100,ko04146,map00072,map00280,map00281,map00650,map01100,map04146 ko00000,ko00001,ko00002,ko01000 Hydroxymethylglutaryl-CoA lyase
PGHHMJKG_00522 4.96e-174 yngF - - I - - - Belongs to the enoyl-CoA hydratase isomerase family
PGHHMJKG_00523 0.0 yngE - - I - - - COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PGHHMJKG_00524 1.74e-294 yngD - - S ko:K07097 - ko00000 phosphohydrolase (DHH superfamily)
PGHHMJKG_00525 1.16e-133 yngC - - S - - - membrane-associated protein
PGHHMJKG_00526 1.07e-207 yngB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PGHHMJKG_00527 1.36e-100 yngA - - S - - - membrane
PGHHMJKG_00528 8.44e-31 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PGHHMJKG_00529 5.7e-309 xynD 3.2.1.55 CBM6,GH43 G ko:K15921 ko00520,map00520 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PGHHMJKG_00530 1.89e-31 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
PGHHMJKG_00531 4.5e-242 ynfF 3.2.1.136 GH5 M ko:K15924 - ko00000,ko01000 Belongs to the glycosyl hydrolase 30 family
PGHHMJKG_00533 0.0 bglC5 3.2.1.4 GH5,GH9 G ko:K01179 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 PFAM glycoside hydrolase family 5
PGHHMJKG_00534 0.0 alsT - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PGHHMJKG_00535 8.74e-75 ynfC - - - - - - -
PGHHMJKG_00536 1.82e-18 - - - - - - - -
PGHHMJKG_00537 0.0 parC - - L ko:K02621 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGHHMJKG_00538 0.0 parE - - L ko:K02622 - ko00000,ko01000,ko02048,ko03032,ko03036 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PGHHMJKG_00539 1.72e-90 yneT - - S ko:K06929 - ko00000 CoA-binding protein
PGHHMJKG_00540 5.48e-122 plsY 2.3.1.15 - I ko:K08591 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PGHHMJKG_00541 8.97e-65 yneR - - S - - - Belongs to the HesB IscA family
PGHHMJKG_00542 3.3e-71 yneQ - - - - - - -
PGHHMJKG_00543 1.15e-94 yneP - - S ko:K07107 - ko00000,ko01000 Thioesterase-like superfamily
PGHHMJKG_00544 6.62e-48 tlp - - S ko:K06434 - ko00000 Belongs to the Tlp family
PGHHMJKG_00546 9.26e-10 - - - S - - - Fur-regulated basic protein B
PGHHMJKG_00547 8.82e-119 yneN - - CO - - - alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PGHHMJKG_00548 0.0 citB 4.2.1.3 - C ko:K01681 ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PGHHMJKG_00549 3.75e-21 sspO - - S ko:K06432 - ko00000 Belongs to the SspO family
PGHHMJKG_00550 5.65e-27 sspP - - S ko:K06433 - ko00000 Belongs to the SspP family
PGHHMJKG_00551 7.02e-86 cotM - - O ko:K06335 - ko00000 Spore coat protein
PGHHMJKG_00552 2.79e-97 yneK - - S - - - Protein of unknown function (DUF2621)
PGHHMJKG_00553 1.87e-96 tagE 2.4.1.52 GT4 M ko:K00712 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PGHHMJKG_00554 8.18e-07 - - - K - - - Cro/C1-type HTH DNA-binding domain
PGHHMJKG_00555 2.45e-34 - - - K - - - Helix-turn-helix domain
PGHHMJKG_00556 1.14e-20 - - - S - - - peptidoglycan catabolic process
PGHHMJKG_00557 7.12e-37 - - - - - - - -
PGHHMJKG_00558 8.25e-61 - - - S - - - Restriction endonuclease
PGHHMJKG_00559 1.33e-160 ynaC - - - - - - -
PGHHMJKG_00560 2.11e-66 - - - S - - - Protein of unknown function (DUF1433)
PGHHMJKG_00561 1.03e-305 - - - I - - - Pfam Lipase (class 3)
PGHHMJKG_00562 9.96e-22 - - - - - - - -
PGHHMJKG_00563 3.86e-10 - - - S - - - Family of unknown function (DUF5316)
PGHHMJKG_00565 8.21e-15 - - - K - - - Transcriptional regulator
PGHHMJKG_00568 4.26e-220 - - - S - - - Alpha/beta hydrolase family
PGHHMJKG_00569 3.77e-149 - - - S ko:K07150 - ko00000 Protein of unknown function (DUF554)
PGHHMJKG_00570 1.23e-188 - - - K - - - Bacterial transcription activator, effector binding domain
PGHHMJKG_00571 2.12e-198 ydfM - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGHHMJKG_00572 7.8e-142 ydfN - - C ko:K15976 - ko00000,ko01000 nitroreductase
PGHHMJKG_00573 1.29e-236 ydfO - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PGHHMJKG_00574 1.28e-61 ydfP - - S ko:K15977 - ko00000 DoxX
PGHHMJKG_00575 2.1e-71 ydfQ - - CO - - - Thioredoxin
PGHHMJKG_00576 2.4e-21 ydgA - - S - - - Spore germination protein gerPA/gerPF
PGHHMJKG_00577 3.75e-39 - - - - - - - -
PGHHMJKG_00579 5e-152 ydfR - - S - - - Protein of unknown function (DUF421)
PGHHMJKG_00580 8.96e-160 ydfS - - S - - - Protein of unknown function (DUF421)
PGHHMJKG_00581 1.28e-98 cotP - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PGHHMJKG_00582 5.54e-50 ydgA - - S - - - Spore germination protein gerPA/gerPF
PGHHMJKG_00583 2.19e-56 ydgB - - S - - - Spore germination protein gerPA/gerPF
PGHHMJKG_00584 2.85e-126 ydgC - - K - - - Bacterial regulatory proteins, tetR family
PGHHMJKG_00585 5.76e-70 - - - S - - - DoxX-like family
PGHHMJKG_00586 8.04e-111 yycN - - K - - - Acetyltransferase
PGHHMJKG_00587 0.0 expZ - - S ko:K18231 ko02010,map02010 br01600,ko00000,ko00001,ko01504,ko02000 ABC transporter
PGHHMJKG_00588 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_00589 6.94e-117 - - - S - - - DinB family
PGHHMJKG_00590 1.19e-103 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PGHHMJKG_00591 0.0 ydgH - - S ko:K06994 - ko00000 drug exporters of the RND superfamily
PGHHMJKG_00592 6.42e-147 ydgI - - C - - - nitroreductase
PGHHMJKG_00593 1.9e-89 - - - K - - - Winged helix DNA-binding domain
PGHHMJKG_00594 9.89e-266 tcaB - - EGP ko:K07552 - ko00000,ko02000 -transporter
PGHHMJKG_00595 1.77e-155 ydhB - - S ko:K07090 - ko00000 membrane transporter protein
PGHHMJKG_00596 1.24e-156 ydhC - - K - - - FCD
PGHHMJKG_00597 5.08e-300 ydhD - - M - - - Glycosyl hydrolase
PGHHMJKG_00598 6.49e-288 ydhE - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PGHHMJKG_00599 4.28e-163 - - - - - - - -
PGHHMJKG_00600 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PGHHMJKG_00601 5.54e-88 frataxin - - S ko:K05937 - ko00000 Domain of unknown function (DU1801)
PGHHMJKG_00603 2.78e-110 - - - K - - - Acetyltransferase (GNAT) domain
PGHHMJKG_00604 5.22e-229 ydhJ - - S ko:K06885 - ko00000 Metal dependent phosphohydrolases with conserved 'HD' motif.
PGHHMJKG_00605 5.93e-130 ydhK - - M - - - Protein of unknown function (DUF1541)
PGHHMJKG_00606 3.64e-254 ydhL - - EGP ko:K18567 - ko00000,ko02000 COG2814 Arabinose efflux permease
PGHHMJKG_00607 2.29e-64 ydhM 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_00608 2.31e-41 ydhN3 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_00609 1.22e-173 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGHHMJKG_00610 1.2e-114 celB - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGHHMJKG_00611 0.0 ydhP 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGHHMJKG_00612 2.22e-170 ydhQ - - K ko:K03492 - ko00000,ko03000 UTRA
PGHHMJKG_00613 3.34e-212 gmuE 2.7.1.4 - GK ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 COG1940 Transcriptional regulator sugar kinase
PGHHMJKG_00614 1.07e-09 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PGHHMJKG_00615 1.24e-76 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PGHHMJKG_00616 3.91e-270 ydhT1 3.2.1.78 GH26 G ko:K01218 ko00051,ko02024,map00051,map02024 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 26 family
PGHHMJKG_00617 9.18e-172 ydhU - - P ko:K07217 - ko00000 Catalase
PGHHMJKG_00620 5.6e-173 - - - L - - - Integrase core domain
PGHHMJKG_00621 7.55e-59 orfX1 - - L - - - Transposase
PGHHMJKG_00622 4.31e-181 pdaB - - G - - - Polysaccharide deacetylase
PGHHMJKG_00623 5.95e-133 kbaA - - S ko:K06349 - ko00000 Involved in the activation of the KinB signaling pathway of sporulation
PGHHMJKG_00624 1.04e-122 gerD - - - ko:K06294 - ko00000 -
PGHHMJKG_00625 1.1e-255 mrp - - D ko:K03593 - ko00000,ko03029,ko03036 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PGHHMJKG_00626 2.22e-170 cwlD 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PGHHMJKG_00627 2.54e-91 ybaK - - S - - - Protein of unknown function (DUF2521)
PGHHMJKG_00628 1.45e-184 ybaJ - - Q - - - Methyltransferase domain
PGHHMJKG_00629 4.28e-84 rpsI - - J ko:K02996 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS9 family
PGHHMJKG_00630 1.13e-102 rplM - - J ko:K02871 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PGHHMJKG_00631 2.51e-181 truA 5.4.99.12 - J ko:K06173 - ko00000,ko01000,ko03016 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PGHHMJKG_00632 4.39e-175 ecfT - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGHHMJKG_00633 2.69e-197 ecfA2 - - P ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGHHMJKG_00634 3.05e-199 ecfA1 - - P ko:K16786 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PGHHMJKG_00635 4.27e-77 rplQ - - J ko:K02879 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L17
PGHHMJKG_00636 7.01e-217 rpoA 2.7.7.6 - K ko:K03040 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGHHMJKG_00637 3.24e-84 rpsK - - J ko:K02948 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PGHHMJKG_00638 1.09e-75 rpsM - - J ko:K02952 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PGHHMJKG_00639 2.45e-19 rpmJ - - J ko:K02919 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL36 family
PGHHMJKG_00640 2.92e-46 infA - - J ko:K02518 - ko00000,ko03012 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PGHHMJKG_00641 2.32e-182 map 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PGHHMJKG_00642 2.51e-157 adk 2.7.4.3 - F ko:K00939 ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PGHHMJKG_00643 5.7e-298 secY - - U ko:K03076 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PGHHMJKG_00644 7.32e-95 rplO - - J ko:K02876 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 binds to the 23S rRNA
PGHHMJKG_00645 1.59e-33 rpmD - - J ko:K02907 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L30
PGHHMJKG_00646 9.16e-111 rpsE - - J ko:K02988 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PGHHMJKG_00647 2.89e-75 rplR - - J ko:K02881 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PGHHMJKG_00648 4.47e-121 rplF - - J ko:K02933 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PGHHMJKG_00649 3.11e-87 rpsH - - J ko:K02994 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PGHHMJKG_00650 1.43e-39 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGHHMJKG_00651 7.72e-122 rplE - - J ko:K02931 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PGHHMJKG_00652 1.43e-67 rplX - - J ko:K02895 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PGHHMJKG_00653 3.62e-79 rplN - - J ko:K02874 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PGHHMJKG_00654 1.64e-52 rpsQ - - J ko:K02961 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PGHHMJKG_00655 1.88e-35 rpmC - - J ko:K02904 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uL29 family
PGHHMJKG_00656 1.96e-98 rplP - - J ko:K02878 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PGHHMJKG_00657 5.9e-152 rpsC - - J ko:K02982 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PGHHMJKG_00658 9.23e-71 rplV - - J ko:K02890 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PGHHMJKG_00659 2.83e-62 rpsS - - J ko:K02965 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PGHHMJKG_00660 2.72e-200 rplB - - J ko:K02886 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PGHHMJKG_00661 3.27e-58 rplW - - J ko:K02892 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PGHHMJKG_00662 7.43e-136 rplD - - J ko:K02926 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the polypeptide exit tunnel
PGHHMJKG_00663 7.2e-144 rplC - - J ko:K02906 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PGHHMJKG_00664 2.58e-65 rpsJ - - J ko:K02946 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Involved in the binding of tRNA to the ribosomes
PGHHMJKG_00665 1.83e-230 ybaC - - S - - - Alpha/beta hydrolase family
PGHHMJKG_00666 1.36e-285 tuf - - J ko:K02358 - ko00000,ko03012,ko03029,ko04147 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PGHHMJKG_00667 0.0 fusA - - J ko:K02355 - ko00000,ko03012,ko03029 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PGHHMJKG_00668 4.85e-107 rpsG - - J ko:K02992 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PGHHMJKG_00669 6.67e-94 rpsL - - J ko:K02950 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PGHHMJKG_00670 1.99e-44 rplGB - - J ko:K07590 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the eukaryotic ribosomal protein eL8 family
PGHHMJKG_00671 0.0 rpoC 2.7.7.6 - K ko:K03046 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGHHMJKG_00672 0.0 rpoB 2.7.7.6 - K ko:K03043 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PGHHMJKG_00673 2.43e-138 rsmC 2.1.1.172 - J ko:K00564 - ko00000,ko01000,ko03009 Methyltransferase
PGHHMJKG_00674 2.84e-64 rplL - - J ko:K02935 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PGHHMJKG_00675 1.64e-103 rplJ - - J ko:K02864 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PGHHMJKG_00676 1.82e-162 rplA - - J ko:K02863 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PGHHMJKG_00677 3.4e-93 rplK - - J ko:K02867 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PGHHMJKG_00678 1.37e-124 nusG - - K ko:K02601 - ko00000,ko03009,ko03021 Participates in transcription elongation, termination and antitermination
PGHHMJKG_00679 2.65e-32 secE - - U ko:K03073 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PGHHMJKG_00680 3.27e-149 sigH - - K ko:K03088,ko:K03091,ko:K12296 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko03000,ko03021 Belongs to the sigma-70 factor family
PGHHMJKG_00681 3.31e-114 yacP - - S ko:K06962 - ko00000 RNA-binding protein containing a PIN domain
PGHHMJKG_00682 8.65e-174 trmH 2.1.1.185 - J ko:K03218 - ko00000,ko01000,ko03009 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGHHMJKG_00683 3.52e-96 mrnC - - J ko:K11145 - ko00000,ko01000,ko03009 Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PGHHMJKG_00684 0.0 cysS 6.1.1.16 - J ko:K01883 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-I aminoacyl-tRNA synthetase family
PGHHMJKG_00685 5.46e-152 cysE 2.3.1.30 - E ko:K00640 ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111 ko00000,ko00001,ko00002,ko01000 Serine acetyltransferase
PGHHMJKG_00686 0.0 gltX 6.1.1.24 - J ko:K09698 ko00970,ko01100,map00970,map01100 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PGHHMJKG_00687 1.82e-112 ispF 2.7.7.60, 4.6.1.12 - I ko:K01770,ko:K12506 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PGHHMJKG_00688 3.02e-161 ispD 2.7.7.60 - I ko:K00991 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PGHHMJKG_00689 2.57e-252 yacL - - S - - - COG4956 Integral membrane protein (PIN domain superfamily)
PGHHMJKG_00690 3.8e-251 disA 2.7.7.85 - L ko:K07067 - ko00000,ko01000 Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PGHHMJKG_00691 0.0 radA - - O ko:K04485 - ko00000,ko03400 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PGHHMJKG_00692 0.0 clpC - - O ko:K03696 ko01100,map01100 ko00000,ko03110 Belongs to the ClpA ClpB family
PGHHMJKG_00693 7.74e-257 mcsB 2.7.14.1 - E ko:K19405 - ko00000,ko01000 Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PGHHMJKG_00694 2.36e-74 mcsA - - S ko:K19411 - ko00000 protein with conserved CXXC pairs
PGHHMJKG_00695 8.72e-100 ctsR - - K ko:K03708 - ko00000,ko03000 Belongs to the CtsR family
PGHHMJKG_00696 2.58e-26 - 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PGHHMJKG_00699 1.55e-235 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
PGHHMJKG_00702 3.96e-182 yvaG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_00703 8.9e-131 - - - K - - - Bacterial regulatory proteins, tetR family
PGHHMJKG_00704 2.04e-70 yvaE - - P ko:K03297 - ko00000,ko02000 Small Multidrug Resistance protein
PGHHMJKG_00705 1.94e-95 yvaD - - S - - - Family of unknown function (DUF5360)
PGHHMJKG_00706 0.0 - - - S - - - Fusaric acid resistance protein-like
PGHHMJKG_00707 7.68e-25 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PGHHMJKG_00708 2.92e-88 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PGHHMJKG_00709 1.99e-247 yvaA 1.1.1.371 - S ko:K16044 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PGHHMJKG_00710 6.89e-65 csoR - - S ko:K21600 - ko00000,ko03000 transcriptional
PGHHMJKG_00711 3.02e-40 copZ - - P ko:K07213 ko04978,map04978 ko00000,ko00001 Copper resistance protein CopZ
PGHHMJKG_00712 0.0 copA 3.6.3.54 - P ko:K17686 ko01524,ko04016,map01524,map04016 ko00000,ko00001,ko01000 P-type ATPase
PGHHMJKG_00713 3.07e-27 - - - K - - - Transcriptional regulator
PGHHMJKG_00724 5.86e-29 pilT - - NU ko:K02669 - ko00000,ko02035,ko02044 PFAM Type II secretion system protein E
PGHHMJKG_00727 8.35e-11 - - - M - - - NlpC P60 family protein
PGHHMJKG_00737 1.63e-06 - - - S - - - SEC-C motif
PGHHMJKG_00738 1.38e-56 - - - L - - - Initiator Replication protein
PGHHMJKG_00739 3.19e-42 - - - - - - - -
PGHHMJKG_00740 1.09e-199 - - - S - - - Domain of unknown function (DUF5068)
PGHHMJKG_00741 5.07e-20 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00742 1e-12 - - - K ko:K07727 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00748 1.25e-77 - - - - - - - -
PGHHMJKG_00757 0.00014 - - - K - - - XRE family transcriptional regulator
PGHHMJKG_00760 3.64e-10 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PGHHMJKG_00761 8.62e-13 - - - K - - - Transcriptional regulator
PGHHMJKG_00762 5.8e-08 - - - - - - - -
PGHHMJKG_00765 7.17e-18 coiA - - S ko:K06198 - ko00000 Competence protein CoiA-like family
PGHHMJKG_00767 9.56e-80 - - - L ko:K07491 - ko00000 Transposase IS200 like
PGHHMJKG_00768 1.87e-218 - - - L - - - TIGRFAM Transposase, IS605 OrfB, C-terminal
PGHHMJKG_00777 2.22e-53 - - - - - - - -
PGHHMJKG_00787 5.23e-85 - - - V ko:K02003,ko:K09810 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PGHHMJKG_00788 2.75e-96 - - - S ko:K02004 - ko00000,ko00002,ko02000 bacteriocin-associated integral membrane protein
PGHHMJKG_00801 1.26e-113 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_00808 6.11e-23 - - - S ko:K07171 - ko00000,ko01000,ko02048 PemK-like, MazF-like toxin of type II toxin-antitoxin system
PGHHMJKG_00809 1.92e-19 - - - V - - - VanZ like family
PGHHMJKG_00811 1.96e-17 - - - - - - - -
PGHHMJKG_00812 1.09e-64 yvrI - - K ko:K03093 - ko00000,ko03021 COG1191 DNA-directed RNA polymerase specialized sigma subunit
PGHHMJKG_00813 1.25e-13 - - - S - - - YvrJ protein family
PGHHMJKG_00814 4.64e-10 - - - - - - - -
PGHHMJKG_00820 1.24e-21 - - - - - - - -
PGHHMJKG_00821 7.26e-146 - - - L - - - Belongs to the 'phage' integrase family
PGHHMJKG_00824 9.03e-142 - - - V ko:K06877,ko:K07451 - ko00000,ko01000,ko02048 HNH endonuclease
PGHHMJKG_00827 1.62e-275 kbl 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PGHHMJKG_00828 1.96e-251 tdh 1.1.1.103 - C ko:K00060 ko00260,map00260 ko00000,ko00001,ko01000 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PGHHMJKG_00829 2.44e-49 spoVS - - S ko:K06416 - ko00000 Stage V sporulation protein S
PGHHMJKG_00830 3.57e-194 ymdB - - S ko:K02029,ko:K02030,ko:K09769 - ko00000,ko00002,ko02000 protein conserved in bacteria
PGHHMJKG_00831 4.25e-306 rny - - S ko:K18682 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 Endoribonuclease that initiates mRNA decay
PGHHMJKG_00832 1.82e-276 pbpX - - V - - - Beta-lactamase
PGHHMJKG_00833 4.7e-239 recA - - L ko:K03553 ko03440,map03440 ko00000,ko00001,ko00002,ko03400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PGHHMJKG_00834 3.71e-300 cinA 3.5.1.42 - S ko:K03742,ko:K03743 ko00760,map00760 ko00000,ko00001,ko01000 Belongs to the CinA family
PGHHMJKG_00835 1.36e-131 pgsA 2.7.8.5 - I ko:K00995 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGHHMJKG_00836 3.56e-176 ymfM - - S ko:K15539 - ko00000 protein conserved in bacteria
PGHHMJKG_00837 3.91e-183 ymfK - - S - - - Protein of unknown function (DUF3388)
PGHHMJKG_00838 5.13e-55 ymfJ - - S - - - Protein of unknown function (DUF3243)
PGHHMJKG_00839 6.33e-168 ymfI 1.1.1.100 - S ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PGHHMJKG_00840 2.37e-309 ymfH - - S - - - zinc protease
PGHHMJKG_00841 9.47e-299 albE - - S - - - Peptidase M16
PGHHMJKG_00842 5.1e-266 ymfD - - EGP ko:K08221 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_00843 1.28e-171 ymfC - - K ko:K03710 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_00844 0.0 ftsK - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PGHHMJKG_00845 4.94e-44 - - - S - - - YlzJ-like protein
PGHHMJKG_00846 5.01e-171 tepA - - OU - - - COG0740 Protease subunit of ATP-dependent Clp proteases
PGHHMJKG_00847 0.0 rnjB - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGHHMJKG_00848 9.08e-201 dapA 4.3.3.7 - E ko:K01714 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PGHHMJKG_00849 4.9e-283 dapG 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PGHHMJKG_00850 4.77e-247 asd 1.2.1.11 - E ko:K00133 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PGHHMJKG_00851 1.36e-139 spoVFB - - H ko:K06411 - ko00000 Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PGHHMJKG_00852 2.16e-207 dpaA - - CH ko:K06410 - ko00000 Dipicolinate synthase subunit A
PGHHMJKG_00853 1.53e-56 ymxH - - S - - - YlmC YmxH family
PGHHMJKG_00854 1.62e-295 mlpA - - S - - - Belongs to the peptidase M16 family
PGHHMJKG_00855 2.4e-231 ylxY - - G - - - Sporulation protein, polysaccharide deacetylase
PGHHMJKG_00856 0.0 pnp 2.7.7.8 - J ko:K00962 ko00230,ko00240,ko03018,map00230,map00240,map03018 ko00000,ko00001,ko00002,ko01000,ko03016,ko03019 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PGHHMJKG_00857 7.11e-57 rpsO - - J ko:K02956 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PGHHMJKG_00858 2.22e-230 ribF 2.7.1.26, 2.7.7.2 - H ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ribF family
PGHHMJKG_00859 1.73e-219 truB 5.4.99.25 - J ko:K03177,ko:K03483 - ko00000,ko01000,ko03000,ko03016 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PGHHMJKG_00860 3.29e-75 rbfA - - J ko:K02834 - ko00000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PGHHMJKG_00861 1.11e-59 ylxP - - S ko:K09764 - ko00000 protein conserved in bacteria
PGHHMJKG_00862 0.0 infB - - J ko:K02519 - ko00000,ko03012,ko03029 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PGHHMJKG_00863 6.16e-63 ylxQ - - J - - - ribosomal protein
PGHHMJKG_00864 2.01e-57 ylxR - - K ko:K07742 - ko00000 nucleic-acid-binding protein implicated in transcription termination
PGHHMJKG_00865 5.49e-261 nusA - - K ko:K02600 - ko00000,ko03009,ko03021 Participates in both transcription termination and antitermination
PGHHMJKG_00866 1.34e-104 rimP - - S ko:K09748 - ko00000,ko03009 Required for maturation of 30S ribosomal subunits
PGHHMJKG_00867 0.0 polC 2.7.7.7 - L ko:K03763 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGHHMJKG_00868 0.0 proS 6.1.1.15 - J ko:K01881 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PGHHMJKG_00869 6.84e-294 rasP - - M ko:K11749 ko02024,ko04112,map02024,map04112 ko00000,ko00001,ko01000,ko01002 zinc metalloprotease
PGHHMJKG_00870 1.14e-275 dxr 1.1.1.267 - I ko:K00099 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PGHHMJKG_00871 4.74e-178 cdsA 2.7.7.41 - S ko:K00981 ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070 ko00000,ko00001,ko00002,ko01000 Belongs to the CDS family
PGHHMJKG_00872 3.84e-187 uppS 2.5.1.31 - I ko:K00806 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PGHHMJKG_00873 9.6e-119 frr - - J ko:K02838 - ko00000,ko03012 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PGHHMJKG_00874 5.82e-163 pyrH 2.7.4.22 - F ko:K09903 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphorylation of UMP to UDP
PGHHMJKG_00875 9.82e-202 tsf - - J ko:K02357 - ko00000,ko03012,ko03029 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PGHHMJKG_00876 1.49e-168 rpsB - - J ko:K02967 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the universal ribosomal protein uS2 family
PGHHMJKG_00877 6.91e-101 ylxL - - - - - - -
PGHHMJKG_00878 6.57e-176 sigD - - K ko:K02405 ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111 ko00000,ko00001,ko02035,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_00879 3.34e-112 cheD 3.5.1.44 - NT ko:K03411 ko02030,map02030 ko00000,ko00001,ko01000,ko02035 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PGHHMJKG_00880 3.42e-142 cheC - - NT ko:K03410 ko02030,map02030 ko00000,ko00001,ko02035 COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PGHHMJKG_00881 1.56e-103 cheW - - NT ko:K03408 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 COG0835 Chemotaxis signal transduction protein
PGHHMJKG_00882 0.0 cheA 2.7.13.3 - NT ko:K03407 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035 COG0643 Chemotaxis protein histidine kinase and related kinases
PGHHMJKG_00883 1.49e-251 cheB 3.1.1.61, 3.5.1.44 - NT ko:K03412 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko01000,ko02022,ko02035 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PGHHMJKG_00884 1.81e-199 ylxH - - D ko:K04562 - ko00000,ko02035 Belongs to the ParA family
PGHHMJKG_00885 8.03e-256 flhF - - N ko:K02404 - ko00000,ko02035 Flagellar biosynthesis regulator FlhF
PGHHMJKG_00886 0.0 flhA - - N ko:K02400 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGHHMJKG_00887 3.89e-244 flhB - - N ko:K02401 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PGHHMJKG_00888 1.47e-170 fliR - - N ko:K02421 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthetic protein FliR
PGHHMJKG_00889 5.23e-50 fliQ - - N ko:K02420 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Role in flagellar biosynthesis
PGHHMJKG_00890 1.21e-141 fliP - - N ko:K02419 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Plays a role in the flagellum-specific transport system
PGHHMJKG_00891 3.99e-130 fliZ - - N ko:K02418 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 Flagellar biosynthesis protein, FliO
PGHHMJKG_00892 1.22e-76 cheY - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 response regulator
PGHHMJKG_00893 1.6e-252 fliY - - N ko:K02417 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035,ko02044 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PGHHMJKG_00894 6.61e-231 fliM - - N ko:K02416 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PGHHMJKG_00895 5.59e-78 fliL - - N ko:K02415 - ko00000,ko02035 Controls the rotational direction of flagella during chemotaxis
PGHHMJKG_00896 3.12e-179 flgG - - N ko:K02390 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod
PGHHMJKG_00897 5.67e-96 flgD - - N ko:K02389 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar basal body rod modification protein
PGHHMJKG_00898 1.36e-306 fliK - - N ko:K02414 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-length control protein
PGHHMJKG_00899 1.02e-83 ylxF - - S - - - MgtE intracellular N domain
PGHHMJKG_00900 1.79e-91 fliJ - - N ko:K02413 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar biosynthesis chaperone
PGHHMJKG_00901 3.5e-307 fliI 3.6.3.14 - NU ko:K02412 ko02040,map02040 ko00000,ko00001,ko01000,ko02035,ko02044 COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PGHHMJKG_00902 4.51e-143 fliH - - NU ko:K02411 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 COG1317 Flagellar biosynthesis type III secretory pathway protein
PGHHMJKG_00903 6.08e-230 fliG - - N ko:K02410 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02035 One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PGHHMJKG_00904 0.0 fliF - - N ko:K02409 ko02040,map02040 ko00000,ko00001,ko02035,ko02044 The M ring may be actively involved in energy transduction
PGHHMJKG_00905 5.5e-53 fliE - - N ko:K02408 ko02040,map02040 ko00000,ko00001,ko02035 Flagellar hook-basal body
PGHHMJKG_00906 2.16e-98 flgC - - N ko:K02388 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the flagella basal body rod proteins family
PGHHMJKG_00907 9.37e-83 flgB - - N ko:K02387 ko02040,map02040 ko00000,ko00001,ko02035 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PGHHMJKG_00908 1.95e-175 codY - - K ko:K03706 - ko00000,ko03000 DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PGHHMJKG_00909 0.0 hslU - - O ko:K03667 - ko00000,ko03110 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PGHHMJKG_00910 3.01e-120 hslV 3.4.25.2 - O ko:K01419 - ko00000,ko01000,ko01002 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PGHHMJKG_00911 6.51e-217 xerC - - L ko:K03733,ko:K04763 - ko00000,ko03036 tyrosine recombinase XerC
PGHHMJKG_00912 2.22e-313 trmFO 2.1.1.74 - J ko:K04094 - ko00000,ko01000,ko03016,ko03036 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PGHHMJKG_00913 0.0 topA 5.99.1.2 - L ko:K03168 - ko00000,ko01000,ko03032,ko03400 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGHHMJKG_00914 3.48e-213 dprA - - LU ko:K04096 - ko00000 Rossmann fold nucleotide-binding protein involved in DNA uptake
PGHHMJKG_00915 1.53e-213 sucD 6.2.1.5 - C ko:K01902 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PGHHMJKG_00916 6.77e-269 sucC 6.2.1.5 - C ko:K01903 ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PGHHMJKG_00917 1.7e-59 ylqH - - S ko:K04061 - ko00000,ko02044 homolog of the cytoplasmic domain of flagellar protein FhlB
PGHHMJKG_00918 0.0 ylqG - - - - - - -
PGHHMJKG_00919 5.83e-175 rnhB 3.1.26.4 - L ko:K03470 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGHHMJKG_00920 5.7e-200 rbgA - - S ko:K14540 - ko00000,ko03009 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PGHHMJKG_00921 8.14e-75 rplS - - J ko:K02884 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PGHHMJKG_00922 1.98e-176 trmD 2.1.1.228 - J ko:K00554 - ko00000,ko01000,ko03016 Belongs to the RNA methyltransferase TrmD family
PGHHMJKG_00923 7.5e-122 rimM - - J ko:K02860 - ko00000,ko03009 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PGHHMJKG_00924 3.41e-80 ylqD - - S - - - YlqD protein
PGHHMJKG_00925 1.2e-49 ylqC - - S ko:K06960 - ko00000 Belongs to the UPF0109 family
PGHHMJKG_00926 1.13e-58 rpsP - - J ko:K02959 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bS16 family
PGHHMJKG_00927 1.13e-307 ffh 3.6.5.4 - U ko:K03106 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko01000,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PGHHMJKG_00928 5.64e-66 ylxM - - S ko:K09787 - ko00000 Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PGHHMJKG_00929 1.67e-114 - - - - - - - -
PGHHMJKG_00930 3.38e-227 ftsY - - U ko:K03110 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PGHHMJKG_00931 0.0 smc - - D ko:K03529 - ko00000,ko03036 Required for chromosome condensation and partitioning
PGHHMJKG_00932 2.12e-174 rnc 3.1.26.3 - J ko:K03685 ko03008,ko05205,map03008,map05205 ko00000,ko00001,ko01000,ko03009,ko03019,ko03036 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PGHHMJKG_00933 1.15e-43 acpP - - IQ ko:K02078 - ko00000,ko00001 Carrier of the growing fatty acid chain in fatty acid biosynthesis
PGHHMJKG_00934 2.88e-166 fabG 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 reductase
PGHHMJKG_00935 4.39e-217 fabD 2.3.1.39 - I ko:K00645,ko:K15327,ko:K15329 ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004,ko01008 malonyl CoA-acyl carrier protein transacylase
PGHHMJKG_00936 1.68e-229 plsX 2.3.1.15 - I ko:K03621 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PGHHMJKG_00937 6.22e-121 fapR - - K - - - Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PGHHMJKG_00938 0.0 recG 3.6.4.12 - L ko:K03655 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PGHHMJKG_00939 1.19e-201 sdaAA 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PGHHMJKG_00940 1.45e-153 sdaAB 4.3.1.17 - E ko:K01752 ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko01000 L-serine dehydratase
PGHHMJKG_00941 0.0 yloV - - S ko:K07030 - ko00000 kinase related to dihydroxyacetone kinase
PGHHMJKG_00942 3.65e-78 yloU - - S - - - protein conserved in bacteria
PGHHMJKG_00943 7.06e-36 rpmB - - J ko:K02902 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL28 family
PGHHMJKG_00944 8.13e-157 thiN 2.7.6.2 - H ko:K00949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 thiamine pyrophosphokinase
PGHHMJKG_00945 4.68e-153 rpe 5.1.3.1 - G ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the ribulose-phosphate 3-epimerase family
PGHHMJKG_00946 1.37e-215 rsgA 3.1.3.100 - S ko:K06949 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03009 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PGHHMJKG_00947 0.0 prkC 2.7.11.1 - KLT ko:K08884,ko:K12132 - ko00000,ko01000,ko01001 serine threonine protein kinase
PGHHMJKG_00948 1.38e-177 stp 3.1.3.16 - T ko:K20074 - ko00000,ko01000,ko01009 phosphatase
PGHHMJKG_00949 2.07e-261 rlmN 2.1.1.192 - J ko:K06941 - ko00000,ko01000,ko03009 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PGHHMJKG_00950 0.0 sun 2.1.1.176 - J ko:K03500 - ko00000,ko01000,ko03009 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PGHHMJKG_00951 4.09e-222 fmt 2.1.2.9 - J ko:K00604 ko00670,ko00970,map00670,map00970 ko00000,ko00001,ko01000 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PGHHMJKG_00952 7.97e-108 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGHHMJKG_00953 0.0 priA - - L ko:K04066 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGHHMJKG_00954 5.13e-286 coaBC 4.1.1.36, 6.3.2.5 - H ko:K01598,ko:K13038 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PGHHMJKG_00955 6.21e-39 rpoZ 2.7.7.6 - K ko:K03060 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PGHHMJKG_00956 5.73e-143 gmk 2.7.4.8 - F ko:K00942 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko00002,ko01000 Essential for recycling GMP and indirectly, cGMP
PGHHMJKG_00957 3.97e-54 ylzA - - S ko:K09777 - ko00000 Belongs to the UPF0296 family
PGHHMJKG_00958 8.41e-202 yloC - - S - - - stress-induced protein
PGHHMJKG_00959 0.0 yloB 3.6.3.8 - P ko:K01537 - ko00000,ko01000 COG0474 Cation transport ATPase
PGHHMJKG_00960 0.0 FbpA - - K - - - RNA-binding protein homologous to eukaryotic snRNP
PGHHMJKG_00961 9.28e-108 sirC 1.3.1.76, 4.99.1.4 - H ko:K02304 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Siroheme synthase
PGHHMJKG_00962 2.06e-187 sirB 4.99.1.4 - S ko:K03794 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sirohydrochlorin ferrochelatase
PGHHMJKG_00963 6.89e-184 cobA 2.1.1.107 - H ko:K02303 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PGHHMJKG_00964 5.56e-142 cysC 2.7.1.25 - P ko:K00860 ko00230,ko00920,ko01100,ko01120,map00230,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of activated sulfate
PGHHMJKG_00965 2.15e-284 sat 2.7.7.4 - P ko:K00958 ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the sulfate adenylyltransferase family
PGHHMJKG_00966 2.1e-229 cysP - - P ko:K16331 - ko00000,ko02000 phosphate transporter
PGHHMJKG_00967 5.95e-182 cysH 1.8.4.10, 1.8.4.8 - EH ko:K00390 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the PAPS reductase family. CysH subfamily
PGHHMJKG_00968 3e-147 pyrE 2.4.2.10 - F ko:K00762 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PGHHMJKG_00969 2.67e-163 pyrF 4.1.1.23 - F ko:K01591 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PGHHMJKG_00970 4.97e-220 pyrD 1.3.1.14 - F ko:K17828 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PGHHMJKG_00971 1.57e-184 pyrK - - C ko:K02823 ko00240,ko01100,map00240,map01100 ko00000,ko00001 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PGHHMJKG_00972 0.0 carB 6.3.5.5 - F ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the CarB family
PGHHMJKG_00973 3.76e-269 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PGHHMJKG_00974 4.86e-316 pyrC 3.5.2.3 - F ko:K01465 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PGHHMJKG_00975 1.04e-213 pyrB 2.1.3.2 - F ko:K00609 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the ATCase OTCase family
PGHHMJKG_00976 1.3e-294 pyrP - - F ko:K02824 - ko00000,ko02000 Xanthine uracil
PGHHMJKG_00977 4.45e-122 pyrR 2.4.2.9 - F ko:K02825 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000,ko03000 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PGHHMJKG_00978 2.38e-223 rluD 5.4.99.23 - J ko:K06180 - ko00000,ko01000,ko03009 Responsible for synthesis of pseudouridine from uracil
PGHHMJKG_00979 3.85e-103 lspA 3.4.23.36 - MU ko:K03101 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PGHHMJKG_00980 9.18e-83 ylyA - - T - - - COG1734 DnaK suppressor protein
PGHHMJKG_00981 6.41e-118 ywjG - - S - - - Domain of unknown function (DUF2529)
PGHHMJKG_00982 1.07e-81 spo0F - - T ko:K02490 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG0784 FOG CheY-like receiver
PGHHMJKG_00983 7.82e-204 fbaA 4.1.2.13, 4.1.2.29 - G ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Aldolase
PGHHMJKG_00984 5.69e-147 tal 2.2.1.2 - G ko:K00616 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PGHHMJKG_00986 2.26e-303 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGHHMJKG_00987 2.03e-224 glpX 3.1.3.11 - G ko:K02446 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 fructose-1,6-bisphosphatase
PGHHMJKG_00988 5.53e-303 rho - - K ko:K03628 ko03018,map03018 ko00000,ko00001,ko03019,ko03021 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PGHHMJKG_00989 7e-45 rpmE - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds the 23S rRNA
PGHHMJKG_00990 9.96e-135 tdk 2.7.1.21 - F ko:K00857 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 thymidine kinase
PGHHMJKG_00991 0.0 ykwA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PGHHMJKG_00992 3.24e-204 ywkB - - S ko:K07088 - ko00000 Membrane transport protein
PGHHMJKG_00993 2.45e-116 racA - - K ko:K11686 - ko00000,ko03036 Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PGHHMJKG_00994 1.19e-89 ywkD - - E ko:K08234 - ko00000 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHHMJKG_00995 9.95e-245 prfA - - J ko:K02835 - ko00000,ko03012 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PGHHMJKG_00996 5.96e-205 prmC 2.1.1.297 - J ko:K02493 - ko00000,ko01000,ko03012 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PGHHMJKG_00998 9.69e-74 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PGHHMJKG_00999 2.29e-152 spoIIR - - S ko:K06387 - ko00000 stage II sporulation protein R
PGHHMJKG_01000 2.55e-100 ywlB - - E - - - Belongs to the acetyltransferase family. ArgA subfamily
PGHHMJKG_01001 2.36e-247 ywlC 2.7.7.87 - J ko:K07566 - ko00000,ko01000,ko03009,ko03016 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PGHHMJKG_01002 6.48e-117 mntP - - P - - - Probably functions as a manganese efflux pump
PGHHMJKG_01003 9.54e-102 ywlE 3.1.3.48, 3.9.1.2 - T ko:K01104,ko:K20201 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGHHMJKG_01004 9.57e-106 rpiB 5.3.1.6 - G ko:K01808 ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Ribose 5-phosphate isomerase
PGHHMJKG_01005 2.49e-123 ywlG - - S - - - Belongs to the UPF0340 family
PGHHMJKG_01006 4.36e-303 glyA 2.1.2.1 - E ko:K00600 ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PGHHMJKG_01007 5.5e-148 upp 2.4.2.9 - F ko:K00761 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PGHHMJKG_01008 1.91e-81 atpI - - S ko:K02116 - ko00000,ko00194 ATP synthase
PGHHMJKG_01009 6.06e-167 atpB - - C ko:K02108 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko03110 it plays a direct role in the translocation of protons across the membrane
PGHHMJKG_01010 3.01e-36 atpE - - C ko:K02110 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGHHMJKG_01011 2.62e-79 atpF - - C ko:K02109 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PGHHMJKG_01012 5.36e-114 atpH - - C ko:K02113 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PGHHMJKG_01013 0.0 atpA 3.6.3.14 - C ko:K02111 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PGHHMJKG_01014 1.28e-194 atpG - - C ko:K02115 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PGHHMJKG_01015 0.0 atpD 3.6.3.14 - C ko:K02112 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194,ko01000 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PGHHMJKG_01016 2.44e-75 atpC - - C ko:K02114 ko00190,ko00195,ko01100,map00190,map00195,map01100 ko00000,ko00001,ko00002,ko00194 Produces ATP from ADP in the presence of a proton gradient across the membrane
PGHHMJKG_01017 2.92e-113 ywmA - - - - - - -
PGHHMJKG_01018 4.54e-45 ywzB - - S - - - membrane
PGHHMJKG_01019 6.59e-172 ywmB - - S - - - TATA-box binding
PGHHMJKG_01020 4.96e-306 murA 2.5.1.7 - M ko:K00790 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PGHHMJKG_01021 3.05e-237 spoIID - - D ko:K06381 - ko00000 Stage II sporulation protein D
PGHHMJKG_01022 5.21e-155 ywmC - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PGHHMJKG_01023 3.4e-154 ywmD - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PGHHMJKG_01025 9.06e-187 fdhD - - C ko:K02379 - ko00000 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PGHHMJKG_01026 1.08e-245 moaA 4.1.99.22 - H ko:K03639 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PGHHMJKG_01027 6.22e-129 rapA - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_01028 8.55e-110 ywmF - - S - - - Peptidase M50
PGHHMJKG_01029 2.15e-19 csbD - - K - - - CsbD-like
PGHHMJKG_01030 0.000282 - - - E ko:K11959 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Receptor family ligand binding region
PGHHMJKG_01031 6.75e-67 ureA 3.5.1.5 - E ko:K01430 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease gamma subunit family
PGHHMJKG_01032 1.12e-83 ureB 3.5.1.5 - E ko:K01429 ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120 ko00000,ko00001,ko01000 Belongs to the urease beta subunit family
PGHHMJKG_01033 0.0 ureC 3.5.1.5 - E ko:K01428 ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PGHHMJKG_01034 4.58e-85 ywnA - - K - - - Transcriptional regulator
PGHHMJKG_01035 6.73e-19 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
PGHHMJKG_01036 1.42e-112 ywnB - - S ko:K07118 - ko00000 NAD(P)H-binding
PGHHMJKG_01037 1.06e-78 ywnC - - S - - - Family of unknown function (DUF5362)
PGHHMJKG_01038 1.28e-179 mta - - K ko:K21743 - ko00000,ko03000 transcriptional
PGHHMJKG_01039 0.0 ywnE - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PGHHMJKG_01040 1.05e-91 ywnF - - S - - - Family of unknown function (DUF5392)
PGHHMJKG_01041 6.7e-234 - - - M - - - NeuB family
PGHHMJKG_01042 5.63e-17 ywnC - - S - - - Family of unknown function (DUF5362)
PGHHMJKG_01043 2.12e-114 ywnH 2.3.1.183 - M ko:K03823 ko00440,ko01130,map00440,map01130 ko00000,ko00001,ko01000 COG1247 Sortase and related acyltransferases
PGHHMJKG_01044 1.85e-161 spoIIQ - - M ko:K06386 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PGHHMJKG_01045 9.05e-93 ywnJ - - S - - - VanZ like family
PGHHMJKG_01046 6.02e-135 bcrC 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 COG0671 Membrane-associated phospholipid phosphatase
PGHHMJKG_01047 4.51e-77 nrgB - - K ko:K04751 ko02020,map02020 ko00000,ko00001 Belongs to the P(II) protein family
PGHHMJKG_01048 3.76e-287 nrgA - - P ko:K03320 - ko00000,ko02000 Ammonium transporter
PGHHMJKG_01049 7.16e-101 - - - - - - - -
PGHHMJKG_01050 1.04e-133 yjgF - - Q - - - Isochorismatase family
PGHHMJKG_01051 8.92e-306 ywoD - - EGP - - - Major facilitator superfamily
PGHHMJKG_01052 0.0 - - - FH ko:K03457,ko:K10975 - ko00000,ko02000 COG1953 Cytosine uracil thiamine allantoin permeases
PGHHMJKG_01053 3.25e-309 ywoF - - P - - - Right handed beta helix region
PGHHMJKG_01054 1.37e-269 ywoG - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_01055 8.45e-92 - - - K - - - COG1846 Transcriptional regulators
PGHHMJKG_01056 4.88e-59 spoIIID - - K ko:K06283 - ko00000,ko03000 Stage III sporulation protein D
PGHHMJKG_01057 1.75e-231 mbl - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein
PGHHMJKG_01058 9.37e-168 flhO - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PGHHMJKG_01059 1.17e-181 flhP - - N ko:K02392 ko02040,map02040 ko00000,ko00001,ko02035 flagellar basal body
PGHHMJKG_01060 1.5e-254 rapD - - S ko:K06362 - ko00000,ko01000 aspartate phosphatase
PGHHMJKG_01061 6.89e-107 fabZ 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PGHHMJKG_01062 7.66e-76 mscL - - M ko:K03282 - ko00000,ko02000 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PGHHMJKG_01063 4.66e-186 ywpD - - T - - - Histidine kinase
PGHHMJKG_01064 3.81e-67 srtA 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 Sortase family
PGHHMJKG_01065 3.59e-88 ywpF - - S - - - YwpF-like protein
PGHHMJKG_01066 2.79e-40 ywpG - - - - - - -
PGHHMJKG_01067 4.23e-76 ssbB - - L ko:K03111 ko03030,ko03430,ko03440,map03030,map03430,map03440 ko00000,ko00001,ko03029,ko03032,ko03400 Single-stranded DNA-binding protein
PGHHMJKG_01068 4.82e-180 glcR - - K ko:K22103 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PGHHMJKG_01069 3.57e-200 ywpJ 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PGHHMJKG_01070 0.0 ywqA - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PGHHMJKG_01071 0.0 ywqB - - S - - - SWIM zinc finger
PGHHMJKG_01072 3.6e-25 - - - - - - - -
PGHHMJKG_01073 5.33e-163 ywqC - - M ko:K19420 - ko00000 biosynthesis protein
PGHHMJKG_01074 1.06e-152 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PGHHMJKG_01075 5.03e-180 ywqE 3.1.3.48 - GM ko:K01104 - ko00000,ko01000 COG4464 Capsular polysaccharide biosynthesis protein
PGHHMJKG_01076 6.34e-311 ywqF 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PGHHMJKG_01077 9.48e-193 ywqG - - S - - - Domain of unknown function (DUF1963)
PGHHMJKG_01079 8.84e-52 ywqI - - S - - - Family of unknown function (DUF5344)
PGHHMJKG_01080 3.15e-265 - - - L - - - nucleic acid phosphodiester bond hydrolysis
PGHHMJKG_01081 2.5e-26 - - - - - - - -
PGHHMJKG_01082 1.3e-23 - - - - - - - -
PGHHMJKG_01083 4.93e-95 ywqJ - - S - - - Pre-toxin TG
PGHHMJKG_01084 9.77e-48 - - - S ko:K11904,ko:K21493 ko03070,map03070 ko00000,ko00001,ko00002,ko01000,ko02044,ko02048 protein secretion by the type VII secretion system
PGHHMJKG_01086 2.88e-147 nfi 3.1.21.7 - L ko:K05982 - ko00000,ko01000,ko03400 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PGHHMJKG_01087 4.73e-209 - - - K - - - Transcriptional regulator
PGHHMJKG_01088 1.44e-127 ywqN - - S - - - NAD(P)H-dependent
PGHHMJKG_01090 1.01e-112 ywrA - - P ko:K07240 - ko00000,ko02000 COG2059 Chromate transport protein ChrA
PGHHMJKG_01091 6.44e-132 ywrB - - P ko:K07240 - ko00000,ko02000 Chromate transporter
PGHHMJKG_01092 2.79e-107 ywrC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PGHHMJKG_01093 0.0 ywrD 2.3.2.2, 3.4.19.13 - E ko:K00681 ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100 ko00000,ko00001,ko01000,ko01002 gamma-glutamyltransferase
PGHHMJKG_01094 2.78e-71 - - - S - - - Domain of unknown function (DUF4181)
PGHHMJKG_01095 5.08e-142 ywrF - - S - - - COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PGHHMJKG_01096 1e-17 - - - - - - - -
PGHHMJKG_01097 8.48e-265 cotH - - M ko:K06330 - ko00000 Spore Coat
PGHHMJKG_01098 3.02e-44 cotB - - - ko:K06325 - ko00000 -
PGHHMJKG_01099 1.06e-162 ywrJ - - - - - - -
PGHHMJKG_01100 8.01e-263 ywrK - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PGHHMJKG_01101 3.36e-218 alsR - - K - - - LysR substrate binding domain
PGHHMJKG_01102 0.0 alsS 2.2.1.6 - EH ko:K01652 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TPP enzyme family
PGHHMJKG_01103 1.51e-186 budA 4.1.1.5 - H ko:K01575 ko00650,ko00660,map00650,map00660 ko00000,ko00001,ko01000 Alpha-acetolactate decarboxylase
PGHHMJKG_01104 1.24e-125 ywrO - - S - - - NADPH-quinone reductase (modulator of drug activity B)
PGHHMJKG_01105 3.75e-63 ywsA - - S - - - Protein of unknown function (DUF3892)
PGHHMJKG_01106 1.14e-118 batE - - T - - - Sh3 type 3 domain protein
PGHHMJKG_01107 2.59e-203 rbsB - - G ko:K10439 ko02010,ko02030,map02010,map02030 ko00000,ko00001,ko00002,ko02000 COG1879 ABC-type sugar transport system, periplasmic component
PGHHMJKG_01108 3.35e-203 rbsC - - G ko:K10440 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family
PGHHMJKG_01109 0.0 rbsA 3.6.3.17 - G ko:K10441 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PGHHMJKG_01110 3.12e-82 rbsD 5.4.99.62 - G ko:K06726 ko02010,map02010 ko00000,ko00001,ko01000 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PGHHMJKG_01111 8.06e-201 rbsK 2.7.1.15 - H ko:K00852 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PGHHMJKG_01112 5.85e-225 rbsR - - K ko:K02529 - ko00000,ko03000 transcriptional
PGHHMJKG_01113 0.0 ytcJ - - S - - - amidohydrolase
PGHHMJKG_01114 0.0 ytcI 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PGHHMJKG_01115 5.88e-38 - - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PGHHMJKG_01116 2.55e-288 thiI 2.8.1.4 - H ko:K03151 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PGHHMJKG_01117 1.59e-265 iscS2 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PGHHMJKG_01118 1.17e-304 braB - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PGHHMJKG_01119 0.0 ezrA - - D ko:K06286 - ko00000,ko03036 modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PGHHMJKG_01120 1.07e-197 hisK 3.1.3.15 - E ko:K04486 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PGHHMJKG_01121 9.83e-141 yttP - - K - - - Transcriptional regulator
PGHHMJKG_01122 1.95e-114 ytsP 1.8.4.14 - T ko:K08968 ko00270,map00270 ko00000,ko00001,ko01000 GAF domain-containing protein
PGHHMJKG_01123 0.0 ytrP - - T - - - COG2199 FOG GGDEF domain
PGHHMJKG_01124 2.01e-141 rpsD - - J ko:K02986 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PGHHMJKG_01126 5.31e-303 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGHHMJKG_01127 0.0 acsA 6.2.1.1 - I ko:K01895 ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000,ko01004 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PGHHMJKG_01128 3.46e-156 acuA - - K ko:K04766 - ko00000,ko01000 Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PGHHMJKG_01129 1.45e-150 acuB - - S ko:K04767 - ko00000 Domain in cystathionine beta-synthase and other proteins.
PGHHMJKG_01130 2.58e-290 acuC - - BQ ko:K04768 - ko00000 histone deacetylase
PGHHMJKG_01131 1.6e-161 ytxE - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PGHHMJKG_01132 1.18e-187 motP - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PGHHMJKG_01133 4.16e-235 ccpA - - K ko:K02529 - ko00000,ko03000 catabolite control protein A
PGHHMJKG_01134 7.64e-250 aroA 2.5.1.54, 5.4.99.5 - E ko:K03856,ko:K13853 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PGHHMJKG_01135 6.39e-71 ytxJ - - O - - - Protein of unknown function (DUF2847)
PGHHMJKG_01136 3.17e-30 ytxH - - S - - - COG4980 Gas vesicle protein
PGHHMJKG_01137 1.67e-63 ytxG - - S - - - protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PGHHMJKG_01138 0.0 murC 6.3.2.8 - M ko:K01924 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Belongs to the MurCDEF family
PGHHMJKG_01139 0.0 sftA - - D ko:K03466 - ko00000,ko03036 Belongs to the FtsK SpoIIIE SftA family
PGHHMJKG_01140 7.25e-140 ytpR - - J ko:K06878 - ko00000 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGHHMJKG_01141 1.02e-191 ytpQ - - S - - - Belongs to the UPF0354 family
PGHHMJKG_01142 3.17e-75 ytpP - - CO - - - Thioredoxin
PGHHMJKG_01143 4.89e-63 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
PGHHMJKG_01144 4.88e-29 ytoQ - - S - - - Nucleoside 2-deoxyribosyltransferase YtoQ
PGHHMJKG_01145 3.71e-261 pepA 3.4.11.7 - G ko:K01261,ko:K01269 - ko00000,ko01000,ko01002 COG1363 Cellulase M and related proteins
PGHHMJKG_01146 1.17e-67 ytzB - - S - - - small secreted protein
PGHHMJKG_01147 0.0 malS 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PGHHMJKG_01148 3.05e-190 ytnP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PGHHMJKG_01149 2.52e-155 trmB 2.1.1.33 - J ko:K03439 - ko00000,ko01000,ko03016 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PGHHMJKG_01150 9.51e-61 ytzH - - S - - - YtzH-like protein
PGHHMJKG_01151 3.02e-192 ytmP - - M - - - Phosphotransferase
PGHHMJKG_01152 0.0 amyX 3.2.1.41 CBM48,GH13 G ko:K01200 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 13 family
PGHHMJKG_01153 2.22e-231 ytlR - - I - - - Diacylglycerol kinase catalytic domain
PGHHMJKG_01154 9.92e-212 ytlQ - - - - - - -
PGHHMJKG_01155 1.5e-130 ytlP 3.1.4.58 - J ko:K01975 - ko00000,ko01000,ko03016 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PGHHMJKG_01156 6.05e-221 ytkP 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PGHHMJKG_01157 0.0 ytjP 3.5.1.18 - E ko:K01439 ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Dipeptidase
PGHHMJKG_01158 7.02e-288 pbuO - - S ko:K06901 - ko00000,ko02000 permease
PGHHMJKG_01159 1.12e-252 ythQ - - U ko:K01992 - ko00000,ko00002,ko02000 Bacterial ABC transporter protein EcsB
PGHHMJKG_01160 8.04e-168 ythP - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PGHHMJKG_01161 4.46e-46 ytzE - - K - - - COG1349 Transcriptional regulators of sugar metabolism
PGHHMJKG_01162 7.43e-170 rsuA 5.4.99.19 - J ko:K06183 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PGHHMJKG_01163 0.0 ytgP - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGHHMJKG_01164 6.99e-294 ytfP - - S ko:K07007 - ko00000 HI0933-like protein
PGHHMJKG_01165 0.0 opuD - - M ko:K05020 - ko00000,ko02000 Belongs to the BCCT transporter (TC 2.A.15) family
PGHHMJKG_01166 2.14e-36 yteV - - S - - - Sporulation protein Cse60
PGHHMJKG_01168 6.02e-315 yteT - - S - - - Oxidoreductase family, C-terminal alpha/beta domain
PGHHMJKG_01169 9.64e-94 yteS - - G - - - transport
PGHHMJKG_01170 8.3e-279 yteR 3.2.1.172 GH105 G ko:K15532 - ko00000,ko01000 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
PGHHMJKG_01171 5.35e-220 lplB13 - - G ko:K17319 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4209 ABC-type polysaccharide transport system, permease component
PGHHMJKG_01172 1.36e-202 ytdP - - K - - - Transcriptional regulator
PGHHMJKG_01173 2.13e-75 ytdP - - K - - - Transcriptional regulator
PGHHMJKG_01174 1.13e-165 ytdP - - K - - - Transcriptional regulator
PGHHMJKG_01175 0.0 - - - G ko:K17318 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PGHHMJKG_01176 1.19e-190 ytcP - - G ko:K17320 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PGHHMJKG_01177 2.21e-178 ytbQ 1.1.1.203, 1.1.1.388 - GM ko:K18981,ko:K19243 ko00030,ko00053,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00053,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 NAD dependent epimerase/dehydratase family
PGHHMJKG_01178 2.6e-278 bioI 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PGHHMJKG_01179 2.64e-243 bioB 2.8.1.6 - H ko:K01012 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PGHHMJKG_01180 2.68e-159 bioD 6.3.3.3 - H ko:K01935 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PGHHMJKG_01181 4.1e-272 bioF 2.3.1.29, 2.3.1.47 - H ko:K00639,ko:K00652 ko00260,ko00780,ko01100,map00260,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PGHHMJKG_01182 0.0 bioA 2.6.1.105, 2.6.1.62 - H ko:K00833,ko:K19563 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PGHHMJKG_01183 3.63e-151 bioW 6.2.1.14 - H ko:K01906 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PGHHMJKG_01184 4.8e-221 - - - S - - - Acetyl xylan esterase (AXE1)
PGHHMJKG_01185 4.37e-242 msmR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01186 7.92e-307 msmE - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Bacterial extracellular solute-binding protein
PGHHMJKG_01187 1.66e-214 amyD - - P ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGHHMJKG_01188 7.65e-186 amyC - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PGHHMJKG_01189 0.0 melA 3.2.1.22 - G ko:K07406 ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603 ko00000,ko00001,ko01000 Family 4 glycosyl hydrolase
PGHHMJKG_01190 1.22e-68 ytwF - - P - - - Sulfurtransferase
PGHHMJKG_01191 0.0 leuS 6.1.1.4 - J ko:K01869 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Belongs to the class-I aminoacyl-tRNA synthetase family
PGHHMJKG_01192 3.63e-72 ytvB - - S - - - Protein of unknown function (DUF4257)
PGHHMJKG_01193 3.82e-183 pfyP - - T - - - Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PGHHMJKG_01194 1.21e-268 yttB - - EGP - - - Major facilitator superfamily
PGHHMJKG_01195 5.71e-41 yttA - - S - - - Pfam Transposase IS66
PGHHMJKG_01196 0.0 bceB - - V ko:K11632,ko:K19080 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter (permease)
PGHHMJKG_01197 3.83e-179 bceA - - V ko:K02003,ko:K11631,ko:K19079 ko01503,ko02010,ko02020,ko05150,map01503,map02010,map02020,map05150 ko00000,ko00001,ko00002,ko01504,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01198 4.53e-239 bceS 2.7.13.3 - T ko:K11629,ko:K19077 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022 His Kinase A (phosphoacceptor) domain
PGHHMJKG_01199 2.23e-167 graR - - T ko:K11630,ko:K19078 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01504,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_01200 3.99e-296 ytrF - - V ko:K02004,ko:K16918 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PGHHMJKG_01201 5.88e-163 ytrE - - V ko:K16920 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01202 1.37e-192 - - - - ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 -
PGHHMJKG_01203 4.46e-211 - - - P ko:K16919 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PGHHMJKG_01204 5.96e-207 ytrB - - P ko:K16921 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01205 2.68e-87 ytrA - - K ko:K07979 - ko00000,ko03000 GntR family transcriptional regulator
PGHHMJKG_01208 6.48e-288 brnQ - - E ko:K03311 - ko00000 Component of the transport system for branched-chain amino acids
PGHHMJKG_01209 1.97e-66 azlD - - E - - - Branched-chain amino acid transport protein (AzlD)
PGHHMJKG_01210 9.34e-176 azlC - - E - - - AzlC protein
PGHHMJKG_01211 4.82e-103 bkdR - - K - - - helix_turn_helix ASNC type
PGHHMJKG_01212 2.76e-55 yrdF - - K ko:K03623 - ko00000 ribonuclease inhibitor
PGHHMJKG_01213 1.74e-131 yrdC - - Q - - - Isochorismatase family
PGHHMJKG_01214 3.24e-75 - - - S - - - Protein of unknown function (DUF2568)
PGHHMJKG_01215 2.01e-118 yrdA - - S - - - DinB family
PGHHMJKG_01216 3.9e-210 aadK - - G ko:K05593 - ko00000,ko01000,ko01504 Streptomycin adenylyltransferase
PGHHMJKG_01217 2.45e-245 npd 1.13.12.16 - S ko:K00459 ko00910,map00910 ko00000,ko00001,ko01000 COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PGHHMJKG_01218 9.78e-188 murI 5.1.1.3 - M ko:K01776 ko00471,ko01100,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PGHHMJKG_01219 2.39e-162 yrpD - - S - - - Domain of unknown function, YrpD
PGHHMJKG_01221 4.22e-164 zinT - - S ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
PGHHMJKG_01222 2.5e-121 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_01223 4.9e-239 yrpG - - C - - - Aldo/keto reductase family
PGHHMJKG_01224 2.2e-193 csn 3.2.1.132 - M ko:K01233 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PGHHMJKG_01225 6.15e-57 yraL - - S - - - COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_01226 1.19e-191 - - - S - - - Alpha beta hydrolase
PGHHMJKG_01227 6.61e-80 - - - T - - - sh3 domain protein
PGHHMJKG_01228 2.92e-81 - - - T - - - sh3 domain protein
PGHHMJKG_01229 6.62e-87 - - - E - - - Glyoxalase-like domain
PGHHMJKG_01230 4.19e-50 yraG - - - ko:K06440 - ko00000 -
PGHHMJKG_01231 9.61e-84 yraF - - M - - - Spore coat protein
PGHHMJKG_01232 9.1e-284 adhB 1.1.1.1, 1.1.1.284, 1.2.1.46 - E ko:K00121,ko:K00148 ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204 ko00000,ko00001,ko01000 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PGHHMJKG_01233 6.11e-36 yraE - - - ko:K06440 - ko00000 -
PGHHMJKG_01234 7.23e-66 yraD - - M ko:K06439 - ko00000 Spore coat protein
PGHHMJKG_01235 1.83e-67 adhR - - K ko:K21745 - ko00000,ko03000 helix_turn_helix, mercury resistance
PGHHMJKG_01236 1.76e-39 yphJ 4.1.1.44 - S ko:K01607 ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220 ko00000,ko00001,ko01000 peroxiredoxin activity
PGHHMJKG_01237 4.81e-253 adhA - - C ko:K13979 - ko00000,ko01000 alcohol dehydrogenase
PGHHMJKG_01238 1.58e-116 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PGHHMJKG_01239 0.0 sacC 3.2.1.80 - G ko:K03332 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PGHHMJKG_01240 1.39e-192 levG - - G ko:K02771,ko:K02796 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
PGHHMJKG_01241 1.75e-167 levF - - G ko:K02746,ko:K02795,ko:K11196 ko00051,ko00052,ko00520,ko01100,ko02060,map00051,map00052,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko02000 COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
PGHHMJKG_01242 4.41e-106 ptnA 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11195 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system mannose fructose sorbose family
PGHHMJKG_01243 4.41e-96 levD 2.7.1.191, 2.7.1.202 - G ko:K02793,ko:K02794,ko:K11194 ko00051,ko00520,ko01100,ko02060,map00051,map00520,map01100,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 PTS system fructose IIA component
PGHHMJKG_01244 0.0 levR - - K - - - PTS system fructose IIA component
PGHHMJKG_01245 0.0 aapA - - E ko:K03293,ko:K11737 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_01246 5.63e-137 yrhP - - E - - - LysE type translocator
PGHHMJKG_01247 3.41e-193 yrhO - - K - - - Archaeal transcriptional regulator TrmB
PGHHMJKG_01248 2.35e-112 sigV - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_01249 3.51e-191 rsiV - - S - - - Protein of unknown function (DUF3298)
PGHHMJKG_01250 2.18e-84 oatA - - I - - - Acyltransferase family
PGHHMJKG_01251 0.0 oatA - - I - - - Acyltransferase family
PGHHMJKG_01252 2.58e-58 yrhK - - S - - - YrhK-like protein
PGHHMJKG_01253 0.0 yrhJ 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PGHHMJKG_01254 2.26e-135 - - - K ko:K22106 - ko00000,ko03000 Tetracycline repressor, C-terminal all-alpha domain
PGHHMJKG_01255 4.3e-124 yrhH - - Q - - - methyltransferase
PGHHMJKG_01256 9.39e-08 - - - S - - - Probable sporulation protein (Bac_small_yrzI)
PGHHMJKG_01257 1.13e-182 yrhG - - P ko:K21993 - ko00000,ko02000 Formate nitrite
PGHHMJKG_01259 4.41e-80 yrhF - - S - - - Uncharacterized conserved protein (DUF2294)
PGHHMJKG_01260 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
PGHHMJKG_01261 2.46e-102 yrhD - - S - - - Protein of unknown function (DUF1641)
PGHHMJKG_01262 5.71e-48 yrhC - - S - - - YrhC-like protein
PGHHMJKG_01263 8.55e-269 mccB 4.4.1.1, 4.4.1.2, 4.4.1.8 - E ko:K01760,ko:K17217 ko00260,ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00260,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PGHHMJKG_01264 1.66e-216 mccA 2.5.1.134, 2.5.1.47 - E ko:K01738,ko:K17216 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Cysteine synthase
PGHHMJKG_01265 3.26e-160 mtnN 3.2.2.9 - E ko:K01243 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PGHHMJKG_01266 9.86e-153 yrrT - - Q ko:K17462 ko00270,ko01100,ko01230,map00270,map01100,map01230 ko00000,ko00001,ko00002,ko01000 Could be a S-adenosyl-L-methionine-dependent methyltransferase
PGHHMJKG_01267 4.94e-36 yrzA - - S - - - Protein of unknown function (DUF2536)
PGHHMJKG_01268 2.02e-102 yrrS - - S - - - Protein of unknown function (DUF1510)
PGHHMJKG_01269 0.0 pbpI - - M ko:K21468 - ko00000,ko01011 Penicillin-binding Protein
PGHHMJKG_01270 1.14e-101 greA - - K ko:K03624 - ko00000,ko03021 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PGHHMJKG_01271 4.51e-148 udk 2.7.1.48 - F ko:K00876 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 Cytidine monophosphokinase
PGHHMJKG_01272 4.62e-313 yrrO - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 COG0826 Collagenase and related proteases
PGHHMJKG_01273 2.57e-221 yrrN - - O ko:K08303 ko05120,map05120 ko00000,ko00001,ko01000,ko01002 Peptidase U32
PGHHMJKG_01274 6.92e-155 yrrM 2.1.1.104 - S ko:K00588 ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110 ko00000,ko00001,ko00002,ko01000 O-methyltransferase
PGHHMJKG_01275 6.17e-241 mltG - - S ko:K07082 - ko00000 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PGHHMJKG_01276 2.94e-60 yrzB - - S - - - Belongs to the UPF0473 family
PGHHMJKG_01277 5.49e-93 yrrK - - L ko:K07447 - ko00000,ko01000 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PGHHMJKG_01278 2.22e-55 yrzL - - S - - - Belongs to the UPF0297 family
PGHHMJKG_01279 0.0 alaS 6.1.1.7 - J ko:K01872 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PGHHMJKG_01280 1.25e-241 yrrI - - S - - - AI-2E family transporter
PGHHMJKG_01281 2.21e-168 glnQ - - E ko:K09972,ko:K10041 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PGHHMJKG_01282 3.93e-182 glnH - - ET ko:K09969,ko:K10039 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PGHHMJKG_01283 1.54e-137 glnM - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGHHMJKG_01284 9.26e-140 glnP - - P ko:K10040 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGHHMJKG_01286 2.29e-188 yxkD - - S - - - Uncharacterised 5xTM membrane BCR, YitT family COG1284
PGHHMJKG_01287 0.0 aldY 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGHHMJKG_01288 7.85e-210 lrp - - QT - - - PucR C-terminal helix-turn-helix domain
PGHHMJKG_01289 3.44e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_01290 1.77e-197 yxkH - - G - - - Polysaccharide deacetylase
PGHHMJKG_01292 0.0 - - - O - - - Peptidase family M48
PGHHMJKG_01293 1.09e-307 cimH - - C - - - COG3493 Na citrate symporter
PGHHMJKG_01294 0.0 cydA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PGHHMJKG_01295 1.16e-243 cydB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 Cytochrome d ubiquinol oxidase, subunit II
PGHHMJKG_01296 0.0 cydC - - V ko:K16013 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding
PGHHMJKG_01297 0.0 cydD - - V ko:K16012 ko02010,map02010 ko00000,ko00001,ko02000 ATP-binding protein
PGHHMJKG_01298 3.73e-202 nnrD 4.2.1.136, 5.1.99.6 - G ko:K17758,ko:K17759 - ko00000,ko01000 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PGHHMJKG_01299 0.0 yxlA - - F ko:K03457 - ko00000 Belongs to the purine-cytosine permease (2.A.39) family
PGHHMJKG_01300 2.6e-124 sigY - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_01301 1.93e-62 yxlC - - S - - - Family of unknown function (DUF5345)
PGHHMJKG_01302 1.63e-39 - - - - - - - -
PGHHMJKG_01303 2.17e-39 yxlE - - S - - - Phospholipase_D-nuclease N-terminal
PGHHMJKG_01304 3.33e-210 yxlF - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01305 1.14e-178 yxlG - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PGHHMJKG_01306 3.52e-274 yxlH - - EGP - - - Major Facilitator Superfamily
PGHHMJKG_01307 0.0 katX 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PGHHMJKG_01308 3.23e-145 yxlJ 3.2.2.21 - L ko:K03652 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Belongs to the DNA glycosylase MPG family
PGHHMJKG_01309 1.05e-26 yxzF - - - - - - -
PGHHMJKG_01310 0.0 licR - - GKT ko:K03491 - ko00000,ko03000 Mga helix-turn-helix domain
PGHHMJKG_01311 1.89e-67 licB 2.7.1.196, 2.7.1.205 - G ko:K02760 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 transporter subunit IIB
PGHHMJKG_01312 0.0 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGHHMJKG_01313 8.33e-68 licA 2.7.1.196, 2.7.1.205 - G ko:K02759 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_01314 0.0 licH 3.2.1.86 GT4 G ko:K01222 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PGHHMJKG_01315 1.07e-263 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PGHHMJKG_01316 3.56e-43 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_01317 2.19e-07 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_01318 1.5e-60 dltE - - M ko:K14189 - ko00000,ko01000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_01319 4.09e-294 dltD - - M ko:K03740 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PGHHMJKG_01320 6.83e-50 dltC 6.1.1.13 - IQ ko:K14188 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHHMJKG_01321 1.14e-297 dltB - - M ko:K03739 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01504 membrane protein involved in D-alanine export
PGHHMJKG_01322 0.0 dltA 6.1.1.13 - Q ko:K03367 ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHHMJKG_01324 5.95e-212 menA 2.5.1.74 - H ko:K02548 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the MenA family. Type 1 subfamily
PGHHMJKG_01325 8.23e-39 - - - - - - - -
PGHHMJKG_01326 4.78e-32 - - - - - - - -
PGHHMJKG_01327 3.02e-117 - - - L - - - Replication protein
PGHHMJKG_01328 1.02e-27 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PGHHMJKG_01329 9.8e-22 - - - - - - - -
PGHHMJKG_01330 6.22e-224 - - - L - - - Replication protein
PGHHMJKG_01331 1.12e-154 rapE - - S ko:K06363 ko02024,map02024 ko00000,ko00001,ko01000 Tetratricopeptide repeat
PGHHMJKG_01334 6.29e-100 - - - K - - - Transcriptional regulator
PGHHMJKG_01335 9.8e-302 pre - - D - - - plasmid recombination enzyme
PGHHMJKG_01336 2.82e-122 yhjH - - K - - - helix_turn_helix multiple antibiotic resistance protein
PGHHMJKG_01337 0.0 yhjG - - CH - - - FAD binding domain
PGHHMJKG_01338 3.09e-118 spsB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PGHHMJKG_01339 2.82e-140 yhjE - - S - - - SNARE associated Golgi protein
PGHHMJKG_01340 4.13e-78 yhjD - - - - - - -
PGHHMJKG_01341 1.61e-36 yhjC - - S - - - Protein of unknown function (DUF3311)
PGHHMJKG_01342 0.0 yhjB - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGHHMJKG_01343 4.64e-53 yhjA - - S - - - Excalibur calcium-binding domain
PGHHMJKG_01344 6.46e-210 yhxD - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PGHHMJKG_01345 2.19e-141 comK - - K ko:K02250 ko02024,map02024 ko00000,ko00001,ko02044,ko03000 Competence transcription factor
PGHHMJKG_01346 9.84e-45 yhzC - - S - - - IDEAL
PGHHMJKG_01347 3.72e-202 yhxC - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_01348 3.74e-37 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PGHHMJKG_01349 4.28e-149 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PGHHMJKG_01350 1.18e-120 yhfW - - CE - - - COG0665 Glycine D-amino acid oxidases (deaminating)
PGHHMJKG_01351 6.15e-259 hemAT - - NT ko:K06595 - ko00000,ko02035 chemotaxis protein
PGHHMJKG_01352 1.47e-118 bioY - - S ko:K03523 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 BioY family
PGHHMJKG_01353 0.0 vraA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PGHHMJKG_01354 6.04e-250 yhfS 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PGHHMJKG_01355 9.64e-141 yhfR 5.4.2.12 - G ko:K15634,ko:K15640 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the phosphoglycerate mutase family
PGHHMJKG_01356 5.68e-156 - 4.2.2.10, 4.2.2.2 - G ko:K19551 ko00040,map00040 ko00000,ko00001,ko01000 Pectate lyase
PGHHMJKG_01357 4.31e-179 yvpB - - NU - - - protein conserved in bacteria
PGHHMJKG_01358 2.42e-281 hisZ - - E ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PGHHMJKG_01359 1.06e-147 hisG 2.4.2.17 - E ko:K00765,ko:K02502 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PGHHMJKG_01360 1.81e-292 hisD 1.1.1.23 - E ko:K00013 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PGHHMJKG_01361 2.02e-138 hisB 4.2.1.19 - E ko:K01693 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 imidazoleglycerol-phosphate dehydratase
PGHHMJKG_01362 3.29e-146 hisH - - E ko:K02501 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PGHHMJKG_01363 4.61e-167 hisA 5.3.1.16 - E ko:K01814 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PGHHMJKG_01364 3.97e-176 hisF - - E ko:K02500 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PGHHMJKG_01365 2.93e-143 hisI 3.5.4.19, 3.6.1.31 - E ko:K01496,ko:K11755 ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 belongs to the PRA-CH family
PGHHMJKG_01366 3.7e-111 - - - - - - - -
PGHHMJKG_01367 0.0 - - - - - - - -
PGHHMJKG_01369 0.0 lmrA 3.6.3.44 - V ko:K02021,ko:K18104 ko01501,ko02010,map01501,map02010 ko00000,ko00001,ko00002,ko01000,ko01504,ko02000 ABC transporter
PGHHMJKG_01370 0.0 yvcD - - S - - - COG0457 FOG TPR repeat
PGHHMJKG_01371 1.08e-184 spl - - M ko:K21471 - ko00000,ko01000,ko01002,ko01011 protein conserved in bacteria
PGHHMJKG_01372 3.89e-220 trxB 1.8.1.9 - C ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PGHHMJKG_01373 9.76e-117 yvcI 3.6.1.55 - F ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGHHMJKG_01374 2.09e-213 yvcJ - - S ko:K06958 - ko00000,ko03019 Displays ATPase and GTPase activities
PGHHMJKG_01375 5.52e-226 yvcK - - S - - - Required for morphogenesis under gluconeogenic growth conditions
PGHHMJKG_01376 1.04e-219 whiA - - K ko:K09762 - ko00000 May be required for sporulation
PGHHMJKG_01377 3.92e-50 crh - - G ko:K11184 - ko00000 Phosphocarrier protein Chr
PGHHMJKG_01378 8.35e-185 yvcN 2.3.1.118 - Q ko:K00675 - ko00000,ko01000 Belongs to the arylamine N-acetyltransferase family
PGHHMJKG_01379 7.42e-29 - - - - - - - -
PGHHMJKG_01380 3.69e-169 yvcP - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_01381 1.68e-252 yvcQ - - T - - - His Kinase A (phosphoacceptor) domain
PGHHMJKG_01382 3.67e-180 yxdL_2 - - V ko:K02003,ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01383 0.0 - - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease)
PGHHMJKG_01384 5.45e-233 yvcT 1.1.1.215, 1.1.1.26, 1.1.1.79, 1.1.1.81 - CH ko:K00015,ko:K00090 ko00030,ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00030,map00260,map00620,map00630,map01100,map01110,map01120 ko00000,ko00001,ko01000 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHHMJKG_01385 5.3e-137 yvdA 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PGHHMJKG_01386 0.0 yvdB - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PGHHMJKG_01387 3.2e-70 yvdC - - S - - - MazG nucleotide pyrophosphohydrolase domain
PGHHMJKG_01388 3.11e-136 yvdD 3.2.2.10 - S ko:K06966 ko00230,ko00240,map00230,map00240 ko00000,ko00001,ko01000 Belongs to the LOG family
PGHHMJKG_01389 1.54e-221 yvdE - - K - - - Transcriptional regulator
PGHHMJKG_01390 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G ko:K01208 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Alpha amylase, N-terminal ig-like domain
PGHHMJKG_01391 3.44e-301 mdxE - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
PGHHMJKG_01392 2.88e-307 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
PGHHMJKG_01393 2.29e-188 malD - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
PGHHMJKG_01394 1.02e-199 malA - - S - - - Protein of unknown function (DUF1189)
PGHHMJKG_01395 0.0 yvdK 2.4.1.8 GH65 G ko:K00691 ko00500,ko01100,map00500,map01100 ko00000,ko00001,ko01000 Glycoside hydrolase, family 65
PGHHMJKG_01396 0.0 malL 3.2.1.10 GH13 G ko:K01182 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PGHHMJKG_01397 4.39e-146 pgmB 5.4.2.6 - S ko:K01838 ko00500,map00500 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PGHHMJKG_01398 8.17e-135 clpP 3.4.21.92 - OU ko:K01358 ko04112,ko04212,map04112,map04212 ko00000,ko00001,ko01000,ko01002 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PGHHMJKG_01400 4.53e-95 yvdQ - - S - - - Protein of unknown function (DUF3231)
PGHHMJKG_01401 4.21e-66 yvdR - - P ko:K11741 - ko00000,ko02000 Small Multidrug Resistance protein
PGHHMJKG_01402 2.57e-67 yvdS - - P ko:K18924 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PGHHMJKG_01403 4.76e-137 yvdT_1 - - K - - - Transcriptional regulator
PGHHMJKG_01404 0.0 ybeC - - E - - - amino acid
PGHHMJKG_01405 0.0 sacC3 3.2.1.65 GH32 G ko:K01212 ko00500,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 32 family
PGHHMJKG_01406 0.0 sacB 2.4.1.10, 2.4.1.9 GH68 M ko:K00692,ko:K20811 ko00500,ko01100,ko02020,map00500,map01100,map02020 ko00000,ko00001,ko01000,ko01003 levansucrase activity
PGHHMJKG_01407 3.77e-79 pbpE - - V - - - Beta-lactamase
PGHHMJKG_01408 2.17e-224 pbpE - - V - - - Beta-lactamase
PGHHMJKG_01409 8.23e-71 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PGHHMJKG_01410 6.31e-76 racX 5.1.1.13 - M ko:K01779 ko00250,ko01054,map00250,map01054 ko00000,ko00001,ko01000 Belongs to the aspartate glutamate racemases family
PGHHMJKG_01411 1.27e-22 - - - S - - - Protein of unknown function (DUF3237)
PGHHMJKG_01412 1.18e-60 - - - S - - - Protein of unknown function (DUF3237)
PGHHMJKG_01413 5.4e-120 padC - - Q ko:K13727 - ko00000,ko01000 Phenolic acid decarboxylase
PGHHMJKG_01415 0.0 pnbA - CE10 I ko:K03929 - ko00000,ko01000 Belongs to the type-B carboxylesterase lipase family
PGHHMJKG_01416 2.07e-97 - - - K ko:K19417 - ko00000,ko03000 transcriptional
PGHHMJKG_01417 2.78e-158 epsA - - M ko:K19420 - ko00000 biosynthesis protein
PGHHMJKG_01418 2.28e-149 ywqD 2.7.10.2 - D ko:K00903 - ko00000,ko01000,ko01001 COG0489 ATPases involved in chromosome partitioning
PGHHMJKG_01419 0.0 capD - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PGHHMJKG_01420 5.25e-280 epsD - GT4 M ko:K19422 - ko00000,ko01000 Glycosyl transferase 4-like
PGHHMJKG_01421 2.16e-202 epsE - GT2 M ko:K19423 - ko00000,ko01000,ko01003 COG0463 Glycosyltransferases involved in cell wall biogenesis
PGHHMJKG_01422 2.06e-277 epsF - GT4 M ko:K19424 - ko00000,ko01000,ko01003 Glycosyl transferases group 1
PGHHMJKG_01423 7.25e-264 epsG - - S ko:K19419 - ko00000,ko02000 EpsG family
PGHHMJKG_01424 9.61e-246 epsH - GT2 S ko:K19425 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PGHHMJKG_01425 1.83e-257 epsI - - GM ko:K19426 - ko00000,ko01000 pyruvyl transferase
PGHHMJKG_01426 5.49e-240 epsJ - GT2 S ko:K19427 - ko00000,ko01000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PGHHMJKG_01427 0.0 epsK - - S ko:K19418 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGHHMJKG_01428 3.19e-139 epsL - - M ko:K13012,ko:K19428 - ko00000,ko01000,ko01005 COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PGHHMJKG_01429 3.33e-76 epsM - - GM ko:K19429 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PGHHMJKG_01430 1.06e-278 epsN - - E ko:K19430 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PGHHMJKG_01431 3.07e-240 epsO - - GM ko:K19431 - ko00000,ko01000 Exopolysaccharide biosynthesis protein
PGHHMJKG_01432 5.69e-44 yvfG - - S - - - YvfG protein
PGHHMJKG_01433 4.16e-118 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PGHHMJKG_01434 7.32e-143 rpoN - - K ko:K03092 ko02020,ko05111,map02020,map05111 ko00000,ko00001,ko03021 COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PGHHMJKG_01435 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PGHHMJKG_01436 5.87e-147 yvfI - - K ko:K05799 - ko00000,ko03000 COG2186 Transcriptional regulators
PGHHMJKG_01437 6.96e-237 lacR - - K ko:K02529 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01438 3.8e-291 cycB - - G ko:K02027,ko:K15770,ko:K17237 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2182 Maltose-binding periplasmic proteins domains
PGHHMJKG_01439 5.29e-301 malC - - P ko:K15771 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1175 ABC-type sugar transport systems, permease components
PGHHMJKG_01440 3.82e-194 malG - - P ko:K15772 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport
PGHHMJKG_01441 0.0 lacA 3.2.1.23 - G ko:K12308 ko00052,map00052 ko00000,ko00001,ko01000 beta-galactosidase
PGHHMJKG_01442 0.0 ganB 3.2.1.89 - G ko:K01224 - ko00000,ko01000 arabinogalactan
PGHHMJKG_01443 1.89e-259 - 3.1.3.3 - T ko:K07315 - ko00000,ko01000,ko03021 response regulator
PGHHMJKG_01444 8.47e-200 rsbQ - - S ko:K19707 - ko00000,ko03021 Alpha/beta hydrolase family
PGHHMJKG_01445 1.1e-204 yvfR - - V ko:K01990 - ko00000,ko00002,ko02000 COG1131 ABC-type multidrug transport system, ATPase component
PGHHMJKG_01446 8.31e-170 XK27_09830 - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PGHHMJKG_01447 6.28e-251 yvfT 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_01448 4.36e-136 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_01449 4.23e-42 - - - K - - - Transcriptional regulator PadR-like family
PGHHMJKG_01450 3.88e-57 - - - S - - - Protein of unknown function (DUF2812)
PGHHMJKG_01451 7.47e-174 lutA - - C ko:K18928 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PGHHMJKG_01452 0.0 lutB - - C ko:K18929 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PGHHMJKG_01453 6.88e-171 lutC - - S ko:K00782 - ko00000 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PGHHMJKG_01454 2.7e-187 - - - S - - - Glycosyl hydrolase
PGHHMJKG_01455 7.07e-307 yvbW - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_01456 5.59e-198 yvbV - - EG - - - EamA-like transporter family
PGHHMJKG_01457 1.99e-205 yvbU - - K - - - Transcriptional regulator
PGHHMJKG_01458 6.01e-245 yvbT - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGHHMJKG_01459 1.51e-258 araR - - K ko:K02103 - ko00000,ko03000 transcriptional
PGHHMJKG_01460 0.0 araE - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGHHMJKG_01461 4.01e-236 cggR - - K ko:K05311 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PGHHMJKG_01462 5.72e-238 gapA 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGHHMJKG_01463 1.97e-277 pgk 2.7.2.3 - F ko:K00927 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the phosphoglycerate kinase family
PGHHMJKG_01464 2.12e-176 tpiA 5.3.1.1 - G ko:K01803 ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PGHHMJKG_01465 0.0 gpmI 5.4.2.12 - G ko:K15633 ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of 2-phosphoglycerate and
PGHHMJKG_01466 1.38e-309 eno 4.2.1.11 - G ko:K01689 ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066 ko00000,ko00001,ko00002,ko01000,ko03019,ko04147 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PGHHMJKG_01467 9.77e-106 yvbK - - K - - - acetyltransferase
PGHHMJKG_01468 0.0 tcaA - - S ko:K21463 - ko00000 response to antibiotic
PGHHMJKG_01469 2.66e-155 yvbI - - M - - - Membrane
PGHHMJKG_01470 1.2e-144 yvbH - - S - - - YvbH-like oligomerisation region
PGHHMJKG_01471 1.32e-133 yvbG - - U ko:K05595 - ko00000,ko02000 UPF0056 membrane protein
PGHHMJKG_01472 8.29e-129 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PGHHMJKG_01473 3.23e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PGHHMJKG_01474 4.63e-144 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PGHHMJKG_01475 1.23e-221 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PGHHMJKG_01476 1.13e-135 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PGHHMJKG_01477 3.28e-122 yvbF - - K ko:K22301 - ko00000,ko03000 Belongs to the GbsR family
PGHHMJKG_01478 2.46e-269 opuCA - - E ko:K05847 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PGHHMJKG_01479 1.27e-141 opuCB - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PGHHMJKG_01480 7.93e-219 opuCC - - M ko:K05845 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PGHHMJKG_01481 3.07e-142 opuCD - - P ko:K05846 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1174 ABC-type proline glycine betaine transport systems, permease component
PGHHMJKG_01483 0.0 argS 6.1.1.19 - J ko:K01887 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Arginyl-tRNA synthetase
PGHHMJKG_01484 5.42e-95 ywiB - - S - - - protein conserved in bacteria
PGHHMJKG_01485 3.71e-12 - - - S - - - Bacteriocin subtilosin A
PGHHMJKG_01486 0.0 - - - C ko:K22227 - ko00000 Fe-S oxidoreductases
PGHHMJKG_01488 5.02e-168 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter
PGHHMJKG_01489 1.81e-292 mgtA 3.6.3.2 - P ko:K01531,ko:K16905 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPase, P-type transporting, HAD superfamily, subfamily IC
PGHHMJKG_01490 3.84e-273 - 2.7.1.26, 2.7.7.2 - L ko:K07263,ko:K11753 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01002 Peptidase, M16
PGHHMJKG_01491 1.17e-315 - - - L - - - Peptidase, M16
PGHHMJKG_01493 1.31e-303 ywhL - - CO - - - amine dehydrogenase activity
PGHHMJKG_01494 1.57e-96 ywhK - - CO - - - amine dehydrogenase activity
PGHHMJKG_01495 1.72e-156 ywhK - - CO - - - amine dehydrogenase activity
PGHHMJKG_01496 3.28e-99 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PGHHMJKG_01498 2.76e-65 - - - S - - - Aminoacyl-tRNA editing domain
PGHHMJKG_01499 2.1e-215 speB 3.5.3.11 - E ko:K01480 ko00330,ko01100,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the arginase family
PGHHMJKG_01500 1.93e-204 speE 2.5.1.16 - E ko:K00797 ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PGHHMJKG_01501 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M ko:K21464 ko00550,map00550 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PGHHMJKG_01502 2.1e-64 - - - - - - - -
PGHHMJKG_01503 1.92e-123 ywhD - - S - - - YwhD family
PGHHMJKG_01504 3.29e-154 ywhC - - S - - - Peptidase family M50
PGHHMJKG_01505 1.43e-35 dmpI 5.3.2.6 - G ko:K01821 ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00362,map00621,map00622,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 4-oxalocrotonate tautomerase
PGHHMJKG_01506 1.45e-93 ywhA - - K - - - Transcriptional regulator
PGHHMJKG_01507 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGHHMJKG_01509 1.54e-306 mmr - - U ko:K08166 - ko00000,ko02000 Major Facilitator Superfamily
PGHHMJKG_01510 1.1e-103 yffB - - K - - - Transcriptional regulator
PGHHMJKG_01511 1.47e-115 ywgA - - - ko:K09388 - ko00000 -
PGHHMJKG_01512 0.0 ywfO - - S ko:K06885 - ko00000 COG1078 HD superfamily phosphohydrolases
PGHHMJKG_01513 8.55e-49 ywzC - - S - - - Belongs to the UPF0741 family
PGHHMJKG_01514 6.58e-146 rsfA_1 - - - ko:K06314 - ko00000,ko03000 -
PGHHMJKG_01515 5.88e-200 ywfM - - EG ko:K03298 - ko00000,ko02000 EamA-like transporter family
PGHHMJKG_01516 4.16e-197 lipL 2.3.1.200, 2.3.1.204 - H ko:K16869,ko:K18821 - ko00000,ko01000 Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PGHHMJKG_01517 3.73e-209 cysL - - K ko:K21900 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01518 1.67e-224 pta 2.3.1.8, 3.6.3.21 - C ko:K00625,ko:K02028 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000,ko02000 In Salmonella this enzyme is required for ethanolamine catabolism
PGHHMJKG_01519 1.4e-186 ywfI - - C ko:K00435 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko01000 May function as heme-dependent peroxidase
PGHHMJKG_01520 1.95e-175 ywfH - - IQ ko:K19550 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Enoyl-(Acyl carrier protein) reductase
PGHHMJKG_01521 3.03e-294 ywfG - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase class I and II
PGHHMJKG_01522 3.21e-267 bacE - - EGP ko:K19552 - ko00000,ko02000 Part of the bacilysin biosynthesis operon. May be involved in self-resistance to bacilysin by permitting efflux of this antibiotic
PGHHMJKG_01523 0.0 bacD 6.3.2.49 - F ko:K13037 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PGHHMJKG_01524 1.33e-179 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_01525 1.24e-175 bacB 5.3.3.19 - S ko:K19547 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PGHHMJKG_01526 5.11e-146 bacA 4.1.1.100 - E ko:K19546 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PGHHMJKG_01527 3.36e-181 ysnF - - S - - - protein conserved in bacteria
PGHHMJKG_01528 3.28e-46 ysnE - - K ko:K03829 - ko00000,ko01000 acetyltransferase
PGHHMJKG_01530 0.0 ilvB 2.2.1.6 - E ko:K01652,ko:K16787 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PGHHMJKG_01531 5.05e-110 ilvN 2.2.1.6 - E ko:K01653,ko:K16785 ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Acetolactate synthase
PGHHMJKG_01532 9.59e-245 ilvC 1.1.1.86 - EH ko:K00053 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PGHHMJKG_01533 0.0 leuA 2.3.3.13 - E ko:K01649 ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PGHHMJKG_01534 2.04e-253 leuB 1.1.1.85 - CE ko:K00052 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PGHHMJKG_01535 0.0 leuC 4.2.1.33, 4.2.1.35 - E ko:K01703 ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGHHMJKG_01536 4.4e-149 leuD 4.2.1.33, 4.2.1.35 - E ko:K01704 ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PGHHMJKG_01537 2.62e-238 ysoA - - H - - - Tetratricopeptide repeat
PGHHMJKG_01538 5.98e-285 tig - - D ko:K03545 - ko00000 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PGHHMJKG_01539 1.15e-296 clpX - - O ko:K03544 ko04112,map04112 ko00000,ko00001,ko03110 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PGHHMJKG_01540 0.0 lonB 3.4.21.53 - LO ko:K04076 - ko00000,ko01000,ko01002 Belongs to the peptidase S16 family
PGHHMJKG_01541 0.0 lon 3.4.21.53 - O ko:K01338 ko04112,map04112 ko00000,ko00001,ko01000,ko01002 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PGHHMJKG_01542 7.6e-139 engB - - D ko:K03978 - ko00000,ko03036 Necessary for normal cell division and for the maintenance of normal septation
PGHHMJKG_01543 4.77e-116 ysxD - - - - - - -
PGHHMJKG_01544 6.39e-316 hemA 1.2.1.70 - H ko:K02492 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PGHHMJKG_01545 6.56e-187 hemX - - O ko:K02497 - ko00000 cytochrome C
PGHHMJKG_01546 6.27e-220 hemC 2.5.1.61 - H ko:K01749 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PGHHMJKG_01547 4.13e-183 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PGHHMJKG_01548 2.14e-232 hemB 4.2.1.24 - H ko:K01698 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the ALAD family
PGHHMJKG_01549 1.44e-311 hemL 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PGHHMJKG_01550 0.0 spoVID - - M ko:K06417 - ko00000 stage VI sporulation protein D
PGHHMJKG_01551 2.39e-252 ysxE - - S - - - A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PGHHMJKG_01552 1.53e-35 - - - - - - - -
PGHHMJKG_01553 0.0 valS 6.1.1.9 - J ko:K01873 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PGHHMJKG_01554 6.38e-315 folC 6.3.2.12, 6.3.2.17 - H ko:K11754 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the folylpolyglutamate synthase family
PGHHMJKG_01555 1.28e-108 comC 3.4.23.43 - NOU ko:K02236,ko:K02654 - ko00000,ko00002,ko01000,ko01002,ko02035,ko02044 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PGHHMJKG_01556 1.43e-209 spoIIB - - S ko:K06380 - ko00000 Sporulation related domain
PGHHMJKG_01557 2.02e-131 maf - - D ko:K06287 - ko00000 septum formation protein Maf
PGHHMJKG_01558 2.4e-162 radC - - E ko:K03630 - ko00000 Belongs to the UPF0758 family
PGHHMJKG_01559 5.26e-235 mreB - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod shape-determining protein MreB
PGHHMJKG_01560 7.78e-202 mreC - - M ko:K03570 - ko00000,ko03036 Involved in formation and maintenance of cell shape
PGHHMJKG_01561 8.72e-111 mreD - - M ko:K03571 - ko00000,ko03036 shape-determining protein
PGHHMJKG_01562 4.3e-158 minC - - D ko:K03610 - ko00000,ko03036,ko04812 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PGHHMJKG_01563 4.13e-186 minD - - D ko:K03609 - ko00000,ko03036,ko04812 Belongs to the ParA family
PGHHMJKG_01564 7.44e-187 spoIVFA - - M ko:K06401 - ko00000 COG0739 Membrane proteins related to metalloendopeptidases
PGHHMJKG_01565 1.52e-207 spoIVFB - - S ko:K06402 - ko00000,ko01000,ko01002 Stage IV sporulation protein
PGHHMJKG_01566 6.34e-66 rplU - - J ko:K02888 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 This protein binds to 23S rRNA in the presence of protein L20
PGHHMJKG_01567 2.66e-74 ysxB - - J ko:K07584 - ko00000 ribosomal protein
PGHHMJKG_01568 2.7e-61 rpmA - - J ko:K02899 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL27 family
PGHHMJKG_01569 4.25e-139 spo0B - - T ko:K06375 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko01000 Sporulation initiation phospho-transferase B, C-terminal
PGHHMJKG_01570 9.66e-309 obg - - S ko:K03979 - ko00000,ko01000,ko03009 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PGHHMJKG_01571 4.75e-96 pheB 5.4.99.5 - S ko:K06209 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the UPF0735 family
PGHHMJKG_01572 2.54e-209 pheA 4.2.1.51 - E ko:K04518 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Prephenate dehydratase
PGHHMJKG_01573 5.02e-123 yrxA - - S ko:K07105 - ko00000 small molecule binding protein (contains 3H domain)
PGHHMJKG_01574 1.17e-290 nifS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PGHHMJKG_01575 0.0 nadB 1.4.3.16 - H ko:K00278 ko00250,ko00760,ko01100,map00250,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of L-aspartate to iminoaspartate
PGHHMJKG_01576 1.02e-201 nadC 2.4.2.19 - H ko:K00767 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NadC ModD family
PGHHMJKG_01577 4.41e-270 nadA 2.5.1.72 - H ko:K03517 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PGHHMJKG_01578 3.45e-217 safA - - M ko:K06370 - ko00000 spore coat assembly protein SafA
PGHHMJKG_01579 5.13e-70 - - - S ko:K06345 - ko00000 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PGHHMJKG_01580 3.51e-164 yebC - - K - - - transcriptional regulatory protein
PGHHMJKG_01581 0.0 yrbD - - E ko:K03310 - ko00000 Sodium alanine symporter
PGHHMJKG_01583 2.55e-67 - - - S - - - Family of unknown function (DUF5412)
PGHHMJKG_01585 1.91e-151 yrzF - - T - - - serine threonine protein kinase
PGHHMJKG_01586 1.67e-247 idhA 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, NAD-binding Rossmann fold
PGHHMJKG_01587 0.0 csbX - - EGP - - - the major facilitator superfamily
PGHHMJKG_01588 6.46e-121 bofC - - S ko:K06318 - ko00000 BofC C-terminal domain
PGHHMJKG_01589 2.84e-137 ruvA 3.6.4.12 - L ko:K03550 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PGHHMJKG_01590 9.14e-239 ruvB 3.6.4.12 - L ko:K03551 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PGHHMJKG_01591 2.91e-30 yrzS - - S - - - Protein of unknown function (DUF2905)
PGHHMJKG_01592 6.03e-248 queA 2.4.99.17 - J ko:K07568 - ko00000,ko01000,ko03016 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PGHHMJKG_01593 4.74e-292 tgt 2.4.2.29 - F ko:K00773 - ko00000,ko01000,ko03016 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PGHHMJKG_01594 1.29e-52 yajC - - U ko:K03210 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit YajC
PGHHMJKG_01595 2.16e-98 yrzE - - S - - - Protein of unknown function (DUF3792)
PGHHMJKG_01596 8.64e-145 yrbG - - S - - - membrane
PGHHMJKG_01597 0.0 spoVB - - S ko:K06409 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGHHMJKG_01598 1.93e-65 yrzD - - S - - - Post-transcriptional regulator
PGHHMJKG_01599 0.0 secD - - U ko:K03072,ko:K12257 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PGHHMJKG_01600 5.35e-113 trkA1 - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PGHHMJKG_01601 1.07e-64 yrvD - - S - - - Lipopolysaccharide assembly protein A domain
PGHHMJKG_01602 0.0 recJ - - L ko:K07462 ko03410,ko03430,ko03440,map03410,map03430,map03440 ko00000,ko00001,ko01000,ko03400 Single-stranded-DNA-specific exonuclease RecJ
PGHHMJKG_01603 2.53e-118 apt 2.4.2.7 - F ko:K00759 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000,ko04147 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PGHHMJKG_01604 0.0 relA 2.7.6.5 - KT ko:K00951 ko00230,map00230 ko00000,ko00001,ko01000 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PGHHMJKG_01605 1.36e-90 dtd - - J ko:K07560 - ko00000,ko01000,ko03016 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PGHHMJKG_01606 0.0 lytH 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 COG3103 SH3 domain protein
PGHHMJKG_01608 3e-310 hisS 6.1.1.21 - J ko:K01892 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 histidyl-tRNA synthetase
PGHHMJKG_01609 0.0 aspS 6.1.1.12 - J ko:K01876 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PGHHMJKG_01610 2.29e-176 yrvM - - H ko:K22132 - ko00000,ko03016 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PGHHMJKG_01611 6.69e-301 rarA - - L ko:K07478 - ko00000 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PGHHMJKG_01612 8.12e-93 cymR - - K ko:K17472 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01613 2.56e-270 iscS 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Cysteine desulfurase
PGHHMJKG_01614 5.64e-279 mnmA 2.8.1.13 - J ko:K00566 ko04122,map04122 ko00000,ko00001,ko01000,ko03016 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PGHHMJKG_01615 1.01e-20 yrrB - - S - - - COG0457 FOG TPR repeat
PGHHMJKG_01616 0.0 recD2 3.1.11.5 - L ko:K03581 ko03440,map03440 ko00000,ko00001,ko01000,ko03400 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PGHHMJKG_01617 2.79e-105 yrrD - - S - - - protein conserved in bacteria
PGHHMJKG_01618 8.4e-42 yrzR - - - - - - -
PGHHMJKG_01619 8.96e-11 - - - S - - - Protein of unknown function (DUF3918)
PGHHMJKG_01620 3.96e-191 spo0J - - K ko:K03497 - ko00000,ko03000,ko03036,ko04812 Belongs to the ParB family
PGHHMJKG_01621 4.79e-173 soj - - D ko:K03496 - ko00000,ko03036,ko04812 COG1192 ATPases involved in chromosome partitioning
PGHHMJKG_01622 3.77e-97 - - - S - - - Bacterial PH domain
PGHHMJKG_01623 9e-193 noc - - D ko:K03497 - ko00000,ko03000,ko03036,ko04812 Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PGHHMJKG_01624 8.33e-167 rsmG 2.1.1.170 - J ko:K03501 - ko00000,ko01000,ko03009,ko03036 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PGHHMJKG_01625 0.0 gidA - - D ko:K03495 - ko00000,ko03016,ko03036 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PGHHMJKG_01626 0.0 mnmE - - S ko:K03650 - ko00000,ko01000,ko03016 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PGHHMJKG_01627 4.32e-140 jag - - S ko:K06346 - ko00000 single-stranded nucleic acid binding R3H
PGHHMJKG_01628 9.29e-179 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGHHMJKG_01629 1.64e-70 rnpA 3.1.26.5 - J ko:K03536 - ko00000,ko01000,ko03016 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PGHHMJKG_01630 0.0 dnaA - - L ko:K02313 ko02020,ko04112,map02020,map04112 ko00000,ko00001,ko03032,ko03036 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PGHHMJKG_01631 9.88e-263 dnaN 2.7.7.7 - L ko:K02338 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PGHHMJKG_01632 2.24e-45 yaaA - - S ko:K14761 - ko00000,ko03009 S4 domain
PGHHMJKG_01633 1.85e-263 recF - - L ko:K03629 ko03440,map03440 ko00000,ko00001,ko03400 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PGHHMJKG_01634 1.25e-51 yaaB - - S - - - Domain of unknown function (DUF370)
PGHHMJKG_01635 0.0 gyrB 5.99.1.3 - L ko:K02470 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGHHMJKG_01636 0.0 gyrA 5.99.1.3 - L ko:K02469 - ko00000,ko01000,ko03032,ko03400 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PGHHMJKG_01637 1.27e-55 ytzC - - S - - - Protein of unknown function (DUF2524)
PGHHMJKG_01638 4.06e-245 ytqA - - S ko:K07139 - ko00000 Fe-S oxidoreductase
PGHHMJKG_01639 2.75e-136 ytqB - - J - - - Putative rRNA methylase
PGHHMJKG_01640 2.78e-275 ytpB 4.2.3.130 - S ko:K16188 - ko00000,ko01000 Tetraprenyl-beta-curcumene synthase
PGHHMJKG_01641 2.33e-192 ytpA 3.1.1.5 - I ko:K01048 ko00564,map00564 ko00000,ko00001,ko01000 Alpha beta hydrolase
PGHHMJKG_01642 5.88e-88 ytoA - - S - - - COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PGHHMJKG_01643 0.0 ytnA - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_01644 0.0 asnB 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PGHHMJKG_01645 2.26e-286 metK 2.5.1.6 - H ko:K00789 ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PGHHMJKG_01646 0.0 pckA 4.1.1.49 - C ko:K01610 ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PGHHMJKG_01647 5.75e-52 ytmB - - S - - - Protein of unknown function (DUF2584)
PGHHMJKG_01648 9.48e-191 ytmA - - E - - - COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PGHHMJKG_01649 7.95e-242 ytlA - - P ko:K02051 - ko00000,ko00002,ko02000 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PGHHMJKG_01650 1.5e-184 ytlC 3.6.3.36 - P ko:K02049,ko:K10831,ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PGHHMJKG_01651 1.09e-182 ytlD - - P ko:K02050 - ko00000,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PGHHMJKG_01652 4.47e-113 ytkD 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PGHHMJKG_01653 1.52e-79 ytkC - - S - - - Bacteriophage holin family
PGHHMJKG_01654 1.8e-99 dps - - P ko:K04047 - ko00000,ko03036 Belongs to the Dps family
PGHHMJKG_01656 4.78e-95 ytkA - - S - - - YtkA-like
PGHHMJKG_01657 8.36e-113 luxS 4.4.1.21 - T ko:K07173 ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111 ko00000,ko00001,ko00002,ko01000 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PGHHMJKG_01658 8.96e-134 ytiB 4.2.1.1 - P ko:K01673 ko00910,map00910 ko00000,ko00001,ko01000 Reversible hydration of carbon dioxide
PGHHMJKG_01659 5.02e-56 rpmE2 - - J ko:K02909 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein L31
PGHHMJKG_01660 1.03e-315 ythA 1.10.3.14 - C ko:K00425 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 oxidase, subunit
PGHHMJKG_01661 1.64e-238 ythB 1.10.3.14 - C ko:K00426 ko00190,ko01100,ko02020,map00190,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PGHHMJKG_01662 2.43e-34 - - - S - - - Domain of Unknown Function (DUF1540)
PGHHMJKG_01663 7.92e-193 mntD - - P ko:K11709,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
PGHHMJKG_01664 5.85e-293 mntC - - P ko:K11705,ko:K11708,ko:K19976 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PGHHMJKG_01665 1.5e-179 mntB 3.6.3.35 - P ko:K02074,ko:K09820,ko:K11710,ko:K19973 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PGHHMJKG_01666 3.23e-218 troA - - P ko:K11707 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PGHHMJKG_01667 1.43e-272 menC 4.2.1.113 - H ko:K02549 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PGHHMJKG_01668 0.0 menE 6.2.1.26 - H ko:K01911 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PGHHMJKG_01669 3.45e-200 menB 4.1.3.36 - H ko:K01661 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PGHHMJKG_01670 9.85e-197 menH 4.2.99.20 - S ko:K08680 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PGHHMJKG_01671 0.0 menD 2.2.1.9 - H ko:K02551 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PGHHMJKG_01672 0.0 menF 5.4.4.2 - HQ ko:K02552 ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Isochorismate synthase
PGHHMJKG_01673 1.44e-167 yteA - - T - - - COG1734 DnaK suppressor protein
PGHHMJKG_01674 5.69e-195 ytdA 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Nucleotidyl transferase
PGHHMJKG_01675 4.1e-310 ytcA 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PGHHMJKG_01676 2.78e-224 ytcB - - M - - - NAD-dependent epimerase dehydratase
PGHHMJKG_01677 7.32e-292 - - - M ko:K06338 - ko00000 Glycosyltransferase Family 4
PGHHMJKG_01679 6.65e-261 cotS - - S ko:K06337 - ko00000 Seems to be required for the assembly of the CotSA protein in spores
PGHHMJKG_01680 1.61e-272 cotSA - - M ko:K06338 - ko00000 Glycosyl transferases group 1
PGHHMJKG_01681 3.68e-260 cotI - - S ko:K06331 - ko00000 Spore coat protein
PGHHMJKG_01682 1.75e-95 ytaB - - T ko:K05770 ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166 ko00000,ko00001,ko02000 membrane
PGHHMJKG_01683 0.0 glgP 2.4.1.1 GT35 G ko:K00688 ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931 ko00000,ko00001,ko01000 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PGHHMJKG_01684 0.0 glgA 2.4.1.21 GT5 G ko:K00703 ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000,ko01003 Synthesizes alpha-1,4-glucan chains using ADP-glucose
PGHHMJKG_01685 1.58e-239 glgD 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Glucose-1-phosphate adenylyltransferase, GlgD subunit
PGHHMJKG_01686 8.49e-265 glgC 2.7.7.27 - G ko:K00975 ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PGHHMJKG_01687 0.0 glgB 2.4.1.18 CBM48,GH13 G ko:K00700 ko00500,ko01100,ko01110,map00500,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PGHHMJKG_01709 3.97e-119 yozB - - S ko:K08976 - ko00000 membrane
PGHHMJKG_01710 8.69e-184 - - - - - - - -
PGHHMJKG_01711 7.04e-118 yocC - - - - - - -
PGHHMJKG_01712 1.41e-242 yocD 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 peptidase S66
PGHHMJKG_01713 3.99e-258 des 1.14.19.23, 1.14.19.45 - I ko:K10255 ko02020,map02020 ko00000,ko00001,ko01000,ko01004 fatty acid desaturase
PGHHMJKG_01714 4.09e-251 desK 2.7.13.3 - T ko:K07778 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_01715 4.71e-135 desR - - T ko:K02479,ko:K07693 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_01717 6.78e-174 yocH - - M - - - COG1388 FOG LysM repeat
PGHHMJKG_01718 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PGHHMJKG_01719 1.46e-147 azoR - - I ko:K01118 - ko00000,ko01000 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PGHHMJKG_01720 2.87e-107 yocK - - T - - - general stress protein
PGHHMJKG_01721 2.81e-55 yocL - - - - - - -
PGHHMJKG_01722 3.93e-41 - - - - - - - -
PGHHMJKG_01723 5.43e-114 yocM - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PGHHMJKG_01724 2.94e-55 yozN - - - - - - -
PGHHMJKG_01725 1.83e-49 yocN - - - - - - -
PGHHMJKG_01726 2.17e-74 yozO - - S - - - Bacterial PH domain
PGHHMJKG_01727 1.91e-42 yozC - - - - - - -
PGHHMJKG_01728 0.0 dhaS 1.2.1.3, 1.2.1.39 - C ko:K00128,ko:K00146 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PGHHMJKG_01729 4.02e-203 glxR 1.1.1.31 - I ko:K00020 ko00280,ko01100,map00280,map01100 ko00000,ko00001,ko01000 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PGHHMJKG_01730 0.0 mcpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_01731 6.21e-162 ykwB - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_01732 5.86e-255 splB 4.1.99.14 - L ko:K03716 - ko00000,ko01000 Spore photoproduct lyase
PGHHMJKG_01733 1.54e-51 splA - - S ko:K06315 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01734 0.0 ptsI 2.7.3.9 - G ko:K08483 ko02060,map02060 ko00000,ko00001,ko01000,ko02000 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PGHHMJKG_01735 1.51e-53 ptsH - - G ko:K11189 - ko00000,ko02000 phosphocarrier protein HPr
PGHHMJKG_01736 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_01737 1.97e-167 glcT - - K ko:K03480,ko:K03488 - ko00000,ko03000 antiterminator
PGHHMJKG_01738 2.21e-228 ykvZ - - K - - - Transcriptional regulator
PGHHMJKG_01739 3.19e-263 ykvY 3.4.13.9 - E ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PGHHMJKG_01740 3.99e-09 - - - - - - - -
PGHHMJKG_01741 0.0 zosA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PGHHMJKG_01742 1.12e-114 stoA - - CO - - - thiol-disulfide
PGHHMJKG_01743 6.46e-302 ykvU - - S - - - COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGHHMJKG_01744 1.83e-141 ykvT 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell Wall Hydrolase
PGHHMJKG_01745 2.6e-39 - - - - - - - -
PGHHMJKG_01746 5.43e-35 ykvS - - S - - - protein conserved in bacteria
PGHHMJKG_01747 8.95e-61 ykvR - - S - - - Protein of unknown function (DUF3219)
PGHHMJKG_01748 2.36e-125 queF 1.7.1.13 - S ko:K09457 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PGHHMJKG_01749 2.41e-177 queE 4.3.99.3 - H ko:K10026 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PGHHMJKG_01750 6.96e-105 queD 4.1.2.50, 4.2.3.12 - H ko:K01737 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000,ko03016 synthase
PGHHMJKG_01751 2.61e-160 queC 6.3.4.20 - F ko:K06920 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000,ko03016 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PGHHMJKG_01752 8.23e-228 ykvI - - S - - - membrane
PGHHMJKG_01753 0.0 clpE - - O ko:K03697,ko:K04086 - ko00000,ko03110 Belongs to the ClpA ClpB family
PGHHMJKG_01754 9.19e-177 motA - - N ko:K02556 ko02020,ko02030,ko02040,map02020,map02030,map02040 ko00000,ko00001,ko02000,ko02035 flagellar motor
PGHHMJKG_01755 1.51e-166 motB - - N ko:K02557 ko02030,ko02040,map02030,map02040 ko00000,ko00001,ko02000,ko02035 Flagellar motor protein
PGHHMJKG_01756 5.17e-99 ykvE - - K ko:K15973 - ko00000,ko03000 transcriptional
PGHHMJKG_01757 0.0 kinD 2.7.13.3 - T ko:K13532 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PGHHMJKG_01758 5.87e-74 eag - - - - - - -
PGHHMJKG_01760 8.82e-68 - - - S - - - Protein of unknown function (DUF1232)
PGHHMJKG_01761 1.02e-121 mtnD 1.13.11.53, 1.13.11.54 - S ko:K08967 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PGHHMJKG_01762 1.24e-144 mtnB 4.2.1.109 - E ko:K08964 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PGHHMJKG_01763 7.2e-175 mtnX 3.1.3.87 - E ko:K08966 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PGHHMJKG_01764 2.79e-294 mtnW 5.3.2.5 - G ko:K08965 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PGHHMJKG_01765 6.84e-296 mtnE - - E ko:K08969,ko:K19549 ko00270,ko01100,ko01130,map00270,map01100,map01130 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PGHHMJKG_01766 3.86e-191 mtnU 3.5.1.3 - S ko:K13566 ko00250,map00250 ko00000,ko00001,ko01000 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PGHHMJKG_01767 7.07e-293 mtnK 2.7.1.100 - F ko:K00899 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PGHHMJKG_01768 3.8e-252 mtnA 5.3.1.23 - E ko:K08963 ko00270,ko01100,map00270,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PGHHMJKG_01770 2.76e-115 ogt 2.1.1.63 - L ko:K00567,ko:K13531 - ko00000,ko01000,ko03400 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PGHHMJKG_01771 0.0 kinE 2.7.13.3 - T ko:K13533 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_01772 4.75e-244 ykrP - - G - - - COG3594 Fucose 4-O-acetylase and related acetyltransferases
PGHHMJKG_01773 4.83e-30 ykzE - - - - - - -
PGHHMJKG_01775 1.82e-310 ktrD - - P - - - COG0168 Trk-type K transport systems, membrane components
PGHHMJKG_01776 3.97e-199 htpX - - O ko:K03799 - ko00000,ko00002,ko01000,ko01002 Belongs to the peptidase M48B family
PGHHMJKG_01777 7.68e-160 ykrK - - S - - - Domain of unknown function (DUF1836)
PGHHMJKG_01778 1.4e-36 sspD - - S ko:K06421 - ko00000 small acid-soluble spore protein
PGHHMJKG_01779 3.83e-204 rsgI - - S - - - Anti-sigma factor N-terminus
PGHHMJKG_01780 1.8e-167 sigI - - K ko:K03093 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_01781 1.33e-226 ykoY - - P - - - COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PGHHMJKG_01782 1.71e-143 ykoX - - S - - - membrane-associated protein
PGHHMJKG_01783 0.0 ykoW 2.7.7.65 - T ko:K21023 ko02025,map02025 ko00000,ko00001,ko01000 Diguanylate cyclase
PGHHMJKG_01784 7.24e-204 ku - - L ko:K10979 ko03450,map03450 ko00000,ko00001,ko03400 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PGHHMJKG_01785 0.0 ligD 6.5.1.1 - L ko:K01971 ko03450,map03450 ko00000,ko00001,ko01000,ko03400 ATP-dependent DNA ligase
PGHHMJKG_01786 9.49e-238 ykoT - - M - - - COG0463 Glycosyltransferases involved in cell wall biogenesis
PGHHMJKG_01787 0.0 ykoS - - - - - - -
PGHHMJKG_01788 1.2e-195 ykoQ - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PGHHMJKG_01789 2.57e-122 ykoP - - G - - - polysaccharide deacetylase
PGHHMJKG_01790 6.33e-277 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
PGHHMJKG_01791 9.83e-106 ykoM - - K ko:K15973 - ko00000,ko03000 transcriptional
PGHHMJKG_01792 3.04e-36 ykoL - - - - - - -
PGHHMJKG_01793 1.63e-25 - - - - - - - -
PGHHMJKG_01794 1.49e-70 tnrA - - K - - - transcriptional
PGHHMJKG_01795 9.86e-300 mgtE - - P ko:K06213 - ko00000,ko02000 Acts as a magnesium transporter
PGHHMJKG_01797 1.45e-08 - - - - - - - -
PGHHMJKG_01798 1.3e-111 ykoJ - - S - - - Peptidase propeptide and YPEB domain
PGHHMJKG_01799 7.88e-145 ykoI - - S - - - Peptidase propeptide and YPEB domain
PGHHMJKG_01800 6.05e-307 ykoH - - T - - - Histidine kinase
PGHHMJKG_01801 1.68e-156 ykoG - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_01802 4.05e-141 ykoF - - S - - - YKOF-related Family
PGHHMJKG_01803 3.99e-127 ykoE - - S ko:K16925 - ko00000,ko00002,ko02000 ABC-type cobalt transport system, permease component
PGHHMJKG_01804 0.0 ykoD - - P ko:K16786,ko:K16787 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01805 5.18e-173 ykoC - - P ko:K16785 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Cobalt transport protein
PGHHMJKG_01806 3.99e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PGHHMJKG_01807 6.07e-225 isp - - O ko:K13275 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PGHHMJKG_01808 0.0 metE 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PGHHMJKG_01809 5.67e-115 guaD 3.5.4.3 - FJ ko:K01487 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 COG0590 Cytosine adenosine deaminases
PGHHMJKG_01810 4.72e-93 ohrB - - O - - - Organic hydroperoxide resistance protein
PGHHMJKG_01811 1.66e-96 ohrR - - K - - - COG1846 Transcriptional regulators
PGHHMJKG_01812 2.39e-93 ohrA - - O - - - Organic hydroperoxide resistance protein
PGHHMJKG_01813 4.59e-289 proA 1.2.1.41 - E ko:K00147 ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PGHHMJKG_01814 3.68e-256 proB 2.7.2.11 - E ko:K00931 ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PGHHMJKG_01815 1.66e-217 purU 3.5.1.10 - F ko:K01433 ko00630,ko00670,map00630,map00670 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PGHHMJKG_01816 1.94e-66 ykkD - - P ko:K18925 - ko00000,ko00002,ko02000 Multidrug resistance protein
PGHHMJKG_01817 2.99e-71 ykkC - - P ko:K18924 - ko00000,ko00002,ko02000 Multidrug resistance protein
PGHHMJKG_01818 6.97e-126 ykkB - - J - - - COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGHHMJKG_01819 2.51e-125 ykkA - - S - - - Protein of unknown function (DUF664)
PGHHMJKG_01820 1.32e-165 ykjA - - S - - - Protein of unknown function (DUF421)
PGHHMJKG_01821 9.93e-15 - - - - - - - -
PGHHMJKG_01822 4.21e-286 hmp 1.14.12.17, 1.18.1.3 - C ko:K05916,ko:K15765 ko00623,ko00920,ko01100,ko01120,ko01220,ko05132,map00623,map00920,map01100,map01120,map01220,map05132 ko00000,ko00001,ko00002,ko01000 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PGHHMJKG_01823 5.42e-120 ykhA - - I - - - Acyl-CoA hydrolase
PGHHMJKG_01824 9.79e-102 ykgA - - E - - - Amidinotransferase
PGHHMJKG_01825 5.69e-261 pgl 3.1.1.31 - G ko:K07404 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconolactonase
PGHHMJKG_01826 8.44e-237 ykfD - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_01827 4.03e-207 ykfC 3.4.14.13 - M ko:K20742 - ko00000,ko01000,ko01002 COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PGHHMJKG_01828 3.21e-251 ykfB 5.1.1.20 - M ko:K19802 - ko00000,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PGHHMJKG_01829 5.33e-222 ykfA 3.4.17.13 - V ko:K01297 - ko00000,ko01000,ko01002,ko01011 proteins, homologs of microcin C7 resistance protein MccF
PGHHMJKG_01831 0.0 dppE - - E ko:K16199 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PGHHMJKG_01832 7.78e-236 dppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_01833 8.28e-222 dppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGHHMJKG_01834 9.7e-204 dppB - - P ko:K16200 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGHHMJKG_01835 1.4e-196 dppA - - E ko:K16203 - ko00000,ko01000,ko01002 D-aminopeptidase
PGHHMJKG_01837 0.0 yhgE - - S ko:K01421 - ko00000 YhgE Pip N-terminal domain protein
PGHHMJKG_01838 6.76e-131 yhgD - - K ko:K09017 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01839 0.0 hemY 1.3.3.15, 1.3.3.4 - H ko:K00231 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PGHHMJKG_01840 3.28e-229 hemH 4.99.1.1, 4.99.1.9 - H ko:K01772 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the ferrous insertion into protoporphyrin IX
PGHHMJKG_01841 1.24e-257 hemE 4.1.1.37 - H ko:K01599 ko00860,ko01100,ko01110,map00860,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PGHHMJKG_01842 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M ko:K12555 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PGHHMJKG_01843 1.31e-118 traP 1.14.99.57 - S ko:K21481 - ko00000,ko01000 enzyme involved in biosynthesis of extracellular polysaccharides
PGHHMJKG_01844 1e-44 - - - C - - - Rubrerythrin
PGHHMJKG_01845 3.86e-137 yhfA - - C - - - membrane
PGHHMJKG_01846 1.75e-142 yhfA - - C - - - membrane
PGHHMJKG_01847 1.27e-290 yhaA - - E ko:K01436 - ko00000,ko01000,ko01002 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PGHHMJKG_01848 2.89e-161 ecsC - - S - - - EcsC protein family
PGHHMJKG_01849 4.23e-270 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PGHHMJKG_01850 2.7e-176 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 transporter (ATP-binding protein)
PGHHMJKG_01851 3.5e-106 hit - - FG ko:K02503 - ko00000,ko04147 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PGHHMJKG_01852 1.84e-262 serC 2.6.1.52 - E ko:K00831 ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PGHHMJKG_01853 1.28e-103 trpP - - S - - - Tryptophan transporter TrpP
PGHHMJKG_01854 1.74e-54 yhaH - - S - - - YtxH-like protein
PGHHMJKG_01855 4.92e-148 hpr - - K ko:K09682 - ko00000,ko03000 Negative regulator of protease production and sporulation
PGHHMJKG_01856 1.2e-72 yhaI - - S - - - Protein of unknown function (DUF1878)
PGHHMJKG_01857 5.71e-116 yhaK - - S - - - Putative zincin peptidase
PGHHMJKG_01858 4.7e-161 prsA 5.2.1.8 - M ko:K01802,ko:K07533 - ko00000,ko01000,ko03110 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PGHHMJKG_01859 1.88e-39 yhaL - - S - - - Sporulation protein YhaL
PGHHMJKG_01860 5.22e-228 yhaM - - L ko:K03698 - ko00000,ko01000,ko03019 Shows a 3'-5' exoribonuclease activity
PGHHMJKG_01861 0.0 yhaN - - L - - - AAA domain
PGHHMJKG_01862 8.42e-302 yhaO - - L ko:K03547 - ko00000,ko03400 DNA repair exonuclease
PGHHMJKG_01863 5.14e-272 yhaP - - CP ko:K01992 - ko00000,ko00002,ko02000 COG1668 ABC-type Na efflux pump, permease component
PGHHMJKG_01864 5.56e-215 yhaQ - - S ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_01865 1.89e-35 - - - S - - - YhzD-like protein
PGHHMJKG_01866 1.45e-170 yhaR - - I - - - enoyl-CoA hydratase
PGHHMJKG_01868 6.51e-114 - - - P ko:K07228 - ko00000 regulatory, ligand-binding protein related to C-terminal domains of K channels
PGHHMJKG_01869 4.36e-266 yhaU - - P ko:K03455 - ko00000 COG0475 Kef-type K transport systems, membrane components
PGHHMJKG_01870 0.0 hemZ - - H - - - coproporphyrinogen III oxidase
PGHHMJKG_01871 8.7e-198 yhaX - - S - - - haloacid dehalogenase-like hydrolase
PGHHMJKG_01872 3.3e-92 yhaZ - - L - - - DNA alkylation repair enzyme
PGHHMJKG_01873 2.11e-131 yhaZ - - L - - - DNA alkylation repair enzyme
PGHHMJKG_01874 7.46e-72 yheA - - S - - - Belongs to the UPF0342 family
PGHHMJKG_01875 1.19e-258 yheB - - S - - - Belongs to the UPF0754 family
PGHHMJKG_01876 2.77e-275 yheC - - HJ - - - YheC/D like ATP-grasp
PGHHMJKG_01877 0.0 yheD - - HJ - - - YheC/D like ATP-grasp
PGHHMJKG_01878 2.27e-49 yheE - - S - - - Family of unknown function (DUF5342)
PGHHMJKG_01879 1.25e-38 sspB - - S ko:K06418,ko:K06419,ko:K06420 - ko00000 spore protein
PGHHMJKG_01880 1.29e-140 yheG - - GM - - - NAD(P)H-binding
PGHHMJKG_01881 0.0 yheH - - V ko:K06147,ko:K18217,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PGHHMJKG_01882 0.0 yheI - - V ko:K18216,ko:K18889 ko02010,map02010 ko00000,ko00001,ko00002,ko01504,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PGHHMJKG_01883 1.53e-108 nhaX - - T - - - Belongs to the universal stress protein A family
PGHHMJKG_01884 3.45e-301 nhaC - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PGHHMJKG_01885 2.6e-196 dat 2.6.1.21 - E ko:K00824 ko00310,ko00330,ko00360,ko00472,ko00473,ko01100,map00310,map00330,map00360,map00472,map00473,map01100 ko00000,ko00001,ko01000,ko01007 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PGHHMJKG_01886 9.72e-192 nodB1 - - G - - - deacetylase
PGHHMJKG_01887 9.4e-177 cobB - - K ko:K12410 - ko00000,ko01000 NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PGHHMJKG_01888 1.06e-258 yhdY - - M ko:K16052 - ko00000,ko02000 Mechanosensitive ion channel
PGHHMJKG_01889 3.7e-09 yhdX - - S - - - Uncharacterized protein YhdX
PGHHMJKG_01890 9.03e-173 yhdW 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PGHHMJKG_01891 5.83e-87 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGHHMJKG_01892 2.48e-66 crcB - - D ko:K06199 - ko00000,ko02000 Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PGHHMJKG_01893 0.0 yhdT - - P - - - COG1253 Hemolysins and related proteins containing CBS domains
PGHHMJKG_01894 3.62e-171 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PGHHMJKG_01895 3.35e-92 yhdR 2.6.1.1 - E ko:K11358 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PGHHMJKG_01896 3.44e-97 cueR - - K ko:K11923 - ko00000,ko03000 transcriptional
PGHHMJKG_01897 2.18e-304 yhdP - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PGHHMJKG_01898 3.9e-143 plsC 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PGHHMJKG_01899 1.12e-242 yhdN - - C - - - Aldo keto reductase
PGHHMJKG_01900 3.24e-113 sigM - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_01901 2.05e-256 yhdL - - S - - - Sigma factor regulator N-terminal
PGHHMJKG_01902 4.27e-59 yhdK - - S - - - Sigma-M inhibitor protein
PGHHMJKG_01903 1.75e-100 - - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_01904 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGHHMJKG_01905 2.89e-308 yhdH - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PGHHMJKG_01906 8.94e-317 yhdG - - E ko:K03294 - ko00000 amino acid
PGHHMJKG_01907 3.72e-204 yhdF - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_01908 1.45e-258 citA 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PGHHMJKG_01909 4.93e-210 citR - - K ko:K19242 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_01910 7.21e-204 lytE - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PGHHMJKG_01911 0.0 phoB 3.1.3.1 - P ko:K01077 ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko00537,ko01000,ko04147 Belongs to the alkaline phosphatase family
PGHHMJKG_01912 0.0 spoVR - - S ko:K06415 - ko00000 Stage V sporulation protein R
PGHHMJKG_01913 5.04e-305 ygxB - - M - - - Conserved TM helix
PGHHMJKG_01914 0.0 sqhC 4.2.1.137 - I ko:K18115 - ko00000,ko01000 COG1657 Squalene cyclase
PGHHMJKG_01915 1.3e-206 sodF 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 Superoxide dismutase
PGHHMJKG_01916 3.57e-299 yocR - - S ko:K03308 - ko00000 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PGHHMJKG_01917 5.48e-213 yocS - - S ko:K03453 - ko00000 -transporter
PGHHMJKG_01918 1.05e-263 odhB 2.3.1.61 - C ko:K00658 ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PGHHMJKG_01919 0.0 odhA 1.2.4.2 - C ko:K00164 ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PGHHMJKG_01920 0.0 yojO - - P - - - Von Willebrand factor
PGHHMJKG_01921 7.38e-205 yojN - - S ko:K04748 - ko00000 ATPase family associated with various cellular activities (AAA)
PGHHMJKG_01922 4.94e-140 sodC 1.15.1.1 - P ko:K04565 ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020 ko00000,ko00001,ko01000 Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PGHHMJKG_01923 2.48e-262 - - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PGHHMJKG_01924 3.12e-291 yojK - - CG - - - UDP-glucoronosyl and UDP-glucosyl transferase
PGHHMJKG_01925 2.14e-141 dacB 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGHHMJKG_01927 2.93e-313 norM - - V ko:K03327 - ko00000,ko02000 Multidrug efflux pump
PGHHMJKG_01928 2.91e-193 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PGHHMJKG_01929 1.84e-161 yojG - - S ko:K22135 - ko00000,ko01000 deacetylase
PGHHMJKG_01930 2.32e-79 yojF - - S - - - Protein of unknown function (DUF1806)
PGHHMJKG_01931 1.85e-58 - - - - - - - -
PGHHMJKG_01932 6.68e-207 rarD - - S ko:K05786 - ko00000,ko02000 -transporter
PGHHMJKG_01933 8.34e-104 yozR - - S - - - COG0071 Molecular chaperone (small heat shock protein)
PGHHMJKG_01934 1.13e-13 - - - - - - - -
PGHHMJKG_01935 3.6e-287 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PGHHMJKG_01936 5.64e-84 iolK - - S - - - tautomerase
PGHHMJKG_01937 2.63e-73 yodB - - K - - - transcriptional
PGHHMJKG_01938 1.92e-140 yodC - - C - - - nitroreductase
PGHHMJKG_01939 2.17e-145 yahD - - S ko:K06999 - ko00000 Carboxylesterase
PGHHMJKG_01940 5.61e-222 yodE - - E ko:K15975 - ko00000 COG0346 Lactoylglutathione lyase and related lyases
PGHHMJKG_01941 3.36e-38 - - - S - - - Protein of unknown function (DUF3311)
PGHHMJKG_01942 0.0 yodF - - E ko:K03307 - ko00000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGHHMJKG_01943 0.0 ctpA 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PGHHMJKG_01944 3.03e-166 yodH - - Q - - - Methyltransferase
PGHHMJKG_01945 2.81e-40 yodI - - - - - - -
PGHHMJKG_01946 7.71e-189 yodJ 3.4.17.14 - M ko:K07260 ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504 D-alanyl-D-alanine carboxypeptidase
PGHHMJKG_01947 1.68e-163 deoD 2.4.2.1 - F ko:K03784 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Purine nucleoside phosphorylase
PGHHMJKG_01948 2.08e-12 - - - - - - - -
PGHHMJKG_01949 1.17e-71 yodL - - S - - - YodL-like
PGHHMJKG_01950 5.26e-134 yodM 3.6.1.27 - I ko:K19302 ko00550,map00550 ko00000,ko00001,ko01000,ko01011 Acid phosphatase homologues
PGHHMJKG_01951 5.18e-34 yozD - - S - - - YozD-like protein
PGHHMJKG_01953 7.44e-159 yodN - - - - - - -
PGHHMJKG_01954 2.1e-49 yozE - - S - - - Belongs to the UPF0346 family
PGHHMJKG_01955 3.44e-63 yokU - - S - - - YokU-like protein, putative antitoxin
PGHHMJKG_01956 0.0 kamA 5.4.3.2 - E ko:K01843 ko00310,map00310 ko00000,ko00001,ko01000 lysine 2,3-aminomutase
PGHHMJKG_01957 3.56e-195 yodP 2.3.1.264 - K ko:K21935 - ko00000,ko01000 Acetyltransferase (GNAT) family
PGHHMJKG_01958 0.0 yodQ 3.5.1.16, 3.5.1.18 - E ko:K01438,ko:K01439 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Acetylornithine deacetylase
PGHHMJKG_01959 3.66e-78 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PGHHMJKG_01960 1.15e-58 atoA 2.8.3.8, 2.8.3.9 - I ko:K01035 ko00310,ko00627,ko00640,ko00650,ko01100,ko01120,ko02020,map00310,map00627,map00640,map00650,map01100,map01120,map02020 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PGHHMJKG_01962 3.85e-314 yodT - - H - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGHHMJKG_01964 1.97e-184 yiiD - - K ko:K06323 - ko00000 acetyltransferase
PGHHMJKG_01965 0.0 cgeD - - M ko:K06322 - ko00000 maturation of the outermost layer of the spore
PGHHMJKG_01966 1.76e-58 cgeC - - - ko:K06321 - ko00000 -
PGHHMJKG_01967 3.62e-82 cgeA - - - ko:K06319 - ko00000 -
PGHHMJKG_01968 4.45e-226 cgeB - - S ko:K06320 - ko00000 Spore maturation protein
PGHHMJKG_01969 1.34e-278 phy 3.1.3.8 - I ko:K01083 ko00562,map00562 ko00000,ko00001,ko01000 Myo-inositol-hexaphosphate 3-phosphohydrolase
PGHHMJKG_01970 5.51e-156 - - - GM ko:K19421 - ko00000 Polysaccharide biosynthesis protein
PGHHMJKG_01971 7.13e-103 msrB 1.8.4.12 - O ko:K07305 - ko00000,ko01000 peptide methionine sulfoxide reductase
PGHHMJKG_01972 9.83e-133 msrB 1.8.4.11, 1.8.4.12 - O ko:K07304,ko:K12267 - ko00000,ko01000 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PGHHMJKG_01973 4.14e-94 ypoP - - K - - - transcriptional
PGHHMJKG_01974 1.65e-288 mepA - - V - - - MATE efflux family protein
PGHHMJKG_01975 1.24e-39 ypmT - - S - - - Uncharacterized ympT
PGHHMJKG_01976 4.59e-127 ypmS - - S - - - protein conserved in bacteria
PGHHMJKG_01977 2.58e-178 ypmR - - E - - - GDSL-like Lipase/Acylhydrolase
PGHHMJKG_01978 1.24e-135 ypmQ - - S ko:K07152 - ko00000,ko03029 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PGHHMJKG_01979 1.28e-54 ypmP - - S - - - Protein of unknown function (DUF2535)
PGHHMJKG_01980 1.04e-309 ilvA 4.3.1.19 - E ko:K01754 ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PGHHMJKG_01981 5.47e-234 yplP - - K - - - Transcriptional regulator
PGHHMJKG_01982 6.6e-142 yplQ - - S ko:K11068 - ko00000,ko02042 protein, Hemolysin III
PGHHMJKG_01983 4.7e-143 ypkP 2.3.1.51 - I ko:K00655 ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PGHHMJKG_01984 7.88e-121 dfrA 1.5.1.3 - H ko:K00287 ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PGHHMJKG_01985 1.8e-120 ltrC 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PGHHMJKG_01986 2.01e-147 ypjP - - S - - - YpjP-like protein
PGHHMJKG_01987 5.05e-186 ypiP - - AJ - - - Putative SAM-dependent methyltransferase
PGHHMJKG_01988 9.69e-99 yphP - - S - - - Belongs to the UPF0403 family
PGHHMJKG_01989 0.0 ilvD 4.2.1.9 - E ko:K01687,ko:K16786 ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,ko02010,map00290,map00770,map01100,map01110,map01130,map01210,map01230,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the IlvD Edd family
PGHHMJKG_01990 8.52e-206 ypgR - - C - - - COG0694 Thioredoxin-like proteins and domains
PGHHMJKG_01991 7.22e-142 yagB - - S ko:K06950 - ko00000 phosphohydrolase
PGHHMJKG_01992 5.2e-113 bsaA 1.11.1.9 - O ko:K00432 ko00480,ko00590,ko04918,map00480,map00590,map04918 ko00000,ko00001,ko01000 Belongs to the glutathione peroxidase family
PGHHMJKG_01993 1.01e-223 metAA 2.3.1.46 - E ko:K00651 ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PGHHMJKG_01994 1.28e-276 ugtP 2.4.1.315 GT28 M ko:K03429 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000,ko01003 Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PGHHMJKG_01995 2.54e-42 cspD - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PGHHMJKG_01996 1.17e-22 degR - - - - - - -
PGHHMJKG_01997 1.05e-40 - - - S - - - Protein of unknown function (DUF2564)
PGHHMJKG_01998 1.54e-37 ypeQ - - S - - - Zinc-finger
PGHHMJKG_01999 1.56e-160 ypeP 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 COG0328 Ribonuclease HI
PGHHMJKG_02000 6.59e-136 ypdP - - S ko:K09125 - ko00000 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PGHHMJKG_02001 1.27e-86 rnhA 3.1.26.4 - L ko:K03469 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Ribonuclease
PGHHMJKG_02002 2.59e-05 - - - - ko:K06429 - ko00000 -
PGHHMJKG_02003 2.26e-213 ypcP - - L - - - 5'3' exonuclease
PGHHMJKG_02004 1.08e-11 - - - - - - - -
PGHHMJKG_02005 1.66e-51 ypbS - - S - - - Protein of unknown function (DUF2533)
PGHHMJKG_02006 0.0 ypbR - - S - - - Dynamin family
PGHHMJKG_02007 1.36e-112 ypbQ - - S ko:K16168 - ko00000,ko01008 protein conserved in bacteria
PGHHMJKG_02008 4.08e-41 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
PGHHMJKG_02009 1.49e-201 bcsA - - Q ko:K16167 - ko00000,ko01008 Naringenin-chalcone synthase
PGHHMJKG_02010 8.61e-292 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
PGHHMJKG_02011 9.13e-126 xpt 2.4.2.22 - F ko:K03816 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PGHHMJKG_02012 0.0 ypwA 3.4.17.19 - E ko:K01299 - ko00000,ko01000,ko01002 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PGHHMJKG_02013 2.36e-223 kdgT - - P ko:K02526 - ko00000,ko02000 The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
PGHHMJKG_02014 5.97e-132 kdgA 4.1.2.14, 4.1.3.42 - G ko:K01625 ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 2-dehydro-3-deoxy-phosphogluconate aldolase
PGHHMJKG_02015 1.15e-236 kdgK 2.7.1.45 - G ko:K00874 ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0524 Sugar kinases, ribokinase family
PGHHMJKG_02016 2.24e-237 kdgR - - K ko:K02525 - ko00000,ko03000 transcriptional
PGHHMJKG_02017 7.26e-204 kduI 5.3.1.17 - G ko:K01815 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PGHHMJKG_02018 3.12e-174 kduD 1.1.1.127 - IQ ko:K00065 ko00040,map00040 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_02019 0.0 ypvA 3.6.4.12 - KL ko:K03722 - ko00000,ko01000,ko03400 COG1199 Rad3-related DNA helicases
PGHHMJKG_02021 1.16e-285 ypsC - - L ko:K07444 - ko00000,ko01000 Belongs to the methyltransferase superfamily
PGHHMJKG_02022 2.97e-60 gpsB - - D - - - Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PGHHMJKG_02023 1.39e-127 ypsA - - S - - - Belongs to the UPF0398 family
PGHHMJKG_02024 2.81e-298 yprB - - L ko:K07502 - ko00000 RNase_H superfamily
PGHHMJKG_02025 0.0 yprA - - L ko:K06877 - ko00000 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PGHHMJKG_02026 2.59e-110 ypqE - - G ko:K02777 ko00010,ko00500,ko00520,ko02026,ko02060,ko05111,map00010,map00500,map00520,map02026,map02060,map05111 ko00000,ko00001,ko00002,ko01000,ko02000 COG2190 Phosphotransferase system IIA components
PGHHMJKG_02027 2.41e-92 hspX - - O ko:K06335,ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Belongs to the small heat shock protein (HSP20) family
PGHHMJKG_02028 8.36e-66 yppG - - S - - - YppG-like protein
PGHHMJKG_02029 9.21e-11 - - - S - - - YppF-like protein
PGHHMJKG_02030 7.9e-10 yppE - - S - - - Bacterial domain of unknown function (DUF1798)
PGHHMJKG_02033 2.52e-238 yppC - - S - - - Protein of unknown function (DUF2515)
PGHHMJKG_02034 1.3e-149 recU - - L ko:K03700 - ko00000,ko03400 Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PGHHMJKG_02035 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M ko:K05366 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01003,ko01011 penicillin-binding protein
PGHHMJKG_02036 1.43e-121 ypoC - - - - - - -
PGHHMJKG_02037 3.57e-158 nth 4.2.99.18 - L ko:K10773 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PGHHMJKG_02038 6.62e-165 dnaD - - L ko:K02086 - ko00000 DNA replication protein DnaD
PGHHMJKG_02039 0.0 asnS 6.1.1.22 - J ko:K01893 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 asparaginyl-tRNA
PGHHMJKG_02040 4.37e-285 aspB 2.6.1.1, 2.6.1.14 - E ko:K00812,ko:K22457 ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko01000,ko01007 Aminotransferase
PGHHMJKG_02041 2.66e-102 ypmB - - S - - - protein conserved in bacteria
PGHHMJKG_02042 1.52e-32 ypmA - - S - - - Protein of unknown function (DUF4264)
PGHHMJKG_02043 0.0 dinG 3.6.4.12 - L ko:K03722 - ko00000,ko01000,ko03400 helicase involved in DNA repair and perhaps also replication
PGHHMJKG_02044 4.16e-85 panD 4.1.1.11 - H ko:K01579 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PGHHMJKG_02045 1.57e-199 panC 6.3.2.1 - H ko:K01918 ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PGHHMJKG_02046 9.79e-194 panB 2.1.2.11 - H ko:K00606 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PGHHMJKG_02047 6.91e-234 birA 6.3.4.15 - K ko:K03524 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko01000,ko03000 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PGHHMJKG_02048 1.83e-279 cca 2.7.7.72 - J ko:K00974 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PGHHMJKG_02049 2.45e-267 bshA - GT4 M ko:K00754 - ko00000,ko01000 N-acetyl-alpha-D-glucosaminyl L-malate synthase
PGHHMJKG_02050 2.21e-165 bshB1 - - S ko:K01463 - ko00000,ko01000 proteins, LmbE homologs
PGHHMJKG_02051 2.52e-93 mgsA 4.2.3.3 - G ko:K01734 ko00640,ko01120,map00640,map01120 ko00000,ko00001,ko01000 methylglyoxal synthase
PGHHMJKG_02052 2.4e-189 dapB 1.17.1.8 - E ko:K00215 ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PGHHMJKG_02053 1.01e-73 ypjD - - S - - - Nucleotide pyrophosphohydrolase
PGHHMJKG_02054 3.7e-200 ypjC - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PGHHMJKG_02055 6.56e-181 ypjB - - S - - - sporulation protein
PGHHMJKG_02056 1.15e-125 ypjA - - S - - - membrane
PGHHMJKG_02057 5.71e-191 qcrC - - C ko:K03888 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 Menaquinol-cytochrome c reductase cytochrome b c subunit
PGHHMJKG_02058 8.76e-166 qcrB - - C ko:K03887 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002 COG1290 Cytochrome b subunit of the bc complex
PGHHMJKG_02059 3.35e-126 qcrA - - C ko:K03886 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Menaquinol-cytochrome c reductase
PGHHMJKG_02060 5.55e-100 ypiF - - S - - - Protein of unknown function (DUF2487)
PGHHMJKG_02061 1.29e-129 ypiB - - S - - - Belongs to the UPF0302 family
PGHHMJKG_02062 3.56e-297 ypiA - - S - - - COG0457 FOG TPR repeat
PGHHMJKG_02063 9.49e-300 aroA 2.5.1.19 - E ko:K00800 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PGHHMJKG_02064 1.21e-264 tyrA 1.3.1.12 - E ko:K04517 ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 prephenate dehydrogenase
PGHHMJKG_02065 2.6e-258 hisC 2.6.1.9 - E ko:K00817 ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PGHHMJKG_02066 3.14e-185 trpA 4.2.1.20 - E ko:K01695 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PGHHMJKG_02067 1.09e-293 trpB 4.2.1.20, 5.3.1.24 - E ko:K01696,ko:K01817 ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PGHHMJKG_02068 2.6e-149 trpF 5.3.1.24 - E ko:K01817 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpF family
PGHHMJKG_02069 2.95e-145 trpC 4.1.1.48, 5.3.1.24 - E ko:K01609,ko:K13498 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the TrpC family
PGHHMJKG_02070 2.37e-227 trpD 2.4.2.18, 4.1.3.27 - E ko:K00766,ko:K13497 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PGHHMJKG_02071 0.0 trpE 4.1.3.27 - EH ko:K01657 ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025 ko00000,ko00001,ko00002,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGHHMJKG_02072 9.82e-84 aroH 5.4.99.5 - E ko:K06208 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PGHHMJKG_02073 3.86e-261 aroB 4.2.3.4 - E ko:K01735 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PGHHMJKG_02074 5.88e-277 aroC 4.2.3.5 - E ko:K01736 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PGHHMJKG_02075 3.69e-183 cheR 2.1.1.80 - NT ko:K00575 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko01000,ko02035 COG1352 Methylase of chemotaxis methyl-accepting proteins
PGHHMJKG_02076 2.17e-104 ndk 2.7.4.6 - F ko:K00940 ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016 ko00000,ko00001,ko00002,ko01000,ko04131 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PGHHMJKG_02077 4.09e-249 hepT 2.5.1.30, 2.5.1.83 - H ko:K00805,ko:K21275 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PGHHMJKG_02078 5.46e-169 menG 2.1.1.163, 2.1.1.201 - H ko:K03183 ko00130,ko01100,ko01110,map00130,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PGHHMJKG_02079 7.17e-177 hepS 2.5.1.30 - H ko:K00805 ko00900,ko01110,map00900,map01110 ko00000,ko00001,ko01000,ko01006 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PGHHMJKG_02080 5.13e-46 mtrB - - K ko:K06285 - ko00000,ko03000 Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PGHHMJKG_02081 4.41e-131 folE 3.5.4.16 - H ko:K01495 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 GTP cyclohydrolase
PGHHMJKG_02082 1.54e-217 cysK 2.5.1.47 - E ko:K01738 ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the cysteine synthase cystathionine beta- synthase family
PGHHMJKG_02083 2.41e-204 yacD 5.2.1.8 - O ko:K07533 - ko00000,ko01000,ko03110 peptidyl-prolyl isomerase
PGHHMJKG_02084 9.54e-208 hslO - - O ko:K04083 - ko00000,ko03110 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PGHHMJKG_02085 6.92e-189 coaX 2.7.1.33 - F ko:K03525 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PGHHMJKG_02086 0.0 ftsH - - O ko:K03798 - ko00000,ko00002,ko01000,ko01002,ko03110 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PGHHMJKG_02087 4.82e-121 hpt 2.4.2.8, 6.3.4.19 - F ko:K00760,ko:K15780 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Belongs to the purine pyrimidine phosphoribosyltransferase family
PGHHMJKG_02088 0.0 tilS 2.4.2.8, 6.3.4.19 - D ko:K04075,ko:K15780 ko00230,ko01100,ko01110,map00230,map01100,map01110 ko00000,ko00001,ko01000,ko03016 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PGHHMJKG_02089 6.63e-234 yabT 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 serine threonine protein kinase
PGHHMJKG_02090 5.61e-168 yabS - - S ko:K07114 - ko00000,ko02000 protein containing a von Willebrand factor type A (vWA) domain
PGHHMJKG_02091 0.0 spoIIE 3.1.3.16 - KT ko:K06382 - ko00000,ko01000 stage II sporulation protein E
PGHHMJKG_02094 2.49e-82 yabR - - J ko:K07571 - ko00000 RNA binding protein (contains ribosomal protein S1 domain)
PGHHMJKG_02095 4.18e-75 divIC - - D ko:K13052 - ko00000,ko03036 Septum formation initiator
PGHHMJKG_02096 2.58e-138 yabQ - - S - - - spore cortex biosynthesis protein
PGHHMJKG_02097 1.91e-66 yabP - - S - - - Sporulation protein YabP
PGHHMJKG_02098 4.22e-50 yabO - - J - - - COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PGHHMJKG_02099 0.0 yabN 3.6.1.66 - S ko:K02428,ko:K02499 ko00230,map00230 ko00000,ko00001,ko01000,ko03036 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PGHHMJKG_02100 0.0 yabM - - S ko:K03328 - ko00000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGHHMJKG_02101 5.88e-121 spoVT - - K ko:K04769 - ko00000,ko03000 stage V sporulation protein
PGHHMJKG_02102 0.0 mfd - - L ko:K03723 ko03420,map03420 ko00000,ko00001,ko01000,ko03400 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PGHHMJKG_02103 6.36e-54 yabK - - S - - - Peptide ABC transporter permease
PGHHMJKG_02104 2.03e-135 pth 3.1.1.29 - J ko:K01056 - ko00000,ko01000,ko03012 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PGHHMJKG_02105 1.69e-135 ctc - - J ko:K02897 ko03010,map03010 ko00000,ko00001,ko00002,ko03011 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PGHHMJKG_02106 7.08e-223 prs 2.7.6.1 - F ko:K00948 ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PGHHMJKG_02107 1.49e-308 glmU 2.3.1.157, 2.7.7.23 - M ko:K04042 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PGHHMJKG_02108 2.45e-63 spoVG - - D ko:K06412 - ko00000 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PGHHMJKG_02109 3.45e-83 yabJ 3.5.99.10 - J ko:K09022 - ko00000,ko01000 translation initiation inhibitor, yjgF family
PGHHMJKG_02110 3.82e-195 purR - - F ko:K09685 - ko00000,ko03000 pur operon repressor
PGHHMJKG_02111 9.53e-207 ispE 2.7.1.148 - I ko:K00919,ko:K16924 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko02000 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PGHHMJKG_02112 3.96e-37 sspF - - S ko:K06423 - ko00000 DNA topological change
PGHHMJKG_02113 5.32e-53 veg - - S - - - protein conserved in bacteria
PGHHMJKG_02114 1.11e-198 yabG - - S ko:K06436 - ko00000 peptidase
PGHHMJKG_02115 1.24e-199 ksgA 2.1.1.182 - J ko:K02528 - ko00000,ko01000,ko03009 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PGHHMJKG_02116 2.46e-126 rnmV 3.1.26.8 - J ko:K05985 - ko00000,ko01000 Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PGHHMJKG_02117 1.18e-277 yabE - - T - - - protein conserved in bacteria
PGHHMJKG_02118 5.9e-184 tatD - - L ko:K03424 - ko00000,ko01000 hydrolase, TatD
PGHHMJKG_02119 0.0 metG 6.1.1.10 - J ko:K01874 ko00450,ko00970,map00450,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PGHHMJKG_02120 1.51e-58 abrB - - K ko:K06284 - ko00000,ko03000 COG2002 Regulators of stationary sporulation gene expression
PGHHMJKG_02121 2.95e-207 rsmI 2.1.1.198 - H ko:K07056 - ko00000,ko01000,ko03009 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PGHHMJKG_02122 2.84e-63 yazA - - L ko:K07461 - ko00000 endonuclease containing a URI domain
PGHHMJKG_02123 4.66e-177 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Conserved hypothetical protein 95
PGHHMJKG_02124 8.82e-56 yabA - - L - - - Involved in initiation control of chromosome replication
PGHHMJKG_02125 6.33e-189 yaaT - - S - - - stage 0 sporulation protein
PGHHMJKG_02126 2.82e-235 holB 2.7.7.7 - L ko:K02341 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III
PGHHMJKG_02127 1.26e-95 yaaR - - S ko:K09770 - ko00000 protein conserved in bacteria
PGHHMJKG_02128 1.02e-72 yaaQ - - S - - - protein conserved in bacteria
PGHHMJKG_02129 4.67e-146 tmk 2.7.4.9 - F ko:K00943 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PGHHMJKG_02130 0.0 yaaO - - E - - - Orn Lys Arg decarboxylase
PGHHMJKG_02131 1.19e-258 yaaN - - P - - - Belongs to the TelA family
PGHHMJKG_02132 6.08e-129 xpaC - - S - - - 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PGHHMJKG_02133 2.21e-42 csfB - - S - - - Inhibitor of sigma-G Gin
PGHHMJKG_02134 2.23e-90 - - - S - - - Regulatory protein YrvL
PGHHMJKG_02135 9.3e-126 ymcC - - S - - - Membrane
PGHHMJKG_02136 1.02e-134 pksA - - K - - - Transcriptional regulator
PGHHMJKG_02137 8.03e-81 ymzB - - - - - - -
PGHHMJKG_02138 6.55e-208 - - - S - - - Metallo-beta-lactamase superfamily
PGHHMJKG_02139 0.0 aprX - - O ko:K17734 - ko00000,ko01000,ko01002 Belongs to the peptidase S8 family
PGHHMJKG_02141 3.96e-163 ymaC - - S - - - Replication protein
PGHHMJKG_02142 1.03e-105 ymaD - - O - - - redox protein, regulator of disulfide bond formation
PGHHMJKG_02143 1.57e-73 ebrB - - P ko:K03297,ko:K11814,ko:K11815 - ko00000,ko00002,ko02000 COG2076 Membrane transporters of cations and cationic drugs
PGHHMJKG_02144 2.45e-67 ebrA - - P ko:K11814 - ko00000,ko00002,ko02000 Small Multidrug Resistance protein
PGHHMJKG_02146 5.41e-76 ymaF - - S - - - YmaF family
PGHHMJKG_02147 3.95e-223 miaA 2.5.1.75 - J ko:K00791 ko00908,ko01100,ko01110,map00908,map01100,map01110 ko00000,ko00001,ko01000,ko01006,ko03016 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PGHHMJKG_02148 1.28e-45 hfq - - J ko:K03666 ko02024,ko03018,ko05111,map02024,map03018,map05111 ko00000,ko00001,ko03019,ko03036 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PGHHMJKG_02149 1.63e-31 - - - - - - - -
PGHHMJKG_02150 1.2e-30 ymzA - - - - - - -
PGHHMJKG_02151 5.01e-66 nrdI - - F ko:K03647 - ko00000 Probably involved in ribonucleotide reductase function
PGHHMJKG_02152 0.0 nrdE 1.17.4.1 - F ko:K00525 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGHHMJKG_02153 1.65e-243 nrdF 1.17.4.1 - F ko:K00526 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PGHHMJKG_02154 2.24e-141 - - - - - - - -
PGHHMJKG_02155 1.16e-149 cwlC 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 n-acetylmuramoyl-L-alanine amidase
PGHHMJKG_02156 2.29e-226 spoVK - - O ko:K06413 - ko00000 stage V sporulation protein K
PGHHMJKG_02157 1.82e-293 hflX - - S ko:K03665 - ko00000,ko03009 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PGHHMJKG_02158 1.37e-309 ynbB - - P - - - COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PGHHMJKG_02159 9.94e-90 glnR - - K ko:K03713,ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000,ko03000 transcriptional
PGHHMJKG_02160 0.0 glnA 6.3.1.2 - E ko:K01915 ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727 ko00000,ko00001,ko01000,ko04147 glutamine synthetase
PGHHMJKG_02161 3.69e-32 - - - - - - - -
PGHHMJKG_02162 1.68e-53 - - - - - - - -
PGHHMJKG_02163 4.6e-309 - - - M - - - nucleic acid phosphodiester bond hydrolysis
PGHHMJKG_02165 1.68e-13 - - - - - - - -
PGHHMJKG_02167 2.93e-105 - - - - - - - -
PGHHMJKG_02168 4.13e-51 - - - - - - - -
PGHHMJKG_02169 4.13e-116 - - - G - - - SMI1-KNR4 cell-wall
PGHHMJKG_02170 9.3e-51 ynaC - - - - - - -
PGHHMJKG_02171 3.65e-81 ynaC - - - - - - -
PGHHMJKG_02173 5.58e-99 nsrR - - K ko:K13771 ko05132,map05132 ko00000,ko00001,ko03000 Transcriptional regulator
PGHHMJKG_02174 1.32e-272 lytF - CBM50 M ko:K19220,ko:K19223,ko:K19224 - ko00000,ko01000,ko01002,ko01011 COG1388 FOG LysM repeat
PGHHMJKG_02175 1.02e-71 yhdC - - S - - - Protein of unknown function (DUF3889)
PGHHMJKG_02176 1.65e-51 yhdB - - S - - - YhdB-like protein
PGHHMJKG_02177 1.9e-115 yhdA 1.7.1.6 - S ko:K03206 - ko00000,ko01000 NADPH-dependent FMN reductase
PGHHMJKG_02178 9.41e-145 yhcZ - - K ko:K02479 - ko00000,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_02179 1.54e-271 yhcY 2.7.13.3 - T ko:K02480 - ko00000,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_02180 0.0 pgcA 5.4.2.2 - G ko:K01835 ko00010,ko00030,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Phosphoglucomutase
PGHHMJKG_02181 0.0 glpD 1.1.3.21, 1.1.5.3 - C ko:K00105,ko:K00111 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PGHHMJKG_02182 0.0 glpK 2.7.1.30 - C ko:K00864 ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626 ko00000,ko00001,ko01000,ko04147 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PGHHMJKG_02183 5.7e-196 glpF - - G ko:K02440 - ko00000,ko02000 Belongs to the MIP aquaporin (TC 1.A.8) family
PGHHMJKG_02184 5.35e-135 glpP - - K ko:K02443 - ko00000,ko03000 Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PGHHMJKG_02185 0.0 yhxA - - E - - - Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGHHMJKG_02186 0.0 yhcX - - K - - - Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PGHHMJKG_02187 1.24e-154 yhcW - - S ko:K07025 - ko00000 hydrolase
PGHHMJKG_02188 7.16e-90 yhcV - - S - - - COG0517 FOG CBS domain
PGHHMJKG_02189 4.27e-89 yhcU - - S - - - Family of unknown function (DUF5365)
PGHHMJKG_02190 8.26e-219 rluA 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PGHHMJKG_02191 1.25e-134 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
PGHHMJKG_02192 0.0 yhcR 3.1.3.5, 3.1.3.6, 3.1.4.16 - F ko:K01081,ko:K01119,ko:K08693 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PGHHMJKG_02193 7.05e-124 yhcQ - - M - - - Spore coat protein
PGHHMJKG_02194 3.38e-216 yhcP - - - - - - -
PGHHMJKG_02195 9.32e-108 yhcN - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PGHHMJKG_02196 9.39e-63 yhcM - - - - - - -
PGHHMJKG_02198 2.45e-83 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_02199 2.1e-71 - - - S - - - Domain of unknown function (DUF4145)
PGHHMJKG_02200 3.04e-87 yddJ - - S - - - Domain of unknown function with cystatin-like fold (DUF4467)
PGHHMJKG_02201 3.19e-111 yddI - - - - - - -
PGHHMJKG_02202 1.03e-237 yddH - - M - - - Lysozyme-like
PGHHMJKG_02203 0.0 yddG - - S - - - maturation of SSU-rRNA
PGHHMJKG_02204 1.1e-71 - - - S - - - Domain of unknown function (DUF1874)
PGHHMJKG_02205 2.21e-242 yddE - - S - - - AAA-like domain
PGHHMJKG_02206 1.59e-270 yddE - - S - - - AAA-like domain
PGHHMJKG_02207 6.91e-118 yddD - - S - - - TcpE family
PGHHMJKG_02208 9.78e-54 yddC - - - - - - -
PGHHMJKG_02209 2.61e-223 yddB - - S - - - Conjugative transposon protein TcpC
PGHHMJKG_02213 4.39e-37 yddA - - - - - - -
PGHHMJKG_02215 6.72e-60 ydcL - - L - - - Belongs to the 'phage' integrase family
PGHHMJKG_02219 1.5e-81 - - - S - - - Immunity protein 70
PGHHMJKG_02220 1.22e-249 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
PGHHMJKG_02221 2.62e-301 tcyP - - U ko:K06956 - ko00000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGHHMJKG_02222 4.78e-249 yhcK 2.7.7.65 - T ko:K18967 - ko00000,ko01000,ko02000 COG2199 FOG GGDEF domain
PGHHMJKG_02223 4.31e-192 metQ_3 - - M ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the nlpA lipoprotein family
PGHHMJKG_02224 1.91e-42 cspB - - K ko:K03704 - ko00000,ko03000 Cold-shock protein
PGHHMJKG_02225 5.71e-211 yhcI - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PGHHMJKG_02226 5.09e-210 yhcH - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_02227 1.32e-155 yhcG - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_02228 1.95e-78 yhcF - - K ko:K07979 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_02229 2.06e-69 - - - - - - - -
PGHHMJKG_02230 3.95e-59 yhcC - - - - - - -
PGHHMJKG_02231 1.4e-127 yhcB 1.6.5.2 - S ko:K03809 ko00130,ko01110,map00130,map01110 ko00000,ko00001,ko01000 Belongs to the WrbA family
PGHHMJKG_02232 0.0 yhcA - - EGP ko:K03446 - ko00000,ko00002,ko02000 the major facilitator superfamily
PGHHMJKG_02233 2.67e-133 yhbJ - - V - - - COG1566 Multidrug resistance efflux pump
PGHHMJKG_02234 1.29e-101 yhbI - - K ko:K15973 - ko00000,ko03000 DNA-binding transcription factor activity
PGHHMJKG_02235 1.21e-286 yhbH - - S ko:K09786 - ko00000 Belongs to the UPF0229 family
PGHHMJKG_02236 0.0 prkA - - T ko:K07180 - ko00000 Ser protein kinase
PGHHMJKG_02237 3.01e-105 yhbF - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PGHHMJKG_02238 1.53e-94 yhbE - - M - - - COG1664 Integral membrane protein CcmA involved in cell shape determination
PGHHMJKG_02239 3.97e-142 yhbD - - K - - - Protein of unknown function (DUF4004)
PGHHMJKG_02240 1.08e-111 cspR 2.1.1.207 - J ko:K03216 - ko00000,ko01000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PGHHMJKG_02241 9.27e-224 yhbB - - S - - - Putative amidase domain
PGHHMJKG_02242 1.7e-283 queG 1.17.99.6 - C ko:K18979 - ko00000,ko01000,ko03016 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PGHHMJKG_02243 1.07e-144 yhzB - - S - - - B3/4 domain
PGHHMJKG_02245 1.48e-39 - - - K ko:K07729 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_02246 6.32e-99 ygaO - - - - - - -
PGHHMJKG_02247 1.96e-54 rpsN - - J ko:K02954 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PGHHMJKG_02250 8.96e-274 ssuD 1.14.14.28, 1.14.14.5 - C ko:K04091,ko:K20938 ko00920,map00920 ko00000,ko00001,ko01000 Catalyzes the desulfonation of aliphatic sulfonates
PGHHMJKG_02251 4.62e-187 ssuC - - P ko:K15554 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PGHHMJKG_02252 2.79e-213 ssuA - - M ko:K15553 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko02000 Sulfonate ABC transporter
PGHHMJKG_02253 7.4e-178 ssuB - - P ko:K15555 ko00920,ko02010,map00920,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PGHHMJKG_02254 0.0 katA 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PGHHMJKG_02256 0.0 thiC 4.1.99.17 - H ko:K03147 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PGHHMJKG_02257 5.27e-168 ygaJ 3.4.13.21 - E ko:K05995 - ko00000,ko01000,ko01002 Belongs to the peptidase S51 family
PGHHMJKG_02258 1.58e-36 - - - - - - - -
PGHHMJKG_02259 1.5e-183 spo0M - - S ko:K06377 - ko00000 COG4326 Sporulation control protein
PGHHMJKG_02260 2.84e-240 yfmJ - - S ko:K07119 - ko00000 N-terminal domain of oxidoreductase
PGHHMJKG_02261 1.15e-191 fhuC 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PGHHMJKG_02262 2.98e-223 fecD - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_02263 8.17e-221 - - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_02264 1.94e-219 yfmC - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PGHHMJKG_02265 1.06e-31 - - - S - - - Protein of unknown function (DUF3212)
PGHHMJKG_02266 1.71e-76 yflT - - S - - - Heat induced stress protein YflT
PGHHMJKG_02267 1.16e-305 pel 4.2.2.2 - G ko:K01728 ko00040,ko02024,map00040,map02024 ko00000,ko00001,ko01000 Pectate lyase
PGHHMJKG_02268 0.0 yflS - - P ko:K03319 - ko00000 Sodium:sulfate symporter transmembrane region
PGHHMJKG_02269 0.0 citS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PGHHMJKG_02270 2.68e-152 citT - - T ko:K11638 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 response regulator
PGHHMJKG_02271 1.62e-229 yflP - - S - - - Tripartite tricarboxylate transporter family receptor
PGHHMJKG_02272 5.35e-288 citM - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PGHHMJKG_02273 1.7e-192 yflN - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PGHHMJKG_02274 4.6e-274 nos 1.14.14.47 - C ko:K00491 ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PGHHMJKG_02275 2.97e-59 acyP 3.6.1.7 - C ko:K01512 ko00620,ko00627,ko01120,map00620,map00627,map01120 ko00000,ko00001,ko01000 Belongs to the acylphosphatase family
PGHHMJKG_02276 3.42e-157 yflK - - S - - - protein conserved in bacteria
PGHHMJKG_02277 3.16e-25 yflJ - - S - - - Protein of unknown function (DUF2639)
PGHHMJKG_02278 6.9e-27 yflI - - - - - - -
PGHHMJKG_02279 1.73e-64 yflH - - S - - - Protein of unknown function (DUF3243)
PGHHMJKG_02280 1.14e-178 yflG 3.4.11.18 - E ko:K01265 - ko00000,ko01000,ko01002 Methionine aminopeptidase
PGHHMJKG_02281 0.0 nagE 2.7.1.193, 2.7.1.199 - G ko:K02802,ko:K02803,ko:K02804,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PGHHMJKG_02282 0.0 yflE 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PGHHMJKG_02283 1.89e-87 ydhN1 - - S - - - Domain of unknown function (DUF1992)
PGHHMJKG_02284 1.43e-41 yfkQ - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PGHHMJKG_02285 0.0 treP 2.7.1.201 - G ko:K02818,ko:K02819 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_02286 0.0 treC 3.2.1.93 GH13 G ko:K01226 ko00500,map00500 ko00000,ko00001,ko01000 COG0366 Glycosidases
PGHHMJKG_02287 1.24e-172 treR - - K ko:K03486 - ko00000,ko03000 transcriptional
PGHHMJKG_02288 6.16e-160 frp - - C - - - nitroreductase
PGHHMJKG_02289 0.0 yfkN 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 - F ko:K01081,ko:K01119,ko:K06931,ko:K08693,ko:K11751 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PGHHMJKG_02290 1.83e-112 yfkM 3.5.1.124 - S ko:K05520 - ko00000,ko01000,ko01002 protease
PGHHMJKG_02291 6.93e-263 ydiN3 - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_02292 5.99e-41 yfkK - - S - - - Belongs to the UPF0435 family
PGHHMJKG_02293 5.89e-108 yfkJ 3.1.3.48 - T ko:K01104 - ko00000,ko01000 Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PGHHMJKG_02294 1.03e-66 yfkI - - S - - - gas vesicle protein
PGHHMJKG_02295 9.64e-184 yihY - - S ko:K07058 - ko00000 Belongs to the UPF0761 family
PGHHMJKG_02296 1.9e-278 yfkF - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_02297 5.44e-235 cax - - P ko:K07300 - ko00000,ko02000 COG0387 Ca2 H antiporter
PGHHMJKG_02298 3.69e-189 yfkD - - S - - - YfkD-like protein
PGHHMJKG_02299 4.44e-191 yfkC - - M - - - Mechanosensitive ion channel
PGHHMJKG_02300 1.76e-283 yfkA - - S - - - YfkB-like domain
PGHHMJKG_02301 3.26e-36 yfjT - - - - - - -
PGHHMJKG_02302 5.95e-197 pdaA - - G ko:K01567 - ko00000,ko01000 deacetylase
PGHHMJKG_02303 7.99e-193 yfjR - - I - - - NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PGHHMJKG_02304 1.24e-233 corA - - P ko:K03284 - ko00000,ko02000 Mediates influx of magnesium ions
PGHHMJKG_02305 3.92e-214 yfjP 3.2.2.21 - L ko:K01247 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PGHHMJKG_02306 0.0 rumA_1 2.1.1.190, 2.1.1.35 - J ko:K00557,ko:K03215 - ko00000,ko01000,ko03009,ko03016 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PGHHMJKG_02307 3.04e-59 - - - S - - - YfzA-like protein
PGHHMJKG_02308 1.25e-236 yfjN - - J - - - Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGHHMJKG_02309 7.85e-110 yfjM - - S - - - Psort location Cytoplasmic, score
PGHHMJKG_02311 6.48e-243 acoA - - C ko:K21416 - ko00000,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PGHHMJKG_02312 8.81e-241 acoB - - C ko:K21417 - ko00000,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGHHMJKG_02313 4.19e-265 acoC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGHHMJKG_02314 0.0 acoL 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PGHHMJKG_02315 0.0 acoR - - KQ ko:K21405 - ko00000,ko03000 COG3284 Transcriptional activator of acetoin glycerol metabolism
PGHHMJKG_02316 3.9e-34 sspH - - S ko:K06425 - ko00000 Belongs to the SspH family
PGHHMJKG_02317 2.9e-74 yfjF - - S ko:K09771 - ko00000,ko02000 UPF0060 membrane protein
PGHHMJKG_02318 1e-105 - - - S - - - Family of unknown function (DUF5381)
PGHHMJKG_02319 1.49e-131 yfjD - - S - - - Family of unknown function (DUF5381)
PGHHMJKG_02320 1.02e-184 yfjC - - - - - - -
PGHHMJKG_02321 1.94e-270 yfjB - - - - - - -
PGHHMJKG_02322 5.59e-61 yfjA - - S - - - Belongs to the WXG100 family
PGHHMJKG_02323 0.0 malH 3.2.1.122 GH4 G ko:K01232 ko00500,map00500 ko00000,ko00001,ko01000 COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PGHHMJKG_02324 1.23e-180 - - - K ko:K03481 - ko00000,ko03000 Helix-turn-helix domain, rpiR family
PGHHMJKG_02325 0.0 glvC 2.7.1.208 - G ko:K02749,ko:K02750 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_02326 0.0 yfiB3 - - V ko:K06147 - ko00000,ko02000 ABC transporter
PGHHMJKG_02327 0.0 yfiC3 - - V ko:K06147 - ko00000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PGHHMJKG_02328 1.93e-82 yfiD3 - - S - - - DoxX
PGHHMJKG_02329 2.97e-208 yfiE 1.13.11.2 - S ko:K07104 ko00361,ko00362,ko00622,ko00643,ko01100,ko01120,ko01220,map00361,map00362,map00622,map00643,map01100,map01120,map01220 ko00000,ko00001,ko00002,ko01000 glyoxalase
PGHHMJKG_02331 1.7e-272 baeS - - T - - - Histidine kinase
PGHHMJKG_02332 5.82e-144 yfiK - - KT ko:K02479 - ko00000,ko02022 LuxR family transcriptional regulator
PGHHMJKG_02333 1.78e-213 drrA - - V ko:K01990,ko:K09695 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_02334 5.69e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 ABC-2 family transporter protein
PGHHMJKG_02335 3.44e-262 - - - V ko:K01992 - ko00000,ko00002,ko02000 COG0842 ABC-type multidrug transport system, permease component
PGHHMJKG_02336 1.89e-128 padR - - K - - - transcriptional
PGHHMJKG_02337 7.87e-128 lip 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PGHHMJKG_02338 2.68e-252 yfiQ - - G ko:K21462 - ko00000 COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PGHHMJKG_02339 4.01e-139 yfiR - - K - - - Transcriptional regulator
PGHHMJKG_02340 1.91e-266 yfiS - - EGP - - - Major facilitator superfamily
PGHHMJKG_02341 4.67e-127 yfiT - - S - - - Belongs to the metal hydrolase YfiT family
PGHHMJKG_02342 1.11e-291 yfiU - - EGP - - - the major facilitator superfamily
PGHHMJKG_02343 7.8e-22 yfiU - - EGP - - - the major facilitator superfamily
PGHHMJKG_02344 4.26e-103 yfiV - - K - - - transcriptional
PGHHMJKG_02345 0.0 mprF 2.3.2.3 - S ko:K14205 ko01503,ko02020,ko05150,map01503,map02020,map05150 ko00000,ko00001,ko00002,ko01000,ko01504 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PGHHMJKG_02346 1.28e-229 yfiY - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PGHHMJKG_02347 8.91e-225 yfiZ - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_02348 5.18e-229 yfhA - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_02349 9.95e-211 yfhB - - S - - - PhzF family
PGHHMJKG_02350 1.17e-137 yfhC - - C - - - nitroreductase
PGHHMJKG_02351 8.86e-35 yfhD - - S - - - YfhD-like protein
PGHHMJKG_02353 2.56e-218 yfhF - - S ko:K07071 - ko00000 nucleoside-diphosphate sugar epimerase
PGHHMJKG_02354 2.67e-180 recX - - S ko:K03565 - ko00000,ko03400 Modulates RecA activity
PGHHMJKG_02355 4.58e-69 yfhH - - S - - - Protein of unknown function (DUF1811)
PGHHMJKG_02357 2.45e-268 yfhI - - EGP - - - -transporter
PGHHMJKG_02358 2.25e-27 sspK - - S ko:K06428 - ko00000 reproduction
PGHHMJKG_02359 8.95e-60 yfhJ - - S - - - WVELL protein
PGHHMJKG_02360 7.22e-119 yfhK - - T - - - Bacterial SH3 domain homologues
PGHHMJKG_02361 6.3e-66 yfhL - - S - - - SdpI/YhfL protein family
PGHHMJKG_02362 1.13e-217 yfhM 3.8.1.5 - S ko:K01563 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Alpha beta hydrolase
PGHHMJKG_02363 3.43e-236 csbB - GT2 M ko:K20534 - ko00000,ko01000,ko01005,ko02000 COG0463 Glycosyltransferases involved in cell wall biogenesis
PGHHMJKG_02364 0.0 yfhO - - S - - - Bacterial membrane protein YfhO
PGHHMJKG_02365 2.07e-236 yfhP - - S ko:K07038 - ko00000 membrane-bound metal-dependent
PGHHMJKG_02366 1.99e-266 mutY - - L ko:K03575 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 A G-specific
PGHHMJKG_02367 1.73e-48 yfhS - - - - - - -
PGHHMJKG_02368 3.13e-172 fabL 1.3.1.104 - IQ ko:K10780 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_02369 2.35e-14 sspE - - S ko:K06422 - ko00000 Small, acid-soluble spore protein, gamma-type
PGHHMJKG_02370 1.88e-63 ygaB - - S - - - YgaB-like protein
PGHHMJKG_02371 8.1e-136 ygaC - - J ko:K07586 - ko00000 Belongs to the UPF0374 family
PGHHMJKG_02372 0.0 ygaD - - V ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 ABC transporter
PGHHMJKG_02373 8.86e-237 ygaE - - S - - - Membrane
PGHHMJKG_02374 3.26e-312 gsaB 5.4.3.8 - H ko:K01845 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Glutamate-1-semialdehyde aminotransferase
PGHHMJKG_02375 2.92e-113 bcp 1.11.1.15 - O ko:K03564 - ko00000,ko01000 Peroxiredoxin
PGHHMJKG_02376 2.37e-104 perR - - P ko:K09825 - ko00000,ko03000 Belongs to the Fur family
PGHHMJKG_02377 5.46e-74 ygzB - - S - - - UPF0295 protein
PGHHMJKG_02378 8.23e-215 ygxA - - S - - - Nucleotidyltransferase-like
PGHHMJKG_02379 1.88e-172 adcB - - P ko:K09816 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PGHHMJKG_02380 2.32e-169 adcC - - P ko:K02074,ko:K09817 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PGHHMJKG_02381 1.95e-221 adcA - - P ko:K09815 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 9 family
PGHHMJKG_02382 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G ko:K01182,ko:K01187 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 COG0366 Glycosidases
PGHHMJKG_02383 7.67e-177 - 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 Enoyl-(Acyl carrier protein) reductase
PGHHMJKG_02384 1.65e-247 rapJ - - S ko:K06368 - ko00000,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_02385 1.53e-122 - - - M ko:K17733 - ko00000,ko01000,ko01002,ko01011 D-alanyl-D-alanine carboxypeptidase
PGHHMJKG_02386 0.0 ycdC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_02387 0.0 ycdB - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_02388 6.38e-229 ycdA - - S - - - Domain of unknown function (DUF5105)
PGHHMJKG_02390 6.56e-107 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGHHMJKG_02391 1.07e-81 yceB - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGHHMJKG_02392 2.53e-139 yceC 3.5.4.33 - T ko:K11991 - ko00000,ko01000,ko03016 proteins involved in stress response, homologs of TerZ and
PGHHMJKG_02393 8.9e-137 yceD - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PGHHMJKG_02394 4.97e-138 yceE - - T ko:K05795 - ko00000 proteins involved in stress response, homologs of TerZ and
PGHHMJKG_02395 1.18e-175 yceF - - P ko:K05794 - ko00000 Protein of unknown function (DUF475)
PGHHMJKG_02396 0.0 yceG - - S - - - Putative component of 'biosynthetic module'
PGHHMJKG_02397 2.96e-245 yceH - - P - - - Belongs to the TelA family
PGHHMJKG_02398 2.59e-276 yceI - - P ko:K08369 - ko00000,ko02000 Uncharacterised MFS-type transporter YbfB
PGHHMJKG_02399 1.72e-255 - - - EGP - - - Uncharacterised MFS-type transporter YbfB
PGHHMJKG_02400 8.04e-181 - 2.8.1.7 - E ko:K04487 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000,ko02048,ko03016,ko03029 Aminotransferase class-V
PGHHMJKG_02401 1.9e-41 - - - S - - - DNA sulphur modification protein DndE
PGHHMJKG_02402 3.14e-187 - - - EL ko:K19171 - ko00000,ko02048 AAA domain
PGHHMJKG_02403 8.5e-272 - - - EH ko:K19170 - ko00000,ko02048 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
PGHHMJKG_02404 2.86e-193 - - - S ko:K19169 - ko00000,ko02048 DNA-sulfur modification-associated
PGHHMJKG_02405 3.83e-131 - - - V ko:K19173 - ko00000,ko02048 Type I site-specific restriction-modification system, R (Restriction) subunit and related
PGHHMJKG_02406 2.19e-86 - - - - ko:K19174 - ko00000,ko02048 -
PGHHMJKG_02407 0.0 - - - S ko:K19175 - ko00000,ko02048 Domain of unknown function DUF87
PGHHMJKG_02408 4.82e-61 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PGHHMJKG_02409 8.99e-293 opuAA 3.6.3.32 - E ko:K02000 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 glycine betaine
PGHHMJKG_02410 2.1e-186 opuAB - - P ko:K02001 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PGHHMJKG_02411 4.73e-209 opuAC - - E ko:K02001,ko:K02002 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 glycine betaine
PGHHMJKG_02412 4.44e-273 amhX - - S ko:K14665 - ko00000,ko01000,ko01002 amidohydrolase
PGHHMJKG_02413 0.0 ycgA - - S - - - Membrane
PGHHMJKG_02414 2.72e-105 ycgB - - - - - - -
PGHHMJKG_02415 0.0 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
PGHHMJKG_02416 1.31e-121 amyE 3.2.1.1 GH13 G ko:K01176 ko00500,ko01100,ko04973,map00500,map01100,map04973 ko00000,ko00001,ko01000 alpha-amylase
PGHHMJKG_02417 2.93e-233 ldh 1.1.1.27 - C ko:K00016 ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922 ko00000,ko00001,ko01000,ko04147 Belongs to the LDH MDH superfamily. LDH family
PGHHMJKG_02418 0.0 lctP - - C ko:K03303 - ko00000,ko02000 L-lactate permease
PGHHMJKG_02419 3.07e-194 yqcI - - S ko:K09190 - ko00000 YqcI/YcgG family
PGHHMJKG_02420 4.4e-134 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_02421 2.67e-154 ycgH - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_02422 7.6e-145 ycgI - - S ko:K09967 - ko00000 Domain of unknown function (DUF1989)
PGHHMJKG_02423 1.83e-191 nadE 6.3.1.5 - H ko:K01916 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PGHHMJKG_02424 1.31e-140 tmrB - - S - - - AAA domain
PGHHMJKG_02425 1.05e-136 aroK 2.7.1.71 - F ko:K00891 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PGHHMJKG_02426 1.29e-186 - - - Q - - - ubiE/COQ5 methyltransferase family
PGHHMJKG_02427 5.64e-228 ycgK - - K ko:K04761 ko02026,map02026 ko00000,ko00001,ko03000 LysR substrate binding domain
PGHHMJKG_02428 1.1e-231 cah 3.1.1.41 - Q ko:K01060 ko00311,ko01130,map00311,map01130 ko00000,ko00001,ko01000 Acetyl xylan esterase (AXE1)
PGHHMJKG_02429 3.69e-185 ycgL - - S ko:K07074 - ko00000 Predicted nucleotidyltransferase
PGHHMJKG_02430 3.63e-218 ycgM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PGHHMJKG_02431 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PGHHMJKG_02432 0.0 putP - - E ko:K11928 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGHHMJKG_02433 3.92e-288 ycgP - - QT - - - COG2508 Regulator of polyketide synthase expression
PGHHMJKG_02434 3.82e-195 ycgQ - - S ko:K08986 - ko00000 membrane
PGHHMJKG_02435 3.19e-187 ycgR - - S ko:K07089 - ko00000 permeases
PGHHMJKG_02436 3.3e-200 ycgS - - I - - - alpha/beta hydrolase fold
PGHHMJKG_02437 8.53e-245 ycgT 1.18.1.2, 1.19.1.1 - C ko:K21567 - ko00000,ko01000 Ferredoxin--NADP reductase
PGHHMJKG_02438 0.0 nasF 2.1.1.107, 4.2.1.75 - H ko:K13542 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the precorrin methyltransferase family
PGHHMJKG_02439 1.2e-74 nasE 1.7.1.15 - P ko:K00363 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Nitrite reductase
PGHHMJKG_02440 0.0 nasD 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PGHHMJKG_02441 0.0 nasC - - C ko:K00372 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PGHHMJKG_02442 0.0 nasB 1.7.1.15 - C ko:K00362 ko00910,ko01120,map00910,map01120 ko00000,ko00001,ko00002,ko01000 Assimilatory nitrate reductase (electron transfer subunit)
PGHHMJKG_02443 5.51e-283 nasA - - P ko:K02575 ko00910,map00910 ko00000,ko00001,ko00002,ko02000 COG2223 Nitrate nitrite transporter
PGHHMJKG_02444 2.21e-150 folE2 3.5.4.16 - S ko:K09007 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Converts GTP to 7,8-dihydroneopterin triphosphate
PGHHMJKG_02445 2.12e-87 - - - M - - - ErfK YbiS YcfS YnhG
PGHHMJKG_02446 2.72e-141 yciC - - S - - - GTPases (G3E family)
PGHHMJKG_02447 2.26e-123 yciC - - S - - - GTPases (G3E family)
PGHHMJKG_02448 3.35e-146 yckA - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PGHHMJKG_02449 1.03e-184 yckB - - ET ko:K02030,ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PGHHMJKG_02452 1.11e-96 yckC - - S - - - membrane
PGHHMJKG_02453 1.38e-66 yckD - - S - - - Protein of unknown function (DUF2680)
PGHHMJKG_02454 1.06e-57 - - - K - - - MarR family
PGHHMJKG_02455 2.49e-27 - - - - - - - -
PGHHMJKG_02456 2.13e-113 - - - S - - - AAA domain
PGHHMJKG_02457 8.9e-22 - - - S - - - AAA domain
PGHHMJKG_02458 0.0 yckE 3.2.1.21, 3.2.1.86 GT1 G ko:K01223,ko:K05350 ko00010,ko00460,ko00500,ko00940,ko01100,ko01110,map00010,map00460,map00500,map00940,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGHHMJKG_02459 3.36e-91 nin - - S - - - Competence protein J (ComJ)
PGHHMJKG_02460 7.94e-100 nucA - - M - - - Deoxyribonuclease NucA/NucB
PGHHMJKG_02461 3.11e-73 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_02462 9.46e-163 tlpC - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_02463 3.24e-126 hxlB 5.3.1.27 - G ko:K08094 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 SIS domain
PGHHMJKG_02464 5.63e-137 hxlA 4.1.2.43 - G ko:K08093 ko00030,ko00680,ko01100,ko01120,ko01200,ko01230,map00030,map00680,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 3-hexulose-6-phosphate synthase
PGHHMJKG_02465 5.93e-85 hxlR - - K - - - transcriptional
PGHHMJKG_02468 3.5e-269 glcP - - G ko:K08174 - ko00000,ko02000 Major Facilitator Superfamily
PGHHMJKG_02469 9.38e-256 - 1.1.1.18, 1.1.1.361, 1.1.1.369 - S ko:K00010,ko:K18652 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PGHHMJKG_02470 8.81e-204 ntdB 3.1.3.24, 3.1.3.92 - S ko:K07024,ko:K18654 ko00500,map00500 ko00000,ko00001,ko01000 Sucrose-6F-phosphate phosphohydrolase
PGHHMJKG_02471 0.0 - 2.6.1.104 - E ko:K18653 - ko00000,ko01000 Belongs to the DegT DnrJ EryC1 family
PGHHMJKG_02472 5.09e-238 yhjM - - K - - - Transcriptional regulator
PGHHMJKG_02473 5.04e-259 yhjN - - S ko:K07120 - ko00000 membrane
PGHHMJKG_02474 1.36e-267 - - - EGP - - - Transmembrane secretion effector
PGHHMJKG_02475 0.0 - - - S - - - Sugar transport-related sRNA regulator N-term
PGHHMJKG_02476 6.29e-100 yhjR - - S - - - Rubrerythrin
PGHHMJKG_02477 0.0 rexB 3.6.4.12 - L ko:K16899 - ko00000,ko01000,ko03400 ATP-dependent helicase deoxyribonuclease subunit B
PGHHMJKG_02478 0.0 addA 3.6.4.12 - L ko:K16898 - ko00000,ko01000,ko03400 ATP-dependent helicase nuclease subunit A
PGHHMJKG_02479 3.84e-278 sbcD - - L ko:K03547 - ko00000,ko03400 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PGHHMJKG_02480 0.0 sbcC - - L ko:K03546 - ko00000,ko03400 COG0419 ATPase involved in DNA repair
PGHHMJKG_02481 7.78e-66 yisB - - V - - - COG1403 Restriction endonuclease
PGHHMJKG_02482 3.3e-43 gerPF - - S ko:K06299,ko:K06304 - ko00000 Spore germination protein gerPA/gerPF
PGHHMJKG_02483 4.08e-88 gerPE - - S ko:K06303 - ko00000 Spore germination protein GerPE
PGHHMJKG_02484 1.49e-33 gerPD - - S ko:K06302 - ko00000 Spore germination protein
PGHHMJKG_02485 1e-93 gerPC - - S ko:K06301 - ko00000 Spore germination protein
PGHHMJKG_02486 1.02e-46 gerPB - - S ko:K06300 - ko00000 cell differentiation
PGHHMJKG_02487 7.41e-45 gerPA - - S ko:K06299 - ko00000 Spore germination protein
PGHHMJKG_02488 1.52e-32 yisI - - S - - - Spo0E like sporulation regulatory protein
PGHHMJKG_02489 1.88e-222 cotH - - M ko:K06330 - ko00000 Spore Coat
PGHHMJKG_02490 3.11e-218 yisK - - Q - - - COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PGHHMJKG_02491 1.02e-74 yisL - - S - - - UPF0344 protein
PGHHMJKG_02492 0.0 wprA - - O ko:K13274 - ko00000,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PGHHMJKG_02493 3.3e-234 uvsE - - L ko:K13281 - ko00000,ko01000 Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PGHHMJKG_02494 1.82e-275 clsB - - I ko:K06131 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PGHHMJKG_02495 0.0 ywjF - - C - - - COG0247 Fe-S oxidoreductase
PGHHMJKG_02496 5.77e-267 acdA - - I - - - acyl-CoA dehydrogenase
PGHHMJKG_02497 3.27e-80 rpoE - - K ko:K03048 ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020 br01611,ko00000,ko00001,ko00002,ko03021,ko03400 Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PGHHMJKG_02498 0.0 pyrG 6.3.4.2 - F ko:K01937 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PGHHMJKG_02499 1.88e-254 - - - L - - - COG3666 Transposase and inactivated derivatives
PGHHMJKG_02501 4.78e-152 - - - L - - - Bacterial dnaA protein
PGHHMJKG_02502 6.98e-279 - - - L - - - Transposase
PGHHMJKG_02504 9.99e-48 ydjO - - S - - - Cold-inducible protein YdjO
PGHHMJKG_02505 1.46e-201 - - - I - - - Alpha/beta hydrolase family
PGHHMJKG_02506 6.33e-103 yeaA - - S - - - Protein of unknown function (DUF4003)
PGHHMJKG_02507 0.0 cotA 1.16.3.3 - Q ko:K06324 - ko00000,ko01000 multicopper oxidases
PGHHMJKG_02508 0.0 gabP - - E ko:K11735 - ko00000,ko02000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_02509 1.76e-198 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGHHMJKG_02510 5.62e-226 yeaC - - S ko:K03924 - ko00000,ko01000 COG0714 MoxR-like ATPases
PGHHMJKG_02511 1.07e-283 yeaD - - S - - - conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PGHHMJKG_02512 0.0 yebA - - E - - - COG1305 Transglutaminase-like enzymes
PGHHMJKG_02513 0.0 guaA 6.3.5.2 - F ko:K01951 ko00230,ko00983,ko01100,map00230,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the synthesis of GMP from XMP
PGHHMJKG_02514 6.3e-111 - - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_02515 1.15e-314 - - - S - - - Domain of unknown function (DUF4179)
PGHHMJKG_02516 6.6e-281 pbuG - - S ko:K06901 - ko00000,ko02000 permease
PGHHMJKG_02517 5.85e-165 yebC - - M - - - Membrane
PGHHMJKG_02518 4.34e-157 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGHHMJKG_02519 1.05e-40 csrA - - T ko:K03563 ko02020,ko02025,ko02026,ko05111,map02020,map02025,map02026,map05111 ko00000,ko00001,ko03019 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PGHHMJKG_02520 1.23e-96 fliW - - S ko:K13626 - ko00000,ko02035 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PGHHMJKG_02521 6.92e-92 yviE - - - - - - -
PGHHMJKG_02522 7.66e-197 flgL - - N ko:K02397 ko02040,map02040 ko00000,ko00001,ko02035 Belongs to the bacterial flagellin family
PGHHMJKG_02523 0.0 flgK - - N ko:K02396 ko02040,map02040 ko00000,ko00001,ko02035 flagellar hook-associated protein
PGHHMJKG_02524 7.06e-102 yvyG - - NOU - - - FlgN protein
PGHHMJKG_02525 8.72e-53 flgM - - KNU ko:K02398 ko02020,ko02025,ko02026,ko02040,map02020,map02025,map02026,map02040 ko00000,ko00001,ko02035 Negative regulator of flagellin synthesis
PGHHMJKG_02526 1.06e-95 yvyF - - S - - - flagellar protein
PGHHMJKG_02527 2.26e-162 comFC - - S ko:K02242 - ko00000,ko00002,ko02044 Phosphoribosyl transferase domain
PGHHMJKG_02528 1.26e-61 comFB - - S ko:K02241 - ko00000,ko00002,ko02044 Late competence development protein ComFB
PGHHMJKG_02529 0.0 comFA - - L ko:K02240 - ko00000,ko00002,ko02044 COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PGHHMJKG_02530 1.24e-198 degV - - S - - - protein conserved in bacteria
PGHHMJKG_02531 2.92e-162 degU - - KT ko:K02479,ko:K07692 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_02532 2.94e-247 degS 2.7.13.3 - T ko:K07777 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PGHHMJKG_02533 1.94e-136 yvyE 3.4.13.9 - S ko:K01271 - ko00000,ko01000,ko01002 Domain of unknown function (DUF1949)
PGHHMJKG_02534 1.23e-151 - - - K - - - Transcriptional regulator
PGHHMJKG_02538 1.03e-50 - - - S - - - Psort location CytoplasmicMembrane, score
PGHHMJKG_02541 4.26e-100 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_02543 2.99e-231 tagO 2.7.8.33, 2.7.8.35 - M ko:K02851 - ko00000,ko01000,ko01003,ko01005 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PGHHMJKG_02544 7.15e-298 tuaH - - M ko:K16699 - ko00000,ko01000,ko01003 Teichuronic acid biosynthesis glycosyltransferase tuaH
PGHHMJKG_02545 1.33e-174 tuaG - GT2 M ko:K16698 - ko00000,ko01000,ko01003 Glycosyltransferase like family 2
PGHHMJKG_02546 4.16e-137 tuaF - - M ko:K16706 - ko00000 protein involved in exopolysaccharide biosynthesis
PGHHMJKG_02547 4.47e-315 tuaE - - M ko:K16705 - ko00000 Teichuronic acid biosynthesis protein
PGHHMJKG_02549 1.16e-301 tuaD 1.1.1.22 - M ko:K00012 ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PGHHMJKG_02550 4.98e-256 tuaC - GT4 GM ko:K16697 - ko00000,ko01000,ko01003 Teichuronic acid
PGHHMJKG_02551 1.82e-300 tuaB - - S ko:K03328,ko:K16694,ko:K16695 - ko00000,ko02000 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PGHHMJKG_02552 2.13e-150 tuaA - - M - - - COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PGHHMJKG_02553 1.07e-57 hbs - - L ko:K03530 - ko00000,ko03032,ko03036,ko03400 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PGHHMJKG_02554 0.0 spoIVA - - S ko:K06398 - ko00000 ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PGHHMJKG_02555 8.71e-176 yphF - - - - - - -
PGHHMJKG_02556 1.43e-26 yphE - - S - - - Protein of unknown function (DUF2768)
PGHHMJKG_02557 2.01e-243 gpsA 1.1.1.94 - I ko:K00057 ko00564,ko01110,map00564,map01110 ko00000,ko00001,ko01000 Glycerol-3-phosphate dehydrogenase
PGHHMJKG_02558 5.72e-316 der - - S ko:K03977 - ko00000,ko03009 GTPase that plays an essential role in the late steps of ribosome biogenesis
PGHHMJKG_02559 2.06e-38 ypzH - - - - - - -
PGHHMJKG_02560 4.35e-207 yphB - - S ko:K05739 - ko00000 YIEGIA protein
PGHHMJKG_02561 1.11e-133 yphA - - - - - - -
PGHHMJKG_02562 1.13e-11 - - - S - - - YpzI-like protein
PGHHMJKG_02563 2.34e-97 ylbF - - S - - - Belongs to the UPF0342 family
PGHHMJKG_02564 4.36e-52 ylbG - - S - - - UPF0298 protein
PGHHMJKG_02565 1.43e-124 rsmD 2.1.1.171 - L ko:K08316 - ko00000,ko01000,ko03009 Methyltransferase
PGHHMJKG_02566 3.8e-111 coaD 2.7.7.3 - H ko:K00954 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PGHHMJKG_02567 9.11e-281 ylbJ - - S - - - Sporulation integral membrane protein YlbJ
PGHHMJKG_02568 2.56e-176 ylbK - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PGHHMJKG_02569 7.81e-239 ylbL - - T ko:K07177 ko02024,map02024 ko00000,ko00001,ko01002 Belongs to the peptidase S16 family
PGHHMJKG_02570 1.67e-291 ylbM - - S - - - Belongs to the UPF0348 family
PGHHMJKG_02572 1.15e-115 ylbN - - S ko:K07040 - ko00000 metal-binding, possibly nucleic acid-binding protein
PGHHMJKG_02573 1.71e-37 rpmF - - J ko:K02911 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011,ko03029 Belongs to the bacterial ribosomal protein bL32 family
PGHHMJKG_02574 1.35e-106 ylbO - - S ko:K06314 - ko00000,ko03000 SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PGHHMJKG_02575 1.33e-115 ylbP - - K - - - n-acetyltransferase
PGHHMJKG_02576 3.22e-214 panE 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGHHMJKG_02577 0.0 bshC - - S ko:K22136 - ko00000 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PGHHMJKG_02578 9.82e-102 mraZ - - K ko:K03925 - ko00000 Belongs to the MraZ family
PGHHMJKG_02579 1.66e-218 rsmH 2.1.1.199 - J ko:K03438 - ko00000,ko01000,ko03009 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PGHHMJKG_02580 3.42e-68 ftsL - - D - - - Essential cell division protein
PGHHMJKG_02581 0.0 pbpX - - M ko:K08724,ko:K12552,ko:K12556 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PGHHMJKG_02582 0.0 spoVD - - M ko:K08384 ko00550,map00550 ko00000,ko00001,ko01011 stage V sporulation protein D
PGHHMJKG_02583 0.0 murE 6.3.2.13 - M ko:K01928 ko00300,ko00550,map00300,map00550 ko00000,ko00001,ko01000,ko01011 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PGHHMJKG_02584 9.59e-220 mraY 2.7.8.13 - M ko:K01000 ko00550,ko01100,ko01502,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PGHHMJKG_02585 0.0 murD 6.3.2.9 - M ko:K01925 ko00471,ko00550,ko01100,map00471,map00550,map01100 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PGHHMJKG_02586 6.64e-237 spoVE - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PGHHMJKG_02587 3.15e-256 murG 2.4.1.227 GT28 M ko:K02563 ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112 ko00000,ko00001,ko01000,ko01011 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PGHHMJKG_02588 1.3e-211 murB 1.3.1.98 - M ko:K00075 ko00520,ko00550,ko01100,map00520,map00550,map01100 ko00000,ko00001,ko01000,ko01011 cell wall formation
PGHHMJKG_02589 2.77e-177 divIB - - D ko:K03589 ko04112,map04112 ko00000,ko00001,ko03036 Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PGHHMJKG_02590 1.35e-143 ylxW - - S - - - protein conserved in bacteria
PGHHMJKG_02591 8.67e-132 ylxX - - S - - - protein conserved in bacteria
PGHHMJKG_02592 5.37e-76 sbp - - S - - - small basic protein
PGHHMJKG_02593 4.88e-299 ftsA - - D ko:K03590 ko04112,map04112 ko00000,ko00001,ko03036,ko04812 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PGHHMJKG_02594 1.84e-260 ftsZ - - D ko:K03531 ko04112,map04112 ko00000,ko00001,ko02048,ko03036,ko04812 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PGHHMJKG_02595 0.0 bpr - - O ko:K13276 - ko00000,ko01000,ko01002,ko03110 COG1404 Subtilisin-like serine proteases
PGHHMJKG_02597 3.49e-219 spoIIGA - - M ko:K06383 - ko00000,ko01000,ko01002 aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PGHHMJKG_02598 1.48e-160 sigE - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_02599 6.57e-179 sigG - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_02600 6.37e-188 ylmA 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PGHHMJKG_02601 0.0 argE - - E ko:K20895 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Acetylornithine deacetylase
PGHHMJKG_02602 3.58e-51 ylmC - - S - - - sporulation protein
PGHHMJKG_02603 7.53e-203 ylmD - - S ko:K05810 - ko00000,ko01000 Belongs to the multicopper oxidase YfiH RL5 family
PGHHMJKG_02604 3.15e-162 ylmE - - S ko:K06997 - ko00000 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PGHHMJKG_02605 5.44e-88 sepF - - D ko:K09772 - ko00000,ko03036 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PGHHMJKG_02606 1.74e-53 ylmG - - S ko:K02221 - ko00000,ko02044 membrane
PGHHMJKG_02607 2.03e-176 ylmH - - S - - - conserved protein, contains S4-like domain
PGHHMJKG_02608 6.44e-100 divIVA - - D ko:K04074 - ko00000,ko03036 Cell division initiation protein
PGHHMJKG_02609 0.0 ileS 6.1.1.5 - J ko:K01870 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PGHHMJKG_02610 1.39e-37 - - - L - - - DnaD domain protein
PGHHMJKG_02612 0.000533 - - - K ko:K07075,ko:K15773 - ko00000,ko02048,ko03000 sequence-specific DNA binding
PGHHMJKG_02613 1.47e-67 ypuA - - S - - - Protein of unknown function (DUF1002)
PGHHMJKG_02624 2.17e-10 - - - - - - - -
PGHHMJKG_02625 4.66e-68 yhcS 3.4.22.70 - M ko:K07284 - ko00000,ko01000,ko01002,ko01011 COG3764 Sortase (surface protein transpeptidase)
PGHHMJKG_02626 1.7e-177 - - - M - - - Psort location Cellwall, score
PGHHMJKG_02633 4.77e-16 - - - S - - - YolD-like protein
PGHHMJKG_02635 1.48e-34 - - - - - - - -
PGHHMJKG_02636 2.37e-47 - - - L ko:K03630 - ko00000 RadC-like JAB domain
PGHHMJKG_02638 8.48e-171 - - - S ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_02642 4.71e-55 - - - L ko:K07491 - ko00000 Transposase IS200 like
PGHHMJKG_02643 4.25e-273 gltP - - C ko:K11102 - ko00000,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGHHMJKG_02644 0.0 ptsG 2.7.1.199 - G ko:K02763,ko:K02764,ko:K02765,ko:K20116,ko:K20117,ko:K20118 ko00010,ko00520,ko02060,map00010,map00520,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_02645 4.29e-174 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PGHHMJKG_02646 2.91e-165 - - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PGHHMJKG_02648 1.25e-258 ilvE 2.6.1.42 - E ko:K00826 ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Branched-chain amino acid aminotransferase
PGHHMJKG_02649 0.0 ybgF - - E ko:K02205,ko:K03293,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PGHHMJKG_02650 1.83e-233 mmuM 2.1.1.10 - H ko:K00547 ko00270,ko01100,ko01110,map00270,map01100,map01110 ko00000,ko00001,ko01000 homocysteine
PGHHMJKG_02651 2.77e-37 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PGHHMJKG_02652 2.97e-270 agcS - - E ko:K03310,ko:K11626 ko02020,map02020 ko00000,ko00001 Sodium alanine symporter
PGHHMJKG_02653 4.35e-238 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PGHHMJKG_02654 5.88e-293 glnJ 2.7.13.3 - T ko:K07717 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_02655 5.76e-216 glnL - - T ko:K07719 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Regulator
PGHHMJKG_02656 4.1e-222 ycbC 4.2.1.41 - EM ko:K01707 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 5-dehydro-4-deoxyglucarate dehydratase activity
PGHHMJKG_02657 0.0 ycbD - - C ko:K22187 ko00040,map00040 ko00000,ko00001,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGHHMJKG_02658 0.0 gudP - - G ko:K03535,ko:K08191 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_02659 0.0 gudD 4.2.1.40 - M ko:K01706 ko00053,ko01100,map00053,map01100 ko00000,ko00001,ko01000 Belongs to the mandelate racemase muconate lactonizing enzyme family
PGHHMJKG_02660 7.68e-160 ycbG - - K ko:K05799 - ko00000,ko03000 FCD
PGHHMJKG_02661 0.0 garD 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PGHHMJKG_02662 3.51e-222 ycbJ - - S ko:K06979 - br01600,ko00000,ko00002,ko01504 Macrolide 2'-phosphotransferase
PGHHMJKG_02663 8.73e-33 rtpA - - K - - - Tryptophan RNA-binding attenuator protein inhibitory protein
PGHHMJKG_02664 2.85e-215 eamA1 - - EG - - - spore germination
PGHHMJKG_02665 5.28e-160 ycbL - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_02666 4.37e-214 ycbM - - T - - - Histidine kinase
PGHHMJKG_02667 5.55e-215 - - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_02668 1.73e-149 - - - S - - - ABC-2 family transporter protein
PGHHMJKG_02669 1.82e-75 ycbP - - S - - - Protein of unknown function (DUF2512)
PGHHMJKG_02670 1.82e-102 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
PGHHMJKG_02671 2.63e-11 - - - - - - - -
PGHHMJKG_02672 1e-89 - - - S - - - Phage terminase, small subunit
PGHHMJKG_02673 1.6e-276 - - - S - - - Phage Terminase
PGHHMJKG_02674 2.58e-14 - - - - - - - -
PGHHMJKG_02675 4.77e-273 - - - S - - - Phage portal protein
PGHHMJKG_02676 9.36e-135 - - - S - - - peptidase activity
PGHHMJKG_02677 3.43e-227 - - - S - - - capsid protein
PGHHMJKG_02678 8.02e-09 - - - S - - - peptidoglycan catabolic process
PGHHMJKG_02679 1.23e-39 - - - S - - - peptidoglycan catabolic process
PGHHMJKG_02680 1.23e-32 - - - S - - - Phage gp6-like head-tail connector protein
PGHHMJKG_02681 1.54e-62 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PGHHMJKG_02682 1.42e-40 - - - - - - - -
PGHHMJKG_02683 9.75e-79 - - - - - - - -
PGHHMJKG_02684 1.58e-36 - - - - - - - -
PGHHMJKG_02685 4.09e-16 - - - - - - - -
PGHHMJKG_02686 0.0 - - - S - - - peptidoglycan catabolic process
PGHHMJKG_02687 1.96e-141 - - - S - - - Phage tail protein
PGHHMJKG_02688 1.62e-307 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
PGHHMJKG_02689 3.01e-225 argF 2.1.3.3 - E ko:K00611 ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PGHHMJKG_02690 0.0 carB 6.3.5.5 - EF ko:K01955 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase ammonia chain
PGHHMJKG_02691 3.3e-262 carA 6.3.5.5 - F ko:K01956 ko00240,ko00250,ko01100,map00240,map00250,map01100 ko00000,ko00001,ko00002,ko01000 Carbamoyl-phosphate synthetase glutamine chain
PGHHMJKG_02692 1.14e-276 argD 2.6.1.11, 2.6.1.17 - E ko:K00821 ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 acetylornithine aminotransferase
PGHHMJKG_02693 1.81e-175 argB 2.7.2.8 - E ko:K00930 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the acetylglutamate kinase family. ArgB subfamily
PGHHMJKG_02694 1.37e-290 argJ 2.3.1.1, 2.3.1.35 - E ko:K00620 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PGHHMJKG_02695 3.52e-253 argC 1.2.1.38 - E ko:K00145 ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PGHHMJKG_02696 1.68e-37 yitZ - - G - - - Major Facilitator Superfamily
PGHHMJKG_02697 5.71e-69 yitZ - - G - - - Major Facilitator Superfamily
PGHHMJKG_02698 0.0 yitY - - C - - - D-arabinono-1,4-lactone oxidase
PGHHMJKG_02699 1.74e-31 - - - S - - - Proteolipid membrane potential modulator
PGHHMJKG_02700 4.63e-68 yitW - - S - - - metal-sulfur cluster biosynthetic enzyme
PGHHMJKG_02701 1.19e-183 yitV - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PGHHMJKG_02702 6.18e-198 yitU 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PGHHMJKG_02703 1.92e-08 - - - - - - - -
PGHHMJKG_02704 7.41e-37 - - - S - - - Protein of unknown function (DUF3813)
PGHHMJKG_02705 9.69e-94 ipi - - S - - - Intracellular proteinase inhibitor
PGHHMJKG_02706 2.29e-189 yitT - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PGHHMJKG_02707 4.16e-198 yitS - - S - - - protein conserved in bacteria
PGHHMJKG_02708 0.0 nprB 3.4.24.28 - E ko:K01400,ko:K08777 ko02024,map02024 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PGHHMJKG_02709 4.59e-59 yitR - - S - - - Domain of unknown function (DUF3784)
PGHHMJKG_02710 2.9e-118 - - - - - - - -
PGHHMJKG_02711 8.46e-77 - - - K - - - Transcriptional regulator PadR-like family
PGHHMJKG_02712 3.29e-127 - - - S - - - Sporulation delaying protein SdpA
PGHHMJKG_02713 1.42e-218 - - - - - - - -
PGHHMJKG_02714 2.41e-121 - - - - - - - -
PGHHMJKG_02715 3.91e-204 yitL - - S ko:K00243 - ko00000 protein conserved in bacteria
PGHHMJKG_02716 1.75e-76 yitK - - S ko:K09767 - ko00000 Belongs to the UPF0234 family
PGHHMJKG_02717 0.0 yitJ 1.5.1.20, 2.1.1.10 - E ko:K00297,ko:K00547 ko00270,ko00670,ko00720,ko01100,ko01110,ko01120,ko01200,ko01523,map00270,map00670,map00720,map01100,map01110,map01120,map01200,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PGHHMJKG_02718 2.95e-91 - - - S - - - Acetyltransferase (GNAT) domain
PGHHMJKG_02719 1.77e-96 yitH - - K - - - Acetyltransferase (GNAT) domain
PGHHMJKG_02720 1.52e-197 yisY 1.11.1.10 - I ko:K00433 - ko00000,ko01000 hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PGHHMJKG_02721 2.15e-96 yisX - - S - - - Pentapeptide repeats (9 copies)
PGHHMJKG_02722 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGHHMJKG_02723 5.19e-138 argO - - S ko:K06895 - ko00000,ko02000 Lysine exporter protein LysE YggA
PGHHMJKG_02724 9.94e-120 yisT - - S - - - DinB family
PGHHMJKG_02725 5.32e-242 yisS 1.1.1.18, 1.1.1.369, 1.1.1.370 - S ko:K00010,ko:K16043 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Oxidoreductase family, C-terminal alpha/beta domain
PGHHMJKG_02726 8.71e-234 rbsR - - K ko:K02529,ko:K03484 - ko00000,ko03000 helix_turn _helix lactose operon repressor
PGHHMJKG_02727 1.41e-207 yisR - - K - - - Transcriptional regulator
PGHHMJKG_02728 1.01e-310 yisQ - - V - - - Mate efflux family protein
PGHHMJKG_02729 3.44e-142 crtM 2.5.1.32, 2.5.1.99 - I ko:K02291 ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko01006 phytoene
PGHHMJKG_02730 0.0 asnO 6.3.5.4 - E ko:K01953 ko00250,ko01100,ko01110,map00250,map01100,map01110 ko00000,ko00001,ko01000,ko01002 Asparagine synthase
PGHHMJKG_02731 6.1e-131 yisN - - S - - - Protein of unknown function (DUF2777)
PGHHMJKG_02732 2.51e-39 yjzC - - S - - - YjzC-like protein
PGHHMJKG_02733 2.17e-23 yjzD - - S - - - Protein of unknown function (DUF2929)
PGHHMJKG_02734 5.69e-181 yjaU - - I - - - carboxylic ester hydrolase activity
PGHHMJKG_02735 5.2e-132 yjaV - - - - - - -
PGHHMJKG_02736 5.26e-234 med - - S ko:K05519,ko:K07335 - ko00000,ko03000 Transcriptional activator protein med
PGHHMJKG_02737 8.86e-35 comZ - - S ko:K02254 - ko00000,ko02044 ComZ
PGHHMJKG_02738 2.67e-38 yjzB - - - - - - -
PGHHMJKG_02739 1.61e-221 fabH 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGHHMJKG_02740 3.06e-302 fabF 2.3.1.179 - I ko:K09458 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PGHHMJKG_02741 9.48e-193 yjaZ - - O - - - Zn-dependent protease
PGHHMJKG_02742 6.15e-234 appD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_02743 2.82e-235 appF - - E ko:K02032,ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_02744 0.0 appA - - E ko:K02035 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0747 ABC-type dipeptide transport system, periplasmic component
PGHHMJKG_02745 1.04e-219 appB - - P ko:K02033 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGHHMJKG_02746 8.44e-208 appC - - EP ko:K02034 ko02024,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGHHMJKG_02747 3.18e-190 yjbA - - S - - - Belongs to the UPF0736 family
PGHHMJKG_02748 6.15e-235 trpS 6.1.1.2 - J ko:K01867 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Tryptophanyl-tRNA synthetase
PGHHMJKG_02749 0.0 oppA - - E ko:K15580 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 ABC transporter substrate-binding protein
PGHHMJKG_02750 3.44e-211 oppB - - P ko:K15581 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGHHMJKG_02751 7.55e-212 oppC - - EP ko:K15582,ko:K16201 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PGHHMJKG_02752 3.92e-249 oppD - - P ko:K02031,ko:K15583,ko:K16202 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_02753 4.43e-220 oppF - - E ko:K10823 ko01501,ko02010,ko02024,map01501,map02010,map02024 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_02754 1.18e-267 yjbB - - EGP - - - Major Facilitator Superfamily
PGHHMJKG_02755 2.77e-54 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_02756 1.41e-63 yjbC - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_02757 1.01e-87 spxA - - K ko:K16509 - ko00000 Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PGHHMJKG_02758 4.1e-143 yjbE - - P - - - Integral membrane protein TerC family
PGHHMJKG_02759 3.98e-150 mecA - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PGHHMJKG_02760 9.9e-279 coiA - - S ko:K06198 - ko00000 Competence protein
PGHHMJKG_02761 0.0 pepF - - E ko:K08602 - ko00000,ko01000,ko01002 oligoendopeptidase F
PGHHMJKG_02762 2.68e-28 - - - - - - - -
PGHHMJKG_02763 1.32e-218 yjbH - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PGHHMJKG_02764 8.58e-94 yjbI - - S ko:K06886 - ko00000 Bacterial-like globin
PGHHMJKG_02765 3.61e-122 yjbJ - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PGHHMJKG_02766 7.02e-128 yjbK - - S - - - protein conserved in bacteria
PGHHMJKG_02767 4.41e-80 yjbL - - S - - - Belongs to the UPF0738 family
PGHHMJKG_02768 5.06e-145 yjbM 2.7.6.5 - S ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 GTP pyrophosphokinase
PGHHMJKG_02769 2.94e-194 nadK 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGHHMJKG_02770 3.01e-202 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 - J ko:K06177,ko:K06180 - ko00000,ko01000,ko03009,ko03016 Responsible for synthesis of pseudouridine from uracil
PGHHMJKG_02771 1.15e-180 prpE 3.1.3.16, 3.6.1.41 - T ko:K01090,ko:K01525 ko00230,map00230 ko00000,ko00001,ko01000 Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PGHHMJKG_02772 0.0 yjbQ - - P ko:K03455,ko:K03499 - ko00000,ko02000 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PGHHMJKG_02773 1.91e-175 tenA 3.5.99.2 - K ko:K03707 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PGHHMJKG_02774 4.49e-136 tenI 5.3.99.10 - H ko:K10810 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000,ko03000 Transcriptional regulator TenI
PGHHMJKG_02775 1.73e-272 thiO 1.4.3.19, 1.4.5.1 - E ko:K00285,ko:K03153 ko00360,ko00730,ko01100,map00360,map00730,map01100 ko00000,ko00001,ko01000 Glycine oxidase
PGHHMJKG_02776 2.56e-40 thiS - - H ko:K03154 ko04122,map04122 ko00000,ko00001 thiamine diphosphate biosynthetic process
PGHHMJKG_02777 1.86e-171 thiG 2.8.1.10 - H ko:K03149 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko01000 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PGHHMJKG_02778 2.41e-235 thiF 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PGHHMJKG_02779 4.85e-191 thiD 2.7.1.49, 2.7.4.7 - H ko:K00941 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PGHHMJKG_02780 1.23e-182 fabI 1.3.1.10, 1.3.1.9 - I ko:K00208 ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Enoyl- acyl-carrier-protein reductase NADH
PGHHMJKG_02781 2.09e-103 yjbX - - S - - - Spore coat protein
PGHHMJKG_02782 3.92e-107 cotZ - - S ko:K06344 - ko00000 Spore coat protein
PGHHMJKG_02783 6.3e-124 cotY - - S ko:K06343 - ko00000 Spore coat protein Z
PGHHMJKG_02784 1.03e-62 cotX - - S ko:K06342 - ko00000 Spore Coat Protein X and V domain
PGHHMJKG_02785 1.51e-18 cotW - - - ko:K06341 - ko00000 -
PGHHMJKG_02787 1.23e-75 yjcA - - S - - - Protein of unknown function (DUF1360)
PGHHMJKG_02790 5.39e-52 spoVIF - - S - - - Stage VI sporulation protein F
PGHHMJKG_02791 0.0 yjcD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PGHHMJKG_02792 6.31e-51 - - - - - - - -
PGHHMJKG_02793 2.22e-93 yjcF - - S - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_02794 1.2e-121 yjcG - - J - - - Belongs to the 2H phosphoesterase superfamily. YjcG family
PGHHMJKG_02795 1.63e-178 yjcH - - P ko:K07214 - ko00000 COG2382 Enterochelin esterase and related enzymes
PGHHMJKG_02796 1.98e-273 metB 2.5.1.48 - E ko:K01739 ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PGHHMJKG_02797 1.84e-280 metC 4.4.1.8 - E ko:K01760 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 cystathionine
PGHHMJKG_02798 6.86e-126 yjcK 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Alanine acetyltransferase
PGHHMJKG_02799 8.25e-271 yjcL - - S - - - Protein of unknown function (DUF819)
PGHHMJKG_02801 1.71e-48 int7 - - L - - - Belongs to the 'phage' integrase family
PGHHMJKG_02802 3.95e-23 int7 - - L - - - Belongs to the 'phage' integrase family
PGHHMJKG_02803 3.48e-43 xkdA - - E - - - IrrE N-terminal-like domain
PGHHMJKG_02805 1.19e-42 - - - S - - - Protein of unknown function (DUF4064)
PGHHMJKG_02806 5.33e-85 - - - - - - - -
PGHHMJKG_02807 6.49e-58 - - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_02808 8.62e-21 - - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_02809 7.6e-12 - - - S - - - Helix-turn-helix domain
PGHHMJKG_02810 2.09e-103 - - - - - - - -
PGHHMJKG_02811 0.0 miaB 2.8.4.3 - J ko:K06168 - ko00000,ko01000,ko03016 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PGHHMJKG_02812 1.27e-89 ymcA 3.6.3.21 - S ko:K02028 - ko00000,ko00002,ko01000,ko02000 Belongs to the UPF0342 family
PGHHMJKG_02813 1.74e-119 cotE - - S ko:K06328 - ko00000 Spore coat protein
PGHHMJKG_02814 0.0 mutS - - L ko:K03555 ko03430,map03430 ko00000,ko00001,ko03400 that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PGHHMJKG_02815 0.0 mutL - - L ko:K03572 ko03430,map03430 ko00000,ko00001,ko03400 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PGHHMJKG_02820 5.52e-31 - - - M - - - ArpU family transcriptional regulator
PGHHMJKG_02821 5.89e-58 - - - L - - - Phage integrase family
PGHHMJKG_02828 0.0 yvaQ - - NT ko:K03406 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko02035 chemotaxis protein
PGHHMJKG_02829 3.85e-72 yvaP - - K - - - transcriptional
PGHHMJKG_02830 9.82e-92 yvaO - - K ko:K22299 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PGHHMJKG_02831 6.83e-92 yvaO - - K ko:K22299 - ko00000,ko03000 transcriptional
PGHHMJKG_02832 4.9e-48 yvzC - - K - - - transcriptional
PGHHMJKG_02833 2.84e-194 yvaM 1.11.1.10 - S ko:K00433 - ko00000,ko01000 Serine aminopeptidase, S33
PGHHMJKG_02834 1.87e-35 secG - - U ko:K03075 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Preprotein translocase subunit SecG
PGHHMJKG_02835 3.43e-183 est 3.1.1.1 - S ko:K03928 - ko00000,ko01000 Carboxylesterase
PGHHMJKG_02836 0.0 rnr - - K ko:K12573 ko03018,map03018 ko00000,ko00001,ko01000,ko03016,ko03019 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PGHHMJKG_02837 2.4e-107 smpB - - O ko:K03664 - ko00000 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PGHHMJKG_02839 2.09e-81 - - - S - - - Phage integrase family
PGHHMJKG_02840 4.26e-43 - - - S - - - Phage integrase family
PGHHMJKG_02841 3.21e-78 - - - - - - - -
PGHHMJKG_02843 9.99e-59 - - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_02844 2.6e-09 - - - T ko:K21405 - ko00000,ko03000 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PGHHMJKG_02847 1.81e-114 - - - L - - - Conserved phage C-terminus (Phg_2220_C)
PGHHMJKG_02848 1.04e-21 - - - L ko:K02315 - ko00000,ko03032 IstB-like ATP binding protein
PGHHMJKG_02849 1.76e-10 - - - - - - - -
PGHHMJKG_02850 3.35e-56 - - - - - - - -
PGHHMJKG_02852 2.63e-264 yurR 1.4.5.1 - E ko:K00285 ko00360,map00360 ko00000,ko00001,ko01000 COG0665 Glycine D-amino acid oxidases (deaminating)
PGHHMJKG_02853 1.2e-87 yurQ - - L - - - COG0322 Nuclease subunit of the excinuclease complex
PGHHMJKG_02854 9.11e-236 frlB - - M ko:K10708 - ko00000,ko01000 Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PGHHMJKG_02855 2.46e-308 yurO - - G ko:K10117 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1653 ABC-type sugar transport system, periplasmic component
PGHHMJKG_02856 2.05e-198 yurN - - G ko:K10118 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Binding-protein-dependent transport system inner membrane component
PGHHMJKG_02857 1.29e-89 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PGHHMJKG_02858 4.53e-107 - - - P ko:K10119 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0395 ABC-type sugar transport system, permease component
PGHHMJKG_02859 9.57e-209 - 2.7.1.218 - G ko:K10710 - ko00000,ko01000 pfkB family carbohydrate kinase
PGHHMJKG_02860 8.71e-175 frlR1 - - K ko:K03710,ko:K10711 - ko00000,ko03000 UTRA
PGHHMJKG_02861 2.83e-261 msmX - - P ko:K10112 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the ABC transporter superfamily
PGHHMJKG_02862 4.42e-216 bsn - - L - - - Ribonuclease
PGHHMJKG_02863 9.41e-92 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PGHHMJKG_02864 9e-172 pucF 3.5.3.9 - E ko:K02083 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000,ko01002 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PGHHMJKG_02865 9.52e-303 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 - E ko:K00830,ko:K00839 ko00230,ko00250,ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko04146,map00230,map00250,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200,map04146 ko00000,ko00001,ko00002,ko01000,ko01007 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PGHHMJKG_02866 7.18e-234 pucA 1.17.1.4 - O ko:K00087,ko:K07402 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PGHHMJKG_02867 4.18e-141 pucB 1.17.1.4, 2.7.7.76 - S ko:K00087,ko:K07141 ko00230,ko00790,ko01100,ko01120,map00230,map00790,map01100,map01120 ko00000,ko00001,ko00002,ko01000 MobA-like NTP transferase domain
PGHHMJKG_02868 2.47e-187 pucC 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03519 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PGHHMJKG_02869 0.0 pucD 1.17.1.4 - C ko:K00087 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PGHHMJKG_02870 1.7e-122 - 1.17.1.4, 1.2.5.3 - C ko:K00087,ko:K03518 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PGHHMJKG_02871 0.000154 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PGHHMJKG_02873 2.09e-72 pucM 3.5.2.17 - S ko:K07127 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko02000 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
PGHHMJKG_02874 0.0 - 1.7.3.3, 4.1.1.97 - Q ko:K16838 ko00230,ko00232,ko01100,ko01120,map00230,map00232,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
PGHHMJKG_02875 4.37e-273 pbuX - - F ko:K16169,ko:K16170 - ko00000,ko02000 xanthine
PGHHMJKG_02876 2.82e-298 pbuX - - F ko:K03458,ko:K16169,ko:K16170 - ko00000,ko02000 Permease family
PGHHMJKG_02877 0.0 pucR - - QT ko:K09684 - ko00000,ko03000 COG2508 Regulator of polyketide synthase expression
PGHHMJKG_02878 0.0 allB 3.5.2.5 - F ko:K01466 ko00230,ko01100,ko01120,map00230,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PGHHMJKG_02879 1.07e-79 yunG - - - - - - -
PGHHMJKG_02880 4.26e-220 yunF - - S - - - Protein of unknown function DUF72
PGHHMJKG_02881 7.59e-180 yunE - - S ko:K07090 - ko00000 membrane transporter protein
PGHHMJKG_02882 0.0 yunD 3.1.3.5 - F ko:K01081 ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110 ko00000,ko00001,ko01000 Belongs to the 5'-nucleotidase family
PGHHMJKG_02883 5.67e-64 yunC - - S - - - Domain of unknown function (DUF1805)
PGHHMJKG_02884 3.49e-169 yunB - - S - - - Sporulation protein YunB (Spo_YunB)
PGHHMJKG_02885 1.08e-251 lytH - - M ko:K21472 - ko00000,ko01000,ko01002,ko01011 Peptidase, M23
PGHHMJKG_02886 1.37e-215 lipA 2.8.1.8 - H ko:K03644 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PGHHMJKG_02887 1.34e-144 yutC - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PGHHMJKG_02888 3.2e-63 yutD - - S - - - protein conserved in bacteria
PGHHMJKG_02889 1.61e-97 yutE - - S - - - Protein of unknown function DUF86
PGHHMJKG_02890 2.13e-182 nagD 3.1.3.41 - G ko:K01101 ko00627,ko01120,map00627,map01120 ko00000,ko00001,ko01000 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PGHHMJKG_02891 3.34e-112 yutG 3.1.3.27 - I ko:K01095 ko00564,ko01100,map00564,map01100 ko00000,ko00001,ko01000 COG1267 Phosphatidylglycerophosphatase A and related proteins
PGHHMJKG_02892 2.57e-252 yutH - - S - - - Spore coat protein
PGHHMJKG_02893 6.79e-307 hom 1.1.1.3 - E ko:K00003 ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 homoserine dehydrogenase
PGHHMJKG_02894 9.76e-253 thrC 4.2.3.1 - E ko:K01733 ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PGHHMJKG_02895 2.99e-220 thrB 2.7.1.39 - E ko:K00872 ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PGHHMJKG_02896 0.0 yuxL 3.4.19.1 - EU ko:K01303 - ko00000,ko01000,ko01002 peptidase
PGHHMJKG_02897 1.26e-47 yutI - - O - - - COG0694 Thioredoxin-like proteins and domains
PGHHMJKG_02898 5.44e-74 yuzD - - S - - - protein conserved in bacteria
PGHHMJKG_02899 1.12e-253 yutJ 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PGHHMJKG_02900 1.74e-52 yuzB - - S - - - Belongs to the UPF0349 family
PGHHMJKG_02901 1.8e-177 gmT1 - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGHHMJKG_02902 2.44e-210 - - - K - - - AraC-like ligand binding domain
PGHHMJKG_02903 2.27e-220 ydeD - - EG - - - COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PGHHMJKG_02904 7.62e-210 ydeE - - K ko:K13653 - ko00000,ko03000 AraC family transcriptional regulator
PGHHMJKG_02905 0.0 - - - K - - - COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGHHMJKG_02906 1.34e-196 ydeG - - EGP - - - Major facilitator superfamily
PGHHMJKG_02907 4.72e-134 ydeI - - S - - - Bacteriocin-protection, YdeI or OmpD-Associated
PGHHMJKG_02908 4.95e-140 - - - - - - - -
PGHHMJKG_02909 2.4e-41 - - - S - - - SNARE associated Golgi protein
PGHHMJKG_02910 3.3e-19 ptsH - - G ko:K11189 - ko00000,ko02000 PTS HPr component phosphorylation site
PGHHMJKG_02911 2.44e-110 - - - K - - - Transcriptional regulator C-terminal region
PGHHMJKG_02912 4.66e-197 ydeK - - EG - - - -transporter
PGHHMJKG_02913 0.0 ydeL - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGHHMJKG_02914 2.49e-95 ydeM1 - - I - - - N-terminal half of MaoC dehydratase
PGHHMJKG_02915 1.37e-134 - - - S ko:K07002 - ko00000 Serine hydrolase
PGHHMJKG_02916 1.02e-72 - - - K - - - HxlR-like helix-turn-helix
PGHHMJKG_02917 9.32e-194 ydeO - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PGHHMJKG_02918 3e-75 arsR - - K ko:K03892,ko:K22043 - ko00000,ko03000 transcriptional
PGHHMJKG_02919 1.75e-294 arsB - - P ko:K03893 - ko00000,ko02000 Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PGHHMJKG_02920 8.66e-186 - - - J - - - GNAT acetyltransferase
PGHHMJKG_02921 9.99e-197 - - - EG - - - EamA-like transporter family
PGHHMJKG_02922 0.0 ydfD - - K ko:K18907 - ko00000,ko00002,ko01504,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGHHMJKG_02923 1.54e-232 - 4.1.1.86 - E ko:K13745 ko00260,ko01120,map00260,map01120 ko00000,ko00001,ko01000 Pyridoxal-dependent decarboxylase conserved domain
PGHHMJKG_02924 4.04e-149 ydfE - - S - - - Flavin reductase like domain
PGHHMJKG_02925 5.24e-159 ydfF - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PGHHMJKG_02926 1.15e-20 - - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGHHMJKG_02928 3.75e-249 ydfH 2.7.13.3 - T ko:K11623 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_02929 1.55e-140 ydfI - - K ko:K11624 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_02930 0.0 ydfJ - - S ko:K06994,ko:K11625 ko02020,map02020 ko00000,ko00001 drug exporters of the RND superfamily
PGHHMJKG_02931 1.89e-40 - - - - - - - -
PGHHMJKG_02932 5.5e-37 - - - S ko:K21492 - ko00000,ko02048 Suppressor of fused protein (SUFU)
PGHHMJKG_02936 5.24e-60 - - - - - - - -
PGHHMJKG_02937 1.1e-20 - - - S - - - SMI1 / KNR4 family
PGHHMJKG_02938 5.52e-37 - - - S - - - SMI1-KNR4 cell-wall
PGHHMJKG_02940 3.4e-49 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
PGHHMJKG_02941 1.72e-221 - - - L ko:K21487 - ko00000,ko01000,ko02048 nucleic acid phosphodiester bond hydrolysis
PGHHMJKG_02942 3.2e-13 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PGHHMJKG_02943 4.93e-266 - - - S ko:K06366 ko02024,map02024 ko00000,ko00001,ko01000 Aspartate phosphatase response regulator
PGHHMJKG_02945 8.28e-87 - - - K - - - Glyoxalase bleomycin resistance protein dioxygenase
PGHHMJKG_02946 1.14e-197 yybE - - K - - - Transcriptional regulator
PGHHMJKG_02947 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PGHHMJKG_02948 7.53e-161 sigK - - K ko:K03091 - ko00000,ko03021 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_02949 2.53e-97 nucB - - M - - - Deoxyribonuclease NucA/NucB
PGHHMJKG_02950 7.4e-168 - - - - - - - -
PGHHMJKG_02951 7.31e-215 yqeC 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 6-phosphogluconate dehydrogenase
PGHHMJKG_02952 9.36e-135 yqeD - - S - - - SNARE associated Golgi protein
PGHHMJKG_02953 2.3e-174 xlyA 3.5.1.28 - M ko:K01447 - ko00000,ko01000 n-acetylmuramoyl-L-alanine amidase
PGHHMJKG_02954 2.24e-182 yqeF - - E - - - GDSL-like Lipase/Acylhydrolase
PGHHMJKG_02956 2.17e-123 yqeG - - S ko:K07015 - ko00000 hydrolase of the HAD superfamily
PGHHMJKG_02957 4.78e-273 yqeH - - S ko:K06948 - ko00000,ko03009 In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PGHHMJKG_02958 8.1e-199 aroE 1.1.1.25 - E ko:K00014 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PGHHMJKG_02959 8.95e-61 yhbY - - J ko:K07574 - ko00000,ko03009 RNA-binding protein containing KH domain, possibly ribosomal protein
PGHHMJKG_02960 2.47e-141 nadD 2.7.7.18 - H ko:K00969 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PGHHMJKG_02961 3.95e-132 yqeK - - H - - - HD superfamily hydrolase involved in NAD metabolism
PGHHMJKG_02962 1.14e-80 rsfS - - J ko:K09710 - ko00000,ko03009 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PGHHMJKG_02963 7.73e-176 yqeM - - Q - - - Methyltransferase
PGHHMJKG_02964 4.46e-188 comER - - E ko:K02239 - ko00000,ko00002,ko02044 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGHHMJKG_02965 3.69e-135 comEA - - L ko:K02237 - ko00000,ko00002,ko02044 COG1555 DNA uptake protein and related DNA-binding proteins
PGHHMJKG_02966 3.25e-137 comEB 3.5.4.12 - F ko:K01493 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000,ko02044 ComE operon protein 2
PGHHMJKG_02967 0.0 comEC - - S ko:K02238 - ko00000,ko00002,ko02044 Competence protein ComEC
PGHHMJKG_02968 2.36e-22 - - - S - - - YqzM-like protein
PGHHMJKG_02969 4.06e-244 holA 2.7.7.7 - L ko:K02340 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III delta subunit
PGHHMJKG_02970 4e-49 rpsT - - J ko:K02968 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 16S ribosomal RNA
PGHHMJKG_02971 3.42e-258 gpr 3.4.24.78 - C ko:K06012 - ko00000,ko01000,ko01002 Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PGHHMJKG_02972 2.73e-283 spoIIP - - M ko:K06385 - ko00000 stage II sporulation protein P
PGHHMJKG_02973 7.06e-70 yqxA - - S - - - Protein of unknown function (DUF3679)
PGHHMJKG_02974 0.0 lepA - - M ko:K03596 ko05134,map05134 ko00000,ko00001 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PGHHMJKG_02975 5.86e-276 hemN - - H - - - Involved in the biosynthesis of porphyrin-containing compound
PGHHMJKG_02976 3.88e-240 hrcA - - K ko:K03705 - ko00000,ko03000 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PGHHMJKG_02977 4.36e-116 grpE - - O ko:K03687 - ko00000,ko03029,ko03110 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PGHHMJKG_02978 0.0 dnaK - - O ko:K04043 ko03018,ko04212,ko05152,map03018,map04212,map05152 ko00000,ko00001,ko03019,ko03029,ko03110,ko04147 Heat shock 70 kDa protein
PGHHMJKG_02979 3.41e-257 dnaJ - - O ko:K03686 - ko00000,ko03029,ko03110 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PGHHMJKG_02980 2.29e-225 prmA - - J ko:K02687 - ko00000,ko01000,ko03009 Methylates ribosomal protein L11
PGHHMJKG_02981 6.85e-179 rsmE 2.1.1.193 - J ko:K09761 - ko00000,ko01000,ko03009 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PGHHMJKG_02982 0.0 yqeV 2.8.4.5 - J ko:K18707 - ko00000,ko01000,ko03016 ribosomal protein S12 methylthiotransferase
PGHHMJKG_02983 4.64e-201 yqeW - - P ko:K03324 - ko00000,ko02000 COG1283 Na phosphate symporter
PGHHMJKG_02984 1.03e-26 rpsU - - J ko:K02970 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bS21 family
PGHHMJKG_02985 4.53e-90 yqeY - - S ko:K09117 - ko00000 Yqey-like protein
PGHHMJKG_02986 3.78e-290 yqeZ - - O ko:K07403 - ko00000 COG1030 Membrane-bound serine protease (ClpP class)
PGHHMJKG_02987 4.35e-192 yqfA - - S - - - UPF0365 protein
PGHHMJKG_02988 2.23e-56 yqfB - - - - - - -
PGHHMJKG_02989 2.07e-60 yqfC - - S - - - sporulation protein YqfC
PGHHMJKG_02990 8.52e-242 yqfD - - S ko:K06438 - ko00000 Stage IV sporulation
PGHHMJKG_02991 4.99e-224 phoH - - T ko:K06217 - ko00000 Phosphate starvation-inducible protein PhoH
PGHHMJKG_02993 0.0 yqfF - - S ko:K07037 - ko00000 membrane-associated HD superfamily hydrolase
PGHHMJKG_02994 1.75e-105 ybeY - - S ko:K07042 - ko00000,ko03009 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PGHHMJKG_02995 3.34e-80 dgkA 2.7.1.107, 2.7.1.66 - M ko:K00887,ko:K00901 ko00550,ko00561,ko00564,ko01100,ko01110,ko04070,ko04072,ko05231,map00550,map00561,map00564,map01100,map01110,map04070,map04072,map05231 ko00000,ko00001,ko01000 Diacylglycerol kinase
PGHHMJKG_02996 5.52e-92 cdd 3.5.4.5 - F ko:K01489 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko01000 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PGHHMJKG_02997 9.98e-215 era - - S ko:K03595 - ko00000,ko03009,ko03029 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PGHHMJKG_02998 5.29e-27 - - - S - - - YqzL-like protein
PGHHMJKG_02999 2.14e-186 recO - - L ko:K03584 ko03440,map03440 ko00000,ko00001,ko03400 Involved in DNA repair and RecF pathway recombination
PGHHMJKG_03000 2.12e-222 glyQ 6.1.1.14 - J ko:K01878 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 glycyl-tRNA synthetase alpha subunit
PGHHMJKG_03001 0.0 glyS 6.1.1.14 - J ko:K01879 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Glycyl-tRNA synthetase beta subunit
PGHHMJKG_03002 3.29e-144 ccpN - - K - - - CBS domain
PGHHMJKG_03003 6.38e-191 yqfL 2.7.11.33, 2.7.4.28 - S ko:K09773 - ko00000,ko01000 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PGHHMJKG_03004 6.03e-114 yqxD - - S ko:K09768 - ko00000 Belongs to the UPF0178 family
PGHHMJKG_03005 0.0 dnaG - - L ko:K02316 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PGHHMJKG_03006 2.29e-253 sigA - - K ko:K03086 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PGHHMJKG_03007 1.61e-81 cccA - - C ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PGHHMJKG_03008 1.98e-149 trmK 2.1.1.217 - S ko:K06967 - ko00000,ko01000,ko03016 SAM-dependent methyltransferase
PGHHMJKG_03009 7.29e-267 yqfO - - S - - - Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PGHHMJKG_03010 1.01e-225 ispH 1.17.7.4 - IM ko:K03527 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PGHHMJKG_03011 1.05e-48 yqfQ - - S - - - YqfQ-like protein
PGHHMJKG_03012 1.09e-310 cshB 3.6.4.13 - JKL ko:K05592,ko:K18692 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PGHHMJKG_03013 1.04e-214 nfo 3.1.21.2 - L ko:K01151 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PGHHMJKG_03014 3.01e-49 yqfT - - S - - - Protein of unknown function (DUF2624)
PGHHMJKG_03015 2.21e-198 yqfU - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PGHHMJKG_03016 8.59e-107 zur - - P ko:K02076 - ko00000,ko03000 Belongs to the Fur family
PGHHMJKG_03017 8.25e-142 yqfW - - S ko:K05967 - ko00000 Belongs to the 5'(3')-deoxyribonucleotidase family
PGHHMJKG_03018 2.38e-80 yqfX - - S - - - membrane
PGHHMJKG_03019 5.22e-257 ispG 1.17.7.1, 1.17.7.3 - I ko:K03526 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PGHHMJKG_03020 1.35e-61 yqfZ - - M ko:K06417 - ko00000 LysM domain
PGHHMJKG_03021 1.12e-167 yqgB - - S - - - Protein of unknown function (DUF1189)
PGHHMJKG_03022 2.36e-100 yqgC - - S ko:K09793 - ko00000 protein conserved in bacteria
PGHHMJKG_03023 1.59e-148 sodA 1.15.1.1 - P ko:K04564 ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016 ko00000,ko00001,ko01000 radicals which are normally produced within the cells and which are toxic to biological systems
PGHHMJKG_03024 3.96e-293 yqgE - - EGP ko:K08222 - ko00000,ko02000 Major facilitator superfamily
PGHHMJKG_03025 0.0 pbpA - - M ko:K21465,ko:K21466 ko00550,map00550 ko00000,ko00001,ko01011 penicillin-binding protein
PGHHMJKG_03026 2.61e-205 pstS - - P ko:K02040 ko02010,ko02020,ko05152,map02010,map02020,map05152 ko00000,ko00001,ko00002,ko02000 Phosphate
PGHHMJKG_03027 7.11e-203 pstC - - P ko:K02037 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 probably responsible for the translocation of the substrate across the membrane
PGHHMJKG_03028 5.26e-202 pstA - - P ko:K02038 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Phosphate transport system permease
PGHHMJKG_03029 1.14e-188 pstBA 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGHHMJKG_03030 1.57e-186 pstB 3.6.3.27 - P ko:K02036 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PGHHMJKG_03031 1.09e-93 yqzC - - S - - - YceG-like family
PGHHMJKG_03032 2.81e-67 yqzD - - - - - - -
PGHHMJKG_03034 1.94e-248 yqgM 2.4.1.250 - M ko:K15521 - ko00000,ko01000 Glycosyl transferases group 1
PGHHMJKG_03035 6.25e-29 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PGHHMJKG_03036 4.62e-136 fthC 6.3.3.2 - H ko:K01934 ko00670,ko01100,map00670,map01100 ko00000,ko00001,ko01000 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PGHHMJKG_03037 3.38e-14 yqgO - - - - - - -
PGHHMJKG_03038 0.0 gluP 3.4.21.105 - O ko:K19225 - ko00000,ko01000,ko01002 membrane protein (homolog of Drosophila rhomboid)
PGHHMJKG_03039 9.15e-45 yqgQ - - S - - - Protein conserved in bacteria
PGHHMJKG_03040 3.28e-230 glcK 2.7.1.2 - G ko:K00845 ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Glucokinase
PGHHMJKG_03041 0.0 yqgS 2.7.8.20 - M ko:K01138,ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PGHHMJKG_03042 3.55e-282 yqgT 3.4.19.11 - E ko:K01308 - ko00000,ko01000,ko01002 Gamma-D-glutamyl-L-diamino acid endopeptidase
PGHHMJKG_03043 2.69e-256 yqgU - - - - - - -
PGHHMJKG_03044 7.34e-66 yqgV - - S - - - Thiamine-binding protein
PGHHMJKG_03045 1.91e-31 yqgW - - S - - - Protein of unknown function (DUF2759)
PGHHMJKG_03046 1.3e-156 yqgX 3.1.2.6 - S ko:K01069 ko00620,map00620 ko00000,ko00001,ko01000 COG0491 Zn-dependent hydrolases, including glyoxylases
PGHHMJKG_03047 6.92e-17 cwlJ 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Cell wall
PGHHMJKG_03048 1.66e-100 hsp - - O ko:K13993 ko04141,map04141 ko00000,ko00001,ko03110 Hsp20/alpha crystallin family
PGHHMJKG_03049 9.06e-47 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
PGHHMJKG_03050 0.0 fbp 3.1.3.11 - G ko:K04041 ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Firmicute fructose-1,6-bisphosphatase
PGHHMJKG_03051 8.4e-143 - - - P ko:K16917 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGHHMJKG_03052 9.5e-153 - - - S ko:K16916 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PGHHMJKG_03053 1.95e-159 yydK - - K ko:K03489 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_03054 4.15e-14 bglP - - G ko:K02755,ko:K02756,ko:K02757 ko02060,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_03055 0.0 bglA 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGHHMJKG_03056 0.0 ahpF - - O ko:K03387 - ko00000,ko01000 Alkyl hydroperoxide reductase
PGHHMJKG_03057 2.68e-135 ahpC 1.11.1.15 - O ko:K03386 ko04214,map04214 ko00000,ko00001,ko01000,ko04147 Alkyl hydroperoxide reductase
PGHHMJKG_03058 0.0 gntZ 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PGHHMJKG_03059 1.18e-294 gntP - - EG ko:K03299 - ko00000,ko02000 COG2610 H gluconate symporter and related permeases
PGHHMJKG_03060 0.0 gntK 2.7.1.12 - G ko:K00851 ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko01000 Belongs to the FGGY kinase family
PGHHMJKG_03061 1.27e-163 gntR - - K ko:K11476 - ko00000,ko03000 transcriptional
PGHHMJKG_03062 2e-264 glxK 2.7.1.165 - G ko:K00865 ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130 ko00000,ko00001,ko01000 Belongs to the glycerate kinase type-1 family
PGHHMJKG_03063 7.3e-245 - - - GM ko:K19426 - ko00000,ko01000 Polysaccharide pyruvyl transferase
PGHHMJKG_03064 2.19e-153 yxaC - - M - - - effector of murein hydrolase
PGHHMJKG_03065 2.53e-78 - - - S ko:K06518 - ko00000,ko02000 LrgA family
PGHHMJKG_03066 6.83e-94 - - - K - - - helix_turn_helix multiple antibiotic resistance protein
PGHHMJKG_03067 2.49e-254 yxnA - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_03068 1.12e-129 yxaF - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PGHHMJKG_03069 5.18e-251 - 1.13.11.24 - S ko:K07155 - ko00000,ko01000 AraC-like ligand binding domain
PGHHMJKG_03070 1.46e-283 - - - P ko:K07148 - ko00000 Protein of unknown function (DUF418)
PGHHMJKG_03071 1.35e-97 yxaI - - S - - - membrane protein domain
PGHHMJKG_03072 7.97e-83 - - - S - - - Family of unknown function (DUF5391)
PGHHMJKG_03073 2.54e-43 yxaI - - S - - - membrane protein domain
PGHHMJKG_03074 3.42e-313 aldX 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PGHHMJKG_03075 6.97e-264 yxbF - - K - - - Bacterial regulatory proteins, tetR family
PGHHMJKG_03076 2.01e-156 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PGHHMJKG_03077 9.3e-23 yxbG - - IQ - - - Enoyl-(Acyl carrier protein) reductase
PGHHMJKG_03079 0.0 htpG - - O ko:K04079 ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418 ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147 Molecular chaperone. Has ATPase activity
PGHHMJKG_03080 2.4e-233 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGHHMJKG_03081 2.22e-38 csbC - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGHHMJKG_03082 1.05e-101 - - - T - - - HPP family
PGHHMJKG_03084 7.27e-55 - - - - - - - -
PGHHMJKG_03085 2.04e-223 iolS - - C ko:K06607 - ko00000,ko01000 Aldo keto reductase
PGHHMJKG_03086 1.56e-177 iolR - - K ko:K06608,ko:K11534 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PGHHMJKG_03087 0.0 iolA 1.2.1.18, 1.2.1.27 - C ko:K00140 ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGHHMJKG_03088 2.43e-200 iolB 5.3.1.30 - G ko:K03337 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PGHHMJKG_03089 1.75e-227 iolC 2.7.1.92 - G ko:K03338 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PGHHMJKG_03090 0.0 iolD 3.7.1.22 - E ko:K03336 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PGHHMJKG_03091 4.99e-222 iolE 4.2.1.44 - G ko:K03335 ko00562,ko01100,ko01120,map00562,map01100,map01120 ko00000,ko00001,ko01000 Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PGHHMJKG_03092 1.34e-294 iolF - - EGP ko:K06610 - ko00000,ko02000 Major facilitator superfamily
PGHHMJKG_03093 4.44e-251 iolG 1.1.1.18, 1.1.1.369 - S ko:K00010 ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130 ko00000,ko00001,ko01000 Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PGHHMJKG_03094 1.08e-212 iolH - - G ko:K06605 - ko00000 Xylose isomerase-like TIM barrel
PGHHMJKG_03095 2.29e-193 iolI 5.3.99.11 - G ko:K06606 ko00562,ko01120,map00562,map01120 ko00000,ko00001,ko01000 Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PGHHMJKG_03096 3.3e-203 fbaA 4.1.2.13, 4.1.2.29 - F ko:K01624,ko:K03339 ko00010,ko00030,ko00051,ko00562,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00562,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PGHHMJKG_03097 9.37e-159 yxdJ - - T ko:K02483,ko:K11634 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_03098 1.75e-227 yxdK 2.7.13.3 - T ko:K11633 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_03099 1.01e-176 yxdL - - V ko:K11635 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_03100 0.0 yxdM - - V ko:K11636 ko02020,map02020 ko00000,ko00001,ko00002,ko02000 ABC transporter (permease)
PGHHMJKG_03101 5.95e-77 yxeA - - S - - - Protein of unknown function (DUF1093)
PGHHMJKG_03102 1.55e-215 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGHHMJKG_03103 9.65e-91 - - - - - - - -
PGHHMJKG_03104 0.0 secA - - U ko:K03070 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PGHHMJKG_03105 2.33e-231 prfB - - J ko:K02836 - ko00000,ko03012 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PGHHMJKG_03106 1.31e-184 yvjA - - S - - - Uncharacterized protein conserved in bacteria (DUF2179)
PGHHMJKG_03107 3.78e-74 cccB - - C ko:K12263,ko:K13300 - ko00000 COG2010 Cytochrome c, mono- and diheme variants
PGHHMJKG_03108 3.03e-159 ftsE - - D ko:K09812 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 cell division ATP-binding protein FtsE
PGHHMJKG_03109 5.45e-199 ftsX - - D ko:K09811 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko03036 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PGHHMJKG_03110 0.0 ctpB 3.4.21.102 - M ko:K03797 - ko00000,ko01000,ko01002 Belongs to the peptidase S41A family
PGHHMJKG_03111 1.38e-73 swrA - - S - - - Swarming motility protein
PGHHMJKG_03112 3.17e-280 minJ - - O - - - COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGHHMJKG_03113 3.03e-295 yvkA - - P - - - -transporter
PGHHMJKG_03114 1.43e-131 yvkB - - K - - - Transcriptional regulator
PGHHMJKG_03115 0.0 yvkC 2.7.9.2 - GT ko:K01007 ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Phosphotransferase
PGHHMJKG_03116 2.54e-42 csbA - - S - - - protein conserved in bacteria
PGHHMJKG_03117 0.0 uvrB - - L ko:K03702 ko03420,map03420 ko00000,ko00001,ko03400 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PGHHMJKG_03118 0.0 uvrA - - L ko:K03701 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PGHHMJKG_03119 3.03e-147 hag - - N ko:K02406 ko02020,ko02040,ko04621,ko04626,ko05132,ko05134,map02020,map02040,map04621,map04626,map05132,map05134 ko00000,ko00001,ko02035 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PGHHMJKG_03120 2.25e-45 yvkN - - - - - - -
PGHHMJKG_03121 8.09e-65 yvlA - - - - - - -
PGHHMJKG_03122 5.54e-219 yvlB - - S - - - Putative adhesin
PGHHMJKG_03123 1.5e-36 yvlC - - KT ko:K03973 - ko00000,ko02048,ko03000 PspC domain
PGHHMJKG_03124 3.8e-66 yvlD - - S ko:K08972 - ko00000 Membrane
PGHHMJKG_03125 8.04e-188 nadK2 2.7.1.23 - G ko:K00858 ko00760,ko01100,map00760,map01100 ko00000,ko00001,ko01000 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PGHHMJKG_03126 3.25e-228 sppA - - OU ko:K04773 - ko00000,ko01000,ko01002 signal peptide peptidase SppA
PGHHMJKG_03127 8.23e-112 yteJ - - S - - - RDD family
PGHHMJKG_03128 6.29e-144 ytfI - - S - - - Protein of unknown function (DUF2953)
PGHHMJKG_03129 5.02e-90 ytfJ - - S - - - Sporulation protein YtfJ
PGHHMJKG_03130 1.93e-116 tpx 1.11.1.15 - O ko:K11065 - ko00000,ko01000 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PGHHMJKG_03131 6.26e-223 ytxK 2.1.1.72 - L ko:K00571 - ko00000,ko01000,ko02048 DNA methylase
PGHHMJKG_03132 4.69e-281 ackA 2.7.2.1 - F ko:K00925 ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PGHHMJKG_03133 3.31e-114 moaB 2.7.7.75 - H ko:K03638 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 May be involved in the biosynthesis of molybdopterin
PGHHMJKG_03134 1.06e-297 argG 6.3.4.5 - E ko:K01940 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the argininosuccinate synthase family. Type 1 subfamily
PGHHMJKG_03135 0.0 argH 4.3.2.1 - E ko:K01755 ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 argininosuccinate lyase
PGHHMJKG_03137 8.04e-182 ytkK 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_03138 1.91e-166 ytkL - - S - - - Belongs to the UPF0173 family
PGHHMJKG_03139 1.13e-308 ytoI - - K - - - transcriptional regulator containing CBS domains
PGHHMJKG_03140 2.15e-63 ytpI - - S - - - YtpI-like protein
PGHHMJKG_03141 1.24e-230 nrnA 3.1.13.3, 3.1.3.7 - S ko:K06881 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko01000,ko03400 COG0618 Exopolyphosphatase-related proteins
PGHHMJKG_03142 1.15e-39 - - - - - - - -
PGHHMJKG_03143 5.12e-112 ytrI - - - - - - -
PGHHMJKG_03144 2.45e-75 ytrH - - S - - - Sporulation protein YtrH
PGHHMJKG_03145 0.0 dnaE 2.7.7.7 - L ko:K02337 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase
PGHHMJKG_03146 1.21e-286 ytsJ 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 Malate dehydrogenase
PGHHMJKG_03147 5.1e-207 accD 2.1.3.15, 6.4.1.2 - I ko:K01963 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PGHHMJKG_03148 9.82e-234 accA 2.1.3.15, 6.4.1.2 - I ko:K01962 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PGHHMJKG_03149 4.65e-229 pfkA 2.7.1.11 - F ko:K00850 ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230 ko00000,ko00001,ko00002,ko01000,ko01009,ko03019 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PGHHMJKG_03150 0.0 pyk 2.7.1.40 - G ko:K00873 ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the pyruvate kinase family
PGHHMJKG_03151 2.71e-81 fxsA - - S ko:K07113 - ko00000 COG3030 Protein affecting phage T7 exclusion by the F plasmid
PGHHMJKG_03152 2.24e-244 ytvI - - S - - - sporulation integral membrane protein YtvI
PGHHMJKG_03153 9.38e-95 ytwI - - S - - - membrane
PGHHMJKG_03156 0.0 glmS 2.6.1.16 - M ko:K00820 ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931 ko00000,ko00001,ko01000,ko01002 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PGHHMJKG_03157 0.0 glmM 5.4.2.10 - G ko:K03431 ko00520,ko01100,ko01130,map00520,map01100,map01130 ko00000,ko00001,ko01000 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PGHHMJKG_03158 3.55e-291 ybbR - - S - - - protein conserved in bacteria
PGHHMJKG_03159 5.43e-189 dacA 2.7.7.85 - S ko:K18672 - ko00000,ko01000 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PGHHMJKG_03160 3.19e-151 rsiW - - K - - - Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PGHHMJKG_03161 9.27e-127 sigW - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_03167 9.88e-100 ybbK - - S - - - Protein of unknown function (DUF523)
PGHHMJKG_03168 8.99e-114 ybbJ - - J - - - acetyltransferase
PGHHMJKG_03169 1.64e-210 murQ 4.2.1.126 - G ko:K07106 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PGHHMJKG_03170 3.14e-193 ybbH - - K - - - transcriptional
PGHHMJKG_03171 2.09e-303 ybbF 2.7.1.211 - G ko:K02808,ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_03172 0.0 ybbE 3.4.16.4 - V ko:K21469 ko00550,map00550 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the UPF0214 family
PGHHMJKG_03173 0.0 ybbD 3.2.1.52 - G ko:K01207 ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501 ko00000,ko00001,ko00002,ko01000 Belongs to the glycosyl hydrolase 3 family
PGHHMJKG_03174 8.03e-21 ybbC - - S - - - protein conserved in bacteria
PGHHMJKG_03175 6.63e-270 ybbC - - S - - - protein conserved in bacteria
PGHHMJKG_03176 0.0 ybbB - - K ko:K21701 - ko00000,ko03000 COG2207 AraC-type DNA-binding domain-containing proteins
PGHHMJKG_03177 2.54e-216 feuA - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Iron-uptake system-binding protein
PGHHMJKG_03178 5.81e-226 feuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03179 1.43e-227 feuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03180 5.12e-173 ybbA - - S ko:K07017 - ko00000 Putative esterase
PGHHMJKG_03181 5.36e-203 ybaS - - S - - - Na -dependent transporter
PGHHMJKG_03183 0.0 ybaR - - P ko:K03321 - ko00000,ko02000 COG0659 Sulfate permease and related transporters (MFS superfamily)
PGHHMJKG_03184 3.84e-87 res - - L - - - Resolvase, N terminal domain
PGHHMJKG_03185 6.97e-98 - 3.1.21.3 - L ko:K01154 - ko00000,ko01000,ko02048 Type I restriction modification DNA specificity domain
PGHHMJKG_03186 0.0 hsdM 2.1.1.72 - V ko:K03427 - ko00000,ko01000,ko02048 Type I restriction-modification system
PGHHMJKG_03187 0.0 hsdR 3.1.21.3 - L ko:K01153 - ko00000,ko01000,ko02048 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PGHHMJKG_03190 3.17e-170 - - - L - - - Phage integrase family
PGHHMJKG_03192 4.05e-119 ysnB - - S ko:K07095 - ko00000 Phosphoesterase
PGHHMJKG_03193 3.05e-132 rdgB 3.6.1.66 - F ko:K02428 ko00230,map00230 ko00000,ko00001,ko01000 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PGHHMJKG_03194 4.12e-170 rph 2.7.7.56 - J ko:K00989 - ko00000,ko01000,ko03016 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PGHHMJKG_03195 8.03e-256 gerM - - S ko:K06298 - ko00000 COG5401 Spore germination protein
PGHHMJKG_03196 1.15e-196 murI 3.6.1.66, 5.1.1.3 - M ko:K01776,ko:K02428 ko00230,ko00471,ko01100,map00230,map00471,map01100 ko00000,ko00001,ko01000,ko01011 Provides the (R)-glutamate required for cell wall biosynthesis
PGHHMJKG_03197 1.6e-98 ysmB - - K - - - helix_turn_helix multiple antibiotic resistance protein
PGHHMJKG_03198 1.81e-41 gerE - - K ko:K01994 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_03199 1.26e-100 ysmA - - S ko:K07107 - ko00000,ko01000 thioesterase
PGHHMJKG_03200 1.15e-189 sdhB 1.3.5.1, 1.3.5.4 - C ko:K00240 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PGHHMJKG_03201 0.0 sdhA 1.3.5.1, 1.3.5.4 - C ko:K00239 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134 ko00000,ko00001,ko00002,ko01000 succinate dehydrogenase
PGHHMJKG_03202 1.35e-140 sdhC - - C ko:K00241 ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002 succinate dehydrogenase
PGHHMJKG_03203 8.53e-104 yslB - - S - - - Protein of unknown function (DUF2507)
PGHHMJKG_03204 1.13e-274 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PGHHMJKG_03205 0.0 uvrC - - L ko:K03703 ko03420,map03420 ko00000,ko00001,ko03400 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PGHHMJKG_03206 1.12e-69 trxA - - O ko:K03671 ko04621,ko05418,map04621,map05418 ko00000,ko00001,ko03110 Belongs to the thioredoxin family
PGHHMJKG_03207 0.0 xsa 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 Alpha-L-arabinofuranosidase C-terminus
PGHHMJKG_03209 5e-227 etfA - - C ko:K03522 - ko00000,ko04147 Electron transfer flavoprotein
PGHHMJKG_03210 2.58e-179 etfB - - C ko:K03521 - ko00000 Electron transfer flavoprotein
PGHHMJKG_03211 5.17e-175 fadB 4.2.1.17 - I ko:K13767 ko00071,ko00362,ko01100,ko01120,ko01212,map00071,map00362,map01100,map01120,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the enoyl-CoA hydratase isomerase family
PGHHMJKG_03212 5.74e-129 fadR - - K ko:K13770 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_03213 0.0 lcfA 6.2.1.3 - IQ ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PGHHMJKG_03214 3.76e-89 yshE - - S ko:K08989 - ko00000 membrane
PGHHMJKG_03215 0.0 mutS2 - - L ko:K07456 ko03430,map03430 ko00000,ko00001,ko03400 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PGHHMJKG_03216 0.0 polX - - L ko:K02347 - ko00000,ko03400 COG1796 DNA polymerase IV (family X)
PGHHMJKG_03217 1.09e-111 yshB - - S - - - membrane protein, required for colicin V production
PGHHMJKG_03218 1.04e-54 zapA - - D ko:K09888 - ko00000,ko03036 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PGHHMJKG_03219 8.48e-215 rnhC 3.1.26.4 - L ko:K03471 ko03030,map03030 ko00000,ko00001,ko01000,ko03032 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PGHHMJKG_03220 0.0 pheT 6.1.1.20 - J ko:K01890 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PGHHMJKG_03221 7.36e-250 pheS 6.1.1.20 - J ko:K01889 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PGHHMJKG_03222 7.68e-172 spoU - - J ko:K03437 - ko00000,ko03016 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PGHHMJKG_03223 7.54e-44 sspI - - S ko:K06426 - ko00000 Belongs to the SspI family
PGHHMJKG_03224 3.19e-263 cdaR_1 - - KT ko:K02647 - ko00000,ko03000 regulator
PGHHMJKG_03225 0.0 glcD 1.1.3.15 - C ko:K00104 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001,ko01000 Glycolate oxidase subunit
PGHHMJKG_03226 0.0 glcF - - C ko:K11473 ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130 ko00000,ko00001 Glycolate oxidase
PGHHMJKG_03227 8.42e-69 - 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 Glyoxalase-like domain
PGHHMJKG_03228 0.0 cstA - - T ko:K06200 - ko00000 Carbon starvation protein
PGHHMJKG_03229 0.0 abfA 3.2.1.55 GH51 G ko:K01209 ko00520,map00520 ko00000,ko00001,ko01000 alpha-L-arabinofuranosidase activity
PGHHMJKG_03230 4.28e-190 araQ - - G ko:K17236 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 transport system permease
PGHHMJKG_03231 7.9e-218 araP - - G ko:K17235 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PGHHMJKG_03232 0.0 araN - - G ko:K17234 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 carbohydrate transport
PGHHMJKG_03233 3.05e-281 araM 1.1.1.261 - I ko:K00096 ko00564,map00564 ko00000,ko00001,ko01000 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PGHHMJKG_03234 2.52e-61 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
PGHHMJKG_03235 1.46e-87 araL - - G ko:K02101 - ko00000 Haloacid dehalogenase-like hydrolase
PGHHMJKG_03236 1.7e-170 araD 5.1.3.4 - G ko:K03077 ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120 ko00000,ko00001,ko00002,ko01000 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PGHHMJKG_03237 0.0 araB 2.7.1.16 - C ko:K00853 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Belongs to the ribulokinase family
PGHHMJKG_03238 0.0 araA 5.3.1.4 - G ko:K01804 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Catalyzes the conversion of L-arabinose to L-ribulose
PGHHMJKG_03239 4.56e-241 - 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PGHHMJKG_03240 3.57e-261 ysdC - - G - - - COG1363 Cellulase M and related proteins
PGHHMJKG_03241 1.96e-89 ysdB - - S - - - Sigma-w pathway protein YsdB
PGHHMJKG_03242 3.65e-59 ysdA - - S - - - Membrane
PGHHMJKG_03243 3.26e-76 rplT - - J ko:K02887 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PGHHMJKG_03244 3.93e-37 rpmI - - J ko:K02916 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL35 family
PGHHMJKG_03245 1.81e-111 infC - - J ko:K02520 - ko00000,ko03012,ko03029 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PGHHMJKG_03247 1.53e-149 lrgB - - M ko:K05339 ko02020,map02020 ko00000,ko00001 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PGHHMJKG_03248 8.47e-85 lrgA - - S ko:K05338 ko02020,map02020 ko00000,ko00001,ko02000 Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PGHHMJKG_03249 1.96e-166 lytT - - T ko:K07705 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG3279 Response regulator of the LytR AlgR family
PGHHMJKG_03250 0.0 lytS 2.7.13.3 - T ko:K07704 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_03251 1.98e-189 ysaA 3.1.3.5, 3.8.1.2 - S ko:K01560,ko:K07025,ko:K08723 ko00230,ko00240,ko00361,ko00625,ko00760,ko01100,ko01110,ko01120,map00230,map00240,map00361,map00625,map00760,map01100,map01110,map01120 ko00000,ko00001,ko01000 HAD-hyrolase-like
PGHHMJKG_03252 0.0 thrS 6.1.1.3 - J ko:K01868 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PGHHMJKG_03254 2e-204 ytxC - - S - - - YtxC-like family
PGHHMJKG_03255 9.77e-144 ytxB - - S - - - SNARE associated Golgi protein
PGHHMJKG_03256 1.22e-220 dnaI - - L ko:K11144 - ko00000,ko03032 Primosomal protein DnaI
PGHHMJKG_03257 0.0 dnaB - - L ko:K03346 - ko00000,ko03032 Membrane attachment protein
PGHHMJKG_03258 2.42e-105 nrdR - - K ko:K07738 - ko00000,ko03000 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PGHHMJKG_03259 2.42e-88 speH 4.1.1.50 - E ko:K01611 ko00270,ko00330,ko01100,map00270,map00330,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PGHHMJKG_03260 9.99e-246 gapB 1.2.1.12 - G ko:K00134 ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010 ko00000,ko00001,ko00002,ko01000,ko04131,ko04147 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PGHHMJKG_03261 1.15e-86 ytcD - - K - - - Transcriptional regulator
PGHHMJKG_03262 1.6e-254 ytbD - - EGP ko:K19577 - ko00000,ko02000 -transporter
PGHHMJKG_03263 4.54e-205 ytbE - - S - - - reductase
PGHHMJKG_03264 1.63e-125 coaE 2.7.1.24 - F ko:K00859 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PGHHMJKG_03265 1.68e-138 ytaF - - P - - - Probably functions as a manganese efflux pump
PGHHMJKG_03266 4.73e-201 fpg 3.2.2.23, 4.2.99.18 - L ko:K10563 ko03410,map03410 ko00000,ko00001,ko01000,ko03400 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PGHHMJKG_03267 0.0 polA 2.7.7.7 - L ko:K02335 ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440 ko00000,ko00001,ko01000,ko03032,ko03400 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PGHHMJKG_03268 0.0 phoR 2.7.13.3 - T ko:K07636 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase
PGHHMJKG_03269 1.62e-169 phoP - - T ko:K07658 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_03270 6.01e-217 mdh 1.1.1.27, 1.1.1.37 - C ko:K00016,ko:K00024 ko00010,ko00020,ko00270,ko00620,ko00630,ko00640,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04922,map00010,map00020,map00270,map00620,map00630,map00640,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200,map04922 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the reversible oxidation of malate to oxaloacetate
PGHHMJKG_03271 2.28e-309 icd 1.1.1.42 - C ko:K00031 ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146 br01601,ko00000,ko00001,ko00002,ko01000 isocitrate
PGHHMJKG_03272 3.2e-265 citZ 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PGHHMJKG_03273 1.45e-102 ydeB - - K ko:K07736 - ko00000,ko03000 Transcription factor
PGHHMJKG_03274 4.22e-41 cspL - - K ko:K03704 - ko00000,ko03000 Cold shock
PGHHMJKG_03275 3.49e-145 ydeA - - S - - - DJ-1/PfpI family
PGHHMJKG_03279 2.98e-53 - - - - - - - -
PGHHMJKG_03280 1.8e-45 - - - K ko:K07729 - ko00000,ko03000 Helix-turn-helix XRE-family like proteins
PGHHMJKG_03281 5.9e-171 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PGHHMJKG_03282 9.99e-59 - - - - - - - -
PGHHMJKG_03283 4.64e-95 - - - J - - - Acetyltransferase (GNAT) domain
PGHHMJKG_03284 9.13e-135 ywqM - - K - - - Transcriptional regulator
PGHHMJKG_03285 4.46e-153 - - - E - - - amino acid
PGHHMJKG_03293 3.74e-108 ydcK - - S ko:K03095 - ko00000 Belongs to the SprT family
PGHHMJKG_03294 0.0 tex - - K ko:K06959 - ko00000 COG2183 Transcriptional accessory protein
PGHHMJKG_03295 1.86e-141 rsbX 3.1.3.3 - KT ko:K05518 - ko00000,ko01000,ko03021 Sigma factor PP2C-like phosphatases
PGHHMJKG_03296 1.55e-178 sigB - - K ko:K03090 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_03297 2.48e-111 rsbW 2.7.11.1 - F ko:K04757 - ko00000,ko01000,ko01001,ko03021 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PGHHMJKG_03298 1.97e-70 rsbV - - T ko:K04749 - ko00000,ko03021 Belongs to the anti-sigma-factor antagonist family
PGHHMJKG_03299 1.08e-242 rsbU 3.1.3.3 - KT ko:K07315 - ko00000,ko01000,ko03021 phosphatase
PGHHMJKG_03300 1e-88 rsbT 2.7.11.1 - T ko:K17752 - ko00000,ko01000,ko01001,ko03021 COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PGHHMJKG_03301 1.8e-74 rsbS - - T ko:K17762 - ko00000,ko03021 antagonist
PGHHMJKG_03302 8.58e-184 rsbR - - T ko:K17763 - ko00000,ko03021 Positive regulator of sigma-B
PGHHMJKG_03303 4.34e-75 ndoA - - L ko:K07171 - ko00000,ko01000,ko02048 Toxic component of a toxin-antitoxin (TA) module
PGHHMJKG_03304 9.49e-57 ndoAI - - K ko:K07723 - ko00000,ko02048,ko03000 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PGHHMJKG_03305 2.07e-281 alr 5.1.1.1, 5.1.1.5 - E ko:K01775,ko:K20707 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGHHMJKG_03306 4.66e-234 ydcC - - M - - - COG2834 Outer membrane lipoprotein-sorting protein
PGHHMJKG_03307 1.87e-76 acpS 2.7.8.7 - I ko:K00997 ko00770,map00770 ko00000,ko00001,ko01000 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PGHHMJKG_03308 2.53e-139 ydcA - - S - - - membrane protein (homolog of Drosophila rhomboid)
PGHHMJKG_03309 0.0 ydbT - - S ko:K08981 - ko00000 Membrane
PGHHMJKG_03310 2.12e-107 ydbS - - S ko:K09167 - ko00000 Bacterial PH domain
PGHHMJKG_03311 0.0 cshA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PGHHMJKG_03312 0.0 murF 6.3.2.10 - M ko:K01929 ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PGHHMJKG_03313 4.18e-256 ddl 6.3.2.4 - F ko:K01921 ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Belongs to the D-alanine--D-alanine ligase family
PGHHMJKG_03314 4.19e-75 ydbP - - CO - - - Thioredoxin
PGHHMJKG_03315 2.72e-202 yeaB - - P - - - Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PGHHMJKG_03317 1.49e-26 - - - S - - - Fur-regulated basic protein B
PGHHMJKG_03318 1.83e-280 ydbM - - I - - - acyl-CoA dehydrogenase
PGHHMJKG_03319 9.32e-70 ydbL - - - - - - -
PGHHMJKG_03320 2.99e-159 ydbK - - S ko:K01992 - ko00000,ko00002,ko02000 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PGHHMJKG_03321 2.66e-218 ydbJ - - V ko:K01990 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_03322 1.32e-230 ydbI - - S - - - AI-2E family transporter
PGHHMJKG_03323 7.33e-289 dctA - - U ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGHHMJKG_03324 3.39e-155 dctR - - T ko:K02475,ko:K11692 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG4565 Response regulator of citrate malate metabolism
PGHHMJKG_03325 0.0 dctS 2.7.13.3 - T ko:K11614,ko:K11637,ko:K11691 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Signal transduction histidine kinase regulating citrate malate metabolism
PGHHMJKG_03326 4.99e-251 dctB - - G - - - COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PGHHMJKG_03327 6.41e-197 ydbD - - P ko:K07217 - ko00000 Catalase
PGHHMJKG_03328 1.49e-81 ydbC - - S - - - Domain of unknown function (DUF4937
PGHHMJKG_03329 2.17e-78 ydbB - - G - - - Cupin domain
PGHHMJKG_03330 8.37e-11 gsiB - - S ko:K06884 - ko00000 general stress protein
PGHHMJKG_03331 4.3e-190 ydbA - - P - - - EcsC protein family
PGHHMJKG_03332 7.54e-99 ydaT - - S - - - Uncharacterized protein conserved in bacteria (DUF2188)
PGHHMJKG_03333 1.67e-42 ydaS - - S - - - membrane
PGHHMJKG_03334 7.87e-286 mntH - - P ko:K03322 - ko00000,ko02000 H( )-stimulated, divalent metal cation uptake system
PGHHMJKG_03335 6.14e-53 - - - - - - - -
PGHHMJKG_03337 2.18e-90 sdpB - - S - - - Protein conserved in bacteria
PGHHMJKG_03338 1.84e-34 - - - - - - - -
PGHHMJKG_03339 0.0 ydaP 1.2.3.3 - EH ko:K00158 ko00620,ko01100,map00620,map01100 ko00000,ko00001,ko01000 Belongs to the TPP enzyme family
PGHHMJKG_03340 5.12e-101 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 Belongs to the Nudix hydrolase family
PGHHMJKG_03341 0.0 topB 5.99.1.2 - L ko:K03169 - ko00000,ko01000,ko03032 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PGHHMJKG_03342 3.95e-98 lrpC - - K ko:K03719 - ko00000,ko03000,ko03036 Transcriptional regulator
PGHHMJKG_03343 5.19e-60 ydzA - - EGP - - - Domain of unknown function (DUF3817)
PGHHMJKG_03344 5.12e-176 amj - - U - - - Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PGHHMJKG_03345 6.13e-100 ydaG - - S - - - general stress protein
PGHHMJKG_03346 8.32e-128 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGHHMJKG_03347 2.36e-126 ydaE 5.3.1.15 - S ko:K09988 ko00040,map00040 ko00000,ko00001,ko01000 Cupin 2, conserved barrel domain protein
PGHHMJKG_03348 3.74e-207 ydaD - - IQ - - - COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_03349 1e-127 ydaC - - Q - - - Methyltransferase domain
PGHHMJKG_03350 0.0 ydaB - - IQ - - - acyl-CoA ligase
PGHHMJKG_03351 0.0 mtlR - - K ko:K03483 - ko00000,ko03000 transcriptional regulator, MtlR
PGHHMJKG_03352 8.6e-220 ycsN - - S - - - Oxidoreductase
PGHHMJKG_03353 0.0 pbpC 3.4.16.4 - M ko:K02545,ko:K21467 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko00002,ko01000,ko01011,ko01504 Penicillin-binding Protein
PGHHMJKG_03354 8.97e-65 yczJ - - S - - - biosynthesis
PGHHMJKG_03356 5.94e-154 ycsK - - E - - - anatomical structure formation involved in morphogenesis
PGHHMJKG_03357 1.55e-170 kipR - - K - - - Transcriptional regulator
PGHHMJKG_03358 1.99e-238 kipA - - E ko:K06350 - ko00000 Allophanate hydrolase subunit 2
PGHHMJKG_03359 9.77e-171 kipI - - E ko:K06351 - ko00000 Allophanate hydrolase subunit 1
PGHHMJKG_03360 7e-190 ycsI - - S - - - Belongs to the D-glutamate cyclase family
PGHHMJKG_03361 1.87e-271 ycsG - - P - - - COG1914 Mn2 and Fe2 transporters of the NRAMP family
PGHHMJKG_03362 1.1e-180 ycsF - - S ko:K07160 - ko00000 Belongs to the UPF0271 (lamB) family
PGHHMJKG_03363 1.9e-177 ycsE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Sucrose-6F-phosphate phosphohydrolase
PGHHMJKG_03364 0.0 yclG - - M - - - Pectate lyase superfamily protein
PGHHMJKG_03365 0.0 dtpT - - E ko:K03305 - ko00000 amino acid peptide transporter
PGHHMJKG_03366 6.42e-201 yclE 3.4.11.5 - S ko:K01259 ko00330,map00330 ko00000,ko00001,ko01000,ko01002 Alpha beta hydrolase
PGHHMJKG_03367 6.45e-55 yclD - - - - - - -
PGHHMJKG_03368 4.02e-52 - 4.1.1.61 - S ko:K21759 ko00627,ko01120,ko01220,map00627,map01120,map01220 ko00000,ko00001,ko01000 response to toxic substance
PGHHMJKG_03369 0.0 yclC 4.1.1.61, 4.1.1.98 - H ko:K01612,ko:K03182,ko:K16874 ko00130,ko00365,ko00627,ko01100,ko01110,ko01120,ko01220,map00130,map00365,map00627,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
PGHHMJKG_03370 2.24e-140 ubiX 2.5.1.129 - H ko:K03186 ko00130,ko00627,ko00940,ko01100,ko01110,ko01120,ko01220,map00130,map00627,map00940,map01100,map01110,map01120,map01220 ko00000,ko00001,ko00002,ko01000 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PGHHMJKG_03371 1.25e-207 yclA - - K ko:K21755 - ko00000,ko03000 LysR substrate binding domain
PGHHMJKG_03372 4.3e-188 tcyA - - ET ko:K02424 ko02010,map02010 ko00000,ko00001,ko00002,ko02000,ko02035 Belongs to the bacterial solute-binding protein 3 family
PGHHMJKG_03373 4.6e-157 tcyB - - P ko:K10009 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PGHHMJKG_03374 7.11e-172 tcyC - - E ko:K10010 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PGHHMJKG_03375 6.13e-148 yczE - - S ko:K07149 - ko00000 membrane
PGHHMJKG_03376 8.24e-146 sfp - - H ko:K06133 ko00770,map00770 ko00000,ko00001,ko01000 Belongs to the P-Pant transferase superfamily
PGHHMJKG_03377 0.0 ycxD - - K - - - GntR family transcriptional regulator
PGHHMJKG_03378 1.17e-198 ycxC - - EG - - - EamA-like transporter family
PGHHMJKG_03379 1.48e-122 - - - S - - - YcxB-like protein
PGHHMJKG_03380 4.92e-285 - - - EGP - - - Major Facilitator Superfamily
PGHHMJKG_03381 1.63e-179 srfAD - - Q ko:K15657 ko02024,map02024 ko00000,ko00001,ko01008 thioesterase
PGHHMJKG_03382 0.0 srfAC - - Q ko:K15656,ko:K16121 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 COG1020 Non-ribosomal peptide synthetase modules and related proteins
PGHHMJKG_03383 1.96e-302 srfAB - - Q ko:K15654,ko:K15655,ko:K16120 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHHMJKG_03384 7.57e-28 yxeD - - - - - - -
PGHHMJKG_03385 5.99e-41 yxeE - - - - - - -
PGHHMJKG_03388 3.29e-193 yxeH - - S - - - hydrolases of the HAD superfamily
PGHHMJKG_03389 4.03e-239 yxeI 3.5.1.24 - M ko:K01442 ko00120,ko00121,ko01100,map00120,map00121,map01100 ko00000,ko00001,ko01000 Linear amide C-N hydrolases, choloylglycine hydrolase family
PGHHMJKG_03390 0.0 yxeK - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGHHMJKG_03391 6.03e-119 yxeL - - K - - - COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_03392 4.3e-186 yxeM - - M ko:K16961 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PGHHMJKG_03393 3e-148 yxeN - - P ko:K10009,ko:K16962 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PGHHMJKG_03394 6.82e-171 yxeO - - P ko:K16960,ko:K16963 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_03395 4.78e-271 yxeP - - E ko:K21613 - ko00000,ko01000,ko01002 hydrolase activity
PGHHMJKG_03396 0.0 yxeQ - - S - - - MmgE/PrpD family
PGHHMJKG_03397 2.99e-249 eutH - - E ko:K04023 - ko00000 Ethanolamine utilisation protein, EutH
PGHHMJKG_03398 8.39e-194 - - - S - - - Domain of Unknown Function (DUF1206)
PGHHMJKG_03399 7.06e-221 deoR - - K ko:K05346 - ko00000,ko03000 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PGHHMJKG_03400 1.18e-149 deoC 4.1.2.4 - F ko:K01619 ko00030,map00030 ko00000,ko00001,ko01000 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PGHHMJKG_03401 1.92e-263 nupC - - F ko:K11535 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGHHMJKG_03402 8.11e-299 pdp 2.4.2.2 - F ko:K00756 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko01000 phosphorylase
PGHHMJKG_03403 2.24e-204 ybgF - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PGHHMJKG_03404 0.0 hutU 4.2.1.49 - E ko:K01712 ko00340,ko01100,map00340,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PGHHMJKG_03405 1.49e-308 yxiA 3.2.1.99 GH43 G ko:K06113 - ko00000,ko01000 Belongs to the glycosyl hydrolase 43 family
PGHHMJKG_03406 2.01e-193 - - - L - - - Protein of unknown function (DUF2726)
PGHHMJKG_03407 1.23e-78 mutT 3.6.1.55 - L ko:K03574 - ko00000,ko01000,ko03400 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PGHHMJKG_03408 0.0 - - - L - - - HKD family nuclease
PGHHMJKG_03409 5.38e-37 - - - S - - - Domain of unknown function (DUF5082)
PGHHMJKG_03410 1.33e-52 yxiC - - S - - - Family of unknown function (DUF5344)
PGHHMJKG_03411 0.0 - - - S ko:K21493 - ko00000,ko01000,ko02048 nuclease activity
PGHHMJKG_03412 5.35e-102 - - - S ko:K21494 - ko00000,ko02048 SMI1 / KNR4 family
PGHHMJKG_03413 1.56e-53 - - - - - - - -
PGHHMJKG_03414 8.86e-317 bglH 3.2.1.86 GT1 G ko:K01223 ko00010,ko00500,map00010,map00500 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 1 family
PGHHMJKG_03415 8.5e-95 yxiE - - T - - - Belongs to the universal stress protein A family
PGHHMJKG_03416 4.54e-157 - 1.14.11.45 - E ko:K20418 - ko00000,ko01000 2OG-Fe dioxygenase
PGHHMJKG_03417 1.36e-160 bacC 1.1.1.385 - IQ ko:K19548 ko01130,map01130 ko00000,ko00001,ko00002,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_03418 5.69e-208 yxxF - - EG - - - EamA-like transporter family
PGHHMJKG_03419 0.0 wapA - - M - - - COG3209 Rhs family protein
PGHHMJKG_03420 3.29e-19 yxiJ - - S - - - YxiJ-like protein
PGHHMJKG_03421 7.65e-83 yhfM - - - - - - -
PGHHMJKG_03422 9.64e-308 yhfN - - O - - - Peptidase M48
PGHHMJKG_03423 3.99e-259 aprE 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PGHHMJKG_03424 5.98e-100 - - - K - - - acetyltransferase
PGHHMJKG_03425 2.4e-232 yhfP 1.1.1.1 - C ko:K00001 ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220 ko00000,ko00001,ko01000 Quinone oxidoreductase
PGHHMJKG_03426 3.23e-222 yhfQ - - M ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Periplasmic binding protein
PGHHMJKG_03427 1.13e-53 - - - S - - - COG NOG14552 non supervised orthologous group
PGHHMJKG_03428 1.22e-136 acm2 3.2.1.17 - NU ko:K01185 - ko00000,ko01000 Prophage endopeptidase tail
PGHHMJKG_03430 0.0 - - - D - - - Phage tail tape measure protein
PGHHMJKG_03433 1.46e-33 - - - - - - - -
PGHHMJKG_03435 8.3e-40 - - - S - - - Bacteriophage HK97-gp10, putative tail-component
PGHHMJKG_03436 8.17e-38 - - - S - - - Phage head-tail joining protein
PGHHMJKG_03438 5.45e-13 - - - - - - - -
PGHHMJKG_03439 7.58e-162 - - - S - - - capsid protein
PGHHMJKG_03440 1.32e-92 - - - S ko:K06904 - ko00000 Caudovirus prohead serine protease
PGHHMJKG_03441 1.33e-216 - - - S - - - portal protein
PGHHMJKG_03443 1.19e-179 terL - - S - - - Terminase
PGHHMJKG_03444 3.93e-73 - - - L - - - Terminase, small subunit
PGHHMJKG_03450 2.17e-302 htrA 3.4.21.107 - O ko:K04771 ko01503,ko02020,map01503,map02020 ko00000,ko00001,ko00002,ko01000,ko01002,ko03110 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PGHHMJKG_03451 6.4e-164 cssR - - T ko:K07770 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_03452 9.22e-317 cssS 2.7.13.3 - T ko:K07650 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_03453 3.06e-204 yuxN - - K - - - Transcriptional regulator
PGHHMJKG_03454 0.0 fumC 4.2.1.2 - C ko:K01679 ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211 ko00000,ko00001,ko00002,ko01000 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PGHHMJKG_03455 1.06e-32 - - - S - - - Protein of unknown function (DUF3970)
PGHHMJKG_03456 0.0 gerAA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PGHHMJKG_03457 7.95e-251 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PGHHMJKG_03458 5.54e-234 gerAC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination B3/ GerAC like, C-terminal
PGHHMJKG_03459 8.64e-137 vraR - - KT ko:K07694,ko:K11618 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PGHHMJKG_03460 3.34e-245 vraS 2.7.13.3 - T ko:K07681,ko:K11617 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_03461 5.39e-164 - - - S ko:K11622 ko02020,map02020 ko00000,ko00001 Cell wall-active antibiotics response 4TMS YvqF
PGHHMJKG_03462 8.15e-172 liaG - - S ko:K11621 ko02020,map02020 ko00000,ko00001 Putative adhesin
PGHHMJKG_03463 2.85e-142 liaH - - KT ko:K03969,ko:K11620 ko02020,map02020 ko00000,ko00001,ko00002 COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PGHHMJKG_03464 1.07e-82 liaI - - S ko:K11619 ko02020,map02020 ko00000,ko00001,ko00002 membrane
PGHHMJKG_03465 1.53e-286 yvqJ - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_03466 5.32e-129 yvqK 2.5.1.17 - S ko:K00798 ko00860,ko01100,map00860,map01100 ko00000,ko00001,ko00002,ko01000 Adenosyltransferase
PGHHMJKG_03467 5.43e-311 yvrA 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PGHHMJKG_03468 7.73e-236 btuC - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03469 7.32e-219 btuF - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PGHHMJKG_03470 2.89e-179 yvrD - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_03471 3.79e-219 yvrE - - G ko:K14274 ko00040,map00040 ko00000,ko00001,ko01000 SMP-30/Gluconolaconase/LRE-like region
PGHHMJKG_03472 0.0 yvrG - - T - - - Histidine kinase
PGHHMJKG_03473 1.1e-170 yvrH - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_03474 5.07e-32 - - - - - - - -
PGHHMJKG_03475 1.12e-124 yvrI - - K ko:K03093 - ko00000,ko03021 RNA polymerase
PGHHMJKG_03476 3.46e-26 - - - S - - - YvrJ protein family
PGHHMJKG_03477 3.76e-291 oxdC 4.1.1.2 - G ko:K01569 ko00630,ko01100,map00630,map01100 ko00000,ko00001,ko01000 Oxalate decarboxylase
PGHHMJKG_03478 9.89e-86 yvrL - - S - - - Regulatory protein YrvL
PGHHMJKG_03479 2.21e-272 yvrN - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PGHHMJKG_03480 4.64e-159 yvrO - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_03481 3.44e-229 - - - M ko:K02005 - ko00000 Efflux transporter rnd family, mfp subunit
PGHHMJKG_03482 2.92e-191 fhuC 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PGHHMJKG_03483 4.78e-226 fhuG - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03484 4.04e-235 fhuB - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03485 2.57e-224 fhuD - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 ABC transporter
PGHHMJKG_03487 0.0 yvsH - - E ko:K03294,ko:K03758 - ko00000,ko02000 Arginine ornithine antiporter
PGHHMJKG_03488 9.37e-23 - - - S ko:K06427 - ko00000 Small spore protein J (Spore_SspJ)
PGHHMJKG_03489 2.38e-109 yvsG - - S ko:K07038 - ko00000 LexA-binding, inner membrane-associated putative hydrolase
PGHHMJKG_03490 0.0 yvgJ - - M ko:K01138 - ko00000,ko01000 Belongs to the LTA synthase family
PGHHMJKG_03491 2.97e-213 yvgK - - P ko:K07219 - ko00000 COG1910 Periplasmic molybdate-binding protein domain
PGHHMJKG_03492 2.11e-175 modA - - P ko:K02020 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG0725 ABC-type molybdate transport system, periplasmic component
PGHHMJKG_03493 1.01e-152 modB - - P ko:K02018 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4149 ABC-type molybdate transport system, permease component
PGHHMJKG_03494 6.19e-201 yvgN - - S - - - reductase
PGHHMJKG_03495 9.32e-112 yvgO - - - - - - -
PGHHMJKG_03496 0.0 yvgP - - P ko:K03316 - ko00000 COG0025 NhaP-type Na H and K H antiporters
PGHHMJKG_03497 0.0 cysI 1.8.1.2, 1.8.7.1 - P ko:K00381,ko:K00392 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PGHHMJKG_03498 0.0 cysJ 1.8.1.2 - P ko:K00380 ko00920,ko01100,ko01120,map00920,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PGHHMJKG_03499 0.0 helD 3.6.4.12 - L ko:K03657 ko03420,ko03430,map03420,map03430 ko00000,ko00001,ko01000,ko03400 DNA helicase
PGHHMJKG_03501 6.7e-139 yvgT - - S - - - membrane
PGHHMJKG_03502 1.99e-95 bdbC - - O ko:K03611 - ko00000,ko03110 Required for disulfide bond formation in some proteins
PGHHMJKG_03503 3.45e-137 bdbD - - O - - - Thioredoxin
PGHHMJKG_03504 0.0 cadA 3.6.3.3, 3.6.3.5 - P ko:K01534 - ko00000,ko01000 COG2217 Cation transport ATPase
PGHHMJKG_03505 1.36e-37 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGHHMJKG_03506 2.02e-48 dinB2 - - L ko:K03502 - ko00000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGHHMJKG_03507 4.84e-85 - - - S - - - damaged DNA binding
PGHHMJKG_03508 2.34e-14 - - - S - - - YolD-like protein
PGHHMJKG_03511 1.06e-127 - - - J - - - Acetyltransferase (GNAT) domain
PGHHMJKG_03512 7.01e-129 yokK - - S - - - SMI1 / KNR4 family
PGHHMJKG_03513 3.18e-101 - - - S - - - SMI1-KNR4 cell-wall
PGHHMJKG_03514 1.35e-111 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PGHHMJKG_03515 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PGHHMJKG_03516 2.8e-132 yokH - - G - - - SMI1 / KNR4 family
PGHHMJKG_03517 0.0 iaaM 1.4.3.4 - E ko:K00274 ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034 ko00000,ko00001,ko00002,ko01000 COG1231 Monoamine oxidase
PGHHMJKG_03518 9e-72 csaA - - J ko:K06878 - ko00000 tRNA-binding protein
PGHHMJKG_03519 5.45e-173 yobQ - - K - - - helix_turn_helix, arabinose operon control protein
PGHHMJKG_03520 2.81e-178 - - - J - - - FR47-like protein
PGHHMJKG_03521 6.23e-127 yobS - - K - - - Transcriptional regulator
PGHHMJKG_03522 1.29e-167 yobT - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PGHHMJKG_03523 4.8e-111 - - - K - - - Bacterial transcription activator, effector binding domain
PGHHMJKG_03524 1.73e-221 yobV - - K - - - WYL domain
PGHHMJKG_03525 7.38e-121 yobW - - - - - - -
PGHHMJKG_03526 8.12e-69 czrA - - K ko:K22043 - ko00000,ko03000 transcriptional
PGHHMJKG_03527 3.28e-157 yocA - - M - - - COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PGHHMJKG_03529 9.04e-156 ybbM - - S ko:K02069 - ko00000,ko00002,ko02000 transport system, permease component
PGHHMJKG_03530 2.79e-175 yjkB - - P ko:K02068 - ko00000,ko00002,ko02000 ATPases associated with a variety of cellular activities
PGHHMJKG_03531 8.95e-225 yjlA - - EG - - - Putative multidrug resistance efflux transporter
PGHHMJKG_03532 1.26e-20 yjlB - - S - - - Cupin domain
PGHHMJKG_03533 4.85e-54 yjlB - - S - - - Cupin domain
PGHHMJKG_03534 1.39e-87 yjlC - - S - - - Protein of unknown function (DUF1641)
PGHHMJKG_03535 2.15e-280 yjlD 1.6.99.3 - C ko:K03885 ko00190,map00190 ko00000,ko00001,ko01000 NADH dehydrogenase
PGHHMJKG_03536 0.0 uxaC 5.3.1.12 - G ko:K01812 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 glucuronate isomerase
PGHHMJKG_03537 1.13e-165 - - - G ko:K03292 - ko00000 symporter YjmB
PGHHMJKG_03538 8.14e-128 - - - G ko:K03292 - ko00000 symporter YjmB
PGHHMJKG_03539 1.03e-241 allD 1.1.1.350 - C ko:K00073 ko00230,ko01120,map00230,map01120 ko00000,ko00001,ko01000 Belongs to the LDH2 MDH2 oxidoreductase family
PGHHMJKG_03540 1.53e-244 yjmD 1.1.1.380 - E ko:K08322 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko01000 Alcohol dehydrogenase GroES-like domain
PGHHMJKG_03541 1.08e-270 uxuA 4.2.1.8 - G ko:K01686 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the dehydration of D-mannonate
PGHHMJKG_03542 1.83e-194 yjmF - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_03543 4.58e-288 exuT - - G ko:K03535,ko:K08191 - ko00000,ko02000 Sugar (and other) transporter
PGHHMJKG_03544 1.15e-236 exuR - - K ko:K02529 - ko00000,ko03000 transcriptional
PGHHMJKG_03545 0.0 uxaB 1.1.1.58 - G ko:K00041 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 tagaturonate reductase activity
PGHHMJKG_03546 0.0 uxaA 4.2.1.42, 4.2.1.7 - G ko:K01685,ko:K01708 ko00040,ko00053,ko01100,map00040,map00053,map01100 ko00000,ko00001,ko00002,ko01000 Altronate
PGHHMJKG_03547 4.56e-167 yjnA - - S ko:K07090 - ko00000 membrane transporter protein
PGHHMJKG_03548 0.0 ybxG - - E ko:K03293 - ko00000 COG1113 Gamma-aminobutyrate permease and related permeases
PGHHMJKG_03549 4.65e-276 ybdO - - S - - - Domain of unknown function (DUF4885)
PGHHMJKG_03550 1.49e-192 ybdN - - - - - - -
PGHHMJKG_03551 1.96e-178 ybdM 2.7.11.1 - KLT ko:K08884 - ko00000,ko01000,ko01001 Protein tyrosine kinase
PGHHMJKG_03553 2.05e-131 - - - T - - - His Kinase A (phospho-acceptor) domain
PGHHMJKG_03554 1.89e-70 - - - T - - - His Kinase A (phospho-acceptor) domain
PGHHMJKG_03555 1.55e-65 - - - T ko:K02483 - ko00000,ko02022 Transcriptional regulatory protein, C terminal
PGHHMJKG_03556 3.6e-80 ybcI - - S - - - Uncharacterized conserved protein (DUF2294)
PGHHMJKG_03557 5.59e-64 - - - - - - - -
PGHHMJKG_03558 1.34e-120 ybcF - - P - - - carbonic anhydrase
PGHHMJKG_03559 0.0 ybcC - - S ko:K09822 - ko00000 Belongs to the UPF0753 family
PGHHMJKG_03560 0.0 ndhF 1.6.5.3 - CP ko:K05577 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PGHHMJKG_03561 8.33e-58 - - - S - - - Metallo-beta-lactamase superfamily
PGHHMJKG_03562 1.98e-56 - - - S - - - MepB protein
PGHHMJKG_03563 0.0 - - - IQ ko:K15641,ko:K16398,ko:K16417,ko:K20788 ko01052,map01052 ko00000,ko00001,ko01008 PKS_KR
PGHHMJKG_03564 5.3e-49 bofA - - S ko:K06317 - ko00000 Sigma-K factor-processing regulatory protein BofA
PGHHMJKG_03565 1.55e-42 yaaL - - S - - - Protein of unknown function (DUF2508)
PGHHMJKG_03566 8.53e-142 recR - - L ko:K06187 ko03440,map03440 ko00000,ko00001,ko03400 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PGHHMJKG_03567 8.75e-55 yaaK - - S ko:K09747 - ko00000 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PGHHMJKG_03568 0.0 dnaX 2.7.7.7 - L ko:K02343 ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440 ko00000,ko00001,ko00002,ko01000,ko03032,ko03400 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PGHHMJKG_03569 1.05e-108 tadA 3.5.4.33 - FJ ko:K11991 - ko00000,ko01000,ko03016 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PGHHMJKG_03570 5.64e-125 yaaI - - Q - - - COG1335 Amidases related to nicotinamidase
PGHHMJKG_03571 7.55e-271 yaaH - - M ko:K06306 - ko00000 Glycoside Hydrolase Family
PGHHMJKG_03572 5.73e-149 dgk 2.7.1.113 - F ko:K15518 ko00230,map00230 ko00000,ko00001,ko01000 Deoxyguanosine kinase
PGHHMJKG_03573 3.72e-159 dck 2.7.1.74, 2.7.1.76 - F ko:K15519 ko00230,ko00240,ko01100,map00230,map00240,map01100 ko00000,ko00001,ko01000 Deoxycytidine kinase
PGHHMJKG_03575 4.64e-294 serS 6.1.1.11 - J ko:K01875 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PGHHMJKG_03576 5.55e-137 pdxT 4.3.3.6 - H ko:K08681 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PGHHMJKG_03577 3.7e-202 pdxS 4.3.3.6 - H ko:K06215 ko00750,map00750 ko00000,ko00001,ko01000 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PGHHMJKG_03578 3.75e-316 dacA 3.4.16.4 - M ko:K01286,ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PGHHMJKG_03579 0.0 guaB 1.1.1.205 - F ko:K00088 ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PGHHMJKG_03580 5.89e-230 yaaC - - S - - - YaaC-like Protein
PGHHMJKG_03583 8.64e-97 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGHHMJKG_03584 4.66e-41 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGHHMJKG_03585 3.12e-192 ypuA - - S - - - Secreted protein
PGHHMJKG_03586 0.0 lysA 4.1.1.20 - E ko:K01586 ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PGHHMJKG_03587 0.0 spoVAF - - EG ko:K06408 - ko00000 Stage V sporulation protein AF
PGHHMJKG_03588 1.85e-143 - - - S ko:K06407 - ko00000 stage V sporulation protein
PGHHMJKG_03589 2.15e-75 spoVAEB - - S ko:K06407 - ko00000 stage V sporulation protein
PGHHMJKG_03590 8.55e-246 spoVAD - - I ko:K06406 - ko00000 Stage V sporulation protein AD
PGHHMJKG_03591 6.71e-102 spoVAC - - S ko:K06405 - ko00000 stage V sporulation protein AC
PGHHMJKG_03592 5.43e-90 spoVAB - - S ko:K06404 - ko00000 Stage V sporulation protein AB
PGHHMJKG_03593 4.7e-143 spoVAA - - S ko:K06403 - ko00000 Stage V sporulation protein AA
PGHHMJKG_03594 1.18e-174 sigF - - K ko:K03091 - ko00000,ko03021 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PGHHMJKG_03595 6.78e-100 spoIIAB 2.7.11.1 - F ko:K06379 - ko00000,ko01000 Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PGHHMJKG_03596 1.98e-76 spoIIAA - - T ko:K06378 - ko00000 Belongs to the anti-sigma-factor antagonist family
PGHHMJKG_03597 8.27e-272 dacF 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PGHHMJKG_03598 1.39e-190 punA 2.4.2.1, 2.4.2.28 - F ko:K00772,ko:K03783 ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110 ko00000,ko00001,ko00002,ko01000 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PGHHMJKG_03599 3.77e-291 deoB 5.4.2.7 - G ko:K01839 ko00030,ko00230,map00030,map00230 ko00000,ko00001,ko01000 Phosphotransfer between the C1 and C5 carbon atoms of pentose
PGHHMJKG_03600 2.26e-213 xerD - - L ko:K04763 - ko00000,ko03036 recombinase XerD
PGHHMJKG_03601 2.73e-50 - - - S - - - Protein of unknown function (DUF4227)
PGHHMJKG_03602 2.26e-104 fur - - P ko:K03711 - ko00000,ko03000 Belongs to the Fur family
PGHHMJKG_03603 1.96e-139 spoIIM - - S ko:K06384 - ko00000 Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PGHHMJKG_03604 1.47e-41 yqkK - - - - - - -
PGHHMJKG_03605 3.95e-309 mleA 1.1.1.38 - C ko:K00027 ko00620,ko01200,ko02020,map00620,map01200,map02020 ko00000,ko00001,ko01000 malic enzyme
PGHHMJKG_03606 0.0 mleN - - C ko:K03315 - ko00000,ko02000 Na H antiporter
PGHHMJKG_03607 0.0 aspA 4.3.1.1 - E ko:K01744 ko00250,ko01100,map00250,map01100 ko00000,ko00001,ko01000 Aspartate ammonia-lyase
PGHHMJKG_03608 1.77e-238 ansA 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 L-asparaginase
PGHHMJKG_03609 3.18e-77 ansR - - K - - - Transcriptional regulator
PGHHMJKG_03610 1.45e-280 yqxK - - L - - - DNA helicase
PGHHMJKG_03611 4.07e-120 nudF 3.6.1.13 - L ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 Belongs to the Nudix hydrolase family
PGHHMJKG_03612 6.19e-09 - - - S - - - Protein of unknown function (DUF3936)
PGHHMJKG_03613 2.09e-214 yqkF - - C - - - oxidoreductases (related to aryl-alcohol dehydrogenases)
PGHHMJKG_03614 8.04e-27 yqkE - - S - - - Protein of unknown function (DUF3886)
PGHHMJKG_03615 4.61e-222 yqkD - - S ko:K06889 - ko00000 COG1073 Hydrolases of the alpha beta superfamily
PGHHMJKG_03616 1.12e-53 yqkC - - S - - - Protein of unknown function (DUF2552)
PGHHMJKG_03617 6.17e-73 yqkB - - S - - - Belongs to the HesB IscA family
PGHHMJKG_03618 3.23e-248 yqkA - - K - - - GrpB protein
PGHHMJKG_03619 1.52e-76 yqjZ - - S - - - enzyme involved in biosynthesis of extracellular polysaccharides
PGHHMJKG_03620 5.46e-113 yqjY - - K ko:K06977 - ko00000 acetyltransferase
PGHHMJKG_03621 1.87e-65 yqiX - - S - - - YolD-like protein
PGHHMJKG_03622 1.46e-304 polYB 2.7.7.7 - L ko:K02346,ko:K03502 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGHHMJKG_03624 4.23e-287 yqjV - - G - - - Major Facilitator Superfamily
PGHHMJKG_03626 2.21e-94 yqjT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHHMJKG_03627 2.69e-228 coaA 2.7.1.33 - F ko:K00867 ko00770,ko01100,map00770,map01100 ko00000,ko00001,ko00002,ko01000 Pantothenic acid kinase
PGHHMJKG_03628 0.0 dsdA 4.3.1.18 - E ko:K01753 ko00260,map00260 ko00000,ko00001,ko01000 Belongs to the serine threonine dehydratase family. DsdA subfamily
PGHHMJKG_03629 6.89e-185 yqjQ - - S ko:K07124 - ko00000 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_03630 1.56e-227 yqjP - - S - - - COG0491 Zn-dependent hydrolases, including glyoxylases
PGHHMJKG_03631 1.96e-189 proC 1.5.1.2 - E ko:K00286 ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PGHHMJKG_03632 2.21e-233 fni 5.3.3.2 - C ko:K01823 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PGHHMJKG_03633 7.8e-262 rpsA - - J ko:K02945 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Ribosomal protein S1
PGHHMJKG_03634 5.8e-146 cmk 2.7.4.25 - F ko:K00945 ko00240,ko01100,map00240,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the cytidylate kinase family. Type 1 subfamily
PGHHMJKG_03635 1.74e-32 - - - S - - - Family of unknown function (DUF5359)
PGHHMJKG_03636 2.02e-138 ypfA - - M - - - Flagellar protein YcgR
PGHHMJKG_03637 0.0 ypeB - - H ko:K06313 - ko00000 sporulation protein
PGHHMJKG_03638 1.99e-207 sleB 3.5.1.28 - M ko:K01449 - ko00000,ko01000 Spore cortex-lytic enzyme
PGHHMJKG_03639 1.76e-153 prsW - - S - - - Involved in the degradation of specific anti-sigma factors
PGHHMJKG_03640 2.51e-222 ypdA 1.8.1.9 - O ko:K00384 ko00450,map00450 ko00000,ko00001,ko01000 COG0492 Thioredoxin reductase
PGHHMJKG_03641 1.42e-308 gudB 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PGHHMJKG_03642 5.56e-136 mecB - - NOT ko:K16511 - ko00000 Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PGHHMJKG_03643 4.33e-188 ypbG - - S ko:K07098 - ko00000 Calcineurin-like phosphoesterase superfamily domain
PGHHMJKG_03644 4.08e-106 ypbF - - S - - - Protein of unknown function (DUF2663)
PGHHMJKG_03645 5.04e-148 ypbE - - M - - - Lysin motif
PGHHMJKG_03646 3.55e-128 ypbD - - S ko:K07052 - ko00000 metal-dependent membrane protease
PGHHMJKG_03647 0.0 recQ 3.6.4.12 - L ko:K03654 ko03018,map03018 ko00000,ko00001,ko01000,ko03400 DNA helicase
PGHHMJKG_03648 3.14e-255 ypbB 5.1.3.1 - S ko:K01783 ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 protein conserved in bacteria
PGHHMJKG_03649 8.35e-55 fer - - C ko:K05337 - ko00000 Ferredoxin
PGHHMJKG_03650 3.07e-122 ribU - - U - - - Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PGHHMJKG_03651 0.0 serA 1.1.1.399, 1.1.1.95 - E ko:K00058 ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PGHHMJKG_03652 9.27e-172 aroD 4.2.1.10 - E ko:K03785 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PGHHMJKG_03653 2.96e-135 rsiX - - - - - - -
PGHHMJKG_03654 8.11e-17 rsiX - - - - - - -
PGHHMJKG_03655 1.08e-133 sigX - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_03656 0.0 resE 2.7.13.3 - T ko:K07651 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_03657 1.69e-171 resD - - T ko:K07775 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_03658 1.56e-277 resC - - O - - - 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PGHHMJKG_03659 0.0 resB - - O ko:K07399 - ko00000 COG1333 ResB protein required for cytochrome c biosynthesis
PGHHMJKG_03660 8.71e-128 resA - - CO - - - Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PGHHMJKG_03661 4.45e-169 rluB 5.4.99.22 - J ko:K06178 - ko00000,ko01000,ko03009 Belongs to the pseudouridine synthase RsuA family
PGHHMJKG_03662 8.62e-114 spmB - - S ko:K06374 - ko00000 Spore maturation protein
PGHHMJKG_03663 7.57e-135 spmA - - S ko:K06373 - ko00000 Spore maturation protein
PGHHMJKG_03664 1.18e-272 dacB 3.4.16.4 - M ko:K07258 ko00550,ko01100,map00550,map01100 ko00000,ko00001,ko01000,ko01002,ko01011 Belongs to the peptidase S11 family
PGHHMJKG_03665 2.92e-126 ypuI - - S - - - Protein of unknown function (DUF3907)
PGHHMJKG_03666 9.54e-134 scpB - - D ko:K06024 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PGHHMJKG_03667 3.82e-167 scpA - - D ko:K05896 - ko00000,ko03036 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PGHHMJKG_03668 1.4e-117 ypuF - - S ko:K09763 - ko00000 Domain of unknown function (DUF309)
PGHHMJKG_03669 1.12e-83 ribT - - K ko:K02859 - ko00000 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PGHHMJKG_03670 8.41e-107 ribH 2.5.1.78 - H ko:K00794 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PGHHMJKG_03671 1.04e-290 ribBA 3.5.4.25, 4.1.99.12 - H ko:K14652 ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PGHHMJKG_03672 2.5e-147 ribE 2.5.1.9 - H ko:K00793 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Riboflavin synthase
PGHHMJKG_03673 3.42e-259 ribD 1.1.1.193, 3.5.4.26 - H ko:K11752 ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024 ko00000,ko00001,ko00002,ko01000 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PGHHMJKG_03674 5.98e-72 ypuD - - - - - - -
PGHHMJKG_03675 3.63e-120 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PGHHMJKG_03677 7.41e-45 ypzJ - - S ko:K07069 - ko00000 nucleic-acid-binding protein containing a Zn-ribbon domain
PGHHMJKG_03679 5.68e-58 ppiB 5.2.1.8 - O ko:K03768 - ko00000,ko01000,ko03110 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PGHHMJKG_03681 3.82e-37 - - - - - - - -
PGHHMJKG_03682 1.22e-29 - - - L ko:K01173 ko04210,map04210 ko00000,ko00001,ko03029 DNA/RNA non-specific endonuclease
PGHHMJKG_03684 8.16e-77 - - - O - - - Papain family cysteine protease
PGHHMJKG_03685 1.73e-13 - - - - - - - -
PGHHMJKG_03687 0.0 gerKA - - EG ko:K06295,ko:K06307 - ko00000 Spore germination protein
PGHHMJKG_03688 1.22e-289 gerKC - - S ko:K06297 - ko00000 spore germination
PGHHMJKG_03689 5.28e-244 gerKB - - F ko:K06296 - ko00000,ko02000 Spore germination protein
PGHHMJKG_03690 1.33e-152 yclH - - P ko:K02003 - ko00000,ko00002,ko02000 ABC transporter
PGHHMJKG_03691 5.23e-274 yclI - - V ko:K02004 - ko00000,ko00002,ko02000 ABC transporter (permease) YclI
PGHHMJKG_03692 2.09e-164 yclJ - - T ko:K02483 - ko00000,ko02022 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PGHHMJKG_03693 0.0 yclK - - T - - - HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PGHHMJKG_03694 7.71e-98 rapA1 - - S ko:K06359,ko:K06361 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PGHHMJKG_03696 7.93e-06 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PGHHMJKG_03697 0.0 lysC 2.7.2.4 - E ko:K00928 ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230 ko00000,ko00001,ko00002,ko01000 Belongs to the aspartokinase family
PGHHMJKG_03699 1.09e-205 yclN - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03700 3.16e-209 yclO - - P ko:K02015 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PGHHMJKG_03701 2.29e-175 yclP 3.6.3.34 - P ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_03702 4.69e-212 yclQ - - P ko:K02016 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG4607 ABC-type enterochelin transport system, periplasmic component
PGHHMJKG_03703 0.0 ycnB - - EGP - - - the major facilitator superfamily
PGHHMJKG_03704 5.87e-198 ycnC - - K - - - Transcriptional regulator
PGHHMJKG_03705 2.12e-174 - 1.5.1.39 - C ko:K10678,ko:K19286 ko00633,ko00740,ko01100,ko01120,map00633,map00740,map01100,map01120 ko00000,ko00001,ko01000 Oxidoreductase
PGHHMJKG_03706 1.68e-60 ycnE - - S - - - Monooxygenase
PGHHMJKG_03707 6.51e-69 yczG - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PGHHMJKG_03708 0.0 gabR - - K ko:K00375 - ko00000,ko03000 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PGHHMJKG_03709 3.26e-311 gabT 2.6.1.19, 2.6.1.22 - E ko:K00823,ko:K07250 ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120 ko00000,ko00001,ko00002,ko01000,ko01007 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PGHHMJKG_03710 0.0 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 - C ko:K00135 ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGHHMJKG_03711 1.67e-190 glcU - - U ko:K05340 - ko00000,ko02000 Glucose uptake
PGHHMJKG_03712 3.27e-184 gdh 1.1.1.47 - IQ ko:K00034 ko00030,ko01120,ko01200,map00030,map01120,map01200 ko00000,ko00001,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_03713 1.34e-132 ycnI - - S - - - protein conserved in bacteria
PGHHMJKG_03714 0.0 ycnJ - - P ko:K14166 - ko00000,ko02000 protein, homolog of Cu resistance protein CopC
PGHHMJKG_03715 2.03e-136 ycnK - - K ko:K21601 - ko00000,ko03000 COG1349 Transcriptional regulators of sugar metabolism
PGHHMJKG_03716 1.34e-74 - - - - - - - -
PGHHMJKG_03717 0.0 mtlA 2.7.1.197 - G ko:K02799,ko:K02800 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG2213 Phosphotransferase system, mannitol-specific IIBC component
PGHHMJKG_03718 8.3e-95 mtlF 2.7.1.197 - G ko:K02798 ko00051,ko02060,map00051,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PGHHMJKG_03719 1.41e-264 mtlD 1.1.1.17 - G ko:K00009 ko00051,map00051 ko00000,ko00001,ko01000 COG0246 Mannitol-1-phosphate altronate dehydrogenases
PGHHMJKG_03720 1.01e-256 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 - CE ko:K07246 ko00630,ko00650,map00630,map00650 ko00000,ko00001,ko01000 Tartrate dehydrogenase
PGHHMJKG_03722 1.25e-96 lepB 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PGHHMJKG_03723 1.32e-24 - - - Q - - - COG0412 Dienelactone hydrolase and related enzymes
PGHHMJKG_03724 2.68e-87 ycsD 4.2.1.59 - I ko:K02372 ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 FabA-like domain
PGHHMJKG_03730 2.54e-53 nucA - - M - - - Deoxyribonuclease NucA/NucB
PGHHMJKG_03731 2.52e-149 ywaC 2.7.6.5 - S ko:K00951,ko:K07816 ko00230,map00230 ko00000,ko00001,ko01000 protein conserved in bacteria
PGHHMJKG_03732 0.0 ywaD 3.4.11.10, 3.4.11.6 - S ko:K19701 - ko00000,ko01000,ko01002 PA domain
PGHHMJKG_03733 1.28e-296 tyrS 6.1.1.1 - J ko:K01866 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PGHHMJKG_03734 1.25e-114 ywaE - - K - - - Transcriptional regulator
PGHHMJKG_03735 3.49e-158 ywaF - - S - - - Integral membrane protein
PGHHMJKG_03736 5.37e-216 gspA - - M - - - General stress
PGHHMJKG_03737 2.6e-195 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PGHHMJKG_03738 4.43e-307 sacX 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_03739 0.0 epr 3.4.21.62 - O ko:K01342,ko:K13277 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PGHHMJKG_03740 1.81e-311 licC - - G ko:K02761 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko02000 The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PGHHMJKG_03741 2.61e-163 ywbB - - S - - - Protein of unknown function (DUF2711)
PGHHMJKG_03742 8.1e-87 ywbC 4.4.1.5 - E ko:K01759 ko00620,map00620 ko00000,ko00001,ko01000 glyoxalase
PGHHMJKG_03743 1.28e-276 ywbD 2.1.1.191 - J ko:K06969 - ko00000,ko01000,ko03009 Methyltransferase
PGHHMJKG_03744 1.05e-36 ywbE - - S - - - Uncharacterized conserved protein (DUF2196)
PGHHMJKG_03745 7.14e-276 ywbF - - EGP ko:K05820 - ko00000,ko02000 Nucleoside H+ symporter
PGHHMJKG_03746 1.21e-143 ywbG - - M - - - effector of murein hydrolase
PGHHMJKG_03747 4.47e-76 ywbH - - S ko:K06518 - ko00000,ko02000 Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PGHHMJKG_03748 1.28e-201 ywbI - - K - - - Transcriptional regulator
PGHHMJKG_03749 5.39e-184 thiM 2.7.1.50 - H ko:K00878 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PGHHMJKG_03750 3e-147 thiE 2.5.1.3 - H ko:K00788 ko00730,ko01100,map00730,map01100 ko00000,ko00001,ko00002,ko01000 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PGHHMJKG_03751 5.68e-314 - - - P ko:K07243 - ko00000,ko02000 COG0672 High-affinity Fe2 Pb2 permease
PGHHMJKG_03752 2.42e-246 ycdO - - P ko:K07224 - ko00000,ko02000 periplasmic lipoprotein involved in iron transport
PGHHMJKG_03753 2.54e-307 ywbN - - P ko:K07223,ko:K16301 - ko00000,ko01000,ko02000 Dyp-type peroxidase family protein
PGHHMJKG_03754 1.47e-143 ywbO - - Q - - - dithiol-disulfide isomerase involved in polyketide biosynthesis
PGHHMJKG_03755 0.0 ywcA - - S ko:K14393 - ko00000,ko02000 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PGHHMJKG_03756 1.23e-63 ywcB - - S - - - Protein of unknown function, DUF485
PGHHMJKG_03758 1.98e-157 ywcC - - K - - - transcriptional regulator
PGHHMJKG_03759 3.33e-77 gtcA - - S - - - GtrA-like protein
PGHHMJKG_03760 5.34e-289 galK 2.7.1.6 - G ko:K00849 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PGHHMJKG_03761 0.0 galT 2.7.7.12 - G ko:K00965 ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917 ko00000,ko00001,ko00002,ko01000 UDP-glucose--hexose-1-phosphate uridylyltransferase
PGHHMJKG_03762 5.11e-49 ydaS - - S - - - membrane
PGHHMJKG_03763 6.94e-226 qoxA 1.10.3.12 - C ko:K02826 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PGHHMJKG_03764 0.0 qoxB 1.10.3.12 - C ko:K02827 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PGHHMJKG_03765 1.2e-144 qoxC 1.10.3.12 - C ko:K02828 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PGHHMJKG_03766 1.3e-82 qoxD 1.10.3.12 - C ko:K02829 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 quinol oxidase, subunit
PGHHMJKG_03767 6.61e-52 ywcE - - S - - - Required for proper spore morphogenesis. Important for spore germination
PGHHMJKG_03769 2.19e-174 rodA - - D ko:K05837 - ko00000,ko03036 Belongs to the SEDS family
PGHHMJKG_03770 1.9e-177 nfrA1 1.5.1.38 - C ko:K19285 ko00740,ko01100,map00740,map01100 ko00000,ko00001,ko01000 Oxidoreductase
PGHHMJKG_03771 2.6e-233 ywcH - - C - - - COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PGHHMJKG_03772 0.0 prtS 3.4.21.110, 3.4.21.96 - O ko:K01361,ko:K08652,ko:K14647 ko02024,map02024 ko00000,ko00001,ko01000,ko01002,ko03110 Belongs to the peptidase S8 family
PGHHMJKG_03774 3.69e-193 sacT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PGHHMJKG_03775 8e-178 - - - P ko:K02598 - ko00000,ko02000 Formate/nitrite transporter
PGHHMJKG_03776 0.0 sacP 2.7.1.211 - G ko:K02809,ko:K02810 ko00500,ko02060,map00500,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_03777 0.0 sacA 3.2.1.26 GH32 G ko:K01193 ko00052,ko00500,ko01100,map00052,map00500,map01100 ko00000,ko00001,ko01000 invertase
PGHHMJKG_03778 6.19e-39 ywdA - - - - - - -
PGHHMJKG_03779 5.2e-186 pdxK 2.7.1.35, 2.7.1.49, 2.7.4.7 - H ko:K00868,ko:K00941 ko00730,ko00750,ko01100,map00730,map00750,map01100 ko00000,ko00001,ko00002,ko01000 Phosphomethylpyrimidine kinase
PGHHMJKG_03780 4.68e-192 ywdF - - S - - - Glycosyltransferase like family 2
PGHHMJKG_03781 2.32e-166 ung 3.2.2.27 - L ko:K03648 ko03410,ko05340,map03410,map05340 ko00000,ko00001,ko01000,ko03400 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PGHHMJKG_03782 0.0 ywdH 1.2.1.3 - C ko:K00128 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the aldehyde dehydrogenase family
PGHHMJKG_03783 1.26e-62 ywdI - - S - - - Family of unknown function (DUF5327)
PGHHMJKG_03784 1.86e-303 ywdJ - - F - - - Xanthine uracil
PGHHMJKG_03785 1.59e-78 ywdK - - S - - - small membrane protein
PGHHMJKG_03786 3.7e-106 gerQ - - S ko:K06305 - ko00000 Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PGHHMJKG_03787 8.08e-187 spsA - - M - - - Spore Coat
PGHHMJKG_03788 0.0 spsB - - M - - - Capsule polysaccharide biosynthesis protein
PGHHMJKG_03789 3.06e-283 spsC 2.6.1.102 - E ko:K13010 ko00520,map00520 ko00000,ko00001,ko01000,ko01005,ko01007 Belongs to the DegT DnrJ EryC1 family
PGHHMJKG_03790 2.01e-208 spsD 2.3.1.210 - K ko:K16704 - ko00000,ko01000 Spore Coat
PGHHMJKG_03791 7.93e-271 pseI 2.5.1.56, 2.5.1.97 - M ko:K01654,ko:K15898 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 acid synthase
PGHHMJKG_03792 2.47e-164 spsF - - M ko:K07257 - ko00000 Spore Coat
PGHHMJKG_03793 4.71e-239 spsG - - M - - - Spore Coat
PGHHMJKG_03794 6.13e-177 spsI 2.7.7.24 - M ko:K00973 ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PGHHMJKG_03795 9.08e-234 spsJ 4.2.1.46 - M ko:K01710 ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PGHHMJKG_03796 2.34e-204 rfbD 1.1.1.133 - M ko:K00067 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PGHHMJKG_03797 1.52e-112 spsL 5.1.3.13 - M ko:K01790 ko00521,ko00523,ko01130,map00521,map00523,map01130 ko00000,ko00001,ko00002,ko01000 Spore Coat
PGHHMJKG_03798 3.7e-101 - - - - - - - -
PGHHMJKG_03799 5.19e-311 rocG 1.4.1.2 - E ko:K00260 ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PGHHMJKG_03800 0.0 rocA 1.2.1.88 - C ko:K00294 ko00250,ko00330,ko01100,map00250,map00330,map01100 ko00000,ko00001,ko01000 Belongs to the aldehyde dehydrogenase family. RocA subfamily
PGHHMJKG_03801 0.0 rocB - - E - - - arginine degradation protein
PGHHMJKG_03802 0.0 rocC - - E ko:K02205,ko:K16235,ko:K16236 - ko00000,ko02000 amino acid
PGHHMJKG_03803 3.81e-275 ywfA - - EGP - - - -transporter
PGHHMJKG_03804 3.21e-305 - - - L - - - COG3328 Transposase and inactivated derivatives
PGHHMJKG_03805 9.05e-207 czcD - - P ko:K16264 - ko00000,ko02000 COG1230 Co Zn Cd efflux system component
PGHHMJKG_03806 1.23e-253 trkA - - P ko:K07222 - ko00000 Oxidoreductase
PGHHMJKG_03807 1.4e-203 - - - K - - - Transcriptional regulator
PGHHMJKG_03808 3.17e-212 yrdR - - EG - - - EamA-like transporter family
PGHHMJKG_03809 2.45e-23 - - - S - - - YrzO-like protein
PGHHMJKG_03810 1.02e-297 yrkA - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PGHHMJKG_03811 2.43e-264 mnaA 5.1.3.14 - M ko:K01791 ko00520,ko01100,ko05111,map00520,map01100,map05111 ko00000,ko00001,ko00002,ko01000,ko01005 Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PGHHMJKG_03812 1.64e-204 gtaB 2.7.7.9 - M ko:K00963 ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130 ko00000,ko00001,ko00002,ko01000 UTP-glucose-1-phosphate uridylyltransferase
PGHHMJKG_03813 1.07e-14 - - - L - - - COG2963 Transposase and inactivated derivatives
PGHHMJKG_03814 2.7e-204 tagH 3.6.3.40 - GM ko:K09693 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PGHHMJKG_03815 3.02e-171 tagG - - GM ko:K09692 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Transport permease protein
PGHHMJKG_03817 0.0 tagF2 2.7.8.12 - M ko:K09809 - ko00000,ko01000 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PGHHMJKG_03818 0.0 tagF 2.7.8.12 - M ko:K09809 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PGHHMJKG_03819 2.4e-90 tagD 2.7.7.39 - IM ko:K00980 ko00564,map00564 ko00000,ko00001,ko01000 Cytidylyltransferase
PGHHMJKG_03820 4.13e-182 tagA 2.4.1.187 GT26 M ko:K05946 ko05111,map05111 ko00000,ko00001,ko01000,ko01003 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PGHHMJKG_03821 1.5e-257 tagB 2.7.8.44 - M ko:K21285 - ko00000,ko01000 glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PGHHMJKG_03822 0.0 lytD 3.2.1.96 - G ko:K01227 ko00511,map00511 ko00000,ko00001,ko01000 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PGHHMJKG_03823 1.3e-238 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PGHHMJKG_03824 1.05e-250 gerBA - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PGHHMJKG_03825 6.06e-61 gerAB - - E ko:K06289,ko:K06292 - ko00000,ko02000 Spore germination protein
PGHHMJKG_03826 7.75e-258 gerBC - - S ko:K06290,ko:K06293,ko:K06312 - ko00000 Spore germination protein
PGHHMJKG_03827 8.52e-260 ywtG - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGHHMJKG_03828 3.53e-178 ywtF_2 - - K - - - Transcriptional regulator
PGHHMJKG_03829 1.99e-202 ywtE 3.1.3.104 - S ko:K21064 ko00740,ko01100,ko01110,map00740,map01100,map01110 ko00000,ko00001,ko00002,ko01000 hydrolases of the HAD superfamily
PGHHMJKG_03830 3.19e-304 pgdS - - M - - - COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PGHHMJKG_03832 9.36e-65 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PGHHMJKG_03833 1.82e-181 yndD1 - - EG ko:K06288,ko:K06291,ko:K06310 - ko00000 Spore germination protein
PGHHMJKG_03834 5.45e-112 - - - S ko:K06293,ko:K06312 - ko00000 Spore germination protein
PGHHMJKG_03835 2.52e-196 yndG - - S - - - DoxX-like family
PGHHMJKG_03836 2.87e-147 - - - S - - - Domain of unknown function (DUF4166)
PGHHMJKG_03837 0.0 yndJ - - S - - - YndJ-like protein
PGHHMJKG_03840 6.31e-173 yndL - - S - - - Replication protein
PGHHMJKG_03841 3.11e-95 yndM - - S - - - Protein of unknown function (DUF2512)
PGHHMJKG_03842 5.34e-97 fosB - - H ko:K11210,ko:K21252 - ko00000,ko01000,ko01504 Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PGHHMJKG_03843 7.22e-142 lexA 3.4.21.88 - K ko:K01356 - ko00000,ko00002,ko01000,ko01002,ko03400 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PGHHMJKG_03844 8.5e-65 yneA - - D - - - Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PGHHMJKG_03845 5.4e-143 yneB - - L - - - resolvase
PGHHMJKG_03846 1.15e-43 ynzC - - S - - - UPF0291 protein
PGHHMJKG_03847 0.0 tkt 2.2.1.1 - G ko:K00615 ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PGHHMJKG_03848 2.18e-106 yneE - - S - - - Sporulation inhibitor of replication protein sirA
PGHHMJKG_03849 4.36e-39 yneF - - S ko:K09976 - ko00000 UPF0154 protein
PGHHMJKG_03850 4.59e-21 ynzD - - S - - - Spo0E like sporulation regulatory protein
PGHHMJKG_03851 4.13e-165 ccdA - - O ko:K06196 - ko00000,ko02000 cytochrome c biogenesis protein
PGHHMJKG_03852 7.38e-78 ccdB - - T ko:K03413 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 cheY-homologous receiver domain
PGHHMJKG_03853 2.51e-98 yneJ - - O - - - COG4846 Membrane protein involved in cytochrome C biogenesis
PGHHMJKG_03854 1.46e-50 yqgY - - S - - - Protein of unknown function (DUF2626)
PGHHMJKG_03855 7.79e-85 yqgZ 1.20.4.1 - P ko:K00537,ko:K16509 - ko00000,ko01000 Belongs to the ArsC family
PGHHMJKG_03857 4.82e-190 yqhA - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PGHHMJKG_03858 2.01e-305 yqhB - - S - - - COG1253 Hemolysins and related proteins containing CBS domains
PGHHMJKG_03859 8.73e-233 yqxL - - P - - - Mg2 transporter protein
PGHHMJKG_03860 3.73e-09 yhcV - - S - - - COG0517 FOG CBS domain
PGHHMJKG_03861 9.05e-257 comGA - - NU ko:K02243 - ko00000,ko00002,ko02044 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PGHHMJKG_03862 7.16e-218 comGB - - NU ko:K02244 - ko00000,ko00002,ko02044 COG1459 Type II secretory pathway, component PulF
PGHHMJKG_03863 5.33e-63 comGC - - U ko:K02245 - ko00000,ko00002,ko02044 Required for transformation and DNA binding
PGHHMJKG_03864 1.13e-92 gspH - - NU ko:K02246,ko:K02457,ko:K02459,ko:K02672,ko:K08084,ko:K10926 ko03070,ko05111,map03070,map05111 ko00000,ko00001,ko00002,ko02035,ko02044 protein transport across the cell outer membrane
PGHHMJKG_03865 3.45e-76 comGE - - - ko:K02247 - ko00000,ko00002,ko02044 -
PGHHMJKG_03866 4.1e-60 comGF - - U ko:K02246,ko:K02248 - ko00000,ko00002,ko02044 Putative Competence protein ComGF
PGHHMJKG_03867 3.78e-57 - - - S ko:K02249 - ko00000,ko00002,ko02044 ComG operon protein 7
PGHHMJKG_03868 2.84e-36 yqzE - - S - - - YqzE-like protein
PGHHMJKG_03869 6.36e-71 yqzG - - S - - - Protein of unknown function (DUF3889)
PGHHMJKG_03870 9.33e-155 yqxM - - - ko:K19433 - ko00000 -
PGHHMJKG_03871 4.27e-97 sipW 3.4.21.89 - U ko:K13280 ko03060,map03060 ko00000,ko00001,ko01000,ko01002 Signal peptidase
PGHHMJKG_03872 3.67e-181 tasA_1 - - S ko:K06336 - ko00000,ko01002 Cell division protein FtsN
PGHHMJKG_03873 3.69e-72 sinR - - K ko:K19449 - ko00000,ko03000 transcriptional
PGHHMJKG_03874 4.84e-34 sinI - - S ko:K06372 - ko00000 Anti-repressor SinI
PGHHMJKG_03875 1.52e-195 yqhG - - S - - - Bacterial protein YqhG of unknown function
PGHHMJKG_03876 0.0 yqhH - - L - - - COG0553 Superfamily II DNA RNA helicases, SNF2 family
PGHHMJKG_03877 7.79e-261 gcvT 2.1.2.10 - E ko:K00605 ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002,ko01000 The glycine cleavage system catalyzes the degradation of glycine
PGHHMJKG_03878 0.0 gcvPA 1.4.4.2 - E ko:K00282 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PGHHMJKG_03879 0.0 gcvPB 1.4.4.2 - E ko:K00283 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko01000 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PGHHMJKG_03880 2.51e-81 yqhL - - P - - - COG0607 Rhodanese-related sulfurtransferase
PGHHMJKG_03881 2.63e-203 lipM 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PGHHMJKG_03882 1.97e-97 mntR - - K ko:K03709 - ko00000,ko03000 Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PGHHMJKG_03883 1.41e-209 yqhO - - S ko:K07001 - ko00000 esterase of the alpha-beta hydrolase superfamily
PGHHMJKG_03884 5.18e-81 yqhP - - - - - - -
PGHHMJKG_03885 1.48e-220 yqhQ - - S - - - Protein of unknown function (DUF1385)
PGHHMJKG_03886 8.02e-121 yqhR - - S - - - Conserved membrane protein YqhR
PGHHMJKG_03887 1.17e-101 aroQ 4.2.1.10 - E ko:K03786 ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a trans-dehydration via an enolate intermediate
PGHHMJKG_03888 3.65e-250 yqhT 3.4.11.9, 3.4.13.9 - E ko:K01262,ko:K01271 - ko00000,ko01000,ko01002 COG0006 Xaa-Pro aminopeptidase
PGHHMJKG_03889 4.8e-128 efp - - J ko:K02356 - ko00000,ko03012 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PGHHMJKG_03890 6.96e-50 yqhV - - S - - - Protein of unknown function (DUF2619)
PGHHMJKG_03891 1.22e-218 spoIIIAA - - S ko:K06390 - ko00000 stage III sporulation protein AA
PGHHMJKG_03892 3.29e-110 spoIIIAB - - S ko:K06391 - ko00000 Stage III sporulation protein
PGHHMJKG_03893 1.63e-39 spoIIIAC - - S ko:K06392 - ko00000 stage III sporulation protein AC
PGHHMJKG_03894 1.93e-77 spoIIIAD - - S ko:K06393 - ko00000 Stage III sporulation protein AD
PGHHMJKG_03895 3.11e-256 spoIIIAE - - S ko:K06394 - ko00000 stage III sporulation protein AE
PGHHMJKG_03896 1.28e-131 spoIIIAF - - S ko:K06395 - ko00000 Stage III sporulation protein AF (Spore_III_AF)
PGHHMJKG_03897 7.6e-149 spoIIIAG - - S ko:K06396 - ko00000 stage III sporulation protein AG
PGHHMJKG_03898 9.92e-135 spoIIIAH - - S ko:K06397 - ko00000 SpoIIIAH-like protein
PGHHMJKG_03899 3.21e-93 accB - - I ko:K02160 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PGHHMJKG_03900 0.0 accC 6.3.4.14, 6.4.1.2 - I ko:K01961 ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212 ko00000,ko00001,ko00002,ko01000 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PGHHMJKG_03901 9.55e-88 yqhY - - S - - - protein conserved in bacteria
PGHHMJKG_03902 4.8e-86 nusB - - K ko:K03625 - ko00000,ko03009,ko03021 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PGHHMJKG_03903 1.24e-199 folD 1.5.1.5, 3.5.4.9 - F ko:K01491 ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PGHHMJKG_03904 1.02e-311 xseA 3.1.11.6 - L ko:K03601 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGHHMJKG_03905 1.09e-51 xseB 3.1.11.6 - L ko:K03602 ko03430,map03430 ko00000,ko00001,ko01000,ko03400 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PGHHMJKG_03906 4.2e-209 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29 - H ko:K13789 ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000,ko01006 Belongs to the FPP GGPP synthase family
PGHHMJKG_03907 0.0 dxs 2.2.1.7 - H ko:K01662 ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PGHHMJKG_03908 2.51e-198 rrmJ 2.1.1.226, 2.1.1.227 - J ko:K06442 - ko00000,ko01000,ko03009 rRNA methylase
PGHHMJKG_03909 3.75e-103 argR - - K ko:K03402 - ko00000,ko03000 Regulates arginine biosynthesis genes
PGHHMJKG_03910 0.0 recN - - L ko:K03631 - ko00000,ko03400 May be involved in recombinational repair of damaged DNA
PGHHMJKG_03911 2.54e-303 spoIVB 3.4.21.116 - M ko:K06399 - ko00000,ko01000,ko01002 Stage IV sporulation protein B
PGHHMJKG_03912 1.89e-186 spo0A - - KT ko:K07699 ko02020,ko02024,map02020,map02024 ko00000,ko00001,ko00002,ko02022 May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PGHHMJKG_03914 1.15e-272 yqiG - - C - - - COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PGHHMJKG_03915 4.74e-37 - - - - - - - -
PGHHMJKG_03916 5.67e-139 lytC_1 3.5.1.28 - M ko:K01448 ko01503,map01503 ko00000,ko00001,ko00002,ko01000,ko01011,ko03036 Cell wall hydrolase autolysin
PGHHMJKG_03917 7.42e-172 yqiK 3.1.4.46 - C ko:K01126 ko00564,map00564 ko00000,ko00001,ko01000 glycerophosphoryl diester phosphodiesterase
PGHHMJKG_03918 2.59e-277 mmgA 2.3.1.9 - I ko:K00626 ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020 ko00000,ko00001,ko00002,ko01000,ko04147 Belongs to the thiolase family
PGHHMJKG_03919 1.19e-199 mmgB 1.1.1.157 - I ko:K00074 ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120 ko00000,ko00001,ko01000 Dehydrogenase
PGHHMJKG_03920 2.01e-267 mmgC - - I ko:K18244 - ko00000,ko01000 acyl-CoA dehydrogenase
PGHHMJKG_03921 3.9e-266 mmgD 2.3.3.1 - C ko:K01647 ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230 br01601,ko00000,ko00001,ko00002,ko01000 Belongs to the citrate synthase family
PGHHMJKG_03922 0.0 prpD 4.2.1.79 - S ko:K01720 ko00640,map00640 ko00000,ko00001,ko01000 2-methylcitrate dehydratase
PGHHMJKG_03923 7.23e-208 prpB 4.1.3.30, 5.4.2.9 - G ko:K01841,ko:K03417 ko00440,ko00640,ko01100,ko01120,ko01130,map00440,map00640,map01100,map01120,map01130 ko00000,ko00001,ko01000 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PGHHMJKG_03924 1.56e-46 yqzF - - S - - - Protein of unknown function (DUF2627)
PGHHMJKG_03925 0.0 bkdR - - KT - - - Transcriptional regulator
PGHHMJKG_03926 1.18e-196 ptb 2.3.1.19 - C ko:K00634 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 phosphate butyryltransferase
PGHHMJKG_03927 1.92e-262 ldh 1.4.1.9 - E ko:K00263 ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130 ko00000,ko00001,ko01000 Belongs to the Glu Leu Phe Val dehydrogenases family
PGHHMJKG_03928 3.39e-255 buk 2.7.2.7 - C ko:K00929 ko00650,ko01100,map00650,map01100 ko00000,ko00001,ko01000 Belongs to the acetokinase family
PGHHMJKG_03929 0.0 bfmBC 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PGHHMJKG_03930 1.11e-237 bfmBAA 1.2.4.4 - C ko:K00166 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PGHHMJKG_03931 6.92e-235 bfmBAB 1.2.4.4 - C ko:K00167,ko:K21417 ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGHHMJKG_03932 3.77e-288 bkdB 2.3.1.12, 2.3.1.168 - C ko:K00627,ko:K09699 ko00010,ko00020,ko00280,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00280,map00620,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGHHMJKG_03933 4.31e-193 - - - K ko:K19575 - ko00000,ko00002,ko03000 helix_turn_helix, mercury resistance
PGHHMJKG_03934 1.79e-266 norA - - EGP ko:K08153,ko:K19576,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_03935 4.23e-214 bmrU - - I - - - COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PGHHMJKG_03936 3.79e-101 yqiW - - S - - - Belongs to the UPF0403 family
PGHHMJKG_03937 1.18e-174 artP - - ET ko:K02030 - ko00000,ko00002,ko02000 Belongs to the bacterial solute-binding protein 3 family
PGHHMJKG_03938 8.94e-143 artQ - - E ko:K02029 - ko00000,ko00002,ko02000 COG0765 ABC-type amino acid transport system, permease component
PGHHMJKG_03939 1.49e-165 artM 3.6.3.21 - E ko:K02028 - ko00000,ko00002,ko01000,ko02000 COG1126 ABC-type polar amino acid transport system, ATPase component
PGHHMJKG_03940 1.73e-221 yqjA - - S - - - Putative aromatic acid exporter C-terminal domain
PGHHMJKG_03941 9.84e-128 yqjB - - S - - - protein conserved in bacteria
PGHHMJKG_03943 5.45e-94 mce 5.1.99.1 - E ko:K05606 ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200 ko00000,ko00001,ko00002,ko01000 COG0346 Lactoylglutathione lyase and related lyases
PGHHMJKG_03944 0.0 yqjD 2.1.3.15, 6.4.1.3 - I ko:K01966 ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PGHHMJKG_03945 5.26e-259 yqjE 3.4.11.14, 3.4.11.4 - E ko:K01258,ko:K01263 - ko00000,ko01000,ko01002 COG2195 Di- and tripeptidases
PGHHMJKG_03946 1.57e-177 yqjF - - S ko:K09166 - ko00000 Uncharacterized conserved protein (COG2071)
PGHHMJKG_03947 1.47e-178 yidC - - U ko:K03217 ko02024,ko03060,ko03070,map02024,map03060,map03070 ko00000,ko00001,ko00002,ko02044,ko03029 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PGHHMJKG_03948 4.35e-32 yqzJ - - - - - - -
PGHHMJKG_03949 1.06e-298 dinB 2.7.7.7 - L ko:K02346 - ko00000,ko01000,ko03400 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PGHHMJKG_03950 0.0 gnd 1.1.1.343, 1.1.1.44 - G ko:K00033 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PGHHMJKG_03951 0.0 zwf 1.1.1.363, 1.1.1.49 - G ko:K00036 ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230 ko00000,ko00001,ko00002,ko01000,ko04147 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PGHHMJKG_03952 2.2e-221 rnz 3.1.26.11 - S ko:K00784 ko03013,map03013 ko00000,ko00001,ko01000,ko03016 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PGHHMJKG_03953 8.59e-27 rpmG - - J ko:K02913 ko03010,map03010 br01610,ko00000,ko00001,ko00002,ko03011 Belongs to the bacterial ribosomal protein bL33 family
PGHHMJKG_03954 3.17e-187 yqjL - - S - - - hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PGHHMJKG_03955 1.21e-245 namA 1.6.99.1 - C ko:K00354 - ko00000,ko01000 Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PGHHMJKG_03956 0.0 rocB - - E - - - arginine degradation protein
PGHHMJKG_03958 0.0 speA 4.1.1.17, 4.1.1.19 - E ko:K01581,ko:K01585 ko00330,ko00480,ko01100,ko01110,ko01130,map00330,map00480,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Arginine
PGHHMJKG_03959 6.37e-55 yktA - - S - - - Belongs to the UPF0223 family
PGHHMJKG_03960 2.15e-151 yktB - - S - - - Belongs to the UPF0637 family
PGHHMJKG_03961 4.48e-35 ykzI - - - - - - -
PGHHMJKG_03962 2.61e-192 suhB 3.1.3.25 - G ko:K01092 ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070 ko00000,ko00001,ko00002,ko01000 Inositol monophosphatase
PGHHMJKG_03963 1.17e-97 ykzC - - S - - - Acetyltransferase (GNAT) family
PGHHMJKG_03964 1.01e-220 - - - Q - - - Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PGHHMJKG_03965 0.0 mpl 3.4.24.28, 3.4.24.29 - E ko:K01400,ko:K01401,ko:K19351 ko01503,ko05150,map01503,map05150 ko00000,ko00001,ko01000,ko01002 Peptidase M4
PGHHMJKG_03966 0.0 ylaA - - - - - - -
PGHHMJKG_03967 1.44e-56 ylaB - - - - - - -
PGHHMJKG_03968 1.79e-56 ylaC - - K ko:K03088 - ko00000,ko03021 Belongs to the sigma-70 factor family. ECF subfamily
PGHHMJKG_03970 1.74e-57 ylaE - - - - - - -
PGHHMJKG_03971 2.21e-30 - - - S - - - Family of unknown function (DUF5325)
PGHHMJKG_03972 0.0 typA - - T ko:K06207 - ko00000 GTP-binding protein TypA
PGHHMJKG_03973 4.4e-63 ylaH - - S - - - YlaH-like protein
PGHHMJKG_03974 8.92e-44 ylaI - - S - - - protein conserved in bacteria
PGHHMJKG_03975 2.44e-126 ylaJ - - S - - - Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PGHHMJKG_03976 1.41e-315 ylaK - - T ko:K07175 - ko00000 ATPase related to phosphate starvation-inducible protein PhoH
PGHHMJKG_03977 9.32e-112 ylaL - - S - - - Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PGHHMJKG_03978 3.49e-219 glsA 3.5.1.2 - E ko:K01425 ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230 ko00000,ko00001,ko01000 Belongs to the glutaminase family
PGHHMJKG_03979 6.94e-59 ylaN - - S - - - Belongs to the UPF0358 family
PGHHMJKG_03980 2.35e-269 ftsW - - D ko:K03588 ko04112,map04112 ko00000,ko00001,ko02000,ko03036 Belongs to the SEDS family
PGHHMJKG_03981 0.0 pyc 6.4.1.1 - C ko:K01958 ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PGHHMJKG_03982 8.32e-151 ykwD - - J - - - protein with SCP PR1 domains
PGHHMJKG_03983 0.0 pbp2b - - M ko:K00687,ko:K12553,ko:K21465,ko:K21466 ko00550,ko01100,ko01501,map00550,map01100,map01501 ko00000,ko00001,ko01000,ko01011 Penicillin-binding Protein
PGHHMJKG_03984 0.0 kinA 2.7.13.3 - T ko:K02491 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 Histidine kinase
PGHHMJKG_03985 1.78e-284 patA - - E ko:K00841 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01007 Aminotransferase
PGHHMJKG_03986 1.05e-22 - - - - - - - -
PGHHMJKG_03987 4.95e-216 cheV - - T ko:K03408,ko:K03415 ko02020,ko02030,map02020,map02030 ko00000,ko00001,ko00002,ko02022,ko02035 Chemotaxis protein CheV
PGHHMJKG_03988 3.71e-110 ykyB - - S - - - YkyB-like protein
PGHHMJKG_03989 2.55e-305 ykuC - - EGP - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_03990 5.84e-115 ykuD - - S - - - protein conserved in bacteria
PGHHMJKG_03991 1.42e-211 ykuE - - S ko:K07098 - ko00000 Metallophosphoesterase
PGHHMJKG_03992 2.6e-182 fadH 1.3.1.34 - IQ ko:K00219 - ko00000,ko01000 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PGHHMJKG_03993 1.76e-298 ykuI - - T - - - Diguanylate phosphodiesterase
PGHHMJKG_03994 5.16e-50 ykuJ - - S - - - protein conserved in bacteria
PGHHMJKG_03995 6.44e-122 - - - S ko:K09776 - ko00000 Ribonuclease H-like
PGHHMJKG_03996 7.83e-38 ykzF - - S - - - Antirepressor AbbA
PGHHMJKG_03997 6.01e-99 ykuL - - S - - - CBS domain
PGHHMJKG_03998 7.61e-215 ccpC - - K - - - Transcriptional regulator
PGHHMJKG_03999 6.35e-113 - - - C ko:K03839 - ko00000 Flavodoxin domain
PGHHMJKG_04000 1.74e-222 ykuO - - - - - - -
PGHHMJKG_04001 2.95e-101 fld - - C ko:K03839 - ko00000 Flavodoxin
PGHHMJKG_04002 1.31e-125 dapH 2.3.1.117, 2.3.1.89 - E ko:K00674,ko:K05822 ko00300,ko01100,ko01110,ko01120,ko01230,map00300,map01100,map01110,map01120,map01230 ko00000,ko00001,ko00002,ko01000 Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PGHHMJKG_04003 4.43e-273 hipO 3.5.1.47 - E ko:K05823 ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000,ko01002 Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PGHHMJKG_04004 7.23e-51 ykuS - - S - - - Belongs to the UPF0180 family
PGHHMJKG_04005 4.1e-181 ykuT - - M ko:K22044 - ko00000,ko02000 Mechanosensitive ion channel
PGHHMJKG_04006 9.78e-130 ykuU - - O - - - Alkyl hydroperoxide reductase
PGHHMJKG_04007 4.23e-104 ykuV - - CO - - - thiol-disulfide
PGHHMJKG_04008 4.71e-122 rok - - K - - - Repressor of ComK
PGHHMJKG_04009 1.77e-236 fabHB 2.3.1.180 - I ko:K00648 ko00061,ko01100,ko01212,map00061,map01100,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PGHHMJKG_04010 3.8e-177 yhfC - - S - - - Putative membrane peptidase family (DUF2324)
PGHHMJKG_04011 1.55e-252 yhfE - - G - - - peptidase M42
PGHHMJKG_04012 1.79e-92 - - - S - - - ASCH
PGHHMJKG_04013 4.77e-289 gltT - - C ko:K03309,ko:K11102,ko:K11103 ko02020,map02020 ko00000,ko00001,ko02000 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PGHHMJKG_04014 1.63e-180 yhfI - - S - - - COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PGHHMJKG_04015 4.06e-245 lplJ 6.3.1.20 - H ko:K03800 ko00785,ko01100,map00785,map01100 ko00000,ko00001,ko01000 Lipoate-protein ligase
PGHHMJKG_04016 1.01e-141 yhfK - - GM - - - NmrA-like family
PGHHMJKG_04017 0.0 yhfL 6.2.1.3 - IQ ko:K00666,ko:K01897 ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920 ko00000,ko00001,ko00002,ko01000,ko01004,ko04147 AMP-binding enzyme C-terminal domain
PGHHMJKG_04018 8.76e-104 fri - - P ko:K04047 - ko00000,ko03036 Ferritin-like domain
PGHHMJKG_04019 2.71e-176 yusZ - - IQ - - - Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_04020 5.75e-160 - 2.3.1.29 - H ko:K00639 ko00260,map00260 ko00000,ko00001,ko01000,ko01007 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PGHHMJKG_04021 1.26e-18 - - - - - - - -
PGHHMJKG_04023 3.05e-20 - - - S - - - Evidence 4 Homologs of previously reported genes of
PGHHMJKG_04025 2.94e-17 - - - EGP - - - Major Facilitator
PGHHMJKG_04026 6.4e-09 - - - J - - - O-methyltransferase
PGHHMJKG_04027 3.54e-95 ecsA - - V ko:K01990 - ko00000,ko00002,ko02000 ABC superfamily ATP binding cassette transporter ABC protein
PGHHMJKG_04028 2.98e-14 ecsB - - U ko:K01992 - ko00000,ko00002,ko02000 ABC transporter
PGHHMJKG_04030 0.0 pepF2 - - E - - - COG1164 Oligoendopeptidase F
PGHHMJKG_04031 3.48e-88 - - - S - - - YusW-like protein
PGHHMJKG_04032 8.74e-196 yusV 3.6.3.34 - HP ko:K02013 ko02010,map02010 ko00000,ko00001,ko00002,ko01000,ko02000 ABC transporter
PGHHMJKG_04033 3.99e-53 yusU - - S - - - Protein of unknown function (DUF2573)
PGHHMJKG_04034 5.68e-202 gltR - - K ko:K21959 - ko00000,ko03000 LysR substrate binding domain
PGHHMJKG_04035 4.97e-138 yusR 1.1.1.100 - IQ ko:K00059 ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212 ko00000,ko00001,ko00002,ko01000,ko01004 Belongs to the short-chain dehydrogenases reductases (SDR) family
PGHHMJKG_04036 4.86e-84 yusQ - - S - - - Tautomerase enzyme
PGHHMJKG_04037 0.0 yusP - - P - - - Major facilitator superfamily
PGHHMJKG_04038 6.35e-98 yusO - - K - - - Iron dependent repressor, N-terminal DNA binding domain
PGHHMJKG_04039 8.66e-70 yusN - - M - - - Coat F domain
PGHHMJKG_04040 2.23e-54 - - - - - - - -
PGHHMJKG_04041 8.15e-210 fadM - - E ko:K00318 ko00330,ko01100,ko01110,ko01130,map00330,map01100,map01110,map01130 ko00000,ko00001,ko01000 Proline dehydrogenase
PGHHMJKG_04042 1.11e-13 - - - S - - - YuzL-like protein
PGHHMJKG_04043 0.0 fadN 1.1.1.35 - I ko:K07516 ko00071,ko00362,ko00650,ko01100,ko01120,ko01200,ko01212,map00071,map00362,map00650,map01100,map01120,map01200,map01212 ko00000,ko00001,ko00002,ko01000 3-hydroxyacyl-CoA dehydrogenase
PGHHMJKG_04044 3.15e-277 fadA 2.3.1.16 - I ko:K00632 ko00071,ko00280,ko00281,ko00362,ko00592,ko00642,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00362,map00592,map00642,map01100,map01110,map01120,map01130,map01212 ko00000,ko00001,ko00002,ko01000 Belongs to the thiolase family
PGHHMJKG_04045 0.0 fadE 1.3.8.1 - I ko:K00248 ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212 ko00000,ko00001,ko01000 acyl-CoA dehydrogenase
PGHHMJKG_04046 1.01e-83 yusI 1.20.4.1 - P ko:K00537 - ko00000,ko01000 Belongs to the ArsC family
PGHHMJKG_04047 5.91e-85 gcvH - - E ko:K02437 ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200 ko00000,ko00001,ko00002 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PGHHMJKG_04048 2.11e-53 yusG - - S - - - Protein of unknown function (DUF2553)
PGHHMJKG_04049 8.9e-96 yusF - - L ko:K07476 - ko00000 COG1658 Small primase-like proteins (Toprim domain)
PGHHMJKG_04050 8.14e-73 yusE - - CO - - - Thioredoxin
PGHHMJKG_04051 1.53e-74 yusD - - S - - - SCP-2 sterol transfer family
PGHHMJKG_04052 2.15e-236 metN - - P ko:K02071 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PGHHMJKG_04053 6.5e-126 metI - - P ko:K02069,ko:K02072 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG2011 ABC-type metal ion transport system, permease component
PGHHMJKG_04054 1.96e-187 metQ - - P ko:K02072,ko:K02073 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 Belongs to the NlpA lipoprotein family
PGHHMJKG_04055 1.56e-80 yurZ - - S - - - Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PGHHMJKG_04056 4.46e-182 sufC - - O ko:K09013 - ko00000,ko02000 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PGHHMJKG_04057 6.1e-312 sufD - - O ko:K07033,ko:K09015 - ko00000 assembly protein SufD
PGHHMJKG_04058 2.81e-299 sufS 2.8.1.7, 4.4.1.16 - E ko:K11717 ko00450,ko01100,map00450,map01100 ko00000,ko00001,ko01000 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PGHHMJKG_04059 6.26e-101 nifU - - C ko:K04488 - ko00000 COG0822 NifU homolog involved in Fe-S cluster formation
PGHHMJKG_04060 0.0 sufB - - O ko:K07033,ko:K09014 - ko00000 FeS cluster assembly
PGHHMJKG_04061 1.79e-149 - - - L - - - Belongs to the 'phage' integrase family
PGHHMJKG_04065 7.24e-60 - - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_04066 1.7e-08 - - - K - - - Helix-turn-helix XRE-family like proteins
PGHHMJKG_04067 4.59e-23 - - - - - - - -
PGHHMJKG_04069 2.79e-87 - - - L - - - dnaD_dom DnaD domain protein
PGHHMJKG_04070 2.01e-64 - - - L ko:K02315,ko:K11144 - ko00000,ko03032 DNA replication protein
PGHHMJKG_04072 1.88e-09 - - - - - - - -
PGHHMJKG_04073 5.02e-188 hemD 4.2.1.75 - H ko:K01719 ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120 ko00000,ko00001,ko00002,ko01000 Uroporphyrinogen-III synthase
PGHHMJKG_04074 1.11e-41 - - - - - - - -
PGHHMJKG_04075 1.76e-279 yjiC - - CG - - - COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PGHHMJKG_04076 4.06e-287 yjiB 1.14.14.46, 1.14.15.13 - C ko:K15468,ko:K16593,ko:K17474 ko00780,ko01100,map00780,map01100 ko00000,ko00001,ko00002,ko00199,ko01000,ko01008 Cytochrome P450
PGHHMJKG_04078 8.38e-144 yjhB 3.6.1.13 - F ko:K01515 ko00230,map00230 ko00000,ko00001,ko01000 ADP-ribose pyrophosphatase
PGHHMJKG_04080 5.25e-113 yjgD - - S - - - Protein of unknown function (DUF1641)
PGHHMJKG_04081 0.0 yjgC 1.17.1.9 - C ko:K00123 ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200 ko00000,ko00001,ko01000 formate dehydrogenase (NAD+) activity
PGHHMJKG_04082 4.08e-132 yjgB - - S - - - Domain of unknown function (DUF4309)
PGHHMJKG_04083 1.38e-59 yjgA - - T - - - Protein of unknown function (DUF2809)
PGHHMJKG_04084 3.15e-136 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
PGHHMJKG_04085 1.93e-62 yjfC - - O - - - Predicted Zn-dependent protease (DUF2268)
PGHHMJKG_04086 1.13e-29 yjfB - - S - - - Putative motility protein
PGHHMJKG_04087 9.03e-108 - - - S - - - Protein of unknown function (DUF2690)
PGHHMJKG_04088 0.0 yjeA 3.5.1.104 - G ko:K22278 - ko00000,ko01000 Polysaccharide deacetylase
PGHHMJKG_04090 8.79e-223 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PGHHMJKG_04091 2.7e-68 yjdJ - - S - - - Domain of unknown function (DUF4306)
PGHHMJKG_04092 6.12e-40 - - - S - - - Domain of unknown function (DUF4177)
PGHHMJKG_04093 9.69e-104 ebsC - - S ko:K03976 - ko00000,ko01000,ko03016 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PGHHMJKG_04095 2.17e-118 - 2.3.1.128 - J ko:K03790 - ko00000,ko01000,ko03009 Acetyltransferase (GNAT) domain
PGHHMJKG_04096 1.52e-185 - - - T ko:K17763 - ko00000,ko03021 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PGHHMJKG_04097 3.81e-28 yezD - - S - - - Uncharacterized small protein (DUF2292)
PGHHMJKG_04098 4.23e-134 yetJ - - S ko:K06890 - ko00000 Belongs to the BI1 family
PGHHMJKG_04099 1.3e-38 yetM - - CH - - - FAD binding domain
PGHHMJKG_04100 5.94e-131 mrr2 - - L ko:K07448 - ko00000,ko02048 restriction endonuclease
PGHHMJKG_04101 1.94e-248 yetN - - S - - - Protein of unknown function (DUF3900)
PGHHMJKG_04102 0.0 cypD 1.14.14.1, 1.6.2.4 - C ko:K14338 ko00071,ko00380,ko00627,ko01120,map00071,map00380,map00627,map01120 ko00000,ko00001,ko00199,ko01000 Belongs to the cytochrome P450 family
PGHHMJKG_04103 0.0 ltaS 2.7.8.20 - M ko:K19005 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko01000 Belongs to the LTA synthase family
PGHHMJKG_04104 5.07e-189 yfnH 2.7.7.33 - JM ko:K00978 ko00500,ko00520,ko01100,map00500,map00520,map01100 ko00000,ko00001,ko01000 Nucleotidyl transferase
PGHHMJKG_04105 4.79e-220 yfnG 4.2.1.45, 4.2.1.46 - M ko:K01709,ko:K01710 ko00520,ko00521,ko00523,ko00525,ko01055,ko01130,map00520,map00521,map00523,map00525,map01055,map01130 ko00000,ko00001,ko00002,ko01000 dehydratase
PGHHMJKG_04106 2.69e-229 yfnF - - M - - - Nucleotide-diphospho-sugar transferase
PGHHMJKG_04107 6.7e-284 yfnE - - S - - - Glycosyltransferase like family 2
PGHHMJKG_04108 2.34e-243 yfnD - - M - - - Nucleotide-diphospho-sugar transferase
PGHHMJKG_04109 7.24e-267 fsr - - P ko:K08223 - ko00000,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_04110 2.05e-165 yfnB 3.8.1.2 - S ko:K01560,ko:K07025 ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120 ko00000,ko00001,ko01000 Haloacid dehalogenase-like hydrolase
PGHHMJKG_04111 2.4e-312 yfnA - - E ko:K03294 - ko00000 amino acid
PGHHMJKG_04112 0.0 yfmT 1.2.1.3, 1.2.1.67 - C ko:K00128,ko:K21802 ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00627,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00627,map00903,map00981,map01100,map01110,map01120,map01130 ko00000,ko00001,ko00002,ko01000 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PGHHMJKG_04113 5.14e-161 yfmS - - NT - - - chemotaxis protein
PGHHMJKG_04114 0.0 yfmR - - S ko:K15738 - ko00000,ko02000 COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PGHHMJKG_04115 4.39e-97 yfmQ - - S - - - Uncharacterised protein from bacillus cereus group
PGHHMJKG_04116 3.54e-90 yfmP - - K ko:K21902 - ko00000,ko03000 transcriptional
PGHHMJKG_04117 3.59e-265 yfmO - - EGP ko:K08221 - ko00000,ko02000 Major facilitator superfamily
PGHHMJKG_04118 2.1e-39 - - - - - - - -
PGHHMJKG_04121 1.81e-37 bhlA - - S - - - BhlA holin family
PGHHMJKG_04122 3.19e-41 xhlB - - S - - - SPP1 phage holin
PGHHMJKG_04123 7.81e-167 xlyB 3.5.1.28 - M ko:K01447 - ko00000,ko01000 N-acetylmuramoyl-L-alanine amidase
PGHHMJKG_04124 8.88e-87 - - - S - - - Immunity protein 70
PGHHMJKG_04125 6.57e-233 - - - A ko:K21491 - ko00000,ko01000,ko02048 Pre-toxin TG
PGHHMJKG_04127 7.52e-55 - - - S - - - protein domain associated with
PGHHMJKG_04129 6.75e-38 - - - K - - - Helix-turn-helix domain
PGHHMJKG_04131 5.85e-35 - - - U - - - Preprotein translocase subunit SecB
PGHHMJKG_04135 1.17e-148 - - - - - - - -
PGHHMJKG_04136 5.53e-175 - - - - - - - -
PGHHMJKG_04137 0.0 gutR - - K ko:K16247 - ko00000,ko03000 NB-ARC domain
PGHHMJKG_04138 2.5e-257 gutB 1.1.1.14 - E ko:K00008 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko00002,ko01000 Dehydrogenase
PGHHMJKG_04139 0.0 gutP - - G ko:K03292,ko:K16248 - ko00000,ko02000 MFS/sugar transport protein
PGHHMJKG_04140 4.95e-220 ydjE 2.7.1.4 - G ko:K00847 ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100 ko00000,ko00001,ko01000 pfkB family carbohydrate kinase
PGHHMJKG_04141 8.88e-147 pspA - - KT ko:K03969 - ko00000 Phage shock protein A
PGHHMJKG_04142 3.64e-228 ydjG - - L - - - Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PGHHMJKG_04143 3.21e-167 ydjH - - S ko:K06872 - ko00000 COG1512 Beta-propeller domains of methanol dehydrogenase type
PGHHMJKG_04144 3.61e-203 ydjI - - S - - - virion core protein (lumpy skin disease virus)
PGHHMJKG_04145 4.11e-183 - - - S - - - Ion transport 2 domain protein
PGHHMJKG_04146 1.91e-33 - - - S - - - Ion transport 2 domain protein
PGHHMJKG_04147 0.0 iolT - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGHHMJKG_04148 3.5e-249 ydjL 1.1.1.264, 1.1.1.303, 1.1.1.4 - E ko:K00004,ko:K00098 ko00650,map00650 ko00000,ko00001,ko01000 Dehydrogenase
PGHHMJKG_04149 1.79e-84 ydjM - - M - - - Lytic transglycolase
PGHHMJKG_04150 1.62e-207 ydjN - - U - - - Involved in the tonB-independent uptake of proteins
PGHHMJKG_04153 0.0 - - - V - - - Beta-lactamase
PGHHMJKG_04155 3.11e-12 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PGHHMJKG_04157 4.82e-69 ynaF - - - - - - -
PGHHMJKG_04158 1.4e-104 - - - S - - - Domain of unknown function (DUF3885)
PGHHMJKG_04160 4.01e-36 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PGHHMJKG_04161 4.98e-106 yoaW - - - - - - -
PGHHMJKG_04162 3.46e-10 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PGHHMJKG_04163 7.66e-99 - - - - - - - -
PGHHMJKG_04164 3.2e-59 yoaQ - - S - - - Evidence 4 Homologs of previously reported genes of
PGHHMJKG_04165 4.46e-23 - - - - - - - -
PGHHMJKG_04167 1.57e-121 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_04169 3.91e-52 ydaF - - J ko:K03817 - ko00000,ko01000,ko03009 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PGHHMJKG_04170 0.000751 yabB 2.1.1.223 - S ko:K07461,ko:K15460 - ko00000,ko01000,ko03016 Methyltransferase small domain
PGHHMJKG_04171 4.01e-33 - 2.7.7.80 - H ko:K21029 ko04122,map04122 ko00000,ko00001,ko01000 ThiF family
PGHHMJKG_04172 2.14e-17 - - - Q - - - methyltransferase
PGHHMJKG_04175 5.08e-26 xkdM - - S - - - Phage tail tube protein
PGHHMJKG_04176 2.43e-14 - - - - - - - -
PGHHMJKG_04179 7.44e-05 - - - S - - - Bacillus cereus group antimicrobial protein
PGHHMJKG_04182 1.24e-194 bltR - - K - - - helix_turn_helix, mercury resistance
PGHHMJKG_04183 1.08e-268 blt - - EGP ko:K08153,ko:K19578 - ko00000,ko00002,ko02000 COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_04184 7.23e-107 bltD 2.3.1.57 - K ko:K00657 ko00330,ko01100,ko04216,map00330,map01100,map04216 ko00000,ko00001,ko00002,ko01000 FR47-like protein
PGHHMJKG_04185 7.89e-210 thyA 2.1.1.45 - F ko:K00560 ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523 ko00000,ko00001,ko00002,ko01000 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PGHHMJKG_04188 7.54e-22 - - - - - - - -
PGHHMJKG_04189 1.22e-101 yncF 3.6.1.23 - F ko:K01520 ko00240,ko00983,ko01100,map00240,map00983,map01100 ko00000,ko00001,ko00002,ko01000,ko03400 Deoxyuridine 5'-triphosphate
PGHHMJKG_04191 4.34e-281 alr 5.1.1.1 - E ko:K01775 ko00473,ko01100,ko01502,map00473,map01100,map01502 ko00000,ko00001,ko01000,ko01011 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PGHHMJKG_04192 0.0 - - - U ko:K02100,ko:K06609,ko:K08139 ko04113,map04113 ko00000,ko00001,ko02000 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PGHHMJKG_04193 7.18e-145 yokF 3.1.31.1 - L ko:K01174 - ko00000,ko01000 RNA catabolic process
PGHHMJKG_04204 4.03e-07 ftsK - - D ko:K03466 - ko00000,ko03036 DNA segregation ATPase FtsK SpoIIIE and related proteins
PGHHMJKG_04209 8.34e-26 - - - K ko:K06284 - ko00000,ko03000 SpoVT / AbrB like domain
PGHHMJKG_04210 6.48e-34 - - - S - - - Repressor of ComK
PGHHMJKG_04214 1.88e-51 ydbT - - S ko:K08981 - ko00000 Bacterial PH domain
PGHHMJKG_04215 6.99e-09 - - - S ko:K09167 - ko00000 Bacterial PH domain
PGHHMJKG_04216 1.63e-09 - - - - - - - -
PGHHMJKG_04226 2.23e-50 csgA - - S - - - Sigma-G-dependent sporulation-specific SASP protein
PGHHMJKG_04227 6.92e-41 ybxH - - S - - - Family of unknown function (DUF5370)
PGHHMJKG_04228 1.24e-191 ybxI 3.5.2.6 - V ko:K17838 ko01501,map01501 ko00000,ko00001,ko01000 beta-lactamase
PGHHMJKG_04229 2.99e-311 cypC 1.11.2.4 - Q ko:K15629 - ko00000,ko00199,ko01000 Cytochrome P450
PGHHMJKG_04230 1.28e-37 ybyB - - - - - - -
PGHHMJKG_04231 0.0 ybeC - - E - - - amino acid
PGHHMJKG_04232 2.09e-212 glpQ 3.1.3.1, 3.1.4.46 - C ko:K01113,ko:K01126 ko00564,ko00790,ko01100,ko02020,map00564,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 glycerophosphoryl diester phosphodiesterase
PGHHMJKG_04233 0.0 glpT - - G ko:K02445 - ko00000,ko02000 -transporter
PGHHMJKG_04234 3.57e-47 - - - S - - - Protein of unknown function (DUF2651)
PGHHMJKG_04235 8.65e-202 ybfA - - K - - - FR47-like protein
PGHHMJKG_04236 5.4e-184 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_04237 6.21e-57 ybfB - - G - - - COG0477 Permeases of the major facilitator superfamily
PGHHMJKG_04240 0.0 ybfG - - M - - - Domain of unknown function (DUF1906)
PGHHMJKG_04241 5.01e-133 ybfH - - EG - - - EamA-like transporter family
PGHHMJKG_04242 2.88e-185 ybfI - - K - - - AraC-like ligand binding domain
PGHHMJKG_04243 3.63e-43 - - - K - - - sigma factor activity
PGHHMJKG_04244 2.73e-28 xhlB - - S - - - SPP1 phage holin
PGHHMJKG_04245 4.74e-185 - - GH19 M ko:K03791 - ko00000 Lysin motif
PGHHMJKG_04246 2.61e-73 - - - - - - - -
PGHHMJKG_04247 1.54e-269 purT 2.1.2.2 - F ko:K08289 ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PGHHMJKG_04248 3.97e-227 mpr - - M - - - Belongs to the peptidase S1B family
PGHHMJKG_04250 1.31e-212 - - - S - - - Alpha/beta hydrolase family
PGHHMJKG_04251 6.9e-124 pssA 2.7.8.8 - I ko:K17103 ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PGHHMJKG_04252 7.07e-112 ybfM - - S - - - SNARE associated Golgi protein
PGHHMJKG_04253 6.15e-190 psd 4.1.1.65 - I ko:K01613 ko00564,ko01100,ko01110,map00564,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PGHHMJKG_04254 2.25e-59 ybfN - - - - - - -
PGHHMJKG_04255 0.0 - - - S ko:K06880 - ko00000,ko01000,ko01504 Erythromycin esterase
PGHHMJKG_04256 5.14e-214 ybfP - - K ko:K13653 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_04257 2.35e-244 ybfQ - - S ko:K07146 - ko00000 Belongs to the UPF0176 family
PGHHMJKG_04258 4.72e-211 ctaA - - O ko:K02259 ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714 ko00000,ko00001,ko00002,ko03029 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PGHHMJKG_04259 1.7e-208 ctaB 2.5.1.141 - O ko:K02257 ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714 ko00000,ko00001,ko00002,ko01000,ko01006,ko03029 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PGHHMJKG_04260 9.7e-252 ctaC 1.9.3.1 - C ko:K02275 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PGHHMJKG_04261 0.0 ctaD 1.9.3.1 - C ko:K02274 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PGHHMJKG_04262 1.84e-145 ctaE 1.9.3.1 - C ko:K02276 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PGHHMJKG_04263 1.75e-69 ctaF 1.9.3.1 - C ko:K02277 ko00190,ko01100,map00190,map01100 ko00000,ko00001,ko00002,ko01000 COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PGHHMJKG_04264 9.56e-211 ctaG - - S ko:K02862 - ko00000 cytochrome c oxidase
PGHHMJKG_04265 1.61e-81 ylbA - - S - - - YugN-like family
PGHHMJKG_04266 1.53e-97 ylbB - - T - - - COG0517 FOG CBS domain
PGHHMJKG_04267 4.39e-256 ylbC - - S - - - protein with SCP PR1 domains
PGHHMJKG_04268 3.78e-88 ylbD - - S - - - Putative coat protein
PGHHMJKG_04269 1.73e-48 ylbE - - S - - - YlbE-like protein
PGHHMJKG_04270 5.95e-306 srfAA - - Q ko:K15654,ko:K15655,ko:K16119 ko01054,ko02024,map01054,map02024 ko00000,ko00001,ko01008 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PGHHMJKG_04272 2.61e-15 - - - S - - - Protein of unknown function (DUF1433)
PGHHMJKG_04273 8.3e-126 ynaD - - J - - - Acetyltransferase (GNAT) domain
PGHHMJKG_04275 3.24e-93 - - - S - - - CAAX protease self-immunity
PGHHMJKG_04276 2.38e-11 ywlA - - S - - - Uncharacterised protein family (UPF0715)
PGHHMJKG_04277 8.64e-34 - - - K ko:K07727 - ko00000,ko03000 Cro/C1-type HTH DNA-binding domain
PGHHMJKG_04278 4.84e-09 - - - S - - - Domain of unknown function (DUF3885)
PGHHMJKG_04279 1.9e-102 - - - S - - - Domain of unknown function (DUF3885)
PGHHMJKG_04280 2.77e-19 ynaF - - - - - - -
PGHHMJKG_04282 2.81e-106 - - - E - - - phosphoribosylanthranilate isomerase activity
PGHHMJKG_04283 0.0 xynP - - G ko:K03292 - ko00000 MFS/sugar transport protein
PGHHMJKG_04284 0.0 xynB 3.2.1.37 GH43 G ko:K01198 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Belongs to the glycosyl hydrolase 43 family
PGHHMJKG_04285 6.82e-273 xylR - - GK - - - ROK family
PGHHMJKG_04286 0.0 xylA 5.3.1.5 - G ko:K01805 ko00040,ko00051,ko01100,map00040,map00051,map01100 ko00000,ko00001,ko01000 Belongs to the xylose isomerase family
PGHHMJKG_04287 0.0 xylB 2.7.1.17 - G ko:K00854 ko00040,ko01100,map00040,map01100 ko00000,ko00001,ko00002,ko01000 xylulose kinase
PGHHMJKG_04304 2.11e-251 galE 5.1.3.2 - M ko:K01784 ko00052,ko00520,ko01100,map00052,map00520,map01100 ko00000,ko00001,ko00002,ko01000 Belongs to the NAD(P)-dependent epimerase dehydratase family
PGHHMJKG_04305 3.81e-100 - - - S - - - Protein of unknown function (DUF1453)
PGHHMJKG_04306 1.76e-166 - - - T - - - Signal transduction histidine kinase
PGHHMJKG_04307 8.24e-73 - - - T - - - Signal transduction histidine kinase
PGHHMJKG_04308 2.69e-148 - - - K ko:K02479 - ko00000,ko02022 helix_turn_helix, Lux Regulon
PGHHMJKG_04309 1.83e-297 pepT 3.4.11.4 - E ko:K01258 - ko00000,ko01000,ko01002 Cleaves the N-terminal amino acid of tripeptides
PGHHMJKG_04311 2.88e-111 yxjI - - S - - - LURP-one-related
PGHHMJKG_04312 2.13e-277 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PGHHMJKG_04313 2.21e-275 yxjG 2.1.1.14 - E ko:K00549 ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230 ko00000,ko00001,ko00002,ko01000 Methionine synthase
PGHHMJKG_04314 1.67e-175 yxjF 1.1.1.30 - IQ ko:K00019 ko00072,ko00650,ko01100,map00072,map00650,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PGHHMJKG_04315 1.69e-150 scoB 2.8.3.5 - I ko:K01029 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PGHHMJKG_04316 6.6e-168 scoA 2.8.3.5 - I ko:K01028 ko00072,ko00280,ko00650,map00072,map00280,map00650 ko00000,ko00001,ko01000 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PGHHMJKG_04317 0.0 yxjC - - EG - - - COG2610 H gluconate symporter and related permeases
PGHHMJKG_04318 9.07e-197 yxjB 2.1.1.187 - Q ko:K00563 - ko00000,ko01000,ko03009 Methyltransferase domain
PGHHMJKG_04319 3.47e-268 nupG - - F ko:K16323 - ko00000,ko02000 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PGHHMJKG_04320 1.51e-91 - - - T - - - Domain of unknown function (DUF4163)
PGHHMJKG_04321 2.28e-63 yxiS - - - - - - -
PGHHMJKG_04322 0.0 katE 1.11.1.6 - P ko:K03781 ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014 ko00000,ko00001,ko00002,ko01000 serves to protect cells from the toxic effects of hydrogen peroxide
PGHHMJKG_04323 2e-284 citH - - C ko:K03300,ko:K11639 ko02020,map02020 ko00000,ko00001 Citrate transporter
PGHHMJKG_04324 7.21e-183 bglS - - M - - - licheninase activity
PGHHMJKG_04325 5.66e-193 licT - - K ko:K03488 - ko00000,ko03000 transcriptional antiterminator
PGHHMJKG_04326 7.23e-141 - - - - - - - -
PGHHMJKG_04327 3.8e-292 yxiO - - S ko:K06902 ko04138,map04138 ko00000,ko00001,ko02000,ko04131 COG2270 Permeases of the major facilitator superfamily
PGHHMJKG_04328 0.0 dbpA 3.6.4.13 - JKL ko:K05592 ko03018,map03018 ko00000,ko00001,ko01000,ko03009,ko03019 DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PGHHMJKG_04329 3.52e-274 - - - E - - - GDSL-like Lipase/Acylhydrolase
PGHHMJKG_04332 4.06e-58 yxiJ - - S - - - YxiJ-like protein
PGHHMJKG_04335 1.86e-40 - - - - - - - -
PGHHMJKG_04336 8.21e-50 yxiI - - S - - - Protein of unknown function (DUF2716)
PGHHMJKG_04337 3.42e-173 - - - - - - - -
PGHHMJKG_04340 6.09e-50 - - - S - - - Protein of unknown function (DUF2750)
PGHHMJKG_04341 9.7e-68 yxxG - - - - - - -
PGHHMJKG_04342 4.67e-89 yxiG - - - - - - -
PGHHMJKG_04343 4.48e-58 - - - - - - - -
PGHHMJKG_04344 7.13e-100 - - - - - - - -
PGHHMJKG_04345 8.9e-119 - - - S - - - Protein of unknown function (DUF4240)
PGHHMJKG_04346 5.06e-175 - - - - - - - -
PGHHMJKG_04348 1.27e-69 - - - - - - - -
PGHHMJKG_04349 6.47e-100 wapA - - M - - - COG3209 Rhs family protein
PGHHMJKG_04350 8.8e-241 manA 5.3.1.8 - G ko:K01809 ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130 ko00000,ko00001,ko00002,ko01000 mannose-6-phosphate isomerase
PGHHMJKG_04351 0.0 manP 2.7.1.202 - G ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 phosphotransferase system
PGHHMJKG_04352 0.0 manR - - GKT ko:K02538,ko:K03491 - ko00000,ko03000 transcriptional antiterminator
PGHHMJKG_04353 2.43e-58 yjcN - - - - - - -
PGHHMJKG_04354 3.01e-60 yjcS - - S - - - Antibiotic biosynthesis monooxygenase
PGHHMJKG_04355 1.08e-60 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_04356 1.12e-33 - - - S ko:K06359,ko:K06360,ko:K06367 ko02024,map02024 ko00000,ko00001,ko01000 Response regulator aspartate phosphatase
PGHHMJKG_04362 4.58e-68 yccK - - C - - - Aldo keto reductase
PGHHMJKG_04363 2.9e-28 yccK - - C - - - Aldo keto reductase
PGHHMJKG_04364 9.75e-258 - - - CP ko:K09696 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko02000 ABC-2 family transporter protein
PGHHMJKG_04365 5.41e-171 natA 3.6.3.7 - CP ko:K01990,ko:K09697 ko02010,ko02020,map02010,map02020 ko00000,ko00001,ko00002,ko01000,ko02000 ATPases associated with a variety of cellular activities
PGHHMJKG_04366 6.86e-163 natR - - T ko:K02477,ko:K11641 ko02020,map02020 ko00000,ko00001,ko00002,ko02022 LytTr DNA-binding domain
PGHHMJKG_04367 6.18e-213 natK 2.7.13.3 - T ko:K11640 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 GHKL domain
PGHHMJKG_04368 7.13e-255 yccF - - K ko:K07039 - ko00000 SEC-C motif
PGHHMJKG_04369 4.32e-78 - - - S - - - RDD family
PGHHMJKG_04370 4e-147 - 3.1.1.3 - S ko:K01046 ko00561,ko01100,map00561,map01100 ko00000,ko00001,ko00002,ko01000 acetyltransferases and hydrolases with the alpha beta hydrolase fold
PGHHMJKG_04371 8.02e-256 ansB 3.5.1.1 - EJ ko:K01424 ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110 ko00000,ko00001,ko01000 COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PGHHMJKG_04372 7.64e-131 lmrA - - K ko:K18939 - ko00000,ko00002,ko03000 Transcriptional regulator
PGHHMJKG_04373 1.45e-301 lmrB - - EGP ko:K18926 - ko00000,ko00002,ko02000 the major facilitator superfamily
PGHHMJKG_04374 1.39e-258 ycbU - - E - - - Selenocysteine lyase
PGHHMJKG_04375 4.68e-152 pcp 3.4.19.3 - O ko:K01304 - ko00000,ko01000,ko01002 Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PGHHMJKG_04376 3.61e-158 tatC - - U ko:K03118 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PGHHMJKG_04377 3.12e-38 tatAD - - U ko:K03116 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02044 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PGHHMJKG_04378 0.0 phoD 3.1.3.1 - P ko:K01113 ko00790,ko01100,ko02020,map00790,map01100,map02020 ko00000,ko00001,ko00002,ko01000 COG3540 Phosphodiesterase alkaline phosphatase D
PGHHMJKG_04379 3.83e-174 ycbR - - T - - - vWA found in TerF C terminus
PGHHMJKG_04380 9.58e-67 - - - M - - - ArpU family transcriptional regulator
PGHHMJKG_04381 1.6e-94 - - - L - - - Phage integrase family
PGHHMJKG_04382 8.22e-48 - - - S - - - Protein of unknown function (DUF1433)
PGHHMJKG_04383 0.0 lysS 6.1.1.6 - J ko:K04567 ko00970,map00970 ko00000,ko00001,ko00002,ko01000,ko01007,ko03016 Belongs to the class-II aminoacyl-tRNA synthetase family
PGHHMJKG_04384 3.75e-242 dus - - J ko:K05540 - ko00000,ko01000,ko03016 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PGHHMJKG_04385 1.81e-41 yazB - - K - - - transcriptional
PGHHMJKG_04386 1.31e-114 folK 2.7.6.3 - H ko:K00950 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PGHHMJKG_04387 3.8e-80 folB 1.13.11.81, 4.1.2.25, 5.1.99.8 - H ko:K01633 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PGHHMJKG_04388 5.28e-202 folP 2.5.1.15 - H ko:K00796 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko00002,ko01000 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PGHHMJKG_04389 2.09e-212 pabC 4.1.3.38 - EH ko:K02619 ko00790,map00790 ko00000,ko00001,ko01000 4-amino-4-deoxychorismate lyase
PGHHMJKG_04390 2.44e-136 pabA 2.6.1.85 - EH ko:K01664 ko00790,map00790 ko00000,ko00001,ko01000 Anthranilate synthase
PGHHMJKG_04391 0.0 pabB 2.6.1.85 - EH ko:K01665 ko00790,map00790 ko00000,ko00001,ko01000 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PGHHMJKG_04392 9.46e-198 yknT - - - ko:K06437 - ko00000 -
PGHHMJKG_04393 9.21e-142 mobA 2.7.7.77 - H ko:K03752 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PGHHMJKG_04394 7.59e-245 moeB 2.7.7.73, 2.7.7.80 - H ko:K03148,ko:K21029 ko00730,ko01100,ko04122,map00730,map01100,map04122 ko00000,ko00001,ko01000 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PGHHMJKG_04395 7.12e-312 moeA 2.10.1.1 - H ko:K03750 ko00790,ko01100,map00790,map01100 ko00000,ko00001,ko01000 molybdopterin
PGHHMJKG_04396 8.11e-121 mobB - - H ko:K03753 - ko00000 molybdopterin-guanine dinucleotide biosynthesis protein
PGHHMJKG_04397 6.61e-110 moaE 2.8.1.12 - H ko:K03635 ko00790,ko01100,ko04122,map00790,map01100,map04122 ko00000,ko00001,ko01000 COG0314 Molybdopterin converting factor, large subunit
PGHHMJKG_04398 2.82e-44 moaD - - H ko:K03636 ko04122,map04122 ko00000,ko00001 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PGHHMJKG_04399 0.0 yknU - - V ko:K06147,ko:K11085 ko02010,map02010 ko00000,ko00001,ko01000,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PGHHMJKG_04400 0.0 yknV - - V ko:K02021,ko:K06147,ko:K18890 ko02010,map02010 ko00000,ko00001,ko00002,ko02000 COG1132 ABC-type multidrug transport system, ATPase and permease components
PGHHMJKG_04401 1.31e-150 yknW - - S - - - Yip1 domain
PGHHMJKG_04402 8.16e-234 yknX - - M ko:K02005,ko:K13888 - ko00000,ko00002,ko02000 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PGHHMJKG_04403 3.53e-159 yknY - - V ko:K02003 - ko00000,ko00002,ko02000 ABC transporter, ATP-binding protein
PGHHMJKG_04404 5.51e-265 yknZ - - V ko:K02004 - ko00000,ko00002,ko02000 COG0577 ABC-type antimicrobial peptide transport system, permease component
PGHHMJKG_04405 1.75e-174 fruR - - K ko:K03436 - ko00000,ko03000 Transcriptional regulator
PGHHMJKG_04406 9.99e-216 pfkB 2.7.1.56 - G ko:K00882 ko00051,map00051 ko00000,ko00001,ko01000 Belongs to the carbohydrate kinase PfkB family
PGHHMJKG_04407 0.0 fruA 2.7.1.202 - GT ko:K02768,ko:K02769,ko:K02770 ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060 ko00000,ko00001,ko00002,ko01000,ko02000 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PGHHMJKG_04408 1.72e-134 sipT 3.4.21.89 - U ko:K03100 ko02024,ko03060,map02024,map03060 ko00000,ko00001,ko01000,ko01002 Belongs to the peptidase S26 family
PGHHMJKG_04409 5.43e-52 ykoA - - - - - - -
PGHHMJKG_04410 0.0 ykpA - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PGHHMJKG_04411 1.93e-213 panE1 1.1.1.169 - H ko:K00077 ko00770,ko01100,ko01110,map00770,map01100,map01110 ko00000,ko00001,ko00002,ko01000 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PGHHMJKG_04412 0.0 yvnB - - Q - - - Calcineurin-like phosphoesterase
PGHHMJKG_04413 5.23e-172 yvoA - - K ko:K03710 - ko00000,ko03000 transcriptional
PGHHMJKG_04414 1.74e-165 nagB 3.5.99.6 - G ko:K02564 ko00520,ko01100,map00520,map01100 ko00000,ko00001,ko01000 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PGHHMJKG_04415 5.07e-281 nagA 3.5.1.25 - G ko:K01443 ko00520,ko01130,map00520,map01130 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. NagA family
PGHHMJKG_04416 3.62e-217 hprK - - F ko:K06023 - ko00000,ko01000 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PGHHMJKG_04417 3.18e-195 lgt - - M ko:K13292 - ko00000,ko01000 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PGHHMJKG_04418 4.16e-208 yvoD - - P - - - COG0370 Fe2 transport system protein B
PGHHMJKG_04419 3.05e-153 ppaX 3.6.1.1 - S ko:K06019 ko00190,map00190 ko00000,ko00001,ko01000 Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PGHHMJKG_04420 5.94e-118 yvoF 2.3.1.79 - S ko:K00661 - ko00000,ko01000 COG0110 Acetyltransferase (isoleucine patch superfamily)
PGHHMJKG_04421 9.33e-108 - - - S - - - Protein of unknown function (DUF3800)
PGHHMJKG_04425 4.49e-136 rapK - - S ko:K06369 ko02024,map02024 ko00000,ko00001,ko01000 aspartate phosphatase
PGHHMJKG_04426 3.29e-104 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PGHHMJKG_04427 2.06e-85 yurT - - E - - - Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PGHHMJKG_04428 1.25e-56 - - - K - - - helix_turn_helix, Arsenical Resistance Operon Repressor
PGHHMJKG_04429 2.51e-13 - - - - - - - -
PGHHMJKG_04431 0.0 - - - L ko:K21487 - ko00000,ko01000,ko02048 A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PGHHMJKG_04432 4.02e-109 - - - S ko:K21488 - ko00000,ko02048 SMI1-KNR4 cell-wall
PGHHMJKG_04433 2.07e-303 pepS - - E ko:K19689 - ko00000,ko01000,ko01002 COG2309 Leucyl aminopeptidase (aminopeptidase T)
PGHHMJKG_04434 1.09e-18 - - - S - - - Uncharacterized protein YkpC
PGHHMJKG_04435 8.77e-234 mreBH - - D ko:K03569 - ko00000,ko02048,ko03036,ko04812 Rod-share determining protein MreBH
PGHHMJKG_04436 2.63e-58 abrB - - K ko:K06284 - ko00000,ko03000 of stationary sporulation gene expression
PGHHMJKG_04437 4.59e-307 kinC 2.7.13.3 - T ko:K07698 ko02020,map02020 ko00000,ko00001,ko00002,ko01000,ko01001,ko02022 COG0642 Signal transduction histidine kinase
PGHHMJKG_04438 8.84e-206 ykqA - - P - - - Gamma-glutamyl cyclotransferase, AIG2-like
PGHHMJKG_04439 1.68e-148 ktrA - - P ko:K03499 - ko00000,ko02000 COG0569 K transport systems, NAD-binding component
PGHHMJKG_04440 0.0 ade 3.5.4.2 - F ko:K01486 ko00230,ko01100,map00230,map01100 ko00000,ko00001,ko01000 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PGHHMJKG_04441 0.0 rnjA - - S ko:K12574 ko03018,map03018 ko00000,ko00001,ko01000,ko03019 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PGHHMJKG_04442 8.98e-42 ykzG - - S - - - Belongs to the UPF0356 family
PGHHMJKG_04443 8.28e-187 ykrA - - S - - - hydrolases of the HAD superfamily
PGHHMJKG_04444 3.96e-131 def 3.5.1.88 - J ko:K01462 - ko00000,ko01000 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PGHHMJKG_04445 2.24e-19 - - - S - - - Protein of unknown function (Tiny_TM_bacill)
PGHHMJKG_04446 6.82e-149 ykyA - - L - - - Putative cell-wall binding lipoprotein
PGHHMJKG_04447 1.51e-258 pdhA 1.2.4.1 - C ko:K00161 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PGHHMJKG_04448 3.52e-227 pdhB 1.2.4.1 - C ko:K00162 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230 br01601,ko00000,ko00001,ko00002,ko01000 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PGHHMJKG_04449 5.96e-301 pdhC 2.3.1.12 - C ko:K00627 ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PGHHMJKG_04450 0.0 pdhD 1.8.1.4 - C ko:K00382 ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200 br01601,ko00000,ko00001,ko00002,ko01000,ko04147 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PGHHMJKG_04451 4.55e-83 slp - - CO - - - COG0526, thiol-disulfide isomerase and thioredoxins
PGHHMJKG_04453 1.18e-252 - - - L - - - COG3385 FOG Transposase and inactivated derivatives
PGHHMJKG_04454 3.03e-74 flaG - - N ko:K06603 - ko00000,ko02035 flagellar protein FlaG
PGHHMJKG_04455 0.0 fliD - - N ko:K02407 ko02040,map02040 ko00000,ko00001,ko02035 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PGHHMJKG_04456 6.02e-90 fliS - - N ko:K02422 ko02040,map02040 ko00000,ko00001,ko02035 flagellar protein FliS
PGHHMJKG_04457 8.69e-09 fliT - - S ko:K02423 ko02040,map02040 ko00000,ko00001,ko02035 bacterial-type flagellum organization
PGHHMJKG_04458 2.46e-67 - - - - - - - -
PGHHMJKG_04459 1.73e-132 hpf - - J ko:K05808 - ko00000,ko03009 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PGHHMJKG_04460 6.53e-108 yuaE - - S - - - DinB superfamily
PGHHMJKG_04461 1.68e-109 yuaF - - OU - - - Membrane protein implicated in regulation of membrane protease activity
PGHHMJKG_04462 9.14e-258 yuaG - - S ko:K07192 ko04910,map04910 ko00000,ko00001,ko03036,ko04131,ko04147 protein conserved in bacteria
PGHHMJKG_04463 5.71e-121 - - - M - - - FR47-like protein
PGHHMJKG_04464 2.52e-122 thiT - - S ko:K16789 - ko00000,ko02000 Thiamine transporter protein (Thia_YuaJ)
PGHHMJKG_04465 2.88e-186 - - - L ko:K07497 - ko00000 Molecular Function DNA binding, Biological Process DNA recombination
PGHHMJKG_04466 3.26e-72 - - - L - - - transposase activity
PGHHMJKG_04467 2.29e-29 ywtC - - - - - - -
PGHHMJKG_04468 1.33e-277 capA - - M ko:K07282 - ko00000 enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PGHHMJKG_04469 8.44e-91 capC - - S ko:K22116 - ko00000 biosynthesis protein
PGHHMJKG_04470 1.46e-283 capB - - M ko:K01932 - ko00000,ko01000 COG0769 UDP-N-acetylmuramyl tripeptide synthase
PGHHMJKG_04473 0.000711 - - - - - - - -
PGHHMJKG_04474 3.6e-117 - - - L - - - TIGRFAM Transposase, IS605 OrfB, C-terminal
PGHHMJKG_04476 7.27e-26 - - - K - - - Cro/C1-type HTH DNA-binding domain
PGHHMJKG_04478 1.86e-98 yfmK 2.3.1.128 - K ko:K03790 - ko00000,ko01000,ko03009 acetyltransferase
PGHHMJKG_04479 1.4e-261 yfmL - - L - - - COG0513 Superfamily II DNA and RNA helicases
PGHHMJKG_04480 0.0 yheS_1 - - S - - - COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PGHHMJKG_04482 3.12e-104 yndB - - S - - - Activator of Hsp90 ATPase homolog 1-like protein
PGHHMJKG_04483 8.92e-96 - - - - - - - -
PGHHMJKG_04484 2.37e-34 tatA - - U ko:K03116,ko:K03117,ko:K03646 ko03060,ko03070,map03060,map03070 ko00000,ko00001,ko00002,ko02000,ko02044 protein secretion
PGHHMJKG_04487 2.43e-162 - - - S - - - Domain of unknown function, YrpD
PGHHMJKG_04491 1.79e-74 - - - S - - - Bacteriophage holin family
PGHHMJKG_04492 5.85e-164 - - - - - - - -
PGHHMJKG_04493 3.25e-137 - - - L - - - DNA ligase (ATP) activity
PGHHMJKG_04496 2.47e-268 VCP - - O - - - AAA domain (dynein-related subfamily)
PGHHMJKG_04497 2.71e-103 yjoA - - S - - - DinB family

eggNOG-mapper v2.1.12 (Database: eggNOG v5.0.2, Mar. 2021 release)